key: cord-296806-pep4vlj1
authors: Rotulo, Gioacchino Andrea; Signa, Sara; Rosina, Silvia; Pastorino, Carlotta; Bondi, Elisabetta; Maghnie, Mohamad
title: Giant Urticaria and Acral Peeling in a Child with COVID-19
date: 2020-10-21
journal: J Pediatr
DOI: 10.1016/j.jpeds.2020.10.039
sha: 
doc_id: 296806
cord_uid: pep4vlj1

nan

The fever disappeared quickly, lasting only 24 hours. Antihistamine therapy was given for symptomatic relief, with resolution of skin symptoms within four days. Mother and child were discharged in good general condition and continued isolation at home.

Several clinical cases of suspected COVID-19 with skin involvement have been described in pediatric age, but most of them were unconfirmed cases (Appendix).

The presence of acral peeling, not yet clearly described as a sign of COVID19, in association with giant urticaria, should be emphasized in our confirmed pediatric case.

Moreover, the skin manifestation was the first presenting sign of COVID-19, before the onset of fever. This must be taken into consideration to recognize a pediatric COVID-19 case early.

COVID toes"): Histologic, immunofluorescence, and immunohistochemical study of 17 cases

Timing of PCR and Antibody Testing in Patients with COVID-19 associated dermatologic manifestations

COVID-19 and cutaneous manifestations: a systematic review

All that glisters is not COVID: low prevalence of seroconversion against SARS-CoV-2 in a pediatric cohort of patients with Chilblain-like lesions

We thank Emilio Casalini, MD, and Stefania Santaniello, MD, for their support in this case as pediatricians in training.