id sid tid token lemma pos cord-334550-xb0alubj 1 1 key key NN cord-334550-xb0alubj 1 2 : : : cord-334550-xb0alubj 1 3 cord-334550-xb0alubj cord-334550-xb0alubj ADD cord-334550-xb0alubj 1 4 authors author NNS cord-334550-xb0alubj 1 5 : : : cord-334550-xb0alubj 1 6 Samaddar Samaddar NNP cord-334550-xb0alubj 1 7 , , , cord-334550-xb0alubj 1 8 Arghadip Arghadip NNP cord-334550-xb0alubj 1 9 ; ; : cord-334550-xb0alubj 1 10 Gadepalli Gadepalli NNP cord-334550-xb0alubj 1 11 , , , cord-334550-xb0alubj 1 12 Ravisekhar Ravisekhar NNP cord-334550-xb0alubj 1 13 ; ; : cord-334550-xb0alubj 1 14 Nag Nag NNP cord-334550-xb0alubj 1 15 , , , cord-334550-xb0alubj 1 16 Vijaya Vijaya NNP cord-334550-xb0alubj 1 17 Lakshmi Lakshmi NNP cord-334550-xb0alubj 1 18 ; ; : cord-334550-xb0alubj 1 19 Misra Misra NNP cord-334550-xb0alubj 1 20 , , , cord-334550-xb0alubj 1 21 Sanjeev Sanjeev NNP cord-334550-xb0alubj 1 22 title title NN cord-334550-xb0alubj 1 23 : : : cord-334550-xb0alubj 1 24 The the DT cord-334550-xb0alubj 1 25 Enigma Enigma NNP cord-334550-xb0alubj 1 26 of of IN cord-334550-xb0alubj 1 27 Low Low NNP cord-334550-xb0alubj 1 28 COVID-19 COVID-19 NNP cord-334550-xb0alubj 1 29 Fatality Fatality NNP cord-334550-xb0alubj 1 30 Rate rate NN cord-334550-xb0alubj 1 31 in in IN cord-334550-xb0alubj 1 32 India India NNP cord-334550-xb0alubj 1 33 date date NN cord-334550-xb0alubj 1 34 : : : cord-334550-xb0alubj 1 35 2020 2020 CD cord-334550-xb0alubj 1 36 - - HYPH cord-334550-xb0alubj 1 37 07 07 CD cord-334550-xb0alubj 1 38 - - HYPH cord-334550-xb0alubj 1 39 28 28 CD cord-334550-xb0alubj 1 40 journal journal NN cord-334550-xb0alubj 1 41 : : : cord-334550-xb0alubj 2 1 Front front JJ cord-334550-xb0alubj 2 2 Genet Genet NNP cord-334550-xb0alubj 2 3 DOI DOI NNP cord-334550-xb0alubj 2 4 : : : cord-334550-xb0alubj 2 5 10.3389/ 10.3389/ CD cord-334550-xb0alubj 3 1 fgene.2020.00854 fgene.2020.00854 NFP cord-334550-xb0alubj 3 2 sha sha NN cord-334550-xb0alubj 3 3 : : : cord-334550-xb0alubj 4 1 79610aff70abf0bbd1f4d54e725574cfec49ea04 79610aff70abf0bbd1f4d54e725574cfec49ea04 CD cord-334550-xb0alubj 4 2 doc_id doc_id CD cord-334550-xb0alubj 4 3 : : : cord-334550-xb0alubj 4 4 334550 334550 CD cord-334550-xb0alubj 4 5 cord_uid cord_uid NNS cord-334550-xb0alubj 4 6 : : : cord-334550-xb0alubj 5 1 xb0alubj xb0alubj NNP cord-334550-xb0alubj 6 1 Coronavirus Coronavirus NNP cord-334550-xb0alubj 6 2 disease disease NN cord-334550-xb0alubj 6 3 2019 2019 CD cord-334550-xb0alubj 6 4 ( ( -LRB- cord-334550-xb0alubj 6 5 COVID-19 COVID-19 NNP cord-334550-xb0alubj 6 6 ) ) -RRB- cord-334550-xb0alubj 6 7 , , , cord-334550-xb0alubj 6 8 an an DT cord-334550-xb0alubj 6 9 acute acute JJ cord-334550-xb0alubj 6 10 onset onset NN cord-334550-xb0alubj 6 11 pneumonia pneumonia NN cord-334550-xb0alubj 6 12 caused cause VBN cord-334550-xb0alubj 6 13 by by IN cord-334550-xb0alubj 6 14 a a DT cord-334550-xb0alubj 6 15 novel novel NN cord-334550-xb0alubj 6 16 Betacoronavirus Betacoronavirus NNP cord-334550-xb0alubj 6 17 Severe Severe NNP cord-334550-xb0alubj 6 18 Acute acute JJ cord-334550-xb0alubj 6 19 Respiratory Respiratory NNP cord-334550-xb0alubj 6 20 Syndrome Syndrome NNP cord-334550-xb0alubj 6 21 Coronavirus Coronavirus NNP cord-334550-xb0alubj 6 22 2 2 CD cord-334550-xb0alubj 7 1 ( ( -LRB- cord-334550-xb0alubj 7 2 SARS SARS NNP cord-334550-xb0alubj 7 3 - - HYPH cord-334550-xb0alubj 7 4 CoV-2 CoV-2 NNP cord-334550-xb0alubj 7 5 ) ) -RRB- cord-334550-xb0alubj 7 6 has have VBZ cord-334550-xb0alubj 7 7 rapidly rapidly RB cord-334550-xb0alubj 7 8 evolved evolve VBN cord-334550-xb0alubj 7 9 into into IN cord-334550-xb0alubj 7 10 a a DT cord-334550-xb0alubj 7 11 pandemic pandemic NN cord-334550-xb0alubj 7 12 . . . cord-334550-xb0alubj 8 1 Though though IN cord-334550-xb0alubj 8 2 its -PRON- PRP$ cord-334550-xb0alubj 8 3 origin origin NN cord-334550-xb0alubj 8 4 has have VBZ cord-334550-xb0alubj 8 5 been be VBN cord-334550-xb0alubj 8 6 linked link VBN cord-334550-xb0alubj 8 7 to to IN cord-334550-xb0alubj 8 8 the the DT cord-334550-xb0alubj 8 9 Wuhan Wuhan NNP cord-334550-xb0alubj 8 10 City City NNP cord-334550-xb0alubj 8 11 of of IN cord-334550-xb0alubj 8 12 China China NNP cord-334550-xb0alubj 8 13 ’s ’s POS cord-334550-xb0alubj 8 14 Hubei Hubei NNP cord-334550-xb0alubj 8 15 Province Province NNP cord-334550-xb0alubj 8 16 in in IN cord-334550-xb0alubj 8 17 December December NNP cord-334550-xb0alubj 8 18 2019 2019 CD cord-334550-xb0alubj 8 19 , , , cord-334550-xb0alubj 8 20 recent recent JJ cord-334550-xb0alubj 8 21 reports report NNS cord-334550-xb0alubj 8 22 claim claim VBP cord-334550-xb0alubj 8 23 that that IN cord-334550-xb0alubj 8 24 the the DT cord-334550-xb0alubj 8 25 original original JJ cord-334550-xb0alubj 8 26 animal animal NN cord-334550-xb0alubj 8 27 - - HYPH cord-334550-xb0alubj 8 28 to to IN cord-334550-xb0alubj 8 29 - - HYPH cord-334550-xb0alubj 8 30 human human JJ cord-334550-xb0alubj 8 31 transmission