id	sid	tid	token	lemma	pos
cord-345879-nbfg47x5	1	1	key	key	NN
cord-345879-nbfg47x5	1	2	:	:	:
cord-345879-nbfg47x5	1	3	cord-345879-nbfg47x5	cord-345879-nbfg47x5	CD
cord-345879-nbfg47x5	1	4	authors	author	NNS
cord-345879-nbfg47x5	1	5	:	:	:
cord-345879-nbfg47x5	1	6	Bonaz	Bonaz	NNP
cord-345879-nbfg47x5	1	7	,	,	,
cord-345879-nbfg47x5	1	8	Bruno	Bruno	NNP
cord-345879-nbfg47x5	1	9	;	;	:
cord-345879-nbfg47x5	1	10	Sinniger	Sinniger	NNP
cord-345879-nbfg47x5	1	11	,	,	,
cord-345879-nbfg47x5	1	12	Valérie	Valérie	NNP
cord-345879-nbfg47x5	1	13	;	;	:
cord-345879-nbfg47x5	1	14	Pellissier	Pellissier	NNP
cord-345879-nbfg47x5	1	15	,	,	,
cord-345879-nbfg47x5	1	16	Sonia	Sonia	NNP
cord-345879-nbfg47x5	1	17	title	title	NN
cord-345879-nbfg47x5	1	18	:	:	:
cord-345879-nbfg47x5	2	1	Targeting	target	VBG
cord-345879-nbfg47x5	2	2	the	the	DT
cord-345879-nbfg47x5	2	3	cholinergic	cholinergic	JJ
cord-345879-nbfg47x5	2	4	anti	anti	JJ
cord-345879-nbfg47x5	2	5	-	-	JJ
cord-345879-nbfg47x5	2	6	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	2	7	pathway	pathway	NN
cord-345879-nbfg47x5	2	8	with	with	IN
cord-345879-nbfg47x5	2	9	vagus	vagus	JJ
cord-345879-nbfg47x5	2	10	nerve	nerve	NN
cord-345879-nbfg47x5	2	11	stimulation	stimulation	NN
cord-345879-nbfg47x5	2	12	in	in	IN
cord-345879-nbfg47x5	2	13	patients	patient	NNS
cord-345879-nbfg47x5	2	14	with	with	IN
cord-345879-nbfg47x5	2	15	Covid-19	covid-19	NN
cord-345879-nbfg47x5	2	16	?	?	.
cord-345879-nbfg47x5	2	17	date	date	NN
cord-345879-nbfg47x5	2	18	:	:	:
cord-345879-nbfg47x5	2	19	2020	2020	CD
cord-345879-nbfg47x5	2	20	-	-	HYPH
cord-345879-nbfg47x5	2	21	07	07	CD
cord-345879-nbfg47x5	2	22	-	-	HYPH
cord-345879-nbfg47x5	2	23	29	29	CD
cord-345879-nbfg47x5	2	24	journal	journal	NN
cord-345879-nbfg47x5	2	25	:	:	:
cord-345879-nbfg47x5	3	1	Bioelectron	Bioelectron	NNP
cord-345879-nbfg47x5	3	2	Med	Med	NNP
cord-345879-nbfg47x5	3	3	DOI	DOI	NNP
cord-345879-nbfg47x5	3	4	:	:	:
cord-345879-nbfg47x5	3	5	10.1186	10.1186	CD
cord-345879-nbfg47x5	3	6	/	/	SYM
cord-345879-nbfg47x5	3	7	s42234	s42234	NN
cord-345879-nbfg47x5	3	8	-	-	HYPH
cord-345879-nbfg47x5	3	9	020	020	CD
cord-345879-nbfg47x5	3	10	-	-	HYPH
cord-345879-nbfg47x5	3	11	00051	00051	CD
cord-345879-nbfg47x5	3	12	-	-	SYM
cord-345879-nbfg47x5	3	13	7	7	CD
cord-345879-nbfg47x5	3	14	sha	sha	NN
cord-345879-nbfg47x5	3	15	:	:	:
cord-345879-nbfg47x5	4	1	c61d9b04d9f50e11b4893216b8185fea6b512726	c61d9b04d9f50e11b4893216b8185fea6b512726	NNP
cord-345879-nbfg47x5	4	2	doc_id	doc_id	CD
cord-345879-nbfg47x5	4	3	:	:	:
cord-345879-nbfg47x5	4	4	345879	345879	CD
cord-345879-nbfg47x5	4	5	cord_uid	cord_uid	FW
cord-345879-nbfg47x5	4	6	:	:	:
cord-345879-nbfg47x5	5	1	nbfg47x5	nbfg47x5	NNP
cord-345879-nbfg47x5	5	2	Severe	severe	JJ
cord-345879-nbfg47x5	5	3	acute	acute	JJ
cord-345879-nbfg47x5	5	4	respiratory	respiratory	JJ
cord-345879-nbfg47x5	5	5	syndrome	syndrome	NN
cord-345879-nbfg47x5	5	6	coronavirus	coronavirus	NN
cord-345879-nbfg47x5	5	7	2	2	CD
cord-345879-nbfg47x5	6	1	(	(	-LRB-
cord-345879-nbfg47x5	6	2	SARS	SARS	NNP
cord-345879-nbfg47x5	6	3	-	-	HYPH
cord-345879-nbfg47x5	6	4	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	6	5	)	)	-RRB-
cord-345879-nbfg47x5	6	6	,	,	,
cord-345879-nbfg47x5	6	7	at	at	IN
cord-345879-nbfg47x5	6	8	the	the	DT
cord-345879-nbfg47x5	6	9	origin	origin	NN
cord-345879-nbfg47x5	6	10	of	of	IN
cord-345879-nbfg47x5	6	11	the	the	DT
cord-345879-nbfg47x5	6	12	worldwide	worldwide	JJ
cord-345879-nbfg47x5	6	13	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	6	14	pandemic	pandemic	NN
cord-345879-nbfg47x5	6	15	,	,	,
cord-345879-nbfg47x5	6	16	is	be	VBZ
cord-345879-nbfg47x5	6	17	characterized	characterize	VBN
cord-345879-nbfg47x5	6	18	by	by	IN
cord-345879-nbfg47x5	6	19	a	a	DT
cord-345879-nbfg47x5	6	20	dramatic	dramatic	JJ
cord-345879-nbfg47x5	6	21	cytokine	cytokine	NN
cord-345879-nbfg47x5	6	22	storm	storm	NN
cord-345879-nbfg47x5	6	23	in	in	IN
cord-345879-nbfg47x5	6	24	some	some	DT
cord-345879-nbfg47x5	6	25	critical	critical	JJ
cord-345879-nbfg47x5	6	26	patients	patient	NNS
cord-345879-nbfg47x5	6	27	with	with	IN
cord-345879-nbfg47x5	6	28	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	6	29	.	.	.
cord-345879-nbfg47x5	7	1	This	this	DT
cord-345879-nbfg47x5	7	2	storm	storm	NN
cord-345879-nbfg47x5	7	3	is	be	VBZ
cord-345879-nbfg47x5	7	4	due	due	JJ
cord-345879-nbfg47x5	7	5	to	to	IN
cord-345879-nbfg47x5	7	6	the	the	DT
cord-345879-nbfg47x5	7	7	release	release	NN
cord-345879-nbfg47x5	7	8	of	of	IN
cord-345879-nbfg47x5	7	9	high	high	JJ
cord-345879-nbfg47x5	7	10	levels	level	NNS
cord-345879-nbfg47x5	7	11	of	of	IN
cord-345879-nbfg47x5	7	12	pro	pro	JJ
cord-345879-nbfg47x5	7	13	-	-	JJ
cord-345879-nbfg47x5	7	14	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	7	15	cytokines	cytokine	NNS
cord-345879-nbfg47x5	7	16	such	such	JJ
cord-345879-nbfg47x5	7	17	as	as	IN
cord-345879-nbfg47x5	7	18	interleukin	interleukin	NN
cord-345879-nbfg47x5	7	19	(	(	-LRB-
cord-345879-nbfg47x5	7	20	IL)-1	il)-1	IN
cord-345879-nbfg47x5	7	21	β	β	NN
cord-345879-nbfg47x5	7	22	,	,	,
cord-345879-nbfg47x5	7	23	IL-6	IL-6	NNP
cord-345879-nbfg47x5	7	24	,	,	,
cord-345879-nbfg47x5	7	25	tumor	tumor	NN
cord-345879-nbfg47x5	7	26	necrosis	necrosis	NN
cord-345879-nbfg47x5	7	27	factor	factor	NN
cord-345879-nbfg47x5	7	28	(	(	-LRB-
cord-345879-nbfg47x5	7	29	TNF	TNF	NNP
cord-345879-nbfg47x5	7	30	)	)	-RRB-
cord-345879-nbfg47x5	7	31	,	,	,
cord-345879-nbfg47x5	7	32	and	and	CC
cord-345879-nbfg47x5	7	33	chemokines	chemokine	NNS
cord-345879-nbfg47x5	7	34	by	by	IN
cord-345879-nbfg47x5	7	35	respiratory	respiratory	JJ
cord-345879-nbfg47x5	7	36	epithelial	epithelial	NN
cord-345879-nbfg47x5	7	37	and	and	CC
cord-345879-nbfg47x5	7	38	dendritic	dendritic	JJ
cord-345879-nbfg47x5	7	39	cells	cell	NNS
cord-345879-nbfg47x5	7	40	,	,	,
cord-345879-nbfg47x5	7	41	and	and	CC
cord-345879-nbfg47x5	7	42	macrophages	macrophage	NNS
cord-345879-nbfg47x5	7	43	.	.	.
cord-345879-nbfg47x5	8	1	We	-PRON-	PRP
cord-345879-nbfg47x5	8	2	hypothesize	hypothesize	VBP
cord-345879-nbfg47x5	8	3	that	that	IN
cord-345879-nbfg47x5	8	4	this	this	DT
cord-345879-nbfg47x5	8	5	cytokine	cytokine	NN
cord-345879-nbfg47x5	8	6	storm	storm	NN
cord-345879-nbfg47x5	8	7	and	and	CC
cord-345879-nbfg47x5	8	8	the	the	DT
cord-345879-nbfg47x5	8	9	worsening	worsening	NN
cord-345879-nbfg47x5	8	10	of	of	IN
cord-345879-nbfg47x5	8	11	patients	patient	NNS
cord-345879-nbfg47x5	8	12	’	’	POS
cord-345879-nbfg47x5	8	13	health	health	NN
cord-345879-nbfg47x5	8	14	status	status	NN
cord-345879-nbfg47x5	8	15	can	can	MD
cord-345879-nbfg47x5	8	16	be	be	VB
cord-345879-nbfg47x5	8	17	dampened	dampen	VBN
cord-345879-nbfg47x5	8	18	or	or	CC
cord-345879-nbfg47x5	8	19	even	even	RB
cord-345879-nbfg47x5	8	20	prevented	prevent	VBN
cord-345879-nbfg47x5	8	21	by	by	IN
cord-345879-nbfg47x5	8	22	specifically	specifically	RB
cord-345879-nbfg47x5	8	23	targeting	target	VBG
cord-345879-nbfg47x5	8	24	the	the	DT
cord-345879-nbfg47x5	8	25	vagal	vagal	RB
cord-345879-nbfg47x5	8	26	-	-	HYPH
cord-345879-nbfg47x5	8	27	driven	drive	VBN
cord-345879-nbfg47x5	8	28	cholinergic	cholinergic	JJ
cord-345879-nbfg47x5	8	29	anti	anti	JJ
cord-345879-nbfg47x5	8	30	-	-	JJ
cord-345879-nbfg47x5	8	31	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	8	32	pathway	pathway	NN
cord-345879-nbfg47x5	8	33	(	(	-LRB-
cord-345879-nbfg47x5	8	34	CAP	cap	NN
cord-345879-nbfg47x5	8	35	)	)	-RRB-
cord-345879-nbfg47x5	8	36	.	.	.
cord-345879-nbfg47x5	9	1	The	the	DT
cord-345879-nbfg47x5	9	2	CAP	cap	NN
cord-345879-nbfg47x5	9	3	is	be	VBZ
cord-345879-nbfg47x5	9	4	a	a	DT
cord-345879-nbfg47x5	9	5	concept	concept	NN
cord-345879-nbfg47x5	9	6	that	that	WDT
cord-345879-nbfg47x5	9	7	involves	involve	VBZ
cord-345879-nbfg47x5	9	8	an	an	DT
cord-345879-nbfg47x5	9	9	anti	anti	JJ
cord-345879-nbfg47x5	9	10	-	-	JJ
cord-345879-nbfg47x5	9	11	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	9	12	effect	effect	NN
cord-345879-nbfg47x5	9	13	of	of	IN
cord-345879-nbfg47x5	9	14	vagal	vagal	JJ
cord-345879-nbfg47x5	9	15	efferents	efferent	NNS
cord-345879-nbfg47x5	9	16	by	by	IN
cord-345879-nbfg47x5	9	17	the	the	DT
cord-345879-nbfg47x5	9	18	release	release	NN
cord-345879-nbfg47x5	9	19	of	of	IN
cord-345879-nbfg47x5	9	20	acetylcholine	acetylcholine	NN
cord-345879-nbfg47x5	9	21	(	(	-LRB-
cord-345879-nbfg47x5	9	22	ACh	ACh	NNP
cord-345879-nbfg47x5	9	23	)	)	-RRB-
cord-345879-nbfg47x5	9	24	.	.	.
cord-345879-nbfg47x5	10	1	Nicotinic	nicotinic	JJ
cord-345879-nbfg47x5	10	2	acetylcholine	acetylcholine	NN
cord-345879-nbfg47x5	10	3	receptor	receptor	NN
cord-345879-nbfg47x5	10	4	alpha7	alpha7	NN
cord-345879-nbfg47x5	10	5	subunit	subunit	NN
cord-345879-nbfg47x5	10	6	(	(	-LRB-
cord-345879-nbfg47x5	10	7	α7nAChRs	α7nachrs	XX
cord-345879-nbfg47x5	10	8	)	)	-RRB-
cord-345879-nbfg47x5	10	9	is	be	VBZ
cord-345879-nbfg47x5	10	10	required	require	VBN
cord-345879-nbfg47x5	10	11	for	for	IN
cord-345879-nbfg47x5	10	12	ACh	ACh	NNP
cord-345879-nbfg47x5	10	13	inhibition	inhibition	NN
cord-345879-nbfg47x5	10	14	of	of	IN
cord-345879-nbfg47x5	10	15	macrophage	macrophage	NN
cord-345879-nbfg47x5	10	16	-	-	HYPH
cord-345879-nbfg47x5	10	17	TNF	tnf	NN
cord-345879-nbfg47x5	10	18	release	release	NN
cord-345879-nbfg47x5	10	19	and	and	CC
cord-345879-nbfg47x5	10	20	cytokine	cytokine	NN
cord-345879-nbfg47x5	10	21	modulation	modulation	NN
cord-345879-nbfg47x5	10	22	.	.	.
cord-345879-nbfg47x5	11	1	Hence	hence	RB
cord-345879-nbfg47x5	11	2	,	,	,
cord-345879-nbfg47x5	11	3	targeting	target	VBG
cord-345879-nbfg47x5	11	4	the	the	DT
cord-345879-nbfg47x5	11	5	α7nAChRs	α7nachrs	XX
cord-345879-nbfg47x5	11	6	through	through	IN
cord-345879-nbfg47x5	11	7	vagus	vagus	JJ
cord-345879-nbfg47x5	11	8	nerve	nerve	NN
cord-345879-nbfg47x5	11	9	stimulation	stimulation	NN
cord-345879-nbfg47x5	11	10	(	(	-LRB-
cord-345879-nbfg47x5	11	11	VNS	VNS	NNP
cord-345879-nbfg47x5	11	12	)	)	-RRB-
cord-345879-nbfg47x5	11	13	could	could	MD
cord-345879-nbfg47x5	11	14	be	be	VB
cord-345879-nbfg47x5	11	15	of	of	IN
cord-345879-nbfg47x5	11	16	interest	interest	NN
cord-345879-nbfg47x5	11	17	in	in	IN
cord-345879-nbfg47x5	11	18	the	the	DT
cord-345879-nbfg47x5	11	19	management	management	NN
cord-345879-nbfg47x5	11	20	of	of	IN
cord-345879-nbfg47x5	11	21	patients	patient	NNS
cord-345879-nbfg47x5	11	22	with	with	IN
cord-345879-nbfg47x5	11	23	SARS	SARS	NNP
cord-345879-nbfg47x5	11	24	-	-	HYPH
cord-345879-nbfg47x5	11	25	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	11	26	infection	infection	NN
cord-345879-nbfg47x5	11	27	.	.	.
cord-345879-nbfg47x5	12	1	Indeed	indeed	RB
cord-345879-nbfg47x5	12	2	,	,	,
cord-345879-nbfg47x5	12	3	through	through	IN
cord-345879-nbfg47x5	12	4	the	the	DT
cord-345879-nbfg47x5	12	5	wide	wide	JJ
cord-345879-nbfg47x5	12	6	innervation	innervation	NN
cord-345879-nbfg47x5	12	7	of	of	IN
cord-345879-nbfg47x5	12	8	the	the	DT
cord-345879-nbfg47x5	12	9	organism	organism	NN
cord-345879-nbfg47x5	12	10	by	by	IN
cord-345879-nbfg47x5	12	11	the	the	DT
cord-345879-nbfg47x5	12	12	vagus	vagus	NN
cord-345879-nbfg47x5	12	13	nerve	nerve	NN
cord-345879-nbfg47x5	12	14	,	,	,
cord-345879-nbfg47x5	12	15	especially	especially	RB
cord-345879-nbfg47x5	12	16	the	the	DT
cord-345879-nbfg47x5	12	17	lungs	lung	NNS
cord-345879-nbfg47x5	12	18	and	and	CC
cord-345879-nbfg47x5	12	19	gastrointestinal	gastrointestinal	JJ
cord-345879-nbfg47x5	12	20	tract	tract	NN
cord-345879-nbfg47x5	12	21	,	,	,
cord-345879-nbfg47x5	12	22	VNS	VNS	NNP
cord-345879-nbfg47x5	12	23	appears	appear	VBZ
cord-345879-nbfg47x5	12	24	as	as	IN
cord-345879-nbfg47x5	12	25	a	a	DT
cord-345879-nbfg47x5	12	26	serious	serious	JJ
cord-345879-nbfg47x5	12	27	candidate	candidate	NN
cord-345879-nbfg47x5	12	28	for	for	IN
cord-345879-nbfg47x5	12	29	a	a	DT
cord-345879-nbfg47x5	12	30	few	few	JJ
cord-345879-nbfg47x5	12	31	side	side	NN
cord-345879-nbfg47x5	12	32	effect	effect	NN
cord-345879-nbfg47x5	12	33	treatment	treatment	NN
cord-345879-nbfg47x5	12	34	that	that	WDT
cord-345879-nbfg47x5	12	35	could	could	MD
cord-345879-nbfg47x5	12	36	dampen	dampen	VB
cord-345879-nbfg47x5	12	37	or	or	CC
cord-345879-nbfg47x5	12	38	prevent	prevent	VB
cord-345879-nbfg47x5	12	39	the	the	DT
cord-345879-nbfg47x5	12	40	cytokine	cytokine	NN
cord-345879-nbfg47x5	12	41	storm	storm	NN
cord-345879-nbfg47x5	12	42	observed	observe	VBD
cord-345879-nbfg47x5	12	43	in	in	IN
cord-345879-nbfg47x5	12	44	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	12	45	patients	patient	NNS
cord-345879-nbfg47x5	12	46	with	with	IN
cord-345879-nbfg47x5	12	47	severe	severe	JJ
cord-345879-nbfg47x5	12	48	symptoms	symptom	NNS
cord-345879-nbfg47x5	12	49	.	.	.
cord-345879-nbfg47x5	13	1	Finally	finally	RB
cord-345879-nbfg47x5	13	2	,	,	,
cord-345879-nbfg47x5	13	3	a	a	DT
cord-345879-nbfg47x5	13	4	continuous	continuous	JJ
cord-345879-nbfg47x5	13	5	vagal	vagal	JJ
cord-345879-nbfg47x5	13	6	tone	tone	NN
cord-345879-nbfg47x5	13	7	monitoring	monitoring	NN
cord-345879-nbfg47x5	13	8	in	in	IN
cord-345879-nbfg47x5	13	9	patients	patient	NNS
cord-345879-nbfg47x5	13	10	with	with	IN
cord-345879-nbfg47x5	13	11	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	13	12	could	could	MD
cord-345879-nbfg47x5	13	13	be	be	VB
cord-345879-nbfg47x5	13	14	used	use	VBN
cord-345879-nbfg47x5	13	15	as	as	IN
cord-345879-nbfg47x5	13	16	a	a	DT
cord-345879-nbfg47x5	13	17	predictive	predictive	JJ
cord-345879-nbfg47x5	13	18	marker	marker	NN
cord-345879-nbfg47x5	13	19	of	of	IN
cord-345879-nbfg47x5	13	20	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	13	21	illness	illness	NN
cord-345879-nbfg47x5	13	22	course	course	NN
cord-345879-nbfg47x5	13	23	but	but	CC
cord-345879-nbfg47x5	13	24	also	also	RB
cord-345879-nbfg47x5	13	25	as	as	IN
cord-345879-nbfg47x5	13	26	a	a	DT
cord-345879-nbfg47x5	13	27	predictive	predictive	JJ
cord-345879-nbfg47x5	13	28	marker	marker	NN
cord-345879-nbfg47x5	13	29	of	of	IN
cord-345879-nbfg47x5	13	30	response	response	NN
cord-345879-nbfg47x5	13	31	to	to	IN
cord-345879-nbfg47x5	13	32	COVID-19	covid-19	VB
cord-345879-nbfg47x5	13	33	treatment	treatment	NN
cord-345879-nbfg47x5	13	34	such	such	JJ
cord-345879-nbfg47x5	13	35	as	as	IN
cord-345879-nbfg47x5	13	36	VNS	VNS	NNP
cord-345879-nbfg47x5	13	37	or	or	CC
cord-345879-nbfg47x5	13	38	others	other	NNS
cord-345879-nbfg47x5	13	39	.	.	.
cord-345879-nbfg47x5	14	1	Severe	severe	JJ
cord-345879-nbfg47x5	14	2	acute	acute	JJ
cord-345879-nbfg47x5	14	3	respiratory	respiratory	JJ
cord-345879-nbfg47x5	14	4	syndrome	syndrome	NN
cord-345879-nbfg47x5	14	5	coronavirus	coronavirus	NN
cord-345879-nbfg47x5	14	6	2	2	CD
cord-345879-nbfg47x5	15	1	(	(	-LRB-
cord-345879-nbfg47x5	15	2	SARS	SARS	NNP
cord-345879-nbfg47x5	15	3	-	-	HYPH
cord-345879-nbfg47x5	15	4	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	15	5	)	)	-RRB-
cord-345879-nbfg47x5	15	6	first	first	RB
cord-345879-nbfg47x5	15	7	appeared	appear	VBD
cord-345879-nbfg47x5	15	8	in	in	IN
cord-345879-nbfg47x5	15	9	December	December	NNP
cord-345879-nbfg47x5	15	10	2019	2019	CD
cord-345879-nbfg47x5	15	11	,	,	,
cord-345879-nbfg47x5	15	12	in	in	IN
cord-345879-nbfg47x5	15	13	Wuhan	Wuhan	NNP
cord-345879-nbfg47x5	15	14	,	,	,
cord-345879-nbfg47x5	15	15	Hubei	Hubei	NNP
cord-345879-nbfg47x5	15	16	Province	Province	NNP
cord-345879-nbfg47x5	15	17	of	of	IN
cord-345879-nbfg47x5	15	18	China	China	NNP
cord-345879-nbfg47x5	15	19	,	,	,
cord-345879-nbfg47x5	15	20	and	and	CC
cord-345879-nbfg47x5	15	21	rapidly	rapidly	RB
cord-345879-nbfg47x5	15	22	spread	spread	VBD
cord-345879-nbfg47x5	15	23	in	in	IN
cord-345879-nbfg47x5	15	24	a	a	DT
cord-345879-nbfg47x5	15	25	worldwide	worldwide	JJ
cord-345879-nbfg47x5	15	26	pandemic	pandemic	NN
cord-345879-nbfg47x5	15	27	.	.	.
cord-345879-nbfg47x5	16	1	The	the	DT
cord-345879-nbfg47x5	16	2	vast	vast	JJ
cord-345879-nbfg47x5	16	3	majority	majority	NN
cord-345879-nbfg47x5	16	4	of	of	IN
cord-345879-nbfg47x5	16	5	patients	patient	NNS
cord-345879-nbfg47x5	16	6	with	with	IN
cord-345879-nbfg47x5	16	7	the	the	DT
cord-345879-nbfg47x5	16	8	coronavirus	coronavirus	NN
cord-345879-nbfg47x5	16	9	disease	disease	NN
cord-345879-nbfg47x5	16	10	2019	2019	CD
cord-345879-nbfg47x5	16	11	(	(	-LRB-
cord-345879-nbfg47x5	16	12	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	16	13	)	)	-RRB-
cord-345879-nbfg47x5	16	14	have	have	VB
cord-345879-nbfg47x5	16	15	a	a	DT
cord-345879-nbfg47x5	16	16	good	good	JJ
cord-345879-nbfg47x5	16	17	prognosis	prognosis	NN
cord-345879-nbfg47x5	16	18	.	.	.
cord-345879-nbfg47x5	17	1	Clinically	clinically	RB
cord-345879-nbfg47x5	17	2	,	,	,
cord-345879-nbfg47x5	17	3	SARS	SARS	NNP
cord-345879-nbfg47x5	17	4	-	-	HYPH
cord-345879-nbfg47x5	17	5	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	17	6	ranges	range	VBZ
cord-345879-nbfg47x5	17	7	from	from	IN
cord-345879-nbfg47x5	17	8	asymptomatic	asymptomatic	JJ
cord-345879-nbfg47x5	17	9	disease	disease	NN
cord-345879-nbfg47x5	17	10	to	to	IN
cord-345879-nbfg47x5	17	11	mild	mild	JJ
cord-345879-nbfg47x5	17	12	symptoms	symptom	NNS
cord-345879-nbfg47x5	17	13	such	such	JJ
cord-345879-nbfg47x5	17	14	as	as	IN
cord-345879-nbfg47x5	17	15	fever	fever	NN
cord-345879-nbfg47x5	17	16	,	,	,
cord-345879-nbfg47x5	17	17	sore	sore	JJ
cord-345879-nbfg47x5	17	18	throat	throat	NN
cord-345879-nbfg47x5	17	19	,	,	,
cord-345879-nbfg47x5	17	20	cough	cough	NN
cord-345879-nbfg47x5	17	21	,	,	,
cord-345879-nbfg47x5	17	22	loss	loss	NN
cord-345879-nbfg47x5	17	23	of	of	IN
cord-345879-nbfg47x5	17	24	smell	smell	NN
cord-345879-nbfg47x5	17	25	and	and	CC
cord-345879-nbfg47x5	17	26	taste	taste	NN
cord-345879-nbfg47x5	17	27	,	,	,
cord-345879-nbfg47x5	17	28	myalgia	myalgia	NN
cord-345879-nbfg47x5	17	29	,	,	,
cord-345879-nbfg47x5	17	30	headache	headache	NN
cord-345879-nbfg47x5	17	31	,	,	,
cord-345879-nbfg47x5	17	32	fatigue	fatigue	NN
cord-345879-nbfg47x5	17	33	,	,	,
cord-345879-nbfg47x5	17	34	to	to	IN
cord-345879-nbfg47x5	17	35	severe	severe	JJ
cord-345879-nbfg47x5	17	36	pneumonia	pneumonia	NN
cord-345879-nbfg47x5	17	37	with	with	IN
cord-345879-nbfg47x5	17	38	respiratory	respiratory	JJ
cord-345879-nbfg47x5	17	39	failure	failure	NN
cord-345879-nbfg47x5	17	40	,	,	,
cord-345879-nbfg47x5	17	41	acute	acute	JJ
cord-345879-nbfg47x5	17	42	kidney	kidney	NN
cord-345879-nbfg47x5	17	43	and/or	and/or	CC
cord-345879-nbfg47x5	17	44	cardiac	cardiac	JJ
cord-345879-nbfg47x5	17	45	injury	injury	NN
cord-345879-nbfg47x5	17	46	,	,	,
cord-345879-nbfg47x5	17	47	and	and	CC
cord-345879-nbfg47x5	17	48	death	death	NN
cord-345879-nbfg47x5	18	1	(	(	-LRB-
cord-345879-nbfg47x5	18	2	Huang	Huang	NNP
cord-345879-nbfg47x5	18	3	et	et	NNP
cord-345879-nbfg47x5	18	4	al	al	NNP
cord-345879-nbfg47x5	18	5	.	.	NNP
cord-345879-nbfg47x5	18	6	2020	2020	CD
cord-345879-nbfg47x5	18	7	)	)	-RRB-
cord-345879-nbfg47x5	18	8	.	.	.
cord-345879-nbfg47x5	19	1	Digestive	digestive	JJ
cord-345879-nbfg47x5	19	2	manifestations	manifestation	NNS
cord-345879-nbfg47x5	19	3	such	such	JJ
cord-345879-nbfg47x5	19	4	as	as	IN
cord-345879-nbfg47x5	19	5	nausea	nausea	NN
cord-345879-nbfg47x5	19	6	,	,	,
cord-345879-nbfg47x5	19	7	vomiting	vomiting	NN
cord-345879-nbfg47x5	19	8	,	,	,
cord-345879-nbfg47x5	19	9	diarrhea	diarrhea	NN
cord-345879-nbfg47x5	19	10	,	,	,
cord-345879-nbfg47x5	19	11	are	be	VBP
cord-345879-nbfg47x5	19	12	also	also	RB
cord-345879-nbfg47x5	19	13	reported	report	VBN
cord-345879-nbfg47x5	19	14	(	(	-LRB-
cord-345879-nbfg47x5	19	15	Pan	Pan	NNP
cord-345879-nbfg47x5	19	16	et	et	FW
cord-345879-nbfg47x5	19	17	al	al	NNP
cord-345879-nbfg47x5	19	18	.	.	NNP
cord-345879-nbfg47x5	19	19	2020	2020	CD
cord-345879-nbfg47x5	19	20	)	)	-RRB-
cord-345879-nbfg47x5	19	21	.	.	.
cord-345879-nbfg47x5	20	1	Transmission	transmission	NN
cord-345879-nbfg47x5	20	2	of	of	IN
cord-345879-nbfg47x5	20	3	the	the	DT
cord-345879-nbfg47x5	20	4	virus	virus	NN
cord-345879-nbfg47x5	20	5	occurs	occur	VBZ
cord-345879-nbfg47x5	20	6	mainly	mainly	RB
cord-345879-nbfg47x5	20	7	through	through	IN
cord-345879-nbfg47x5	20	8	respiratory	respiratory	JJ
cord-345879-nbfg47x5	20	9	droplets	droplet	NNS
cord-345879-nbfg47x5	20	10	.	.	.
cord-345879-nbfg47x5	21	1	SARSCoV-2	SARSCoV-2	NNP
cord-345879-nbfg47x5	22	1	RNA	RNA	NNP
cord-345879-nbfg47x5	22	2	has	have	VBZ
cord-345879-nbfg47x5	22	3	been	be	VBN
cord-345879-nbfg47x5	22	4	isolated	isolate	VBN
cord-345879-nbfg47x5	22	5	in	in	IN
cord-345879-nbfg47x5	22	6	nasopharyngeal	nasopharyngeal	JJ
cord-345879-nbfg47x5	22	7	swabs	swab	NNS
cord-345879-nbfg47x5	22	8	,	,	,
cord-345879-nbfg47x5	22	9	sputum	sputum	NN
cord-345879-nbfg47x5	22	10	,	,	,
cord-345879-nbfg47x5	22	11	and	and	CC
cord-345879-nbfg47x5	22	12	in	in	IN
cord-345879-nbfg47x5	22	13	stool	stool	NN
cord-345879-nbfg47x5	22	14	samples	sample	NNS
cord-345879-nbfg47x5	22	15	.	.	.
cord-345879-nbfg47x5	23	1	This	this	DT
cord-345879-nbfg47x5	23	2	virus	virus	NN
cord-345879-nbfg47x5	23	3	can	can	MD
cord-345879-nbfg47x5	23	4	attack	attack	VB
cord-345879-nbfg47x5	23	5	lung	lung	NN
cord-345879-nbfg47x5	23	6	cells	cell	NNS
cord-345879-nbfg47x5	23	7	by	by	IN
cord-345879-nbfg47x5	23	8	binding	bind	VBG
cord-345879-nbfg47x5	23	9	to	to	IN
cord-345879-nbfg47x5	23	10	the	the	DT
cord-345879-nbfg47x5	23	11	Angiotensin	Angiotensin	NNP
cord-345879-nbfg47x5	23	12	Converting	Converting	NNP
cord-345879-nbfg47x5	23	13	Enzyme-2	Enzyme-2	NNP
cord-345879-nbfg47x5	23	14	(	(	-LRB-
cord-345879-nbfg47x5	23	15	ACE2	ACE2	NNP
cord-345879-nbfg47x5	23	16	)	)	-RRB-
cord-345879-nbfg47x5	23	17	receptor	receptor	NN
cord-345879-nbfg47x5	23	18	,	,	,
cord-345879-nbfg47x5	23	19	and	and	CC
cord-345879-nbfg47x5	23	20	its	-PRON-	PRP$
cord-345879-nbfg47x5	23	21	presence	presence	NN
cord-345879-nbfg47x5	23	22	in	in	IN
cord-345879-nbfg47x5	23	23	host	host	NN
cord-345879-nbfg47x5	23	24	cells	cell	NNS
cord-345879-nbfg47x5	23	25	will	will	MD
cord-345879-nbfg47x5	23	26	initiate	initiate	VB
cord-345879-nbfg47x5	23	27	various	various	JJ
cord-345879-nbfg47x5	23	28	defensive	defensive	JJ
cord-345879-nbfg47x5	23	29	responses	response	NNS
cord-345879-nbfg47x5	23	30	leading	lead	VBG
cord-345879-nbfg47x5	23	31	to	to	IN
cord-345879-nbfg47x5	23	32	pneumonia	pneumonia	NN
cord-345879-nbfg47x5	23	33	and	and	CC
cord-345879-nbfg47x5	23	34	acute	acute	JJ
cord-345879-nbfg47x5	23	35	respiratory	respiratory	JJ
cord-345879-nbfg47x5	23	36	distress	distress	NN
cord-345879-nbfg47x5	23	37	syndrome	syndrome	NN
cord-345879-nbfg47x5	23	38	.	.	.
cord-345879-nbfg47x5	24	1	ACE2	ACE2	NNP
cord-345879-nbfg47x5	24	2	is	be	VBZ
cord-345879-nbfg47x5	24	3	also	also	RB
cord-345879-nbfg47x5	24	4	present	present	JJ
cord-345879-nbfg47x5	24	5	in	in	IN
cord-345879-nbfg47x5	24	6	enterocytes	enterocyte	NNS
cord-345879-nbfg47x5	24	7	of	of	IN
cord-345879-nbfg47x5	24	8	the	the	DT
cord-345879-nbfg47x5	24	9	small	small	JJ
cord-345879-nbfg47x5	24	10	intestine	intestine	NN
cord-345879-nbfg47x5	24	11	thus	thus	RB
cord-345879-nbfg47x5	24	12	explaining	explain	VBG
cord-345879-nbfg47x5	24	13	the	the	DT
cord-345879-nbfg47x5	24	14	digestive	digestive	JJ
cord-345879-nbfg47x5	24	15	manifestations	manifestation	NNS
cord-345879-nbfg47x5	24	16	(	(	-LRB-
cord-345879-nbfg47x5	24	17	Zhang	Zhang	NNP
cord-345879-nbfg47x5	24	18	et	et	NNP
cord-345879-nbfg47x5	24	19	al	al	NNP
cord-345879-nbfg47x5	24	20	.	.	NNP
cord-345879-nbfg47x5	24	21	2020	2020	CD
cord-345879-nbfg47x5	24	22	)	)	-RRB-
cord-345879-nbfg47x5	24	23	.	.	.
cord-345879-nbfg47x5	25	1	The	the	DT
cord-345879-nbfg47x5	25	2	complex	complex	JJ
cord-345879-nbfg47x5	25	3	SARS	SARS	NNP
cord-345879-nbfg47x5	25	4	spike	spike	NN
cord-345879-nbfg47x5	25	5	protein	protein	NN
cord-345879-nbfg47x5	25	6	-	-	:
cord-345879-nbfg47x5	25	7	ACE2	ACE2	NNP
cord-345879-nbfg47x5	25	8	is	be	VBZ
cord-345879-nbfg47x5	25	9	proteolytically	proteolytically	RB
cord-345879-nbfg47x5	25	10	processed	process	VBN
cord-345879-nbfg47x5	25	11	by	by	IN
cord-345879-nbfg47x5	25	12	the	the	DT
cord-345879-nbfg47x5	25	13	transmembrane	transmembrane	NN
cord-345879-nbfg47x5	25	14	serine	serine	NN
cord-345879-nbfg47x5	25	15	protease	protease	NN
cord-345879-nbfg47x5	25	16	2	2	CD
cord-345879-nbfg47x5	25	17	leading	lead	VBG
cord-345879-nbfg47x5	25	18	to	to	IN
cord-345879-nbfg47x5	25	19	cleavage	cleavage	NN
cord-345879-nbfg47x5	25	20	of	of	IN
cord-345879-nbfg47x5	25	21	ACE2	ACE2	NNP
cord-345879-nbfg47x5	25	22	and	and	CC
cord-345879-nbfg47x5	25	23	activation	activation	NN
cord-345879-nbfg47x5	25	24	of	of	IN
cord-345879-nbfg47x5	25	25	the	the	DT
cord-345879-nbfg47x5	25	26	spike	spike	NN
cord-345879-nbfg47x5	25	27	protein	protein	NN
cord-345879-nbfg47x5	25	28	,	,	,
cord-345879-nbfg47x5	25	29	which	which	WDT
cord-345879-nbfg47x5	25	30	facilitates	facilitate	VBZ
cord-345879-nbfg47x5	25	31	viral	viral	JJ
cord-345879-nbfg47x5	25	32	entry	entry	NN
cord-345879-nbfg47x5	25	33	into	into	IN
cord-345879-nbfg47x5	25	34	the	the	DT
cord-345879-nbfg47x5	25	35	target	target	NN
cord-345879-nbfg47x5	25	36	cell	cell	NN
cord-345879-nbfg47x5	26	1	(	(	-LRB-
cord-345879-nbfg47x5	26	2	Hoffmann	Hoffmann	NNP
cord-345879-nbfg47x5	26	3	et	et	NNP
cord-345879-nbfg47x5	26	4	al	al	NNP
cord-345879-nbfg47x5	26	5	.	.	NNP
cord-345879-nbfg47x5	26	6	2020	2020	CD
cord-345879-nbfg47x5	26	7	)	)	-RRB-
cord-345879-nbfg47x5	26	8	.	.	.
