id sid tid token lemma pos cord-354833-vvlsqy36 1 1 key key JJ cord-354833-vvlsqy36 1 2 : : : cord-354833-vvlsqy36 1 3 cord-354833-vvlsqy36 cord-354833-vvlsqy36 NN cord-354833-vvlsqy36 1 4 authors author NNS cord-354833-vvlsqy36 1 5 : : : cord-354833-vvlsqy36 1 6 Peters Peters NNP cord-354833-vvlsqy36 1 7 , , , cord-354833-vvlsqy36 1 8 Bjoern Bjoern NNP cord-354833-vvlsqy36 1 9 ; ; : cord-354833-vvlsqy36 1 10 Sette Sette NNP cord-354833-vvlsqy36 1 11 , , , cord-354833-vvlsqy36 1 12 Alessandro Alessandro NNP cord-354833-vvlsqy36 1 13 title title NN cord-354833-vvlsqy36 1 14 : : : cord-354833-vvlsqy36 1 15 Integrating integrate VBG cord-354833-vvlsqy36 1 16 epitope epitope NN cord-354833-vvlsqy36 1 17 data datum NNS cord-354833-vvlsqy36 1 18 into into IN cord-354833-vvlsqy36 1 19 the the DT cord-354833-vvlsqy36 1 20 emerging emerge VBG cord-354833-vvlsqy36 1 21 web web NN cord-354833-vvlsqy36 1 22 of of IN cord-354833-vvlsqy36 1 23 biomedical biomedical JJ cord-354833-vvlsqy36 1 24 knowledge knowledge NN cord-354833-vvlsqy36 1 25 resources resource NNS cord-354833-vvlsqy36 1 26 date date NN cord-354833-vvlsqy36 1 27 : : : cord-354833-vvlsqy36 2 1 2007 2007 CD cord-354833-vvlsqy36 2 2 journal journal NNP cord-354833-vvlsqy36 2 3 : : : cord-354833-vvlsqy36 3 1 Nat Nat NNP cord-354833-vvlsqy36 3 2 Rev Rev NNP cord-354833-vvlsqy36 3 3 Immunol Immunol NNP cord-354833-vvlsqy36 3 4 DOI DOI NNP cord-354833-vvlsqy36 3 5 : : : cord-354833-vvlsqy36 4 1 10.1038 10.1038 CD cord-354833-vvlsqy36 4 2 / / SYM cord-354833-vvlsqy36 4 3 nri2092 nri2092 NNP cord-354833-vvlsqy36 4 4 sha sha NNP cord-354833-vvlsqy36 5 1 : : : cord-354833-vvlsqy36 5 2 8677f927884b758840ec233ecea216c06074ad09 8677f927884b758840ec233ecea216c06074ad09 CD cord-354833-vvlsqy36 5 3 doc_id doc_id CD cord-354833-vvlsqy36 5 4 : : : cord-354833-vvlsqy36 5 5 354833 354833 CD cord-354833-vvlsqy36 5 6 cord_uid cord_uid NN cord-354833-vvlsqy36 5 7 : : : cord-354833-vvlsqy36 6 1 vvlsqy36 vvlsqy36 NNP cord-354833-vvlsqy36 7 1 The the DT cord-354833-vvlsqy36 7 2 recognition recognition NN cord-354833-vvlsqy36 7 3 of of IN cord-354833-vvlsqy36 7 4 immune immune JJ cord-354833-vvlsqy36 7 5 epitopes epitope NNS cord-354833-vvlsqy36 7 6 is be VBZ cord-354833-vvlsqy36 7 7 an an DT cord-354833-vvlsqy36 7 8 important important JJ cord-354833-vvlsqy36 7 9 molecular molecular JJ cord-354833-vvlsqy36 7 10 mechanism mechanism NN cord-354833-vvlsqy36 7 11 of of IN cord-354833-vvlsqy36 7 12 the the DT cord-354833-vvlsqy36 7 13 vertebrate vertebrate JJ cord-354833-vvlsqy36 7 14 immune immune JJ cord-354833-vvlsqy36 7 15 system system NN cord-354833-vvlsqy36 7 16 to to TO cord-354833-vvlsqy36 7 17 discriminate discriminate VB cord-354833-vvlsqy36 7 18 between between IN cord-354833-vvlsqy36 7 19 self self NN cord-354833-vvlsqy36 7 20 and and CC cord-354833-vvlsqy36 7 21 non non JJ cord-354833-vvlsqy36 7 22 - - JJ cord-354833-vvlsqy36 7 23 self self JJ cord-354833-vvlsqy36 7 24 . . . cord-354833-vvlsqy36 8 1 Increasing increase VBG cord-354833-vvlsqy36 8 2 amounts amount NNS cord-354833-vvlsqy36 8 3 of of IN cord-354833-vvlsqy36 8 4 data datum NNS cord-354833-vvlsqy36 8 5 on on IN cord-354833-vvlsqy36 8 6 immune immune JJ cord-354833-vvlsqy36 8 7 epitopes epitope NNS cord-354833-vvlsqy36 8 8 are be VBP cord-354833-vvlsqy36 8 9 becoming become VBG cord-354833-vvlsqy36 8 10 available available JJ cord-354833-vvlsqy36 8 11 due due IN cord-354833-vvlsqy36 8 12 to to IN cord-354833-vvlsqy36 8 13 technological technological JJ cord-354833-vvlsqy36 8 14 advances advance NNS cord-354833-vvlsqy36 8 15 in in IN cord-354833-vvlsqy36 8 16 epitope epitope NN cord-354833-vvlsqy36 8 17 - - HYPH cord-354833-vvlsqy36 8 18 mapping mapping NN cord-354833-vvlsqy36 8 19 techniques technique NNS cord-354833-vvlsqy36 8 20 and and CC cord-354833-vvlsqy36 8 21 the the DT cord-354833-vvlsqy36 8 22 availability availability NN cord-354833-vvlsqy36 8 23 of of IN cord-354833-vvlsqy36 8 24 genomic genomic JJ cord-354833-vvlsqy36 8 25 information information NN cord-354833-vvlsqy36 8 26 for for IN cord-354833-vvlsqy36 8 27 pathogens pathogen NNS cord-354833-vvlsqy36 8 28 . . . cord-354833-vvlsqy36 9 1 Organizing organize VBG cord-354833-vvlsqy36 9 2 this this DT cord-354833-vvlsqy36 9 3 data data NN cord-354833-vvlsqy36 9 4 poses pose VBZ cord-354833-vvlsqy36 9 5 a a DT cord-354833-vvlsqy36 9 6 challenge challenge NN cord-354833-vvlsqy36 9 7 that that WDT cord-354833-vvlsqy36 9 8 is be VBZ cord-354833-vvlsqy36 9 9 similar similar JJ cord-354833-vvlsqy36 9 10 to to IN cord-354833-vvlsqy36 9 11 the the DT cord-354833-vvlsqy36 9 12 successful successful JJ cord-354833-vvlsqy36 9 13 effort effort NN cord-354833-vvlsqy36 9 14 that that WDT cord-354833-vvlsqy36 9 15 was be VBD cord-354833-vvlsqy36 9 16 required require VBN cord-354833-vvlsqy36 9 17 to to TO cord-354833-vvlsqy36 9 18 organize organize VB cord-354833-vvlsqy36 9 19 genomic genomic JJ cord-354833-vvlsqy36 9 20 data datum NNS cord-354833-vvlsqy36 9 21 , , , cord-354833-vvlsqy36 9 22 which which WDT cord-354833-vvlsqy36 9 23 needed need VBD cord-354833-vvlsqy36 9 24 the the DT cord-354833-vvlsqy36 9 25 establishment establishment NN cord-354833-vvlsqy36 9 26 of of IN cord-354833-vvlsqy36 9 27 centralized centralized JJ cord-354833-vvlsqy36 9 28 databases database NNS cord-354833-vvlsqy36 9 29 that that WDT cord-354833-vvlsqy36 9 30 complement complement VBP cord-354833-vvlsqy36 9 31 the the DT cord-354833-vvlsqy36 9 32 primary primary JJ cord-354833-vvlsqy36 9 33 literature literature NN cord-354833-vvlsqy36 9 34 to to TO cord-354833-vvlsqy36 9 35 make make VB cord-354833-vvlsqy36 9 36 the the DT cord-354833-vvlsqy36 9 37 data datum NNS cord-354833-vvlsqy36 9 38 readily readily RB cord-354833-vvlsqy36 9 39 accessible accessible JJ cord-354833-vvlsqy36 9 40 and and CC cord-354833-vvlsqy36 9 41 searchable searchable JJ cord-354833-vvlsqy36 9 42 by by IN cord-354833-vvlsqy36 9 43 researchers researcher NNS cord-354833-vvlsqy36 9 44 . . . cord-354833-vvlsqy36 10 1 As as IN cord-354833-vvlsqy36 10 2 described describe VBN cord-354833-vvlsqy36 10 3 in in IN cord-354833-vvlsqy36 10 4 this this DT cord-354833-vvlsqy36 10 5 Innovation Innovation NNP cord-354833-vvlsqy36 10 6 article article NN cord-354833-vvlsqy36 10 7 , , , cord-354833-vvlsqy36 10 8 the the DT cord-354833-vvlsqy36 10 9 Immune Immune NNP cord-354833-vvlsqy36 10 10 Epitope Epitope NNP cord-354833-vvlsqy36 10 11 Database Database NNP cord-354833-vvlsqy36 10 12 and and CC cord-354833-vvlsqy36 10 13 Analysis Analysis NNP cord-354833-vvlsqy36 10 14 Resource Resource NNP cord-354833-vvlsqy36 10 15 aims aim VBZ cord-354833-vvlsqy36 10 16 to to TO cord-354833-vvlsqy36 10 17 achieve achieve VB cord-354833-vvlsqy36 10 18 the the DT cord-354833-vvlsqy36 10 19 same same JJ cord-354833-vvlsqy36 10 20 for for IN cord-354833-vvlsqy36 10 21 the the DT cord-354833-vvlsqy36 10 22 more more RBR cord-354833-vvlsqy36 10 23 complex complex JJ cord-354833-vvlsqy36 10 24 and and CC cord-354833-vvlsqy36 10 25 context context NN cord-354833-vvlsqy36 10 26 - - HYPH cord-354833-vvlsqy36 10 27 dependent dependent JJ cord-354833-vvlsqy36 10 28 information information NN cord-354833-vvlsqy36 10 29 on on IN cord-354833-vvlsqy36 10 30 immune immune JJ cord-354833-vvlsqy36 10 31 epitopes epitope NNS cord-354833-vvlsqy36 10 32 , , , cord-354833-vvlsqy36 10 33 and and CC cord-354833-vvlsqy36 10 34 to to TO cord-354833-vvlsqy36 10 35 integrate integrate VB cord-354833-vvlsqy36 10 36 this this DT cord-354833-vvlsqy36 10 37 data datum NNS cord-354833-vvlsqy36 10 38 with with IN cord-354833-vvlsqy36 10 39 existing exist VBG cord-354833-vvlsqy36 10 40 and and CC cord-354833-vvlsqy36 10 41 emerging emerge VBG cord-354833-vvlsqy36 10 42 knowledge knowledge NN cord-354833-vvlsqy36 10 43 resources resource NNS cord-354833-vvlsqy36 10 44 . . . cord-354833-vvlsqy36 11 1 Integrating integrate VBG cord-354833-vvlsqy36 11 2 epitope epitope NN cord-354833-vvlsqy36 11 3 data datum NNS cord-354833-vvlsqy36 11 4 into into IN cord-354833-vvlsqy36 11 5 the the DT cord-354833-vvlsqy36 11 6 emerging emerge VBG cord-354833-vvlsqy36 11 7 web web NN cord-354833-vvlsqy36 11 8 of of IN cord-354833-vvlsqy36 11 9 biomedical biomedical JJ cord-354833-vvlsqy36 11 10 knowledge knowledge NN cord-354833-vvlsqy36 11 11 resources resource NNS cord-354833-vvlsqy36 12 1 Abstract Abstract NNP cord-354833-vvlsqy36 12 2 | | NNP cord-354833-vvlsqy36 13 1 The the DT cord-354833-vvlsqy36 13 2 recognition recognition NN cord-354833-vvlsqy36 13 3 of of IN cord-354833-vvlsqy36 13 4 immune immune JJ cord-354833-vvlsqy36 13 5 epitopes epitope NNS cord-354833-vvlsqy36 13 6 is be VBZ cord-354833-vvlsqy36 13 7 an an DT cord-354833-vvlsqy36 13 8 important important JJ cord-354833-vvlsqy36 13 9 molecular molecular JJ cord-354833-vvlsqy36 13 10 mechanism mechanism NN cord-354833-vvlsqy36 13 11 of of IN cord-354833-vvlsqy36 13 12 the the DT cord-354833-vvlsqy36 13 13 vertebrate vertebrate JJ cord-354833-vvlsqy36 13 14 immune immune JJ cord-354833-vvlsqy36 13 15 system system NN cord-354833-vvlsqy36 13 16 to to TO cord-354833-vvlsqy36 13 17 discriminate discriminate VB cord-354833-vvlsqy36 13 18 between between IN cord-354833-vvlsqy36 13 19 self self NN cord-354833-vvlsqy36 13 20 and and CC cord-354833-vvlsqy36 13 21 non non JJ cord-354833-vvlsqy36 13 22 - - JJ cord-354833-vvlsqy36 13 23 self self JJ cord-354833-vvlsqy36 13 24 . . . cord-354833-vvlsqy36 14 1 Increasing increase VBG cord-354833-vvlsqy36 14 2 amounts amount NNS cord-354833-vvlsqy36 14 3 of of IN cord-354833-vvlsqy36 14 4 data datum NNS cord-354833-vvlsqy36 14 5 on on IN cord-354833-vvlsqy36 14 6 immune immune JJ cord-354833-vvlsqy36 14 7 epitopes epitope NNS cord-354833-vvlsqy36 14 8 are be VBP cord-354833-vvlsqy36 14 9 becoming become VBG cord-354833-vvlsqy36 14 10 available available JJ cord-354833-vvlsqy36 14 11 due due IN cord-354833-vvlsqy36 14 12 to to IN cord-354833-vvlsqy36 14 13 technological technological JJ cord-354833-vvlsqy36 14 14 advances advance NNS cord-354833-vvlsqy36 14 15 in in IN cord-354833-vvlsqy36 14 16 epitope epitope NN cord-354833-vvlsqy36 14 17 - - HYPH cord-354833-vvlsqy36 14 18 mapping mapping NN cord-354833-vvlsqy36 14 19 techniques technique NNS cord-354833-vvlsqy36 14 20 and and CC cord-354833-vvlsqy36 14 21 the the DT cord-354833-vvlsqy36 14 22 availability availability NN cord-354833-vvlsqy36 14 23 of of IN cord-354833-vvlsqy36 14 24 genomic genomic JJ cord-354833-vvlsqy36 14 25 information information NN cord-354833-vvlsqy36 14 26 for for IN cord-354833-vvlsqy36 14 27 pathogens pathogen NNS cord-354833-vvlsqy36 14 28 . . . cord-354833-vvlsqy36 15 1 Organizing organize VBG cord-354833-vvlsqy36 15 2 this this DT cord-354833-vvlsqy36 15 3 data data NN cord-354833-vvlsqy36 15 4 poses pose VBZ cord-354833-vvlsqy36 15 5 a a DT cord-354833-vvlsqy36 15 6 challenge challenge NN cord-354833-vvlsqy36 15 7 that that WDT cord-354833-vvlsqy36 15 8 is be VBZ cord-354833-vvlsqy36 15 9 similar similar JJ cord-354833-vvlsqy36 15 10 to to IN cord-354833-vvlsqy36 15 11 the the DT cord-354833-vvlsqy36 15 12 successful successful JJ cord-354833-vvlsqy36 15 13 effort effort NN cord-354833-vvlsqy36 15 14 that that WDT cord-354833-vvlsqy36 15 15 was be VBD cord-354833-vvlsqy36 15 16 required require VBN cord-354833-vvlsqy36 15 17 to to TO cord-354833-vvlsqy36 15 18 organize organize VB cord-354833-vvlsqy36 15 19 genomic genomic JJ cord-354833-vvlsqy36 15 20 data datum NNS cord-354833-vvlsqy36 15 21 , , , cord-354833-vvlsqy36 15 22 which which WDT cord-354833-vvlsqy36 15 23 needed need VBD cord-354833-vvlsqy36 15 24 the the DT cord-354833-vvlsqy36 15 25 establishment establishment NN cord-354833-vvlsqy36 15 26 of of IN cord-354833-vvlsqy36 15 27 centralized centralized JJ cord-354833-vvlsqy36 15 28 databases database NNS cord-354833-vvlsqy36 15 29 that that WDT cord-354833-vvlsqy36 15 30 complement complement VBP cord-354833-vvlsqy36 15 31 the the DT cord-354833-vvlsqy36 15 32 primary primary JJ cord-354833-vvlsqy36 15 33 literature literature NN cord-354833-vvlsqy36 15 34 to to TO cord-354833-vvlsqy36 15 35 make make VB cord-354833-vvlsqy36 15 36 the the DT cord-354833-vvlsqy36 15 37 data datum NNS cord-354833-vvlsqy36 15 38 readily readily RB cord-354833-vvlsqy36 15 39 accessible accessible JJ cord-354833-vvlsqy36 15 40 and and CC cord-354833-vvlsqy36 15 41 searchable searchable JJ cord-354833-vvlsqy36 15 42 by by IN cord-354833-vvlsqy36 15 43 researchers researcher NNS cord-354833-vvlsqy36 15 44 . . . cord-354833-vvlsqy36 16 1 As as IN cord-354833-vvlsqy36 16 2 described describe VBN cord-354833-vvlsqy36 16 3 in in IN cord-354833-vvlsqy36 16 4 this this DT cord-354833-vvlsqy36 16 5 Innovation Innovation NNP cord-354833-vvlsqy36 16 6 article article NN cord-354833-vvlsqy36 16 7 , , , cord-354833-vvlsqy36 16 8 the the DT cord-354833-vvlsqy36 16 9 Immune Immune NNP cord-354833-vvlsqy36 16 10 Epitope Epitope NNP cord-354833-vvlsqy36 16 11 Database Database NNP cord-354833-vvlsqy36 16 12 and and CC cord-354833-vvlsqy36 16 13 Analysis Analysis NNP cord-354833-vvlsqy36 16 14 Resource Resource NNP cord-354833-vvlsqy36 16 15 aims aim VBZ cord-354833-vvlsqy36 16 16 to to TO cord-354833-vvlsqy36 16 17 achieve achieve VB cord-354833-vvlsqy36 16 18 the the DT cord-354833-vvlsqy36 16 19 same same JJ cord-354833-vvlsqy36 16 20 for for IN cord-354833-vvlsqy36 16 21 the the DT cord-354833-vvlsqy36 16 22 more more RBR cord-354833-vvlsqy36 16 23 complex complex JJ cord-354833-vvlsqy36 16 24 and and CC cord-354833-vvlsqy36 16 25 context context NN cord-354833-vvlsqy36 16 26 - - HYPH cord-354833-vvlsqy36 16 27 dependent dependent JJ cord-354833-vvlsqy36 16 28 information information NN cord-354833-vvlsqy36 16 29 on on IN cord-354833-vvlsqy36 16 30 immune immune JJ cord-354833-vvlsqy36 16 31 epitopes epitope NNS cord-354833-vvlsqy36 16 32 , , , cord-354833-vvlsqy36 16 33 and and CC cord-354833-vvlsqy36 16 34 to to TO cord-354833-vvlsqy36 16 35 integrate integrate VB cord-354833-vvlsqy36 16 36 this this DT cord-354833-vvlsqy36 16 37 data datum NNS cord-354833-vvlsqy36 16 38 with with IN cord-354833-vvlsqy36 16 39 existing exist VBG cord-354833-vvlsqy36 16 40 and and CC cord-354833-vvlsqy36 16 41 emerging emerge VBG cord-354833-vvlsqy36 16 42 knowledge knowledge NN cord-354833-vvlsqy36 16 43 resources resource NNS cord-354833-vvlsqy36 16 44 . . . cord-354833-vvlsqy36 17 1 In in IN cord-354833-vvlsqy36 17 2 this this DT cord-354833-vvlsqy36 17 3 age age NN cord-354833-vvlsqy36 17 4 of of IN cord-354833-vvlsqy36 17 5 information information NN cord-354833-vvlsqy36 17 6 - - : cord-354833-vvlsqy36 17 7 and and CC cord-354833-vvlsqy36 17 8 technologydriven technologydriven NNP cord-354833-vvlsqy36 17 9 research research NN cord-354833-vvlsqy36 17 10 , , , cord-354833-vvlsqy36 17 11 keeping keep VBG cord-354833-vvlsqy36 17 12 up up RP cord-354833-vvlsqy36 17 13 with with IN cord-354833-vvlsqy36 17 14 the the DT cord-354833-vvlsqy36 17 15 large large JJ cord-354833-vvlsqy36 17 16 amounts amount NNS cord-354833-vvlsqy36 17 17 of of IN cord-354833-vvlsqy36 17 18 published publish VBN cord-354833-vvlsqy36 17 19 data data NN cord-354833-vvlsqy36 17 20 is be VBZ cord-354833-vvlsqy36 17 21 overwhelming overwhelming JJ cord-354833-vvlsqy36 17 22 for for IN cord-354833-vvlsqy36 17 23 any any DT cord-354833-vvlsqy36 17 24 researcher researcher NN cord-354833-vvlsqy36 17 25 , , , cord-354833-vvlsqy36 17 26 particularly particularly RB cord-354833-vvlsqy36 17 27 in in IN cord-354833-vvlsqy36 17 28 areas area NNS cord-354833-vvlsqy36 17 29 not not RB cord-354833-vvlsqy36 17 30 related related JJ cord-354833-vvlsqy36 17 31 to to IN cord-354833-vvlsqy36 17 32 their -PRON- PRP$ cord-354833-vvlsqy36 17 33 primary primary JJ cord-354833-vvlsqy36 17 34 expertise expertise NN cord-354833-vvlsqy36 17 35 . . . cord-354833-vvlsqy36 18 1 To to TO cord-354833-vvlsqy36 18 2 benefit benefit VB cord-354833-vvlsqy36 18 3 from from IN cord-354833-vvlsqy36 18 4 published publish VBN cord-354833-vvlsqy36 18 5 data datum NNS cord-354833-vvlsqy36 18 6 , , , cord-354833-vvlsqy36 18 7 it -PRON- PRP cord-354833-vvlsqy36 18 8 is be VBZ cord-354833-vvlsqy36 18 9 increasingly increasingly RB cord-354833-vvlsqy36 18 10 stored store VBN cord-354833-vvlsqy36 18 11 in in IN cord-354833-vvlsqy36 18 12 dedicated dedicated JJ cord-354833-vvlsqy36 18 13 searchable searchable JJ cord-354833-vvlsqy36 18 14 databases database NNS cord-354833-vvlsqy36 18 15 . . . cord-354833-vvlsqy36 19 1 There there EX cord-354833-vvlsqy36 19 2 is be VBZ cord-354833-vvlsqy36 19 3 a a DT cord-354833-vvlsqy36 19 4 family family NN cord-354833-vvlsqy36 19 5 of of IN cord-354833-vvlsqy36 19 6 such such JJ cord-354833-vvlsqy36 19 7 established establish VBN cord-354833-vvlsqy36 19 8 databases database NNS cord-354833-vvlsqy36 19 9 , , , cord-354833-vvlsqy36 19 10 which which WDT cord-354833-vvlsqy36 19 11 includes include VBZ cord-354833-vvlsqy36 19 12 SwissProt SwissProt NNP cord-354833-vvlsqy36 19 13 , , , cord-354833-vvlsqy36 19 14 the the DT cord-354833-vvlsqy36 19 15 Research Research NNP cord-354833-vvlsqy36 19 16 Collaboratory Collaboratory NNP cord-354833-vvlsqy36 19 17 for for IN cord-354833-vvlsqy36 19 18 Structural Structural NNP cord-354833-vvlsqy36 19 19 Bioinformatics Bioinformatics NNP cord-354833-vvlsqy36 19 20 ( ( -LRB- cord-354833-vvlsqy36 19 21 RCSB RCSB NNP cord-354833-vvlsqy36 19 22 ) ) -RRB- cord-354833-vvlsqy36 20 1 Protein Protein NNP cord-354833-vvlsqy36 20 2 Data Data NNP cord-354833-vvlsqy36 20 3 Bank Bank NNP cord-354833-vvlsqy36 20 4 ( ( -LRB- cord-354833-vvlsqy36 20 5 PDB PDB NNP cord-354833-vvlsqy36 20 6 ) ) -RRB- cord-354833-vvlsqy36 20 7 and and CC cord-354833-vvlsqy36 20 8 the the DT cord-354833-vvlsqy36 20 9 National National NNP cord-354833-vvlsqy36 20 10 Center Center NNP cord-354833-vvlsqy36 20 11 for for IN cord-354833-vvlsqy36 20 12 Biotechnology Biotechnology NNP cord-354833-vvlsqy36 20 13 Information Information NNP cord-354833-vvlsqy36 20 14 ( ( -LRB- cord-354833-vvlsqy36 20 15 NCBI NCBI NNP cord-354833-vvlsqy36 20 16 ) ) -RRB- cord-354833-vvlsqy36 20 17 databases database VBZ cord-354833-vvlsqy36 20 18 PubMed PubMed NNP cord-354833-vvlsqy36 20 19 , , , cord-354833-vvlsqy36 20 20 GenBank GenBank NNP cord-354833-vvlsqy36 20 21 and and CC cord-354833-vvlsqy36 20 22 Taxonomy Taxonomy NNP cord-354833-vvlsqy36 20 23 Browser Browser NNP cord-354833-vvlsqy36 20 24 ( ( -LRB- cord-354833-vvlsqy36 20 25 BOX BOX NNP cord-354833-vvlsqy36 20 26 1 1 CD cord-354833-vvlsqy36 20 27 ) ) -RRB- cord-354833-vvlsqy36 20 28 , , . cord-354833-vvlsqy36 21 1 all all DT cord-354833-vvlsqy36 21 2 of of IN cord-354833-vvlsqy36 21 3 which which WDT cord-354833-vvlsqy36 21 4 can can MD cord-354833-vvlsqy36 21 5 claim claim VB cord-354833-vvlsqy36 21 6 to to TO cord-354833-vvlsqy36 21 7 be be VB cord-354833-vvlsqy36 21 8 widely widely RB cord-354833-vvlsqy36 21 9 used use VBN cord-354833-vvlsqy36 21 10 as as IN cord-354833-vvlsqy36 21 11 the the DT cord-354833-vvlsqy36 21 12 major major JJ cord-354833-vvlsqy36 21 13 source source NN cord-354833-vvlsqy36 21 14 of of IN cord-354833-vvlsqy36 21 15 information information NN cord-354833-vvlsqy36 21 16 in in IN cord-354833-vvlsqy36 21 17 their -PRON- PRP$ cord-354833-vvlsqy36 21 18 domains domain NNS cord-354833-vvlsqy36 21 19 . . . cord-354833-vvlsqy36 22 1 Today today NN cord-354833-vvlsqy36 22 2 , , , cord-354833-vvlsqy36 22 3 researchers researcher NNS cord-354833-vvlsqy36 22 4 are be VBP cord-354833-vvlsqy36 22 5 much much RB cord-354833-vvlsqy36 22 6 more more RBR cord-354833-vvlsqy36 22 7 likely likely JJ cord-354833-vvlsqy36 22 8 to to TO cord-354833-vvlsqy36 22 9 retrieve retrieve VB cord-354833-vvlsqy36 22 10 a a DT cord-354833-vvlsqy36 22 11 protein protein NN cord-354833-vvlsqy36 22 12 sequence sequence NN cord-354833-vvlsqy36 22 13 from from IN cord-354833-vvlsqy36 22 14 SwissProt SwissProt NNP cord-354833-vvlsqy36 22 15 or or CC cord-354833-vvlsqy36 22 16 GenBank GenBank NNP cord-354833-vvlsqy36 22 17 , , , cord-354833-vvlsqy36 22 18 rather rather RB cord-354833-vvlsqy36 22 19 than than IN cord-354833-vvlsqy36 22 20 look look VB cord-354833-vvlsqy36 22 21 up up RP cord-354833-vvlsqy36 22 22 these these DT cord-354833-vvlsqy36 22 23 sequences sequence NNS cord-354833-vvlsqy36 22 24 in in IN cord-354833-vvlsqy36 22 25 the the DT cord-354833-vvlsqy36 22 26 primary primary JJ cord-354833-vvlsqy36 22 27 publication publication NN cord-354833-vvlsqy36 22 28 . . . cord-354833-vvlsqy36 23 1 For for IN cord-354833-vvlsqy36 23 2 new new JJ cord-354833-vvlsqy36 23 3 references reference NNS cord-354833-vvlsqy36 23 4 , , , cord-354833-vvlsqy36 23 5 such such JJ cord-354833-vvlsqy36 23 6 information information NN cord-354833-vvlsqy36 23 7 would would MD cord-354833-vvlsqy36 23 8 not not RB cord-354833-vvlsqy36 23 9 even even RB cord-354833-vvlsqy36 23 10 be be VB cord-354833-vvlsqy36 23 11 found find VBN cord-354833-vvlsqy36 23 12 in in IN cord-354833-vvlsqy36 23 13 the the DT cord-354833-vvlsqy36 23 14 primary primary JJ cord-354833-vvlsqy36 23 15 literature literature NN cord-354833-vvlsqy36 23 16 , , , cord-354833-vvlsqy36 23 17 as as IN cord-354833-vvlsqy36 23 18 it -PRON- PRP cord-354833-vvlsqy36 23 19 is be VBZ cord-354833-vvlsqy36 23 20 now now RB cord-354833-vvlsqy36 23 21 mandatory mandatory JJ cord-354833-vvlsqy36 23 22 to to TO cord-354833-vvlsqy36 23 23 deposit deposit VB cord-354833-vvlsqy36 23 24 sequences sequence NNS cord-354833-vvlsqy36 23 25 in in IN cord-354833-vvlsqy36 23 26 a a DT cord-354833-vvlsqy36 23 27 database database NN cord-354833-vvlsqy36 23 28 before before IN cord-354833-vvlsqy36 23 29 publication publication NN cord-354833-vvlsqy36 23 30 . . . cord-354833-vvlsqy36 24 1 Importantly importantly RB cord-354833-vvlsqy36 24 2 , , , cord-354833-vvlsqy36 24 3 these these DT cord-354833-vvlsqy36 24 4 knowledge knowledge NN cord-354833-vvlsqy36 24 5 resources resource NNS cord-354833-vvlsqy36 24 6 can can MD cord-354833-vvlsqy36 24 7 easily easily RB cord-354833-vvlsqy36 24 8 be be VB cord-354833-vvlsqy36 24 9 interlinked interlink VBN cord-354833-vvlsqy36 24 10 , , , cord-354833-vvlsqy36 24 11 making make VBG cord-354833-vvlsqy36 24 12 it -PRON- PRP cord-354833-vvlsqy36 24 13 possible possible JJ cord-354833-vvlsqy36 24 14 to to TO cord-354833-vvlsqy36 24 15 proceed proceed VB cord-354833-vvlsqy36 24 16 from from IN cord-354833-vvlsqy36 24 17 a a DT cord-354833-vvlsqy36 24 18 protein protein NN cord-354833-vvlsqy36 24 19 sequence sequence NN cord-354833-vvlsqy36 24 20 to to IN cord-354833-vvlsqy36 24 21 its -PRON- PRP$ cord-354833-vvlsqy36 24 22 crystal crystal NN cord-354833-vvlsqy36 24 23 structure structure NN cord-354833-vvlsqy36 24 24 , , , cord-354833-vvlsqy36 24 25 to to IN cord-354833-vvlsqy36 24 26 its -PRON- PRP$ cord-354833-vvlsqy36 24 27 related related JJ cord-354833-vvlsqy36 24 28 source source NN cord-354833-vvlsqy36 24 29 organism organism NN cord-354833-vvlsqy36 24 30 and and CC cord-354833-vvlsqy36 24 31 to to IN cord-354833-vvlsqy36 24 32 the the DT cord-354833-vvlsqy36 24 33 literature literature NN cord-354833-vvlsqy36 24 34 references reference NNS cord-354833-vvlsqy36 24 35 that that WDT cord-354833-vvlsqy36 24 36 describe describe VBP cord-354833-vvlsqy36 24 37 it -PRON- PRP cord-354833-vvlsqy36 24 38 . . . cord-354833-vvlsqy36 25 1 With with IN cord-354833-vvlsqy36 25 2 the the DT cord-354833-vvlsqy36 25 3 emergence emergence NN cord-354833-vvlsqy36 25 4 and and CC cord-354833-vvlsqy36 25 5 consolidation consolidation NN cord-354833-vvlsqy36 25 6 of of IN cord-354833-vvlsqy36 25 7 new new JJ cord-354833-vvlsqy36 25 8 databases database NNS cord-354833-vvlsqy36 25 9 , , , cord-354833-vvlsqy36 25 10 this this DT cord-354833-vvlsqy36 25 11 information information NN cord-354833-vvlsqy36 25 12 will will MD cord-354833-vvlsqy36 25 13 expand expand VB cord-354833-vvlsqy36 25 14 to to TO cord-354833-vvlsqy36 25 15 include include VB cord-354833-vvlsqy36 25 16 single single JJ cord-354833-vvlsqy36 25 17 - - HYPH cord-354833-vvlsqy36 25 18 nucleotide nucleotide NN cord-354833-vvlsqy36 25 19 polymorphisms polymorphism NNS cord-354833-vvlsqy36 25 20 ( ( -LRB- cord-354833-vvlsqy36 25 21 SNPs SNPs NNPS cord-354833-vvlsqy36 25 22 ) ) -RRB- cord-354833-vvlsqy36 25 23 , , , cord-354833-vvlsqy36 25 24 biomedical biomedical JJ cord-354833-vvlsqy36 25 25 imaging imaging NN cord-354833-vvlsqy36 25 26 and and CC cord-354833-vvlsqy36 25 27 disease disease NNP cord-354833-vvlsqy36 25 28 association association NNP cord-354833-vvlsqy36 25 29 , , , cord-354833-vvlsqy36 25 30 as as RB cord-354833-vvlsqy36 25 31 well well RB cord-354833-vvlsqy36 25 32 as as IN cord-354833-vvlsqy36 25 33 immune immune JJ cord-354833-vvlsqy36 25 34 epitope epitope NN cord-354833-vvlsqy36 25 35 data datum NNS cord-354833-vvlsqy36 25 36 , , , cord-354833-vvlsqy36 25 37 such such JJ cord-354833-vvlsqy36 25 38 as as IN cord-354833-vvlsqy36 25 39 in in IN cord-354833-vvlsqy36 25 40 the the DT cord-354833-vvlsqy36 25 41 Immune Immune NNP cord-354833-vvlsqy36 25 42 Epitope Epitope NNP cord-354833-vvlsqy36 25 43 Database Database NNP cord-354833-vvlsqy36 25 44 and and CC cord-354833-vvlsqy36 25 45 Analysis Analysis NNP cord-354833-vvlsqy36 25 46 Resource Resource NNP cord-354833-vvlsqy36 25 47 ( ( -LRB- cord-354833-vvlsqy36 25 48 IEDB IEDB NNP cord-354833-vvlsqy36 25 49 ) ) -RRB- cord-354833-vvlsqy36 25 50 , , , cord-354833-vvlsqy36 25 51 which which WDT cord-354833-vvlsqy36 25 52 is be VBZ cord-354833-vvlsqy36 25 53 the the DT cord-354833-vvlsqy36 25 54 focus focus NN cord-354833-vvlsqy36 25 55 of of IN cord-354833-vvlsqy36 25 56 this this DT cord-354833-vvlsqy36 25 57 article article NN cord-354833-vvlsqy36 25 58 . . . cord-354833-vvlsqy36 26 1 Several several JJ cord-354833-vvlsqy36 26 2 databases database NNS cord-354833-vvlsqy36 26 3 devoted devote VBN cord-354833-vvlsqy36 26 4 to to IN cord-354833-vvlsqy36 26 5 immuneepitope immuneepitope NN cord-354833-vvlsqy36 26 6 - - HYPH cord-354833-vvlsqy36 26 7 related relate VBN cord-354833-vvlsqy36 26 8 information information NN cord-354833-vvlsqy36 26 9 have have VBP cord-354833-vvlsqy36 26 10 been be VBN cord-354833-vvlsqy36 26 11 established establish VBN cord-354833-vvlsqy36 26 12 before before IN cord-354833-vvlsqy36 26 13 the the DT cord-354833-vvlsqy36 26 14 recently recently RB cord-354833-vvlsqy36 26 15 developed develop VBN cord-354833-vvlsqy36 26 16 IEDB IEDB NNP cord-354833-vvlsqy36 26 17 , , , cord-354833-vvlsqy36 26 18 such such JJ cord-354833-vvlsqy36 26 19 as as IN cord-354833-vvlsqy36 26 20 SYFPEITHI SYFPEITHI NNP cord-354833-vvlsqy36 26 21 1 1 CD cord-354833-vvlsqy36 26 22 , , , cord-354833-vvlsqy36 26 23 the the DT cord-354833-vvlsqy36 26 24 International International NNP cord-354833-vvlsqy36 26 25 ImMunoGeneTics ImMunoGeneTics NNPS cord-354833-vvlsqy36 26 26 information information NN cord-354833-vvlsqy36 26 27 system system NN cord-354833-vvlsqy36 26 28 ( ( -LRB- cord-354833-vvlsqy36 26 29 IMGT IMGT NNP cord-354833-vvlsqy36 26 30 ) ) -RRB- cord-354833-vvlsqy36 26 31 2 2 CD cord-354833-vvlsqy36 26 32 , , , cord-354833-vvlsqy36 26 33 AntiJen AntiJen NNP cord-354833-vvlsqy36 26 34 3 3 CD cord-354833-vvlsqy36 26 35 , , , cord-354833-vvlsqy36 26 36 ΦΙΜΜ ΦΙΜΜ NNP cord-354833-vvlsqy36 26 37 4 4 CD cord-354833-vvlsqy36 26 38 , , , cord-354833-vvlsqy36 26 39 MHCBN MHCBN NNP cord-354833-vvlsqy36 26 40 5 5 CD cord-354833-vvlsqy36 26 41 and and CC cord-354833-vvlsqy36 26 42 HLA HLA NNP cord-354833-vvlsqy36 26 43 Ligand Ligand NNP cord-354833-vvlsqy36 26 44 Database Database NNP cord-354833-vvlsqy36 26 45 6 6 CD cord-354833-vvlsqy36 26 46 , , , cord-354833-vvlsqy36 26 47 as as RB cord-354833-vvlsqy36 26 48 well well RB cord-354833-vvlsqy36 26 49 as as IN cord-354833-vvlsqy36 26 50 pathogenspecific pathogenspecific NN cord-354833-vvlsqy36 26 51 resources resource NNS cord-354833-vvlsqy36 26 52 , , , cord-354833-vvlsqy36 26 53 such such JJ cord-354833-vvlsqy36 26 54 as as IN cord-354833-vvlsqy36 26 55 the the DT cord-354833-vvlsqy36 26 56 HIV HIV NNP cord-354833-vvlsqy36 26 57 database database NN cord-354833-vvlsqy36 26 58 7 7 CD cord-354833-vvlsqy36 26 59 and and CC cord-354833-vvlsqy36 26 60 the the DT cord-354833-vvlsqy36 26 61 HCV HCV NNP cord-354833-vvlsqy36 26 62 database database NN cord-354833-vvlsqy36 26 63 8 8 CD cord-354833-vvlsqy36 26 64 hosted host VBN cord-354833-vvlsqy36 26 65 at at IN cord-354833-vvlsqy36 26 66 the the DT cord-354833-vvlsqy36 26 67 Los Los NNP cord-354833-vvlsqy36 26 68 Alamos Alamos NNP cord-354833-vvlsqy36 26 69 National National NNP cord-354833-vvlsqy36 26 70 Laboratory Laboratory NNP cord-354833-vvlsqy36 26 71 , , , cord-354833-vvlsqy36 26 72 New New NNP cord-354833-vvlsqy36 26 73 Mexico Mexico NNP cord-354833-vvlsqy36 26 74 , , , cord-354833-vvlsqy36 26 75 USA USA NNP cord-354833-vvlsqy36 26 76 ( ( -LRB- cord-354833-vvlsqy36 26 77 see see VB cord-354833-vvlsqy36 26 78 Further further JJ cord-354833-vvlsqy36 26 79 Information information NN cord-354833-vvlsqy36 26 80 for for IN cord-354833-vvlsqy36 26 81 web web NN cord-354833-vvlsqy36 26 82 sites site NNS cord-354833-vvlsqy36 26 83 ) ) -RRB- cord-354833-vvlsqy36 26 84 . . . cord-354833-vvlsqy36 27 1 Clearly clearly RB cord-354833-vvlsqy36 27 2 , , , cord-354833-vvlsqy36 27 3 the the DT cord-354833-vvlsqy36 27 4 design design NN cord-354833-vvlsqy36 27 5 of of IN cord-354833-vvlsqy36 27 6 the the DT cord-354833-vvlsqy36 27 7 IEDB IEDB NNP cord-354833-vvlsqy36 27 8 9,10 9,10 CD cord-354833-vvlsqy36 27 9 would would MD cord-354833-vvlsqy36 27 10 not not RB cord-354833-vvlsqy36 27 11 have have VB cord-354833-vvlsqy36 27 12 been be VBN cord-354833-vvlsqy36 27 13 possible possible JJ cord-354833-vvlsqy36 27 14 without without IN cord-354833-vvlsqy36 27 15 this this DT cord-354833-vvlsqy36 27 16 pioneering pioneering JJ cord-354833-vvlsqy36 27 17 work work NN cord-354833-vvlsqy36 27 18 of of IN cord-354833-vvlsqy36 27 19 others other NNS cord-354833-vvlsqy36 27 20 . . . cord-354833-vvlsqy36 28 1 The the DT cord-354833-vvlsqy36 28 2 development development NN cord-354833-vvlsqy36 28 3 and and CC cord-354833-vvlsqy36 28 4 application application NN cord-354833-vvlsqy36 28 5 of of IN cord-354833-vvlsqy36 28 6 immuno immuno JJ cord-354833-vvlsqy36 28 7 - - JJ cord-354833-vvlsqy36 28 8 informatic informatic JJ cord-354833-vvlsqy36 28 9 databases database NNS cord-354833-vvlsqy36 28 10 and and CC cord-354833-vvlsqy36 28 11 tools tool NNS cord-354833-vvlsqy36 28 12 continues continue VBZ cord-354833-vvlsqy36 28 13 to to TO cord-354833-vvlsqy36 28 14 be be VB cord-354833-vvlsqy36 28 15 a a DT cord-354833-vvlsqy36 28 16 very very RB cord-354833-vvlsqy36 28 17 active active JJ cord-354833-vvlsqy36 28 18 and and CC cord-354833-vvlsqy36 28 19 exciting exciting JJ cord-354833-vvlsqy36 28 20 field field NN cord-354833-vvlsqy36 28 21 of of IN cord-354833-vvlsqy36 28 22 research research NN cord-354833-vvlsqy36 28 23 , , , cord-354833-vvlsqy36 28 24 as as IN cord-354833-vvlsqy36 28 25 evidenced evidence VBN cord-354833-vvlsqy36 28 26 by by IN cord-354833-vvlsqy36 28 27 two two CD cord-354833-vvlsqy36 28 28 recent recent JJ cord-354833-vvlsqy36 28 29 reviews review NNS cord-354833-vvlsqy36 28 30 of of IN cord-354833-vvlsqy36 28 31 the the DT cord-354833-vvlsqy36 28 32 field field NN cord-354833-vvlsqy36 28 33 11 11 CD cord-354833-vvlsqy36 28 34 , , , cord-354833-vvlsqy36 28 35 12 12 CD cord-354833-vvlsqy36 28 36 . . . cord-354833-vvlsqy36 29 1 Although although IN cord-354833-vvlsqy36 29 2 the the DT cord-354833-vvlsqy36 29 3 focus focus NN cord-354833-vvlsqy36 29 4 of of IN cord-354833-vvlsqy36 29 5 this this DT cord-354833-vvlsqy36 29 6 Innovation Innovation NNP cord-354833-vvlsqy36 29 7 article article NN cord-354833-vvlsqy36 29 8 is be VBZ cord-354833-vvlsqy36 29 9 on on IN cord-354833-vvlsqy36 29 10 the the DT cord-354833-vvlsqy36 29 11 IEDB IEDB NNP cord-354833-vvlsqy36 29 12 , , , cord-354833-vvlsqy36 29 13 we -PRON- PRP cord-354833-vvlsqy36 29 14 want want VBP cord-354833-vvlsqy36 29 15 to to TO cord-354833-vvlsqy36 29 16 acknowledge acknowledge VB cord-354833-vvlsqy36 29 17 that that IN cord-354833-vvlsqy36 29 18 its -PRON- PRP$ cord-354833-vvlsqy36 29 19 success success NN cord-354833-vvlsqy36 29 20 is be VBZ cord-354833-vvlsqy36 29 21 based base VBN cord-354833-vvlsqy36 29 22 and and CC cord-354833-vvlsqy36 29 23 is be VBZ cord-354833-vvlsqy36 29 24 dependent dependent JJ cord-354833-vvlsqy36 29 25 on on IN cord-354833-vvlsqy36 29 26 contributions contribution NNS cord-354833-vvlsqy36 29 27 of of IN cord-354833-vvlsqy36 29 28 a a DT cord-354833-vvlsqy36 29 29 much much RB cord-354833-vvlsqy36 29 30 larger large JJR cord-354833-vvlsqy36 29 31 scientific scientific JJ cord-354833-vvlsqy36 29 32 community community NN cord-354833-vvlsqy36 29 33 . . . cord-354833-vvlsqy36 30 1 The the DT cord-354833-vvlsqy36 30 2 IEDB IEDB NNP cord-354833-vvlsqy36 30 3 is be VBZ cord-354833-vvlsqy36 30 4 part part NN cord-354833-vvlsqy36 30 5 of of IN cord-354833-vvlsqy36 30 6 the the DT cord-354833-vvlsqy36 30 7 National National NNP cord-354833-vvlsqy36 30 8 Institute Institute NNP cord-354833-vvlsqy36 30 9 of of IN cord-354833-vvlsqy36 30 10 Allergy Allergy NNP cord-354833-vvlsqy36 30 11 and and CC cord-354833-vvlsqy36 30 12 Infectious Infectious NNP cord-354833-vvlsqy36 30 13 Diseases Diseases NNPS cord-354833-vvlsqy36 30 14 ( ( -LRB- cord-354833-vvlsqy36 30 15 NIAID NIAID NNP cord-354833-vvlsqy36 30 16 ) ) -RRB- cord-354833-vvlsqy36 30 17 biodefence biodefence NNP cord-354833-vvlsqy36 30 18 programme programme NN cord-354833-vvlsqy36 30 19 . . . cord-354833-vvlsqy36 31 1 The the DT cord-354833-vvlsqy36 31 2 IEDB IEDB NNP cord-354833-vvlsqy36 31 3 is be VBZ cord-354833-vvlsqy36 31 4 designed design VBN cord-354833-vvlsqy36 31 5 to to TO cord-354833-vvlsqy36 31 6 organize organize VB cord-354833-vvlsqy36 31 7 the the DT cord-354833-vvlsqy36 31 8 ever ever RB cord-354833-vvlsqy36 31 9 - - HYPH cord-354833-vvlsqy36 31 10 growing grow VBG cord-354833-vvlsqy36 31 11 body body NN cord-354833-vvlsqy36 31 12 of of IN cord-354833-vvlsqy36 31 13 information information NN cord-354833-vvlsqy36 31 14 related relate VBN cord-354833-vvlsqy36 31 15 to to IN cord-354833-vvlsqy36 31 16 immune immune JJ cord-354833-vvlsqy36 31 17 epitopes epitope NNS cord-354833-vvlsqy36 31 18 that that WDT cord-354833-vvlsqy36 31 19 are be VBP cord-354833-vvlsqy36 31 20 recognized recognize VBN cord-354833-vvlsqy36 31 21 by by IN cord-354833-vvlsqy36 31 22 T T NNP cord-354833-vvlsqy36 31 23 cells cell NNS cord-354833-vvlsqy36 31 24 and and CC cord-354833-vvlsqy36 31 25 antibodies antibody NNS cord-354833-vvlsqy36 31 26 from from IN cord-354833-vvlsqy36 31 27 humans human NNS cord-354833-vvlsqy36 31 28 , , , cord-354833-vvlsqy36 31 29 non non JJ cord-354833-vvlsqy36 31 30 - - JJ cord-354833-vvlsqy36 31 31 human human JJ cord-354833-vvlsqy36 31 32 primates primate NNS cord-354833-vvlsqy36 31 33 and and CC cord-354833-vvlsqy36 31 34 laboratory laboratory NN cord-354833-vvlsqy36 31 35 animals animal NNS cord-354833-vvlsqy36 31 36 . . . cord-354833-vvlsqy36 32 1 The the DT cord-354833-vvlsqy36 32 2 current current JJ cord-354833-vvlsqy36 32 3 focus focus NN cord-354833-vvlsqy36 32 4 of of IN cord-354833-vvlsqy36 32 5 the the DT cord-354833-vvlsqy36 32 6 database database NN cord-354833-vvlsqy36 32 7 is be VBZ cord-354833-vvlsqy36 32 8 on on IN cord-354833-vvlsqy36 32 9 NIAID NIAID NNP cord-354833-vvlsqy36 32 10 Category Category NNP cord-354833-vvlsqy36 32 11 A A NNP cord-354833-vvlsqy36 32 12 , , , cord-354833-vvlsqy36 32 13 B b NN cord-354833-vvlsqy36 32 14 and and CC cord-354833-vvlsqy36 32 15 C C NNP cord-354833-vvlsqy36 32 16 Priority Priority NNP cord-354833-vvlsqy36 32 17 Pathogens Pathogens NNPS cord-354833-vvlsqy36 32 18 13 13 CD cord-354833-vvlsqy36 32 19 , , , cord-354833-vvlsqy36 32 20 which which WDT cord-354833-vvlsqy36 32 21 include include VBP cord-354833-vvlsqy36 32 22 influenza influenza NN cord-354833-vvlsqy36 32 23 A a DT cord-354833-vvlsqy36 32 24 virus virus NN cord-354833-vvlsqy36 32 25 , , , cord-354833-vvlsqy36 32 26 and and CC cord-354833-vvlsqy36 32 27 emerging emerge VBG cord-354833-vvlsqy36 32 28 and and CC cord-354833-vvlsqy36 32 29 re re JJ cord-354833-vvlsqy36 32 30 - - JJ cord-354833-vvlsqy36 32 31 emerging emerge VBG cord-354833-vvlsqy36 32 32 infectious infectious JJ cord-354833-vvlsqy36 32 33 pathogens pathogen NNS cord-354833-vvlsqy36 32 34 , , , cord-354833-vvlsqy36 32 35 such such JJ cord-354833-vvlsqy36 32 36 as as IN cord-354833-vvlsqy36 32 37 Bacillus Bacillus NNP cord-354833-vvlsqy36 32 38 anthracis anthracis NN cord-354833-vvlsqy36 32 39 , , , cord-354833-vvlsqy36 32 40 Ebola Ebola NNP cord-354833-vvlsqy36 32 41 virus virus NN cord-354833-vvlsqy36 32 42 , , , cord-354833-vvlsqy36 32 43 West West NNP cord-354833-vvlsqy36 32 44 Nile Nile NNP cord-354833-vvlsqy36 32 45 virus virus NN cord-354833-vvlsqy36 32 46 , , , cord-354833-vvlsqy36 32 47 Nipah Nipah NNP cord-354833-vvlsqy36 32 48 virus virus NN cord-354833-vvlsqy36 32 49 and and CC cord-354833-vvlsqy36 32 50 severe severe JJ cord-354833-vvlsqy36 32 51 acute acute JJ cord-354833-vvlsqy36 32 52 respiratory respiratory JJ cord-354833-vvlsqy36 32 53 syndrome syndrome NN cord-354833-vvlsqy36 32 54 ( ( -LRB- cord-354833-vvlsqy36 32 55 SARS)-associated sars)-associated CD cord-354833-vvlsqy36 32 56 coronavirus coronavirus NN cord-354833-vvlsqy36 32 57 . . . cord-354833-vvlsqy36 33 1 Epitopes Epitopes NNP cord-354833-vvlsqy36 33 2 from from IN cord-354833-vvlsqy36 33 3 other other JJ cord-354833-vvlsqy36 33 4 infectious infectious JJ cord-354833-vvlsqy36 33 5 pathogens pathogen NNS cord-354833-vvlsqy36 33 6 , , , cord-354833-vvlsqy36 33 7 allergens allergen NNS cord-354833-vvlsqy36 33 8 and and CC cord-354833-vvlsqy36 33 9 those those DT cord-354833-vvlsqy36 33 10 involved involve VBN cord-354833-vvlsqy36 33 11 in in IN cord-354833-vvlsqy36 33 12 autoimmunity autoimmunity NN cord-354833-vvlsqy36 33 13 are be VBP cord-354833-vvlsqy36 33 14 also also RB cord-354833-vvlsqy36 33 15 within within IN cord-354833-vvlsqy36 33 16 the the DT cord-354833-vvlsqy36 33 17 scope scope NN cord-354833-vvlsqy36 33 18 of of IN cord-354833-vvlsqy36 33 19 the the DT cord-354833-vvlsqy36 33 20 IEDB IEDB NNP cord-354833-vvlsqy36 33 21 . . . cord-354833-vvlsqy36 34 1 The the DT cord-354833-vvlsqy36 34 2 users user NNS cord-354833-vvlsqy36 34 3 of of IN cord-354833-vvlsqy36 34 4 the the DT cord-354833-vvlsqy36 34 5 database database NN cord-354833-vvlsqy36 34 6 , , , cord-354833-vvlsqy36 34 7 which which WDT cord-354833-vvlsqy36 34 8 range range VBP cord-354833-vvlsqy36 34 9 from from IN cord-354833-vvlsqy36 34 10 clinicians clinician NNS cord-354833-vvlsqy36 34 11 and and CC cord-354833-vvlsqy36 34 12 vaccinologists vaccinologist NNS cord-354833-vvlsqy36 34 13 to to IN cord-354833-vvlsqy36 34 14 basic basic JJ cord-354833-vvlsqy36 34 15 researchers researcher NNS cord-354833-vvlsqy36 34 16 , , , cord-354833-vvlsqy36 34 17 are be VBP cord-354833-vvlsqy36 34 18 able able JJ cord-354833-vvlsqy36 34 19 to to TO cord-354833-vvlsqy36 34 20 freely freely RB cord-354833-vvlsqy36 34 21 access access VB cord-354833-vvlsqy36 34 22 all all DT cord-354833-vvlsqy36 34 23 of of IN cord-354833-vvlsqy36 34 24 the the DT cord-354833-vvlsqy36 34 25 information information NN cord-354833-vvlsqy36 34 26 related relate VBN cord-354833-vvlsqy36 34 27 to to IN cord-354833-vvlsqy36 34 28 each each DT cord-354833-vvlsqy36 34 29 epitope epitope NN cord-354833-vvlsqy36 34 30 . . . cord-354833-vvlsqy36 35 1 This this DT cord-354833-vvlsqy36 35 2 includes include VBZ cord-354833-vvlsqy36 35 3 not not RB cord-354833-vvlsqy36 35 4 only only RB cord-354833-vvlsqy36 35 5 structural structural JJ cord-354833-vvlsqy36 35 6 information information NN cord-354833-vvlsqy36 35 7 related relate VBN cord-354833-vvlsqy36 35 8 to to IN cord-354833-vvlsqy36 35 9 the the DT cord-354833-vvlsqy36 35 10 chemical chemical JJ cord-354833-vvlsqy36 35 11 nature nature NN cord-354833-vvlsqy36 35 12 of of IN cord-354833-vvlsqy36 35 13 the the DT cord-354833-vvlsqy36 35 14 epitope epitope NN cord-354833-vvlsqy36 35 15 , , , cord-354833-vvlsqy36 35 16 but but CC cord-354833-vvlsqy36 35 17 also also RB cord-354833-vvlsqy36 35 18 taxonomic taxonomic JJ cord-354833-vvlsqy36 35 19 information information NN cord-354833-vvlsqy36 35 20 related relate VBN cord-354833-vvlsqy36 35 21 to to IN cord-354833-vvlsqy36 35 22 the the DT cord-354833-vvlsqy36 35 23 source source NN cord-354833-vvlsqy36 35 24 of of IN cord-354833-vvlsqy36 35 25 the the DT cord-354833-vvlsqy36 35 26 epitope epitope NN cord-354833-vvlsqy36 35 27 and and CC cord-354833-vvlsqy36 35 28 contextual contextual JJ cord-354833-vvlsqy36 35 29 information information NN cord-354833-vvlsqy36 35 30 related relate VBN cord-354833-vvlsqy36 35 31 to to IN cord-354833-vvlsqy36 35 32 the the DT cord-354833-vvlsqy36 35 33 host host NN cord-354833-vvlsqy36 35 34 recognizing recognize VBG cord-354833-vvlsqy36 35 35 the the DT cord-354833-vvlsqy36 35 36 epitope epitope NN cord-354833-vvlsqy36 35 37 , , , cord-354833-vvlsqy36 35 38 the the DT cord-354833-vvlsqy36 35 39 conditions condition NNS cord-354833-vvlsqy36 35 40 associated associate VBN cord-354833-vvlsqy36 35 41 with with IN cord-354833-vvlsqy36 35 42 immunization immunization NN cord-354833-vvlsqy36 35 43 and and CC cord-354833-vvlsqy36 35 44 the the DT cord-354833-vvlsqy36 35 45 type type NN cord-354833-vvlsqy36 35 46 of of IN cord-354833-vvlsqy36 35 47 assay assay NN cord-354833-vvlsqy36 35 48 used use VBN cord-354833-vvlsqy36 35 49 to to TO cord-354833-vvlsqy36 35 50 detect detect VB cord-354833-vvlsqy36 35 51 the the DT cord-354833-vvlsqy36 35 52 responses response NNS cord-354833-vvlsqy36 35 53 . . . cord-354833-vvlsqy36 36 1 This this DT cord-354833-vvlsqy36 36 2 rich rich JJ cord-354833-vvlsqy36 36 3 description description NN cord-354833-vvlsqy36 36 4 of of IN cord-354833-vvlsqy36 36 5 the the DT cord-354833-vvlsqy36 36 6 multiple multiple JJ cord-354833-vvlsqy36 36 7 contexts contexts NN cord-354833-vvlsqy36 36 8 ( ( -LRB- cord-354833-vvlsqy36 36 9 each each DT cord-354833-vvlsqy36 36 10 corresponding correspond VBG cord-354833-vvlsqy36 36 11 to to IN cord-354833-vvlsqy36 36 12 a a DT cord-354833-vvlsqy36 36 13 record record NN cord-354833-vvlsqy36 36 14 ) ) -RRB- cord-354833-vvlsqy36 36 15 in in IN cord-354833-vvlsqy36 36 16 which which WDT cord-354833-vvlsqy36 36 17 each each DT cord-354833-vvlsqy36 36 18 epitope epitope NN cord-354833-vvlsqy36 36 19 was be VBD cord-354833-vvlsqy36 36 20 reported report VBN cord-354833-vvlsqy36 36 21 to to TO cord-354833-vvlsqy36 36 22 be be VB cord-354833-vvlsqy36 36 23 recognized recognize VBN cord-354833-vvlsqy36 36 24 is be VBZ cord-354833-vvlsqy36 36 25 important important JJ cord-354833-vvlsqy36 36 26 because because IN cord-354833-vvlsqy36 36 27 it -PRON- PRP cord-354833-vvlsqy36 36 28 allows allow VBZ cord-354833-vvlsqy36 36 29 the the DT cord-354833-vvlsqy36 36 30 researcher researcher NN cord-354833-vvlsqy36 36 31 to to TO cord-354833-vvlsqy36 36 32 ask ask VB cord-354833-vvlsqy36 36 33 specific specific JJ cord-354833-vvlsqy36 36 34 questions question NNS cord-354833-vvlsqy36 36 35 . . . cord-354833-vvlsqy36 37 1 For for IN cord-354833-vvlsqy36 37 2 example example NN cord-354833-vvlsqy36 37 3 , , , cord-354833-vvlsqy36 37 4 which which WDT cord-354833-vvlsqy36 37 5 T t NN cord-354833-vvlsqy36 37 6 - - HYPH cord-354833-vvlsqy36 37 7 cell cell NN cord-354833-vvlsqy36 37 8 epitopes epitope NNS cord-354833-vvlsqy36 37 9 were be VBD cord-354833-vvlsqy36 37 10 recognized recognize VBN cord-354833-vvlsqy36 37 11 in in IN cord-354833-vvlsqy36 37 12 macaques macaque NNS cord-354833-vvlsqy36 37 13 , , , cord-354833-vvlsqy36 37 14 are be VBP cord-354833-vvlsqy36 37 15 derived derive VBN cord-354833-vvlsqy36 37 16 from from IN cord-354833-vvlsqy36 37 17 SARS SARS NNP cord-354833-vvlsqy36 37 18 and and CC cord-354833-vvlsqy36 37 19 are be VBP cord-354833-vvlsqy36 37 20 associated associate VBN cord-354833-vvlsqy36 37 21 with with IN cord-354833-vvlsqy36 37 22 interferon interferon NN cord-354833-vvlsqy36 37 23 release release NN cord-354833-vvlsqy36 37 24 , , , cord-354833-vvlsqy36 37 25 after after IN cord-354833-vvlsqy36 37 26 recognition recognition NN cord-354833-vvlsqy36 37 27 of of IN cord-354833-vvlsqy36 37 28 infected infected JJ cord-354833-vvlsqy36 37 29 cells cell NNS cord-354833-vvlsqy36 37 30 in in IN cord-354833-vvlsqy36 37 31 vitro vitro FW cord-354833-vvlsqy36 37 32 ? ? . cord-354833-vvlsqy36 38 1 Currently currently RB cord-354833-vvlsqy36 38 2 , , , cord-354833-vvlsqy36 38 3 the the DT cord-354833-vvlsqy36 38 4 IEDB IEDB NNP cord-354833-vvlsqy36 38 5 contains contain VBZ cord-354833-vvlsqy36 38 6 data datum NNS cord-354833-vvlsqy36 38 7 derived derive VBN cord-354833-vvlsqy36 38 8 from from IN cord-354833-vvlsqy36 38 9 over over IN cord-354833-vvlsqy36 38 10 3,200 3,200 CD cord-354833-vvlsqy36 38 11 published publish VBN cord-354833-vvlsqy36 38 12 papers paper NNS cord-354833-vvlsqy36 38 13 , , , cord-354833-vvlsqy36 38 14 relating relate VBG cord-354833-vvlsqy36 38 15 to to IN cord-354833-vvlsqy36 38 16 approximately approximately RB cord-354833-vvlsqy36 38 17 26,000 26,000 CD cord-354833-vvlsqy36 38 18 different different JJ cord-354833-vvlsqy36 38 19 epitopes epitope NNS cord-354833-vvlsqy36 38 20 , , , cord-354833-vvlsqy36 38 21 and and CC cord-354833-vvlsqy36 38 22 approximately approximately RB cord-354833-vvlsqy36 38 23 40 40 CD cord-354833-vvlsqy36 38 24 new new JJ cord-354833-vvlsqy36 38 25 papers paper NNS cord-354833-vvlsqy36 38 26 are be VBP cord-354833-vvlsqy36 38 27 added add VBN cord-354833-vvlsqy36 38 28 weekly weekly RB cord-354833-vvlsqy36 38 29 14 14 CD cord-354833-vvlsqy36 38 30 . . . cord-354833-vvlsqy36 39 1 In in IN cord-354833-vvlsqy36 39 2 addition addition NN cord-354833-vvlsqy36 39 3 to to IN cord-354833-vvlsqy36 39 4 hosting host VBG cord-354833-vvlsqy36 39 5 data datum NNS cord-354833-vvlsqy36 39 6 , , , cord-354833-vvlsqy36 39 7 the the DT cord-354833-vvlsqy36 39 8 IEDB IEDB NNP cord-354833-vvlsqy36 39 9 also also RB cord-354833-vvlsqy36 39 10 hosts host VBZ cord-354833-vvlsqy36 39 11 a a DT cord-354833-vvlsqy36 39 12 collection collection NN cord-354833-vvlsqy36 39 13 of of IN cord-354833-vvlsqy36 39 14 bioinformatics bioinformatics NN cord-354833-vvlsqy36 39 15 tools tool NNS cord-354833-vvlsqy36 39 16 that that WDT cord-354833-vvlsqy36 39 17 can can MD cord-354833-vvlsqy36 39 18 be be VB cord-354833-vvlsqy36 39 19 used use VBN cord-354833-vvlsqy36 39 20 to to TO cord-354833-vvlsqy36 39 21 predict predict VB cord-354833-vvlsqy36 39 22 B b NN cord-354833-vvlsqy36 39 23 - - HYPH cord-354833-vvlsqy36 39 24 cell cell NN cord-354833-vvlsqy36 39 25 and and CC cord-354833-vvlsqy36 39 26 T t NN cord-354833-vvlsqy36 39 27 - - HYPH cord-354833-vvlsqy36 39 28 cell cell NN cord-354833-vvlsqy36 39 29 epitopes epitope NNS cord-354833-vvlsqy36 39 30 and and CC cord-354833-vvlsqy36 39 31 to to TO cord-354833-vvlsqy36 39 32 analyse analyse VB cord-354833-vvlsqy36 39 33 responses response NNS cord-354833-vvlsqy36 39 34 . . . cord-354833-vvlsqy36 40 1 For for IN cord-354833-vvlsqy36 40 2 example example NN cord-354833-vvlsqy36 40 3 , , , cord-354833-vvlsqy36 40 4 the the DT cord-354833-vvlsqy36 40 5 degree degree NN cord-354833-vvlsqy36 40 6 of of IN cord-354833-vvlsqy36 40 7 conservation conservation NN cord-354833-vvlsqy36 40 8 of of IN cord-354833-vvlsqy36 40 9 a a DT cord-354833-vvlsqy36 40 10 given give VBN cord-354833-vvlsqy36 40 11 epitope epitope NN cord-354833-vvlsqy36 40 12 in in IN cord-354833-vvlsqy36 40 13 different different JJ cord-354833-vvlsqy36 40 14 pathogen pathogen NN cord-354833-vvlsqy36 40 15 isolates isolate NNS cord-354833-vvlsqy36 40 16 can can MD cord-354833-vvlsqy36 40 17 be be VB cord-354833-vvlsqy36 40 18 examined examine VBN cord-354833-vvlsqy36 40 19 , , , cord-354833-vvlsqy36 40 20 or or CC cord-354833-vvlsqy36 40 21 the the DT cord-354833-vvlsqy36 40 22 three three CD cord-354833-vvlsqy36 40 23 - - HYPH cord-354833-vvlsqy36 40 24 dimensional dimensional JJ cord-354833-vvlsqy36 40 25 structure structure NN cord-354833-vvlsqy36 40 26 of of IN cord-354833-vvlsqy36 40 27 epitopes epitope NNS cord-354833-vvlsqy36 40 28 in in IN cord-354833-vvlsqy36 40 29 their -PRON- PRP$ cord-354833-vvlsqy36 40 30 native native JJ cord-354833-vvlsqy36 40 31 antigen antigen NN cord-354833-vvlsqy36 40 32 can can MD cord-354833-vvlsqy36 40 33 be be VB cord-354833-vvlsqy36 40 34 visualized