id	sid	tid	token	lemma	pos
cord-344382-vge4ho2v	1	1	key	key	NN
cord-344382-vge4ho2v	1	2	:	:	:
cord-344382-vge4ho2v	2	1	cord-344382-vge4ho2v	cord-344382-vge4ho2v	NNP
cord-344382-vge4ho2v	2	2	authors	author	NNS
cord-344382-vge4ho2v	2	3	:	:	:
cord-344382-vge4ho2v	2	4	De	De	NNP
cord-344382-vge4ho2v	2	5	Flora	Flora	NNP
cord-344382-vge4ho2v	2	6	,	,	,
cord-344382-vge4ho2v	2	7	Silvio	Silvio	NNP
cord-344382-vge4ho2v	2	8	;	;	:
cord-344382-vge4ho2v	2	9	Balansky	Balansky	NNP
cord-344382-vge4ho2v	2	10	,	,	,
cord-344382-vge4ho2v	2	11	Roumen	Roumen	NNP
cord-344382-vge4ho2v	2	12	;	;	:
cord-344382-vge4ho2v	2	13	La	La	NNP
cord-344382-vge4ho2v	2	14	Maestra	Maestra	NNP
cord-344382-vge4ho2v	2	15	,	,	,
cord-344382-vge4ho2v	2	16	Sebastiano	Sebastiano	NNP
cord-344382-vge4ho2v	2	17	title	title	NN
cord-344382-vge4ho2v	2	18	:	:	:
cord-344382-vge4ho2v	2	19	Rationale	rationale	NN
cord-344382-vge4ho2v	2	20	for	for	IN
cord-344382-vge4ho2v	2	21	the	the	DT
cord-344382-vge4ho2v	2	22	use	use	NN
cord-344382-vge4ho2v	2	23	of	of	IN
cord-344382-vge4ho2v	2	24	N‐acetylcysteine	N‐acetylcysteine	NNP
cord-344382-vge4ho2v	2	25	in	in	IN
cord-344382-vge4ho2v	2	26	both	both	DT
cord-344382-vge4ho2v	2	27	prevention	prevention	NN
cord-344382-vge4ho2v	2	28	and	and	CC
cord-344382-vge4ho2v	2	29	adjuvant	adjuvant	NN
cord-344382-vge4ho2v	2	30	therapy	therapy	NN
cord-344382-vge4ho2v	2	31	of	of	IN
cord-344382-vge4ho2v	2	32	COVID‐19	COVID‐19	NNP
cord-344382-vge4ho2v	2	33	date	date	NN
cord-344382-vge4ho2v	2	34	:	:	:
cord-344382-vge4ho2v	2	35	2020	2020	CD
cord-344382-vge4ho2v	2	36	-	-	HYPH
cord-344382-vge4ho2v	2	37	08	08	CD
cord-344382-vge4ho2v	2	38	-	-	HYPH
cord-344382-vge4ho2v	2	39	11	11	CD
cord-344382-vge4ho2v	2	40	journal	journal	NN
cord-344382-vge4ho2v	2	41	:	:	:
cord-344382-vge4ho2v	2	42	FASEB	FASEB	NNP
cord-344382-vge4ho2v	2	43	J	J	NNP
cord-344382-vge4ho2v	2	44	DOI	DOI	NNP
cord-344382-vge4ho2v	2	45	:	:	:
cord-344382-vge4ho2v	3	1	10.1096	10.1096	CD
cord-344382-vge4ho2v	3	2	/	/	SYM
cord-344382-vge4ho2v	3	3	fj.202001807	fj.202001807	NNP
cord-344382-vge4ho2v	3	4	sha	sha	NNP
cord-344382-vge4ho2v	3	5	:	:	:
cord-344382-vge4ho2v	4	1	bf0b014adbee2f36ff1c2797d0143d705de042ac	bf0b014adbee2f36ff1c2797d0143d705de042ac	NNP
cord-344382-vge4ho2v	4	2	doc_id	doc_id	CD
cord-344382-vge4ho2v	4	3	:	:	:
cord-344382-vge4ho2v	4	4	344382	344382	CD
cord-344382-vge4ho2v	4	5	cord_uid	cord_uid	NNS
cord-344382-vge4ho2v	4	6	:	:	:
cord-344382-vge4ho2v	4	7	vge4ho2v	vge4ho2v	ADD
cord-344382-vge4ho2v	5	1	COVID‐19	COVID‐19	NNP
cord-344382-vge4ho2v	5	2	may	may	MD
cord-344382-vge4ho2v	5	3	cause	cause	VB
cord-344382-vge4ho2v	5	4	pneumonia	pneumonia	NN
cord-344382-vge4ho2v	5	5	,	,	,
cord-344382-vge4ho2v	5	6	acute	acute	JJ
cord-344382-vge4ho2v	5	7	respiratory	respiratory	JJ
cord-344382-vge4ho2v	5	8	distress	distress	NN
cord-344382-vge4ho2v	5	9	syndrome	syndrome	NN
cord-344382-vge4ho2v	5	10	,	,	,
cord-344382-vge4ho2v	5	11	cardiovascular	cardiovascular	JJ
cord-344382-vge4ho2v	5	12	alterations	alteration	NNS
cord-344382-vge4ho2v	5	13	,	,	,
cord-344382-vge4ho2v	5	14	and	and	CC
cord-344382-vge4ho2v	5	15	multiple	multiple	JJ
cord-344382-vge4ho2v	5	16	organ	organ	NN
cord-344382-vge4ho2v	5	17	failure	failure	NN
cord-344382-vge4ho2v	5	18	,	,	,
cord-344382-vge4ho2v	5	19	which	which	WDT
cord-344382-vge4ho2v	5	20	have	have	VBP
cord-344382-vge4ho2v	5	21	been	be	VBN
cord-344382-vge4ho2v	5	22	ascribed	ascribe	VBN
cord-344382-vge4ho2v	5	23	to	to	IN
cord-344382-vge4ho2v	5	24	a	a	DT
cord-344382-vge4ho2v	5	25	cytokine	cytokine	NN
cord-344382-vge4ho2v	5	26	storm	storm	NN
cord-344382-vge4ho2v	5	27	,	,	,
cord-344382-vge4ho2v	5	28	a	a	DT
cord-344382-vge4ho2v	5	29	systemic	systemic	JJ
cord-344382-vge4ho2v	5	30	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	5	31	response	response	NN
cord-344382-vge4ho2v	5	32	,	,	,
cord-344382-vge4ho2v	5	33	and	and	CC
cord-344382-vge4ho2v	5	34	an	an	DT
cord-344382-vge4ho2v	5	35	attack	attack	NN
cord-344382-vge4ho2v	5	36	by	by	IN
cord-344382-vge4ho2v	5	37	the	the	DT
cord-344382-vge4ho2v	5	38	immune	immune	JJ
cord-344382-vge4ho2v	5	39	system	system	NN
cord-344382-vge4ho2v	5	40	.	.	.
cord-344382-vge4ho2v	6	1	Moreover	moreover	RB
cord-344382-vge4ho2v	6	2	,	,	,
cord-344382-vge4ho2v	6	3	an	an	DT
cord-344382-vge4ho2v	6	4	oxidative	oxidative	JJ
cord-344382-vge4ho2v	6	5	stress	stress	NN
cord-344382-vge4ho2v	6	6	imbalance	imbalance	NN
cord-344382-vge4ho2v	6	7	has	have	VBZ
cord-344382-vge4ho2v	6	8	been	be	VBN
cord-344382-vge4ho2v	6	9	demonstrated	demonstrate	VBN
cord-344382-vge4ho2v	6	10	to	to	TO
cord-344382-vge4ho2v	6	11	occur	occur	VB
cord-344382-vge4ho2v	6	12	in	in	IN
cord-344382-vge4ho2v	6	13	COVID‐19	COVID‐19	NNP
cord-344382-vge4ho2v	6	14	patients	patient	NNS
cord-344382-vge4ho2v	6	15	.	.	.
cord-344382-vge4ho2v	7	1	N‐	N‐	NNP
cord-344382-vge4ho2v	7	2	Acetyl‐L‐cysteine	Acetyl‐L‐cysteine	NNP
cord-344382-vge4ho2v	7	3	(	(	-LRB-
cord-344382-vge4ho2v	7	4	NAC	NAC	NNP
cord-344382-vge4ho2v	7	5	)	)	-RRB-
cord-344382-vge4ho2v	7	6	is	be	VBZ
cord-344382-vge4ho2v	7	7	a	a	DT
cord-344382-vge4ho2v	7	8	precursor	precursor	NN
cord-344382-vge4ho2v	7	9	of	of	IN
cord-344382-vge4ho2v	7	10	reduced	reduce	VBN
cord-344382-vge4ho2v	7	11	glutathione	glutathione	NN
cord-344382-vge4ho2v	7	12	(	(	-LRB-
cord-344382-vge4ho2v	7	13	GSH	GSH	NNP
cord-344382-vge4ho2v	7	14	)	)	-RRB-
cord-344382-vge4ho2v	7	15	.	.	.
cord-344382-vge4ho2v	8	1	Due	due	IN
cord-344382-vge4ho2v	8	2	to	to	IN
cord-344382-vge4ho2v	8	3	its	-PRON-	PRP$
cord-344382-vge4ho2v	8	4	tolerability	tolerability	NN
cord-344382-vge4ho2v	8	5	,	,	,
cord-344382-vge4ho2v	8	6	this	this	DT
cord-344382-vge4ho2v	8	7	pleiotropic	pleiotropic	JJ
cord-344382-vge4ho2v	8	8	drug	drug	NN
cord-344382-vge4ho2v	8	9	has	have	VBZ
cord-344382-vge4ho2v	8	10	been	be	VBN
cord-344382-vge4ho2v	8	11	proposed	propose	VBN
cord-344382-vge4ho2v	8	12	not	not	RB
cord-344382-vge4ho2v	8	13	only	only	RB
cord-344382-vge4ho2v	8	14	as	as	IN
cord-344382-vge4ho2v	8	15	a	a	DT
cord-344382-vge4ho2v	8	16	mucolytic	mucolytic	JJ
cord-344382-vge4ho2v	8	17	agent	agent	NN
cord-344382-vge4ho2v	8	18	,	,	,
cord-344382-vge4ho2v	8	19	but	but	CC
cord-344382-vge4ho2v	8	20	also	also	RB
cord-344382-vge4ho2v	8	21	as	as	IN
cord-344382-vge4ho2v	8	22	a	a	DT
cord-344382-vge4ho2v	8	23	preventive	preventive	JJ
cord-344382-vge4ho2v	8	24	/	/	SYM
cord-344382-vge4ho2v	8	25	therapeutic	therapeutic	JJ
cord-344382-vge4ho2v	8	26	agent	agent	NN
cord-344382-vge4ho2v	8	27	in	in	IN
cord-344382-vge4ho2v	8	28	a	a	DT
cord-344382-vge4ho2v	8	29	variety	variety	NN
cord-344382-vge4ho2v	8	30	of	of	IN
cord-344382-vge4ho2v	8	31	disorders	disorder	NNS
cord-344382-vge4ho2v	8	32	involving	involve	VBG
cord-344382-vge4ho2v	8	33	GSH	GSH	NNP
cord-344382-vge4ho2v	8	34	depletion	depletion	NN
cord-344382-vge4ho2v	8	35	and	and	CC
cord-344382-vge4ho2v	8	36	oxidative	oxidative	JJ
cord-344382-vge4ho2v	8	37	stress	stress	NN
cord-344382-vge4ho2v	8	38	.	.	.
cord-344382-vge4ho2v	9	1	At	at	IN
cord-344382-vge4ho2v	9	2	very	very	RB
cord-344382-vge4ho2v	9	3	high	high	JJ
cord-344382-vge4ho2v	9	4	doses	dose	NNS
cord-344382-vge4ho2v	9	5	,	,	,
cord-344382-vge4ho2v	9	6	NAC	NAC	NNP
cord-344382-vge4ho2v	9	7	is	be	VBZ
cord-344382-vge4ho2v	9	8	also	also	RB
cord-344382-vge4ho2v	9	9	used	use	VBN
cord-344382-vge4ho2v	9	10	as	as	IN
cord-344382-vge4ho2v	9	11	an	an	DT
cord-344382-vge4ho2v	9	12	antidote	antidote	NN
cord-344382-vge4ho2v	9	13	against	against	IN
cord-344382-vge4ho2v	9	14	paracetamol	paracetamol	JJ
cord-344382-vge4ho2v	9	15	intoxication	intoxication	NN
cord-344382-vge4ho2v	9	16	.	.	.
cord-344382-vge4ho2v	10	1	Thiols	Thiols	NNP
cord-344382-vge4ho2v	10	2	block	block	VBP
cord-344382-vge4ho2v	10	3	the	the	DT
cord-344382-vge4ho2v	10	4	angiotensin‐converting	angiotensin‐converting	NNP
cord-344382-vge4ho2v	10	5	enzyme	enzyme	NN
cord-344382-vge4ho2v	10	6	2	2	CD
cord-344382-vge4ho2v	10	7	thereby	thereby	RB
cord-344382-vge4ho2v	10	8	hampering	hamper	VBG
cord-344382-vge4ho2v	10	9	penetration	penetration	NN
cord-344382-vge4ho2v	10	10	of	of	IN
cord-344382-vge4ho2v	10	11	SARS‐CoV‐2	sars‐cov‐2	NN
cord-344382-vge4ho2v	10	12	into	into	IN
cord-344382-vge4ho2v	10	13	cells	cell	NNS
cord-344382-vge4ho2v	10	14	.	.	.
cord-344382-vge4ho2v	11	1	Based	base	VBN
cord-344382-vge4ho2v	11	2	on	on	IN
cord-344382-vge4ho2v	11	3	a	a	DT
cord-344382-vge4ho2v	11	4	broad	broad	JJ
cord-344382-vge4ho2v	11	5	range	range	NN
cord-344382-vge4ho2v	11	6	of	of	IN
cord-344382-vge4ho2v	11	7	antioxidant	antioxidant	JJ
cord-344382-vge4ho2v	11	8	and	and	CC
cord-344382-vge4ho2v	11	9	anti‐inflammatory	anti‐inflammatory	JJ
cord-344382-vge4ho2v	11	10	mechanisms	mechanism	NNS
cord-344382-vge4ho2v	11	11	,	,	,
cord-344382-vge4ho2v	11	12	which	which	WDT
cord-344382-vge4ho2v	11	13	are	be	VBP
cord-344382-vge4ho2v	11	14	herein	herein	RB
cord-344382-vge4ho2v	11	15	reviewed	review	VBN
cord-344382-vge4ho2v	11	16	,	,	,
cord-344382-vge4ho2v	11	17	the	the	DT
cord-344382-vge4ho2v	11	18	oral	oral	JJ
cord-344382-vge4ho2v	11	19	administration	administration	NN
cord-344382-vge4ho2v	11	20	of	of	IN
cord-344382-vge4ho2v	11	21	NAC	NAC	NNP
cord-344382-vge4ho2v	11	22	is	be	VBZ
cord-344382-vge4ho2v	11	23	likely	likely	JJ
cord-344382-vge4ho2v	11	24	to	to	TO
cord-344382-vge4ho2v	11	25	attenuate	attenuate	VB
cord-344382-vge4ho2v	11	26	the	the	DT
cord-344382-vge4ho2v	11	27	risk	risk	NN
cord-344382-vge4ho2v	11	28	of	of	IN
cord-344382-vge4ho2v	11	29	developing	develop	VBG
cord-344382-vge4ho2v	11	30	COVID‐19	covid‐19	NN
cord-344382-vge4ho2v	11	31	,	,	,
cord-344382-vge4ho2v	11	32	as	as	IN
cord-344382-vge4ho2v	11	33	it	-PRON-	PRP
cord-344382-vge4ho2v	11	34	was	be	VBD
cord-344382-vge4ho2v	11	35	previously	previously	RB
cord-344382-vge4ho2v	11	36	demonstrated	demonstrate	VBN
cord-344382-vge4ho2v	11	37	for	for	IN
cord-344382-vge4ho2v	11	38	influenza	influenza	NN
cord-344382-vge4ho2v	11	39	and	and	CC
cord-344382-vge4ho2v	11	40	influenza‐like	influenza‐like	JJ
cord-344382-vge4ho2v	11	41	illnesses	illness	NNS
cord-344382-vge4ho2v	11	42	.	.	.
cord-344382-vge4ho2v	12	1	Moreover	moreover	RB
cord-344382-vge4ho2v	12	2	,	,	,
cord-344382-vge4ho2v	12	3	high‐dose	high‐dose	PRP$
cord-344382-vge4ho2v	12	4	intravenous	intravenous	JJ
cord-344382-vge4ho2v	12	5	NAC	NAC	NNP
cord-344382-vge4ho2v	12	6	may	may	MD
cord-344382-vge4ho2v	12	7	be	be	VB
cord-344382-vge4ho2v	12	8	expected	expect	VBN
cord-344382-vge4ho2v	12	9	to	to	TO
cord-344382-vge4ho2v	12	10	play	play	VB
cord-344382-vge4ho2v	12	11	an	an	DT
cord-344382-vge4ho2v	12	12	adjuvant	adjuvant	JJ
cord-344382-vge4ho2v	12	13	role	role	NN
cord-344382-vge4ho2v	12	14	in	in	IN
cord-344382-vge4ho2v	12	15	the	the	DT
cord-344382-vge4ho2v	12	16	treatment	treatment	NN
cord-344382-vge4ho2v	12	17	of	of	IN
cord-344382-vge4ho2v	12	18	severe	severe	JJ
cord-344382-vge4ho2v	12	19	COVID‐19	covid‐19	NN
cord-344382-vge4ho2v	12	20	cases	case	NNS
cord-344382-vge4ho2v	12	21	and	and	CC
cord-344382-vge4ho2v	12	22	in	in	IN
cord-344382-vge4ho2v	12	23	the	the	DT
cord-344382-vge4ho2v	12	24	control	control	NN
cord-344382-vge4ho2v	12	25	of	of	IN
cord-344382-vge4ho2v	12	26	its	-PRON-	PRP$
cord-344382-vge4ho2v	12	27	lethal	lethal	JJ
cord-344382-vge4ho2v	12	28	complications	complication	NNS
cord-344382-vge4ho2v	12	29	,	,	,
cord-344382-vge4ho2v	12	30	also	also	RB
cord-344382-vge4ho2v	12	31	including	include	VBG
cord-344382-vge4ho2v	12	32	pulmonary	pulmonary	JJ
cord-344382-vge4ho2v	12	33	and	and	CC
cord-344382-vge4ho2v	12	34	cardiovascular	cardiovascular	JJ
cord-344382-vge4ho2v	12	35	adverse	adverse	JJ
cord-344382-vge4ho2v	12	36	events	event	NNS
cord-344382-vge4ho2v	12	37	.	.	.
cord-344382-vge4ho2v	13	1	Approximately	approximately	RB
cord-344382-vge4ho2v	13	2	15	15	CD
cord-344382-vge4ho2v	13	3	%	%	NN
cord-344382-vge4ho2v	13	4	of	of	IN
cord-344382-vge4ho2v	13	5	coronavirus	coronavirus	NN
cord-344382-vge4ho2v	13	6	disease-2019	disease-2019	NNP
cord-344382-vge4ho2v	13	7	(	(	-LRB-
cord-344382-vge4ho2v	13	8	COVID-	covid-	NN
cord-344382-vge4ho2v	13	9	19	19	CD
cord-344382-vge4ho2v	13	10	)	)	-RRB-
cord-344382-vge4ho2v	13	11	patients	patient	NNS
cord-344382-vge4ho2v	13	12	suffer	suffer	VBP
cord-344382-vge4ho2v	13	13	from	from	IN
cord-344382-vge4ho2v	13	14	impairment	impairment	NN
cord-344382-vge4ho2v	13	15	of	of	IN
cord-344382-vge4ho2v	13	16	gas	gas	NN
cord-344382-vge4ho2v	13	17	exchange	exchange	NN
cord-344382-vge4ho2v	13	18	and	and	CC
cord-344382-vge4ho2v	13	19	pneumonia	pneumonia	NN
cord-344382-vge4ho2v	13	20	,	,	,
cord-344382-vge4ho2v	13	21	and	and	CC
cord-344382-vge4ho2v	13	22	5	5	CD
cord-344382-vge4ho2v	13	23	%	%	NN
cord-344382-vge4ho2v	13	24	undergo	undergo	VBP
cord-344382-vge4ho2v	13	25	acute	acute	JJ
cord-344382-vge4ho2v	13	26	respiratory	respiratory	JJ
cord-344382-vge4ho2v	13	27	distress	distress	NN
cord-344382-vge4ho2v	13	28	syndrome	syndrome	NN
cord-344382-vge4ho2v	13	29	(	(	-LRB-
cord-344382-vge4ho2v	13	30	ARDS	ARDS	NNP
cord-344382-vge4ho2v	13	31	)	)	-RRB-
cord-344382-vge4ho2v	13	32	,	,	,
cord-344382-vge4ho2v	13	33	septic	septic	JJ
cord-344382-vge4ho2v	13	34	shock	shock	NN
cord-344382-vge4ho2v	13	35	and/or	and/or	CC
cord-344382-vge4ho2v	13	36	multiple	multiple	JJ
cord-344382-vge4ho2v	13	37	organ	organ	NN
cord-344382-vge4ho2v	13	38	failure	failure	NN
cord-344382-vge4ho2v	13	39	that	that	WDT
cord-344382-vge4ho2v	13	40	require	require	VBP
cord-344382-vge4ho2v	13	41	hospitalization	hospitalization	NN
cord-344382-vge4ho2v	13	42	in	in	IN
cord-344382-vge4ho2v	13	43	intensive	intensive	JJ
cord-344382-vge4ho2v	13	44	care	care	NN
cord-344382-vge4ho2v	13	45	units	unit	NNS
cord-344382-vge4ho2v	13	46	(	(	-LRB-
cord-344382-vge4ho2v	13	47	ICU	ICU	NNP
cord-344382-vge4ho2v	13	48	)	)	-RRB-
cord-344382-vge4ho2v	13	49	.	.	.
cord-344382-vge4ho2v	14	1	1	1	CD
cord-344382-vge4ho2v	14	2	ARDS	ARDS	NNP
cord-344382-vge4ho2v	14	3	,	,	,
cord-344382-vge4ho2v	14	4	the	the	DT
cord-344382-vge4ho2v	14	5	leading	lead	VBG
cord-344382-vge4ho2v	14	6	cause	cause	NN
cord-344382-vge4ho2v	14	7	of	of	IN
cord-344382-vge4ho2v	14	8	death	death	NN
cord-344382-vge4ho2v	14	9	in	in	IN
cord-344382-vge4ho2v	14	10	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	14	11	patients	patient	NNS
cord-344382-vge4ho2v	14	12	,	,	,
cord-344382-vge4ho2v	14	13	involves	involve	VBZ
cord-344382-vge4ho2v	14	14	a	a	DT
cord-344382-vge4ho2v	14	15	cytokine	cytokine	NN
cord-344382-vge4ho2v	14	16	storm	storm	NN
cord-344382-vge4ho2v	14	17	and	and	CC
cord-344382-vge4ho2v	14	18	a	a	DT
cord-344382-vge4ho2v	14	19	systemic	systemic	JJ
cord-344382-vge4ho2v	14	20	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	14	21	response	response	NN
cord-344382-vge4ho2v	14	22	resulting	result	VBG
cord-344382-vge4ho2v	14	23	from	from	IN
cord-344382-vge4ho2v	14	24	the	the	DT
cord-344382-vge4ho2v	14	25	release	release	NN
cord-344382-vge4ho2v	14	26	of	of	IN
cord-344382-vge4ho2v	14	27	large	large	JJ
cord-344382-vge4ho2v	14	28	amounts	amount	NNS
cord-344382-vge4ho2v	14	29	of	of	IN
cord-344382-vge4ho2v	14	30	pro	pro	JJ
cord-344382-vge4ho2v	14	31	-	-	JJ
cord-344382-vge4ho2v	14	32	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	14	33	cytokines	cytokine	NNS
cord-344382-vge4ho2v	14	34	and	and	CC
cord-344382-vge4ho2v	14	35	chemokines	chemokine	NNS
cord-344382-vge4ho2v	14	36	that	that	WDT
cord-344382-vge4ho2v	14	37	trigger	trigger	VBP
cord-344382-vge4ho2v	14	38	an	an	DT
cord-344382-vge4ho2v	14	39	attack	attack	NN
cord-344382-vge4ho2v	14	40	by	by	IN
cord-344382-vge4ho2v	14	41	the	the	DT
cord-344382-vge4ho2v	14	42	immune	immune	JJ
cord-344382-vge4ho2v	14	43	system	system	NN
cord-344382-vge4ho2v	14	44	.	.	.
cord-344382-vge4ho2v	15	1	2	2	LS
cord-344382-vge4ho2v	16	1	Besides	besides	IN
cord-344382-vge4ho2v	16	2	affecting	affect	VBG
cord-344382-vge4ho2v	16	3	the	the	DT
cord-344382-vge4ho2v	16	4	respiratory	respiratory	JJ
cord-344382-vge4ho2v	16	5	system	system	NN
cord-344382-vge4ho2v	16	6	,	,	,
cord-344382-vge4ho2v	16	7	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	16	8	affects	affect	VBZ
cord-344382-vge4ho2v	16	9	other	other	JJ
cord-344382-vge4ho2v	16	10	systems	system	NNS
cord-344382-vge4ho2v	16	11	,	,	,
cord-344382-vge4ho2v	16	12	also	also	RB
cord-344382-vge4ho2v	16	13	including	include	VBG
cord-344382-vge4ho2v	16	14	the	the	DT
cord-344382-vge4ho2v	16	15	cardiovascular	cardiovascular	JJ
cord-344382-vge4ho2v	16	16	system	system	NN
cord-344382-vge4ho2v	16	17	,	,	,
cord-344382-vge4ho2v	16	18	and	and	CC
cord-344382-vge4ho2v	16	19	diffuse	diffuse	VB
cord-344382-vge4ho2v	16	20	thrombosis	thrombosis	NN
cord-344382-vge4ho2v	16	21	is	be	VBZ
cord-344382-vge4ho2v	16	22	emerging	emerge	VBG
cord-344382-vge4ho2v	16	23	as	as	IN
cord-344382-vge4ho2v	16	24	an	an	DT
cord-344382-vge4ho2v	16	25	important	important	JJ
cord-344382-vge4ho2v	16	26	contributor	contributor	NN
cord-344382-vge4ho2v	16	27	to	to	IN
cord-344382-vge4ho2v	16	28	adverse	adverse	JJ
cord-344382-vge4ho2v	16	29	outcomes	outcome	NNS
cord-344382-vge4ho2v	16	30	in	in	IN
cord-344382-vge4ho2v	16	31	patients	patient	NNS
cord-344382-vge4ho2v	16	32	with	with	IN
cord-344382-vge4ho2v	16	33	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	16	34	.	.	.
cord-344382-vge4ho2v	17	1	Different	different	JJ
cord-344382-vge4ho2v	17	2	pathogenic	pathogenic	JJ
cord-344382-vge4ho2v	17	3	disturbances	disturbance	NNS
cord-344382-vge4ho2v	17	4	are	be	VBP
cord-344382-vge4ho2v	17	5	involved	involve	VBN
cord-344382-vge4ho2v	17	6	,	,	,
cord-344382-vge4ho2v	17	7	such	such	JJ
cord-344382-vge4ho2v	17	8	as	as	IN
cord-344382-vge4ho2v	17	9	acute	acute	JJ
cord-344382-vge4ho2v	17	10	changes	change	NNS
cord-344382-vge4ho2v	17	11	in	in	IN
cord-344382-vge4ho2v	17	12	myocardial	myocardial	JJ
cord-344382-vge4ho2v	17	13	demand	demand	NN
cord-344382-vge4ho2v	17	14	and	and	CC
cord-344382-vge4ho2v	17	15	supply	supply	NN
cord-344382-vge4ho2v	17	16	due	due	IN
cord-344382-vge4ho2v	17	17	to	to	IN
cord-344382-vge4ho2v	17	18	tachycardia	tachycardia	NN
cord-344382-vge4ho2v	17	19	,	,	,
cord-344382-vge4ho2v	17	20	hypotension	hypotension	NN
cord-344382-vge4ho2v	17	21	,	,	,
cord-344382-vge4ho2v	17	22	and	and	CC
cord-344382-vge4ho2v	17	23	hypoxemia	hypoxemia	NN
cord-344382-vge4ho2v	17	24	resulting	result	VBG
cord-344382-vge4ho2v	17	25	in	in	IN
cord-344382-vge4ho2v	17	26	type	type	NN
cord-344382-vge4ho2v	17	27	2	2	CD
cord-344382-vge4ho2v	17	28	myocardial	myocardial	JJ
cord-344382-vge4ho2v	17	29	infarction	infarction	NN
cord-344382-vge4ho2v	17	30	;	;	:
cord-344382-vge4ho2v	17	31	acute	acute	JJ
cord-344382-vge4ho2v	17	32	coronary	coronary	JJ
cord-344382-vge4ho2v	17	33	syndrome	syndrome	NN
cord-344382-vge4ho2v	17	34	due	due	IN
cord-344382-vge4ho2v	17	35	to	to	IN
cord-344382-vge4ho2v	17	36	acute	acute	JJ
cord-344382-vge4ho2v	17	37	atherothrombosis	atherothrombosis	NN
cord-344382-vge4ho2v	17	38	in	in	IN
cord-344382-vge4ho2v	17	39	a	a	DT
cord-344382-vge4ho2v	17	40	virally	virally	RB
cord-344382-vge4ho2v	17	41	induced	induce	VBN
cord-344382-vge4ho2v	17	42	thrombotic	thrombotic	JJ
cord-344382-vge4ho2v	17	43	and	and	CC
cord-344382-vge4ho2v	17	44	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	17	45	milieu	milieu	NN
cord-344382-vge4ho2v	17	46	;	;	:
cord-344382-vge4ho2v	17	47	microvascular	microvascular	JJ
cord-344382-vge4ho2v	17	48	dysfunction	dysfunction	NN
cord-344382-vge4ho2v	17	49	due	due	JJ
cord-344382-vge4ho2v	17	50	to	to	TO
cord-344382-vge4ho2v	17	51	diffuse	diffuse	VB
cord-344382-vge4ho2v	17	52	microthrombi	microthrombi	NNP
cord-344382-vge4ho2v	17	53	or	or	CC
cord-344382-vge4ho2v	17	54	vascular	vascular	JJ
cord-344382-vge4ho2v	17	55	injury	injury	NN
cord-344382-vge4ho2v	17	56	;	;	:
cord-344382-vge4ho2v	17	57	stress	stress	NN
cord-344382-vge4ho2v	17	58	-	-	HYPH
cord-344382-vge4ho2v	17	59	related	relate	VBN
cord-344382-vge4ho2v	17	60	cardiomyopathy	cardiomyopathy	NN
cord-344382-vge4ho2v	17	61	(	(	-LRB-
cord-344382-vge4ho2v	17	62	Takotsubo	Takotsubo	NNP
cord-344382-vge4ho2v	17	63	syndrome	syndrome	NN
cord-344382-vge4ho2v	17	64	)	)	-RRB-
cord-344382-vge4ho2v	17	65	;	;	,
cord-344382-vge4ho2v	17	66	direct	direct	JJ
cord-344382-vge4ho2v	17	67	viral	viral	JJ
cord-344382-vge4ho2v	17	68	cardiomyocyte	cardiomyocyte	NN
cord-344382-vge4ho2v	17	69	toxicity	toxicity	NN
cord-344382-vge4ho2v	17	70	and	and	CC
cord-344382-vge4ho2v	17	71	myocarditis	myocarditis	NN
cord-344382-vge4ho2v	17	72	.	.	.
cord-344382-vge4ho2v	18	1	3	3	LS
cord-344382-vge4ho2v	19	1	All	all	DT
cord-344382-vge4ho2v	19	2	of	of	IN
cord-344382-vge4ho2v	19	3	these	these	DT
cord-344382-vge4ho2v	19	4	complications	complication	NNS
cord-344382-vge4ho2v	19	5	reflect	reflect	VBP
cord-344382-vge4ho2v	19	6	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	19	7	reactions	reaction	NNS
cord-344382-vge4ho2v	19	8	stimulated	stimulate	VBN
cord-344382-vge4ho2v	19	9	by	by	IN
cord-344382-vge4ho2v	19	10	the	the	DT
cord-344382-vge4ho2v	19	11	viral	viral	JJ
cord-344382-vge4ho2v	19	12	infection	infection	NN
cord-344382-vge4ho2v	19	13	.	.	.
cord-344382-vge4ho2v	20	1	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	20	2	is	be	VBZ
cord-344382-vge4ho2v	20	3	particularly	particularly	RB
cord-344382-vge4ho2v	20	4	severe	severe	JJ
cord-344382-vge4ho2v	20	5	in	in	IN
cord-344382-vge4ho2v	20	6	individuals	individual	NNS
cord-344382-vge4ho2v	20	7	who	who	WP
cord-344382-vge4ho2v	20	8	are	be	VBP
cord-344382-vge4ho2v	20	9	at	at	IN
cord-344382-vge4ho2v	20	10	risk	risk	NN
cord-344382-vge4ho2v	20	11	either	either	CC
cord-344382-vge4ho2v	20	12	because	because	IN
cord-344382-vge4ho2v	20	13	of	of	IN
cord-344382-vge4ho2v	20	14	old	old	JJ
cord-344382-vge4ho2v	20	15	age	age	NN
cord-344382-vge4ho2v	20	16	or	or	CC
cord-344382-vge4ho2v	20	17	of	of	IN
cord-344382-vge4ho2v	20	18	pre	pre	JJ
cord-344382-vge4ho2v	20	19	-	-	JJ
cord-344382-vge4ho2v	20	20	existing	existing	JJ
cord-344382-vge4ho2v	20	21	pathological	pathological	JJ
cord-344382-vge4ho2v	20	22	conditions	condition	NNS
cord-344382-vge4ho2v	20	23	.	.	.
cord-344382-vge4ho2v	21	1	For	for	IN
cord-344382-vge4ho2v	21	2	instance	instance	NN
cord-344382-vge4ho2v	21	3	,	,	,
cord-344382-vge4ho2v	21	4	in	in	IN
cord-344382-vge4ho2v	21	5	Italy	Italy	NNP
cord-344382-vge4ho2v	21	6	the	the	DT
cord-344382-vge4ho2v	21	7	mean	mean	JJ
cord-344382-vge4ho2v	21	8	age	age	NN
cord-344382-vge4ho2v	21	9	of	of	IN
cord-344382-vge4ho2v	21	10	patients	patient	NNS
cord-344382-vge4ho2v	21	11	dying	die	VBG
cord-344382-vge4ho2v	21	12	of	of	IN
cord-344382-vge4ho2v	21	13	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	21	14	as	as	IN
cord-344382-vge4ho2v	21	15	of	of	IN
cord-344382-vge4ho2v	21	16	May	May	NNP
cord-344382-vge4ho2v	21	17	28	28	CD
cord-344382-vge4ho2v	21	18	was	be	VBD
cord-344382-vge4ho2v	21	19	80	80	CD
cord-344382-vge4ho2v	21	20	years	year	NNS
cord-344382-vge4ho2v	21	21	,	,	,
cord-344382-vge4ho2v	21	22	and	and	CC
cord-344382-vge4ho2v	21	23	95.9	95.9	CD
cord-344382-vge4ho2v	21	24	%	%	NN
cord-344382-vge4ho2v	21	25	of	of	IN
cord-344382-vge4ho2v	21	26	deceased	deceased	JJ
cord-344382-vge4ho2v	21	27	persons	person	NNS
cord-344382-vge4ho2v	21	28	had	have	VBD
cord-344382-vge4ho2v	21	29	important	important	JJ
cord-344382-vge4ho2v	21	30	pre	pre	JJ
cord-344382-vge4ho2v	21	31	-	-	JJ
cord-344382-vge4ho2v	21	32	existing	existing	JJ
cord-344382-vge4ho2v	21	33	conditions	condition	NNS
cord-344382-vge4ho2v	21	34	,	,	,
cord-344382-vge4ho2v	21	35	such	such	JJ
cord-344382-vge4ho2v	21	36	as	as	IN
cord-344382-vge4ho2v	21	37	cardiovascular	cardiovascular	JJ
cord-344382-vge4ho2v	21	38	diseases	disease	NNS
cord-344382-vge4ho2v	21	39	,	,	,
cord-344382-vge4ho2v	21	40	cerebrovascular	cerebrovascular	JJ
cord-344382-vge4ho2v	21	41	diseases	disease	NNS
cord-344382-vge4ho2v	21	42	,	,	,
cord-344382-vge4ho2v	21	43	diabetes	diabetes	NN
cord-344382-vge4ho2v	21	44	,	,	,
cord-344382-vge4ho2v	21	45	dementia	dementia	NN
cord-344382-vge4ho2v	21	46	,	,	,
cord-344382-vge4ho2v	21	47	chronic	chronic	JJ
cord-344382-vge4ho2v	21	48	obstructive	obstructive	JJ
cord-344382-vge4ho2v	21	49	pulmonary	pulmonary	JJ
cord-344382-vge4ho2v	21	50	diseases	disease	NNS
cord-344382-vge4ho2v	21	51	(	(	-LRB-
cord-344382-vge4ho2v	21	52	COPD	COPD	NNP
cord-344382-vge4ho2v	21	53	)	)	-RRB-
cord-344382-vge4ho2v	21	54	,	,	,
cord-344382-vge4ho2v	21	55	cancer	cancer	NN
cord-344382-vge4ho2v	21	56	,	,	,
cord-344382-vge4ho2v	21	57	chronic	chronic	JJ
cord-344382-vge4ho2v	21	58	liver	liver	NN
cord-344382-vge4ho2v	21	59	disease	disease	NN
cord-344382-vge4ho2v	21	60	,	,	,
cord-344382-vge4ho2v	21	61	chronic	chronic	JJ
cord-344382-vge4ho2v	21	62	renal	renal	JJ
cord-344382-vge4ho2v	21	63	failure	failure	NN
cord-344382-vge4ho2v	21	64	,	,	,
cord-344382-vge4ho2v	21	65	respiratory	respiratory	JJ
cord-344382-vge4ho2v	21	66	failure	failure	NN
cord-344382-vge4ho2v	21	67	,	,	,
cord-344382-vge4ho2v	21	68	human	human	JJ
cord-344382-vge4ho2v	21	69	immunodeficiency	immunodeficiency	NN
cord-344382-vge4ho2v	21	70	virus	virus	NN
cord-344382-vge4ho2v	21	71	(	(	-LRB-
cord-344382-vge4ho2v	21	72	HIV	HIV	NNP
cord-344382-vge4ho2v	21	73	)	)	-RRB-
cord-344382-vge4ho2v	21	74	infection	infection	NN
cord-344382-vge4ho2v	21	75	,	,	,
cord-344382-vge4ho2v	21	76	autoimmune	autoimmune	JJ
cord-344382-vge4ho2v	21	77	diseases	disease	NNS
cord-344382-vge4ho2v	21	78	,	,	,
cord-344382-vge4ho2v	21	79	and	and	CC
cord-344382-vge4ho2v	21	80	obesity	obesity	NN
cord-344382-vge4ho2v	21	81	.	.	.
cord-344382-vge4ho2v	22	1	Specifically	specifically	RB
cord-344382-vge4ho2v	22	2	,	,	,
cord-344382-vge4ho2v	22	3	14.9	14.9	CD
cord-344382-vge4ho2v	22	4	%	%	NN
cord-344382-vge4ho2v	22	5	had	have	VBD
cord-344382-vge4ho2v	22	6	a	a	DT
cord-344382-vge4ho2v	22	7	single	single	JJ
cord-344382-vge4ho2v	22	8	comorbidity	comorbidity	NN
cord-344382-vge4ho2v	22	9	,	,	,
cord-344382-vge4ho2v	22	10	21.5	21.5	CD
cord-344382-vge4ho2v	22	11	%	%	NN
cord-344382-vge4ho2v	22	12	had	have	VBD
cord-344382-vge4ho2v	22	13	2	2	CD
cord-344382-vge4ho2v	22	14	comorbidities	comorbiditie	NNS
cord-344382-vge4ho2v	22	15	,	,	,
cord-344382-vge4ho2v	22	16	and	and	CC
cord-344382-vge4ho2v	22	17	59.5	59.5	CD
cord-344382-vge4ho2v	22	18	%	%	NN
cord-344382-vge4ho2v	22	19	had	have	VBD
cord-344382-vge4ho2v	22	20	3	3	CD
cord-344382-vge4ho2v	22	21	or	or	CC
cord-344382-vge4ho2v	22	22	more	more	JJR
cord-344382-vge4ho2v	22	23	comorbidities	comorbiditie	NNS
cord-344382-vge4ho2v	22	24	,	,	,
cord-344382-vge4ho2v	22	25	with	with	IN
cord-344382-vge4ho2v	22	26	a	a	DT
cord-344382-vge4ho2v	22	27	mean	mean	JJ
cord-344382-vge4ho2v	22	28	number	number	NN
cord-344382-vge4ho2v	22	29	of	of	IN
cord-344382-vge4ho2v	22	30	3.3	3.3	CD
cord-344382-vge4ho2v	22	31	comorbidities	comorbiditie	NNS
cord-344382-vge4ho2v	22	32	.	.	.
cord-344382-vge4ho2v	23	1	4	4	LS
cord-344382-vge4ho2v	23	2	Especially	especially	RB
cord-344382-vge4ho2v	23	3	in	in	IN
cord-344382-vge4ho2v	23	4	patients	patient	NNS
cord-344382-vge4ho2v	23	5	below	below	IN
cord-344382-vge4ho2v	23	6	the	the	DT
cord-344382-vge4ho2v	23	7	age	age	NN
cord-344382-vge4ho2v	23	8	of	of	IN
cord-344382-vge4ho2v	23	9	80	80	CD
cord-344382-vge4ho2v	23	10	,	,	,
cord-344382-vge4ho2v	23	11	the	the	DT
cord-344382-vge4ho2v	23	12	fatal	fatal	JJ
cord-344382-vge4ho2v	23	13	cases	case	NNS
cord-344382-vge4ho2v	23	14	were	be	VBD
cord-344382-vge4ho2v	23	15	much	much	RB
cord-344382-vge4ho2v	23	16	more	more	RBR
cord-344382-vge4ho2v	23	17	frequent	frequent	JJ
cord-344382-vge4ho2v	23	18	in	in	IN
cord-344382-vge4ho2v	23	19	men	man	NNS
cord-344382-vge4ho2v	23	20	,	,	,
cord-344382-vge4ho2v	23	21	4	4	CD
cord-344382-vge4ho2v	23	22	who	who	WP
cord-344382-vge4ho2v	23	23	have	have	VBP
cord-344382-vge4ho2v	23	24	lower	low	JJR
cord-344382-vge4ho2v	23	25	levels	level	NNS
cord-344382-vge4ho2v	23	26	of	of	IN
cord-344382-vge4ho2v	23	27	blood	blood	NN
cord-344382-vge4ho2v	23	28	reduced	reduce	VBN
cord-344382-vge4ho2v	23	29	glutathione	glutathione	NN
cord-344382-vge4ho2v	23	30	(	(	-LRB-
cord-344382-vge4ho2v	23	31	GSH	GSH	NNP
cord-344382-vge4ho2v	23	32	)	)	-RRB-
cord-344382-vge4ho2v	23	33	.	.	.
cord-344382-vge4ho2v	24	1	5	5	LS
cord-344382-vge4ho2v	24	2	Elderly	elderly	JJ
cord-344382-vge4ho2v	24	3	individuals	individual	NNS
cord-344382-vge4ho2v	24	4	maintain	maintain	VBP
cord-344382-vge4ho2v	24	5	a	a	DT
cord-344382-vge4ho2v	24	6	chronic	chronic	JJ
cord-344382-vge4ho2v	24	7	low	low	JJ
cord-344382-vge4ho2v	24	8	level	level	NN
cord-344382-vge4ho2v	24	9	of	of	IN
cord-344382-vge4ho2v	24	10	inflammation	inflammation	NN
cord-344382-vge4ho2v	24	11	that	that	WDT
cord-344382-vge4ho2v	24	12	is	be	VBZ
cord-344382-vge4ho2v	24	13	associated	associate	VBN
cord-344382-vge4ho2v	24	14	with	with	IN
cord-344382-vge4ho2v	24	15	oxidative	oxidative	JJ
cord-344382-vge4ho2v	24	16	stress	stress	NN
cord-344382-vge4ho2v	24	17	and	and	CC
cord-344382-vge4ho2v	24	18	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	24	19	cytokine	cytokine	NN
cord-344382-vge4ho2v	24	20	production	production	NN
cord-344382-vge4ho2v	24	21	,	,	,
cord-344382-vge4ho2v	24	22	a	a	DT
cord-344382-vge4ho2v	24	23	condition	condition	NN
cord-344382-vge4ho2v	24	24	that	that	WDT
cord-344382-vge4ho2v	24	25	increases	increase	VBZ
cord-344382-vge4ho2v	24	26	the	the	DT
cord-344382-vge4ho2v	24	27	severity	severity	NN
cord-344382-vge4ho2v	24	28	of	of	IN
cord-344382-vge4ho2v	24	29	viral	viral	JJ
cord-344382-vge4ho2v	24	30	infections	infection	NNS
cord-344382-vge4ho2v	24	31	in	in	IN
cord-344382-vge4ho2v	24	32	this	this	DT
cord-344382-vge4ho2v	24	33	population	population	NN
cord-344382-vge4ho2v	24	34	and	and	CC
cord-344382-vge4ho2v	24	35	that	that	DT
cord-344382-vge4ho2v	24	36	could	could	MD
cord-344382-vge4ho2v	24	37	be	be	VB
cord-344382-vge4ho2v	24	38	attenuated	attenuate	VBN
cord-344382-vge4ho2v	24	39	by	by	IN
cord-344382-vge4ho2v	24	40	administration	administration	NN
cord-344382-vge4ho2v	24	41	of	of	IN
cord-344382-vge4ho2v	24	42	antioxidants	antioxidant	NNS
cord-344382-vge4ho2v	24	43	.	.	.
cord-344382-vge4ho2v	25	1	6	6	CD
cord-344382-vge4ho2v	26	1	A	a	DT
cord-344382-vge4ho2v	26	2	significant	significant	JJ
cord-344382-vge4ho2v	26	3	elevation	elevation	NN
cord-344382-vge4ho2v	26	4	in	in	IN
cord-344382-vge4ho2v	26	5	blood	blood	NN
cord-344382-vge4ho2v	26	6	serum	serum	NN
cord-344382-vge4ho2v	26	7	glutathione	glutathione	NN
cord-344382-vge4ho2v	26	8	reductase	reductase	NN
cord-344382-vge4ho2v	26	9	(	(	-LRB-
cord-344382-vge4ho2v	26	10	GR	GR	NNP
cord-344382-vge4ho2v	26	11	)	)	-RRB-
cord-344382-vge4ho2v	26	12	,	,	,
cord-344382-vge4ho2v	26	13	resulting	result	VBG
cord-344382-vge4ho2v	26	14	from	from	IN
cord-344382-vge4ho2v	26	15	oxidative	oxidative	JJ
cord-344382-vge4ho2v	26	16	stress	stress	NN
cord-344382-vge4ho2v	26	17	imbalance	imbalance	NN
cord-344382-vge4ho2v	26	18	,	,	,
cord-344382-vge4ho2v	26	19	was	be	VBD
cord-344382-vge4ho2v	26	20	detected	detect	VBN
cord-344382-vge4ho2v	26	21	in	in	IN
cord-344382-vge4ho2v	26	22	COVID-19	covid-19	JJ
cord-344382-vge4ho2v	26	23	patients	patient	NNS
cord-344382-vge4ho2v	26	24	,	,	,
cord-344382-vge4ho2v	26	25	especially	especially	RB
cord-344382-vge4ho2v	26	26	when	when	WRB
cord-344382-vge4ho2v	26	27	admitted	admit	VBN
cord-344382-vge4ho2v	26	28	to	to	IN
cord-344382-vge4ho2v	26	29	ICU	ICU	NNP
cord-344382-vge4ho2v	26	30	.	.	.