transmission NN cord-334550-xb0alubj 8 32 of of IN cord-334550-xb0alubj 8 33 the the DT cord-334550-xb0alubj 8 34 virus virus NN cord-334550-xb0alubj 8 35 probably probably RB cord-334550-xb0alubj 8 36 happened happen VBD cord-334550-xb0alubj 8 37 sometime sometime RB cord-334550-xb0alubj 8 38 between between IN cord-334550-xb0alubj 8 39 September September NNP cord-334550-xb0alubj 8 40 and and CC cord-334550-xb0alubj 8 41 October October NNP cord-334550-xb0alubj 8 42 2019 2019 CD cord-334550-xb0alubj 8 43 in in IN cord-334550-xb0alubj 8 44 Guangdong Guangdong NNP cord-334550-xb0alubj 8 45 Province Province NNP cord-334550-xb0alubj 8 46 , , , cord-334550-xb0alubj 8 47 rather rather RB cord-334550-xb0alubj 8 48 than than IN cord-334550-xb0alubj 8 49 Hubei Hubei NNP cord-334550-xb0alubj 8 50 . . . cord-334550-xb0alubj 9 1 As as IN cord-334550-xb0alubj 9 2 of of IN cord-334550-xb0alubj 9 3 July July NNP cord-334550-xb0alubj 9 4 3 3 CD cord-334550-xb0alubj 9 5 , , , cord-334550-xb0alubj 9 6 2020 2020 CD cord-334550-xb0alubj 9 7 , , , cord-334550-xb0alubj 9 8 India India NNP cord-334550-xb0alubj 9 9 has have VBZ cord-334550-xb0alubj 9 10 reported report VBN cord-334550-xb0alubj 9 11 a a DT cord-334550-xb0alubj 9 12 case case NN cord-334550-xb0alubj 9 13 positivity positivity NN cord-334550-xb0alubj 9 14 rate rate NN cord-334550-xb0alubj 9 15 of of IN cord-334550-xb0alubj 9 16 6.5 6.5 CD cord-334550-xb0alubj 9 17 % % NN cord-334550-xb0alubj 9 18 and and CC cord-334550-xb0alubj 9 19 a a DT cord-334550-xb0alubj 9 20 fatality fatality NN cord-334550-xb0alubj 9 21 rate rate NN cord-334550-xb0alubj 9 22 of of IN cord-334550-xb0alubj 9 23 2.8 2.8 CD cord-334550-xb0alubj 9 24 % % NN cord-334550-xb0alubj 9 25 , , , cord-334550-xb0alubj 9 26 which which WDT cord-334550-xb0alubj 9 27 are be VBP cord-334550-xb0alubj 9 28 among among IN cord-334550-xb0alubj 9 29 the the DT cord-334550-xb0alubj 9 30 lowest low JJS cord-334550-xb0alubj 9 31 in in IN cord-334550-xb0alubj 9 32 the the DT cord-334550-xb0alubj 9 33 world world NN cord-334550-xb0alubj 9 34 . . . cord-334550-xb0alubj 10 1 Also also RB cord-334550-xb0alubj 10 2 , , , cord-334550-xb0alubj 10 3 the the DT cord-334550-xb0alubj 10 4 severity severity NN cord-334550-xb0alubj 10 5 of of IN cord-334550-xb0alubj 10 6 the the DT cord-334550-xb0alubj 10 7 disease disease NN cord-334550-xb0alubj 10 8 is be VBZ cord-334550-xb0alubj 10 9 much much RB cord-334550-xb0alubj 10 10 less less JJR cord-334550-xb0alubj 10 11 among among IN cord-334550-xb0alubj 10 12 Indians Indians NNPS cord-334550-xb0alubj 10 13 as as IN cord-334550-xb0alubj 10 14 evidenced evidence VBN cord-334550-xb0alubj 10 15 by by IN cord-334550-xb0alubj 10 16 the the DT cord-334550-xb0alubj 10 17 low low JJ cord-334550-xb0alubj 10 18 rate rate NN cord-334550-xb0alubj 10 19 of of IN cord-334550-xb0alubj 10 20 ICU ICU NNP cord-334550-xb0alubj 10 21 admission admission NN cord-334550-xb0alubj 10 22 ( ( -LRB- cord-334550-xb0alubj 10 23 15.3 15.3 CD cord-334550-xb0alubj 10 24 % % NN cord-334550-xb0alubj 10 25 ) ) -RRB- cord-334550-xb0alubj 10 26 and and CC cord-334550-xb0alubj 10 27 the the DT cord-334550-xb0alubj 10 28 need need NN cord-334550-xb0alubj 10 29 for for IN cord-334550-xb0alubj 10 30 mechanical mechanical JJ cord-334550-xb0alubj 10 31 ventilation ventilation NN cord-334550-xb0alubj 10 32 ( ( -LRB- cord-334550-xb0alubj 10 33 4.16 4.16 CD cord-334550-xb0alubj 10 34 % % NN cord-334550-xb0alubj 10 35 ) ) -RRB- cord-334550-xb0alubj 10 36 . . . cord-334550-xb0alubj 11 1 As as IN cord-334550-xb0alubj 11 2 per per IN cord-334550-xb0alubj 11 3 the the DT cord-334550-xb0alubj 11 4 World World NNP cord-334550-xb0alubj 11 5 Health Health NNP cord-334550-xb0alubj 11 6 Organization Organization NNP cord-334550-xb0alubj 11 7 ( ( -LRB- cord-334550-xb0alubj 11 8 WHO who WP cord-334550-xb0alubj 11 9 ) ) -RRB- cord-334550-xb0alubj 11 10 situation situation NN cord-334550-xb0alubj 11 11 report report NN cord-334550-xb0alubj 11 12 165 165 CD cord-334550-xb0alubj 11 13 on on IN cord-334550-xb0alubj 11 14 July July NNP cord-334550-xb0alubj 11 15 3 3 CD cord-334550-xb0alubj 11 16 , , , cord-334550-xb0alubj 11 17 2020 2020 CD cord-334550-xb0alubj 11 18 , , , cord-334550-xb0alubj 11 19 India India NNP cord-334550-xb0alubj 11 20 has have VBZ cord-334550-xb0alubj 11 21 one one CD cord-334550-xb0alubj 11 22 of of IN cord-334550-xb0alubj 11 23 the the DT cord-334550-xb0alubj 11 24 lowest low JJS cord-334550-xb0alubj 11 25 deaths death NNS cord-334550-xb0alubj 11 26 per per IN cord-334550-xb0alubj 11 27 100,000 100,000 CD cord-334550-xb0alubj 11 28 population population NN cord-334550-xb0alubj 11 29 ( ( -LRB- cord-334550-xb0alubj 11 30 1.32 1.32 CD cord-334550-xb0alubj 11 31 deaths death NNS cord-334550-xb0alubj 11 32 against against IN cord-334550-xb0alubj 11 33 a a DT cord-334550-xb0alubj 11 34 global global JJ cord-334550-xb0alubj 11 35 average average NN cord-334550-xb0alubj 