visualize VBN cord-354833-vvlsqy36 40 35 . . . cord-354833-vvlsqy36 41 1 In in IN cord-354833-vvlsqy36 41 2 the the DT cord-354833-vvlsqy36 41 3 design design NN cord-354833-vvlsqy36 41 4 and and CC cord-354833-vvlsqy36 41 5 implementation implementation NN cord-354833-vvlsqy36 41 6 of of IN cord-354833-vvlsqy36 41 7 the the DT cord-354833-vvlsqy36 41 8 IEDB IEDB NNP cord-354833-vvlsqy36 41 9 , , , cord-354833-vvlsqy36 41 10 new new JJ cord-354833-vvlsqy36 41 11 problems problem NNS cord-354833-vvlsqy36 41 12 were be VBD cord-354833-vvlsqy36 41 13 encountered encounter VBN cord-354833-vvlsqy36 41 14 and and CC cord-354833-vvlsqy36 41 15 new new JJ cord-354833-vvlsqy36 41 16 solutions solution NNS cord-354833-vvlsqy36 41 17 devised devise VBN cord-354833-vvlsqy36 41 18 . . . cord-354833-vvlsqy36 42 1 This this DT cord-354833-vvlsqy36 42 2 Innovation Innovation NNP cord-354833-vvlsqy36 42 3 article article NN cord-354833-vvlsqy36 42 4 discusses discuss VBZ cord-354833-vvlsqy36 42 5 the the DT cord-354833-vvlsqy36 42 6 background background NN cord-354833-vvlsqy36 42 7 and and CC cord-354833-vvlsqy36 42 8 rationale rationale NN cord-354833-vvlsqy36 42 9 of of IN cord-354833-vvlsqy36 42 10 the the DT cord-354833-vvlsqy36 42 11 development development NN cord-354833-vvlsqy36 42 12 of of IN cord-354833-vvlsqy36 42 13 the the DT cord-354833-vvlsqy36 42 14 IEDB IEDB NNP cord-354833-vvlsqy36 42 15 , , , cord-354833-vvlsqy36 42 16 illustrates illustrate VBZ cord-354833-vvlsqy36 42 17 how how WRB cord-354833-vvlsqy36 42 18 different different JJ cord-354833-vvlsqy36 42 19 disciplines discipline NNS cord-354833-vvlsqy36 42 20 have have VBP cord-354833-vvlsqy36 42 21 come come VBN cord-354833-vvlsqy36 42 22 together together RB cord-354833-vvlsqy36 42 23 in in IN cord-354833-vvlsqy36 42 24 its -PRON- PRP$ cord-354833-vvlsqy36 42 25 design design NN cord-354833-vvlsqy36 42 26 and and CC cord-354833-vvlsqy36 42 27 implementation implementation NN cord-354833-vvlsqy36 42 28 , , , cord-354833-vvlsqy36 42 29 and and CC cord-354833-vvlsqy36 42 30 illustrates illustrate VBZ cord-354833-vvlsqy36 42 31 its -PRON- PRP$ cord-354833-vvlsqy36 42 32 potential potential JJ cord-354833-vvlsqy36 42 33 use use NN cord-354833-vvlsqy36 42 34 for for IN cord-354833-vvlsqy36 42 35 immunological immunological JJ cord-354833-vvlsqy36 42 36 and and CC cord-354833-vvlsqy36 42 37 biological biological JJ cord-354833-vvlsqy36 42 38 scientists scientist NNS cord-354833-vvlsqy36 42 39 . . . cord-354833-vvlsqy36 43 1 The the DT cord-354833-vvlsqy36 43 2 IEDB IEDB NNP cord-354833-vvlsqy36 43 3 is be VBZ cord-354833-vvlsqy36 43 4 the the DT cord-354833-vvlsqy36 43 5 first first JJ cord-354833-vvlsqy36 43 6 epitope epitope NN cord-354833-vvlsqy36 43 7 - - HYPH cord-354833-vvlsqy36 43 8 related relate VBN cord-354833-vvlsqy36 43 9 database database NN cord-354833-vvlsqy36 43 10 that that WDT cord-354833-vvlsqy36 43 11 attempts attempt VBZ cord-354833-vvlsqy36 43 12 to to TO cord-354833-vvlsqy36 43 13 capture capture VB cord-354833-vvlsqy36 43 14 the the DT cord-354833-vvlsqy36 43 15 context context NN cord-354833-vvlsqy36 43 16 of of IN cord-354833-vvlsqy36 43 17 immune immune JJ cord-354833-vvlsqy36 43 18 recognition recognition NN cord-354833-vvlsqy36 43 19 in in IN cord-354833-vvlsqy36 43 20 a a DT cord-354833-vvlsqy36 43 21 detailed detailed JJ cord-354833-vvlsqy36 43 22 , , , cord-354833-vvlsqy36 43 23 searchable searchable JJ cord-354833-vvlsqy36 43 24 way way NN cord-354833-vvlsqy36 43 25 . . . cord-354833-vvlsqy36 44 1 We -PRON- PRP cord-354833-vvlsqy36 44 2 accomplished accomplish VBD cord-354833-vvlsqy36 44 3 this this DT cord-354833-vvlsqy36 44 4 by by IN cord-354833-vvlsqy36 44 5 using use VBG cord-354833-vvlsqy36 44 6 several several JJ cord-354833-vvlsqy36 44 7 hundred hundred CD cord-354833-vvlsqy36 44 8 different different JJ cord-354833-vvlsqy36 44 9 fields field NNS cord-354833-vvlsqy36 44 10 encompassing encompass VBG cord-354833-vvlsqy36 44 11 the the DT cord-354833-vvlsqy36 44 12 database database NN cord-354833-vvlsqy36 44 13 , , , cord-354833-vvlsqy36 44 14 grouped group VBN cord-354833-vvlsqy36 44 15 into into IN cord-354833-vvlsqy36 44 16 several several JJ cord-354833-vvlsqy36 44 17 main main JJ cord-354833-vvlsqy36 44 18 classes class NNS cord-354833-vvlsqy36 44 19 or or CC cord-354833-vvlsqy36 44 20 categories category NNS cord-354833-vvlsqy36 44 21 , , , cord-354833-vvlsqy36 44 22 such such JJ cord-354833-vvlsqy36 44 23 as as IN cord-354833-vvlsqy36 44 24 the the DT cord-354833-vvlsqy36 44 25 literary literary JJ cord-354833-vvlsqy36 44 26 reference reference NN cord-354833-vvlsqy36 44 27 , , , cord-354833-vvlsqy36 44 28 the the DT cord-354833-vvlsqy36 44 29 structure structure NN cord-354833-vvlsqy36 44 30 of of IN cord-354833-vvlsqy36 44 31 the the DT cord-354833-vvlsqy36 44 32 epitope epitope NN cord-354833-vvlsqy36 44 33 , , , cord-354833-vvlsqy36 44 34 the the DT cord-354833-vvlsqy36 44 35 source source NN cord-354833-vvlsqy36 44 36 organism organism NN cord-354833-vvlsqy36 44 37 of of IN cord-354833-vvlsqy36 44 38 the the DT cord-354833-vvlsqy36 44 39 epitope epitope NN cord-354833-vvlsqy36 44 40 and and CC cord-354833-vvlsqy36 44 41 information information NN cord-354833-vvlsqy36 44 42 on on IN cord-354833-vvlsqy36 44 43 the the DT cord-354833-vvlsqy36 44 44 context context NN cord-354833-vvlsqy36 44 45 of of IN cord-354833-vvlsqy36 44 46 epitope epitope NN cord-354833-vvlsqy36 44 47 recognition recognition NN cord-354833-vvlsqy36 44 48 , , , cord-354833-vvlsqy36 44 49 such such JJ cord-354833-vvlsqy36 44 50 as as IN cord-354833-vvlsqy36 44 51 the the DT cord-354833-vvlsqy36 44 52 host host NN cord-354833-vvlsqy36 44 53 species species NN cord-354833-vvlsqy36 44 54 , , , cord-354833-vvlsqy36 44 55 immunization immunization NN cord-354833-vvlsqy36 44 56 strategy strategy NN cord-354833-vvlsqy36 44 57 and and CC cord-354833-vvlsqy36 44 58 the the DT cord-354833-vvlsqy36 44 59 type type NN cord-354833-vvlsqy36 44 60 of of IN cord-354833-vvlsqy36 44 61 assay assay NN cord-354833-vvlsqy36 44 62 used use VBN cord-354833-vvlsqy36 44 63 to to TO cord-354833-vvlsqy36 44 64 detect detect VB cord-354833-vvlsqy36 44 65 a a DT cord-354833-vvlsqy36 44 66 response response NN cord-354833-vvlsqy36 44 67 . . . cord-354833-vvlsqy36 45 1 The the DT cord-354833-vvlsqy36 45 2 complexity complexity NN cord-354833-vvlsqy36 45 3 of of IN cord-354833-vvlsqy36 45 4 the the DT cord-354833-vvlsqy36 45 5 data datum NNS cord-354833-vvlsqy36 45 6 captured capture VBN cord-354833-vvlsqy36 45 7 in in IN cord-354833-vvlsqy36 45 8 the the DT cord-354833-vvlsqy36 45 9 IEDB IEDB NNP cord-354833-vvlsqy36 45 10 makes make VBZ cord-354833-vvlsqy36 45 11 it -PRON- PRP cord-354833-vvlsqy36 45 12 difficult difficult JJ cord-354833-vvlsqy36 45 13 to to TO cord-354833-vvlsqy36 45 14 ensure ensure VB cord-354833-vvlsqy36 45 15 consistent consistent JJ cord-354833-vvlsqy36 45 16 annotation annotation NN cord-354833-vvlsqy36 45 17 of of IN cord-354833-vvlsqy36 45 18 the the DT cord-354833-vvlsqy36 45 19 data datum NNS cord-354833-vvlsqy36 45 20 by by IN cord-354833-vvlsqy36 45 21 curators curator NNS cord-354833-vvlsqy36 45 22 and and CC cord-354833-vvlsqy36 45 23 accurate accurate JJ cord-354833-vvlsqy36 45 24 interpretation interpretation NN cord-354833-vvlsqy36 45 25 of of IN cord-354833-vvlsqy36 45 26 the the DT cord-354833-vvlsqy36 45 27 data datum NNS cord-354833-vvlsqy36 45 28 by by IN cord-354833-vvlsqy36 45 29 users user NNS cord-354833-vvlsqy36 45 30 . . . cord-354833-vvlsqy36 46 1 This this DT cord-354833-vvlsqy36 46 2 common common JJ cord-354833-vvlsqy36 46 3 problem problem NN cord-354833-vvlsqy36 46 4 in in IN cord-354833-vvlsqy36 46 5 developing develop VBG cord-354833-vvlsqy36 46 6 a a DT cord-354833-vvlsqy36 46 7 knowledge knowledge NN cord-354833-vvlsqy36 46 8 resource resource NN cord-354833-vvlsqy36 46 9 is be VBZ cord-354833-vvlsqy36 46 10 addressed address VBN cord-354833-vvlsqy36 46 11 by by IN cord-354833-vvlsqy36 46 12 developing develop VBG cord-354833-vvlsqy36 46 13 a a DT cord-354833-vvlsqy36 46 14 formal formal JJ cord-354833-vvlsqy36 46 15 ontology ontology NN cord-354833-vvlsqy36 46 16 . . . cord-354833-vvlsqy36 47 1 Ontologies ontology NNS cord-354833-vvlsqy36 47 2 provide provide VBP cord-354833-vvlsqy36 47 3 exact exact JJ cord-354833-vvlsqy36 47 4 definitions definition NNS cord-354833-vvlsqy36 47 5 of of IN cord-354833-vvlsqy36 47 6 the the DT cord-354833-vvlsqy36 47 7 terms term NNS cord-354833-vvlsqy36 47 8 used use VBN cord-354833-vvlsqy36 47 9 in in IN cord-354833-vvlsqy36 47 10 annotating annotate VBG cord-354833-vvlsqy36 47 11 the the DT cord-354833-vvlsqy36 47 12 data datum NNS cord-354833-vvlsqy36 47 13 , , , cord-354833-vvlsqy36 47 14 as as RB cord-354833-vvlsqy36 47 15 well well RB cord-354833-vvlsqy36 47 16 as as IN cord-354833-vvlsqy36 47 17 their -PRON- PRP$ cord-354833-vvlsqy36 47 18 relationships relationship NNS cord-354833-vvlsqy36 47 19 , , , cord-354833-vvlsqy36 47 20 and and CC cord-354833-vvlsqy36 47 21 they -PRON- PRP cord-354833-vvlsqy36 47 22 facilitate facilitate VBP cord-354833-vvlsqy36 47 23 the the DT cord-354833-vvlsqy36 47 24 integration integration NN cord-354833-vvlsqy36 47 25 of of IN cord-354833-vvlsqy36 47 26 data datum NNS cord-354833-vvlsqy36 47 27 from from IN cord-354833-vvlsqy36 47 28 different different JJ cord-354833-vvlsqy36 47 29 sources source NNS cord-354833-vvlsqy36 47 30 . . . cord-354833-vvlsqy36 48 1 The the DT cord-354833-vvlsqy36 48 2 recent recent JJ cord-354833-vvlsqy36 48 3 creation creation NN cord-354833-vvlsqy36 48 4 of of IN cord-354833-vvlsqy36 48 5 The the DT cord-354833-vvlsqy36 48 6 National National NNP cord-354833-vvlsqy36 48 7 Center Center NNP cord-354833-vvlsqy36 48 8 for for IN cord-354833-vvlsqy36 48 9 Biomedical Biomedical NNP cord-354833-vvlsqy36 48 10 Ontologies Ontologies NNP cord-354833-vvlsqy36 48 11 15 15 CD cord-354833-vvlsqy36 48 12 will will MD cord-354833-vvlsqy36 48 13 centralize centralize VB cord-354833-vvlsqy36 48 14 and and CC cord-354833-vvlsqy36 48 15 improve improve VB cord-354833-vvlsqy36 48 16 efforts effort NNS cord-354833-vvlsqy36 48 17 in in IN cord-354833-vvlsqy36 48 18 this this DT cord-354833-vvlsqy36 48 19 area area NN cord-354833-vvlsqy36 48 20 . . . cord-354833-vvlsqy36 49 1 It -PRON- PRP cord-354833-vvlsqy36 49 2 is be VBZ cord-354833-vvlsqy36 49 3 difficult difficult JJ cord-354833-vvlsqy36 49 4 to to TO cord-354833-vvlsqy36 49 5 underestimate underestimate VB cord-354833-vvlsqy36 49 6 the the DT cord-354833-vvlsqy36 49 7 importance importance NN cord-354833-vvlsqy36 49 8 of of IN cord-354833-vvlsqy36 49 9 developing develop VBG cord-354833-vvlsqy36 49 10 a a DT cord-354833-vvlsqy36 49 11 formal formal JJ cord-354833-vvlsqy36 49 12 ontology ontology NN cord-354833-vvlsqy36 49 13 for for IN cord-354833-vvlsqy36 49 14 biological biological JJ cord-354833-vvlsqy36 49 15 processes process NNS cord-354833-vvlsqy36 49 16 in in IN cord-354833-vvlsqy36 49 17 general general JJ cord-354833-vvlsqy36 49 18 and and CC cord-354833-vvlsqy36 49 19 , , , cord-354833-vvlsqy36 49 20 in in IN cord-354833-vvlsqy36 49 21 our -PRON- PRP$ cord-354833-vvlsqy36 49 22 case case NN cord-354833-vvlsqy36 49 23 , , , cord-354833-vvlsqy36 49 24 for for IN cord-354833-vvlsqy36 49 25 immune immune JJ cord-354833-vvlsqy36 49 26 epitopes epitope NNS cord-354833-vvlsqy36 49 27 in in IN cord-354833-vvlsqy36 49 28 particular particular JJ cord-354833-vvlsqy36 49 29 . . . cord-354833-vvlsqy36 50 1 Until until IN cord-354833-vvlsqy36 50 2 now now RB cord-354833-vvlsqy36 50 3 , , , cord-354833-vvlsqy36 50 4 formal formal JJ cord-354833-vvlsqy36 50 5 ontologies ontology NNS cord-354833-vvlsqy36 50 6 for for IN cord-354833-vvlsqy36 50 7 host host NN cord-354833-vvlsqy36 50 8 - - HYPH cord-354833-vvlsqy36 50 9 pathogen pathogen NN cord-354833-vvlsqy36 50 10 interactions interaction NNS cord-354833-vvlsqy36 50 11 had have VBD cord-354833-vvlsqy36 50 12 not not RB cord-354833-vvlsqy36 50 13 been be VBN cord-354833-vvlsqy36 50 14 developed develop VBN cord-354833-vvlsqy36 50 15 , , , cord-354833-vvlsqy36 50 16 and and CC cord-354833-vvlsqy36 50 17 accessible accessible JJ cord-354833-vvlsqy36 50 18 formal formal JJ cord-354833-vvlsqy36 50 19 ontologies ontology NNS cord-354833-vvlsqy36 50 20 for for IN cord-354833-vvlsqy36 50 21 immune immune NN cord-354833-vvlsqy36 50 22 - - HYPH cord-354833-vvlsqy36 50 23 based base VBN cord-354833-vvlsqy36 50 24 databases database NNS cord-354833-vvlsqy36 50 25 had have VBD cord-354833-vvlsqy36 50 26 been be VBN cord-354833-vvlsqy36 50 27 limited limit VBN cord-354833-vvlsqy36 50 28 to to IN cord-354833-vvlsqy36 50 29 a a DT cord-354833-vvlsqy36 50 30 few few JJ cord-354833-vvlsqy36 50 31 examples example NNS cord-354833-vvlsqy36 50 32 16 16 CD cord-354833-vvlsqy36 50 33 . . . cord-354833-vvlsqy36 51 1 Developing develop VBG cord-354833-vvlsqy36 51 2 a a DT cord-354833-vvlsqy36 51 3 complete complete JJ cord-354833-vvlsqy36 51 4 ontology ontology NN cord-354833-vvlsqy36 51 5 requires require VBZ cord-354833-vvlsqy36 51 6 exhaustive exhaustive JJ cord-354833-vvlsqy36 51 7 information information NN cord-354833-vvlsqy36 51 8 on on IN cord-354833-vvlsqy36 51 9 the the DT cord-354833-vvlsqy36 51 10 kinds kind NNS cord-354833-vvlsqy36 51 11 of of IN cord-354833-vvlsqy36 51 12 data datum NNS cord-354833-vvlsqy36 51 13 present present JJ cord-354833-vvlsqy36 51 14 in in IN cord-354833-vvlsqy36 51 15 the the DT cord-354833-vvlsqy36 51 16 knowledge knowledge NN cord-354833-vvlsqy36 51 17 domain domain NN cord-354833-vvlsqy36 51 18 . . . cord-354833-vvlsqy36 52 1 The the DT cord-354833-vvlsqy36 52 2 gathering gathering NN cord-354833-vvlsqy36 52 3 of of IN cord-354833-vvlsqy36 52 4 such such JJ cord-354833-vvlsqy36 52 5 data datum NNS cord-354833-vvlsqy36 52 6 must must MD cord-354833-vvlsqy36 52 7 be be VB cord-354833-vvlsqy36 52 8 done do VBN cord-354833-vvlsqy36 52 9 in in IN cord-354833-vvlsqy36 52 10 a a DT cord-354833-vvlsqy36 52 11 formal formal JJ cord-354833-vvlsqy36 52 12 way way NN cord-354833-vvlsqy36 52 13 , , , cord-354833-vvlsqy36 52 14 again again RB cord-354833-vvlsqy36 52 15 requiring require VBG cord-354833-vvlsqy36 52 16 an an DT cord-354833-vvlsqy36 52 17 ontology ontology NN cord-354833-vvlsqy36 52 18 . . . cord-354833-vvlsqy36 53 1 To to TO cord-354833-vvlsqy36 53 2 escape escape VB cord-354833-vvlsqy36 53 3 an an DT cord-354833-vvlsqy36 53 4 infinite infinite JJ cord-354833-vvlsqy36 53 5 loop loop NN cord-354833-vvlsqy36 53 6 , , , cord-354833-vvlsqy36 53 7 it -PRON- PRP cord-354833-vvlsqy36 53 8 is be VBZ cord-354833-vvlsqy36 53 9 necessary necessary JJ cord-354833-vvlsqy36 53 10 to to TO cord-354833-vvlsqy36 53 11 start start VB cord-354833-vvlsqy36 53 12 with with IN cord-354833-vvlsqy36 53 13 an an DT cord-354833-vvlsqy36 53 14 incomplete incomplete JJ cord-354833-vvlsqy36 53 15 ontology ontology NN cord-354833-vvlsqy36 53 16 that that WDT cord-354833-vvlsqy36 53 17 is be VBZ cord-354833-vvlsqy36 53 18 updated update VBN cord-354833-vvlsqy36 53 19 over over IN cord-354833-vvlsqy36 53 20 time time NN cord-354833-vvlsqy36 53 21 as as IN cord-354833-vvlsqy36 53 22 deficiencies deficiency NNS cord-354833-vvlsqy36 53 23 become become VBP cord-354833-vvlsqy36 53 24 apparent apparent JJ cord-354833-vvlsqy36 53 25 as as IN cord-354833-vvlsqy36 53 26 more more JJR cord-354833-vvlsqy36 53 27 data datum NNS cord-354833-vvlsqy36 53 28 are be VBP cord-354833-vvlsqy36 53 29 collected collect VBN cord-354833-vvlsqy36 53 30 . . . cord-354833-vvlsqy36 54 1 This this DT cord-354833-vvlsqy36 54 2 is be VBZ cord-354833-vvlsqy36 54 3 what what WP cord-354833-vvlsqy36 54 4 we -PRON- PRP cord-354833-vvlsqy36 54 5 have have VBP cord-354833-vvlsqy36 54 6 done do VBN cord-354833-vvlsqy36 54 7 by by IN cord-354833-vvlsqy36 54 8 creating create VBG cord-354833-vvlsqy36 54 9 the the DT cord-354833-vvlsqy36 54 10 first first JJ cord-354833-vvlsqy36 54 11 version version NN cord-354833-vvlsqy36 54 12 of of IN cord-354833-vvlsqy36 54 13 an an DT cord-354833-vvlsqy36 54 14 ontology ontology NN cord-354833-vvlsqy36 54 15 of of IN cord-354833-vvlsqy36 54 16 immune immune JJ cord-354833-vvlsqy36 54 17 epitopes epitope NNS cord-354833-vvlsqy36 54 18 17 17 CD cord-354833-vvlsqy36 54 19 , , , cord-354833-vvlsqy36 54 20 which which WDT cord-354833-vvlsqy36 54 21 is be VBZ cord-354833-vvlsqy36 54 22 now now RB cord-354833-vvlsqy36 54 23 progressing progress VBG cord-354833-vvlsqy36 54 24 towards towards IN cord-354833-vvlsqy36 54 25 a a DT cord-354833-vvlsqy36 54 26 more more RBR cord-354833-vvlsqy36 54 27 formal formal JJ cord-354833-vvlsqy36 54 28 ontology ontology NN cord-354833-vvlsqy36 54 29 ( ( -LRB- cord-354833-vvlsqy36 54 30 FIG fig NN cord-354833-vvlsqy36 54 31 . . . cord-354833-vvlsqy36 54 32 1 1 CD cord-354833-vvlsqy36 54 33 ) ) -RRB- cord-354833-vvlsqy36 54 34 . . . cord-354833-vvlsqy36 55 1 This this DT cord-354833-vvlsqy36 55 2 effort effort NN cord-354833-vvlsqy36 55 3 involves involve VBZ cord-354833-vvlsqy36 55 4 the the DT cord-354833-vvlsqy36 55 5 collaboration collaboration NN cord-354833-vvlsqy36 55 6 of of IN cord-354833-vvlsqy36 55 7 a a DT cord-354833-vvlsqy36 55 8 consortium consortium NN cord-354833-vvlsqy36 55 9 of of IN cord-354833-vvlsqy36 55 10 groups group NNS cord-354833-vvlsqy36 55 11 who who WP cord-354833-vvlsqy36 55 12 are be VBP cord-354833-vvlsqy36 55 13 working work VBG cord-354833-vvlsqy36 55 14 towards towards IN cord-354833-vvlsqy36 55 15 the the DT cord-354833-vvlsqy36 55 16 development development NN cord-354833-vvlsqy36 55 17 of of IN cord-354833-vvlsqy36 55 18 an an DT cord-354833-vvlsqy36 55 19 integrated integrated JJ cord-354833-vvlsqy36 55 20 ontology ontology NN cord-354833-vvlsqy36 55 21 for for IN cord-354833-vvlsqy36 55 22 the the DT cord-354833-vvlsqy36 55 23 description description NN cord-354833-vvlsqy36 55 24 of of IN cord-354833-vvlsqy36 55 25 biological biological JJ cord-354833-vvlsqy36 55 26 and and CC cord-354833-vvlsqy36 55 27 medical medical JJ cord-354833-vvlsqy36 55 28 experiments experiment NNS cord-354833-vvlsqy36 55 29 and and CC cord-354833-vvlsqy36 55 30 investigations investigation NNS cord-354833-vvlsqy36 55 31 -the -the ADD cord-354833-vvlsqy36 56 1 Ontology ontology NN cord-354833-vvlsqy36 56 2 for for IN cord-354833-vvlsqy36 56 3 Box Box NNP cord-354833-vvlsqy36 56 4 1 1 CD cord-354833-vvlsqy36 56 5 | | NNS cord-354833-vvlsqy36 57 1 The the DT cord-354833-vvlsqy36 57 2 emerging emerge VBG cord-354833-vvlsqy36 57 3 web web NN cord-354833-vvlsqy36 57 4 of of IN cord-354833-vvlsqy36 57 5 biomedical biomedical JJ cord-354833-vvlsqy36 57 6 knowledge knowledge NN cord-354833-vvlsqy36 57 7 resources resource NNS cord-354833-vvlsqy36 57 8 Listed list VBN cord-354833-vvlsqy36 57 9 here here RB cord-354833-vvlsqy36 57 10 is be VBZ cord-354833-vvlsqy36 57 11 a a DT cord-354833-vvlsqy36 57 12 representative representative JJ cord-354833-vvlsqy36 57 13 selection selection NN cord-354833-vvlsqy36 57 14 of of IN cord-354833-vvlsqy36 57 15 freely freely RB cord-354833-vvlsqy36 57 16 and and CC cord-354833-vvlsqy36 57 17 publicly publicly RB cord-354833-vvlsqy36 57 18 available available JJ cord-354833-vvlsqy36 57 19 resources resource NNS cord-354833-vvlsqy36 57 20 of of IN cord-354833-vvlsqy36 57 21 biomedical biomedical JJ cord-354833-vvlsqy36 57 22 knowledge knowledge NN cord-354833-vvlsqy36 57 23 . . . cord-354833-vvlsqy36 58 1 • • NNP cord-354833-vvlsqy36 59 1 SwissProt SwissProt NNP cord-354833-vvlsqy36 59 2 ( ( -LRB- cord-354833-vvlsqy36 59 3 http://www.expasy.org/sprot/ http://www.expasy.org/sprot/ NNP cord-354833-vvlsqy36 59 4 ) ) -RRB- cord-354833-vvlsqy36 59 5 is be VBZ cord-354833-vvlsqy36 59 6 the the DT cord-354833-vvlsqy36 59 7 manually manually RB cord-354833-vvlsqy36 59 8 curated curate VBN cord-354833-vvlsqy36 59 9 section section NN cord-354833-vvlsqy36 59 10 of of IN cord-354833-vvlsqy36 59 11 the the DT cord-354833-vvlsqy36 59 12 UniProt UniProt NNP cord-354833-vvlsqy36 59 13 Knowledgebase Knowledgebase NNP cord-354833-vvlsqy36 59 14 . . . cord-354833-vvlsqy36 60 1 It -PRON- PRP cord-354833-vvlsqy36 60 2 contains contain VBZ cord-354833-vvlsqy36 60 3 protein protein NN cord-354833-vvlsqy36 60 4 sequences sequence NNS cord-354833-vvlsqy36 60 5 with with IN cord-354833-vvlsqy36 60 6 a a DT cord-354833-vvlsqy36 60 7 high high JJ cord-354833-vvlsqy36 60 8 level level NN cord-354833-vvlsqy36 60 9 of of IN cord-354833-vvlsqy36 60 10 annotation annotation NN cord-354833-vvlsqy36 60 11 ( ( -LRB- cord-354833-vvlsqy36 60 12 such such JJ cord-354833-vvlsqy36 60 13 as as IN cord-354833-vvlsqy36 60 14 the the DT cord-354833-vvlsqy36 60 15 description description NN cord-354833-vvlsqy36 60 16 of of IN cord-354833-vvlsqy36 60 17 the the DT cord-354833-vvlsqy36 60 18 function function NN cord-354833-vvlsqy36 60 19 of of IN cord-354833-vvlsqy36 60 20 a a DT cord-354833-vvlsqy36 60 21 protein protein NN cord-354833-vvlsqy36 60 22 , , , cord-354833-vvlsqy36 60 23 its -PRON- PRP$ cord-354833-vvlsqy36 60 24 domains domain NNS cord-354833-vvlsqy36 60 25 structure structure NN cord-354833-vvlsqy36 60 26 , , , cord-354833-vvlsqy36 60 27 post post JJ cord-354833-vvlsqy36 60 28 - - JJ cord-354833-vvlsqy36 60 29 translational translational JJ cord-354833-vvlsqy36 60 30 modifications modification NNS cord-354833-vvlsqy36 60 31 and and CC cord-354833-vvlsqy36 60 32 variants variant NNS cord-354833-vvlsqy36 60 33 ) ) -RRB- cord-354833-vvlsqy36 60 34 and and CC cord-354833-vvlsqy36 60 35 a a DT cord-354833-vvlsqy36 60 36 minimal minimal JJ cord-354833-vvlsqy36 60 37 level level NN cord-354833-vvlsqy36 60 38 of of IN cord-354833-vvlsqy36 60 39 redundancy redundancy NN cord-354833-vvlsqy36 60 40 . . . cord-354833-vvlsqy36 61 1 • • NNP cord-354833-vvlsqy36 62 1 The the DT cord-354833-vvlsqy36 62 2 RCSB RCSB NNP cord-354833-vvlsqy36 62 3 PDB PDB NNP cord-354833-vvlsqy36 62 4 ( ( -LRB- cord-354833-vvlsqy36 62 5 http://www.rcsb.org/pdb/ http://www.rcsb.org/pdb/ NFP cord-354833-vvlsqy36 62 6 ) ) -RRB- cord-354833-vvlsqy36 62 7 is be VBZ cord-354833-vvlsqy36 62 8 one one CD cord-354833-vvlsqy36 62 9 of of IN cord-354833-vvlsqy36 62 10 several several JJ cord-354833-vvlsqy36 62 11 organizations organization NNS cord-354833-vvlsqy36 62 12 that that WDT cord-354833-vvlsqy36 62 13 act act VBP cord-354833-vvlsqy36 62 14 as as IN cord-354833-vvlsqy36 62 15 deposition deposition NN cord-354833-vvlsqy36 62 16 , , , cord-354833-vvlsqy36 62 17 data data NN cord-354833-vvlsqy36 62 18 processing processing NN cord-354833-vvlsqy36 62 19 and and CC cord-354833-vvlsqy36 62 20 distribution distribution NN cord-354833-vvlsqy36 62 21 centres centre NNS cord-354833-vvlsqy36 62 22 . . . cord-354833-vvlsqy36 63 1 It -PRON- PRP cord-354833-vvlsqy36 63 2 maintains maintain VBZ cord-354833-vvlsqy36 63 3 an an DT cord-354833-vvlsqy36 63 4 archive archive NN cord-354833-vvlsqy36 63 5 of of IN cord-354833-vvlsqy36 63 6 macromolecular macromolecular JJ cord-354833-vvlsqy36 63 7 structural structural JJ cord-354833-vvlsqy36 63 8 data datum NNS cord-354833-vvlsqy36 63 9 as as IN cord-354833-vvlsqy36 63 10 part part NN cord-354833-vvlsqy36 63 11 of of IN cord-354833-vvlsqy36 63 12 the the DT cord-354833-vvlsqy36 63 13 Worldwide Worldwide NNP cord-354833-vvlsqy36 63 14 Protein Protein NNP cord-354833-vvlsqy36 63 15 Data Data NNP cord-354833-vvlsqy36 63 16 Bank Bank NNP cord-354833-vvlsqy36 63 17 ( ( -LRB- cord-354833-vvlsqy36 63 18 wwPDB wwpdb NN cord-354833-vvlsqy36 63 19 at at IN cord-354833-vvlsqy36 63 20 http://www.wwpdb.org/ http://www.wwpdb.org/ ADD cord-354833-vvlsqy36 63 21 ) ) -RRB- cord-354833-vvlsqy36 63 22 . . . cord-354833-vvlsqy36 64 1 • • NNP cord-354833-vvlsqy36 65 1 PubMed PubMed NNP cord-354833-vvlsqy36 65 2 ( ( -LRB- cord-354833-vvlsqy36 65 3 http://www.pubmed.org http://www.pubmed.org NFP cord-354833-vvlsqy36 65 4 ) ) -RRB- cord-354833-vvlsqy36 65 5 is be VBZ cord-354833-vvlsqy36 65 6 a a DT cord-354833-vvlsqy36 65 7 service service NN cord-354833-vvlsqy36 65 8 of of IN cord-354833-vvlsqy36 65 9 the the DT cord-354833-vvlsqy36 65 10 US US NNP cord-354833-vvlsqy36 65 11 National National NNP cord-354833-vvlsqy36 65 12 Library Library NNP cord-354833-vvlsqy36 65 13 of of IN