id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-258787-n49zrfsp	Carnevale, Silvia	The complexity of neutrophils in health and disease: Focus on cancer	2020-09-18		.txt	text/plain	9165	474	35	Here we review the current understandings on neutrophils biology from their development to the mechanisms of their trafficking and functions in health and disease, with a focus on their role in tumour biology and their prognostic significance in human cancer. Abbreviations: 3-MCA, 3-methylcholathrene; ACKR2, atypical chemokine receptor 2; APC, antigen presenting cell; G-CSF, granulocytes colony stimulating factor; G-MDSCs, granulocytes-myeloid-derived suppressor cells; GM-CSF, granulocytes-macrophages colony stimulating factor; GMPs, granulocyte monocyte progenitors; iNOS, inducible nitric oxide synthase; M-MDSCs, monocytes-myeloid-derived suppressor cells; MMP-9, matrix metallopeptidase 9; MPO, myeloperoxidase; NETs, neutrophil extracellular traps; NK, natural killer; PRRs, pattern recognition receptors; ROS, eactive oxygen species; TANs, tumour-associated neutrophils; TCR, T cell receptor; TILs, tumour infiltrating leukocytes; TME, tumour microenvironment; TRAIL, TNF-related apoptosis inducing ligand; TRPM2, transient receptor potential cation channel subfamily M, member 2; UTC, unconventional T cell. Origin and role of a subset of tumor-associated neutrophils with antigen-presenting cell features in early-stage human lung Cancer	./cache/cord-258787-n49zrfsp.txt	./txt/cord-258787-n49zrfsp.txt