11 36 of of IN cord-334550-xb0alubj 11 37 6.04 6.04 CD cord-334550-xb0alubj 11 38 ) ) -RRB- cord-334550-xb0alubj 11 39 . . . cord-334550-xb0alubj 12 1 Several several JJ cord-334550-xb0alubj 12 2 factors factor NNS cord-334550-xb0alubj 12 3 related relate VBN cord-334550-xb0alubj 12 4 to to IN cord-334550-xb0alubj 12 5 the the DT cord-334550-xb0alubj 12 6 pathogen pathogen NN cord-334550-xb0alubj 12 7 , , , cord-334550-xb0alubj 12 8 host host NN cord-334550-xb0alubj 12 9 and and CC cord-334550-xb0alubj 12 10 environment environment NN cord-334550-xb0alubj 12 11 might may MD cord-334550-xb0alubj 12 12 have have VB cord-334550-xb0alubj 12 13 some some DT cord-334550-xb0alubj 12 14 role role NN cord-334550-xb0alubj 12 15 in in IN cord-334550-xb0alubj 12 16 reducing reduce VBG cord-334550-xb0alubj 12 17 the the DT cord-334550-xb0alubj 12 18 susceptibility susceptibility NN cord-334550-xb0alubj 12 19 of of IN cord-334550-xb0alubj 12 20 Indians Indians NNPS cord-334550-xb0alubj 12 21 to to TO cord-334550-xb0alubj 12 22 COVID-19 covid-19 VB cord-334550-xb0alubj 12 23 . . . cord-334550-xb0alubj 13 1 These these DT cord-334550-xb0alubj 13 2 include include VBP cord-334550-xb0alubj 13 3 some some DT cord-334550-xb0alubj 13 4 ongoing ongoing JJ cord-334550-xb0alubj 13 5 mutations mutation NNS cord-334550-xb0alubj 13 6 that that WDT cord-334550-xb0alubj 13 7 can can MD cord-334550-xb0alubj 13 8 alter alter VB cord-334550-xb0alubj 13 9 the the DT cord-334550-xb0alubj 13 10 virulence virulence NN cord-334550-xb0alubj 13 11 of of IN cord-334550-xb0alubj 13 12 the the DT cord-334550-xb0alubj 13 13 circulating circulate VBG cord-334550-xb0alubj 13 14 SARS SARS NNP cord-334550-xb0alubj 13 15 - - HYPH cord-334550-xb0alubj 13 16 CoV-2 CoV-2 NNP cord-334550-xb0alubj 13 17 strains strain NNS cord-334550-xb0alubj 13 18 , , , cord-334550-xb0alubj 13 19 host host NN cord-334550-xb0alubj 13 20 factors factor NNS cord-334550-xb0alubj 13 21 like like IN cord-334550-xb0alubj 13 22 innate innate JJ cord-334550-xb0alubj 13 23 immunity immunity NN cord-334550-xb0alubj 13 24 , , , cord-334550-xb0alubj 13 25 genetic genetic JJ cord-334550-xb0alubj 13 26 diversity diversity NN cord-334550-xb0alubj 13 27 in in IN cord-334550-xb0alubj 13 28 immune immune JJ cord-334550-xb0alubj 13 29 responses response NNS cord-334550-xb0alubj 13 30 , , , cord-334550-xb0alubj 13 31 epigenetic epigenetic JJ cord-334550-xb0alubj 13 32 factors factor NNS cord-334550-xb0alubj 13 33 , , , cord-334550-xb0alubj 13 34 genetic genetic JJ cord-334550-xb0alubj 13 35 polymorphisms polymorphism NNS cord-334550-xb0alubj 13 36 of of IN cord-334550-xb0alubj 13 37 ACE2 ACE2 NNP cord-334550-xb0alubj 13 38 receptors receptor NNS cord-334550-xb0alubj 13 39 , , , cord-334550-xb0alubj 13 40 micro micro NNP cord-334550-xb0alubj 13 41 RNAs RNAs NNPS cord-334550-xb0alubj 13 42 and and CC cord-334550-xb0alubj 13 43 universal universal JJ cord-334550-xb0alubj 13 44 BCG BCG NNP cord-334550-xb0alubj 13 45 vaccination vaccination NN cord-334550-xb0alubj 13 46 , , , cord-334550-xb0alubj 13 47 and and CC cord-334550-xb0alubj 13 48 environmental environmental JJ cord-334550-xb0alubj 13 49 factors factor NNS cord-334550-xb0alubj 13 50 like like IN cord-334550-xb0alubj 13 51 high high JJ cord-334550-xb0alubj 13 52 temperature temperature NN cord-334550-xb0alubj 13 53 and and CC cord-334550-xb0alubj 13 54 humidity humidity NN cord-334550-xb0alubj 13 55 which which WDT cord-334550-xb0alubj 13 56 may may MD cord-334550-xb0alubj 13 57 alter alter VB cord-334550-xb0alubj 13 58 the the DT cord-334550-xb0alubj 13 59 viability viability NN cord-334550-xb0alubj 13 60 and and CC cord-334550-xb0alubj 13 61 transmissibility transmissibility NN cord-334550-xb0alubj 13 62 of of IN cord-334550-xb0alubj 13 63 the the DT cord-334550-xb0alubj 13 64 strain strain NN cord-334550-xb0alubj 13 65 . . . cord-334550-xb0alubj 14 1 This this DT cord-334550-xb0alubj 14 2 perspective perspective NN cord-334550-xb0alubj 14 3 -highlights -highlight VBZ cord-334550-xb0alubj 14 4 the the DT cord-334550-xb0alubj 14 5 potential potential JJ cord-334550-xb0alubj 14 6 factors factor NNS cord-334550-xb0alubj 14 7 that that WDT cord-334550-xb0alubj 14 8 might may MD cord-334550-xb0alubj 14 9 be be VB cord-334550-xb0alubj 14 10 responsible responsible JJ cord-334550-xb0alubj 14 11 for for IN cord-334550-xb0alubj 14 12 the the DT cord-334550-xb0alubj 14 13 observed observed JJ cord-334550-xb0alubj 14 14 low low JJ cord-334550-xb0alubj 14 15 COVID-19 covid-19 JJ cord-334550-xb0alubj 14 16 fatality fatality NN cord-334550-xb0alubj 14 17 rate rate NN cord-334550-xb0alubj 14 18 in in IN cord-334550-xb0alubj 14 19 Indian indian JJ cord-334550-xb0alubj 14 20 population population NN cord-334550-xb0alubj 14 21 . . . cord-334550-xb0alubj 15 1 It -PRON- PRP cord-334550-xb0alubj 15 2 puts put VBZ cord-334550-xb0alubj 15 3 forward forward RB cord-334550-xb0alubj 15 4 several several