cord-345879-nbfg47x5	27	1	Aging	age	VBG
cord-345879-nbfg47x5	27	2	,	,	,
cord-345879-nbfg47x5	27	3	male	male	JJ
cord-345879-nbfg47x5	27	4	gender	gender	NN
cord-345879-nbfg47x5	27	5	,	,	,
cord-345879-nbfg47x5	27	6	obesity	obesity	NN
cord-345879-nbfg47x5	27	7	,	,	,
cord-345879-nbfg47x5	27	8	diabetes	diabetes	NN
cord-345879-nbfg47x5	27	9	,	,	,
cord-345879-nbfg47x5	27	10	cardiovascular	cardiovascular	JJ
cord-345879-nbfg47x5	27	11	,	,	,
cord-345879-nbfg47x5	27	12	kidney	kidney	NN
cord-345879-nbfg47x5	27	13	,	,	,
cord-345879-nbfg47x5	27	14	and	and	CC
cord-345879-nbfg47x5	27	15	respiratory	respiratory	JJ
cord-345879-nbfg47x5	27	16	diseases	disease	NNS
cord-345879-nbfg47x5	27	17	are	be	VBP
cord-345879-nbfg47x5	27	18	major	major	JJ
cord-345879-nbfg47x5	27	19	aggravating	aggravating	JJ
cord-345879-nbfg47x5	27	20	factors	factor	NNS
cord-345879-nbfg47x5	27	21	for	for	IN
cord-345879-nbfg47x5	27	22	SARS	SARS	NNP
cord-345879-nbfg47x5	27	23	-	-	HYPH
cord-345879-nbfg47x5	27	24	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	27	25	infection	infection	NN
cord-345879-nbfg47x5	27	26	.	.	.
cord-345879-nbfg47x5	28	1	Proinflammatory	proinflammatory	NN
cord-345879-nbfg47x5	28	2	responses	response	NNS
cord-345879-nbfg47x5	28	3	play	play	VBP
cord-345879-nbfg47x5	28	4	a	a	DT
cord-345879-nbfg47x5	28	5	role	role	NN
cord-345879-nbfg47x5	28	6	in	in	IN
cord-345879-nbfg47x5	28	7	the	the	DT
cord-345879-nbfg47x5	28	8	pathogenesis	pathogenesis	NN
cord-345879-nbfg47x5	28	9	of	of	IN
cord-345879-nbfg47x5	28	10	human	human	JJ
cord-345879-nbfg47x5	28	11	coronavirus	coronavirus	NN
cord-345879-nbfg47x5	28	12	.	.	.
cord-345879-nbfg47x5	29	1	In	in	IN
cord-345879-nbfg47x5	29	2	vitro	vitro	FW
cord-345879-nbfg47x5	29	3	cell	cell	NN
cord-345879-nbfg47x5	29	4	experiments	experiment	NNS
cord-345879-nbfg47x5	29	5	have	have	VBP
cord-345879-nbfg47x5	29	6	shown	show	VBN
cord-345879-nbfg47x5	29	7	that	that	IN
cord-345879-nbfg47x5	29	8	delayed	delay	VBN
cord-345879-nbfg47x5	29	9	release	release	NN
cord-345879-nbfg47x5	29	10	of	of	IN
cord-345879-nbfg47x5	29	11	cytokines	cytokine	NNS
cord-345879-nbfg47x5	29	12	and	and	CC
cord-345879-nbfg47x5	29	13	chemokines	chemokine	NNS
cord-345879-nbfg47x5	29	14	occurs	occur	VBZ
cord-345879-nbfg47x5	29	15	in	in	IN
cord-345879-nbfg47x5	29	16	respiratory	respiratory	JJ
cord-345879-nbfg47x5	29	17	epithelial	epithelial	JJ
cord-345879-nbfg47x5	29	18	cells	cell	NNS
cord-345879-nbfg47x5	29	19	,	,	,
cord-345879-nbfg47x5	29	20	dendritic	dendritic	JJ
cord-345879-nbfg47x5	29	21	cells	cell	NNS
cord-345879-nbfg47x5	29	22	,	,	,
cord-345879-nbfg47x5	29	23	and	and	CC
cord-345879-nbfg47x5	29	24	macrophages	macrophage	NNS
cord-345879-nbfg47x5	29	25	at	at	IN
cord-345879-nbfg47x5	29	26	the	the	DT
cord-345879-nbfg47x5	29	27	early	early	JJ
cord-345879-nbfg47x5	29	28	stage	stage	NN
cord-345879-nbfg47x5	29	29	of	of	IN
cord-345879-nbfg47x5	29	30	SARS	SARS	NNP
cord-345879-nbfg47x5	29	31	-	-	HYPH
cord-345879-nbfg47x5	29	32	CoV	CoV	NNP
cord-345879-nbfg47x5	29	33	infection	infection	NN
cord-345879-nbfg47x5	29	34	.	.	.
cord-345879-nbfg47x5	30	1	Later	later	RB
cord-345879-nbfg47x5	30	2	,	,	,
cord-345879-nbfg47x5	30	3	the	the	DT
cord-345879-nbfg47x5	30	4	cells	cell	NNS
cord-345879-nbfg47x5	30	5	secrete	secrete	VBP
cord-345879-nbfg47x5	30	6	low	low	JJ
cord-345879-nbfg47x5	30	7	levels	level	NNS
cord-345879-nbfg47x5	30	8	of	of	IN
cord-345879-nbfg47x5	30	9	the	the	DT
cord-345879-nbfg47x5	30	10	antiviral	antiviral	JJ
cord-345879-nbfg47x5	30	11	factors	factor	NNS
cord-345879-nbfg47x5	30	12	interferons	interferon	NNS
cord-345879-nbfg47x5	30	13	and	and	CC
cord-345879-nbfg47x5	30	14	high	high	JJ
cord-345879-nbfg47x5	30	15	levels	level	NNS
cord-345879-nbfg47x5	30	16	of	of	IN
cord-345879-nbfg47x5	30	17	proinflammatory	proinflammatory	JJ
cord-345879-nbfg47x5	30	18	cytokines	cytokine	NNS
cord-345879-nbfg47x5	30	19	(	(	-LRB-
cord-345879-nbfg47x5	31	1	IL-1	IL-1	NNP
cord-345879-nbfg47x5	31	2	β	β	NNP
cord-345879-nbfg47x5	31	3	,	,	,
cord-345879-nbfg47x5	31	4	IL-6	IL-6	NNP
cord-345879-nbfg47x5	31	5	,	,	,
cord-345879-nbfg47x5	31	6	and	and	CC
cord-345879-nbfg47x5	31	7	TNF	TNF	NNP
cord-345879-nbfg47x5	31	8	)	)	-RRB-
cord-345879-nbfg47x5	31	9	and	and	CC
cord-345879-nbfg47x5	31	10	chemokines	chemokine	NNS
cord-345879-nbfg47x5	31	11	(	(	-LRB-
cord-345879-nbfg47x5	31	12	CCL-2	CCL-2	NNP
cord-345879-nbfg47x5	31	13	,	,	,
cord-345879-nbfg47x5	31	14	CCL-3	CCL-3	NNP
cord-345879-nbfg47x5	31	15	,	,	,
cord-345879-nbfg47x5	31	16	and	and	CC
cord-345879-nbfg47x5	31	17	CCL-5	CCL-5	NNP
cord-345879-nbfg47x5	31	18	)	)	-RRB-
cord-345879-nbfg47x5	31	19	(	(	-LRB-
cord-345879-nbfg47x5	31	20	Ye	Ye	NNP
cord-345879-nbfg47x5	31	21	et	et	FW
cord-345879-nbfg47x5	31	22	al	al	NNP
cord-345879-nbfg47x5	31	23	.	.	NNP
cord-345879-nbfg47x5	31	24	2020	2020	CD
cord-345879-nbfg47x5	31	25	)	)	-RRB-
cord-345879-nbfg47x5	31	26	.	.	.
cord-345879-nbfg47x5	32	1	Clinical	clinical	JJ
cord-345879-nbfg47x5	32	2	studies	study	NNS
cord-345879-nbfg47x5	32	3	have	have	VBP
cord-345879-nbfg47x5	32	4	detected	detect	VBN
cord-345879-nbfg47x5	32	5	such	such	PDT
cord-345879-nbfg47x5	32	6	a	a	DT
cord-345879-nbfg47x5	32	7	cytokine	cytokine	NN
cord-345879-nbfg47x5	32	8	storm	storm	NN
cord-345879-nbfg47x5	32	9	in	in	IN
cord-345879-nbfg47x5	32	10	critical	critical	JJ
cord-345879-nbfg47x5	32	11	patients	patient	NNS
cord-345879-nbfg47x5	32	12	with	with	IN
cord-345879-nbfg47x5	32	13	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	32	14	which	which	WDT
cord-345879-nbfg47x5	32	15	can	can	MD
cord-345879-nbfg47x5	32	16	result	result	VB
cord-345879-nbfg47x5	32	17	in	in	IN
cord-345879-nbfg47x5	32	18	acute	acute	JJ
cord-345879-nbfg47x5	32	19	lung	lung	NN
cord-345879-nbfg47x5	32	20	injury	injury	NN
cord-345879-nbfg47x5	32	21	and	and	CC
cord-345879-nbfg47x5	32	22	further	further	JJ
cord-345879-nbfg47x5	32	23	progress	progress	NN
cord-345879-nbfg47x5	32	24	to	to	IN
cord-345879-nbfg47x5	32	25	acute	acute	JJ
cord-345879-nbfg47x5	32	26	respiratory	respiratory	JJ
cord-345879-nbfg47x5	32	27	distress	distress	NN
cord-345879-nbfg47x5	32	28	syndrome	syndrome	NN
cord-345879-nbfg47x5	33	1	(	(	-LRB-
cord-345879-nbfg47x5	33	2	Ye	Ye	NNP
cord-345879-nbfg47x5	33	3	et	et	NNP
cord-345879-nbfg47x5	33	4	al	al	NNP
cord-345879-nbfg47x5	33	5	.	.	NNP
cord-345879-nbfg47x5	33	6	2020	2020	CD
cord-345879-nbfg47x5	33	7	)	)	-RRB-
cord-345879-nbfg47x5	33	8	.	.	.
cord-345879-nbfg47x5	34	1	Thus	thus	RB
cord-345879-nbfg47x5	34	2	,	,	,
cord-345879-nbfg47x5	34	3	controlling	control	VBG
cord-345879-nbfg47x5	34	4	or	or	CC
cord-345879-nbfg47x5	34	5	preventing	prevent	VBG
cord-345879-nbfg47x5	34	6	the	the	DT
cord-345879-nbfg47x5	34	7	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	34	8	response	response	NN
cord-345879-nbfg47x5	34	9	may	may	MD
cord-345879-nbfg47x5	34	10	be	be	VB
cord-345879-nbfg47x5	34	11	an	an	DT
cord-345879-nbfg47x5	34	12	effective	effective	JJ
cord-345879-nbfg47x5	34	13	way	way	NN
cord-345879-nbfg47x5	34	14	of	of	IN
cord-345879-nbfg47x5	34	15	preventing	prevent	VBG
cord-345879-nbfg47x5	34	16	collateral	collateral	JJ
cord-345879-nbfg47x5	34	17	damage	damage	NN
cord-345879-nbfg47x5	34	18	caused	cause	VBN
cord-345879-nbfg47x5	34	19	by	by	IN
cord-345879-nbfg47x5	34	20	the	the	DT
cord-345879-nbfg47x5	34	21	excessive	excessive	JJ
cord-345879-nbfg47x5	34	22	activation	activation	NN
cord-345879-nbfg47x5	34	23	of	of	IN
cord-345879-nbfg47x5	34	24	the	the	DT
cord-345879-nbfg47x5	34	25	immune	immune	JJ
cord-345879-nbfg47x5	34	26	system	system	NN
cord-345879-nbfg47x5	34	27	to	to	TO
cord-345879-nbfg47x5	34	28	clear	clear	JJ
cord-345879-nbfg47x5	34	29	pathogens	pathogen	NNS
cord-345879-nbfg47x5	34	30	.	.	.
cord-345879-nbfg47x5	35	1	In	in	IN
cord-345879-nbfg47x5	35	2	2000	2000	CD
cord-345879-nbfg47x5	35	3	,	,	,
cord-345879-nbfg47x5	35	4	the	the	DT
cord-345879-nbfg47x5	35	5	Tracey	Tracey	NNP
cord-345879-nbfg47x5	35	6	group	group	NN
cord-345879-nbfg47x5	35	7	introduced	introduce	VBD
cord-345879-nbfg47x5	35	8	the	the	DT
cord-345879-nbfg47x5	35	9	concept	concept	NN
cord-345879-nbfg47x5	35	10	of	of	IN
cord-345879-nbfg47x5	35	11	the	the	DT
cord-345879-nbfg47x5	35	12	cholinergic	cholinergic	JJ
cord-345879-nbfg47x5	35	13	anti	anti	JJ
cord-345879-nbfg47x5	35	14	-	-	JJ
cord-345879-nbfg47x5	35	15	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	35	16	pathway	pathway	NN
cord-345879-nbfg47x5	35	17	(	(	-LRB-
cord-345879-nbfg47x5	35	18	CAP	cap	NN
cord-345879-nbfg47x5	35	19	)	)	-RRB-
cord-345879-nbfg47x5	35	20	.	.	.
cord-345879-nbfg47x5	36	1	Indeed	indeed	RB
cord-345879-nbfg47x5	36	2	,	,	,
cord-345879-nbfg47x5	36	3	a	a	DT
cord-345879-nbfg47x5	36	4	septic	septic	JJ
cord-345879-nbfg47x5	36	5	shock	shock	NN
cord-345879-nbfg47x5	36	6	-	-	HYPH
cord-345879-nbfg47x5	36	7	induced	induce	VBN
cord-345879-nbfg47x5	36	8	increase	increase	NN
cord-345879-nbfg47x5	36	9	of	of	IN
cord-345879-nbfg47x5	36	10	TNF	TNF	NNP
cord-345879-nbfg47x5	36	11	in	in	IN
cord-345879-nbfg47x5	36	12	the	the	DT
cord-345879-nbfg47x5	36	13	liver	liver	NN
cord-345879-nbfg47x5	36	14	and	and	CC
cord-345879-nbfg47x5	36	15	the	the	DT
cord-345879-nbfg47x5	36	16	blood	blood	NN
cord-345879-nbfg47x5	36	17	in	in	IN
cord-345879-nbfg47x5	36	18	mice	mouse	NNS
cord-345879-nbfg47x5	36	19	was	be	VBD
cord-345879-nbfg47x5	36	20	dampened	dampen	VBN
cord-345879-nbfg47x5	36	21	by	by	IN
cord-345879-nbfg47x5	36	22	stimulation	stimulation	NN
cord-345879-nbfg47x5	36	23	of	of	IN
cord-345879-nbfg47x5	36	24	the	the	DT
cord-345879-nbfg47x5	36	25	distal	distal	JJ
cord-345879-nbfg47x5	36	26	end	end	NN
cord-345879-nbfg47x5	36	27	cut	cut	VBN
cord-345879-nbfg47x5	36	28	of	of	IN
cord-345879-nbfg47x5	36	29	the	the	DT
cord-345879-nbfg47x5	36	30	vagus	vagus	NN
cord-345879-nbfg47x5	36	31	nerve	nerve	NN
cord-345879-nbfg47x5	36	32	thus	thus	RB
cord-345879-nbfg47x5	36	33	arguing	argue	VBG
cord-345879-nbfg47x5	36	34	for	for	IN
cord-345879-nbfg47x5	36	35	an	an	DT
cord-345879-nbfg47x5	36	36	anti	anti	JJ
cord-345879-nbfg47x5	36	37	-	-	JJ
cord-345879-nbfg47x5	36	38	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	36	39	effect	effect	NN
cord-345879-nbfg47x5	36	40	of	of	IN
cord-345879-nbfg47x5	36	41	vagal	vagal	JJ
cord-345879-nbfg47x5	36	42	efferents	efferent	NNS
cord-345879-nbfg47x5	36	43	which	which	WDT
cord-345879-nbfg47x5	36	44	release	release	VBP
cord-345879-nbfg47x5	36	45	acetylcholine	acetylcholine	NN
cord-345879-nbfg47x5	36	46	(	(	-LRB-
cord-345879-nbfg47x5	36	47	ACh	ACh	NNP
cord-345879-nbfg47x5	36	48	)	)	-RRB-
cord-345879-nbfg47x5	37	1	(	(	-LRB-
cord-345879-nbfg47x5	37	2	Borovikova	Borovikova	NNP
cord-345879-nbfg47x5	37	3	et	et	NNP
cord-345879-nbfg47x5	37	4	al	al	NNP
cord-345879-nbfg47x5	37	5	.	.	.
cord-345879-nbfg47x5	37	6	2000	2000	CD
cord-345879-nbfg47x5	37	7	)	)	-RRB-
cord-345879-nbfg47x5	37	8	.	.	.
cord-345879-nbfg47x5	38	1	This	this	DT
cord-345879-nbfg47x5	38	2	group	group	NN
cord-345879-nbfg47x5	38	3	showed	show	VBD
cord-345879-nbfg47x5	38	4	that	that	IN
cord-345879-nbfg47x5	38	5	nicotinic	nicotinic	NNP
cord-345879-nbfg47x5	38	6	ACh	ACh	NNP
cord-345879-nbfg47x5	38	7	receptor	receptor	NN
cord-345879-nbfg47x5	38	8	alpha7	alpha7	NN
cord-345879-nbfg47x5	38	9	subunit	subunit	NN
cord-345879-nbfg47x5	38	10	(	(	-LRB-
cord-345879-nbfg47x5	38	11	α7nAChRs	α7nachrs	XX
cord-345879-nbfg47x5	38	12	)	)	-RRB-
cord-345879-nbfg47x5	38	13	is	be	VBZ
cord-345879-nbfg47x5	38	14	required	require	VBN
cord-345879-nbfg47x5	38	15	for	for	IN
cord-345879-nbfg47x5	38	16	ACh	ACh	NNP
cord-345879-nbfg47x5	38	17	inhibition	inhibition	NN
cord-345879-nbfg47x5	38	18	of	of	IN
cord-345879-nbfg47x5	38	19	macrophage	macrophage	NN
cord-345879-nbfg47x5	38	20	TNF	TNF	NNP
cord-345879-nbfg47x5	38	21	release	release	NN
cord-345879-nbfg47x5	38	22	(	(	-LRB-
cord-345879-nbfg47x5	38	23	Wang	Wang	NNP
cord-345879-nbfg47x5	38	24	et	et	NNP
cord-345879-nbfg47x5	38	25	al	al	NNP
cord-345879-nbfg47x5	38	26	.	.	NNP
cord-345879-nbfg47x5	38	27	2003	2003	CD
cord-345879-nbfg47x5	38	28	)	)	-RRB-
cord-345879-nbfg47x5	38	29	.	.	.
cord-345879-nbfg47x5	39	1	Besides	besides	IN
cord-345879-nbfg47x5	39	2	TNF	TNF	NNP
cord-345879-nbfg47x5	39	3	,	,	,
cord-345879-nbfg47x5	39	4	other	other	JJ
cord-345879-nbfg47x5	39	5	pro	pro	JJ
cord-345879-nbfg47x5	39	6	-	-	JJ
cord-345879-nbfg47x5	39	7	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	39	8	cytokines	cytokine	NNS
cord-345879-nbfg47x5	39	9	such	such	JJ
cord-345879-nbfg47x5	39	10	as	as	IN
cord-345879-nbfg47x5	39	11	IL6	IL6	NNP
cord-345879-nbfg47x5	39	12	,	,	,
cord-345879-nbfg47x5	39	13	IL1β	IL1β	NNP
cord-345879-nbfg47x5	39	14	was	be	VBD
cord-345879-nbfg47x5	39	15	significantly	significantly	RB
cord-345879-nbfg47x5	39	16	decreased	decrease	VBN
cord-345879-nbfg47x5	39	17	by	by	IN
cord-345879-nbfg47x5	39	18	vagus	vagus	JJ
cord-345879-nbfg47x5	39	19	nerve	nerve	NN
cord-345879-nbfg47x5	39	20	stimulation	stimulation	NN
cord-345879-nbfg47x5	39	21	(	(	-LRB-
cord-345879-nbfg47x5	39	22	VNS	VNS	NNP
cord-345879-nbfg47x5	39	23	)	)	-RRB-
cord-345879-nbfg47x5	39	24	but	but	CC
cord-345879-nbfg47x5	39	25	not	not	RB
cord-345879-nbfg47x5	39	26	the	the	DT
cord-345879-nbfg47x5	39	27	anti	anti	JJ
cord-345879-nbfg47x5	39	28	-	-	JJ
cord-345879-nbfg47x5	39	29	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	39	30	cytokine	cytokine	NN
cord-345879-nbfg47x5	39	31	IL-10	IL-10	NNP
cord-345879-nbfg47x5	39	32	.	.	.
cord-345879-nbfg47x5	40	1	Consequently	consequently	RB
cord-345879-nbfg47x5	40	2	,	,	,
cord-345879-nbfg47x5	40	3	we	-PRON-	PRP
cord-345879-nbfg47x5	40	4	hypothesize	hypothesize	VBP
cord-345879-nbfg47x5	40	5	that	that	IN
cord-345879-nbfg47x5	40	6	targeting	target	VBG
cord-345879-nbfg47x5	40	7	the	the	DT
cord-345879-nbfg47x5	40	8	CAP	cap	NN
cord-345879-nbfg47x5	40	9	with	with	IN
cord-345879-nbfg47x5	40	10	VNS	VNS	NNP
cord-345879-nbfg47x5	40	11	could	could	MD
cord-345879-nbfg47x5	40	12	be	be	VB
cord-345879-nbfg47x5	40	13	of	of	IN
cord-345879-nbfg47x5	40	14	interest	interest	NN
cord-345879-nbfg47x5	40	15	in	in	IN
cord-345879-nbfg47x5	40	16	patients	patient	NNS
cord-345879-nbfg47x5	40	17	with	with	IN
cord-345879-nbfg47x5	40	18	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	40	19	.	.	.
cord-345879-nbfg47x5	41	1	To	to	TO
cord-345879-nbfg47x5	41	2	reinforce	reinforce	VB
cord-345879-nbfg47x5	41	3	this	this	DT
cord-345879-nbfg47x5	41	4	hypothesis	hypothesis	NN
cord-345879-nbfg47x5	41	5	,	,	,
cord-345879-nbfg47x5	41	6	Staats	Staats	NNP
cord-345879-nbfg47x5	41	7	et	et	NNP
cord-345879-nbfg47x5	41	8	al	al	NNP
cord-345879-nbfg47x5	41	9	.	.	.
cord-345879-nbfg47x5	42	1	(	(	-LRB-
cord-345879-nbfg47x5	42	2	Staats	Staats	NNP
cord-345879-nbfg47x5	42	3	et	et	NNP
cord-345879-nbfg47x5	42	4	al	al	NNP
cord-345879-nbfg47x5	42	5	.	.	NNP
cord-345879-nbfg47x5	42	6	2020	2020	CD
cord-345879-nbfg47x5	42	7	)	)	-RRB-
cord-345879-nbfg47x5	42	8	have	have	VBP
cord-345879-nbfg47x5	42	9	recently	recently	RB
cord-345879-nbfg47x5	42	10	reported	report	VBN
cord-345879-nbfg47x5	42	11	the	the	DT
cord-345879-nbfg47x5	42	12	clinical	clinical	JJ
cord-345879-nbfg47x5	42	13	benefit	benefit	NN
cord-345879-nbfg47x5	42	14	of	of	IN
cord-345879-nbfg47x5	42	15	VNS	VNS	NNP
cord-345879-nbfg47x5	42	16	in	in	IN
cord-345879-nbfg47x5	42	17	two	two	CD
cord-345879-nbfg47x5	42	18	patients	patient	NNS
cord-345879-nbfg47x5	42	19	with	with	IN
cord-345879-nbfg47x5	42	20	respiratory	respiratory	JJ
cord-345879-nbfg47x5	42	21	symptoms	symptom	NNS
cord-345879-nbfg47x5	42	22	similar	similar	JJ
cord-345879-nbfg47x5	42	23	to	to	IN
cord-345879-nbfg47x5	42	24	those	those	DT
cord-345879-nbfg47x5	42	25	associated	associate	VBN
cord-345879-nbfg47x5	42	26	with	with	IN
cord-345879-nbfg47x5	42	27	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	42	28	but	but	CC
cord-345879-nbfg47x5	42	29	these	these	DT
cord-345879-nbfg47x5	42	30	preliminary	preliminary	JJ
cord-345879-nbfg47x5	42	31	results	result	NNS
cord-345879-nbfg47x5	42	32	need	need	VBP
cord-345879-nbfg47x5	42	33	to	to	TO
cord-345879-nbfg47x5	42	34	be	be	VB
cord-345879-nbfg47x5	42	35	confirmed	confirm	VBN
cord-345879-nbfg47x5	42	36	in	in	IN
cord-345879-nbfg47x5	42	37	a	a	DT
cord-345879-nbfg47x5	42	38	larger	large	JJR
cord-345879-nbfg47x5	42	39	randomized	randomized	JJ
cord-345879-nbfg47x5	42	40	doubleblinded	doubleblinded	JJ
cord-345879-nbfg47x5	42	41	control	control	NNP
cord-345879-nbfg47x5	42	42	study	study	NN
cord-345879-nbfg47x5	42	43	.	.	.
cord-345879-nbfg47x5	43	1	The	the	DT
cord-345879-nbfg47x5	43	2	vagus	vagus	NN
cord-345879-nbfg47x5	43	3	nerve	nerve	NN
cord-345879-nbfg47x5	43	4	,	,	,
cord-345879-nbfg47x5	43	5	the	the	DT
cord-345879-nbfg47x5	43	6	longest	long	JJS
cord-345879-nbfg47x5	43	7	nerve	nerve	NN
cord-345879-nbfg47x5	43	8	of	of	IN
cord-345879-nbfg47x5	43	9	the	the	DT
cord-345879-nbfg47x5	43	10	organism	organism	NN
cord-345879-nbfg47x5	43	11	,	,	,
cord-345879-nbfg47x5	43	12	innervates	innervate	VBZ
cord-345879-nbfg47x5	43	13	the	the	DT
cord-345879-nbfg47x5	43	14	lungs	lung	NNS
cord-345879-nbfg47x5	43	15	and	and	CC
cord-345879-nbfg47x5	43	16	the	the	DT
cord-345879-nbfg47x5	43	17	gastrointestinal	gastrointestinal	JJ
cord-345879-nbfg47x5	43	18	(	(	-LRB-
cord-345879-nbfg47x5	43	19	GI	GI	NNP
cord-345879-nbfg47x5	43	20	)	)	-RRB-
cord-345879-nbfg47x5	43	21	tract	tract	NN
cord-345879-nbfg47x5	43	22	,	,	,
cord-345879-nbfg47x5	43	23	two	two	CD
cord-345879-nbfg47x5	43	24	organs	organ	NNS
cord-345879-nbfg47x5	43	25	which	which	WDT
cord-345879-nbfg47x5	43	26	are	be	VBP
cord-345879-nbfg47x5	43	27	targeted	target	VBN
cord-345879-nbfg47x5	43	28	by	by	IN
cord-345879-nbfg47x5	43	29	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	43	30	.	.	.
cord-345879-nbfg47x5	43	31	ACh	ACh	NNP
cord-345879-nbfg47x5	43	32	released	release	VBD
cord-345879-nbfg47x5	43	33	at	at	IN
cord-345879-nbfg47x5	43	34	the	the	DT
cord-345879-nbfg47x5	43	35	distal	distal	JJ
cord-345879-nbfg47x5	43	36	end	end	NN
cord-345879-nbfg47x5	43	37	of	of	IN
cord-345879-nbfg47x5	43	38	the	the	DT
cord-345879-nbfg47x5	43	39	vagus	vagus	NN
cord-345879-nbfg47x5	43	40	nerve	nerve	NN
cord-345879-nbfg47x5	43	41	acts	act	VBZ
cord-345879-nbfg47x5	43	42	on	on	IN
cord-345879-nbfg47x5	43	43	intrinsic	intrinsic	JJ
cord-345879-nbfg47x5	43	44	neurons	neuron	NNS
cord-345879-nbfg47x5	43	45	of	of	IN
cord-345879-nbfg47x5	43	46	the	the	DT
cord-345879-nbfg47x5	43	47	enteric	enteric	JJ
cord-345879-nbfg47x5	43	48	nervous	nervous	JJ
cord-345879-nbfg47x5	43	49	system	system	NN
cord-345879-nbfg47x5	43	50	e.g.	e.g.	RB
cord-345879-nbfg47x5	43	51	at	at	IN
cord-345879-nbfg47x5	43	52	the	the	DT
cord-345879-nbfg47x5	43	53	level	level	NN
cord-345879-nbfg47x5	43	54	of	of	IN
cord-345879-nbfg47x5	43	55	the	the	DT
cord-345879-nbfg47x5	43	56	GI	GI	NNP
cord-345879-nbfg47x5	43	57	tract	tract	NN
cord-345879-nbfg47x5	43	58	to	to	TO
cord-345879-nbfg47x5	43	59	inhibit	inhibit	VB
cord-345879-nbfg47x5	43	60	the	the	DT
cord-345879-nbfg47x5	43	61	release	release	NN
cord-345879-nbfg47x5	43	62	of	of	IN
cord-345879-nbfg47x5	43	63	TNF	TNF	NNP
cord-345879-nbfg47x5	43	64	by	by	IN
cord-345879-nbfg47x5	43	65	macrophages	macrophage	NNS
cord-345879-nbfg47x5	43	66	(	(	-LRB-
cord-345879-nbfg47x5	43	67	Matteoli	Matteoli	NNP
cord-345879-nbfg47x5	43	68	et	et	NNP
cord-345879-nbfg47x5	43	69	al	al	NNP
cord-345879-nbfg47x5	43	70	.	.	NNP
cord-345879-nbfg47x5	43	71	2014	2014	CD
cord-345879-nbfg47x5	43	72	)	)	-RRB-
cord-345879-nbfg47x5	44	1	(	(	-LRB-
cord-345879-nbfg47x5	44	2	Fig	Fig	NNP
cord-345879-nbfg47x5	44	3	.	.	NNP
cord-345879-nbfg47x5	44	4	1	1	CD
cord-345879-nbfg47x5	44	5	)	)	-RRB-
cord-345879-nbfg47x5	44	6	.	.	.
cord-345879-nbfg47x5	45	1	A	a	DT
cord-345879-nbfg47x5	45	2	vagosplenic	vagosplenic	NN
cord-345879-nbfg47x5	45	3	pathway	pathway	NN
cord-345879-nbfg47x5	45	4	inhibiting	inhibit	VBG
cord-345879-nbfg47x5	45	5	the	the	DT
cord-345879-nbfg47x5	45	6	release	release	NN
cord-345879-nbfg47x5	45	7	of	of	IN
cord-345879-nbfg47x5	45	8	TNF	TNF	NNP
cord-345879-nbfg47x5	45	9	by	by	IN
cord-345879-nbfg47x5	45	10	splenic	splenic	JJ
cord-345879-nbfg47x5	45	11	macrophages	macrophage	NNS
cord-345879-nbfg47x5	45	12	has	have	VBZ
cord-345879-nbfg47x5	45	13	also	also	RB
cord-345879-nbfg47x5	45	14	been	be	VBN
cord-345879-nbfg47x5	45	15	described	describe	VBN
cord-345879-nbfg47x5	45	16	by	by	IN
cord-345879-nbfg47x5	45	17	the	the	DT
cord-345879-nbfg47x5	45	18	Tracey	Tracey	NNP
cord-345879-nbfg47x5	45	19	group	group	NN
cord-345879-nbfg47x5	45	20	(	(	-LRB-
cord-345879-nbfg47x5	45	21	Fig	Fig	NNP
cord-345879-nbfg47x5	45	22	.	.	.
cord-345879-nbfg47x5	45	23	1	1	CD
cord-345879-nbfg47x5	45	24	)	)	-RRB-
cord-345879-nbfg47x5	45	25	.	.	.
cord-345879-nbfg47x5	46	1	This	this	DT
cord-345879-nbfg47x5	46	2	effect	effect	NN
cord-345879-nbfg47x5	46	3	is	be	VBZ
cord-345879-nbfg47x5	46	4	mediated	mediate	VBN
cord-345879-nbfg47x5	46	5	through	through	IN
cord-345879-nbfg47x5	46	6	the	the	DT
cord-345879-nbfg47x5	46	7	link	link	NN
cord-345879-nbfg47x5	46	8	of	of	IN
cord-345879-nbfg47x5	46	9	norepinephrine	norepinephrine	NN
cord-345879-nbfg47x5	46	10	on	on	IN
cord-345879-nbfg47x5	46	11	β2-adrenergic	β2-adrenergic	JJ
cord-345879-nbfg47x5	46	12	receptors	receptor	NNS
cord-345879-nbfg47x5	46	13	of	of	IN
cord-345879-nbfg47x5	46	14	splenic	splenic	JJ
cord-345879-nbfg47x5	46	15	CD4	CD4	NNP
cord-345879-nbfg47x5	46	16	+	+	CC
cord-345879-nbfg47x5	46	17	T	t	NN
cord-345879-nbfg47x5	46	18	cells	cell	NNS
cord-345879-nbfg47x5	46	19	that	that	WDT
cord-345879-nbfg47x5	46	20	release	release	VBP
cord-345879-nbfg47x5	46	21	ACh	ACh	NNP
cord-345879-nbfg47x5	46	22	acting	act	VBG
cord-345879-nbfg47x5	46	23	on	on	IN
cord-345879-nbfg47x5	46	24	α7nAChRs	α7nachr	NNS
cord-345879-nbfg47x5	46	25	of	of	IN
cord-345879-nbfg47x5	46	26	splenic	splenic	JJ
cord-345879-nbfg47x5	46	27	macrophages	macrophage	NNS
cord-345879-nbfg47x5	46	28	(	(	-LRB-
cord-345879-nbfg47x5	46	29	Rosas	Rosas	NNP
cord-345879-nbfg47x5	46	30	-	-	HYPH
cord-345879-nbfg47x5	46	31	Ballina	Ballina	NNP
cord-345879-nbfg47x5	46	32	et	et	NNP
cord-345879-nbfg47x5	46	33	al	al	NNP
cord-345879-nbfg47x5	46	34	.	.	NNP
cord-345879-nbfg47x5	46	35	2008	2008	CD
cord-345879-nbfg47x5	46	36	)	)	-RRB-
cord-345879-nbfg47x5	46	37	i.e.	i.e.	FW
cord-345879-nbfg47x5	46	38	the	the	DT
cord-345879-nbfg47x5	46	39	non	non	JJ
cord-345879-nbfg47x5	46	40	-	-	JJ
cord-345879-nbfg47x5	46	41	neuronal	neuronal	JJ
cord-345879-nbfg47x5	46	42	cholinergic	cholinergic	JJ
cord-345879-nbfg47x5	46	43	pathway	pathway	NN
cord-345879-nbfg47x5	46	44	.	.	.
cord-345879-nbfg47x5	47	1	The	the	DT
cord-345879-nbfg47x5	47	2	intra	intra	JJ
cord-345879-nbfg47x5	47	3	-	-	JJ
cord-345879-nbfg47x5	47	4	cellular	cellular	JJ
cord-345879-nbfg47x5	47	5	signaling	signaling	NN
cord-345879-nbfg47x5	47	6	of	of	IN
cord-345879-nbfg47x5	47	7	α7nAChRs	α7nachr	NNS
cord-345879-nbfg47x5	47	8	inhibits	inhibit	VBZ
cord-345879-nbfg47x5	47	9	transactivational	transactivational	JJ
cord-345879-nbfg47x5	47	10	activity	activity	NN
cord-345879-nbfg47x5	47	11	of	of	IN
cord-345879-nbfg47x5	47	12	the	the	DT
cord-345879-nbfg47x5	47	13	transcription	transcription	NN
cord-345879-nbfg47x5	47	14	factor	factor	NN
cord-345879-nbfg47x5	47	15	NF	NF	NNP
cord-345879-nbfg47x5	47	16	-	-	HYPH
cord-345879-nbfg47x5	47	17	kB	kB	NNP
cord-345879-nbfg47x5	47	18	p65	p65	NN
cord-345879-nbfg47x5	47	19	(	(	-LRB-
cord-345879-nbfg47x5	47	20	Wang	Wang	NNP
cord-345879-nbfg47x5	47	21	et	et	NNP
cord-345879-nbfg47x5	47	22	al	al	NNP
cord-345879-nbfg47x5	47	23	.	.	.
cord-345879-nbfg47x5	47	24	2004	2004	CD
cord-345879-nbfg47x5	47	25	)	)	-RRB-
cord-345879-nbfg47x5	47	26	and	and	CC
cord-345879-nbfg47x5	47	27	activates	activate	VBZ
cord-345879-nbfg47x5	47	28	Jak2	Jak2	NNP
cord-345879-nbfg47x5	47	29	and	and	CC
cord-345879-nbfg47x5	47	30	STAT3	STAT3	NNP
cord-345879-nbfg47x5	47	31	signaling	signal	VBG
cord-345879-nbfg47x5	47	32	(	(	-LRB-
cord-345879-nbfg47x5	47	33	de	de	FW
cord-345879-nbfg47x5	47	34	Jonge	Jonge	NNP
cord-345879-nbfg47x5	47	35	et	et	NNP
cord-345879-nbfg47x5	47	36	al	al	NNP
cord-345879-nbfg47x5	47	37	.	.	NNP
cord-345879-nbfg47x5	47	38	2005	2005	CD
cord-345879-nbfg47x5	47	39	)	)	-RRB-
cord-345879-nbfg47x5	47	40	.	.	.
cord-345879-nbfg47x5	48	1	Thus	thus	RB
cord-345879-nbfg47x5	48	2	,	,	,
cord-345879-nbfg47x5	48	3	targeting	target	VBG
cord-345879-nbfg47x5	48	4	α7nAChRs	α7nachrs	XX
cord-345879-nbfg47x5	48	5	with	with	IN
cord-345879-nbfg47x5	48	6	VNS	VNS	NNP
cord-345879-nbfg47x5	48	7	should	should	MD
cord-345879-nbfg47x5	48	8	be	be	VB
cord-345879-nbfg47x5	48	9	of	of	IN
cord-345879-nbfg47x5	48	10	interest	interest	NN
cord-345879-nbfg47x5	48	11	in	in	IN
cord-345879-nbfg47x5	48	12	the	the	DT
cord-345879-nbfg47x5	48	13	management	management	NN
cord-345879-nbfg47x5	48	14	of	of	IN
cord-345879-nbfg47x5	48	15	patients	patient	NNS
cord-345879-nbfg47x5	48	16	with	with	IN
cord-345879-nbfg47x5	48	17	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	48	18	.	.	.
