id sid tid token lemma pos cord-345304-n74m5ucs 1 1 key key NN cord-345304-n74m5ucs 1 2 : : : cord-345304-n74m5ucs 2 1 cord-345304-n74m5ucs cord-345304-n74m5ucs NNP cord-345304-n74m5ucs 3 1 authors author NNS cord-345304-n74m5ucs 3 2 : : : cord-345304-n74m5ucs 3 3 Safadi Safadi NNP cord-345304-n74m5ucs 3 4 , , , cord-345304-n74m5ucs 3 5 Marco Marco NNP cord-345304-n74m5ucs 3 6 Aurelio Aurelio NNP cord-345304-n74m5ucs 3 7 Palazzi Palazzi NNPS cord-345304-n74m5ucs 3 8 ; ; : cord-345304-n74m5ucs 3 9 da da NNP cord-345304-n74m5ucs 3 10 Silva Silva NNP cord-345304-n74m5ucs 3 11 , , , cord-345304-n74m5ucs 3 12 Clovis Clovis NNP cord-345304-n74m5ucs 3 13 Artur Artur NNP cord-345304-n74m5ucs 3 14 Almeida Almeida NNP cord-345304-n74m5ucs 3 15 title title NN cord-345304-n74m5ucs 3 16 : : : cord-345304-n74m5ucs 3 17 THE the DT cord-345304-n74m5ucs 3 18 CHALLENGING challenging JJ cord-345304-n74m5ucs 3 19 AND and CC cord-345304-n74m5ucs 3 20 UNPREDICTABLE unpredictable JJ cord-345304-n74m5ucs 3 21 SPECTRUM spectrum NN cord-345304-n74m5ucs 3 22 OF of IN cord-345304-n74m5ucs 3 23 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 3 24 IN in IN cord-345304-n74m5ucs 3 25 CHILDREN child NNS cord-345304-n74m5ucs 3 26 AND and CC cord-345304-n74m5ucs 3 27 ADOLESCENTS adolescent NNS cord-345304-n74m5ucs 3 28 date date NN cord-345304-n74m5ucs 3 29 : : : cord-345304-n74m5ucs 3 30 2020 2020 CD cord-345304-n74m5ucs 3 31 - - HYPH cord-345304-n74m5ucs 3 32 09 09 CD cord-345304-n74m5ucs 3 33 - - HYPH cord-345304-n74m5ucs 3 34 07 07 CD cord-345304-n74m5ucs 3 35 journal journal NN cord-345304-n74m5ucs 3 36 : : : cord-345304-n74m5ucs 4 1 Rev Rev NNP cord-345304-n74m5ucs 4 2 Paul Paul NNP cord-345304-n74m5ucs 4 3 Pediatr Pediatr NNP cord-345304-n74m5ucs 4 4 DOI DOI NNP cord-345304-n74m5ucs 4 5 : : : cord-345304-n74m5ucs 4 6 10.1590/1984 10.1590/1984 CD cord-345304-n74m5ucs 4 7 - - HYPH cord-345304-n74m5ucs 4 8 0462/2020/38/2020192 0462/2020/38/2020192 CD cord-345304-n74m5ucs 5 1 sha sha NNP cord-345304-n74m5ucs 5 2 : : : cord-345304-n74m5ucs 6 1 fa6efce980f5389c336d445da1cabd449b1d65b1 fa6efce980f5389c336d445da1cabd449b1d65b1 NNP cord-345304-n74m5ucs 6 2 doc_id doc_id CD cord-345304-n74m5ucs 6 3 : : : cord-345304-n74m5ucs 6 4 345304 345304 CD cord-345304-n74m5ucs 6 5 cord_uid cord_uid NNS cord-345304-n74m5ucs 6 6 : : : cord-345304-n74m5ucs 7 1 n74m5ucs n74m5ucs NNP cord-345304-n74m5ucs 8 1 nan nan NNP cord-345304-n74m5ucs 9 1 In in IN cord-345304-n74m5ucs 9 2 the the DT cord-345304-n74m5ucs 9 3 end end NN cord-345304-n74m5ucs 9 4 of of IN cord-345304-n74m5ucs 9 5 Abril Abril NNP cord-345304-n74m5ucs 9 6 , , , cord-345304-n74m5ucs 9 7 cases case NNS cord-345304-n74m5ucs 9 8 of of IN cord-345304-n74m5ucs 9 9 a a DT cord-345304-n74m5ucs 9 10 severe severe JJ cord-345304-n74m5ucs 9 11 rare rare JJ cord-345304-n74m5ucs 9 12 syndrome syndrome NN cord-345304-n74m5ucs 9 13 , , , cord-345304-n74m5ucs 9 14 temporally temporally RB cord-345304-n74m5ucs 9 15 associated associate VBN cord-345304-n74m5ucs 9 16 with with IN cord-345304-n74m5ucs 9 17 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 9 18 , , , cord-345304-n74m5ucs 9 19 have have VBP cord-345304-n74m5ucs 9 20 been be VBN cord-345304-n74m5ucs 9 21 reported report VBN cord-345304-n74m5ucs 9 22 in in IN cord-345304-n74m5ucs 9 23 children child NNS cord-345304-n74m5ucs 9 24 and and CC cord-345304-n74m5ucs 9 25 adolescents adolescent NNS cord-345304-n74m5ucs 9 26 , , , cord-345304-n74m5ucs 9 27 initially initially RB cord-345304-n74m5ucs 9 28 in in IN cord-345304-n74m5ucs 9 29 Europe Europe NNP cord-345304-n74m5ucs 9 30 and and CC cord-345304-n74m5ucs 9 31 then then RB cord-345304-n74m5ucs 9 32 in in IN cord-345304-n74m5ucs 9 33 North North NNP cord-345304-n74m5ucs 9 34 and and CC cord-345304-n74m5ucs 9 35 Latin Latin NNP cord-345304-n74m5ucs 9 36 America America NNP cord-345304-n74m5ucs 9 37 . . . cord-345304-n74m5ucs 10 1 This this DT cord-345304-n74m5ucs 10 2 syndrome syndrome NN cord-345304-n74m5ucs 10 3 , , , cord-345304-n74m5ucs 10 4 named name VBN cord-345304-n74m5ucs 10 5 multisystem multisystem JJ cord-345304-n74m5ucs 10 6 inflammatory inflammatory JJ cord-345304-n74m5ucs 10 7 syndrome syndrome NN cord-345304-n74m5ucs 10 8 in in IN cord-345304-n74m5ucs 10 9 children child NNS cord-345304-n74m5ucs 10 10 ( ( -LRB- cord-345304-n74m5ucs 10 11 MIS MIS NNP cord-345304-n74m5ucs 10 12 - - HYPH cord-345304-n74m5ucs 10 13 C C NNP cord-345304-n74m5ucs 10 14 ) ) -RRB- cord-345304-n74m5ucs 10 15 , , , cord-345304-n74m5ucs 10 16 occurs occur VBZ cord-345304-n74m5ucs 10 17 days day NNS cord-345304-n74m5ucs 10 18 to to IN cord-345304-n74m5ucs 10 19 weeks week NNS cord-345304-n74m5ucs 10 20 after after IN cord-345304-n74m5ucs 10 21 acute acute JJ cord-345304-n74m5ucs 10 22 SARS SARS NNP cord-345304-n74m5ucs 10 23 - - HYPH cord-345304-n74m5ucs 10 24 CoV-2 CoV-2 NNP cord-345304-n74m5ucs 10 25 infection infection NN cord-345304-n74m5ucs 10 26 . . . cord-345304-n74m5ucs 11 1 The the DT cord-345304-n74m5ucs 11 2 clinical clinical JJ cord-345304-n74m5ucs 11 3 characteristics characteristic NNS cord-345304-n74m5ucs 11 4 of of IN cord-345304-n74m5ucs 11 5 MIS MIS NNP cord-345304-n74m5ucs 11 6 - - HYPH cord-345304-n74m5ucs 11 7 C C NNP cord-345304-n74m5ucs 11 8 share share VBP cord-345304-n74m5ucs 11 9 similar similar JJ cord-345304-n74m5ucs 11 10 features feature NNS cord-345304-n74m5ucs 11 11 with with IN cord-345304-n74m5ucs 11 12 Kawasaki Kawasaki NNP cord-345304-n74m5ucs 11 13 disease disease NN cord-345304-n74m5ucs 11 14 ( ( -LRB- cord-345304-n74m5ucs 11 15 KD KD NNP cord-345304-n74m5ucs 11 16 ) ) -RRB- cord-345304-n74m5ucs 11 17 , , , cord-345304-n74m5ucs 11 18 KD KD NNP cord-345304-n74m5ucs 11 19 shock shock NN cord-345304-n74m5ucs 11 20 syndrome syndrome NN cord-345304-n74m5ucs 11 21 , , , cord-345304-n74m5ucs 11 22 macrophage macrophage NN cord-345304-n74m5ucs 11 23 activation activation NN cord-345304-n74m5ucs 11 24 syndrome syndrome NN cord-345304-n74m5ucs 11 25 ( ( -LRB- cord-345304-n74m5ucs 11 26 MAS MAS NNP cord-345304-n74m5ucs 11 27 ) ) -RRB- cord-345304-n74m5ucs 11 28 and and CC cord-345304-n74m5ucs 11 29 toxic toxic JJ cord-345304-n74m5ucs 11 30 shock shock NN cord-345304-n74m5ucs 11 31 syndrome syndrome NN cord-345304-n74m5ucs 11 32 . . . cord-345304-n74m5ucs 12 1 Although although IN cord-345304-n74m5ucs 12 2 many many JJ cord-345304-n74m5ucs 12 3 patients patient NNS cord-345304-n74m5ucs 12 4 with with IN cord-345304-n74m5ucs 12 5 MIS MIS NNP cord-345304-n74m5ucs 12 6 - - HYPH cord-345304-n74m5ucs 12 7 C C NNP cord-345304-n74m5ucs 12 8 meet meet VBP cord-345304-n74m5ucs 12 9 criteria criterion NNS cord-345304-n74m5ucs 12 10 for for IN cord-345304-n74m5ucs 12 11 complete complete JJ cord-345304-n74m5ucs 12 12 or or CC cord-345304-n74m5ucs 12 13 incomplete incomplete JJ cord-345304-n74m5ucs 12 14 KD KD NNP cord-345304-n74m5ucs 12 15 , , , cord-345304-n74m5ucs 12 16 affected affect VBN cord-345304-n74m5ucs 12 17 children child NNS cord-345304-n74m5ucs 12 18 were be VBD cord-345304-n74m5ucs 12 19 older old JJR cord-345304-n74m5ucs 12 20 , , , cord-345304-n74m5ucs 12 21 presented present VBD cord-345304-n74m5ucs 12 22 more more RBR cord-345304-n74m5ucs 12 23 intense intense JJ cord-345304-n74m5ucs 12 24 inflammation inflammation NN cord-345304-n74m5ucs 12 25 and and CC cord-345304-n74m5ucs 12 26 higher high JJR cord-345304-n74m5ucs 12 27 levels level NNS cord-345304-n74m5ucs 12 28 of of IN cord-345304-n74m5ucs 12 29 markers marker NNS cord-345304-n74m5ucs 12 30 of of IN cord-345304-n74m5ucs 12 31 cardiac cardiac JJ cord-345304-n74m5ucs 12 32 injury injury NN cord-345304-n74m5ucs 12 33 . . . cord-345304-n74m5ucs 13 1 A a DT cord-345304-n74m5ucs 13 2 broad broad JJ cord-345304-n74m5ucs 13 3 spectrum spectrum NN cord-345304-n74m5ucs 13 4 of of IN cord-345304-n74m5ucs 13 5 presenting present VBG cord-345304-n74m5ucs 13 6 signs sign NNS cord-345304-n74m5ucs 13 7 and and CC cord-345304-n74m5ucs 13 8 symptoms symptom NNS cord-345304-n74m5ucs 13 9 and and CC cord-345304-n74m5ucs 13 10 disease disease NN cord-345304-n74m5ucs 13 11 severity severity NN cord-345304-n74m5ucs 13 12 were be VBD cord-345304-n74m5ucs 13 13 observed observe VBN cord-345304-n74m5ucs 13 14 among among IN cord-345304-n74m5ucs 13 15 reported report VBN cord-345304-n74m5ucs 13 16 MIS MIS NNP cord-345304-n74m5ucs 13 17 - - HYPH cord-345304-n74m5ucs 13 18 C C NNP cord-345304-n74m5ucs 13 19 cases case NNS cord-345304-n74m5ucs 13 20 , , , cord-345304-n74m5ucs 13 21 including include VBG cord-345304-n74m5ucs 13 22 persistent persistent JJ cord-345304-n74m5ucs 13 23 fever fever NN cord-345304-n74m5ucs 13 24 , , , cord-345304-n74m5ucs 13 25 gastrointestinal gastrointestinal JJ cord-345304-n74m5ucs 13 26 symptoms symptom NNS cord-345304-n74m5ucs 13 27 ( ( -LRB- cord-345304-n74m5ucs 13 28 abdominal abdominal JJ cord-345304-n74m5ucs 13 29 pain pain NN cord-345304-n74m5ucs 13 30 , , , cord-345304-n74m5ucs 13 31 vomiting vomiting NN cord-345304-n74m5ucs 13 32 , , , cord-345304-n74m5ucs 13 33 diarrhea diarrhea NN cord-345304-n74m5ucs 13 34 ) ) -RRB- cord-345304-n74m5ucs 13 35 , , , cord-345304-n74m5ucs 13 36 rash rash JJ cord-345304-n74m5ucs 13 37 , , , cord-345304-n74m5ucs 13 38 conjunctivitis conjunctivitis NN cord-345304-n74m5ucs 13 39 , , , cord-345304-n74m5ucs 13 40 progressing progress VBG cord-345304-n74m5ucs 13 41 in in IN cord-345304-n74m5ucs 13 42 some some DT cord-345304-n74m5ucs 13 43 cases case NNS cord-345304-n74m5ucs 13 44 to to TO cord-345304-n74m5ucs 13 45 shock shock VB cord-345304-n74m5ucs 13 46 , , , cord-345304-n74m5ucs 13 47 myocarditis myocarditis NN cord-345304-n74m5ucs 13 48 , , , cord-345304-n74m5ucs 13 49 acute acute JJ cord-345304-n74m5ucs 13 50 heart heart NN cord-345304-n74m5ucs 13 51 failure failure NN cord-345304-n74m5ucs 13 52 and and CC cord-345304-n74m5ucs 13 53 development development NN cord-345304-n74m5ucs 13 54 of of IN cord-345304-n74m5ucs 13 55 coronary coronary JJ cord-345304-n74m5ucs 13 56 artery artery NN cord-345304-n74m5ucs 13 57 aneurysms aneurysm NNS cord-345304-n74m5ucs 13 58 . . . cord-345304-n74m5ucs 14 1 Patients patient NNS cord-345304-n74m5ucs 14 2 who who WP cord-345304-n74m5ucs 14 3 have have VBP cord-345304-n74m5ucs 14 4 presented present VBN cord-345304-n74m5ucs 14 5 with with IN cord-345304-n74m5ucs 14 6 this this DT cord-345304-n74m5ucs 14 7 syndrome syndrome NN cord-345304-n74m5ucs 14 8 were be VBD cord-345304-n74m5ucs 14 9 , , , cord-345304-n74m5ucs 14 10 in in IN cord-345304-n74m5ucs 14 11 general general JJ cord-345304-n74m5ucs 14 12 , , , cord-345304-n74m5ucs 14 13 previously previously RB cord-345304-n74m5ucs 14 14 healthy healthy JJ cord-345304-n74m5ucs 14 15 , , , cord-345304-n74m5ucs 14 16 and and CC cord-345304-n74m5ucs 14 17 most most JJS cord-345304-n74m5ucs 14 18 of of IN cord-345304-n74m5ucs 14 19 them -PRON- PRP cord-345304-n74m5ucs 14 20 have have VBP cord-345304-n74m5ucs 14 21 tested test VBN cord-345304-n74m5ucs 14 22 negative negative JJ cord-345304-n74m5ucs 14 23 for for IN cord-345304-n74m5ucs 14 24 SARS SARS NNP cord-345304-n74m5ucs 14 25 - - HYPH cord-345304-n74m5ucs 14 26 CoV-2 CoV-2 NNP cord-345304-n74m5ucs 14 27 RNA RNA NNP cord-345304-n74m5ucs 14 28 but but CC cord-345304-n74m5ucs 14 29 positive positive JJ cord-345304-n74m5ucs 14 30 for for IN cord-345304-n74m5ucs 14 31 antibodies antibody NNS cord-345304-n74m5ucs 14 