id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-021494-9glqvzfx	Funkhouser, William K.	Pathology: The Clinical Description of Human Disease	2012-07-27		.txt	text/plain	2798	151	37	The mental construct of etiology (cause), pathogenesis (progression), natural history (clinical outcome), and response to therapy is the standard approach for pathologists thinking about a disease. Diagnostic pathology will continue to use morphology and complementary data from protein (immunohistochemical) and nucleic acid (cytogenetics, in situ hybridization, DNA sequence, and RNA abundance) screening assays. It is possible that each new neoplasm will be promptly defined as to ploidy, translocations, gene copy number differences, DNA mutations, and RNA expression cluster subset, allowing residual disease screening as well as individualized therapy. Pathologists diagnose disease by generating a differential diagnosis, then finding the best fit for the clinical presentation, the radiographic appearance, and the pathologic (both clinical lab and morphologic) findings. Pathologists diagnose disease by generating a differential diagnosis, then finding the best fit for the clinical presentation, the radiographic appearance, and the pathologic (both clinical lab and morphologic) findings.	./cache/cord-021494-9glqvzfx.txt	./txt/cord-021494-9glqvzfx.txt