cord-344382-vge4ho2v	27	1	7	7	CD
cord-344382-vge4ho2v	28	1	From	from	IN
cord-344382-vge4ho2v	28	2	an	an	DT
cord-344382-vge4ho2v	28	3	accumulation	accumulation	NN
cord-344382-vge4ho2v	28	4	of	of	IN
cord-344382-vge4ho2v	28	5	literature	literature	NN
cord-344382-vge4ho2v	28	6	data	datum	NNS
cord-344382-vge4ho2v	28	7	,	,	,
cord-344382-vge4ho2v	28	8	an	an	DT
cord-344382-vge4ho2v	28	9	endogenous	endogenous	JJ
cord-344382-vge4ho2v	28	10	deficiency	deficiency	NN
cord-344382-vge4ho2v	28	11	in	in	IN
cord-344382-vge4ho2v	28	12	GSH	GSH	NNP
cord-344382-vge4ho2v	28	13	may	may	MD
cord-344382-vge4ho2v	28	14	underlie	underlie	VB
cord-344382-vge4ho2v	28	15	the	the	DT
cord-344382-vge4ho2v	28	16	serious	serious	JJ
cord-344382-vge4ho2v	28	17	manifestations	manifestation	NNS
cord-344382-vge4ho2v	28	18	and	and	CC
cord-344382-vge4ho2v	28	19	death	death	NN
cord-344382-vge4ho2v	28	20	from	from	IN
cord-344382-vge4ho2v	28	21	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	28	22	.	.	.
cord-344382-vge4ho2v	28	23	8	8	CD
cord-344382-vge4ho2v	29	1	As	as	IN
cord-344382-vge4ho2v	29	2	we	-PRON-	PRP
cord-344382-vge4ho2v	29	3	will	will	MD
cord-344382-vge4ho2v	29	4	discuss	discuss	VB
cord-344382-vge4ho2v	29	5	below	below	RB
cord-344382-vge4ho2v	29	6	,	,	,
cord-344382-vge4ho2v	29	7	N	n	CD
cord-344382-vge4ho2v	29	8	-	-	HYPH
cord-344382-vge4ho2v	29	9	acetyl	acetyl	NNP
cord-344382-vge4ho2v	29	10	-	-	HYPH
cord-344382-vge4ho2v	29	11	L	l	NN
cord-344382-vge4ho2v	29	12	-	-	HYPH
cord-344382-vge4ho2v	29	13	cysteine	cysteine	NN
cord-344382-vge4ho2v	29	14	(	(	-LRB-
cord-344382-vge4ho2v	29	15	NAC	NAC	NNP
cord-344382-vge4ho2v	29	16	)	)	-RRB-
cord-344382-vge4ho2v	29	17	is	be	VBZ
cord-344382-vge4ho2v	29	18	used	use	VBN
cord-344382-vge4ho2v	29	19	in	in	IN
cord-344382-vge4ho2v	29	20	a	a	DT
cord-344382-vge4ho2v	29	21	broad	broad	JJ
cord-344382-vge4ho2v	29	22	range	range	NN
cord-344382-vge4ho2v	29	23	of	of	IN
cord-344382-vge4ho2v	29	24	conditions	condition	NNS
cord-344382-vge4ho2v	29	25	to	to	TO
cord-344382-vge4ho2v	29	26	restore	restore	VB
cord-344382-vge4ho2v	29	27	or	or	CC
cord-344382-vge4ho2v	29	28	protect	protect	VB
cord-344382-vge4ho2v	29	29	against	against	IN
cord-344382-vge4ho2v	29	30	GSH	GSH	NNP
cord-344382-vge4ho2v	29	31	depletion	depletion	NN
cord-344382-vge4ho2v	29	32	and	and	CC
cord-344382-vge4ho2v	29	33	has	have	VBZ
cord-344382-vge4ho2v	29	34	a	a	DT
cord-344382-vge4ho2v	29	35	wide	wide	JJ
cord-344382-vge4ho2v	29	36	safety	safety	NN
cord-344382-vge4ho2v	29	37	margin	margin	NN
cord-344382-vge4ho2v	29	38	.	.	.
cord-344382-vge4ho2v	30	1	It	-PRON-	PRP
cord-344382-vge4ho2v	30	2	has	have	VBZ
cord-344382-vge4ho2v	30	3	been	be	VBN
cord-344382-vge4ho2v	30	4	of	of	IN
cord-344382-vge4ho2v	30	5	benefit	benefit	NN
cord-344382-vge4ho2v	30	6	in	in	IN
cord-344382-vge4ho2v	30	7	treating	treat	VBG
cord-344382-vge4ho2v	30	8	ARDS	ARDS	NNP
cord-344382-vge4ho2v	30	9	from	from	IN
cord-344382-vge4ho2v	30	10	other	other	JJ
cord-344382-vge4ho2v	30	11	causes	cause	NNS
cord-344382-vge4ho2v	30	12	and	and	CC
cord-344382-vge4ho2v	30	13	might	may	MD
cord-344382-vge4ho2v	30	14	limit	limit	VB
cord-344382-vge4ho2v	30	15	or	or	CC
cord-344382-vge4ho2v	30	16	prevent	prevent	VB
cord-344382-vge4ho2v	30	17	lung	lung	NN
cord-344382-vge4ho2v	30	18	damage	damage	NN
cord-344382-vge4ho2v	30	19	in	in	IN
cord-344382-vge4ho2v	30	20	patients	patient	NNS
cord-344382-vge4ho2v	30	21	with	with	IN
cord-344382-vge4ho2v	30	22	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	30	23	.	.	.
cord-344382-vge4ho2v	31	1	The	the	DT
cord-344382-vge4ho2v	31	2	evidence	evidence	NN
cord-344382-vge4ho2v	31	3	for	for	IN
cord-344382-vge4ho2v	31	4	this	this	DT
cord-344382-vge4ho2v	31	5	proposal	proposal	NN
cord-344382-vge4ho2v	31	6	is	be	VBZ
cord-344382-vge4ho2v	31	7	reviewed	review	VBN
cord-344382-vge4ho2v	31	8	here	here	RB
cord-344382-vge4ho2v	31	9	.	.	.
cord-344382-vge4ho2v	32	1	The	the	DT
cord-344382-vge4ho2v	32	2	angiotensin	angiotensin	NN
cord-344382-vge4ho2v	32	3	-	-	HYPH
cord-344382-vge4ho2v	32	4	converting	convert	VBG
cord-344382-vge4ho2v	32	5	enzyme	enzyme	NN
cord-344382-vge4ho2v	32	6	2	2	CD
cord-344382-vge4ho2v	32	7	(	(	-LRB-
cord-344382-vge4ho2v	32	8	ACE2	ACE2	NNP
cord-344382-vge4ho2v	32	9	)	)	-RRB-
cord-344382-vge4ho2v	32	10	is	be	VBZ
cord-344382-vge4ho2v	32	11	the	the	DT
cord-344382-vge4ho2v	32	12	functional	functional	JJ
cord-344382-vge4ho2v	32	13	receptor	receptor	NN
cord-344382-vge4ho2v	32	14	for	for	IN
cord-344382-vge4ho2v	32	15	severe	severe	JJ
cord-344382-vge4ho2v	32	16	acute	acute	JJ
cord-344382-vge4ho2v	32	17	respiratory	respiratory	JJ
cord-344382-vge4ho2v	32	18	syndrome	syndrome	NN
cord-344382-vge4ho2v	32	19	(	(	-LRB-
cord-344382-vge4ho2v	32	20	SARS	SARS	NNP
cord-344382-vge4ho2v	32	21	)	)	-RRB-
cord-344382-vge4ho2v	32	22	coronaviruses	coronaviruses	NNP
cord-344382-vge4ho2v	32	23	,	,	,
cord-344382-vge4ho2v	32	24	responsible	responsible	JJ
cord-344382-vge4ho2v	32	25	for	for	IN
cord-344382-vge4ho2v	32	26	entrance	entrance	NN
cord-344382-vge4ho2v	32	27	into	into	IN
cord-344382-vge4ho2v	32	28	cells	cell	NNS
cord-344382-vge4ho2v	32	29	of	of	IN
cord-344382-vge4ho2v	32	30	both	both	DT
cord-344382-vge4ho2v	32	31	SARS	SARS	NNP
cord-344382-vge4ho2v	32	32	-	-	HYPH
cord-344382-vge4ho2v	32	33	CoV	CoV	NNP
cord-344382-vge4ho2v	32	34	and	and	CC
cord-344382-vge4ho2v	32	35	SARS	SARS	NNP
cord-344382-vge4ho2v	32	36	-	-	HYPH
cord-344382-vge4ho2v	32	37	CoV-2	CoV-2	NNP
cord-344382-vge4ho2v	32	38	,	,	,
cord-344382-vge4ho2v	32	39	the	the	DT
cord-344382-vge4ho2v	32	40	etiological	etiological	JJ
cord-344382-vge4ho2v	32	41	agent	agent	NN
cord-344382-vge4ho2v	32	42	of	of	IN
cord-344382-vge4ho2v	32	43	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	32	44	.	.	.
cord-344382-vge4ho2v	33	1	9	9	CD
cord-344382-vge4ho2v	34	1	Therefore	therefore	RB
cord-344382-vge4ho2v	34	2	,	,	,
cord-344382-vge4ho2v	34	3	the	the	DT
cord-344382-vge4ho2v	34	4	interaction	interaction	NN
cord-344382-vge4ho2v	34	5	of	of	IN
cord-344382-vge4ho2v	34	6	viral	viral	JJ
cord-344382-vge4ho2v	34	7	spike	spike	NN
cord-344382-vge4ho2v	34	8	proteins	protein	NNS
cord-344382-vge4ho2v	34	9	with	with	IN
cord-344382-vge4ho2v	34	10	ACE2	ACE2	NNP
cord-344382-vge4ho2v	34	11	is	be	VBZ
cord-344382-vge4ho2v	34	12	a	a	DT
cord-344382-vge4ho2v	34	13	critical	critical	JJ
cord-344382-vge4ho2v	34	14	step	step	NN
cord-344382-vge4ho2v	34	15	in	in	IN
cord-344382-vge4ho2v	34	16	the	the	DT
cord-344382-vge4ho2v	34	17	viral	viral	JJ
cord-344382-vge4ho2v	34	18	replication	replication	NN
cord-344382-vge4ho2v	34	19	cycle	cycle	NN
cord-344382-vge4ho2v	34	20	.	.	.
cord-344382-vge4ho2v	35	1	The	the	DT
cord-344382-vge4ho2v	35	2	receptor	receptor	NN
cord-344382-vge4ho2v	35	3	binding	bind	VBG
cord-344382-vge4ho2v	35	4	domain	domain	NN
cord-344382-vge4ho2v	35	5	of	of	IN
cord-344382-vge4ho2v	35	6	the	the	DT
cord-344382-vge4ho2v	35	7	viral	viral	JJ
cord-344382-vge4ho2v	35	8	spike	spike	NN
cord-344382-vge4ho2v	35	9	proteins	protein	NNS
cord-344382-vge4ho2v	35	10	and	and	CC
cord-344382-vge4ho2v	35	11	ACE2	ACE2	NNP
cord-344382-vge4ho2v	35	12	has	have	VBZ
cord-344382-vge4ho2v	35	13	several	several	JJ
cord-344382-vge4ho2v	35	14	cysteine	cysteine	NN
cord-344382-vge4ho2v	35	15	residues	residue	NNS
cord-344382-vge4ho2v	35	16	.	.	.
cord-344382-vge4ho2v	36	1	Molecular	molecular	JJ
cord-344382-vge4ho2v	36	2	dynamic	dynamic	JJ
cord-344382-vge4ho2v	36	3	simulations	simulation	NNS
cord-344382-vge4ho2v	36	4	showed	show	VBD
cord-344382-vge4ho2v	36	5	that	that	IN
cord-344382-vge4ho2v	36	6	the	the	DT
cord-344382-vge4ho2v	36	7	binding	bind	VBG
cord-344382-vge4ho2v	36	8	affinity	affinity	NN
cord-344382-vge4ho2v	36	9	was	be	VBD
cord-344382-vge4ho2v	36	10	significantly	significantly	RB
cord-344382-vge4ho2v	36	11	impaired	impair	VBN
cord-344382-vge4ho2v	36	12	when	when	WRB
cord-344382-vge4ho2v	36	13	all	all	PDT
cord-344382-vge4ho2v	36	14	the	the	DT
cord-344382-vge4ho2v	36	15	disulfide	disulfide	JJ
cord-344382-vge4ho2v	36	16	bonds	bond	NNS
cord-344382-vge4ho2v	36	17	of	of	IN
cord-344382-vge4ho2v	36	18	both	both	CC
cord-344382-vge4ho2v	36	19	ACE2	ACE2	NNP
cord-344382-vge4ho2v	36	20	and	and	CC
cord-344382-vge4ho2v	36	21	SARS	SARS	NNP
cord-344382-vge4ho2v	36	22	-	-	HYPH
cord-344382-vge4ho2v	36	23	CoV	CoV	NNP
cord-344382-vge4ho2v	36	24	/	/	,
cord-344382-vge4ho2v	36	25	CoV-2	CoV-2	NNP
cord-344382-vge4ho2v	36	26	spike	spike	NN
cord-344382-vge4ho2v	36	27	proteins	protein	NNS
cord-344382-vge4ho2v	36	28	were	be	VBD
cord-344382-vge4ho2v	36	29	reduced	reduce	VBN
cord-344382-vge4ho2v	36	30	to	to	IN
cord-344382-vge4ho2v	36	31	thiol	thiol	NN
cord-344382-vge4ho2v	36	32	groups	group	NNS
cord-344382-vge4ho2v	36	33	.	.	.
cord-344382-vge4ho2v	37	1	These	these	DT
cord-344382-vge4ho2v	37	2	findings	finding	NNS
cord-344382-vge4ho2v	37	3	are	be	VBP
cord-344382-vge4ho2v	37	4	consistent	consistent	JJ
cord-344382-vge4ho2v	37	5	with	with	IN
cord-344382-vge4ho2v	37	6	the	the	DT
cord-344382-vge4ho2v	37	7	view	view	NN
cord-344382-vge4ho2v	37	8	that	that	IN
cord-344382-vge4ho2v	37	9	the	the	DT
cord-344382-vge4ho2v	37	10	reduction	reduction	NN
cord-344382-vge4ho2v	37	11	of	of	IN
cord-344382-vge4ho2v	37	12	disulfides	disulfide	NNS
cord-344382-vge4ho2v	37	13	into	into	IN
cord-344382-vge4ho2v	37	14	sulfhydryl	sulfhydryl	NN
cord-344382-vge4ho2v	37	15	groups	group	NNS
cord-344382-vge4ho2v	37	16	completely	completely	RB
cord-344382-vge4ho2v	37	17	impairs	impair	VBZ
cord-344382-vge4ho2v	37	18	the	the	DT
cord-344382-vge4ho2v	37	19	binding	binding	NN
cord-344382-vge4ho2v	37	20	of	of	IN
cord-344382-vge4ho2v	37	21	SARS	SARS	NNP
cord-344382-vge4ho2v	37	22	-	-	HYPH
cord-344382-vge4ho2v	37	23	CoV	CoV	NNP
cord-344382-vge4ho2v	37	24	/	/	,
cord-344382-vge4ho2v	37	25	CoV-2	CoV-2	NNP
cord-344382-vge4ho2v	37	26	spike	spike	NN
cord-344382-vge4ho2v	37	27	protein	protein	NN
cord-344382-vge4ho2v	37	28	to	to	IN
cord-344382-vge4ho2v	37	29	ACE2	ACE2	NNP
cord-344382-vge4ho2v	37	30	(	(	-LRB-
cord-344382-vge4ho2v	37	31	see	see	VB
cord-344382-vge4ho2v	37	32	Figure	figure	NN
cord-344382-vge4ho2v	37	33	1	1	CD
cord-344382-vge4ho2v	37	34	)	)	-RRB-
cord-344382-vge4ho2v	37	35	and	and	CC
cord-344382-vge4ho2v	37	36	provide	provide	VB
cord-344382-vge4ho2v	37	37	a	a	DT
cord-344382-vge4ho2v	37	38	molecular	molecular	JJ
cord-344382-vge4ho2v	37	39	basis	basis	NN
cord-344382-vge4ho2v	37	40	for	for	IN
cord-344382-vge4ho2v	37	41	the	the	DT
cord-344382-vge4ho2v	37	42	severity	severity	NN
cord-344382-vge4ho2v	37	43	of	of	IN
cord-344382-vge4ho2v	37	44	COVID-19	covid-19	JJ
cord-344382-vge4ho2v	37	45	infection	infection	NN
cord-344382-vge4ho2v	37	46	due	due	IN
cord-344382-vge4ho2v	37	47	to	to	IN
cord-344382-vge4ho2v	37	48	oxidative	oxidative	JJ
cord-344382-vge4ho2v	37	49	stress	stress	NN
cord-344382-vge4ho2v	37	50	.	.	.
cord-344382-vge4ho2v	38	1	10	10	CD
cord-344382-vge4ho2v	39	1	Furthermore	furthermore	RB
cord-344382-vge4ho2v	39	2	,	,	,
cord-344382-vge4ho2v	39	3	both	both	DT
cord-344382-vge4ho2v	39	4	animal	animal	NN
cord-344382-vge4ho2v	39	5	studies	study	NNS
cord-344382-vge4ho2v	39	6	and	and	CC
cord-344382-vge4ho2v	39	7	clinical	clinical	JJ
cord-344382-vge4ho2v	39	8	studies	study	NNS
cord-344382-vge4ho2v	39	9	suggested	suggest	VBD
cord-344382-vge4ho2v	39	10	that	that	IN
cord-344382-vge4ho2v	39	11	supplementation	supplementation	NN
cord-344382-vge4ho2v	39	12	of	of	IN
cord-344382-vge4ho2v	39	13	NAC	NAC	NNP
cord-344382-vge4ho2v	39	14	,	,	,
cord-344382-vge4ho2v	39	15	which	which	WDT
cord-344382-vge4ho2v	39	16	is	be	VBZ
cord-344382-vge4ho2v	39	17	known	know	VBN
cord-344382-vge4ho2v	39	18	to	to	TO
cord-344382-vge4ho2v	39	19	attenuate	attenuate	VB
cord-344382-vge4ho2v	39	20	the	the	DT
cord-344382-vge4ho2v	39	21	tolerance	tolerance	NN
cord-344382-vge4ho2v	39	22	to	to	IN
cord-344382-vge4ho2v	39	23	nitrates	nitrate	NNS
cord-344382-vge4ho2v	39	24	,	,	,
cord-344382-vge4ho2v	39	25	modifies	modify	VBZ
cord-344382-vge4ho2v	39	26	the	the	DT
cord-344382-vge4ho2v	39	27	function	function	NN
cord-344382-vge4ho2v	39	28	of	of	IN
cord-344382-vge4ho2v	39	29	the	the	DT
cord-344382-vge4ho2v	39	30	renin	renin	NN
cord-344382-vge4ho2v	39	31	/	/	SYM
cord-344382-vge4ho2v	39	32	angiotensin	angiotensin	NN
cord-344382-vge4ho2v	39	33	system	system	NN
cord-344382-vge4ho2v	39	34	in	in	IN
cord-344382-vge4ho2v	39	35	vivo	vivo	NNP
cord-344382-vge4ho2v	39	36	.	.	.
cord-344382-vge4ho2v	40	1	Such	such	PDT
cord-344382-vge4ho2v	40	2	an	an	DT
cord-344382-vge4ho2v	40	3	effect	effect	NN
cord-344382-vge4ho2v	40	4	is	be	VBZ
cord-344382-vge4ho2v	40	5	probably	probably	RB
cord-344382-vge4ho2v	40	6	mediated	mediate	VBN
cord-344382-vge4ho2v	40	7	by	by	IN
cord-344382-vge4ho2v	40	8	inhibition	inhibition	NN
cord-344382-vge4ho2v	40	9	of	of	IN
cord-344382-vge4ho2v	40	10	ACE	ace	NN
cord-344382-vge4ho2v	40	11	activity	activity	NN
cord-344382-vge4ho2v	40	12	.	.	.
cord-344382-vge4ho2v	41	1	11	11	CD
cord-344382-vge4ho2v	42	1	By	by	IN
cord-344382-vge4ho2v	42	2	blocking	block	VBG
cord-344382-vge4ho2v	42	3	ACE	ACE	NNP
cord-344382-vge4ho2v	42	4	,	,	,
cord-344382-vge4ho2v	42	5	NAC	NAC	NNP
cord-344382-vge4ho2v	42	6	may	may	MD
cord-344382-vge4ho2v	42	7	provide	provide	VB
cord-344382-vge4ho2v	42	8	protection	protection	NN
cord-344382-vge4ho2v	42	9	from	from	IN
cord-344382-vge4ho2v	42	10	the	the	DT
cord-344382-vge4ho2v	42	11	deleterious	deleterious	JJ
cord-344382-vge4ho2v	42	12	effects	effect	NNS
cord-344382-vge4ho2v	42	13	of	of	IN
cord-344382-vge4ho2v	42	14	angiotensin	angiotensin	NN
cord-344382-vge4ho2v	42	15	II	II	NNP
cord-344382-vge4ho2v	42	16	,	,	,
cord-344382-vge4ho2v	42	17	a	a	DT
cord-344382-vge4ho2v	42	18	potentially	potentially	RB
cord-344382-vge4ho2v	42	19	useful	useful	JJ
cord-344382-vge4ho2v	42	20	activity	activity	NN
cord-344382-vge4ho2v	42	21	in	in	IN
cord-344382-vge4ho2v	42	22	SARS	SARS	NNP
cord-344382-vge4ho2v	42	23	-	-	HYPH
cord-344382-vge4ho2v	42	24	CoV-2	CoV-2	NNP
cord-344382-vge4ho2v	42	25	infection	infection	NN
cord-344382-vge4ho2v	42	26	.	.	.
cord-344382-vge4ho2v	43	1	12	12	CD
cord-344382-vge4ho2v	43	2	 	 	_SP
cord-344382-vge4ho2v	43	3	Reduced	reduce	VBN
cord-344382-vge4ho2v	43	4	glutathione	glutathione	NN
cord-344382-vge4ho2v	43	5	(	(	-LRB-
cord-344382-vge4ho2v	43	6	GSH	GSH	NNP
cord-344382-vge4ho2v	43	7	)	)	-RRB-
cord-344382-vge4ho2v	43	8	is	be	VBZ
cord-344382-vge4ho2v	43	9	a	a	DT
cord-344382-vge4ho2v	43	10	major	major	JJ
cord-344382-vge4ho2v	43	11	defense	defense	NN
cord-344382-vge4ho2v	43	12	mechanism	mechanism	NN
cord-344382-vge4ho2v	43	13	of	of	IN
cord-344382-vge4ho2v	43	14	the	the	DT
cord-344382-vge4ho2v	43	15	human	human	JJ
cord-344382-vge4ho2v	43	16	body	body	NN
cord-344382-vge4ho2v	43	17	and	and	CC
cord-344382-vge4ho2v	43	18	all	all	DT
cord-344382-vge4ho2v	43	19	living	live	VBG
cord-344382-vge4ho2v	43	20	beings	being	NNS
cord-344382-vge4ho2v	43	21	.	.	.
cord-344382-vge4ho2v	44	1	However	however	RB
cord-344382-vge4ho2v	44	2	,	,	,
cord-344382-vge4ho2v	44	3	being	be	VBG
cord-344382-vge4ho2v	44	4	a	a	DT
cord-344382-vge4ho2v	44	5	tripeptide	tripeptide	NN
cord-344382-vge4ho2v	44	6	(	(	-LRB-
cord-344382-vge4ho2v	44	7	γ	γ	NN
cord-344382-vge4ho2v	44	8	-	-	HYPH
cord-344382-vge4ho2v	44	9	glutamylcysteinylglycine	glutamylcysteinylglycine	NNP
cord-344382-vge4ho2v	44	10	)	)	-RRB-
cord-344382-vge4ho2v	44	11	,	,	,
cord-344382-vge4ho2v	44	12	it	-PRON-	PRP
cord-344382-vge4ho2v	44	13	poorly	poorly	RB
cord-344382-vge4ho2v	44	14	penetrates	penetrate	VBZ
cord-344382-vge4ho2v	44	15	cells	cell	NNS
cord-344382-vge4ho2v	44	16	.	.	.
cord-344382-vge4ho2v	45	1	L	l	NN
cord-344382-vge4ho2v	45	2	-	-	HYPH
cord-344382-vge4ho2v	45	3	cysteine	cysteine	NN
cord-344382-vge4ho2v	45	4	(	(	-LRB-
cord-344382-vge4ho2v	45	5	L	L	NNP
cord-344382-vge4ho2v	45	6	-	-	HYPH
cord-344382-vge4ho2v	45	7	cys	cys	NNP
cord-344382-vge4ho2v	45	8	)	)	-RRB-
cord-344382-vge4ho2v	45	9	is	be	VBZ
cord-344382-vge4ho2v	45	10	the	the	DT
cord-344382-vge4ho2v	45	11	rate	rate	NN
cord-344382-vge4ho2v	45	12	-	-	HYPH
cord-344382-vge4ho2v	45	13	limiting	limit	VBG
cord-344382-vge4ho2v	45	14	amino	amino	NN
cord-344382-vge4ho2v	45	15	acid	acid	NN
cord-344382-vge4ho2v	45	16	in	in	IN
cord-344382-vge4ho2v	45	17	GSH	GSH	NNP
cord-344382-vge4ho2v	45	18	synthesis	synthesis	NN
cord-344382-vge4ho2v	45	19	.	.	.
cord-344382-vge4ho2v	46	1	NAC	NAC	NNP
cord-344382-vge4ho2v	46	2	easily	easily	RB
cord-344382-vge4ho2v	46	3	penetrates	penetrate	VBZ
cord-344382-vge4ho2v	46	4	cells	cell	NNS
cord-344382-vge4ho2v	46	5	where	where	WRB
cord-344382-vge4ho2v	46	6	it	-PRON-	PRP
cord-344382-vge4ho2v	46	7	is	be	VBZ
cord-344382-vge4ho2v	46	8	deacetylated	deacetylate	VBN
cord-344382-vge4ho2v	46	9	to	to	TO
cord-344382-vge4ho2v	46	10	yield	yield	VB
cord-344382-vge4ho2v	46	11	L	L	NNP
cord-344382-vge4ho2v	46	12	-	-	HYPH
cord-344382-vge4ho2v	46	13	cys	cys	NNP
cord-344382-vge4ho2v	46	14	thereby	thereby	RB
cord-344382-vge4ho2v	46	15	promoting	promote	VBG
cord-344382-vge4ho2v	46	16	GSH	GSH	NNP
cord-344382-vge4ho2v	46	17	synthesis	synthesis	NN
cord-344382-vge4ho2v	46	18	.	.	.
cord-344382-vge4ho2v	47	1	Therefore	therefore	RB
cord-344382-vge4ho2v	47	2	,	,	,
cord-344382-vge4ho2v	47	3	NAC	NAC	NNP
cord-344382-vge4ho2v	47	4	works	work	VBZ
cord-344382-vge4ho2v	47	5	per	per	FW
cord-344382-vge4ho2v	47	6	se	se	FW
cord-344382-vge4ho2v	47	7	in	in	IN
cord-344382-vge4ho2v	47	8	the	the	DT
cord-344382-vge4ho2v	47	9	extracellular	extracellular	JJ
cord-344382-vge4ho2v	47	10	environment	environment	NN
cord-344382-vge4ho2v	47	11	and	and	CC
cord-344382-vge4ho2v	47	12	as	as	IN
cord-344382-vge4ho2v	47	13	a	a	DT
cord-344382-vge4ho2v	47	14	precursor	precursor	NN
cord-344382-vge4ho2v	47	15	of	of	IN
cord-344382-vge4ho2v	47	16	GSH	GSH	NNP
cord-344382-vge4ho2v	47	17	inside	inside	IN
cord-344382-vge4ho2v	47	18	cells	cell	NNS
cord-344382-vge4ho2v	47	19	.	.	.
cord-344382-vge4ho2v	48	1	Accordingly	accordingly	RB
cord-344382-vge4ho2v	48	2	,	,	,
cord-344382-vge4ho2v	48	3	all	all	PDT
cord-344382-vge4ho2v	48	4	its	-PRON-	PRP$
cord-344382-vge4ho2v	48	5	intracellular	intracellular	JJ
cord-344382-vge4ho2v	48	6	effects	effect	NNS
cord-344382-vge4ho2v	48	7	are	be	VBP
cord-344382-vge4ho2v	48	8	mediated	mediate	VBN
cord-344382-vge4ho2v	48	9	by	by	IN
cord-344382-vge4ho2v	48	10	GSH	GSH	NNP
cord-344382-vge4ho2v	48	11	replenishment	replenishment	NN
cord-344382-vge4ho2v	48	12	.	.	.
cord-344382-vge4ho2v	49	1	Recycling	recycling	NN
cord-344382-vge4ho2v	49	2	of	of	IN
cord-344382-vge4ho2v	49	3	GSH	GSH	NNP
cord-344382-vge4ho2v	49	4	increases	increase	NNS
cord-344382-vge4ho2v	49	5	but	but	CC
cord-344382-vge4ho2v	49	6	can	can	MD
cord-344382-vge4ho2v	49	7	not	not	RB
cord-344382-vge4ho2v	49	8	match	match	VB
cord-344382-vge4ho2v	49	9	the	the	DT
cord-344382-vge4ho2v	49	10	high	high	JJ
cord-344382-vge4ho2v	49	11	consumption	consumption	NN
cord-344382-vge4ho2v	49	12	in	in	IN
cord-344382-vge4ho2v	49	13	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	49	14	lung	lung	NN
cord-344382-vge4ho2v	49	15	disease	disease	NN
cord-344382-vge4ho2v	49	16	.	.	.
cord-344382-vge4ho2v	50	1	This	this	DT
cord-344382-vge4ho2v	50	2	requires	require	VBZ
cord-344382-vge4ho2v	50	3	new	new	JJ
cord-344382-vge4ho2v	50	4	GSH	GSH	NNP
cord-344382-vge4ho2v	50	5	synthesis	synthesis	NN
cord-344382-vge4ho2v	50	6	,	,	,
cord-344382-vge4ho2v	50	7	which	which	WDT
cord-344382-vge4ho2v	50	8	increases	increase	VBZ
cord-344382-vge4ho2v	50	9	enormously	enormously	RB
cord-344382-vge4ho2v	50	10	,	,	,
cord-344382-vge4ho2v	50	11	largely	largely	RB
cord-344382-vge4ho2v	50	12	through	through	IN
cord-344382-vge4ho2v	50	13	activation	activation	NN
cord-344382-vge4ho2v	50	14	and	and	CC
cord-344382-vge4ho2v	50	15	up	up	RB
cord-344382-vge4ho2v	50	16	-	-	HYPH
cord-344382-vge4ho2v	50	17	regulated	regulate	VBN
cord-344382-vge4ho2v	50	18	production	production	NN
cord-344382-vge4ho2v	50	19	of	of	IN
cord-344382-vge4ho2v	50	20	glutamate	glutamate	NN
cord-344382-vge4ho2v	50	21	-	-	HYPH
cord-344382-vge4ho2v	50	22	cysteine	cysteine	NN
cord-344382-vge4ho2v	50	23	ligase	ligase	NN
cord-344382-vge4ho2v	50	24	(	(	-LRB-
cord-344382-vge4ho2v	50	25	GCL	GCL	NNP
cord-344382-vge4ho2v	50	26	)	)	-RRB-
cord-344382-vge4ho2v	50	27	,	,	,
cord-344382-vge4ho2v	50	28	the	the	DT
cord-344382-vge4ho2v	50	29	rate	rate	NN
cord-344382-vge4ho2v	50	30	-	-	HYPH
cord-344382-vge4ho2v	50	31	limiting	limit	VBG
cord-344382-vge4ho2v	50	32	enzyme	enzyme	NN
cord-344382-vge4ho2v	50	33	for	for	IN
cord-344382-vge4ho2v	50	34	GSH	GSH	NNP
cord-344382-vge4ho2v	50	35	biosynthesis	biosynthesis	NN
cord-344382-vge4ho2v	50	36	that	that	WDT
cord-344382-vge4ho2v	50	37	in	in	IN
cord-344382-vge4ho2v	50	38	turn	turn	NN
cord-344382-vge4ho2v	50	39	depends	depend	VBZ
cord-344382-vge4ho2v	50	40	on	on	IN
cord-344382-vge4ho2v	50	41	the	the	DT
cord-344382-vge4ho2v	50	42	availability	availability	NN
cord-344382-vge4ho2v	50	43	of	of	IN
cord-344382-vge4ho2v	50	44	intracellular	intracellular	JJ
cord-344382-vge4ho2v	50	45	L	L	NNP
cord-344382-vge4ho2v	50	46	-	-	HYPH
cord-344382-vge4ho2v	50	47	cys	cys	NNP
cord-344382-vge4ho2v	50	48	,	,	,
cord-344382-vge4ho2v	50	49	the	the	DT
cord-344382-vge4ho2v	50	50	rate	rate	NN
cord-344382-vge4ho2v	50	51	-	-	HYPH
cord-344382-vge4ho2v	50	52	limiting	limit	VBG
cord-344382-vge4ho2v	50	53	substrate	substrate	NN
cord-344382-vge4ho2v	50	54	for	for	IN
cord-344382-vge4ho2v	50	55	the	the	DT
cord-344382-vge4ho2v	50	56	enzyme	enzyme	NN
cord-344382-vge4ho2v	50	57	.	.	.
cord-344382-vge4ho2v	51	1	13	13	CD
cord-344382-vge4ho2v	51	2	NAC	NAC	NNP
cord-344382-vge4ho2v	51	3	has	have	VBZ
cord-344382-vge4ho2v	51	4	better	well	JJR
cord-344382-vge4ho2v	51	5	oral	oral	JJ
cord-344382-vge4ho2v	51	6	and	and	CC
cord-344382-vge4ho2v	51	7	topical	topical	JJ
cord-344382-vge4ho2v	51	8	bioavailability	bioavailability	NN
cord-344382-vge4ho2v	51	9	than	than	IN
cord-344382-vge4ho2v	51	10	GSH	GSH	NNP
cord-344382-vge4ho2v	51	11	,	,	,
cord-344382-vge4ho2v	51	12	and	and	CC
cord-344382-vge4ho2v	51	13	has	have	VBZ
cord-344382-vge4ho2v	51	14	an	an	DT
cord-344382-vge4ho2v	51	15	excellent	excellent	JJ
cord-344382-vge4ho2v	51	16	safety	safety	NN
cord-344382-vge4ho2v	51	17	profile	profile	NN
cord-344382-vge4ho2v	51	18	.	.	.
cord-344382-vge4ho2v	52	1	However	however	RB
cord-344382-vge4ho2v	52	2	,	,	,
cord-344382-vge4ho2v	52	3	the	the	DT
cord-344382-vge4ho2v	52	4	systemic	systemic	JJ
cord-344382-vge4ho2v	52	5	bioavailability	bioavailability	NN
cord-344382-vge4ho2v	52	6	of	of	IN
cord-344382-vge4ho2v	52	7	NAC	NAC	NNP
cord-344382-vge4ho2v	52	8	after	after	IN
cord-344382-vge4ho2v	52	9	oral	oral	JJ
cord-344382-vge4ho2v	52	10	administration	administration	NN
cord-344382-vge4ho2v	52	11	is	be	VBZ
cord-344382-vge4ho2v	52	12	relatively	relatively	RB
cord-344382-vge4ho2v	52	13	poor	poor	JJ
cord-344382-vge4ho2v	52	14	.	.	.
cord-344382-vge4ho2v	53	1	14	14	CD
cord-344382-vge4ho2v	54	1	This	this	DT
cord-344382-vge4ho2v	54	2	thiol	thiol	NN
cord-344382-vge4ho2v	54	3	has	have	VBZ
cord-344382-vge4ho2v	54	4	been	be	VBN
cord-344382-vge4ho2v	54	5	in	in	IN
cord-344382-vge4ho2v	54	6	clinical	clinical	JJ
cord-344382-vge4ho2v	54	7	use	use	NN
cord-344382-vge4ho2v	54	8	since	since	IN
cord-344382-vge4ho2v	54	9	the	the	DT
cord-344382-vge4ho2v	54	10	1960s	1960	NNS
cord-344382-vge4ho2v	54	11	as	as	IN
cord-344382-vge4ho2v	54	12	a	a	DT
cord-344382-vge4ho2v	54	13	mucolytic	mucolytic	JJ
cord-344382-vge4ho2v	54	14	agent	agent	NN
cord-344382-vge4ho2v	54	15	,	,	,
cord-344382-vge4ho2v	54	16	usually	usually	RB
cord-344382-vge4ho2v	54	17	at	at	IN
cord-344382-vge4ho2v	54	18	the	the	DT
cord-344382-vge4ho2v	54	19	oral	oral	JJ
cord-344382-vge4ho2v	54	20	dose	dose	NN
cord-344382-vge4ho2v	54	21	of	of	IN
cord-344382-vge4ho2v	54	22	600	600	CD
cord-344382-vge4ho2v	54	23	mg	mg	NN
cord-344382-vge4ho2v	54	24	,	,	,
cord-344382-vge4ho2v	54	25	due	due	IN
cord-344382-vge4ho2v	54	26	to	to	IN
cord-344382-vge4ho2v	54	27	its	-PRON-	PRP$
cord-344382-vge4ho2v	54	28	ability	ability	NN
cord-344382-vge4ho2v	54	29	to	to	TO
cord-344382-vge4ho2v	54	30	break	break	VB
cord-344382-vge4ho2v	54	31	the	the	DT
cord-344382-vge4ho2v	54	32	disulfide	disulfide	JJ
cord-344382-vge4ho2v	54	33	bonds	bond	NNS
cord-344382-vge4ho2v	54	34	of	of	IN
cord-344382-vge4ho2v	54	35	mucus	mucus	NN
cord-344382-vge4ho2v	54	36	and	and	CC
cord-344382-vge4ho2v	54	37	depolymerize	depolymerize	NN
cord-344382-vge4ho2v	54	38	mucin	mucin	NN
cord-344382-vge4ho2v	54	39	.	.	.
cord-344382-vge4ho2v	55	1	As	as	IN
cord-344382-vge4ho2v	55	2	previously	previously	RB
cord-344382-vge4ho2v	55	3	mentioned	mention	VBN
cord-344382-vge4ho2v	55	4	,	,	,
cord-344382-vge4ho2v	55	5	breaking	break	VBG
cord-344382-vge4ho2v	55	6	disulfide	disulfide	JJ
cord-344382-vge4ho2v	55	7	bonds	bond	NNS
cord-344382-vge4ho2v	55	8	into	into	IN
cord-344382-vge4ho2v	55	9	thiol	thiol	NN
cord-344382-vge4ho2v	55	10	groups	group	NNS
cord-344382-vge4ho2v	55	11	may	may	MD
cord-344382-vge4ho2v	55	12	also	also	RB
cord-344382-vge4ho2v	55	13	reduce	reduce	VB
cord-344382-vge4ho2v	55	14	the	the	DT
cord-344382-vge4ho2v	55	15	affinity	affinity	NN
cord-344382-vge4ho2v	55	16	for	for	IN
cord-344382-vge4ho2v	55	17	the	the	DT
cord-344382-vge4ho2v	55	18	virus	virus	NN
cord-344382-vge4ho2v	55	19	to	to	TO
cord-344382-vge4ho2v	55	20	attach	attach	VB
cord-344382-vge4ho2v	55	21	to	to	IN
cord-344382-vge4ho2v	55	22	ACE2	ACE2	NNP
cord-344382-vge4ho2v	55	23	sites	site	NNS
cord-344382-vge4ho2v	55	24	.	.	.
cord-344382-vge4ho2v	56	1	9	9	CD
cord-344382-vge4ho2v	56	2	NAC	NAC	NNP
cord-344382-vge4ho2v	56	3	is	be	VBZ
cord-344382-vge4ho2v	56	4	also	also	RB
cord-344382-vge4ho2v	56	5	used	use	VBN
cord-344382-vge4ho2v	56	6	in	in	IN
cord-344382-vge4ho2v	56	7	nebulized	nebulize	VBN
cord-344382-vge4ho2v	56	8	format	format	NN
cord-344382-vge4ho2v	56	9	in	in	IN
cord-344382-vge4ho2v	56	10	patients	patient	NNS
cord-344382-vge4ho2v	56	11	with	with	IN
cord-344382-vge4ho2v	56	12	acute	acute	JJ
cord-344382-vge4ho2v	56	13	bronchopulmonary	bronchopulmonary	JJ
cord-344382-vge4ho2v	56	14	disease	disease	NN
cord-344382-vge4ho2v	56	15	,	,	,
cord-344382-vge4ho2v	56	16	such	such	JJ
cord-344382-vge4ho2v	56	17	as	as	IN
cord-344382-vge4ho2v	56	18	pneumonia	pneumonia	NN
cord-344382-vge4ho2v	56	19	,	,	,
cord-344382-vge4ho2v	56	20	bronchitis	bronchitis	NN
cord-344382-vge4ho2v	56	21	,	,	,
cord-344382-vge4ho2v	56	22	and	and	CC
cord-344382-vge4ho2v	56	23	tracheobronchitis	tracheobronchitis	NN
cord-344382-vge4ho2v	56	24	.	.	.
cord-344382-vge4ho2v	57	1	Moreover	moreover	RB
cord-344382-vge4ho2v	57	2	,	,	,
cord-344382-vge4ho2v	57	3	NAC	NAC	NNP
cord-344382-vge4ho2v	57	4	is	be	VBZ
cord-344382-vge4ho2v	57	5	quoted	quote	VBN
cord-344382-vge4ho2v	57	6	in	in	IN
cord-344382-vge4ho2v	57	7	the	the	DT
cord-344382-vge4ho2v	57	8	WHO	WHO	NNP
cord-344382-vge4ho2v	57	9	Model	Model	NNP
cord-344382-vge4ho2v	57	10	List	List	NNP
cord-344382-vge4ho2v	57	11	of	of	IN
cord-344382-vge4ho2v	57	12	Essential	Essential	NNP
cord-344382-vge4ho2v	57	13	Medicines	Medicines	NNPS
cord-344382-vge4ho2v	57	14	as	as	IN
cord-344382-vge4ho2v	57	15	an	an	DT
cord-344382-vge4ho2v	57	16	antidote	antidote	NN
cord-344382-vge4ho2v	57	17	in	in	IN
cord-344382-vge4ho2v	57	18	poisonings	poisoning	NNS
cord-344382-vge4ho2v	57	19	.	.	.
cord-344382-vge4ho2v	58	1	At	at	IN
cord-344382-vge4ho2v	58	2	doses	dose	NNS
cord-344382-vge4ho2v	58	3	as	as	RB
cord-344382-vge4ho2v	58	4	high	high	JJ
cord-344382-vge4ho2v	58	5	as	as	IN
cord-344382-vge4ho2v	58	6	150	150	CD
cord-344382-vge4ho2v	58	7	mg	mg	NNP
cord-344382-vge4ho2v	58	8	/	/	SYM
cord-344382-vge4ho2v	58	9	kg	kg	NNP
cord-344382-vge4ho2v	58	10	intravenously	intravenously	RB
cord-344382-vge4ho2v	58	11	,	,	,
cord-344382-vge4ho2v	58	12	NAC	NAC	NNP
cord-344382-vge4ho2v	58	13	is	be	VBZ
cord-344382-vge4ho2v	58	14	extensively	extensively	RB
cord-344382-vge4ho2v	58	15	used	use	VBN
cord-344382-vge4ho2v	58	16	and	and	CC
cord-344382-vge4ho2v	58	17	is	be	VBZ
cord-344382-vge4ho2v	58	18	in	in	IN
cord-344382-vge4ho2v	58	19	standard	standard	JJ
cord-344382-vge4ho2v	58	20	practice	practice	NN
cord-344382-vge4ho2v	58	21	as	as	IN
cord-344382-vge4ho2v	58	22	a	a	DT
cord-344382-vge4ho2v	58	23	clinically	clinically	RB
cord-344382-vge4ho2v	58	24	approved	approve	VBN
cord-344382-vge4ho2v	58	25	antidote	antidote	NN
cord-344382-vge4ho2v	58	26	against	against	IN
cord-344382-vge4ho2v	58	27	paracetamol	paracetamol	NNP
cord-344382-vge4ho2v	58	28	(	(	-LRB-
cord-344382-vge4ho2v	58	29	acetaminophen	acetaminophen	NN
cord-344382-vge4ho2v	58	30	)	)	-RRB-
cord-344382-vge4ho2v	58	31	intoxication	intoxication	NN
cord-344382-vge4ho2v	58	32	,	,	,
cord-344382-vge4ho2v	58	33	and	and	CC
cord-344382-vge4ho2v	58	34	it	-PRON-	PRP
cord-344382-vge4ho2v	58	35	is	be	VBZ
cord-344382-vge4ho2v	58	36	almost	almost	RB
cord-344382-vge4ho2v	58	37	100	100	CD
cord-344382-vge4ho2v	58	38	%	%	NN
cord-344382-vge4ho2v	58	39	effective	effective	JJ
cord-344382-vge4ho2v	58	40	if	if	IN
cord-344382-vge4ho2v	58	41	given	give	VBN
cord-344382-vge4ho2v	58	42	within	within	IN
cord-344382-vge4ho2v	58	43	8	8	CD
cord-344382-vge4ho2v	58	44	hours	hour	NNS
cord-344382-vge4ho2v	58	45	postingestion	postingestion	NN
cord-344382-vge4ho2v	58	46	.	.	.
cord-344382-vge4ho2v	59	1	15	15	CD
cord-344382-vge4ho2v	60	1	Paracetamol	paracetamol	JJ
cord-344382-vge4ho2v	60	2	overdosage	overdosage	NN
cord-344382-vge4ho2v	60	3	may	may	MD
cord-344382-vge4ho2v	60	4	cause	cause	VB
cord-344382-vge4ho2v	60	5	mitochondrial	mitochondrial	JJ
cord-344382-vge4ho2v	60	6	oxidative	oxidative	JJ
cord-344382-vge4ho2v	60	7	imbalance	imbalance	NN
cord-344382-vge4ho2v	60	8	and	and	CC
cord-344382-vge4ho2v	60	9	nitrosative	nitrosative	JJ
cord-344382-vge4ho2v	60	10	stress	stress	NN
cord-344382-vge4ho2v	60	11	leading	lead	VBG
cord-344382-vge4ho2v	60	12	to	to	IN
cord-344382-vge4ho2v	60	13	liver	liver	NN
cord-344382-vge4ho2v	60	14	injury	injury	NN
cord-344382-vge4ho2v	60	15	,	,	,
cord-344382-vge4ho2v	60	16	which	which	WDT
cord-344382-vge4ho2v	60	17	is	be	VBZ
cord-344382-vge4ho2v	60	18	the	the	DT
cord-344382-vge4ho2v	60	19	most	most	RBS
cord-344382-vge4ho2v	60	20	common	common	JJ
cord-344382-vge4ho2v	60	21	cause	cause	NN
cord-344382-vge4ho2v	60	22	of	of	IN
cord-344382-vge4ho2v	60	23	acute	acute	JJ
cord-344382-vge4ho2v	60	24	liver	liver	NN
cord-344382-vge4ho2v	60	25	failure	failure	NN
cord-344382-vge4ho2v	60	26	in	in	IN
cord-344382-vge4ho2v	60	27	many	many	JJ
cord-344382-vge4ho2v	60	28	countries	country	NNS
cord-344382-vge4ho2v	60	29	.	.	.