cord-345879-nbfg47x5	49	1	The	the	DT
cord-345879-nbfg47x5	49	2	detrimental	detrimental	JJ
cord-345879-nbfg47x5	49	3	effect	effect	NN
cord-345879-nbfg47x5	49	4	of	of	IN
cord-345879-nbfg47x5	49	5	smoking	smoking	NN
cord-345879-nbfg47x5	49	6	on	on	IN
cord-345879-nbfg47x5	49	7	cardiovascular	cardiovascular	JJ
cord-345879-nbfg47x5	49	8	and	and	CC
cord-345879-nbfg47x5	49	9	pulmonary	pulmonary	JJ
cord-345879-nbfg47x5	49	10	disease	disease	NN
cord-345879-nbfg47x5	49	11	has	have	VBZ
cord-345879-nbfg47x5	49	12	long	long	RB
cord-345879-nbfg47x5	49	13	been	be	VBN
cord-345879-nbfg47x5	49	14	recognised	recognise	VBN
cord-345879-nbfg47x5	49	15	.	.	.
cord-345879-nbfg47x5	50	1	Thus	thus	RB
cord-345879-nbfg47x5	50	2	,	,	,
cord-345879-nbfg47x5	50	3	smoking	smoking	NN
cord-345879-nbfg47x5	50	4	should	should	MD
cord-345879-nbfg47x5	50	5	be	be	VB
cord-345879-nbfg47x5	50	6	an	an	DT
cord-345879-nbfg47x5	50	7	aggravating	aggravating	JJ
cord-345879-nbfg47x5	50	8	factor	factor	NN
cord-345879-nbfg47x5	50	9	of	of	IN
cord-345879-nbfg47x5	50	10	COVID-19	covid-19	JJ
cord-345879-nbfg47x5	50	11	infection	infection	NN
cord-345879-nbfg47x5	50	12	.	.	.
cord-345879-nbfg47x5	51	1	However	however	RB
cord-345879-nbfg47x5	51	2	,	,	,
cord-345879-nbfg47x5	51	3	data	datum	NNS
cord-345879-nbfg47x5	51	4	are	be	VBP
cord-345879-nbfg47x5	51	5	contradictory	contradictory	JJ
cord-345879-nbfg47x5	51	6	since	since	IN
cord-345879-nbfg47x5	51	7	if	if	IN
cord-345879-nbfg47x5	51	8	for	for	IN
cord-345879-nbfg47x5	51	9	some	some	DT
cord-345879-nbfg47x5	51	10	,	,	,
cord-345879-nbfg47x5	51	11	smoking	smoking	NN
cord-345879-nbfg47x5	51	12	is	be	VBZ
cord-345879-nbfg47x5	51	13	associated	associate	VBN
cord-345879-nbfg47x5	51	14	with	with	IN
cord-345879-nbfg47x5	51	15	a	a	DT
cord-345879-nbfg47x5	51	16	negative	negative	JJ
cord-345879-nbfg47x5	51	17	progression	progression	NN
cord-345879-nbfg47x5	51	18	and	and	CC
cord-345879-nbfg47x5	51	19	adverse	adverse	JJ
cord-345879-nbfg47x5	51	20	outcomes	outcome	NNS
cord-345879-nbfg47x5	52	1	(	(	-LRB-
cord-345879-nbfg47x5	52	2	Alqahtani	Alqahtani	NNP
cord-345879-nbfg47x5	52	3	et	et	NNP
cord-345879-nbfg47x5	52	4	al	al	NNP
cord-345879-nbfg47x5	52	5	.	.	NNP
cord-345879-nbfg47x5	52	6	2020	2020	CD
cord-345879-nbfg47x5	52	7	)	)	-RRB-
cord-345879-nbfg47x5	52	8	,	,	,
cord-345879-nbfg47x5	52	9	for	for	IN
cord-345879-nbfg47x5	52	10	others	other	NNS
cord-345879-nbfg47x5	52	11	it	-PRON-	PRP
cord-345879-nbfg47x5	52	12	has	have	VBZ
cord-345879-nbfg47x5	52	13	a	a	DT
cord-345879-nbfg47x5	52	14	protective	protective	JJ
cord-345879-nbfg47x5	52	15	role	role	NN
cord-345879-nbfg47x5	52	16	(	(	-LRB-
cord-345879-nbfg47x5	52	17	Farsalinos	Farsalinos	NNP
cord-345879-nbfg47x5	52	18	et	et	NNP
cord-345879-nbfg47x5	52	19	al	al	NNP
cord-345879-nbfg47x5	52	20	.	.	NNP
cord-345879-nbfg47x5	52	21	2020a	2020a	CD
cord-345879-nbfg47x5	52	22	)	)	-RRB-
cord-345879-nbfg47x5	52	23	.	.	.
cord-345879-nbfg47x5	53	1	The	the	DT
cord-345879-nbfg47x5	53	2	protective	protective	JJ
cord-345879-nbfg47x5	53	3	effect	effect	NN
cord-345879-nbfg47x5	53	4	of	of	IN
cord-345879-nbfg47x5	53	5	smoking	smoking	NN
cord-345879-nbfg47x5	53	6	is	be	VBZ
cord-345879-nbfg47x5	53	7	well	well	RB
cord-345879-nbfg47x5	53	8	known	know	VBN
cord-345879-nbfg47x5	53	9	in	in	IN
cord-345879-nbfg47x5	53	10	ulcerative	ulcerative	JJ
cord-345879-nbfg47x5	53	11	colitis	colitis	NN
cord-345879-nbfg47x5	53	12	,	,	,
cord-345879-nbfg47x5	53	13	a	a	DT
cord-345879-nbfg47x5	53	14	chronic	chronic	JJ
cord-345879-nbfg47x5	53	15	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	53	16	bowel	bowel	NN
cord-345879-nbfg47x5	53	17	disease	disease	NN
cord-345879-nbfg47x5	53	18	(	(	-LRB-
cord-345879-nbfg47x5	53	19	IBD	IBD	NNP
cord-345879-nbfg47x5	53	20	)	)	-RRB-
cord-345879-nbfg47x5	54	1	(	(	-LRB-
cord-345879-nbfg47x5	54	2	Berkowitz	Berkowitz	NNP
cord-345879-nbfg47x5	54	3	et	et	NNP
cord-345879-nbfg47x5	54	4	al	al	NNP
cord-345879-nbfg47x5	54	5	.	.	.
cord-345879-nbfg47x5	54	6	2018	2018	CD
cord-345879-nbfg47x5	54	7	)	)	-RRB-
cord-345879-nbfg47x5	54	8	.	.	.
cord-345879-nbfg47x5	55	1	Recently	recently	RB
cord-345879-nbfg47x5	55	2	,	,	,
cord-345879-nbfg47x5	55	3	Miyara	Miyara	NNP
cord-345879-nbfg47x5	55	4	et	et	NNP
cord-345879-nbfg47x5	55	5	al	al	NNP
cord-345879-nbfg47x5	55	6	.	.	.
cord-345879-nbfg47x5	55	7	)	)	-RRB-
cord-345879-nbfg47x5	55	8	looked	look	VBD
cord-345879-nbfg47x5	55	9	more	more	RBR
cord-345879-nbfg47x5	55	10	closely	closely	RB
cord-345879-nbfg47x5	55	11	at	at	IN
cord-345879-nbfg47x5	55	12	482	482	CD
cord-345879-nbfg47x5	55	13	patients	patient	NNS
cord-345879-nbfg47x5	55	14	positive	positive	JJ
cord-345879-nbfg47x5	55	15	for	for	IN
cord-345879-nbfg47x5	55	16	COVID-19	covid-19	NN
cord-345879-nbfg47x5	55	17	at	at	IN
cord-345879-nbfg47x5	55	18	the	the	DT
cord-345879-nbfg47x5	55	19	Pitié	Pitié	NNP
cord-345879-nbfg47x5	55	20	-	-	HYPH
cord-345879-nbfg47x5	55	21	Salpêtrière	Salpêtrière	NNP
cord-345879-nbfg47x5	55	22	hospital	hospital	NN
cord-345879-nbfg47x5	55	23	in	in	IN
cord-345879-nbfg47x5	55	24	Paris	Paris	NNP
cord-345879-nbfg47x5	55	25	and	and	CC
cord-345879-nbfg47x5	55	26	found	find	VBD
cord-345879-nbfg47x5	55	27	that	that	IN
cord-345879-nbfg47x5	55	28	among	among	IN
cord-345879-nbfg47x5	55	29	the	the	DT
cord-345879-nbfg47x5	55	30	343	343	CD
cord-345879-nbfg47x5	55	31	patients	patient	NNS
cord-345879-nbfg47x5	55	32	hospitalised	hospitalise	VBN
cord-345879-nbfg47x5	55	33	for	for	IN
cord-345879-nbfg47x5	55	34	serious	serious	JJ
cord-345879-nbfg47x5	55	35	complications	complication	NNS
cord-345879-nbfg47x5	55	36	and	and	CC
cord-345879-nbfg47x5	55	37	the	the	DT
cord-345879-nbfg47x5	55	38	139	139	CD
cord-345879-nbfg47x5	55	39	patients	patient	NNS
cord-345879-nbfg47x5	55	40	who	who	WP
cord-345879-nbfg47x5	55	41	were	be	VBD
cord-345879-nbfg47x5	55	42	sent	send	VBN
cord-345879-nbfg47x5	55	43	home	home	RB
cord-345879-nbfg47x5	55	44	,	,	,
cord-345879-nbfg47x5	55	45	4.4	4.4	CD
cord-345879-nbfg47x5	55	46	and	and	CC
cord-345879-nbfg47x5	55	47	5.3	5.3	CD
cord-345879-nbfg47x5	55	48	%	%	NN
cord-345879-nbfg47x5	55	49	were	be	VBD
cord-345879-nbfg47x5	55	50	daily	daily	JJ
cord-345879-nbfg47x5	55	51	smokers	smoker	NNS
cord-345879-nbfg47x5	55	52	respectively	respectively	RB
cord-345879-nbfg47x5	55	53	while	while	IN
cord-345879-nbfg47x5	55	54	the	the	DT
cord-345879-nbfg47x5	55	55	rate	rate	NN
cord-345879-nbfg47x5	55	56	of	of	IN
cord-345879-nbfg47x5	55	57	daily	daily	JJ
cord-345879-nbfg47x5	55	58	smokers	smoker	NNS
cord-345879-nbfg47x5	55	59	is	be	VBZ
cord-345879-nbfg47x5	55	60	25.4	25.4	CD
cord-345879-nbfg47x5	55	61	%	%	NN
cord-345879-nbfg47x5	55	62	in	in	IN
cord-345879-nbfg47x5	55	63	the	the	DT
cord-345879-nbfg47x5	55	64	country	country	NN
cord-345879-nbfg47x5	55	65	.	.	.
cord-345879-nbfg47x5	56	1	They	-PRON-	PRP
cord-345879-nbfg47x5	56	2	suggest	suggest	VBP
cord-345879-nbfg47x5	56	3	that	that	IN
cord-345879-nbfg47x5	56	4	smoking	smoking	NN
cord-345879-nbfg47x5	56	5	protection	protection	NN
cord-345879-nbfg47x5	56	6	is	be	VBZ
cord-345879-nbfg47x5	56	7	likely	likely	RB
cord-345879-nbfg47x5	56	8	mediated	mediate	VBN
cord-345879-nbfg47x5	56	9	by	by	IN
cord-345879-nbfg47x5	56	10	nicotine	nicotine	NN
cord-345879-nbfg47x5	56	11	,	,	,
cord-345879-nbfg47x5	56	12	which	which	WDT
cord-345879-nbfg47x5	56	13	alters	alter	VBZ
cord-345879-nbfg47x5	56	14	the	the	DT
cord-345879-nbfg47x5	56	15	homeostasis	homeostasis	NN
cord-345879-nbfg47x5	56	16	of	of	IN
cord-345879-nbfg47x5	56	17	the	the	DT
cord-345879-nbfg47x5	56	18	reninangiotensin	reninangiotensin	NNP
cord-345879-nbfg47x5	56	19	system	system	NN
cord-345879-nbfg47x5	56	20	.	.	.
cord-345879-nbfg47x5	57	1	They	-PRON-	PRP
cord-345879-nbfg47x5	57	2	conclude	conclude	VBP
cord-345879-nbfg47x5	57	3	that	that	IN
cord-345879-nbfg47x5	57	4	nicotine	nicotine	NN
cord-345879-nbfg47x5	57	5	administration	administration	NN
cord-345879-nbfg47x5	57	6	may	may	MD
cord-345879-nbfg47x5	57	7	be	be	VB
cord-345879-nbfg47x5	57	8	tested	test	VBN
cord-345879-nbfg47x5	57	9	as	as	IN
cord-345879-nbfg47x5	57	10	a	a	DT
cord-345879-nbfg47x5	57	11	therapy	therapy	NN
cord-345879-nbfg47x5	57	12	to	to	TO
cord-345879-nbfg47x5	57	13	recapitulate	recapitulate	VB
cord-345879-nbfg47x5	57	14	the	the	DT
cord-345879-nbfg47x5	57	15	protecting	protect	VBG
cord-345879-nbfg47x5	57	16	effect	effect	NN
cord-345879-nbfg47x5	57	17	of	of	IN
cord-345879-nbfg47x5	57	18	smoking	smoking	NN
cord-345879-nbfg47x5	57	19	against	against	IN
cord-345879-nbfg47x5	57	20	SARS	SARS	NNP
cord-345879-nbfg47x5	57	21	-	-	HYPH
cord-345879-nbfg47x5	57	22	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	57	23	infection	infection	NN
cord-345879-nbfg47x5	57	24	.	.	.
cord-345879-nbfg47x5	58	1	Obviously	obviously	RB
cord-345879-nbfg47x5	58	2	,	,	,
cord-345879-nbfg47x5	58	3	smoking	smoking	NN
cord-345879-nbfg47x5	58	4	can	can	MD
cord-345879-nbfg47x5	58	5	not	not	RB
cord-345879-nbfg47x5	58	6	be	be	VB
cord-345879-nbfg47x5	58	7	recommended	recommend	VBN
cord-345879-nbfg47x5	58	8	as	as	IN
cord-345879-nbfg47x5	58	9	a	a	DT
cord-345879-nbfg47x5	58	10	way	way	NN
cord-345879-nbfg47x5	58	11	of	of	IN
cord-345879-nbfg47x5	58	12	protecting	protect	VBG
cord-345879-nbfg47x5	58	13	oneself	oneself	PRP
cord-345879-nbfg47x5	58	14	against	against	IN
cord-345879-nbfg47x5	58	15	the	the	DT
cord-345879-nbfg47x5	58	16	new	new	JJ
cord-345879-nbfg47x5	58	17	coronavirus	coronavirus	NN
cord-345879-nbfg47x5	58	18	.	.	.
cord-345879-nbfg47x5	59	1	An	an	DT
cord-345879-nbfg47x5	59	2	increased	increase	VBN
cord-345879-nbfg47x5	59	3	ACE2	ACE2	NNP
cord-345879-nbfg47x5	59	4	expression	expression	NN
cord-345879-nbfg47x5	59	5	in	in	IN
cord-345879-nbfg47x5	59	6	airways	airway	NNS
cord-345879-nbfg47x5	59	7	of	of	IN
cord-345879-nbfg47x5	59	8	current	current	JJ
cord-345879-nbfg47x5	59	9	smokers	smoker	NNS
cord-345879-nbfg47x5	59	10	has	have	VBZ
cord-345879-nbfg47x5	59	11	been	be	VBN
cord-345879-nbfg47x5	59	12	recently	recently	RB
cord-345879-nbfg47x5	59	13	described	describe	VBN
cord-345879-nbfg47x5	59	14	by	by	IN
cord-345879-nbfg47x5	59	15	Leung	Leung	NNP
cord-345879-nbfg47x5	59	16	et	et	NNP
cord-345879-nbfg47x5	59	17	al	al	NNP
cord-345879-nbfg47x5	59	18	.	.	.
cord-345879-nbfg47x5	60	1	(	(	-LRB-
cord-345879-nbfg47x5	60	2	Leung	Leung	NNP
cord-345879-nbfg47x5	60	3	et	et	NNP
cord-345879-nbfg47x5	60	4	al	al	NNP
cord-345879-nbfg47x5	60	5	.	.	NNP
cord-345879-nbfg47x5	60	6	2020	2020	CD
cord-345879-nbfg47x5	60	7	)	)	-RRB-
cord-345879-nbfg47x5	60	8	and	and	CC
cord-345879-nbfg47x5	60	9	Russo	Russo	NNP
cord-345879-nbfg47x5	60	10	et	et	FW
cord-345879-nbfg47x5	60	11	al	al	NNP
cord-345879-nbfg47x5	60	12	.	.	.
cord-345879-nbfg47x5	61	1	(	(	-LRB-
cord-345879-nbfg47x5	61	2	Russo	Russo	NNP
cord-345879-nbfg47x5	61	3	et	et	FW
cord-345879-nbfg47x5	61	4	al	al	NNP
cord-345879-nbfg47x5	61	5	.	.	NNP
cord-345879-nbfg47x5	61	6	2020	2020	CD
cord-345879-nbfg47x5	61	7	)	)	-RRB-
cord-345879-nbfg47x5	61	8	with	with	IN
cord-345879-nbfg47x5	61	9	important	important	JJ
cord-345879-nbfg47x5	61	10	implications	implication	NNS
cord-345879-nbfg47x5	61	11	for	for	IN
cord-345879-nbfg47x5	61	12	COVID-19	covid-19	JJ
cord-345879-nbfg47x5	61	13	patients	patient	NNS
cord-345879-nbfg47x5	61	14	.	.	.
cord-345879-nbfg47x5	62	1	These	these	DT
cord-345879-nbfg47x5	62	2	authors	author	NNS
cord-345879-nbfg47x5	62	3	showed	show	VBD
cord-345879-nbfg47x5	62	4	that	that	IN
cord-345879-nbfg47x5	62	5	nicotine	nicotine	NN
cord-345879-nbfg47x5	62	6	upregulates	upregulate	VBZ
cord-345879-nbfg47x5	62	7	ACE2	ACE2	NNP
cord-345879-nbfg47x5	62	8	through	through	IN
cord-345879-nbfg47x5	62	9	α7nAChRs	α7nachrs	XX
cord-345879-nbfg47x5	62	10	which	which	WDT
cord-345879-nbfg47x5	62	11	are	be	VBP
cord-345879-nbfg47x5	62	12	present	present	JJ
cord-345879-nbfg47x5	62	13	in	in	IN
cord-345879-nbfg47x5	62	14	neuronal	neuronal	JJ
cord-345879-nbfg47x5	62	15	and	and	CC
cord-345879-nbfg47x5	62	16	non	non	JJ
cord-345879-nbfg47x5	62	17	-	-	JJ
cord-345879-nbfg47x5	62	18	neuronal	neuronal	JJ
cord-345879-nbfg47x5	62	19	cells	cell	NNS
cord-345879-nbfg47x5	62	20	.	.	.
cord-345879-nbfg47x5	63	1	There	there	EX
cord-345879-nbfg47x5	63	2	is	be	VBZ
cord-345879-nbfg47x5	63	3	currently	currently	RB
cord-345879-nbfg47x5	63	4	no	no	DT
cord-345879-nbfg47x5	63	5	evidence	evidence	NN
cord-345879-nbfg47x5	63	6	suggesting	suggest	VBG
cord-345879-nbfg47x5	63	7	that	that	IN
cord-345879-nbfg47x5	63	8	up	up	IN
cord-345879-nbfg47x5	63	9	-	-	HYPH
cord-345879-nbfg47x5	63	10	regulation	regulation	NN
cord-345879-nbfg47x5	63	11	of	of	IN
cord-345879-nbfg47x5	63	12	ACE2	ACE2	NNP
cord-345879-nbfg47x5	63	13	is	be	VBZ
cord-345879-nbfg47x5	63	14	associated	associate	VBN
cord-345879-nbfg47x5	63	15	with	with	IN
cord-345879-nbfg47x5	63	16	increased	increase	VBN
cord-345879-nbfg47x5	63	17	COVID-19	covid-19	JJ
cord-345879-nbfg47x5	63	18	susceptibility	susceptibility	NN
cord-345879-nbfg47x5	63	19	or	or	CC
cord-345879-nbfg47x5	63	20	severity	severity	NN
cord-345879-nbfg47x5	63	21	.	.	.
cord-345879-nbfg47x5	64	1	In	in	IN
cord-345879-nbfg47x5	64	2	fact	fact	NN
cord-345879-nbfg47x5	64	3	,	,	,
cord-345879-nbfg47x5	64	4	upregulation	upregulation	NN
cord-345879-nbfg47x5	64	5	of	of	IN
cord-345879-nbfg47x5	64	6	ACE2	ACE2	NNP
cord-345879-nbfg47x5	64	7	appears	appear	VBZ
cord-345879-nbfg47x5	64	8	to	to	TO
cord-345879-nbfg47x5	64	9	be	be	VB
cord-345879-nbfg47x5	64	10	protective	protective	JJ
cord-345879-nbfg47x5	64	11	against	against	IN
cord-345879-nbfg47x5	64	12	tissue	tissue	NN
cord-345879-nbfg47x5	64	13	damage	damage	NN
cord-345879-nbfg47x5	64	14	caused	cause	VBN
cord-345879-nbfg47x5	64	15	by	by	IN
cord-345879-nbfg47x5	64	16	SARS	SARS	NNP
cord-345879-nbfg47x5	64	17	-	-	HYPH
cord-345879-nbfg47x5	64	18	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	64	19	(	(	-LRB-
cord-345879-nbfg47x5	64	20	see	see	VB
cord-345879-nbfg47x5	64	21	for	for	IN
cord-345879-nbfg47x5	64	22	review	review	NN
cord-345879-nbfg47x5	64	23	Farsalinos	Farsalinos	NNP
cord-345879-nbfg47x5	64	24	et	et	NNP
cord-345879-nbfg47x5	64	25	al	al	NNP
cord-345879-nbfg47x5	64	26	.	.	.
cord-345879-nbfg47x5	64	27	)	)	-RRB-
cord-345879-nbfg47x5	65	1	(	(	-LRB-
cord-345879-nbfg47x5	65	2	Farsalinos	Farsalinos	NNP
cord-345879-nbfg47x5	65	3	et	et	NNP
cord-345879-nbfg47x5	65	4	al	al	NNP
cord-345879-nbfg47x5	65	5	.	.	NNP
cord-345879-nbfg47x5	65	6	2020b	2020b	CD
cord-345879-nbfg47x5	65	7	)	)	-RRB-
cord-345879-nbfg47x5	65	8	.	.	.
cord-345879-nbfg47x5	66	1	Indeed	indeed	RB
cord-345879-nbfg47x5	66	2	,	,	,
cord-345879-nbfg47x5	66	3	ACE2	ACE2	NNP
cord-345879-nbfg47x5	66	4	protects	protect	VBZ
cord-345879-nbfg47x5	66	5	mice	mouse	NNS
cord-345879-nbfg47x5	66	6	from	from	IN
cord-345879-nbfg47x5	66	7	developing	develop	VBG
cord-345879-nbfg47x5	66	8	acute	acute	JJ
cord-345879-nbfg47x5	66	9	respiratory	respiratory	JJ
cord-345879-nbfg47x5	66	10	distress	distress	NN
cord-345879-nbfg47x5	66	11	syndrome	syndrome	NN
cord-345879-nbfg47x5	67	1	(	(	-LRB-
cord-345879-nbfg47x5	67	2	Imai	Imai	NNP
cord-345879-nbfg47x5	67	3	et	et	NNP
cord-345879-nbfg47x5	67	4	al	al	NNP
cord-345879-nbfg47x5	67	5	.	.	NNP
cord-345879-nbfg47x5	67	6	2005	2005	CD
cord-345879-nbfg47x5	67	7	)	)	-RRB-
cord-345879-nbfg47x5	67	8	.	.	.
cord-345879-nbfg47x5	68	1	Continuous	continuous	JJ
cord-345879-nbfg47x5	68	2	SARS	SARS	NNP
cord-345879-nbfg47x5	68	3	-	-	HYPH
cord-345879-nbfg47x5	68	4	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	68	5	infection	infection	NN
cord-345879-nbfg47x5	68	6	and	and	CC
cord-345879-nbfg47x5	68	7	replication	replication	NN
cord-345879-nbfg47x5	68	8	induces	induce	VBZ
cord-345879-nbfg47x5	68	9	down	down	JJ
cord-345879-nbfg47x5	68	10	-	-	HYPH
cord-345879-nbfg47x5	68	11	regulation	regulation	NN
cord-345879-nbfg47x5	68	12	of	of	IN
cord-345879-nbfg47x5	68	13	ACE2	ACE2	NNP
cord-345879-nbfg47x5	68	14	,	,	,
cord-345879-nbfg47x5	68	15	which	which	WDT
cord-345879-nbfg47x5	68	16	may	may	MD
cord-345879-nbfg47x5	68	17	be	be	VB
cord-345879-nbfg47x5	68	18	implicated	implicate	VBN
cord-345879-nbfg47x5	68	19	in	in	IN
cord-345879-nbfg47x5	68	20	organ	organ	NN
cord-345879-nbfg47x5	68	21	damage	damage	NN
cord-345879-nbfg47x5	68	22	and	and	CC
cord-345879-nbfg47x5	68	23	disease	disease	NN
cord-345879-nbfg47x5	68	24	severity	severity	NN
cord-345879-nbfg47x5	69	1	(	(	-LRB-
cord-345879-nbfg47x5	69	2	Vaduganathan	Vaduganathan	NNP
cord-345879-nbfg47x5	69	3	et	et	FW
cord-345879-nbfg47x5	69	4	al	al	NNP
cord-345879-nbfg47x5	69	5	.	.	NNP
cord-345879-nbfg47x5	69	6	2020	2020	CD
cord-345879-nbfg47x5	69	7	)	)	-RRB-
cord-345879-nbfg47x5	69	8	.	.	.
cord-345879-nbfg47x5	70	1	Recently	recently	RB
cord-345879-nbfg47x5	70	2	,	,	,
cord-345879-nbfg47x5	70	3	a	a	DT
cord-345879-nbfg47x5	70	4	hypothesis	hypothesis	NN
cord-345879-nbfg47x5	70	5	that	that	IN
cord-345879-nbfg47x5	70	6	the	the	DT
cord-345879-nbfg47x5	70	7	nicotinic	nicotinic	JJ
cord-345879-nbfg47x5	70	8	cholinergic	cholinergic	JJ
cord-345879-nbfg47x5	70	9	system	system	NN
cord-345879-nbfg47x5	70	10	may	may	MD
cord-345879-nbfg47x5	70	11	be	be	VB
cord-345879-nbfg47x5	70	12	involved	involve	VBN
cord-345879-nbfg47x5	70	13	in	in	IN
cord-345879-nbfg47x5	70	14	COVID-19	covid-19	JJ
cord-345879-nbfg47x5	70	15	infection	infection	NN
cord-345879-nbfg47x5	70	16	was	be	VBD
cord-345879-nbfg47x5	70	17	presented	present	VBN
cord-345879-nbfg47x5	70	18	,	,	,
cord-345879-nbfg47x5	70	19	based	base	VBN
cord-345879-nbfg47x5	70	20	on	on	IN
cord-345879-nbfg47x5	70	21	the	the	DT
cord-345879-nbfg47x5	70	22	fact	fact	NN
cord-345879-nbfg47x5	70	23	that	that	IN
cord-345879-nbfg47x5	70	24	several	several	JJ
cord-345879-nbfg47x5	70	25	of	of	IN
cord-345879-nbfg47x5	70	26	the	the	DT
cord-345879-nbfg47x5	70	27	symptoms	symptom	NNS
cord-345879-nbfg47x5	70	28	and	and	CC
cord-345879-nbfg47x5	70	29	clinical	clinical	JJ
cord-345879-nbfg47x5	70	30	signs	sign	NNS
cord-345879-nbfg47x5	70	31	of	of	IN
cord-345879-nbfg47x5	70	32	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	70	33	,	,	,
cord-345879-nbfg47x5	70	34	including	include	VBG
cord-345879-nbfg47x5	70	35	the	the	DT
cord-345879-nbfg47x5	70	36	cytokine	cytokine	NN
cord-345879-nbfg47x5	70	37	storm	storm	NN
cord-345879-nbfg47x5	70	38	,	,	,
cord-345879-nbfg47x5	70	39	could	could	MD
cord-345879-nbfg47x5	70	40	be	be	VB
cord-345879-nbfg47x5	70	41	explained	explain	VBN
cord-345879-nbfg47x5	70	42	by	by	IN
cord-345879-nbfg47x5	70	43	dysfunction	dysfunction	NN
cord-345879-nbfg47x5	70	44	of	of	IN
cord-345879-nbfg47x5	70	45	the	the	DT
cord-345879-nbfg47x5	70	46	CAP	cap	NN
cord-345879-nbfg47x5	70	47	(	(	-LRB-
cord-345879-nbfg47x5	70	48	Farsalinos	Farsalinos	NNP
cord-345879-nbfg47x5	70	49	et	et	NNP
cord-345879-nbfg47x5	70	50	al	al	NNP
cord-345879-nbfg47x5	70	51	.	.	NNP
cord-345879-nbfg47x5	70	52	2020b	2020b	CD
cord-345879-nbfg47x5	70	53	)	)	-RRB-
cord-345879-nbfg47x5	70	54	.	.	.
cord-345879-nbfg47x5	71	1	Dysfunction	dysfunction	NN
cord-345879-nbfg47x5	71	2	of	of	IN
cord-345879-nbfg47x5	71	3	the	the	DT
cord-345879-nbfg47x5	71	4	nicotinic	nicotinic	JJ
cord-345879-nbfg47x5	71	5	cholinergic	cholinergic	JJ
cord-345879-nbfg47x5	71	6	system	system	NN
cord-345879-nbfg47x5	71	7	could	could	MD
cord-345879-nbfg47x5	71	8	be	be	VB
cord-345879-nbfg47x5	71	9	implicated	implicate	VBN
cord-345879-nbfg47x5	71	10	in	in	IN
cord-345879-nbfg47x5	71	11	the	the	DT
cord-345879-nbfg47x5	71	12	thrombotic	thrombotic	JJ
cord-345879-nbfg47x5	71	13	and	and	CC
cord-345879-nbfg47x5	71	14	vascular	vascular	JJ
cord-345879-nbfg47x5	71	15	complications	complication	NNS
cord-345879-nbfg47x5	71	16	of	of	IN
cord-345879-nbfg47x5	71	17	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	71	18	(	(	-LRB-
cord-345879-nbfg47x5	71	19	Farsalinos	Farsalinos	NNP
cord-345879-nbfg47x5	71	20	et	et	NNP
cord-345879-nbfg47x5	71	21	al	al	NNP
cord-345879-nbfg47x5	71	22	.	.	NNP
cord-345879-nbfg47x5	71	23	2020b	2020b	CD
cord-345879-nbfg47x5	71	24	)	)	-RRB-
cord-345879-nbfg47x5	71	25	.	.	.
cord-345879-nbfg47x5	72	1	Nicotine	nicotine	NN
cord-345879-nbfg47x5	72	2	could	could	MD
cord-345879-nbfg47x5	72	3	provide	provide	VB
cord-345879-nbfg47x5	72	4	protection	protection	NN
cord-345879-nbfg47x5	72	5	through	through	IN
cord-345879-nbfg47x5	72	6	a	a	DT
cord-345879-nbfg47x5	72	7	direct	direct	JJ
cord-345879-nbfg47x5	72	8	action	action	NN
cord-345879-nbfg47x5	72	9	on	on	IN
cord-345879-nbfg47x5	72	10	various	various	JJ
cord-345879-nbfg47x5	72	11	nAChRs	nachr	NNS
cord-345879-nbfg47x5	72	12	expressed	express	VBN
cord-345879-nbfg47x5	72	13	in	in	IN
cord-345879-nbfg47x5	72	14	neurons	neuron	NNS
cord-345879-nbfg47x5	72	15	,	,	,
cord-345879-nbfg47x5	72	16	immune	immune	JJ
cord-345879-nbfg47x5	72	17	cells	cell	NNS
cord-345879-nbfg47x5	72	18	,	,	,
cord-345879-nbfg47x5	72	19	macrophages	macrophage	NNS
cord-345879-nbfg47x5	72	20	,	,	,
cord-345879-nbfg47x5	72	21	cardiac	cardiac	JJ
cord-345879-nbfg47x5	72	22	tissue	tissue	NN
cord-345879-nbfg47x5	72	23	,	,	,
cord-345879-nbfg47x5	72	24	lungs	lung	NNS
cord-345879-nbfg47x5	72	25	,	,	,
cord-345879-nbfg47x5	72	26	and	and	CC
cord-345879-nbfg47x5	72	27	blood	blood	NN
cord-345879-nbfg47x5	72	28	vessels	vessel	NNS
cord-345879-nbfg47x5	72	29	(	(	-LRB-
cord-345879-nbfg47x5	72	30	Kawashima	Kawashima	NNP
cord-345879-nbfg47x5	72	31	et	et	FW
cord-345879-nbfg47x5	72	32	al	al	NNP
cord-345879-nbfg47x5	72	33	.	.	NNP
cord-345879-nbfg47x5	72	34	2007	2007	CD
cord-345879-nbfg47x5	72	35	)	)	-RRB-
cord-345879-nbfg47x5	72	36	.	.	.
cord-345879-nbfg47x5	73	1	Changeux	Changeux	NNP
cord-345879-nbfg47x5	73	2	et	et	FW
cord-345879-nbfg47x5	73	3	al	al	NNP
cord-345879-nbfg47x5	73	4	.	.	.
cord-345879-nbfg47x5	74	1	(	(	-LRB-
cord-345879-nbfg47x5	74	2	Changeux	Changeux	NNP
cord-345879-nbfg47x5	74	3	et	et	FW
cord-345879-nbfg47x5	74	4	al	al	NNP
cord-345879-nbfg47x5	74	5	.	.	NNP
cord-345879-nbfg47x5	74	6	2020	2020	CD
cord-345879-nbfg47x5	74	7	)	)	-RRB-
cord-345879-nbfg47x5	74	8	hypothesize	hypothesize	VBP
cord-345879-nbfg47x5	74	9	that	that	IN
cord-345879-nbfg47x5	74	10	the	the	DT
cord-345879-nbfg47x5	74	11	nAChR	nAChR	NNP
cord-345879-nbfg47x5	74	12	plays	play	VBZ
cord-345879-nbfg47x5	74	13	a	a	DT
cord-345879-nbfg47x5	74	14	key	key	JJ
cord-345879-nbfg47x5	74	15	role	role	NN
cord-345879-nbfg47x5	74	16	in	in	IN
cord-345879-nbfg47x5	74	17	the	the	DT
cord-345879-nbfg47x5	74	18	pathophysiology	pathophysiology	NN
cord-345879-nbfg47x5	74	19	of	of	IN
cord-345879-nbfg47x5	74	20	Covid-19	covid-19	JJ
cord-345879-nbfg47x5	74	21	infection	infection	NN
cord-345879-nbfg47x5	74	22	and	and	CC
cord-345879-nbfg47x5	74	23	might	may	MD
cord-345879-nbfg47x5	74	24	represent	represent	VB
cord-345879-nbfg47x5	74	25	a	a	DT
cord-345879-nbfg47x5	74	26	target	target	NN
cord-345879-nbfg47x5	74	27	for	for	IN
cord-345879-nbfg47x5	74	28	the	the	DT
cord-345879-nbfg47x5	74	29	prevention	prevention	NN
cord-345879-nbfg47x5	74	30	and	and	CC
cord-345879-nbfg47x5	74	31	control	control	NN
cord-345879-nbfg47x5	74	32	of	of	IN
cord-345879-nbfg47x5	74	33	Covid-19	covid-19	JJ
cord-345879-nbfg47x5	74	34	infection	infection	NN
cord-345879-nbfg47x5	74	35	.	.	.
cord-345879-nbfg47x5	75	1	There	there	EX
cord-345879-nbfg47x5	75	2	is	be	VBZ
cord-345879-nbfg47x5	75	3	a	a	DT
cord-345879-nbfg47x5	75	4	structural	structural	JJ
cord-345879-nbfg47x5	75	5	evidence	evidence	NN
cord-345879-nbfg47x5	75	6	supporting	support	VBG
cord-345879-nbfg47x5	75	7	the	the	DT
cord-345879-nbfg47x5	75	8	hypothesis	hypothesis	NN
cord-345879-nbfg47x5	75	9	that	that	IN
cord-345879-nbfg47x5	75	10	SARS	SARS	NNP
cord-345879-nbfg47x5	75	11	-	-	HYPH
cord-345879-nbfg47x5	75	12	Cov-2	Cov-2	NNP
cord-345879-nbfg47x5	75	13	virus	virus	NN
cord-345879-nbfg47x5	75	14	is	be	VBZ
cord-345879-nbfg47x5	75	15	a	a	DT
cord-345879-nbfg47x5	75	16	nAChR	nAChR	NNP
cord-345879-nbfg47x5	75	17	blocker	blocker	NN
cord-345879-nbfg47x5	75	18	(	(	-LRB-
cord-345879-nbfg47x5	75	19	Changeux	Changeux	NNP
cord-345879-nbfg47x5	75	20	et	et	FW
cord-345879-nbfg47x5	75	21	al	al	NNP
cord-345879-nbfg47x5	75	22	.	.	NNP
cord-345879-nbfg47x5	75	23	2020	2020	CD
cord-345879-nbfg47x5	75	24	)	)	-RRB-
cord-345879-nbfg47x5	75	25	.	.	.
cord-345879-nbfg47x5	76	1	Consequently	consequently	RB
cord-345879-nbfg47x5	76	2	,	,	,
cord-345879-nbfg47x5	76	3	α7nAChRs	α7nachrs	XX
cord-345879-nbfg47x5	76	4	could	could	MD
cord-345879-nbfg47x5	76	5	be	be	VB
cord-345879-nbfg47x5	76	6	a	a	DT
cord-345879-nbfg47x5	76	7	candidate	candidate	NN
cord-345879-nbfg47x5	76	8	since	since	IN
cord-345879-nbfg47x5	76	9	they	-PRON-	PRP
cord-345879-nbfg47x5	76	10	are	be	VBP
cord-345879-nbfg47x5	76	11	expressed	express	VBN
cord-345879-nbfg47x5	76	12	on	on	IN
cord-345879-nbfg47x5	76	13	immune	immune	JJ
cord-345879-nbfg47x5	76	14	cells	cell	NNS
cord-345879-nbfg47x5	76	15	regulating	regulate	VBG
cord-345879-nbfg47x5	76	16	antigen	antigen	NN
cord-345879-nbfg47x5	76	17	-	-	HYPH
cord-345879-nbfg47x5	76	18	specific	specific	JJ
cord-345879-nbfg47x5	76	19	antibody	antibody	NN
cord-345879-nbfg47x5	76	20	and	and	CC
cord-345879-nbfg47x5	76	21	proinflammatory	proinflammatory	JJ
cord-345879-nbfg47x5	76	22	cytokine	cytokine	NN
cord-345879-nbfg47x5	76	23	production	production	NN
cord-345879-nbfg47x5	76	24	and	and	CC
cord-345879-nbfg47x5	76	25	likely	likely	RB
cord-345879-nbfg47x5	76	26	regulate	regulate	VB
cord-345879-nbfg47x5	76	27	the	the	DT
cord-345879-nbfg47x5	76	28	intensity	intensity	NN
cord-345879-nbfg47x5	76	29	of	of	IN
cord-345879-nbfg47x5	76	30	immune	immune	JJ
cord-345879-nbfg47x5	76	31	responses	response	NNS
cord-345879-nbfg47x5	76	32	(	(	-LRB-
cord-345879-nbfg47x5	76	33	Mashimo	Mashimo	NNP
cord-345879-nbfg47x5	76	34	et	et	FW
cord-345879-nbfg47x5	76	35	al	al	NNP
cord-345879-nbfg47x5	76	36	.	.	NNP
cord-345879-nbfg47x5	76	37	2020	2020	CD
cord-345879-nbfg47x5	76	38	)	)	-RRB-
cord-345879-nbfg47x5	76	39	.	.	.
