id author title date pages extension mime words sentences flesch summary cache txt cord-017702-v46ye328 Ganguly, Nirmal Kumar Pharmacogenomics and Personalized Medicine for Infectious Diseases 2013-06-11 .txt text/plain 16564 798 43 Deciphering the pathogen virulence factors, host susceptibility genes, and the molecular programs involved in the pathogenesis of disease has paved the way for discovery of new molecular targets for drugs, diagnostic markers, and vaccines. The pathogen genome on one hand gives us the information about the important genes conferring disease pathogenesis as well as drug resistance, while the genome of the host on the other hand will reveal the susceptibility genes, and the further knowledge of polymorphisms in genes of the host metabolic and immune system will lead to the new vaccine strategies, drugs targets, and also their treatment outcomes. Several fi eld studies have further suggested that there is a need for calibration of isoniazid dosage as per the individual tuberculosis patient's age, acetylator status, and disease process for an effective antimicrobial outcome of drug treatment (Jeena et al. ./cache/cord-017702-v46ye328.txt ./txt/cord-017702-v46ye328.txt