cord-344382-vge4ho2v	61	1	16	16	CD
cord-344382-vge4ho2v	62	1	The	the	DT
cord-344382-vge4ho2v	62	2	intravenous	intravenous	JJ
cord-344382-vge4ho2v	62	3	administration	administration	NN
cord-344382-vge4ho2v	62	4	of	of	IN
cord-344382-vge4ho2v	62	5	NAC	NAC	NNP
cord-344382-vge4ho2v	62	6	is	be	VBZ
cord-344382-vge4ho2v	62	7	also	also	RB
cord-344382-vge4ho2v	62	8	used	use	VBN
cord-344382-vge4ho2v	62	9	to	to	TO
cord-344382-vge4ho2v	62	10	prevent	prevent	VB
cord-344382-vge4ho2v	62	11	contrast	contrast	NN
cord-344382-vge4ho2v	62	12	-	-	HYPH
cord-344382-vge4ho2v	62	13	induced	induce	VBN
cord-344382-vge4ho2v	62	14	nephropathy	nephropathy	NN
cord-344382-vge4ho2v	62	15	that	that	IN
cord-344382-vge4ho2v	62	16	,	,	,
cord-344382-vge4ho2v	62	17	again	again	RB
cord-344382-vge4ho2v	62	18	,	,	,
cord-344382-vge4ho2v	62	19	is	be	VBZ
cord-344382-vge4ho2v	62	20	an	an	DT
cord-344382-vge4ho2v	62	21	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	62	22	condition	condition	NN
cord-344382-vge4ho2v	62	23	.	.	.
cord-344382-vge4ho2v	63	1	15	15	CD
cord-344382-vge4ho2v	64	1	In	in	IN
cord-344382-vge4ho2v	64	2	addition	addition	NN
cord-344382-vge4ho2v	64	3	,	,	,
cord-344382-vge4ho2v	64	4	this	this	DT
cord-344382-vge4ho2v	64	5	pleiotropic	pleiotropic	JJ
cord-344382-vge4ho2v	64	6	drug	drug	NN
cord-344382-vge4ho2v	64	7	has	have	VBZ
cord-344382-vge4ho2v	64	8	been	be	VBN
cord-344382-vge4ho2v	64	9	proposed	propose	VBN
cord-344382-vge4ho2v	64	10	to	to	TO
cord-344382-vge4ho2v	64	11	attenuate	attenuate	VB
cord-344382-vge4ho2v	64	12	the	the	DT
cord-344382-vge4ho2v	64	13	toxicity	toxicity	NN
cord-344382-vge4ho2v	64	14	of	of	IN
cord-344382-vge4ho2v	64	15	various	various	JJ
cord-344382-vge4ho2v	64	16	agents	agent	NNS
cord-344382-vge4ho2v	64	17	that	that	WDT
cord-344382-vge4ho2v	64	18	cause	cause	VBP
cord-344382-vge4ho2v	64	19	the	the	DT
cord-344382-vge4ho2v	64	20	generation	generation	NN
cord-344382-vge4ho2v	64	21	of	of	IN
cord-344382-vge4ho2v	64	22	free	free	JJ
cord-344382-vge4ho2v	64	23	radicals	radical	NNS
cord-344382-vge4ho2v	64	24	as	as	RB
cord-344382-vge4ho2v	64	25	well	well	RB
cord-344382-vge4ho2v	64	26	as	as	IN
cord-344382-vge4ho2v	64	27	for	for	IN
cord-344382-vge4ho2v	64	28	the	the	DT
cord-344382-vge4ho2v	64	29	therapy	therapy	NN
cord-344382-vge4ho2v	64	30	and/or	and/or	CC
cord-344382-vge4ho2v	64	31	prevention	prevention	NN
cord-344382-vge4ho2v	64	32	of	of	IN
cord-344382-vge4ho2v	64	33	a	a	DT
cord-344382-vge4ho2v	64	34	variety	variety	NN
cord-344382-vge4ho2v	64	35	of	of	IN
cord-344382-vge4ho2v	64	36	diseases	disease	NNS
cord-344382-vge4ho2v	64	37	involving	involve	VBG
cord-344382-vge4ho2v	64	38	GSH	GSH	NNP
cord-344382-vge4ho2v	64	39	depletion	depletion	NN
cord-344382-vge4ho2v	64	40	and	and	CC
cord-344382-vge4ho2v	64	41	redox	redox	NN
cord-344382-vge4ho2v	64	42	status	status	NN
cord-344382-vge4ho2v	64	43	alterations	alteration	NNS
cord-344382-vge4ho2v	64	44	,	,	,
cord-344382-vge4ho2v	64	45	such	such	JJ
cord-344382-vge4ho2v	64	46	as	as	IN
cord-344382-vge4ho2v	64	47	heart	heart	NN
cord-344382-vge4ho2v	64	48	diseases	disease	NNS
cord-344382-vge4ho2v	64	49	,	,	,
cord-344382-vge4ho2v	64	50	diabetes	diabetes	NN
cord-344382-vge4ho2v	64	51	,	,	,
cord-344382-vge4ho2v	64	52	AIDS	AIDS	NNP
cord-344382-vge4ho2v	64	53	,	,	,
cord-344382-vge4ho2v	64	54	neurodegenerative	neurodegenerative	JJ
cord-344382-vge4ho2v	64	55	diseases	disease	NNS
cord-344382-vge4ho2v	64	56	,	,	,
cord-344382-vge4ho2v	64	57	neuropsychiatric	neuropsychiatric	JJ
cord-344382-vge4ho2v	64	58	disorders	disorder	NNS
cord-344382-vge4ho2v	64	59	,	,	,
cord-344382-vge4ho2v	64	60	and	and	CC
cord-344382-vge4ho2v	64	61	several	several	JJ
cord-344382-vge4ho2v	64	62	other	other	JJ
cord-344382-vge4ho2v	64	63	conditions	condition	NNS
cord-344382-vge4ho2v	64	64	.	.	.
cord-344382-vge4ho2v	65	1	14,17	14,17	CD
cord-344382-vge4ho2v	65	2	Oxidative	oxidative	JJ
cord-344382-vge4ho2v	65	3	stress	stress	NN
cord-344382-vge4ho2v	65	4	and	and	CC
cord-344382-vge4ho2v	65	5	inflammation	inflammation	NN
cord-344382-vge4ho2v	65	6	are	be	VBP
cord-344382-vge4ho2v	65	7	strictly	strictly	RB
cord-344382-vge4ho2v	65	8	inter	inter	JJ
cord-344382-vge4ho2v	65	9	-	-	JJ
cord-344382-vge4ho2v	65	10	related	related	JJ
cord-344382-vge4ho2v	65	11	.	.	.
cord-344382-vge4ho2v	66	1	Exposure	exposure	NN
cord-344382-vge4ho2v	66	2	of	of	IN
cord-344382-vge4ho2v	66	3	cells	cell	NNS
cord-344382-vge4ho2v	66	4	either	either	CC
cord-344382-vge4ho2v	66	5	to	to	IN
cord-344382-vge4ho2v	66	6	the	the	DT
cord-344382-vge4ho2v	66	7	hydroxyl	hydroxyl	NN
cord-344382-vge4ho2v	66	8	radical	radical	JJ
cord-344382-vge4ho2v	66	9	(	(	-LRB-
cord-344382-vge4ho2v	66	10	•OH	•OH	NNP
cord-344382-vge4ho2v	66	11	)	)	-RRB-
cord-344382-vge4ho2v	66	12	or	or	CC
cord-344382-vge4ho2v	66	13	the	the	DT
cord-344382-vge4ho2v	66	14	superoxide	superoxide	NN
cord-344382-vge4ho2v	66	15	radical	radical	JJ
cord-344382-vge4ho2v	66	16	anion	anion	NN
cord-344382-vge4ho2v	66	17	(	(	-LRB-
cord-344382-vge4ho2v	66	18	O	o	UH
cord-344382-vge4ho2v	66	19	2	2	CD
cord-344382-vge4ho2v	66	20	•	•	NN
cord-344382-vge4ho2v	66	21	−	−	CD
cord-344382-vge4ho2v	66	22	)	)	-RRB-
cord-344382-vge4ho2v	66	23	induces	induce	VBZ
cord-344382-vge4ho2v	66	24	a	a	DT
cord-344382-vge4ho2v	66	25	dose	dose	NN
cord-344382-vge4ho2v	66	26	-	-	HYPH
cord-344382-vge4ho2v	66	27	dependent	dependent	JJ
cord-344382-vge4ho2v	66	28	release	release	NN
cord-344382-vge4ho2v	66	29	of	of	IN
cord-344382-vge4ho2v	66	30	pro	pro	JJ
cord-344382-vge4ho2v	66	31	-	-	JJ
cord-344382-vge4ho2v	66	32	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	66	33	cytokines	cytokine	NNS
cord-344382-vge4ho2v	66	34	.	.	.
cord-344382-vge4ho2v	67	1	Lipopolysaccharide	Lipopolysaccharide	NNP
cord-344382-vge4ho2v	67	2	(	(	-LRB-
cord-344382-vge4ho2v	67	3	LPS	LPS	NNP
cord-344382-vge4ho2v	67	4	)	)	-RRB-
cord-344382-vge4ho2v	67	5	induces	induce	VBZ
cord-344382-vge4ho2v	67	6	intracellular	intracellular	JJ
cord-344382-vge4ho2v	67	7	accumulation	accumulation	NN
cord-344382-vge4ho2v	67	8	of	of	IN
cord-344382-vge4ho2v	67	9	reactive	reactive	JJ
cord-344382-vge4ho2v	67	10	oxygen	oxygen	NN
cord-344382-vge4ho2v	67	11	species	specie	NNS
cord-344382-vge4ho2v	67	12	(	(	-LRB-
cord-344382-vge4ho2v	67	13	ROS	ROS	NNP
cord-344382-vge4ho2v	67	14	)	)	-RRB-
cord-344382-vge4ho2v	67	15	and	and	CC
cord-344382-vge4ho2v	67	16	augments	augment	VBZ
cord-344382-vge4ho2v	67	17	the	the	DT
cord-344382-vge4ho2v	67	18	release	release	NN
cord-344382-vge4ho2v	67	19	of	of	IN
cord-344382-vge4ho2v	67	20	interleukin	interleukin	NN
cord-344382-vge4ho2v	67	21	(	(	-LRB-
cord-344382-vge4ho2v	67	22	IL)-1beta	il)-1beta	NN
cord-344382-vge4ho2v	67	23	,	,	,
cord-344382-vge4ho2v	67	24	IL-6	IL-6	NNP
cord-344382-vge4ho2v	67	25	,	,	,
cord-344382-vge4ho2v	67	26	and	and	CC
cord-344382-vge4ho2v	67	27	tumor	tumor	NN
cord-344382-vge4ho2v	67	28	necrosis	necrosis	NN
cord-344382-vge4ho2v	67	29	factor	factor	NN
cord-344382-vge4ho2v	67	30	-	-	HYPH
cord-344382-vge4ho2v	67	31	alpha	alpha	NN
cord-344382-vge4ho2v	67	32	(	(	-LRB-
cord-344382-vge4ho2v	67	33	TNF	TNF	NNP
cord-344382-vge4ho2v	67	34	-	-	HYPH
cord-344382-vge4ho2v	67	35	α	α	NNP
cord-344382-vge4ho2v	67	36	)	)	-RRB-
cord-344382-vge4ho2v	67	37	.	.	.
cord-344382-vge4ho2v	68	1	A	a	DT
cord-344382-vge4ho2v	68	2	kappa	kappa	NN
cord-344382-vge4ho2v	68	3	B	b	NN
cord-344382-vge4ho2v	68	4	(	(	-LRB-
cord-344382-vge4ho2v	68	5	κB	κB	NNP
cord-344382-vge4ho2v	68	6	-	-	HYPH
cord-344382-vge4ho2v	68	7	α)/nuclear	α)/nuclear	JJ
cord-344382-vge4ho2v	68	8	factor	factor	NN
cord-344382-vge4ho2v	68	9	kappa	kappa	NN
cord-344382-vge4ho2v	68	10	B	B	NNP
cord-344382-vge4ho2v	68	11	(	(	-LRB-
cord-344382-vge4ho2v	68	12	NF	nf	NN
cord-344382-vge4ho2v	68	13	-	-	HYPH
cord-344382-vge4ho2v	68	14	κB)-independent	κb)-independent	NN
cord-344382-vge4ho2v	68	15	pathway	pathway	NN
cord-344382-vge4ho2v	68	16	mediates	mediate	VBZ
cord-344382-vge4ho2v	68	17	the	the	DT
cord-344382-vge4ho2v	68	18	redox	redox	NN
cord-344382-vge4ho2v	68	19	-	-	HYPH
cord-344382-vge4ho2v	68	20	dependent	dependent	JJ
cord-344382-vge4ho2v	68	21	regulation	regulation	NN
cord-344382-vge4ho2v	68	22	of	of	IN
cord-344382-vge4ho2v	68	23	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	68	24	cytokines	cytokine	NNS
cord-344382-vge4ho2v	68	25	,	,	,
cord-344382-vge4ho2v	68	26	and	and	CC
cord-344382-vge4ho2v	68	27	this	this	DT
cord-344382-vge4ho2v	68	28	process	process	NN
cord-344382-vge4ho2v	68	29	is	be	VBZ
cord-344382-vge4ho2v	68	30	enhanced	enhance	VBN
cord-344382-vge4ho2v	68	31	by	by	IN
cord-344382-vge4ho2v	68	32	GSH	GSH	NNP
cord-344382-vge4ho2v	68	33	depletion	depletion	NN
cord-344382-vge4ho2v	68	34	.	.	.
cord-344382-vge4ho2v	69	1	18	18	CD
cord-344382-vge4ho2v	69	2	Sadowska	Sadowska	NNP
cord-344382-vge4ho2v	69	3	,	,	,
cord-344382-vge4ho2v	69	4	2012	2012	CD
cord-344382-vge4ho2v	69	5	14	14	CD
cord-344382-vge4ho2v	69	6	)	)	-RRB-
cord-344382-vge4ho2v	69	7	.	.	.
cord-344382-vge4ho2v	70	1	The	the	DT
cord-344382-vge4ho2v	70	2	blue	blue	JJ
cord-344382-vge4ho2v	70	3	arrows	arrow	NNS
cord-344382-vge4ho2v	70	4	indicate	indicate	VBP
cord-344382-vge4ho2v	70	5	stimulation	stimulation	NN
cord-344382-vge4ho2v	70	6	of	of	IN
cord-344382-vge4ho2v	70	7	downstream	downstream	JJ
cord-344382-vge4ho2v	70	8	activities	activity	NNS
cord-344382-vge4ho2v	70	9	or	or	CC
cord-344382-vge4ho2v	70	10	pathways	pathway	NNS
cord-344382-vge4ho2v	70	11	,	,	,
cord-344382-vge4ho2v	70	12	whereas	whereas	IN
cord-344382-vge4ho2v	70	13	the	the	DT
cord-344382-vge4ho2v	70	14	T	t	NN
cord-344382-vge4ho2v	70	15	-	-	HYPH
cord-344382-vge4ho2v	70	16	shaped	shape	VBN
cord-344382-vge4ho2v	70	17	symbols	symbol	NNS
cord-344382-vge4ho2v	70	18	indicate	indicate	VBP
cord-344382-vge4ho2v	70	19	inhibition	inhibition	NN
cord-344382-vge4ho2v	70	20	of	of	IN
cord-344382-vge4ho2v	70	21	downstream	downstream	JJ
cord-344382-vge4ho2v	70	22	activities	activity	NNS
cord-344382-vge4ho2v	70	23	or	or	CC
cord-344382-vge4ho2v	70	24	pathways	pathway	NNS
cord-344382-vge4ho2v	70	25	.	.	.
cord-344382-vge4ho2v	71	1	See	see	VB
cord-344382-vge4ho2v	71	2	Text	Text	NNP
cord-344382-vge4ho2v	71	3	for	for	IN
cord-344382-vge4ho2v	71	4	details	detail	NNS
cord-344382-vge4ho2v	71	5	,	,	,
cord-344382-vge4ho2v	71	6	references	reference	NNS
cord-344382-vge4ho2v	71	7	,	,	,
cord-344382-vge4ho2v	71	8	and	and	CC
cord-344382-vge4ho2v	71	9	meaning	meaning	NN
cord-344382-vge4ho2v	71	10	of	of	IN
cord-344382-vge4ho2v	71	11	acronyms	acronym	NNS
cord-344382-vge4ho2v	71	12	ROS	ROS	NNP
cord-344382-vge4ho2v	71	13	and	and	CC
cord-344382-vge4ho2v	71	14	thiol	thiol	NN
cord-344382-vge4ho2v	71	15	antioxidants	antioxidant	NNS
cord-344382-vge4ho2v	71	16	,	,	,
cord-344382-vge4ho2v	71	17	including	include	VBG
cord-344382-vge4ho2v	71	18	GSH	GSH	NNP
cord-344382-vge4ho2v	71	19	,	,	,
cord-344382-vge4ho2v	71	20	regulate	regulate	VB
cord-344382-vge4ho2v	71	21	innate	innate	JJ
cord-344382-vge4ho2v	71	22	immunity	immunity	NN
cord-344382-vge4ho2v	71	23	at	at	IN
cord-344382-vge4ho2v	71	24	various	various	JJ
cord-344382-vge4ho2v	71	25	levels	level	NNS
cord-344382-vge4ho2v	71	26	,	,	,
cord-344382-vge4ho2v	71	27	as	as	IN
cord-344382-vge4ho2v	71	28	documented	document	VBN
cord-344382-vge4ho2v	71	29	by	by	IN
cord-344382-vge4ho2v	71	30	a	a	DT
cord-344382-vge4ho2v	71	31	broad	broad	JJ
cord-344382-vge4ho2v	71	32	literature	literature	NN
cord-344382-vge4ho2v	71	33	.	.	.
cord-344382-vge4ho2v	72	1	GSH	GSH	NNP
cord-344382-vge4ho2v	72	2	is	be	VBZ
cord-344382-vge4ho2v	72	3	not	not	RB
cord-344382-vge4ho2v	72	4	only	only	RB
cord-344382-vge4ho2v	72	5	important	important	JJ
cord-344382-vge4ho2v	72	6	as	as	IN
cord-344382-vge4ho2v	72	7	an	an	DT
cord-344382-vge4ho2v	72	8	antioxidant	antioxidant	NN
cord-344382-vge4ho2v	72	9	,	,	,
cord-344382-vge4ho2v	72	10	but	but	CC
cord-344382-vge4ho2v	72	11	also	also	RB
cord-344382-vge4ho2v	72	12	as	as	IN
cord-344382-vge4ho2v	72	13	a	a	DT
cord-344382-vge4ho2v	72	14	signaling	signal	VBG
cord-344382-vge4ho2v	72	15	molecule	molecule	NN
cord-344382-vge4ho2v	72	16	in	in	IN
cord-344382-vge4ho2v	72	17	the	the	DT
cord-344382-vge4ho2v	72	18	redox	redox	NN
cord-344382-vge4ho2v	72	19	-	-	HYPH
cord-344382-vge4ho2v	72	20	sensitive	sensitive	JJ
cord-344382-vge4ho2v	72	21	steps	step	NNS
cord-344382-vge4ho2v	72	22	of	of	IN
cord-344382-vge4ho2v	72	23	the	the	DT
cord-344382-vge4ho2v	72	24	cellular	cellular	JJ
cord-344382-vge4ho2v	72	25	mechanisms	mechanism	NNS
cord-344382-vge4ho2v	72	26	implicated	implicate	VBN
cord-344382-vge4ho2v	72	27	in	in	IN
cord-344382-vge4ho2v	72	28	inflammation	inflammation	NN
cord-344382-vge4ho2v	72	29	and	and	CC
cord-344382-vge4ho2v	72	30	host	host	NN
cord-344382-vge4ho2v	72	31	defense	defense	NN
cord-344382-vge4ho2v	72	32	against	against	IN
cord-344382-vge4ho2v	72	33	infection	infection	NN
cord-344382-vge4ho2v	72	34	.	.	.
cord-344382-vge4ho2v	73	1	19	19	CD
cord-344382-vge4ho2v	74	1	It	-PRON-	PRP
cord-344382-vge4ho2v	74	2	is	be	VBZ
cord-344382-vge4ho2v	74	3	noteworthy	noteworthy	JJ
cord-344382-vge4ho2v	74	4	that	that	IN
cord-344382-vge4ho2v	74	5	GSH	GSH	NNP
cord-344382-vge4ho2v	74	6	not	not	RB
cord-344382-vge4ho2v	74	7	only	only	RB
cord-344382-vge4ho2v	74	8	affects	affect	VBZ
cord-344382-vge4ho2v	74	9	certain	certain	JJ
cord-344382-vge4ho2v	74	10	factors	factor	NNS
cord-344382-vge4ho2v	74	11	involved	involve	VBN
cord-344382-vge4ho2v	74	12	in	in	IN
cord-344382-vge4ho2v	74	13	immunological	immunological	JJ
cord-344382-vge4ho2v	74	14	processes	process	NNS
cord-344382-vge4ho2v	74	15	,	,	,
cord-344382-vge4ho2v	74	16	but	but	CC
cord-344382-vge4ho2v	74	17	it	-PRON-	PRP
cord-344382-vge4ho2v	74	18	also	also	RB
cord-344382-vge4ho2v	74	19	modifies	modify	VBZ
cord-344382-vge4ho2v	74	20	complex	complex	JJ
cord-344382-vge4ho2v	74	21	immune	immune	JJ
cord-344382-vge4ho2v	74	22	reactions	reaction	NNS
cord-344382-vge4ho2v	74	23	such	such	JJ
cord-344382-vge4ho2v	74	24	as	as	IN
cord-344382-vge4ho2v	74	25	fever	fever	NN
cord-344382-vge4ho2v	74	26	,	,	,
cord-344382-vge4ho2v	74	27	and	and	CC
cord-344382-vge4ho2v	74	28	there	there	EX
cord-344382-vge4ho2v	74	29	are	be	VBP
cord-344382-vge4ho2v	74	30	data	datum	NNS
cord-344382-vge4ho2v	74	31	suggesting	suggest	VBG
cord-344382-vge4ho2v	74	32	that	that	IN
cord-344382-vge4ho2v	74	33	fever	fever	NN
cord-344382-vge4ho2v	74	34	induction	induction	NN
cord-344382-vge4ho2v	74	35	is	be	VBZ
cord-344382-vge4ho2v	74	36	associated	associate	VBN
cord-344382-vge4ho2v	74	37	with	with	IN
cord-344382-vge4ho2v	74	38	oxidative	oxidative	JJ
cord-344382-vge4ho2v	74	39	stress	stress	NN
cord-344382-vge4ho2v	74	40	.	.	.
cord-344382-vge4ho2v	75	1	20	20	CD
cord-344382-vge4ho2v	76	1	Although	although	IN
cord-344382-vge4ho2v	76	2	the	the	DT
cord-344382-vge4ho2v	76	3	complement	complement	NN
cord-344382-vge4ho2v	76	4	system	system	NN
cord-344382-vge4ho2v	76	5	is	be	VBZ
cord-344382-vge4ho2v	76	6	a	a	DT
cord-344382-vge4ho2v	76	7	key	key	JJ
cord-344382-vge4ho2v	76	8	mediator	mediator	NN
cord-344382-vge4ho2v	76	9	of	of	IN
cord-344382-vge4ho2v	76	10	the	the	DT
cord-344382-vge4ho2v	76	11	innate	innate	JJ
cord-344382-vge4ho2v	76	12	immune	immune	JJ
cord-344382-vge4ho2v	76	13	response	response	NN
cord-344382-vge4ho2v	76	14	that	that	WDT
cord-344382-vge4ho2v	76	15	protects	protect	VBZ
cord-344382-vge4ho2v	76	16	against	against	IN
cord-344382-vge4ho2v	76	17	infectious	infectious	JJ
cord-344382-vge4ho2v	76	18	agents	agent	NNS
cord-344382-vge4ho2v	76	19	,	,	,
cord-344382-vge4ho2v	76	20	it	-PRON-	PRP
cord-344382-vge4ho2v	76	21	also	also	RB
cord-344382-vge4ho2v	76	22	plays	play	VBZ
cord-344382-vge4ho2v	76	23	a	a	DT
cord-344382-vge4ho2v	76	24	critical	critical	JJ
cord-344382-vge4ho2v	76	25	role	role	NN
cord-344382-vge4ho2v	76	26	in	in	IN
cord-344382-vge4ho2v	76	27	promoting	promote	VBG
cord-344382-vge4ho2v	76	28	the	the	DT
cord-344382-vge4ho2v	76	29	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	76	30	process	process	NN
cord-344382-vge4ho2v	76	31	that	that	WDT
cord-344382-vge4ho2v	76	32	leads	lead	VBZ
cord-344382-vge4ho2v	76	33	to	to	IN
cord-344382-vge4ho2v	76	34	tissue	tissue	NN
cord-344382-vge4ho2v	76	35	injury	injury	NN
cord-344382-vge4ho2v	76	36	.	.	.
cord-344382-vge4ho2v	77	1	21	21	CD
cord-344382-vge4ho2v	78	1	In	in	IN
cord-344382-vge4ho2v	78	2	particular	particular	JJ
cord-344382-vge4ho2v	78	3	,	,	,
cord-344382-vge4ho2v	78	4	complement	complement	NN
cord-344382-vge4ho2v	78	5	may	may	MD
cord-344382-vge4ho2v	78	6	be	be	VB
cord-344382-vge4ho2v	78	7	involved	involve	VBN
cord-344382-vge4ho2v	78	8	in	in	IN
cord-344382-vge4ho2v	78	9	coronavirus	coronavirus	NN
cord-344382-vge4ho2v	78	10	pathogenesis	pathogenesis	NN
cord-344382-vge4ho2v	78	11	,	,	,
cord-344382-vge4ho2v	78	12	as	as	IN
cord-344382-vge4ho2v	78	13	inferred	infer	VBN
cord-344382-vge4ho2v	78	14	from	from	IN
cord-344382-vge4ho2v	78	15	the	the	DT
cord-344382-vge4ho2v	78	16	finding	finding	NN
cord-344382-vge4ho2v	78	17	that	that	IN
cord-344382-vge4ho2v	78	18	C3	c3	NN
cord-344382-vge4ho2v	78	19	knockout	knockout	NN
cord-344382-vge4ho2v	78	20	mice	mouse	NNS
cord-344382-vge4ho2v	78	21	infected	infect	VBN
cord-344382-vge4ho2v	78	22	with	with	IN
cord-344382-vge4ho2v	78	23	SARS	SARS	NNP
cord-344382-vge4ho2v	78	24	-	-	HYPH
cord-344382-vge4ho2v	78	25	CoV	CoV	NNP
cord-344382-vge4ho2v	78	26	have	have	VBP
cord-344382-vge4ho2v	78	27	less	less	JJR
cord-344382-vge4ho2v	78	28	lung	lung	NN
cord-344382-vge4ho2v	78	29	disease	disease	NN
cord-344382-vge4ho2v	78	30	than	than	IN
cord-344382-vge4ho2v	78	31	wild	wild	JJ
cord-344382-vge4ho2v	78	32	-	-	HYPH
cord-344382-vge4ho2v	78	33	type	type	NN
cord-344382-vge4ho2v	78	34	mice	mouse	NNS
cord-344382-vge4ho2v	78	35	.	.	.
cord-344382-vge4ho2v	79	1	22	22	CD
cord-344382-vge4ho2v	79	2	Preliminary	preliminary	JJ
cord-344382-vge4ho2v	79	3	data	datum	NNS
cord-344382-vge4ho2v	79	4	provide	provide	VBP
cord-344382-vge4ho2v	79	5	evidence	evidence	NN
cord-344382-vge4ho2v	79	6	for	for	IN
cord-344382-vge4ho2v	79	7	activation	activation	NN
cord-344382-vge4ho2v	79	8	of	of	IN
cord-344382-vge4ho2v	79	9	complement	complement	NN
cord-344382-vge4ho2v	79	10	(	(	-LRB-
cord-344382-vge4ho2v	79	11	sC5b-9	sc5b-9	NN
cord-344382-vge4ho2v	79	12	and	and	CC
cord-344382-vge4ho2v	79	13	C5a	C5a	NNS
cord-344382-vge4ho2v	79	14	)	)	-RRB-
cord-344382-vge4ho2v	79	15	in	in	IN
cord-344382-vge4ho2v	79	16	patients	patient	NNS
cord-344382-vge4ho2v	79	17	with	with	IN
cord-344382-vge4ho2v	79	18	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	79	19	,	,	,
cord-344382-vge4ho2v	79	20	with	with	IN
cord-344382-vge4ho2v	79	21	significantly	significantly	RB
cord-344382-vge4ho2v	79	22	higher	high	JJR
cord-344382-vge4ho2v	79	23	plasma	plasma	NN
cord-344382-vge4ho2v	79	24	levels	level	NNS
cord-344382-vge4ho2v	79	25	in	in	IN
cord-344382-vge4ho2v	79	26	the	the	DT
cord-344382-vge4ho2v	79	27	patients	patient	NNS
cord-344382-vge4ho2v	79	28	with	with	IN
cord-344382-vge4ho2v	79	29	severe	severe	JJ
cord-344382-vge4ho2v	79	30	disease	disease	NN
cord-344382-vge4ho2v	79	31	than	than	IN
cord-344382-vge4ho2v	79	32	in	in	IN
cord-344382-vge4ho2v	79	33	those	those	DT
cord-344382-vge4ho2v	79	34	with	with	IN
cord-344382-vge4ho2v	79	35	moderate	moderate	JJ
cord-344382-vge4ho2v	79	36	disease	disease	NN
cord-344382-vge4ho2v	79	37	.	.	.
cord-344382-vge4ho2v	80	1	Hence	hence	RB
cord-344382-vge4ho2v	80	2	,	,	,
cord-344382-vge4ho2v	80	3	complement	complement	JJ
cord-344382-vge4ho2v	80	4	activation	activation	NN
cord-344382-vge4ho2v	80	5	has	have	VBZ
cord-344382-vge4ho2v	80	6	been	be	VBN
cord-344382-vge4ho2v	80	7	suggested	suggest	VBN
cord-344382-vge4ho2v	80	8	as	as	IN
cord-344382-vge4ho2v	80	9	a	a	DT
cord-344382-vge4ho2v	80	10	novel	novel	JJ
cord-344382-vge4ho2v	80	11	therapeutic	therapeutic	JJ
cord-344382-vge4ho2v	80	12	target	target	NN
cord-344382-vge4ho2v	80	13	in	in	IN
cord-344382-vge4ho2v	80	14	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	80	15	.	.	.
cord-344382-vge4ho2v	80	16	21	21	CD
cord-344382-vge4ho2v	81	1	In	in	IN
cord-344382-vge4ho2v	81	2	this	this	DT
cord-344382-vge4ho2v	81	3	context	context	NN
cord-344382-vge4ho2v	81	4	,	,	,
cord-344382-vge4ho2v	81	5	it	-PRON-	PRP
cord-344382-vge4ho2v	81	6	is	be	VBZ
cord-344382-vge4ho2v	81	7	noteworthy	noteworthy	JJ
cord-344382-vge4ho2v	81	8	that	that	IN
cord-344382-vge4ho2v	81	9	administration	administration	NN
cord-344382-vge4ho2v	81	10	of	of	IN
cord-344382-vge4ho2v	81	11	NAC	NAC	NNP
cord-344382-vge4ho2v	81	12	(	(	-LRB-
cord-344382-vge4ho2v	81	13	2	2	CD
cord-344382-vge4ho2v	81	14	×	×	NN
cord-344382-vge4ho2v	81	15	600	600	CD
cord-344382-vge4ho2v	81	16	mg	mg	NNP
cord-344382-vge4ho2v	81	17	/	/	SYM
cord-344382-vge4ho2v	81	18	day	day	NN
cord-344382-vge4ho2v	81	19	for	for	IN
cord-344382-vge4ho2v	81	20	8	8	CD
cord-344382-vge4ho2v	81	21	weeks	week	NNS
cord-344382-vge4ho2v	81	22	)	)	-RRB-
cord-344382-vge4ho2v	81	23	in	in	IN
cord-344382-vge4ho2v	81	24	a	a	DT
cord-344382-vge4ho2v	81	25	placebo	placebo	NN
cord-344382-vge4ho2v	81	26	-	-	HYPH
cord-344382-vge4ho2v	81	27	controlled	control	VBN
cord-344382-vge4ho2v	81	28	study	study	NN
cord-344382-vge4ho2v	81	29	has	have	VBZ
cord-344382-vge4ho2v	81	30	been	be	VBN
cord-344382-vge4ho2v	81	31	shown	show	VBN
cord-344382-vge4ho2v	81	32	to	to	TO
cord-344382-vge4ho2v	81	33	reduce	reduce	VB
cord-344382-vge4ho2v	81	34	the	the	DT
cord-344382-vge4ho2v	81	35	plasma	plasma	NN
cord-344382-vge4ho2v	81	36	levels	level	NNS
cord-344382-vge4ho2v	81	37	of	of	IN
cord-344382-vge4ho2v	81	38	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	81	39	markers	marker	NNS
cord-344382-vge4ho2v	81	40	,	,	,
cord-344382-vge4ho2v	81	41	including	include	VBG
cord-344382-vge4ho2v	81	42	complement	complement	NN
cord-344382-vge4ho2v	81	43	(	(	-LRB-
cord-344382-vge4ho2v	81	44	C3	C3	NNP
cord-344382-vge4ho2v	81	45	)	)	-RRB-
cord-344382-vge4ho2v	81	46	,	,	,
cord-344382-vge4ho2v	81	47	in	in	IN
cord-344382-vge4ho2v	81	48	peritoneal	peritoneal	JJ
cord-344382-vge4ho2v	81	49	dialysis	dialysis	NN
cord-344382-vge4ho2v	81	50	patients	patient	NNS
cord-344382-vge4ho2v	81	51	.	.	.
cord-344382-vge4ho2v	82	1	23	23	CD
cord-344382-vge4ho2v	82	2	Chronic	chronic	JJ
cord-344382-vge4ho2v	82	3	oxidative	oxidative	JJ
cord-344382-vge4ho2v	82	4	stress	stress	NN
cord-344382-vge4ho2v	82	5	,	,	,
cord-344382-vge4ho2v	82	6	causing	cause	VBG
cord-344382-vge4ho2v	82	7	biomolecular	biomolecular	JJ
cord-344382-vge4ho2v	82	8	damage	damage	NN
cord-344382-vge4ho2v	82	9	,	,	,
cord-344382-vge4ho2v	82	10	contributes	contribute	VBZ
cord-344382-vge4ho2v	82	11	to	to	IN
cord-344382-vge4ho2v	82	12	the	the	DT
cord-344382-vge4ho2v	82	13	age	age	NN
cord-344382-vge4ho2v	82	14	-	-	HYPH
cord-344382-vge4ho2v	82	15	related	relate	VBN
cord-344382-vge4ho2v	82	16	decline	decline	NN
cord-344382-vge4ho2v	82	17	in	in	IN
cord-344382-vge4ho2v	82	18	physiological	physiological	JJ
cord-344382-vge4ho2v	82	19	functions	function	NNS
cord-344382-vge4ho2v	82	20	,	,	,
cord-344382-vge4ho2v	82	21	including	include	VBG
cord-344382-vge4ho2v	82	22	the	the	DT
cord-344382-vge4ho2v	82	23	immune	immune	JJ
cord-344382-vge4ho2v	82	24	function	function	NN
cord-344382-vge4ho2v	82	25	.	.	.
cord-344382-vge4ho2v	83	1	The	the	DT
cord-344382-vge4ho2v	83	2	daily	daily	JJ
cord-344382-vge4ho2v	83	3	administration	administration	NN
cord-344382-vge4ho2v	83	4	of	of	IN
cord-344382-vge4ho2v	83	5	NAC	NAC	NNP
cord-344382-vge4ho2v	83	6	(	(	-LRB-
cord-344382-vge4ho2v	83	7	600	600	CD
cord-344382-vge4ho2v	83	8	mg	mg	NN
cord-344382-vge4ho2v	83	9	)	)	-RRB-
cord-344382-vge4ho2v	83	10	to	to	IN
cord-344382-vge4ho2v	83	11	postmenopausal	postmenopausal	JJ
cord-344382-vge4ho2v	83	12	women	woman	NNS
cord-344382-vge4ho2v	83	13	strengthened	strengthen	VBD
cord-344382-vge4ho2v	83	14	the	the	DT
cord-344382-vge4ho2v	83	15	immune	immune	JJ
cord-344382-vge4ho2v	83	16	defenses	defense	NNS
cord-344382-vge4ho2v	83	17	thereby	thereby	RB
cord-344382-vge4ho2v	83	18	decreasing	decrease	VBG
cord-344382-vge4ho2v	83	19	the	the	DT
cord-344382-vge4ho2v	83	20	probability	probability	NN
cord-344382-vge4ho2v	83	21	of	of	IN
cord-344382-vge4ho2v	83	22	immune	immune	JJ
cord-344382-vge4ho2v	83	23	system	system	NN
cord-344382-vge4ho2v	83	24	-	-	HYPH
cord-344382-vge4ho2v	83	25	related	relate	VBN
cord-344382-vge4ho2v	83	26	diseases	disease	NNS
cord-344382-vge4ho2v	83	27	in	in	IN
cord-344382-vge4ho2v	83	28	aging	age	VBG
cord-344382-vge4ho2v	83	29	,	,	,
cord-344382-vge4ho2v	83	30	such	such	JJ
cord-344382-vge4ho2v	83	31	as	as	IN
cord-344382-vge4ho2v	83	32	infections	infection	NNS
cord-344382-vge4ho2v	83	33	,	,	,
cord-344382-vge4ho2v	83	34	as	as	IN
cord-344382-vge4ho2v	83	35	shown	show	VBN
cord-344382-vge4ho2v	83	36	by	by	IN
cord-344382-vge4ho2v	83	37	monitoring	monitor	VBG
cord-344382-vge4ho2v	83	38	several	several	JJ
cord-344382-vge4ho2v	83	39	lymphocyte	lymphocyte	NN
cord-344382-vge4ho2v	83	40	functions	function	NNS
cord-344382-vge4ho2v	83	41	(	(	-LRB-
cord-344382-vge4ho2v	83	42	adherence	adherence	NN
cord-344382-vge4ho2v	83	43	,	,	,
cord-344382-vge4ho2v	83	44	chemotaxis	chemotaxis	NN
cord-344382-vge4ho2v	83	45	,	,	,
cord-344382-vge4ho2v	83	46	proliferation	proliferation	NN
cord-344382-vge4ho2v	83	47	,	,	,
cord-344382-vge4ho2v	83	48	and	and	CC
cord-344382-vge4ho2v	83	49	natural	natural	JJ
cord-344382-vge4ho2v	83	50	killer	killer	NN
cord-344382-vge4ho2v	83	51	activity	activity	NN
cord-344382-vge4ho2v	83	52	)	)	-RRB-
cord-344382-vge4ho2v	83	53	and	and	CC
cord-344382-vge4ho2v	83	54	neutrophil	neutrophil	NN
cord-344382-vge4ho2v	83	55	functions	function	NNS
cord-344382-vge4ho2v	83	56	(	(	-LRB-
cord-344382-vge4ho2v	83	57	adherence	adherence	NN
cord-344382-vge4ho2v	83	58	,	,	,
cord-344382-vge4ho2v	83	59	chemotaxis	chemotaxis	NN
cord-344382-vge4ho2v	83	60	,	,	,
cord-344382-vge4ho2v	83	61	phagocytosis	phagocytosis	NN
cord-344382-vge4ho2v	83	62	,	,	,
cord-344382-vge4ho2v	83	63	and	and	CC
cord-344382-vge4ho2v	83	64	superoxide	superoxide	NN
cord-344382-vge4ho2v	83	65	)	)	-RRB-
cord-344382-vge4ho2v	83	66	as	as	RB
cord-344382-vge4ho2v	83	67	well	well	RB
cord-344382-vge4ho2v	83	68	as	as	IN
cord-344382-vge4ho2v	83	69	cytokine	cytokine	NN
cord-344382-vge4ho2v	83	70	levels	level	NNS
cord-344382-vge4ho2v	83	71	(	(	-LRB-
cord-344382-vge4ho2v	83	72	IL-2	IL-2	NNP
cord-344382-vge4ho2v	83	73	,	,	,
cord-344382-vge4ho2v	83	74	IL-8	IL-8	NNP
cord-344382-vge4ho2v	83	75	,	,	,
cord-344382-vge4ho2v	83	76	and	and	CC
cord-344382-vge4ho2v	83	77	TNF	TNF	NNP
cord-344382-vge4ho2v	83	78	-	-	HYPH
cord-344382-vge4ho2v	83	79	α	α	NNP
cord-344382-vge4ho2v	83	80	)	)	-RRB-
cord-344382-vge4ho2v	83	81	.	.	.
cord-344382-vge4ho2v	84	1	24	24	CD
cord-344382-vge4ho2v	84	2	 	 	_SP
cord-344382-vge4ho2v	85	1	NAC	NAC	NNP
cord-344382-vge4ho2v	85	2	works	work	VBZ
cord-344382-vge4ho2v	85	3	via	via	IN
cord-344382-vge4ho2v	85	4	a	a	DT
cord-344382-vge4ho2v	85	5	broad	broad	JJ
cord-344382-vge4ho2v	85	6	variety	variety	NN
cord-344382-vge4ho2v	85	7	of	of	IN
cord-344382-vge4ho2v	85	8	mechanisms	mechanism	NNS
cord-344382-vge4ho2v	85	9	,	,	,
cord-344382-vge4ho2v	85	10	which	which	WDT
cord-344382-vge4ho2v	85	11	inside	inside	IN
cord-344382-vge4ho2v	85	12	cells	cell	NNS
cord-344382-vge4ho2v	85	13	are	be	VBP
cord-344382-vge4ho2v	85	14	mediated	mediate	VBN
cord-344382-vge4ho2v	85	15	by	by	IN
cord-344382-vge4ho2v	85	16	GSH	GSH	NNP
cord-344382-vge4ho2v	85	17	replenishment	replenishment	NN
cord-344382-vge4ho2v	85	18	.	.	.
cord-344382-vge4ho2v	86	1	A	a	DT
cord-344382-vge4ho2v	86	2	major	major	JJ
cord-344382-vge4ho2v	86	3	one	one	NN
cord-344382-vge4ho2v	86	4	is	be	VBZ
cord-344382-vge4ho2v	86	5	its	-PRON-	PRP$
cord-344382-vge4ho2v	86	6	nucleophilicity	nucleophilicity	NN
cord-344382-vge4ho2v	86	7	,	,	,
cord-344382-vge4ho2v	86	8	which	which	WDT
cord-344382-vge4ho2v	86	9	consists	consist	VBZ
cord-344382-vge4ho2v	86	10	of	of	IN
cord-344382-vge4ho2v	86	11	the	the	DT
cord-344382-vge4ho2v	86	12	ability	ability	NN
cord-344382-vge4ho2v	86	13	of	of	IN
cord-344382-vge4ho2v	86	14	sulfhydryl	sulfhydryl	NN
cord-344382-vge4ho2v	86	15	groups	group	NNS
cord-344382-vge4ho2v	86	16	(	(	-LRB-
cord-344382-vge4ho2v	86	17	-SH	-SH	NNS
cord-344382-vge4ho2v	86	18	)	)	-RRB-
cord-344382-vge4ho2v	86	19	to	to	TO
cord-344382-vge4ho2v	86	20	react	react	VB
cord-344382-vge4ho2v	86	21	with	with	IN
cord-344382-vge4ho2v	86	22	electrophilic	electrophilic	JJ
cord-344382-vge4ho2v	86	23	metabolites	metabolite	NNS
cord-344382-vge4ho2v	86	24	,	,	,
cord-344382-vge4ho2v	86	25	either	either	CC
cord-344382-vge4ho2v	86	26	directly	directly	RB
cord-344382-vge4ho2v	86	27	or	or	CC
cord-344382-vge4ho2v	86	28	via	via	IN
cord-344382-vge4ho2v	87	1	GSH	GSH	NNP
cord-344382-vge4ho2v	87	2	S	S	NNP
cord-344382-vge4ho2v	87	3	-	-	HYPH
cord-344382-vge4ho2v	87	4	transferases	transferase	NNS
cord-344382-vge4ho2v	87	5	.	.	.
cord-344382-vge4ho2v	88	1	17	17	CD
cord-344382-vge4ho2v	89	1	This	this	DT
cord-344382-vge4ho2v	89	2	property	property	NN
cord-344382-vge4ho2v	89	3	results	result	NNS
cord-344382-vge4ho2v	89	4	in	in	IN
cord-344382-vge4ho2v	89	5	binding	binding	NN
cord-344382-vge4ho2v	89	6	of	of	IN
cord-344382-vge4ho2v	89	7	DNA	dna	NN
cord-344382-vge4ho2v	89	8	reactive	reactive	JJ
cord-344382-vge4ho2v	89	9	metabolites	metabolite	NNS
cord-344382-vge4ho2v	89	10	and	and	CC
cord-344382-vge4ho2v	89	11	in	in	IN
cord-344382-vge4ho2v	89	12	blocking	block	VBG
cord-344382-vge4ho2v	89	13	reactive	reactive	JJ
cord-344382-vge4ho2v	89	14	intermediates	intermediate	NNS
cord-344382-vge4ho2v	89	15	.	.	.
cord-344382-vge4ho2v	90	1	An	an	DT
cord-344382-vge4ho2v	90	2	example	example	NN
cord-344382-vge4ho2v	90	3	of	of	IN
cord-344382-vge4ho2v	90	4	reactive	reactive	JJ
cord-344382-vge4ho2v	90	5	intermediate	intermediate	NN
cord-344382-vge4ho2v	90	6	is	be	VBZ
cord-344382-vge4ho2v	90	7	the	the	DT
cord-344382-vge4ho2v	90	8	paracetamol	paracetamol	NNP
cord-344382-vge4ho2v	90	9	metabolite	metabolite	NNP
cord-344382-vge4ho2v	90	10	N	N	NNP
cord-344382-vge4ho2v	90	11	-	-	HYPH
cord-344382-vge4ho2v	90	12	acetyl	acetyl	NNP
cord-344382-vge4ho2v	90	13	-	-	HYPH
cord-344382-vge4ho2v	90	14	p	p	NN
cord-344382-vge4ho2v	90	15	-	-	HYPH
cord-344382-vge4ho2v	90	16	benzoquinone	benzoquinone	NN
cord-344382-vge4ho2v	90	17	imine	imine	NN
cord-344382-vge4ho2v	90	18	(	(	-LRB-
cord-344382-vge4ho2v	90	19	NAPQI	NAPQI	NNP
cord-344382-vge4ho2v	90	20	)	)	-RRB-
cord-344382-vge4ho2v	90	21	formed	form	VBD
cord-344382-vge4ho2v	90	22	via	via	IN
cord-344382-vge4ho2v	90	23	cytochrome	cytochrome	NN
cord-344382-vge4ho2v	90	24	P450	p450	JJ
cord-344382-vge4ho2v	90	25	enzymes	enzyme	NNS
cord-344382-vge4ho2v	90	26	.	.	.