32 , , , cord-345304-n74m5ucs 14 33 suggesting suggest VBG cord-345304-n74m5ucs 14 34 an an DT cord-345304-n74m5ucs 14 35 unbalanced unbalanced JJ cord-345304-n74m5ucs 14 36 immune immune JJ cord-345304-n74m5ucs 14 37 response response NN cord-345304-n74m5ucs 14 38 following follow VBG cord-345304-n74m5ucs 14 39 SARS SARS NNP cord-345304-n74m5ucs 14 40 - - HYPH cord-345304-n74m5ucs 14 41 CoV-2 CoV-2 NNP cord-345304-n74m5ucs 14 42 infection infection NN cord-345304-n74m5ucs 14 43 . . . cord-345304-n74m5ucs 15 1 Laboratory laboratory NN cord-345304-n74m5ucs 15 2 findings finding NNS cord-345304-n74m5ucs 15 3 include include VBP cord-345304-n74m5ucs 15 4 lymphocytopenia lymphocytopenia NNP cord-345304-n74m5ucs 15 5 , , , cord-345304-n74m5ucs 15 6 increased increase VBN cord-345304-n74m5ucs 15 7 inflammatory inflammatory JJ cord-345304-n74m5ucs 15 8 ( ( -LRB- cord-345304-n74m5ucs 15 9 C c NN cord-345304-n74m5ucs 15 10 - - HYPH cord-345304-n74m5ucs 15 11 reactive reactive JJ cord-345304-n74m5ucs 15 12 protein protein NN cord-345304-n74m5ucs 15 13 , , , cord-345304-n74m5ucs 15 14 erythrocyte erythrocyte NN cord-345304-n74m5ucs 15 15 sedimentation sedimentation NN cord-345304-n74m5ucs 15 16 rate rate NN cord-345304-n74m5ucs 15 17 , , , cord-345304-n74m5ucs 15 18 D d NN cord-345304-n74m5ucs 15 19 - - HYPH cord-345304-n74m5ucs 15 20 dimer dimer NN cord-345304-n74m5ucs 15 21 , , , cord-345304-n74m5ucs 15 22 ferritin ferritin NN cord-345304-n74m5ucs 15 23 ) ) -RRB- cord-345304-n74m5ucs 15 24 and and CC cord-345304-n74m5ucs 15 25 cardiac cardiac JJ cord-345304-n74m5ucs 15 26 biomarkers biomarker NNS cord-345304-n74m5ucs 15 27 ( ( -LRB- cord-345304-n74m5ucs 15 28 troponin troponin JJ cord-345304-n74m5ucs 15 29 , , , cord-345304-n74m5ucs 15 30 brain brain NN cord-345304-n74m5ucs 15 31 natriuretic natriuretic JJ cord-345304-n74m5ucs 15 32 peptide peptide NN cord-345304-n74m5ucs 15 33 [ [ -LRB- cord-345304-n74m5ucs 15 34 BNP BNP NNP cord-345304-n74m5ucs 15 35 ] ] -RRB- cord-345304-n74m5ucs 15 36 ) ) -RRB- cord-345304-n74m5ucs 15 37 . . . cord-345304-n74m5ucs 16 1 6 6 CD cord-345304-n74m5ucs 17 1 Based base VBN cord-345304-n74m5ucs 17 2 on on IN cord-345304-n74m5ucs 17 3 current current JJ cord-345304-n74m5ucs 17 4 evidence evidence NN cord-345304-n74m5ucs 17 5 , , , cord-345304-n74m5ucs 17 6 older old JJR cord-345304-n74m5ucs 17 7 adults adult NNS cord-345304-n74m5ucs 17 8 and and CC cord-345304-n74m5ucs 17 9 people people NNS cord-345304-n74m5ucs 17 10 of of IN cord-345304-n74m5ucs 17 11 all all DT cord-345304-n74m5ucs 17 12 ages age NNS cord-345304-n74m5ucs 17 13 with with IN cord-345304-n74m5ucs 17 14 underlying underlying JJ cord-345304-n74m5ucs 17 15 medical medical JJ cord-345304-n74m5ucs 17 16 conditions condition NNS cord-345304-n74m5ucs 17 17 , , , cord-345304-n74m5ucs 17 18 including include VBG cord-345304-n74m5ucs 17 19 severe severe JJ cord-345304-n74m5ucs 17 20 obesity obesity NN cord-345304-n74m5ucs 17 21 , , , cord-345304-n74m5ucs 17 22 chronic chronic JJ cord-345304-n74m5ucs 17 23 lung lung NN cord-345304-n74m5ucs 17 24 disease disease NN cord-345304-n74m5ucs 17 25 , , , cord-345304-n74m5ucs 17 26 cardiovascular cardiovascular JJ cord-345304-n74m5ucs 17 27 disease disease NN cord-345304-n74m5ucs 17 28 , , , cord-345304-n74m5ucs 17 29 diabetes diabetes NN cord-345304-n74m5ucs 17 30 mellitus mellitus NN cord-345304-n74m5ucs 17 31 , , , cord-345304-n74m5ucs 17 32 chronic chronic JJ cord-345304-n74m5ucs 17 33 kidney kidney NN cord-345304-n74m5ucs 17 34 disease disease NN cord-345304-n74m5ucs 17 35 , , , cord-345304-n74m5ucs 17 36 liver liver NN cord-345304-n74m5ucs 17 37 disease disease NN cord-345304-n74m5ucs 17 38 , , , cord-345304-n74m5ucs 17 39 active active JJ cord-345304-n74m5ucs 17 40 cancer cancer NN cord-345304-n74m5ucs 17 41 , , , cord-345304-n74m5ucs 17 42 transplantation transplantation NN cord-345304-n74m5ucs 17 43 and and CC cord-345304-n74m5ucs 17 44 immunocompromised immunocompromised JJ cord-345304-n74m5ucs 17 45 have have VBP cord-345304-n74m5ucs 17 46 been be VBN cord-345304-n74m5ucs 17 47 associated associate VBN cord-345304-n74m5ucs 17 48 with with IN cord-345304-n74m5ucs 17 49 poor poor JJ cord-345304-n74m5ucs 17 50 clinical clinical JJ cord-345304-n74m5ucs 17 51 outcomes outcome NNS cord-345304-n74m5ucs 17 52 and and CC cord-345304-n74m5ucs 17 53 higher high JJR cord-345304-n74m5ucs 17 54 fatality fatality NN cord-345304-n74m5ucs 17 55 rates rate NNS cord-345304-n74m5ucs 17 56 from from IN cord-345304-n74m5ucs 17 57 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 17 58 . . NNP cord-345304-n74m5ucs 17 59 1 1 CD cord-345304-n74m5ucs 17 60 , , , cord-345304-n74m5ucs 17 61 3 3 CD cord-345304-n74m5ucs 17 62 There there EX cord-345304-n74m5ucs 17 63 are be VBP cord-345304-n74m5ucs 17 64 limited limited JJ cord-345304-n74m5ucs 17 65 data datum NNS cord-345304-n74m5ucs 17 66 on on IN cord-345304-n74m5ucs 17 67 which which WDT cord-345304-n74m5ucs 17 68 underlying underlie VBG cord-345304-n74m5ucs 17 69 conditions condition NNS cord-345304-n74m5ucs 17 70 in in IN cord-345304-n74m5ucs 17 71 children child NNS cord-345304-n74m5ucs 17 72 and and CC cord-345304-n74m5ucs 17 73 adolescents adolescent NNS cord-345304-n74m5ucs 17 74 are be VBP cord-345304-n74m5ucs 17 75 associated associate VBN cord-345304-n74m5ucs 17 76 with with IN cord-345304-n74m5ucs 17 77 increased increase VBN cord-345304-n74m5ucs 17 78 risk risk NN cord-345304-n74m5ucs 17 79 of of IN cord-345304-n74m5ucs 17 80 infection infection NN cord-345304-n74m5ucs 17 81 or or CC cord-345304-n74m5ucs 17 82 severe severe JJ cord-345304-n74m5ucs 17 83 illness illness NN cord-345304-n74m5ucs 17 84 . . . cord-345304-n74m5ucs 18 1 Infants infant NNS cord-345304-n74m5ucs 18 2 < < XX cord-345304-n74m5ucs 18 3 1 1 CD cord-345304-n74m5ucs 18 4 year year NN cord-345304-n74m5ucs 18 5 of of IN cord-345304-n74m5ucs 18 6 age age NN cord-345304-n74m5ucs 18 7 and and CC cord-345304-n74m5ucs 18 8 children child NNS cord-345304-n74m5ucs 18 9 with with IN cord-345304-n74m5ucs 18 10 chronic chronic JJ cord-345304-n74m5ucs 18 11 pulmonary pulmonary JJ cord-345304-n74m5ucs 18 12 diseases disease NNS cord-345304-n74m5ucs 18 13 ( ( -LRB- cord-345304-n74m5ucs 18 14 including include VBG cord-345304-n74m5ucs 18 15 moderate moderate JJ cord-345304-n74m5ucs 18 16 to to IN cord-345304-n74m5ucs 18 17 severe severe JJ cord-345304-n74m5ucs 18 18 asthma asthma NN cord-345304-n74m5ucs 18 19 ) ) -RRB- cord-345304-n74m5ucs 18 20 , , , cord-345304-n74m5ucs 18 21 cardiovascular cardiovascular JJ cord-345304-n74m5ucs 18 22 illnesses illness NNS cord-345304-n74m5ucs 18 23 ( ( -LRB- cord-345304-n74m5ucs 18 24 including include VBG cord-345304-n74m5ucs 18 25 congenital congenital JJ cord-345304-n74m5ucs 18 26 heart heart NN cord-345304-n74m5ucs 18 27 disease disease NN cord-345304-n74m5ucs 18 28 ) ) -RRB- cord-345304-n74m5ucs 18 29 , , , cord-345304-n74m5ucs 18 30 malignancy malignancy NN cord-345304-n74m5ucs 18 31 , , , cord-345304-n74m5ucs 18 32 immunosuppression immunosuppression NN cord-345304-n74m5ucs 18 33 and and CC cord-345304-n74m5ucs 18 34 obesity obesity NN cord-345304-n74m5ucs 18 35 appear appear VBP cord-345304-n74m5ucs 18 36 to to TO cord-345304-n74m5ucs 18 37 be be VB cord-345304-n74m5ucs 18 38 at at IN cord-345304-n74m5ucs 18 39 increased increase VBN cord-345304-n74m5ucs 18 40 risk risk NN cord-345304-n74m5ucs 18 41 of of IN cord-345304-n74m5ucs 18 42 severe severe JJ cord-345304-n74m5ucs 18 43 disease disease NN cord-345304-n74m5ucs 18 44 . . . cord-345304-n74m5ucs 19 1 [ [ -LRB- cord-345304-n74m5ucs 19 2 8 8 CD cord-345304-n74m5ucs 19 3 ] ] -RRB- cord-345304-n74m5ucs 19 4 [ [ -LRB- cord-345304-n74m5ucs 19 5 9 9 CD cord-345304-n74m5ucs 19 6 ] ] -RRB- cord-345304-n74m5ucs 19 7 [ [ -LRB- cord-345304-n74m5ucs 19 8 10 10 CD cord-345304-n74m5ucs 19 9 ] ] -RRB- cord-345304-n74m5ucs 19 10 Data datum NNS cord-345304-n74m5ucs 19 11 of of IN cord-345304-n74m5ucs 19 12 immunocompromised immunocompromised JJ cord-345304-n74m5ucs 19 13 patients patient NNS cord-345304-n74m5ucs 19 14 with with IN cord-345304-n74m5ucs 19 15 autoimmune autoimmune JJ cord-345304-n74m5ucs 19 16 diseases disease NNS cord-345304-n74m5ucs 19 17 and and CC cord-345304-n74m5ucs 19 18 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 19 19 are be VBP cord-345304-n74m5ucs 19 20 scarce scarce JJ cord-345304-n74m5ucs 19 21 . . . cord-345304-n74m5ucs 20 1 Although although IN cord-345304-n74m5ucs 20 2 the the DT cord-345304-n74m5ucs 20 3 true true JJ cord-345304-n74m5ucs 20 4 risk risk NN cord-345304-n74m5ucs 20 5 of of IN cord-345304-n74m5ucs 20 6 life life NN cord-345304-n74m5ucs 20 7 - - HYPH cord-345304-n74m5ucs 20 8 threatening threaten VBG cord-345304-n74m5ucs 20 9 complications complication NNS cord-345304-n74m5ucs 20 10 of of IN cord-345304-n74m5ucs 20 11 this this DT cord-345304-n74m5ucs 20 12 emerging emerge VBG cord-345304-n74m5ucs 20 13 infectious infectious JJ cord-345304-n74m5ucs 20 14 disease disease NN cord-345304-n74m5ucs 20 15 for for IN cord-345304-n74m5ucs 20 16 these these DT cord-345304-n74m5ucs 20 17 chronic chronic JJ cord-345304-n74m5ucs 20 18 illnesses illness NNS cord-345304-n74m5ucs 20 19 is be VBZ cord-345304-n74m5ucs 20 20 not not RB cord-345304-n74m5ucs 20 21 yet yet RB cord-345304-n74m5ucs 20 22 known know VBN cord-345304-n74m5ucs 20 23 , , , cord-345304-n74m5ucs 20 24 there there EX cord-345304-n74m5ucs 20 25 are be VBP cord-345304-n74m5ucs 20 26 particular particular JJ cord-345304-n74m5ucs 20 27 concerns concern NNS cord-345304-n74m5ucs 20 28 regarding regard VBG cord-345304-n74m5ucs 20 29 SARS SARS NNP cord-345304-n74m5ucs 20 30 - - HYPH cord-345304-n74m5ucs 20 31 CoV-2 CoV-2 NNP cord-345304-n74m5ucs 20 32 infection infection NN cord-345304-n74m5ucs 20 33 for for IN cord-345304-n74m5ucs 20 34 patients patient NNS cord-345304-n74m5ucs 20 35 treated treat VBN cord-345304-n74m5ucs 20 36 with with IN cord-345304-n74m5ucs 20 37 immunosuppressive immunosuppressive JJ cord-345304-n74m5ucs 20 38 , , , cord-345304-n74m5ucs 20 39 biological biological JJ cord-345304-n74m5ucs 20 40 agents agent NNS cord-345304-n74m5ucs 20 41 and and CC cord-345304-n74m5ucs 20 42 disease disease NN cord-345304-n74m5ucs 20 43 - - HYPH cord-345304-n74m5ucs 20 44 modifying modify VBG cord-345304-n74m5ucs 20 45 antirheumatic antirheumatic JJ cord-345304-n74m5ucs 20 46 drugs drug NNS cord-345304-n74m5ucs 20 47 . . . cord-345304-n74m5ucs 21 1 11 11 CD cord-345304-n74m5ucs 21 2 One one CD cord-345304-n74m5ucs 21 3 of of IN cord-345304-n74m5ucs 21 4 the the DT cord-345304-n74m5ucs 21 5 most most RBS cord-345304-n74m5ucs 21 6 important important JJ cord-345304-n74m5ucs 21 7 Latin latin JJ cord-345304-n74m5ucs 21 8 American american JJ cord-345304-n74m5ucs 21 9 reference reference NN cord-345304-n74m5ucs 21 10 centers center NNS cord-345304-n74m5ucs 21 11 for for IN cord-345304-n74m5ucs 21 12 pediatric pediatric JJ cord-345304-n74m5ucs 21 13 liver liver NN cord-345304-n74m5ucs 21 14 diseases disease NNS cord-345304-n74m5ucs 21 15 and and CC cord-345304-n74m5ucs 21 16 pediatric pediatric JJ cord-345304-n74m5ucs 21 17 liver liver NN cord-345304-n74m5ucs 21 18 transplantation transplantation NN cord-345304-n74m5ucs 21 19 in in IN cord-345304-n74m5ucs 21 20 Brazil Brazil NNP cord-345304-n74m5ucs 21 21 described describe VBD cord-345304-n74m5ucs 21 22 their -PRON- PRP$ cord-345304-n74m5ucs 21 23 experience experience NN cord-345304-n74m5ucs 21 24 with with IN cord-345304-n74m5ucs 21 25 169 169 CD cord-345304-n74m5ucs 21 26 non non JJ cord-345304-n74m5ucs 21 27 - - JJ cord-345304-n74m5ucs 21 28 transplant transplant JJ cord-345304-n74m5ucs 21 29 children child NNS cord-345304-n74m5ucs 21 30 and and CC cord-345304-n74m5ucs 21 31 adolescents adolescent NNS cord-345304-n74m5ucs 21 32 suspected suspect VBN cord-345304-n74m5ucs 21 33 and and CC cord-345304-n74m5ucs 21 34 tested test VBN cord-345304-n74m5ucs 21 35 for for IN cord-345304-n74m5ucs 21 36 SARS SARS NNP cord-345304-n74m5ucs 21 37 - - HYPH cord-345304-n74m5ucs 21 38 CoV-2 CoV-2 NNP cord-345304-n74m5ucs 21 39 . . . cord-345304-n74m5ucs 22 1 Of of IN cord-345304-n74m5ucs 22 2 note note NN cord-345304-n74m5ucs 22 3 , , , cord-345304-n74m5ucs 22 4 13/169 13/169 CD cord-345304-n74m5ucs 22 5 ( ( -LRB- cord-345304-n74m5ucs 22 6 8 8 CD cord-345304-n74m5ucs 22 7 % % NN cord-345304-n74m5ucs 22 8 ) ) -RRB- cord-345304-n74m5ucs 22 9 of of IN cord-345304-n74m5ucs 22 10 them -PRON- PRP cord-345304-n74m5ucs 22 11 had have VBD cord-345304-n74m5ucs 22 12 laboratory laboratory NN cord-345304-n74m5ucs 22 13 - - HYPH cord-345304-n74m5ucs 22 14 confirmed confirm VBN cord-345304-n74m5ucs 22 15 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 22 16 . . . cord-345304-n74m5ucs 23 1 All all DT cord-345304-n74m5ucs 23 2 of of IN cord-345304-n74m5ucs 23 3 them -PRON- PRP cord-345304-n74m5ucs 23 4 had have VBD cord-345304-n74m5ucs 23 5 mild mild JJ cord-345304-n74m5ucs 23 6 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 23 7 , , , cord-345304-n74m5ucs 23 8 except except IN cord-345304-n74m5ucs 23 9 one one CD cord-345304-n74m5ucs 23 10 that that WDT cord-345304-n74m5ucs 23 11 died die VBD cord-345304-n74m5ucs 23 12 due due JJ cord-345304-n74m5ucs 23 13 to to IN cord-345304-n74m5ucs 23 14 a a DT cord-345304-n74m5ucs 23 15 serious serious JJ cord-345304-n74m5ucs 23 16 genetic genetic JJ cord-345304-n74m5ucs 23 17 syndrome syndrome NN cord-345304-n74m5ucs 23 18 . . . cord-345304-n74m5ucs 24 1 Furthermore furthermore RB cord-345304-n74m5ucs 24 2 , , , cord-345304-n74m5ucs 24 3 during during IN cord-345304-n74m5ucs 24 4 the the DT cord-345304-n74m5ucs 24 5 study study NN cord-345304-n74m5ucs 24 6 period period NN cord-345304-n74m5ucs 24 7 , , , cord-345304-n74m5ucs 24 8 none none NN cord-345304-n74m5ucs 24 9 of of IN cord-345304-n74m5ucs 24 10 190 190 CD cord-345304-n74m5ucs 24 11 pediatric pediatric JJ cord-345304-n74m5ucs 24 12 liver liver NN cord-345304-n74m5ucs 24 13 transplant transplant NN cord-345304-n74m5ucs 24 14 patients patient NNS cord-345304-n74m5ucs 24 15 had have VBD cord-345304-n74m5ucs 24 16 COVID-19 COVID-19 VBN cord-345304-n74m5ucs 24 17 . . . cord-345304-n74m5ucs 24 18 12 12 CD cord-345304-n74m5ucs 24 19 Overall overall JJ cord-345304-n74m5ucs 24 20 morbidity morbidity NN cord-345304-n74m5ucs 24 21 and and CC cord-345304-n74m5ucs 24 22 mortality mortality NN cord-345304-n74m5ucs 24 23 of of IN cord-345304-n74m5ucs 24 24 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 24 25 in in IN cord-345304-n74m5ucs 24 26 pediatric pediatric JJ cord-345304-n74m5ucs 24 27 patients patient NNS cord-345304-n74m5ucs 24 28 with with IN cord-345304-n74m5ucs 24 29 cancer cancer NN cord-345304-n74m5ucs 24 30 seem seem VBP cord-345304-n74m5ucs 24 31 to to TO cord-345304-n74m5ucs 24 32 be be VB cord-345304-n74m5ucs 24 33 low low JJ cord-345304-n74m5ucs 24 34 . . . cord-345304-n74m5ucs 25 1 One one CD cord-345304-n74m5ucs 25 2 of of IN cord-345304-n74m5ucs 25 3 the the DT cord-345304-n74m5ucs 25 4 largest large JJS cord-345304-n74m5ucs 25 5 pediatric pediatric JJ cord-345304-n74m5ucs 25 6 cancer cancer NN cord-345304-n74m5ucs 25 7 programs program NNS cord-345304-n74m5ucs 25 8 in in IN cord-345304-n74m5ucs 25 9 the the DT cord-345304-n74m5ucs 25 10 USA USA NNP cord-345304-n74m5ucs 25 11 , , , cord-345304-n74m5ucs 25 12 in in IN cord-345304-n74m5ucs 25 13 New New NNP cord-345304-n74m5ucs 25 14 York York NNP cord-345304-n74m5ucs 25 15 city city NN cord-345304-n74m5ucs 25 16 , , , cord-345304-n74m5ucs 25 17 reported report VBD cord-345304-n74m5ucs 25 18 that that IN cord-345304-n74m5ucs 25 19 20/178 20/178 CD cord-345304-n74m5ucs 25 20 ( ( -LRB- cord-345304-n74m5ucs 25 21 11 11 CD cord-345304-n74m5ucs 25 22 % % NN cord-345304-n74m5ucs 25 23 ) ) -RRB- cord-345304-n74m5ucs 25 24 children child NNS cord-345304-n74m5ucs 25 25 and and CC cord-345304-n74m5ucs 25 26 adolescents adolescent NNS cord-345304-n74m5ucs 25 27 with with IN cord-345304-n74m5ucs 25 28 cancer cancer NN cord-345304-n74m5ucs 25 29 had have VBD cord-345304-n74m5ucs 25 30 positive positive JJ cord-345304-n74m5ucs 25 31 test test NN cord-345304-n74m5ucs 25 32 for for IN cord-345304-n74m5ucs 25 33 SARS SARS NNP cord-345304-n74m5ucs 25 34 - - HYPH cord-345304-n74m5ucs 25 35 CoV-2 CoV-2 NNP cord-345304-n74m5ucs 25 36 . . . cord-345304-n74m5ucs 26 1 Only only RB cord-345304-n74m5ucs 26 2 one one CD cord-345304-n74m5ucs 26 3 patient patient NN cord-345304-n74m5ucs 26 4 with with IN cord-345304-n74m5ucs 26 5 COVID-19 covid-19 CC cord-345304-n74m5ucs 26 6 required require VBN cord-345304-n74m5ucs 26 7 noncritical noncritical JJ cord-345304-n74m5ucs 26 8 hospitalization hospitalization NN cord-345304-n74m5ucs 26 9 . . . cord-345304-n74m5ucs 27 1 13 13 CD cord-345304-n74m5ucs 27 2 Malignancy malignancy NN cord-345304-n74m5ucs 27 3 in in IN cord-345304-n74m5ucs 27 4 pediatric pediatric JJ cord-345304-n74m5ucs 27 5 populations population NNS cord-345304-n74m5ucs 27 6 are be VBP cord-345304-n74m5ucs 27 7 generally generally RB cord-345304-n74m5ucs 27 8 aggressive aggressive JJ cord-345304-n74m5ucs 27 9 , , , cord-345304-n74m5ucs 27 10 needing need VBG cord-345304-n74m5ucs 27 11 multiple multiple JJ cord-345304-n74m5ucs 27 12 chemotherapy chemotherapy NN cord-345304-n74m5ucs 27 13 or or CC cord-345304-n74m5ucs 27 14 stem stem NN cord-345304-n74m5ucs 27 15 cell cell NN cord-345304-n74m5ucs 27 16 transplantation transplantation NN cord-345304-n74m5ucs 27 17 . . . cord-345304-n74m5ucs 28 1 Therefore therefore RB cord-345304-n74m5ucs 28 2 , , , cord-345304-n74m5ucs 28 3 postponing postpone VBG cord-345304-n74m5ucs 28 4 these these DT cord-345304-n74m5ucs 28 5 therapies therapy NNS cord-345304-n74m5ucs 28 6 are be VBP cord-345304-n74m5ucs 28 7 not not RB cord-345304-n74m5ucs 28 8 recommended recommend VBN cord-345304-n74m5ucs 28 9 during during IN cord-345304-n74m5ucs 28 10 COVID-19 covid-19 JJ cord-345304-n74m5ucs 28 11 pandemic pandemic NN cord-345304-n74m5ucs 28 12 . . . cord-345304-n74m5ucs 29 1 Importantly importantly RB cord-345304-n74m5ucs 29 2 , , , cord-345304-n74m5ucs 29 3 the the DT cord-345304-n74m5ucs 29 4 long long JJ cord-345304-n74m5ucs 29 5 - - HYPH cord-345304-n74m5ucs 29 6 term term NN cord-345304-n74m5ucs 29 7 effects effect NNS cord-345304-n74m5ucs 29 8 of of IN cord-345304-n74m5ucs 29 9 this this DT cord-345304-n74m5ucs 29 10 pandemic pandemic NN cord-345304-n74m5ucs 29 11 , , , cord-345304-n74m5ucs 29 12 with with IN cord-345304-n74m5ucs 29 13 school school NN cord-345304-n74m5ucs 29 14 closure closure NN cord-345304-n74m5ucs 29 15 and and CC cord-345304-n74m5ucs 29 16 social social JJ cord-345304-n74m5ucs 29 17 isolation isolation NN cord-345304-n74m5ucs 29 18 during during IN cord-345304-n74m5ucs 29 19 quarantine quarantine NN cord-345304-n74m5ucs 29 20 / / SYM cord-345304-n74m5ucs 29 21 lockdown lockdown NN cord-345304-n74m5ucs 29 22 for for IN cord-345304-n74m5ucs 29 23 children child NNS cord-345304-n74m5ucs 29 24 and and CC cord-345304-n74m5ucs 29 25 adolescents adolescent NNS cord-345304-n74m5ucs 29 26 , , , cord-345304-n74m5ucs 29 27 may may MD cord-345304-n74m5ucs 29 28 influence influence VB cord-345304-n74m5ucs 29 29 sedentary sedentary JJ cord-345304-n74m5ucs 29 30 behavior behavior NN cord-345304-n74m5ucs 29 31 and and CC cord-345304-n74m5ucs 29 32 consumption consumption NN cord-345304-n74m5ucs 29 33 of of IN cord-345304-n74m5ucs 29 34 calories calorie NNS cord-345304-n74m5ucs 29 35 - - HYPH cord-345304-n74m5ucs 29 36 dense dense JJ cord-345304-n74m5ucs 29 37 comfort comfort NN cord-345304-n74m5ucs 29 38 foods food NNS cord-345304-n74m5ucs 29 39 , , , cord-345304-n74m5ucs 29 40 increasing increase VBG cord-345304-n74m5ucs 29 41 the the DT cord-345304-n74m5ucs 29 42 risk risk NN cord-345304-n74m5ucs 29 43 of of IN cord-345304-n74m5ucs 29 44 weight weight NN cord-345304-n74m5ucs 29 45 gain gain NN cord-345304-n74m5ucs 29 46 and and CC cord-345304-n74m5ucs 29 47 contributing contribute VBG cord-345304-n74m5ucs 29 48 for for IN cord-345304-n74m5ucs 29 49 metabolic metabolic JJ cord-345304-n74m5ucs 29 50 and and CC cord-345304-n74m5ucs 29 51 cardiovascular cardiovascular JJ cord-345304-n74m5ucs 29 52 diseases disease NNS cord-345304-n74m5ucs 29 53 , , , cord-345304-n74m5ucs 29 54 particularly particularly RB cord-345304-n74m5ucs 29 55 among among IN cord-345304-n74m5ucs 29 56 those those DT cord-345304-n74m5ucs 29 57 living live VBG cord-345304-n74m5ucs 29 58 in in IN cord-345304-n74m5ucs 29 59 urban urban JJ cord-345304-n74m5ucs 29 60 districts district NNS cord-345304-n74m5ucs 29 61 . . . cord-345304-n74m5ucs 30 1 11 11 LS cord-345304-n74m5ucs 30 2 There there EX cord-345304-n74m5ucs 30 3 are be VBP cord-345304-n74m5ucs 30 4 other other JJ cord-345304-n74m5ucs 30 5 challenges challenge NNS cord-345304-n74m5ucs 30 6 related relate VBN cord-345304-n74m5ucs 30 7 to to IN cord-345304-n74m5ucs 30 8 this this DT cord-345304-n74m5ucs 30 9 pandemic pandemic NN cord-345304-n74m5ucs 30 10 in in IN cord-345304-n74m5ucs 30 11 children child NNS cord-345304-n74m5ucs 30 12 and and CC cord-345304-n74m5ucs 30 13 adolescents adolescent NNS cord-345304-n74m5ucs 30 14 . . . cord-345304-n74m5ucs 31 1 Non non JJ cord-345304-n74m5ucs 31 2 - - JJ cord-345304-n74m5ucs 31 3 pharmacological pharmacological JJ cord-345304-n74m5ucs 31 4 interventions intervention NNS cord-345304-n74m5ucs 31 5 have have VBP cord-345304-n74m5ucs 31 6 been be VBN cord-345304-n74m5ucs 31 7 an an DT cord-345304-n74m5ucs 31 8 essential essential JJ cord-345304-n74m5ucs 31 9 preventive preventive JJ cord-345304-n74m5ucs 31 10 measure measure NN cord-345304-n74m5ucs 31 11 , , , cord-345304-n74m5ucs 31 12 recommended recommend VBN cord-345304-n74m5ucs 31 13 by by IN cord-345304-n74m5ucs 31 14 national national JJ cord-345304-n74m5ucs 31 15 and and CC cord-345304-n74m5ucs 31 16 international international JJ cord-345304-n74m5ucs 31 17 public public JJ cord-345304-n74m5ucs 31 18 health health NN cord-345304-n74m5ucs 31 19 authorities authority NNS cord-345304-n74m5ucs 31 20 . . . cord-345304-n74m5ucs 32 1 Besides besides IN cord-345304-n74m5ucs 32 2 the the DT cord-345304-n74m5ucs 32 3 risk risk NN cord-345304-n74m5ucs 32 4 of of IN cord-345304-n74m5ucs 32 5 limited limited JJ cord-345304-n74m5ucs 32 6 or or CC cord-345304-n74m5ucs 32 7 even even RB cord-345304-n74m5ucs 32 8 no no DT cord-345304-n74m5ucs 32 9 education education NN cord-345304-n74m5ucs 32 10 for for IN cord-345304-n74m5ucs 32 11 children child NNS cord-345304-n74m5ucs 32 12 and and CC cord-345304-n74m5ucs 32 13 adolescents adolescent NNS cord-345304-n74m5ucs 32 14 during during IN cord-345304-n74m5ucs 32 15 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 32 16 crisis crisis NN cord-345304-n74m5ucs 32 17 , , , cord-345304-n74m5ucs 32 18 home home NN cord-345304-n74m5ucs 32 19 confinements confinement NNS cord-345304-n74m5ucs 32 20 may may MD cord-345304-n74m5ucs 32 21 induce induce VB cord-345304-n74m5ucs 32 22 longer long JJR cord-345304-n74m5ucs 32 23 screen screen NN cord-345304-n74m5ucs 32 24 time time NN cord-345304-n74m5ucs 32 25 , , , cord-345304-n74m5ucs 32 26 physical physical JJ cord-345304-n74m5ucs 32 27 inactivity inactivity NN cord-345304-n74m5ucs 32 28 , , , cord-345304-n74m5ucs 32 29 sleep sleep NN cord-345304-n74m5ucs 32 30 abnormalities abnormality NNS cord-345304-n74m5ucs 32 31 , , , cord-345304-n74m5ucs 32 32 increase increase VBP cord-345304-n74m5ucs 32 33 alcohol alcohol NN cord-345304-n74m5ucs 32 34 intake intake NN cord-345304-n74m5ucs 32 35 risk risk NN cord-345304-n74m5ucs 32 36 and and CC cord-345304-n74m5ucs 32 37 domestic domestic JJ cord-345304-n74m5ucs 32 38 violence violence NN cord-345304-n74m5ucs 32 39 , , , cord-345304-n74m5ucs 32 40 particularly particularly RB cord-345304-n74m5ucs 32 41 in in IN cord-345304-n74m5ucs 32 42 adolescents adolescent NNS cord-345304-n74m5ucs 32 43 . . . cord-345304-n74m5ucs 33 1 Drug drug NN cord-345304-n74m5ucs 33 2 adherence adherence NN cord-345304-n74m5ucs 33 3 should should MD cord-345304-n74m5ucs 33 4 also also RB cord-345304-n74m5ucs 33 5 be be VB cord-345304-n74m5ucs 33 6 reinforced reinforce VBN cord-345304-n74m5ucs 33 7 for for IN cord-345304-n74m5ucs 33 8 patients patient NNS cord-345304-n74m5ucs 33 9 with with IN cord-345304-n74m5ucs 33 10 preexisting preexist VBG cord-345304-n74m5ucs 33 11 chronic chronic JJ cord-345304-n74m5ucs 33 12 disease disease NN cord-345304-n74m5ucs 33 13 and and CC cord-345304-n74m5ucs 33 14 their -PRON- PRP$ cord-345304-n74m5ucs 33 15 families family NNS cord-345304-n74m5ucs 33 16 due due JJ cord-345304-n74m5ucs 33 17 to to IN cord-345304-n74m5ucs 33 18 risk risk NN cord-345304-n74m5ucs 33 19 of of IN cord-345304-n74m5ucs 33 20 disease disease NN cord-345304-n74m5ucs 33 21 flare flare NN cord-345304-n74m5ucs 33 22 or or CC cord-345304-n74m5ucs 33 23 disease disease NN cord-345304-n74m5ucs 33 24 damage damage NN cord-345304-n74m5ucs 33 25 . . . cord-345304-n74m5ucs 34 1 Patients patient NNS cord-345304-n74m5ucs 34 2 with with IN cord-345304-n74m5ucs 34 3 suspected suspect VBN cord-345304-n74m5ucs 34 4 or or CC cord-345304-n74m5ucs 34 5 confirmed confirm VBN cord-345304-n74m5ucs 34 6 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 34 7 must must MD cord-345304-n74m5ucs 34 8 be be VB cord-345304-n74m5ucs 34 9 strictly strictly RB cord-345304-n74m5ucs 34 10 monitored monitor VBN cord-345304-n74m5ucs 34 11 for for IN cord-345304-n74m5ucs 34 12 the the DT cord-345304-n74m5ucs 34 13 possible possible JJ cord-345304-n74m5ucs 34 14 risk risk NN cord-345304-n74m5ucs 34 15 of of IN cord-345304-n74m5ucs 34 16 disease disease NN cord-345304-n74m5ucs 34 17 reactivation reactivation NN cord-345304-n74m5ucs 34 18 after after IN cord-345304-n74m5ucs 34 19 the the DT cord-345304-n74m5ucs 34 20 resolution resolution NN cord-345304-n74m5ucs 34 21 of of IN cord-345304-n74m5ucs 34 22 this this DT cord-345304-n74m5ucs 34 23 viral viral JJ cord-345304-n74m5ucs 34 24 infection infection NN cord-345304-n74m5ucs 34 25 . . . cord-345304-n74m5ucs 35 1 11 11 CD cord-345304-n74m5ucs 36 1 The the DT cord-345304-n74m5ucs 36 2 overwhelmed overwhelmed JJ cord-345304-n74m5ucs 36 3 public public JJ cord-345304-n74m5ucs 36 4 health health NN cord-345304-n74m5ucs 36 5 systems system NNS cord-345304-n74m5ucs 36 6 by by IN cord-345304-n74m5ucs 36 7 the the DT cord-345304-n74m5ucs 36 8 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 36 9 pandemic pandemic NN cord-345304-n74m5ucs 36 10 represents represent VBZ cord-345304-n74m5ucs 36 11 a a DT cord-345304-n74m5ucs 36 12 serious serious JJ cord-345304-n74m5ucs 36 13 risk risk NN cord-345304-n74m5ucs 36 14 for for IN cord-345304-n74m5ucs 36 15 pediatric pediatric JJ cord-345304-n74m5ucs 36 16 general general JJ cord-345304-n74m5ucs 36 17 health health NN cord-345304-n74m5ucs 36 18 , , , cord-345304-n74m5ucs 36 19 limiting limit VBG cord-345304-n74m5ucs 36 20 access access NN cord-345304-n74m5ucs 36 21 of of IN cord-345304-n74m5ucs 36 22 children child NNS cord-345304-n74m5ucs 36 23 and and CC cord-345304-n74m5ucs 36 24 adolescents adolescent NNS cord-345304-n74m5ucs 36 25 to to IN cord-345304-n74m5ucs 36 26 basic basic JJ cord-345304-n74m5ucs 36 27 health health NN cord-345304-n74m5ucs 36 28 care care NN cord-345304-n74m5ucs 36 29 , , , cord-345304-n74m5ucs 36 30 compromising compromise VBG cord-345304-n74m5ucs 36 31 immunization immunization NN cord-345304-n74m5ucs 36 32 coverages coverage NNS cord-345304-n74m5ucs 36 33 and and CC cord-345304-n74m5ucs 36 34 postponing postpone VBG cord-345304-n74m5ucs 36 35 consultations consultation NNS cord-345304-n74m5ucs 36 36 for for IN cord-345304-n74m5ucs 36 37 patients patient NNS cord-345304-n74m5ucs 36 38 with with IN cord-345304-n74m5ucs 36 39 underlying underlying JJ cord-345304-n74m5ucs 36 40 conditions condition NNS cord-345304-n74m5ucs 36 41 . . . cord-345304-n74m5ucs 37 1 Moreover moreover RB cord-345304-n74m5ucs 37 2 , , , cord-345304-n74m5ucs 37 3 mental mental JJ cord-345304-n74m5ucs 37 4 health health NN cord-345304-n74m5ucs 37 5 burden burden NN cord-345304-n74m5ucs 37 6 and and CC cord-345304-n74m5ucs 37 7 socio socio JJ cord-345304-n74m5ucs 37 8 - - HYPH cord-345304-n74m5ucs 37 9 economic economic JJ cord-345304-n74m5ucs 37 10 issues issue NNS cord-345304-n74m5ucs 37 11 may may MD cord-345304-n74m5ucs 37 12 contribute contribute VB cord-345304-n74m5ucs 37 13 for for IN cord-345304-n74m5ucs 37 14 short short JJ cord-345304-n74m5ucs 37 15 and and CC cord-345304-n74m5ucs 37 16 long long JJ cord-345304-n74m5ucs 37 17 - - HYPH cord-345304-n74m5ucs 37 18 term term NN cord-345304-n74m5ucs 37 19 negative negative JJ cord-345304-n74m5ucs 37 20 outcomes outcome NNS cord-345304-n74m5ucs 37 21 in in IN cord-345304-n74m5ucs 37 22 children child NNS cord-345304-n74m5ucs 37 23 and and CC cord-345304-n74m5ucs 37 24 adolescents adolescent NNS cord-345304-n74m5ucs 37 25 and and CC cord-345304-n74m5ucs 37 26 their -PRON- PRP$ cord-345304-n74m5ucs 37 27 families family NNS cord-345304-n74m5ucs 37 28 . . . cord-345304-n74m5ucs 38 1 Acute acute JJ cord-345304-n74m5ucs 38 2 stress stress NN cord-345304-n74m5ucs 38 3 , , , cord-345304-n74m5ucs 38 4 anxiety anxiety NN cord-345304-n74m5ucs 38 5 , , , cord-345304-n74m5ucs 38 6 mild mild JJ cord-345304-n74m5ucs 38 7 to to IN cord-345304-n74m5ucs 38 8 severe severe JJ cord-345304-n74m5ucs 38 9 depression depression NN cord-345304-n74m5ucs 38 10 , , , cord-345304-n74m5ucs 38 11 post post JJ cord-345304-n74m5ucs 38 12 - - JJ cord-345304-n74m5ucs 38 13 traumatic traumatic JJ cord-345304-n74m5ucs 38 14 stress stress NN cord-345304-n74m5ucs 38 15 disorder disorder NN cord-345304-n74m5ucs 38 16 , , , cord-345304-n74m5ucs 38 17 and and CC cord-345304-n74m5ucs 38 18 emotional emotional JJ cord-345304-n74m5ucs 38 19 exhaustion exhaustion NN cord-345304-n74m5ucs 38 20 may may MD cord-345304-n74m5ucs 38 21 be be VB cord-345304-n74m5ucs 38 22 first first RB cord-345304-n74m5ucs 38 23 diagnosed diagnose VBN cord-345304-n74m5ucs 38 24 during during IN cord-345304-n74m5ucs 38 25 or or CC cord-345304-n74m5ucs 38 26 after after IN cord-345304-n74m5ucs 38 27 COVID-19 covid-19 JJ cord-345304-n74m5ucs 38 28 pandemic pandemic NN cord-345304-n74m5ucs 38 29 . . . cord-345304-n74m5ucs 39 1 Thus thus RB cord-345304-n74m5ucs 39 2 , , , cord-345304-n74m5ucs 39 3 online online JJ cord-345304-n74m5ucs 39 4 mental mental JJ cord-345304-n74m5ucs 39 5 health health NN cord-345304-n74m5ucs 39 6 care care NN cord-345304-n74m5ucs 39 7 delivery delivery NN cord-345304-n74m5ucs 39 8 , , , cord-345304-n74m5ucs 39 9 using use VBG cord-345304-n74m5ucs 39 10 teleconsultation teleconsultation NN cord-345304-n74m5ucs 39 11 or or CC cord-345304-n74m5ucs 39 12 telephone telephone NN cord-345304-n74m5ucs 39 13 support support NN cord-345304-n74m5ucs 39 14 lines line NNS cord-345304-n74m5ucs 39 15 , , , cord-345304-n74m5ucs 39 16 may may MD cord-345304-n74m5ucs 39 17 be be VB cord-345304-n74m5ucs 39 18 required require VBN cord-345304-n74m5ucs 39 19 for for IN cord-345304-n74m5ucs 39 20 pediatric pediatric JJ cord-345304-n74m5ucs 39 21 populations population NNS cord-345304-n74m5ucs 39 22 . . . cord-345304-n74m5ucs 40 1 14 14 CD cord-345304-n74m5ucs 40 2 Identification identification NN cord-345304-n74m5ucs 40 3 of of IN cord-345304-n74m5ucs 40 4 a a DT cord-345304-n74m5ucs 40 5 safe safe JJ cord-345304-n74m5ucs 40 6 and and CC cord-345304-n74m5ucs 40 7 effective effective JJ cord-345304-n74m5ucs 40 8 antiviral antiviral JJ cord-345304-n74m5ucs 40 9 therapy therapy NN cord-345304-n74m5ucs 40 10 , , , cord-345304-n74m5ucs 40 11 that that WDT cord-345304-n74m5ucs 40 12 could could MD cord-345304-n74m5ucs 40 13 improve improve VB cord-345304-n74m5ucs 40 14 disease disease NN cord-345304-n74m5ucs 40 15 outcomes outcome NNS cord-345304-n74m5ucs 40 16 , , , cord-345304-n74m5ucs 40 17 has have VBZ cord-345304-n74m5ucs 40 18 been be VBN cord-345304-n74m5ucs 40 19 object object NN cord-345304-n74m5ucs 40 20 of of IN cord-345304-n74m5ucs 40 21 extensive extensive JJ cord-345304-n74m5ucs 40 22 research research NN cord-345304-n74m5ucs 40 23 worldwide worldwide RB cord-345304-n74m5ucs 40 24 . . . cord-345304-n74m5ucs 41 1 However however RB cord-345304-n74m5ucs 41 2 , , , cord-345304-n74m5ucs 41 3 so so RB cord-345304-n74m5ucs 41 4 far far RB cord-345304-n74m5ucs 41 5 there there EX cord-345304-n74m5ucs 41 6 are be VBP cord-345304-n74m5ucs 41 7 no no DT cord-345304-n74m5ucs 41 8 convincing convincing JJ cord-345304-n74m5ucs 41 9 data datum NNS cord-345304-n74m5ucs 41 10 showing show VBG cord-345304-n74m5ucs 41 11 that that IN cord-345304-n74m5ucs 41 12 any any DT cord-345304-n74m5ucs 41 13 of of IN cord-345304-n74m5ucs 41 14 the the DT cord-345304-n74m5ucs 41 15 several several JJ cord-345304-n74m5ucs 41 16 antivirals antiviral NNS cord-345304-n74m5ucs 41 17 ( ( -LRB- cord-345304-n74m5ucs 41 18 protease protease NN cord-345304-n74m5ucs 41 19 inhibitor inhibitor NN cord-345304-n74m5ucs 41 20 lopinavir lopinavir NNS cord-345304-n74m5ucs 41 21 / / SYM cord-345304-n74m5ucs 41 22 ritonavir ritonavir NNP cord-345304-n74m5ucs 41 23 , , , cord-345304-n74m5ucs 41 24 remdesivir remdesivir NNP cord-345304-n74m5ucs 41 25 or or CC cord-345304-n74m5ucs 41 26 favipiravir favipiravir NNP cord-345304-n74m5ucs 41 27 ) ) -RRB- cord-345304-n74m5ucs 41 28 that that WDT cord-345304-n74m5ucs 41 29 are be VBP cord-345304-n74m5ucs 41 30 being be VBG cord-345304-n74m5ucs 41 31 tested test VBN cord-345304-n74m5ucs 41 32 proved prove VBN cord-345304-n74m5ucs 41 33 to to TO cord-345304-n74m5ucs 41 34 be be VB cord-345304-n74m5ucs 41 35 safe safe JJ cord-345304-n74m5ucs 41 36 and and CC cord-345304-n74m5ucs 41 37 efficacious efficacious JJ cord-345304-n74m5ucs 41 38 against against IN cord-345304-n74m5ucs 41 39 SARS SARS NNP cord-345304-n74m5ucs 41 40 - - HYPH cord-345304-n74m5ucs 41 41 CoV-2 CoV-2 NNP cord-345304-n74m5ucs 41 42 . . . cord-345304-n74m5ucs 42 1 Moreover moreover RB cord-345304-n74m5ucs 42 2 , , , cord-345304-n74m5ucs 42 3 it -PRON- PRP cord-345304-n74m5ucs 42 4 must must MD cord-345304-n74m5ucs 42 5 be be VB cord-345304-n74m5ucs 42 6 acknowledged acknowledge