JJ cord-334550-xb0alubj 15 5 hypotheses hypothesis NNS cord-334550-xb0alubj 15 6 which which WDT cord-334550-xb0alubj 15 7 can can MD cord-334550-xb0alubj 15 8 be be VB cord-334550-xb0alubj 15 9 a a DT cord-334550-xb0alubj 15 10 ground ground NN cord-334550-xb0alubj 15 11 for for IN cord-334550-xb0alubj 15 12 future future JJ cord-334550-xb0alubj 15 13 studies study NNS cord-334550-xb0alubj 15 14 determining determine VBG cord-334550-xb0alubj 15 15 individual individual JJ cord-334550-xb0alubj 15 16 and and CC cord-334550-xb0alubj 15 17 population population NN cord-334550-xb0alubj 15 18 susceptibility susceptibility NN cord-334550-xb0alubj 15 19 to to TO cord-334550-xb0alubj 15 20 COVID-19 covid-19 VB cord-334550-xb0alubj 15 21 and and CC cord-334550-xb0alubj 15 22 thus thus RB cord-334550-xb0alubj 15 23 , , , cord-334550-xb0alubj 15 24 may may MD cord-334550-xb0alubj 15 25 offer offer VB cord-334550-xb0alubj 15 26 a a DT cord-334550-xb0alubj 15 27 new new JJ cord-334550-xb0alubj 15 28 dimension dimension NN cord-334550-xb0alubj 15 29 to to IN cord-334550-xb0alubj 15 30 our -PRON- PRP$ cord-334550-xb0alubj 15 31 current current JJ cord-334550-xb0alubj 15 32 understanding understanding NN cord-334550-xb0alubj 15 33 of of IN cord-334550-xb0alubj 15 34 the the DT cord-334550-xb0alubj 15 35 disease disease NN cord-334550-xb0alubj 15 36 . . . cord-334550-xb0alubj 16 1 In in IN cord-334550-xb0alubj 16 2 December December NNP cord-334550-xb0alubj 16 3 2019 2019 CD cord-334550-xb0alubj 16 4 , , , cord-334550-xb0alubj 16 5 an an DT cord-334550-xb0alubj 16 6 outbreak outbreak NN cord-334550-xb0alubj 16 7 of of IN cord-334550-xb0alubj 16 8 fatal fatal JJ cord-334550-xb0alubj 16 9 pneumonia pneumonia NN cord-334550-xb0alubj 16 10 , , , cord-334550-xb0alubj 16 11 the the DT cord-334550-xb0alubj 16 12 Coronavirus Coronavirus NNP cord-334550-xb0alubj 16 13 Disease Disease NNP cord-334550-xb0alubj 16 14 2019 2019 CD cord-334550-xb0alubj 16 15 , , , cord-334550-xb0alubj 16 16 caused cause VBN cord-334550-xb0alubj 16 17 by by IN cord-334550-xb0alubj 16 18 a a DT cord-334550-xb0alubj 16 19 novel novel NN cord-334550-xb0alubj 16 20 Betacoronavirus Betacoronavirus NNP cord-334550-xb0alubj 16 21 , , , cord-334550-xb0alubj 16 22 Severe severe JJ cord-334550-xb0alubj 16 23 Acute acute JJ cord-334550-xb0alubj 16 24 Respiratory Respiratory NNP cord-334550-xb0alubj 16 25 Syndrome Syndrome NNP cord-334550-xb0alubj 16 26 Coronavirus Coronavirus NNP cord-334550-xb0alubj 16 27 2 2 CD cord-334550-xb0alubj 16 28 ( ( -LRB- cord-334550-xb0alubj 16 29 SARS SARS NNP cord-334550-xb0alubj 16 30 - - HYPH cord-334550-xb0alubj 16 31 CoV-2 CoV-2 NNP cord-334550-xb0alubj 16 32 ) ) -RRB- cord-334550-xb0alubj 16 33 was be VBD cord-334550-xb0alubj 16 34 reported report VBN cord-334550-xb0alubj 16 35 from from IN cord-334550-xb0alubj 16 36 the the DT cord-334550-xb0alubj 16 37 Wuhan Wuhan NNP cord-334550-xb0alubj 16 38 City City NNP cord-334550-xb0alubj 16 39 of of IN cord-334550-xb0alubj 16 40 China China NNP cord-334550-xb0alubj 16 41 's 's POS cord-334550-xb0alubj 16 42 Hubei Hubei NNP cord-334550-xb0alubj 16 43 Province Province NNP cord-334550-xb0alubj 16 44 . . . cord-334550-xb0alubj 17 1 The the DT cord-334550-xb0alubj 17 2 outbreak outbreak NN cord-334550-xb0alubj 17 3 was be VBD cord-334550-xb0alubj 17 4 declared declare VBN cord-334550-xb0alubj 17 5 as as IN cord-334550-xb0alubj 17 6 a a DT cord-334550-xb0alubj 17 7 Public Public NNP cord-334550-xb0alubj 17 8 Health Health NNP cord-334550-xb0alubj 17 9 Emergency Emergency NNP cord-334550-xb0alubj 17 10 of of IN cord-334550-xb0alubj 17 11 International International NNP cord-334550-xb0alubj 17 12 Concern Concern NNP cord-334550-xb0alubj 17 13 by by IN cord-334550-xb0alubj 17 14 the the DT cord-334550-xb0alubj 17 15 World World NNP cord-334550-xb0alubj 17 16 Health Health NNP cord-334550-xb0alubj 17 17 Organization Organization NNP cord-334550-xb0alubj 17 18 ( ( -LRB- cord-334550-xb0alubj 17 19 WHO who WP cord-334550-xb0alubj 17 20 ) ) -RRB- cord-334550-xb0alubj 17 21 on on IN cord-334550-xb0alubj 17 22 January January NNP cord-334550-xb0alubj 17 23 30 30 CD cord-334550-xb0alubj 17 24 , , , cord-334550-xb0alubj 17 25 2020 2020 CD cord-334550-xb0alubj 17 26 and and CC cord-334550-xb0alubj 17 27 a a DT cord-334550-xb0alubj 17 28 global global JJ cord-334550-xb0alubj 17 29 pandemic pandemic NN cord-334550-xb0alubj 17 30 on on IN cord-334550-xb0alubj 17 31 March March NNP cord-334550-xb0alubj 17 32 11 11 CD cord-334550-xb0alubj 17 33 , , , cord-334550-xb0alubj 17 34 2020 2020 CD cord-334550-xb0alubj 17 35 . . . cord-334550-xb0alubj 18 1 1,2 1,2 LS cord-334550-xb0alubj 19 1 Though though IN cord-334550-xb0alubj 19 2 its -PRON- PRP$ cord-334550-xb0alubj 19 3 origin origin NN cord-334550-xb0alubj 19 4 has have VBZ cord-334550-xb0alubj 19 5 been be VBN cord-334550-xb0alubj 19 6 linked link VBN cord-334550-xb0alubj 19 7 to to IN cord-334550-xb0alubj 