cord-344382-vge4ho2v	91	1	In	in	IN
cord-344382-vge4ho2v	91	2	addition	addition	NN
cord-344382-vge4ho2v	91	3	,	,	,
cord-344382-vge4ho2v	91	4	NAC	NAC	NNP
cord-344382-vge4ho2v	91	5	can	can	MD
cord-344382-vge4ho2v	91	6	exert	exert	VB
cord-344382-vge4ho2v	91	7	antioxidant	antioxidant	JJ
cord-344382-vge4ho2v	91	8	activity	activity	NN
cord-344382-vge4ho2v	91	9	via	via	IN
cord-344382-vge4ho2v	91	10	p53-mediated	p53-mediated	JJ
cord-344382-vge4ho2v	91	11	apoptosis	apoptosis	NN
cord-344382-vge4ho2v	91	12	.	.	.
cord-344382-vge4ho2v	92	1	25	25	CD
cord-344382-vge4ho2v	92	2	L	L	NNP
cord-344382-vge4ho2v	92	3	-	-	HYPH
cord-344382-vge4ho2v	92	4	Cys	Cys	NNP
cord-344382-vge4ho2v	92	5	,	,	,
cord-344382-vge4ho2v	92	6	derived	derive	VBN
cord-344382-vge4ho2v	92	7	by	by	IN
cord-344382-vge4ho2v	92	8	NAC	NAC	NNP
cord-344382-vge4ho2v	92	9	catabolism	catabolism	NN
cord-344382-vge4ho2v	92	10	,	,	,
cord-344382-vge4ho2v	92	11	is	be	VBZ
cord-344382-vge4ho2v	92	12	readily	readily	RB
cord-344382-vge4ho2v	92	13	bioconverted	bioconverte	VBN
cord-344382-vge4ho2v	92	14	to	to	IN
cord-344382-vge4ho2v	92	15	the	the	DT
cord-344382-vge4ho2v	92	16	vasodilator	vasodilator	NN
cord-344382-vge4ho2v	92	17	,	,	,
cord-344382-vge4ho2v	92	18	anti	anti	JJ
cord-344382-vge4ho2v	92	19	-	-	JJ
cord-344382-vge4ho2v	92	20	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	92	21	and	and	CC
cord-344382-vge4ho2v	92	22	readily	readily	RB
cord-344382-vge4ho2v	92	23	diffusible	diffusible	JJ
cord-344382-vge4ho2v	92	24	hydrogen	hydrogen	NN
cord-344382-vge4ho2v	92	25	sulfide	sulfide	NN
cord-344382-vge4ho2v	92	26	.	.	.
cord-344382-vge4ho2v	93	1	Therefore	therefore	RB
cord-344382-vge4ho2v	93	2	,	,	,
cord-344382-vge4ho2v	93	3	NAC	NAC	NNP
cord-344382-vge4ho2v	93	4	should	should	MD
cord-344382-vge4ho2v	93	5	be	be	VB
cord-344382-vge4ho2v	93	6	regarded	regard	VBN
cord-344382-vge4ho2v	93	7	as	as	IN
cord-344382-vge4ho2v	93	8	a	a	DT
cord-344382-vge4ho2v	93	9	hydrogen	hydrogen	NN
cord-344382-vge4ho2v	93	10	sulfide	sulfide	NN
cord-344382-vge4ho2v	93	11	donor	donor	NN
cord-344382-vge4ho2v	93	12	.	.	.
cord-344382-vge4ho2v	94	1	26	26	CD
cord-344382-vge4ho2v	95	1	Some	some	DT
cord-344382-vge4ho2v	95	2	major	major	JJ
cord-344382-vge4ho2v	95	3	mechanisms	mechanism	NNS
cord-344382-vge4ho2v	95	4	responsible	responsible	JJ
cord-344382-vge4ho2v	95	5	for	for	IN
cord-344382-vge4ho2v	95	6	the	the	DT
cord-344382-vge4ho2v	95	7	antioxidant/	antioxidant/	JJ
cord-344382-vge4ho2v	95	8	anti	anti	JJ
cord-344382-vge4ho2v	95	9	-	-	JJ
cord-344382-vge4ho2v	95	10	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	95	11	properties	property	NNS
cord-344382-vge4ho2v	95	12	of	of	IN
cord-344382-vge4ho2v	95	13	NAC	NAC	NNP
cord-344382-vge4ho2v	95	14	are	be	VBP
cord-344382-vge4ho2v	95	15	summarized	summarize	VBN
cord-344382-vge4ho2v	95	16	in	in	IN
cord-344382-vge4ho2v	95	17	Figure	Figure	NNP
cord-344382-vge4ho2v	95	18	1	1	CD
cord-344382-vge4ho2v	95	19	.	.	.
cord-344382-vge4ho2v	96	1	First	first	RB
cord-344382-vge4ho2v	96	2	of	of	IN
cord-344382-vge4ho2v	96	3	all	all	DT
cord-344382-vge4ho2v	96	4	,	,	,
cord-344382-vge4ho2v	96	5	it	-PRON-	PRP
cord-344382-vge4ho2v	96	6	has	have	VBZ
cord-344382-vge4ho2v	96	7	been	be	VBN
cord-344382-vge4ho2v	96	8	established	establish	VBN
cord-344382-vge4ho2v	96	9	for	for	IN
cord-344382-vge4ho2v	96	10	a	a	DT
cord-344382-vge4ho2v	96	11	long	long	JJ
cord-344382-vge4ho2v	96	12	time	time	NN
cord-344382-vge4ho2v	96	13	that	that	WDT
cord-344382-vge4ho2v	96	14	NAC	NAC	NNP
cord-344382-vge4ho2v	96	15	is	be	VBZ
cord-344382-vge4ho2v	96	16	a	a	DT
cord-344382-vge4ho2v	96	17	potent	potent	JJ
cord-344382-vge4ho2v	96	18	scavenger	scavenger	NN
cord-344382-vge4ho2v	96	19	of	of	IN
cord-344382-vge4ho2v	96	20	ROS	ROS	NNP
cord-344382-vge4ho2v	96	21	and	and	CC
cord-344382-vge4ho2v	96	22	especially	especially	RB
cord-344382-vge4ho2v	96	23	of	of	IN
cord-344382-vge4ho2v	96	24	hypochlorous	hypochlorous	JJ
cord-344382-vge4ho2v	96	25	acid	acid	NN
cord-344382-vge4ho2v	96	26	(	(	-LRB-
cord-344382-vge4ho2v	96	27	HOCl	HOCl	NNP
cord-344382-vge4ho2v	96	28	)	)	-RRB-
cord-344382-vge4ho2v	96	29	and	and	CC
cord-344382-vge4ho2v	96	30	•OH	•OH	NNP
cord-344382-vge4ho2v	96	31	.	.	.
cord-344382-vge4ho2v	97	1	27	27	CD
cord-344382-vge4ho2v	97	2	Inhibition	inhibition	NN
cord-344382-vge4ho2v	97	3	by	by	IN
cord-344382-vge4ho2v	97	4	NAC	NAC	NNP
cord-344382-vge4ho2v	97	5	of	of	IN
cord-344382-vge4ho2v	97	6	the	the	DT
cord-344382-vge4ho2v	97	7	ROS	ROS	NNP
cord-344382-vge4ho2v	97	8	-	-	HYPH
cord-344382-vge4ho2v	97	9	producing	produce	VBG
cord-344382-vge4ho2v	97	10	vascular	vascular	JJ
cord-344382-vge4ho2v	97	11	NAD(P)H	NAD(P)H	NNP
cord-344382-vge4ho2v	97	12	oxidases	oxidase	NNS
cord-344382-vge4ho2v	97	13	is	be	VBZ
cord-344382-vge4ho2v	97	14	relevant	relevant	JJ
cord-344382-vge4ho2v	97	15	to	to	IN
cord-344382-vge4ho2v	97	16	prevention	prevention	NN
cord-344382-vge4ho2v	97	17	of	of	IN
cord-344382-vge4ho2v	97	18	hypertension	hypertension	NN
cord-344382-vge4ho2v	97	19	and	and	CC
cord-344382-vge4ho2v	97	20	to	to	IN
cord-344382-vge4ho2v	97	21	pathological	pathological	JJ
cord-344382-vge4ho2v	97	22	states	state	NNS
cord-344382-vge4ho2v	97	23	associated	associate	VBN
cord-344382-vge4ho2v	97	24	with	with	IN
cord-344382-vge4ho2v	97	25	uncontrolled	uncontrolled	JJ
cord-344382-vge4ho2v	97	26	growth	growth	NN
cord-344382-vge4ho2v	97	27	and	and	CC
cord-344382-vge4ho2v	97	28	inflammation	inflammation	NN
cord-344382-vge4ho2v	97	29	,	,	,
cord-344382-vge4ho2v	97	30	such	such	JJ
cord-344382-vge4ho2v	97	31	as	as	IN
cord-344382-vge4ho2v	97	32	atherosclerosis	atherosclerosis	NN
cord-344382-vge4ho2v	97	33	.	.	.
cord-344382-vge4ho2v	98	1	28	28	CD
cord-344382-vge4ho2v	99	1	The	the	DT
cord-344382-vge4ho2v	99	2	SH	sh	NN
cord-344382-vge4ho2v	99	3	-	-	HYPH
cord-344382-vge4ho2v	99	4	groups	group	NNS
cord-344382-vge4ho2v	99	5	within	within	IN
cord-344382-vge4ho2v	99	6	the	the	DT
cord-344382-vge4ho2v	99	7	NAC	NAC	NNP
cord-344382-vge4ho2v	99	8	molecule	molecule	NN
cord-344382-vge4ho2v	99	9	can	can	MD
cord-344382-vge4ho2v	99	10	also	also	RB
cord-344382-vge4ho2v	99	11	scavenge	scavenge	VB
cord-344382-vge4ho2v	99	12	several	several	JJ
cord-344382-vge4ho2v	99	13	reactive	reactive	JJ
cord-344382-vge4ho2v	99	14	nitrogen	nitrogen	NN
cord-344382-vge4ho2v	99	15	species	specie	NNS
cord-344382-vge4ho2v	99	16	(	(	-LRB-
cord-344382-vge4ho2v	99	17	RNS	RNS	NNP
cord-344382-vge4ho2v	99	18	)	)	-RRB-
cord-344382-vge4ho2v	99	19	that	that	WDT
cord-344382-vge4ho2v	99	20	play	play	VBP
cord-344382-vge4ho2v	99	21	a	a	DT
cord-344382-vge4ho2v	99	22	role	role	NN
cord-344382-vge4ho2v	99	23	in	in	IN
cord-344382-vge4ho2v	99	24	the	the	DT
cord-344382-vge4ho2v	99	25	oxidation	oxidation	NN
cord-344382-vge4ho2v	99	26	of	of	IN
cord-344382-vge4ho2v	99	27	lipids	lipid	NNS
cord-344382-vge4ho2v	99	28	,	,	,
cord-344382-vge4ho2v	99	29	proteins	protein	NNS
cord-344382-vge4ho2v	99	30	,	,	,
cord-344382-vge4ho2v	99	31	and	and	CC
cord-344382-vge4ho2v	99	32	DNA	dna	NN
cord-344382-vge4ho2v	99	33	.	.	.
cord-344382-vge4ho2v	100	1	29	29	CD
cord-344382-vge4ho2v	101	1	NAC	NAC	NNP
cord-344382-vge4ho2v	101	2	potentiates	potentiate	VBZ
cord-344382-vge4ho2v	101	3	the	the	DT
cord-344382-vge4ho2v	101	4	vasodilator	vasodilator	NN
cord-344382-vge4ho2v	101	5	and	and	CC
cord-344382-vge4ho2v	101	6	antiaggregatory	antiaggregatory	NN
cord-344382-vge4ho2v	101	7	effects	effect	NNS
cord-344382-vge4ho2v	101	8	of	of	IN
cord-344382-vge4ho2v	101	9	nitric	nitric	NN
cord-344382-vge4ho2v	101	10	oxide	oxide	NN
cord-344382-vge4ho2v	101	11	,	,	,
cord-344382-vge4ho2v	101	12	which	which	WDT
cord-344382-vge4ho2v	101	13	is	be	VBZ
cord-344382-vge4ho2v	101	14	a	a	DT
cord-344382-vge4ho2v	101	15	very	very	RB
cord-344382-vge4ho2v	101	16	important	important	JJ
cord-344382-vge4ho2v	101	17	interaction	interaction	NN
cord-344382-vge4ho2v	101	18	clinically	clinically	RB
cord-344382-vge4ho2v	101	19	,	,	,
cord-344382-vge4ho2v	101	20	and	and	CC
cord-344382-vge4ho2v	101	21	which	which	WDT
cord-344382-vge4ho2v	101	22	has	have	VBZ
cord-344382-vge4ho2v	101	23	been	be	VBN
cord-344382-vge4ho2v	101	24	shown	show	VBN
cord-344382-vge4ho2v	101	25	to	to	TO
cord-344382-vge4ho2v	101	26	be	be	VB
cord-344382-vge4ho2v	101	27	valuable	valuable	JJ
cord-344382-vge4ho2v	101	28	in	in	IN
cord-344382-vge4ho2v	101	29	the	the	DT
cord-344382-vge4ho2v	101	30	context	context	NN
cord-344382-vge4ho2v	101	31	of	of	IN
cord-344382-vge4ho2v	101	32	acute	acute	JJ
cord-344382-vge4ho2v	101	33	heart	heart	NN
cord-344382-vge4ho2v	101	34	failure	failure	NN
cord-344382-vge4ho2v	101	35	and	and	CC
cord-344382-vge4ho2v	101	36	acute	acute	JJ
cord-344382-vge4ho2v	101	37	myocardial	myocardial	JJ
cord-344382-vge4ho2v	101	38	ischemia	ischemia	NN
cord-344382-vge4ho2v	101	39	and	and	CC
cord-344382-vge4ho2v	101	40	infarction	infarction	NN
cord-344382-vge4ho2v	101	41	.	.	.
cord-344382-vge4ho2v	102	1	30	30	CD
cord-344382-vge4ho2v	102	2	Inhibition	inhibition	NN
cord-344382-vge4ho2v	102	3	by	by	IN
cord-344382-vge4ho2v	102	4	NAC	NAC	NNP
cord-344382-vge4ho2v	102	5	of	of	IN
cord-344382-vge4ho2v	102	6	epidermal	epidermal	JJ
cord-344382-vge4ho2v	102	7	growth	growth	NN
cord-344382-vge4ho2v	102	8	factor	factor	NN
cord-344382-vge4ho2v	102	9	receptor	receptor	NN
cord-344382-vge4ho2v	102	10	(	(	-LRB-
cord-344382-vge4ho2v	102	11	EGFR	EGFR	NNP
cord-344382-vge4ho2v	102	12	)	)	-RRB-
cord-344382-vge4ho2v	102	13	,	,	,
cord-344382-vge4ho2v	102	14	a	a	DT
cord-344382-vge4ho2v	102	15	tyrosine	tyrosine	NN
cord-344382-vge4ho2v	102	16	kinase	kinase	NN
cord-344382-vge4ho2v	102	17	involved	involve	VBN
cord-344382-vge4ho2v	102	18	in	in	IN
cord-344382-vge4ho2v	102	19	inflammation	inflammation	NN
cord-344382-vge4ho2v	102	20	,	,	,
cord-344382-vge4ho2v	102	21	14	14	CD
cord-344382-vge4ho2v	102	22	,	,	,
cord-344382-vge4ho2v	102	23	31	31	CD
cord-344382-vge4ho2v	102	24	also	also	RB
cord-344382-vge4ho2v	102	25	results	result	VBZ
cord-344382-vge4ho2v	102	26	in	in	IN
cord-344382-vge4ho2v	102	27	a	a	DT
cord-344382-vge4ho2v	102	28	decreased	decreased	JJ
cord-344382-vge4ho2v	102	29	inactivation	inactivation	NN
cord-344382-vge4ho2v	102	30	of	of	IN
cord-344382-vge4ho2v	102	31	α1-antitrypsin	α1-antitrypsin	NNS
cord-344382-vge4ho2v	102	32	.	.	.
cord-344382-vge4ho2v	103	1	In	in	IN
cord-344382-vge4ho2v	103	2	particular	particular	JJ
cord-344382-vge4ho2v	103	3	,	,	,
cord-344382-vge4ho2v	103	4	NAC	NAC	NNP
cord-344382-vge4ho2v	103	5	has	have	VBZ
cord-344382-vge4ho2v	103	6	the	the	DT
cord-344382-vge4ho2v	103	7	ability	ability	NN
cord-344382-vge4ho2v	103	8	to	to	TO
cord-344382-vge4ho2v	103	9	improve	improve	VB
cord-344382-vge4ho2v	103	10	the	the	DT
cord-344382-vge4ho2v	103	11	efficacy	efficacy	NN
cord-344382-vge4ho2v	103	12	and	and	CC
cord-344382-vge4ho2v	103	13	structural	structural	JJ
cord-344382-vge4ho2v	103	14	conformational	conformational	JJ
cord-344382-vge4ho2v	103	15	integrity	integrity	NN
cord-344382-vge4ho2v	103	16	of	of	IN
cord-344382-vge4ho2v	103	17	α1-antitrypsin	α1-antitrypsin	NNS
cord-344382-vge4ho2v	103	18	via	via	IN
cord-344382-vge4ho2v	103	19	a	a	DT
cord-344382-vge4ho2v	103	20	GSH	GSH	NNP
cord-344382-vge4ho2v	103	21	-	-	HYPH
cord-344382-vge4ho2v	103	22	mediated	mediate	VBN
cord-344382-vge4ho2v	103	23	mechanism	mechanism	NN
cord-344382-vge4ho2v	103	24	,	,	,
cord-344382-vge4ho2v	103	25	and	and	CC
cord-344382-vge4ho2v	103	26	it	-PRON-	PRP
cord-344382-vge4ho2v	103	27	enhances	enhance	VBZ
cord-344382-vge4ho2v	103	28	α1-antitrypsin	α1-antitrypsin	NNP
cord-344382-vge4ho2v	103	29	transcytosis	transcytosis	NNP
cord-344382-vge4ho2v	103	30	thus	thus	RB
cord-344382-vge4ho2v	103	31	improving	improve	VBG
cord-344382-vge4ho2v	103	32	its	-PRON-	PRP$
cord-344382-vge4ho2v	103	33	cellular	cellular	JJ
cord-344382-vge4ho2v	103	34	uptake	uptake	NN
cord-344382-vge4ho2v	103	35	and	and	CC
cord-344382-vge4ho2v	103	36	functions	function	NNS
cord-344382-vge4ho2v	103	37	.	.	.
cord-344382-vge4ho2v	104	1	32	32	CD
cord-344382-vge4ho2v	105	1	In	in	IN
cord-344382-vge4ho2v	105	2	experimental	experimental	JJ
cord-344382-vge4ho2v	105	3	studies	study	NNS
cord-344382-vge4ho2v	105	4	,	,	,
cord-344382-vge4ho2v	105	5	the	the	DT
cord-344382-vge4ho2v	105	6	oral	oral	JJ
cord-344382-vge4ho2v	105	7	administration	administration	NN
cord-344382-vge4ho2v	105	8	of	of	IN
cord-344382-vge4ho2v	105	9	NAC	NAC	NNP
cord-344382-vge4ho2v	105	10	to	to	IN
cord-344382-vge4ho2v	105	11	pregnant	pregnant	JJ
cord-344382-vge4ho2v	105	12	mice	mouse	NNS
cord-344382-vge4ho2v	105	13	enhanced	enhance	VBD
cord-344382-vge4ho2v	105	14	the	the	DT
cord-344382-vge4ho2v	105	15	expression	expression	NN
cord-344382-vge4ho2v	105	16	of	of	IN
cord-344382-vge4ho2v	105	17	the	the	DT
cord-344382-vge4ho2v	105	18	gene	gene	NN
cord-344382-vge4ho2v	105	19	encoding	encoding	NN
cord-344382-vge4ho2v	105	20	for	for	IN
cord-344382-vge4ho2v	105	21	an	an	DT
cord-344382-vge4ho2v	105	22	α1-antitrypsin	α1-antitrypsin	NNP
cord-344382-vge4ho2v	105	23	precursor	precursor	NN
cord-344382-vge4ho2v	105	24	in	in	IN
cord-344382-vge4ho2v	105	25	the	the	DT
cord-344382-vge4ho2v	105	26	fetal	fetal	JJ
cord-344382-vge4ho2v	105	27	liver	liver	NN
cord-344382-vge4ho2v	105	28	.	.	.
cord-344382-vge4ho2v	106	1	33	33	CD
cord-344382-vge4ho2v	106	2	Together	together	RB
cord-344382-vge4ho2v	106	3	with	with	IN
cord-344382-vge4ho2v	106	4	redox	redox	JJ
cord-344382-vge4ho2v	106	5	imbalance	imbalance	NN
cord-344382-vge4ho2v	106	6	,	,	,
cord-344382-vge4ho2v	106	7	α1-antitrypsin	α1-antitrypsin	JJ
cord-344382-vge4ho2v	106	8	deficiency	deficiency	NN
cord-344382-vge4ho2v	106	9	is	be	VBZ
cord-344382-vge4ho2v	106	10	involved	involve	VBN
cord-344382-vge4ho2v	106	11	in	in	IN
cord-344382-vge4ho2v	106	12	the	the	DT
cord-344382-vge4ho2v	106	13	pathogenesis	pathogenesis	NN
cord-344382-vge4ho2v	106	14	of	of	IN
cord-344382-vge4ho2v	106	15	COPD	COPD	NNP
cord-344382-vge4ho2v	106	16	.	.	.
cord-344382-vge4ho2v	107	1	NAC	NAC	NNP
cord-344382-vge4ho2v	107	2	was	be	VBD
cord-344382-vge4ho2v	107	3	found	find	VBN
cord-344382-vge4ho2v	107	4	to	to	TO
cord-344382-vge4ho2v	107	5	reduce	reduce	VB
cord-344382-vge4ho2v	107	6	IL-8	il-8	NN
cord-344382-vge4ho2v	107	7	levels	level	NNS
cord-344382-vge4ho2v	107	8	,	,	,
cord-344382-vge4ho2v	107	9	normalized	normalize	VBN
cord-344382-vge4ho2v	107	10	C	c	NN
cord-344382-vge4ho2v	107	11	-	-	HYPH
cord-344382-vge4ho2v	107	12	reactive	reactive	JJ
cord-344382-vge4ho2v	107	13	protein	protein	NN
cord-344382-vge4ho2v	107	14	(	(	-LRB-
cord-344382-vge4ho2v	107	15	CRP	CRP	NNP
cord-344382-vge4ho2v	107	16	)	)	-RRB-
cord-344382-vge4ho2v	107	17	levels	level	NNS
cord-344382-vge4ho2v	107	18	,	,	,
cord-344382-vge4ho2v	107	19	and	and	CC
cord-344382-vge4ho2v	107	20	improved	improve	VBN
cord-344382-vge4ho2v	107	21	clinical	clinical	JJ
cord-344382-vge4ho2v	107	22	outcomes	outcome	NNS
cord-344382-vge4ho2v	107	23	in	in	IN
cord-344382-vge4ho2v	107	24	patients	patient	NNS
cord-344382-vge4ho2v	107	25	with	with	IN
cord-344382-vge4ho2v	107	26	COPD	COPD	NNP
cord-344382-vge4ho2v	107	27	exacerbations	exacerbation	NNS
cord-344382-vge4ho2v	107	28	.	.	.
cord-344382-vge4ho2v	108	1	34	34	CD
cord-344382-vge4ho2v	109	1	A	a	DT
cord-344382-vge4ho2v	109	2	prospective	prospective	NN
cord-344382-vge4ho2v	109	3	,	,	,
cord-344382-vge4ho2v	109	4	randomized	randomized	JJ
cord-344382-vge4ho2v	109	5	,	,	,
cord-344382-vge4ho2v	109	6	controlled	control	VBN
cord-344382-vge4ho2v	109	7	trial	trial	NN
cord-344382-vge4ho2v	109	8	in	in	IN
cord-344382-vge4ho2v	109	9	the	the	DT
cord-344382-vge4ho2v	109	10	Shandong	Shandong	NNP
cord-344382-vge4ho2v	109	11	Province	Province	NNP
cord-344382-vge4ho2v	109	12	,	,	,
cord-344382-vge4ho2v	109	13	China	China	NNP
cord-344382-vge4ho2v	109	14	enrolling	enrol	VBG
cord-344382-vge4ho2v	109	15	adult	adult	NN
cord-344382-vge4ho2v	109	16	bronchiectasis	bronchiectasis	NN
cord-344382-vge4ho2v	109	17	patients	patient	NNS
cord-344382-vge4ho2v	109	18	with	with	IN
cord-344382-vge4ho2v	109	19	at	at	RB
cord-344382-vge4ho2v	109	20	least	least	RBS
cord-344382-vge4ho2v	109	21	two	two	CD
cord-344382-vge4ho2v	109	22	exacerbations	exacerbation	NNS
cord-344382-vge4ho2v	109	23	in	in	IN
cord-344382-vge4ho2v	109	24	the	the	DT
cord-344382-vge4ho2v	109	25	previous	previous	JJ
cord-344382-vge4ho2v	109	26	year	year	NN
cord-344382-vge4ho2v	109	27	showed	show	VBD
cord-344382-vge4ho2v	109	28	that	that	IN
cord-344382-vge4ho2v	109	29	oral	oral	JJ
cord-344382-vge4ho2v	109	30	NAC	NAC	NNP
cord-344382-vge4ho2v	109	31	(	(	-LRB-
cord-344382-vge4ho2v	109	32	600	600	CD
cord-344382-vge4ho2v	109	33	mg	mg	NN
cord-344382-vge4ho2v	109	34	twice	twice	RB
cord-344382-vge4ho2v	109	35	daily	daily	RB
cord-344382-vge4ho2v	109	36	for	for	IN
cord-344382-vge4ho2v	109	37	12	12	CD
cord-344382-vge4ho2v	109	38	months	month	NNS
cord-344382-vge4ho2v	109	39	)	)	-RRB-
cord-344382-vge4ho2v	109	40	was	be	VBD
cord-344382-vge4ho2v	109	41	able	able	JJ
cord-344382-vge4ho2v	109	42	to	to	TO
cord-344382-vge4ho2v	109	43	reduce	reduce	VB
cord-344382-vge4ho2v	109	44	the	the	DT
cord-344382-vge4ho2v	109	45	risk	risk	NN
cord-344382-vge4ho2v	109	46	of	of	IN
cord-344382-vge4ho2v	109	47	exacerbations	exacerbation	NNS
cord-344382-vge4ho2v	109	48	.	.	.
cord-344382-vge4ho2v	110	1	35	35	CD
cord-344382-vge4ho2v	111	1	In	in	IN
cord-344382-vge4ho2v	111	2	addition	addition	NN
cord-344382-vge4ho2v	111	3	,	,	,
cord-344382-vge4ho2v	111	4	NAC	NAC	NNP
cord-344382-vge4ho2v	111	5	has	have	VBZ
cord-344382-vge4ho2v	111	6	been	be	VBN
cord-344382-vge4ho2v	111	7	shown	show	VBN
cord-344382-vge4ho2v	111	8	to	to	TO
cord-344382-vge4ho2v	111	9	have	have	VB
cord-344382-vge4ho2v	111	10	protective	protective	JJ
cord-344382-vge4ho2v	111	11	effects	effect	NNS
cord-344382-vge4ho2v	111	12	in	in	IN
cord-344382-vge4ho2v	111	13	ARDS	ARDS	NNP
cord-344382-vge4ho2v	111	14	.	.	.
cord-344382-vge4ho2v	112	1	It	-PRON-	PRP
cord-344382-vge4ho2v	112	2	is	be	VBZ
cord-344382-vge4ho2v	112	3	well	well	RB
cord-344382-vge4ho2v	112	4	established	establish	VBN
cord-344382-vge4ho2v	112	5	that	that	IN
cord-344382-vge4ho2v	112	6	ROS	ROS	NNP
cord-344382-vge4ho2v	112	7	play	play	VB
cord-344382-vge4ho2v	112	8	a	a	DT
cord-344382-vge4ho2v	112	9	key	key	JJ
cord-344382-vge4ho2v	112	10	role	role	NN
cord-344382-vge4ho2v	112	11	in	in	IN
cord-344382-vge4ho2v	112	12	the	the	DT
cord-344382-vge4ho2v	112	13	pathogenesis	pathogenesis	NN
cord-344382-vge4ho2v	112	14	of	of	IN
cord-344382-vge4ho2v	112	15	the	the	DT
cord-344382-vge4ho2v	112	16	acute	acute	JJ
cord-344382-vge4ho2v	112	17	lung	lung	NN
cord-344382-vge4ho2v	112	18	injury	injury	NN
cord-344382-vge4ho2v	112	19	and	and	CC
cord-344382-vge4ho2v	112	20	that	that	IN
cord-344382-vge4ho2v	112	21	the	the	DT
cord-344382-vge4ho2v	112	22	alveolar	alveolar	JJ
cord-344382-vge4ho2v	112	23	epithelial	epithelial	JJ
cord-344382-vge4ho2v	112	24	lining	line	VBG
cord-344382-vge4ho2v	112	25	fluid	fluid	NN
cord-344382-vge4ho2v	112	26	of	of	IN
cord-344382-vge4ho2v	112	27	patients	patient	NNS
cord-344382-vge4ho2v	112	28	with	with	IN
cord-344382-vge4ho2v	112	29	ARDS	ARDS	NNP
cord-344382-vge4ho2v	112	30	is	be	VBZ
cord-344382-vge4ho2v	112	31	deficient	deficient	JJ
cord-344382-vge4ho2v	112	32	in	in	IN
cord-344382-vge4ho2v	112	33	GSH	GSH	NNP
cord-344382-vge4ho2v	112	34	,	,	,
cord-344382-vge4ho2v	112	35	which	which	WDT
cord-344382-vge4ho2v	112	36	may	may	MD
cord-344382-vge4ho2v	112	37	predispose	predispose	VB
cord-344382-vge4ho2v	112	38	these	these	DT
cord-344382-vge4ho2v	112	39	patients	patient	NNS
cord-344382-vge4ho2v	112	40	to	to	IN
cord-344382-vge4ho2v	112	41	that	that	DT
cord-344382-vge4ho2v	112	42	disease	disease	NN
cord-344382-vge4ho2v	112	43	.	.	.
cord-344382-vge4ho2v	113	1	36	36	CD
cord-344382-vge4ho2v	113	2	A	a	DT
cord-344382-vge4ho2v	113	3	randomized	randomized	JJ
cord-344382-vge4ho2v	113	4	,	,	,
cord-344382-vge4ho2v	113	5	double	double	JJ
cord-344382-vge4ho2v	113	6	-	-	HYPH
cord-344382-vge4ho2v	113	7	blind	blind	JJ
cord-344382-vge4ho2v	113	8	,	,	,
cord-344382-vge4ho2v	113	9	placebo	placebo	NN
cord-344382-vge4ho2v	113	10	-	-	HYPH
cord-344382-vge4ho2v	113	11	controlled	control	VBN
cord-344382-vge4ho2v	113	12	,	,	,
cord-344382-vge4ho2v	113	13	prospective	prospective	JJ
cord-344382-vge4ho2v	113	14	clinical	clinical	JJ
cord-344382-vge4ho2v	113	15	trial	trial	NN
cord-344382-vge4ho2v	113	16	in	in	IN
cord-344382-vge4ho2v	113	17	5	5	CD
cord-344382-vge4ho2v	113	18	ICUs	icu	NNS
cord-344382-vge4ho2v	113	19	in	in	IN
cord-344382-vge4ho2v	113	20	the	the	DT
cord-344382-vge4ho2v	113	21	USA	USA	NNP
cord-344382-vge4ho2v	113	22	and	and	CC
cord-344382-vge4ho2v	113	23	Canada	Canada	NNP
cord-344382-vge4ho2v	113	24	showed	show	VBD
cord-344382-vge4ho2v	113	25	that	that	IN
cord-344382-vge4ho2v	113	26	the	the	DT
cord-344382-vge4ho2v	113	27	intravenous	intravenous	JJ
cord-344382-vge4ho2v	113	28	administration	administration	NN
cord-344382-vge4ho2v	113	29	of	of	IN
cord-344382-vge4ho2v	113	30	NAC	NAC	NNP
cord-344382-vge4ho2v	113	31	(	(	-LRB-
cord-344382-vge4ho2v	113	32	70	70	CD
cord-344382-vge4ho2v	113	33	mg/	mg/	NN
cord-344382-vge4ho2v	113	34	kg	kg	NNP
cord-344382-vge4ho2v	113	35	body	body	NN
cord-344382-vge4ho2v	113	36	weight	weight	NN
cord-344382-vge4ho2v	113	37	)	)	-RRB-
cord-344382-vge4ho2v	113	38	,	,	,
cord-344382-vge4ho2v	113	39	every	every	DT
cord-344382-vge4ho2v	113	40	8	8	CD
cord-344382-vge4ho2v	113	41	hours	hour	NNS
cord-344382-vge4ho2v	113	42	for	for	IN
cord-344382-vge4ho2v	113	43	10	10	CD
cord-344382-vge4ho2v	113	44	days	day	NNS
cord-344382-vge4ho2v	113	45	,	,	,
cord-344382-vge4ho2v	113	46	effectively	effectively	RB
cord-344382-vge4ho2v	113	47	repleted	replete	VBD
cord-344382-vge4ho2v	113	48	GSH	GSH	NNP
cord-344382-vge4ho2v	113	49	in	in	IN
cord-344382-vge4ho2v	113	50	red	red	JJ
cord-344382-vge4ho2v	113	51	blood	blood	NN
cord-344382-vge4ho2v	113	52	cells	cell	NNS
cord-344382-vge4ho2v	113	53	,	,	,
cord-344382-vge4ho2v	113	54	decreased	decrease	VBD
cord-344382-vge4ho2v	113	55	the	the	DT
cord-344382-vge4ho2v	113	56	number	number	NN
cord-344382-vge4ho2v	113	57	of	of	IN
cord-344382-vge4ho2v	113	58	days	day	NNS
cord-344382-vge4ho2v	113	59	of	of	IN
cord-344382-vge4ho2v	113	60	acute	acute	JJ
cord-344382-vge4ho2v	113	61	lung	lung	NN
cord-344382-vge4ho2v	113	62	injury	injury	NN
cord-344382-vge4ho2v	113	63	,	,	,
cord-344382-vge4ho2v	113	64	and	and	CC
cord-344382-vge4ho2v	113	65	significantly	significantly	RB
cord-344382-vge4ho2v	113	66	increased	increase	VBD
cord-344382-vge4ho2v	113	67	the	the	DT
cord-344382-vge4ho2v	113	68	cardiac	cardiac	JJ
cord-344382-vge4ho2v	113	69	index	index	NN
cord-344382-vge4ho2v	113	70	.	.	.
cord-344382-vge4ho2v	114	1	37	37	CD
cord-344382-vge4ho2v	114	2	NAC	NAC	NNP
cord-344382-vge4ho2v	114	3	(	(	-LRB-
cord-344382-vge4ho2v	114	4	50	50	CD
cord-344382-vge4ho2v	114	5	mg	mg	NNP
cord-344382-vge4ho2v	114	6	/	/	SYM
cord-344382-vge4ho2v	114	7	kg	kg	NN
cord-344382-vge4ho2v	114	8	body	body	NN
cord-344382-vge4ho2v	114	9	weight	weight	NN
cord-344382-vge4ho2v	114	10	in	in	IN
cord-344382-vge4ho2v	114	11	250	250	CD
cord-344382-vge4ho2v	114	12	mL	mL	NNS
cord-344382-vge4ho2v	114	13	of	of	IN
cord-344382-vge4ho2v	114	14	5	5	CD
cord-344382-vge4ho2v	114	15	%	%	NN
cord-344382-vge4ho2v	114	16	dextrose	dextrose	NN
cord-344382-vge4ho2v	114	17	for	for	IN
cord-344382-vge4ho2v	114	18	6	6	CD
cord-344382-vge4ho2v	114	19	days	day	NNS
cord-344382-vge4ho2v	114	20	)	)	-RRB-
cord-344382-vge4ho2v	114	21	protected	protect	VBD
cord-344382-vge4ho2v	114	22	the	the	DT
cord-344382-vge4ho2v	114	23	lungs	lung	NNS
cord-344382-vge4ho2v	114	24	of	of	IN
cord-344382-vge4ho2v	114	25	ARDS	ARDS	NNP
cord-344382-vge4ho2v	114	26	patients	patient	NNS
cord-344382-vge4ho2v	114	27	,	,	,
cord-344382-vge4ho2v	114	28	as	as	IN
cord-344382-vge4ho2v	114	29	evaluated	evaluate	VBN
cord-344382-vge4ho2v	114	30	by	by	IN
cord-344382-vge4ho2v	114	31	measuring	measure	VBG
cord-344382-vge4ho2v	114	32	the	the	DT
cord-344382-vge4ho2v	114	33	expired	expire	VBN
cord-344382-vge4ho2v	114	34	ethane	ethane	NN
cord-344382-vge4ho2v	114	35	and	and	CC
cord-344382-vge4ho2v	114	36	malondialdehyde	malondialdehyde	NNP
cord-344382-vge4ho2v	114	37	(	(	-LRB-
cord-344382-vge4ho2v	114	38	MDA	MDA	NNP
cord-344382-vge4ho2v	114	39	)	)	-RRB-
cord-344382-vge4ho2v	114	40	as	as	RB
cord-344382-vge4ho2v	114	41	well	well	RB
cord-344382-vge4ho2v	114	42	as	as	IN
cord-344382-vge4ho2v	114	43	GSSG	GSSG	NNP
cord-344382-vge4ho2v	114	44	and	and	CC
cord-344382-vge4ho2v	114	45	GSH	GSH	NNP
cord-344382-vge4ho2v	114	46	in	in	IN
cord-344382-vge4ho2v	114	47	the	the	DT
cord-344382-vge4ho2v	114	48	epithelial	epithelial	JJ
cord-344382-vge4ho2v	114	49	lining	lining	NN
cord-344382-vge4ho2v	114	50	fluid	fluid	NN
cord-344382-vge4ho2v	114	51	.	.	.
cord-344382-vge4ho2v	115	1	38	38	CD
cord-344382-vge4ho2v	116	1	In	in	IN
cord-344382-vge4ho2v	116	2	another	another	DT
cord-344382-vge4ho2v	116	3	study	study	NN
cord-344382-vge4ho2v	116	4	,	,	,
cord-344382-vge4ho2v	116	5	patients	patient	NNS
cord-344382-vge4ho2v	116	6	hospitalized	hospitalize	VBN
cord-344382-vge4ho2v	116	7	in	in	IN
cord-344382-vge4ho2v	116	8	ICU	ICU	NNP
cord-344382-vge4ho2v	116	9	who	who	WP
cord-344382-vge4ho2v	116	10	received	receive	VBD
cord-344382-vge4ho2v	116	11	NAC	NAC	NNP
cord-344382-vge4ho2v	116	12	(	(	-LRB-
cord-344382-vge4ho2v	116	13	150	150	CD
cord-344382-vge4ho2v	116	14	mg	mg	NNP
cord-344382-vge4ho2v	116	15	/	/	SYM
cord-344382-vge4ho2v	116	16	kg	kg	NN
cord-344382-vge4ho2v	116	17	body	body	NN
cord-344382-vge4ho2v	116	18	weight	weight	NN
cord-344382-vge4ho2v	116	19	on	on	IN
cord-344382-vge4ho2v	116	20	the	the	DT
cord-344382-vge4ho2v	116	21	first	first	JJ
cord-344382-vge4ho2v	116	22	day	day	NN
cord-344382-vge4ho2v	116	23	,	,	,
cord-344382-vge4ho2v	116	24	followed	follow	VBN
cord-344382-vge4ho2v	116	25	by	by	IN
cord-344382-vge4ho2v	116	26	50	50	CD
cord-344382-vge4ho2v	116	27	mg	mg	NNP
cord-344382-vge4ho2v	116	28	/	/	SYM
cord-344382-vge4ho2v	116	29	kg	kg	NN
cord-344382-vge4ho2v	116	30	for	for	IN
cord-344382-vge4ho2v	116	31	3	3	CD
cord-344382-vge4ho2v	116	32	days	day	NNS
cord-344382-vge4ho2v	116	33	)	)	-RRB-
cord-344382-vge4ho2v	116	34	had	have	VBD
cord-344382-vge4ho2v	116	35	a	a	DT
cord-344382-vge4ho2v	116	36	better	well	JJR
cord-344382-vge4ho2v	116	37	clinical	clinical	JJ
cord-344382-vge4ho2v	116	38	outcome	outcome	NN
cord-344382-vge4ho2v	116	39	as	as	IN
cord-344382-vge4ho2v	116	40	compared	compare	VBN
cord-344382-vge4ho2v	116	41	with	with	IN
cord-344382-vge4ho2v	116	42	patients	patient	NNS
cord-344382-vge4ho2v	116	43	in	in	IN
cord-344382-vge4ho2v	116	44	the	the	DT
cord-344382-vge4ho2v	116	45	placebo	placebo	NN
cord-344382-vge4ho2v	116	46	group	group	NN
cord-344382-vge4ho2v	116	47	.	.	.
cord-344382-vge4ho2v	117	1	Moreover	moreover	RB
cord-344382-vge4ho2v	117	2	,	,	,
cord-344382-vge4ho2v	117	3	NAC	NAC	NNP
cord-344382-vge4ho2v	117	4	increased	increase	VBD
cord-344382-vge4ho2v	117	5	extracellular	extracellular	JJ
cord-344382-vge4ho2v	117	6	total	total	JJ
cord-344382-vge4ho2v	117	7	antioxidant	antioxidant	JJ
cord-344382-vge4ho2v	117	8	power	power	NN
cord-344382-vge4ho2v	117	9	and	and	CC
cord-344382-vge4ho2v	117	10	total	total	JJ
cord-344382-vge4ho2v	117	11	thiol	thiol	NN
cord-344382-vge4ho2v	117	12	molecules	molecule	NNS
cord-344382-vge4ho2v	117	13	.	.	.
cord-344382-vge4ho2v	118	1	39	39	CD
cord-344382-vge4ho2v	119	1	A	a	DT
cord-344382-vge4ho2v	119	2	further	further	JJ
cord-344382-vge4ho2v	119	3	mechanism	mechanism	NN
cord-344382-vge4ho2v	119	4	is	be	VBZ
cord-344382-vge4ho2v	119	5	that	that	IN
cord-344382-vge4ho2v	119	6	NAC	NAC	NNP
cord-344382-vge4ho2v	119	7	further	further	RB
cord-344382-vge4ho2v	119	8	enhances	enhance	VBZ
cord-344382-vge4ho2v	119	9	the	the	DT
cord-344382-vge4ho2v	119	10	stimulation	stimulation	NN
cord-344382-vge4ho2v	119	11	of	of	IN
cord-344382-vge4ho2v	119	12	nuclear	nuclear	JJ
cord-344382-vge4ho2v	119	13	factor	factor	NN
cord-344382-vge4ho2v	119	14	erythroid	erythroid	NN
cord-344382-vge4ho2v	119	15	2-related	2-related	CD
cord-344382-vge4ho2v	119	16	factor	factor	NN
cord-344382-vge4ho2v	119	17	2	2	CD
cord-344382-vge4ho2v	119	18	(	(	-LRB-
cord-344382-vge4ho2v	119	19	Nrf2	Nrf2	NNP
cord-344382-vge4ho2v	119	20	)	)	-RRB-
cord-344382-vge4ho2v	119	21	by	by	IN
cord-344382-vge4ho2v	119	22	oxidative	oxidative	JJ
cord-344382-vge4ho2v	119	23	stress	stress	NN
cord-344382-vge4ho2v	119	24	,	,	,
cord-344382-vge4ho2v	119	25	40	40	CD
cord-344382-vge4ho2v	119	26	which	which	WDT
cord-344382-vge4ho2v	119	27	favors	favor	VBZ
cord-344382-vge4ho2v	119	28	transcription	transcription	NN
cord-344382-vge4ho2v	119	29	of	of	IN
cord-344382-vge4ho2v	119	30	phase	phase	NN
cord-344382-vge4ho2v	119	31	II	II	NNP
cord-344382-vge4ho2v	119	32	enzyme	enzyme	NN
cord-344382-vge4ho2v	119	33	genes	gene	NNS
cord-344382-vge4ho2v	119	34	and	and	CC
cord-344382-vge4ho2v	119	35	downregulates	downregulate	VBZ
cord-344382-vge4ho2v	119	36	inflammation	inflammation	NN
cord-344382-vge4ho2v	119	37	.	.	.
cord-344382-vge4ho2v	120	1	In	in	IN
cord-344382-vge4ho2v	120	2	fact	fact	NN
cord-344382-vge4ho2v	120	3	,	,	,
cord-344382-vge4ho2v	120	4	Nrf-2	Nrf-2	NNP
cord-344382-vge4ho2v	120	5	is	be	VBZ
cord-344382-vge4ho2v	120	6	essential	essential	JJ
cord-344382-vge4ho2v	120	7	for	for	IN
cord-344382-vge4ho2v	120	8	the	the	DT
cord-344382-vge4ho2v	120	9	antioxidant	antioxidant	JJ
cord-344382-vge4ho2v	120	10	responsive	responsive	JJ
cord-344382-vge4ho2v	120	11	element	element	NN
cord-344382-vge4ho2v	120	12	(	(	-LRB-
cord-344382-vge4ho2v	120	13	ARE)-mediated	are)-mediated	JJ
cord-344382-vge4ho2v	120	14	induction	induction	NN
cord-344382-vge4ho2v	120	15	of	of	IN
cord-344382-vge4ho2v	120	16	endogenous	endogenous	JJ
cord-344382-vge4ho2v	120	17	antioxidant	antioxidant	NN
cord-344382-vge4ho2v	120	18	enzymes	enzyme	NNS
cord-344382-vge4ho2v	120	19	such	such	JJ
cord-344382-vge4ho2v	120	20	as	as	IN
cord-344382-vge4ho2v	120	21	heme	heme	NN
cord-344382-vge4ho2v	120	22	oxygenase	oxygenase	NN
cord-344382-vge4ho2v	120	23	1	1	CD
cord-344382-vge4ho2v	120	24	(	(	-LRB-
cord-344382-vge4ho2v	120	25	HO-1	HO-1	NNP
cord-344382-vge4ho2v	120	26	)	)	-RRB-
cord-344382-vge4ho2v	120	27	,	,	,
cord-344382-vge4ho2v	120	28	NAD(P)H	NAD(P)H	NNP
cord-344382-vge4ho2v	120	29	dehydrogenase	dehydrogenase	NN
cord-344382-vge4ho2v	120	30	[	[	-LRB-
cord-344382-vge4ho2v	120	31	quinone	quinone	NN
cord-344382-vge4ho2v	120	32	]	]	-RRB-
cord-344382-vge4ho2v	120	33	1	1	CD
cord-344382-vge4ho2v	120	34	(	(	-LRB-
cord-344382-vge4ho2v	120	35	NQO-1	NQO-1	NNP
cord-344382-vge4ho2v	120	36	)	)	-RRB-
cord-344382-vge4ho2v	120	37	,	,	,
cord-344382-vge4ho2v	120	38	and	and	CC
cord-344382-vge4ho2v	120	39	GCL	GCL	NNP
cord-344382-vge4ho2v	120	40	.	.	.
