id author title date pages extension mime words sentences flesch summary cache txt cord-009966-6kcgc5fx Warren, Kimberly R. Role of chronic stress and depression in periodontal diseases 2013-12-09 .txt text/plain 6818 332 30 Epidemiologic studies provide strong evidence that chronic psychosocial stress and depression increase the risk of atherosclerotic cardiovascular disease, diabetes and other systemic conditions (51) , as well as adversely affect the course and outcome of the conditions (85, 100, 138) . Evidence also indicates that chronic stress and depression can mediate risk and progression of periodontitis through changes in health-related behaviors, such as oral hygiene, smoking and diet (3, 45) . Of the 14 studies (seven case-control, six cross-sectional and one prospective clinical trial) meeting inclusion criteria for the review, the majority (57%) reported a positive relationship between stress/psychological factors and periodontal disease. This study revealed that psychosocial measures of stress (financial strain) and distress, manifest as depression, were significant risk indicators of periodontal disease severity in adults, after adjusting for gender (male), smoking, diabetes mellitus, T. ./cache/cord-009966-6kcgc5fx.txt ./txt/cord-009966-6kcgc5fx.txt