19 8 Hubei Hubei NNP cord-334550-xb0alubj 19 9 Province Province NNP cord-334550-xb0alubj 19 10 , , , cord-334550-xb0alubj 19 11 recent recent JJ cord-334550-xb0alubj 19 12 phylogenetic phylogenetic JJ cord-334550-xb0alubj 19 13 analysis analysis NN cord-334550-xb0alubj 19 14 claims claim VBZ cord-334550-xb0alubj 19 15 that that IN cord-334550-xb0alubj 19 16 the the DT cord-334550-xb0alubj 19 17 original original JJ cord-334550-xb0alubj 19 18 animal animal NN cord-334550-xb0alubj 19 19 - - HYPH cord-334550-xb0alubj 19 20 tohuman tohuman NN cord-334550-xb0alubj 19 21 transmission transmission NN cord-334550-xb0alubj 19 22 of of IN cord-334550-xb0alubj 19 23 the the DT cord-334550-xb0alubj 19 24 virus virus NN cord-334550-xb0alubj 19 25 probably probably RB cord-334550-xb0alubj 19 26 happened happen VBD cord-334550-xb0alubj 19 27 some some DT cord-334550-xb0alubj 19 28 3 3 CD cord-334550-xb0alubj 19 29 to to TO cord-334550-xb0alubj 19 30 4 4 CD cord-334550-xb0alubj 19 31 months month NNS cord-334550-xb0alubj 19 32 before before IN cord-334550-xb0alubj 19 33 December December NNP cord-334550-xb0alubj 19 34 2019 2019 CD cord-334550-xb0alubj 19 35 in in IN cord-334550-xb0alubj 19 36 Guangdong Guangdong NNP cord-334550-xb0alubj 19 37 Province Province NNP cord-334550-xb0alubj 19 38 , , , cord-334550-xb0alubj 19 39 rather rather RB cord-334550-xb0alubj 19 40 than than IN cord-334550-xb0alubj 19 41 Hubei Hubei NNP cord-334550-xb0alubj 20 1 ( ( -LRB- cord-334550-xb0alubj 20 2 Forster Forster NNP cord-334550-xb0alubj 20 3 et et NNP cord-334550-xb0alubj 20 4 al al NNP cord-334550-xb0alubj 20 5 . . NNP cord-334550-xb0alubj 20 6 , , , cord-334550-xb0alubj 20 7 2020 2020 CD cord-334550-xb0alubj 20 8 ) ) -RRB- cord-334550-xb0alubj 20 9 . . . cord-334550-xb0alubj 21 1 As as IN cord-334550-xb0alubj 21 2 of of IN cord-334550-xb0alubj 21 3 July July NNP cord-334550-xb0alubj 21 4 3 3 CD cord-334550-xb0alubj 21 5 , , , cord-334550-xb0alubj 21 6 2020 2020 CD cord-334550-xb0alubj 21 7 , , , cord-334550-xb0alubj 21 8 the the DT cord-334550-xb0alubj 21 9 disease disease NN cord-334550-xb0alubj 21 10 has have VBZ cord-334550-xb0alubj 21 11 affected affect VBN cord-334550-xb0alubj 21 12 more more JJR cord-334550-xb0alubj 21 13 than than IN cord-334550-xb0alubj 21 14 10.7 10.7 CD cord-334550-xb0alubj 21 15 million million CD cord-334550-xb0alubj 21 16 people people NNS cord-334550-xb0alubj 21 17 across across IN cord-334550-xb0alubj 21 18 216 216 CD cord-334550-xb0alubj 21 19 countries country NNS cord-334550-xb0alubj 21 20 and and CC cord-334550-xb0alubj 21 21 territories territory NNS cord-334550-xb0alubj 21 22 with with IN cord-334550-xb0alubj 21 23 517,877 517,877 CD cord-334550-xb0alubj 21 24 deaths death NNS cord-334550-xb0alubj 21 25 . . . cord-334550-xb0alubj 22 1 3 3 LS cord-334550-xb0alubj 23 1 A a DT cord-334550-xb0alubj 23 2 difference difference NN cord-334550-xb0alubj 23 3 in in IN cord-334550-xb0alubj 23 4 the the DT cord-334550-xb0alubj 23 5 case case NN cord-334550-xb0alubj 23 6 fatality fatality NN cord-334550-xb0alubj 23 7 rates rate NNS cord-334550-xb0alubj 23 8 ( ( -LRB- cord-334550-xb0alubj 23 9 CFR CFR NNP cord-334550-xb0alubj 23 10 ) ) -RRB- cord-334550-xb0alubj 23 11 was be VBD cord-334550-xb0alubj 23 12 observed observe VBN cord-334550-xb0alubj 23 13 across across IN cord-334550-xb0alubj 23 14 countries country NNS cord-334550-xb0alubj 23 15 , , , cord-334550-xb0alubj 23 16 possibly possibly RB cord-334550-xb0alubj 23 17 due due JJ cord-334550-xb0alubj 23 18 to to IN cord-334550-xb0alubj 23 19 demographic demographic JJ cord-334550-xb0alubj 23 20 variations variation NNS cord-334550-xb0alubj 23 21 , , , cord-334550-xb0alubj 23 22 differences difference NNS cord-334550-xb0alubj 23 23 in in IN cord-334550-xb0alubj 23 24 the the DT cord-334550-xb0alubj 23 25 virus virus NN cord-334550-xb0alubj 23 26 strains strain VBZ cord-334550-xb0alubj 23 27 in in IN cord-334550-xb0alubj 23 28 circulation circulation NN cord-334550-xb0alubj 23 29 and and CC cord-334550-xb0alubj 23 30 the the DT cord-334550-xb0alubj 23 31 nature nature NN cord-334550-xb0alubj 23 32 of of IN cord-334550-xb0alubj 23 33 containment containment NN cord-334550-xb0alubj 23 34 measures measure NNS cord-334550-xb0alubj 23 35 implemented implement VBN cord-334550-xb0alubj 23 36 . . . cord-334550-xb0alubj 24 1 The the DT cord-334550-xb0alubj 24 2 fatality fatality NN cord-334550-xb0alubj 24 3 rates rate NNS cord-334550-xb0alubj 24 4 in in IN cord-334550-xb0alubj 24 5 the the DT cord-334550-xb0alubj 24 6 United United NNP cord-334550-xb0alubj 24 7 States States NNP cord-334550-xb0alubj 24 8 , , , cord-334550-xb0alubj 24 9 United United NNP cord-334550-xb0alubj 24 10 Kingdom Kingdom NNP cord-334550-xb0alubj 24 11 , , , cord-334550-xb0alubj 24 12 Italy Italy NNP cord-334550-xb0alubj 24 13 , , , cord-334550-xb0alubj 24 14 France France NNP cord-334550-xb0alubj 24 15 , , , cord-334550-xb0alubj 