cord-344382-vge4ho2v	121	1	41	41	CD
cord-344382-vge4ho2v	122	1	Interestingly	interestingly	RB
cord-344382-vge4ho2v	122	2	,	,	,
cord-344382-vge4ho2v	122	3	it	-PRON-	PRP
cord-344382-vge4ho2v	122	4	has	have	VBZ
cord-344382-vge4ho2v	122	5	been	be	VBN
cord-344382-vge4ho2v	122	6	proposed	propose	VBN
cord-344382-vge4ho2v	122	7	that	that	IN
cord-344382-vge4ho2v	122	8	targeting	target	VBG
cord-344382-vge4ho2v	122	9	the	the	DT
cord-344382-vge4ho2v	122	10	heme	heme	JJ
cord-344382-vge4ho2v	122	11	-	-	HYPH
cord-344382-vge4ho2v	122	12	heme	heme	JJ
cord-344382-vge4ho2v	122	13	oxygenase	oxygenase	NN
cord-344382-vge4ho2v	122	14	system	system	NN
cord-344382-vge4ho2v	122	15	may	may	MD
cord-344382-vge4ho2v	122	16	prevent	prevent	VB
cord-344382-vge4ho2v	122	17	severe	severe	JJ
cord-344382-vge4ho2v	122	18	complications	complication	NNS
cord-344382-vge4ho2v	122	19	following	follow	VBG
cord-344382-vge4ho2v	122	20	COVID-19	covid-19	JJ
cord-344382-vge4ho2v	122	21	infection	infection	NN
cord-344382-vge4ho2v	122	22	.	.	.
cord-344382-vge4ho2v	123	1	42	42	CD
cord-344382-vge4ho2v	124	1	In	in	IN
cord-344382-vge4ho2v	124	2	parallel	parallel	NN
cord-344382-vge4ho2v	124	3	,	,	,
cord-344382-vge4ho2v	124	4	NAC	NAC	NNP
cord-344382-vge4ho2v	124	5	inhibits	inhibit	VBZ
cord-344382-vge4ho2v	124	6	the	the	DT
cord-344382-vge4ho2v	124	7	oxidative	oxidative	JJ
cord-344382-vge4ho2v	124	8	stress	stress	NN
cord-344382-vge4ho2v	124	9	-	-	HYPH
cord-344382-vge4ho2v	124	10	mediated	mediate	VBN
cord-344382-vge4ho2v	124	11	activation	activation	NN
cord-344382-vge4ho2v	124	12	of	of	IN
cord-344382-vge4ho2v	124	13	nuclear	nuclear	JJ
cord-344382-vge4ho2v	124	14	factor	factor	NN
cord-344382-vge4ho2v	124	15	kappa	kappa	NN
cord-344382-vge4ho2v	124	16	-	-	HYPH
cord-344382-vge4ho2v	124	17	lightchain	lightchain	NN
cord-344382-vge4ho2v	124	18	-	-	HYPH
cord-344382-vge4ho2v	124	19	enhancer	enhancer	NN
cord-344382-vge4ho2v	124	20	of	of	IN
cord-344382-vge4ho2v	124	21	activated	activate	VBN
cord-344382-vge4ho2v	124	22	B	b	NN
cord-344382-vge4ho2v	124	23	cells	cell	NNS
cord-344382-vge4ho2v	124	24	(	(	-LRB-
cord-344382-vge4ho2v	124	25	NFκB	NFκB	NNP
cord-344382-vge4ho2v	124	26	)	)	-RRB-
cord-344382-vge4ho2v	124	27	and	and	CC
cord-344382-vge4ho2v	124	28	biochemical	biochemical	JJ
cord-344382-vge4ho2v	124	29	pathways	pathway	NNS
cord-344382-vge4ho2v	124	30	upregulating	upregulate	VBG
cord-344382-vge4ho2v	124	31	pro	pro	JJ
cord-344382-vge4ho2v	124	32	-	-	JJ
cord-344382-vge4ho2v	124	33	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	124	34	genes	gene	NNS
cord-344382-vge4ho2v	124	35	.	.	.
cord-344382-vge4ho2v	125	1	14	14	CD
cord-344382-vge4ho2v	125	2	NAC	NAC	NNP
cord-344382-vge4ho2v	125	3	also	also	RB
cord-344382-vge4ho2v	125	4	reduced	reduce	VBD
cord-344382-vge4ho2v	125	5	the	the	DT
cord-344382-vge4ho2v	125	6	intracellular	intracellular	JJ
cord-344382-vge4ho2v	125	7	hydrogen	hydrogen	NN
cord-344382-vge4ho2v	125	8	peroxide	peroxide	NN
cord-344382-vge4ho2v	125	9	concentration	concentration	NN
cord-344382-vge4ho2v	125	10	and	and	CC
cord-344382-vge4ho2v	125	11	restored	restore	VBD
cord-344382-vge4ho2v	125	12	the	the	DT
cord-344382-vge4ho2v	125	13	intracellular	intracellular	JJ
cord-344382-vge4ho2v	125	14	total	total	JJ
cord-344382-vge4ho2v	125	15	thiol	thiol	NN
cord-344382-vge4ho2v	125	16	contents	content	NNS
cord-344382-vge4ho2v	125	17	by	by	IN
cord-344382-vge4ho2v	125	18	inhibiting	inhibit	VBG
cord-344382-vge4ho2v	125	19	NFκB	nfκb	JJ
cord-344382-vge4ho2v	125	20	translocation	translocation	NN
cord-344382-vge4ho2v	125	21	to	to	IN
cord-344382-vge4ho2v	125	22	the	the	DT
cord-344382-vge4ho2v	125	23	cellular	cellular	JJ
cord-344382-vge4ho2v	125	24	nucleus	nucleus	NN
cord-344382-vge4ho2v	125	25	and	and	CC
cord-344382-vge4ho2v	125	26	phosphorylation	phosphorylation	NN
cord-344382-vge4ho2v	125	27	of	of	IN
cord-344382-vge4ho2v	125	28	p38	p38	CD
cord-344382-vge4ho2v	125	29	mitogen	mitogen	NN
cord-344382-vge4ho2v	125	30	-	-	HYPH
cord-344382-vge4ho2v	125	31	activated	activate	VBN
cord-344382-vge4ho2v	125	32	protein	protein	NN
cord-344382-vge4ho2v	125	33	kinase	kinase	NN
cord-344382-vge4ho2v	125	34	(	(	-LRB-
cord-344382-vge4ho2v	125	35	MAPK	MAPK	NNP
cord-344382-vge4ho2v	125	36	p38	p38	CD
cord-344382-vge4ho2v	125	37	)	)	-RRB-
cord-344382-vge4ho2v	125	38	.	.	.
cord-344382-vge4ho2v	126	1	43	43	CD
cord-344382-vge4ho2v	127	1	In	in	IN
cord-344382-vge4ho2v	127	2	influenza	influenza	NN
cord-344382-vge4ho2v	127	3	infection	infection	NN
cord-344382-vge4ho2v	127	4	,	,	,
cord-344382-vge4ho2v	127	5	NAC	NAC	NNP
cord-344382-vge4ho2v	127	6	inhibits	inhibit	VBZ
cord-344382-vge4ho2v	127	7	the	the	DT
cord-344382-vge4ho2v	127	8	induction	induction	NN
cord-344382-vge4ho2v	127	9	of	of	IN
cord-344382-vge4ho2v	127	10	pro	pro	JJ
cord-344382-vge4ho2v	127	11	-	-	JJ
cord-344382-vge4ho2v	127	12	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	127	13	cytokine	cytokine	NN
cord-344382-vge4ho2v	127	14	response	response	NN
cord-344382-vge4ho2v	127	15	through	through	IN
cord-344382-vge4ho2v	127	16	endosomal	endosomal	NNP
cord-344382-vge4ho2v	127	17	tolllike	tolllike	NNP
cord-344382-vge4ho2v	127	18	receptor	receptor	NNP
cord-344382-vge4ho2v	127	19	3	3	CD
cord-344382-vge4ho2v	127	20	/	/	SYM
cord-344382-vge4ho2v	127	21	hemagglutinin	hemagglutinin	NN
cord-344382-vge4ho2v	128	1	(	(	-LRB-
cord-344382-vge4ho2v	128	2	TLR3	TLR3	NNP
cord-344382-vge4ho2v	128	3	/	/	SYM
cord-344382-vge4ho2v	128	4	HA)-induced	ha)-induced	CD
cord-344382-vge4ho2v	128	5	,	,	,
cord-344382-vge4ho2v	128	6	ROSdependent	rosdependent	JJ
cord-344382-vge4ho2v	128	7	NFκB	NFκB	NNP
cord-344382-vge4ho2v	128	8	activation	activation	NN
cord-344382-vge4ho2v	128	9	.	.	.
cord-344382-vge4ho2v	129	1	44	44	CD
cord-344382-vge4ho2v	130	1	Furthermore	furthermore	RB
cord-344382-vge4ho2v	130	2	,	,	,
cord-344382-vge4ho2v	130	3	NAC	NAC	NNP
cord-344382-vge4ho2v	130	4	has	have	VBZ
cord-344382-vge4ho2v	130	5	anti	anti	JJ
cord-344382-vge4ho2v	130	6	-	-	JJ
cord-344382-vge4ho2v	130	7	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	130	8	activity	activity	NN
cord-344382-vge4ho2v	130	9	independently	independently	RB
cord-344382-vge4ho2v	130	10	of	of	IN
cord-344382-vge4ho2v	130	11	its	-PRON-	PRP$
cord-344382-vge4ho2v	130	12	antioxidant	antioxidant	JJ
cord-344382-vge4ho2v	130	13	activity	activity	NN
cord-344382-vge4ho2v	130	14	,	,	,
cord-344382-vge4ho2v	130	15	as	as	IN
cord-344382-vge4ho2v	130	16	shown	show	VBN
cord-344382-vge4ho2v	130	17	by	by	IN
cord-344382-vge4ho2v	130	18	the	the	DT
cord-344382-vge4ho2v	130	19	finding	finding	NN
cord-344382-vge4ho2v	130	20	that	that	IN
cord-344382-vge4ho2v	130	21	it	-PRON-	PRP
cord-344382-vge4ho2v	130	22	inhibited	inhibit	VBD
cord-344382-vge4ho2v	130	23	the	the	DT
cord-344382-vge4ho2v	130	24	LPS	LPS	NNP
cord-344382-vge4ho2v	130	25	-	-	HYPH
cord-344382-vge4ho2v	130	26	mediated	mediate	VBN
cord-344382-vge4ho2v	130	27	neurogenic	neurogenic	JJ
cord-344382-vge4ho2v	130	28	inflammation	inflammation	NN
cord-344382-vge4ho2v	130	29	by	by	IN
cord-344382-vge4ho2v	130	30	counteracting	counteract	VBG
cord-344382-vge4ho2v	130	31	the	the	DT
cord-344382-vge4ho2v	130	32	release	release	NN
cord-344382-vge4ho2v	130	33	of	of	IN
cord-344382-vge4ho2v	130	34	Na	Na	NNP
cord-344382-vge4ho2v	130	35	,	,	,
cord-344382-vge4ho2v	130	36	K	K	NNP
cord-344382-vge4ho2v	130	37	-	-	HYPH
cord-344382-vge4ho2v	130	38	ATPase	ATPase	NNP
cord-344382-vge4ho2v	130	39	(	(	-LRB-
cord-344382-vge4ho2v	130	40	NKA	NKA	NNP
cord-344382-vge4ho2v	130	41	)	)	-RRB-
cord-344382-vge4ho2v	130	42	,	,	,
cord-344382-vge4ho2v	130	43	a	a	DT
cord-344382-vge4ho2v	130	44	marker	marker	NN
cord-344382-vge4ho2v	130	45	for	for	IN
cord-344382-vge4ho2v	130	46	cell	cell	NN
cord-344382-vge4ho2v	130	47	necrosis	necrosis	NN
cord-344382-vge4ho2v	130	48	,	,	,
cord-344382-vge4ho2v	130	49	which	which	WDT
cord-344382-vge4ho2v	130	50	could	could	MD
cord-344382-vge4ho2v	130	51	explain	explain	VB
cord-344382-vge4ho2v	130	52	the	the	DT
cord-344382-vge4ho2v	130	53	fall	fall	NN
cord-344382-vge4ho2v	130	54	in	in	IN
cord-344382-vge4ho2v	130	55	IL-6	IL-6	NNP
cord-344382-vge4ho2v	130	56	with	with	IN
cord-344382-vge4ho2v	130	57	NAC	NAC	NNP
cord-344382-vge4ho2v	130	58	.	.	.
cord-344382-vge4ho2v	131	1	45	45	CD
cord-344382-vge4ho2v	132	1	A	a	DT
cord-344382-vge4ho2v	132	2	multicenter	multicenter	NN
cord-344382-vge4ho2v	132	3	,	,	,
cord-344382-vge4ho2v	132	4	randomized	randomized	JJ
cord-344382-vge4ho2v	132	5	,	,	,
cord-344382-vge4ho2v	132	6	placebo	placebo	NN
cord-344382-vge4ho2v	132	7	-	-	HYPH
cord-344382-vge4ho2v	132	8	controlled	control	VBN
cord-344382-vge4ho2v	132	9	trial	trial	NN
cord-344382-vge4ho2v	132	10	,	,	,
cord-344382-vge4ho2v	132	11	sequentially	sequentially	RB
cord-344382-vge4ho2v	132	12	testing	test	VBG
cord-344382-vge4ho2v	132	13	early	early	JJ
cord-344382-vge4ho2v	132	14	use	use	NN
cord-344382-vge4ho2v	132	15	of	of	IN
cord-344382-vge4ho2v	132	16	intravenous	intravenous	JJ
cord-344382-vge4ho2v	132	17	NAC	NAC	NNP
cord-344382-vge4ho2v	132	18	,	,	,
cord-344382-vge4ho2v	132	19	followed	follow	VBN
cord-344382-vge4ho2v	132	20	by	by	IN
cord-344382-vge4ho2v	132	21	oral	oral	JJ
cord-344382-vge4ho2v	132	22	ramipril	ramipril	NN
cord-344382-vge4ho2v	132	23	for	for	IN
cord-344382-vge4ho2v	132	24	12	12	CD
cord-344382-vge4ho2v	132	25	weeks	week	NNS
cord-344382-vge4ho2v	132	26	,	,	,
cord-344382-vge4ho2v	132	27	is	be	VBZ
cord-344382-vge4ho2v	132	28	based	base	VBN
cord-344382-vge4ho2v	132	29	on	on	IN
cord-344382-vge4ho2v	132	30	the	the	DT
cord-344382-vge4ho2v	132	31	rationale	rationale	NN
cord-344382-vge4ho2v	132	32	that	that	IN
cord-344382-vge4ho2v	132	33	these	these	DT
cord-344382-vge4ho2v	132	34	agents	agent	NNS
cord-344382-vge4ho2v	132	35	have	have	VBP
cord-344382-vge4ho2v	132	36	the	the	DT
cord-344382-vge4ho2v	132	37	ability	ability	NN
cord-344382-vge4ho2v	132	38	to	to	TO
cord-344382-vge4ho2v	132	39	limit	limit	VB
cord-344382-vge4ho2v	132	40	nitrosative	nitrosative	JJ
cord-344382-vge4ho2v	132	41	stress	stress	NN
cord-344382-vge4ho2v	132	42	and	and	CC
cord-344382-vge4ho2v	132	43	expression	expression	NN
cord-344382-vge4ho2v	132	44	of	of	IN
cord-344382-vge4ho2v	132	45	the	the	DT
cord-344382-vge4ho2v	132	46	inflammasome	inflammasome	NN
cord-344382-vge4ho2v	132	47	activator	activator	NN
cord-344382-vge4ho2v	132	48	thioredoxin	thioredoxin	NNP
cord-344382-vge4ho2v	132	49	interacting	interact	VBG
cord-344382-vge4ho2v	132	50	protein	protein	NN
cord-344382-vge4ho2v	132	51	(	(	-LRB-
cord-344382-vge4ho2v	132	52	TXNIP	TXNIP	NNP
cord-344382-vge4ho2v	132	53	)	)	-RRB-
cord-344382-vge4ho2v	132	54	.	.	.
cord-344382-vge4ho2v	133	1	46	46	CD
cord-344382-vge4ho2v	133	2	 	 	_SP
cord-344382-vge4ho2v	134	1	NAC	NAC	NNP
cord-344382-vge4ho2v	134	2	has	have	VBZ
cord-344382-vge4ho2v	134	3	been	be	VBN
cord-344382-vge4ho2v	134	4	demonstrated	demonstrate	VBN
cord-344382-vge4ho2v	134	5	to	to	TO
cord-344382-vge4ho2v	134	6	attenuate	attenuate	VB
cord-344382-vge4ho2v	134	7	the	the	DT
cord-344382-vge4ho2v	134	8	incidence	incidence	NN
cord-344382-vge4ho2v	134	9	and	and	CC
cord-344382-vge4ho2v	134	10	severity	severity	NN
cord-344382-vge4ho2v	134	11	of	of	IN
cord-344382-vge4ho2v	134	12	influenza	influenza	NN
cord-344382-vge4ho2v	134	13	and	and	CC
cord-344382-vge4ho2v	134	14	influenza	influenza	NN
cord-344382-vge4ho2v	134	15	-	-	HYPH
cord-344382-vge4ho2v	134	16	like	like	JJ
cord-344382-vge4ho2v	134	17	illnesses	illness	NNS
cord-344382-vge4ho2v	134	18	.	.	.
cord-344382-vge4ho2v	135	1	It	-PRON-	PRP
cord-344382-vge4ho2v	135	2	was	be	VBD
cord-344382-vge4ho2v	135	3	tested	test	VBN
cord-344382-vge4ho2v	135	4	in	in	IN
cord-344382-vge4ho2v	135	5	a	a	DT
cord-344382-vge4ho2v	135	6	double	double	JJ
cord-344382-vge4ho2v	135	7	-	-	HYPH
cord-344382-vge4ho2v	135	8	blind	blind	JJ
cord-344382-vge4ho2v	135	9	trial	trial	NN
cord-344382-vge4ho2v	135	10	,	,	,
cord-344382-vge4ho2v	135	11	involving	involve	VBG
cord-344382-vge4ho2v	135	12	20	20	CD
cord-344382-vge4ho2v	135	13	Italian	Italian	NNP
cord-344382-vge4ho2v	135	14	Centers	Centers	NNPS
cord-344382-vge4ho2v	135	15	,	,	,
cord-344382-vge4ho2v	135	16	which	which	WDT
cord-344382-vge4ho2v	135	17	enrolled	enrol	VBD
cord-344382-vge4ho2v	135	18	262	262	CD
cord-344382-vge4ho2v	135	19	subjects	subject	NNS
cord-344382-vge4ho2v	135	20	of	of	IN
cord-344382-vge4ho2v	135	21	both	both	DT
cord-344382-vge4ho2v	135	22	sexes	sex	NNS
cord-344382-vge4ho2v	135	23	randomized	randomize	VBN
cord-344382-vge4ho2v	135	24	to	to	TO
cord-344382-vge4ho2v	135	25	receive	receive	VB
cord-344382-vge4ho2v	135	26	either	either	CC
cord-344382-vge4ho2v	135	27	placebo	placebo	NN
cord-344382-vge4ho2v	135	28	or	or	CC
cord-344382-vge4ho2v	135	29	NAC	NAC	NNP
cord-344382-vge4ho2v	135	30	tablets	tablet	NNS
cord-344382-vge4ho2v	135	31	(	(	-LRB-
cord-344382-vge4ho2v	135	32	600	600	CD
cord-344382-vge4ho2v	135	33	mg	mg	NNP
cord-344382-vge4ho2v	135	34	)	)	-RRB-
cord-344382-vge4ho2v	135	35	twice	twice	RB
cord-344382-vge4ho2v	135	36	daily	daily	RB
cord-344382-vge4ho2v	135	37	for	for	IN
cord-344382-vge4ho2v	135	38	6	6	CD
cord-344382-vge4ho2v	135	39	months	month	NNS
cord-344382-vge4ho2v	135	40	.	.	.
cord-344382-vge4ho2v	136	1	Both	both	DT
cord-344382-vge4ho2v	136	2	local	local	JJ
cord-344382-vge4ho2v	136	3	and	and	CC
cord-344382-vge4ho2v	136	4	systemic	systemic	JJ
cord-344382-vge4ho2v	136	5	symptoms	symptom	NNS
cord-344382-vge4ho2v	136	6	were	be	VBD
cord-344382-vge4ho2v	136	7	sharply	sharply	RB
cord-344382-vge4ho2v	136	8	and	and	CC
cord-344382-vge4ho2v	136	9	significantly	significantly	RB
cord-344382-vge4ho2v	136	10	reduced	reduce	VBN
cord-344382-vge4ho2v	136	11	in	in	IN
cord-344382-vge4ho2v	136	12	the	the	DT
cord-344382-vge4ho2v	136	13	NAC	NAC	NNP
cord-344382-vge4ho2v	136	14	group	group	NN
cord-344382-vge4ho2v	136	15	.	.	.
cord-344382-vge4ho2v	137	1	Moreover	moreover	RB
cord-344382-vge4ho2v	137	2	,	,	,
cord-344382-vge4ho2v	137	3	only	only	RB
cord-344382-vge4ho2v	137	4	25	25	CD
cord-344382-vge4ho2v	137	5	%	%	NN
cord-344382-vge4ho2v	137	6	of	of	IN
cord-344382-vge4ho2v	137	7	A	A	NNP
cord-344382-vge4ho2v	137	8	/	/	SYM
cord-344382-vge4ho2v	137	9	H1N1	H1N1	NNP
cord-344382-vge4ho2v	137	10	influenza	influenza	NN
cord-344382-vge4ho2v	137	11	virus	virus	NN
cord-344382-vge4ho2v	137	12	-	-	HYPH
cord-344382-vge4ho2v	137	13	infected	infect	VBN
cord-344382-vge4ho2v	137	14	subjects	subject	NNS
cord-344382-vge4ho2v	137	15	under	under	IN
cord-344382-vge4ho2v	137	16	NAC	NAC	NNP
cord-344382-vge4ho2v	137	17	treatment	treatment	NN
cord-344382-vge4ho2v	137	18	developed	develop	VBD
cord-344382-vge4ho2v	137	19	a	a	DT
cord-344382-vge4ho2v	137	20	symptomatic	symptomatic	JJ
cord-344382-vge4ho2v	137	21	form	form	NN
cord-344382-vge4ho2v	137	22	vs	vs	IN
cord-344382-vge4ho2v	137	23	79	79	CD
cord-344382-vge4ho2v	137	24	%	%	NN
cord-344382-vge4ho2v	137	25	in	in	IN
cord-344382-vge4ho2v	137	26	the	the	DT
cord-344382-vge4ho2v	137	27	placebo	placebo	NN
cord-344382-vge4ho2v	137	28	group	group	NN
cord-344382-vge4ho2v	137	29	.	.	.
cord-344382-vge4ho2v	138	1	47	47	CD
cord-344382-vge4ho2v	138	2	Infection	infection	NN
cord-344382-vge4ho2v	138	3	by	by	IN
cord-344382-vge4ho2v	138	4	RNA	RNA	NNP
cord-344382-vge4ho2v	138	5	viruses	virus	NNS
cord-344382-vge4ho2v	138	6	induces	induce	VBZ
cord-344382-vge4ho2v	138	7	oxidative	oxidative	JJ
cord-344382-vge4ho2v	138	8	stress	stress	NN
cord-344382-vge4ho2v	138	9	in	in	IN
cord-344382-vge4ho2v	138	10	host	host	NN
cord-344382-vge4ho2v	138	11	cells	cell	NNS
cord-344382-vge4ho2v	138	12	,	,	,
cord-344382-vge4ho2v	138	13	and	and	CC
cord-344382-vge4ho2v	138	14	growing	grow	VBG
cord-344382-vge4ho2v	138	15	evidence	evidence	NN
cord-344382-vge4ho2v	138	16	indicates	indicate	VBZ
cord-344382-vge4ho2v	138	17	that	that	IN
cord-344382-vge4ho2v	138	18	viral	viral	JJ
cord-344382-vge4ho2v	138	19	replication	replication	NN
cord-344382-vge4ho2v	138	20	is	be	VBZ
cord-344382-vge4ho2v	138	21	regulated	regulate	VBN
cord-344382-vge4ho2v	138	22	by	by	IN
cord-344382-vge4ho2v	138	23	the	the	DT
cord-344382-vge4ho2v	138	24	redox	redox	JJ
cord-344382-vge4ho2v	138	25	state	state	NN
cord-344382-vge4ho2v	138	26	of	of	IN
cord-344382-vge4ho2v	138	27	the	the	DT
cord-344382-vge4ho2v	138	28	host	host	NN
cord-344382-vge4ho2v	138	29	cell	cell	NN
cord-344382-vge4ho2v	138	30	and	and	CC
cord-344382-vge4ho2v	138	31	that	that	IN
cord-344382-vge4ho2v	138	32	the	the	DT
cord-344382-vge4ho2v	138	33	GSH	GSH	NNP
cord-344382-vge4ho2v	138	34	content	content	NN
cord-344382-vge4ho2v	138	35	contributes	contribute	VBZ
cord-344382-vge4ho2v	138	36	to	to	TO
cord-344382-vge4ho2v	138	37	downregulate	downregulate	VB
cord-344382-vge4ho2v	138	38	influenza	influenza	NN
cord-344382-vge4ho2v	138	39	virus	virus	NN
cord-344382-vge4ho2v	138	40	replication	replication	NN
cord-344382-vge4ho2v	138	41	.	.	.
cord-344382-vge4ho2v	139	1	48	48	CD
cord-344382-vge4ho2v	140	1	An	an	DT
cord-344382-vge4ho2v	140	2	experimental	experimental	JJ
cord-344382-vge4ho2v	140	3	study	study	NN
cord-344382-vge4ho2v	140	4	showed	show	VBD
cord-344382-vge4ho2v	140	5	that	that	IN
cord-344382-vge4ho2v	140	6	GSH	GSH	NNP
cord-344382-vge4ho2v	140	7	decreased	decrease	VBD
cord-344382-vge4ho2v	140	8	the	the	DT
cord-344382-vge4ho2v	140	9	production	production	NN
cord-344382-vge4ho2v	140	10	of	of	IN
cord-344382-vge4ho2v	140	11	influenza	influenza	NN
cord-344382-vge4ho2v	140	12	virus	virus	NN
cord-344382-vge4ho2v	140	13	particles	particle	NNS
cord-344382-vge4ho2v	140	14	in	in	IN
cord-344382-vge4ho2v	140	15	canine	canine	JJ
cord-344382-vge4ho2v	140	16	kidney	kidney	NN
cord-344382-vge4ho2v	140	17	cells	cell	NNS
cord-344382-vge4ho2v	140	18	or	or	CC
cord-344382-vge4ho2v	140	19	human	human	JJ
cord-344382-vge4ho2v	140	20	small	small	JJ
cord-344382-vge4ho2v	140	21	airway	airway	NN
cord-344382-vge4ho2v	140	22	epithelial	epithelial	JJ
cord-344382-vge4ho2v	140	23	cells	cell	NNS
cord-344382-vge4ho2v	140	24	,	,	,
cord-344382-vge4ho2v	140	25	where	where	WRB
cord-344382-vge4ho2v	140	26	it	-PRON-	PRP
cord-344382-vge4ho2v	140	27	inhibited	inhibit	VBD
cord-344382-vge4ho2v	140	28	the	the	DT
cord-344382-vge4ho2v	140	29	expression	expression	NN
cord-344382-vge4ho2v	140	30	of	of	IN
cord-344382-vge4ho2v	140	31	viral	viral	JJ
cord-344382-vge4ho2v	140	32	matrix	matrix	NN
cord-344382-vge4ho2v	140	33	protein	protein	NN
cord-344382-vge4ho2v	140	34	,	,	,
cord-344382-vge4ho2v	140	35	caspase	caspase	NN
cord-344382-vge4ho2v	140	36	activation	activation	NN
cord-344382-vge4ho2v	140	37	,	,	,
cord-344382-vge4ho2v	140	38	and	and	CC
cord-344382-vge4ho2v	140	39	Fas	Fas	NNP
cord-344382-vge4ho2v	140	40	upregulation	upregulation	NN
cord-344382-vge4ho2v	140	41	.	.	.
cord-344382-vge4ho2v	141	1	Moreover	moreover	RB
cord-344382-vge4ho2v	141	2	,	,	,
cord-344382-vge4ho2v	141	3	administration	administration	NN
cord-344382-vge4ho2v	141	4	of	of	IN
cord-344382-vge4ho2v	141	5	GSH	GSH	NNP
cord-344382-vge4ho2v	141	6	with	with	IN
cord-344382-vge4ho2v	141	7	the	the	DT
cord-344382-vge4ho2v	141	8	drinking	drinking	NN
cord-344382-vge4ho2v	141	9	water	water	NN
cord-344382-vge4ho2v	141	10	to	to	IN
cord-344382-vge4ho2v	141	11	BALB	BALB	NNP
cord-344382-vge4ho2v	141	12	/	/	SYM
cord-344382-vge4ho2v	141	13	c	c	NN
cord-344382-vge4ho2v	141	14	mice	mouse	NNS
cord-344382-vge4ho2v	141	15	decreased	decrease	VBD
cord-344382-vge4ho2v	141	16	the	the	DT
cord-344382-vge4ho2v	141	17	viral	viral	JJ
cord-344382-vge4ho2v	141	18	titer	titer	NN
cord-344382-vge4ho2v	141	19	in	in	IN
cord-344382-vge4ho2v	141	20	both	both	CC
cord-344382-vge4ho2v	141	21	lung	lung	NN
cord-344382-vge4ho2v	141	22	and	and	CC
cord-344382-vge4ho2v	141	23	trachea	trachea	NN
cord-344382-vge4ho2v	141	24	4	4	CD
cord-344382-vge4ho2v	141	25	days	day	NNS
cord-344382-vge4ho2v	141	26	after	after	IN
cord-344382-vge4ho2v	141	27	intranasal	intranasal	NN
cord-344382-vge4ho2v	141	28	inoculation	inoculation	NN
cord-344382-vge4ho2v	141	29	of	of	IN
cord-344382-vge4ho2v	141	30	the	the	DT
cord-344382-vge4ho2v	141	31	mouse	mouse	NN
cord-344382-vge4ho2v	141	32	-	-	HYPH
cord-344382-vge4ho2v	141	33	adapted	adapt	VBN
cord-344382-vge4ho2v	141	34	influenza	influenza	NN
cord-344382-vge4ho2v	141	35	strain	strain	VB
cord-344382-vge4ho2v	141	36	A	A	NNP
cord-344382-vge4ho2v	141	37	/	/	SYM
cord-344382-vge4ho2v	141	38	X-31	X-31	NNP
cord-344382-vge4ho2v	141	39	.	.	.
cord-344382-vge4ho2v	141	40	49	49	CD
cord-344382-vge4ho2v	142	1	It	-PRON-	PRP
cord-344382-vge4ho2v	142	2	has	have	VBZ
cord-344382-vge4ho2v	142	3	also	also	RB
cord-344382-vge4ho2v	142	4	been	be	VBN
cord-344382-vge4ho2v	142	5	demonstrated	demonstrate	VBN
cord-344382-vge4ho2v	142	6	that	that	IN
cord-344382-vge4ho2v	142	7	NAC	NAC	NNP
cord-344382-vge4ho2v	142	8	inhibits	inhibit	VBZ
cord-344382-vge4ho2v	142	9	virus	virus	NN
cord-344382-vge4ho2v	142	10	replication	replication	NN
cord-344382-vge4ho2v	142	11	and	and	CC
cord-344382-vge4ho2v	142	12	expression	expression	NN
cord-344382-vge4ho2v	142	13	of	of	IN
cord-344382-vge4ho2v	142	14	pro	pro	JJ
cord-344382-vge4ho2v	142	15	-	-	JJ
cord-344382-vge4ho2v	142	16	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	142	17	molecules	molecule	NNS
cord-344382-vge4ho2v	142	18	in	in	IN
cord-344382-vge4ho2v	142	19	adenocarcinoma	adenocarcinoma	NN
cord-344382-vge4ho2v	142	20	human	human	JJ
cord-344382-vge4ho2v	142	21	alveolar	alveolar	NN
cord-344382-vge4ho2v	142	22	basal	basal	NN
cord-344382-vge4ho2v	142	23	epithelial	epithelial	NN
cord-344382-vge4ho2v	142	24	(	(	-LRB-
cord-344382-vge4ho2v	142	25	A549	A549	NNP
cord-344382-vge4ho2v	142	26	)	)	-RRB-
cord-344382-vge4ho2v	142	27	cells	cell	NNS
cord-344382-vge4ho2v	142	28	infected	infect	VBN
cord-344382-vge4ho2v	142	29	by	by	IN
cord-344382-vge4ho2v	142	30	the	the	DT
cord-344382-vge4ho2v	142	31	highly	highly	RB
cord-344382-vge4ho2v	142	32	pathogenic	pathogenic	JJ
cord-344382-vge4ho2v	142	33	H5N1	H5N1	NNP
cord-344382-vge4ho2v	142	34	influenza	influenza	NN
cord-344382-vge4ho2v	142	35	virus	virus	NN
cord-344382-vge4ho2v	142	36	.	.	.
cord-344382-vge4ho2v	143	1	50	50	CD
cord-344382-vge4ho2v	143	2	NAC	NAC	NNP
cord-344382-vge4ho2v	143	3	inhibited	inhibit	VBD
cord-344382-vge4ho2v	143	4	the	the	DT
cord-344382-vge4ho2v	143	5	pulmonary	pulmonary	JJ
cord-344382-vge4ho2v	143	6	inflammation	inflammation	NN
cord-344382-vge4ho2v	143	7	and	and	CC
cord-344382-vge4ho2v	143	8	edema	edema	NN
cord-344382-vge4ho2v	143	9	as	as	RB
cord-344382-vge4ho2v	143	10	well	well	RB
cord-344382-vge4ho2v	143	11	as	as	IN
cord-344382-vge4ho2v	143	12	myeloperoxidase	myeloperoxidase	NNP
cord-344382-vge4ho2v	143	13	(	(	-LRB-
cord-344382-vge4ho2v	143	14	MPO	MPO	NNP
cord-344382-vge4ho2v	143	15	)	)	-RRB-
cord-344382-vge4ho2v	143	16	activity	activity	NN
cord-344382-vge4ho2v	143	17	,	,	,
cord-344382-vge4ho2v	143	18	total	total	JJ
cord-344382-vge4ho2v	143	19	cells	cell	NNS
cord-344382-vge4ho2v	143	20	,	,	,
cord-344382-vge4ho2v	143	21	neutrophils	neutrophil	NNS
cord-344382-vge4ho2v	143	22	,	,	,
cord-344382-vge4ho2v	143	23	macrophages	macrophage	NNS
cord-344382-vge4ho2v	143	24	,	,	,
cord-344382-vge4ho2v	143	25	TNF	TNF	NNP
cord-344382-vge4ho2v	143	26	-	-	HYPH
cord-344382-vge4ho2v	143	27	α	α	NNP
cord-344382-vge4ho2v	143	28	,	,	,
cord-344382-vge4ho2v	143	29	IL-6	IL-6	NNP
cord-344382-vge4ho2v	143	30	,	,	,
cord-344382-vge4ho2v	143	31	IL-1β	IL-1β	NNP
cord-344382-vge4ho2v	143	32	,	,	,
cord-344382-vge4ho2v	143	33	and	and	CC
cord-344382-vge4ho2v	143	34	chemokine	chemokine	NN
cord-344382-vge4ho2v	143	35	(	(	-LRB-
cord-344382-vge4ho2v	143	36	C	c	NN
cord-344382-vge4ho2v	143	37	-	-	HYPH
cord-344382-vge4ho2v	143	38	X	x	NN
cord-344382-vge4ho2v	143	39	-	-	HYPH
cord-344382-vge4ho2v	143	40	C	c	NN
cord-344382-vge4ho2v	143	41	motif	motif	NN
cord-344382-vge4ho2v	143	42	)	)	-RRB-
cord-344382-vge4ho2v	143	43	ligand-10	ligand-10	CD
cord-344382-vge4ho2v	143	44	(	(	-LRB-
cord-344382-vge4ho2v	143	45	CXCL-10	cxcl-10	NN
cord-344382-vge4ho2v	143	46	)	)	-RRB-
cord-344382-vge4ho2v	143	47	in	in	IN
cord-344382-vge4ho2v	143	48	the	the	DT
cord-344382-vge4ho2v	143	49	bronchoalveolar	bronchoalveolar	NNP
cord-344382-vge4ho2v	143	50	lavage	lavage	NN
cord-344382-vge4ho2v	143	51	fluid	fluid	NN
cord-344382-vge4ho2v	143	52	and	and	CC
cord-344382-vge4ho2v	143	53	reduced	reduce	VBD
cord-344382-vge4ho2v	143	54	the	the	DT
cord-344382-vge4ho2v	143	55	levels	level	NNS
cord-344382-vge4ho2v	143	56	of	of	IN
cord-344382-vge4ho2v	143	57	toll	toll	NN
cord-344382-vge4ho2v	143	58	-	-	HYPH
cord-344382-vge4ho2v	143	59	like	like	JJ
cord-344382-vge4ho2v	143	60	receptor	receptor	NN
cord-344382-vge4ho2v	143	61	4	4	CD
cord-344382-vge4ho2v	143	62	(	(	-LRB-
cord-344382-vge4ho2v	143	63	TLR4	TLR4	NNP
cord-344382-vge4ho2v	143	64	)	)	-RRB-
cord-344382-vge4ho2v	143	65	protein	protein	NN
cord-344382-vge4ho2v	143	66	and	and	CC
cord-344382-vge4ho2v	143	67	mRNA	mrna	NN
cord-344382-vge4ho2v	144	1	in	in	IN
cord-344382-vge4ho2v	144	2	the	the	DT
cord-344382-vge4ho2v	144	3	lungs	lung	NNS
cord-344382-vge4ho2v	144	4	of	of	IN
cord-344382-vge4ho2v	144	5	BALB	BALB	NNP
cord-344382-vge4ho2v	144	6	/	/	SYM
cord-344382-vge4ho2v	144	7	c	c	NN
cord-344382-vge4ho2v	144	8	mice	mouse	NNS
cord-344382-vge4ho2v	144	9	inoculated	inoculate	VBN
cord-344382-vge4ho2v	144	10	intranasally	intranasally	RB
cord-344382-vge4ho2v	144	11	with	with	IN
cord-344382-vge4ho2v	144	12	A	a	DT
cord-344382-vge4ho2v	144	13	/	/	SYM
cord-344382-vge4ho2v	144	14	swine	swine	NN
cord-344382-vge4ho2v	144	15	/	/	SYM
cord-344382-vge4ho2v	144	16	HeBei/012/2008/	HeBei/012/2008/	NNP
cord-344382-vge4ho2v	144	17	H9N2	H9N2	NNP
cord-344382-vge4ho2v	144	18	influenza	influenza	NN
cord-344382-vge4ho2v	144	19	virus	virus	NN
cord-344382-vge4ho2v	144	20	.	.	.
cord-344382-vge4ho2v	145	1	51	51	CD
cord-344382-vge4ho2v	146	1	A	a	DT
cord-344382-vge4ho2v	146	2	study	study	NN
cord-344382-vge4ho2v	146	3	in	in	IN
cord-344382-vge4ho2v	146	4	the	the	DT
cord-344382-vge4ho2v	146	5	same	same	JJ
cord-344382-vge4ho2v	146	6	strain	strain	NN
cord-344382-vge4ho2v	146	7	of	of	IN
cord-344382-vge4ho2v	146	8	mice	mouse	NNS
cord-344382-vge4ho2v	146	9	showed	show	VBD
cord-344382-vge4ho2v	146	10	that	that	IN
cord-344382-vge4ho2v	146	11	old	old	JJ
cord-344382-vge4ho2v	146	12	animals	animal	NNS
cord-344382-vge4ho2v	146	13	had	have	VBD
cord-344382-vge4ho2v	146	14	lower	low	JJR
cord-344382-vge4ho2v	146	15	GSH	GSH	NNP
cord-344382-vge4ho2v	146	16	concentrations	concentration	NNS
cord-344382-vge4ho2v	146	17	than	than	IN
cord-344382-vge4ho2v	146	18	young	young	JJ
cord-344382-vge4ho2v	146	19	animals	animal	NNS
cord-344382-vge4ho2v	146	20	in	in	IN
cord-344382-vge4ho2v	146	21	spleen	spleen	NN
cord-344382-vge4ho2v	146	22	,	,	,
cord-344382-vge4ho2v	146	23	lymph	lymph	NN
cord-344382-vge4ho2v	146	24	nodes	node	NNS
cord-344382-vge4ho2v	146	25	,	,	,
cord-344382-vge4ho2v	146	26	lungs	lung	NNS
cord-344382-vge4ho2v	146	27	,	,	,
cord-344382-vge4ho2v	146	28	and	and	CC
cord-344382-vge4ho2v	146	29	pancreas	pancrea	NNS
cord-344382-vge4ho2v	146	30	.	.	.
cord-344382-vge4ho2v	147	1	The	the	DT
cord-344382-vge4ho2v	147	2	gene	gene	NN
cord-344382-vge4ho2v	147	3	expression	expression	NN
cord-344382-vge4ho2v	147	4	of	of	IN
cord-344382-vge4ho2v	147	5	endoplasmic	endoplasmic	NN
cord-344382-vge4ho2v	147	6	reticulum	reticulum	NN
cord-344382-vge4ho2v	147	7	stress	stress	NN
cord-344382-vge4ho2v	147	8	markers	marker	NNS
cord-344382-vge4ho2v	147	9	involved	involve	VBN
cord-344382-vge4ho2v	147	10	in	in	IN
cord-344382-vge4ho2v	147	11	GSH	GSH	NNP
cord-344382-vge4ho2v	147	12	metabolism	metabolism	NN
cord-344382-vge4ho2v	147	13	and	and	CC
cord-344382-vge4ho2v	147	14	folding	folding	NN
cord-344382-vge4ho2v	147	15	of	of	IN
cord-344382-vge4ho2v	147	16	proteins	protein	NNS
cord-344382-vge4ho2v	147	17	,	,	,
cord-344382-vge4ho2v	147	18	such	such	JJ
cord-344382-vge4ho2v	147	19	as	as	IN
cord-344382-vge4ho2v	147	20	Nrf2	Nrf2	NNP
cord-344382-vge4ho2v	147	21	and	and	CC
cord-344382-vge4ho2v	147	22	protein	protein	NN
cord-344382-vge4ho2v	147	23	disulfide	disulfide	NN
cord-344382-vge4ho2v	147	24	isomerase	isomerase	NN
cord-344382-vge4ho2v	147	25	(	(	-LRB-
cord-344382-vge4ho2v	147	26	PDI	PDI	NNP
cord-344382-vge4ho2v	147	27	)	)	-RRB-
cord-344382-vge4ho2v	147	28	,	,	,
cord-344382-vge4ho2v	147	29	was	be	VBD
cord-344382-vge4ho2v	147	30	reduced	reduce	VBN
cord-344382-vge4ho2v	147	31	in	in	IN
cord-344382-vge4ho2v	147	32	the	the	DT
cord-344382-vge4ho2v	147	33	lung	lung	NN
cord-344382-vge4ho2v	147	34	of	of	IN
cord-344382-vge4ho2v	147	35	old	old	JJ
cord-344382-vge4ho2v	147	36	mice	mouse	NNS
cord-344382-vge4ho2v	147	37	.	.	.
cord-344382-vge4ho2v	148	1	Treatment	treatment	NN
cord-344382-vge4ho2v	148	2	with	with	IN
cord-344382-vge4ho2v	148	3	the	the	DT
cord-344382-vge4ho2v	148	4	N	N	NNP
cord-344382-vge4ho2v	148	5	-	-	HYPH
cord-344382-vge4ho2v	148	6	butanoyl	butanoyl	NN
cord-344382-vge4ho2v	148	7	GSH	GSH	NNP
cord-344382-vge4ho2v	148	8	derivative	derivative	JJ
cord-344382-vge4ho2v	148	9	(	(	-LRB-
cord-344382-vge4ho2v	148	10	GSH	GSH	NNP
cord-344382-vge4ho2v	148	11	-	-	HYPH
cord-344382-vge4ho2v	148	12	C4	C4	NNP
cord-344382-vge4ho2v	148	13	)	)	-RRB-
cord-344382-vge4ho2v	148	14	of	of	IN
cord-344382-vge4ho2v	148	15	old	old	JJ
cord-344382-vge4ho2v	148	16	mice	mouse	NNS
cord-344382-vge4ho2v	148	17	infected	infect	VBN
cord-344382-vge4ho2v	148	18	with	with	IN
cord-344382-vge4ho2v	148	19	influenza	influenza	NN
cord-344382-vge4ho2v	148	20	A	a	DT
cord-344382-vge4ho2v	148	21	PR8	PR8	NNP
cord-344382-vge4ho2v	148	22	/	/	SYM
cord-344382-vge4ho2v	148	23	H1N1	H1N1	NNP
cord-344382-vge4ho2v	148	24	virus	virus	NN
cord-344382-vge4ho2v	148	25	increased	increase	VBD
cord-344382-vge4ho2v	148	26	GSH	GSH	NNP
cord-344382-vge4ho2v	148	27	content	content	NN
cord-344382-vge4ho2v	148	28	in	in	IN
cord-344382-vge4ho2v	148	29	organs	organ	NNS
cord-344382-vge4ho2v	148	30	,	,	,
cord-344382-vge4ho2v	148	31	reduced	reduce	VBN
cord-344382-vge4ho2v	148	32	viral	viral	JJ
cord-344382-vge4ho2v	148	33	replication	replication	NN
cord-344382-vge4ho2v	148	34	,	,	,
cord-344382-vge4ho2v	148	35	and	and	CC
cord-344382-vge4ho2v	148	36	induced	induce	VBD
cord-344382-vge4ho2v	148	37	an	an	DT
cord-344382-vge4ho2v	148	38	immune	immune	JJ
cord-344382-vge4ho2v	148	39	response	response	NN
cord-344382-vge4ho2v	148	40	,	,	,
cord-344382-vge4ho2v	148	41	in	in	IN
cord-344382-vge4ho2v	148	42	particular	particular	JJ
cord-344382-vge4ho2v	148	43	the	the	DT
cord-344382-vge4ho2v	148	44	Th1	th1	NN
cord-344382-vge4ho2v	148	45	(	(	-LRB-
cord-344382-vge4ho2v	148	46	T	T	NNP
cord-344382-vge4ho2v	148	47	helper-1	helper-1	NNP
cord-344382-vge4ho2v	148	48	)	)	-RRB-
cord-344382-vge4ho2v	148	49	cytokine	cytokine	NN
cord-344382-vge4ho2v	148	50	profile	profile	NN
cord-344382-vge4ho2v	148	51	.	.	.
cord-344382-vge4ho2v	149	1	52	52	CD
cord-344382-vge4ho2v	150	1	Influenza	Influenza	NNP
cord-344382-vge4ho2v	150	2	A	A	NNP
cord-344382-vge4ho2v	150	3	and	and	CC
cord-344382-vge4ho2v	150	4	B	b	NN
cord-344382-vge4ho2v	150	5	viruses	virus	NNS
cord-344382-vge4ho2v	150	6	and	and	CC
cord-344382-vge4ho2v	150	7	respiratory	respiratory	JJ
cord-344382-vge4ho2v	150	8	syncytial	syncytial	JJ
cord-344382-vge4ho2v	150	9	virus	virus	NN
cord-344382-vge4ho2v	150	10	(	(	-LRB-
cord-344382-vge4ho2v	150	11	RSV	RSV	NNP
cord-344382-vge4ho2v	150	12	)	)	-RRB-
cord-344382-vge4ho2v	150	13	are	be	VBP
cord-344382-vge4ho2v	150	14	responsible	responsible	JJ
cord-344382-vge4ho2v	150	15	for	for	IN
cord-344382-vge4ho2v	150	16	COPD	COPD	NNP
cord-344382-vge4ho2v	150	17	by	by	IN
cord-344382-vge4ho2v	150	18	increasing	increase	VBG
cord-344382-vge4ho2v	150	19	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	150	20	and	and	CC
cord-344382-vge4ho2v	150	21	apoptosis	apoptosis	NN
cord-344382-vge4ho2v	150	22	events	event	NNS
cord-344382-vge4ho2v	150	23	through	through	IN
cord-344382-vge4ho2v	150	24	mechanisms	mechanism	NNS
cord-344382-vge4ho2v	150	25	involving	involve	VBG
cord-344382-vge4ho2v	150	26	ROS	ROS	NNP
cord-344382-vge4ho2v	150	27	generation	generation	NN
cord-344382-vge4ho2v	150	28	and	and	CC
cord-344382-vge4ho2v	150	29	release	release	NN
cord-344382-vge4ho2v	150	30	of	of	IN
cord-344382-vge4ho2v	150	31	mucins	mucin	NNS
cord-344382-vge4ho2v	150	32	from	from	IN
cord-344382-vge4ho2v	150	33	epithelial	epithelial	JJ
cord-344382-vge4ho2v	150	34	cells	cell	NNS
cord-344382-vge4ho2v	150	35	.	.	.
