id author title date pages extension mime words sentences flesch summary cache txt cord-016364-80l5mua2 Menotti-Raymond, Marilyn The Domestic Cat, Felis catus, as a Model of Hereditary and Infectious Disease 2008 .txt text/plain 6905 380 40 Genomics tools developed in the cat, including the recent completion of the 2-fold whole genome sequence of the cat and genome browser, radiation hybrid map of 1793 integrated coding and microsatellite loci, a 5-cM genetic linkage map, arrayed BAC libraries, and flow sorted chromosomes, are providing resources that are being utilized in mapping and characterization of genes of interest. 8 Ninety-six percent of the 1793 cat markers have identifi able orthologues in the canine and human genome sequences, providing a rich comparative tool, which is critical in linkage mapping exercises for the identification of genes controlling feline phenotypes. However, with the availability of a detailed comparative map, and integration with developing GL and RH maps, and the cat 2X whole genome sequence, linkage and association-based mapping techniques have recently identified causative mutations for hereditary disease genes, 33, 34 as well as several feline phenotypes (Table 25-1) . ./cache/cord-016364-80l5mua2.txt ./txt/cord-016364-80l5mua2.txt