cord-354833-vvlsqy36 65 14 Medicine Medicine NNP cord-354833-vvlsqy36 65 15 that that WDT cord-354833-vvlsqy36 65 16 includes include VBZ cord-354833-vvlsqy36 65 17 abstracts abstract NNS cord-354833-vvlsqy36 65 18 and and CC cord-354833-vvlsqy36 65 19 citations citation NNS cord-354833-vvlsqy36 65 20 from from IN cord-354833-vvlsqy36 65 21 MEDLINE MEDLINE NNP cord-354833-vvlsqy36 65 22 and and CC cord-354833-vvlsqy36 65 23 other other JJ cord-354833-vvlsqy36 65 24 life life NN cord-354833-vvlsqy36 65 25 science science NN cord-354833-vvlsqy36 65 26 journals journal NNS cord-354833-vvlsqy36 65 27 for for IN cord-354833-vvlsqy36 65 28 biomedical biomedical JJ cord-354833-vvlsqy36 65 29 articles article NNS cord-354833-vvlsqy36 65 30 dating date VBG cord-354833-vvlsqy36 65 31 back back RB cord-354833-vvlsqy36 65 32 to to IN cord-354833-vvlsqy36 65 33 the the DT cord-354833-vvlsqy36 65 34 1950s 1950 NNS cord-354833-vvlsqy36 65 35 , , , cord-354833-vvlsqy36 65 36 as as RB cord-354833-vvlsqy36 65 37 well well RB cord-354833-vvlsqy36 65 38 as as IN cord-354833-vvlsqy36 65 39 links link NNS cord-354833-vvlsqy36 65 40 to to IN cord-354833-vvlsqy36 65 41 full full JJ cord-354833-vvlsqy36 65 42 text text NN cord-354833-vvlsqy36 65 43 articles article NNS cord-354833-vvlsqy36 65 44 . . . cord-354833-vvlsqy36 66 1 • • NNP cord-354833-vvlsqy36 67 1 The the DT cord-354833-vvlsqy36 67 2 NCBI NCBI NNP cord-354833-vvlsqy36 67 3 taxonomy taxonomy NN cord-354833-vvlsqy36 67 4 ( ( -LRB- cord-354833-vvlsqy36 67 5 http://www.ncbi.nlm.nih.gov/Taxonomy/ http://www.ncbi.nlm.nih.gov/taxonomy/ ADD cord-354833-vvlsqy36 67 6 ) ) -RRB- cord-354833-vvlsqy36 67 7 contains contain VBZ cord-354833-vvlsqy36 67 8 the the DT cord-354833-vvlsqy36 67 9 names name NNS cord-354833-vvlsqy36 67 10 of of IN cord-354833-vvlsqy36 67 11 all all DT cord-354833-vvlsqy36 67 12 organisms organism NNS cord-354833-vvlsqy36 67 13 that that WDT cord-354833-vvlsqy36 67 14 are be VBP cord-354833-vvlsqy36 67 15 represented represent VBN cord-354833-vvlsqy36 67 16 in in IN cord-354833-vvlsqy36 67 17 genetic genetic JJ cord-354833-vvlsqy36 67 18 databases database NNS cord-354833-vvlsqy36 67 19 with with IN cord-354833-vvlsqy36 67 20 at at RB cord-354833-vvlsqy36 67 21 least least RBS cord-354833-vvlsqy36 67 22 one one CD cord-354833-vvlsqy36 67 23 nucleotide nucleotide NN cord-354833-vvlsqy36 67 24 or or CC cord-354833-vvlsqy36 67 25 protein protein NN cord-354833-vvlsqy36 67 26 sequence sequence NN cord-354833-vvlsqy36 67 27 , , , cord-354833-vvlsqy36 67 28 placed place VBN cord-354833-vvlsqy36 67 29 in in IN cord-354833-vvlsqy36 67 30 a a DT cord-354833-vvlsqy36 67 31 taxonomic taxonomic JJ cord-354833-vvlsqy36 67 32 tree tree NN cord-354833-vvlsqy36 67 33 . . . cord-354833-vvlsqy36 68 1 • • NNP cord-354833-vvlsqy36 69 1 Gene Gene NNP cord-354833-vvlsqy36 69 2 Ontology Ontology NNP cord-354833-vvlsqy36 69 3 ( ( -LRB- cord-354833-vvlsqy36 69 4 http://www.geneontology.org/ http://www.geneontology.org/ ADD cord-354833-vvlsqy36 69 5 ) ) -RRB- cord-354833-vvlsqy36 69 6 provides provide VBZ cord-354833-vvlsqy36 69 7 a a DT cord-354833-vvlsqy36 69 8 controlled control VBN cord-354833-vvlsqy36 69 9 vocabulary vocabulary NN cord-354833-vvlsqy36 69 10 to to TO cord-354833-vvlsqy36 69 11 describe describe VB cord-354833-vvlsqy36 69 12 gene gene NN cord-354833-vvlsqy36 69 13 and and CC cord-354833-vvlsqy36 69 14 gene gene NN cord-354833-vvlsqy36 69 15 - - HYPH cord-354833-vvlsqy36 69 16 product product NN cord-354833-vvlsqy36 69 17 attributes attribute NNS cord-354833-vvlsqy36 69 18 in in IN cord-354833-vvlsqy36 69 19 terms term NNS cord-354833-vvlsqy36 69 20 of of IN cord-354833-vvlsqy36 69 21 their -PRON- PRP$ cord-354833-vvlsqy36 69 22 location location NN cord-354833-vvlsqy36 69 23 in in IN cord-354833-vvlsqy36 69 24 cellular cellular JJ cord-354833-vvlsqy36 69 25 components component NNS cord-354833-vvlsqy36 69 26 , , , cord-354833-vvlsqy36 69 27 their -PRON- PRP$ cord-354833-vvlsqy36 69 28 participation participation NN cord-354833-vvlsqy36 69 29 in in IN cord-354833-vvlsqy36 69 30 biological biological JJ cord-354833-vvlsqy36 69 31 processes process NNS cord-354833-vvlsqy36 69 32 and and CC cord-354833-vvlsqy36 69 33 their -PRON- PRP$ cord-354833-vvlsqy36 69 34 specific specific JJ cord-354833-vvlsqy36 69 35 molecular molecular JJ cord-354833-vvlsqy36 69 36 function function NN cord-354833-vvlsqy36 69 37 . . . cord-354833-vvlsqy36 70 1 18 18 CD cord-354833-vvlsqy36 70 2 ) ) -RRB- cord-354833-vvlsqy36 70 3 . . . cord-354833-vvlsqy36 71 1 In in IN cord-354833-vvlsqy36 71 2 addition addition NN cord-354833-vvlsqy36 71 3 , , , cord-354833-vvlsqy36 71 4 we -PRON- PRP cord-354833-vvlsqy36 71 5 have have VBP cord-354833-vvlsqy36 71 6 contributed contribute VBN cord-354833-vvlsqy36 71 7 to to IN cord-354833-vvlsqy36 71 8 , , , cord-354833-vvlsqy36 71 9 and and CC cord-354833-vvlsqy36 71 10 benefited benefit VBD cord-354833-vvlsqy36 71 11 from from IN cord-354833-vvlsqy36 71 12 , , , cord-354833-vvlsqy36 71 13 a a DT cord-354833-vvlsqy36 71 14 large large JJ cord-354833-vvlsqy36 71 15 - - HYPH cord-354833-vvlsqy36 71 16 scale scale NN cord-354833-vvlsqy36 71 17 revision revision NN cord-354833-vvlsqy36 71 18 of of IN cord-354833-vvlsqy36 71 19 immunology immunology NN cord-354833-vvlsqy36 71 20 - - HYPH cord-354833-vvlsqy36 71 21 related relate VBN cord-354833-vvlsqy36 71 22 terms term NNS cord-354833-vvlsqy36 71 23 in in IN cord-354833-vvlsqy36 71 24 the the DT cord-354833-vvlsqy36 71 25 Gene Gene NNP cord-354833-vvlsqy36 71 26 Ontology Ontology NNP cord-354833-vvlsqy36 71 27 database database NN cord-354833-vvlsqy36 71 28 19 19 CD cord-354833-vvlsqy36 71 29 , , , cord-354833-vvlsqy36 71 30 20 20 CD cord-354833-vvlsqy36 71 31 . . . cord-354833-vvlsqy36 72 1 Collaboration collaboration NN cord-354833-vvlsqy36 72 2 in in IN cord-354833-vvlsqy36 72 3 ontology ontology NN cord-354833-vvlsqy36 72 4 development development NN cord-354833-vvlsqy36 72 5 between between IN cord-354833-vvlsqy36 72 6 different different JJ cord-354833-vvlsqy36 72 7 scientific scientific JJ cord-354833-vvlsqy36 72 8 communities community NNS cord-354833-vvlsqy36 72 9 is be VBZ cord-354833-vvlsqy36 72 10 the the DT cord-354833-vvlsqy36 72 11 key key NN cord-354833-vvlsqy36 72 12 to to TO cord-354833-vvlsqy36 72 13 integrate integrate VB cord-354833-vvlsqy36 72 14 different different JJ cord-354833-vvlsqy36 72 15 biomedical biomedical JJ cord-354833-vvlsqy36 72 16 knowledge knowledge NN cord-354833-vvlsqy36 72 17 resources resource NNS cord-354833-vvlsqy36 72 18 . . . cord-354833-vvlsqy36 73 1 Different different JJ cord-354833-vvlsqy36 73 2 scientific scientific JJ cord-354833-vvlsqy36 73 3 communities community NNS cord-354833-vvlsqy36 73 4 often often RB cord-354833-vvlsqy36 73 5 use use VBP cord-354833-vvlsqy36 73 6 the the DT cord-354833-vvlsqy36 73 7 same same JJ cord-354833-vvlsqy36 73 8 term term NN cord-354833-vvlsqy36 73 9 for for IN cord-354833-vvlsqy36 73 10 different different JJ cord-354833-vvlsqy36 73 11 purposes purpose NNS cord-354833-vvlsqy36 73 12 , , , cord-354833-vvlsqy36 73 13 or or CC cord-354833-vvlsqy36 73 14 different different JJ cord-354833-vvlsqy36 73 15 terms term NNS cord-354833-vvlsqy36 73 16 for for IN cord-354833-vvlsqy36 73 17 the the DT cord-354833-vvlsqy36 73 18 same same JJ cord-354833-vvlsqy36 73 19 concept concept NN cord-354833-vvlsqy36 73 20 , , , cord-354833-vvlsqy36 73 21 so so IN cord-354833-vvlsqy36 73 22 that that IN cord-354833-vvlsqy36 73 23 development development NN cord-354833-vvlsqy36 73 24 of of IN cord-354833-vvlsqy36 73 25 an an DT cord-354833-vvlsqy36 73 26 ontology ontology NN cord-354833-vvlsqy36 73 27 is be VBZ cord-354833-vvlsqy36 73 28 necessary necessary JJ cord-354833-vvlsqy36 73 29 to to TO cord-354833-vvlsqy36 73 30 ensure ensure VB cord-354833-vvlsqy36 73 31 that that IN cord-354833-vvlsqy36 73 32 a a DT cord-354833-vvlsqy36 73 33 given give VBN cord-354833-vvlsqy36 73 34 term term NN cord-354833-vvlsqy36 73 35 has have VBZ cord-354833-vvlsqy36 73 36 the the DT cord-354833-vvlsqy36 73 37 same same JJ cord-354833-vvlsqy36 73 38 meaning meaning NN cord-354833-vvlsqy36 73 39 and and CC cord-354833-vvlsqy36 73 40 associated associated JJ cord-354833-vvlsqy36 73 41 attributes attribute NNS cord-354833-vvlsqy36 73 42 in in IN cord-354833-vvlsqy36 73 43 all all DT cord-354833-vvlsqy36 73 44 databases database NNS cord-354833-vvlsqy36 73 45 that that WDT cord-354833-vvlsqy36 73 46 use use VBP cord-354833-vvlsqy36 73 47 it -PRON- PRP cord-354833-vvlsqy36 73 48 , , , cord-354833-vvlsqy36 73 49 so so IN cord-354833-vvlsqy36 73 50 that that IN cord-354833-vvlsqy36 73 51 researchers researcher NNS cord-354833-vvlsqy36 73 52 can can MD cord-354833-vvlsqy36 73 53 navigate navigate VB cord-354833-vvlsqy36 73 54 the the DT cord-354833-vvlsqy36 73 55 already already RB cord-354833-vvlsqy36 73 56 immense immense JJ cord-354833-vvlsqy36 73 57 and and CC cord-354833-vvlsqy36 73 58 ever ever RB cord-354833-vvlsqy36 73 59 - - HYPH cord-354833-vvlsqy36 73 60 growing grow VBG cord-354833-vvlsqy36 73 61 body body NN cord-354833-vvlsqy36 73 62 of of IN cord-354833-vvlsqy36 73 63 biological biological JJ cord-354833-vvlsqy36 73 64 data datum NNS cord-354833-vvlsqy36 73 65 with with IN cord-354833-vvlsqy36 73 66 confidence confidence NN cord-354833-vvlsqy36 73 67 , , , cord-354833-vvlsqy36 73 68 accuracy accuracy NN cord-354833-vvlsqy36 73 69 and and CC cord-354833-vvlsqy36 73 70 ease ease NN cord-354833-vvlsqy36 73 71 . . . cord-354833-vvlsqy36 74 1 Automating automate VBG cord-354833-vvlsqy36 74 2 the the DT cord-354833-vvlsqy36 74 3 extraction extraction NN cord-354833-vvlsqy36 74 4 of of IN cord-354833-vvlsqy36 74 5 data datum NNS cord-354833-vvlsqy36 74 6 Text Text NNP cord-354833-vvlsqy36 74 7 mining mining NN cord-354833-vvlsqy36 74 8 21 21 CD cord-354833-vvlsqy36 74 9 might might NN cord-354833-vvlsqy36 74 10 at at IN cord-354833-vvlsqy36 74 11 first first RB cord-354833-vvlsqy36 74 12 seem seem VB cord-354833-vvlsqy36 74 13 to to TO cord-354833-vvlsqy36 74 14 be be VB cord-354833-vvlsqy36 74 15 an an DT cord-354833-vvlsqy36 74 16 improbable improbable JJ cord-354833-vvlsqy36 74 17 ally ally NN cord-354833-vvlsqy36 74 18 for for IN cord-354833-vvlsqy36 74 19 the the DT cord-354833-vvlsqy36 74 20 bench bench NN cord-354833-vvlsqy36 74 21 immunologist immunologist NN cord-354833-vvlsqy36 74 22 . . . cord-354833-vvlsqy36 75 1 Nevertheless nevertheless RB cord-354833-vvlsqy36 75 2 , , , cord-354833-vvlsqy36 75 3 we -PRON- PRP cord-354833-vvlsqy36 75 4 believe believe VBP cord-354833-vvlsqy36 75 5 that that IN cord-354833-vvlsqy36 75 6 this this DT cord-354833-vvlsqy36 75 7 field field NN cord-354833-vvlsqy36 75 8 will will MD cord-354833-vvlsqy36 75 9 have have VB cord-354833-vvlsqy36 75 10 a a DT cord-354833-vvlsqy36 75 11 dramatic dramatic JJ cord-354833-vvlsqy36 75 12 impact impact NN cord-354833-vvlsqy36 75 13 in in IN cord-354833-vvlsqy36 75 14 immunobioinformatics immunobioinformatic NNS cord-354833-vvlsqy36 75 15 and and CC cord-354833-vvlsqy36 75 16 systems system NNS cord-354833-vvlsqy36 75 17 biology biology NNP cord-354833-vvlsqy36 75 18 22 22 CD cord-354833-vvlsqy36 75 19 . . . cord-354833-vvlsqy36 76 1 The the DT cord-354833-vvlsqy36 76 2 field field NN cord-354833-vvlsqy36 76 3 originates originate VBZ cord-354833-vvlsqy36 76 4 from from IN cord-354833-vvlsqy36 76 5 the the DT cord-354833-vvlsqy36 76 6 need need NN cord-354833-vvlsqy36 76 7 to to TO cord-354833-vvlsqy36 76 8 automate automate VB cord-354833-vvlsqy36 76 9 the the DT cord-354833-vvlsqy36 76 10 extraction extraction NN cord-354833-vvlsqy36 76 11 of of IN cord-354833-vvlsqy36 76 12 meaning meaning NN cord-354833-vvlsqy36 76 13 from from IN cord-354833-vvlsqy36 76 14 massive massive JJ cord-354833-vvlsqy36 76 15 amounts amount NNS cord-354833-vvlsqy36 76 16 of of IN cord-354833-vvlsqy36 76 17 text text NN cord-354833-vvlsqy36 76 18 . . . cord-354833-vvlsqy36 77 1 Several several JJ cord-354833-vvlsqy36 77 2 of of IN cord-354833-vvlsqy36 77 3 the the DT cord-354833-vvlsqy36 77 4 pioneering pioneering JJ cord-354833-vvlsqy36 77 5 data data NN cord-354833-vvlsqy36 77 6 - - HYPH cord-354833-vvlsqy36 77 7 mining mining NN cord-354833-vvlsqy36 77 8 applications application NNS cord-354833-vvlsqy36 77 9 were be VBD cord-354833-vvlsqy36 77 10 developed develop VBN cord-354833-vvlsqy36 77 11 for for IN cord-354833-vvlsqy36 77 12 non non JJ cord-354833-vvlsqy36 77 13 - - JJ cord-354833-vvlsqy36 77 14 biological biological JJ cord-354833-vvlsqy36 77 15 purposes purpose NNS cord-354833-vvlsqy36 77 16 , , , cord-354833-vvlsqy36 77 17 such such JJ cord-354833-vvlsqy36 77 18 as as IN cord-354833-vvlsqy36 77 19 security security NN cord-354833-vvlsqy36 77 20 projects project NNS cord-354833-vvlsqy36 77 21 sponsored sponsor VBN cord-354833-vvlsqy36 77 22 by by IN cord-354833-vvlsqy36 77 23 various various JJ cord-354833-vvlsqy36 77 24 intelligence intelligence NN cord-354833-vvlsqy36 77 25 agencies agency NNS cord-354833-vvlsqy36 77 26 , , , cord-354833-vvlsqy36 77 27 and and CC cord-354833-vvlsqy36 77 28 for for IN cord-354833-vvlsqy36 77 29 the the DT cord-354833-vvlsqy36 77 30 purpose purpose NN cord-354833-vvlsqy36 77 31 of of IN cord-354833-vvlsqy36 77 32 mining mining NN cord-354833-vvlsqy36 77 33 data datum NNS cord-354833-vvlsqy36 77 34 in in IN cord-354833-vvlsqy36 77 35 patent patent NN cord-354833-vvlsqy36 77 36 applications application NNS cord-354833-vvlsqy36 77 37 . . . cord-354833-vvlsqy36 78 1 Over over IN cord-354833-vvlsqy36 78 2 the the DT cord-354833-vvlsqy36 78 3 years year NNS cord-354833-vvlsqy36 78 4 the the DT cord-354833-vvlsqy36 78 5 field field NN cord-354833-vvlsqy36 78 6 has have VBZ cord-354833-vvlsqy36 78 7 become become VBN cord-354833-vvlsqy36 78 8 increasingly increasingly RB cord-354833-vvlsqy36 78 9 sophisticated sophisticated JJ cord-354833-vvlsqy36 78 10 . . . cord-354833-vvlsqy36 79 1 The the DT cord-354833-vvlsqy36 79 2 basic basic JJ cord-354833-vvlsqy36 79 3 premise premise NN cord-354833-vvlsqy36 79 4 is be VBZ cord-354833-vvlsqy36 79 5 that that DT cord-354833-vvlsqy36 79 6 of of IN cord-354833-vvlsqy36 79 7 a a DT cord-354833-vvlsqy36 79 8 program program NN cord-354833-vvlsqy36 79 9 that that WDT cord-354833-vvlsqy36 79 10 scans scan VBZ cord-354833-vvlsqy36 79 11 through through IN cord-354833-vvlsqy36 79 12 text text NN cord-354833-vvlsqy36 79 13 and and CC cord-354833-vvlsqy36 79 14 extracts extract VBZ cord-354833-vvlsqy36 79 15 data datum NNS cord-354833-vvlsqy36 79 16 in in IN cord-354833-vvlsqy36 79 17 a a DT cord-354833-vvlsqy36 79 18 defined define VBN cord-354833-vvlsqy36 79 19 form form NN cord-354833-vvlsqy36 79 20 ( ( -LRB- cord-354833-vvlsqy36 79 21 that that RB cord-354833-vvlsqy36 79 22 is is RB cord-354833-vvlsqy36 79 23 , , , cord-354833-vvlsqy36 79 24 a a DT cord-354833-vvlsqy36 79 25 format format NN cord-354833-vvlsqy36 79 26 that that WDT cord-354833-vvlsqy36 79 27 can can MD cord-354833-vvlsqy36 79 28 be be VB cord-354833-vvlsqy36 79 29 recognized recognize VBN cord-354833-vvlsqy36 79 30 by by IN cord-354833-vvlsqy36 79 31 a a DT cord-354833-vvlsqy36 79 32 computer computer NN cord-354833-vvlsqy36 79 33 , , , cord-354833-vvlsqy36 79 34 placed place VBN cord-354833-vvlsqy36 79 35 in in IN cord-354833-vvlsqy36 79 36 a a DT cord-354833-vvlsqy36 79 37 correct correct JJ cord-354833-vvlsqy36 79 38 ontological ontological JJ cord-354833-vvlsqy36 79 39 format format NN cord-354833-vvlsqy36 79 40 , , , cord-354833-vvlsqy36 79 41 and and CC cord-354833-vvlsqy36 79 42 used use VBN cord-354833-vvlsqy36 79 43 by by IN cord-354833-vvlsqy36 79 44 a a DT cord-354833-vvlsqy36 79 45 database database NN cord-354833-vvlsqy36 79 46 ) ) -RRB- cord-354833-vvlsqy36 79 47 . . . cord-354833-vvlsqy36 80 1 In in IN cord-354833-vvlsqy36 80 2 its -PRON- PRP$ cord-354833-vvlsqy36 80 3 basic basic JJ cord-354833-vvlsqy36 80 4 , , , cord-354833-vvlsqy36 80 5 but but CC cord-354833-vvlsqy36 80 6 already already RB cord-354833-vvlsqy36 80 7 highly highly RB cord-354833-vvlsqy36 80 8 useful useful JJ cord-354833-vvlsqy36 80 9 , , , cord-354833-vvlsqy36 80 10 form form NN cord-354833-vvlsqy36 80 11 , , , cord-354833-vvlsqy36 80 12 a a DT cord-354833-vvlsqy36 80 13 text text NN cord-354833-vvlsqy36 80 14 is be VBZ cord-354833-vvlsqy36 80 15 classified classify VBN cord-354833-vvlsqy36 80 16 into into IN cord-354833-vvlsqy36 80 17 one one CD cord-354833-vvlsqy36 80 18 of of IN cord-354833-vvlsqy36 80 19 several several JJ cord-354833-vvlsqy36 80 20 categories category NNS cord-354833-vvlsqy36 80 21 . . . cord-354833-vvlsqy36 81 1 For for IN cord-354833-vvlsqy36 81 2 the the DT cord-354833-vvlsqy36 81 3 IEDB IEDB NNP cord-354833-vvlsqy36 81 4 , , , cord-354833-vvlsqy36 81 5 we -PRON- PRP cord-354833-vvlsqy36 81 6 are be VBP cord-354833-vvlsqy36 81 7 using use VBG cord-354833-vvlsqy36 81 8 such such JJ cord-354833-vvlsqy36 81 9 categorizations categorization NNS cord-354833-vvlsqy36 81 10 to to TO cord-354833-vvlsqy36 81 11 identify identify VB cord-354833-vvlsqy36 81 12 abstracts abstract NNS cord-354833-vvlsqy36 81 13 listed list VBN cord-354833-vvlsqy36 81 14 in in IN cord-354833-vvlsqy36 81 15 the the DT cord-354833-vvlsqy36 81 16 PubMed PubMed NNP cord-354833-vvlsqy36 81 17 database database NN cord-354833-vvlsqy36 81 18 that that WDT cord-354833-vvlsqy36 81 19 probably probably RB cord-354833-vvlsqy36 81 20 contain contain VBP cord-354833-vvlsqy36 81 21 epitoperelated epitoperelated JJ cord-354833-vvlsqy36 81 22 information information NN cord-354833-vvlsqy36 81 23 -a -a , cord-354833-vvlsqy36 81 24 similar similar JJ cord-354833-vvlsqy36 81 25 approach approach NN cord-354833-vvlsqy36 81 26 to to IN cord-354833-vvlsqy36 81 27 that that DT cord-354833-vvlsqy36 81 28 which which WDT cord-354833-vvlsqy36 81 29 has have VBZ cord-354833-vvlsqy36 81 30 been be VBN cord-354833-vvlsqy36 81 31 successfully successfully RB cord-354833-vvlsqy36 81 32 applied apply VBN cord-354833-vvlsqy36 81 33 by by IN cord-354833-vvlsqy36 81 34 others other NNS cord-354833-vvlsqy36 81 35 23 23 CD cord-354833-vvlsqy36 81 36 , , , cord-354833-vvlsqy36 81 37 24 24 CD cord-354833-vvlsqy36 81 38 . . . cord-354833-vvlsqy36 82 1 Ideally ideally RB cord-354833-vvlsqy36 82 2 , , , cord-354833-vvlsqy36 82 3 one one PRP cord-354833-vvlsqy36 82 4 would would MD cord-354833-vvlsqy36 82 5 like like VB cord-354833-vvlsqy36 82 6 to to TO cord-354833-vvlsqy36 82 7 go go VB cord-354833-vvlsqy36 82 8 further further RB cord-354833-vvlsqy36 82 9 and and CC cord-354833-vvlsqy36 82 10 train train VB cord-354833-vvlsqy36 82 11 a a DT cord-354833-vvlsqy36 82 12 knowledge knowledge NN cord-354833-vvlsqy36 82 13 extraction extraction NN cord-354833-vvlsqy36 82 14 algorithm algorithm NN cord-354833-vvlsqy36 82 15 to to TO cord-354833-vvlsqy36 82 16 recognize recognize VB cord-354833-vvlsqy36 82 17 complex complex JJ cord-354833-vvlsqy36 82 18 immunological immunological JJ cord-354833-vvlsqy36 82 19 information information NN cord-354833-vvlsqy36 82 20 from from IN cord-354833-vvlsqy36 82 21 text text NN cord-354833-vvlsqy36 82 22 , , , cord-354833-vvlsqy36 82 23 such such JJ cord-354833-vvlsqy36 82 24 as as IN cord-354833-vvlsqy36 82 25 ' ' `` cord-354833-vvlsqy36 82 26 T t NN cord-354833-vvlsqy36 82 27 - - HYPH cord-354833-vvlsqy36 82 28 cell cell NN cord-354833-vvlsqy36 82 29 epitopes epitope NNS cord-354833-vvlsqy36 82 30 were be VBD cord-354833-vvlsqy36 82 31 recognized recognize VBN cord-354833-vvlsqy36 82 32 in in IN cord-354833-vvlsqy36 82 33 macaques macaque NNS cord-354833-vvlsqy36 82 34 , , , cord-354833-vvlsqy36 82 35 derived derive VBN cord-354833-vvlsqy36 82 36 from from IN cord-354833-vvlsqy36 82 37 SARS SARS NNP cord-354833-vvlsqy36 82 38 and and CC cord-354833-vvlsqy36 82 39 associated associate VBN cord-354833-vvlsqy36 82 40 with with IN cord-354833-vvlsqy36 82 41 interferon interferon NN cord-354833-vvlsqy36 82 42 release release NN cord-354833-vvlsqy36 82 43 ' ' '' cord-354833-vvlsqy36 82 44 . . . cord-354833-vvlsqy36 83 1 The the DT cord-354833-vvlsqy36 83 2 challenge challenge NN cord-354833-vvlsqy36 83 3 has have VBZ cord-354833-vvlsqy36 83 4 , , , cord-354833-vvlsqy36 83 5 however however RB cord-354833-vvlsqy36 83 6 , , , cord-354833-vvlsqy36 83 7 been be VBN cord-354833-vvlsqy36 83 8 that that WDT cord-354833-vvlsqy36 83 9 currently currently RB cord-354833-vvlsqy36 83 10 available available JJ cord-354833-vvlsqy36 83 11 text text NN cord-354833-vvlsqy36 83 12 - - HYPH cord-354833-vvlsqy36 83 13 recognition recognition NN cord-354833-vvlsqy36 83 14 programs program NNS cord-354833-vvlsqy36 83 15 tend tend VBP cord-354833-vvlsqy36 83 16 to to TO cord-354833-vvlsqy36 83 17 lose lose VB cord-354833-vvlsqy36 83 18 efficacy efficacy NN cord-354833-vvlsqy36 83 19 when when WRB cord-354833-vvlsqy36 83 20 interpreting interpret VBG cord-354833-vvlsqy36 83 21 complex complex JJ cord-354833-vvlsqy36 83 22 sentences sentence NNS cord-354833-vvlsqy36 83 23 , , , cord-354833-vvlsqy36 83 24 not not RB cord-354833-vvlsqy36 83 25 to to TO cord-354833-vvlsqy36 83 26 mention mention VB cord-354833-vvlsqy36 83 27 when when WRB cord-354833-vvlsqy36 83 28 gathering gather VBG cord-354833-vvlsqy36 83 29 information information NN cord-354833-vvlsqy36 83 30 distributed distribute VBN cord-354833-vvlsqy36 83 31 throughout throughout IN cord-354833-vvlsqy36 83 32 an an DT cord-354833-vvlsqy36 83 33 article article NN cord-354833-vvlsqy36 83 34 ( ( -LRB- cord-354833-vvlsqy36 83 35 for for IN cord-354833-vvlsqy36 83 36 example example NN cord-354833-vvlsqy36 83 37 , , , cord-354833-vvlsqy36 83 38 the the DT cord-354833-vvlsqy36 83 39 fact fact NN cord-354833-vvlsqy36 83 40 that that IN cord-354833-vvlsqy36 83 41 the the DT cord-354833-vvlsqy36 83 42 immune immune JJ cord-354833-vvlsqy36 83 43 response response NN cord-354833-vvlsqy36 83 44 was be VBD cord-354833-vvlsqy36 83 45 observed observe VBN cord-354833-vvlsqy36 83 46 in in IN cord-354833-vvlsqy36 83 47 macaques macaque NNS cord-354833-vvlsqy36 83 48 may may MD cord-354833-vvlsqy36 83 49 be be VB cord-354833-vvlsqy36 83 50 found find VBN cord-354833-vvlsqy36 83 51 in in IN cord-354833-vvlsqy36 83 52 the the DT cord-354833-vvlsqy36 83 53 materials material NNS cord-354833-vvlsqy36 83 54 and and CC cord-354833-vvlsqy36 83 55 methods method NNS cord-354833-vvlsqy36 83 56 , , , cord-354833-vvlsqy36 83 57 whereas whereas IN cord-354833-vvlsqy36 83 58 the the DT cord-354833-vvlsqy36 83 59 actual actual JJ cord-354833-vvlsqy36 83 60 data datum NNS cord-354833-vvlsqy36 83 61 may may MD cord-354833-vvlsqy36 83 62 be be VB cord-354833-vvlsqy36 83 63 found find VBN cord-354833-vvlsqy36 83 64 in in IN cord-354833-vvlsqy36 83 65 a a DT cord-354833-vvlsqy36 83 66 figure figure NN cord-354833-vvlsqy36 83 67 several several JJ cord-354833-vvlsqy36 83 68 pages page NNS cord-354833-vvlsqy36 83 69 away away RB cord-354833-vvlsqy36 83 70 from from IN cord-354833-vvlsqy36 83 71 the the DT cord-354833-vvlsqy36 83 72 methods method NNS cord-354833-vvlsqy36 83 73 section section NN cord-354833-vvlsqy36 83 74 ) ) -RRB- cord-354833-vvlsqy36 83 75 . . . cord-354833-vvlsqy36 84 1 The the DT cord-354833-vvlsqy36 84 2 lack lack NN cord-354833-vvlsqy36 84 3 of of IN cord-354833-vvlsqy36 84 4 available available JJ cord-354833-vvlsqy36 84 5 training training NN cord-354833-vvlsqy36 84 6 sets set NNS cord-354833-vvlsqy36 84 7 has have VBZ cord-354833-vvlsqy36 84 8 been be VBN cord-354833-vvlsqy36 84 9 a a DT cord-354833-vvlsqy36 84 10 significant significant JJ cord-354833-vvlsqy36 84 11 stumbling stumbling NN cord-354833-vvlsqy36 84 12 block block NN cord-354833-vvlsqy36 84 13 in in IN cord-354833-vvlsqy36 84 14 progressive progressive JJ cord-354833-vvlsqy36 84 15 training training NN cord-354833-vvlsqy36 84 16 towards towards IN cord-354833-vvlsqy36 84 17 accomplishing accomplish VBG cord-354833-vvlsqy36 84 18 more more RBR cord-354833-vvlsqy36 84 19 complex complex JJ cord-354833-vvlsqy36 84 20 tasks task NNS cord-354833-vvlsqy36 84 21 . . . cord-354833-vvlsqy36 85 1 However however RB cord-354833-vvlsqy36 85 2 , , , cord-354833-vvlsqy36 85 3 the the DT cord-354833-vvlsqy36 85 4 IEDB IEDB NNP cord-354833-vvlsqy36 85 5 curation curation NN