id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-286149-awhnjwyc	Hoon‐Hanks, L.L.	Metagenomic Investigation of Idiopathic Meningoencephalomyelitis in Dogs	2017-12-02		.txt	text/plain	5441	289	51	In previous investigations of MUO in dogs, only brain samples were tested for infectious agents; however, CSF is a common sample utilized in the clinical evaluation of neurologic disease for the detection of infectious agent nucleic acids, especially by PCR. Additionally, RNA was extracted from postmortem brain samples from a mule deer (Odocoileus hemionus), green tree python (Morelia viridis), American crow (Corvus brachyrhynchos), and American robin (Turdus migratorius), all of which had previously been tested by PCR, metagenomic sequencing, or both, and were found to be infected with specific known infectious agents. There are several possible biological and technical explanations for our study's inability to identify a candidate etiologic agent for MUO, including the underlying pathogenesis of the disease, sample type and collection methods, case inclusion criteria, sensitivity of diagnostics, and database limitations.	./cache/cord-286149-awhnjwyc.txt	./txt/cord-286149-awhnjwyc.txt