cord-345879-nbfg47x5	77	1	Numerous	numerous	JJ
cord-345879-nbfg47x5	77	2	immune	immune	JJ
cord-345879-nbfg47x5	77	3	cells	cell	NNS
cord-345879-nbfg47x5	77	4	,	,	,
cord-345879-nbfg47x5	77	5	including	include	VBG
cord-345879-nbfg47x5	77	6	T	t	NN
cord-345879-nbfg47x5	77	7	and	and	CC
cord-345879-nbfg47x5	77	8	B	b	NN
cord-345879-nbfg47x5	77	9	cells	cell	NNS
cord-345879-nbfg47x5	77	10	,	,	,
cord-345879-nbfg47x5	77	11	macrophages	macrophage	NNS
cord-345879-nbfg47x5	77	12	,	,	,
cord-345879-nbfg47x5	77	13	and	and	CC
cord-345879-nbfg47x5	77	14	dendritic	dendritic	JJ
cord-345879-nbfg47x5	77	15	cells	cell	NNS
cord-345879-nbfg47x5	77	16	,	,	,
cord-345879-nbfg47x5	77	17	express	express	VB
cord-345879-nbfg47x5	77	18	the	the	DT
cord-345879-nbfg47x5	77	19	cholinergic	cholinergic	JJ
cord-345879-nbfg47x5	77	20	system	system	NN
cord-345879-nbfg47x5	77	21	(	(	-LRB-
cord-345879-nbfg47x5	77	22	Fujii	Fujii	NNP
cord-345879-nbfg47x5	77	23	et	et	NNP
cord-345879-nbfg47x5	77	24	al	al	NNP
cord-345879-nbfg47x5	77	25	.	.	.
cord-345879-nbfg47x5	77	26	2017	2017	CD
cord-345879-nbfg47x5	77	27	)	)	-RRB-
cord-345879-nbfg47x5	77	28	.	.	.
cord-345879-nbfg47x5	78	1	These	these	DT
cord-345879-nbfg47x5	78	2	immune	immune	JJ
cord-345879-nbfg47x5	78	3	cells	cell	NNS
cord-345879-nbfg47x5	78	4	belong	belong	VBP
cord-345879-nbfg47x5	78	5	to	to	IN
cord-345879-nbfg47x5	78	6	the	the	DT
cord-345879-nbfg47x5	78	7	non	non	JJ
cord-345879-nbfg47x5	78	8	-	-	JJ
cord-345879-nbfg47x5	78	9	neuronal	neuronal	JJ
cord-345879-nbfg47x5	78	10	cholinergic	cholinergic	JJ
cord-345879-nbfg47x5	78	11	system	system	NN
cord-345879-nbfg47x5	78	12	and	and	CC
cord-345879-nbfg47x5	78	13	play	play	VB
cord-345879-nbfg47x5	78	14	a	a	DT
cord-345879-nbfg47x5	78	15	key	key	JJ
cord-345879-nbfg47x5	78	16	role	role	NN
cord-345879-nbfg47x5	78	17	in	in	IN
cord-345879-nbfg47x5	78	18	regulating	regulate	VBG
cord-345879-nbfg47x5	78	19	immune	immune	JJ
cord-345879-nbfg47x5	78	20	function	function	NN
cord-345879-nbfg47x5	78	21	using	use	VBG
cord-345879-nbfg47x5	78	22	ACh	ACh	NNP
cord-345879-nbfg47x5	78	23	acting	act	VBG
cord-345879-nbfg47x5	78	24	on	on	IN
cord-345879-nbfg47x5	78	25	their	-PRON-	PRP$
cord-345879-nbfg47x5	78	26	own	own	JJ
cord-345879-nbfg47x5	78	27	AChRs	achrs	NN
cord-345879-nbfg47x5	78	28	through	through	IN
cord-345879-nbfg47x5	78	29	autocrine	autocrine	NN
cord-345879-nbfg47x5	78	30	and	and	CC
cord-345879-nbfg47x5	78	31	paracrine	paracrine	JJ
cord-345879-nbfg47x5	78	32	pathways	pathway	NNS
cord-345879-nbfg47x5	78	33	.	.	.
cord-345879-nbfg47x5	79	1	Among	among	IN
cord-345879-nbfg47x5	79	2	these	these	DT
cord-345879-nbfg47x5	79	3	AChRs	achr	NNS
cord-345879-nbfg47x5	79	4	,	,	,
cord-345879-nbfg47x5	79	5	α7nAChRs	α7nachrs	ADD
cord-345879-nbfg47x5	79	6	play	play	VB
cord-345879-nbfg47x5	79	7	a	a	DT
cord-345879-nbfg47x5	79	8	role	role	NN
cord-345879-nbfg47x5	79	9	in	in	IN
cord-345879-nbfg47x5	79	10	the	the	DT
cord-345879-nbfg47x5	79	11	regulation	regulation	NN
cord-345879-nbfg47x5	79	12	of	of	IN
cord-345879-nbfg47x5	79	13	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	79	14	responses	response	NNS
cord-345879-nbfg47x5	79	15	and	and	CC
cord-345879-nbfg47x5	79	16	immune	immune	JJ
cord-345879-nbfg47x5	79	17	function	function	NN
cord-345879-nbfg47x5	79	18	as	as	IN
cord-345879-nbfg47x5	79	19	reported	report	VBN
cord-345879-nbfg47x5	79	20	by	by	IN
cord-345879-nbfg47x5	79	21	the	the	DT
cord-345879-nbfg47x5	79	22	Tracey	Tracey	NNP
cord-345879-nbfg47x5	79	23	group	group	NN
cord-345879-nbfg47x5	79	24	.	.	.
cord-345879-nbfg47x5	80	1	Thus	thus	RB
cord-345879-nbfg47x5	80	2	,	,	,
cord-345879-nbfg47x5	80	3	targeting	target	VBG
cord-345879-nbfg47x5	80	4	α7nAChR	α7nachr	CD
cord-345879-nbfg47x5	80	5	activity	activity	NN
cord-345879-nbfg47x5	80	6	could	could	MD
cord-345879-nbfg47x5	80	7	be	be	VB
cord-345879-nbfg47x5	80	8	of	of	IN
cord-345879-nbfg47x5	80	9	interest	interest	NN
cord-345879-nbfg47x5	80	10	to	to	TO
cord-345879-nbfg47x5	80	11	modify	modify	VB
cord-345879-nbfg47x5	80	12	immune	immune	JJ
cord-345879-nbfg47x5	80	13	function	function	NN
cord-345879-nbfg47x5	80	14	,	,	,
cord-345879-nbfg47x5	80	15	which	which	WDT
cord-345879-nbfg47x5	80	16	is	be	VBZ
cord-345879-nbfg47x5	80	17	dysregulated	dysregulate	VBN
cord-345879-nbfg47x5	80	18	in	in	IN
cord-345879-nbfg47x5	80	19	COVID-19	covid-19	JJ
cord-345879-nbfg47x5	80	20	infection	infection	NN
cord-345879-nbfg47x5	80	21	where	where	WRB
cord-345879-nbfg47x5	80	22	an	an	DT
cord-345879-nbfg47x5	80	23	immune	immune	JJ
cord-345879-nbfg47x5	80	24	system	system	NN
cord-345879-nbfg47x5	80	25	overreaction	overreaction	NN
cord-345879-nbfg47x5	80	26	or	or	CC
cord-345879-nbfg47x5	80	27	cytokine	cytokine	NN
cord-345879-nbfg47x5	80	28	storm	storm	NN
cord-345879-nbfg47x5	80	29	is	be	VBZ
cord-345879-nbfg47x5	80	30	observed	observe	VBN
cord-345879-nbfg47x5	80	31	(	(	-LRB-
cord-345879-nbfg47x5	80	32	Fig	Fig	NNP
cord-345879-nbfg47x5	80	33	.	.	.
cord-345879-nbfg47x5	80	34	1	1	CD
cord-345879-nbfg47x5	80	35	)	)	-RRB-
cord-345879-nbfg47x5	80	36	.	.	.
cord-345879-nbfg47x5	81	1	In	in	IN
cord-345879-nbfg47x5	81	2	particular	particular	JJ
cord-345879-nbfg47x5	81	3	,	,	,
cord-345879-nbfg47x5	81	4	targeting	target	VBG
cord-345879-nbfg47x5	81	5	the	the	DT
cord-345879-nbfg47x5	81	6	CAP	cap	NN
cord-345879-nbfg47x5	81	7	,	,	,
cord-345879-nbfg47x5	81	8	a	a	DT
cord-345879-nbfg47x5	81	9	mechanism	mechanism	NN
cord-345879-nbfg47x5	81	10	by	by	IN
cord-345879-nbfg47x5	81	11	which	which	WDT
cord-345879-nbfg47x5	81	12	local	local	JJ
cord-345879-nbfg47x5	81	13	inflammation	inflammation	NN
cord-345879-nbfg47x5	81	14	activates	activate	VBZ
cord-345879-nbfg47x5	81	15	the	the	DT
cord-345879-nbfg47x5	81	16	afferent	afferent	JJ
cord-345879-nbfg47x5	81	17	(	(	-LRB-
cord-345879-nbfg47x5	81	18	sensory	sensory	JJ
cord-345879-nbfg47x5	81	19	)	)	-RRB-
cord-345879-nbfg47x5	81	20	fibres	fibre	NNS
cord-345879-nbfg47x5	81	21	of	of	IN
cord-345879-nbfg47x5	81	22	the	the	DT
cord-345879-nbfg47x5	81	23	vagus	vagus	NN
cord-345879-nbfg47x5	81	24	nerve	nerve	NN
cord-345879-nbfg47x5	81	25	to	to	TO
cord-345879-nbfg47x5	81	26	signal	signal	VB
cord-345879-nbfg47x5	81	27	the	the	DT
cord-345879-nbfg47x5	81	28	brain	brain	NN
cord-345879-nbfg47x5	81	29	to	to	TO
cord-345879-nbfg47x5	81	30	trigger	trigger	VB
cord-345879-nbfg47x5	81	31	an	an	DT
cord-345879-nbfg47x5	81	32	antiinflammatory	antiinflammatory	JJ
cord-345879-nbfg47x5	81	33	response	response	NN
cord-345879-nbfg47x5	81	34	through	through	IN
cord-345879-nbfg47x5	81	35	firing	firing	NN
cord-345879-nbfg47x5	81	36	of	of	IN
cord-345879-nbfg47x5	81	37	the	the	DT
cord-345879-nbfg47x5	81	38	efferent	efferent	JJ
cord-345879-nbfg47x5	81	39	vagus	vagus	NN
cord-345879-nbfg47x5	81	40	nerve	nerve	NN
cord-345879-nbfg47x5	82	1	i.e.	i.e.	FW
cord-345879-nbfg47x5	82	2	the	the	DT
cord-345879-nbfg47x5	82	3	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	82	4	reflex	reflex	NN
cord-345879-nbfg47x5	82	5	is	be	VBZ
cord-345879-nbfg47x5	82	6	of	of	IN
cord-345879-nbfg47x5	82	7	interest	interest	NN
cord-345879-nbfg47x5	82	8	(	(	-LRB-
cord-345879-nbfg47x5	82	9	Tracey	Tracey	NNP
cord-345879-nbfg47x5	82	10	2002	2002	CD
cord-345879-nbfg47x5	82	11	)	)	-RRB-
cord-345879-nbfg47x5	82	12	.	.	.
cord-345879-nbfg47x5	83	1	Among	among	IN
cord-345879-nbfg47x5	83	2	the	the	DT
cord-345879-nbfg47x5	83	3	tools	tool	NNS
cord-345879-nbfg47x5	83	4	,	,	,
cord-345879-nbfg47x5	83	5	VNS	VNS	NNP
cord-345879-nbfg47x5	83	6	either	either	CC
cord-345879-nbfg47x5	83	7	invasive	invasive	JJ
cord-345879-nbfg47x5	83	8	at	at	IN
cord-345879-nbfg47x5	83	9	the	the	DT
cord-345879-nbfg47x5	83	10	cervical	cervical	JJ
cord-345879-nbfg47x5	83	11	level	level	NN
cord-345879-nbfg47x5	83	12	,	,	,
cord-345879-nbfg47x5	83	13	validated	validate	VBN
cord-345879-nbfg47x5	83	14	in	in	IN
cord-345879-nbfg47x5	83	15	the	the	DT
cord-345879-nbfg47x5	83	16	treatment	treatment	NN
cord-345879-nbfg47x5	83	17	of	of	IN
cord-345879-nbfg47x5	83	18	drug	drug	NN
cord-345879-nbfg47x5	83	19	resistant	resistant	JJ
cord-345879-nbfg47x5	83	20	epilepsy	epilepsy	NN
cord-345879-nbfg47x5	83	21	and	and	CC
cord-345879-nbfg47x5	83	22	depression	depression	NN
cord-345879-nbfg47x5	83	23	,	,	,
cord-345879-nbfg47x5	83	24	or	or	CC
cord-345879-nbfg47x5	83	25	non	non	JJ
cord-345879-nbfg47x5	83	26	-	-	JJ
cord-345879-nbfg47x5	83	27	invasive	invasive	JJ
cord-345879-nbfg47x5	83	28	through	through	IN
cord-345879-nbfg47x5	83	29	transcutaneous	transcutaneous	JJ
cord-345879-nbfg47x5	83	30	auricular	auricular	JJ
cord-345879-nbfg47x5	83	31	or	or	CC
cord-345879-nbfg47x5	83	32	cervical	cervical	JJ
cord-345879-nbfg47x5	83	33	stimulation	stimulation	NN
cord-345879-nbfg47x5	83	34	could	could	MD
cord-345879-nbfg47x5	83	35	be	be	VB
cord-345879-nbfg47x5	83	36	of	of	IN
cord-345879-nbfg47x5	83	37	interest	interest	NN
cord-345879-nbfg47x5	83	38	.	.	.
cord-345879-nbfg47x5	84	1	VNS	VNS	NNP
cord-345879-nbfg47x5	84	2	is	be	VBZ
cord-345879-nbfg47x5	84	3	a	a	DT
cord-345879-nbfg47x5	84	4	non	non	JJ
cord-345879-nbfg47x5	84	5	-	-	JJ
cord-345879-nbfg47x5	84	6	drug	drug	JJ
cord-345879-nbfg47x5	84	7	therapy	therapy	NN
cord-345879-nbfg47x5	84	8	able	able	JJ
cord-345879-nbfg47x5	84	9	to	to	TO
cord-345879-nbfg47x5	84	10	stimulate	stimulate	VB
cord-345879-nbfg47x5	84	11	the	the	DT
cord-345879-nbfg47x5	84	12	CAP	cap	NN
cord-345879-nbfg47x5	84	13	thus	thus	RB
cord-345879-nbfg47x5	84	14	dampening	dampen	VBG
cord-345879-nbfg47x5	84	15	the	the	DT
cord-345879-nbfg47x5	84	16	release	release	NN
cord-345879-nbfg47x5	84	17	of	of	IN
cord-345879-nbfg47x5	84	18	proinflammatory	proinflammatory	JJ
cord-345879-nbfg47x5	84	19	cytokines	cytokine	NNS
cord-345879-nbfg47x5	84	20	such	such	JJ
cord-345879-nbfg47x5	84	21	as	as	IN
cord-345879-nbfg47x5	84	22	TNF	TNF	NNP
cord-345879-nbfg47x5	84	23	,	,	,
cord-345879-nbfg47x5	84	24	IL6	IL6	NNP
cord-345879-nbfg47x5	84	25	,	,	,
cord-345879-nbfg47x5	84	26	IL1β	IL1β	NNP
cord-345879-nbfg47x5	84	27	.	.	.
cord-345879-nbfg47x5	85	1	These	these	DT
cord-345879-nbfg47x5	85	2	pro	pro	JJ
cord-345879-nbfg47x5	85	3	-	-	JJ
cord-345879-nbfg47x5	85	4	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	85	5	cytokines	cytokine	NNS
cord-345879-nbfg47x5	85	6	are	be	VBP
cord-345879-nbfg47x5	85	7	also	also	RB
cord-345879-nbfg47x5	85	8	involved	involve	VBN
cord-345879-nbfg47x5	85	9	in	in	IN
cord-345879-nbfg47x5	85	10	the	the	DT
cord-345879-nbfg47x5	85	11	pathogeny	pathogeny	NN
cord-345879-nbfg47x5	85	12	of	of	IN
cord-345879-nbfg47x5	85	13	chronic	chronic	JJ
cord-345879-nbfg47x5	85	14	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	85	15	disease	disease	NN
cord-345879-nbfg47x5	85	16	such	such	JJ
cord-345879-nbfg47x5	85	17	as	as	IN
cord-345879-nbfg47x5	85	18	IBD	IBD	NNP
cord-345879-nbfg47x5	85	19	and	and	CC
cord-345879-nbfg47x5	85	20	rheumatoid	rheumatoid	NN
cord-345879-nbfg47x5	85	21	arthritis	arthritis	NN
cord-345879-nbfg47x5	85	22	(	(	-LRB-
cord-345879-nbfg47x5	85	23	RA	RA	NNP
cord-345879-nbfg47x5	85	24	)	)	-RRB-
cord-345879-nbfg47x5	85	25	.	.	.
cord-345879-nbfg47x5	86	1	VNS	VNS	NNP
cord-345879-nbfg47x5	86	2	has	have	VBZ
cord-345879-nbfg47x5	86	3	recently	recently	RB
cord-345879-nbfg47x5	86	4	shown	show	VBN
cord-345879-nbfg47x5	86	5	its	-PRON-	PRP$
cord-345879-nbfg47x5	86	6	anti	anti	JJ
cord-345879-nbfg47x5	86	7	-	-	JJ
cord-345879-nbfg47x5	86	8	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	86	9	effect	effect	NN
cord-345879-nbfg47x5	86	10	in	in	IN
cord-345879-nbfg47x5	86	11	IBD	IBD	NNP
cord-345879-nbfg47x5	86	12	(	(	-LRB-
cord-345879-nbfg47x5	86	13	Bonaz	Bonaz	NNP
cord-345879-nbfg47x5	86	14	et	et	NNP
cord-345879-nbfg47x5	86	15	al	al	NNP
cord-345879-nbfg47x5	86	16	.	.	.
cord-345879-nbfg47x5	86	17	2016	2016	CD
cord-345879-nbfg47x5	86	18	;	;	:
cord-345879-nbfg47x5	86	19	Sinniger	Sinniger	NNP
cord-345879-nbfg47x5	86	20	et	et	NNP
cord-345879-nbfg47x5	86	21	al	al	NNP
cord-345879-nbfg47x5	86	22	.	.	NNP
cord-345879-nbfg47x5	86	23	2020	2020	CD
cord-345879-nbfg47x5	86	24	)	)	-RRB-
cord-345879-nbfg47x5	86	25	and	and	CC
cord-345879-nbfg47x5	86	26	RA	RA	NNP
cord-345879-nbfg47x5	86	27	(	(	-LRB-
cord-345879-nbfg47x5	86	28	Koopman	Koopman	NNP
cord-345879-nbfg47x5	86	29	et	et	NNP
cord-345879-nbfg47x5	86	30	al	al	NNP
cord-345879-nbfg47x5	86	31	.	.	.
cord-345879-nbfg47x5	87	1	2016a	2016a	LS
cord-345879-nbfg47x5	87	2	)	)	-RRB-
cord-345879-nbfg47x5	87	3	especially	especially	RB
cord-345879-nbfg47x5	87	4	by	by	IN
cord-345879-nbfg47x5	87	5	decreasing	decrease	VBG
cord-345879-nbfg47x5	87	6	the	the	DT
cord-345879-nbfg47x5	87	7	plasmatic	plasmatic	JJ
cord-345879-nbfg47x5	87	8	level	level	NN
cord-345879-nbfg47x5	87	9	of	of	IN
cord-345879-nbfg47x5	87	10	these	these	DT
cord-345879-nbfg47x5	87	11	cytokines	cytokine	NNS
cord-345879-nbfg47x5	87	12	.	.	.
cord-345879-nbfg47x5	88	1	Consequently	consequently	RB
cord-345879-nbfg47x5	88	2	,	,	,
cord-345879-nbfg47x5	88	3	VNS	VNS	NNP
cord-345879-nbfg47x5	88	4	could	could	MD
cord-345879-nbfg47x5	88	5	be	be	VB
cord-345879-nbfg47x5	88	6	of	of	IN
cord-345879-nbfg47x5	88	7	interest	interest	NN
cord-345879-nbfg47x5	88	8	in	in	IN
cord-345879-nbfg47x5	88	9	the	the	DT
cord-345879-nbfg47x5	88	10	management	management	NN
cord-345879-nbfg47x5	88	11	of	of	IN
cord-345879-nbfg47x5	88	12	patients	patient	NNS
cord-345879-nbfg47x5	88	13	with	with	IN
cord-345879-nbfg47x5	88	14	SARS	SARS	NNP
cord-345879-nbfg47x5	88	15	-	-	HYPH
cord-345879-nbfg47x5	88	16	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	88	17	infection	infection	NN
cord-345879-nbfg47x5	88	18	based	base	VBN
cord-345879-nbfg47x5	88	19	on	on	IN
cord-345879-nbfg47x5	88	20	its	-PRON-	PRP$
cord-345879-nbfg47x5	88	21	modulatory	modulatory	JJ
cord-345879-nbfg47x5	88	22	effect	effect	NN
cord-345879-nbfg47x5	88	23	on	on	IN
cord-345879-nbfg47x5	88	24	cytokine	cytokine	NN
cord-345879-nbfg47x5	88	25	release	release	NN
cord-345879-nbfg47x5	88	26	.	.	.
cord-345879-nbfg47x5	89	1	Indeed	indeed	RB
cord-345879-nbfg47x5	89	2	,	,	,
cord-345879-nbfg47x5	89	3	through	through	IN
cord-345879-nbfg47x5	89	4	the	the	DT
cord-345879-nbfg47x5	89	5	wide	wide	JJ
cord-345879-nbfg47x5	89	6	innervation	innervation	NN
cord-345879-nbfg47x5	89	7	of	of	IN
cord-345879-nbfg47x5	89	8	the	the	DT
cord-345879-nbfg47x5	89	9	organism	organism	NN
cord-345879-nbfg47x5	89	10	by	by	IN
cord-345879-nbfg47x5	89	11	the	the	DT
cord-345879-nbfg47x5	89	12	vagus	vagus	NN
cord-345879-nbfg47x5	89	13	nerve	nerve	NN
cord-345879-nbfg47x5	89	14	,	,	,
cord-345879-nbfg47x5	89	15	especially	especially	RB
cord-345879-nbfg47x5	89	16	the	the	DT
cord-345879-nbfg47x5	89	17	lungs	lung	NNS
cord-345879-nbfg47x5	89	18	and	and	CC
cord-345879-nbfg47x5	89	19	GI	GI	NNP
cord-345879-nbfg47x5	89	20	tract	tract	NN
cord-345879-nbfg47x5	89	21	,	,	,
cord-345879-nbfg47x5	89	22	VNS	VNS	NNP
cord-345879-nbfg47x5	89	23	is	be	VBZ
cord-345879-nbfg47x5	89	24	a	a	DT
cord-345879-nbfg47x5	89	25	candidate	candidate	NN
cord-345879-nbfg47x5	89	26	as	as	IN
cord-345879-nbfg47x5	89	27	a	a	DT
cord-345879-nbfg47x5	89	28	treatment	treatment	NN
cord-345879-nbfg47x5	89	29	with	with	IN
cord-345879-nbfg47x5	89	30	few	few	JJ
cord-345879-nbfg47x5	89	31	side	side	NN
cord-345879-nbfg47x5	89	32	effects	effect	NNS
cord-345879-nbfg47x5	89	33	as	as	IN
cord-345879-nbfg47x5	89	34	reported	report	VBN
cord-345879-nbfg47x5	89	35	in	in	IN
cord-345879-nbfg47x5	89	36	epilepsy	epilepsy	NN
cord-345879-nbfg47x5	89	37	(	(	-LRB-
cord-345879-nbfg47x5	89	38	Boon	Boon	NNP
cord-345879-nbfg47x5	89	39	et	et	NNP
cord-345879-nbfg47x5	89	40	al	al	NNP
cord-345879-nbfg47x5	89	41	.	.	.
cord-345879-nbfg47x5	89	42	2018	2018	CD
cord-345879-nbfg47x5	89	43	)	)	-RRB-
cord-345879-nbfg47x5	89	44	.	.	.
cord-345879-nbfg47x5	90	1	Indeed	indeed	RB
cord-345879-nbfg47x5	90	2	,	,	,
cord-345879-nbfg47x5	90	3	through	through	IN
cord-345879-nbfg47x5	90	4	the	the	DT
cord-345879-nbfg47x5	90	5	activation	activation	NN
cord-345879-nbfg47x5	90	6	of	of	IN
cord-345879-nbfg47x5	90	7	α7nAChRs	α7nachr	NNS
cord-345879-nbfg47x5	90	8	of	of	IN
cord-345879-nbfg47x5	90	9	macrophages	macrophage	NNS
cord-345879-nbfg47x5	90	10	by	by	IN
cord-345879-nbfg47x5	90	11	VNS	VNS	NNP
cord-345879-nbfg47x5	90	12	at	at	IN
cord-345879-nbfg47x5	90	13	the	the	DT
cord-345879-nbfg47x5	90	14	level	level	NN
cord-345879-nbfg47x5	90	15	of	of	IN
cord-345879-nbfg47x5	90	16	the	the	DT
cord-345879-nbfg47x5	90	17	digestive	digestive	JJ
cord-345879-nbfg47x5	90	18	system	system	NN
cord-345879-nbfg47x5	90	19	,	,	,
cord-345879-nbfg47x5	90	20	the	the	DT
cord-345879-nbfg47x5	90	21	lungs	lung	NNS
cord-345879-nbfg47x5	90	22	and	and	CC
cord-345879-nbfg47x5	90	23	the	the	DT
cord-345879-nbfg47x5	90	24	spleen	spleen	NN
cord-345879-nbfg47x5	90	25	,	,	,
cord-345879-nbfg47x5	90	26	VNS	VNS	NNP
cord-345879-nbfg47x5	90	27	could	could	MD
cord-345879-nbfg47x5	90	28	dampen	dampen	VB
cord-345879-nbfg47x5	90	29	the	the	DT
cord-345879-nbfg47x5	90	30	cytokine	cytokine	NN
cord-345879-nbfg47x5	90	31	storm	storm	NN
cord-345879-nbfg47x5	90	32	observed	observe	VBD
cord-345879-nbfg47x5	90	33	in	in	IN
cord-345879-nbfg47x5	90	34	patients	patient	NNS
cord-345879-nbfg47x5	90	35	with	with	IN
cord-345879-nbfg47x5	90	36	severe	severe	JJ
cord-345879-nbfg47x5	90	37	Symptoms	symptom	NNS
cord-345879-nbfg47x5	90	38	.	.	.
cord-345879-nbfg47x5	91	1	vagus	vagus	JJ
cord-345879-nbfg47x5	91	2	nerve	nerve	NN
cord-345879-nbfg47x5	91	3	fibers	fiber	NNS
cord-345879-nbfg47x5	91	4	are	be	VBP
cord-345879-nbfg47x5	91	5	present	present	JJ
cord-345879-nbfg47x5	91	6	in	in	IN
cord-345879-nbfg47x5	91	7	the	the	DT
cord-345879-nbfg47x5	91	8	human	human	JJ
cord-345879-nbfg47x5	91	9	lung	lung	NN
cord-345879-nbfg47x5	91	10	,	,	,
cord-345879-nbfg47x5	91	11	especially	especially	RB
cord-345879-nbfg47x5	91	12	in	in	IN
cord-345879-nbfg47x5	91	13	the	the	DT
cord-345879-nbfg47x5	91	14	alveoli	alveolus	NNS
cord-345879-nbfg47x5	91	15	(	(	-LRB-
cord-345879-nbfg47x5	91	16	Fox	Fox	NNP
cord-345879-nbfg47x5	91	17	et	et	FW
cord-345879-nbfg47x5	91	18	al	al	NNP
cord-345879-nbfg47x5	91	19	.	.	.
cord-345879-nbfg47x5	91	20	1980	1980	CD
cord-345879-nbfg47x5	91	21	)	)	-RRB-
cord-345879-nbfg47x5	91	22	.	.	.
cord-345879-nbfg47x5	92	1	Alveolar	alveolar	NN
cord-345879-nbfg47x5	92	2	macrophages	macrophage	NNS
cord-345879-nbfg47x5	92	3	,	,	,
cord-345879-nbfg47x5	92	4	epithelial	epithelial	JJ
cord-345879-nbfg47x5	92	5	cells	cell	NNS
cord-345879-nbfg47x5	92	6	and	and	CC
cord-345879-nbfg47x5	92	7	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	92	8	infiltrated	infiltrate	VBN
cord-345879-nbfg47x5	92	9	neutrophils	neutrophil	NNS
cord-345879-nbfg47x5	92	10	express	express	VBP
cord-345879-nbfg47x5	92	11	α7nAChR	α7nachr	CD
cord-345879-nbfg47x5	92	12	and	and	CC
cord-345879-nbfg47x5	92	13	could	could	MD
cord-345879-nbfg47x5	92	14	be	be	VB
cord-345879-nbfg47x5	92	15	the	the	DT
cord-345879-nbfg47x5	92	16	players	player	NNS
cord-345879-nbfg47x5	92	17	at	at	IN
cord-345879-nbfg47x5	92	18	efferent	efferent	JJ
cord-345879-nbfg47x5	92	19	arm	arm	NN
cord-345879-nbfg47x5	92	20	of	of	IN
cord-345879-nbfg47x5	92	21	pulmonary	pulmonary	JJ
cord-345879-nbfg47x5	92	22	parasympathetic	parasympathetic	JJ
cord-345879-nbfg47x5	92	23	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	92	24	reflex	reflex	NN
cord-345879-nbfg47x5	93	1	(	(	-LRB-
cord-345879-nbfg47x5	93	2	Su	Su	NNP
cord-345879-nbfg47x5	93	3	et	et	FW
cord-345879-nbfg47x5	93	4	al	al	NNP
cord-345879-nbfg47x5	93	5	.	.	NNP
cord-345879-nbfg47x5	93	6	2010	2010	CD
cord-345879-nbfg47x5	93	7	)	)	-RRB-
cord-345879-nbfg47x5	93	8	.	.	.
cord-345879-nbfg47x5	94	1	The	the	DT
cord-345879-nbfg47x5	94	2	vagus	vagus	NN
cord-345879-nbfg47x5	94	3	nerve	nerve	NN
cord-345879-nbfg47x5	94	4	plays	play	VBZ
cord-345879-nbfg47x5	94	5	an	an	DT
cord-345879-nbfg47x5	94	6	important	important	JJ
cord-345879-nbfg47x5	94	7	role	role	NN
cord-345879-nbfg47x5	94	8	in	in	IN
cord-345879-nbfg47x5	94	9	pulmonary	pulmonary	JJ
cord-345879-nbfg47x5	94	10	inflammation	inflammation	NN
cord-345879-nbfg47x5	94	11	(	(	-LRB-
cord-345879-nbfg47x5	94	12	dos	do	NNS
cord-345879-nbfg47x5	94	13	Santos	Santos	NNP
cord-345879-nbfg47x5	94	14	et	et	FW
cord-345879-nbfg47x5	94	15	al	al	NNP
cord-345879-nbfg47x5	94	16	.	.	NNP
cord-345879-nbfg47x5	94	17	2011	2011	CD
cord-345879-nbfg47x5	94	18	)	)	-RRB-
cord-345879-nbfg47x5	94	19	.	.	.
cord-345879-nbfg47x5	95	1	The	the	DT
cord-345879-nbfg47x5	95	2	lung	lung	NN
cord-345879-nbfg47x5	95	3	tissue	tissue	NN
cord-345879-nbfg47x5	95	4	expresses	express	VBZ
cord-345879-nbfg47x5	95	5	the	the	DT
cord-345879-nbfg47x5	95	6	cholinergic	cholinergic	JJ
cord-345879-nbfg47x5	95	7	system	system	NN
cord-345879-nbfg47x5	95	8	including	include	VBG
cord-345879-nbfg47x5	95	9	nAChRs	nAChRs	NNP
cord-345879-nbfg47x5	95	10	involved	involve	VBN
cord-345879-nbfg47x5	95	11	in	in	IN
cord-345879-nbfg47x5	95	12	the	the	DT
cord-345879-nbfg47x5	95	13	pulmonary	pulmonary	JJ
cord-345879-nbfg47x5	95	14	parasympathetic	parasympathetic	JJ
cord-345879-nbfg47x5	95	15	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	95	16	reflex	reflex	NN
cord-345879-nbfg47x5	96	1	(	(	-LRB-
cord-345879-nbfg47x5	96	2	Yang	Yang	NNP
cord-345879-nbfg47x5	96	3	et	et	NNP
cord-345879-nbfg47x5	96	4	al	al	NNP
cord-345879-nbfg47x5	96	5	.	.	NNP
cord-345879-nbfg47x5	96	6	2014	2014	CD
cord-345879-nbfg47x5	96	7	)	)	-RRB-
cord-345879-nbfg47x5	96	8	.	.	.
cord-345879-nbfg47x5	97	1	VNS	VNS	NNP
cord-345879-nbfg47x5	97	2	is	be	VBZ
cord-345879-nbfg47x5	97	3	capable	capable	JJ
cord-345879-nbfg47x5	97	4	to	to	TO
cord-345879-nbfg47x5	97	5	regulate	regulate	VB
cord-345879-nbfg47x5	97	6	disequilibrium	disequilibrium	NN
cord-345879-nbfg47x5	97	7	of	of	IN
cord-345879-nbfg47x5	97	8	the	the	DT
cord-345879-nbfg47x5	97	9	autonomic	autonomic	JJ
cord-345879-nbfg47x5	97	10	nervous	nervous	JJ
cord-345879-nbfg47x5	97	11	system	system	NN
cord-345879-nbfg47x5	97	12	(	(	-LRB-
cord-345879-nbfg47x5	97	13	high	high	JJ
cord-345879-nbfg47x5	97	14	sympathetic	sympathetic	JJ
cord-345879-nbfg47x5	97	15	nervous	nervous	JJ
cord-345879-nbfg47x5	97	16	activity	activity	NN
cord-345879-nbfg47x5	97	17	and	and	CC
cord-345879-nbfg47x5	97	18	low	low	JJ
cord-345879-nbfg47x5	97	19	parasympathetic	parasympathetic	JJ
cord-345879-nbfg47x5	97	20	nervous	nervous	JJ
cord-345879-nbfg47x5	97	21	activity	activity	NN
cord-345879-nbfg47x5	97	22	)	)	-RRB-
cord-345879-nbfg47x5	97	23	in	in	IN
cord-345879-nbfg47x5	97	24	an	an	DT
cord-345879-nbfg47x5	97	25	experimental	experimental	JJ
cord-345879-nbfg47x5	97	26	model	model	NN
cord-345879-nbfg47x5	97	27	of	of	IN
cord-345879-nbfg47x5	97	28	acute	acute	JJ
cord-345879-nbfg47x5	97	29	lung	lung	NN
cord-345879-nbfg47x5	97	30	injury	injury	NN
cord-345879-nbfg47x5	97	31	(	(	-LRB-
cord-345879-nbfg47x5	97	32	Liu	Liu	NNP
cord-345879-nbfg47x5	97	33	et	et	NNP
cord-345879-nbfg47x5	97	34	al	al	NNP
cord-345879-nbfg47x5	97	35	.	.	.
cord-345879-nbfg47x5	97	36	2017	2017	CD
cord-345879-nbfg47x5	97	37	)	)	-RRB-
cord-345879-nbfg47x5	97	38	and	and	CC
cord-345879-nbfg47x5	97	39	acts	act	VBZ
cord-345879-nbfg47x5	97	40	through	through	IN
cord-345879-nbfg47x5	97	41	the	the	DT
cord-345879-nbfg47x5	97	42	CAP	cap	NN
cord-345879-nbfg47x5	97	43	,	,	,
cord-345879-nbfg47x5	97	44	by	by	IN
cord-345879-nbfg47x5	97	45	means	mean	NNS
cord-345879-nbfg47x5	97	46	of	of	IN
cord-345879-nbfg47x5	97	47	α7nAChR	α7nachr	CD
cord-345879-nbfg47x5	97	48	to	to	TO
cord-345879-nbfg47x5	97	49	prevent	prevent	VB
cord-345879-nbfg47x5	97	50	lung	lung	NN
cord-345879-nbfg47x5	97	51	injury	injury	NN
cord-345879-nbfg47x5	98	1	(	(	-LRB-
cord-345879-nbfg47x5	98	2	Tarras	Tarras	NNP
cord-345879-nbfg47x5	98	3	et	et	NNP
cord-345879-nbfg47x5	98	4	al	al	NNP
cord-345879-nbfg47x5	98	5	.	.	NNP
cord-345879-nbfg47x5	98	6	2013	2013	CD
cord-345879-nbfg47x5	98	7	)	)	-RRB-
cord-345879-nbfg47x5	98	8	.	.	.