VBN cord-345304-n74m5ucs 42 7 that that IN cord-345304-n74m5ucs 42 8 the the DT cord-345304-n74m5ucs 42 9 majority majority NN cord-345304-n74m5ucs 42 10 of of IN cord-345304-n74m5ucs 42 11 these these DT cord-345304-n74m5ucs 42 12 trials trial NNS cord-345304-n74m5ucs 42 13 have have VBP cord-345304-n74m5ucs 42 14 been be VBN cord-345304-n74m5ucs 42 15 performed perform VBN cord-345304-n74m5ucs 42 16 in in IN cord-345304-n74m5ucs 42 17 adults adult NNS cord-345304-n74m5ucs 42 18 , , , cord-345304-n74m5ucs 42 19 with with IN cord-345304-n74m5ucs 42 20 very very RB cord-345304-n74m5ucs 42 21 limited limited JJ cord-345304-n74m5ucs 42 22 data datum NNS cord-345304-n74m5ucs 42 23 , , , cord-345304-n74m5ucs 42 24 if if IN cord-345304-n74m5ucs 42 25 any any DT cord-345304-n74m5ucs 42 26 , , , cord-345304-n74m5ucs 42 27 for for IN cord-345304-n74m5ucs 42 28 most most JJS cord-345304-n74m5ucs 42 29 of of IN cord-345304-n74m5ucs 42 30 the the DT cord-345304-n74m5ucs 42 31 different different JJ cord-345304-n74m5ucs 42 32 candidate candidate NN cord-345304-n74m5ucs 42 33 antiviral antiviral JJ cord-345304-n74m5ucs 42 34 therapies therapy NNS cord-345304-n74m5ucs 42 35 in in IN cord-345304-n74m5ucs 42 36 children child NNS cord-345304-n74m5ucs 42 37 . . . cord-345304-n74m5ucs 43 1 15 15 CD cord-345304-n74m5ucs 44 1 It -PRON- PRP cord-345304-n74m5ucs 44 2 is be VBZ cord-345304-n74m5ucs 44 3 also also RB cord-345304-n74m5ucs 44 4 of of IN cord-345304-n74m5ucs 44 5 paramount paramount JJ cord-345304-n74m5ucs 44 6 importance importance NN cord-345304-n74m5ucs 44 7 to to TO cord-345304-n74m5ucs 44 8 have have VB cord-345304-n74m5ucs 44 9 in in IN cord-345304-n74m5ucs 44 10 mind mind NN cord-345304-n74m5ucs 44 11 that that IN cord-345304-n74m5ucs 44 12 the the DT cord-345304-n74m5ucs 44 13 overwhelming overwhelming JJ cord-345304-n74m5ucs 44 14 majority majority NN cord-345304-n74m5ucs 44 15 of of IN cord-345304-n74m5ucs 44 16 children child NNS cord-345304-n74m5ucs 44 17 and and CC cord-345304-n74m5ucs 44 18 adolescents adolescent NNS cord-345304-n74m5ucs 44 19 with with IN cord-345304-n74m5ucs 44 20 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 44 21 , , , cord-345304-n74m5ucs 44 22 once once RB cord-345304-n74m5ucs 44 23 infected infect VBN cord-345304-n74m5ucs 44 24 , , , cord-345304-n74m5ucs 44 25 will will MD cord-345304-n74m5ucs 44 26 develop develop VB cord-345304-n74m5ucs 44 27 a a DT cord-345304-n74m5ucs 44 28 mild mild JJ cord-345304-n74m5ucs 44 29 , , , cord-345304-n74m5ucs 44 30 self self NN cord-345304-n74m5ucs 44 31 - - HYPH cord-345304-n74m5ucs 44 32 limited limit VBN cord-345304-n74m5ucs 44 33 form form NN cord-345304-n74m5ucs 44 34 of of IN cord-345304-n74m5ucs 44 35 disease disease NN cord-345304-n74m5ucs 44 36 . . . cord-345304-n74m5ucs 45 1 It -PRON- PRP cord-345304-n74m5ucs 45 2 means mean VBZ cord-345304-n74m5ucs 45 3 that that IN cord-345304-n74m5ucs 45 4 a a DT cord-345304-n74m5ucs 45 5 large large JJ cord-345304-n74m5ucs 45 6 number number NN cord-345304-n74m5ucs 45 7 of of IN cord-345304-n74m5ucs 45 8 patients patient NNS cord-345304-n74m5ucs 45 9 would would MD cord-345304-n74m5ucs 45 10 have have VB cord-345304-n74m5ucs 45 11 to to TO cord-345304-n74m5ucs 45 12 be be VB cord-345304-n74m5ucs 45 13 treated treat VBN cord-345304-n74m5ucs 45 14 in in IN cord-345304-n74m5ucs 45 15 order order NN cord-345304-n74m5ucs 45 16 to to TO cord-345304-n74m5ucs 45 17 demonstrate demonstrate VB cord-345304-n74m5ucs 45 18 the the DT cord-345304-n74m5ucs 45 19 benefits benefit NNS cord-345304-n74m5ucs 45 20 of of IN cord-345304-n74m5ucs 45 21 an an DT cord-345304-n74m5ucs 45 22 antiviral antiviral JJ cord-345304-n74m5ucs 45 23 , , , cord-345304-n74m5ucs 45 24 raising raise VBG cord-345304-n74m5ucs 45 25 concerns concern NNS cord-345304-n74m5ucs 45 26 of of IN cord-345304-n74m5ucs 45 27 the the DT cord-345304-n74m5ucs 45 28 potential potential JJ cord-345304-n74m5ucs 45 29 adverse adverse JJ cord-345304-n74m5ucs 45 30 events event NNS cord-345304-n74m5ucs 45 31 associated associate VBN cord-345304-n74m5ucs 45 32 with with IN cord-345304-n74m5ucs 45 33 this this DT cord-345304-n74m5ucs 45 34 intervention intervention NN cord-345304-n74m5ucs 45 35 . . . cord-345304-n74m5ucs 46 1 This this DT cord-345304-n74m5ucs 46 2 way way NN cord-345304-n74m5ucs 46 3 , , , cord-345304-n74m5ucs 46 4 it -PRON- PRP cord-345304-n74m5ucs 46 5 is be VBZ cord-345304-n74m5ucs 46 6 our -PRON- PRP$ cord-345304-n74m5ucs 46 7 opinion opinion NN cord-345304-n74m5ucs 46 8 that that IN cord-345304-n74m5ucs 46 9 , , , cord-345304-n74m5ucs 46 10 given give VBN cord-345304-n74m5ucs 46 11 the the DT cord-345304-n74m5ucs 46 12 lack lack NN cord-345304-n74m5ucs 46 13 of of IN cord-345304-n74m5ucs 46 14 evidence evidence NN cord-345304-n74m5ucs 46 15 supporting support VBG cord-345304-n74m5ucs 46 16 safety safety NN cord-345304-n74m5ucs 46 17 and and CC cord-345304-n74m5ucs 46 18 efficacy efficacy NN cord-345304-n74m5ucs 46 19 of of IN cord-345304-n74m5ucs 46 20 the the DT cord-345304-n74m5ucs 46 21 current current JJ cord-345304-n74m5ucs 46 22 available available JJ cord-345304-n74m5ucs 46 23 drugs drug NNS cord-345304-n74m5ucs 46 24 for for IN cord-345304-n74m5ucs 46 25 the the DT cord-345304-n74m5ucs 46 26 treatment treatment NN cord-345304-n74m5ucs 46 27 of of IN cord-345304-n74m5ucs 46 28 COVID-19 covid-19 CD cord-345304-n74m5ucs 46 29 in in IN cord-345304-n74m5ucs 46 30 children child NNS cord-345304-n74m5ucs 46 31 and and CC cord-345304-n74m5ucs 46 32 adolescents adolescent NNS cord-345304-n74m5ucs 46 33 , , , cord-345304-n74m5ucs 46 34 only only RB cord-345304-n74m5ucs 46 35 supportive supportive JJ cord-345304-n74m5ucs 46 36 care care NN cord-345304-n74m5ucs 46 37 should should MD cord-345304-n74m5ucs 46 38 be be VB cord-345304-n74m5ucs 46 39 routinely routinely RB cord-345304-n74m5ucs 46 40 recommended recommend VBN cord-345304-n74m5ucs 46 41 for for IN cord-345304-n74m5ucs 46 42 the the DT cord-345304-n74m5ucs 46 43 majority majority NN cord-345304-n74m5ucs 46 44 of of IN cord-345304-n74m5ucs 46 45 cases case NNS cord-345304-n74m5ucs 46 46 . . . cord-345304-n74m5ucs 47 1 In in IN cord-345304-n74m5ucs 47 2 selected select VBN cord-345304-n74m5ucs 47 3 cases case NNS cord-345304-n74m5ucs 47 4 , , , cord-345304-n74m5ucs 47 5 of of IN cord-345304-n74m5ucs 47 6 severe severe JJ cord-345304-n74m5ucs 47 7 disease disease NN cord-345304-n74m5ucs 47 8 presentations presentation NNS cord-345304-n74m5ucs 47 9 or or CC cord-345304-n74m5ucs 47 10 potential potential JJ cord-345304-n74m5ucs 47 11 risk risk NN cord-345304-n74m5ucs 47 12 for for IN cord-345304-n74m5ucs 47 13 disease disease NN cord-345304-n74m5ucs 47 14 progression progression NN cord-345304-n74m5ucs 47 15 due due IN cord-345304-n74m5ucs 47 16 to to IN cord-345304-n74m5ucs 47 17 the the DT cord-345304-n74m5ucs 47 18 presence presence NN cord-345304-n74m5ucs 47 19 of of IN cord-345304-n74m5ucs 47 20 strong strong JJ cord-345304-n74m5ucs 47 21 risk risk NN cord-345304-n74m5ucs 47 22 factors factor NNS cord-345304-n74m5ucs 47 23 , , , cord-345304-n74m5ucs 47 24 the the DT cord-345304-n74m5ucs 47 25 use use NN cord-345304-n74m5ucs 47 26 of of IN cord-345304-n74m5ucs 47 27 antiviral antiviral JJ cord-345304-n74m5ucs 47 28 therapy therapy NN cord-345304-n74m5ucs 47 29 might may MD cord-345304-n74m5ucs 47 30 be be VB cord-345304-n74m5ucs 47 31 considered consider VBN cord-345304-n74m5ucs 47 32 on on IN cord-345304-n74m5ucs 47 33 a a DT cord-345304-n74m5ucs 47 34 case case NN cord-345304-n74m5ucs 47 35 - - HYPH cord-345304-n74m5ucs 47 36 by by IN cord-345304-n74m5ucs 47 37 - - HYPH cord-345304-n74m5ucs 47 38 case case NN cord-345304-n74m5ucs 47 39 individualized individualized JJ cord-345304-n74m5ucs 47 40 decision decision NN cord-345304-n74m5ucs 47 41 , , , cord-345304-n74m5ucs 47 42 assuming assume VBG cord-345304-n74m5ucs 47 43 that that IN cord-345304-n74m5ucs 47 44 the the DT cord-345304-n74m5ucs 47 45 benefits benefit NNS cord-345304-n74m5ucs 47 46 outweigh outweigh VBP cord-345304-n74m5ucs 47 47 risks risk NNS cord-345304-n74m5ucs 47 48 of of IN cord-345304-n74m5ucs 47 49 potential potential JJ cord-345304-n74m5ucs 47 50 adverse adverse JJ cord-345304-n74m5ucs 47 51 events event NNS cord-345304-n74m5ucs 47 52 of of IN cord-345304-n74m5ucs 47 53 the the DT cord-345304-n74m5ucs 47 54 drug drug NN cord-345304-n74m5ucs 47 55 used use VBN cord-345304-n74m5ucs 47 56 . . . cord-345304-n74m5ucs 48 1 It -PRON- PRP cord-345304-n74m5ucs 48 2 is be VBZ cord-345304-n74m5ucs 48 3 recommended recommend VBN cord-345304-n74m5ucs 48 4 that that IN cord-345304-n74m5ucs 48 5 , , , cord-345304-n74m5ucs 48 6 ideally ideally RB cord-345304-n74m5ucs 48 7 , , , cord-345304-n74m5ucs 48 8 these these DT cord-345304-n74m5ucs 48 9 off off IN cord-345304-n74m5ucs 48 10 - - HYPH cord-345304-n74m5ucs 48 11 label label NN cord-345304-n74m5ucs 48 12 antiviral antiviral JJ cord-345304-n74m5ucs 48 13 therapies therapy NNS cord-345304-n74m5ucs 48 14 for for IN cord-345304-n74m5ucs 48 15 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 48 16 should should MD cord-345304-n74m5ucs 48 17 occur occur VB cord-345304-n74m5ucs 48 18 as as IN cord-345304-n74m5ucs 48 19 part part NN cord-345304-n74m5ucs 48 20 of of IN cord-345304-n74m5ucs 48 21 a a DT cord-345304-n74m5ucs 48 22 clinical clinical JJ cord-345304-n74m5ucs 48 23 trial trial NN cord-345304-n74m5ucs 48 24 . . . cord-345304-n74m5ucs 49 1 Post post JJ cord-345304-n74m5ucs 49 2 - - JJ cord-345304-n74m5ucs 49 3 exposure exposure JJ cord-345304-n74m5ucs 49 4 prophylaxis prophylaxis NN cord-345304-n74m5ucs 49 5 is be VBZ cord-345304-n74m5ucs 49 6 another another DT cord-345304-n74m5ucs 49 7 potential potential JJ cord-345304-n74m5ucs 49 8 strategy strategy NN cord-345304-n74m5ucs 49 9 for for IN cord-345304-n74m5ucs 49 10 using use VBG cord-345304-n74m5ucs 49 11 antiviral antiviral JJ cord-345304-n74m5ucs 49 12 therapies therapy NNS cord-345304-n74m5ucs 49 13 . . . cord-345304-n74m5ucs 50 1 In in IN cord-345304-n74m5ucs 50 2 this this DT cord-345304-n74m5ucs 50 3 context context NN cord-345304-n74m5ucs 50 4 , , , cord-345304-n74m5ucs 50 5 a a DT cord-345304-n74m5ucs 50 6 recent recent JJ cord-345304-n74m5ucs 50 7 double double JJ cord-345304-n74m5ucs 50 8 - - HYPH cord-345304-n74m5ucs 50 9 blind blind JJ cord-345304-n74m5ucs 50 10 randomized randomized JJ cord-345304-n74m5ucs 50 11 trial trial NN cord-345304-n74m5ucs 50 12 tested test VBD cord-345304-n74m5ucs 50 13 the the DT cord-345304-n74m5ucs 50 14 use use NN cord-345304-n74m5ucs 50 15 of of IN cord-345304-n74m5ucs 50 16 hydroxychloroquine hydroxychloroquine NN cord-345304-n74m5ucs 50 17 within within IN cord-345304-n74m5ucs 50 18 four four CD cord-345304-n74m5ucs 50 19 days day NNS cord-345304-n74m5ucs 50 20 after after IN cord-345304-n74m5ucs 50 21 the the DT cord-345304-n74m5ucs 50 22 reported report VBN cord-345304-n74m5ucs 50 23 exposure exposure NN cord-345304-n74m5ucs 50 24 . . . cord-345304-n74m5ucs 51 1 However however RB cord-345304-n74m5ucs 51 2 , , , cord-345304-n74m5ucs 51 3 results result NNS cord-345304-n74m5ucs 51 4 did do VBD cord-345304-n74m5ucs 51 5 not not RB cord-345304-n74m5ucs 51 6 show show VB cord-345304-n74m5ucs 51 7 any any DT cord-345304-n74m5ucs 51 8 effect effect NN cord-345304-n74m5ucs 51 9 of of IN cord-345304-n74m5ucs 51 10 this this DT