cord-344382-vge4ho2v	151	1	NAC	NAC	NNP
cord-344382-vge4ho2v	151	2	inhibited	inhibit	VBD
cord-344382-vge4ho2v	151	3	the	the	DT
cord-344382-vge4ho2v	151	4	replication	replication	NN
cord-344382-vge4ho2v	151	5	of	of	IN
cord-344382-vge4ho2v	151	6	these	these	DT
cord-344382-vge4ho2v	151	7	viruses	virus	NNS
cord-344382-vge4ho2v	151	8	and	and	CC
cord-344382-vge4ho2v	151	9	restored	restore	VBD
cord-344382-vge4ho2v	151	10	the	the	DT
cord-344382-vge4ho2v	151	11	normal	normal	JJ
cord-344382-vge4ho2v	151	12	functions	function	NNS
cord-344382-vge4ho2v	151	13	of	of	IN
cord-344382-vge4ho2v	151	14	alveolar	alveolar	NN
cord-344382-vge4ho2v	151	15	type	type	NN
cord-344382-vge4ho2v	151	16	II	II	NNP
cord-344382-vge4ho2v	151	17	A549	a549	JJ
cord-344382-vge4ho2v	151	18	cells	cell	NNS
cord-344382-vge4ho2v	151	19	by	by	IN
cord-344382-vge4ho2v	151	20	modulating	modulate	VBG
cord-344382-vge4ho2v	151	21	MUC5AC	MUC5AC	NNP
cord-344382-vge4ho2v	151	22	overexpression	overexpression	NN
cord-344382-vge4ho2v	151	23	and	and	CC
cord-344382-vge4ho2v	151	24	release	release	NN
cord-344382-vge4ho2v	151	25	and	and	CC
cord-344382-vge4ho2v	151	26	by	by	IN
cord-344382-vge4ho2v	151	27	inhibiting	inhibit	VBG
cord-344382-vge4ho2v	151	28	IL-8	IL-8	NNP
cord-344382-vge4ho2v	151	29	,	,	,
cord-344382-vge4ho2v	151	30	IL-6	IL-6	NNP
cord-344382-vge4ho2v	151	31	,	,	,
cord-344382-vge4ho2v	151	32	and	and	CC
cord-344382-vge4ho2v	151	33	TNF	TNF	NNP
cord-344382-vge4ho2v	151	34	-	-	HYPH
cord-344382-vge4ho2v	151	35	α	α	NNP
cord-344382-vge4ho2v	151	36	as	as	RB
cord-344382-vge4ho2v	151	37	well	well	RB
cord-344382-vge4ho2v	151	38	as	as	IN
cord-344382-vge4ho2v	151	39	NF	nf	NN
cord-344382-vge4ho2v	151	40	-	-	HYPH
cord-344382-vge4ho2v	151	41	κB	κb	CD
cord-344382-vge4ho2v	151	42	translocation	translocation	NN
cord-344382-vge4ho2v	151	43	to	to	IN
cord-344382-vge4ho2v	151	44	the	the	DT
cord-344382-vge4ho2v	151	45	nucleus	nucleus	NN
cord-344382-vge4ho2v	151	46	and	and	CC
cord-344382-vge4ho2v	151	47	phosphorylation	phosphorylation	NN
cord-344382-vge4ho2v	151	48	of	of	IN
cord-344382-vge4ho2v	151	49	MAPK	MAPK	NNP
cord-344382-vge4ho2v	151	50	p38	p38	CD
cord-344382-vge4ho2v	151	51	.	.	.
cord-344382-vge4ho2v	152	1	53	53	CD
cord-344382-vge4ho2v	153	1	Furthermore	furthermore	RB
cord-344382-vge4ho2v	153	2	,	,	,
cord-344382-vge4ho2v	153	3	it	-PRON-	PRP
cord-344382-vge4ho2v	153	4	has	have	VBZ
cord-344382-vge4ho2v	153	5	been	be	VBN
cord-344382-vge4ho2v	153	6	known	know	VBN
cord-344382-vge4ho2v	153	7	for	for	IN
cord-344382-vge4ho2v	153	8	almost	almost	RB
cord-344382-vge4ho2v	153	9	30	30	CD
cord-344382-vge4ho2v	153	10	years	year	NNS
cord-344382-vge4ho2v	153	11	that	that	WDT
cord-344382-vge4ho2v	153	12	GSH	GSH	NNP
cord-344382-vge4ho2v	153	13	plays	play	VBZ
cord-344382-vge4ho2v	153	14	an	an	DT
cord-344382-vge4ho2v	153	15	important	important	JJ
cord-344382-vge4ho2v	153	16	defense	defense	NN
cord-344382-vge4ho2v	153	17	role	role	NN
cord-344382-vge4ho2v	153	18	against	against	IN
cord-344382-vge4ho2v	153	19	HIV	HIV	NNP
cord-344382-vge4ho2v	153	20	and	and	CC
cord-344382-vge4ho2v	153	21	that	that	IN
cord-344382-vge4ho2v	153	22	NAC	NAC	NNP
cord-344382-vge4ho2v	153	23	may	may	MD
cord-344382-vge4ho2v	153	24	exert	exert	VB
cord-344382-vge4ho2v	153	25	protective	protective	JJ
cord-344382-vge4ho2v	153	26	effects	effect	NNS
cord-344382-vge4ho2v	153	27	toward	toward	IN
cord-344382-vge4ho2v	153	28	this	this	DT
cord-344382-vge4ho2v	153	29	viral	viral	JJ
cord-344382-vge4ho2v	153	30	infection	infection	NN
cord-344382-vge4ho2v	153	31	.	.	.
cord-344382-vge4ho2v	154	1	For	for	IN
cord-344382-vge4ho2v	154	2	instance	instance	NN
cord-344382-vge4ho2v	154	3	,	,	,
cord-344382-vge4ho2v	154	4	in	in	IN
cord-344382-vge4ho2v	154	5	agreement	agreement	NN
cord-344382-vge4ho2v	154	6	with	with	IN
cord-344382-vge4ho2v	154	7	data	datum	NNS
cord-344382-vge4ho2v	154	8	obtained	obtain	VBN
cord-344382-vge4ho2v	154	9	in	in	IN
cord-344382-vge4ho2v	154	10	cells	cell	NNS
cord-344382-vge4ho2v	154	11	exposed	expose	VBN
cord-344382-vge4ho2v	154	12	to	to	IN
cord-344382-vge4ho2v	154	13	herpesvirus	herpesvirus	NN
cord-344382-vge4ho2v	154	14	type	type	NN
cord-344382-vge4ho2v	154	15	1	1	CD
cord-344382-vge4ho2v	154	16	(	(	-LRB-
cord-344382-vge4ho2v	154	17	DNA	dna	NN
cord-344382-vge4ho2v	154	18	virus	virus	NN
cord-344382-vge4ho2v	154	19	)	)	-RRB-
cord-344382-vge4ho2v	154	20	or	or	CC
cord-344382-vge4ho2v	154	21	to	to	IN
cord-344382-vge4ho2v	154	22	Sendai	Sendai	NNP
cord-344382-vge4ho2v	154	23	(	(	-LRB-
cord-344382-vge4ho2v	154	24	an	an	DT
cord-344382-vge4ho2v	154	25	RNA	RNA	NNP
cord-344382-vge4ho2v	154	26	virus	virus	NN
cord-344382-vge4ho2v	154	27	belonging	belong	VBG
cord-344382-vge4ho2v	154	28	to	to	IN
cord-344382-vge4ho2v	154	29	the	the	DT
cord-344382-vge4ho2v	154	30	family	family	NN
cord-344382-vge4ho2v	154	31	of	of	IN
cord-344382-vge4ho2v	154	32	Paramyxoviridae	Paramyxoviridae	NNP
cord-344382-vge4ho2v	154	33	)	)	-RRB-
cord-344382-vge4ho2v	154	34	,	,	,
cord-344382-vge4ho2v	154	35	it	-PRON-	PRP
cord-344382-vge4ho2v	154	36	was	be	VBD
cord-344382-vge4ho2v	154	37	shown	show	VBN
cord-344382-vge4ho2v	154	38	that	that	IN
cord-344382-vge4ho2v	154	39	GSH	GSH	NNP
cord-344382-vge4ho2v	154	40	inhibits	inhibit	VBZ
cord-344382-vge4ho2v	154	41	HIV	HIV	NNP
cord-344382-vge4ho2v	154	42	envelope	envelope	NN
cord-344382-vge4ho2v	154	43	glycoproteins	glycoprotein	NNS
cord-344382-vge4ho2v	154	44	(	(	-LRB-
cord-344382-vge4ho2v	154	45	gp120	gp120	NNP
cord-344382-vge4ho2v	154	46	)	)	-RRB-
cord-344382-vge4ho2v	154	47	and	and	CC
cord-344382-vge4ho2v	154	48	interferes	interfere	VBZ
cord-344382-vge4ho2v	154	49	with	with	IN
cord-344382-vge4ho2v	154	50	late	late	JJ
cord-344382-vge4ho2v	154	51	stages	stage	NNS
cord-344382-vge4ho2v	154	52	of	of	IN
cord-344382-vge4ho2v	154	53	virus	virus	NN
cord-344382-vge4ho2v	154	54	replication	replication	NN
cord-344382-vge4ho2v	154	55	in	in	IN
cord-344382-vge4ho2v	154	56	chronically	chronically	RB
cord-344382-vge4ho2v	154	57	infected	infect	VBN
cord-344382-vge4ho2v	154	58	macrophages	macrophage	NNS
cord-344382-vge4ho2v	154	59	,	,	,
cord-344382-vge4ho2v	154	60	a	a	DT
cord-344382-vge4ho2v	154	61	known	know	VBN
cord-344382-vge4ho2v	154	62	reservoir	reservoir	NN
cord-344382-vge4ho2v	154	63	of	of	IN
cord-344382-vge4ho2v	154	64	the	the	DT
cord-344382-vge4ho2v	154	65	virus	virus	NN
cord-344382-vge4ho2v	154	66	in	in	IN
cord-344382-vge4ho2v	154	67	the	the	DT
cord-344382-vge4ho2v	154	68	body	body	NN
cord-344382-vge4ho2v	154	69	.	.	.
cord-344382-vge4ho2v	155	1	54	54	CD
cord-344382-vge4ho2v	156	1	Both	both	DT
cord-344382-vge4ho2v	156	2	GSH	GSH	NNP
cord-344382-vge4ho2v	156	3	and	and	CC
cord-344382-vge4ho2v	156	4	NAC	NAC	NNP
cord-344382-vge4ho2v	156	5	inhibited	inhibit	VBD
cord-344382-vge4ho2v	156	6	the	the	DT
cord-344382-vge4ho2v	156	7	induction	induction	NN
cord-344382-vge4ho2v	156	8	of	of	IN
cord-344382-vge4ho2v	156	9	HIV-1	HIV-1	NNP
cord-344382-vge4ho2v	156	10	expression	expression	NN
cord-344382-vge4ho2v	156	11	in	in	IN
cord-344382-vge4ho2v	156	12	a	a	DT
cord-344382-vge4ho2v	156	13	chronically	chronically	RB
cord-344382-vge4ho2v	156	14	HIV-1-infected	hiv-1-infecte	VBN
cord-344382-vge4ho2v	156	15	promonocytic	promonocytic	JJ
cord-344382-vge4ho2v	156	16	cell	cell	NN
cord-344382-vge4ho2v	156	17	line	line	NN
cord-344382-vge4ho2v	156	18	(	(	-LRB-
cord-344382-vge4ho2v	156	19	U1	U1	NNP
cord-344382-vge4ho2v	156	20	/	/	SYM
cord-344382-vge4ho2v	156	21	HIV	HIV	NNP
cord-344382-vge4ho2v	156	22	)	)	-RRB-
cord-344382-vge4ho2v	156	23	and	and	CC
cord-344382-vge4ho2v	156	24	in	in	IN
cord-344382-vge4ho2v	156	25	human	human	JJ
cord-344382-vge4ho2v	156	26	primary	primary	JJ
cord-344382-vge4ho2v	156	27	monocyte	monocyte	NNP
cord-344382-vge4ho2v	156	28	/	/	SYM
cord-344382-vge4ho2v	156	29	macrophages	macrophage	NNS
cord-344382-vge4ho2v	156	30	cultured	culture	VBN
cord-344382-vge4ho2v	156	31	in	in	IN
cord-344382-vge4ho2v	156	32	vitro	vitro	FW
cord-344382-vge4ho2v	156	33	,	,	,
cord-344382-vge4ho2v	156	34	where	where	WRB
cord-344382-vge4ho2v	156	35	both	both	DT
cord-344382-vge4ho2v	156	36	thiols	thiol	NNS
cord-344382-vge4ho2v	156	37	decreased	decrease	VBD
cord-344382-vge4ho2v	156	38	HIV-1	HIV-1	NNP
cord-344382-vge4ho2v	156	39	p24	p24	NN
cord-344382-vge4ho2v	156	40	antigen	antigen	NN
cord-344382-vge4ho2v	156	41	levels	level	NNS
cord-344382-vge4ho2v	156	42	as	as	RB
cord-344382-vge4ho2v	156	43	well	well	RB
cord-344382-vge4ho2v	156	44	as	as	IN
cord-344382-vge4ho2v	156	45	reverse	reverse	JJ
cord-344382-vge4ho2v	156	46	transcriptase	transcriptase	NN
cord-344382-vge4ho2v	156	47	activity	activity	NN
cord-344382-vge4ho2v	156	48	.	.	.
cord-344382-vge4ho2v	157	1	55	55	CD
cord-344382-vge4ho2v	158	1	Interestingly	interestingly	RB
cord-344382-vge4ho2v	158	2	,	,	,
cord-344382-vge4ho2v	158	3	NAC	NAC	NNP
cord-344382-vge4ho2v	158	4	appears	appear	VBZ
cord-344382-vge4ho2v	158	5	to	to	TO
cord-344382-vge4ho2v	158	6	synergize	synergize	VB
cord-344382-vge4ho2v	158	7	with	with	IN
cord-344382-vge4ho2v	158	8	antivirals	antiviral	NNS
cord-344382-vge4ho2v	158	9	in	in	IN
cord-344382-vge4ho2v	158	10	the	the	DT
cord-344382-vge4ho2v	158	11	protection	protection	NN
cord-344382-vge4ho2v	158	12	toward	toward	IN
cord-344382-vge4ho2v	158	13	influenza	influenza	NN
cord-344382-vge4ho2v	158	14	in	in	IN
cord-344382-vge4ho2v	158	15	mouse	mouse	NN
cord-344382-vge4ho2v	158	16	models	model	NNS
cord-344382-vge4ho2v	158	17	,	,	,
cord-344382-vge4ho2v	158	18	as	as	IN
cord-344382-vge4ho2v	158	19	shown	show	VBN
cord-344382-vge4ho2v	158	20	with	with	IN
cord-344382-vge4ho2v	158	21	ribavirin	ribavirin	NN
cord-344382-vge4ho2v	158	22	56	56	CD
cord-344382-vge4ho2v	158	23	and	and	CC
cord-344382-vge4ho2v	158	24	oseltamivir	oseltamivir	NNS
cord-344382-vge4ho2v	158	25	.	.	.
cord-344382-vge4ho2v	159	1	57	57	CD
cord-344382-vge4ho2v	159	2	Smokers	smoker	NNS
cord-344382-vge4ho2v	159	3	are	be	VBP
cord-344382-vge4ho2v	159	4	more	more	RBR
cord-344382-vge4ho2v	159	5	vulnerable	vulnerable	JJ
cord-344382-vge4ho2v	159	6	to	to	IN
cord-344382-vge4ho2v	159	7	infectious	infectious	JJ
cord-344382-vge4ho2v	159	8	diseases	disease	NNS
cord-344382-vge4ho2v	159	9	,	,	,
cord-344382-vge4ho2v	159	10	as	as	IN
cord-344382-vge4ho2v	159	11	shown	show	VBN
cord-344382-vge4ho2v	159	12	in	in	IN
cord-344382-vge4ho2v	159	13	the	the	DT
cord-344382-vge4ho2v	159	14	case	case	NN
cord-344382-vge4ho2v	159	15	of	of	IN
cord-344382-vge4ho2v	159	16	influenza	influenza	NN
cord-344382-vge4ho2v	159	17	and	and	CC
cord-344382-vge4ho2v	159	18	of	of	IN
cord-344382-vge4ho2v	159	19	the	the	DT
cord-344382-vge4ho2v	159	20	MERS	MERS	NNP
cord-344382-vge4ho2v	159	21	-	-	HYPH
cord-344382-vge4ho2v	159	22	CoV	CoV	NNP
cord-344382-vge4ho2v	159	23	outbreak	outbreak	NN
cord-344382-vge4ho2v	159	24	.	.	.
cord-344382-vge4ho2v	160	1	An	an	DT
cord-344382-vge4ho2v	160	2	analysis	analysis	NN
cord-344382-vge4ho2v	160	3	of	of	IN
cord-344382-vge4ho2v	160	4	the	the	DT
cord-344382-vge4ho2v	160	5	literature	literature	NN
cord-344382-vge4ho2v	160	6	suggests	suggest	VBZ
cord-344382-vge4ho2v	160	7	that	that	IN
cord-344382-vge4ho2v	160	8	smoking	smoking	NN
cord-344382-vge4ho2v	160	9	is	be	VBZ
cord-344382-vge4ho2v	160	10	most	most	RBS
cord-344382-vge4ho2v	160	11	likely	likely	RB
cord-344382-vge4ho2v	160	12	associated	associate	VBN
cord-344382-vge4ho2v	160	13	with	with	IN
cord-344382-vge4ho2v	160	14	the	the	DT
cord-344382-vge4ho2v	160	15	negative	negative	JJ
cord-344382-vge4ho2v	160	16	progression	progression	NN
cord-344382-vge4ho2v	160	17	and	and	CC
cord-344382-vge4ho2v	160	18	adverse	adverse	JJ
cord-344382-vge4ho2v	160	19	outcomes	outcome	NNS
cord-344382-vge4ho2v	160	20	of	of	IN
cord-344382-vge4ho2v	160	21	COVID-19	covid-19	NN
cord-344382-vge4ho2v	160	22	.	.	.
cord-344382-vge4ho2v	161	1	58	58	CD
cord-344382-vge4ho2v	161	2	Exposure	exposure	NN
cord-344382-vge4ho2v	161	3	to	to	IN
cord-344382-vge4ho2v	161	4	cigarette	cigarette	NN
cord-344382-vge4ho2v	161	5	smoke	smoke	NN
cord-344382-vge4ho2v	161	6	increases	increase	VBZ
cord-344382-vge4ho2v	161	7	ROS	ROS	NNP
cord-344382-vge4ho2v	161	8	levels	level	NNS
cord-344382-vge4ho2v	161	9	and	and	CC
cord-344382-vge4ho2v	161	10	causes	cause	VBZ
cord-344382-vge4ho2v	161	11	a	a	DT
cord-344382-vge4ho2v	161	12	drop	drop	NN
cord-344382-vge4ho2v	161	13	in	in	IN
cord-344382-vge4ho2v	161	14	GSH	GSH	NNP
cord-344382-vge4ho2v	161	15	intracellular	intracellular	JJ
cord-344382-vge4ho2v	161	16	concentrations	concentration	NNS
cord-344382-vge4ho2v	161	17	.	.	.
cord-344382-vge4ho2v	162	1	59	59	CD
cord-344382-vge4ho2v	162	2	Aldehydes	Aldehydes	NNPS
cord-344382-vge4ho2v	162	3	in	in	IN
cord-344382-vge4ho2v	162	4	cigarette	cigarette	NN
cord-344382-vge4ho2v	162	5	smoke	smoke	NN
cord-344382-vge4ho2v	162	6	deplete	deplete	VB
cord-344382-vge4ho2v	162	7	the	the	DT
cord-344382-vge4ho2v	162	8	total	total	JJ
cord-344382-vge4ho2v	162	9	available	available	JJ
cord-344382-vge4ho2v	162	10	GSH	GSH	NNP
cord-344382-vge4ho2v	162	11	pool	pool	NN
cord-344382-vge4ho2v	162	12	by	by	IN
cord-344382-vge4ho2v	162	13	reacting	react	VBG
cord-344382-vge4ho2v	162	14	to	to	TO
cord-344382-vge4ho2v	162	15	form	form	VB
cord-344382-vge4ho2v	162	16	nonreducible	nonreducible	JJ
cord-344382-vge4ho2v	162	17	GSH	GSH	NNP
cord-344382-vge4ho2v	162	18	-	-	HYPH
cord-344382-vge4ho2v	162	19	aldehydes	aldehyde	NNS
cord-344382-vge4ho2v	162	20	derivatives	derivative	NNS
cord-344382-vge4ho2v	162	21	.	.	.
cord-344382-vge4ho2v	163	1	60	60	CD
cord-344382-vge4ho2v	163	2	GSH	GSH	NNP
cord-344382-vge4ho2v	163	3	depletion	depletion	NN
cord-344382-vge4ho2v	163	4	accelerates	accelerate	VBZ
cord-344382-vge4ho2v	163	5	cigarette	cigarette	NN
cord-344382-vge4ho2v	163	6	smoke	smoke	NN
cord-344382-vge4ho2v	163	7	-	-	HYPH
cord-344382-vge4ho2v	163	8	induced	induce	VBN
cord-344382-vge4ho2v	163	9	inflammation	inflammation	NN
cord-344382-vge4ho2v	163	10	and	and	CC
cord-344382-vge4ho2v	163	11	airspace	airspace	NN
cord-344382-vge4ho2v	163	12	enlargement	enlargement	NN
cord-344382-vge4ho2v	163	13	,	,	,
cord-344382-vge4ho2v	163	14	and	and	CC
cord-344382-vge4ho2v	163	15	the	the	DT
cord-344382-vge4ho2v	163	16	GSH	GSH	NNP
cord-344382-vge4ho2v	163	17	adaptive	adaptive	JJ
cord-344382-vge4ho2v	163	18	response	response	NN
cord-344382-vge4ho2v	163	19	declines	decline	VBZ
cord-344382-vge4ho2v	163	20	with	with	IN
cord-344382-vge4ho2v	163	21	age	age	NN
cord-344382-vge4ho2v	163	22	.	.	.
cord-344382-vge4ho2v	164	1	61	61	CD
cord-344382-vge4ho2v	165	1	By	by	IN
cord-344382-vge4ho2v	165	2	increasing	increase	VBG
cord-344382-vge4ho2v	165	3	GSH	GSH	NNP
cord-344382-vge4ho2v	165	4	production	production	NN
cord-344382-vge4ho2v	165	5	,	,	,
cord-344382-vge4ho2v	165	6	NAC	NAC	NNP
cord-344382-vge4ho2v	165	7	has	have	VBZ
cord-344382-vge4ho2v	165	8	the	the	DT
cord-344382-vge4ho2v	165	9	ability	ability	NN
cord-344382-vge4ho2v	165	10	to	to	TO
cord-344382-vge4ho2v	165	11	modulate	modulate	VB
cord-344382-vge4ho2v	165	12	a	a	DT
cord-344382-vge4ho2v	165	13	large	large	JJ
cord-344382-vge4ho2v	165	14	variety	variety	NN
cord-344382-vge4ho2v	165	15	of	of	IN
cord-344382-vge4ho2v	165	16	smoking	smoking	NN
cord-344382-vge4ho2v	165	17	-	-	HYPH
cord-344382-vge4ho2v	165	18	related	relate	VBN
cord-344382-vge4ho2v	165	19	end	end	NN
cord-344382-vge4ho2v	165	20	-	-	HYPH
cord-344382-vge4ho2v	165	21	points	point	NNS
cord-344382-vge4ho2v	165	22	and	and	CC
cord-344382-vge4ho2v	165	23	cancer	cancer	NN
cord-344382-vge4ho2v	165	24	in	in	IN
cord-344382-vge4ho2v	165	25	experimental	experimental	JJ
cord-344382-vge4ho2v	165	26	test	test	NN
cord-344382-vge4ho2v	165	27	systems	system	NNS
cord-344382-vge4ho2v	165	28	,	,	,
cord-344382-vge4ho2v	165	29	due	due	IN
cord-344382-vge4ho2v	165	30	to	to	IN
cord-344382-vge4ho2v	165	31	many	many	JJ
cord-344382-vge4ho2v	165	32	interconnected	interconnect	VBN
cord-344382-vge4ho2v	165	33	mechanisms	mechanism	NNS
cord-344382-vge4ho2v	165	34	and	and	CC
cord-344382-vge4ho2v	165	35	properties	property	NNS
cord-344382-vge4ho2v	165	36	.	.	.
cord-344382-vge4ho2v	166	1	17	17	CD
cord-344382-vge4ho2v	166	2	,	,	,
cord-344382-vge4ho2v	166	3	62	62	CD
cord-344382-vge4ho2v	167	1	In	in	IN
cord-344382-vge4ho2v	167	2	addition	addition	NN
cord-344382-vge4ho2v	167	3	,	,	,
cord-344382-vge4ho2v	167	4	NAC	NAC	NNP
cord-344382-vge4ho2v	167	5	was	be	VBD
cord-344382-vge4ho2v	167	6	shown	show	VBN
cord-344382-vge4ho2v	167	7	to	to	TO
cord-344382-vge4ho2v	167	8	attenuate	attenuate	VB
cord-344382-vge4ho2v	167	9	several	several	JJ
cord-344382-vge4ho2v	167	10	biomarker	biomarker	NN
cord-344382-vge4ho2v	167	11	alterations	alteration	NNS
cord-344382-vge4ho2v	167	12	in	in	IN
cord-344382-vge4ho2v	167	13	a	a	DT
cord-344382-vge4ho2v	167	14	randomized	randomized	JJ
cord-344382-vge4ho2v	167	15	,	,	,
cord-344382-vge4ho2v	167	16	double	double	JJ
cord-344382-vge4ho2v	167	17	-	-	HYPH
cord-344382-vge4ho2v	167	18	blind	blind	JJ
cord-344382-vge4ho2v	167	19	,	,	,
cord-344382-vge4ho2v	167	20	placebo	placebo	NN
cord-344382-vge4ho2v	167	21	-	-	HYPH
cord-344382-vge4ho2v	167	22	controlled	control	VBN
cord-344382-vge4ho2v	167	23	,	,	,
cord-344382-vge4ho2v	167	24	Phase	Phase	NNP
cord-344382-vge4ho2v	167	25	II	II	NNP
cord-344382-vge4ho2v	167	26	chemoprevention	chemoprevention	NN
cord-344382-vge4ho2v	167	27	trial	trial	NN
cord-344382-vge4ho2v	167	28	in	in	IN
cord-344382-vge4ho2v	167	29	heavy	heavy	JJ
cord-344382-vge4ho2v	167	30	smokers	smoker	NNS
cord-344382-vge4ho2v	167	31	who	who	WP
cord-344382-vge4ho2v	167	32	received	receive	VBD
cord-344382-vge4ho2v	167	33	NAC	NAC	NNP
cord-344382-vge4ho2v	167	34	tablets	tablet	NNS
cord-344382-vge4ho2v	167	35	(	(	-LRB-
cord-344382-vge4ho2v	167	36	600	600	CD
cord-344382-vge4ho2v	167	37	mg	mg	NNP
cord-344382-vge4ho2v	167	38	)	)	-RRB-
cord-344382-vge4ho2v	167	39	twice	twice	RB
cord-344382-vge4ho2v	167	40	daily	daily	RB
cord-344382-vge4ho2v	167	41	for	for	IN
cord-344382-vge4ho2v	167	42	6	6	CD
cord-344382-vge4ho2v	167	43	months	month	NNS
cord-344382-vge4ho2v	167	44	.	.	.
cord-344382-vge4ho2v	168	1	63	63	CD
cord-344382-vge4ho2v	168	2	 	 	_SP
cord-344382-vge4ho2v	169	1	NAC	NAC	NNP
cord-344382-vge4ho2v	169	2	is	be	VBZ
cord-344382-vge4ho2v	169	3	approved	approve	VBN
cord-344382-vge4ho2v	169	4	by	by	IN
cord-344382-vge4ho2v	169	5	FDA	FDA	NNP
cord-344382-vge4ho2v	169	6	under	under	IN
cord-344382-vge4ho2v	169	7	various	various	JJ
cord-344382-vge4ho2v	169	8	formulations	formulation	NNS
cord-344382-vge4ho2v	169	9	and	and	CC
cord-344382-vge4ho2v	169	10	is	be	VBZ
cord-344382-vge4ho2v	169	11	popular	popular	JJ
cord-344382-vge4ho2v	169	12	as	as	IN
cord-344382-vge4ho2v	169	13	a	a	DT
cord-344382-vge4ho2v	169	14	health	health	NN
cord-344382-vge4ho2v	169	15	supplement	supplement	NN
cord-344382-vge4ho2v	169	16	,	,	,
cord-344382-vge4ho2v	169	17	this	this	DT
cord-344382-vge4ho2v	169	18	molecule	molecule	NN
cord-344382-vge4ho2v	169	19	having	have	VBG
cord-344382-vge4ho2v	169	20	been	be	VBN
cord-344382-vge4ho2v	169	21	proposed	propose	VBN
cord-344382-vge4ho2v	169	22	as	as	IN
cord-344382-vge4ho2v	169	23	a	a	DT
cord-344382-vge4ho2v	169	24	nutraceutical	nutraceutical	NN
cord-344382-vge4ho2v	169	25	that	that	WDT
cord-344382-vge4ho2v	169	26	might	may	MD
cord-344382-vge4ho2v	169	27	aid	aid	VB
cord-344382-vge4ho2v	169	28	the	the	DT
cord-344382-vge4ho2v	169	29	control	control	NN
cord-344382-vge4ho2v	169	30	of	of	IN
cord-344382-vge4ho2v	169	31	RNA	RNA	NNP
cord-344382-vge4ho2v	169	32	viruses	virus	NNS
cord-344382-vge4ho2v	169	33	including	include	VBG
cord-344382-vge4ho2v	169	34	influenza	influenza	NN
cord-344382-vge4ho2v	169	35	and	and	CC
cord-344382-vge4ho2v	169	36	coronavirus	coronavirus	NN
cord-344382-vge4ho2v	169	37	.	.	.
cord-344382-vge4ho2v	170	1	[	[	-LRB-
cord-344382-vge4ho2v	170	2	64	64	CD
cord-344382-vge4ho2v	170	3	]	]	-RRB-
cord-344382-vge4ho2v	170	4	[	[	-LRB-
cord-344382-vge4ho2v	170	5	65	65	CD
cord-344382-vge4ho2v	170	6	]	]	-RRB-
cord-344382-vge4ho2v	171	1	[	[	-LRB-
cord-344382-vge4ho2v	171	2	66	66	CD
cord-344382-vge4ho2v	171	3	]	]	-RRB-
cord-344382-vge4ho2v	172	1	Almost	almost	RB
cord-344382-vge4ho2v	172	2	60	60	CD
cord-344382-vge4ho2v	172	3	years	year	NNS
cord-344382-vge4ho2v	172	4	of	of	IN
cord-344382-vge4ho2v	172	5	experience	experience	NN
cord-344382-vge4ho2v	172	6	in	in	IN
cord-344382-vge4ho2v	172	7	the	the	DT
cord-344382-vge4ho2v	172	8	prophylaxis	prophylaxis	NN
cord-344382-vge4ho2v	172	9	and	and	CC
cord-344382-vge4ho2v	172	10	therapy	therapy	NN
cord-344382-vge4ho2v	172	11	of	of	IN
cord-344382-vge4ho2v	172	12	a	a	DT
cord-344382-vge4ho2v	172	13	variety	variety	NN
cord-344382-vge4ho2v	172	14	of	of	IN
cord-344382-vge4ho2v	172	15	clinical	clinical	JJ
cord-344382-vge4ho2v	172	16	conditions	condition	NNS
cord-344382-vge4ho2v	172	17	have	have	VBP
cord-344382-vge4ho2v	172	18	established	establish	VBN
cord-344382-vge4ho2v	172	19	the	the	DT
cord-344382-vge4ho2v	172	20	safety	safety	NN
cord-344382-vge4ho2v	172	21	of	of	IN
cord-344382-vge4ho2v	172	22	this	this	DT
cord-344382-vge4ho2v	172	23	drug	drug	NN
cord-344382-vge4ho2v	172	24	,	,	,
cord-344382-vge4ho2v	172	25	even	even	RB
cord-344382-vge4ho2v	172	26	at	at	IN
cord-344382-vge4ho2v	172	27	very	very	RB
cord-344382-vge4ho2v	172	28	high	high	JJ
cord-344382-vge4ho2v	172	29	doses	dose	NNS
cord-344382-vge4ho2v	172	30	and	and	CC
cord-344382-vge4ho2v	172	31	for	for	IN
cord-344382-vge4ho2v	172	32	long	long	JJ
cord-344382-vge4ho2v	172	33	-	-	HYPH
cord-344382-vge4ho2v	172	34	term	term	NN
cord-344382-vge4ho2v	172	35	treatments	treatment	NNS
cord-344382-vge4ho2v	172	36	.	.	.
cord-344382-vge4ho2v	173	1	Drug	drug	NN
cord-344382-vge4ho2v	173	2	repurposing	repurposing	NN
cord-344382-vge4ho2v	173	3	is	be	VBZ
cord-344382-vge4ho2v	173	4	the	the	DT
cord-344382-vge4ho2v	173	5	fastest	fast	JJS
cord-344382-vge4ho2v	173	6	strategy	strategy	NN
cord-344382-vge4ho2v	173	7	toward	toward	IN
cord-344382-vge4ho2v	173	8	an	an	DT
cord-344382-vge4ho2v	173	9	effective	effective	JJ
cord-344382-vge4ho2v	173	10	and	and	CC
cord-344382-vge4ho2v	173	11	accessible	accessible	JJ
cord-344382-vge4ho2v	173	12	treatment	treatment	NN
cord-344382-vge4ho2v	173	13	against	against	IN
cord-344382-vge4ho2v	173	14	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	173	15	before	before	IN
cord-344382-vge4ho2v	173	16	a	a	DT
cord-344382-vge4ho2v	173	17	vaccine	vaccine	NN
cord-344382-vge4ho2v	173	18	is	be	VBZ
cord-344382-vge4ho2v	173	19	available	available	JJ
cord-344382-vge4ho2v	173	20	,	,	,
cord-344382-vge4ho2v	173	21	67	67	CD
cord-344382-vge4ho2v	173	22	and	and	CC
cord-344382-vge4ho2v	173	23	molecules	molecule	NNS
cord-344382-vge4ho2v	173	24	working	work	VBG
cord-344382-vge4ho2v	173	25	via	via	IN
cord-344382-vge4ho2v	173	26	multiple	multiple	JJ
cord-344382-vge4ho2v	173	27	mechanisms	mechanism	NNS
cord-344382-vge4ho2v	173	28	of	of	IN
cord-344382-vge4ho2v	173	29	action	action	NN
cord-344382-vge4ho2v	173	30	,	,	,
cord-344382-vge4ho2v	173	31	such	such	JJ
cord-344382-vge4ho2v	173	32	as	as	IN
cord-344382-vge4ho2v	173	33	NAC	NAC	NNP
cord-344382-vge4ho2v	173	34	,	,	,
cord-344382-vge4ho2v	173	35	are	be	VBP
cord-344382-vge4ho2v	173	36	more	more	RBR
cord-344382-vge4ho2v	173	37	likely	likely	JJ
cord-344382-vge4ho2v	173	38	to	to	TO
cord-344382-vge4ho2v	173	39	be	be	VB
cord-344382-vge4ho2v	173	40	effective	effective	JJ
cord-344382-vge4ho2v	173	41	as	as	IN
cord-344382-vge4ho2v	173	42	compared	compare	VBN
cord-344382-vge4ho2v	173	43	with	with	IN
cord-344382-vge4ho2v	173	44	drugs	drug	NNS
cord-344382-vge4ho2v	173	45	having	have	VBG
cord-344382-vge4ho2v	173	46	a	a	DT
cord-344382-vge4ho2v	173	47	single	single	JJ
cord-344382-vge4ho2v	173	48	target	target	NN
cord-344382-vge4ho2v	173	49	.	.	.
cord-344382-vge4ho2v	174	1	Based	base	VBN
cord-344382-vge4ho2v	174	2	on	on	IN
cord-344382-vge4ho2v	174	3	the	the	DT
cord-344382-vge4ho2v	174	4	herein	herein	RB
cord-344382-vge4ho2v	174	5	discussed	discuss	VBN
cord-344382-vge4ho2v	174	6	mechanistic	mechanistic	JJ
cord-344382-vge4ho2v	174	7	premises	premise	NNS
cord-344382-vge4ho2v	174	8	,	,	,
cord-344382-vge4ho2v	174	9	NAC	NAC	NNP
cord-344382-vge4ho2v	174	10	may	may	MD
cord-344382-vge4ho2v	174	11	be	be	VB
cord-344382-vge4ho2v	174	12	proposed	propose	VBN
cord-344382-vge4ho2v	174	13	both	both	CC
cord-344382-vge4ho2v	174	14	in	in	IN
cord-344382-vge4ho2v	174	15	the	the	DT
cord-344382-vge4ho2v	174	16	prevention	prevention	NN
cord-344382-vge4ho2v	174	17	and	and	CC
cord-344382-vge4ho2v	174	18	in	in	IN
cord-344382-vge4ho2v	174	19	the	the	DT
cord-344382-vge4ho2v	174	20	therapy	therapy	NN
cord-344382-vge4ho2v	174	21	of	of	IN
cord-344382-vge4ho2v	174	22	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	174	23	.	.	.
cord-344382-vge4ho2v	175	1	In	in	IN
cord-344382-vge4ho2v	175	2	particular	particular	JJ
cord-344382-vge4ho2v	175	3	,	,	,
cord-344382-vge4ho2v	175	4	the	the	DT
cord-344382-vge4ho2v	175	5	oral	oral	JJ
cord-344382-vge4ho2v	175	6	administration	administration	NN
cord-344382-vge4ho2v	175	7	of	of	IN
cord-344382-vge4ho2v	175	8	NAC	NAC	NNP
cord-344382-vge4ho2v	175	9	,	,	,
cord-344382-vge4ho2v	175	10	at	at	IN
cord-344382-vge4ho2v	175	11	the	the	DT
cord-344382-vge4ho2v	175	12	dose	dose	NN
cord-344382-vge4ho2v	175	13	of	of	IN
cord-344382-vge4ho2v	175	14	600	600	CD
cord-344382-vge4ho2v	175	15	mg	mg	NNS
cord-344382-vge4ho2v	175	16	twice	twice	RB
cord-344382-vge4ho2v	175	17	daily	daily	RB
cord-344382-vge4ho2v	175	18	,	,	,
cord-344382-vge4ho2v	175	19	may	may	MD
cord-344382-vge4ho2v	175	20	be	be	VB
cord-344382-vge4ho2v	175	21	proposed	propose	VBN
cord-344382-vge4ho2v	175	22	for	for	IN
cord-344382-vge4ho2v	175	23	preventive	preventive	JJ
cord-344382-vge4ho2v	175	24	purposes	purpose	NNS
cord-344382-vge4ho2v	175	25	aimed	aim	VBN
cord-344382-vge4ho2v	175	26	at	at	IN
cord-344382-vge4ho2v	175	27	attenuating	attenuate	VBG
cord-344382-vge4ho2v	175	28	the	the	DT
cord-344382-vge4ho2v	175	29	risk	risk	NN
cord-344382-vge4ho2v	175	30	of	of	IN
cord-344382-vge4ho2v	175	31	developing	develop	VBG
cord-344382-vge4ho2v	175	32	COVID-19	covid-19	VB
cord-344382-vge4ho2v	175	33	and	and	CC
cord-344382-vge4ho2v	175	34	its	-PRON-	PRP$
cord-344382-vge4ho2v	175	35	severity	severity	NN
cord-344382-vge4ho2v	175	36	during	during	IN
cord-344382-vge4ho2v	175	37	epidemic	epidemic	JJ
cord-344382-vge4ho2v	175	38	periods	period	NNS
cord-344382-vge4ho2v	175	39	,	,	,
cord-344382-vge4ho2v	175	40	as	as	IN
cord-344382-vge4ho2v	175	41	we	-PRON-	PRP
cord-344382-vge4ho2v	175	42	previously	previously	RB
cord-344382-vge4ho2v	175	43	demonstrated	demonstrate	VBD
cord-344382-vge4ho2v	175	44	in	in	IN
cord-344382-vge4ho2v	175	45	the	the	DT
cord-344382-vge4ho2v	175	46	case	case	NN
cord-344382-vge4ho2v	175	47	of	of	IN
cord-344382-vge4ho2v	175	48	influenza	influenza	NN
cord-344382-vge4ho2v	175	49	and	and	CC
cord-344382-vge4ho2v	175	50	influenza	influenza	NN
cord-344382-vge4ho2v	175	51	-	-	HYPH
cord-344382-vge4ho2v	175	52	like	like	JJ
cord-344382-vge4ho2v	175	53	illnesses	illness	NNS
cord-344382-vge4ho2v	175	54	,	,	,
cord-344382-vge4ho2v	175	55	47	47	CD
cord-344382-vge4ho2v	175	56	especially	especially	RB
cord-344382-vge4ho2v	175	57	in	in	IN
cord-344382-vge4ho2v	175	58	elderly	elderly	JJ
cord-344382-vge4ho2v	175	59	people	people	NNS
cord-344382-vge4ho2v	175	60	and	and	CC
cord-344382-vge4ho2v	175	61	in	in	IN
cord-344382-vge4ho2v	175	62	individuals	individual	NNS
cord-344382-vge4ho2v	175	63	who	who	WP
cord-344382-vge4ho2v	175	64	suffer	suffer	VBP
cord-344382-vge4ho2v	175	65	from	from	IN
cord-344382-vge4ho2v	175	66	chronic	chronic	JJ
cord-344382-vge4ho2v	175	67	conditions	condition	NNS
cord-344382-vge4ho2v	175	68	that	that	WDT
cord-344382-vge4ho2v	175	69	predispose	predispose	VBP
cord-344382-vge4ho2v	175	70	them	-PRON-	PRP
cord-344382-vge4ho2v	175	71	to	to	IN
cord-344382-vge4ho2v	175	72	this	this	DT
cord-344382-vge4ho2v	175	73	kind	kind	NN
cord-344382-vge4ho2v	175	74	of	of	IN
cord-344382-vge4ho2v	175	75	diseases	disease	NNS
cord-344382-vge4ho2v	175	76	and	and	CC
cord-344382-vge4ho2v	175	77	increase	increase	VB
cord-344382-vge4ho2v	175	78	their	-PRON-	PRP$
cord-344382-vge4ho2v	175	79	severity	severity	NN
cord-344382-vge4ho2v	175	80	.	.	.
cord-344382-vge4ho2v	176	1	Persons	person	NNS
cord-344382-vge4ho2v	176	2	who	who	WP
cord-344382-vge4ho2v	176	3	have	have	VBP
cord-344382-vge4ho2v	176	4	been	be	VBN
cord-344382-vge4ho2v	176	5	in	in	IN
cord-344382-vge4ho2v	176	6	proximity	proximity	NN
cord-344382-vge4ho2v	176	7	of	of	IN
cord-344382-vge4ho2v	176	8	infected	infected	JJ
cord-344382-vge4ho2v	176	9	SARS	SARS	NNP
cord-344382-vge4ho2v	176	10	-	-	HYPH
cord-344382-vge4ho2v	176	11	CoV-2	CoV-2	NNP
cord-344382-vge4ho2v	176	12	carriers	carrier	NNS
cord-344382-vge4ho2v	176	13	,	,	,
cord-344382-vge4ho2v	176	14	including	include	VBG
cord-344382-vge4ho2v	176	15	those	those	DT
cord-344382-vge4ho2v	176	16	detected	detect	VBN
cord-344382-vge4ho2v	176	17	by	by	IN
cord-344382-vge4ho2v	176	18	means	mean	NNS
cord-344382-vge4ho2v	176	19	of	of	IN
cord-344382-vge4ho2v	176	20	smartphone	smartphone	NN
cord-344382-vge4ho2v	176	21	contact	contact	NN
cord-344382-vge4ho2v	176	22	tracing	trace	VBG
cord-344382-vge4ho2v	176	23	apps	app	NNS
cord-344382-vge4ho2v	176	24	,	,	,
cord-344382-vge4ho2v	176	25	may	may	MD
cord-344382-vge4ho2v	176	26	be	be	VB
cord-344382-vge4ho2v	176	27	an	an	DT
cord-344382-vge4ho2v	176	28	additional	additional	JJ
cord-344382-vge4ho2v	176	29	target	target	NN
cord-344382-vge4ho2v	176	30	for	for	IN
cord-344382-vge4ho2v	176	31	taking	take	VBG
cord-344382-vge4ho2v	176	32	oral	oral	JJ
cord-344382-vge4ho2v	176	33	NAC	NAC	NNP
cord-344382-vge4ho2v	176	34	in	in	IN
cord-344382-vge4ho2v	176	35	order	order	NN
cord-344382-vge4ho2v	176	36	to	to	TO
cord-344382-vge4ho2v	176	37	decrease	decrease	VB
cord-344382-vge4ho2v	176	38	the	the	DT
cord-344382-vge4ho2v	176	39	risk	risk	NN
cord-344382-vge4ho2v	176	40	of	of	IN
cord-344382-vge4ho2v	176	41	developing	develop	VBG
cord-344382-vge4ho2v	176	42	COVID-19	covid-19	CD
cord-344382-vge4ho2v	176	43	.	.	.
cord-344382-vge4ho2v	177	1	In	in	IN
cord-344382-vge4ho2v	177	2	addition	addition	NN
cord-344382-vge4ho2v	177	3	,	,	,
cord-344382-vge4ho2v	177	4	NAC	NAC	NNP
cord-344382-vge4ho2v	177	5	has	have	VBZ
cord-344382-vge4ho2v	177	6	been	be	VBN
cord-344382-vge4ho2v	177	7	shown	show	VBN
cord-344382-vge4ho2v	177	8	to	to	TO
cord-344382-vge4ho2v	177	9	exert	exert	VB
cord-344382-vge4ho2v	177	10	protective	protective	JJ
cord-344382-vge4ho2v	177	11	mechanisms	mechanism	NNS
cord-344382-vge4ho2v	177	12	against	against	IN
cord-344382-vge4ho2v	177	13	a	a	DT
cord-344382-vge4ho2v	177	14	variety	variety	NN
cord-344382-vge4ho2v	177	15	of	of	IN
cord-344382-vge4ho2v	177	16	conditions	condition	NNS
cord-344382-vge4ho2v	177	17	associated	associate	VBN
cord-344382-vge4ho2v	177	18	with	with	IN
cord-344382-vge4ho2v	177	19	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	177	20	and	and	CC
cord-344382-vge4ho2v	177	21	co	co	NNS
cord-344382-vge4ho2v	177	22	-	-	NNS
cord-344382-vge4ho2v	177	23	morbidities	morbidity	NNS
cord-344382-vge4ho2v	177	24	thereof	thereof	RB
cord-344382-vge4ho2v	177	25	,	,	,
cord-344382-vge4ho2v	177	26	also	also	RB
cord-344382-vge4ho2v	177	27	including	include	VBG
cord-344382-vge4ho2v	177	28	cardiovascular	cardiovascular	JJ
cord-344382-vge4ho2v	177	29	diseases	disease	NNS
cord-344382-vge4ho2v	177	30	.	.	.