cord-345879-nbfg47x5	99	1	VNS	VNS	NNP
cord-345879-nbfg47x5	99	2	alleviated	alleviate	VBD
cord-345879-nbfg47x5	99	3	lung	lung	NN
cord-345879-nbfg47x5	99	4	injury	injury	NN
cord-345879-nbfg47x5	99	5	through	through	IN
cord-345879-nbfg47x5	99	6	the	the	DT
cord-345879-nbfg47x5	99	7	reduction	reduction	NN
cord-345879-nbfg47x5	99	8	of	of	IN
cord-345879-nbfg47x5	99	9	gut	gut	NN
cord-345879-nbfg47x5	99	10	and	and	CC
cord-345879-nbfg47x5	99	11	lung	lung	NN
cord-345879-nbfg47x5	99	12	permeability	permeability	NN
cord-345879-nbfg47x5	99	13	through	through	IN
cord-345879-nbfg47x5	99	14	nAChR.	nachr.	NN
cord-345879-nbfg47x5	99	15	Regarding	regard	VBG
cord-345879-nbfg47x5	99	16	the	the	DT
cord-345879-nbfg47x5	99	17	choice	choice	NN
cord-345879-nbfg47x5	99	18	of	of	IN
cord-345879-nbfg47x5	99	19	stimulation	stimulation	NN
cord-345879-nbfg47x5	99	20	parameters	parameter	NNS
cord-345879-nbfg47x5	99	21	,	,	,
cord-345879-nbfg47x5	99	22	those	those	DT
cord-345879-nbfg47x5	99	23	classically	classically	RB
cord-345879-nbfg47x5	99	24	used	use	VBN
cord-345879-nbfg47x5	99	25	in	in	IN
cord-345879-nbfg47x5	99	26	epilepsy	epilepsy	NN
cord-345879-nbfg47x5	99	27	could	could	MD
cord-345879-nbfg47x5	99	28	be	be	VB
cord-345879-nbfg47x5	99	29	of	of	IN
cord-345879-nbfg47x5	99	30	interest	interest	NN
cord-345879-nbfg47x5	99	31	.	.	.
cord-345879-nbfg47x5	100	1	In	in	IN
cord-345879-nbfg47x5	100	2	particular	particular	JJ
cord-345879-nbfg47x5	100	3	,	,	,
cord-345879-nbfg47x5	100	4	a	a	DT
cord-345879-nbfg47x5	100	5	high	high	JJ
cord-345879-nbfg47x5	100	6	frequency	frequency	NN
cord-345879-nbfg47x5	100	7	stimulation	stimulation	NN
cord-345879-nbfg47x5	100	8	of	of	IN
cord-345879-nbfg47x5	100	9	20	20	CD
cord-345879-nbfg47x5	100	10	to	to	TO
cord-345879-nbfg47x5	100	11	30	30	CD
cord-345879-nbfg47x5	100	12	Hz	Hz	NNP
cord-345879-nbfg47x5	100	13	,	,	,
cord-345879-nbfg47x5	100	14	used	use	VBN
cord-345879-nbfg47x5	100	15	for	for	IN
cord-345879-nbfg47x5	100	16	epilepsy	epilepsy	NN
cord-345879-nbfg47x5	100	17	,	,	,
cord-345879-nbfg47x5	100	18	is	be	VBZ
cord-345879-nbfg47x5	100	19	known	know	VBN
cord-345879-nbfg47x5	100	20	to	to	TO
cord-345879-nbfg47x5	100	21	target	target	VB
cord-345879-nbfg47x5	100	22	vagal	vagal	JJ
cord-345879-nbfg47x5	100	23	afferents	afferent	NNS
cord-345879-nbfg47x5	100	24	,	,	,
cord-345879-nbfg47x5	100	25	which	which	WDT
cord-345879-nbfg47x5	100	26	represent	represent	VBP
cord-345879-nbfg47x5	100	27	80	80	CD
cord-345879-nbfg47x5	100	28	%	%	NN
cord-345879-nbfg47x5	100	29	of	of	IN
cord-345879-nbfg47x5	100	30	the	the	DT
cord-345879-nbfg47x5	100	31	vagus	vagus	NN
cord-345879-nbfg47x5	100	32	nerve	nerve	NN
cord-345879-nbfg47x5	100	33	fibers	fiber	NNS
cord-345879-nbfg47x5	100	34	(	(	-LRB-
cord-345879-nbfg47x5	100	35	Prechtl	Prechtl	NNP
cord-345879-nbfg47x5	100	36	and	and	CC
cord-345879-nbfg47x5	100	37	Powley	Powley	NNP
cord-345879-nbfg47x5	100	38	1990	1990	CD
cord-345879-nbfg47x5	100	39	)	)	-RRB-
cord-345879-nbfg47x5	100	40	.	.	.
cord-345879-nbfg47x5	101	1	These	these	DT
cord-345879-nbfg47x5	101	2	vagal	vagal	JJ
cord-345879-nbfg47x5	101	3	afferents	afferent	NNS
cord-345879-nbfg47x5	101	4	target	target	VBP
cord-345879-nbfg47x5	101	5	the	the	DT
cord-345879-nbfg47x5	101	6	central	central	JJ
cord-345879-nbfg47x5	101	7	nervous	nervous	JJ
cord-345879-nbfg47x5	101	8	system	system	NN
cord-345879-nbfg47x5	101	9	(	(	-LRB-
cord-345879-nbfg47x5	101	10	CNS	CNS	NNP
cord-345879-nbfg47x5	101	11	)	)	-RRB-
cord-345879-nbfg47x5	101	12	through	through	IN
cord-345879-nbfg47x5	101	13	the	the	DT
cord-345879-nbfg47x5	101	14	nucleus	nucleus	NN
cord-345879-nbfg47x5	101	15	tractus	tractus	NN
cord-345879-nbfg47x5	102	1	solitarius	solitarius	UH
cord-345879-nbfg47x5	102	2	then	then	RB
cord-345879-nbfg47x5	102	3	activating	activate	VBG
cord-345879-nbfg47x5	102	4	the	the	DT
cord-345879-nbfg47x5	102	5	central	central	JJ
cord-345879-nbfg47x5	102	6	autonomic	autonomic	JJ
cord-345879-nbfg47x5	102	7	network	network	NN
cord-345879-nbfg47x5	102	8	(	(	-LRB-
cord-345879-nbfg47x5	102	9	Benarroch	Benarroch	NNP
cord-345879-nbfg47x5	102	10	1993	1993	CD
cord-345879-nbfg47x5	102	11	)	)	-RRB-
cord-345879-nbfg47x5	102	12	,	,	,
cord-345879-nbfg47x5	102	13	which	which	WDT
cord-345879-nbfg47x5	102	14	modulates	modulate	VBZ
cord-345879-nbfg47x5	102	15	the	the	DT
cord-345879-nbfg47x5	102	16	autonomic	autonomic	JJ
cord-345879-nbfg47x5	102	17	nervous	nervous	JJ
cord-345879-nbfg47x5	102	18	system	system	NN
cord-345879-nbfg47x5	102	19	,	,	,
cord-345879-nbfg47x5	102	20	ie	ie	IN
cord-345879-nbfg47x5	102	21	the	the	DT
cord-345879-nbfg47x5	102	22	sympathetic	sympathetic	JJ
cord-345879-nbfg47x5	102	23	and	and	CC
cord-345879-nbfg47x5	102	24	parasympathetic	parasympathetic	JJ
cord-345879-nbfg47x5	102	25	nervous	nervous	JJ
cord-345879-nbfg47x5	102	26	systems	system	NNS
cord-345879-nbfg47x5	102	27	.	.	.
cord-345879-nbfg47x5	103	1	The	the	DT
cord-345879-nbfg47x5	103	2	other	other	JJ
cord-345879-nbfg47x5	103	3	possibility	possibility	NN
cord-345879-nbfg47x5	103	4	would	would	MD
cord-345879-nbfg47x5	103	5	be	be	VB
cord-345879-nbfg47x5	103	6	to	to	TO
cord-345879-nbfg47x5	103	7	use	use	VB
cord-345879-nbfg47x5	103	8	low	low	JJ
cord-345879-nbfg47x5	103	9	-	-	HYPH
cord-345879-nbfg47x5	103	10	frequency	frequency	NN
cord-345879-nbfg47x5	103	11	stimulation	stimulation	NN
cord-345879-nbfg47x5	103	12	of	of	IN
cord-345879-nbfg47x5	103	13	5	5	CD
cord-345879-nbfg47x5	103	14	-	-	SYM
cord-345879-nbfg47x5	103	15	10	10	CD
cord-345879-nbfg47x5	103	16	Hz	Hz	NNP
cord-345879-nbfg47x5	103	17	known	know	VBN
cord-345879-nbfg47x5	103	18	to	to	TO
cord-345879-nbfg47x5	103	19	stimulate	stimulate	VB
cord-345879-nbfg47x5	103	20	vagal	vagal	JJ
cord-345879-nbfg47x5	103	21	efferents	efferent	NNS
cord-345879-nbfg47x5	103	22	,	,	,
cord-345879-nbfg47x5	103	23	and	and	CC
cord-345879-nbfg47x5	103	24	thus	thus	RB
cord-345879-nbfg47x5	103	25	the	the	DT
cord-345879-nbfg47x5	103	26	CAP	cap	NN
cord-345879-nbfg47x5	103	27	,	,	,
cord-345879-nbfg47x5	103	28	although	although	IN
cord-345879-nbfg47x5	103	29	vagal	vagal	JJ
cord-345879-nbfg47x5	103	30	afferents	afferent	NNS
cord-345879-nbfg47x5	103	31	are	be	VBP
cord-345879-nbfg47x5	103	32	also	also	RB
cord-345879-nbfg47x5	103	33	activated	activate	VBN
cord-345879-nbfg47x5	103	34	with	with	IN
cord-345879-nbfg47x5	103	35	such	such	JJ
cord-345879-nbfg47x5	103	36	frequency	frequency	NN
cord-345879-nbfg47x5	104	1	(	(	-LRB-
cord-345879-nbfg47x5	104	2	Reyt	Reyt	NNP
cord-345879-nbfg47x5	104	3	et	et	NNP
cord-345879-nbfg47x5	104	4	al	al	NNP
cord-345879-nbfg47x5	104	5	.	.	NNP
cord-345879-nbfg47x5	104	6	2010	2010	CD
cord-345879-nbfg47x5	104	7	)	)	-RRB-
cord-345879-nbfg47x5	104	8	.	.	.
cord-345879-nbfg47x5	105	1	In	in	IN
cord-345879-nbfg47x5	105	2	fact	fact	NN
cord-345879-nbfg47x5	105	3	,	,	,
cord-345879-nbfg47x5	105	4	activating	activate	VBG
cord-345879-nbfg47x5	105	5	both	both	DT
cord-345879-nbfg47x5	105	6	vagal	vagal	JJ
cord-345879-nbfg47x5	105	7	afferent	afferent	NN
cord-345879-nbfg47x5	105	8	and	and	CC
cord-345879-nbfg47x5	105	9	efferent	efferent	JJ
cord-345879-nbfg47x5	105	10	fibers	fiber	NNS
cord-345879-nbfg47x5	105	11	is	be	VBZ
cord-345879-nbfg47x5	105	12	of	of	IN
cord-345879-nbfg47x5	105	13	interest	interest	NN
cord-345879-nbfg47x5	105	14	to	to	TO
cord-345879-nbfg47x5	105	15	activate	activate	VB
cord-345879-nbfg47x5	105	16	the	the	DT
cord-345879-nbfg47x5	105	17	CAP	cap	NN
cord-345879-nbfg47x5	105	18	(	(	-LRB-
cord-345879-nbfg47x5	105	19	Bonaz	Bonaz	NNP
cord-345879-nbfg47x5	105	20	et	et	NNP
cord-345879-nbfg47x5	105	21	al	al	NNP
cord-345879-nbfg47x5	105	22	.	.	.
cord-345879-nbfg47x5	105	23	2019	2019	CD
cord-345879-nbfg47x5	105	24	)	)	-RRB-
cord-345879-nbfg47x5	105	25	.	.	.
cord-345879-nbfg47x5	106	1	If	if	IN
cord-345879-nbfg47x5	106	2	the	the	DT
cord-345879-nbfg47x5	106	3	optimal	optimal	JJ
cord-345879-nbfg47x5	106	4	VNS	vns	NN
cord-345879-nbfg47x5	106	5	parameters	parameter	NNS
cord-345879-nbfg47x5	106	6	for	for	IN
cord-345879-nbfg47x5	106	7	resolution	resolution	NN
cord-345879-nbfg47x5	106	8	of	of	IN
cord-345879-nbfg47x5	106	9	inflammation	inflammation	NN
cord-345879-nbfg47x5	106	10	are	be	VBP
cord-345879-nbfg47x5	106	11	still	still	RB
cord-345879-nbfg47x5	106	12	unknown	unknown	JJ
cord-345879-nbfg47x5	106	13	,	,	,
cord-345879-nbfg47x5	106	14	Tsaava	Tsaava	NNP
cord-345879-nbfg47x5	106	15	et	et	NNP
cord-345879-nbfg47x5	106	16	al	al	NNP
cord-345879-nbfg47x5	106	17	.	.	.
cord-345879-nbfg47x5	107	1	(	(	-LRB-
cord-345879-nbfg47x5	107	2	Tsaava	Tsaava	NNP
cord-345879-nbfg47x5	107	3	et	et	NNP
cord-345879-nbfg47x5	107	4	al	al	NNP
cord-345879-nbfg47x5	107	5	.	.	NNP
cord-345879-nbfg47x5	107	6	2020	2020	CD
cord-345879-nbfg47x5	107	7	)	)	-RRB-
cord-345879-nbfg47x5	107	8	reported	report	VBD
cord-345879-nbfg47x5	107	9	recently	recently	RB
cord-345879-nbfg47x5	107	10	that	that	IN
cord-345879-nbfg47x5	107	11	specific	specific	JJ
cord-345879-nbfg47x5	107	12	combinations	combination	NNS
cord-345879-nbfg47x5	107	13	of	of	IN
cord-345879-nbfg47x5	107	14	pulse	pulse	NN
cord-345879-nbfg47x5	107	15	width	width	NN
cord-345879-nbfg47x5	107	16	,	,	,
cord-345879-nbfg47x5	107	17	pulse	pulse	NN
cord-345879-nbfg47x5	107	18	amplitude	amplitude	NN
cord-345879-nbfg47x5	107	19	,	,	,
cord-345879-nbfg47x5	107	20	and	and	CC
cord-345879-nbfg47x5	107	21	frequency	frequency	NN
cord-345879-nbfg47x5	107	22	produced	produce	VBD
cord-345879-nbfg47x5	107	23	a	a	DT
cord-345879-nbfg47x5	107	24	significant	significant	JJ
cord-345879-nbfg47x5	107	25	increase	increase	NN
cord-345879-nbfg47x5	107	26	of	of	IN
cord-345879-nbfg47x5	107	27	TNF	TNF	NNP
cord-345879-nbfg47x5	107	28	,	,	,
cord-345879-nbfg47x5	107	29	while	while	IN
cord-345879-nbfg47x5	107	30	other	other	JJ
cord-345879-nbfg47x5	107	31	parameters	parameter	NNS
cord-345879-nbfg47x5	107	32	selectively	selectively	RB
cord-345879-nbfg47x5	107	33	lowered	lower	VBD
cord-345879-nbfg47x5	107	34	serum	serum	NN
cord-345879-nbfg47x5	107	35	TNF	TNF	NNP
cord-345879-nbfg47x5	107	36	levels	level	NNS
cord-345879-nbfg47x5	107	37	,	,	,
cord-345879-nbfg47x5	107	38	as	as	IN
cord-345879-nbfg47x5	107	39	compared	compare	VBN
cord-345879-nbfg47x5	107	40	to	to	IN
cord-345879-nbfg47x5	107	41	sham	sham	NN
cord-345879-nbfg47x5	107	42	-	-	HYPH
cord-345879-nbfg47x5	107	43	stimulated	stimulate	VBN
cord-345879-nbfg47x5	107	44	mice	mouse	NNS
cord-345879-nbfg47x5	107	45	.	.	.
cord-345879-nbfg47x5	108	1	They	-PRON-	PRP
cord-345879-nbfg47x5	108	2	also	also	RB
cord-345879-nbfg47x5	108	3	showed	show	VBD
cord-345879-nbfg47x5	108	4	that	that	IN
cord-345879-nbfg47x5	108	5	serum	serum	NN
cord-345879-nbfg47x5	108	6	levels	level	NNS
cord-345879-nbfg47x5	108	7	of	of	IN
cord-345879-nbfg47x5	108	8	IL-10	IL-10	NNP
cord-345879-nbfg47x5	108	9	were	be	VBD
cord-345879-nbfg47x5	108	10	significantly	significantly	RB
cord-345879-nbfg47x5	108	11	increased	increase	VBN
cord-345879-nbfg47x5	108	12	by	by	IN
cord-345879-nbfg47x5	108	13	select	select	JJ
cord-345879-nbfg47x5	108	14	parameters	parameter	NNS
cord-345879-nbfg47x5	108	15	of	of	IN
cord-345879-nbfg47x5	108	16	neurostimulation	neurostimulation	NN
cord-345879-nbfg47x5	108	17	but	but	CC
cord-345879-nbfg47x5	108	18	were	be	VBD
cord-345879-nbfg47x5	108	19	unchanged	unchanged	JJ
cord-345879-nbfg47x5	108	20	with	with	IN
cord-345879-nbfg47x5	108	21	others	other	NNS
cord-345879-nbfg47x5	108	22	.	.	.
cord-345879-nbfg47x5	109	1	Based	base	VBN
cord-345879-nbfg47x5	109	2	on	on	IN
cord-345879-nbfg47x5	109	3	the	the	DT
cord-345879-nbfg47x5	109	4	anti	anti	JJ
cord-345879-nbfg47x5	109	5	-	-	JJ
cord-345879-nbfg47x5	109	6	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	109	7	effect	effect	NN
cord-345879-nbfg47x5	109	8	of	of	IN
cord-345879-nbfg47x5	109	9	VNS	VNS	NNP
cord-345879-nbfg47x5	109	10	in	in	IN
cord-345879-nbfg47x5	109	11	chronic	chronic	JJ
cord-345879-nbfg47x5	109	12	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	109	13	disorders	disorder	NNS
cord-345879-nbfg47x5	109	14	of	of	IN
cord-345879-nbfg47x5	109	15	the	the	DT
cord-345879-nbfg47x5	109	16	GI	GI	NNP
cord-345879-nbfg47x5	109	17	tract	tract	NN
cord-345879-nbfg47x5	109	18	,	,	,
cord-345879-nbfg47x5	109	19	VNS	VNS	NNP
cord-345879-nbfg47x5	109	20	could	could	MD
cord-345879-nbfg47x5	109	21	have	have	VB
cord-345879-nbfg47x5	109	22	an	an	DT
cord-345879-nbfg47x5	109	23	effect	effect	NN
cord-345879-nbfg47x5	109	24	on	on	IN
cord-345879-nbfg47x5	109	25	digestive	digestive	JJ
cord-345879-nbfg47x5	109	26	manifestations	manifestation	NNS
cord-345879-nbfg47x5	109	27	due	due	JJ
cord-345879-nbfg47x5	109	28	to	to	IN
cord-345879-nbfg47x5	109	29	the	the	DT
cord-345879-nbfg47x5	109	30	virus	virus	NN
cord-345879-nbfg47x5	109	31	.	.	.
cord-345879-nbfg47x5	110	1	Indeed	indeed	RB
cord-345879-nbfg47x5	110	2	,	,	,
cord-345879-nbfg47x5	110	3	SARS	SARS	NNP
cord-345879-nbfg47x5	110	4	-	-	HYPH
cord-345879-nbfg47x5	110	5	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	110	6	infection	infection	NN
cord-345879-nbfg47x5	110	7	in	in	IN
cord-345879-nbfg47x5	110	8	patients	patient	NNS
cord-345879-nbfg47x5	110	9	with	with	IN
cord-345879-nbfg47x5	110	10	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	110	11	induces	induce	VBZ
cord-345879-nbfg47x5	110	12	an	an	DT
cord-345879-nbfg47x5	110	13	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	110	14	response	response	NN
cord-345879-nbfg47x5	110	15	in	in	IN
cord-345879-nbfg47x5	110	16	the	the	DT
cord-345879-nbfg47x5	110	17	gut	gut	NN
cord-345879-nbfg47x5	110	18	,	,	,
cord-345879-nbfg47x5	110	19	as	as	IN
cord-345879-nbfg47x5	110	20	evidenced	evidence	VBN
cord-345879-nbfg47x5	110	21	by	by	IN
cord-345879-nbfg47x5	110	22	diarrhoea	diarrhoea	NN
cord-345879-nbfg47x5	110	23	,	,	,
cord-345879-nbfg47x5	110	24	elevated	elevated	JJ
cord-345879-nbfg47x5	110	25	fecal	fecal	JJ
cord-345879-nbfg47x5	110	26	calprotectin	calprotectin	NNS
cord-345879-nbfg47x5	110	27	(	(	-LRB-
cord-345879-nbfg47x5	110	28	expressed	express	VBN
cord-345879-nbfg47x5	110	29	by	by	IN
cord-345879-nbfg47x5	110	30	neutrophil	neutrophil	NN
cord-345879-nbfg47x5	110	31	granulocytes	granulocyte	NNS
cord-345879-nbfg47x5	110	32	)	)	-RRB-
cord-345879-nbfg47x5	110	33	,	,	,
cord-345879-nbfg47x5	110	34	and	and	CC
cord-345879-nbfg47x5	110	35	a	a	DT
cord-345879-nbfg47x5	110	36	systemic	systemic	JJ
cord-345879-nbfg47x5	110	37	IL-6	IL-6	NNP
cord-345879-nbfg47x5	110	38	response	response	NN
cord-345879-nbfg47x5	110	39	(	(	-LRB-
cord-345879-nbfg47x5	110	40	Effenberger	Effenberger	NNP
cord-345879-nbfg47x5	110	41	et	et	FW
cord-345879-nbfg47x5	110	42	al	al	NNP
cord-345879-nbfg47x5	110	43	.	.	NNP
cord-345879-nbfg47x5	110	44	2020	2020	CD
cord-345879-nbfg47x5	110	45	)	)	-RRB-
cord-345879-nbfg47x5	110	46	.	.	.
cord-345879-nbfg47x5	111	1	It	-PRON-	PRP
cord-345879-nbfg47x5	111	2	is	be	VBZ
cord-345879-nbfg47x5	111	3	currently	currently	RB
cord-345879-nbfg47x5	111	4	unknown	unknown	JJ
cord-345879-nbfg47x5	111	5	if	if	IN
cord-345879-nbfg47x5	111	6	SARS	SARS	NNP
cord-345879-nbfg47x5	111	7	-	-	HYPH
cord-345879-nbfg47x5	111	8	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	111	9	infection	infection	NN
cord-345879-nbfg47x5	111	10	affects	affect	VBZ
cord-345879-nbfg47x5	111	11	the	the	DT
cord-345879-nbfg47x5	111	12	course	course	NN
cord-345879-nbfg47x5	111	13	of	of	IN
cord-345879-nbfg47x5	111	14	IBD	IBD	NNP
cord-345879-nbfg47x5	111	15	patients	patient	NNS
cord-345879-nbfg47x5	111	16	and	and	CC
cord-345879-nbfg47x5	111	17	whether	whether	IN
cord-345879-nbfg47x5	111	18	immunosuppressive	immunosuppressive	JJ
cord-345879-nbfg47x5	111	19	treatment	treatment	NN
cord-345879-nbfg47x5	111	20	affects	affect	VBZ
cord-345879-nbfg47x5	111	21	their	-PRON-	PRP$
cord-345879-nbfg47x5	111	22	susceptibility	susceptibility	NN
cord-345879-nbfg47x5	111	23	to	to	IN
cord-345879-nbfg47x5	111	24	(	(	-LRB-
cord-345879-nbfg47x5	111	25	or	or	CC
cord-345879-nbfg47x5	111	26	the	the	DT
cord-345879-nbfg47x5	111	27	course	course	NN
cord-345879-nbfg47x5	111	28	of	of	IN
cord-345879-nbfg47x5	111	29	)	)	-RRB-
cord-345879-nbfg47x5	111	30	COVID-19	covid-19	VB
cord-345879-nbfg47x5	111	31	,	,	,
cord-345879-nbfg47x5	111	32	but	but	CC
cord-345879-nbfg47x5	111	33	the	the	DT
cord-345879-nbfg47x5	111	34	baseline	baseline	JJ
cord-345879-nbfg47x5	111	35	use	use	NN
cord-345879-nbfg47x5	111	36	of	of	IN
cord-345879-nbfg47x5	111	37	biologics	biologic	NNS
cord-345879-nbfg47x5	111	38	is	be	VBZ
cord-345879-nbfg47x5	111	39	not	not	RB
cord-345879-nbfg47x5	111	40	associated	associate	VBN
cord-345879-nbfg47x5	111	41	with	with	IN
cord-345879-nbfg47x5	111	42	worse	bad	JJR
cord-345879-nbfg47x5	111	43	COVID-19	covid-19	JJ
cord-345879-nbfg47x5	111	44	outcomes	outcome	NNS
cord-345879-nbfg47x5	111	45	in	in	IN
cord-345879-nbfg47x5	111	46	IBD	IBD	NNP
cord-345879-nbfg47x5	111	47	patients	patient	NNS
cord-345879-nbfg47x5	111	48	(	(	-LRB-
cord-345879-nbfg47x5	111	49	Haberman	Haberman	NNP
cord-345879-nbfg47x5	111	50	et	et	NNP
cord-345879-nbfg47x5	111	51	al	al	NNP
cord-345879-nbfg47x5	111	52	.	.	NNP
cord-345879-nbfg47x5	111	53	2020	2020	CD
cord-345879-nbfg47x5	111	54	)	)	-RRB-
cord-345879-nbfg47x5	111	55	.	.	.
cord-345879-nbfg47x5	112	1	However	however	RB
cord-345879-nbfg47x5	112	2	,	,	,
cord-345879-nbfg47x5	112	3	active	active	JJ
cord-345879-nbfg47x5	112	4	IBD	IBD	NNP
cord-345879-nbfg47x5	112	5	,	,	,
cord-345879-nbfg47x5	112	6	older	old	JJR
cord-345879-nbfg47x5	112	7	age	age	NN
cord-345879-nbfg47x5	112	8	and	and	CC
cord-345879-nbfg47x5	112	9	presence	presence	NN
cord-345879-nbfg47x5	112	10	of	of	IN
cord-345879-nbfg47x5	112	11	comorbidities	comorbiditie	NNS
cord-345879-nbfg47x5	112	12	are	be	VBP
cord-345879-nbfg47x5	112	13	associated	associate	VBN
cord-345879-nbfg47x5	112	14	with	with	IN
cord-345879-nbfg47x5	112	15	a	a	DT
cord-345879-nbfg47x5	112	16	higher	high	JJR
cord-345879-nbfg47x5	112	17	risk	risk	NN
cord-345879-nbfg47x5	112	18	of	of	IN
cord-345879-nbfg47x5	112	19	COVID-19	covid-19	JJ
cord-345879-nbfg47x5	112	20	pneumonia	pneumonia	NN
cord-345879-nbfg47x5	112	21	and	and	CC
cord-345879-nbfg47x5	112	22	death	death	NN
cord-345879-nbfg47x5	112	23	in	in	IN
cord-345879-nbfg47x5	112	24	patients	patient	NNS
cord-345879-nbfg47x5	112	25	with	with	IN
cord-345879-nbfg47x5	112	26	IBD	IBD	NNP
cord-345879-nbfg47x5	112	27	(	(	-LRB-
cord-345879-nbfg47x5	112	28	Bezzio	Bezzio	NNP
cord-345879-nbfg47x5	112	29	et	et	NNP
cord-345879-nbfg47x5	112	30	al	al	NNP
cord-345879-nbfg47x5	112	31	.	.	NNP
cord-345879-nbfg47x5	112	32	2020	2020	CD
cord-345879-nbfg47x5	112	33	)	)	-RRB-
cord-345879-nbfg47x5	112	34	.	.	.
cord-345879-nbfg47x5	113	1	The	the	DT
cord-345879-nbfg47x5	113	2	central	central	JJ
cord-345879-nbfg47x5	113	3	effect	effect	NN
cord-345879-nbfg47x5	113	4	of	of	IN
cord-345879-nbfg47x5	113	5	VNS	VNS	NNP
cord-345879-nbfg47x5	113	6	could	could	MD
cord-345879-nbfg47x5	113	7	have	have	VB
cord-345879-nbfg47x5	113	8	also	also	RB
cord-345879-nbfg47x5	113	9	an	an	DT
cord-345879-nbfg47x5	113	10	interest	interest	NN
cord-345879-nbfg47x5	113	11	in	in	IN
cord-345879-nbfg47x5	113	12	the	the	DT
cord-345879-nbfg47x5	113	13	neurological	neurological	JJ
cord-345879-nbfg47x5	113	14	manifestations	manifestation	NNS
cord-345879-nbfg47x5	113	15	of	of	IN
cord-345879-nbfg47x5	113	16	COVID-19	covid-19	NN
cord-345879-nbfg47x5	113	17	which	which	WDT
cord-345879-nbfg47x5	113	18	were	be	VBD
cord-345879-nbfg47x5	113	19	observed	observe	VBN
cord-345879-nbfg47x5	113	20	in~36.4	in~36.4	NNP
cord-345879-nbfg47x5	113	21	%	%	NN
cord-345879-nbfg47x5	113	22	in	in	IN
cord-345879-nbfg47x5	113	23	a	a	DT
cord-345879-nbfg47x5	113	24	case	case	NN
cord-345879-nbfg47x5	113	25	series	series	NN
cord-345879-nbfg47x5	113	26	of	of	IN
cord-345879-nbfg47x5	113	27	214	214	CD
cord-345879-nbfg47x5	113	28	patients	patient	NNS
cord-345879-nbfg47x5	113	29	.	.	.
cord-345879-nbfg47x5	114	1	Indeed	indeed	RB
cord-345879-nbfg47x5	114	2	,	,	,
cord-345879-nbfg47x5	114	3	the	the	DT
cord-345879-nbfg47x5	114	4	intense	intense	JJ
cord-345879-nbfg47x5	114	5	systemic	systemic	JJ
cord-345879-nbfg47x5	114	6	inflammation	inflammation	NN
cord-345879-nbfg47x5	114	7	triggered	trigger	VBN
cord-345879-nbfg47x5	114	8	by	by	IN
cord-345879-nbfg47x5	114	9	SARS	SARS	NNP
cord-345879-nbfg47x5	114	10	-	-	HYPH
cord-345879-nbfg47x5	114	11	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	114	12	infection	infection	NN
cord-345879-nbfg47x5	114	13	may	may	MD
cord-345879-nbfg47x5	114	14	lead	lead	VB
cord-345879-nbfg47x5	114	15	to	to	IN
cord-345879-nbfg47x5	114	16	blood	blood	NN
cord-345879-nbfg47x5	114	17	-	-	HYPH
cord-345879-nbfg47x5	114	18	brain	brain	NN
cord-345879-nbfg47x5	114	19	barrier	barrier	NN
cord-345879-nbfg47x5	114	20	breakdown	breakdown	NN
cord-345879-nbfg47x5	114	21	thus	thus	RB
cord-345879-nbfg47x5	114	22	allowing	allow	VBG
cord-345879-nbfg47x5	114	23	peripheral	peripheral	JJ
cord-345879-nbfg47x5	114	24	cytokines	cytokine	NNS
cord-345879-nbfg47x5	114	25	to	to	TO
cord-345879-nbfg47x5	114	26	access	access	VB
cord-345879-nbfg47x5	114	27	to	to	IN
cord-345879-nbfg47x5	114	28	the	the	DT
cord-345879-nbfg47x5	114	29	CNS	CNS	NNP
cord-345879-nbfg47x5	114	30	where	where	WRB
cord-345879-nbfg47x5	114	31	they	-PRON-	PRP
cord-345879-nbfg47x5	114	32	may	may	MD
cord-345879-nbfg47x5	114	33	trigger	trigger	VB
cord-345879-nbfg47x5	114	34	or	or	CC
cord-345879-nbfg47x5	114	35	exacerbate	exacerbate	VB
cord-345879-nbfg47x5	114	36	neuroinflammation	neuroinflammation	NN
cord-345879-nbfg47x5	114	37	,	,	,
cord-345879-nbfg47x5	114	38	as	as	IN
cord-345879-nbfg47x5	114	39	reported	report	VBN
cord-345879-nbfg47x5	114	40	in	in	IN
cord-345879-nbfg47x5	114	41	experimental	experimental	JJ
cord-345879-nbfg47x5	114	42	model	model	NN
cord-345879-nbfg47x5	114	43	of	of	IN
cord-345879-nbfg47x5	114	44	postinfectious	postinfectious	NNP
cord-345879-nbfg47x5	114	45	autoimmune	autoimmune	NNP
cord-345879-nbfg47x5	114	46	encephalitis	encephalitis	NNP
cord-345879-nbfg47x5	114	47	(	(	-LRB-
cord-345879-nbfg47x5	114	48	Platt	Platt	NNP
cord-345879-nbfg47x5	114	49	et	et	NNP
cord-345879-nbfg47x5	114	50	al	al	NNP
cord-345879-nbfg47x5	114	51	.	.	NNP
cord-345879-nbfg47x5	114	52	2020	2020	CD
cord-345879-nbfg47x5	114	53	)	)	-RRB-
cord-345879-nbfg47x5	114	54	that	that	WDT
cord-345879-nbfg47x5	114	55	could	could	MD
cord-345879-nbfg47x5	114	56	contribute	contribute	VB
cord-345879-nbfg47x5	114	57	to	to	IN
cord-345879-nbfg47x5	114	58	neuroinflammatory	neuroinflammatory	NN
cord-345879-nbfg47x5	114	59	processes	process	NNS
cord-345879-nbfg47x5	114	60	and	and	CC
cord-345879-nbfg47x5	114	61	increase	increase	VB
cord-345879-nbfg47x5	114	62	susceptibility	susceptibility	NN
cord-345879-nbfg47x5	114	63	to	to	IN
cord-345879-nbfg47x5	114	64	neurological	neurological	JJ
cord-345879-nbfg47x5	114	65	syndromes	syndrome	NNS
cord-345879-nbfg47x5	114	66	.	.	.
cord-345879-nbfg47x5	115	1	In	in	IN
cord-345879-nbfg47x5	115	2	addition	addition	NN
cord-345879-nbfg47x5	115	3	,	,	,
cord-345879-nbfg47x5	115	4	olfactory	olfactory	JJ
cord-345879-nbfg47x5	115	5	tract	tract	NN
cord-345879-nbfg47x5	115	6	becomes	become	VBZ
cord-345879-nbfg47x5	115	7	an	an	DT
cord-345879-nbfg47x5	115	8	important	important	JJ
cord-345879-nbfg47x5	115	9	channel	channel	NN
cord-345879-nbfg47x5	115	10	for	for	IN
cord-345879-nbfg47x5	115	11	virus	virus	NN
cord-345879-nbfg47x5	115	12	transmission	transmission	NN
cord-345879-nbfg47x5	115	13	to	to	IN
cord-345879-nbfg47x5	115	14	brain	brain	NN
cord-345879-nbfg47x5	115	15	(	(	-LRB-
cord-345879-nbfg47x5	115	16	Mori	Mori	NNP
cord-345879-nbfg47x5	115	17	et	et	FW
cord-345879-nbfg47x5	115	18	al	al	NNP
cord-345879-nbfg47x5	115	19	.	.	NNP
cord-345879-nbfg47x5	115	20	2005	2005	CD
cord-345879-nbfg47x5	115	21	)	)	-RRB-
cord-345879-nbfg47x5	115	22	and	and	CC
cord-345879-nbfg47x5	115	23	anosmia	anosmia	NN
cord-345879-nbfg47x5	115	24	reported	report	VBD
cord-345879-nbfg47x5	115	25	in	in	IN
cord-345879-nbfg47x5	115	26	patients	patient	NNS
cord-345879-nbfg47x5	115	27	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	115	28	is	be	VBZ
cord-345879-nbfg47x5	115	29	possibly	possibly	RB
cord-345879-nbfg47x5	115	30	connected	connected	JJ
cord-345879-nbfg47x5	115	31	to	to	IN
cord-345879-nbfg47x5	115	32	the	the	DT
cord-345879-nbfg47x5	115	33	intranasal	intranasal	NN
cord-345879-nbfg47x5	115	34	route	route	NN
cord-345879-nbfg47x5	115	35	of	of	IN
cord-345879-nbfg47x5	115	36	infection	infection	NN
cord-345879-nbfg47x5	115	37	.	.	.
cord-345879-nbfg47x5	116	1	Coronavirus	Coronavirus	NNP
cord-345879-nbfg47x5	116	2	can	can	MD
cord-345879-nbfg47x5	116	3	invade	invade	VB
cord-345879-nbfg47x5	116	4	the	the	DT
cord-345879-nbfg47x5	116	5	CNS	CNS	NNP
cord-345879-nbfg47x5	116	6	from	from	IN
cord-345879-nbfg47x5	116	7	the	the	DT
cord-345879-nbfg47x5	116	8	periphery	periphery	NN
cord-345879-nbfg47x5	116	9	through	through	IN
cord-345879-nbfg47x5	116	10	neural	neural	JJ
cord-345879-nbfg47x5	116	11	pathways	pathway	NNS
cord-345879-nbfg47x5	116	12	)	)	-RRB-
cord-345879-nbfg47x5	116	13	.	.	.
cord-345879-nbfg47x5	117	1	In	in	IN
cord-345879-nbfg47x5	117	2	addition	addition	NN
cord-345879-nbfg47x5	117	3	,	,	,
cord-345879-nbfg47x5	117	4	the	the	DT
cord-345879-nbfg47x5	117	5	potential	potential	JJ
cord-345879-nbfg47x5	117	6	invasion	invasion	NN
cord-345879-nbfg47x5	117	7	to	to	IN
cord-345879-nbfg47x5	117	8	CNS	CNS	NNP
cord-345879-nbfg47x5	117	9	of	of	IN
cord-345879-nbfg47x5	117	10	SARS	SARS	NNP
cord-345879-nbfg47x5	117	11	-	-	HYPH
cord-345879-nbfg47x5	117	12	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	117	13	may	may	MD
cord-345879-nbfg47x5	117	14	be	be	VB
cord-345879-nbfg47x5	117	15	one	one	CD
cord-345879-nbfg47x5	117	16	reason	reason	NN
cord-345879-nbfg47x5	117	17	for	for	IN
cord-345879-nbfg47x5	117	18	the	the	DT
cord-345879-nbfg47x5	117	19	acute	acute	JJ
cord-345879-nbfg47x5	117	20	respiratory	respiratory	JJ
cord-345879-nbfg47x5	117	21	failure	failure	NN
cord-345879-nbfg47x5	117	22	.	.	.
cord-345879-nbfg47x5	118	1	Indeed	indeed	RB
cord-345879-nbfg47x5	118	2	,	,	,
cord-345879-nbfg47x5	118	3	some	some	DT
cord-345879-nbfg47x5	118	4	coronaviruses	coronaviruse	NNS
cord-345879-nbfg47x5	118	5	are	be	VBP
cord-345879-nbfg47x5	118	6	able	able	JJ
cord-345879-nbfg47x5	118	7	to	to	TO
cord-345879-nbfg47x5	118	8	spread	spread	VB
cord-345879-nbfg47x5	118	9	via	via	IN
cord-345879-nbfg47x5	118	10	a	a	DT
cord-345879-nbfg47x5	118	11	synapse	synapse	NN
cord-345879-nbfg47x5	118	12	-	-	HYPH
cord-345879-nbfg47x5	118	13	connected	connect	VBN
cord-345879-nbfg47x5	118	14	route	route	NN
cord-345879-nbfg47x5	118	15	to	to	IN
cord-345879-nbfg47x5	118	16	the	the	DT
cord-345879-nbfg47x5	118	17	medullary	medullary	JJ
cord-345879-nbfg47x5	118	18	cardiorespiratory	cardiorespiratory	JJ
cord-345879-nbfg47x5	118	19	centre	centre	NN
cord-345879-nbfg47x5	118	20	from	from	IN
cord-345879-nbfg47x5	118	21	the	the	DT
cord-345879-nbfg47x5	118	22	mechanoreceptors	mechanoreceptor	NNS
cord-345879-nbfg47x5	118	23	and	and	CC
cord-345879-nbfg47x5	118	24	chemoreceptors	chemoreceptor	NNS
cord-345879-nbfg47x5	118	25	in	in	IN
cord-345879-nbfg47x5	118	26	the	the	DT
cord-345879-nbfg47x5	118	27	lung	lung	NN
cord-345879-nbfg47x5	118	28	and	and	CC
cord-345879-nbfg47x5	118	29	lower	low	JJR
cord-345879-nbfg47x5	118	30	respiratory	respiratory	JJ
cord-345879-nbfg47x5	118	31	airways	airway	NNS
cord-345879-nbfg47x5	118	32	.	.	.