cord-345304-n74m5ucs 51 11 drug drug NN cord-345304-n74m5ucs 51 12 on on IN cord-345304-n74m5ucs 51 13 the the DT cord-345304-n74m5ucs 51 14 prevention prevention NN cord-345304-n74m5ucs 51 15 of of IN cord-345304-n74m5ucs 51 16 illness illness NN cord-345304-n74m5ucs 51 17 compatible compatible JJ cord-345304-n74m5ucs 51 18 with with IN cord-345304-n74m5ucs 51 19 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 51 20 or or CC cord-345304-n74m5ucs 51 21 confirmed confirm VBD cord-345304-n74m5ucs 51 22 SARS SARS NNP cord-345304-n74m5ucs 51 23 - - HYPH cord-345304-n74m5ucs 51 24 CoV-2 CoV-2 NNP cord-345304-n74m5ucs 51 25 infection infection NN cord-345304-n74m5ucs 51 26 when when WRB cord-345304-n74m5ucs 51 27 used use VBN cord-345304-n74m5ucs 51 28 as as IN cord-345304-n74m5ucs 51 29 post post JJ cord-345304-n74m5ucs 51 30 - - JJ cord-345304-n74m5ucs 51 31 exposure exposure JJ cord-345304-n74m5ucs 51 32 prophylaxis prophylaxis NN cord-345304-n74m5ucs 51 33 . . . cord-345304-n74m5ucs 52 1 16 16 CD cord-345304-n74m5ucs 53 1 The the DT cord-345304-n74m5ucs 53 2 most most RBS cord-345304-n74m5ucs 53 3 exciting exciting JJ cord-345304-n74m5ucs 53 4 and and CC cord-345304-n74m5ucs 53 5 fascinating fascinating JJ cord-345304-n74m5ucs 53 6 chapter chapter NN cord-345304-n74m5ucs 53 7 of of IN cord-345304-n74m5ucs 53 8 the the DT cord-345304-n74m5ucs 53 9 battle battle NN cord-345304-n74m5ucs 53 10 against against IN cord-345304-n74m5ucs 53 11 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 53 12 is be VBZ cord-345304-n74m5ucs 53 13 undoubtedly undoubtedly RB cord-345304-n74m5ucs 53 14 the the DT cord-345304-n74m5ucs 53 15 development development NN cord-345304-n74m5ucs 53 16 of of IN cord-345304-n74m5ucs 53 17 a a DT cord-345304-n74m5ucs 53 18 safe safe JJ cord-345304-n74m5ucs 53 19 and and CC cord-345304-n74m5ucs 53 20 effective effective JJ cord-345304-n74m5ucs 53 21 vaccine vaccine NN cord-345304-n74m5ucs 53 22 . . . cord-345304-n74m5ucs 54 1 We -PRON- PRP cord-345304-n74m5ucs 54 2 currently currently RB cord-345304-n74m5ucs 54 3 have have VBP cord-345304-n74m5ucs 54 4 more more JJR cord-345304-n74m5ucs 54 5 than than IN cord-345304-n74m5ucs 54 6 130 130 CD cord-345304-n74m5ucs 54 7 candidate candidate NN cord-345304-n74m5ucs 54 8 vaccines vaccine NNS cord-345304-n74m5ucs 54 9 being be VBG cord-345304-n74m5ucs 54 10 developed develop VBN cord-345304-n74m5ucs 54 11 , , , cord-345304-n74m5ucs 54 12 at at RB cord-345304-n74m5ucs 54 13 least least RBS cord-345304-n74m5ucs 54 14 10 10 CD cord-345304-n74m5ucs 54 15 of of IN cord-345304-n74m5ucs 54 16 them -PRON- PRP cord-345304-n74m5ucs 54 17 already already RB cord-345304-n74m5ucs 54 18 being be VBG cord-345304-n74m5ucs 54 19 tested test VBN cord-345304-n74m5ucs 54 20 in in IN cord-345304-n74m5ucs 54 21 humans human NNS cord-345304-n74m5ucs 54 22 , , , cord-345304-n74m5ucs 54 23 using use VBG cord-345304-n74m5ucs 54 24 different different JJ cord-345304-n74m5ucs 54 25 vaccine vaccine NN cord-345304-n74m5ucs 54 26 platforms platform NNS cord-345304-n74m5ucs 54 27 , , , cord-345304-n74m5ucs 54 28 including include VBG cord-345304-n74m5ucs 54 29 nucleic nucleic JJ cord-345304-n74m5ucs 54 30 acid acid NN cord-345304-n74m5ucs 54 31 - - HYPH cord-345304-n74m5ucs 54 32 based base VBN cord-345304-n74m5ucs 54 33 ( ( -LRB- cord-345304-n74m5ucs 54 34 mRNA mrna NN cord-345304-n74m5ucs 54 35 and and CC cord-345304-n74m5ucs 54 36 DNA DNA NNP cord-345304-n74m5ucs 54 37 ) ) -RRB- cord-345304-n74m5ucs 54 38 , , , cord-345304-n74m5ucs 54 39 vector vector NN cord-345304-n74m5ucs 54 40 - - HYPH cord-345304-n74m5ucs 54 41 based base VBN cord-345304-n74m5ucs 54 42 , , , cord-345304-n74m5ucs 54 43 and and CC cord-345304-n74m5ucs 54 44 inactivated inactivate VBN cord-345304-n74m5ucs 54 45 or or CC cord-345304-n74m5ucs 54 46 recombinant recombinant JJ cord-345304-n74m5ucs 54 47 protein protein NN cord-345304-n74m5ucs 54 48 vaccines vaccine NNS cord-345304-n74m5ucs 54 49 . . . cord-345304-n74m5ucs 55 1 Studies study NNS cord-345304-n74m5ucs 55 2 performed perform VBN cord-345304-n74m5ucs 55 3 with with IN cord-345304-n74m5ucs 55 4 several several JJ cord-345304-n74m5ucs 55 5 vaccine vaccine NN cord-345304-n74m5ucs 55 6 strategies strategy NNS cord-345304-n74m5ucs 55 7 against against IN cord-345304-n74m5ucs 55 8 the the DT cord-345304-n74m5ucs 55 9 other other JJ cord-345304-n74m5ucs 55 10 zoonotic zoonotic JJ cord-345304-n74m5ucs 55 11 coronavirus coronavirus NN cord-345304-n74m5ucs 55 12 , , , cord-345304-n74m5ucs 55 13 SARS SARS NNP cord-345304-n74m5ucs 55 14 - - HYPH cord-345304-n74m5ucs 55 15 CoV CoV NNP cord-345304-n74m5ucs 55 16 and and CC cord-345304-n74m5ucs 55 17 MERS MERS NNP cord-345304-n74m5ucs 55 18 - - HYPH cord-345304-n74m5ucs 55 19 CoV CoV NNP cord-345304-n74m5ucs 55 20 , , , cord-345304-n74m5ucs 55 21 focused focus VBD cord-345304-n74m5ucs 55 22 on on IN cord-345304-n74m5ucs 55 23 the the DT cord-345304-n74m5ucs 55 24 S S NNP cord-345304-n74m5ucs 55 25 protein protein NN cord-345304-n74m5ucs 55 26 target target NN cord-345304-n74m5ucs 55 27 , , , cord-345304-n74m5ucs 55 28 paved pave VBD cord-345304-n74m5ucs 55 29 the the DT cord-345304-n74m5ucs 55 30 way way NN cord-345304-n74m5ucs 55 31 to to TO cord-345304-n74m5ucs 55 32 facilitate facilitate VB cord-345304-n74m5ucs 55 33 a a DT cord-345304-n74m5ucs 55 34 more more RBR cord-345304-n74m5ucs 55 35 rapid rapid JJ cord-345304-n74m5ucs 55 36 development development NN cord-345304-n74m5ucs 55 37 of of IN cord-345304-n74m5ucs 55 38 the the DT cord-345304-n74m5ucs 55 39 current current JJ cord-345304-n74m5ucs 55 40 SARS SARS NNP cord-345304-n74m5ucs 55 41 - - HYPH cord-345304-n74m5ucs 55 42 CoV-2 CoV-2 NNP cord-345304-n74m5ucs 55 43 vaccine vaccine NN cord-345304-n74m5ucs 55 44 . . . cord-345304-n74m5ucs 56 1 17 17 CD cord-345304-n74m5ucs 57 1 Although although IN cord-345304-n74m5ucs 57 2 significant significant JJ cord-345304-n74m5ucs 57 3 progress progress NN cord-345304-n74m5ucs 57 4 has have VBZ cord-345304-n74m5ucs 57 5 been be VBN cord-345304-n74m5ucs 57 6 made make VBN cord-345304-n74m5ucs 57 7 in in IN cord-345304-n74m5ucs 57 8 a a DT cord-345304-n74m5ucs 57 9 very very RB cord-345304-n74m5ucs 57 10 short short JJ cord-345304-n74m5ucs 57 11 period period NN cord-345304-n74m5ucs 57 12 of of IN cord-345304-n74m5ucs 57 13 time time NN cord-345304-n74m5ucs 57 14 , , , cord-345304-n74m5ucs 57 15 we -PRON- PRP cord-345304-n74m5ucs 57 16 still still RB cord-345304-n74m5ucs 57 17 have have VBP cord-345304-n74m5ucs 57 18 several several JJ cord-345304-n74m5ucs 57 19 unanswered unanswered JJ cord-345304-n74m5ucs 57 20 questions question NNS cord-345304-n74m5ucs 57 21 and and CC cord-345304-n74m5ucs 57 22 challenges challenge NNS cord-345304-n74m5ucs 57 23 to to IN cord-345304-n74m5ucs 57 24 the the DT cord-345304-n74m5ucs 57 25 development development NN cord-345304-n74m5ucs 57 26 of of IN cord-345304-n74m5ucs 57 27 a a DT cord-345304-n74m5ucs 57 28 vaccine vaccine NN cord-345304-n74m5ucs 57 29 against against IN cord-345304-n74m5ucs 57 30 SARS SARS NNP cord-345304-n74m5ucs 57 31 - - HYPH cord-345304-n74m5ucs 57 32 CoV-2 CoV-2 NNP cord-345304-n74m5ucs 57 33 , , , cord-345304-n74m5ucs 57 34 including include VBG cord-345304-n74m5ucs 57 35 the the DT cord-345304-n74m5ucs 57 36 theoretical theoretical JJ cord-345304-n74m5ucs 57 37 risk risk NN cord-345304-n74m5ucs 57 38 of of IN cord-345304-n74m5ucs 57 39 Antibody Antibody NNP cord-345304-n74m5ucs 57 40 - - HYPH cord-345304-n74m5ucs 57 41 Dependent Dependent NNP cord-345304-n74m5ucs 57 42 - - HYPH cord-345304-n74m5ucs 57 43 Enhancement Enhancement NNP cord-345304-n74m5ucs 57 44 , , , cord-345304-n74m5ucs 57 45 the the DT cord-345304-n74m5ucs 57 46 lack lack NN cord-345304-n74m5ucs 57 47 of of IN cord-345304-n74m5ucs 57 48 clear clear JJ cord-345304-n74m5ucs 57 49 correlates correlate NNS cord-345304-n74m5ucs 57 50 of of IN cord-345304-n74m5ucs 57 51 protection protection NN cord-345304-n74m5ucs 57 52 , , , cord-345304-n74m5ucs 57 53 the the DT cord-345304-n74m5ucs 57 54 long long JJ cord-345304-n74m5ucs 57 55 - - HYPH cord-345304-n74m5ucs 57 56 term term NN cord-345304-n74m5ucs 57 57 persistence persistence NN cord-345304-n74m5ucs 57 58 of of IN cord-345304-n74m5ucs 57 59 the the DT cord-345304-n74m5ucs 57 60 immune immune JJ cord-345304-n74m5ucs 57 61 responses response NNS cord-345304-n74m5ucs 57 62 induced induce VBN cord-345304-n74m5ucs 57 63 by by IN cord-345304-n74m5ucs 57 64 vaccination vaccination NN cord-345304-n74m5ucs 57 65 , , , cord-345304-n74m5ucs 57 66 the the DT cord-345304-n74m5ucs 57 67 number number NN cord-345304-n74m5ucs 57 68 of of IN cord-345304-n74m5ucs 57 69 vaccine vaccine NN cord-345304-n74m5ucs 57 70 doses dose NNS cord-345304-n74m5ucs 57 71 required require VBN cord-345304-n74m5ucs 57 72 for for IN cord-345304-n74m5ucs 57 73 different different JJ cord-345304-n74m5ucs 57 74 age age NN cord-345304-n74m5ucs 57 75 groups group NNS cord-345304-n74m5ucs 57 76 , , , cord-345304-n74m5ucs 57 77 the the DT cord-345304-n74m5ucs 57 78 probable probable JJ cord-345304-n74m5ucs 57 79 need need NN cord-345304-n74m5ucs 57 80 of of IN cord-345304-n74m5ucs 57 81 adjuvants adjuvant NNS cord-345304-n74m5ucs 57 82 to to TO cord-345304-n74m5ucs 57 83 trigger trigger VB cord-345304-n74m5ucs 57 84 TH1 th1 NN cord-345304-n74m5ucs 57 85 response response NN cord-345304-n74m5ucs 57 86 , , , cord-345304-n74m5ucs 57 87 and and CC cord-345304-n74m5ucs 57 88 high high JJ cord-345304-n74m5ucs 57 89 neutralizing neutralize VBG cord-345304-n74m5ucs 57 90 antibodies antibody NNS cord-345304-n74m5ucs 57 91 to to TO cord-345304-n74m5ucs 57 92 spare spare VB cord-345304-n74m5ucs 57 93 antigen antigen NN cord-345304-n74m5ucs 57 94 dosing dosing NN cord-345304-n74m5ucs 57 95 . . . cord-345304-n74m5ucs 58 1 It -PRON- PRP cord-345304-n74m5ucs 58 2 is be VBZ cord-345304-n74m5ucs 58 3 also also RB cord-345304-n74m5ucs 58 4 difficult difficult JJ cord-345304-n74m5ucs 58 5 to to TO cord-345304-n74m5ucs 58 6 anticipate anticipate VB cord-345304-n74m5ucs 58 7 whether whether IN cord-345304-n74m5ucs 58 8 these these DT cord-345304-n74m5ucs 58 9 vaccines vaccine NNS cord-345304-n74m5ucs 58 10 will will MD cord-345304-n74m5ucs 58 11 provide provide VB cord-345304-n74m5ucs 58 12 protection protection NN cord-345304-n74m5ucs 58 13 against against IN cord-345304-n74m5ucs 58 14 infection infection NN cord-345304-n74m5ucs 58 15 ( ( -LRB- cord-345304-n74m5ucs 58 16 which which WDT cord-345304-n74m5ucs 58 17 would would MD cord-345304-n74m5ucs 58 18 also also RB cord-345304-n74m5ucs 58 19 have have VB cord-345304-n74m5ucs 58 20 the the DT cord-345304-n74m5ucs 58 21 possibility possibility NN cord-345304-n74m5ucs 58 22 to to TO cord-345304-n74m5ucs 58 23 decrease decrease VB cord-345304-n74m5ucs 58 24 transmission transmission NN cord-345304-n74m5ucs 58 25 in in IN cord-345304-n74m5ucs 58 26 the the DT cord-345304-n74m5ucs 58 27 community community NN cord-345304-n74m5ucs 58 28 once once IN cord-345304-n74m5ucs 58 29 high high JJ cord-345304-n74m5ucs 58 30 coverage coverage NN cord-345304-n74m5ucs 58 31 is be VBZ cord-345304-n74m5ucs 58 32 achieved achieve VBN cord-345304-n74m5ucs 58 33 ) ) -RRB- cord-345304-n74m5ucs 58 34 or or CC cord-345304-n74m5ucs 58 35 only only RB cord-345304-n74m5ucs 58 36 prevent prevent VB cord-345304-n74m5ucs 58 37 disease disease NN