cord-354833-vvlsqy36 85 6 may may MD cord-354833-vvlsqy36 85 7 offer offer VB cord-354833-vvlsqy36 85 8 an an DT cord-354833-vvlsqy36 85 9 opportunity opportunity NN cord-354833-vvlsqy36 85 10 to to TO cord-354833-vvlsqy36 85 11 make make VB cord-354833-vvlsqy36 85 12 advances advance NNS cord-354833-vvlsqy36 85 13 in in IN cord-354833-vvlsqy36 85 14 the the DT cord-354833-vvlsqy36 85 15 field field NN cord-354833-vvlsqy36 85 16 , , , cord-354833-vvlsqy36 85 17 because because IN cord-354833-vvlsqy36 85 18 thousands thousand NNS cord-354833-vvlsqy36 85 19 of of IN cord-354833-vvlsqy36 85 20 different different JJ cord-354833-vvlsqy36 85 21 manuscripts manuscript NNS cord-354833-vvlsqy36 85 22 are be VBP cord-354833-vvlsqy36 85 23 being be VBG cord-354833-vvlsqy36 85 24 curated curate VBN cord-354833-vvlsqy36 85 25 . . . cord-354833-vvlsqy36 86 1 This this DT cord-354833-vvlsqy36 86 2 provides provide VBZ cord-354833-vvlsqy36 86 3 a a DT cord-354833-vvlsqy36 86 4 comprehensive comprehensive JJ cord-354833-vvlsqy36 86 5 set set NN cord-354833-vvlsqy36 86 6 of of IN cord-354833-vvlsqy36 86 7 immunological immunological JJ cord-354833-vvlsqy36 86 8 papers paper NNS cord-354833-vvlsqy36 86 9 and and CC cord-354833-vvlsqy36 86 10 matching match VBG cord-354833-vvlsqy36 86 11 records record NNS cord-354833-vvlsqy36 86 12 of of IN cord-354833-vvlsqy36 86 13 curated curate VBN cord-354833-vvlsqy36 86 14 information information NN cord-354833-vvlsqy36 86 15 , , , cord-354833-vvlsqy36 86 16 which which WDT cord-354833-vvlsqy36 86 17 includes include VBZ cord-354833-vvlsqy36 86 18 categories category NNS cord-354833-vvlsqy36 86 19 such such JJ cord-354833-vvlsqy36 86 20 as as IN cord-354833-vvlsqy36 86 21 where where WRB cord-354833-vvlsqy36 86 22 in in IN cord-354833-vvlsqy36 86 23 the the DT cord-354833-vvlsqy36 86 24 manuscript manuscript NN cord-354833-vvlsqy36 86 25 the the DT cord-354833-vvlsqy36 86 26 information information NN cord-354833-vvlsqy36 86 27 was be VBD cord-354833-vvlsqy36 86 28 gathered gather VBN cord-354833-vvlsqy36 86 29 from from IN cord-354833-vvlsqy36 86 30 . . . cord-354833-vvlsqy36 87 1 Such such JJ cord-354833-vvlsqy36 87 2 datasets dataset NNS cord-354833-vvlsqy36 87 3 have have VBP cord-354833-vvlsqy36 87 4 proven prove VBN cord-354833-vvlsqy36 87 5 to to TO cord-354833-vvlsqy36 87 6 be be VB cord-354833-vvlsqy36 87 7 invaluable invaluable JJ cord-354833-vvlsqy36 87 8 in in IN cord-354833-vvlsqy36 87 9 deriving derive VBG cord-354833-vvlsqy36 87 10 ever ever RB cord-354833-vvlsqy36 87 11 - - HYPH cord-354833-vvlsqy36 87 12 more more RBR cord-354833-vvlsqy36 87 13 potent potent JJ cord-354833-vvlsqy36 87 14 text text NN cord-354833-vvlsqy36 87 15 - - HYPH cord-354833-vvlsqy36 87 16 mining mining NN cord-354833-vvlsqy36 87 17 tools tool NNS cord-354833-vvlsqy36 87 18 25 25 CD cord-354833-vvlsqy36 87 19 . . . cord-354833-vvlsqy36 88 1 There there EX cord-354833-vvlsqy36 88 2 are be VBP cord-354833-vvlsqy36 88 3 numerous numerous JJ cord-354833-vvlsqy36 88 4 ways way NNS cord-354833-vvlsqy36 88 5 of of IN cord-354833-vvlsqy36 88 6 accessing access VBG cord-354833-vvlsqy36 88 7 the the DT cord-354833-vvlsqy36 88 8 data datum NNS cord-354833-vvlsqy36 88 9 in in IN cord-354833-vvlsqy36 88 10 the the DT cord-354833-vvlsqy36 88 11 IEDB IEDB NNP cord-354833-vvlsqy36 88 12 that that WDT cord-354833-vvlsqy36 88 13 are be VBP cord-354833-vvlsqy36 88 14 tailored tailor VBN cord-354833-vvlsqy36 88 15 to to IN cord-354833-vvlsqy36 88 16 different different JJ cord-354833-vvlsqy36 88 17 user user NN cord-354833-vvlsqy36 88 18 groups group NNS cord-354833-vvlsqy36 88 19 . . . cord-354833-vvlsqy36 89 1 Searches search NNS cord-354833-vvlsqy36 89 2 come come VBP cord-354833-vvlsqy36 89 3 in in IN cord-354833-vvlsqy36 89 4 three three CD cord-354833-vvlsqy36 89 5 types type NNS cord-354833-vvlsqy36 89 6 : : : cord-354833-vvlsqy36 89 7 quick quick JJ cord-354833-vvlsqy36 89 8 , , , cord-354833-vvlsqy36 89 9 simple simple JJ cord-354833-vvlsqy36 89 10 and and CC cord-354833-vvlsqy36 89 11 advanced advanced JJ cord-354833-vvlsqy36 89 12 . . . cord-354833-vvlsqy36 90 1 The the DT cord-354833-vvlsqy36 90 2 quick quick JJ cord-354833-vvlsqy36 90 3 search search NN cord-354833-vvlsqy36 90 4 scans scan VBZ cord-354833-vvlsqy36 90 5 the the DT cord-354833-vvlsqy36 90 6 entire entire JJ cord-354833-vvlsqy36 90 7 text text NN cord-354833-vvlsqy36 90 8 of of IN cord-354833-vvlsqy36 90 9 a a DT cord-354833-vvlsqy36 90 10 curated curate VBN cord-354833-vvlsqy36 90 11 record record NN cord-354833-vvlsqy36 90 12 for for IN cord-354833-vvlsqy36 90 13 any any DT cord-354833-vvlsqy36 90 14 occurrence occurrence NN cord-354833-vvlsqy36 90 15 of of IN cord-354833-vvlsqy36 90 16 the the DT cord-354833-vvlsqy36 90 17 specified specify VBN cord-354833-vvlsqy36 90 18 search search NN cord-354833-vvlsqy36 90 19 term term NN cord-354833-vvlsqy36 90 20 . . . cord-354833-vvlsqy36 91 1 The the DT cord-354833-vvlsqy36 91 2 simple simple JJ cord-354833-vvlsqy36 91 3 search search NN cord-354833-vvlsqy36 91 4 allows allow VBZ cord-354833-vvlsqy36 91 5 for for IN cord-354833-vvlsqy36 91 6 more more RBR cord-354833-vvlsqy36 91 7 targeted targeted JJ cord-354833-vvlsqy36 91 8 queries query NNS cord-354833-vvlsqy36 91 9 without without IN cord-354833-vvlsqy36 91 10 overwhelming overwhelm VBG cord-354833-vvlsqy36 91 11 the the DT cord-354833-vvlsqy36 91 12 user user NN cord-354833-vvlsqy36 91 13 with with IN cord-354833-vvlsqy36 91 14 choices choice NNS cord-354833-vvlsqy36 91 15 . . . cord-354833-vvlsqy36 92 1 It -PRON- PRP cord-354833-vvlsqy36 92 2 allows allow VBZ cord-354833-vvlsqy36 92 3 for for IN cord-354833-vvlsqy36 92 4 the the DT cord-354833-vvlsqy36 92 5 most most RBS cord-354833-vvlsqy36 92 6 - - HYPH cord-354833-vvlsqy36 92 7 commonly commonly RB cord-354833-vvlsqy36 92 8 desired desire VBN cord-354833-vvlsqy36 92 9 types type NNS cord-354833-vvlsqy36 92 10 of of IN cord-354833-vvlsqy36 92 11 query query NN cord-354833-vvlsqy36 92 12 , , , cord-354833-vvlsqy36 92 13 such such JJ cord-354833-vvlsqy36 92 14 as as IN cord-354833-vvlsqy36 92 15 epitopes epitope NNS cord-354833-vvlsqy36 92 16 that that WDT cord-354833-vvlsqy36 92 17 are be VBP cord-354833-vvlsqy36 92 18 recognized recognize VBN cord-354833-vvlsqy36 92 19 by by IN cord-354833-vvlsqy36 92 20 T T NNP cord-354833-vvlsqy36 92 21 cells cell NNS cord-354833-vvlsqy36 92 22 restricted restrict VBN cord-354833-vvlsqy36 92 23 by by IN cord-354833-vvlsqy36 92 24 HLA HLA NNP cord-354833-vvlsqy36 92 25 - - HYPH cord-354833-vvlsqy36 92 26 A*0201 A*0201 NNP cord-354833-vvlsqy36 92 27 . . . cord-354833-vvlsqy36 93 1 In in IN cord-354833-vvlsqy36 93 2 the the DT cord-354833-vvlsqy36 93 3 advanced advanced JJ cord-354833-vvlsqy36 93 4 query query NN cord-354833-vvlsqy36 93 5 , , , cord-354833-vvlsqy36 93 6 values value NNS cord-354833-vvlsqy36 93 7 for for IN cord-354833-vvlsqy36 93 8 all all DT cord-354833-vvlsqy36 93 9 of of IN cord-354833-vvlsqy36 93 10 the the DT cord-354833-vvlsqy36 93 11 more more JJR cord-354833-vvlsqy36 93 12 than than IN cord-354833-vvlsqy36 93 13 300 300 CD cord-354833-vvlsqy36 93 14 database database NN cord-354833-vvlsqy36 93 15 fields field NNS cord-354833-vvlsqy36 93 16 can can MD cord-354833-vvlsqy36 93 17 be be VB cord-354833-vvlsqy36 93 18 specified specify VBN cord-354833-vvlsqy36 93 19 , , , cord-354833-vvlsqy36 93 20 and and CC cord-354833-vvlsqy36 93 21 it -PRON- PRP cord-354833-vvlsqy36 93 22 is be VBZ cord-354833-vvlsqy36 93 23 also also RB cord-354833-vvlsqy36 93 24 possible possible JJ cord-354833-vvlsqy36 93 25 to to TO cord-354833-vvlsqy36 93 26 customize customize VB cord-354833-vvlsqy36 93 27 the the DT cord-354833-vvlsqy36 93 28 reporting reporting NN cord-354833-vvlsqy36 93 29 format format NN cord-354833-vvlsqy36 93 30 ( ( -LRB- cord-354833-vvlsqy36 93 31 FIG fig NN cord-354833-vvlsqy36 93 32 . . . cord-354833-vvlsqy36 93 33 2 2 CD cord-354833-vvlsqy36 93 34 ) ) -RRB- cord-354833-vvlsqy36 93 35 . . . cord-354833-vvlsqy36 94 1 In in IN cord-354833-vvlsqy36 94 2 addition addition NN cord-354833-vvlsqy36 94 3 to to IN cord-354833-vvlsqy36 94 4 the the DT cord-354833-vvlsqy36 94 5 search search NN cord-354833-vvlsqy36 94 6 interfaces interface NNS cord-354833-vvlsqy36 94 7 , , , cord-354833-vvlsqy36 94 8 it -PRON- PRP cord-354833-vvlsqy36 94 9 is be VBZ cord-354833-vvlsqy36 94 10 also also RB cord-354833-vvlsqy36 94 11 possible possible JJ cord-354833-vvlsqy36 94 12 to to TO cord-354833-vvlsqy36 94 13 browse browse VB cord-354833-vvlsqy36 94 14 for for IN cord-354833-vvlsqy36 94 15 epitopes epitope NNS cord-354833-vvlsqy36 94 16 through through IN cord-354833-vvlsqy36 94 17 the the DT cord-354833-vvlsqy36 94 18 IEDB IEDB NNP cord-354833-vvlsqy36 94 19 records record NNS cord-354833-vvlsqy36 94 20 by by IN cord-354833-vvlsqy36 94 21 their -PRON- PRP$ cord-354833-vvlsqy36 94 22 MHC MHC NNP cord-354833-vvlsqy36 94 23 restriction restriction NN cord-354833-vvlsqy36 94 24 or or CC cord-354833-vvlsqy36 94 25 source source NN cord-354833-vvlsqy36 94 26 species specie NNS cord-354833-vvlsqy36 94 27 . . . cord-354833-vvlsqy36 95 1 Finally finally RB cord-354833-vvlsqy36 95 2 , , , cord-354833-vvlsqy36 95 3 the the DT cord-354833-vvlsqy36 95 4 entire entire JJ cord-354833-vvlsqy36 95 5 content content NN cord-354833-vvlsqy36 95 6 of of IN cord-354833-vvlsqy36 95 7 the the DT cord-354833-vvlsqy36 95 8 IEDB IEDB NNP cord-354833-vvlsqy36 95 9 is be VBZ cord-354833-vvlsqy36 95 10 fully fully RB cord-354833-vvlsqy36 95 11 downloadable downloadable JJ cord-354833-vvlsqy36 95 12 as as IN cord-354833-vvlsqy36 95 13 a a DT cord-354833-vvlsqy36 95 14 single single JJ cord-354833-vvlsqy36 95 15 file file NN cord-354833-vvlsqy36 95 16 in in IN cord-354833-vvlsqy36 95 17 XML xml NN cord-354833-vvlsqy36 95 18 format format NN cord-354833-vvlsqy36 95 19 . . . cord-354833-vvlsqy36 96 1 Numerous numerous JJ cord-354833-vvlsqy36 96 2 tools tool NNS cord-354833-vvlsqy36 96 3 have have VBP cord-354833-vvlsqy36 96 4 been be VBN cord-354833-vvlsqy36 96 5 developed develop VBN cord-354833-vvlsqy36 96 6 to to TO cord-354833-vvlsqy36 96 7 predict predict VB cord-354833-vvlsqy36 96 8 the the DT cord-354833-vvlsqy36 96 9 presence presence NN cord-354833-vvlsqy36 96 10 of of IN cord-354833-vvlsqy36 96 11 epitopes epitope NNS cord-354833-vvlsqy36 96 12 in in IN cord-354833-vvlsqy36 96 13 protein protein NN cord-354833-vvlsqy36 96 14 sequences sequence NNS cord-354833-vvlsqy36 96 15 ( ( -LRB- cord-354833-vvlsqy36 96 16 see see VB cord-354833-vvlsqy36 96 17 for for IN cord-354833-vvlsqy36 96 18 example example NN cord-354833-vvlsqy36 96 19 the the DT cord-354833-vvlsqy36 96 20 listings listing NNS cord-354833-vvlsqy36 96 21 in in IN cord-354833-vvlsqy36 96 22 REF REF NNP cord-354833-vvlsqy36 96 23 . . . cord-354833-vvlsqy36 96 24 11 11 CD cord-354833-vvlsqy36 96 25 ) ) -RRB- cord-354833-vvlsqy36 96 26 , , , cord-354833-vvlsqy36 96 27 and and CC cord-354833-vvlsqy36 96 28 several several JJ cord-354833-vvlsqy36 96 29 groups group NNS cord-354833-vvlsqy36 96 30 have have VBP cord-354833-vvlsqy36 96 31 used use VBN cord-354833-vvlsqy36 96 32 them -PRON- PRP cord-354833-vvlsqy36 96 33 successfully successfully RB cord-354833-vvlsqy36 96 34 to to TO cord-354833-vvlsqy36 96 35 map map VB cord-354833-vvlsqy36 96 36 new new JJ cord-354833-vvlsqy36 96 37 epitopes epitope NNS cord-354833-vvlsqy36 96 38 and and CC cord-354833-vvlsqy36 96 39 for for IN cord-354833-vvlsqy36 96 40 other other JJ cord-354833-vvlsqy36 96 41 applications application NNS cord-354833-vvlsqy36 96 42 ( ( -LRB- cord-354833-vvlsqy36 96 43 reviewed review VBN cord-354833-vvlsqy36 96 44 in in IN cord-354833-vvlsqy36 96 45 REF REF NNP cord-354833-vvlsqy36 96 46 . . . cord-354833-vvlsqy36 96 47 26 26 CD cord-354833-vvlsqy36 96 48 ) ) -RRB- cord-354833-vvlsqy36 96 49 . . . cord-354833-vvlsqy36 97 1 The the DT cord-354833-vvlsqy36 97 2 IEDB IEDB NNP cord-354833-vvlsqy36 97 3 provides provide VBZ cord-354833-vvlsqy36 97 4 several several JJ cord-354833-vvlsqy36 97 5 tools tool NNS cord-354833-vvlsqy36 97 6 to to TO cord-354833-vvlsqy36 97 7 predict predict VB cord-354833-vvlsqy36 97 8 peptide peptide NN cord-354833-vvlsqy36 97 9 binding binding NN cord-354833-vvlsqy36 97 10 to to IN cord-354833-vvlsqy36 97 11 MHC MHC NNP cord-354833-vvlsqy36 97 12 class class NN cord-354833-vvlsqy36 98 1 I -PRON- PRP cord-354833-vvlsqy36 98 2 molecules molecule NNS cord-354833-vvlsqy36 98 3 , , , cord-354833-vvlsqy36 98 4 and and CC cord-354833-vvlsqy36 98 5 these these DT cord-354833-vvlsqy36 98 6 were be VBD cord-354833-vvlsqy36 98 7 recently recently RB cord-354833-vvlsqy36 98 8 compared compare VBN cord-354833-vvlsqy36 98 9 to to IN cord-354833-vvlsqy36 98 10 the the DT cord-354833-vvlsqy36 98 11 large large JJ cord-354833-vvlsqy36 98 12 set set NN cord-354833-vvlsqy36 98 13 of of IN cord-354833-vvlsqy36 98 14 tools tool NNS cord-354833-vvlsqy36 98 15 that that WDT cord-354833-vvlsqy36 98 16 are be VBP cord-354833-vvlsqy36 98 17 available available JJ cord-354833-vvlsqy36 98 18 elsewhere elsewhere RB cord-354833-vvlsqy36 98 19 on on IN cord-354833-vvlsqy36 98 20 the the DT cord-354833-vvlsqy36 98 21 internet internet NN cord-354833-vvlsqy36 98 22 27 27 CD cord-354833-vvlsqy36 98 23 . . . cord-354833-vvlsqy36 99 1 Such such PDT cord-354833-vvlsqy36 99 2 a a DT cord-354833-vvlsqy36 99 3 large large JJ cord-354833-vvlsqy36 99 4 - - HYPH cord-354833-vvlsqy36 99 5 scale scale NN cord-354833-vvlsqy36 99 6 comparison comparison NN cord-354833-vvlsqy36 99 7 is be VBZ cord-354833-vvlsqy36 99 8 meant mean VBN cord-354833-vvlsqy36 99 9 to to TO cord-354833-vvlsqy36 99 10 inform inform VB cord-354833-vvlsqy36 99 11 tool tool NN cord-354833-vvlsqy36 99 12 users user NNS cord-354833-vvlsqy36 99 13 of of IN cord-354833-vvlsqy36 99 14 the the DT cord-354833-vvlsqy36 99 15 current current JJ cord-354833-vvlsqy36 99 16 state state NN cord-354833-vvlsqy36 99 17 of of IN cord-354833-vvlsqy36 99 18 the the DT cord-354833-vvlsqy36 99 19 art art NN cord-354833-vvlsqy36 99 20 . . . cord-354833-vvlsqy36 100 1 For for IN cord-354833-vvlsqy36 100 2 tool tool NN cord-354833-vvlsqy36 100 3 developers developer NNS cord-354833-vvlsqy36 100 4 , , , cord-354833-vvlsqy36 100 5 this this DT cord-354833-vvlsqy36 100 6 comparison comparison NN cord-354833-vvlsqy36 100 7 provides provide VBZ cord-354833-vvlsqy36 100 8 a a DT cord-354833-vvlsqy36 100 9 set set NN cord-354833-vvlsqy36 100 10 of of IN cord-354833-vvlsqy36 100 11 benchmark benchmark JJ cord-354833-vvlsqy36 100 12 data datum NNS cord-354833-vvlsqy36 100 13 with with IN cord-354833-vvlsqy36 100 14 which which WDT cord-354833-vvlsqy36 100 15 to to TO cord-354833-vvlsqy36 100 16 evaluate evaluate VB cord-354833-vvlsqy36 100 17 newly newly RB cord-354833-vvlsqy36 100 18 developed develop VBN cord-354833-vvlsqy36 100 19 tools tool NNS cord-354833-vvlsqy36 100 20 against against IN cord-354833-vvlsqy36 100 21 , , , cord-354833-vvlsqy36 100 22 and and CC cord-354833-vvlsqy36 100 23 it -PRON- PRP cord-354833-vvlsqy36 100 24 instructs instruct VBZ cord-354833-vvlsqy36 100 25 them -PRON- PRP cord-354833-vvlsqy36 100 26 on on IN cord-354833-vvlsqy36 100 27 which which WDT cord-354833-vvlsqy36 100 28 approaches approach NNS cord-354833-vvlsqy36 100 29 have have VBP cord-354833-vvlsqy36 100 30 proven prove VBN cord-354833-vvlsqy36 100 31 to to TO cord-354833-vvlsqy36 100 32 be be VB cord-354833-vvlsqy36 100 33 successful successful JJ cord-354833-vvlsqy36 100 34 . . . cord-354833-vvlsqy36 101 1 In in IN cord-354833-vvlsqy36 101 2 combination combination NN cord-354833-vvlsqy36 101 3 with with IN cord-354833-vvlsqy36 101 4 predicting predict VBG cord-354833-vvlsqy36 101 5 the the DT cord-354833-vvlsqy36 101 6 ability ability NN cord-354833-vvlsqy36 101 7 of of IN cord-354833-vvlsqy36 101 8 a a DT cord-354833-vvlsqy36 101 9 particular particular JJ cord-354833-vvlsqy36 101 10 peptide peptide JJ cord-354833-vvlsqy36 101 11 sequence sequence NN cord-354833-vvlsqy36 101 12 to to TO cord-354833-vvlsqy36 101 13 bind bind VB cord-354833-vvlsqy36 101 14 MHC MHC NNP cord-354833-vvlsqy36 101 15 class class NN cord-354833-vvlsqy36 102 1 I -PRON- PRP cord-354833-vvlsqy36 102 2 molecules molecule NNS cord-354833-vvlsqy36 102 3 , , , cord-354833-vvlsqy36 102 4 predictions prediction NNS cord-354833-vvlsqy36 102 5 of of IN cord-354833-vvlsqy36 102 6 its -PRON- PRP$ cord-354833-vvlsqy36 102 7 processing processing NN cord-354833-vvlsqy36 102 8 by by IN cord-354833-vvlsqy36 102 9 the the DT cord-354833-vvlsqy36 102 10 proteasome proteasome NN cord-354833-vvlsqy36 102 11 and and CC cord-354833-vvlsqy36 102 12 transport transport NN cord-354833-vvlsqy36 102 13 by by IN cord-354833-vvlsqy36 102 14 the the DT cord-354833-vvlsqy36 102 15 transporter transporter NN cord-354833-vvlsqy36 102 16 associated associate VBN cord-354833-vvlsqy36 102 17 with with IN cord-354833-vvlsqy36 102 18 antigen antigen NN cord-354833-vvlsqy36 102 19 processing processing NN cord-354833-vvlsqy36 102 20 are be VBP cord-354833-vvlsqy36 102 21 also also RB cord-354833-vvlsqy36 102 22 made make VBN cord-354833-vvlsqy36 102 23 available available JJ cord-354833-vvlsqy36 102 24 . . . cord-354833-vvlsqy36 103 1 These these DT cord-354833-vvlsqy36 103 2 can can MD cord-354833-vvlsqy36 103 3 be be VB cord-354833-vvlsqy36 103 4 used use VBN cord-354833-vvlsqy36 103 5 to to TO cord-354833-vvlsqy36 103 6 further further RB cord-354833-vvlsqy36 103 7 narrow narrow VB cord-354833-vvlsqy36 103 8 the the DT cord-354833-vvlsqy36 103 9 set set NN cord-354833-vvlsqy36 103 10 of of IN cord-354833-vvlsqy36 103 11 candidate candidate NN cord-354833-vvlsqy36 103 12 T t NN cord-354833-vvlsqy36 103 13 - - HYPH cord-354833-vvlsqy36 103 14 cell cell NN cord-354833-vvlsqy36 103 15 epitopes epitope NNS cord-354833-vvlsqy36 103 16 from from IN cord-354833-vvlsqy36 103 17 a a DT cord-354833-vvlsqy36 103 18 protein protein NN cord-354833-vvlsqy36 103 19 sequence sequence NN cord-354833-vvlsqy36 103 20 . . . cord-354833-vvlsqy36 104 1 There there EX cord-354833-vvlsqy36 104 2 is be VBZ cord-354833-vvlsqy36 104 3 an an DT cord-354833-vvlsqy36 104 4 ongoing ongoing JJ cord-354833-vvlsqy36 104 5 formal formal JJ cord-354833-vvlsqy36 104 6 evaluation evaluation NN cord-354833-vvlsqy36 104 7 of of IN cord-354833-vvlsqy36 104 8 these these DT cord-354833-vvlsqy36 104 9 tools tool NNS cord-354833-vvlsqy36 104 10 that that WDT cord-354833-vvlsqy36 104 11 takes take VBZ cord-354833-vvlsqy36 104 12 advantage advantage NN cord-354833-vvlsqy36 104 13 of of IN cord-354833-vvlsqy36 104 14 the the DT cord-354833-vvlsqy36 104 15 data datum NNS cord-354833-vvlsqy36 104 16 collected collect VBN cord-354833-vvlsqy36 104 17 in in IN cord-354833-vvlsqy36 104 18 the the DT cord-354833-vvlsqy36 104 19 IEDB IEDB NNP cord-354833-vvlsqy36 104 20 , , , cord-354833-vvlsqy36 104 21 as as RB cord-354833-vvlsqy36 104 22 well well RB cord-354833-vvlsqy36 104 23 as as IN cord-354833-vvlsqy36 104 24 an an DT cord-354833-vvlsqy36 104 25 evaluation evaluation NN cord-354833-vvlsqy36 104 26 of of IN cord-354833-vvlsqy36 104 27 MHC MHC NNP cord-354833-vvlsqy36 104 28 - - HYPH cord-354833-vvlsqy36 104 29 class class NNP cord-354833-vvlsqy36 104 30 - - HYPH cord-354833-vvlsqy36 104 31 II ii NN cord-354833-vvlsqy36 104 32 - - HYPH cord-354833-vvlsqy36 104 33 binding bind VBG cord-354833-vvlsqy36 104 34 predictions prediction NNS cord-354833-vvlsqy36 104 35 . . . cord-354833-vvlsqy36 105 1 In in IN cord-354833-vvlsqy36 105 2 addition addition NN cord-354833-vvlsqy36 105 3 to to IN cord-354833-vvlsqy36 105 4 evaluations evaluation NNS cord-354833-vvlsqy36 105 5 of of IN cord-354833-vvlsqy36 105 6 existing exist VBG cord-354833-vvlsqy36 105 7 servers server NNS cord-354833-vvlsqy36 105 8 , , , cord-354833-vvlsqy36 105 9 we -PRON- PRP cord-354833-vvlsqy36 105 10 also also RB cord-354833-vvlsqy36 105 11 plan plan VBP cord-354833-vvlsqy36 105 12 to to TO cord-354833-vvlsqy36 105 13 hold hold VB cord-354833-vvlsqy36 105 14 prediction prediction NN cord-354833-vvlsqy36 105 15 contests contest NNS cord-354833-vvlsqy36 105 16 in in IN cord-354833-vvlsqy36 105 17 which which WDT cord-354833-vvlsqy36 105 18 interested interested JJ cord-354833-vvlsqy36 105 19 scientists scientist NNS cord-354833-vvlsqy36 105 20 can can MD cord-354833-vvlsqy36 105 21 submit submit VB cord-354833-vvlsqy36 105 22 their -PRON- PRP$ cord-354833-vvlsqy36 105 23 predictions prediction NNS cord-354833-vvlsqy36 105 24 for for IN cord-354833-vvlsqy36 105 25 a a DT cord-354833-vvlsqy36 105 26 set set NN cord-354833-vvlsqy36 105 27 of of IN cord-354833-vvlsqy36 105 28 targets target NNS cord-354833-vvlsqy36 105 29 . . . cord-354833-vvlsqy36 106 1 Such such JJ cord-354833-vvlsqy36 106 2 contests contest NNS cord-354833-vvlsqy36 106 3 have have VBP cord-354833-vvlsqy36 106 4 had have VBN cord-354833-vvlsqy36 106 5 a a DT cord-354833-vvlsqy36 106 6 tremendous tremendous JJ cord-354833-vvlsqy36 106 7 positive positive JJ cord-354833-vvlsqy36 106 8 impact impact NN cord-354833-vvlsqy36 106 9 in in IN cord-354833-vvlsqy36 106 10 the the DT cord-354833-vvlsqy36 106 11 evaluation evaluation NN cord-354833-vvlsqy36 106 12 and and CC cord-354833-vvlsqy36 106 13 prediction prediction NN cord-354833-vvlsqy36 106 14 of of IN cord-354833-vvlsqy36 106 15 protein protein NN cord-354833-vvlsqy36 106 16 structure structure NN cord-354833-vvlsqy36 106 17 28 28 CD cord-354833-vvlsqy36 106 18 . . . cord-354833-vvlsqy36 107 1 Figure figure NN cord-354833-vvlsqy36 107 2 1 1 CD cord-354833-vvlsqy36 107 3 | | NFP cord-354833-vvlsqy36 107 4 Generating generate VBG cord-354833-vvlsqy36 107 5 a a DT cord-354833-vvlsqy36 107 6 formal formal JJ cord-354833-vvlsqy36 107 7 ontology ontology NN cord-354833-vvlsqy36 107 8 for for IN cord-354833-vvlsqy36 107 9 the the DT cord-354833-vvlsqy36 107 10 Immune Immune NNP cord-354833-vvlsqy36 107 11 Epitope Epitope NNP cord-354833-vvlsqy36 107 12 Database database NN cord-354833-vvlsqy36 107 13 ( ( -LRB- cord-354833-vvlsqy36 107 14 IEDB IEDB NNP cord-354833-vvlsqy36 107 15 ) ) -RRB- cord-354833-vvlsqy36 107 16 . . . cord-354833-vvlsqy36 108 1 The the DT cord-354833-vvlsqy36 108 2 initial initial JJ cord-354833-vvlsqy36 108 3 ontology ontology NN cord-354833-vvlsqy36 108 4 of of IN cord-354833-vvlsqy36 108 5 the the DT cord-354833-vvlsqy36 108 6 IEDB IEDB NNP cord-354833-vvlsqy36 108 7 described describe VBD cord-354833-vvlsqy36 108 8 all all DT cord-354833-vvlsqy36 108 9 elements element NNS cord-354833-vvlsqy36 108 10 of of IN cord-354833-vvlsqy36 108 11 the the DT cord-354833-vvlsqy36 108 12 database database NN cord-354833-vvlsqy36 108 13 as as IN cord-354833-vvlsqy36 108 14 classes class NNS cord-354833-vvlsqy36 108 15 with with IN cord-354833-vvlsqy36 108 16 associated associate VBN cord-354833-vvlsqy36 108 17 characteristics characteristic NNS cord-354833-vvlsqy36 108 18 ( ( -LRB- cord-354833-vvlsqy36 108 19 left left JJ cord-354833-vvlsqy36 108 20 panel panel NN cord-354833-vvlsqy36 108 21 shows show VBZ cord-354833-vvlsqy36 108 22 this this DT cord-354833-vvlsqy36 108 23 for for IN cord-354833-vvlsqy36 108 24 the the DT cord-354833-vvlsqy36 108 25 immunogen immunogen NN cord-354833-vvlsqy36 108 26 class class NN cord-354833-vvlsqy36 108 27 ) ) -RRB- cord-354833-vvlsqy36 108 28 . . . cord-354833-vvlsqy36 109 1 In in IN cord-354833-vvlsqy36 109 2 the the DT cord-354833-vvlsqy36 109 3 development development NN cord-354833-vvlsqy36 109 4 process process NN cord-354833-vvlsqy36 109 5 towards towards IN cord-354833-vvlsqy36 109 6 a a DT cord-354833-vvlsqy36 109 7 formal formal JJ cord-354833-vvlsqy36 109 8 ontology ontology NN cord-354833-vvlsqy36 109 9 , , , cord-354833-vvlsqy36 109 10 these these DT cord-354833-vvlsqy36 109 11 elements element NNS cord-354833-vvlsqy36 109 12 are be VBP cord-354833-vvlsqy36 109 13 placed place VBN cord-354833-vvlsqy36 109 14 in in IN cord-354833-vvlsqy36 109 15 a a DT cord-354833-vvlsqy36 109 16 hierarchy hierarchy NN cord-354833-vvlsqy36 109 17 ( ( -LRB- cord-354833-vvlsqy36 109 18 simplified simplified JJ cord-354833-vvlsqy36 109 19 view view NN cord-354833-vvlsqy36 109 20 depicted depict VBN cord-354833-vvlsqy36 109 21 on on IN cord-354833-vvlsqy36 109 22 the the DT cord-354833-vvlsqy36 