id author title date pages extension mime words sentences flesch summary cache txt cord-348053-s0ijzyaq Mueller, Alisa A. Inflammatory biomarker trends predict respiratory decline in COVID-19 patients 2020-10-29 .txt text/plain 3732 185 47 In this single-center retrospective cohort analysis of hospitalized COVID-19 patients, we investigate whether inflammatory biomarker levels predict respiratory decline in patients who initially present with stable disease. We hypothesized that inflammatory biomarker profiles would stratify patients into three cohorts: (1) stable and non-intubated throughout their hospital admission ("mild"); (2) initially stable and nonintubated but then had respiratory deterioration requiring intubation or high-flow nasal cannula later in their hospital course ("progressive"); and (3) patients who were unstable and required intubation within 12 hours of admission ("severe"). We classified COVID-19 inpatients into three cohorts according to the stability and severity of their respiratory failure: 1) "Mild" (remained on room air or supplemental oxygen); 2) "Progressive" (initially on room air or supplemental oxygen then later required intubation or high-flow nasal cannula); or 3) "Severe" (required intubation within 12 hours of admission) ( Figure S1 and Table 1 ). ./cache/cord-348053-s0ijzyaq.txt ./txt/cord-348053-s0ijzyaq.txt