cord-345304-n74m5ucs 58 38 severity severity NN cord-345304-n74m5ucs 58 39 and/or and/or CC cord-345304-n74m5ucs 58 40 death death NN cord-345304-n74m5ucs 58 41 . . . cord-345304-n74m5ucs 59 1 17 17 CD cord-345304-n74m5ucs 60 1 The the DT cord-345304-n74m5ucs 60 2 role role NN cord-345304-n74m5ucs 60 3 of of IN cord-345304-n74m5ucs 60 4 a a DT cord-345304-n74m5ucs 60 5 recent recent JJ cord-345304-n74m5ucs 60 6 Bacille Bacille NNP cord-345304-n74m5ucs 60 7 - - HYPH cord-345304-n74m5ucs 60 8 Calmette Calmette NNP cord-345304-n74m5ucs 60 9 - - HYPH cord-345304-n74m5ucs 60 10 Guerin Guerin NNP cord-345304-n74m5ucs 60 11 ( ( -LRB- cord-345304-n74m5ucs 60 12 BCG BCG NNP cord-345304-n74m5ucs 60 13 ) ) -RRB- cord-345304-n74m5ucs 60 14 immunization immunization NN cord-345304-n74m5ucs 60 15 in in IN cord-345304-n74m5ucs 60 16 the the DT cord-345304-n74m5ucs 60 17 prevention prevention NN cord-345304-n74m5ucs 60 18 of of IN cord-345304-n74m5ucs 60 19 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 60 20 is be VBZ cord-345304-n74m5ucs 60 21 also also RB cord-345304-n74m5ucs 60 22 being be VBG cord-345304-n74m5ucs 60 23 investigated investigate VBN cord-345304-n74m5ucs 60 24 in in IN cord-345304-n74m5ucs 60 25 clinical clinical JJ cord-345304-n74m5ucs 60 26 trials trial NNS cord-345304-n74m5ucs 60 27 . . . cord-345304-n74m5ucs 61 1 Previous previous JJ cord-345304-n74m5ucs 61 2 studies study NNS cord-345304-n74m5ucs 61 3 have have VBP cord-345304-n74m5ucs 61 4 shown show VBN cord-345304-n74m5ucs 61 5 that that IN cord-345304-n74m5ucs 61 6 BCG BCG NNP cord-345304-n74m5ucs 61 7 immunization immunization NN cord-345304-n74m5ucs 61 8 , , , cord-345304-n74m5ucs 61 9 besides besides IN cord-345304-n74m5ucs 61 10 its -PRON- PRP$ cord-345304-n74m5ucs 61 11 specific specific JJ cord-345304-n74m5ucs 61 12 effect effect NN cord-345304-n74m5ucs 61 13 against against IN cord-345304-n74m5ucs 61 14 severe severe JJ cord-345304-n74m5ucs 61 15 forms form NNS cord-345304-n74m5ucs 61 16 of of IN cord-345304-n74m5ucs 61 17 tuberculosis tuberculosis NN cord-345304-n74m5ucs 61 18 , , , cord-345304-n74m5ucs 61 19 induces induce VBZ cord-345304-n74m5ucs 61 20 a a DT cord-345304-n74m5ucs 61 21 nonspecific nonspecific JJ cord-345304-n74m5ucs 61 22 protective protective JJ cord-345304-n74m5ucs 61 23 immune immune JJ cord-345304-n74m5ucs 61 24 response response NN cord-345304-n74m5ucs 61 25 against against IN cord-345304-n74m5ucs 61 26 other other JJ cord-345304-n74m5ucs 61 27 infections infection NNS cord-345304-n74m5ucs 61 28 . . . cord-345304-n74m5ucs 62 1 17 17 CD cord-345304-n74m5ucs 63 1 In in IN cord-345304-n74m5ucs 63 2 conclusion conclusion NN cord-345304-n74m5ucs 63 3 , , , cord-345304-n74m5ucs 63 4 almost almost RB cord-345304-n74m5ucs 63 5 six six CD cord-345304-n74m5ucs 63 6 months month NNS cord-345304-n74m5ucs 63 7 into into IN cord-345304-n74m5ucs 63 8 the the DT cord-345304-n74m5ucs 63 9 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 63 10 pandemic pandemic NN cord-345304-n74m5ucs 63 11 , , , cord-345304-n74m5ucs 63 12 its -PRON- PRP$ cord-345304-n74m5ucs 63 13 epicenter epicenter NN cord-345304-n74m5ucs 63 14 has have VBZ cord-345304-n74m5ucs 63 15 displaced displace VBN cord-345304-n74m5ucs 63 16 from from IN cord-345304-n74m5ucs 63 17 China China NNP cord-345304-n74m5ucs 63 18 , , , cord-345304-n74m5ucs 63 19 Europe Europe NNP cord-345304-n74m5ucs 63 20 and and CC cord-345304-n74m5ucs 63 21 USA USA NNP cord-345304-n74m5ucs 63 22 to to IN cord-345304-n74m5ucs 63 23 Brazil Brazil NNP cord-345304-n74m5ucs 63 24 , , , cord-345304-n74m5ucs 63 25 exposing expose VBG cord-345304-n74m5ucs 63 26 our -PRON- PRP$ cord-345304-n74m5ucs 63 27 vulnerable vulnerable JJ cord-345304-n74m5ucs 63 28 population population NN cord-345304-n74m5ucs 63 29 to to IN cord-345304-n74m5ucs 63 30 devastating devastating JJ cord-345304-n74m5ucs 63 31 consequences consequence NNS cord-345304-n74m5ucs 63 32 . . . cord-345304-n74m5ucs 64 1 Despite despite IN cord-345304-n74m5ucs 64 2 the the DT cord-345304-n74m5ucs 64 3 fact fact NN cord-345304-n74m5ucs 64 4 that that IN cord-345304-n74m5ucs 64 5 children child NNS cord-345304-n74m5ucs 64 6 and and CC cord-345304-n74m5ucs 64 7 adolescents adolescent NNS cord-345304-n74m5ucs 64 8 appear appear VBP cord-345304-n74m5ucs 64 9 to to TO cord-345304-n74m5ucs 64 10 have have VB cord-345304-n74m5ucs 64 11 lower low JJR cord-345304-n74m5ucs 64 12 prevalence prevalence NN cord-345304-n74m5ucs 64 13 , , , cord-345304-n74m5ucs 64 14 milder mild JJR cord-345304-n74m5ucs 64 15 clinical clinical JJ cord-345304-n74m5ucs 64 16 manifestations manifestation NNS cord-345304-n74m5ucs 64 17 and and CC cord-345304-n74m5ucs 64 18 lower low JJR cord-345304-n74m5ucs 64 19 fatality fatality NN cord-345304-n74m5ucs 64 20 rates rate NNS cord-345304-n74m5ucs 64 21 , , , cord-345304-n74m5ucs 64 22 compared compare VBN cord-345304-n74m5ucs 64 23 to to IN cord-345304-n74m5ucs 64 24 other other JJ cord-345304-n74m5ucs 64 25 age age NN cord-345304-n74m5ucs 64 26 groups group NNS cord-345304-n74m5ucs 64 27 , , , cord-345304-n74m5ucs 64 28 COVID-19 covid-19 JJ cord-345304-n74m5ucs 64 29 global global JJ cord-345304-n74m5ucs 64 30 crisis crisis NN cord-345304-n74m5ucs 64 31 has have VBZ cord-345304-n74m5ucs 64 32 a a DT cord-345304-n74m5ucs 64 33 potentially potentially RB cord-345304-n74m5ucs 64 34 profound profound JJ cord-345304-n74m5ucs 64 35 , , , cord-345304-n74m5ucs 64 36 long long JJ cord-345304-n74m5ucs 64 37 - - HYPH cord-345304-n74m5ucs 64 38 term term NN cord-345304-n74m5ucs 64 39 negative negative JJ cord-345304-n74m5ucs 64 40 impact impact NN cord-345304-n74m5ucs 64 41 on on IN cord-345304-n74m5ucs 64 42 pediatric pediatric JJ cord-345304-n74m5ucs 64 43 populations population NNS cord-345304-n74m5ucs 64 44 . . . cord-345304-n74m5ucs 65 1 The the DT cord-345304-n74m5ucs 65 2 recent recent JJ cord-345304-n74m5ucs 65 3 identification identification NN cord-345304-n74m5ucs 65 4 of of IN cord-345304-n74m5ucs 65 5 rare rare JJ cord-345304-n74m5ucs 65 6 and and CC cord-345304-n74m5ucs 65 7 severe severe JJ cord-345304-n74m5ucs 65 8 inflammatory inflammatory JJ cord-345304-n74m5ucs 65 9 syndrome syndrome NN cord-345304-n74m5ucs 65 10 cases case NNS cord-345304-n74m5ucs 65 11 of of IN cord-345304-n74m5ucs 65 12 COVID-19 covid-19 CD cord-345304-n74m5ucs 65 13 in in IN cord-345304-n74m5ucs 65 14 older old JJR cord-345304-n74m5ucs 65 15 children child NNS cord-345304-n74m5ucs 65 16 and and CC cord-345304-n74m5ucs 65 17 adolescents adolescent NNS cord-345304-n74m5ucs 65 18 highlights highlight VBZ cord-345304-n74m5ucs 65 19 its -PRON- PRP$ cord-345304-n74m5ucs 65 20 unpredictable unpredictable JJ cord-345304-n74m5ucs 65 21 pathogenesis pathogenesis NN cord-345304-n74m5ucs 65 22 spectrum spectrum NN cord-345304-n74m5ucs 65 23 and and CC cord-345304-n74m5ucs 65 24 outcomes outcome NNS cord-345304-n74m5ucs 65 25 . . . cord-345304-n74m5ucs 66 1 Mental mental JJ cord-345304-n74m5ucs 66 2 health health NN cord-345304-n74m5ucs 66 3 burden burden NN cord-345304-n74m5ucs 66 4 , , , cord-345304-n74m5ucs 66 5 social social JJ cord-345304-n74m5ucs 66 6 impact impact NN cord-345304-n74m5ucs 66 7 and and CC cord-345304-n74m5ucs 66 8 financial financial JJ cord-345304-n74m5ucs 66 9 loss loss NN cord-345304-n74m5ucs 66 10 are be VBP cord-345304-n74m5ucs 66 11 important important JJ cord-345304-n74m5ucs 66 12 challenges challenge NNS cord-345304-n74m5ucs 66 13 for for IN cord-345304-n74m5ucs 66 14 children child NNS cord-345304-n74m5ucs 66 15 and and CC cord-345304-n74m5ucs 66 16 adolescents adolescent NNS cord-345304-n74m5ucs 66 17 of of IN cord-345304-n74m5ucs 66 18 this this DT cord-345304-n74m5ucs 66 19 and and CC cord-345304-n74m5ucs 66 20 future future JJ cord-345304-n74m5ucs 66 21 generations generation NNS cord-345304-n74m5ucs 66 22 . . . cord-345304-n74m5ucs 67 1 Further further JJ cord-345304-n74m5ucs 67 2 multicenter multicenter JJ cord-345304-n74m5ucs 67 3 and and CC cord-345304-n74m5ucs 67 4 longitudinal longitudinal JJ cord-345304-n74m5ucs 67 5 pediatrics pediatric NNS cord-345304-n74m5ucs 67 6 studies study NNS cord-345304-n74m5ucs 67 7 with with IN cord-345304-n74m5ucs 67 8 large large JJ cord-345304-n74m5ucs 67 9 populations population NNS cord-345304-n74m5ucs 67 10 will will MD cord-345304-n74m5ucs 67 11 be be VB cord-345304-n74m5ucs 67 12 necessary necessary JJ cord-345304-n74m5ucs 67 13 to to TO cord-345304-n74m5ucs 67 14 clarify clarify VB cord-345304-n74m5ucs 67 15 these these DT cord-345304-n74m5ucs 67 16 findings finding NNS cord-345304-n74m5ucs 67 17 and and CC cord-345304-n74m5ucs 67 18 to to TO cord-345304-n74m5ucs 67 19 evaluate evaluate VB cord-345304-n74m5ucs 67 20 specific specific JJ cord-345304-n74m5ucs 67 21 healthy healthy JJ cord-345304-n74m5ucs 67 22 and and CC cord-345304-n74m5ucs 67 23 preexisting preexisting JJ cord-345304-n74m5ucs 67 24 chronic chronic JJ cord-345304-n74m5ucs 67 25 diseases disease NNS cord-345304-n74m5ucs 67 26 in in IN cord-345304-n74m5ucs 67 27 children child NNS cord-345304-n74m5ucs 67 28 and and CC cord-345304-n74m5ucs 67 29 adolescents adolescent NNS cord-345304-n74m5ucs 67 30 . . . cord-345304-n74m5ucs 68 1 Coronavirus Coronavirus NNP cord-345304-n74m5ucs 68 2 disease disease NN cord-345304-n74m5ucs 68 3 ( ( -LRB- cord-345304-n74m5ucs 68 4 COVID-19 covid-19 VB cord-345304-n74m5ucs 68 5 ) ) -RRB- cord-345304-n74m5ucs 68 6 pandemic pandemic NN cord-345304-n74m5ucs 68 7 . . . cord-345304-n74m5ucs 69 1 Geneva Geneva NNP cord-345304-n74m5ucs 69 2 : : : cord-345304-n74m5ucs 69 3 WHO who WP cord-345304-n74m5ucs 69 4 ; ; : cord-345304-n74m5ucs 70 1 2020 2020 CD cord-345304-n74m5ucs 71 1 The the DT cord-345304-n74m5ucs 71 2 intriguing intriguing JJ cord-345304-n74m5ucs 71 3 features feature NNS cord-345304-n74m5ucs 71 4 of of IN cord-345304-n74m5ucs 71 5 COVID-19 covid-19 CD cord-345304-n74m5ucs 71 6 in in IN cord-345304-n74m5ucs 71 7 children child NNS cord-345304-n74m5ucs 71 8 and and CC cord-345304-n74m5ucs 71 9 its -PRON- PRP$ cord-345304-n74m5ucs 71 10 impact impact NN cord-345304-n74m5ucs 71 11 on on IN cord-345304-n74m5ucs 71 12 the the DT cord-345304-n74m5ucs 71 13 pandemic pandemic NN cord-345304-n74m5ucs 72 1 Why why WRB cord-345304-n74m5ucs 72 2 is be VBZ cord-345304-n74m5ucs 72 3 SARS SARS NNP cord-345304-n74m5ucs 72 4 - - HYPH cord-345304-n74m5ucs 72 5 CoV-2 CoV-2 NNP cord-345304-n74m5ucs 72 6 infection infection NN cord-345304-n74m5ucs 72 7 milder mild JJR cord-345304-n74m5ucs 72 8 among among IN cord-345304-n74m5ucs 72 9 children child NNS cord-345304-n74m5ucs 72 10 ? ? . cord-345304-n74m5ucs 73 1 Hematuria Hematuria NNP cord-345304-n74m5ucs 73 2 associated associate VBN cord-345304-n74m5ucs 73 3 with with IN cord-345304-n74m5ucs 73 4 SARS SARS NNP cord-345304-n74m5ucs 73 5 - - HYPH cord-345304-n74m5ucs 73 6 CoV-2 CoV-2 NNP cord-345304-n74m5ucs 73 7 infection infection NN cord-345304-n74m5ucs 73 8 in in IN cord-345304-n74m5ucs 73 9 a a DT cord-345304-n74m5ucs 73 10 child child NN cord-345304-n74m5ucs 73 11 COVID-19 covid-19 CD cord-345304-n74m5ucs 73 12 transmission transmission NN cord-345304-n74m5ucs 73 13 and and CC cord-345304-n74m5ucs 73 14 children child NNS cord-345304-n74m5ucs 73 15 : : : cord-345304-n74m5ucs 73 16 the the DT cord-345304-n74m5ucs 73 17 child child NN cord-345304-n74m5ucs 73 18 is be VBZ cord-345304-n74m5ucs 73 19 not not RB