109 23 right right NN cord-354833-vvlsqy36 109 24 ) ) -RRB- cord-354833-vvlsqy36 109 25 , , , cord-354833-vvlsqy36 109 26 in in IN cord-354833-vvlsqy36 109 27 which which WDT cord-354833-vvlsqy36 109 28 relationships relationship NNS cord-354833-vvlsqy36 109 29 between between IN cord-354833-vvlsqy36 109 30 the the DT cord-354833-vvlsqy36 109 31 different different JJ cord-354833-vvlsqy36 109 32 classes class NNS cord-354833-vvlsqy36 109 33 are be VBP cord-354833-vvlsqy36 109 34 made make VBN cord-354833-vvlsqy36 109 35 explicit explicit JJ cord-354833-vvlsqy36 109 36 . . . cord-354833-vvlsqy36 110 1 For for IN cord-354833-vvlsqy36 110 2 example example NN cord-354833-vvlsqy36 110 3 , , , cord-354833-vvlsqy36 110 4 the the DT cord-354833-vvlsqy36 110 5 previously previously RB cord-354833-vvlsqy36 110 6 separate separate JJ cord-354833-vvlsqy36 110 7 and and CC cord-354833-vvlsqy36 110 8 unconnected unconnected JJ cord-354833-vvlsqy36 110 9 classes class NNS cord-354833-vvlsqy36 110 10 Antigen Antigen NNP cord-354833-vvlsqy36 110 11 , , , cord-354833-vvlsqy36 110 12 Immunogen Immunogen NNP cord-354833-vvlsqy36 110 13 and and CC cord-354833-vvlsqy36 110 14 Adjuvant Adjuvant NNP cord-354833-vvlsqy36 110 15 are be VBP cord-354833-vvlsqy36 110 16 now now RB cord-354833-vvlsqy36 110 17 recognized recognize VBN cord-354833-vvlsqy36 110 18 as as IN cord-354833-vvlsqy36 110 19 being be VBG cord-354833-vvlsqy36 110 20 objects object NNS cord-354833-vvlsqy36 110 21 ( ( -LRB- cord-354833-vvlsqy36 110 22 for for IN cord-354833-vvlsqy36 110 23 example example NN cord-354833-vvlsqy36 110 24 , , , cord-354833-vvlsqy36 110 25 Proteins Proteins NNP cord-354833-vvlsqy36 110 26 ) ) -RRB- cord-354833-vvlsqy36 110 27 , , , cord-354833-vvlsqy36 110 28 which which WDT cord-354833-vvlsqy36 110 29 participate participate VBP cord-354833-vvlsqy36 110 30 in in IN cord-354833-vvlsqy36 110 31 a a DT cord-354833-vvlsqy36 110 32 certain certain JJ cord-354833-vvlsqy36 110 33 role role NN cord-354833-vvlsqy36 110 34 ( ( -LRB- cord-354833-vvlsqy36 110 35 as as IN cord-354833-vvlsqy36 110 36 Immunogens Immunogens NNP cord-354833-vvlsqy36 110 37 ) ) -RRB- cord-354833-vvlsqy36 110 38 in in IN cord-354833-vvlsqy36 110 39 a a DT cord-354833-vvlsqy36 110 40 specific specific JJ cord-354833-vvlsqy36 110 41 process process NN cord-354833-vvlsqy36 110 42 ( ( -LRB- cord-354833-vvlsqy36 110 43 such such JJ cord-354833-vvlsqy36 110 44 as as IN cord-354833-vvlsqy36 110 45 Immunization Immunization NNP cord-354833-vvlsqy36 110 46 ) ) -RRB- cord-354833-vvlsqy36 110 47 . . . cord-354833-vvlsqy36 111 1 Compared compare VBN cord-354833-vvlsqy36 111 2 with with IN cord-354833-vvlsqy36 111 3 the the DT cord-354833-vvlsqy36 111 4 T t NN cord-354833-vvlsqy36 111 5 - - HYPH cord-354833-vvlsqy36 111 6 cell cell NN cord-354833-vvlsqy36 111 7 - - HYPH cord-354833-vvlsqy36 111 8 epitope epitope NN cord-354833-vvlsqy36 111 9 predictions prediction NNS cord-354833-vvlsqy36 111 10 , , , cord-354833-vvlsqy36 111 11 the the DT cord-354833-vvlsqy36 111 12 state state NN cord-354833-vvlsqy36 111 13 of of IN cord-354833-vvlsqy36 111 14 antibody antibody NN cord-354833-vvlsqy36 111 15 - - HYPH cord-354833-vvlsqy36 111 16 epitope epitope NN cord-354833-vvlsqy36 111 17 predictions prediction NNS cord-354833-vvlsqy36 111 18 is be VBZ cord-354833-vvlsqy36 111 19 widely widely RB cord-354833-vvlsqy36 111 20 considered consider VBN cord-354833-vvlsqy36 111 21 to to TO cord-354833-vvlsqy36 111 22 be be VB cord-354833-vvlsqy36 111 23 suboptimal suboptimal JJ cord-354833-vvlsqy36 111 24 29 29 CD cord-354833-vvlsqy36 111 25 . . . cord-354833-vvlsqy36 112 1 In in IN cord-354833-vvlsqy36 112 2 a a DT cord-354833-vvlsqy36 112 3 recent recent JJ cord-354833-vvlsqy36 112 4 workshop workshop NN cord-354833-vvlsqy36 112 5 sponsored sponsor VBN cord-354833-vvlsqy36 112 6 by by IN cord-354833-vvlsqy36 112 7 the the DT cord-354833-vvlsqy36 112 8 NIAID NIAID NNP cord-354833-vvlsqy36 112 9 that that WDT cord-354833-vvlsqy36 112 10 brought bring VBD cord-354833-vvlsqy36 112 11 together together RB cord-354833-vvlsqy36 112 12 many many JJ cord-354833-vvlsqy36 112 13 experts expert NNS cord-354833-vvlsqy36 112 14 from from IN cord-354833-vvlsqy36 112 15 the the DT cord-354833-vvlsqy36 112 16 antibody antibody NN cord-354833-vvlsqy36 112 17 - - HYPH cord-354833-vvlsqy36 112 18 epitope epitope NN cord-354833-vvlsqy36 112 19 - - HYPH cord-354833-vvlsqy36 112 20 prediction prediction NN cord-354833-vvlsqy36 112 21 community community NN cord-354833-vvlsqy36 112 22 , , , cord-354833-vvlsqy36 112 23 this this DT cord-354833-vvlsqy36 112 24 concern concern NN cord-354833-vvlsqy36 112 25 was be VBD cord-354833-vvlsqy36 112 26 widely widely RB cord-354833-vvlsqy36 112 27 shared share VBN cord-354833-vvlsqy36 112 28 , , , cord-354833-vvlsqy36 112 29 and and CC cord-354833-vvlsqy36 112 30 the the DT cord-354833-vvlsqy36 112 31 steps step NNS cord-354833-vvlsqy36 112 32 needed need VBD cord-354833-vvlsqy36 112 33 to to TO cord-354833-vvlsqy36 112 34 improve improve VB cord-354833-vvlsqy36 112 35 this this DT cord-354833-vvlsqy36 112 36 situation situation NN cord-354833-vvlsqy36 112 37 were be VBD cord-354833-vvlsqy36 112 38 discussed discuss VBN cord-354833-vvlsqy36 112 39 30 30 CD cord-354833-vvlsqy36 112 40 . . . cord-354833-vvlsqy36 113 1 There there EX cord-354833-vvlsqy36 113 2 was be VBD cord-354833-vvlsqy36 113 3 wide wide JJ cord-354833-vvlsqy36 113 4 agreement agreement NN cord-354833-vvlsqy36 113 5 that that WDT cord-354833-vvlsqy36 113 6 the the DT cord-354833-vvlsqy36 113 7 field field NN cord-354833-vvlsqy36 113 8 could could MD cord-354833-vvlsqy36 113 9 greatly greatly RB cord-354833-vvlsqy36 113 10 benefit benefit VB cord-354833-vvlsqy36 113 11 from from IN cord-354833-vvlsqy36 113 12 community community NN cord-354833-vvlsqy36 113 13 - - HYPH cord-354833-vvlsqy36 113 14 assembled assemble VBN cord-354833-vvlsqy36 113 15 datasets dataset NNS cord-354833-vvlsqy36 113 16 that that WDT cord-354833-vvlsqy36 113 17 clarify clarify VBP cord-354833-vvlsqy36 113 18 what what WDT cord-354833-vvlsqy36 113 19 types type NNS cord-354833-vvlsqy36 113 20 of of IN cord-354833-vvlsqy36 113 21 epitope epitope NN cord-354833-vvlsqy36 113 22 should should MD cord-354833-vvlsqy36 113 23 be be VB cord-354833-vvlsqy36 113 24 included include VBN cord-354833-vvlsqy36 113 25 in in IN cord-354833-vvlsqy36 113 26 an an DT cord-354833-vvlsqy36 113 27 evaluation evaluation NN cord-354833-vvlsqy36 113 28 and and CC cord-354833-vvlsqy36 113 29 that that IN cord-354833-vvlsqy36 113 30 this this DT cord-354833-vvlsqy36 113 31 should should MD cord-354833-vvlsqy36 113 32 be be VB cord-354833-vvlsqy36 113 33 dependent dependent JJ cord-354833-vvlsqy36 113 34 on on IN cord-354833-vvlsqy36 113 35 the the DT cord-354833-vvlsqy36 113 36 intended intend VBN cord-354833-vvlsqy36 113 37 use use NN cord-354833-vvlsqy36 113 38 of of IN cord-354833-vvlsqy36 113 39 a a DT cord-354833-vvlsqy36 113 40 prediction prediction NN cord-354833-vvlsqy36 113 41 . . . cord-354833-vvlsqy36 114 1 Similarly similarly RB cord-354833-vvlsqy36 114 2 , , , cord-354833-vvlsqy36 114 3 the the DT cord-354833-vvlsqy36 114 4 metrics metric NNS cord-354833-vvlsqy36 114 5 used use VBN cord-354833-vvlsqy36 114 6 to to TO cord-354833-vvlsqy36 114 7 quantify quantify VB cord-354833-vvlsqy36 114 8 the the DT cord-354833-vvlsqy36 114 9 success success NN cord-354833-vvlsqy36 114 10 of of IN cord-354833-vvlsqy36 114 11 predictions prediction NNS cord-354833-vvlsqy36 114 12 should should MD cord-354833-vvlsqy36 114 13 be be VB cord-354833-vvlsqy36 114 14 commonly commonly RB cord-354833-vvlsqy36 114 15 agreed agree VBN cord-354833-vvlsqy36 114 16 on on RP cord-354833-vvlsqy36 114 17 for for IN cord-354833-vvlsqy36 114 18 a a DT cord-354833-vvlsqy36 114 19 better well JJR cord-354833-vvlsqy36 114 20 comparison comparison NN cord-354833-vvlsqy36 114 21 between between IN cord-354833-vvlsqy36 114 22 different different JJ cord-354833-vvlsqy36 114 23 studies study NNS cord-354833-vvlsqy36 114 24 . . . cord-354833-vvlsqy36 115 1 This this DT cord-354833-vvlsqy36 115 2 effort effort NN cord-354833-vvlsqy36 115 3 to to TO cord-354833-vvlsqy36 115 4 establish establish VB cord-354833-vvlsqy36 115 5 community community NN cord-354833-vvlsqy36 115 6 - - HYPH cord-354833-vvlsqy36 115 7 accepted accept VBN cord-354833-vvlsqy36 115 8 datasets dataset NNS cord-354833-vvlsqy36 115 9 and and CC cord-354833-vvlsqy36 115 10 metrics metric NNS cord-354833-vvlsqy36 115 11 will will MD cord-354833-vvlsqy36 115 12 aid aid VB cord-354833-vvlsqy36 115 13 in in IN cord-354833-vvlsqy36 115 14 the the DT cord-354833-vvlsqy36 115 15 acceptance acceptance NN cord-354833-vvlsqy36 115 16 of of IN cord-354833-vvlsqy36 115 17 a a DT cord-354833-vvlsqy36 115 18 newly newly RB cord-354833-vvlsqy36 115 19 emerging emerge VBG cord-354833-vvlsqy36 115 20 second second JJ cord-354833-vvlsqy36 115 21 generation generation NN cord-354833-vvlsqy36 115 22 of of IN cord-354833-vvlsqy36 115 23 antibody antibody NN cord-354833-vvlsqy36 115 24 - - HYPH cord-354833-vvlsqy36 115 25 epitope epitope NN cord-354833-vvlsqy36 115 26 prediction prediction NN cord-354833-vvlsqy36 115 27 tools tool NNS cord-354833-vvlsqy36 115 28 , , , cord-354833-vvlsqy36 115 29 many many JJ cord-354833-vvlsqy36 115 30 of of IN cord-354833-vvlsqy36 115 31 which which WDT cord-354833-vvlsqy36 115 32 take take VBP cord-354833-vvlsqy36 115 33 advantage advantage NN cord-354833-vvlsqy36 115 34 of of IN cord-354833-vvlsqy36 115 35 the the DT cord-354833-vvlsqy36 115 36 three three CD cord-354833-vvlsqy36 115 37 - - HYPH cord-354833-vvlsqy36 115 38 dimensional dimensional JJ cord-354833-vvlsqy36 115 39 structures structure NNS cord-354833-vvlsqy36 115 40 that that WDT cord-354833-vvlsqy36 115 41 are be VBP cord-354833-vvlsqy36 115 42 available available JJ cord-354833-vvlsqy36 115 43 for for IN cord-354833-vvlsqy36 115 44 antibody antibody NN cord-354833-vvlsqy36 115 45 - - HYPH cord-354833-vvlsqy36 115 46 antigen antigen NN cord-354833-vvlsqy36 115 47 binding binding NN cord-354833-vvlsqy36 115 48 . . . cord-354833-vvlsqy36 116 1 Three three CD cord-354833-vvlsqy36 116 2 steps step NNS cord-354833-vvlsqy36 116 3 in in IN cord-354833-vvlsqy36 116 4 an an DT cord-354833-vvlsqy36 116 5 advanced advanced JJ cord-354833-vvlsqy36 116 6 query query NN cord-354833-vvlsqy36 116 7 for for IN cord-354833-vvlsqy36 116 8 B b NN cord-354833-vvlsqy36 116 9 - - HYPH cord-354833-vvlsqy36 116 10 cell cell NN cord-354833-vvlsqy36 116 11 epitopes epitope NNS cord-354833-vvlsqy36 116 12 are be VBP cord-354833-vvlsqy36 116 13 illustrated illustrate VBN cord-354833-vvlsqy36 116 14 . . . cord-354833-vvlsqy36 117 1 First first RB cord-354833-vvlsqy36 117 2 , , , cord-354833-vvlsqy36 117 3 criteria criterion NNS cord-354833-vvlsqy36 117 4 are be VBP cord-354833-vvlsqy36 117 5 specified specify VBN cord-354833-vvlsqy36 117 6 to to TO cord-354833-vvlsqy36 117 7 query query VB cord-354833-vvlsqy36 117 8 for for IN cord-354833-vvlsqy36 117 9 epitopes epitope NNS cord-354833-vvlsqy36 117 10 that that WDT cord-354833-vvlsqy36 117 11 are be VBP cord-354833-vvlsqy36 117 12 recognized recognize VBN cord-354833-vvlsqy36 117 13 in in IN cord-354833-vvlsqy36 117 14 mice mouse NNS cord-354833-vvlsqy36 117 15 , , , cord-354833-vvlsqy36 117 16 where where WRB cord-354833-vvlsqy36 117 17 the the DT cord-354833-vvlsqy36 117 18 immunogen immunogen NN cord-354833-vvlsqy36 117 19 applied apply VBD cord-354833-vvlsqy36 117 20 was be VBD cord-354833-vvlsqy36 117 21 the the DT cord-354833-vvlsqy36 117 22 epitope epitope NN cord-354833-vvlsqy36 117 23 source source NN cord-354833-vvlsqy36 117 24 species specie NNS cord-354833-vvlsqy36 117 25 and and CC cord-354833-vvlsqy36 117 26 the the DT cord-354833-vvlsqy36 117 27 species specie NNS cord-354833-vvlsqy36 117 28 is be VBZ cord-354833-vvlsqy36 117 29 selected select VBN cord-354833-vvlsqy36 117 30 to to TO cord-354833-vvlsqy36 117 31 be be VB cord-354833-vvlsqy36 117 32 severe severe JJ cord-354833-vvlsqy36 117 33 acute acute JJ cord-354833-vvlsqy36 117 34 respiratory respiratory JJ cord-354833-vvlsqy36 117 35 syndrome syndrome NN cord-354833-vvlsqy36 117 36 ( ( -LRB- cord-354833-vvlsqy36 117 37 SARS)-associated sars)-associated CD cord-354833-vvlsqy36 117 38 coronavirus coronavirus NN cord-354833-vvlsqy36 117 39 ( ( -LRB- cord-354833-vvlsqy36 117 40 a a NN cord-354833-vvlsqy36 117 41 ) ) -RRB- cord-354833-vvlsqy36 117 42 . . . cord-354833-vvlsqy36 118 1 On on IN cord-354833-vvlsqy36 118 2 submitting submit VBG cord-354833-vvlsqy36 118 3 this this DT cord-354833-vvlsqy36 118 4 query query NN cord-354833-vvlsqy36 118 5 , , , cord-354833-vvlsqy36 118 6 a a DT cord-354833-vvlsqy36 118 7 summary summary NN cord-354833-vvlsqy36 118 8 of of IN cord-354833-vvlsqy36 118 9 epitope epitope NN cord-354833-vvlsqy36 118 10 records record NNS cord-354833-vvlsqy36 118 11 matching match VBG cord-354833-vvlsqy36 118 12 these these DT cord-354833-vvlsqy36 118 13 criteria criterion NNS cord-354833-vvlsqy36 118 14 are be VBP cord-354833-vvlsqy36 118 15 displayed display VBN cord-354833-vvlsqy36 118 16 ( ( -LRB- cord-354833-vvlsqy36 118 17 b b NN cord-354833-vvlsqy36 118 18 ) ) -RRB- cord-354833-vvlsqy36 118 19 . . . cord-354833-vvlsqy36 119 1 This this DT cord-354833-vvlsqy36 119 2 includes include VBZ cord-354833-vvlsqy36 119 3 information information NN cord-354833-vvlsqy36 119 4 on on IN cord-354833-vvlsqy36 119 5 the the DT cord-354833-vvlsqy36 119 6 curated curate VBN cord-354833-vvlsqy36 119 7 reference reference NN cord-354833-vvlsqy36 119 8 , , , cord-354833-vvlsqy36 119 9 epitope epitope NN cord-354833-vvlsqy36 119 10 structure structure NN cord-354833-vvlsqy36 119 11 , , , cord-354833-vvlsqy36 119 12 epitope epitope NN cord-354833-vvlsqy36 119 13 source source NN cord-354833-vvlsqy36 119 14 , , , cord-354833-vvlsqy36 119 15 and and CC cord-354833-vvlsqy36 119 16 assay assay NN cord-354833-vvlsqy36 119 17 used use VBN cord-354833-vvlsqy36 119 18 . . . cord-354833-vvlsqy36 120 1 When when WRB cord-354833-vvlsqy36 120 2 choosing choose VBG cord-354833-vvlsqy36 120 3 the the DT cord-354833-vvlsqy36 120 4 ' ' `` cord-354833-vvlsqy36 120 5 Details detail NNS cord-354833-vvlsqy36 120 6 ' ' POS cord-354833-vvlsqy36 120 7 link link NN cord-354833-vvlsqy36 120 8 for for IN cord-354833-vvlsqy36 120 9 a a DT cord-354833-vvlsqy36 120 10 specific specific JJ cord-354833-vvlsqy36 120 11 epitope epitope NN cord-354833-vvlsqy36 120 12 , , , cord-354833-vvlsqy36 120 13 the the DT cord-354833-vvlsqy36 120 14 complete complete JJ cord-354833-vvlsqy36 120 15 curated curate VBN cord-354833-vvlsqy36 120 16 information information NN cord-354833-vvlsqy36 120 17 is be VBZ cord-354833-vvlsqy36 120 18 displayed display VBN cord-354833-vvlsqy36 120 19 ( ( -LRB- cord-354833-vvlsqy36 120 20 c c NN cord-354833-vvlsqy36 120 21 ) ) -RRB- cord-354833-vvlsqy36 120 22 . . . cord-354833-vvlsqy36 120 23 _SP cord-354833-vvlsqy36 121 1 After after IN cord-354833-vvlsqy36 121 2 curating curate VBG cord-354833-vvlsqy36 121 3 all all DT cord-354833-vvlsqy36 121 4 journal journal NN cord-354833-vvlsqy36 121 5 articles article NNS cord-354833-vvlsqy36 121 6 published publish VBN cord-354833-vvlsqy36 121 7 with with IN cord-354833-vvlsqy36 121 8 immune immune JJ cord-354833-vvlsqy36 121 9 epitope epitope NN cord-354833-vvlsqy36 121 10 information information NN cord-354833-vvlsqy36 121 11 , , , cord-354833-vvlsqy36 121 12 several several JJ cord-354833-vvlsqy36 121 13 summary summary NN cord-354833-vvlsqy36 121 14 analyses analysis NNS cord-354833-vvlsqy36 121 15 could could MD cord-354833-vvlsqy36 121 16 be be VB cord-354833-vvlsqy36 121 17 carried carry VBN cord-354833-vvlsqy36 121 18 out out RP cord-354833-vvlsqy36 121 19 . . . cord-354833-vvlsqy36 122 1 This this DT cord-354833-vvlsqy36 122 2 pie pie NN cord-354833-vvlsqy36 122 3 chart chart NN cord-354833-vvlsqy36 122 4 illustrates illustrate VBZ cord-354833-vvlsqy36 122 5 the the DT cord-354833-vvlsqy36 122 6 relative relative JJ cord-354833-vvlsqy36 122 7 number number NN cord-354833-vvlsqy36 122 8 of of IN cord-354833-vvlsqy36 122 9 antibody antibody NN cord-354833-vvlsqy36 122 10 and and CC cord-354833-vvlsqy36 122 11 T t NN cord-354833-vvlsqy36 122 12 - - HYPH cord-354833-vvlsqy36 122 13 cell cell NN cord-354833-vvlsqy36 122 14 epitopes epitope NNS cord-354833-vvlsqy36 122 15 identified identify VBN cord-354833-vvlsqy36 122 16 . . . cord-354833-vvlsqy36 123 1 Surprisingly surprisingly RB cord-354833-vvlsqy36 123 2 , , , cord-354833-vvlsqy36 123 3 although although IN cord-354833-vvlsqy36 123 4 protective protective JJ cord-354833-vvlsqy36 123 5 immunity immunity NN cord-354833-vvlsqy36 123 6 against against IN cord-354833-vvlsqy36 123 7 the the DT cord-354833-vvlsqy36 123 8 influenza influenza NN cord-354833-vvlsqy36 123 9 virus virus NN cord-354833-vvlsqy36 123 10 is be VBZ cord-354833-vvlsqy36 123 11 known know VBN cord-354833-vvlsqy36 123 12 to to TO cord-354833-vvlsqy36 123 13 be be VB cord-354833-vvlsqy36 123 14 largely largely RB cord-354833-vvlsqy36 123 15 mediated mediate VBN cord-354833-vvlsqy36 123 16 by by IN cord-354833-vvlsqy36 123 17 antibodies antibody NNS cord-354833-vvlsqy36 123 18 , , , cord-354833-vvlsqy36 123 19 this this DT cord-354833-vvlsqy36 123 20 chart chart NN cord-354833-vvlsqy36 123 21 reveals reveal VBZ cord-354833-vvlsqy36 123 22 that that IN cord-354833-vvlsqy36 123 23 much much RB cord-354833-vvlsqy36 123 24 more more JJR cord-354833-vvlsqy36 123 25 data data NN cord-354833-vvlsqy36 123 26 is be VBZ cord-354833-vvlsqy36 123 27 available available JJ cord-354833-vvlsqy36 123 28 on on IN cord-354833-vvlsqy36 123 29 T t NN cord-354833-vvlsqy36 123 30 - - HYPH cord-354833-vvlsqy36 123 31 cell cell NN cord-354833-vvlsqy36 123 32 epitopes epitope NNS cord-354833-vvlsqy36 123 33 for for IN cord-354833-vvlsqy36 123 34 this this DT cord-354833-vvlsqy36 123 35 virus virus NN cord-354833-vvlsqy36 123 36 . . . cord-354833-vvlsqy36 124 1 Figure figure NN cord-354833-vvlsqy36 124 2 3 3 CD cord-354833-vvlsqy36 124 3 | | NNS cord-354833-vvlsqy36 124 4 Homology homology NN cord-354833-vvlsqy36 124 5 mapping mapping NN cord-354833-vvlsqy36 124 6 of of IN cord-354833-vvlsqy36 124 7 an an DT cord-354833-vvlsqy36 124 8 epitope epitope NN cord-354833-vvlsqy36 124 9 into into IN cord-354833-vvlsqy36 124 10 its -PRON- PRP$ cord-354833-vvlsqy36 124 11 three three CD cord-354833-vvlsqy36 124 12 - - HYPH cord-354833-vvlsqy36 124 13 dimensional dimensional JJ cord-354833-vvlsqy36 124 14 source source NN cord-354833-vvlsqy36 124 15 protein protein NN cord-354833-vvlsqy36 124 16 structure structure NN cord-354833-vvlsqy36 124 17 . . . cord-354833-vvlsqy36 125 1 For for IN cord-354833-vvlsqy36 125 2 a a DT cord-354833-vvlsqy36 125 3 given give VBN cord-354833-vvlsqy36 125 4 epitope epitope NN cord-354833-vvlsqy36 125 5 and and CC cord-354833-vvlsqy36 125 6 its -PRON- PRP$ cord-354833-vvlsqy36 125 7 source source NN cord-354833-vvlsqy36 125 8 protein protein NN cord-354833-vvlsqy36 125 9 , , , cord-354833-vvlsqy36 125 10 the the DT cord-354833-vvlsqy36 125 11 homology homology NN cord-354833-vvlsqy36 125 12 tool tool NN cord-354833-vvlsqy36 125 13 of of IN cord-354833-vvlsqy36 125 14 the the DT cord-354833-vvlsqy36 125 15 Immune Immune NNP cord-354833-vvlsqy36 125 16 Epitope Epitope NNP cord-354833-vvlsqy36 125 17 Database Database NNP cord-354833-vvlsqy36 125 18 and and CC cord-354833-vvlsqy36 125 19 Analysis Analysis NNP cord-354833-vvlsqy36 125 20 Resource Resource NNP cord-354833-vvlsqy36 125 21 identifies identify VBZ cord-354833-vvlsqy36 125 22 homologous homologous JJ cord-354833-vvlsqy36 125 23 proteins protein NNS cord-354833-vvlsqy36 125 24 with with IN cord-354833-vvlsqy36 125 25 known know VBN cord-354833-vvlsqy36 125 26 three three CD cord-354833-vvlsqy36 125 27 - - HYPH cord-354833-vvlsqy36 125 28 dimensional dimensional JJ cord-354833-vvlsqy36 125 29 structures structure NNS cord-354833-vvlsqy36 125 30 , , , cord-354833-vvlsqy36 125 31 and and CC cord-354833-vvlsqy36 125 32 maps map VBZ cord-354833-vvlsqy36 125 33 the the DT cord-354833-vvlsqy36 125 34 location location NN cord-354833-vvlsqy36 125 35 of of IN cord-354833-vvlsqy36 125 36 epitopes epitope NNS cord-354833-vvlsqy36 125 37 in in IN cord-354833-vvlsqy36 125 38 these these DT cord-354833-vvlsqy36 125 39 structures structure NNS cord-354833-vvlsqy36 125 40 . . . cord-354833-vvlsqy36 126 1 In in IN cord-354833-vvlsqy36 126 2 this this DT cord-354833-vvlsqy36 126 3 example example NN cord-354833-vvlsqy36 126 4 , , , cord-354833-vvlsqy36 126 5 the the DT cord-354833-vvlsqy36 126 6 peptide peptide NN cord-354833-vvlsqy36 126 7 NTNSGPDDQIGYYRRATR NTNSGPDDQIGYYRRATR NNP cord-354833-vvlsqy36 126 8 ( ( -LRB- cord-354833-vvlsqy36 126 9 shown show VBN cord-354833-vvlsqy36 126 10 in in IN cord-354833-vvlsqy36 126 11 blue blue JJ cord-354833-vvlsqy36 126 12 ) ) -RRB- cord-354833-vvlsqy36 126 13 , , , cord-354833-vvlsqy36 126 14 which which WDT cord-354833-vvlsqy36 126 15 is be VBZ cord-354833-vvlsqy36 126 16 recognized recognize VBN cord-354833-vvlsqy36 126 17 by by IN cord-354833-vvlsqy36 126 18 antibodies antibody NNS cord-354833-vvlsqy36 126 19 from from IN cord-354833-vvlsqy36 126 20 mice mouse NNS cord-354833-vvlsqy36 126 21 immunized immunize VBN cord-354833-vvlsqy36 126 22 with with IN cord-354833-vvlsqy36 126 23 inactivated inactivate VBN cord-354833-vvlsqy36 126 24 severe severe JJ cord-354833-vvlsqy36 126 25 acute acute JJ cord-354833-vvlsqy36 126 26 respiratory respiratory JJ cord-354833-vvlsqy36 126 27 syndrome syndrome NN cord-354833-vvlsqy36 126 28 ( ( -LRB- cord-354833-vvlsqy36 126 29 SARS)-associated sars)-associated CD cord-354833-vvlsqy36 126 30 coronavirus coronavirus NN cord-354833-vvlsqy36 126 31 ( ( -LRB- cord-354833-vvlsqy36 126 32 SARS SARS NNP cord-354833-vvlsqy36 126 33 - - HYPH cord-354833-vvlsqy36 126 34 CoV CoV NNP cord-354833-vvlsqy36 126 35 ) ) -RRB- cord-354833-vvlsqy36 126 36 34 34 CD cord-354833-vvlsqy36 126 37 , , , cord-354833-vvlsqy36 126 38 is be VBZ cord-354833-vvlsqy36 126 39 mapped map VBN cord-354833-vvlsqy36 126 40 to to IN cord-354833-vvlsqy36 126 41 an an DT cord-354833-vvlsqy36 126 42 X x NN cord-354833-vvlsqy36 126 43 - - NN cord-354833-vvlsqy36 126 44 ray ray JJ cord-354833-vvlsqy36 126 45 structure structure NN cord-354833-vvlsqy36 126 46 of of IN cord-354833-vvlsqy36 126 47 the the DT cord-354833-vvlsqy36 126 48 SARS SARS NNP cord-354833-vvlsqy36 126 49 - - HYPH cord-354833-vvlsqy36 126 50 CoV CoV NNP cord-354833-vvlsqy36 126 51 nucleocapsid nucleocapsid NNP cord-354833-vvlsqy36 126 52 protein protein NNP cord-354833-vvlsqy36 126 53 . . . cord-354833-vvlsqy36 127 1 The the DT cord-354833-vvlsqy36 127 2 arrow arrow NN cord-354833-vvlsqy36 127 3 indicates indicate VBZ cord-354833-vvlsqy36 127 4 a a DT cord-354833-vvlsqy36 127 5 section section NN cord-354833-vvlsqy36 127 6 of of IN cord-354833-vvlsqy36 127 7 the the DT cord-354833-vvlsqy36 127 8 epitope epitope NN cord-354833-vvlsqy36 127 9 that that WDT cord-354833-vvlsqy36 127 10 is be VBZ cord-354833-vvlsqy36 127 11 exposed expose VBN cord-354833-vvlsqy36 127 12 at at IN cord-354833-vvlsqy36 127 13 the the DT cord-354833-vvlsqy36 127 14 surface surface NN cord-354833-vvlsqy36 127 15 of of IN cord-354833-vvlsqy36 127 16 the the DT cord-354833-vvlsqy36 127 17 virus virus NN cord-354833-vvlsqy36 127 18 , , , cord-354833-vvlsqy36 127 19 making make VBG cord-354833-vvlsqy36 127 20 it -PRON- PRP cord-354833-vvlsqy36 127 21 a a DT cord-354833-vvlsqy36 127 22 candidate candidate NN cord-354833-vvlsqy36 127 23 binding bind VBG cord-354833-vvlsqy36 127 24 site site NN cord-354833-vvlsqy36 127 25 for for IN cord-354833-vvlsqy36 127 26 the the DT cord-354833-vvlsqy36 127 27 antibody antibody NN cord-354833-vvlsqy36 127 28 in in IN cord-354833-vvlsqy36 127 29 the the DT cord-354833-vvlsqy36 127 30 native native JJ cord-354833-vvlsqy36 127 31 protein protein NN cord-354833-vvlsqy36 127 32 structure structure NN cord-354833-vvlsqy36 127 33 . . . cord-354833-vvlsqy36 128 1 the the DT cord-354833-vvlsqy36 128 2 epitope epitope NN cord-354833-vvlsqy36 128 3 analytical analytical JJ cord-354833-vvlsqy36 128 4 tools tool NNS cord-354833-vvlsqy36 