24 16 and and CC cord-334550-xb0alubj 24 17 Spain Spain NNP cord-334550-xb0alubj 24 18 have have VBP cord-334550-xb0alubj 24 19 surpassed surpass VBN cord-334550-xb0alubj 24 20 that that DT cord-334550-xb0alubj 24 21 of of IN cord-334550-xb0alubj 24 22 China China NNP cord-334550-xb0alubj 24 23 by by IN cord-334550-xb0alubj 24 24 manifolds manifold NNS cord-334550-xb0alubj 24 25 . . . cord-334550-xb0alubj 25 1 India India NNP cord-334550-xb0alubj 25 2 , , , cord-334550-xb0alubj 25 3 the the DT cord-334550-xb0alubj 25 4 second second JJ cord-334550-xb0alubj 25 5 most most RBS cord-334550-xb0alubj 25 6 populous populous JJ cord-334550-xb0alubj 25 7 country country NN cord-334550-xb0alubj 25 8 in in IN cord-334550-xb0alubj 25 9 the the DT cord-334550-xb0alubj 25 10 world world NN cord-334550-xb0alubj 25 11 , , , cord-334550-xb0alubj 25 12 with with IN cord-334550-xb0alubj 25 13 a a DT cord-334550-xb0alubj 25 14 population population NN cord-334550-xb0alubj 25 15 of of IN cord-334550-xb0alubj 25 16 1.3 1.3 CD cord-334550-xb0alubj 25 17 billion billion CD cord-334550-xb0alubj 25 18 people people NNS cord-334550-xb0alubj 25 19 , , , cord-334550-xb0alubj 25 20 had have VBD cord-334550-xb0alubj 25 21 documented document VBN cord-334550-xb0alubj 25 22 the the DT cord-334550-xb0alubj 25 23 first first JJ cord-334550-xb0alubj 25 24 case case NN cord-334550-xb0alubj 25 25 of of IN cord-334550-xb0alubj 25 26 COVID-19 COVID-19 NNP cord-334550-xb0alubj 25 27 on on IN cord-334550-xb0alubj 25 28 January January NNP cord-334550-xb0alubj 25 29 30 30 CD cord-334550-xb0alubj 25 30 , , , cord-334550-xb0alubj 25 31 2020 2020 CD cord-334550-xb0alubj 25 32 , , , cord-334550-xb0alubj 25 33 the the DT cord-334550-xb0alubj 25 34 same same JJ cord-334550-xb0alubj 25 35 day day NN cord-334550-xb0alubj 25 36 as as IN cord-334550-xb0alubj 25 37 Italy Italy NNP cord-334550-xb0alubj 26 1 ( ( -LRB- cord-334550-xb0alubj 26 2 Kaushik Kaushik NNP cord-334550-xb0alubj 26 3 et et NNP cord-334550-xb0alubj 26 4 al al NNP cord-334550-xb0alubj 26 5 . . NNP cord-334550-xb0alubj 26 6 , , , cord-334550-xb0alubj 26 7 2020 2020 CD cord-334550-xb0alubj 26 8 ) ) -RRB- cord-334550-xb0alubj 26 9 . . . cord-334550-xb0alubj 27 1 As as IN cord-334550-xb0alubj 27 2 of of IN cord-334550-xb0alubj 27 3 July July NNP cord-334550-xb0alubj 27 4 3 3 CD cord-334550-xb0alubj 27 5 , , , cord-334550-xb0alubj 27 6 2020 2020 CD cord-334550-xb0alubj 27 7 , , , cord-334550-xb0alubj 27 8 India India NNP cord-334550-xb0alubj 27 9 has have VBZ cord-334550-xb0alubj 27 10 reported report VBN cord-334550-xb0alubj 27 11 a a DT cord-334550-xb0alubj 27 12 total total NN cord-334550-xb0alubj 27 13 of of IN cord-334550-xb0alubj 27 14 625,544 625,544 CD cord-334550-xb0alubj 27 15 cases case NNS cord-334550-xb0alubj 27 16 and and CC cord-334550-xb0alubj 27 17 18,213 18,213 CD cord-334550-xb0alubj 27 18 deaths death NNS cord-334550-xb0alubj 27 19 which which WDT cord-334550-xb0alubj 27 20 reflects reflect VBZ cord-334550-xb0alubj 27 21 a a DT cord-334550-xb0alubj 27 22 milder mild JJR cord-334550-xb0alubj 27 23 trajectory trajectory NN cord-334550-xb0alubj 27 24 with with IN cord-334550-xb0alubj 27 25 lower low JJR cord-334550-xb0alubj 27 26 case case NN cord-334550-xb0alubj 27 27 positivity positivity NN cord-334550-xb0alubj 27 28 ( ( -LRB- cord-334550-xb0alubj 27 29 6.5 6.5 CD cord-334550-xb0alubj 27 30 % % NN cord-334550-xb0alubj 27 31 ) ) -RRB- cord-334550-xb0alubj 27 32 and and CC cord-334550-xb0alubj 27 33 fatality fatality NN cord-334550-xb0alubj 27 34 ( ( -LRB- cord-334550-xb0alubj 27 35 2.8 2.8 CD cord-334550-xb0alubj 27 36 % % NN cord-334550-xb0alubj 27 37 ) ) -RRB- cord-334550-xb0alubj 27 38 rates rate NNS cord-334550-xb0alubj 27 39 compared compare VBN cord-334550-xb0alubj 27 40 to to IN cord-334550-xb0alubj 27 41 the the DT cord-334550-xb0alubj 27 42 global global JJ cord-334550-xb0alubj 27 43 figures figure NNS cord-334550-xb0alubj 27 44 . . . cord-334550-xb0alubj 28 1 3 3 LS cord-334550-xb0alubj 29 1 The the DT cord-334550-xb0alubj 29 2 traditional traditional JJ cord-334550-xb0alubj 29 3 model model NN cord-334550-xb0alubj 29 4 for for IN cord-334550-xb0alubj 29 5 any any DT cord-334550-xb0alubj 29 6 infectious infectious JJ cord-334550-xb0alubj 29 7 disease disease NN cord-334550-xb0alubj 29 8 consists consist VBZ cord-334550-xb0alubj 29 9 of of IN cord-334550-xb0alubj 29 10 a a DT cord-334550-xb0alubj 29 11 triad triad NN cord-334550-xb0alubj 29 12 of of IN cord-334550-xb0alubj 29 13 the the DT cord-334550-xb0alubj 29 14 causative causative JJ cord-334550-xb0alubj 29 15 agent agent NN cord-334550-xb0alubj 29 16 , , , cord-334550-xb0alubj 29 17 the the DT cord-334550-xb0alubj 29 18 host host NN cord-334550-xb0alubj 29 19 , , , cord-334550-xb0alubj 29 20 and and CC cord-334550-xb0alubj 29 21 an an DT cord-334550-xb0alubj 29 22 environment environment NN cord-334550-xb0alubj 29 23 in in IN cord-334550-xb0alubj 