cord-345304-n74m5ucs 73 20 to to TO cord-345304-n74m5ucs 73 21 blame blame VB cord-345304-n74m5ucs 73 22 Clinical clinical JJ cord-345304-n74m5ucs 73 23 characteristics characteristic NNS cord-345304-n74m5ucs 73 24 of of IN cord-345304-n74m5ucs 73 25 58 58 CD cord-345304-n74m5ucs 73 26 children child NNS cord-345304-n74m5ucs 73 27 with with IN cord-345304-n74m5ucs 73 28 a a DT cord-345304-n74m5ucs 73 29 pediatric pediatric JJ cord-345304-n74m5ucs 73 30 inflammatory inflammatory JJ cord-345304-n74m5ucs 73 31 multisystem multisystem JJ cord-345304-n74m5ucs 73 32 syndrome syndrome NN cord-345304-n74m5ucs 73 33 temporally temporally RB cord-345304-n74m5ucs 73 34 associated associate VBN cord-345304-n74m5ucs 73 35 with with IN cord-345304-n74m5ucs 73 36 SARS SARS NNP cord-345304-n74m5ucs 73 37 - - HYPH cord-345304-n74m5ucs 73 38 CoV-2 CoV-2 NNP cord-345304-n74m5ucs 73 39 Coronavirus Coronavirus NNP cord-345304-n74m5ucs 73 40 Infection infection NN cord-345304-n74m5ucs 73 41 in in IN cord-345304-n74m5ucs 73 42 Pediatric Pediatric NNP cord-345304-n74m5ucs 73 43 Emergency Emergency NNP cord-345304-n74m5ucs 73 44 Departments Departments NNPS cord-345304-n74m5ucs 73 45 ( ( -LRB- cord-345304-n74m5ucs 73 46 CONFIDENCE CONFIDENCE NNP cord-345304-n74m5ucs 73 47 ) ) -RRB- cord-345304-n74m5ucs 73 48 Research Research NNP cord-345304-n74m5ucs 73 49 Group Group NNP cord-345304-n74m5ucs 73 50 . . . cord-345304-n74m5ucs 74 1 Children child NNS cord-345304-n74m5ucs 74 2 with with IN cord-345304-n74m5ucs 74 3 Covid-19 covid-19 NN cord-345304-n74m5ucs 74 4 in in IN cord-345304-n74m5ucs 74 5 pediatric pediatric JJ cord-345304-n74m5ucs 74 6 emergency emergency NN cord-345304-n74m5ucs 74 7 departments department NNS cord-345304-n74m5ucs 74 8 in in IN cord-345304-n74m5ucs 74 9 Italy Italy NNP cord-345304-n74m5ucs 74 10 Response Response NNP cord-345304-n74m5ucs 74 11 Team Team NNP cord-345304-n74m5ucs 74 12 . . . cord-345304-n74m5ucs 75 1 Coronavirus Coronavirus NNP cord-345304-n74m5ucs 75 2 disease disease NN cord-345304-n74m5ucs 75 3 2019 2019 CD cord-345304-n74m5ucs 75 4 in in IN cord-345304-n74m5ucs 75 5 children child NNS cord-345304-n74m5ucs 76 1 -United -United NNP cord-345304-n74m5ucs 76 2 States States NNP cord-345304-n74m5ucs 76 3 Characteristics characteristic NNS cord-345304-n74m5ucs 76 4 and and CC cord-345304-n74m5ucs 76 5 outcomes outcome NNS cord-345304-n74m5ucs 76 6 of of IN cord-345304-n74m5ucs 76 7 children child NNS cord-345304-n74m5ucs 76 8 with with IN cord-345304-n74m5ucs 76 9 coronavirus coronavirus NN cord-345304-n74m5ucs 76 10 disease disease NN cord-345304-n74m5ucs 76 11 2019 2019 CD cord-345304-n74m5ucs 76 12 ( ( -LRB- cord-345304-n74m5ucs 76 13 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 76 14 ) ) -RRB- cord-345304-n74m5ucs 76 15 infection infection NN cord-345304-n74m5ucs 76 16 admitted admit VBD cord-345304-n74m5ucs 76 17 to to IN cord-345304-n74m5ucs 76 18 US US NNP cord-345304-n74m5ucs 76 19 and and CC cord-345304-n74m5ucs 76 20 Canadian canadian JJ cord-345304-n74m5ucs 76 21 pediatric pediatric JJ cord-345304-n74m5ucs 76 22 intensive intensive JJ cord-345304-n74m5ucs 76 23 care care NN cord-345304-n74m5ucs 76 24 units unit NNS cord-345304-n74m5ucs 76 25 Clinical clinical JJ cord-345304-n74m5ucs 76 26 characteristics characteristic NNS cord-345304-n74m5ucs 76 27 and and CC cord-345304-n74m5ucs 76 28 outcomes outcome NNS cord-345304-n74m5ucs 76 29 of of IN cord-345304-n74m5ucs 76 30 hospitalized hospitalize VBN cord-345304-n74m5ucs 76 31 and and CC cord-345304-n74m5ucs 76 32 critically critically RB cord-345304-n74m5ucs 76 33 Ill ill JJ cord-345304-n74m5ucs 76 34 children child NNS cord-345304-n74m5ucs 76 35 and and CC cord-345304-n74m5ucs 76 36 adolescents adolescent NNS cord-345304-n74m5ucs 76 37 with with IN cord-345304-n74m5ucs 76 38 coronavirus coronavirus NN cord-345304-n74m5ucs 76 39 disease disease NN cord-345304-n74m5ucs 76 40 2019 2019 CD cord-345304-n74m5ucs 77 1 ( ( -LRB- cord-345304-n74m5ucs 77 2 COVID-19 covid-19 VB cord-345304-n74m5ucs 77 3 ) ) -RRB- cord-345304-n74m5ucs 77 4 at at IN cord-345304-n74m5ucs 77 5 a a DT cord-345304-n74m5ucs 77 6 tertiary tertiary JJ cord-345304-n74m5ucs 77 7 care care NN cord-345304-n74m5ucs 77 8 medical medical JJ cord-345304-n74m5ucs 77 9 center center NN cord-345304-n74m5ucs 77 10 in in IN cord-345304-n74m5ucs 77 11 New New NNP cord-345304-n74m5ucs 77 12 York York NNP cord-345304-n74m5ucs 77 13 City City NNP cord-345304-n74m5ucs 77 14 Spotlight Spotlight NNP cord-345304-n74m5ucs 77 15 for for IN cord-345304-n74m5ucs 77 16 healthy healthy JJ cord-345304-n74m5ucs 77 17 and and CC cord-345304-n74m5ucs 77 18 preexisting preexisting JJ cord-345304-n74m5ucs 77 19 chronic chronic JJ cord-345304-n74m5ucs 77 20 diseases disease NNS cord-345304-n74m5ucs 77 21 adolescents adolescent NNS cord-345304-n74m5ucs 77 22 during during IN cord-345304-n74m5ucs 77 23 COVID-19 covid-19 CD cord-345304-n74m5ucs 77 24 pandemic pandemic NN cord-345304-n74m5ucs 77 25 Low low JJ cord-345304-n74m5ucs 77 26 incidence incidence NN cord-345304-n74m5ucs 77 27 of of IN cord-345304-n74m5ucs 77 28 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 77 29 in in IN cord-345304-n74m5ucs 77 30 children child NNS cord-345304-n74m5ucs 77 31 and and CC cord-345304-n74m5ucs 77 32 adolescent adolescent JJ cord-345304-n74m5ucs 77 33 post post JJ cord-345304-n74m5ucs 77 34 - - JJ cord-345304-n74m5ucs 77 35 liver liver JJ cord-345304-n74m5ucs 77 36 transplant transplant NN cord-345304-n74m5ucs 77 37 at at IN cord-345304-n74m5ucs 77 38 a a DT cord-345304-n74m5ucs 77 39 Latin latin JJ cord-345304-n74m5ucs 77 40 American american JJ cord-345304-n74m5ucs 77 41 reference reference NN cord-345304-n74m5ucs 77 42 center center NN cord-345304-n74m5ucs 77 43 COVID-19 COVID-19 VBD cord-345304-n74m5ucs 77 44 in in IN cord-345304-n74m5ucs 77 45 children child NNS cord-345304-n74m5ucs 77 46 with with IN cord-345304-n74m5ucs 77 47 cancer cancer NN cord-345304-n74m5ucs 77 48 in in IN cord-345304-n74m5ucs 77 49 New New NNP cord-345304-n74m5ucs 77 50 York York NNP cord-345304-n74m5ucs 77 51 city city NN cord-345304-n74m5ucs 78 1 The the DT cord-345304-n74m5ucs 78 2 psychological psychological JJ cord-345304-n74m5ucs 78 3 impact impact NN cord-345304-n74m5ucs 78 4 of of IN cord-345304-n74m5ucs 78 5 quarantine quarantine NN cord-345304-n74m5ucs 78 6 and and CC cord-345304-n74m5ucs 78 7 how how WRB cord-345304-n74m5ucs 78 8 to to TO cord-345304-n74m5ucs 78 9 reduce reduce VB cord-345304-n74m5ucs 78 10 it -PRON- PRP cord-345304-n74m5ucs 78 11 : : : cord-345304-n74m5ucs 78 12 rapid rapid JJ cord-345304-n74m5ucs 78 13 review review NN cord-345304-n74m5ucs 78 14 of of IN cord-345304-n74m5ucs 78 15 the the DT cord-345304-n74m5ucs 78 16 evidence evidence NN cord-345304-n74m5ucs 78 17 Multicenter multicenter JJ cord-345304-n74m5ucs 78 18 initial initial JJ cord-345304-n74m5ucs 78 19 guidance guidance NN cord-345304-n74m5ucs 78 20 on on IN cord-345304-n74m5ucs 78 21 use use NN cord-345304-n74m5ucs 78 22 of of IN cord-345304-n74m5ucs 78 23 antivirals antiviral NNS cord-345304-n74m5ucs 78 24 for for IN cord-345304-n74m5ucs 78 25 children child NNS cord-345304-n74m5ucs 78 26 with with IN cord-345304-n74m5ucs 78 27 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 78 28 / / SYM cord-345304-n74m5ucs 78 29 SARS SARS NNP cord-345304-n74m5ucs 78 30 - - HYPH cord-345304-n74m5ucs 78 31 CoV-2 CoV-2 NNP cord-345304-n74m5ucs 79 1 A a DT cord-345304-n74m5ucs 79 2 randomized randomized JJ cord-345304-n74m5ucs 79 3 trial trial NN cord-345304-n74m5ucs 79 4 of of IN cord-345304-n74m5ucs 79 5 hydroxychloroquine hydroxychloroquine NN cord-345304-n74m5ucs 79 6 as as IN cord-345304-n74m5ucs 79 7 postexposure postexposure NN cord-345304-n74m5ucs 79 8 prophylaxis prophylaxis NN cord-345304-n74m5ucs 79 9 for for IN cord-345304-n74m5ucs 79 10 COVID-19 COVID-19 NNP cord-345304-n74m5ucs 79 11 The the DT cord-345304-n74m5ucs 79 12 challenges challenge NNS cord-345304-n74m5ucs 79 13 of of IN cord-345304-n74m5ucs 79 14 vaccine vaccine NN cord-345304-n74m5ucs 79 15 development development NN cord-345304-n74m5ucs 79 16 against against IN cord-345304-n74m5ucs 79 17 a a DT cord-345304-n74m5ucs 79 18 new new JJ cord-345304-n74m5ucs 79 19 virus virus NN cord-345304-n74m5ucs 79 20 during during IN cord-345304-n74m5ucs 79 21 a a DT cord-345304-n74m5ucs 79 22 pandemic pandemic NN cord-345304-n74m5ucs 80 1 The the DT cord-345304-n74m5ucs 80 2 authors author NNS cord-345304-n74m5ucs 80 3 declare declare VBP cord-345304-n74m5ucs 80 4 no no DT cord-345304-n74m5ucs 80 5 conflict conflict NN cord-345304-n74m5ucs 80 6 of of IN cord-345304-n74m5ucs 80 7 interests interest NNS cord-345304-n74m5ucs 80 8 . . . cord-345304-n74m5ucs 81 1 This this DT cord-345304-n74m5ucs 81 2 study study NN cord-345304-n74m5ucs 81 3 was be VBD cord-345304-n74m5ucs 81 4 supported support VBN cord-345304-n74m5ucs 81 5 by by IN cord-345304-n74m5ucs 81 6 grants grant NNS cord-345304-n74m5ucs 81 7 from from IN cord-345304-n74m5ucs 81 8 Conselho Conselho NNP cord-345304-n74m5ucs 81 9 Nacional Nacional NNP cord-345304-n74m5ucs 81 10 de de NNP cord-345304-n74m5ucs 81 11 Desenvolvimento Desenvolvimento NNP cord-345304-n74m5ucs 81 12 Científico Científico NNP cord-345304-n74m5ucs 81 13 e e NNP cord-345304-n74m5ucs 81 14 Tecnológico Tecnológico NNP cord-345304-n74m5ucs 81 15 ( ( -LRB- cord-345304-n74m5ucs 81 16 CNPq CNPq NNP cord-345304-n74m5ucs 81 17 303422/2015 303422/2015 CD cord-345304-n74m5ucs 81 18 - - SYM cord-345304-n74m5ucs 81 19 7 7 CD cord-345304-n74m5ucs 81 20 to to IN cord-345304-n74m5ucs 81 21 CAS CAS NNP cord-345304-n74m5ucs 81 22 ) ) -RRB- cord-345304-n74m5ucs 81 23 , , . cord-345304-n74m5ucs 82 1 Fundação Fundação NNP cord-345304-n74m5ucs 82 2 de de NNP cord-345304-n74m5ucs 82 3 Amparo Amparo NNP cord-345304-n74m5ucs 82 4 à à FW cord-345304-n74m5ucs 82 5 Pesquisa Pesquisa NNP cord-345304-n74m5ucs 82 6 do do VBP cord-345304-n74m5ucs 82 7 Estado Estado NNP cord-345304-n74m5ucs 82 8 de de FW cord-345304-n74m5ucs 82 9 São São NNP cord-345304-n74m5ucs 82 10 Paulo Paulo NNP cord-345304-n74m5ucs 82 11 ( ( -LRB- cord-345304-n74m5ucs 82 12 FAPESP FAPESP NNP cord-345304-n74m5ucs 82 13 2015/03756 2015/03756 CD cord-345304-n74m5ucs 82 14 - - SYM cord-345304-n74m5ucs 82 15 4 4 CD cord-345304-n74m5ucs 82 16 to to IN cord-345304-n74m5ucs 82 17 CAS CAS NNP cord-345304-n74m5ucs 82 18 ) ) -RRB- cord-345304-n74m5ucs 82 19 , , , cord-345304-n74m5ucs 82 20 and and CC cord-345304-n74m5ucs 83 1 by by IN cord-345304-n74m5ucs 83 2 Núcleo Núcleo NNP cord-345304-n74m5ucs 83 3 de de NNP cord-345304-n74m5ucs 83 4 Apoio Apoio NNP cord-345304-n74m5ucs 83 5 à à IN cord-345304-n74m5ucs 83 6 Pesquisa Pesquisa NNP cord-345304-n74m5ucs 83 7 " " `` cord-345304-n74m5ucs 83 8 Saúde Saúde NNP cord-345304-n74m5ucs 83 9 da da NNP cord-345304-n74m5ucs 83 10 Criança Criança NNP cord-345304-n74m5ucs 83 11 e e NN cord-345304-n74m5ucs 83 12 do do NN cord-345304-n74m5ucs 84 1 Adolescente Adolescente NNP cord-345304-n74m5ucs 84 2 " " `` cord-345304-n74m5ucs 84 3 da da NNP cord-345304-n74m5ucs 84 4 USP USP NNP cord-345304-n74m5ucs 84 5 ( ( -LRB- cord-345304-n74m5ucs 84 6 NAP nap NN cord-345304-n74m5ucs 84 7 - - HYPH cord-345304-n74m5ucs 84 8 CriAd criad NN cord-345304-n74m5ucs 84 9 ) ) -RRB- cord-345304-n74m5ucs 84 10 to to IN cord-345304-n74m5ucs 84 11 CAS CAS NNP cord-345304-n74m5ucs 84 12 . . .