128 5 provided provide VBN cord-354833-vvlsqy36 128 6 by by IN cord-354833-vvlsqy36 128 7 the the DT cord-354833-vvlsqy36 128 8 IEDB IEDB NNP cord-354833-vvlsqy36 128 9 , , , cord-354833-vvlsqy36 128 10 the the DT cord-354833-vvlsqy36 128 11 degree degree NN cord-354833-vvlsqy36 128 12 of of IN cord-354833-vvlsqy36 128 13 conservation conservation NN cord-354833-vvlsqy36 128 14 of of IN cord-354833-vvlsqy36 128 15 various various JJ cord-354833-vvlsqy36 128 16 epitopes epitope NNS cord-354833-vvlsqy36 128 17 in in IN cord-354833-vvlsqy36 128 18 a a DT cord-354833-vvlsqy36 128 19 representative representative JJ cord-354833-vvlsqy36 128 20 set set NN cord-354833-vvlsqy36 128 21 of of IN cord-354833-vvlsqy36 128 22 influenzavirus influenzavirus NN cord-354833-vvlsqy36 128 23 sequences sequence NNS cord-354833-vvlsqy36 128 24 was be VBD cord-354833-vvlsqy36 128 25 determined determine VBN cord-354833-vvlsqy36 128 26 . . . cord-354833-vvlsqy36 129 1 Several several JJ cord-354833-vvlsqy36 129 2 interesting interesting JJ cord-354833-vvlsqy36 129 3 , , , cord-354833-vvlsqy36 129 4 highly highly RB cord-354833-vvlsqy36 129 5 conserved conserve VBN cord-354833-vvlsqy36 129 6 epitopes epitope NNS cord-354833-vvlsqy36 129 7 were be VBD cord-354833-vvlsqy36 129 8 identified identify VBN cord-354833-vvlsqy36 129 9 by by IN cord-354833-vvlsqy36 129 10 this this DT cord-354833-vvlsqy36 129 11 analysis analysis NN cord-354833-vvlsqy36 129 12 . . . cord-354833-vvlsqy36 130 1 At at IN cord-354833-vvlsqy36 130 2 the the DT cord-354833-vvlsqy36 130 3 same same JJ cord-354833-vvlsqy36 130 4 time time NN cord-354833-vvlsqy36 130 5 , , , cord-354833-vvlsqy36 130 6 the the DT cord-354833-vvlsqy36 130 7 analysis analysis NN cord-354833-vvlsqy36 130 8 can can MD cord-354833-vvlsqy36 130 9 be be VB cord-354833-vvlsqy36 130 10 used use VBN cord-354833-vvlsqy36 130 11 to to TO cord-354833-vvlsqy36 130 12 probe probe VB cord-354833-vvlsqy36 130 13 for for IN cord-354833-vvlsqy36 130 14 potential potential JJ cord-354833-vvlsqy36 130 15 gaps gap NNS cord-354833-vvlsqy36 130 16 in in IN cord-354833-vvlsqy36 130 17 our -PRON- PRP$ cord-354833-vvlsqy36 130 18 knowledge knowledge NN cord-354833-vvlsqy36 130 19 relating relate VBG cord-354833-vvlsqy36 130 20 to to IN cord-354833-vvlsqy36 130 21 influenza influenza NN cord-354833-vvlsqy36 130 22 - - HYPH cord-354833-vvlsqy36 130 23 virus virus NN cord-354833-vvlsqy36 130 24 epitopes epitope NNS cord-354833-vvlsqy36 130 25 . . . cord-354833-vvlsqy36 131 1 Indeed indeed RB cord-354833-vvlsqy36 131 2 , , , cord-354833-vvlsqy36 131 3 significant significant JJ cord-354833-vvlsqy36 131 4 gaps gap NNS cord-354833-vvlsqy36 131 5 in in IN cord-354833-vvlsqy36 131 6 the the DT cord-354833-vvlsqy36 131 7 current current JJ cord-354833-vvlsqy36 131 8 knowledge knowledge NN cord-354833-vvlsqy36 131 9 were be VBD cord-354833-vvlsqy36 131 10 revealed reveal VBN cord-354833-vvlsqy36 131 11 , , , cord-354833-vvlsqy36 131 12 including include VBG cord-354833-vvlsqy36 131 13 a a DT cord-354833-vvlsqy36 131 14 paucity paucity NN cord-354833-vvlsqy36 131 15 of of IN cord-354833-vvlsqy36 131 16 antibody antibody NN cord-354833-vvlsqy36 131 17 epitopes epitope NNS cord-354833-vvlsqy36 131 18 in in IN cord-354833-vvlsqy36 131 19 comparison comparison NN cord-354833-vvlsqy36 131 20 to to IN cord-354833-vvlsqy36 131 21 T t NN cord-354833-vvlsqy36 131 22 - - HYPH cord-354833-vvlsqy36 131 23 cell cell NN cord-354833-vvlsqy36 131 24 epitopes epitope NNS cord-354833-vvlsqy36 131 25 ( ( -LRB- cord-354833-vvlsqy36 131 26 FIG FIG NNP cord-354833-vvlsqy36 131 27 . . . cord-354833-vvlsqy36 131 28 4 4 LS cord-354833-vvlsqy36 131 29 ) ) -RRB- cord-354833-vvlsqy36 131 30 , , , cord-354833-vvlsqy36 131 31 a a DT cord-354833-vvlsqy36 131 32 limited limited JJ cord-354833-vvlsqy36 131 33 number number NN cord-354833-vvlsqy36 131 34 of of IN cord-354833-vvlsqy36 131 35 epitopes epitope NNS cord-354833-vvlsqy36 131 36 reported report VBN cord-354833-vvlsqy36 131 37 for for IN cord-354833-vvlsqy36 131 38 avian avian JJ cord-354833-vvlsqy36 131 39 influenza influenza NN cord-354833-vvlsqy36 131 40 virus virus NN cord-354833-vvlsqy36 131 41 strains strain NNS cord-354833-vvlsqy36 131 42 and/or and/or CC cord-354833-vvlsqy36 131 43 subtypes subtype NNS cord-354833-vvlsqy36 131 44 , , , cord-354833-vvlsqy36 131 45 and and CC cord-354833-vvlsqy36 131 46 a a DT cord-354833-vvlsqy36 131 47 limited limited JJ cord-354833-vvlsqy36 131 48 number number NN cord-354833-vvlsqy36 131 49 of of IN cord-354833-vvlsqy36 131 50 epitopes epitope NNS cord-354833-vvlsqy36 131 51 reported report VBN cord-354833-vvlsqy36 131 52 from from IN cord-354833-vvlsqy36 131 53 proteins protein NNS cord-354833-vvlsqy36 131 54 other other JJ cord-354833-vvlsqy36 131 55 than than IN cord-354833-vvlsqy36 131 56 haemagglutinin haemagglutinin NNP cord-354833-vvlsqy36 131 57 and and CC cord-354833-vvlsqy36 131 58 nucleocapsid nucleocapsid NNP cord-354833-vvlsqy36 131 59 protein protein NN cord-354833-vvlsqy36 131 60 . . . cord-354833-vvlsqy36 132 1 These these DT cord-354833-vvlsqy36 132 2 gaps gap NNS cord-354833-vvlsqy36 132 3 in in IN cord-354833-vvlsqy36 132 4 our -PRON- PRP$ cord-354833-vvlsqy36 132 5 collective collective JJ cord-354833-vvlsqy36 132 6 knowledge knowledge NN cord-354833-vvlsqy36 132 7 should should MD cord-354833-vvlsqy36 132 8 inspire inspire VB cord-354833-vvlsqy36 132 9 directions direction NNS cord-354833-vvlsqy36 132 10 for for IN cord-354833-vvlsqy36 132 11 further further JJ cord-354833-vvlsqy36 132 12 study study NN cord-354833-vvlsqy36 132 13 of of IN cord-354833-vvlsqy36 132 14 immunity immunity NN cord-354833-vvlsqy36 132 15 against against IN cord-354833-vvlsqy36 132 16 the the DT cord-354833-vvlsqy36 132 17 influenza influenza NN cord-354833-vvlsqy36 132 18 A a DT cord-354833-vvlsqy36 132 19 virus virus NN cord-354833-vvlsqy36 132 20 . . . cord-354833-vvlsqy36 133 1 In in IN cord-354833-vvlsqy36 133 2 this this DT cord-354833-vvlsqy36 133 3 Innovation Innovation NNP cord-354833-vvlsqy36 133 4 article article NN cord-354833-vvlsqy36 133 5 , , , cord-354833-vvlsqy36 133 6 we -PRON- PRP cord-354833-vvlsqy36 133 7 present present VBP cord-354833-vvlsqy36 133 8 the the DT cord-354833-vvlsqy36 133 9 experience experience NN cord-354833-vvlsqy36 133 10 gained gain VBN cord-354833-vvlsqy36 133 11 so so RB cord-354833-vvlsqy36 133 12 far far RB cord-354833-vvlsqy36 133 13 in in IN cord-354833-vvlsqy36 133 14 a a DT cord-354833-vvlsqy36 133 15 cutting cutting JJ cord-354833-vvlsqy36 133 16 edge edge NN cord-354833-vvlsqy36 133 17 project project NN cord-354833-vvlsqy36 133 18 , , , cord-354833-vvlsqy36 133 19 which which WDT cord-354833-vvlsqy36 133 20 involves involve VBZ cord-354833-vvlsqy36 133 21 the the DT cord-354833-vvlsqy36 133 22 extraction extraction NN cord-354833-vvlsqy36 133 23 of of IN cord-354833-vvlsqy36 133 24 complex complex JJ cord-354833-vvlsqy36 133 25 immunological immunological JJ cord-354833-vvlsqy36 133 26 data datum NNS cord-354833-vvlsqy36 133 27 from from IN cord-354833-vvlsqy36 133 28 the the DT cord-354833-vvlsqy36 133 29 literature literature NN cord-354833-vvlsqy36 133 30 , , , cord-354833-vvlsqy36 133 31 making make VBG cord-354833-vvlsqy36 133 32 it -PRON- PRP cord-354833-vvlsqy36 133 33 available available JJ cord-354833-vvlsqy36 133 34 to to IN cord-354833-vvlsqy36 133 35 the the DT cord-354833-vvlsqy36 133 36 scientific scientific JJ cord-354833-vvlsqy36 133 37 community community NN cord-354833-vvlsqy36 133 38 and and CC cord-354833-vvlsqy36 133 39 integrating integrate VBG cord-354833-vvlsqy36 133 40 it -PRON- PRP cord-354833-vvlsqy36 133 41 in in IN cord-354833-vvlsqy36 133 42 the the DT cord-354833-vvlsqy36 133 43 emerging emerge VBG cord-354833-vvlsqy36 133 44 web web NN cord-354833-vvlsqy36 133 45 of of IN cord-354833-vvlsqy36 133 46 biomedical biomedical JJ cord-354833-vvlsqy36 133 47 knowledge knowledge NN cord-354833-vvlsqy36 133 48 resources resource NNS cord-354833-vvlsqy36 133 49 . . . cord-354833-vvlsqy36 134 1 The the DT cord-354833-vvlsqy36 134 2 issues issue NNS cord-354833-vvlsqy36 134 3 and and CC cord-354833-vvlsqy36 134 4 solutions solution NNS cord-354833-vvlsqy36 134 5 to to IN cord-354833-vvlsqy36 134 6 the the DT cord-354833-vvlsqy36 134 7 challenges challenge NNS cord-354833-vvlsqy36 134 8 that that WDT cord-354833-vvlsqy36 134 9 have have VBP cord-354833-vvlsqy36 134 10 been be VBN cord-354833-vvlsqy36 134 11 encountered encounter VBN cord-354833-vvlsqy36 134 12 in in IN cord-354833-vvlsqy36 134 13 the the DT cord-354833-vvlsqy36 134 14 development development NN cord-354833-vvlsqy36 134 15 of of IN cord-354833-vvlsqy36 134 16 this this DT cord-354833-vvlsqy36 134 17 project project NN cord-354833-vvlsqy36 134 18 are be VBP cord-354833-vvlsqy36 134 19 of of IN cord-354833-vvlsqy36 134 20 relevance relevance NN cord-354833-vvlsqy36 134 21 in in IN cord-354833-vvlsqy36 134 22 the the DT cord-354833-vvlsqy36 134 23 context context NN cord-354833-vvlsqy36 134 24 of of IN cord-354833-vvlsqy36 134 25 the the DT cord-354833-vvlsqy36 134 26 general general JJ cord-354833-vvlsqy36 134 27 trend trend NN cord-354833-vvlsqy36 134 28 of of IN cord-354833-vvlsqy36 134 29 initiatives initiative NNS cord-354833-vvlsqy36 134 30 that that WDT cord-354833-vvlsqy36 134 31 are be VBP cord-354833-vvlsqy36 134 32 aimed aim VBN cord-354833-vvlsqy36 134 33 at at IN cord-354833-vvlsqy36 134 34 collecting collect VBG cord-354833-vvlsqy36 134 35 and and CC cord-354833-vvlsqy36 134 36 displaying display VBG cord-354833-vvlsqy36 134 37 large large JJ cord-354833-vvlsqy36 134 38 amounts amount NNS cord-354833-vvlsqy36 134 39 of of IN cord-354833-vvlsqy36 134 40 data datum NNS cord-354833-vvlsqy36 134 41 of of IN cord-354833-vvlsqy36 134 42 genomic genomic JJ cord-354833-vvlsqy36 134 43 and and CC cord-354833-vvlsqy36 134 44 proteomic proteomic JJ cord-354833-vvlsqy36 134 45 origin origin NN cord-354833-vvlsqy36 134 46 , , , cord-354833-vvlsqy36 134 47 and and CC cord-354833-vvlsqy36 134 48 in in IN cord-354833-vvlsqy36 134 49 the the DT cord-354833-vvlsqy36 134 50 context context NN cord-354833-vvlsqy36 134 51 of of IN cord-354833-vvlsqy36 134 52 host host NN cord-354833-vvlsqy36 134 53 - - HYPH cord-354833-vvlsqy36 134 54 pathogen pathogen NN cord-354833-vvlsqy36 134 55 interactions interaction NNS cord-354833-vvlsqy36 134 56 in in IN cord-354833-vvlsqy36 134 57 general general JJ cord-354833-vvlsqy36 134 58 . . . cord-354833-vvlsqy36 135 1 The the DT cord-354833-vvlsqy36 135 2 initial initial JJ cord-354833-vvlsqy36 135 3 phase phase NN cord-354833-vvlsqy36 135 4 of of IN cord-354833-vvlsqy36 135 5 building build VBG cord-354833-vvlsqy36 135 6 and and CC cord-354833-vvlsqy36 135 7 starting start VBG cord-354833-vvlsqy36 135 8 Additional additional JJ cord-354833-vvlsqy36 135 9 tools tool NNS cord-354833-vvlsqy36 135 10 are be VBP cord-354833-vvlsqy36 135 11 provided provide VBN cord-354833-vvlsqy36 135 12 to to TO cord-354833-vvlsqy36 135 13 analyse analyse VB cord-354833-vvlsqy36 135 14 already already RB cord-354833-vvlsqy36 135 15 - - HYPH cord-354833-vvlsqy36 135 16 identified identify VBN cord-354833-vvlsqy36 135 17 responses response NNS cord-354833-vvlsqy36 135 18 . . . cord-354833-vvlsqy36 136 1 The the DT cord-354833-vvlsqy36 136 2 conservancy conservancy NN cord-354833-vvlsqy36 136 3 tool tool NN cord-354833-vvlsqy36 136 4 ( ( -LRB- cord-354833-vvlsqy36 136 5 Epitope Epitope NNP cord-354833-vvlsqy36 136 6 Conservancy Conservancy NNP cord-354833-vvlsqy36 136 7 Analysis Analysis NNP cord-354833-vvlsqy36 136 8 ) ) -RRB- cord-354833-vvlsqy36 136 9 of of IN cord-354833-vvlsqy36 136 10 the the DT cord-354833-vvlsqy36 136 11 IEDB IEDB NNP cord-354833-vvlsqy36 136 12 calculates calculate VBZ cord-354833-vvlsqy36 136 13 the the DT cord-354833-vvlsqy36 136 14 level level NN cord-354833-vvlsqy36 136 15 of of IN cord-354833-vvlsqy36 136 16 sequence sequence NN cord-354833-vvlsqy36 136 17 identity identity NN cord-354833-vvlsqy36 136 18 with with IN cord-354833-vvlsqy36 136 19 which which WDT cord-354833-vvlsqy36 136 20 a a DT cord-354833-vvlsqy36 136 21 set set NN cord-354833-vvlsqy36 136 22 of of IN cord-354833-vvlsqy36 136 23 epitopes epitope NNS cord-354833-vvlsqy36 136 24 occurs occur VBZ cord-354833-vvlsqy36 136 25 across across IN cord-354833-vvlsqy36 136 26 different different JJ cord-354833-vvlsqy36 136 27 strains strain NNS cord-354833-vvlsqy36 136 28 of of IN cord-354833-vvlsqy36 136 29 a a DT cord-354833-vvlsqy36 136 30 pathogen pathogen NN cord-354833-vvlsqy36 136 31 . . . cord-354833-vvlsqy36 137 1 The the DT cord-354833-vvlsqy36 137 2 population population NN cord-354833-vvlsqy36 137 3 - - HYPH cord-354833-vvlsqy36 137 4 coverage coverage NN cord-354833-vvlsqy36 137 5 tool tool NN cord-354833-vvlsqy36 137 6 ( ( -LRB- cord-354833-vvlsqy36 137 7 Population Population NNP cord-354833-vvlsqy36 137 8 Coverage Coverage NNP cord-354833-vvlsqy36 137 9 Calculation Calculation NNP cord-354833-vvlsqy36 137 10 ) ) -RRB- cord-354833-vvlsqy36 137 11 estimates estimate VBZ cord-354833-vvlsqy36 137 12 the the DT cord-354833-vvlsqy36 137 13 frequencies frequency NNS cord-354833-vvlsqy36 137 14 of of IN cord-354833-vvlsqy36 137 15 responses response NNS cord-354833-vvlsqy36 137 16 to to IN cord-354833-vvlsqy36 137 17 a a DT cord-354833-vvlsqy36 137 18 set set NN cord-354833-vvlsqy36 137 19 of of IN cord-354833-vvlsqy36 137 20 T t NN cord-354833-vvlsqy36 137 21 - - HYPH cord-354833-vvlsqy36 137 22 cell cell NN cord-354833-vvlsqy36 137 23 epitopes epitope NNS cord-354833-vvlsqy36 137 24 with with IN cord-354833-vvlsqy36 137 25 known know VBN cord-354833-vvlsqy36 137 26 MHC MHC NNP cord-354833-vvlsqy36 137 27 restrictions restriction NNS cord-354833-vvlsqy36 137 28 in in IN cord-354833-vvlsqy36 137 29 different different JJ cord-354833-vvlsqy36 137 30 sets set NNS cord-354833-vvlsqy36 137 31 of of IN cord-354833-vvlsqy36 137 32 populations population NNS cord-354833-vvlsqy36 137 33 with with IN cord-354833-vvlsqy36 137 34 known know VBN cord-354833-vvlsqy36 137 35 MHC MHC NNP cord-354833-vvlsqy36 137 36 allele allele NN cord-354833-vvlsqy36 137 37 frequencies frequency NNS cord-354833-vvlsqy36 137 38 31 31 CD cord-354833-vvlsqy36 137 39 . . . cord-354833-vvlsqy36 138 1 Finally finally RB cord-354833-vvlsqy36 138 2 , , , cord-354833-vvlsqy36 138 3 the the DT cord-354833-vvlsqy36 138 4 epitope epitope NN cord-354833-vvlsqy36 138 5 - - HYPH cord-354833-vvlsqy36 138 6 homology homology NN cord-354833-vvlsqy36 138 7 mapping mapping NN cord-354833-vvlsqy36 138 8 tool tool NN cord-354833-vvlsqy36 138 9 ( ( -LRB- cord-354833-vvlsqy36 138 10 Homology Homology NNP cord-354833-vvlsqy36 138 11 Mapping Mapping NNP cord-354833-vvlsqy36 138 12 ) ) -RRB- cord-354833-vvlsqy36 138 13 visualizes visualize VBZ cord-354833-vvlsqy36 138 14 the the DT cord-354833-vvlsqy36 138 15 location location NN cord-354833-vvlsqy36 138 16 of of IN cord-354833-vvlsqy36 138 17 epitopes epitope NNS cord-354833-vvlsqy36 138 18 within within IN cord-354833-vvlsqy36 138 19 the the DT cord-354833-vvlsqy36 138 20 threedimensional threedimensional JJ cord-354833-vvlsqy36 138 21 structure structure NN cord-354833-vvlsqy36 138 22 of of IN cord-354833-vvlsqy36 138 23 their -PRON- PRP$ cord-354833-vvlsqy36 138 24 source source NN cord-354833-vvlsqy36 138 25 antigen antigen NN cord-354833-vvlsqy36 138 26 using use VBG cord-354833-vvlsqy36 138 27 a a DT cord-354833-vvlsqy36 138 28 customized customize VBN cord-354833-vvlsqy36 138 29 epitope epitope NN cord-354833-vvlsqy36 138 30 viewer viewer NN cord-354833-vvlsqy36 138 31 32 32 CD cord-354833-vvlsqy36 138 32 . . . cord-354833-vvlsqy36 139 1 This this DT cord-354833-vvlsqy36 139 2 mapping mapping NN cord-354833-vvlsqy36 139 3 is be VBZ cord-354833-vvlsqy36 139 4 done do VBN cord-354833-vvlsqy36 139 5 through through IN cord-354833-vvlsqy36 139 6 a a DT cord-354833-vvlsqy36 139 7 screening screening NN cord-354833-vvlsqy36 139 8 of of IN cord-354833-vvlsqy36 139 9 available available JJ cord-354833-vvlsqy36 139 10 structures structure NNS cord-354833-vvlsqy36 139 11 in in IN cord-354833-vvlsqy36 139 12 the the DT cord-354833-vvlsqy36 139 13 PDB PDB NNP cord-354833-vvlsqy36 139 14 , , , cord-354833-vvlsqy36 139 15 from from IN cord-354833-vvlsqy36 139 16 which which WDT cord-354833-vvlsqy36 139 17 proteins protein NNS cord-354833-vvlsqy36 139 18 are be VBP cord-354833-vvlsqy36 139 19 selected select VBN cord-354833-vvlsqy36 139 20 that that IN cord-354833-vvlsqy36 139 21 closely closely RB cord-354833-vvlsqy36 139 22 resemble resemble VB cord-354833-vvlsqy36 139 23 the the DT cord-354833-vvlsqy36 139 24 epitope epitope NN cord-354833-vvlsqy36 139 25 source source NN cord-354833-vvlsqy36 139 26 antigen antigen NN cord-354833-vvlsqy36 139 27 and and CC cord-354833-vvlsqy36 139 28 specifically specifically RB cord-354833-vvlsqy36 139 29 conserve conserve VB cord-354833-vvlsqy36 139 30 the the DT cord-354833-vvlsqy36 139 31 sequence sequence NN cord-354833-vvlsqy36 139 32 of of IN cord-354833-vvlsqy36 139 33 the the DT cord-354833-vvlsqy36 139 34 epitope epitope NN cord-354833-vvlsqy36 139 35 itself -PRON- PRP cord-354833-vvlsqy36 139 36 ( ( -LRB- cord-354833-vvlsqy36 139 37 FIG fig NN cord-354833-vvlsqy36 139 38 . . . cord-354833-vvlsqy36 139 39 3 3 CD cord-354833-vvlsqy36 139 40 ) ) -RRB- cord-354833-vvlsqy36 139 41 . . . cord-354833-vvlsqy36 140 1 As as IN cord-354833-vvlsqy36 140 2 an an DT cord-354833-vvlsqy36 140 3 illustration illustration NN cord-354833-vvlsqy36 140 4 of of IN cord-354833-vvlsqy36 140 5 the the DT cord-354833-vvlsqy36 140 6 usefulness usefulness NN cord-354833-vvlsqy36 140 7 and and CC cord-354833-vvlsqy36 140 8 power power NN cord-354833-vvlsqy36 140 9 of of IN cord-354833-vvlsqy36 140 10 the the DT cord-354833-vvlsqy36 140 11 compilation compilation NN cord-354833-vvlsqy36 140 12 of of IN cord-354833-vvlsqy36 140 13 immuneepitope immuneepitope NN cord-354833-vvlsqy36 140 14 - - HYPH cord-354833-vvlsqy36 140 15 related relate VBN cord-354833-vvlsqy36 140 16 data datum NNS cord-354833-vvlsqy36 140 17 , , , cord-354833-vvlsqy36 140 18 we -PRON- PRP cord-354833-vvlsqy36 140 19 have have VBP cord-354833-vvlsqy36 140 20 recently recently RB cord-354833-vvlsqy36 140 21 curated curate VBN cord-354833-vvlsqy36 140 22 and and CC cord-354833-vvlsqy36 140 23 analysed analyse VBD cord-354833-vvlsqy36 140 24 all all PDT cord-354833-vvlsqy36 140 25 the the DT cord-354833-vvlsqy36 140 26 published publish VBN cord-354833-vvlsqy36 140 27 data datum NNS cord-354833-vvlsqy36 140 28 on on IN cord-354833-vvlsqy36 140 29 influenza influenza NN cord-354833-vvlsqy36 140 30 A a DT cord-354833-vvlsqy36 140 31 virus virus NN cord-354833-vvlsqy36 140 32 antibody antibody NN cord-354833-vvlsqy36 140 33 and and CC cord-354833-vvlsqy36 140 34 T t NN cord-354833-vvlsqy36 140 35 - - HYPH cord-354833-vvlsqy36 140 36 cell cell NN cord-354833-vvlsqy36 140 37 epitopes epitope NNS cord-354833-vvlsqy36 140 38 33 33 CD cord-354833-vvlsqy36 140 39 . . . cord-354833-vvlsqy36 141 1 This this DT cord-354833-vvlsqy36 141 2 effort effort NN cord-354833-vvlsqy36 141 3 has have VBZ cord-354833-vvlsqy36 141 4 resulted result VBN cord-354833-vvlsqy36 141 5 in in IN cord-354833-vvlsqy36 141 6 an an DT cord-354833-vvlsqy36 141 7 inventory inventory NN cord-354833-vvlsqy36 141 8 of of IN cord-354833-vvlsqy36 141 9 the the DT cord-354833-vvlsqy36 141 10 existing exist VBG cord-354833-vvlsqy36 141 11 knowledge knowledge NN cord-354833-vvlsqy36 141 12 related relate VBN cord-354833-vvlsqy36 141 13 to to IN cord-354833-vvlsqy36 141 14 this this DT cord-354833-vvlsqy36 141 15 field field NN cord-354833-vvlsqy36 141 16 , , , cord-354833-vvlsqy36 141 17 and and CC cord-354833-vvlsqy36 141 18 will will MD cord-354833-vvlsqy36 141 19 also also RB cord-354833-vvlsqy36 141 20 allow allow VB cord-354833-vvlsqy36 141 21 us -PRON- PRP cord-354833-vvlsqy36 141 22 to to TO cord-354833-vvlsqy36 141 23 start start VB cord-354833-vvlsqy36 141 24 probing probe VBG cord-354833-vvlsqy36 141 25 possible possible JJ cord-354833-vvlsqy36 141 26 crossreactivities crossreactivitie NNS cord-354833-vvlsqy36 141 27 among among IN cord-354833-vvlsqy36 141 28 H5N1 H5N1 NNP cord-354833-vvlsqy36 141 29 avian avian JJ cord-354833-vvlsqy36 141 30 and and CC cord-354833-vvlsqy36 141 31 human human JJ cord-354833-vvlsqy36 141 32 influenza influenza NN cord-354833-vvlsqy36 141 33 virus virus NN cord-354833-vvlsqy36 141 34 strains strain NNS cord-354833-vvlsqy36 141 35 . . . cord-354833-vvlsqy36 142 1 The the DT cord-354833-vvlsqy36 142 2 analysis analysis NN cord-354833-vvlsqy36 142 3 revealed reveal VBD cord-354833-vvlsqy36 142 4 over over IN cord-354833-vvlsqy36 142 5 600 600 CD cord-354833-vvlsqy36 142 6 different different JJ cord-354833-vvlsqy36 142 7 influenza influenza NN cord-354833-vvlsqy36 142 8 virus virus NN cord-354833-vvlsqy36 142 9 epitopes epitope NNS cord-354833-vvlsqy36 142 10 , , , cord-354833-vvlsqy36 142 11 derived derive VBN cord-354833-vvlsqy36 142 12 from from IN cord-354833-vvlsqy36 142 13 58 58 CD cord-354833-vvlsqy36 142 14 different different JJ cord-354833-vvlsqy36 142 15 strains strain NNS cord-354833-vvlsqy36 142 16 and and CC cord-354833-vvlsqy36 142 17 10 10 CD cord-354833-vvlsqy36 142 18 viral viral JJ cord-354833-vvlsqy36 142 19 proteins protein NNS cord-354833-vvlsqy36 142 20 . . . cord-354833-vvlsqy36 143 1 As as IN cord-354833-vvlsqy36 143 2 all all PDT cord-354833-vvlsqy36 143 3 the the DT cord-354833-vvlsqy36 143 4 data datum NNS cord-354833-vvlsqy36 143 5 are be VBP cord-354833-vvlsqy36 143 6 freely freely RB cord-354833-vvlsqy36 143 7 available available JJ cord-354833-vvlsqy36 143 8 online online RB cord-354833-vvlsqy36 143 9 , , , cord-354833-vvlsqy36 143 10 this this DT cord-354833-vvlsqy36 143 11 effort effort NN cord-354833-vvlsqy36 143 12 translates translate VBZ cord-354833-vvlsqy36 143 13 into into IN cord-354833-vvlsqy36 143 14 a a DT cord-354833-vvlsqy36 143 15 single single JJ cord-354833-vvlsqy36 143 16 resource resource NN cord-354833-vvlsqy36 143 17 for for IN cord-354833-vvlsqy36 143 18 researchers researcher NNS cord-354833-vvlsqy36 143 19 that that WDT cord-354833-vvlsqy36 143 20 allows allow VBZ cord-354833-vvlsqy36 143 21 access access NN cord-354833-vvlsqy36 143 22 to to IN cord-354833-vvlsqy36 143 23 most most JJS cord-354833-vvlsqy36 143 24 existing existing JJ cord-354833-vvlsqy36 143 25 epitope epitope NN cord-354833-vvlsqy36 143 26 data datum NNS cord-354833-vvlsqy36 143 27 for for IN cord-354833-vvlsqy36 143 28 influenza influenza NN cord-354833-vvlsqy36 143 29 virus virus NN cord-354833-vvlsqy36 143 30 . . . cord-354833-vvlsqy36 144 1 For for IN cord-354833-vvlsqy36 144 2 example example NN cord-354833-vvlsqy36 144 3 , , , cord-354833-vvlsqy36 144 4 because because IN cord-354833-vvlsqy36 144 5 of of IN cord-354833-vvlsqy36 144 6 the the DT cord-354833-vvlsqy36 144 7 capacity capacity NN cord-354833-vvlsqy36 144 8 to to TO cord-354833-vvlsqy36 144 9 extract extract VB cord-354833-vvlsqy36 144 10 data datum NNS cord-354833-vvlsqy36 144 11 related relate VBN cord-354833-vvlsqy36 144 12 to to IN cord-354833-vvlsqy36 144 13 specific specific JJ cord-354833-vvlsqy36 144 14 contexts context NNS cord-354833-vvlsqy36 144 15 , , , cord-354833-vvlsqy36 144 16 an an DT cord-354833-vvlsqy36 144 17 interested interested JJ cord-354833-vvlsqy36 144 18 scientist scientist NN cord-354833-vvlsqy36 144 19 can can MD cord-354833-vvlsqy36 144 20 selectively selectively RB cord-354833-vvlsqy36 144 21 view view VB cord-354833-vvlsqy36 144 22 epitopes epitope NNS cord-354833-vvlsqy36 144 23 that that WDT cord-354833-vvlsqy36 144 24 are be VBP cord-354833-vvlsqy36 144 25 known know VBN cord-354833-vvlsqy36 144 26 to to TO cord-354833-vvlsqy36 144 27 be be VB cord-354833-vvlsqy36 144 28 associated associate VBN cord-354833-vvlsqy36 144 29 with with IN cord-354833-vvlsqy36 144 30 protection protection NN cord-354833-vvlsqy36 144 31 from from IN cord-354833-vvlsqy36 144 32 challenge challenge NN cord-354833-vvlsqy36 144 33 with with IN cord-354833-vvlsqy36 144 34 influenza influenza NN cord-354833-vvlsqy36 144 35 virus virus NN cord-354833-vvlsqy36 144 36 . . . cord-354833-vvlsqy36 145 1 By