id author title date pages extension mime words sentences flesch summary cache txt cord-001583-le1mc045 Liu, Yong-Juan The combination of decoy receptor 3 and soluble triggering receptor expressed on myeloid cells-1 for the diagnosis of nosocomial bacterial meningitis 2015-03-23 .txt text/plain 3191 202 49 CONCLUSIONS: Combined measurement of CSF DcR3 and sTREM-1 concentrations improved the prediction of nosocomial bacterial meningitis. Our previous study has proved that levels of DcR3 are significantly elevated in patients with bacterial meningitis and it may act as a useful biomarker of bacterial meningitis [13] . In this study, we combined the markers of DcR3 and sTREM-1 into a simple score, named as "bioscore", which was proved to be a useful predictor for the diagnosis of bacterial meningitis. Moreover, levels of DcR3 are elevated in patients with Figure 1 Receiver operating characteristic (ROC) curves of DcR3 and sTREM-1 for the diagnosis of bacterial meningitis. In addition, because serum of patients in this study were not collected, predictive value of combined bioscore in blood for bacterial meningitis was not determined. In conclusion, this retrospective study demonstrated that combination of DcR3 and sTREM-1 in CSF could yielded a better diagnostic value for nosocomial bacterial meningitis than that of each biomarker. ./cache/cord-001583-le1mc045.txt ./txt/cord-001583-le1mc045.txt