id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-306204-rkher4ly	Pong, Lian Yih	Anti-dengue virus serotype 2 activity of tannins from porcupine dates	2020-05-20		.txt	text/plain	6060	318	54	Vero cells grown in 24-well plates were infected with 30-50 FFU of DENV-2 in the presence or absence of BDTF, PDTF, methanol crude extracts, tannic acids of FT and ST at maximum non-toxic concentration (MNTC) of 100 µg/ mL, 50 µg/mL, 200 µg/mL, 50 µg/mL and 25 µg/mL respectively for 1 h at 4 °C. To study whether tannins in the porcupine dates are bioactive against dengue infection, we have isolated the tannin fractions from MBD and MPD for Besides that, both BDTF and PDTF demonstrated similar and higher virucidal activity against DENV-2 when compared to their methanol crude extracts. " indicates not significant Fig. 9 Effect of pre-treatment with porcupine dates extracts and tannic acids on DENV-2 infection in Vero cells. The antiviral activity ascribed to the interaction between the extracts and host cells was also investigated; pre-treating the cells with BDTF prevented the DENV-2 infection by at least 75% and similar result was observed for FT tannic acid.	./cache/cord-306204-rkher4ly.txt	./txt/cord-306204-rkher4ly.txt