cord-344382-vge4ho2v	178	1	16	16	CD
cord-344382-vge4ho2v	179	1	Given	give	VBN
cord-344382-vge4ho2v	179	2	that	that	DT
cord-344382-vge4ho2v	179	3	cardiac	cardiac	JJ
cord-344382-vge4ho2v	179	4	injury	injury	NN
cord-344382-vge4ho2v	179	5	and	and	CC
cord-344382-vge4ho2v	179	6	thrombosis	thrombosis	NN
cord-344382-vge4ho2v	179	7	are	be	VBP
cord-344382-vge4ho2v	179	8	well	well	RB
cord-344382-vge4ho2v	179	9	established	establish	VBN
cord-344382-vge4ho2v	179	10	as	as	IN
cord-344382-vge4ho2v	179	11	potentially	potentially	RB
cord-344382-vge4ho2v	179	12	lethal	lethal	JJ
cord-344382-vge4ho2v	179	13	complications	complication	NNS
cord-344382-vge4ho2v	179	14	in	in	IN
cord-344382-vge4ho2v	179	15	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	179	16	,	,	,
cord-344382-vge4ho2v	179	17	it	-PRON-	PRP
cord-344382-vge4ho2v	179	18	is	be	VBZ
cord-344382-vge4ho2v	179	19	noteworthy	noteworthy	JJ
cord-344382-vge4ho2v	179	20	that	that	IN
cord-344382-vge4ho2v	179	21	intravenously	intravenously	RB
cord-344382-vge4ho2v	179	22	administered	administer	VBN
cord-344382-vge4ho2v	179	23	NAC	NAC	NNP
cord-344382-vge4ho2v	179	24	has	have	VBZ
cord-344382-vge4ho2v	179	25	been	be	VBN
cord-344382-vge4ho2v	179	26	shown	show	VBN
cord-344382-vge4ho2v	179	27	to	to	TO
cord-344382-vge4ho2v	179	28	potentiate	potentiate	VB
cord-344382-vge4ho2v	179	29	the	the	DT
cord-344382-vge4ho2v	179	30	vasodilator	vasodilator	NN
cord-344382-vge4ho2v	179	31	,	,	,
cord-344382-vge4ho2v	179	32	anti	anti	JJ
cord-344382-vge4ho2v	179	33	-	-	JJ
cord-344382-vge4ho2v	179	34	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	179	35	and	and	CC
cord-344382-vge4ho2v	179	36	antiaggregatory	antiaggregatory	JJ
cord-344382-vge4ho2v	179	37	effects	effect	NNS
cord-344382-vge4ho2v	179	38	of	of	IN
cord-344382-vge4ho2v	179	39	nitroglycerin	nitroglycerin	NN
cord-344382-vge4ho2v	179	40	,	,	,
cord-344382-vge4ho2v	179	41	and	and	CC
cord-344382-vge4ho2v	179	42	this	this	DT
cord-344382-vge4ho2v	179	43	useful	useful	JJ
cord-344382-vge4ho2v	179	44	interaction	interaction	NN
cord-344382-vge4ho2v	179	45	has	have	VBZ
cord-344382-vge4ho2v	179	46	been	be	VBN
cord-344382-vge4ho2v	179	47	translated	translate	VBN
cord-344382-vge4ho2v	179	48	into	into	IN
cord-344382-vge4ho2v	179	49	improving	improve	VBG
cord-344382-vge4ho2v	179	50	outcomes	outcome	NNS
cord-344382-vge4ho2v	179	51	,	,	,
cord-344382-vge4ho2v	179	52	such	such	JJ
cord-344382-vge4ho2v	179	53	as	as	IN
cord-344382-vge4ho2v	179	54	in	in	IN
cord-344382-vge4ho2v	179	55	acute	acute	JJ
cord-344382-vge4ho2v	179	56	myocardial	myocardial	JJ
cord-344382-vge4ho2v	179	57	infarction	infarction	NN
cord-344382-vge4ho2v	179	58	,	,	,
cord-344382-vge4ho2v	179	59	unstable	unstable	JJ
cord-344382-vge4ho2v	179	60	angina	angina	NN
cord-344382-vge4ho2v	179	61	and	and	CC
cord-344382-vge4ho2v	179	62	acute	acute	JJ
cord-344382-vge4ho2v	179	63	pulmonary	pulmonary	JJ
cord-344382-vge4ho2v	179	64	edema	edema	NN
cord-344382-vge4ho2v	179	65	.	.	.
cord-344382-vge4ho2v	180	1	68	68	CD
cord-344382-vge4ho2v	180	2	,	,	,
cord-344382-vge4ho2v	180	3	69	69	CD
cord-344382-vge4ho2v	180	4	Administration	Administration	NNP
cord-344382-vge4ho2v	180	5	of	of	IN
cord-344382-vge4ho2v	180	6	NAC	NAC	NNP
cord-344382-vge4ho2v	180	7	has	have	VBZ
cord-344382-vge4ho2v	180	8	been	be	VBN
cord-344382-vge4ho2v	180	9	included	include	VBN
cord-344382-vge4ho2v	180	10	among	among	IN
cord-344382-vge4ho2v	180	11	the	the	DT
cord-344382-vge4ho2v	180	12	possible	possible	JJ
cord-344382-vge4ho2v	180	13	strategies	strategy	NNS
cord-344382-vge4ho2v	180	14	aimed	aim	VBN
cord-344382-vge4ho2v	180	15	at	at	IN
cord-344382-vge4ho2v	180	16	preserving	preserve	VBG
cord-344382-vge4ho2v	180	17	endothelial	endothelial	JJ
cord-344382-vge4ho2v	180	18	function	function	NN
cord-344382-vge4ho2v	180	19	and	and	CC
cord-344382-vge4ho2v	180	20	limiting	limit	VBG
cord-344382-vge4ho2v	180	21	microthrombosis	microthrombosis	NN
cord-344382-vge4ho2v	180	22	in	in	IN
cord-344382-vge4ho2v	180	23	severe	severe	JJ
cord-344382-vge4ho2v	180	24	forms	form	NNS
cord-344382-vge4ho2v	180	25	of	of	IN
cord-344382-vge4ho2v	180	26	COVID-19	covid-19	NN
cord-344382-vge4ho2v	180	27	.	.	.
cord-344382-vge4ho2v	180	28	70	70	CD
cord-344382-vge4ho2v	181	1	In	in	IN
cord-344382-vge4ho2v	181	2	case	case	NN
cord-344382-vge4ho2v	181	3	of	of	IN
cord-344382-vge4ho2v	181	4	severe	severe	JJ
cord-344382-vge4ho2v	181	5	COVID-19	covid-19	JJ
cord-344382-vge4ho2v	181	6	forms	form	NNS
cord-344382-vge4ho2v	181	7	with	with	IN
cord-344382-vge4ho2v	181	8	pulmonary	pulmonary	JJ
cord-344382-vge4ho2v	181	9	and/or	and/or	CC
cord-344382-vge4ho2v	181	10	systemic	systemic	JJ
cord-344382-vge4ho2v	181	11	symptoms	symptom	NNS
cord-344382-vge4ho2v	181	12	,	,	,
cord-344382-vge4ho2v	181	13	intravenously	intravenously	RB
cord-344382-vge4ho2v	181	14	administered	administer	VBD
cord-344382-vge4ho2v	181	15	NAC	NAC	NNP
cord-344382-vge4ho2v	181	16	at	at	IN
cord-344382-vge4ho2v	181	17	the	the	DT
cord-344382-vge4ho2v	181	18	high	high	JJ
cord-344382-vge4ho2v	181	19	doses	dose	NNS
cord-344382-vge4ho2v	181	20	that	that	WDT
cord-344382-vge4ho2v	181	21	are	be	VBP
cord-344382-vge4ho2v	181	22	commonly	commonly	RB
cord-344382-vge4ho2v	181	23	used	use	VBN
cord-344382-vge4ho2v	181	24	in	in	IN
cord-344382-vge4ho2v	181	25	case	case	NN
cord-344382-vge4ho2v	181	26	of	of	IN
cord-344382-vge4ho2v	181	27	paracetamol	paracetamol	JJ
cord-344382-vge4ho2v	181	28	intoxication	intoxication	NN
cord-344382-vge4ho2v	181	29	,	,	,
cord-344382-vge4ho2v	181	30	given	give	VBN
cord-344382-vge4ho2v	181	31	at	at	IN
cord-344382-vge4ho2v	181	32	the	the	DT
cord-344382-vge4ho2v	181	33	first	first	JJ
cord-344382-vge4ho2v	181	34	onset	onset	NN
cord-344382-vge4ho2v	181	35	of	of	IN
cord-344382-vge4ho2v	181	36	chest	chest	NN
cord-344382-vge4ho2v	181	37	symptoms	symptom	NNS
cord-344382-vge4ho2v	181	38	,	,	,
cord-344382-vge4ho2v	181	39	would	would	MD
cord-344382-vge4ho2v	181	40	be	be	VB
cord-344382-vge4ho2v	181	41	expected	expect	VBN
cord-344382-vge4ho2v	181	42	to	to	TO
cord-344382-vge4ho2v	181	43	play	play	VB
cord-344382-vge4ho2v	181	44	an	an	DT
cord-344382-vge4ho2v	181	45	adjuvant	adjuvant	JJ
cord-344382-vge4ho2v	181	46	therapeutic	therapeutic	JJ
cord-344382-vge4ho2v	181	47	role	role	NN
cord-344382-vge4ho2v	181	48	in	in	IN
cord-344382-vge4ho2v	181	49	combination	combination	NN
cord-344382-vge4ho2v	181	50	with	with	IN
cord-344382-vge4ho2v	181	51	antivirals	antiviral	NNS
cord-344382-vge4ho2v	181	52	or	or	CC
cord-344382-vge4ho2v	181	53	other	other	JJ
cord-344382-vge4ho2v	181	54	drugs	drug	NNS
cord-344382-vge4ho2v	181	55	.	.	.
cord-344382-vge4ho2v	182	1	A	a	DT
cord-344382-vge4ho2v	182	2	potential	potential	JJ
cord-344382-vge4ho2v	182	3	role	role	NN
cord-344382-vge4ho2v	182	4	of	of	IN
cord-344382-vge4ho2v	182	5	NAC	NAC	NNP
cord-344382-vge4ho2v	182	6	and	and	CC
cord-344382-vge4ho2v	182	7	copper	copper	NN
cord-344382-vge4ho2v	182	8	in	in	IN
cord-344382-vge4ho2v	182	9	combination	combination	NN
cord-344382-vge4ho2v	182	10	with	with	IN
cord-344382-vge4ho2v	182	11	candidate	candidate	NN
cord-344382-vge4ho2v	182	12	antiviral	antiviral	JJ
cord-344382-vge4ho2v	182	13	treatments	treatment	NNS
cord-344382-vge4ho2v	182	14	against	against	IN
cord-344382-vge4ho2v	182	15	SARS	SARS	NNP
cord-344382-vge4ho2v	182	16	-	-	HYPH
cord-344382-vge4ho2v	182	17	CoV-2	CoV-2	NNP
cord-344382-vge4ho2v	182	18	,	,	,
cord-344382-vge4ho2v	182	19	such	such	JJ
cord-344382-vge4ho2v	182	20	as	as	IN
cord-344382-vge4ho2v	182	21	remdesivir	remdesivir	NNP
cord-344382-vge4ho2v	182	22	,	,	,
cord-344382-vge4ho2v	182	23	has	have	VBZ
cord-344382-vge4ho2v	182	24	been	be	VBN
cord-344382-vge4ho2v	182	25	hypothesized	hypothesize	VBN
cord-344382-vge4ho2v	182	26	based	base	VBN
cord-344382-vge4ho2v	182	27	on	on	IN
cord-344382-vge4ho2v	182	28	a	a	DT
cord-344382-vge4ho2v	182	29	systematic	systematic	JJ
cord-344382-vge4ho2v	182	30	literature	literature	NN
cord-344382-vge4ho2v	182	31	search	search	NN
cord-344382-vge4ho2v	182	32	.	.	.
cord-344382-vge4ho2v	183	1	71	71	CD
cord-344382-vge4ho2v	184	1	Clearly	clearly	RB
cord-344382-vge4ho2v	184	2	,	,	,
cord-344382-vge4ho2v	184	3	the	the	DT
cord-344382-vge4ho2v	184	4	potential	potential	JJ
cord-344382-vge4ho2v	184	5	anti	anti	JJ
cord-344382-vge4ho2v	184	6	-	-	JJ
cord-344382-vge4ho2v	184	7	COVID-19	covid-19	JJ
cord-344382-vge4ho2v	184	8	mechanisms	mechanism	NNS
cord-344382-vge4ho2v	184	9	and	and	CC
cord-344382-vge4ho2v	184	10	properties	property	NNS
cord-344382-vge4ho2v	184	11	of	of	IN
cord-344382-vge4ho2v	184	12	this	this	DT
cord-344382-vge4ho2v	184	13	thiol	thiol	NN
cord-344382-vge4ho2v	184	14	have	have	VBP
cord-344382-vge4ho2v	184	15	to	to	TO
cord-344382-vge4ho2v	184	16	be	be	VB
cord-344382-vge4ho2v	184	17	substantiated	substantiate	VBN
cord-344382-vge4ho2v	184	18	in	in	IN
cord-344382-vge4ho2v	184	19	controlled	control	VBN
cord-344382-vge4ho2v	184	20	clinical	clinical	JJ
cord-344382-vge4ho2v	184	21	trials	trial	NNS
cord-344382-vge4ho2v	184	22	,	,	,
cord-344382-vge4ho2v	184	23	some	some	DT
cord-344382-vge4ho2v	184	24	of	of	IN
cord-344382-vge4ho2v	184	25	which	which	WDT
cord-344382-vge4ho2v	184	26	are	be	VBP
cord-344382-vge4ho2v	184	27	now	now	RB
cord-344382-vge4ho2v	184	28	in	in	IN
cord-344382-vge4ho2v	184	29	progress	progress	NN
cord-344382-vge4ho2v	184	30	.	.	.
cord-344382-vge4ho2v	185	1	12	12	CD
cord-344382-vge4ho2v	185	2	,	,	,
cord-344382-vge4ho2v	185	3	72	72	CD
cord-344382-vge4ho2v	185	4	 	 	_SP
cord-344382-vge4ho2v	185	5	COVID-19	covid-19	NN
cord-344382-vge4ho2v	185	6	:	:	:
cord-344382-vge4ho2v	185	7	immunopathology	immunopathology	NN
cord-344382-vge4ho2v	185	8	and	and	CC
cord-344382-vge4ho2v	185	9	its	-PRON-	PRP$
cord-344382-vge4ho2v	185	10	implications	implication	NNS
cord-344382-vge4ho2v	185	11	for	for	IN
cord-344382-vge4ho2v	185	12	therapy	therapy	NN
cord-344382-vge4ho2v	185	13	Molecular	molecular	JJ
cord-344382-vge4ho2v	185	14	immune	immune	JJ
cord-344382-vge4ho2v	185	15	pathogenesis	pathogenesis	NN
cord-344382-vge4ho2v	185	16	and	and	CC
cord-344382-vge4ho2v	185	17	diagnosis	diagnosis	NN
cord-344382-vge4ho2v	185	18	of	of	IN
cord-344382-vge4ho2v	185	19	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	185	20	A	a	DT
cord-344382-vge4ho2v	185	21	current	current	JJ
cord-344382-vge4ho2v	185	22	review	review	NN
cord-344382-vge4ho2v	185	23	of	of	IN
cord-344382-vge4ho2v	185	24	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	185	25	for	for	IN
cord-344382-vge4ho2v	185	26	the	the	DT
cord-344382-vge4ho2v	185	27	cardiovascular	cardiovascular	JJ
cord-344382-vge4ho2v	185	28	specialist	specialist	NN
cord-344382-vge4ho2v	185	29	Characteristics	characteristic	NNS
cord-344382-vge4ho2v	185	30	of	of	IN
cord-344382-vge4ho2v	185	31	SARS	SARS	NNP
cord-344382-vge4ho2v	185	32	-	-	HYPH
cord-344382-vge4ho2v	185	33	CoV-2	CoV-2	NNP
cord-344382-vge4ho2v	185	34	patients	patient	NNS
cord-344382-vge4ho2v	185	35	dying	die	VBG
cord-344382-vge4ho2v	185	36	in	in	IN
cord-344382-vge4ho2v	185	37	Italy	Italy	NNP
cord-344382-vge4ho2v	185	38	Sexual	sexual	JJ
cord-344382-vge4ho2v	185	39	dimorphism	dimorphism	NN
cord-344382-vge4ho2v	185	40	in	in	IN
cord-344382-vge4ho2v	185	41	glutathione	glutathione	NN
cord-344382-vge4ho2v	185	42	metabolism	metabolism	NN
cord-344382-vge4ho2v	185	43	and	and	CC
cord-344382-vge4ho2v	185	44	glutathione	glutathione	NN
cord-344382-vge4ho2v	185	45	-	-	HYPH
cord-344382-vge4ho2v	185	46	dependent	dependent	JJ
cord-344382-vge4ho2v	185	47	responses	response	NNS
cord-344382-vge4ho2v	186	1	Reactive	reactive	JJ
cord-344382-vge4ho2v	186	2	oxygen	oxygen	NN
cord-344382-vge4ho2v	186	3	species	specie	NNS
cord-344382-vge4ho2v	186	4	as	as	IN
cord-344382-vge4ho2v	186	5	an	an	DT
cord-344382-vge4ho2v	186	6	initiator	initiator	NN
cord-344382-vge4ho2v	186	7	of	of	IN
cord-344382-vge4ho2v	186	8	toxic	toxic	JJ
cord-344382-vge4ho2v	186	9	innate	innate	JJ
cord-344382-vge4ho2v	186	10	immune	immune	JJ
cord-344382-vge4ho2v	186	11	responses	response	NNS
cord-344382-vge4ho2v	186	12	in	in	IN
cord-344382-vge4ho2v	186	13	retort	retort	NN
cord-344382-vge4ho2v	186	14	to	to	IN
cord-344382-vge4ho2v	186	15	SARS	SARS	NNP
cord-344382-vge4ho2v	186	16	-	-	HYPH
cord-344382-vge4ho2v	186	17	CoV-2	CoV-2	NNP
cord-344382-vge4ho2v	186	18	in	in	IN
cord-344382-vge4ho2v	186	19	an	an	DT
cord-344382-vge4ho2v	186	20	ageing	age	VBG
cord-344382-vge4ho2v	186	21	population	population	NN
cord-344382-vge4ho2v	186	22	,	,	,
cord-344382-vge4ho2v	186	23	consider	consider	VB
cord-344382-vge4ho2v	186	24	N	n	NN
cord-344382-vge4ho2v	186	25	-	-	HYPH
cord-344382-vge4ho2v	186	26	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	186	27	as	as	IN
cord-344382-vge4ho2v	186	28	early	early	JJ
cord-344382-vge4ho2v	186	29	therapeutic	therapeutic	JJ
cord-344382-vge4ho2v	186	30	intervention	intervention	NN
cord-344382-vge4ho2v	186	31	Clinical	clinical	JJ
cord-344382-vge4ho2v	186	32	features	feature	NNS
cord-344382-vge4ho2v	186	33	of	of	IN
cord-344382-vge4ho2v	186	34	patients	patient	NNS
cord-344382-vge4ho2v	186	35	infected	infect	VBN
cord-344382-vge4ho2v	186	36	with	with	IN
cord-344382-vge4ho2v	186	37	the	the	DT
cord-344382-vge4ho2v	186	38	2019	2019	CD
cord-344382-vge4ho2v	186	39	novel	novel	NN
cord-344382-vge4ho2v	186	40	coronavirus	coronavirus	NN
cord-344382-vge4ho2v	186	41	(	(	-LRB-
cord-344382-vge4ho2v	186	42	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	186	43	Endogenous	endogenous	JJ
cord-344382-vge4ho2v	186	44	deficiency	deficiency	NN
cord-344382-vge4ho2v	186	45	of	of	IN
cord-344382-vge4ho2v	186	46	glutathione	glutathione	NN
cord-344382-vge4ho2v	186	47	as	as	IN
cord-344382-vge4ho2v	186	48	the	the	DT
cord-344382-vge4ho2v	186	49	most	most	RBS
cord-344382-vge4ho2v	186	50	likely	likely	JJ
cord-344382-vge4ho2v	186	51	cause	cause	NN
cord-344382-vge4ho2v	186	52	of	of	IN
cord-344382-vge4ho2v	186	53	serious	serious	JJ
cord-344382-vge4ho2v	186	54	manifestations	manifestation	NNS
cord-344382-vge4ho2v	186	55	and	and	CC
cord-344382-vge4ho2v	186	56	death	death	NN
cord-344382-vge4ho2v	186	57	from	from	IN
cord-344382-vge4ho2v	186	58	novel	novel	JJ
cord-344382-vge4ho2v	186	59	coronavirus	coronavirus	NN
cord-344382-vge4ho2v	186	60	infection(COVID-19	infection(covid-19	RB
cord-344382-vge4ho2v	186	61	)	)	-RRB-
cord-344382-vge4ho2v	186	62	:	:	:
cord-344382-vge4ho2v	186	63	a	a	DT
cord-344382-vge4ho2v	186	64	hypothesis	hypothesis	NN
cord-344382-vge4ho2v	186	65	based	base	VBN
cord-344382-vge4ho2v	186	66	on	on	IN
cord-344382-vge4ho2v	186	67	literature	literature	NN
cord-344382-vge4ho2v	186	68	data	datum	NNS
cord-344382-vge4ho2v	186	69	and	and	CC
cord-344382-vge4ho2v	186	70	own	own	JJ
cord-344382-vge4ho2v	186	71	observations	observation	NNS
cord-344382-vge4ho2v	186	72	SARS	SARS	NNP
cord-344382-vge4ho2v	186	73	-	-	HYPH
cord-344382-vge4ho2v	186	74	CoV-2	CoV-2	NNP
cord-344382-vge4ho2v	186	75	cell	cell	NN
cord-344382-vge4ho2v	186	76	entry	entry	NN
cord-344382-vge4ho2v	186	77	depends	depend	VBZ
cord-344382-vge4ho2v	186	78	on	on	IN
cord-344382-vge4ho2v	186	79	ACE2	ACE2	NNP
cord-344382-vge4ho2v	186	80	and	and	CC
cord-344382-vge4ho2v	186	81	TMPRSS2	TMPRSS2	NNP
cord-344382-vge4ho2v	186	82	and	and	CC
cord-344382-vge4ho2v	186	83	is	be	VBZ
cord-344382-vge4ho2v	186	84	blocked	block	VBN
cord-344382-vge4ho2v	186	85	by	by	IN
cord-344382-vge4ho2v	186	86	a	a	DT
cord-344382-vge4ho2v	186	87	clinically	clinically	RB
cord-344382-vge4ho2v	186	88	proven	prove	VBN
cord-344382-vge4ho2v	186	89	protease	protease	NN
cord-344382-vge4ho2v	186	90	inhibitor	inhibitor	NN
cord-344382-vge4ho2v	186	91	Impact	impact	NN
cord-344382-vge4ho2v	186	92	of	of	IN
cord-344382-vge4ho2v	186	93	thiol	thiol	NN
cord-344382-vge4ho2v	186	94	-	-	HYPH
cord-344382-vge4ho2v	186	95	disulfide	disulfide	NN
cord-344382-vge4ho2v	186	96	balance	balance	NN
cord-344382-vge4ho2v	186	97	on	on	IN
cord-344382-vge4ho2v	186	98	the	the	DT
cord-344382-vge4ho2v	186	99	binding	binding	NN
cord-344382-vge4ho2v	186	100	of	of	IN
cord-344382-vge4ho2v	186	101	Covid-19	covid-19	NN
cord-344382-vge4ho2v	186	102	spike	spike	NN
cord-344382-vge4ho2v	186	103	protein	protein	NN
cord-344382-vge4ho2v	186	104	with	with	IN
cord-344382-vge4ho2v	186	105	angiotensin	angiotensin	NN
cord-344382-vge4ho2v	186	106	converting	convert	VBG
cord-344382-vge4ho2v	186	107	enzyme	enzyme	NN
cord-344382-vge4ho2v	186	108	2	2	CD
cord-344382-vge4ho2v	186	109	receptor	receptor	NN
cord-344382-vge4ho2v	186	110	N	n	CD
cord-344382-vge4ho2v	186	111	-	-	HYPH
cord-344382-vge4ho2v	186	112	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	187	1	inhibits	inhibit	VBZ
cord-344382-vge4ho2v	187	2	angiotensin	angiotensin	NN
cord-344382-vge4ho2v	187	3	converting	convert	VBG
cord-344382-vge4ho2v	187	4	enzyme	enzyme	NN
cord-344382-vge4ho2v	187	5	in	in	IN
cord-344382-vge4ho2v	187	6	vivo	vivo	NNP
cord-344382-vge4ho2v	187	7	N	N	NNP
cord-344382-vge4ho2v	187	8	-	-	HYPH
cord-344382-vge4ho2v	187	9	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	187	10	as	as	IN
cord-344382-vge4ho2v	187	11	a	a	DT
cord-344382-vge4ho2v	187	12	potential	potential	JJ
cord-344382-vge4ho2v	187	13	treatment	treatment	NN
cord-344382-vge4ho2v	187	14	for	for	IN
cord-344382-vge4ho2v	187	15	novel	novel	JJ
cord-344382-vge4ho2v	187	16	coronavirus	coronavirus	NN
cord-344382-vge4ho2v	187	17	disease	disease	NN
cord-344382-vge4ho2v	187	18	Regulation	regulation	NN
cord-344382-vge4ho2v	187	19	of	of	IN
cord-344382-vge4ho2v	187	20	glutathione	glutathione	NN
cord-344382-vge4ho2v	187	21	synthesis	synthesis	NN
cord-344382-vge4ho2v	187	22	N	N	NNP
cord-344382-vge4ho2v	187	23	-	-	HYPH
cord-344382-vge4ho2v	187	24	Acetylcysteine	Acetylcysteine	NNP
cord-344382-vge4ho2v	187	25	mucolysis	mucolysis	NN
cord-344382-vge4ho2v	187	26	in	in	IN
cord-344382-vge4ho2v	187	27	the	the	DT
cord-344382-vge4ho2v	187	28	management	management	NN
cord-344382-vge4ho2v	187	29	of	of	IN
cord-344382-vge4ho2v	187	30	chronic	chronic	JJ
cord-344382-vge4ho2v	187	31	obstructive	obstructive	JJ
cord-344382-vge4ho2v	187	32	pulmonary	pulmonary	JJ
cord-344382-vge4ho2v	187	33	disease	disease	NN
cord-344382-vge4ho2v	187	34	StatPearls	StatPearls	NNP
cord-344382-vge4ho2v	187	35	.	.	.
cord-344382-vge4ho2v	188	1	Treasure	Treasure	NNP
cord-344382-vge4ho2v	188	2	Medical	medical	JJ
cord-344382-vge4ho2v	188	3	and	and	CC
cord-344382-vge4ho2v	188	4	dietary	dietary	JJ
cord-344382-vge4ho2v	188	5	uses	use	NNS
cord-344382-vge4ho2v	188	6	of	of	IN
cord-344382-vge4ho2v	188	7	N	n	CD
cord-344382-vge4ho2v	188	8	-	-	HYPH
cord-344382-vge4ho2v	188	9	acetylcysteine	acetylcysteine	NNP
cord-344382-vge4ho2v	188	10	Mechanisms	Mechanisms	NNPS
cord-344382-vge4ho2v	188	11	of	of	IN
cord-344382-vge4ho2v	188	12	N	N	NNP
cord-344382-vge4ho2v	188	13	-	-	HYPH
cord-344382-vge4ho2v	188	14	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	188	15	in	in	IN
cord-344382-vge4ho2v	188	16	the	the	DT
cord-344382-vge4ho2v	188	17	prevention	prevention	NN
cord-344382-vge4ho2v	188	18	of	of	IN
cord-344382-vge4ho2v	188	19	DNA	dna	NN
cord-344382-vge4ho2v	188	20	damage	damage	NN
cord-344382-vge4ho2v	188	21	and	and	CC
cord-344382-vge4ho2v	188	22	cancer	cancer	NN
cord-344382-vge4ho2v	188	23	,	,	,
cord-344382-vge4ho2v	188	24	with	with	IN
cord-344382-vge4ho2v	188	25	special	special	JJ
cord-344382-vge4ho2v	188	26	reference	reference	NN
cord-344382-vge4ho2v	188	27	to	to	IN
cord-344382-vge4ho2v	188	28	smoking	smoking	NN
cord-344382-vge4ho2v	188	29	-	-	HYPH
cord-344382-vge4ho2v	188	30	related	relate	VBN
cord-344382-vge4ho2v	188	31	end	end	NN
cord-344382-vge4ho2v	188	32	-	-	HYPH
cord-344382-vge4ho2v	188	33	points	point	NNS
cord-344382-vge4ho2v	188	34	Glutathione	glutathione	NN
cord-344382-vge4ho2v	188	35	depletion	depletion	NN
cord-344382-vge4ho2v	188	36	is	be	VBZ
cord-344382-vge4ho2v	188	37	associated	associate	VBN
cord-344382-vge4ho2v	188	38	with	with	IN
cord-344382-vge4ho2v	188	39	augmenting	augment	VBG
cord-344382-vge4ho2v	188	40	a	a	DT
cord-344382-vge4ho2v	188	41	proinflammatory	proinflammatory	JJ
cord-344382-vge4ho2v	188	42	signal	signal	NN
cord-344382-vge4ho2v	188	43	:	:	:
cord-344382-vge4ho2v	188	44	evidence	evidence	NN
cord-344382-vge4ho2v	188	45	for	for	IN
cord-344382-vge4ho2v	188	46	an	an	DT
cord-344382-vge4ho2v	188	47	antioxidant	antioxidant	JJ
cord-344382-vge4ho2v	188	48	/	/	SYM
cord-344382-vge4ho2v	188	49	pro	pro	JJ
cord-344382-vge4ho2v	188	50	-	-	JJ
cord-344382-vge4ho2v	188	51	oxidant	oxidant	JJ
cord-344382-vge4ho2v	188	52	mechanism	mechanism	NN
cord-344382-vge4ho2v	188	53	regulating	regulate	VBG
cord-344382-vge4ho2v	188	54	cytokines	cytokine	NNS
cord-344382-vge4ho2v	188	55	in	in	IN
cord-344382-vge4ho2v	188	56	the	the	DT
cord-344382-vge4ho2v	188	57	alveolar	alveolar	JJ
cord-344382-vge4ho2v	188	58	epithelium	epithelium	NN
cord-344382-vge4ho2v	188	59	Role	role	NN
cord-344382-vge4ho2v	188	60	of	of	IN
cord-344382-vge4ho2v	188	61	glutathione	glutathione	NN
cord-344382-vge4ho2v	188	62	in	in	IN
cord-344382-vge4ho2v	188	63	immunity	immunity	NN
cord-344382-vge4ho2v	188	64	and	and	CC
cord-344382-vge4ho2v	188	65	inflammation	inflammation	NN
cord-344382-vge4ho2v	188	66	in	in	IN
cord-344382-vge4ho2v	188	67	the	the	DT
cord-344382-vge4ho2v	188	68	lung	lung	NN
cord-344382-vge4ho2v	188	69	New	new	JJ
cord-344382-vge4ho2v	188	70	insights	insight	NNS
cord-344382-vge4ho2v	188	71	into	into	IN
cord-344382-vge4ho2v	188	72	the	the	DT
cord-344382-vge4ho2v	188	73	role	role	NN
cord-344382-vge4ho2v	188	74	of	of	IN
cord-344382-vge4ho2v	188	75	glutathione	glutathione	NN
cord-344382-vge4ho2v	188	76	in	in	IN
cord-344382-vge4ho2v	188	77	the	the	DT
cord-344382-vge4ho2v	188	78	mechanism	mechanism	NN
cord-344382-vge4ho2v	188	79	of	of	IN
cord-344382-vge4ho2v	188	80	fever	fever	NN
cord-344382-vge4ho2v	188	81	Does	do	VBZ
cord-344382-vge4ho2v	188	82	complement	complement	VB
cord-344382-vge4ho2v	188	83	or	or	CC
cord-344382-vge4ho2v	188	84	the	the	DT
cord-344382-vge4ho2v	188	85	contact	contact	NN
cord-344382-vge4ho2v	188	86	system	system	NN
cord-344382-vge4ho2v	188	87	have	have	VBP
cord-344382-vge4ho2v	188	88	a	a	DT
cord-344382-vge4ho2v	188	89	role	role	NN
cord-344382-vge4ho2v	188	90	in	in	IN
cord-344382-vge4ho2v	188	91	protection	protection	NN
cord-344382-vge4ho2v	188	92	or	or	CC
cord-344382-vge4ho2v	188	93	pathogenesis	pathogenesis	NN
cord-344382-vge4ho2v	188	94	of	of	IN
cord-344382-vge4ho2v	188	95	COVID-19	covid-19	NN
cord-344382-vge4ho2v	188	96	?	?	.
cord-344382-vge4ho2v	189	1	Pulm	Pulm	NNP
cord-344382-vge4ho2v	189	2	Ther	Ther	NNP
cord-344382-vge4ho2v	189	3	Complement	Complement	NNP
cord-344382-vge4ho2v	189	4	activation	activation	NN
cord-344382-vge4ho2v	189	5	in	in	IN
cord-344382-vge4ho2v	189	6	patients	patient	NNS
cord-344382-vge4ho2v	189	7	with	with	IN
cord-344382-vge4ho2v	189	8	COVID-19	covid-19	CD
cord-344382-vge4ho2v	189	9	:	:	:
cord-344382-vge4ho2v	189	10	A	a	DT
cord-344382-vge4ho2v	189	11	novel	novel	JJ
cord-344382-vge4ho2v	189	12	therapeutic	therapeutic	JJ
cord-344382-vge4ho2v	189	13	target	target	NN
cord-344382-vge4ho2v	189	14	Effect	effect	NN
cord-344382-vge4ho2v	189	15	of	of	IN
cord-344382-vge4ho2v	189	16	oral	oral	JJ
cord-344382-vge4ho2v	189	17	N	n	CD
cord-344382-vge4ho2v	189	18	-	-	HYPH
cord-344382-vge4ho2v	189	19	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	189	20	treatment	treatment	NN
cord-344382-vge4ho2v	189	21	on	on	IN
cord-344382-vge4ho2v	189	22	immune	immune	JJ
cord-344382-vge4ho2v	189	23	system	system	NN
cord-344382-vge4ho2v	189	24	in	in	IN
cord-344382-vge4ho2v	189	25	continuous	continuous	JJ
cord-344382-vge4ho2v	189	26	ambulatory	ambulatory	JJ
cord-344382-vge4ho2v	189	27	peritoneal	peritoneal	JJ
cord-344382-vge4ho2v	189	28	dialysis	dialysis	NN
cord-344382-vge4ho2v	189	29	patients	patient	NNS
cord-344382-vge4ho2v	190	1	The	the	DT
cord-344382-vge4ho2v	190	2	glutathione	glutathione	NN
cord-344382-vge4ho2v	190	3	precursor	precursor	NN
cord-344382-vge4ho2v	190	4	N	n	CD
cord-344382-vge4ho2v	190	5	-	-	HYPH
cord-344382-vge4ho2v	190	6	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	190	7	improves	improve	VBZ
cord-344382-vge4ho2v	190	8	immune	immune	JJ
cord-344382-vge4ho2v	190	9	function	function	NN
cord-344382-vge4ho2v	190	10	in	in	IN
cord-344382-vge4ho2v	190	11	postmenopausal	postmenopausal	JJ
cord-344382-vge4ho2v	190	12	women	woman	NNS
cord-344382-vge4ho2v	190	13	Antioxidant	antioxidant	JJ
cord-344382-vge4ho2v	190	14	action	action	NN
cord-344382-vge4ho2v	190	15	via	via	IN
cord-344382-vge4ho2v	190	16	p53-mediated	p53-mediated	JJ
cord-344382-vge4ho2v	190	17	apoptosis	apoptosis	NN
cord-344382-vge4ho2v	190	18	N	n	CD
cord-344382-vge4ho2v	190	19	-	-	HYPH
cord-344382-vge4ho2v	190	20	Acetylcysteine	Acetylcysteine	NNP
cord-344382-vge4ho2v	190	21	as	as	IN
cord-344382-vge4ho2v	190	22	an	an	DT
cord-344382-vge4ho2v	190	23	antioxidant	antioxidant	NN
cord-344382-vge4ho2v	190	24	and	and	CC
cord-344382-vge4ho2v	190	25	disulphide	disulphide	JJ
cord-344382-vge4ho2v	190	26	breaking	breaking	NN
cord-344382-vge4ho2v	190	27	agent	agent	NN
cord-344382-vge4ho2v	190	28	:	:	:
cord-344382-vge4ho2v	190	29	the	the	DT
cord-344382-vge4ho2v	190	30	reasons	reason	NNS
cord-344382-vge4ho2v	190	31	why	why	WRB
cord-344382-vge4ho2v	190	32	The	the	DT
cord-344382-vge4ho2v	190	33	antioxidant	antioxidant	JJ
cord-344382-vge4ho2v	190	34	action	action	NN
cord-344382-vge4ho2v	190	35	of	of	IN
cord-344382-vge4ho2v	190	36	N	n	NN
cord-344382-vge4ho2v	190	37	-	-	HYPH
cord-344382-vge4ho2v	190	38	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	190	39	:	:	:
cord-344382-vge4ho2v	190	40	its	-PRON-	PRP$
cord-344382-vge4ho2v	190	41	reaction	reaction	NN
cord-344382-vge4ho2v	190	42	with	with	IN
cord-344382-vge4ho2v	190	43	hydrogen	hydrogen	NN
cord-344382-vge4ho2v	190	44	peroxide	peroxide	NN
cord-344382-vge4ho2v	190	45	,	,	,
cord-344382-vge4ho2v	190	46	hydroxyl	hydroxyl	NN
cord-344382-vge4ho2v	190	47	radical	radical	JJ
cord-344382-vge4ho2v	190	48	,	,	,
cord-344382-vge4ho2v	190	49	superoxide	superoxide	NN
cord-344382-vge4ho2v	190	50	,	,	,
cord-344382-vge4ho2v	190	51	and	and	CC
cord-344382-vge4ho2v	190	52	hypochlorous	hypochlorous	JJ
cord-344382-vge4ho2v	190	53	acid	acid	NN
cord-344382-vge4ho2v	190	54	NAD(P)H	NAD(P)H	NNP
cord-344382-vge4ho2v	190	55	oxidase	oxidase	NN
cord-344382-vge4ho2v	190	56	:	:	:
cord-344382-vge4ho2v	190	57	role	role	NN
cord-344382-vge4ho2v	190	58	in	in	IN
cord-344382-vge4ho2v	190	59	cardiovascular	cardiovascular	JJ
cord-344382-vge4ho2v	190	60	biology	biology	NN
cord-344382-vge4ho2v	190	61	and	and	CC
cord-344382-vge4ho2v	190	62	disease	disease	NN
cord-344382-vge4ho2v	190	63	Overview	Overview	NNP
cord-344382-vge4ho2v	190	64	on	on	IN
cord-344382-vge4ho2v	190	65	the	the	DT
cord-344382-vge4ho2v	190	66	effects	effect	NNS
cord-344382-vge4ho2v	190	67	of	of	IN
cord-344382-vge4ho2v	190	68	N	n	NN
cord-344382-vge4ho2v	190	69	-	-	HYPH
cord-344382-vge4ho2v	190	70	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	190	71	in	in	IN
cord-344382-vge4ho2v	190	72	neurodegenerative	neurodegenerative	JJ
cord-344382-vge4ho2v	190	73	diseases	disease	NNS
cord-344382-vge4ho2v	191	1	Nitric	nitric	NN
cord-344382-vge4ho2v	191	2	oxide	oxide	NN
cord-344382-vge4ho2v	191	3	insufficiency	insufficiency	NN
cord-344382-vge4ho2v	191	4	,	,	,
cord-344382-vge4ho2v	191	5	platelet	platelet	NN
cord-344382-vge4ho2v	191	6	activation	activation	NN
cord-344382-vge4ho2v	191	7	,	,	,
cord-344382-vge4ho2v	191	8	and	and	CC
cord-344382-vge4ho2v	191	9	arterial	arterial	JJ
cord-344382-vge4ho2v	191	10	thrombosis	thrombosis	NN
cord-344382-vge4ho2v	191	11	NAC	NAC	NNP
cord-344382-vge4ho2v	191	12	)	)	-RRB-
cord-344382-vge4ho2v	191	13	inhibits	inhibit	VBZ
cord-344382-vge4ho2v	191	14	cell	cell	NN
cord-344382-vge4ho2v	191	15	growth	growth	NN
cord-344382-vge4ho2v	191	16	by	by	IN
cord-344382-vge4ho2v	191	17	mediating	mediate	VBG
cord-344382-vge4ho2v	191	18	the	the	DT
cord-344382-vge4ho2v	191	19	EGFR	EGFR	NNP
cord-344382-vge4ho2v	191	20	/	/	SYM
cord-344382-vge4ho2v	191	21	Akt	Akt	NNP
cord-344382-vge4ho2v	191	22	/	/	SYM
cord-344382-vge4ho2v	191	23	HMG	HMG	NNP
cord-344382-vge4ho2v	191	24	box	box	NN
cord-344382-vge4ho2v	191	25	-	-	HYPH
cord-344382-vge4ho2v	191	26	containing	contain	VBG
cord-344382-vge4ho2v	191	27	protein	protein	NN
cord-344382-vge4ho2v	191	28	1	1	CD
cord-344382-vge4ho2v	192	1	(	(	-LRB-
cord-344382-vge4ho2v	192	2	HBP1	HBP1	NNP
cord-344382-vge4ho2v	192	3	)	)	-RRB-
cord-344382-vge4ho2v	192	4	signaling	signal	VBG
cord-344382-vge4ho2v	192	5	pathway	pathway	NN
cord-344382-vge4ho2v	192	6	in	in	IN
cord-344382-vge4ho2v	192	7	invasive	invasive	JJ
cord-344382-vge4ho2v	192	8	oral	oral	JJ
cord-344382-vge4ho2v	192	9	cancer	cancer	NN
cord-344382-vge4ho2v	192	10	in	in	IN
cord-344382-vge4ho2v	192	11	a	a	DT
cord-344382-vge4ho2v	192	12	mouse	mouse	NN
cord-344382-vge4ho2v	192	13	model	model	NN
cord-344382-vge4ho2v	192	14	of	of	IN
cord-344382-vge4ho2v	192	15	orthotopic	orthotopic	JJ
cord-344382-vge4ho2v	192	16	lung	lung	NNP
cord-344382-vge4ho2v	192	17	transplantation	transplantation	NN
cord-344382-vge4ho2v	192	18	Genomic	genomic	JJ
cord-344382-vge4ho2v	192	19	and	and	CC
cord-344382-vge4ho2v	192	20	transcriptional	transcriptional	JJ
cord-344382-vge4ho2v	192	21	alterations	alteration	NNS
cord-344382-vge4ho2v	192	22	in	in	IN
cord-344382-vge4ho2v	192	23	mouse	mouse	NN
cord-344382-vge4ho2v	192	24	fetus	fetus	NN
cord-344382-vge4ho2v	192	25	liver	liver	NN
cord-344382-vge4ho2v	192	26	after	after	IN
cord-344382-vge4ho2v	192	27	transplacental	transplacental	NNP
cord-344382-vge4ho2v	192	28	exposure	exposure	NN
cord-344382-vge4ho2v	192	29	to	to	IN
cord-344382-vge4ho2v	192	30	cigarette	cigarette	NN
cord-344382-vge4ho2v	192	31	smoke	smoke	NN
cord-344382-vge4ho2v	192	32	High	High	NNP
cord-344382-vge4ho2v	192	33	-	-	HYPH
cord-344382-vge4ho2v	192	34	dose	dose	NN
cord-344382-vge4ho2v	192	35	N	n	CD
cord-344382-vge4ho2v	192	36	-	-	HYPH
cord-344382-vge4ho2v	192	37	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	192	38	in	in	IN
cord-344382-vge4ho2v	192	39	patients	patient	NNS
cord-344382-vge4ho2v	192	40	with	with	IN
cord-344382-vge4ho2v	192	41	exacerbations	exacerbation	NNS
cord-344382-vge4ho2v	192	42	of	of	IN
cord-344382-vge4ho2v	192	43	chronic	chronic	JJ
cord-344382-vge4ho2v	192	44	obstructive	obstructive	JJ
cord-344382-vge4ho2v	192	45	pulmonary	pulmonary	JJ
cord-344382-vge4ho2v	192	46	disease	disease	NN
cord-344382-vge4ho2v	192	47	Effect	Effect	NNP
cord-344382-vge4ho2v	192	48	of	of	IN
cord-344382-vge4ho2v	192	49	N	N	NNP
cord-344382-vge4ho2v	192	50	-	-	HYPH
cord-344382-vge4ho2v	192	51	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	192	52	on	on	IN
cord-344382-vge4ho2v	192	53	exacerbations	exacerbation	NNS
cord-344382-vge4ho2v	192	54	of	of	IN
cord-344382-vge4ho2v	192	55	bronchiectasis	bronchiectasis	NN
cord-344382-vge4ho2v	192	56	(	(	-LRB-
cord-344382-vge4ho2v	192	57	BENE	BENE	NNP
cord-344382-vge4ho2v	192	58	)	)	-RRB-
cord-344382-vge4ho2v	192	59	:	:	:
cord-344382-vge4ho2v	192	60	a	a	DT
cord-344382-vge4ho2v	192	61	randomized	randomized	JJ
cord-344382-vge4ho2v	192	62	controlled	control	VBN
cord-344382-vge4ho2v	192	63	trial	trial	NN
cord-344382-vge4ho2v	192	64	Deficiency	deficiency	NN
cord-344382-vge4ho2v	192	65	of	of	IN
cord-344382-vge4ho2v	192	66	alveolar	alveolar	JJ
cord-344382-vge4ho2v	192	67	fluid	fluid	JJ
cord-344382-vge4ho2v	192	68	glutathione	glutathione	NN
cord-344382-vge4ho2v	192	69	in	in	IN
cord-344382-vge4ho2v	192	70	patients	patient	NNS
cord-344382-vge4ho2v	192	71	with	with	IN
cord-344382-vge4ho2v	192	72	sepsis	sepsis	NN
cord-344382-vge4ho2v	192	73	and	and	CC
cord-344382-vge4ho2v	192	74	the	the	DT
cord-344382-vge4ho2v	192	75	adult	adult	NN
cord-344382-vge4ho2v	192	76	respiratory	respiratory	JJ
cord-344382-vge4ho2v	192	77	distress	distress	NN
cord-344382-vge4ho2v	192	78	syndrome	syndrome	NN
cord-344382-vge4ho2v	193	1	A	a	DT
cord-344382-vge4ho2v	193	2	trial	trial	NN
cord-344382-vge4ho2v	193	3	of	of	IN
cord-344382-vge4ho2v	193	4	antioxidants	antioxidant	NNS
cord-344382-vge4ho2v	193	5	N	n	NN
cord-344382-vge4ho2v	193	6	-	-	HYPH
cord-344382-vge4ho2v	193	7	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	193	8	and	and	CC
cord-344382-vge4ho2v	193	9	procysteine	procysteine	NN
cord-344382-vge4ho2v	193	10	in	in	IN
cord-344382-vge4ho2v	193	11	ARDS	ARDS	NNP
cord-344382-vge4ho2v	193	12	.	.	.