by IN cord-354833-vvlsqy36 145 2 the the DT cord-354833-vvlsqy36 145 3 use use NN cord-354833-vvlsqy36 145 4 of of IN cord-354833-vvlsqy36 145 5 to to TO cord-354833-vvlsqy36 145 6 populate populate VB cord-354833-vvlsqy36 145 7 the the DT cord-354833-vvlsqy36 145 8 database database NN cord-354833-vvlsqy36 145 9 with with IN cord-354833-vvlsqy36 145 10 epitope epitope NN cord-354833-vvlsqy36 145 11 information information NN cord-354833-vvlsqy36 145 12 is be VBZ cord-354833-vvlsqy36 145 13 completed complete VBN cord-354833-vvlsqy36 145 14 . . . cord-354833-vvlsqy36 146 1 The the DT cord-354833-vvlsqy36 146 2 focus focus NN cord-354833-vvlsqy36 146 3 now now RB cord-354833-vvlsqy36 146 4 is be VBZ cord-354833-vvlsqy36 146 5 on on IN cord-354833-vvlsqy36 146 6 enhancing enhance VBG cord-354833-vvlsqy36 146 7 the the DT cord-354833-vvlsqy36 146 8 value value NN cord-354833-vvlsqy36 146 9 of of IN cord-354833-vvlsqy36 146 10 this this DT cord-354833-vvlsqy36 146 11 information information NN cord-354833-vvlsqy36 146 12 to to IN cord-354833-vvlsqy36 146 13 the the DT cord-354833-vvlsqy36 146 14 user user NN cord-354833-vvlsqy36 146 15 community community NN cord-354833-vvlsqy36 146 16 . . . cord-354833-vvlsqy36 147 1 An an DT cord-354833-vvlsqy36 147 2 important important JJ cord-354833-vvlsqy36 147 3 component component NN cord-354833-vvlsqy36 147 4 of of IN cord-354833-vvlsqy36 147 5 the the DT cord-354833-vvlsqy36 147 6 rationale rationale NN cord-354833-vvlsqy36 147 7 for for IN cord-354833-vvlsqy36 147 8 writing write VBG cord-354833-vvlsqy36 147 9 this this DT cord-354833-vvlsqy36 147 10 article article NN cord-354833-vvlsqy36 147 11 is be VBZ cord-354833-vvlsqy36 147 12 to to TO cord-354833-vvlsqy36 147 13 involve involve VB cord-354833-vvlsqy36 147 14 the the DT cord-354833-vvlsqy36 147 15 scientific scientific JJ cord-354833-vvlsqy36 147 16 community community NN cord-354833-vvlsqy36 147 17 at at IN cord-354833-vvlsqy36 147 18 large large JJ cord-354833-vvlsqy36 147 19 in in IN cord-354833-vvlsqy36 147 20 the the DT cord-354833-vvlsqy36 147 21 realisation realisation NN cord-354833-vvlsqy36 147 22 of of IN cord-354833-vvlsqy36 147 23 the the DT cord-354833-vvlsqy36 147 24 best good JJS cord-354833-vvlsqy36 147 25 possible possible JJ cord-354833-vvlsqy36 147 26 epitope epitope NN cord-354833-vvlsqy36 147 27 database database NN cord-354833-vvlsqy36 147 28 by by IN cord-354833-vvlsqy36 147 29 stimulating stimulate VBG cord-354833-vvlsqy36 147 30 debate debate NN cord-354833-vvlsqy36 147 31 and and CC cord-354833-vvlsqy36 147 32 feedback feedback NN cord-354833-vvlsqy36 147 33 on on IN cord-354833-vvlsqy36 147 34 these these DT cord-354833-vvlsqy36 147 35 issues issue NNS cord-354833-vvlsqy36 147 36 , , , cord-354833-vvlsqy36 147 37 as as IN cord-354833-vvlsqy36 147 38 changes change NNS cord-354833-vvlsqy36 147 39 and and CC cord-354833-vvlsqy36 147 40 improvements improvement NNS cord-354833-vvlsqy36 147 41 are be VBP cord-354833-vvlsqy36 147 42 continuously continuously RB cord-354833-vvlsqy36 147 43 considered consider VBN cord-354833-vvlsqy36 147 44 and and CC cord-354833-vvlsqy36 147 45 contemplated contemplate VBN cord-354833-vvlsqy36 147 46 . . . cord-354833-vvlsqy36 148 1 The the DT cord-354833-vvlsqy36 148 2 design design NN cord-354833-vvlsqy36 148 3 and and CC cord-354833-vvlsqy36 148 4 implementation implementation NN cord-354833-vvlsqy36 148 5 of of IN cord-354833-vvlsqy36 148 6 the the DT cord-354833-vvlsqy36 148 7 immune immune JJ cord-354833-vvlsqy36 148 8 epitope epitope NN cord-354833-vvlsqy36 148 9 database database NN cord-354833-vvlsqy36 148 10 and and CC cord-354833-vvlsqy36 148 11 analysis analysis NN cord-354833-vvlsqy36 148 12 resource resource NN cord-354833-vvlsqy36 148 13 Immunoinformatics Immunoinformatics NNP cord-354833-vvlsqy36 148 14 comes come VBZ cord-354833-vvlsqy36 148 15 of of IN cord-354833-vvlsqy36 148 16 age age NN cord-354833-vvlsqy36 148 17 From from IN cord-354833-vvlsqy36 148 18 functional functional JJ cord-354833-vvlsqy36 148 19 genomics genomic NNS cord-354833-vvlsqy36 148 20 to to IN cord-354833-vvlsqy36 148 21 functional functional JJ cord-354833-vvlsqy36 148 22 immunomics immunomic NNS cord-354833-vvlsqy36 148 23 : : : cord-354833-vvlsqy36 148 24 new new JJ cord-354833-vvlsqy36 148 25 challenges challenge NNS cord-354833-vvlsqy36 148 26 , , , cord-354833-vvlsqy36 148 27 old old JJ cord-354833-vvlsqy36 148 28 problems problem NNS cord-354833-vvlsqy36 148 29 , , , cord-354833-vvlsqy36 148 30 big big JJ cord-354833-vvlsqy36 148 31 rewards reward NNS cord-354833-vvlsqy36 148 32 Curation Curation NNP cord-354833-vvlsqy36 148 33 of of IN cord-354833-vvlsqy36 148 34 complex complex JJ cord-354833-vvlsqy36 148 35 , , , cord-354833-vvlsqy36 148 36 context context NN cord-354833-vvlsqy36 148 37 - - HYPH cord-354833-vvlsqy36 148 38 dependent dependent JJ cord-354833-vvlsqy36 148 39 immunological immunological JJ cord-354833-vvlsqy36 148 40 data datum NNS cord-354833-vvlsqy36 148 41 National National NNP cord-354833-vvlsqy36 148 42 Center Center NNP cord-354833-vvlsqy36 148 43 for for IN cord-354833-vvlsqy36 148 44 Biomedical Biomedical NNP cord-354833-vvlsqy36 148 45 Ontology Ontology NNP cord-354833-vvlsqy36 148 46 : : : cord-354833-vvlsqy36 148 47 advancing advance VBG cord-354833-vvlsqy36 148 48 biomedicine biomedicine NN cord-354833-vvlsqy36 148 49 through through IN cord-354833-vvlsqy36 148 50 structured structured JJ cord-354833-vvlsqy36 148 51 organization organization NN cord-354833-vvlsqy36 148 52 of of IN cord-354833-vvlsqy36 148 53 scientific scientific JJ cord-354833-vvlsqy36 148 54 knowledge knowledge NN cord-354833-vvlsqy36 148 55 IMGT imgt NN cord-354833-vvlsqy36 148 56 - - HYPH cord-354833-vvlsqy36 148 57 ONTOLOGY ontology NN cord-354833-vvlsqy36 148 58 for for IN cord-354833-vvlsqy36 148 59 immunogenetics immunogenetic NNS cord-354833-vvlsqy36 148 60 and and CC cord-354833-vvlsqy36 148 61 immunoinformatics immunoinformatic NNS cord-354833-vvlsqy36 149 1 An an DT cord-354833-vvlsqy36 149 2 ontology ontology NN cord-354833-vvlsqy36 149 3 for for IN cord-354833-vvlsqy36 149 4 immune immune JJ cord-354833-vvlsqy36 149 5 epitopes epitope NNS cord-354833-vvlsqy36 149 6 : : : cord-354833-vvlsqy36 149 7 application application NN cord-354833-vvlsqy36 149 8 to to IN cord-354833-vvlsqy36 149 9 the the DT cord-354833-vvlsqy36 149 10 design design NN cord-354833-vvlsqy36 149 11 of of IN cord-354833-vvlsqy36 149 12 a a DT cord-354833-vvlsqy36 149 13 broad broad JJ cord-354833-vvlsqy36 149 14 scope scope NN cord-354833-vvlsqy36 149 15 database database NN cord-354833-vvlsqy36 149 16 of of IN cord-354833-vvlsqy36 149 17 immune immune JJ cord-354833-vvlsqy36 149 18 reactivities reactivity NNS cord-354833-vvlsqy36 149 19 Development Development NNP cord-354833-vvlsqy36 149 20 of of IN cord-354833-vvlsqy36 149 21 FuGO FuGO NNP cord-354833-vvlsqy36 149 22 : : : cord-354833-vvlsqy36 149 23 an an DT cord-354833-vvlsqy36 149 24 ontology ontology NN cord-354833-vvlsqy36 149 25 for for IN cord-354833-vvlsqy36 149 26 functional functional JJ cord-354833-vvlsqy36 149 27 genomics genomic NNS cord-354833-vvlsqy36 149 28 investigations investigation NNS cord-354833-vvlsqy36 150 1 The the DT cord-354833-vvlsqy36 150 2 Gene Gene NNP cord-354833-vvlsqy36 150 3 Ontology Ontology NNP cord-354833-vvlsqy36 150 4 ( ( -LRB- cord-354833-vvlsqy36 150 5 GO GO NNP cord-354833-vvlsqy36 150 6 ) ) -RRB- cord-354833-vvlsqy36 150 7 database database NN cord-354833-vvlsqy36 150 8 and and CC cord-354833-vvlsqy36 150 9 informatics informatics NN cord-354833-vvlsqy36 150 10 resource resource NN cord-354833-vvlsqy36 150 11 Ontology Ontology NNP cord-354833-vvlsqy36 150 12 development development NN cord-354833-vvlsqy36 150 13 for for IN cord-354833-vvlsqy36 150 14 biological biological JJ cord-354833-vvlsqy36 150 15 systems system NNS cord-354833-vvlsqy36 151 1 A a DT cord-354833-vvlsqy36 151 2 survey survey NN cord-354833-vvlsqy36 151 3 of of IN cord-354833-vvlsqy36 151 4 current current JJ cord-354833-vvlsqy36 151 5 work work NN cord-354833-vvlsqy36 151 6 in in IN cord-354833-vvlsqy36 151 7 biomedical biomedical JJ cord-354833-vvlsqy36 151 8 text text NN cord-354833-vvlsqy36 151 9 mining mining NN cord-354833-vvlsqy36 151 10 Literature literature NN cord-354833-vvlsqy36 151 11 mining mining NN cord-354833-vvlsqy36 151 12 for for IN cord-354833-vvlsqy36 151 13 the the DT cord-354833-vvlsqy36 151 14 biologist biologist NN cord-354833-vvlsqy36 151 15 : : : cord-354833-vvlsqy36 151 16 from from IN cord-354833-vvlsqy36 151 17 information information NN cord-354833-vvlsqy36 151 18 retrieval retrieval NN cord-354833-vvlsqy36 151 19 to to IN cord-354833-vvlsqy36 151 20 biological biological JJ cord-354833-vvlsqy36 151 21 discovery discovery NN cord-354833-vvlsqy36 151 22 Supporting support VBG cord-354833-vvlsqy36 151 23 the the DT cord-354833-vvlsqy36 151 24 curation curation NN cord-354833-vvlsqy36 151 25 of of IN cord-354833-vvlsqy36 151 26 biological biological JJ cord-354833-vvlsqy36 151 27 databases database NNS cord-354833-vvlsqy36 151 28 with with IN cord-354833-vvlsqy36 151 29 reusable reusable JJ cord-354833-vvlsqy36 151 30 text text NN cord-354833-vvlsqy36 151 31 mining mining NN cord-354833-vvlsqy36 151 32 PreBIND prebind NN cord-354833-vvlsqy36 151 33 and and CC cord-354833-vvlsqy36 151 34 Textomy Textomy NNP cord-354833-vvlsqy36 151 35 - - HYPH cord-354833-vvlsqy36 151 36 mining mine VBG cord-354833-vvlsqy36 151 37 the the DT cord-354833-vvlsqy36 151 38 biomedical biomedical JJ cord-354833-vvlsqy36 151 39 literature literature NN cord-354833-vvlsqy36 151 40 for for IN cord-354833-vvlsqy36 151 41 protein protein NN cord-354833-vvlsqy36 151 42 - - HYPH cord-354833-vvlsqy36 151 43 protein protein NN cord-354833-vvlsqy36 151 44 interactions interaction NNS cord-354833-vvlsqy36 151 45 using use VBG cord-354833-vvlsqy36 151 46 a a DT cord-354833-vvlsqy36 151 47 support support NN cord-354833-vvlsqy36 151 48 vector vector NN cord-354833-vvlsqy36 151 49 machine machine NN cord-354833-vvlsqy36 151 50 Evaluation Evaluation NNP cord-354833-vvlsqy36 151 51 of of IN cord-354833-vvlsqy36 151 52 text text NN cord-354833-vvlsqy36 151 53 data datum NNS cord-354833-vvlsqy36 151 54 mining mining NN cord-354833-vvlsqy36 151 55 for for IN cord-354833-vvlsqy36 151 56 database database NN cord-354833-vvlsqy36 151 57 curation curation NN cord-354833-vvlsqy36 151 58 : : : cord-354833-vvlsqy36 151 59 lessons lesson NNS cord-354833-vvlsqy36 151 60 learned learn VBN cord-354833-vvlsqy36 151 61 from from IN cord-354833-vvlsqy36 151 62 the the DT cord-354833-vvlsqy36 151 63 KDD KDD NNP cord-354833-vvlsqy36 151 64 Challenge Challenge NNP cord-354833-vvlsqy36 151 65 Cup Cup NNP cord-354833-vvlsqy36 151 66 Immunomics Immunomics NNPS cord-354833-vvlsqy36 151 67 : : : cord-354833-vvlsqy36 151 68 discovering discover VBG cord-354833-vvlsqy36 151 69 new new JJ cord-354833-vvlsqy36 151 70 targets target NNS cord-354833-vvlsqy36 151 71 for for IN cord-354833-vvlsqy36 151 72 vaccines vaccine NNS cord-354833-vvlsqy36 151 73 and and CC cord-354833-vvlsqy36 151 74 therapeutics therapeutic NNS cord-354833-vvlsqy36 151 75 SYFPEITHI SYFPEITHI NNP cord-354833-vvlsqy36 151 76 : : : cord-354833-vvlsqy36 151 77 database database NN cord-354833-vvlsqy36 151 78 for for IN cord-354833-vvlsqy36 151 79 MHC MHC NNP cord-354833-vvlsqy36 151 80 ligands ligand NNS cord-354833-vvlsqy36 151 81 and and CC cord-354833-vvlsqy36 151 82 peptide peptide NN cord-354833-vvlsqy36 151 83 motifs motif NNS cord-354833-vvlsqy36 151 84 IMGT IMGT NNP cord-354833-vvlsqy36 151 85 / / SYM cord-354833-vvlsqy36 151 86 LIGM LIGM NNP cord-354833-vvlsqy36 151 87 - - HYPH cord-354833-vvlsqy36 151 88 DB DB NNP cord-354833-vvlsqy36 151 89 , , , cord-354833-vvlsqy36 151 90 the the DT cord-354833-vvlsqy36 151 91 IMGT IMGT NNP cord-354833-vvlsqy36 151 92 comprehensive comprehensive JJ cord-354833-vvlsqy36 151 93 database database NN cord-354833-vvlsqy36 151 94 of of IN cord-354833-vvlsqy36 151 95 immunoglobulin immunoglobulin NN cord-354833-vvlsqy36 151 96 and and CC cord-354833-vvlsqy36 151 97 T t NN cord-354833-vvlsqy36 151 98 cell cell NN cord-354833-vvlsqy36 151 99 receptor receptor NN cord-354833-vvlsqy36 151 100 nucleotide nucleotide NN cord-354833-vvlsqy36 151 101 sequences sequence NNS cord-354833-vvlsqy36 152 1 AntiJen AntiJen NNP cord-354833-vvlsqy36 152 2 : : : cord-354833-vvlsqy36 152 3 a a DT cord-354833-vvlsqy36 152 4 quantitative quantitative JJ cord-354833-vvlsqy36 152 5 immunology immunology NN cord-354833-vvlsqy36 152 6 database database NN cord-354833-vvlsqy36 152 7 integrating integrate VBG cord-354833-vvlsqy36 153 1 functional functional JJ cord-354833-vvlsqy36 153 2 , , , cord-354833-vvlsqy36 153 3 thermodynamic thermodynamic JJ cord-354833-vvlsqy36 153 4 , , , cord-354833-vvlsqy36 153 5 kinetic kinetic JJ cord-354833-vvlsqy36 153 6 , , , cord-354833-vvlsqy36 153 7 biophysical biophysical JJ cord-354833-vvlsqy36 153 8 , , , cord-354833-vvlsqy36 153 9 and and CC cord-354833-vvlsqy36 153 10 cellular cellular JJ cord-354833-vvlsqy36 153 11 data datum NNS cord-354833-vvlsqy36 153 12 An an DT cord-354833-vvlsqy36 153 13 update update NN cord-354833-vvlsqy36 153 14 on on IN cord-354833-vvlsqy36 153 15 the the DT cord-354833-vvlsqy36 153 16 functional functional JJ cord-354833-vvlsqy36 153 17 molecular molecular JJ cord-354833-vvlsqy36 153 18 immunology immunology NN cord-354833-vvlsqy36 153 19 ( ( -LRB- cord-354833-vvlsqy36 153 20 FIMM FIMM NNP cord-354833-vvlsqy36 153 21 ) ) -RRB- cord-354833-vvlsqy36 153 22 database database NN cord-354833-vvlsqy36 153 23 MHCBN MHCBN NNP cord-354833-vvlsqy36 153 24 : : : cord-354833-vvlsqy36 153 25 a a DT cord-354833-vvlsqy36 153 26 comprehensive comprehensive JJ cord-354833-vvlsqy36 153 27 database database NN cord-354833-vvlsqy36 153 28 of of IN cord-354833-vvlsqy36 153 29 MHC MHC NNP cord-354833-vvlsqy36 153 30 binding bind VBG cord-354833-vvlsqy36 153 31 and and CC cord-354833-vvlsqy36 153 32 non non JJ cord-354833-vvlsqy36 153 33 - - JJ cord-354833-vvlsqy36 153 34 binding binding JJ cord-354833-vvlsqy36 153 35 peptides peptide NNS cord-354833-vvlsqy36 153 36 Population Population NNP cord-354833-vvlsqy36 153 37 of of IN cord-354833-vvlsqy36 153 38 the the DT cord-354833-vvlsqy36 153 39 HLA HLA NNP cord-354833-vvlsqy36 153 40 ligand ligand NN cord-354833-vvlsqy36 153 41 database database NN cord-354833-vvlsqy36 153 42 HIV HIV NNP cord-354833-vvlsqy36 153 43 Molecular Molecular NNP cord-354833-vvlsqy36 153 44 Immunology Immunology NNP cord-354833-vvlsqy36 153 45 Los Los NNP cord-354833-vvlsqy36 153 46 Alamos Alamos NNP cord-354833-vvlsqy36 153 47 hepatitis hepatitis NN cord-354833-vvlsqy36 153 48 C C NNP cord-354833-vvlsqy36 153 49 immunology immunology NN cord-354833-vvlsqy36 153 50 database database NN cord-354833-vvlsqy36 154 1 The the DT cord-354833-vvlsqy36 154 2 immune immune JJ cord-354833-vvlsqy36 154 3 epitope epitope NN cord-354833-vvlsqy36 154 4 database database NN cord-354833-vvlsqy36 154 5 and and CC cord-354833-vvlsqy36 154 6 analysis analysis NN cord-354833-vvlsqy36 154 7 resource resource NN cord-354833-vvlsqy36 154 8 : : : cord-354833-vvlsqy36 154 9 from from IN cord-354833-vvlsqy36 154 10 vision vision NN cord-354833-vvlsqy36 154 11 to to IN cord-354833-vvlsqy36 154 12 blueprint blueprint NN cord-354833-vvlsqy36 154 13 A a DT cord-354833-vvlsqy36 154 14 community community NN cord-354833-vvlsqy36 154 15 resource resource NN cord-354833-vvlsqy36 154 16 benchmarking benchmarking NN cord-354833-vvlsqy36 154 17 predictions prediction NNS cord-354833-vvlsqy36 154 18 of of IN cord-354833-vvlsqy36 154 19 peptide peptide NN cord-354833-vvlsqy36 154 20 binding bind VBG cord-354833-vvlsqy36 154 21 to to IN cord-354833-vvlsqy36 154 22 MHC MHC NNP cord-354833-vvlsqy36 155 1 -I -i WDT cord-354833-vvlsqy36 155 2 molecules molecule VBZ cord-354833-vvlsqy36 155 3 A a DT cord-354833-vvlsqy36 155 4 decade decade NN cord-354833-vvlsqy36 155 5 of of IN cord-354833-vvlsqy36 155 6 CASP CASP NNP cord-354833-vvlsqy36 155 7 : : : cord-354833-vvlsqy36 155 8 progress progress NN cord-354833-vvlsqy36 155 9 , , , cord-354833-vvlsqy36 155 10 bottlenecks bottleneck NNS cord-354833-vvlsqy36 155 11 and and CC cord-354833-vvlsqy36 155 12 prognosis prognosis NN cord-354833-vvlsqy36 155 13 in in IN cord-354833-vvlsqy36 155 14 protein protein NN cord-354833-vvlsqy36 155 15 structure structure NN cord-354833-vvlsqy36 155 16 prediction prediction NN cord-354833-vvlsqy36 155 17 Benchmarking Benchmarking NNP cord-354833-vvlsqy36 155 18 B B NNP cord-354833-vvlsqy36 155 19 cell cell NN cord-354833-vvlsqy36 155 20 epitope epitope NN cord-354833-vvlsqy36 155 21 prediction prediction NN cord-354833-vvlsqy36 155 22 : : : cord-354833-vvlsqy36 155 23 underperformance underperformance NN cord-354833-vvlsqy36 155 24 of of IN cord-354833-vvlsqy36 155 25 existing exist VBG cord-354833-vvlsqy36 155 26 methods method NNS cord-354833-vvlsqy36 155 27 Towards towards IN cord-354833-vvlsqy36 155 28 a a DT cord-354833-vvlsqy36 155 29 consensus consensus NN cord-354833-vvlsqy36 155 30 on on IN cord-354833-vvlsqy36 155 31 datasets dataset NNS cord-354833-vvlsqy36 155 32 and and CC cord-354833-vvlsqy36 155 33 evaluation evaluation NN cord-354833-vvlsqy36 155 34 metrics metric NNS cord-354833-vvlsqy36 155 35 for for IN cord-354833-vvlsqy36 155 36 developing develop VBG cord-354833-vvlsqy36 155 37 B b NN cord-354833-vvlsqy36 155 38 - - HYPH cord-354833-vvlsqy36 155 39 cell cell NN cord-354833-vvlsqy36 155 40 epitope epitope NN cord-354833-vvlsqy36 155 41 prediction prediction NN cord-354833-vvlsqy36 155 42 tools tool NNS cord-354833-vvlsqy36 155 43 Predicting predict VBG cord-354833-vvlsqy36 155 44 population population NN cord-354833-vvlsqy36 155 45 coverage coverage NN cord-354833-vvlsqy36 155 46 of of IN cord-354833-vvlsqy36 155 47 T t NN cord-354833-vvlsqy36 155 48 - - HYPH cord-354833-vvlsqy36 155 49 cell cell NN cord-354833-vvlsqy36 155 50 epitope epitope NN cord-354833-vvlsqy36 155 51 - - HYPH cord-354833-vvlsqy36 155 52 based base VBN cord-354833-vvlsqy36 155 53 diagnostics diagnostic NNS cord-354833-vvlsqy36 155 54 and and CC cord-354833-vvlsqy36 155 55 vaccines vaccine NNS cord-354833-vvlsqy36 155 56 EpitopeViewer EpitopeViewer NNP cord-354833-vvlsqy36 155 57 : : : cord-354833-vvlsqy36 155 58 a a DT cord-354833-vvlsqy36 155 59 Java Java NNP cord-354833-vvlsqy36 155 60 application application NN cord-354833-vvlsqy36 155 61 for for IN cord-354833-vvlsqy36 155 62 the the DT cord-354833-vvlsqy36 155 63 visualization visualization NN cord-354833-vvlsqy36 155 64 and and CC cord-354833-vvlsqy36 155 65 analysis analysis NN cord-354833-vvlsqy36 155 66 of of IN cord-354833-vvlsqy36 155 67 immune immune JJ cord-354833-vvlsqy36 155 68 epitopes epitope NNS cord-354833-vvlsqy36 155 69 in in IN cord-354833-vvlsqy36 155 70 the the DT cord-354833-vvlsqy36 155 71 Immune Immune NNP cord-354833-vvlsqy36 155 72 Epitope Epitope NNP cord-354833-vvlsqy36 155 73 Database Database NNP cord-354833-vvlsqy36 155 74 and and CC cord-354833-vvlsqy36 155 75 Analysis Analysis NNP cord-354833-vvlsqy36 155 76 Resource Resource NNP cord-354833-vvlsqy36 155 77 ( ( -LRB- cord-354833-vvlsqy36 155 78 IEDB IEDB NNP cord-354833-vvlsqy36 155 79 ) ) -RRB- cord-354833-vvlsqy36 156 1 Ab Ab NNP cord-354833-vvlsqy36 156 2 and and CC cord-354833-vvlsqy36 156 3 T T NNP cord-354833-vvlsqy36 156 4 cell cell NN cord-354833-vvlsqy36 156 5 epitopes epitope NNS cord-354833-vvlsqy36 156 6 of of IN cord-354833-vvlsqy36 156 7 influenza influenza NN cord-354833-vvlsqy36 156 8 A a DT cord-354833-vvlsqy36 156 9 virus virus NN cord-354833-vvlsqy36 156 10 , , , cord-354833-vvlsqy36 156 11 knowledge knowledge NN cord-354833-vvlsqy36 156 12 and and CC cord-354833-vvlsqy36 156 13 opportunities opportunity NNS cord-354833-vvlsqy36 156 14 Mapping mapping NN cord-354833-vvlsqy36 156 15 of of IN cord-354833-vvlsqy36 156 16 antigenic antigenic JJ cord-354833-vvlsqy36 156 17 sites site NNS cord-354833-vvlsqy36 156 18 on on IN cord-354833-vvlsqy36 156 19 the the DT cord-354833-vvlsqy36 156 20 nucleocapsid nucleocapsid NNP cord-354833-vvlsqy36 156 21 protein protein NN cord-354833-vvlsqy36 156 22 of of IN cord-354833-vvlsqy36 156 23 the the DT cord-354833-vvlsqy36 156 24 severe severe JJ cord-354833-vvlsqy36 156 25 acute acute JJ cord-354833-vvlsqy36 156 26 respiratory respiratory JJ cord-354833-vvlsqy36 156 27 syndrome syndrome NN cord-354833-vvlsqy36 156 28 coronavirus coronavirus NN cord-354833-vvlsqy36 157 1 I -PRON- PRP cord-354833-vvlsqy36 157 2 thank thank VBP cord-354833-vvlsqy36 157 3 J. J. NNP cord-354833-vvlsqy36 157 4 Kang Kang NNP cord-354833-vvlsqy36 157 5 , , , cord-354833-vvlsqy36 157 6 P. P. NNP cord-354833-vvlsqy36 157 7 Schwartzberg Schwartzberg NNP cord-354833-vvlsqy36 157 8 , , , cord-354833-vvlsqy36 157 9 M. M. NNP cord-354833-vvlsqy36 157 10 Felices Felices NNPS cord-354833-vvlsqy36 157 11 , , , cord-354833-vvlsqy36 157 12 and and CC cord-354833-vvlsqy36 157 13 A. a. NN cord-354833-vvlsqy36 157 14 Prince Prince NNP cord-354833-vvlsqy36 157 15 for for IN cord-354833-vvlsqy36 157 16 helpful helpful JJ cord-354833-vvlsqy36 157 17 discussions discussion NNS cord-354833-vvlsqy36 157 18 . . . cord-354833-vvlsqy36 158 1 This this DT cord-354833-vvlsqy36 158 2 work work NN cord-354833-vvlsqy36 158 3 was be VBD cord-354833-vvlsqy36 158 4 supported support VBN cord-354833-vvlsqy36 158 5 by by IN cord-354833-vvlsqy36 158 6 grants grant NNS cord-354833-vvlsqy36 158 7 from from IN cord-354833-vvlsqy36 158 8 the the DT cord-354833-vvlsqy36 158 9 NIH NIH NNP cord-354833-vvlsqy36 158 10 ( ( -LRB- cord-354833-vvlsqy36 158 11 AI37584 ai37584 NN cord-354833-vvlsqy36 158 12 ) ) -RRB- cord-354833-vvlsqy36 158 13 and and CC cord-354833-vvlsqy36 158 14 the the DT cord-354833-vvlsqy36 158 15 Center Center NNP cord-354833-vvlsqy36 158 16 for for IN cord-354833-vvlsqy36 158 17 Disease Disease NNP cord-354833-vvlsqy36 158 18 Control Control NNP cord-354833-vvlsqy36 158 19 ( ( -LRB- cord-354833-vvlsqy36 158 20 CI000101 ci000101 NN cord-354833-vvlsqy36 158 21 ) ) -RRB- cord-354833-vvlsqy36 158 22 . . . cord-354833-vvlsqy36 159 1 We -PRON- PRP cord-354833-vvlsqy36 159 2 thank thank VBP cord-354833-vvlsqy36 159 3 J. J. NNP cord-354833-vvlsqy36 159 4 Ponomarenko Ponomarenko NNP cord-354833-vvlsqy36 159 5 and and CC cord-354833-vvlsqy36 159 6 P. P. NNP cord-354833-vvlsqy36 159 7 Bourne Bourne NNP cord-354833-vvlsqy36 159 8 at at IN cord-354833-vvlsqy36 159 9 the the DT cord-354833-vvlsqy36 159 10 San San NNP cord-354833-vvlsqy36 159 11 Diego Diego NNP cord-354833-vvlsqy36 159 12 Supercomputer Supercomputer NNP cord-354833-vvlsqy36 159 13 Center Center NNP cord-354833-vvlsqy36 159 14 , , , cord-354833-vvlsqy36 159 15 who who WP cord-354833-vvlsqy36 159 16 developed develop VBD cord-354833-vvlsqy36 159 17 the the DT cord-354833-vvlsqy36 159 18 Homology Homology NNP cord-354833-vvlsqy36 159 19 Mapping mapping NN cord-354833-vvlsqy36 159 20 tool tool NN cord-354833-vvlsqy36 159 21 . . . cord-354833-vvlsqy36 160 1 This this DT cord-354833-vvlsqy36 160 2 work work NN cord-354833-vvlsqy36 160 3 was be VBD cord-354833-vvlsqy36 160 4 supported support VBN cord-354833-vvlsqy36 160 5 by by IN cord-354833-vvlsqy36 160 6 the the DT cord-354833-vvlsqy36 160 7 National National NNP cord-354833-vvlsqy36 160 8 Institutes Institutes NNPS cord-354833-vvlsqy36 160 9 of of IN cord-354833-vvlsqy36 160 10 Health Health NNP cord-354833-vvlsqy36 160 11 , , , cord-354833-vvlsqy36 160 12 USA USA NNP cord-354833-vvlsqy36 160 13 . . . cord-354833-vvlsqy36 161 1 The the DT cord-354833-vvlsqy36 161 2 authors author NNS cord-354833-vvlsqy36 161 3 declare declare VBP cord-354833-vvlsqy36 161 4 no no DT cord-354833-vvlsqy36 161 5 competing compete VBG cord-354833-vvlsqy36 161 6 financial financial JJ cord-354833-vvlsqy36 161 7 interests interest NNS cord-354833-vvlsqy36 161 8 . . . cord-354833-vvlsqy36 162 1 The the DT cord-354833-vvlsqy36 162 2 authors author NNS cord-354833-vvlsqy36 162 3 declare declare VBP cord-354833-vvlsqy36 162 4 no no DT cord-354833-vvlsqy36 162 5 competing compete VBG cord-354833-vvlsqy36 162 6 financial financial JJ cord-354833-vvlsqy36 162 7 interests interest NNS cord-354833-vvlsqy36 162 8 . . .