id author title date pages extension mime words sentences flesch summary cache txt cord-327444-y2464gjh Wilson, M.R. Meningitis, Viral 2014-05-01 .txt text/plain 3377 191 40 The concept that agents other than bacteria can invade the central nervous system (CNS) began with the emergence of poliomyelitis as an epidemic infection and, subsequently, with the realization that similar meningeal inflammation and cerebrospinal fluid (CSF) pleocytosis occurred in as many as 60% of patients with mumps parotitis. That meningitis could be caused by other 'filterable agents' (i.e., viruses) was demonstrated by Rivers and Scot, who in 1935 recovered lymphocytic choriomeningitis virus (LCMV) from the CSF of an affected patient. Recent studies employing polymerase chain reaction (PCR) methods, however, confirm older observations that enteroviral CNS infections occur throughout the year, and many previously undiagnosed cases of viral meningitis occurring during winter months are also caused by these viruses. The most common domestic arthropodborne agents associated with viral meningitis include St. Louis encephalitis virus, the California/LaCrosse group of viruses, Colorado tick fever, and West Nile virus, which caused an explosive outbreak when it first arrived in the United States in 1999 and more recently in 2012. ./cache/cord-327444-y2464gjh.txt ./txt/cord-327444-y2464gjh.txt