cord-345879-nbfg47x5	119	1	ACE2	ACE2	NNP
cord-345879-nbfg47x5	119	2	is	be	VBZ
cord-345879-nbfg47x5	119	3	expressed	express	VBN
cord-345879-nbfg47x5	119	4	in	in	IN
cord-345879-nbfg47x5	119	5	the	the	DT
cord-345879-nbfg47x5	119	6	nucleus	nucleus	NN
cord-345879-nbfg47x5	119	7	tractus	tractus	NN
cord-345879-nbfg47x5	119	8	solitarius	solitarius	NNP
cord-345879-nbfg47x5	119	9	and	and	CC
cord-345879-nbfg47x5	119	10	dorsal	dorsal	NNP
cord-345879-nbfg47x5	119	11	motor	motor	NN
cord-345879-nbfg47x5	119	12	nucleus	nucleus	NN
cord-345879-nbfg47x5	119	13	of	of	IN
cord-345879-nbfg47x5	119	14	the	the	DT
cord-345879-nbfg47x5	119	15	vagus	vagus	NN
cord-345879-nbfg47x5	119	16	nerve	nerve	NN
cord-345879-nbfg47x5	119	17	(	(	-LRB-
cord-345879-nbfg47x5	119	18	Doobay	Doobay	NNP
cord-345879-nbfg47x5	119	19	et	et	NNP
cord-345879-nbfg47x5	119	20	al	al	NNP
cord-345879-nbfg47x5	119	21	.	.	NNP
cord-345879-nbfg47x5	119	22	2007	2007	CD
cord-345879-nbfg47x5	119	23	)	)	-RRB-
cord-345879-nbfg47x5	119	24	.	.	.
cord-345879-nbfg47x5	120	1	Thus	thus	RB
cord-345879-nbfg47x5	120	2	,	,	,
cord-345879-nbfg47x5	120	3	the	the	DT
cord-345879-nbfg47x5	120	4	virus	virus	NN
cord-345879-nbfg47x5	120	5	might	may	MD
cord-345879-nbfg47x5	120	6	infect	infect	VB
cord-345879-nbfg47x5	120	7	the	the	DT
cord-345879-nbfg47x5	120	8	terminal	terminal	JJ
cord-345879-nbfg47x5	120	9	areas	area	NNS
cord-345879-nbfg47x5	120	10	of	of	IN
cord-345879-nbfg47x5	120	11	vagal	vagal	JJ
cord-345879-nbfg47x5	120	12	afferents	afferent	NNS
cord-345879-nbfg47x5	120	13	or	or	CC
cord-345879-nbfg47x5	120	14	the	the	DT
cord-345879-nbfg47x5	120	15	origin	origin	NN
cord-345879-nbfg47x5	120	16	of	of	IN
cord-345879-nbfg47x5	120	17	vagal	vagal	JJ
cord-345879-nbfg47x5	120	18	efferents	efferent	NNS
cord-345879-nbfg47x5	120	19	inducing	induce	VBG
cord-345879-nbfg47x5	120	20	down	down	IN
cord-345879-nbfg47x5	120	21	-	-	HYPH
cord-345879-nbfg47x5	120	22	regulation	regulation	NN
cord-345879-nbfg47x5	120	23	of	of	IN
cord-345879-nbfg47x5	120	24	ACE2	ACE2	NNP
cord-345879-nbfg47x5	120	25	and	and	CC
cord-345879-nbfg47x5	120	26	favouring	favour	VBG
cord-345879-nbfg47x5	120	27	local	local	JJ
cord-345879-nbfg47x5	120	28	inflammation	inflammation	NN
cord-345879-nbfg47x5	120	29	that	that	WDT
cord-345879-nbfg47x5	120	30	could	could	MD
cord-345879-nbfg47x5	120	31	disrupt	disrupt	VB
cord-345879-nbfg47x5	120	32	the	the	DT
cord-345879-nbfg47x5	120	33	CAP	cap	NN
cord-345879-nbfg47x5	120	34	and	and	CC
cord-345879-nbfg47x5	120	35	dysregulate	dysregulate	VB
cord-345879-nbfg47x5	120	36	the	the	DT
cord-345879-nbfg47x5	120	37	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	120	38	response	response	NN
cord-345879-nbfg47x5	120	39	.	.	.
cord-345879-nbfg47x5	121	1	Targeting	target	VBG
cord-345879-nbfg47x5	121	2	the	the	DT
cord-345879-nbfg47x5	121	3	CNS	CNS	NNP
cord-345879-nbfg47x5	121	4	with	with	IN
cord-345879-nbfg47x5	121	5	VNS	VNS	NNP
cord-345879-nbfg47x5	121	6	could	could	MD
cord-345879-nbfg47x5	121	7	have	have	VB
cord-345879-nbfg47x5	121	8	a	a	DT
cord-345879-nbfg47x5	121	9	protective	protective	JJ
cord-345879-nbfg47x5	121	10	effect	effect	NN
cord-345879-nbfg47x5	121	11	through	through	IN
cord-345879-nbfg47x5	121	12	a	a	DT
cord-345879-nbfg47x5	121	13	central	central	JJ
cord-345879-nbfg47x5	121	14	anti	anti	JJ
cord-345879-nbfg47x5	121	15	-	-	JJ
cord-345879-nbfg47x5	121	16	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	121	17	effect	effect	NN
cord-345879-nbfg47x5	121	18	.	.	.
cord-345879-nbfg47x5	122	1	Indeed	indeed	RB
cord-345879-nbfg47x5	122	2	,	,	,
cord-345879-nbfg47x5	122	3	VNS	VNS	NNP
cord-345879-nbfg47x5	122	4	significantly	significantly	RB
cord-345879-nbfg47x5	122	5	reduced	reduce	VBD
cord-345879-nbfg47x5	122	6	the	the	DT
cord-345879-nbfg47x5	122	7	central	central	JJ
cord-345879-nbfg47x5	122	8	levels	level	NNS
cord-345879-nbfg47x5	122	9	of	of	IN
cord-345879-nbfg47x5	122	10	proinflammatory	proinflammatory	JJ
cord-345879-nbfg47x5	122	11	cytokines	cytokine	NNS
cord-345879-nbfg47x5	122	12	and	and	CC
cord-345879-nbfg47x5	122	13	the	the	DT
cord-345879-nbfg47x5	122	14	percentage	percentage	NN
cord-345879-nbfg47x5	122	15	of	of	IN
cord-345879-nbfg47x5	122	16	microglia	microglia	NN
cord-345879-nbfg47x5	122	17	and	and	CC
cord-345879-nbfg47x5	122	18	macrophages	macrophage	NNS
cord-345879-nbfg47x5	122	19	in	in	IN
cord-345879-nbfg47x5	122	20	lipopolysaccharide	lipopolysaccharide	NN
cord-345879-nbfg47x5	122	21	stimulated	stimulate	VBD
cord-345879-nbfg47x5	122	22	mice	mouse	NNS
cord-345879-nbfg47x5	122	23	(	(	-LRB-
cord-345879-nbfg47x5	122	24	Meneses	Meneses	NNP
cord-345879-nbfg47x5	122	25	et	et	NNP
cord-345879-nbfg47x5	122	26	al	al	NNP
cord-345879-nbfg47x5	122	27	.	.	.
cord-345879-nbfg47x5	122	28	2016	2016	CD
cord-345879-nbfg47x5	122	29	)	)	-RRB-
cord-345879-nbfg47x5	122	30	.	.	.
cord-345879-nbfg47x5	123	1	Targeting	target	VBG
cord-345879-nbfg47x5	123	2	plasticity	plasticity	NN
cord-345879-nbfg47x5	123	3	with	with	IN
cord-345879-nbfg47x5	123	4	VNS	VNS	NNP
cord-345879-nbfg47x5	123	5	to	to	TO
cord-345879-nbfg47x5	123	6	renormalize	renormalize	VB
cord-345879-nbfg47x5	123	7	aberrant	aberrant	JJ
cord-345879-nbfg47x5	123	8	neural	neural	JJ
cord-345879-nbfg47x5	123	9	circuits	circuit	NNS
cord-345879-nbfg47x5	123	10	and	and	CC
cord-345879-nbfg47x5	123	11	restore	restore	VB
cord-345879-nbfg47x5	123	12	normal	normal	JJ
cord-345879-nbfg47x5	123	13	function	function	NN
cord-345879-nbfg47x5	123	14	is	be	VBZ
cord-345879-nbfg47x5	123	15	also	also	RB
cord-345879-nbfg47x5	123	16	of	of	IN
cord-345879-nbfg47x5	123	17	interest	interest	NN
cord-345879-nbfg47x5	124	1	(	(	-LRB-
cord-345879-nbfg47x5	124	2	Hays	Hays	NNP
cord-345879-nbfg47x5	124	3	et	et	NNP
cord-345879-nbfg47x5	124	4	al	al	NNP
cord-345879-nbfg47x5	124	5	.	.	NNP
cord-345879-nbfg47x5	124	6	2013	2013	CD
cord-345879-nbfg47x5	124	7	)	)	-RRB-
cord-345879-nbfg47x5	124	8	.	.	.
cord-345879-nbfg47x5	125	1	A	a	DT
cord-345879-nbfg47x5	125	2	vagus	vagus	NN
cord-345879-nbfg47x5	125	3	nerve	nerve	NN
cord-345879-nbfg47x5	125	4	-	-	HYPH
cord-345879-nbfg47x5	125	5	neurotrophin	neurotrophin	JJ
cord-345879-nbfg47x5	125	6	interaction	interaction	NN
cord-345879-nbfg47x5	125	7	model	model	NN
cord-345879-nbfg47x5	125	8	in	in	IN
cord-345879-nbfg47x5	125	9	the	the	DT
cord-345879-nbfg47x5	125	10	brain	brain	NN
cord-345879-nbfg47x5	125	11	has	have	VBZ
cord-345879-nbfg47x5	125	12	been	be	VBN
cord-345879-nbfg47x5	125	13	recently	recently	RB
cord-345879-nbfg47x5	125	14	proposed	propose	VBN
cord-345879-nbfg47x5	125	15	supporting	support	VBG
cord-345879-nbfg47x5	125	16	a	a	DT
cord-345879-nbfg47x5	125	17	putative	putative	JJ
cord-345879-nbfg47x5	125	18	role	role	NN
cord-345879-nbfg47x5	125	19	of	of	IN
cord-345879-nbfg47x5	125	20	Nerve	Nerve	NNP
cord-345879-nbfg47x5	125	21	Growth	Growth	NNP
cord-345879-nbfg47x5	125	22	Factor	Factor	NNP
cord-345879-nbfg47x5	125	23	and	and	CC
cord-345879-nbfg47x5	125	24	Brain	Brain	NNP
cord-345879-nbfg47x5	125	25	Derived	derive	VBD
cord-345879-nbfg47x5	125	26	Neurotrophic	Neurotrophic	NNP
cord-345879-nbfg47x5	125	27	Factor	Factor	NNP
cord-345879-nbfg47x5	125	28	in	in	IN
cord-345879-nbfg47x5	125	29	the	the	DT
cord-345879-nbfg47x5	125	30	mechanism	mechanism	NN
cord-345879-nbfg47x5	125	31	of	of	IN
cord-345879-nbfg47x5	125	32	action	action	NN
cord-345879-nbfg47x5	125	33	of	of	IN
cord-345879-nbfg47x5	125	34	VNS	VNS	NNP
cord-345879-nbfg47x5	125	35	to	to	TO
cord-345879-nbfg47x5	125	36	modulate	modulate	VB
cord-345879-nbfg47x5	125	37	brain	brain	NN
cord-345879-nbfg47x5	125	38	activities	activity	NNS
cord-345879-nbfg47x5	125	39	(	(	-LRB-
cord-345879-nbfg47x5	125	40	Rosso	Rosso	NNP
cord-345879-nbfg47x5	125	41	et	et	FW
cord-345879-nbfg47x5	125	42	al	al	NNP
cord-345879-nbfg47x5	125	43	.	.	NNP
cord-345879-nbfg47x5	125	44	2020	2020	CD
cord-345879-nbfg47x5	125	45	)	)	-RRB-
cord-345879-nbfg47x5	125	46	.	.	.
cord-345879-nbfg47x5	126	1	Vagal	vagal	JJ
cord-345879-nbfg47x5	126	2	tone	tone	NN
cord-345879-nbfg47x5	126	3	can	can	MD
cord-345879-nbfg47x5	126	4	be	be	VB
cord-345879-nbfg47x5	126	5	explored	explore	VBN
cord-345879-nbfg47x5	126	6	indirectly	indirectly	RB
cord-345879-nbfg47x5	126	7	and	and	CC
cord-345879-nbfg47x5	126	8	through	through	IN
cord-345879-nbfg47x5	126	9	a	a	DT
cord-345879-nbfg47x5	126	10	non	non	JJ
cord-345879-nbfg47x5	126	11	-	-	JJ
cord-345879-nbfg47x5	126	12	invasive	invasive	JJ
cord-345879-nbfg47x5	126	13	measure	measure	NN
cord-345879-nbfg47x5	126	14	namely	namely	RB
cord-345879-nbfg47x5	126	15	heart	heart	NN
cord-345879-nbfg47x5	126	16	rate	rate	NN
cord-345879-nbfg47x5	126	17	variability	variability	NN
cord-345879-nbfg47x5	126	18	.	.	.
cord-345879-nbfg47x5	127	1	Variations	variation	NNS
cord-345879-nbfg47x5	127	2	in	in	IN
cord-345879-nbfg47x5	127	3	the	the	DT
cord-345879-nbfg47x5	127	4	duration	duration	NN
cord-345879-nbfg47x5	127	5	of	of	IN
cord-345879-nbfg47x5	127	6	successive	successive	JJ
cord-345879-nbfg47x5	127	7	RR	rr	NN
cord-345879-nbfg47x5	127	8	intervals	interval	NNS
cord-345879-nbfg47x5	127	9	are	be	VBP
cord-345879-nbfg47x5	127	10	dependent	dependent	JJ
cord-345879-nbfg47x5	127	11	on	on	IN
cord-345879-nbfg47x5	127	12	the	the	DT
cord-345879-nbfg47x5	127	13	efferent	efferent	JJ
cord-345879-nbfg47x5	127	14	output	output	NN
cord-345879-nbfg47x5	127	15	of	of	IN
cord-345879-nbfg47x5	127	16	the	the	DT
cord-345879-nbfg47x5	127	17	sympathetic	sympathetic	JJ
cord-345879-nbfg47x5	127	18	and	and	CC
cord-345879-nbfg47x5	127	19	parasympathetic	parasympathetic	JJ
cord-345879-nbfg47x5	127	20	nerves	nerve	NNS
cord-345879-nbfg47x5	127	21	.	.	.
cord-345879-nbfg47x5	128	1	Under	under	IN
cord-345879-nbfg47x5	128	2	resting	rest	VBG
cord-345879-nbfg47x5	128	3	condition	condition	NN
cord-345879-nbfg47x5	128	4	,	,	,
cord-345879-nbfg47x5	128	5	this	this	DT
cord-345879-nbfg47x5	128	6	measure	measure	NN
cord-345879-nbfg47x5	128	7	reflects	reflect	VBZ
cord-345879-nbfg47x5	128	8	mainly	mainly	RB
cord-345879-nbfg47x5	128	9	the	the	DT
cord-345879-nbfg47x5	128	10	vagal	vagal	JJ
cord-345879-nbfg47x5	128	11	tone	tone	NN
cord-345879-nbfg47x5	128	12	on	on	IN
cord-345879-nbfg47x5	128	13	heart	heart	NN
cord-345879-nbfg47x5	128	14	rhythm	rhythm	NN
cord-345879-nbfg47x5	128	15	(	(	-LRB-
cord-345879-nbfg47x5	128	16	Heart	heart	NN
cord-345879-nbfg47x5	128	17	rate	rate	NN
cord-345879-nbfg47x5	128	18	variability	variability	NN
cord-345879-nbfg47x5	128	19	:	:	:
cord-345879-nbfg47x5	128	20	standards	standard	NNS
cord-345879-nbfg47x5	128	21	of	of	IN
cord-345879-nbfg47x5	128	22	measurement	measurement	NN
cord-345879-nbfg47x5	128	23	,	,	,
cord-345879-nbfg47x5	128	24	physiological	physiological	JJ
cord-345879-nbfg47x5	128	25	interpretation	interpretation	NN
cord-345879-nbfg47x5	128	26	and	and	CC
cord-345879-nbfg47x5	128	27	clinical	clinical	JJ
cord-345879-nbfg47x5	128	28	use	use	NN
cord-345879-nbfg47x5	128	29	1996	1996	CD
cord-345879-nbfg47x5	128	30	)	)	-RRB-
cord-345879-nbfg47x5	128	31	.	.	.
cord-345879-nbfg47x5	129	1	Vagal	vagal	JJ
cord-345879-nbfg47x5	129	2	tone	tone	NN
cord-345879-nbfg47x5	129	3	is	be	VBZ
cord-345879-nbfg47x5	129	4	dampened	dampen	VBN
cord-345879-nbfg47x5	129	5	in	in	IN
cord-345879-nbfg47x5	129	6	stress	stress	NN
cord-345879-nbfg47x5	129	7	condition	condition	NN
cord-345879-nbfg47x5	129	8	either	either	CC
cord-345879-nbfg47x5	129	9	of	of	IN
cord-345879-nbfg47x5	129	10	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	129	11	and/or	and/or	CC
cord-345879-nbfg47x5	129	12	infectious	infectious	JJ
cord-345879-nbfg47x5	129	13	origin	origin	NN
cord-345879-nbfg47x5	129	14	.	.	.
cord-345879-nbfg47x5	130	1	The	the	DT
cord-345879-nbfg47x5	130	2	level	level	NN
cord-345879-nbfg47x5	130	3	of	of	IN
cord-345879-nbfg47x5	130	4	resting	rest	VBG
cord-345879-nbfg47x5	130	5	vagal	vagal	JJ
cord-345879-nbfg47x5	130	6	tone	tone	NN
cord-345879-nbfg47x5	130	7	may	may	MD
cord-345879-nbfg47x5	130	8	give	give	VB
cord-345879-nbfg47x5	130	9	some	some	DT
cord-345879-nbfg47x5	130	10	indications	indication	NNS
cord-345879-nbfg47x5	130	11	about	about	IN
cord-345879-nbfg47x5	130	12	the	the	DT
cord-345879-nbfg47x5	130	13	individual	individual	JJ
cord-345879-nbfg47x5	130	14	vulnerability	vulnerability	NN
cord-345879-nbfg47x5	130	15	face	face	NN
cord-345879-nbfg47x5	130	16	to	to	IN
cord-345879-nbfg47x5	130	17	the	the	DT
cord-345879-nbfg47x5	130	18	stressors	stressor	NNS
cord-345879-nbfg47x5	130	19	(	(	-LRB-
cord-345879-nbfg47x5	130	20	i.e.	i.e.	FW
cord-345879-nbfg47x5	130	21	the	the	DT
cord-345879-nbfg47x5	130	22	virus	virus	NN
cord-345879-nbfg47x5	130	23	or	or	CC
cord-345879-nbfg47x5	130	24	inflammation	inflammation	NN
cord-345879-nbfg47x5	130	25	)	)	-RRB-
cord-345879-nbfg47x5	130	26	.	.	.
cord-345879-nbfg47x5	131	1	In	in	IN
cord-345879-nbfg47x5	131	2	particular	particular	JJ
cord-345879-nbfg47x5	131	3	,	,	,
cord-345879-nbfg47x5	131	4	we	-PRON-	PRP
cord-345879-nbfg47x5	131	5	have	have	VBP
cord-345879-nbfg47x5	131	6	shown	show	VBN
cord-345879-nbfg47x5	131	7	that	that	IN
cord-345879-nbfg47x5	131	8	in	in	IN
cord-345879-nbfg47x5	131	9	patients	patient	NNS
cord-345879-nbfg47x5	131	10	with	with	IN
cord-345879-nbfg47x5	131	11	Crohn	Crohn	NNP
cord-345879-nbfg47x5	131	12	's	's	POS
cord-345879-nbfg47x5	131	13	disease	disease	NN
cord-345879-nbfg47x5	131	14	in	in	IN
cord-345879-nbfg47x5	131	15	remission	remission	NN
cord-345879-nbfg47x5	131	16	,	,	,
cord-345879-nbfg47x5	131	17	there	there	EX
cord-345879-nbfg47x5	131	18	is	be	VBZ
cord-345879-nbfg47x5	131	19	an	an	DT
cord-345879-nbfg47x5	131	20	inverse	inverse	JJ
cord-345879-nbfg47x5	131	21	relation	relation	NN
cord-345879-nbfg47x5	131	22	between	between	IN
cord-345879-nbfg47x5	131	23	vagal	vagal	JJ
cord-345879-nbfg47x5	131	24	tone	tone	NN
cord-345879-nbfg47x5	131	25	and	and	CC
cord-345879-nbfg47x5	131	26	TNF	TNF	NNP
cord-345879-nbfg47x5	131	27	in	in	IN
cord-345879-nbfg47x5	131	28	the	the	DT
cord-345879-nbfg47x5	131	29	blood	blood	NN
cord-345879-nbfg47x5	131	30	(	(	-LRB-
cord-345879-nbfg47x5	131	31	Pellissier	Pellissier	NNP
cord-345879-nbfg47x5	131	32	et	et	NNP
cord-345879-nbfg47x5	131	33	al	al	NNP
cord-345879-nbfg47x5	131	34	.	.	NNP
cord-345879-nbfg47x5	131	35	2014	2014	CD
cord-345879-nbfg47x5	131	36	)	)	-RRB-
cord-345879-nbfg47x5	131	37	and	and	CC
cord-345879-nbfg47x5	131	38	that	that	IN
cord-345879-nbfg47x5	131	39	VNS	VNS	NNP
cord-345879-nbfg47x5	131	40	is	be	VBZ
cord-345879-nbfg47x5	131	41	able	able	JJ
cord-345879-nbfg47x5	131	42	to	to	TO
cord-345879-nbfg47x5	131	43	restore	restore	VB
cord-345879-nbfg47x5	131	44	vagal	vagal	JJ
cord-345879-nbfg47x5	131	45	tone	tone	NN
cord-345879-nbfg47x5	131	46	(	(	-LRB-
cord-345879-nbfg47x5	131	47	Bonaz	Bonaz	NNP
cord-345879-nbfg47x5	131	48	et	et	NNP
cord-345879-nbfg47x5	131	49	al	al	NNP
cord-345879-nbfg47x5	131	50	.	.	.
cord-345879-nbfg47x5	131	51	2016	2016	CD
cord-345879-nbfg47x5	131	52	;	;	:
cord-345879-nbfg47x5	131	53	Sinniger	Sinniger	NNP
cord-345879-nbfg47x5	131	54	et	et	NNP
cord-345879-nbfg47x5	131	55	al	al	NNP
cord-345879-nbfg47x5	131	56	.	.	NNP
cord-345879-nbfg47x5	131	57	2020	2020	CD
cord-345879-nbfg47x5	131	58	)	)	-RRB-
cord-345879-nbfg47x5	131	59	.	.	.
cord-345879-nbfg47x5	132	1	A	a	DT
cord-345879-nbfg47x5	132	2	lower	low	JJR
cord-345879-nbfg47x5	132	3	parasympathetic	parasympathetic	JJ
cord-345879-nbfg47x5	132	4	activity	activity	NN
cord-345879-nbfg47x5	132	5	and	and	CC
cord-345879-nbfg47x5	132	6	a	a	DT
cord-345879-nbfg47x5	132	7	decreased	decrease	VBN
cord-345879-nbfg47x5	132	8	expression	expression	NN
cord-345879-nbfg47x5	132	9	level	level	NN
cord-345879-nbfg47x5	132	10	of	of	IN
cord-345879-nbfg47x5	132	11	α7nAChR	α7nachr	NN
cord-345879-nbfg47x5	132	12	on	on	IN
cord-345879-nbfg47x5	132	13	peripheral	peripheral	JJ
cord-345879-nbfg47x5	132	14	blood	blood	NN
cord-345879-nbfg47x5	132	15	monocytes	monocyte	NNS
cord-345879-nbfg47x5	132	16	,	,	,
cord-345879-nbfg47x5	132	17	and	and	CC
cord-345879-nbfg47x5	132	18	higher	high	JJR
cord-345879-nbfg47x5	132	19	sympathetic	sympathetic	JJ
cord-345879-nbfg47x5	132	20	hormone	hormone	NN
cord-345879-nbfg47x5	132	21	(	(	-LRB-
cord-345879-nbfg47x5	132	22	norepinephrine	norepinephrine	NN
cord-345879-nbfg47x5	132	23	)	)	-RRB-
cord-345879-nbfg47x5	132	24	is	be	VBZ
cord-345879-nbfg47x5	132	25	observed	observe	VBN
cord-345879-nbfg47x5	132	26	in	in	IN
cord-345879-nbfg47x5	132	27	patients	patient	NNS
cord-345879-nbfg47x5	132	28	at	at	IN
cord-345879-nbfg47x5	132	29	risk	risk	NN
cord-345879-nbfg47x5	132	30	to	to	TO
cord-345879-nbfg47x5	132	31	develop	develop	VB
cord-345879-nbfg47x5	132	32	RA	RA	NNP
cord-345879-nbfg47x5	132	33	(	(	-LRB-
cord-345879-nbfg47x5	132	34	Koopman	Koopman	NNP
cord-345879-nbfg47x5	132	35	et	et	NNP
cord-345879-nbfg47x5	132	36	al	al	NNP
cord-345879-nbfg47x5	132	37	.	.	NNP
cord-345879-nbfg47x5	132	38	2016b	2016b	CD
cord-345879-nbfg47x5	132	39	)	)	-RRB-
cord-345879-nbfg47x5	132	40	.	.	.
cord-345879-nbfg47x5	133	1	Thus	thus	RB
cord-345879-nbfg47x5	133	2	,	,	,
cord-345879-nbfg47x5	133	3	a	a	DT
cord-345879-nbfg47x5	133	4	dysautonomia	dysautonomia	NN
cord-345879-nbfg47x5	133	5	precedes	precede	VBZ
cord-345879-nbfg47x5	133	6	the	the	DT
cord-345879-nbfg47x5	133	7	development	development	NN
cord-345879-nbfg47x5	133	8	of	of	IN
cord-345879-nbfg47x5	133	9	RA	RA	NNP
cord-345879-nbfg47x5	133	10	.	.	.
cord-345879-nbfg47x5	134	1	An	an	DT
cord-345879-nbfg47x5	134	2	autonomic	autonomic	JJ
cord-345879-nbfg47x5	134	3	dysfunction	dysfunction	NN
cord-345879-nbfg47x5	134	4	is	be	VBZ
cord-345879-nbfg47x5	134	5	reported	report	VBN
cord-345879-nbfg47x5	134	6	in	in	IN
cord-345879-nbfg47x5	134	7	various	various	JJ
cord-345879-nbfg47x5	134	8	pathological	pathological	JJ
cord-345879-nbfg47x5	134	9	conditions	condition	NNS
cord-345879-nbfg47x5	134	10	such	such	JJ
cord-345879-nbfg47x5	134	11	as	as	IN
cord-345879-nbfg47x5	134	12	obesity	obesity	NN
cord-345879-nbfg47x5	134	13	,	,	,
cord-345879-nbfg47x5	134	14	diabetes	diabetes	NN
cord-345879-nbfg47x5	134	15	,	,	,
cord-345879-nbfg47x5	134	16	hypertension	hypertension	NN
cord-345879-nbfg47x5	134	17	,	,	,
cord-345879-nbfg47x5	134	18	pulmonary	pulmonary	JJ
cord-345879-nbfg47x5	134	19	diseases	disease	NNS
cord-345879-nbfg47x5	134	20	(	(	-LRB-
cord-345879-nbfg47x5	134	21	Zalewski	Zalewski	NNP
cord-345879-nbfg47x5	134	22	et	et	NNP
cord-345879-nbfg47x5	134	23	al	al	NNP
cord-345879-nbfg47x5	134	24	.	.	.
cord-345879-nbfg47x5	134	25	2018	2018	CD
cord-345879-nbfg47x5	134	26	)	)	-RRB-
cord-345879-nbfg47x5	134	27	,	,	,
cord-345879-nbfg47x5	134	28	which	which	WDT
cord-345879-nbfg47x5	134	29	are	be	VBP
cord-345879-nbfg47x5	134	30	risk	risk	NN
cord-345879-nbfg47x5	134	31	factors	factor	NNS
cord-345879-nbfg47x5	134	32	for	for	IN
cord-345879-nbfg47x5	134	33	aggravating	aggravate	VBG
cord-345879-nbfg47x5	134	34	COVID-19	covid-19	JJ
cord-345879-nbfg47x5	134	35	infection	infection	NN
cord-345879-nbfg47x5	134	36	.	.	.
cord-345879-nbfg47x5	135	1	Monitoring	monitor	VBG
cord-345879-nbfg47x5	135	2	vagal	vagal	JJ
cord-345879-nbfg47x5	135	3	tone	tone	NN
cord-345879-nbfg47x5	135	4	in	in	IN
cord-345879-nbfg47x5	135	5	patients	patient	NNS
cord-345879-nbfg47x5	135	6	with	with	IN
cord-345879-nbfg47x5	135	7	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	135	8	could	could	MD
cord-345879-nbfg47x5	135	9	be	be	VB
cord-345879-nbfg47x5	135	10	of	of	IN
cord-345879-nbfg47x5	135	11	two	two	CD
cord-345879-nbfg47x5	135	12	major	major	JJ
cord-345879-nbfg47x5	135	13	interests	interest	NNS
cord-345879-nbfg47x5	135	14	.	.	.
cord-345879-nbfg47x5	136	1	Firstly	firstly	RB
cord-345879-nbfg47x5	136	2	,	,	,
cord-345879-nbfg47x5	136	3	it	-PRON-	PRP
cord-345879-nbfg47x5	136	4	can	can	MD
cord-345879-nbfg47x5	136	5	be	be	VB
cord-345879-nbfg47x5	136	6	a	a	DT
cord-345879-nbfg47x5	136	7	predictive	predictive	JJ
cord-345879-nbfg47x5	136	8	marker	marker	NN
cord-345879-nbfg47x5	136	9	of	of	IN
cord-345879-nbfg47x5	136	10	response	response	NN
cord-345879-nbfg47x5	136	11	to	to	IN
cord-345879-nbfg47x5	136	12	COVID	COVID	NNP
cord-345879-nbfg47x5	136	13	treatment	treatment	NN
cord-345879-nbfg47x5	136	14	such	such	JJ
cord-345879-nbfg47x5	136	15	as	as	IN
cord-345879-nbfg47x5	136	16	VNS	VNS	NNP
cord-345879-nbfg47x5	136	17	.	.	.
cord-345879-nbfg47x5	137	1	Secondly	secondly	RB
cord-345879-nbfg47x5	137	2	,	,	,
cord-345879-nbfg47x5	137	3	it	-PRON-	PRP
cord-345879-nbfg47x5	137	4	could	could	MD
cord-345879-nbfg47x5	137	5	be	be	VB
cord-345879-nbfg47x5	137	6	used	use	VBN
cord-345879-nbfg47x5	137	7	as	as	IN
cord-345879-nbfg47x5	137	8	a	a	DT
cord-345879-nbfg47x5	137	9	predictive	predictive	JJ
cord-345879-nbfg47x5	137	10	marker	marker	NN
cord-345879-nbfg47x5	137	11	of	of	IN
cord-345879-nbfg47x5	137	12	COVID	COVID	NNP
cord-345879-nbfg47x5	137	13	illness	illness	NN
cord-345879-nbfg47x5	137	14	course	course	NN
cord-345879-nbfg47x5	137	15	with	with	IN
cord-345879-nbfg47x5	137	16	the	the	DT
cord-345879-nbfg47x5	137	17	idea	idea	NN
cord-345879-nbfg47x5	137	18	that	that	IN
cord-345879-nbfg47x5	137	19	people	people	NNS
cord-345879-nbfg47x5	137	20	with	with	IN
cord-345879-nbfg47x5	137	21	very	very	RB
cord-345879-nbfg47x5	137	22	low	low	JJ
cord-345879-nbfg47x5	137	23	vagal	vagal	JJ
cord-345879-nbfg47x5	137	24	tone	tone	NN
cord-345879-nbfg47x5	137	25	at	at	IN
cord-345879-nbfg47x5	137	26	the	the	DT
cord-345879-nbfg47x5	137	27	onset	onset	NN
cord-345879-nbfg47x5	137	28	of	of	IN
cord-345879-nbfg47x5	137	29	the	the	DT
cord-345879-nbfg47x5	137	30	symptoms	symptom	NNS
cord-345879-nbfg47x5	137	31	may	may	MD
cord-345879-nbfg47x5	137	32	be	be	VB
cord-345879-nbfg47x5	137	33	at	at	IN
cord-345879-nbfg47x5	137	34	high	high	JJ
cord-345879-nbfg47x5	137	35	risk	risk	NN
cord-345879-nbfg47x5	137	36	to	to	TO
cord-345879-nbfg47x5	137	37	develop	develop	VB
cord-345879-nbfg47x5	137	38	a	a	DT
cord-345879-nbfg47x5	137	39	dysregulated	dysregulate	VBN
cord-345879-nbfg47x5	137	40	overstimulated	overstimulated	JJ
cord-345879-nbfg47x5	137	41	pro	pro	JJ
cord-345879-nbfg47x5	137	42	-	-	JJ
cord-345879-nbfg47x5	137	43	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	137	44	response	response	NN
cord-345879-nbfg47x5	137	45	during	during	IN
cord-345879-nbfg47x5	137	46	the	the	DT
cord-345879-nbfg47x5	137	47	infection	infection	NN
cord-345879-nbfg47x5	137	48	leading	lead	VBG
cord-345879-nbfg47x5	137	49	to	to	IN
cord-345879-nbfg47x5	137	50	sudden	sudden	JJ
cord-345879-nbfg47x5	137	51	death	death	NN
cord-345879-nbfg47x5	137	52	or	or	CC
cord-345879-nbfg47x5	137	53	intensive	intensive	JJ
cord-345879-nbfg47x5	137	54	care	care	NN
cord-345879-nbfg47x5	137	55	unit	unit	NN
cord-345879-nbfg47x5	137	56	transfer	transfer	NN
cord-345879-nbfg47x5	137	57	.	.	.
cord-345879-nbfg47x5	138	1	These	these	DT
cord-345879-nbfg47x5	138	2	patients	patient	NNS
cord-345879-nbfg47x5	138	3	could	could	MD
cord-345879-nbfg47x5	138	4	thus	thus	RB
cord-345879-nbfg47x5	138	5	benefit	benefit	VB
cord-345879-nbfg47x5	138	6	from	from	IN
cord-345879-nbfg47x5	138	7	VNS	VNS	NNP
cord-345879-nbfg47x5	138	8	.	.	.
cord-345879-nbfg47x5	139	1	Consequently	consequently	RB
cord-345879-nbfg47x5	139	2	,	,	,
cord-345879-nbfg47x5	139	3	both	both	DT
cord-345879-nbfg47x5	139	4	targeting	target	VBG
cord-345879-nbfg47x5	139	5	α7nAChR	α7nachr	CD
cord-345879-nbfg47x5	139	6	with	with	IN
cord-345879-nbfg47x5	139	7	VNS	VNS	NNP
cord-345879-nbfg47x5	139	8	and	and	CC
cord-345879-nbfg47x5	139	9	an	an	DT
cord-345879-nbfg47x5	139	10	early	early	JJ
cord-345879-nbfg47x5	139	11	continuous	continuous	JJ
cord-345879-nbfg47x5	139	12	monitoring	monitoring	NN
cord-345879-nbfg47x5	139	13	of	of	IN
cord-345879-nbfg47x5	139	14	vagal	vagal	JJ
cord-345879-nbfg47x5	139	15	tone	tone	NN
cord-345879-nbfg47x5	139	16	could	could	MD
cord-345879-nbfg47x5	139	17	be	be	VB
cord-345879-nbfg47x5	139	18	of	of	IN
cord-345879-nbfg47x5	139	19	interest	interest	NN
cord-345879-nbfg47x5	139	20	in	in	IN
cord-345879-nbfg47x5	139	21	the	the	DT
cord-345879-nbfg47x5	139	22	management	management	NN
cord-345879-nbfg47x5	139	23	of	of	IN
cord-345879-nbfg47x5	139	24	patients	patient	NNS
cord-345879-nbfg47x5	139	25	with	with	IN
cord-345879-nbfg47x5	139	26	COVID-19	covid-19	JJ
cord-345879-nbfg47x5	139	27	infection	infection	NN
cord-345879-nbfg47x5	139	28	.	.	.
