id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-310299-isdsestc	Hosseini, Akram A.	Delirium as a presenting feature in COVID-19: neuroinvasive infection or autoimmune encephalopathy?	2020-06-09		.txt	text/plain	981	84	46	1 We report two cases of severe acute respiratory syndrome coronavirus-2 (SARS-CoV2) infection with acute onset of altered mental status and delirium with normal respiration and metabolic balance in the first 48 hours. Despite normal brain CT at 48 hours, MRI on day 6 showed three hyperintense foci on diffusion-weighted images, but no overt restriction, consistent with T2-shine-through suggesting cellular infiltration/inflammation or small infarcts ( Figure 1 ). 1,2 However, there is currently no report of limbic encephalitis associated with COVID-19 that presented with delirium in the absence of respiratory, metabolic or systemic features, while patients may be hidden sources of spreading the virus in busy clinical settings. The detection of SARS-CoV2 in the CSF in a patient with meningo-encephalitis supports neurotropic and neuroinvasive potential of the virus 2 presumably through the blood vesselrich meninges once the blood brain barrier is damaged. Central Nervous System Involvement by Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2)	./cache/cord-310299-isdsestc.txt	./txt/cord-310299-isdsestc.txt