29 24 which which WDT cord-334550-xb0alubj 29 25 the the DT cord-334550-xb0alubj 29 26 agent agent NN cord-334550-xb0alubj 29 27 and and CC cord-334550-xb0alubj 29 28 host host NN cord-334550-xb0alubj 29 29 are be VBP cord-334550-xb0alubj 29 30 brought bring VBN cord-334550-xb0alubj 29 31 together together RB cord-334550-xb0alubj 29 32 , , , cord-334550-xb0alubj 29 33 causing cause VBG cord-334550-xb0alubj 29 34 the the DT cord-334550-xb0alubj 29 35 disease disease NN cord-334550-xb0alubj 29 36 to to TO cord-334550-xb0alubj 29 37 occur occur VB cord-334550-xb0alubj 29 38 in in IN cord-334550-xb0alubj 29 39 the the DT cord-334550-xb0alubj 29 40 host host NN cord-334550-xb0alubj 29 41 . . . cord-334550-xb0alubj 30 1 Little little JJ cord-334550-xb0alubj 30 2 is be VBZ cord-334550-xb0alubj 30 3 known know VBN cord-334550-xb0alubj 30 4 regarding regard VBG cord-334550-xb0alubj 30 5 the the DT cord-334550-xb0alubj 30 6 origin origin NN cord-334550-xb0alubj 30 7 of of IN cord-334550-xb0alubj 30 8 SARS SARS NNP cord-334550-xb0alubj 30 9 - - HYPH cord-334550-xb0alubj 30 10 CoV-2 CoV-2 NNP cord-334550-xb0alubj 30 11 . . . cord-334550-xb0alubj 31 1 There there EX cord-334550-xb0alubj 31 2 have have VBP cord-334550-xb0alubj 31 3 been be VBN cord-334550-xb0alubj 31 4 speculations speculation NNS cord-334550-xb0alubj 31 5 that that IN cord-334550-xb0alubj 31 6 the the DT cord-334550-xb0alubj 31 7 virus virus NN cord-334550-xb0alubj 31 8 got get VBD cord-334550-xb0alubj 31 9 transmitted transmit VBN cord-334550-xb0alubj 31 10 to to IN cord-334550-xb0alubj 31 11 humans human NNS cord-334550-xb0alubj 31 12 from from IN cord-334550-xb0alubj 31 13 bats bat NNS cord-334550-xb0alubj 31 14 or or CC cord-334550-xb0alubj 31 15 pangolins pangolin NNS cord-334550-xb0alubj 31 16 , , , cord-334550-xb0alubj 31 17 but but CC cord-334550-xb0alubj 31 18 conclusive conclusive JJ cord-334550-xb0alubj 31 19 evidence evidence NN cord-334550-xb0alubj 31 20 regarding regard VBG cord-334550-xb0alubj 31 21 the the DT cord-334550-xb0alubj 31 22 same same JJ cord-334550-xb0alubj 31 23 is be VBZ cord-334550-xb0alubj 31 24 lacking lack VBG cord-334550-xb0alubj 31 25 . . . cord-334550-xb0alubj 32 1 Genomic genomic JJ cord-334550-xb0alubj 32 2 sequence sequence NN cord-334550-xb0alubj 32 3 data datum NNS cord-334550-xb0alubj 32 4 indicate indicate VBP cord-334550-xb0alubj 32 5 that that IN cord-334550-xb0alubj 32 6 SARS SARS NNP cord-334550-xb0alubj 32 7 - - HYPH cord-334550-xb0alubj 32 8 CoV-2 CoV-2 NNP cord-334550-xb0alubj 32 9 has have VBZ cord-334550-xb0alubj 32 10 96.2 96.2 CD cord-334550-xb0alubj 32 11 % % NN cord-334550-xb0alubj 32 12 sequence sequence NN cord-334550-xb0alubj 32 13 homology homology NN cord-334550-xb0alubj 32 14 with with IN cord-334550-xb0alubj 32 15 a a DT cord-334550-xb0alubj 32 16 bat bat NN cord-334550-xb0alubj 32 17 coronavirus coronavirus NN cord-334550-xb0alubj 32 18 RaTG13 RaTG13 . cord-334550-xb0alubj 33 1 ( ( -LRB- cord-334550-xb0alubj 33 2 Zheng Zheng NNP cord-334550-xb0alubj 33 3 , , , cord-334550-xb0alubj 33 4 2020 2020 CD cord-334550-xb0alubj 33 5 ) ) -RRB- cord-334550-xb0alubj 33 6 , , , cord-334550-xb0alubj 33 7 and and CC cord-334550-xb0alubj 33 8 91 91 CD cord-334550-xb0alubj 33 9 % % NN cord-334550-xb0alubj 33 10 homology homology NN cord-334550-xb0alubj 33 11 with with IN cord-334550-xb0alubj 33 12 a a DT cord-334550-xb0alubj 33 13 pangolin pangolin NN cord-334550-xb0alubj 33 14 coronavirus coronavirus NN cord-334550-xb0alubj 33 15 ( ( -LRB- cord-334550-xb0alubj 33 16 Zhang Zhang NNP cord-334550-xb0alubj 33 17 et et NNP cord-334550-xb0alubj 33 18 al al NNP cord-334550-xb0alubj 33 19 . . NNP cord-334550-xb0alubj 33 20 , , , cord-334550-xb0alubj 33 21 2020 2020 CD cord-334550-xb0alubj 33 22 ) ) -RRB- cord-334550-xb0alubj 33 23 . . . cord-334550-xb0alubj 34 1 Besides besides RB cord-334550-xb0alubj 34 2 , , , cord-334550-xb0alubj 34 3 it -PRON- PRP cord-334550-xb0alubj 34 4 also also RB cord-334550-xb0alubj 34 5 shares share VBZ cord-334550-xb0alubj 34 6 79.5 79.5 CD cord-334550-xb0alubj 34 7 % % NN cord-334550-xb0alubj 34 8 identity identity NN cord-334550-xb0alubj 34 9 with with IN cord-334550-xb0alubj 34 10 SARS SARS NNP cord-334550-xb0alubj 34 11 - - HYPH cord-334550-xb0alubj 34 12 CoV CoV NNP cord-334550-xb0alubj 34 13 ( ( -LRB- cord-334550-xb0alubj 34 14 Zheng Zheng NNP cord-334550-xb0alubj 34 15 , , , cord-334550-xb0alubj 34 16 2020 2020 CD cord-334550-xb0alubj 34 17 ) ) -RRB- cord-334550-xb0alubj 34 18 . . . cord-334550-xb0alubj 35 1 A a DT cord-334550-xb0alubj 35 2 recent recent JJ cord-334550-xb0alubj 35 3 study study NN cord-334550-xb0alubj 35 4 suggests suggest VBZ cord-334550-xb0alubj 35 5 that that IN cord-334550-xb0alubj 35 6 pangolins pangolin NNS cord-334550-xb0alubj 35 7 are be VBP cord-334550-xb0alubj 35 8 the the DT cord-334550-xb0alubj 35 9 natural natural JJ cord-334550-xb0alubj 35 10 reservoirs reservoir NNS cord-334550-xb0alubj 