id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-102725-k0xhbssu	Norwood, Jordan N.	Intranasal Administration of Functionalized Soot Particles Disrupts Olfactory Sensory Neuron Progenitor Cells in the Neuroepithelium	2020-08-19		.txt	text/plain	4736	273	51	Here, we investigated the impact of intranasal treatment of combustion products (laboratory-generated soots) and their oxygen functionalized derivatives on mouse olfactory sensory neurons, olfactory nerve cell progenitors, and the behavior of the mouse. To better understand the effects of air pollution on olfactory sensory neurons and their progenitor cells, we investigated the impact of intranasal treatment with surrogates for combustion generated 'soots' synthesized from carbon black precursors. However, oxygen-functionalized soots greatly decreased the levels of olfactory progenitor cells, suggesting that exposure to these particles can set up a long-term decrease in the number of OSNs. Such a decrease could lead to anosmia and decreased CSF movement. In order to understand how air pollution might affect olfactory sensory neurons and their progenitor cells, we treated mice intranasally with surrogate soot-like particles that either had oxygen-4 functionalized surfaces or non-functionalized surfaces.	./cache/cord-102725-k0xhbssu.txt	./txt/cord-102725-k0xhbssu.txt