cord-345879-nbfg47x5	140	1	VNS	VNS	NNP
cord-345879-nbfg47x5	140	2	is	be	VBZ
cord-345879-nbfg47x5	140	3	a	a	DT
cord-345879-nbfg47x5	140	4	slow	slow	RB
cord-345879-nbfg47x5	140	5	-	-	HYPH
cord-345879-nbfg47x5	140	6	acting	act	VBG
cord-345879-nbfg47x5	140	7	therapy	therapy	NN
cord-345879-nbfg47x5	140	8	,	,	,
cord-345879-nbfg47x5	140	9	as	as	IN
cord-345879-nbfg47x5	140	10	demonstrated	demonstrate	VBN
cord-345879-nbfg47x5	140	11	in	in	IN
cord-345879-nbfg47x5	140	12	epilepsy	epilepsy	NN
cord-345879-nbfg47x5	140	13	(	(	-LRB-
cord-345879-nbfg47x5	140	14	Elliott	Elliott	NNP
cord-345879-nbfg47x5	140	15	et	et	NNP
cord-345879-nbfg47x5	140	16	al	al	NNP
cord-345879-nbfg47x5	140	17	.	.	NNP
cord-345879-nbfg47x5	140	18	2011	2011	CD
cord-345879-nbfg47x5	140	19	)	)	-RRB-
cord-345879-nbfg47x5	140	20	and	and	CC
cord-345879-nbfg47x5	140	21	as	as	IN
cord-345879-nbfg47x5	140	22	we	-PRON-	PRP
cord-345879-nbfg47x5	140	23	have	have	VBP
cord-345879-nbfg47x5	140	24	observed	observe	VBN
cord-345879-nbfg47x5	140	25	in	in	IN
cord-345879-nbfg47x5	140	26	patients	patient	NNS
cord-345879-nbfg47x5	140	27	with	with	IN
cord-345879-nbfg47x5	140	28	Crohn	Crohn	NNP
cord-345879-nbfg47x5	140	29	's	's	POS
cord-345879-nbfg47x5	140	30	disease	disease	NN
cord-345879-nbfg47x5	140	31	since	since	IN
cord-345879-nbfg47x5	140	32	the	the	DT
cord-345879-nbfg47x5	140	33	delay	delay	NN
cord-345879-nbfg47x5	140	34	of	of	IN
cord-345879-nbfg47x5	140	35	onset	onset	NN
cord-345879-nbfg47x5	140	36	of	of	IN
cord-345879-nbfg47x5	140	37	action	action	NN
cord-345879-nbfg47x5	140	38	was~3	was~3	NNS
cord-345879-nbfg47x5	140	39	months	month	NNS
cord-345879-nbfg47x5	141	1	(	(	-LRB-
cord-345879-nbfg47x5	141	2	Bonaz	Bonaz	NNP
cord-345879-nbfg47x5	141	3	et	et	NNP
cord-345879-nbfg47x5	141	4	al	al	NNP
cord-345879-nbfg47x5	141	5	.	.	.
cord-345879-nbfg47x5	141	6	2016	2016	CD
cord-345879-nbfg47x5	142	1	;	;	:
cord-345879-nbfg47x5	142	2	Sinniger	Sinniger	NNP
cord-345879-nbfg47x5	142	3	et	et	NNP
cord-345879-nbfg47x5	142	4	al	al	NNP
cord-345879-nbfg47x5	142	5	.	.	NNP
cord-345879-nbfg47x5	142	6	2020	2020	CD
cord-345879-nbfg47x5	142	7	)	)	-RRB-
cord-345879-nbfg47x5	142	8	.	.	.
cord-345879-nbfg47x5	143	1	Consequently	consequently	RB
cord-345879-nbfg47x5	143	2	,	,	,
cord-345879-nbfg47x5	143	3	VNS	VNS	NNP
cord-345879-nbfg47x5	143	4	could	could	MD
cord-345879-nbfg47x5	143	5	be	be	VB
cord-345879-nbfg47x5	143	6	more	more	RBR
cord-345879-nbfg47x5	143	7	appropriate	appropriate	JJ
cord-345879-nbfg47x5	143	8	in	in	IN
cord-345879-nbfg47x5	143	9	moderate	moderate	JJ
cord-345879-nbfg47x5	143	10	forms	form	NNS
cord-345879-nbfg47x5	143	11	of	of	IN
cord-345879-nbfg47x5	143	12	the	the	DT
cord-345879-nbfg47x5	143	13	disease	disease	NN
cord-345879-nbfg47x5	143	14	and	and	CC
cord-345879-nbfg47x5	143	15	in	in	IN
cord-345879-nbfg47x5	143	16	the	the	DT
cord-345879-nbfg47x5	143	17	prevention	prevention	NN
cord-345879-nbfg47x5	143	18	of	of	IN
cord-345879-nbfg47x5	143	19	the	the	DT
cord-345879-nbfg47x5	143	20	cytokine	cytokine	NN
cord-345879-nbfg47x5	143	21	storm	storm	NN
cord-345879-nbfg47x5	143	22	in	in	IN
cord-345879-nbfg47x5	143	23	patients	patient	NNS
cord-345879-nbfg47x5	143	24	with	with	IN
cord-345879-nbfg47x5	143	25	low	low	JJ
cord-345879-nbfg47x5	143	26	vagal	vagal	JJ
cord-345879-nbfg47x5	143	27	tone	tone	NN
cord-345879-nbfg47x5	143	28	as	as	IN
cord-345879-nbfg47x5	143	29	indexed	index	VBN
cord-345879-nbfg47x5	143	30	by	by	IN
cord-345879-nbfg47x5	143	31	careful	careful	JJ
cord-345879-nbfg47x5	143	32	standard	standard	JJ
cord-345879-nbfg47x5	143	33	measures	measure	NNS
cord-345879-nbfg47x5	143	34	of	of	IN
cord-345879-nbfg47x5	143	35	heart	heart	NN
cord-345879-nbfg47x5	143	36	rate	rate	NN
cord-345879-nbfg47x5	143	37	variability	variability	NN
cord-345879-nbfg47x5	143	38	.	.	.
cord-345879-nbfg47x5	144	1	However	however	RB
cord-345879-nbfg47x5	144	2	,	,	,
cord-345879-nbfg47x5	144	3	SARS	SARS	NNP
cord-345879-nbfg47x5	144	4	-	-	HYPH
cord-345879-nbfg47x5	144	5	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	144	6	is	be	VBZ
cord-345879-nbfg47x5	144	7	a	a	DT
cord-345879-nbfg47x5	144	8	more	more	RBR
cord-345879-nbfg47x5	144	9	acute	acute	JJ
cord-345879-nbfg47x5	144	10	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	144	11	condition	condition	NN
cord-345879-nbfg47x5	144	12	,	,	,
cord-345879-nbfg47x5	144	13	especially	especially	RB
cord-345879-nbfg47x5	144	14	the	the	DT
cord-345879-nbfg47x5	144	15	cytokine	cytokine	NN
cord-345879-nbfg47x5	144	16	storm	storm	NN
cord-345879-nbfg47x5	144	17	,	,	,
cord-345879-nbfg47x5	144	18	than	than	IN
cord-345879-nbfg47x5	144	19	Crohn	Crohn	NNP
cord-345879-nbfg47x5	144	20	's	's	POS
cord-345879-nbfg47x5	144	21	disease	disease	NN
cord-345879-nbfg47x5	144	22	which	which	WDT
cord-345879-nbfg47x5	144	23	is	be	VBZ
cord-345879-nbfg47x5	144	24	a	a	DT
cord-345879-nbfg47x5	144	25	chronic	chronic	JJ
cord-345879-nbfg47x5	144	26	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	144	27	condition	condition	NN
cord-345879-nbfg47x5	144	28	.	.	.
cord-345879-nbfg47x5	145	1	Thus	thus	RB
cord-345879-nbfg47x5	145	2	,	,	,
cord-345879-nbfg47x5	145	3	one	one	PRP
cord-345879-nbfg47x5	145	4	can	can	MD
cord-345879-nbfg47x5	145	5	think	think	VB
cord-345879-nbfg47x5	145	6	that	that	IN
cord-345879-nbfg47x5	145	7	VNS	VNS	NNP
cord-345879-nbfg47x5	145	8	should	should	MD
cord-345879-nbfg47x5	145	9	be	be	VB
cord-345879-nbfg47x5	145	10	more	more	RBR
cord-345879-nbfg47x5	145	11	rapidly	rapidly	RB
cord-345879-nbfg47x5	145	12	active	active	JJ
cord-345879-nbfg47x5	145	13	as	as	IN
cord-345879-nbfg47x5	145	14	observed	observe	VBN
cord-345879-nbfg47x5	145	15	in	in	IN
cord-345879-nbfg47x5	145	16	acute	acute	JJ
cord-345879-nbfg47x5	145	17	inflammation	inflammation	NN
cord-345879-nbfg47x5	145	18	in	in	IN
cord-345879-nbfg47x5	145	19	models	model	NNS
cord-345879-nbfg47x5	145	20	of	of	IN
cord-345879-nbfg47x5	145	21	lipopolysaccharide	lipopolysaccharide	NN
cord-345879-nbfg47x5	145	22	-	-	HYPH
cord-345879-nbfg47x5	145	23	induced	induce	VBN
cord-345879-nbfg47x5	145	24	TNF	TNF	NNP
cord-345879-nbfg47x5	145	25	serum	serum	NN
cord-345879-nbfg47x5	145	26	levels	level	NNS
cord-345879-nbfg47x5	145	27	or	or	CC
cord-345879-nbfg47x5	145	28	postoperative	postoperative	JJ
cord-345879-nbfg47x5	145	29	ileus	ileus	NN
cord-345879-nbfg47x5	145	30	(	(	-LRB-
cord-345879-nbfg47x5	145	31	Stakenborg	Stakenborg	NNP
cord-345879-nbfg47x5	145	32	et	et	FW
cord-345879-nbfg47x5	145	33	al	al	NNP
cord-345879-nbfg47x5	145	34	.	.	.
cord-345879-nbfg47x5	145	35	2017	2017	CD
cord-345879-nbfg47x5	145	36	)	)	-RRB-
cord-345879-nbfg47x5	145	37	.	.	.
cord-345879-nbfg47x5	146	1	In	in	IN
cord-345879-nbfg47x5	146	2	addition	addition	NN
cord-345879-nbfg47x5	146	3	,	,	,
cord-345879-nbfg47x5	146	4	VNS	VNS	NNP
cord-345879-nbfg47x5	146	5	could	could	MD
cord-345879-nbfg47x5	146	6	accelerate	accelerate	VB
cord-345879-nbfg47x5	146	7	the	the	DT
cord-345879-nbfg47x5	146	8	post	post	JJ
cord-345879-nbfg47x5	146	9	-	-	JJ
cord-345879-nbfg47x5	146	10	COVID	covid	JJ
cord-345879-nbfg47x5	146	11	recovery	recovery	NN
cord-345879-nbfg47x5	146	12	and	and	CC
cord-345879-nbfg47x5	146	13	further	further	JJ
cord-345879-nbfg47x5	146	14	VNS	VNS	NNP
cord-345879-nbfg47x5	146	15	could	could	MD
cord-345879-nbfg47x5	146	16	reduce	reduce	VB
cord-345879-nbfg47x5	146	17	the	the	DT
cord-345879-nbfg47x5	146	18	posttraumatic	posttraumatic	JJ
cord-345879-nbfg47x5	146	19	stress	stress	NN
cord-345879-nbfg47x5	146	20	syndrome	syndrome	NN
cord-345879-nbfg47x5	146	21	classically	classically	RB
cord-345879-nbfg47x5	146	22	described	describe	VBN
cord-345879-nbfg47x5	146	23	in	in	IN
cord-345879-nbfg47x5	146	24	such	such	JJ
cord-345879-nbfg47x5	146	25	patients	patient	NNS
cord-345879-nbfg47x5	146	26	(	(	-LRB-
cord-345879-nbfg47x5	146	27	Xiao	Xiao	NNP
cord-345879-nbfg47x5	146	28	et	et	NNP
cord-345879-nbfg47x5	146	29	al	al	NNP
cord-345879-nbfg47x5	146	30	.	.	NNP
cord-345879-nbfg47x5	146	31	2020	2020	CD
cord-345879-nbfg47x5	146	32	)	)	-RRB-
cord-345879-nbfg47x5	146	33	.	.	.
cord-345879-nbfg47x5	147	1	Based	base	VBN
cord-345879-nbfg47x5	147	2	on	on	IN
cord-345879-nbfg47x5	147	3	the	the	DT
cord-345879-nbfg47x5	147	4	anti	anti	JJ
cord-345879-nbfg47x5	147	5	-	-	JJ
cord-345879-nbfg47x5	147	6	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	147	7	effects	effect	NNS
cord-345879-nbfg47x5	147	8	of	of	IN
cord-345879-nbfg47x5	147	9	VNS	VNS	NNP
cord-345879-nbfg47x5	147	10	both	both	CC
cord-345879-nbfg47x5	147	11	in	in	IN
cord-345879-nbfg47x5	147	12	the	the	DT
cord-345879-nbfg47x5	147	13	periphery	periphery	NN
cord-345879-nbfg47x5	147	14	and	and	CC
cord-345879-nbfg47x5	147	15	in	in	IN
cord-345879-nbfg47x5	147	16	the	the	DT
cord-345879-nbfg47x5	147	17	CNS	CNS	NNP
cord-345879-nbfg47x5	147	18	,	,	,
cord-345879-nbfg47x5	147	19	VNS	VNS	NNP
cord-345879-nbfg47x5	147	20	and	and	CC
cord-345879-nbfg47x5	147	21	continuous	continuous	JJ
cord-345879-nbfg47x5	147	22	monitoring	monitoring	NN
cord-345879-nbfg47x5	147	23	of	of	IN
cord-345879-nbfg47x5	147	24	vagal	vagal	JJ
cord-345879-nbfg47x5	147	25	tone	tone	NN
cord-345879-nbfg47x5	147	26	through	through	IN
cord-345879-nbfg47x5	147	27	heart	heart	NN
cord-345879-nbfg47x5	147	28	rate	rate	NN
cord-345879-nbfg47x5	147	29	variability	variability	NN
cord-345879-nbfg47x5	147	30	appears	appear	VBZ
cord-345879-nbfg47x5	147	31	as	as	IN
cord-345879-nbfg47x5	147	32	two	two	CD
cord-345879-nbfg47x5	147	33	particularly	particularly	RB
cord-345879-nbfg47x5	147	34	innovative	innovative	JJ
cord-345879-nbfg47x5	147	35	applications	application	NNS
cord-345879-nbfg47x5	147	36	in	in	IN
cord-345879-nbfg47x5	147	37	COVID-19	covid-19	JJ
cord-345879-nbfg47x5	147	38	patient	patient	JJ
cord-345879-nbfg47x5	147	39	management	management	NN
cord-345879-nbfg47x5	147	40	.	.	.
cord-345879-nbfg47x5	147	41	 	 	_SP
cord-345879-nbfg47x5	148	1	Prevalence	prevalence	NN
cord-345879-nbfg47x5	148	2	,	,	,
cord-345879-nbfg47x5	148	3	severity	severity	NN
cord-345879-nbfg47x5	148	4	and	and	CC
cord-345879-nbfg47x5	148	5	mortality	mortality	NN
cord-345879-nbfg47x5	148	6	associated	associate	VBN
cord-345879-nbfg47x5	148	7	with	with	IN
cord-345879-nbfg47x5	148	8	COPD	COPD	NNP
cord-345879-nbfg47x5	148	9	and	and	CC
cord-345879-nbfg47x5	148	10	smoking	smoking	NN
cord-345879-nbfg47x5	148	11	in	in	IN
cord-345879-nbfg47x5	148	12	patients	patient	NNS
cord-345879-nbfg47x5	148	13	with	with	IN
cord-345879-nbfg47x5	148	14	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	148	15	:	:	:
cord-345879-nbfg47x5	148	16	a	a	DT
cord-345879-nbfg47x5	148	17	rapid	rapid	JJ
cord-345879-nbfg47x5	148	18	systematic	systematic	JJ
cord-345879-nbfg47x5	148	19	review	review	NN
cord-345879-nbfg47x5	148	20	and	and	CC
cord-345879-nbfg47x5	148	21	meta	meta	NNP
cord-345879-nbfg47x5	148	22	-	-	HYPH
cord-345879-nbfg47x5	148	23	analysis	analysis	NN
cord-345879-nbfg47x5	149	1	The	the	DT
cord-345879-nbfg47x5	149	2	central	central	JJ
cord-345879-nbfg47x5	149	3	autonomic	autonomic	JJ
cord-345879-nbfg47x5	149	4	network	network	NN
cord-345879-nbfg47x5	149	5	:	:	:
cord-345879-nbfg47x5	149	6	functional	functional	JJ
cord-345879-nbfg47x5	149	7	organization	organization	NN
cord-345879-nbfg47x5	149	8	,	,	,
cord-345879-nbfg47x5	149	9	dysfunction	dysfunction	NN
cord-345879-nbfg47x5	149	10	,	,	,
cord-345879-nbfg47x5	149	11	and	and	CC
cord-345879-nbfg47x5	149	12	perspective	perspective	NN
cord-345879-nbfg47x5	149	13	Impact	impact	NN
cord-345879-nbfg47x5	149	14	of	of	IN
cord-345879-nbfg47x5	149	15	cigarette	cigarette	NN
cord-345879-nbfg47x5	149	16	smoking	smoking	NN
cord-345879-nbfg47x5	149	17	on	on	IN
cord-345879-nbfg47x5	149	18	the	the	DT
cord-345879-nbfg47x5	149	19	gastrointestinal	gastrointestinal	JJ
cord-345879-nbfg47x5	149	20	tract	tract	NN
cord-345879-nbfg47x5	149	21	inflammation	inflammation	NN
cord-345879-nbfg47x5	149	22	:	:	:
cord-345879-nbfg47x5	149	23	opposing	oppose	VBG
cord-345879-nbfg47x5	149	24	effects	effect	NNS
cord-345879-nbfg47x5	149	25	in	in	IN
cord-345879-nbfg47x5	149	26	Crohn	Crohn	NNP
cord-345879-nbfg47x5	149	27	's	's	POS
cord-345879-nbfg47x5	149	28	disease	disease	NN
cord-345879-nbfg47x5	149	29	and	and	CC
cord-345879-nbfg47x5	149	30	ulcerative	ulcerative	JJ
cord-345879-nbfg47x5	149	31	colitis	colitis	NN
cord-345879-nbfg47x5	149	32	Outcomes	Outcomes	NNPS
cord-345879-nbfg47x5	149	33	of	of	IN
cord-345879-nbfg47x5	149	34	COVID-19	covid-19	VBP
cord-345879-nbfg47x5	149	35	in	in	IN
cord-345879-nbfg47x5	149	36	79	79	CD
cord-345879-nbfg47x5	149	37	patients	patient	NNS
cord-345879-nbfg47x5	149	38	with	with	IN
cord-345879-nbfg47x5	149	39	IBD	IBD	NNP
cord-345879-nbfg47x5	149	40	in	in	IN
cord-345879-nbfg47x5	149	41	Italy	Italy	NNP
cord-345879-nbfg47x5	149	42	:	:	:
cord-345879-nbfg47x5	149	43	an	an	DT
cord-345879-nbfg47x5	149	44	IG	IG	NNP
cord-345879-nbfg47x5	149	45	-	-	HYPH
cord-345879-nbfg47x5	149	46	IBD	IBD	NNP
cord-345879-nbfg47x5	149	47	study	study	NN
cord-345879-nbfg47x5	149	48	Chronic	Chronic	NNP
cord-345879-nbfg47x5	149	49	vagus	vagus	NN
cord-345879-nbfg47x5	149	50	nerve	nerve	NN
cord-345879-nbfg47x5	149	51	stimulation	stimulation	NN
cord-345879-nbfg47x5	149	52	in	in	IN
cord-345879-nbfg47x5	149	53	Crohn	Crohn	NNP
cord-345879-nbfg47x5	149	54	's	's	POS
cord-345879-nbfg47x5	149	55	disease	disease	NN
cord-345879-nbfg47x5	149	56	:	:	:
cord-345879-nbfg47x5	149	57	a	a	DT
cord-345879-nbfg47x5	149	58	6-month	6-month	CD
cord-345879-nbfg47x5	149	59	follow	follow	NN
cord-345879-nbfg47x5	149	60	-	-	HYPH
cord-345879-nbfg47x5	149	61	up	up	RP
cord-345879-nbfg47x5	149	62	pilot	pilot	NN
cord-345879-nbfg47x5	149	63	study	study	NN
cord-345879-nbfg47x5	149	64	vagus	vagus	NN
cord-345879-nbfg47x5	149	65	Nerve	nerve	NN
cord-345879-nbfg47x5	149	66	Stimulation	stimulation	NN
cord-345879-nbfg47x5	149	67	at	at	IN
cord-345879-nbfg47x5	149	68	the	the	DT
cord-345879-nbfg47x5	149	69	Interface	Interface	NNP
cord-345879-nbfg47x5	149	70	of	of	IN
cord-345879-nbfg47x5	149	71	Brain	Brain	NNP
cord-345879-nbfg47x5	149	72	-	-	HYPH
cord-345879-nbfg47x5	149	73	Gut	Gut	NNP
cord-345879-nbfg47x5	149	74	Interactions	Interactions	NNPS
cord-345879-nbfg47x5	149	75	Neurostimulation	Neurostimulation	NNP
cord-345879-nbfg47x5	149	76	for	for	IN
cord-345879-nbfg47x5	149	77	drug	drug	NN
cord-345879-nbfg47x5	149	78	-	-	HYPH
cord-345879-nbfg47x5	149	79	resistant	resistant	JJ
cord-345879-nbfg47x5	149	80	epilepsy	epilepsy	NN
cord-345879-nbfg47x5	149	81	:	:	:
cord-345879-nbfg47x5	149	82	a	a	DT
cord-345879-nbfg47x5	149	83	systematic	systematic	JJ
cord-345879-nbfg47x5	149	84	review	review	NN
cord-345879-nbfg47x5	149	85	of	of	IN
cord-345879-nbfg47x5	149	86	clinical	clinical	JJ
cord-345879-nbfg47x5	149	87	evidence	evidence	NN
cord-345879-nbfg47x5	149	88	for	for	IN
cord-345879-nbfg47x5	149	89	efficacy	efficacy	NN
cord-345879-nbfg47x5	149	90	,	,	,
cord-345879-nbfg47x5	149	91	safety	safety	NN
cord-345879-nbfg47x5	149	92	,	,	,
cord-345879-nbfg47x5	149	93	contraindications	contraindication	NNS
cord-345879-nbfg47x5	149	94	and	and	CC
cord-345879-nbfg47x5	149	95	predictors	predictor	NNS
cord-345879-nbfg47x5	149	96	for	for	IN
cord-345879-nbfg47x5	149	97	response	response	NN
cord-345879-nbfg47x5	149	98	Role	role	NN
cord-345879-nbfg47x5	149	99	of	of	IN
cord-345879-nbfg47x5	149	100	vagus	vagus	NN
cord-345879-nbfg47x5	149	101	nerve	nerve	NN
cord-345879-nbfg47x5	149	102	signaling	signal	VBG
cord-345879-nbfg47x5	149	103	in	in	IN
cord-345879-nbfg47x5	149	104	CNI-1493-mediated	cni-1493-mediated	JJ
cord-345879-nbfg47x5	149	105	suppression	suppression	NN
cord-345879-nbfg47x5	149	106	of	of	IN
cord-345879-nbfg47x5	149	107	acute	acute	JJ
cord-345879-nbfg47x5	149	108	inflammation	inflammation	NN
cord-345879-nbfg47x5	150	1	A	a	DT
cord-345879-nbfg47x5	150	2	nicotinic	nicotinic	JJ
cord-345879-nbfg47x5	150	3	hypothesis	hypothesis	NN
cord-345879-nbfg47x5	150	4	for	for	IN
cord-345879-nbfg47x5	150	5	Covid-19	Covid-19	NNP
cord-345879-nbfg47x5	150	6	with	with	IN
cord-345879-nbfg47x5	150	7	preventive	preventive	JJ
cord-345879-nbfg47x5	150	8	and	and	CC
cord-345879-nbfg47x5	150	9	therapeutic	therapeutic	JJ
cord-345879-nbfg47x5	150	10	implications	implication	NNS
cord-345879-nbfg47x5	151	1	Stimulation	stimulation	NN
cord-345879-nbfg47x5	151	2	of	of	IN
cord-345879-nbfg47x5	151	3	the	the	DT
cord-345879-nbfg47x5	151	4	vagus	vagus	NN
cord-345879-nbfg47x5	151	5	nerve	nerve	NN
cord-345879-nbfg47x5	151	6	attenuates	attenuate	VBZ
cord-345879-nbfg47x5	151	7	macrophage	macrophage	NN
cord-345879-nbfg47x5	151	8	activation	activation	NN
cord-345879-nbfg47x5	151	9	by	by	IN
cord-345879-nbfg47x5	151	10	activating	activate	VBG
cord-345879-nbfg47x5	151	11	the	the	DT
cord-345879-nbfg47x5	151	12	Jak2-STAT3	Jak2-STAT3	NNP
cord-345879-nbfg47x5	151	13	signaling	signal	VBG
cord-345879-nbfg47x5	151	14	pathway	pathway	NN
cord-345879-nbfg47x5	151	15	Differential	differential	JJ
cord-345879-nbfg47x5	151	16	expression	expression	NN
cord-345879-nbfg47x5	151	17	of	of	IN
cord-345879-nbfg47x5	151	18	neuronal	neuronal	JJ
cord-345879-nbfg47x5	151	19	ACE2	ACE2	NNP
cord-345879-nbfg47x5	151	20	in	in	IN
cord-345879-nbfg47x5	151	21	transgenic	transgenic	JJ
cord-345879-nbfg47x5	151	22	mice	mouse	NNS
cord-345879-nbfg47x5	151	23	with	with	IN
cord-345879-nbfg47x5	151	24	overexpression	overexpression	NN
cord-345879-nbfg47x5	151	25	of	of	IN
cord-345879-nbfg47x5	151	26	the	the	DT
cord-345879-nbfg47x5	151	27	brain	brain	NN
cord-345879-nbfg47x5	151	28	renin	renin	NN
cord-345879-nbfg47x5	151	29	-	-	HYPH
cord-345879-nbfg47x5	151	30	angiotensin	angiotensin	NN
cord-345879-nbfg47x5	151	31	system	system	NN
cord-345879-nbfg47x5	152	1	Neuroimmune	Neuroimmune	NNP
cord-345879-nbfg47x5	152	2	regulation	regulation	NN
cord-345879-nbfg47x5	152	3	of	of	IN
cord-345879-nbfg47x5	152	4	ventilator	ventilator	NN
cord-345879-nbfg47x5	152	5	-	-	HYPH
cord-345879-nbfg47x5	152	6	induced	induce	VBN
cord-345879-nbfg47x5	152	7	lung	lung	NN
cord-345879-nbfg47x5	152	8	injury	injury	NN
cord-345879-nbfg47x5	152	9	Faecal	Faecal	NNP
cord-345879-nbfg47x5	152	10	calprotectin	calprotectin	NNP
cord-345879-nbfg47x5	152	11	indicates	indicate	VBZ
cord-345879-nbfg47x5	152	12	intestinal	intestinal	JJ
cord-345879-nbfg47x5	152	13	inflammation	inflammation	NN
cord-345879-nbfg47x5	152	14	in	in	IN
cord-345879-nbfg47x5	152	15	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	152	16	Efficacy	Efficacy	NNP
cord-345879-nbfg47x5	152	17	of	of	IN
cord-345879-nbfg47x5	152	18	vagus	vagus	JJ
cord-345879-nbfg47x5	152	19	nerve	nerve	NN
cord-345879-nbfg47x5	152	20	stimulation	stimulation	NN
cord-345879-nbfg47x5	152	21	over	over	IN
cord-345879-nbfg47x5	152	22	time	time	NN
cord-345879-nbfg47x5	152	23	:	:	:
cord-345879-nbfg47x5	152	24	review	review	NN
cord-345879-nbfg47x5	152	25	of	of	IN
cord-345879-nbfg47x5	152	26	65	65	CD
cord-345879-nbfg47x5	152	27	consecutive	consecutive	JJ
cord-345879-nbfg47x5	152	28	patients	patient	NNS
cord-345879-nbfg47x5	152	29	with	with	IN
cord-345879-nbfg47x5	152	30	treatment	treatment	NN
cord-345879-nbfg47x5	152	31	-	-	HYPH
cord-345879-nbfg47x5	152	32	resistant	resistant	JJ
cord-345879-nbfg47x5	152	33	epilepsy	epilepsy	NN
cord-345879-nbfg47x5	152	34	treated	treat	VBN
cord-345879-nbfg47x5	152	35	with	with	IN
cord-345879-nbfg47x5	152	36	VNS	VNS	NNP
cord-345879-nbfg47x5	152	37	>	>	XX
cord-345879-nbfg47x5	152	38	10	10	CD
cord-345879-nbfg47x5	152	39	years	year	NNS
cord-345879-nbfg47x5	152	40	Systematic	systematic	JJ
cord-345879-nbfg47x5	152	41	review	review	NN
cord-345879-nbfg47x5	152	42	of	of	IN
cord-345879-nbfg47x5	152	43	the	the	DT
cord-345879-nbfg47x5	152	44	prevalence	prevalence	NN
cord-345879-nbfg47x5	152	45	of	of	IN
cord-345879-nbfg47x5	152	46	current	current	JJ
cord-345879-nbfg47x5	152	47	smoking	smoking	NN
cord-345879-nbfg47x5	152	48	among	among	IN
cord-345879-nbfg47x5	152	49	hospitalized	hospitalize	VBN
cord-345879-nbfg47x5	152	50	COVID-19	covid-19	CD
cord-345879-nbfg47x5	152	51	patients	patient	NNS
cord-345879-nbfg47x5	152	52	in	in	IN
cord-345879-nbfg47x5	152	53	China	China	NNP
cord-345879-nbfg47x5	152	54	:	:	:
cord-345879-nbfg47x5	152	55	could	could	MD
cord-345879-nbfg47x5	152	56	nicotine	nicotine	NN
cord-345879-nbfg47x5	152	57	be	be	VB
cord-345879-nbfg47x5	152	58	a	a	DT
cord-345879-nbfg47x5	152	59	therapeutic	therapeutic	JJ
cord-345879-nbfg47x5	152	60	option	option	NN
cord-345879-nbfg47x5	152	61	?	?	.
cord-345879-nbfg47x5	153	1	Intern	Intern	NNP
cord-345879-nbfg47x5	153	2	Emerg	Emerg	NNP
cord-345879-nbfg47x5	153	3	med	med	NNP
cord-345879-nbfg47x5	153	4	Editorial	editorial	NN
cord-345879-nbfg47x5	153	5	:	:	:
cord-345879-nbfg47x5	153	6	nicotine	nicotine	NN
cord-345879-nbfg47x5	153	7	and	and	CC
cord-345879-nbfg47x5	153	8	SARS	SARS	NNP
cord-345879-nbfg47x5	153	9	-	-	HYPH
cord-345879-nbfg47x5	153	10	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	153	11	:	:	:
cord-345879-nbfg47x5	154	1	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	154	2	may	may	MD
cord-345879-nbfg47x5	154	3	be	be	VB
cord-345879-nbfg47x5	154	4	a	a	DT
cord-345879-nbfg47x5	154	5	disease	disease	NN
cord-345879-nbfg47x5	154	6	of	of	IN
cord-345879-nbfg47x5	154	7	the	the	DT
cord-345879-nbfg47x5	154	8	nicotinic	nicotinic	JJ
cord-345879-nbfg47x5	154	9	cholinergic	cholinergic	JJ
cord-345879-nbfg47x5	154	10	system	system	NN
cord-345879-nbfg47x5	154	11	Innervation	Innervation	NNP
cord-345879-nbfg47x5	154	12	of	of	IN
cord-345879-nbfg47x5	154	13	alveolar	alveolar	JJ
cord-345879-nbfg47x5	154	14	walls	wall	NNS
cord-345879-nbfg47x5	154	15	in	in	IN
cord-345879-nbfg47x5	154	16	the	the	DT
cord-345879-nbfg47x5	154	17	human	human	JJ
cord-345879-nbfg47x5	154	18	lung	lung	NN
cord-345879-nbfg47x5	154	19	:	:	:
cord-345879-nbfg47x5	154	20	an	an	DT
cord-345879-nbfg47x5	154	21	electron	electron	NN
cord-345879-nbfg47x5	154	22	microscopic	microscopic	JJ
cord-345879-nbfg47x5	154	23	study	study	NN
cord-345879-nbfg47x5	154	24	Expression	expression	NN
cord-345879-nbfg47x5	154	25	and	and	CC
cord-345879-nbfg47x5	154	26	function	function	NN
cord-345879-nbfg47x5	154	27	of	of	IN
cord-345879-nbfg47x5	154	28	the	the	DT
cord-345879-nbfg47x5	154	29	cholinergic	cholinergic	JJ
cord-345879-nbfg47x5	154	30	system	system	NN
cord-345879-nbfg47x5	154	31	in	in	IN
cord-345879-nbfg47x5	154	32	immune	immune	JJ
cord-345879-nbfg47x5	154	33	cells	cell	NNS
cord-345879-nbfg47x5	154	34	Covid-19	covid-19	VBP
cord-345879-nbfg47x5	154	35	in	in	IN
cord-345879-nbfg47x5	154	36	immune	immune	NN
cord-345879-nbfg47x5	154	37	-	-	HYPH
cord-345879-nbfg47x5	154	38	mediated	mediate	VBN
cord-345879-nbfg47x5	154	39	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	154	40	diseases	disease	NNS
cord-345879-nbfg47x5	155	1	-case	-case	NNP
cord-345879-nbfg47x5	155	2	series	series	NNP
cord-345879-nbfg47x5	155	3	from	from	IN
cord-345879-nbfg47x5	155	4	New	New	NNP
cord-345879-nbfg47x5	155	5	York	York	NNP
cord-345879-nbfg47x5	155	6	Heart	Heart	NNP
cord-345879-nbfg47x5	155	7	rate	rate	NN
cord-345879-nbfg47x5	155	8	variability	variability	NN
cord-345879-nbfg47x5	155	9	:	:	:
cord-345879-nbfg47x5	155	10	standards	standard	NNS
cord-345879-nbfg47x5	155	11	of	of	IN
cord-345879-nbfg47x5	155	12	measurement	measurement	NN
cord-345879-nbfg47x5	155	13	,	,	,
cord-345879-nbfg47x5	155	14	physiological	physiological	JJ
cord-345879-nbfg47x5	155	15	interpretation	interpretation	NN
cord-345879-nbfg47x5	155	16	and	and	CC
cord-345879-nbfg47x5	155	17	clinical	clinical	JJ
cord-345879-nbfg47x5	155	18	use	use	NN
cord-345879-nbfg47x5	155	19	.	.	.
