key: cord-254776-m4makxr8
authors: Luo, Shiua; Guo, Yanrong; Zhang, Xiaochun; Xu, Haibo
title: A Follow-up Study of Recovered Patients with COVID-19 in Wuhan, China
date: 2020-06-01
journal: Int J Infect Dis
DOI: 10.1016/j.ijid.2020.05.119
sha: 
doc_id: 254776
cord_uid: m4makxr8

nan

The 2019 novel coronavirus disease (COVID-19) epidemic has clearly entered a new stage with rapid spread in countries outside China [1] . It has been declared a pandemic by the World Health Organization. The Chinese government has taken serious actions and made unremitted efforts in prevention and control of COVID-19 epidemic, including imposing quarantines and travel restrictions on an unprecedented scale and investing a huge amount of medical resources [2] . Currently, a large number of COVID-19 patients in Wuhan have been cured and discharged.

In Wuhan, China, all cured patients with COVID-19 are required to quarantine in either a designated hotel room or at home for 14 days [3] . They will return to normal J o u r n a l P r e -p r o o f social life after a follow-up by strictly eliminating the recurrence of COVID-19.

They will receive follow-up check-ups in a designated fever clinic, including physical examination, laboratory test including IgG and IgM antibody, C-reactive protein，the level of leukocyte and lymphocyte, and chest CT scan. At present, the outcome of these patients is not yet fully clear. We retrospectively evaluated the data of the recovered patients with COVID-19 in two different designated fever clinics in Wuhan, with a goal to provide relevant information about these patients. In this study, only 7.7‰ patients experienced recurrence during isolation and observation, and all presented with mild symptoms. No nosocomial transmission was found in this process. Serological tests to identify antibodies played a key role in surveillance of recurrence of COVID-19 [4] . The studies about viral shedding in discharged patients need further investigation.

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. 

SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients

WHO. Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19)

There is no funding source of this study.This study was approved by the Medical Ethical Committee of Zhongnan Hospital of Wuhan University.