cord-344382-vge4ho2v	194	1	The	the	DT
cord-344382-vge4ho2v	194	2	Antioxidant	Antioxidant	NNP
cord-344382-vge4ho2v	194	3	in	in	IN
cord-344382-vge4ho2v	194	4	ARDS	ARDS	NNP
cord-344382-vge4ho2v	194	5	Study	Study	NNP
cord-344382-vge4ho2v	194	6	Group	Group	NNP
cord-344382-vge4ho2v	194	7	Protective	protective	JJ
cord-344382-vge4ho2v	194	8	effects	effect	NNS
cord-344382-vge4ho2v	194	9	of	of	IN
cord-344382-vge4ho2v	194	10	N	n	NN
cord-344382-vge4ho2v	194	11	-	-	HYPH
cord-344382-vge4ho2v	194	12	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	194	13	and	and	CC
cord-344382-vge4ho2v	194	14	rutin	rutin	NN
cord-344382-vge4ho2v	194	15	on	on	IN
cord-344382-vge4ho2v	194	16	the	the	DT
cord-344382-vge4ho2v	194	17	lipid	lipid	NN
cord-344382-vge4ho2v	194	18	peroxidation	peroxidation	NN
cord-344382-vge4ho2v	194	19	of	of	IN
cord-344382-vge4ho2v	194	20	the	the	DT
cord-344382-vge4ho2v	194	21	lung	lung	NN
cord-344382-vge4ho2v	194	22	epithelium	epithelium	NN
cord-344382-vge4ho2v	194	23	during	during	IN
cord-344382-vge4ho2v	194	24	the	the	DT
cord-344382-vge4ho2v	194	25	adult	adult	NN
cord-344382-vge4ho2v	194	26	respiratory	respiratory	JJ
cord-344382-vge4ho2v	194	27	distress	distress	NN
cord-344382-vge4ho2v	194	28	syndrome	syndrome	NN
cord-344382-vge4ho2v	194	29	Improvement	improvement	NN
cord-344382-vge4ho2v	194	30	by	by	IN
cord-344382-vge4ho2v	194	31	N	n	NN
cord-344382-vge4ho2v	194	32	-	-	HYPH
cord-344382-vge4ho2v	194	33	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	194	34	of	of	IN
cord-344382-vge4ho2v	194	35	acute	acute	JJ
cord-344382-vge4ho2v	194	36	respiratory	respiratory	JJ
cord-344382-vge4ho2v	194	37	distress	distress	NN
cord-344382-vge4ho2v	194	38	syndrome	syndrome	NN
cord-344382-vge4ho2v	194	39	through	through	IN
cord-344382-vge4ho2v	194	40	increasing	increase	VBG
cord-344382-vge4ho2v	194	41	intracellular	intracellular	JJ
cord-344382-vge4ho2v	194	42	glutathione	glutathione	NN
cord-344382-vge4ho2v	194	43	,	,	,
cord-344382-vge4ho2v	194	44	and	and	CC
cord-344382-vge4ho2v	194	45	extracellular	extracellular	JJ
cord-344382-vge4ho2v	194	46	thiol	thiol	NN
cord-344382-vge4ho2v	194	47	molecules	molecule	NNS
cord-344382-vge4ho2v	194	48	and	and	CC
cord-344382-vge4ho2v	194	49	anti	anti	JJ
cord-344382-vge4ho2v	194	50	-	-	JJ
cord-344382-vge4ho2v	194	51	oxidant	oxidant	JJ
cord-344382-vge4ho2v	194	52	power	power	NN
cord-344382-vge4ho2v	194	53	:	:	:
cord-344382-vge4ho2v	194	54	evidence	evidence	NN
cord-344382-vge4ho2v	194	55	for	for	IN
cord-344382-vge4ho2v	194	56	underlying	underlie	VBG
cord-344382-vge4ho2v	194	57	toxicological	toxicological	JJ
cord-344382-vge4ho2v	194	58	mechanisms	mechanism	NNS
cord-344382-vge4ho2v	194	59	N	n	NN
cord-344382-vge4ho2v	194	60	-	-	HYPH
cord-344382-vge4ho2v	194	61	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	194	62	amide	amide	NN
cord-344382-vge4ho2v	194	63	provides	provide	VBZ
cord-344382-vge4ho2v	194	64	neuroprotection	neuroprotection	NN
cord-344382-vge4ho2v	194	65	via	via	IN
cord-344382-vge4ho2v	194	66	Nrf2-ARE	Nrf2-ARE	NNP
cord-344382-vge4ho2v	194	67	pathway	pathway	NN
cord-344382-vge4ho2v	194	68	in	in	IN
cord-344382-vge4ho2v	194	69	a	a	DT
cord-344382-vge4ho2v	194	70	mouse	mouse	NN
cord-344382-vge4ho2v	194	71	model	model	NN
cord-344382-vge4ho2v	194	72	of	of	IN
cord-344382-vge4ho2v	194	73	traumatic	traumatic	JJ
cord-344382-vge4ho2v	194	74	brain	brain	NN
cord-344382-vge4ho2v	194	75	injury	injury	NN
cord-344382-vge4ho2v	195	1	Targeting	target	VBG
cord-344382-vge4ho2v	196	1	Nrf-2	Nrf-2	NNP
cord-344382-vge4ho2v	196	2	is	be	VBZ
cord-344382-vge4ho2v	196	3	a	a	DT
cord-344382-vge4ho2v	196	4	promising	promising	JJ
cord-344382-vge4ho2v	196	5	intervention	intervention	NN
cord-344382-vge4ho2v	196	6	approach	approach	NN
cord-344382-vge4ho2v	196	7	for	for	IN
cord-344382-vge4ho2v	196	8	the	the	DT
cord-344382-vge4ho2v	196	9	prevention	prevention	NN
cord-344382-vge4ho2v	196	10	of	of	IN
cord-344382-vge4ho2v	196	11	ethanol	ethanol	NN
cord-344382-vge4ho2v	196	12	-	-	HYPH
cord-344382-vge4ho2v	196	13	induced	induce	VBN
cord-344382-vge4ho2v	196	14	liver	liver	NN
cord-344382-vge4ho2v	196	15	disease	disease	NN
cord-344382-vge4ho2v	196	16	Targeting	target	VBG
cord-344382-vge4ho2v	196	17	the	the	DT
cord-344382-vge4ho2v	196	18	heme	heme	JJ
cord-344382-vge4ho2v	196	19	-	-	HYPH
cord-344382-vge4ho2v	196	20	heme	heme	JJ
cord-344382-vge4ho2v	196	21	oxygenase	oxygenase	NN
cord-344382-vge4ho2v	196	22	system	system	NN
cord-344382-vge4ho2v	196	23	to	to	TO
cord-344382-vge4ho2v	196	24	prevent	prevent	VB
cord-344382-vge4ho2v	196	25	severe	severe	JJ
cord-344382-vge4ho2v	196	26	complications	complication	NNS
cord-344382-vge4ho2v	196	27	following	follow	VBG
cord-344382-vge4ho2v	196	28	COVID-19	covid-19	CD
cord-344382-vge4ho2v	196	29	infections	infection	NNS
cord-344382-vge4ho2v	196	30	Adjunctive	Adjunctive	NNP
cord-344382-vge4ho2v	196	31	therapies	therapy	NNS
cord-344382-vge4ho2v	196	32	and	and	CC
cord-344382-vge4ho2v	196	33	immunomodulating	immunomodulate	VBG
cord-344382-vge4ho2v	196	34	agents	agent	NNS
cord-344382-vge4ho2v	196	35	for	for	IN
cord-344382-vge4ho2v	196	36	severe	severe	JJ
cord-344382-vge4ho2v	196	37	influenza	influenza	NN
cord-344382-vge4ho2v	196	38	.	.	.
cord-344382-vge4ho2v	197	1	Influenza	Influenza	NNP
cord-344382-vge4ho2v	197	2	Other	other	JJ
cord-344382-vge4ho2v	197	3	Respir	Respir	NNP
cord-344382-vge4ho2v	197	4	Viruses	virus	NNS
cord-344382-vge4ho2v	198	1	The	the	DT
cord-344382-vge4ho2v	198	2	W	w	NN
cord-344382-vge4ho2v	198	3	-	-	HYPH
cord-344382-vge4ho2v	198	4	shaped	shape	VBN
cord-344382-vge4ho2v	198	5	mortality	mortality	NN
cord-344382-vge4ho2v	198	6	-	-	HYPH
cord-344382-vge4ho2v	198	7	age	age	NN
cord-344382-vge4ho2v	198	8	distribution	distribution	NN
cord-344382-vge4ho2v	198	9	of	of	IN
cord-344382-vge4ho2v	198	10	novel	novel	NN
cord-344382-vge4ho2v	198	11	H1N1	H1N1	NNP
cord-344382-vge4ho2v	198	12	influenza	influenza	NN
cord-344382-vge4ho2v	198	13	virus	virus	NN
cord-344382-vge4ho2v	198	14	helps	help	VBZ
cord-344382-vge4ho2v	198	15	reconstruct	reconstruct	VB
cord-344382-vge4ho2v	198	16	the	the	DT
cord-344382-vge4ho2v	198	17	second	second	JJ
cord-344382-vge4ho2v	198	18	wave	wave	NN
cord-344382-vge4ho2v	198	19	of	of	IN
cord-344382-vge4ho2v	198	20	pandemic	pandemic	NN
cord-344382-vge4ho2v	198	21	1918	1918	CD
cord-344382-vge4ho2v	198	22	Spanish	spanish	JJ
cord-344382-vge4ho2v	198	23	flu	flu	NN
cord-344382-vge4ho2v	198	24	Multifaceted	multifaceted	JJ
cord-344382-vge4ho2v	198	25	activity	activity	NN
cord-344382-vge4ho2v	198	26	of	of	IN
cord-344382-vge4ho2v	198	27	N	n	NN
cord-344382-vge4ho2v	198	28	-	-	HYPH
cord-344382-vge4ho2v	198	29	acetyl	acetyl	NNP
cord-344382-vge4ho2v	198	30	-	-	HYPH
cord-344382-vge4ho2v	198	31	l	l	NN
cord-344382-vge4ho2v	198	32	-	-	HYPH
cord-344382-vge4ho2v	198	33	cysteine	cysteine	NN
cord-344382-vge4ho2v	198	34	in	in	IN
cord-344382-vge4ho2v	198	35	chronic	chronic	JJ
cord-344382-vge4ho2v	198	36	obstructive	obstructive	JJ
cord-344382-vge4ho2v	198	37	pulmonary	pulmonary	JJ
cord-344382-vge4ho2v	198	38	disease	disease	NN
cord-344382-vge4ho2v	199	1	The	the	DT
cord-344382-vge4ho2v	199	2	N	N	NNP
cord-344382-vge4ho2v	199	3	-	-	HYPH
cord-344382-vge4ho2v	199	4	AcetylCysteine	AcetylCysteine	NNP
cord-344382-vge4ho2v	199	5	and	and	CC
cord-344382-vge4ho2v	199	6	RAMipril	RAMipril	NNP
cord-344382-vge4ho2v	199	7	in	in	IN
cord-344382-vge4ho2v	199	8	Takotsubo	Takotsubo	NNP
cord-344382-vge4ho2v	199	9	Syndrome	Syndrome	NNP
cord-344382-vge4ho2v	199	10	Trial	Trial	NNP
cord-344382-vge4ho2v	199	11	(	(	-LRB-
cord-344382-vge4ho2v	199	12	NACRAM	NACRAM	NNP
cord-344382-vge4ho2v	199	13	)	)	-RRB-
cord-344382-vge4ho2v	199	14	:	:	:
cord-344382-vge4ho2v	200	1	Rationale	rationale	NN
cord-344382-vge4ho2v	200	2	and	and	CC
cord-344382-vge4ho2v	200	3	design	design	NN
cord-344382-vge4ho2v	200	4	of	of	IN
cord-344382-vge4ho2v	200	5	a	a	DT
cord-344382-vge4ho2v	200	6	randomised	randomised	JJ
cord-344382-vge4ho2v	200	7	controlled	control	VBN
cord-344382-vge4ho2v	200	8	trial	trial	NN
cord-344382-vge4ho2v	200	9	of	of	IN
cord-344382-vge4ho2v	200	10	sequential	sequential	JJ
cord-344382-vge4ho2v	200	11	N	n	CD
cord-344382-vge4ho2v	200	12	-	-	HYPH
cord-344382-vge4ho2v	200	13	Acetylcysteine	Acetylcysteine	NNP
cord-344382-vge4ho2v	200	14	and	and	CC
cord-344382-vge4ho2v	200	15	ramipril	ramipril	NN
cord-344382-vge4ho2v	200	16	for	for	IN
cord-344382-vge4ho2v	200	17	the	the	DT
cord-344382-vge4ho2v	200	18	management	management	NN
cord-344382-vge4ho2v	200	19	of	of	IN
cord-344382-vge4ho2v	200	20	Takotsubo	Takotsubo	NNP
cord-344382-vge4ho2v	200	21	Syndrome	Syndrome	NNP
cord-344382-vge4ho2v	200	22	Attenuation	Attenuation	NNP
cord-344382-vge4ho2v	200	23	of	of	IN
cord-344382-vge4ho2v	200	24	influenza	influenza	NN
cord-344382-vge4ho2v	200	25	-	-	HYPH
cord-344382-vge4ho2v	200	26	like	like	JJ
cord-344382-vge4ho2v	200	27	symptomatology	symptomatology	NN
cord-344382-vge4ho2v	200	28	and	and	CC
cord-344382-vge4ho2v	200	29	improvement	improvement	NN
cord-344382-vge4ho2v	200	30	of	of	IN
cord-344382-vge4ho2v	200	31	cell	cell	NN
cord-344382-vge4ho2v	200	32	-	-	HYPH
cord-344382-vge4ho2v	200	33	mediated	mediate	VBN
cord-344382-vge4ho2v	200	34	immunity	immunity	NN
cord-344382-vge4ho2v	200	35	with	with	IN
cord-344382-vge4ho2v	200	36	longterm	longterm	JJ
cord-344382-vge4ho2v	200	37	N	n	NN
cord-344382-vge4ho2v	200	38	-	-	HYPH
cord-344382-vge4ho2v	200	39	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	200	40	treatment	treatment	NN
cord-344382-vge4ho2v	200	41	Influenza	Influenza	NNP
cord-344382-vge4ho2v	200	42	A	a	DT
cord-344382-vge4ho2v	200	43	virus	virus	NN
cord-344382-vge4ho2v	200	44	replication	replication	NN
cord-344382-vge4ho2v	200	45	is	be	VBZ
cord-344382-vge4ho2v	200	46	dependent	dependent	JJ
cord-344382-vge4ho2v	200	47	on	on	IN
cord-344382-vge4ho2v	200	48	an	an	DT
cord-344382-vge4ho2v	200	49	antioxidant	antioxidant	JJ
cord-344382-vge4ho2v	200	50	pathway	pathway	NN
cord-344382-vge4ho2v	200	51	that	that	WDT
cord-344382-vge4ho2v	200	52	involves	involve	VBZ
cord-344382-vge4ho2v	200	53	GSH	GSH	NNP
cord-344382-vge4ho2v	200	54	and	and	CC
cord-344382-vge4ho2v	200	55	Bcl-2	Bcl-2	NNP
cord-344382-vge4ho2v	200	56	Inhibition	Inhibition	NNP
cord-344382-vge4ho2v	200	57	of	of	IN
cord-344382-vge4ho2v	200	58	influenza	influenza	NN
cord-344382-vge4ho2v	200	59	infection	infection	NN
cord-344382-vge4ho2v	200	60	by	by	IN
cord-344382-vge4ho2v	200	61	glutathione	glutathione	NN
cord-344382-vge4ho2v	200	62	N	n	NN
cord-344382-vge4ho2v	200	63	-	-	HYPH
cord-344382-vge4ho2v	200	64	acetyl	acetyl	NNP
cord-344382-vge4ho2v	200	65	-	-	HYPH
cord-344382-vge4ho2v	200	66	L	l	NN
cord-344382-vge4ho2v	200	67	-	-	HYPH
cord-344382-vge4ho2v	200	68	cysteine	cysteine	NN
cord-344382-vge4ho2v	200	69	(	(	-LRB-
cord-344382-vge4ho2v	200	70	NAC	NAC	NNP
cord-344382-vge4ho2v	200	71	)	)	-RRB-
cord-344382-vge4ho2v	201	1	inhibits	inhibit	VBZ
cord-344382-vge4ho2v	201	2	virus	virus	NN
cord-344382-vge4ho2v	201	3	replication	replication	NN
cord-344382-vge4ho2v	201	4	and	and	CC
cord-344382-vge4ho2v	201	5	expression	expression	NN
cord-344382-vge4ho2v	201	6	of	of	IN
cord-344382-vge4ho2v	201	7	pro	pro	JJ
cord-344382-vge4ho2v	201	8	-	-	JJ
cord-344382-vge4ho2v	201	9	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	201	10	molecules	molecule	NNS
cord-344382-vge4ho2v	201	11	in	in	IN
cord-344382-vge4ho2v	201	12	A549	a549	JJ
cord-344382-vge4ho2v	201	13	cells	cell	NNS
cord-344382-vge4ho2v	201	14	infected	infect	VBN
cord-344382-vge4ho2v	201	15	with	with	IN
cord-344382-vge4ho2v	201	16	highly	highly	RB
cord-344382-vge4ho2v	201	17	pathogenic	pathogenic	JJ
cord-344382-vge4ho2v	201	18	H5N1	H5N1	NNP
cord-344382-vge4ho2v	201	19	influenza	influenza	NN
cord-344382-vge4ho2v	201	20	A	a	DT
cord-344382-vge4ho2v	201	21	virus	virus	NN
cord-344382-vge4ho2v	201	22	N	n	CD
cord-344382-vge4ho2v	201	23	-	-	HYPH
cord-344382-vge4ho2v	201	24	acetyl	acetyl	NNP
cord-344382-vge4ho2v	201	25	-	-	HYPH
cord-344382-vge4ho2v	201	26	l	l	NN
cord-344382-vge4ho2v	201	27	-	-	HYPH
cord-344382-vge4ho2v	201	28	cystine	cystine	NN
cord-344382-vge4ho2v	201	29	(	(	-LRB-
cord-344382-vge4ho2v	201	30	NAC	NAC	NNP
cord-344382-vge4ho2v	201	31	)	)	-RRB-
cord-344382-vge4ho2v	201	32	protects	protect	VBZ
cord-344382-vge4ho2v	201	33	against	against	IN
cord-344382-vge4ho2v	201	34	H9N2	H9N2	NNP
cord-344382-vge4ho2v	201	35	swine	swine	NN
cord-344382-vge4ho2v	201	36	influenza	influenza	NN
cord-344382-vge4ho2v	201	37	virus	virus	NN
cord-344382-vge4ho2v	201	38	-	-	HYPH
cord-344382-vge4ho2v	201	39	induced	induce	VBN
cord-344382-vge4ho2v	201	40	acute	acute	JJ
cord-344382-vge4ho2v	201	41	lung	lung	NN
cord-344382-vge4ho2v	201	42	injury	injury	NN
cord-344382-vge4ho2v	201	43	Glutathione	glutathione	NN
cord-344382-vge4ho2v	201	44	increase	increase	NN
cord-344382-vge4ho2v	201	45	by	by	IN
cord-344382-vge4ho2v	201	46	the	the	DT
cord-344382-vge4ho2v	201	47	n	n	NNP
cord-344382-vge4ho2v	201	48	-	-	HYPH
cord-344382-vge4ho2v	201	49	butanoyl	butanoyl	NNP
cord-344382-vge4ho2v	201	50	glutathione	glutathione	NN
cord-344382-vge4ho2v	201	51	derivative	derivative	NN
cord-344382-vge4ho2v	201	52	(	(	-LRB-
cord-344382-vge4ho2v	201	53	GSH	GSH	NNP
cord-344382-vge4ho2v	201	54	-	-	HYPH
cord-344382-vge4ho2v	201	55	C4	C4	NNP
cord-344382-vge4ho2v	201	56	)	)	-RRB-
cord-344382-vge4ho2v	201	57	inhibits	inhibit	VBZ
cord-344382-vge4ho2v	201	58	viral	viral	JJ
cord-344382-vge4ho2v	201	59	replication	replication	NN
cord-344382-vge4ho2v	201	60	and	and	CC
cord-344382-vge4ho2v	201	61	induces	induce	VBZ
cord-344382-vge4ho2v	201	62	a	a	DT
cord-344382-vge4ho2v	201	63	predominant	predominant	JJ
cord-344382-vge4ho2v	201	64	Th1	th1	CD
cord-344382-vge4ho2v	201	65	immune	immune	NN
cord-344382-vge4ho2v	201	66	profile	profile	NN
cord-344382-vge4ho2v	201	67	in	in	IN
cord-344382-vge4ho2v	201	68	old	old	JJ
cord-344382-vge4ho2v	201	69	mice	mouse	NNS
cord-344382-vge4ho2v	201	70	infected	infect	VBN
cord-344382-vge4ho2v	201	71	with	with	IN
cord-344382-vge4ho2v	201	72	influenza	influenza	NN
cord-344382-vge4ho2v	201	73	virus	virus	NN
cord-344382-vge4ho2v	201	74	N	n	CD
cord-344382-vge4ho2v	201	75	-	-	HYPH
cord-344382-vge4ho2v	201	76	acetyl	acetyl	NNP
cord-344382-vge4ho2v	201	77	-	-	HYPH
cord-344382-vge4ho2v	201	78	L	l	NN
cord-344382-vge4ho2v	201	79	-	-	HYPH
cord-344382-vge4ho2v	201	80	cysteine	cysteine	NN
cord-344382-vge4ho2v	201	81	(	(	-LRB-
cord-344382-vge4ho2v	201	82	NAC	NAC	NNP
cord-344382-vge4ho2v	201	83	)	)	-RRB-
cord-344382-vge4ho2v	201	84	inhibit	inhibit	VBP
cord-344382-vge4ho2v	201	85	mucin	mucin	NN
cord-344382-vge4ho2v	201	86	synthesis	synthesis	NN
cord-344382-vge4ho2v	201	87	and	and	CC
cord-344382-vge4ho2v	201	88	pro	pro	JJ
cord-344382-vge4ho2v	201	89	-	-	JJ
cord-344382-vge4ho2v	201	90	inflammatory	inflammatory	JJ
cord-344382-vge4ho2v	201	91	mediators	mediator	NNS
cord-344382-vge4ho2v	201	92	in	in	IN
cord-344382-vge4ho2v	201	93	alveolar	alveolar	JJ
cord-344382-vge4ho2v	201	94	type	type	NN
cord-344382-vge4ho2v	201	95	II	ii	CD
cord-344382-vge4ho2v	201	96	epithelial	epithelial	JJ
cord-344382-vge4ho2v	201	97	cells	cell	NNS
cord-344382-vge4ho2v	201	98	infected	infect	VBN
cord-344382-vge4ho2v	201	99	with	with	IN
cord-344382-vge4ho2v	201	100	influenza	influenza	NN
cord-344382-vge4ho2v	201	101	virus	virus	NN
cord-344382-vge4ho2v	201	102	A	a	NN
cord-344382-vge4ho2v	201	103	and	and	CC
cord-344382-vge4ho2v	201	104	B	b	NN
cord-344382-vge4ho2v	201	105	and	and	CC
cord-344382-vge4ho2v	201	106	with	with	IN
cord-344382-vge4ho2v	201	107	respiratory	respiratory	JJ
cord-344382-vge4ho2v	201	108	syncytial	syncytial	JJ
cord-344382-vge4ho2v	201	109	virus	virus	NN
cord-344382-vge4ho2v	201	110	(	(	-LRB-
cord-344382-vge4ho2v	201	111	RSV	RSV	NNP
cord-344382-vge4ho2v	201	112	)	)	-RRB-
cord-344382-vge4ho2v	202	1	Glutathione	glutathione	NN
cord-344382-vge4ho2v	202	2	inhibits	inhibit	VBZ
cord-344382-vge4ho2v	202	3	HIV	HIV	NNP
cord-344382-vge4ho2v	202	4	replication	replication	NN
cord-344382-vge4ho2v	202	5	by	by	IN
cord-344382-vge4ho2v	202	6	acting	act	VBG
cord-344382-vge4ho2v	202	7	at	at	IN
cord-344382-vge4ho2v	202	8	late	late	JJ
cord-344382-vge4ho2v	202	9	stages	stage	NNS
cord-344382-vge4ho2v	202	10	of	of	IN
cord-344382-vge4ho2v	202	11	the	the	DT
cord-344382-vge4ho2v	202	12	virus	virus	NN
cord-344382-vge4ho2v	202	13	life	life	NN
cord-344382-vge4ho2v	202	14	cycle	cycle	NN
cord-344382-vge4ho2v	202	15	Glutathione	Glutathione	NNP
cord-344382-vge4ho2v	202	16	and	and	CC
cord-344382-vge4ho2v	202	17	N	n	CD
cord-344382-vge4ho2v	202	18	-	-	HYPH
cord-344382-vge4ho2v	202	19	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	202	20	suppression	suppression	NN
cord-344382-vge4ho2v	202	21	of	of	IN
cord-344382-vge4ho2v	202	22	human	human	JJ
cord-344382-vge4ho2v	202	23	immunodeficiency	immunodeficiency	NN
cord-344382-vge4ho2v	202	24	virus	virus	NN
cord-344382-vge4ho2v	202	25	replication	replication	NN
cord-344382-vge4ho2v	202	26	in	in	IN
cord-344382-vge4ho2v	202	27	human	human	JJ
cord-344382-vge4ho2v	202	28	monocyte	monocyte	NNP
cord-344382-vge4ho2v	202	29	/	/	SYM
cord-344382-vge4ho2v	202	30	macrophages	macrophage	NNS
cord-344382-vge4ho2v	202	31	in	in	IN
cord-344382-vge4ho2v	202	32	vitro	vitro	FW
cord-344382-vge4ho2v	202	33	Synergistic	synergistic	JJ
cord-344382-vge4ho2v	202	34	combination	combination	NN
cord-344382-vge4ho2v	202	35	of	of	IN
cord-344382-vge4ho2v	202	36	N	n	NN
cord-344382-vge4ho2v	202	37	-	-	HYPH
cord-344382-vge4ho2v	202	38	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	202	39	and	and	CC
cord-344382-vge4ho2v	202	40	ribavirin	ribavirin	NN
cord-344382-vge4ho2v	202	41	to	to	TO
cord-344382-vge4ho2v	202	42	protect	protect	VB
cord-344382-vge4ho2v	202	43	from	from	IN
cord-344382-vge4ho2v	202	44	lethal	lethal	JJ
cord-344382-vge4ho2v	202	45	influenza	influenza	NN
cord-344382-vge4ho2v	202	46	viral	viral	JJ
cord-344382-vge4ho2v	202	47	infection	infection	NN
cord-344382-vge4ho2v	202	48	in	in	IN
cord-344382-vge4ho2v	202	49	a	a	DT
cord-344382-vge4ho2v	202	50	mouse	mouse	NN
cord-344382-vge4ho2v	202	51	model	model	NN
cord-344382-vge4ho2v	202	52	N	n	NN
cord-344382-vge4ho2v	202	53	-	-	HYPH
cord-344382-vge4ho2v	202	54	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	202	55	synergizes	synergize	VBZ
cord-344382-vge4ho2v	202	56	with	with	IN
cord-344382-vge4ho2v	202	57	oseltamivir	oseltamivir	NNS
cord-344382-vge4ho2v	202	58	in	in	IN
cord-344382-vge4ho2v	202	59	protecting	protect	VBG
cord-344382-vge4ho2v	202	60	mice	mouse	NNS
cord-344382-vge4ho2v	202	61	from	from	IN
cord-344382-vge4ho2v	202	62	lethal	lethal	JJ
cord-344382-vge4ho2v	202	63	influenza	influenza	NN
cord-344382-vge4ho2v	202	64	infection	infection	NN
cord-344382-vge4ho2v	202	65	COVID-19	covid-19	NN
cord-344382-vge4ho2v	202	66	and	and	CC
cord-344382-vge4ho2v	202	67	smoking	smoking	NN
cord-344382-vge4ho2v	202	68	:	:	:
cord-344382-vge4ho2v	202	69	a	a	DT
cord-344382-vge4ho2v	202	70	systematic	systematic	JJ
cord-344382-vge4ho2v	202	71	review	review	NN
cord-344382-vge4ho2v	202	72	of	of	IN
cord-344382-vge4ho2v	202	73	the	the	DT
cord-344382-vge4ho2v	202	74	evidence	evidence	NN
cord-344382-vge4ho2v	202	75	Short	Short	NNP
cord-344382-vge4ho2v	202	76	-	-	:
cord-344382-vge4ho2v	202	77	and	and	CC
cord-344382-vge4ho2v	202	78	long	long	JJ
cord-344382-vge4ho2v	202	79	-	-	HYPH
cord-344382-vge4ho2v	202	80	term	term	NN
cord-344382-vge4ho2v	202	81	effects	effect	NNS
cord-344382-vge4ho2v	202	82	of	of	IN
cord-344382-vge4ho2v	202	83	cigarette	cigarette	NN
cord-344382-vge4ho2v	202	84	smoke	smoke	NN
cord-344382-vge4ho2v	202	85	exposure	exposure	NN
cord-344382-vge4ho2v	202	86	on	on	IN
cord-344382-vge4ho2v	202	87	glutathione	glutathione	NN
cord-344382-vge4ho2v	202	88	homeostasis	homeostasis	NN
cord-344382-vge4ho2v	202	89	in	in	IN
cord-344382-vge4ho2v	202	90	human	human	JJ
cord-344382-vge4ho2v	202	91	bronchial	bronchial	JJ
cord-344382-vge4ho2v	202	92	epithelial	epithelial	JJ
cord-344382-vge4ho2v	202	93	cells	cell	NNS
cord-344382-vge4ho2v	202	94	Cigarette	cigarette	NN
cord-344382-vge4ho2v	202	95	smoke	smoke	NN
cord-344382-vge4ho2v	202	96	irreversibly	irreversibly	RB
cord-344382-vge4ho2v	202	97	modifies	modify	VBZ
cord-344382-vge4ho2v	202	98	glutathione	glutathione	NN
cord-344382-vge4ho2v	202	99	in	in	IN
cord-344382-vge4ho2v	202	100	airway	airway	NN
cord-344382-vge4ho2v	202	101	epithelial	epithelial	JJ
cord-344382-vge4ho2v	202	102	cells	cell	NNS
cord-344382-vge4ho2v	202	103	Glutathione	glutathione	NN
cord-344382-vge4ho2v	202	104	depletion	depletion	NN
cord-344382-vge4ho2v	202	105	accelerates	accelerate	VBZ
cord-344382-vge4ho2v	202	106	cigarette	cigarette	NN
cord-344382-vge4ho2v	202	107	smoke	smoke	NN
cord-344382-vge4ho2v	202	108	-	-	HYPH
cord-344382-vge4ho2v	202	109	induced	induce	VBN
cord-344382-vge4ho2v	202	110	inflammation	inflammation	NN
cord-344382-vge4ho2v	202	111	and	and	CC
cord-344382-vge4ho2v	202	112	airspace	airspace	NN
cord-344382-vge4ho2v	202	113	enlargement	enlargement	NN
cord-344382-vge4ho2v	202	114	Prevention	Prevention	NNP
cord-344382-vge4ho2v	202	115	of	of	IN
cord-344382-vge4ho2v	202	116	cigarette	cigarette	NN
cord-344382-vge4ho2v	202	117	smoke	smoke	NN
cord-344382-vge4ho2v	202	118	-	-	HYPH
cord-344382-vge4ho2v	202	119	induced	induce	VBN
cord-344382-vge4ho2v	202	120	lung	lung	NN
cord-344382-vge4ho2v	202	121	tumors	tumor	NNS
cord-344382-vge4ho2v	202	122	in	in	IN
cord-344382-vge4ho2v	202	123	mice	mouse	NNS
cord-344382-vge4ho2v	202	124	by	by	IN
cord-344382-vge4ho2v	202	125	|	|	NNP
cord-344382-vge4ho2v	202	126	9	9	CD
cord-344382-vge4ho2v	202	127	Effects	effect	NNS
cord-344382-vge4ho2v	202	128	of	of	IN
cord-344382-vge4ho2v	202	129	oral	oral	JJ
cord-344382-vge4ho2v	202	130	administration	administration	NN
cord-344382-vge4ho2v	202	131	of	of	IN
cord-344382-vge4ho2v	202	132	N	N	NNP
cord-344382-vge4ho2v	202	133	-	-	HYPH
cord-344382-vge4ho2v	202	134	acetyl	acetyl	NNP
cord-344382-vge4ho2v	202	135	-	-	HYPH
cord-344382-vge4ho2v	202	136	L	l	NN
cord-344382-vge4ho2v	202	137	-	-	HYPH
cord-344382-vge4ho2v	202	138	cysteine	cysteine	NN
cord-344382-vge4ho2v	202	139	:	:	:
cord-344382-vge4ho2v	202	140	a	a	DT
cord-344382-vge4ho2v	202	141	multi	multi	JJ
cord-344382-vge4ho2v	202	142	-	-	JJ
cord-344382-vge4ho2v	202	143	biomarker	biomarker	JJ
cord-344382-vge4ho2v	202	144	study	study	NN
cord-344382-vge4ho2v	202	145	in	in	IN
cord-344382-vge4ho2v	202	146	smokers	smoker	NNS
cord-344382-vge4ho2v	203	1	Nutraceuticals	nutraceutical	NNS
cord-344382-vge4ho2v	203	2	have	have	VBP
cord-344382-vge4ho2v	203	3	potential	potential	NN
cord-344382-vge4ho2v	203	4	for	for	IN
cord-344382-vge4ho2v	203	5	boosting	boost	VBG
cord-344382-vge4ho2v	203	6	the	the	DT
cord-344382-vge4ho2v	203	7	type	type	NN
cord-344382-vge4ho2v	203	8	1	1	CD
cord-344382-vge4ho2v	203	9	interferon	interferon	NN
cord-344382-vge4ho2v	203	10	response	response	NN
cord-344382-vge4ho2v	203	11	to	to	IN
cord-344382-vge4ho2v	203	12	RNA	RNA	NNP
cord-344382-vge4ho2v	203	13	viruses	virus	NNS
cord-344382-vge4ho2v	203	14	including	include	VBG
cord-344382-vge4ho2v	203	15	influenza	influenza	NN
cord-344382-vge4ho2v	203	16	and	and	CC
cord-344382-vge4ho2v	203	17	coronavirus	coronavirus	NN
cord-344382-vge4ho2v	204	1	What	what	WP
cord-344382-vge4ho2v	204	2	is	be	VBZ
cord-344382-vge4ho2v	204	3	the	the	DT
cord-344382-vge4ho2v	204	4	role	role	NN
cord-344382-vge4ho2v	204	5	of	of	IN
cord-344382-vge4ho2v	204	6	supplementation	supplementation	NN
cord-344382-vge4ho2v	204	7	with	with	IN
cord-344382-vge4ho2v	204	8	ascorbic	ascorbic	NN
cord-344382-vge4ho2v	204	9	acid	acid	NN
cord-344382-vge4ho2v	204	10	,	,	,
cord-344382-vge4ho2v	204	11	zinc	zinc	NN
cord-344382-vge4ho2v	204	12	,	,	,
cord-344382-vge4ho2v	204	13	vitamin	vitamin	NN
cord-344382-vge4ho2v	204	14	D	d	NN
cord-344382-vge4ho2v	204	15	,	,	,
cord-344382-vge4ho2v	204	16	or	or	CC
cord-344382-vge4ho2v	204	17	N	n	NN
cord-344382-vge4ho2v	204	18	-	-	HYPH
cord-344382-vge4ho2v	204	19	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	204	20	for	for	IN
cord-344382-vge4ho2v	204	21	prevention	prevention	NN
cord-344382-vge4ho2v	204	22	or	or	CC
cord-344382-vge4ho2v	204	23	treatment	treatment	NN
cord-344382-vge4ho2v	204	24	of	of	IN
cord-344382-vge4ho2v	204	25	COVID-19	covid-19	NN
cord-344382-vge4ho2v	204	26	?	?	.
cord-344382-vge4ho2v	205	1	Harnessing	harness	VBG
cord-344382-vge4ho2v	205	2	adenosine	adenosine	NN
cord-344382-vge4ho2v	205	3	A2A	a2a	NN
cord-344382-vge4ho2v	205	4	receptors	receptor	NNS
cord-344382-vge4ho2v	205	5	as	as	IN
cord-344382-vge4ho2v	205	6	a	a	DT
cord-344382-vge4ho2v	205	7	strategy	strategy	NN
cord-344382-vge4ho2v	205	8	for	for	IN
cord-344382-vge4ho2v	205	9	suppressing	suppress	VBG
cord-344382-vge4ho2v	205	10	the	the	DT
cord-344382-vge4ho2v	205	11	lung	lung	NN
cord-344382-vge4ho2v	205	12	inflammation	inflammation	NN
cord-344382-vge4ho2v	205	13	and	and	CC
cord-344382-vge4ho2v	205	14	thrombotic	thrombotic	JJ
cord-344382-vge4ho2v	205	15	complications	complication	NNS
cord-344382-vge4ho2v	205	16	of	of	IN
cord-344382-vge4ho2v	205	17	COVID-19	covid-19	CD
cord-344382-vge4ho2v	205	18	:	:	:
cord-344382-vge4ho2v	205	19	Potential	potential	NN
cord-344382-vge4ho2v	205	20	of	of	IN
cord-344382-vge4ho2v	205	21	pentoxifylline	pentoxifylline	NNP
cord-344382-vge4ho2v	205	22	and	and	CC
cord-344382-vge4ho2v	205	23	dipyridamole	dipyridamole	NNP
cord-344382-vge4ho2v	205	24	.	.	.
cord-344382-vge4ho2v	206	1	Med	Med	NNP
cord-344382-vge4ho2v	206	2	Hypotheses	Hypotheses	NNP
cord-344382-vge4ho2v	206	3	Treatments	treatment	NNS
cord-344382-vge4ho2v	206	4	administered	administer	VBN
cord-344382-vge4ho2v	206	5	to	to	IN
cord-344382-vge4ho2v	206	6	the	the	DT
cord-344382-vge4ho2v	206	7	first	first	JJ
cord-344382-vge4ho2v	206	8	9152	9152	CD
cord-344382-vge4ho2v	206	9	reported	report	VBN
cord-344382-vge4ho2v	206	10	cases	case	NNS
cord-344382-vge4ho2v	206	11	of	of	IN
cord-344382-vge4ho2v	206	12	COVID-19	covid-19	NN
cord-344382-vge4ho2v	206	13	:	:	:
cord-344382-vge4ho2v	207	1	A	a	DT
cord-344382-vge4ho2v	207	2	systematic	systematic	JJ
cord-344382-vge4ho2v	207	3	review	review	NN
cord-344382-vge4ho2v	207	4	Use	Use	NNP
cord-344382-vge4ho2v	207	5	of	of	IN
cord-344382-vge4ho2v	207	6	N	n	NN
cord-344382-vge4ho2v	207	7	-	-	HYPH
cord-344382-vge4ho2v	207	8	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	207	9	in	in	IN
cord-344382-vge4ho2v	207	10	the	the	DT
cord-344382-vge4ho2v	207	11	management	management	NN
cord-344382-vge4ho2v	207	12	of	of	IN
cord-344382-vge4ho2v	207	13	coronary	coronary	JJ
cord-344382-vge4ho2v	207	14	artery	artery	NN
cord-344382-vge4ho2v	207	15	diseases	disease	NNS
cord-344382-vge4ho2v	208	1	Early	early	JJ
cord-344382-vge4ho2v	208	2	use	use	NN
cord-344382-vge4ho2v	208	3	of	of	IN
cord-344382-vge4ho2v	208	4	N	n	NN
cord-344382-vge4ho2v	208	5	-	-	HYPH
cord-344382-vge4ho2v	208	6	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	208	7	with	with	IN
cord-344382-vge4ho2v	208	8	nitrate	nitrate	NN
cord-344382-vge4ho2v	208	9	therapy	therapy	NN
cord-344382-vge4ho2v	208	10	in	in	IN
cord-344382-vge4ho2v	208	11	patients	patient	NNS
cord-344382-vge4ho2v	208	12	undergoing	undergo	VBG
cord-344382-vge4ho2v	208	13	primary	primary	JJ
cord-344382-vge4ho2v	208	14	percutaneous	percutaneous	JJ
cord-344382-vge4ho2v	208	15	coronary	coronary	NN
cord-344382-vge4ho2v	208	16	intervention	intervention	NN
cord-344382-vge4ho2v	208	17	for	for	IN
cord-344382-vge4ho2v	208	18	ST	ST	NNP
cord-344382-vge4ho2v	208	19	-	-	HYPH
cord-344382-vge4ho2v	208	20	segment	segment	NN
cord-344382-vge4ho2v	208	21	-	-	HYPH
cord-344382-vge4ho2v	208	22	elevation	elevation	NN
cord-344382-vge4ho2v	208	23	myocardial	myocardial	JJ
cord-344382-vge4ho2v	208	24	infarction	infarction	NN
cord-344382-vge4ho2v	208	25	reduces	reduce	VBZ
cord-344382-vge4ho2v	208	26	myocardial	myocardial	JJ
cord-344382-vge4ho2v	208	27	infarct	infarct	NN
cord-344382-vge4ho2v	208	28	size	size	NN
cord-344382-vge4ho2v	208	29	(	(	-LRB-
cord-344382-vge4ho2v	208	30	the	the	DT
cord-344382-vge4ho2v	208	31	NACIAM	NACIAM	NNP
cord-344382-vge4ho2v	208	32	Trial	Trial	NNP
cord-344382-vge4ho2v	208	33	[	[	-LRB-
cord-344382-vge4ho2v	208	34	N	n	NN
cord-344382-vge4ho2v	208	35	-	-	HYPH
cord-344382-vge4ho2v	208	36	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	208	37	in	in	IN
cord-344382-vge4ho2v	208	38	Acute	acute	JJ
cord-344382-vge4ho2v	208	39	Myocardial	Myocardial	NNP
cord-344382-vge4ho2v	208	40	Infarction	Infarction	NNP
cord-344382-vge4ho2v	208	41	]	]	-RRB-
cord-344382-vge4ho2v	208	42	)	)	-RRB-
cord-344382-vge4ho2v	209	1	War	war	NN
cord-344382-vge4ho2v	209	2	to	to	IN
cord-344382-vge4ho2v	209	3	the	the	DT
cord-344382-vge4ho2v	209	4	knife	knife	NN
cord-344382-vge4ho2v	209	5	"	"	''
cord-344382-vge4ho2v	209	6	against	against	IN
cord-344382-vge4ho2v	209	7	thromboinflammation	thromboinflammation	NN
cord-344382-vge4ho2v	209	8	to	to	TO
cord-344382-vge4ho2v	209	9	protect	protect	VB
cord-344382-vge4ho2v	209	10	endothelial	endothelial	JJ
cord-344382-vge4ho2v	209	11	function	function	NN
cord-344382-vge4ho2v	209	12	of	of	IN
cord-344382-vge4ho2v	209	13	COVID-19	covid-19	CD
cord-344382-vge4ho2v	209	14	patients	patient	NNS
cord-344382-vge4ho2v	210	1	COVID-19	covid-19	VB
cord-344382-vge4ho2v	210	2	:	:	:
cord-344382-vge4ho2v	210	3	the	the	DT
cord-344382-vge4ho2v	210	4	potential	potential	JJ
cord-344382-vge4ho2v	210	5	role	role	NN
cord-344382-vge4ho2v	210	6	of	of	IN
cord-344382-vge4ho2v	210	7	copper	copper	NN
cord-344382-vge4ho2v	210	8	and	and	CC
cord-344382-vge4ho2v	210	9	N	n	NN
cord-344382-vge4ho2v	210	10	-	-	HYPH
cord-344382-vge4ho2v	210	11	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	210	12	(	(	-LRB-
cord-344382-vge4ho2v	210	13	NAC	NAC	NNP
cord-344382-vge4ho2v	210	14	)	)	-RRB-
cord-344382-vge4ho2v	210	15	in	in	IN
cord-344382-vge4ho2v	210	16	a	a	DT
cord-344382-vge4ho2v	210	17	combination	combination	NN
cord-344382-vge4ho2v	210	18	of	of	IN
cord-344382-vge4ho2v	210	19	candidate	candidate	NN
cord-344382-vge4ho2v	210	20	antiviral	antiviral	JJ
cord-344382-vge4ho2v	210	21	treatments	treatment	NNS
cord-344382-vge4ho2v	210	22	against	against	IN
cord-344382-vge4ho2v	210	23	SARS	SARS	NNP
cord-344382-vge4ho2v	210	24	-	-	HYPH
cord-344382-vge4ho2v	210	25	CoV-2	CoV-2	NNP
cord-344382-vge4ho2v	210	26	Acetylcysteine	Acetylcysteine	NNP
cord-344382-vge4ho2v	210	27	:	:	:
cord-344382-vge4ho2v	210	28	a	a	DT
cord-344382-vge4ho2v	210	29	potential	potential	JJ
cord-344382-vge4ho2v	210	30	therapeutic	therapeutic	JJ
cord-344382-vge4ho2v	210	31	agent	agent	NN
cord-344382-vge4ho2v	210	32	for	for	IN
cord-344382-vge4ho2v	210	33	SARS	SARS	NNP
cord-344382-vge4ho2v	210	34	-	-	HYPH
cord-344382-vge4ho2v	210	35	CoV-2	CoV-2	NNP
cord-344382-vge4ho2v	210	36	Rationale	rationale	NN
cord-344382-vge4ho2v	210	37	for	for	IN
cord-344382-vge4ho2v	210	38	the	the	DT
cord-344382-vge4ho2v	210	39	use	use	NN
cord-344382-vge4ho2v	210	40	of	of	IN
cord-344382-vge4ho2v	210	41	N	n	NN
cord-344382-vge4ho2v	210	42	-	-	HYPH
cord-344382-vge4ho2v	210	43	acetylcysteine	acetylcysteine	NN
cord-344382-vge4ho2v	210	44	in	in	IN
cord-344382-vge4ho2v	210	45	both	both	DT
cord-344382-vge4ho2v	210	46	prevention	prevention	NN
cord-344382-vge4ho2v	210	47	and	and	CC
cord-344382-vge4ho2v	210	48	adjuvant	adjuvant	NN
cord-344382-vge4ho2v	210	49	therapy	therapy	NN
cord-344382-vge4ho2v	210	50	of	of	IN
cord-344382-vge4ho2v	210	51	COVID-19	COVID-19	NNP
cord-344382-vge4ho2v	211	1	The	the	DT
cord-344382-vge4ho2v	211	2	authors	author	NNS
cord-344382-vge4ho2v	211	3	declare	declare	VBP
cord-344382-vge4ho2v	211	4	no	no	DT
cord-344382-vge4ho2v	211	5	conflicts	conflict	NNS
cord-344382-vge4ho2v	211	6	of	of	IN
cord-344382-vge4ho2v	211	7	interest	interest	NN
cord-344382-vge4ho2v	211	8	to	to	TO
cord-344382-vge4ho2v	211	9	disclose	disclose	VB
cord-344382-vge4ho2v	211	10	.	.	.
cord-344382-vge4ho2v	211	11	 	 	_SP