cord-345879-nbfg47x5	156	1	Task	task	NN
cord-345879-nbfg47x5	156	2	force	force	NN
cord-345879-nbfg47x5	156	3	of	of	IN
cord-345879-nbfg47x5	156	4	the	the	DT
cord-345879-nbfg47x5	156	5	European	European	NNP
cord-345879-nbfg47x5	156	6	Society	Society	NNP
cord-345879-nbfg47x5	156	7	of	of	IN
cord-345879-nbfg47x5	156	8	Cardiology	Cardiology	NNP
cord-345879-nbfg47x5	156	9	and	and	CC
cord-345879-nbfg47x5	156	10	the	the	DT
cord-345879-nbfg47x5	156	11	north	north	JJ
cord-345879-nbfg47x5	156	12	American	American	NNP
cord-345879-nbfg47x5	156	13	Society	Society	NNP
cord-345879-nbfg47x5	156	14	of	of	IN
cord-345879-nbfg47x5	156	15	Pacing	Pacing	NNP
cord-345879-nbfg47x5	156	16	and	and	CC
cord-345879-nbfg47x5	156	17	Electrophysiology	Electrophysiology	NNP
cord-345879-nbfg47x5	156	18	SARS	SARS	NNP
cord-345879-nbfg47x5	156	19	-	-	HYPH
cord-345879-nbfg47x5	156	20	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	156	21	cell	cell	NN
cord-345879-nbfg47x5	156	22	entry	entry	NN
cord-345879-nbfg47x5	156	23	depends	depend	VBZ
cord-345879-nbfg47x5	156	24	on	on	IN
cord-345879-nbfg47x5	156	25	ACE2	ACE2	NNP
cord-345879-nbfg47x5	156	26	and	and	CC
cord-345879-nbfg47x5	156	27	TMPRSS2	TMPRSS2	NNP
cord-345879-nbfg47x5	156	28	and	and	CC
cord-345879-nbfg47x5	156	29	is	be	VBZ
cord-345879-nbfg47x5	156	30	blocked	block	VBN
cord-345879-nbfg47x5	156	31	by	by	IN
cord-345879-nbfg47x5	156	32	a	a	DT
cord-345879-nbfg47x5	156	33	clinically	clinically	RB
cord-345879-nbfg47x5	156	34	proven	prove	VBN
cord-345879-nbfg47x5	156	35	protease	protease	NN
cord-345879-nbfg47x5	156	36	inhibitor	inhibitor	NN
cord-345879-nbfg47x5	156	37	Mining	Mining	NNP
cord-345879-nbfg47x5	156	38	the	the	DT
cord-345879-nbfg47x5	156	39	characteristics	characteristic	NNS
cord-345879-nbfg47x5	156	40	of	of	IN
cord-345879-nbfg47x5	156	41	COVID-19	covid-19	JJ
cord-345879-nbfg47x5	156	42	patients	patient	NNS
cord-345879-nbfg47x5	156	43	in	in	IN
cord-345879-nbfg47x5	156	44	China	China	NNP
cord-345879-nbfg47x5	156	45	:	:	:
cord-345879-nbfg47x5	156	46	analysis	analysis	NN
cord-345879-nbfg47x5	156	47	of	of	IN
cord-345879-nbfg47x5	156	48	social	social	JJ
cord-345879-nbfg47x5	156	49	media	medium	NNS
cord-345879-nbfg47x5	156	50	posts	post	NNS
cord-345879-nbfg47x5	157	1	Angiotensin	angiotensin	NN
cord-345879-nbfg47x5	157	2	-	-	HYPH
cord-345879-nbfg47x5	157	3	converting	convert	VBG
cord-345879-nbfg47x5	157	4	enzyme	enzyme	NN
cord-345879-nbfg47x5	157	5	2	2	CD
cord-345879-nbfg47x5	157	6	protects	protect	VBZ
cord-345879-nbfg47x5	157	7	from	from	IN
cord-345879-nbfg47x5	157	8	severe	severe	JJ
cord-345879-nbfg47x5	157	9	acute	acute	JJ
cord-345879-nbfg47x5	157	10	lung	lung	NN
cord-345879-nbfg47x5	157	11	failure	failure	NN
cord-345879-nbfg47x5	157	12	Expression	expression	NN
cord-345879-nbfg47x5	157	13	and	and	CC
cord-345879-nbfg47x5	157	14	function	function	NN
cord-345879-nbfg47x5	157	15	of	of	IN
cord-345879-nbfg47x5	157	16	genes	gene	NNS
cord-345879-nbfg47x5	157	17	encoding	encode	VBG
cord-345879-nbfg47x5	157	18	cholinergic	cholinergic	JJ
cord-345879-nbfg47x5	157	19	components	component	NNS
cord-345879-nbfg47x5	157	20	in	in	IN
cord-345879-nbfg47x5	157	21	murine	murine	JJ
cord-345879-nbfg47x5	157	22	immune	immune	JJ
cord-345879-nbfg47x5	157	23	cells	cell	NNS
cord-345879-nbfg47x5	157	24	Vagus	vagus	NN
cord-345879-nbfg47x5	157	25	nerve	nerve	JJ
cord-345879-nbfg47x5	157	26	stimulation	stimulation	NN
cord-345879-nbfg47x5	157	27	inhibits	inhibit	VBZ
cord-345879-nbfg47x5	157	28	cytokine	cytokine	JJ
cord-345879-nbfg47x5	157	29	production	production	NN
cord-345879-nbfg47x5	157	30	and	and	CC
cord-345879-nbfg47x5	157	31	attenuates	attenuate	VBZ
cord-345879-nbfg47x5	157	32	disease	disease	NN
cord-345879-nbfg47x5	157	33	severity	severity	NN
cord-345879-nbfg47x5	157	34	in	in	IN
cord-345879-nbfg47x5	157	35	rheumatoid	rheumatoid	NN
cord-345879-nbfg47x5	157	36	arthritis	arthritis	NN
cord-345879-nbfg47x5	158	1	Autonomic	autonomic	JJ
cord-345879-nbfg47x5	158	2	dysfunction	dysfunction	NN
cord-345879-nbfg47x5	158	3	precedes	precede	VBZ
cord-345879-nbfg47x5	158	4	development	development	NN
cord-345879-nbfg47x5	158	5	of	of	IN
cord-345879-nbfg47x5	158	6	rheumatoid	rheumatoid	NNP
cord-345879-nbfg47x5	158	7	arthritis	arthritis	NN
cord-345879-nbfg47x5	158	8	:	:	:
cord-345879-nbfg47x5	158	9	a	a	DT
cord-345879-nbfg47x5	158	10	prospective	prospective	JJ
cord-345879-nbfg47x5	158	11	cohort	cohort	NN
cord-345879-nbfg47x5	158	12	study	study	NN
cord-345879-nbfg47x5	158	13	ACE-2	ACE-2	NNP
cord-345879-nbfg47x5	158	14	expression	expression	NN
cord-345879-nbfg47x5	158	15	in	in	IN
cord-345879-nbfg47x5	158	16	the	the	DT
cord-345879-nbfg47x5	158	17	small	small	JJ
cord-345879-nbfg47x5	158	18	airway	airway	NN
cord-345879-nbfg47x5	158	19	epithelia	epithelium	NNS
cord-345879-nbfg47x5	158	20	of	of	IN
cord-345879-nbfg47x5	158	21	smokers	smoker	NNS
cord-345879-nbfg47x5	158	22	and	and	CC
cord-345879-nbfg47x5	158	23	COPD	COPD	NNP
cord-345879-nbfg47x5	158	24	patients	patient	NNS
cord-345879-nbfg47x5	158	25	:	:	:
cord-345879-nbfg47x5	158	26	implications	implication	NNS
cord-345879-nbfg47x5	158	27	for	for	IN
cord-345879-nbfg47x5	158	28	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	158	29	The	the	DT
cord-345879-nbfg47x5	158	30	neuroinvasive	neuroinvasive	JJ
cord-345879-nbfg47x5	158	31	potential	potential	NN
cord-345879-nbfg47x5	158	32	of	of	IN
cord-345879-nbfg47x5	158	33	SARS	SARS	NNP
cord-345879-nbfg47x5	158	34	-	-	HYPH
cord-345879-nbfg47x5	158	35	CoV2	CoV2	NNP
cord-345879-nbfg47x5	158	36	may	may	MD
cord-345879-nbfg47x5	158	37	play	play	VB
cord-345879-nbfg47x5	158	38	a	a	DT
cord-345879-nbfg47x5	158	39	role	role	NN
cord-345879-nbfg47x5	158	40	in	in	IN
cord-345879-nbfg47x5	158	41	the	the	DT
cord-345879-nbfg47x5	158	42	respiratory	respiratory	JJ
cord-345879-nbfg47x5	158	43	failure	failure	NN
cord-345879-nbfg47x5	158	44	of	of	IN
cord-345879-nbfg47x5	158	45	COVID-19	covid-19	JJ
cord-345879-nbfg47x5	158	46	patients	patient	NNS
cord-345879-nbfg47x5	158	47	Regulating	regulate	VBG
cord-345879-nbfg47x5	158	48	autonomic	autonomic	JJ
cord-345879-nbfg47x5	158	49	nervous	nervous	JJ
cord-345879-nbfg47x5	158	50	system	system	NN
cord-345879-nbfg47x5	158	51	homeostasis	homeostasis	NN
cord-345879-nbfg47x5	158	52	improves	improve	VBZ
cord-345879-nbfg47x5	158	53	pulmonary	pulmonary	JJ
cord-345879-nbfg47x5	158	54	function	function	NN
cord-345879-nbfg47x5	158	55	in	in	IN
cord-345879-nbfg47x5	158	56	rabbits	rabbit	NNS
cord-345879-nbfg47x5	158	57	with	with	IN
cord-345879-nbfg47x5	158	58	acute	acute	JJ
cord-345879-nbfg47x5	158	59	lung	lung	NN
cord-345879-nbfg47x5	158	60	injury	injury	NN
cord-345879-nbfg47x5	158	61	Neurologic	neurologic	JJ
cord-345879-nbfg47x5	158	62	manifestations	manifestation	NNS
cord-345879-nbfg47x5	158	63	of	of	IN
cord-345879-nbfg47x5	158	64	hospitalized	hospitalize	VBN
cord-345879-nbfg47x5	158	65	patients	patient	NNS
cord-345879-nbfg47x5	158	66	with	with	IN
cord-345879-nbfg47x5	158	67	coronavirus	coronavirus	NN
cord-345879-nbfg47x5	158	68	disease	disease	NN
cord-345879-nbfg47x5	158	69	2019	2019	CD
cord-345879-nbfg47x5	158	70	in	in	IN
cord-345879-nbfg47x5	158	71	Wuhan	Wuhan	NNP
cord-345879-nbfg47x5	158	72	,	,	,
cord-345879-nbfg47x5	158	73	China	China	NNP
cord-345879-nbfg47x5	158	74	Minireview	Minireview	NNP
cord-345879-nbfg47x5	158	75	:	:	:
cord-345879-nbfg47x5	158	76	divergent	divergent	JJ
cord-345879-nbfg47x5	158	77	roles	role	NNS
cord-345879-nbfg47x5	158	78	of	of	IN
cord-345879-nbfg47x5	158	79	alpha7	alpha7	NN
cord-345879-nbfg47x5	158	80	nicotinic	nicotinic	JJ
cord-345879-nbfg47x5	158	81	acetylcholine	acetylcholine	NN
cord-345879-nbfg47x5	158	82	receptors	receptor	NNS
cord-345879-nbfg47x5	158	83	expressed	express	VBD
cord-345879-nbfg47x5	158	84	on	on	IN
cord-345879-nbfg47x5	158	85	antigen	antigen	NN
cord-345879-nbfg47x5	158	86	-	-	HYPH
cord-345879-nbfg47x5	158	87	presenting	present	VBG
cord-345879-nbfg47x5	158	88	cells	cell	NNS
cord-345879-nbfg47x5	158	89	and	and	CC
cord-345879-nbfg47x5	158	90	CD4(+	cd4(+	JJ
cord-345879-nbfg47x5	158	91	)	)	-RRB-
cord-345879-nbfg47x5	158	92	T	t	NN
cord-345879-nbfg47x5	158	93	cells	cell	NNS
cord-345879-nbfg47x5	158	94	in	in	IN
cord-345879-nbfg47x5	158	95	the	the	DT
cord-345879-nbfg47x5	158	96	regulation	regulation	NN
cord-345879-nbfg47x5	158	97	of	of	IN
cord-345879-nbfg47x5	159	1	T	T	NNP
cord-345879-nbfg47x5	159	2	cell	cell	NN
cord-345879-nbfg47x5	159	3	differentiation	differentiation	NN
cord-345879-nbfg47x5	159	4	A	a	DT
cord-345879-nbfg47x5	159	5	distinct	distinct	JJ
cord-345879-nbfg47x5	159	6	vagal	vagal	JJ
cord-345879-nbfg47x5	159	7	anti	anti	JJ
cord-345879-nbfg47x5	159	8	-	-	JJ
cord-345879-nbfg47x5	159	9	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	159	10	pathway	pathway	NN
cord-345879-nbfg47x5	159	11	modulates	modulate	VBZ
cord-345879-nbfg47x5	159	12	intestinal	intestinal	JJ
cord-345879-nbfg47x5	159	13	muscularis	muscularis	NNP
cord-345879-nbfg47x5	159	14	resident	resident	NN
cord-345879-nbfg47x5	159	15	macrophages	macrophage	NNS
cord-345879-nbfg47x5	159	16	independent	independent	JJ
cord-345879-nbfg47x5	159	17	of	of	IN
cord-345879-nbfg47x5	159	18	the	the	DT
cord-345879-nbfg47x5	159	19	spleen	spleen	NN
cord-345879-nbfg47x5	159	20	Electric	electric	JJ
cord-345879-nbfg47x5	159	21	stimulation	stimulation	NN
cord-345879-nbfg47x5	159	22	of	of	IN
cord-345879-nbfg47x5	159	23	the	the	DT
cord-345879-nbfg47x5	159	24	vagus	vagus	NN
cord-345879-nbfg47x5	159	25	nerve	nerve	NN
cord-345879-nbfg47x5	159	26	reduced	reduce	VBN
cord-345879-nbfg47x5	159	27	mouse	mouse	NN
cord-345879-nbfg47x5	159	28	neuroinflammation	neuroinflammation	NN
cord-345879-nbfg47x5	159	29	induced	induce	VBN
cord-345879-nbfg47x5	159	30	by	by	IN
cord-345879-nbfg47x5	159	31	lipopolysaccharide	lipopolysaccharide	NN
cord-345879-nbfg47x5	159	32	Low	low	JJ
cord-345879-nbfg47x5	159	33	incidence	incidence	NN
cord-345879-nbfg47x5	159	34	of	of	IN
cord-345879-nbfg47x5	159	35	daily	daily	JJ
cord-345879-nbfg47x5	159	36	active	active	JJ
cord-345879-nbfg47x5	159	37	tobacco	tobacco	NN
cord-345879-nbfg47x5	159	38	smoking	smoking	NN
cord-345879-nbfg47x5	159	39	in	in	IN
cord-345879-nbfg47x5	159	40	patients	patient	NNS
cord-345879-nbfg47x5	159	41	with	with	IN
cord-345879-nbfg47x5	159	42	symptomatic	symptomatic	JJ
cord-345879-nbfg47x5	159	43	COVID-19	covid-19	NN
cord-345879-nbfg47x5	159	44	.	.	.
cord-345879-nbfg47x5	160	1	Qeios	Qeios	NNP
cord-345879-nbfg47x5	160	2	Olfactory	olfactory	JJ
cord-345879-nbfg47x5	160	3	transmission	transmission	NN
cord-345879-nbfg47x5	160	4	of	of	IN
cord-345879-nbfg47x5	160	5	neurotropic	neurotropic	NNP
cord-345879-nbfg47x5	160	6	viruses	virus	NNS
cord-345879-nbfg47x5	160	7	Clinical	clinical	JJ
cord-345879-nbfg47x5	160	8	characteristics	characteristic	NNS
cord-345879-nbfg47x5	160	9	of	of	IN
cord-345879-nbfg47x5	160	10	COVID-19	covid-19	JJ
cord-345879-nbfg47x5	160	11	patients	patient	NNS
cord-345879-nbfg47x5	160	12	with	with	IN
cord-345879-nbfg47x5	160	13	digestive	digestive	JJ
cord-345879-nbfg47x5	160	14	symptoms	symptom	NNS
cord-345879-nbfg47x5	160	15	in	in	IN
cord-345879-nbfg47x5	160	16	Hubei	Hubei	NNP
cord-345879-nbfg47x5	160	17	,	,	,
cord-345879-nbfg47x5	160	18	China	China	NNP
cord-345879-nbfg47x5	160	19	:	:	:
cord-345879-nbfg47x5	160	20	a	a	DT
cord-345879-nbfg47x5	160	21	descriptive	descriptive	JJ
cord-345879-nbfg47x5	160	22	,	,	,
cord-345879-nbfg47x5	160	23	cross	cross	JJ
cord-345879-nbfg47x5	160	24	-	-	JJ
cord-345879-nbfg47x5	160	25	sectional	sectional	JJ
cord-345879-nbfg47x5	160	26	,	,	,
cord-345879-nbfg47x5	160	27	Multicenter	Multicenter	NNP
cord-345879-nbfg47x5	160	28	Study	Study	NNP
cord-345879-nbfg47x5	160	29	Relationship	Relationship	NNP
cord-345879-nbfg47x5	160	30	between	between	IN
cord-345879-nbfg47x5	160	31	vagal	vagal	JJ
cord-345879-nbfg47x5	160	32	tone	tone	NN
cord-345879-nbfg47x5	160	33	,	,	,
cord-345879-nbfg47x5	160	34	cortisol	cortisol	NN
cord-345879-nbfg47x5	160	35	,	,	,
cord-345879-nbfg47x5	160	36	TNF	TNF	NNP
cord-345879-nbfg47x5	160	37	-	-	HYPH
cord-345879-nbfg47x5	160	38	alpha	alpha	NN
cord-345879-nbfg47x5	160	39	,	,	,
cord-345879-nbfg47x5	160	40	epinephrine	epinephrine	NN
cord-345879-nbfg47x5	160	41	and	and	CC
cord-345879-nbfg47x5	160	42	negative	negative	JJ
cord-345879-nbfg47x5	160	43	affects	affect	NNS
cord-345879-nbfg47x5	160	44	in	in	IN
cord-345879-nbfg47x5	160	45	Crohn	Crohn	NNP
cord-345879-nbfg47x5	160	46	's	's	POS
cord-345879-nbfg47x5	160	47	disease	disease	NN
cord-345879-nbfg47x5	160	48	and	and	CC
cord-345879-nbfg47x5	160	49	irritable	irritable	JJ
cord-345879-nbfg47x5	160	50	bowel	bowel	NN
cord-345879-nbfg47x5	160	51	syndrome	syndrome	NN
cord-345879-nbfg47x5	160	52	Th17	Th17	NNP
cord-345879-nbfg47x5	161	1	lymphocytes	lymphocyte	NNS
cord-345879-nbfg47x5	161	2	drive	drive	VBP
cord-345879-nbfg47x5	161	3	vascular	vascular	JJ
cord-345879-nbfg47x5	161	4	and	and	CC
cord-345879-nbfg47x5	161	5	neuronal	neuronal	JJ
cord-345879-nbfg47x5	161	6	deficits	deficit	NNS
cord-345879-nbfg47x5	161	7	in	in	IN
cord-345879-nbfg47x5	161	8	a	a	DT
cord-345879-nbfg47x5	161	9	mouse	mouse	NN
cord-345879-nbfg47x5	161	10	model	model	NN
cord-345879-nbfg47x5	161	11	of	of	IN
cord-345879-nbfg47x5	161	12	postinfectious	postinfectious	NNP
cord-345879-nbfg47x5	161	13	autoimmune	autoimmune	NNP
cord-345879-nbfg47x5	161	14	encephalitis	encephalitis	RB
cord-345879-nbfg47x5	162	1	The	the	DT
cord-345879-nbfg47x5	162	2	fiber	fiber	NN
cord-345879-nbfg47x5	162	3	composition	composition	NN
cord-345879-nbfg47x5	162	4	of	of	IN
cord-345879-nbfg47x5	162	5	the	the	DT
cord-345879-nbfg47x5	162	6	abdominal	abdominal	JJ
cord-345879-nbfg47x5	162	7	vagus	vagus	NN
cord-345879-nbfg47x5	162	8	of	of	IN
cord-345879-nbfg47x5	162	9	the	the	DT
cord-345879-nbfg47x5	162	10	rat	rat	NN
cord-345879-nbfg47x5	162	11	Dynamic	dynamic	JJ
cord-345879-nbfg47x5	162	12	causal	causal	NN
cord-345879-nbfg47x5	162	13	modelling	modelling	NN
cord-345879-nbfg47x5	162	14	and	and	CC
cord-345879-nbfg47x5	162	15	physiological	physiological	JJ
cord-345879-nbfg47x5	162	16	confounds	confound	NNS
cord-345879-nbfg47x5	162	17	:	:	:
cord-345879-nbfg47x5	163	1	a	a	DT
cord-345879-nbfg47x5	163	2	functional	functional	JJ
cord-345879-nbfg47x5	163	3	MRI	MRI	NNP
cord-345879-nbfg47x5	163	4	study	study	NN
cord-345879-nbfg47x5	163	5	of	of	IN
cord-345879-nbfg47x5	163	6	vagus	vagus	JJ
cord-345879-nbfg47x5	163	7	nerve	nerve	NN
cord-345879-nbfg47x5	163	8	stimulation	stimulation	NN
cord-345879-nbfg47x5	163	9	Splenic	Splenic	NNP
cord-345879-nbfg47x5	163	10	nerve	nerve	NN
cord-345879-nbfg47x5	163	11	is	be	VBZ
cord-345879-nbfg47x5	163	12	required	require	VBN
cord-345879-nbfg47x5	163	13	for	for	IN
cord-345879-nbfg47x5	163	14	cholinergic	cholinergic	JJ
cord-345879-nbfg47x5	163	15	antiinflammatory	antiinflammatory	JJ
cord-345879-nbfg47x5	163	16	pathway	pathway	NN
cord-345879-nbfg47x5	163	17	control	control	NN
cord-345879-nbfg47x5	163	18	of	of	IN
cord-345879-nbfg47x5	163	19	TNF	TNF	NNP
cord-345879-nbfg47x5	163	20	in	in	IN
cord-345879-nbfg47x5	163	21	endotoxemia	endotoxemia	NN
cord-345879-nbfg47x5	163	22	Vagus	Vagus	NNP
cord-345879-nbfg47x5	163	23	nerve	nerve	NN
cord-345879-nbfg47x5	163	24	stimulation	stimulation	NN
cord-345879-nbfg47x5	163	25	and	and	CC
cord-345879-nbfg47x5	163	26	Neurotrophins	Neurotrophins	NNP
cord-345879-nbfg47x5	163	27	:	:	:
cord-345879-nbfg47x5	163	28	a	a	DT
cord-345879-nbfg47x5	163	29	biological	biological	JJ
cord-345879-nbfg47x5	163	30	psychiatric	psychiatric	JJ
cord-345879-nbfg47x5	163	31	perspective	perspective	NN
cord-345879-nbfg47x5	164	1	COVID-19	covid-19	VB
cord-345879-nbfg47x5	164	2	and	and	CC
cord-345879-nbfg47x5	164	3	smoking	smoking	NN
cord-345879-nbfg47x5	164	4	:	:	:
cord-345879-nbfg47x5	164	5	is	be	VBZ
cord-345879-nbfg47x5	164	6	nicotine	nicotine	NN
cord-345879-nbfg47x5	164	7	the	the	DT
cord-345879-nbfg47x5	164	8	hidden	hide	VBN
cord-345879-nbfg47x5	164	9	link	link	NN
cord-345879-nbfg47x5	164	10	?	?	.
cord-345879-nbfg47x5	165	1	A	a	DT
cord-345879-nbfg47x5	165	2	12-month	12-month	JJ
cord-345879-nbfg47x5	165	3	pilot	pilot	NN
cord-345879-nbfg47x5	165	4	study	study	NN
cord-345879-nbfg47x5	165	5	outcomes	outcome	NNS
cord-345879-nbfg47x5	165	6	of	of	IN
cord-345879-nbfg47x5	165	7	vagus	vagus	JJ
cord-345879-nbfg47x5	165	8	nerve	nerve	NN
cord-345879-nbfg47x5	165	9	stimulation	stimulation	NN
cord-345879-nbfg47x5	165	10	in	in	IN
cord-345879-nbfg47x5	165	11	Crohn	Crohn	NNP
cord-345879-nbfg47x5	165	12	's	's	POS
cord-345879-nbfg47x5	165	13	disease	disease	NN
cord-345879-nbfg47x5	166	1	The	the	DT
cord-345879-nbfg47x5	166	2	use	use	NN
cord-345879-nbfg47x5	166	3	of	of	IN
cord-345879-nbfg47x5	166	4	non	non	JJ
cord-345879-nbfg47x5	166	5	-	-	JJ
cord-345879-nbfg47x5	166	6	invasive	invasive	JJ
cord-345879-nbfg47x5	166	7	Vagus	vagus	NN
cord-345879-nbfg47x5	166	8	nerve	nerve	NN
cord-345879-nbfg47x5	166	9	stimulation	stimulation	NN
cord-345879-nbfg47x5	166	10	to	to	TO
cord-345879-nbfg47x5	166	11	treat	treat	VB
cord-345879-nbfg47x5	166	12	respiratory	respiratory	JJ
cord-345879-nbfg47x5	166	13	symptoms	symptom	NNS
cord-345879-nbfg47x5	166	14	associated	associate	VBN
cord-345879-nbfg47x5	166	15	with	with	IN
cord-345879-nbfg47x5	166	16	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	166	17	:	:	:
cord-345879-nbfg47x5	166	18	a	a	DT
cord-345879-nbfg47x5	166	19	theoretical	theoretical	JJ
cord-345879-nbfg47x5	166	20	hypothesis	hypothesis	NN
cord-345879-nbfg47x5	166	21	and	and	CC
cord-345879-nbfg47x5	166	22	early	early	JJ
cord-345879-nbfg47x5	166	23	clinical	clinical	JJ
cord-345879-nbfg47x5	166	24	experience	experience	NN
cord-345879-nbfg47x5	166	25	Abdominal	abdominal	JJ
cord-345879-nbfg47x5	166	26	vagus	vagus	NN
cord-345879-nbfg47x5	166	27	nerve	nerve	NN
cord-345879-nbfg47x5	166	28	stimulation	stimulation	NN
cord-345879-nbfg47x5	166	29	as	as	IN
cord-345879-nbfg47x5	166	30	a	a	DT
cord-345879-nbfg47x5	166	31	new	new	JJ
cord-345879-nbfg47x5	166	32	therapeutic	therapeutic	JJ
cord-345879-nbfg47x5	166	33	approach	approach	NN
cord-345879-nbfg47x5	166	34	to	to	TO
cord-345879-nbfg47x5	166	35	prevent	prevent	VB
cord-345879-nbfg47x5	166	36	postoperative	postoperative	JJ
cord-345879-nbfg47x5	166	37	ileus	ileus	NN
cord-345879-nbfg47x5	166	38	Requisite	requisite	JJ
cord-345879-nbfg47x5	166	39	role	role	NN
cord-345879-nbfg47x5	166	40	of	of	IN
cord-345879-nbfg47x5	166	41	the	the	DT
cord-345879-nbfg47x5	166	42	cholinergic	cholinergic	JJ
cord-345879-nbfg47x5	166	43	alpha7	alpha7	NN
cord-345879-nbfg47x5	166	44	nicotinic	nicotinic	JJ
cord-345879-nbfg47x5	166	45	acetylcholine	acetylcholine	NN
cord-345879-nbfg47x5	166	46	receptor	receptor	NN
cord-345879-nbfg47x5	166	47	pathway	pathway	NN
cord-345879-nbfg47x5	166	48	in	in	IN
cord-345879-nbfg47x5	166	49	suppressing	suppress	VBG
cord-345879-nbfg47x5	166	50	gram	gram	JJ
cord-345879-nbfg47x5	166	51	-	-	HYPH
cord-345879-nbfg47x5	166	52	negative	negative	JJ
cord-345879-nbfg47x5	166	53	sepsis	sepsis	NN
cord-345879-nbfg47x5	166	54	-	-	HYPH
cord-345879-nbfg47x5	166	55	induced	induce	VBN
cord-345879-nbfg47x5	166	56	acute	acute	JJ
cord-345879-nbfg47x5	166	57	lung	lung	NN
cord-345879-nbfg47x5	166	58	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	166	59	injury	injury	NN
cord-345879-nbfg47x5	166	60	Pharmacologic	Pharmacologic	NNP
cord-345879-nbfg47x5	166	61	stimulation	stimulation	NN
cord-345879-nbfg47x5	166	62	of	of	IN
cord-345879-nbfg47x5	166	63	the	the	DT
cord-345879-nbfg47x5	166	64	nicotinic	nicotinic	JJ
cord-345879-nbfg47x5	166	65	anti	anti	JJ
cord-345879-nbfg47x5	166	66	-	-	JJ
cord-345879-nbfg47x5	166	67	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	166	68	pathway	pathway	NN
cord-345879-nbfg47x5	166	69	modulates	modulate	VBZ
cord-345879-nbfg47x5	166	70	gut	gut	NN
cord-345879-nbfg47x5	166	71	and	and	CC
cord-345879-nbfg47x5	166	72	lung	lung	NN
cord-345879-nbfg47x5	166	73	injury	injury	NN
cord-345879-nbfg47x5	166	74	after	after	IN
cord-345879-nbfg47x5	166	75	hypoxia	hypoxia	NN
cord-345879-nbfg47x5	166	76	-	-	HYPH
cord-345879-nbfg47x5	166	77	reoxygenation	reoxygenation	NN
cord-345879-nbfg47x5	166	78	injury	injury	NN
cord-345879-nbfg47x5	167	1	The	the	DT
cord-345879-nbfg47x5	167	2	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	167	3	reflex	reflex	NN
cord-345879-nbfg47x5	167	4	Specific	specific	JJ
cord-345879-nbfg47x5	167	5	vagus	vagus	NN
cord-345879-nbfg47x5	167	6	nerve	nerve	NN
cord-345879-nbfg47x5	167	7	stimulation	stimulation	NN
cord-345879-nbfg47x5	167	8	parameters	parameter	NNS
cord-345879-nbfg47x5	167	9	alter	alter	VBP
cord-345879-nbfg47x5	167	10	serum	serum	NN
cord-345879-nbfg47x5	167	11	cytokine	cytokine	NN
cord-345879-nbfg47x5	167	12	levels	level	NNS
cord-345879-nbfg47x5	167	13	in	in	IN
cord-345879-nbfg47x5	167	14	the	the	DT
cord-345879-nbfg47x5	167	15	absence	absence	NN
cord-345879-nbfg47x5	167	16	of	of	IN
cord-345879-nbfg47x5	167	17	inflammation	inflammation	NN
cord-345879-nbfg47x5	167	18	Renin	renin	NN
cord-345879-nbfg47x5	167	19	-	-	HYPH
cord-345879-nbfg47x5	167	20	angiotensin	angiotensin	NN
cord-345879-nbfg47x5	167	21	-	-	HYPH
cord-345879-nbfg47x5	167	22	aldosterone	aldosterone	NN
cord-345879-nbfg47x5	167	23	system	system	NN
cord-345879-nbfg47x5	167	24	inhibitors	inhibitor	NNS
cord-345879-nbfg47x5	167	25	in	in	IN
cord-345879-nbfg47x5	167	26	patients	patient	NNS
cord-345879-nbfg47x5	167	27	with	with	IN
cord-345879-nbfg47x5	167	28	Covid-19	Covid-19	NNP
cord-345879-nbfg47x5	167	29	Cholinergic	cholinergic	JJ
cord-345879-nbfg47x5	167	30	agonists	agonist	NNS
cord-345879-nbfg47x5	168	1	inhibit	inhibit	VB
cord-345879-nbfg47x5	168	2	HMGB1	HMGB1	NNP
cord-345879-nbfg47x5	168	3	release	release	NN
cord-345879-nbfg47x5	168	4	and	and	CC
cord-345879-nbfg47x5	168	5	improve	improve	VB
cord-345879-nbfg47x5	168	6	survival	survival	NN
cord-345879-nbfg47x5	168	7	in	in	IN
cord-345879-nbfg47x5	169	1	experimental	experimental	JJ
cord-345879-nbfg47x5	169	2	sepsis	sepsis	NN
cord-345879-nbfg47x5	169	3	Nicotinic	Nicotinic	NNP
cord-345879-nbfg47x5	169	4	acetylcholine	acetylcholine	NN
cord-345879-nbfg47x5	169	5	receptor	receptor	NN
cord-345879-nbfg47x5	169	6	alpha7	alpha7	NN
cord-345879-nbfg47x5	169	7	subunit	subunit	NN
cord-345879-nbfg47x5	169	8	is	be	VBZ
cord-345879-nbfg47x5	169	9	an	an	DT
cord-345879-nbfg47x5	169	10	essential	essential	JJ
cord-345879-nbfg47x5	169	11	regulator	regulator	NN
cord-345879-nbfg47x5	169	12	of	of	IN
cord-345879-nbfg47x5	169	13	inflammation	inflammation	NN
cord-345879-nbfg47x5	169	14	Detection	detection	NN
cord-345879-nbfg47x5	169	15	of	of	IN
cord-345879-nbfg47x5	169	16	SARS	SARS	NNP
cord-345879-nbfg47x5	169	17	-	-	HYPH
cord-345879-nbfg47x5	169	18	CoV-2	CoV-2	NNP
cord-345879-nbfg47x5	169	19	in	in	IN
cord-345879-nbfg47x5	169	20	different	different	JJ
cord-345879-nbfg47x5	169	21	types	type	NNS
cord-345879-nbfg47x5	169	22	of	of	IN
cord-345879-nbfg47x5	169	23	clinical	clinical	JJ
cord-345879-nbfg47x5	169	24	specimens	specimen	NNS
cord-345879-nbfg47x5	169	25	Nervous	nervous	JJ
cord-345879-nbfg47x5	169	26	system	system	NN
cord-345879-nbfg47x5	169	27	involvement	involvement	NN
cord-345879-nbfg47x5	169	28	after	after	IN
cord-345879-nbfg47x5	169	29	infection	infection	NN
cord-345879-nbfg47x5	169	30	with	with	IN
cord-345879-nbfg47x5	169	31	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	169	32	and	and	CC
cord-345879-nbfg47x5	169	33	other	other	JJ
cord-345879-nbfg47x5	169	34	coronaviruses	coronaviruse	NNS
cord-345879-nbfg47x5	170	1	Survivors	survivor	NNS
cord-345879-nbfg47x5	170	2	of	of	IN
cord-345879-nbfg47x5	170	3	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	170	4	are	be	VBP
cord-345879-nbfg47x5	170	5	at	at	IN
cord-345879-nbfg47x5	170	6	high	high	JJ
cord-345879-nbfg47x5	170	7	risk	risk	NN
cord-345879-nbfg47x5	170	8	of	of	IN
cord-345879-nbfg47x5	170	9	posttraumatic	posttraumatic	JJ
cord-345879-nbfg47x5	170	10	stress	stress	NN
cord-345879-nbfg47x5	170	11	disorder	disorder	NN
cord-345879-nbfg47x5	170	12	.	.	.
cord-345879-nbfg47x5	171	1	Global	global	JJ
cord-345879-nbfg47x5	171	2	health	health	NN
cord-345879-nbfg47x5	171	3	research	research	NN
cord-345879-nbfg47x5	171	4	and	and	CC
cord-345879-nbfg47x5	171	5	policy	policy	NN
cord-345879-nbfg47x5	171	6	A	a	DT
cord-345879-nbfg47x5	171	7	novel	novel	JJ
cord-345879-nbfg47x5	171	8	regulator	regulator	NN
cord-345879-nbfg47x5	171	9	of	of	IN
cord-345879-nbfg47x5	171	10	lung	lung	NN
cord-345879-nbfg47x5	171	11	inflammation	inflammation	NN
cord-345879-nbfg47x5	171	12	and	and	CC
cord-345879-nbfg47x5	171	13	immunity	immunity	NN
cord-345879-nbfg47x5	171	14	:	:	:
cord-345879-nbfg47x5	171	15	pulmonary	pulmonary	JJ
cord-345879-nbfg47x5	171	16	parasympathetic	parasympathetic	JJ
cord-345879-nbfg47x5	171	17	inflammatory	inflammatory	JJ
cord-345879-nbfg47x5	171	18	reflex	reflex	NN
cord-345879-nbfg47x5	172	1	The	the	DT
cord-345879-nbfg47x5	172	2	pathogenesis	pathogenesis	NN
cord-345879-nbfg47x5	172	3	and	and	CC
cord-345879-nbfg47x5	172	4	treatment	treatment	NN
cord-345879-nbfg47x5	172	5	of	of	IN
cord-345879-nbfg47x5	172	6	the	the	DT
cord-345879-nbfg47x5	172	7	'	'	``
cord-345879-nbfg47x5	172	8	cytokine	cytokine	NN
cord-345879-nbfg47x5	172	9	Storm	storm	NN
cord-345879-nbfg47x5	172	10	'	'	''
cord-345879-nbfg47x5	172	11	in	in	IN
cord-345879-nbfg47x5	172	12	COVID-19	COVID-19	NNP
cord-345879-nbfg47x5	172	13	Autonomic	Autonomic	NNP
cord-345879-nbfg47x5	172	14	dysfunction	dysfunction	NN
cord-345879-nbfg47x5	172	15	and	and	CC
cord-345879-nbfg47x5	172	16	chronic	chronic	JJ
cord-345879-nbfg47x5	172	17	disease	disease	NN
cord-345879-nbfg47x5	172	18	Specific	specific	JJ
cord-345879-nbfg47x5	172	19	ACE2	ACE2	NNP
cord-345879-nbfg47x5	172	20	expression	expression	NN
cord-345879-nbfg47x5	172	21	in	in	IN
cord-345879-nbfg47x5	172	22	small	small	JJ
cord-345879-nbfg47x5	172	23	intestinal	intestinal	JJ
cord-345879-nbfg47x5	172	24	enterocytes	enterocyte	NNS
cord-345879-nbfg47x5	172	25	may	may	MD
cord-345879-nbfg47x5	172	26	cause	cause	VB
cord-345879-nbfg47x5	172	27	gastrointestinal	gastrointestinal	JJ
cord-345879-nbfg47x5	172	28	symptoms	symptom	NNS
cord-345879-nbfg47x5	172	29	and	and	CC
cord-345879-nbfg47x5	172	30	injury	injury	NN
cord-345879-nbfg47x5	172	31	after	after	IN
cord-345879-nbfg47x5	172	32	2019-nCoV	2019-ncov	CD
cord-345879-nbfg47x5	172	33	infection	infection	NN
cord-345879-nbfg47x5	172	34	Publisher	publisher	NN
cord-345879-nbfg47x5	172	35	's	's	POS
cord-345879-nbfg47x5	172	36	Note	Note	NNP
cord-345879-nbfg47x5	172	37	Springer	Springer	NNP
cord-345879-nbfg47x5	172	38	Nature	Nature	NNP
cord-345879-nbfg47x5	172	39	remains	remain	VBZ
cord-345879-nbfg47x5	172	40	neutral	neutral	JJ
cord-345879-nbfg47x5	172	41	with	with	IN
cord-345879-nbfg47x5	172	42	regard	regard	NN
cord-345879-nbfg47x5	172	43	to	to	IN
cord-345879-nbfg47x5	172	44	jurisdictional	jurisdictional	JJ
cord-345879-nbfg47x5	172	45	claims	claim	NNS
cord-345879-nbfg47x5	172	46	in	in	IN
cord-345879-nbfg47x5	172	47	published	publish	VBN
cord-345879-nbfg47x5	172	48	maps	map	NNS
cord-345879-nbfg47x5	172	49	and	and	CC
cord-345879-nbfg47x5	172	50	institutional	institutional	JJ
cord-345879-nbfg47x5	172	51	affiliations	affiliation	NNS
cord-345879-nbfg47x5	172	52	Authors	author	NNS
cord-345879-nbfg47x5	172	53	'	'	POS
cord-345879-nbfg47x5	172	54	contributions	contribution	NNS
cord-345879-nbfg47x5	172	55	BB	BB	NNP
cord-345879-nbfg47x5	172	56	has	have	VBZ
cord-345879-nbfg47x5	172	57	written	write	VBN
cord-345879-nbfg47x5	172	58	the	the	DT
cord-345879-nbfg47x5	172	59	manuscript	manuscript	NN
cord-345879-nbfg47x5	172	60	;	;	:
cord-345879-nbfg47x5	172	61	VS	VS	NNP
cord-345879-nbfg47x5	172	62	and	and	CC
cord-345879-nbfg47x5	172	63	SP	SP	NNP
cord-345879-nbfg47x5	172	64	have	have	VBP
cord-345879-nbfg47x5	172	65	revised	revise	VBN
cord-345879-nbfg47x5	172	66	the	the	DT
cord-345879-nbfg47x5	172	67	manuscript	manuscript	NN
cord-345879-nbfg47x5	172	68	.	.	.
cord-345879-nbfg47x5	173	1	The	the	DT
cord-345879-nbfg47x5	173	2	author(s	author(s	NNP
cord-345879-nbfg47x5	173	3	)	)	-RRB-
cord-345879-nbfg47x5	173	4	read	read	VBD
cord-345879-nbfg47x5	173	5	and	and	CC
cord-345879-nbfg47x5	173	6	approved	approve	VBD
cord-345879-nbfg47x5	173	7	the	the	DT
cord-345879-nbfg47x5	173	8	final	final	JJ
cord-345879-nbfg47x5	173	9	manuscript	manuscript	NN
cord-345879-nbfg47x5	173	10	.	.	.
cord-345879-nbfg47x5	174	1	The	the	DT
cord-345879-nbfg47x5	174	2	authors	author	NNS
cord-345879-nbfg47x5	174	3	thank	thank	VBP
cord-345879-nbfg47x5	174	4	INSERM	INSERM	NNP
cord-345879-nbfg47x5	174	5	,	,	,
cord-345879-nbfg47x5	174	6	DGOS	DGOS	NNP
cord-345879-nbfg47x5	174	7	(	(	-LRB-
cord-345879-nbfg47x5	174	8	Appel	Appel	NNP
cord-345879-nbfg47x5	174	9	à	à	FW
cord-345879-nbfg47x5	174	10	Projet	Projet	NNP
cord-345879-nbfg47x5	174	11	Translationnel	Translationnel	NNP
cord-345879-nbfg47x5	174	12	,	,	,
cord-345879-nbfg47x5	174	13	2011	2011	CD
cord-345879-nbfg47x5	174	14	)	)	-RRB-
cord-345879-nbfg47x5	174	15	,	,	,
cord-345879-nbfg47x5	174	16	and	and	CC
cord-345879-nbfg47x5	174	17	the	the	DT
cord-345879-nbfg47x5	174	18	DRCI	DRCI	NNP
cord-345879-nbfg47x5	174	19	from	from	IN
cord-345879-nbfg47x5	174	20	the	the	DT
cord-345879-nbfg47x5	174	21	Grenoble	Grenoble	NNP
cord-345879-nbfg47x5	174	22	Hospital	Hospital	NNP
cord-345879-nbfg47x5	174	23	for	for	IN
cord-345879-nbfg47x5	174	24	their	-PRON-	PRP$
cord-345879-nbfg47x5	174	25	funding	funding	NN
cord-345879-nbfg47x5	174	26	.	.	.
cord-345879-nbfg47x5	175	1	Ethics	ethic	NNS
cord-345879-nbfg47x5	175	2	approval	approval	NN
cord-345879-nbfg47x5	175	3	and	and	CC
cord-345879-nbfg47x5	175	4	consent	consent	NN
cord-345879-nbfg47x5	175	5	to	to	TO
cord-345879-nbfg47x5	175	6	participate	participate	VB
cord-345879-nbfg47x5	175	7	not	not	RB
cord-345879-nbfg47x5	175	8	applicable	applicable	JJ
cord-345879-nbfg47x5	175	9	(	(	-LRB-
cord-345879-nbfg47x5	175	10	NA	NA	NNP
cord-345879-nbfg47x5	175	11	)	)	-RRB-
cord-345879-nbfg47x5	175	12	.	.	.