35 11 of of IN cord-334550-xb0alubj 35 12 SARS SARS NNP cord-334550-xb0alubj 35 13 - - HYPH cord-334550-xb0alubj 35 14 CoV-2-like cov-2-like JJ cord-334550-xb0alubj 35 15 coronavirus coronavirus NN cord-334550-xb0alubj 35 16 , , , cord-334550-xb0alubj 35 17 with with IN cord-334550-xb0alubj 35 18 the the DT cord-334550-xb0alubj 35 19 Pangolin Pangolin NNP cord-334550-xb0alubj 35 20 - - HYPH cord-334550-xb0alubj 35 21 CoV CoV NNP cord-334550-xb0alubj 35 22 having have VBG cord-334550-xb0alubj 35 23 a a DT cord-334550-xb0alubj 35 24 more more RBR cord-334550-xb0alubj 35 25 closely closely RB cord-334550-xb0alubj 35 26 related relate VBN cord-334550-xb0alubj 35 27 S1 s1 NN cord-334550-xb0alubj 35 28 protein protein NN cord-334550-xb0alubj 35 29 to to IN cord-334550-xb0alubj 35 30 that that DT cord-334550-xb0alubj 35 31 of of IN cord-334550-xb0alubj 35 32 SARS SARS NNP cord-334550-xb0alubj 35 33 - - HYPH cord-334550-xb0alubj 35 34 CoV-2 CoV-2 NNP cord-334550-xb0alubj 36 1 ( ( -LRB- cord-334550-xb0alubj 36 2 Zhang Zhang NNP cord-334550-xb0alubj 36 3 et et NNP cord-334550-xb0alubj 36 4 al al NNP cord-334550-xb0alubj 36 5 . . NNP cord-334550-xb0alubj 36 6 , , , cord-334550-xb0alubj 36 7 2020 2020 CD cord-334550-xb0alubj 36 8 ) ) -RRB- cord-334550-xb0alubj 36 9 . . . cord-334550-xb0alubj 37 1 It -PRON- PRP cord-334550-xb0alubj 37 2 is be VBZ cord-334550-xb0alubj 37 3 unclear unclear JJ cord-334550-xb0alubj 37 4 how how WRB cord-334550-xb0alubj 37 5 the the DT cord-334550-xb0alubj 37 6 animal animal NN cord-334550-xb0alubj 37 7 - - HYPH cord-334550-xb0alubj 37 8 to to IN cord-334550-xb0alubj 37 9 - - HYPH cord-334550-xb0alubj 37 10 human human JJ cord-334550-xb0alubj 37 11 transmission transmission NN cord-334550-xb0alubj 37 12 occurred occur VBD cord-334550-xb0alubj 37 13 and and CC cord-334550-xb0alubj 37 14 whether whether IN cord-334550-xb0alubj 37 15 the the DT cord-334550-xb0alubj 37 16 virus virus NN cord-334550-xb0alubj 37 17 acquired acquire VBD cord-334550-xb0alubj 37 18 greater great JJR cord-334550-xb0alubj 37 19 pathogenic pathogenic JJ cord-334550-xb0alubj 37 20 potential potential NN cord-334550-xb0alubj 37 21 and and CC cord-334550-xb0alubj 37 22 transmissibility transmissibility NN cord-334550-xb0alubj 37 23 after after IN cord-334550-xb0alubj 37 24 having have VBG cord-334550-xb0alubj 37 25 entered enter VBN cord-334550-xb0alubj 37 26 the the DT cord-334550-xb0alubj 37 27 human human JJ cord-334550-xb0alubj 37 28 host host NN cord-334550-xb0alubj 37 29 . . . cord-334550-xb0alubj 38 1 More More JJR cord-334550-xb0alubj 38 2 studies study NNS cord-334550-xb0alubj 38 3 need need VBP cord-334550-xb0alubj 38 4 to to TO cord-334550-xb0alubj 38 5 be be VB cord-334550-xb0alubj 38 6 focussed focusse VBN cord-334550-xb0alubj 38 7 in in IN cord-334550-xb0alubj 38 8 this this DT cord-334550-xb0alubj 38 9 aspect aspect NN cord-334550-xb0alubj 38 10 for for IN cord-334550-xb0alubj 38 11 better well JJR cord-334550-xb0alubj 38 12 understanding understanding NN cord-334550-xb0alubj 38 13 of of IN cord-334550-xb0alubj 38 14 the the DT cord-334550-xb0alubj 38 15 pathogenicity pathogenicity NN cord-334550-xb0alubj 38 16 . . . cord-334550-xb0alubj 39 1 The the DT cord-334550-xb0alubj 39 2 pandemic pandemic NN cord-334550-xb0alubj 39 3 has have VBZ cord-334550-xb0alubj 39 4 made make VBN cord-334550-xb0alubj 39 5 a a DT cord-334550-xb0alubj 39 6 considerable considerable JJ cord-334550-xb0alubj 39 7 impact impact NN cord-334550-xb0alubj 39 8 on on IN cord-334550-xb0alubj 39 9 health health NN cord-334550-xb0alubj 39 10 - - HYPH cord-334550-xb0alubj 39 11 care care NN cord-334550-xb0alubj 39 12 infrastructure infrastructure NN cord-334550-xb0alubj 39 13 worldwide worldwide RB cord-334550-xb0alubj 39 14 , , , cord-334550-xb0alubj 39 15 with with IN cord-334550-xb0alubj 39 16 medical medical JJ cord-334550-xb0alubj 39 17 facilities facility NNS cord-334550-xb0alubj 39 18 struggling struggle VBG cord-334550-xb0alubj 39 19 to to TO cord-334550-xb0alubj 39 20 cope cope VB cord-334550-xb0alubj 39 21 - - HYPH cord-334550-xb0alubj 39 22 up up NN cord-334550-xb0alubj 39 23 with with IN cord-334550-xb0alubj 39 24 the the DT cord-334550-xb0alubj 39 25 increased increase VBN cord-334550-xb0alubj 39 26 demands demand NNS cord-334550-xb0alubj 39 27 for for IN cord-334550-xb0alubj 39 28 life life NN cord-334550-xb0alubj 39 29 - - HYPH cord-334550-xb0alubj 39 30 saving save VBG cord-334550-xb0alubj 39 31 medicines medicine NNS cord-334550-xb0alubj 39 32 , , , cord-334550-xb0alubj 39 33 ventilators ventilator NNS cord-334550-xb0alubj 39 34 and and CC cord-334550-xb0alubj 39 35 personal personal JJ cord-334550-xb0alubj 39 36 protective protective JJ cord-334550-xb0alubj 39 37 equipments equipment NNS cord-334550-xb0alubj 39 38 . . . cord-334550-xb0alubj 40 1 1 1 LS cord-334550-xb0alubj 40 2 World World NNP cord-334550-xb0alubj 40 3 Health Health NNP cord-334550-xb0alubj 40 4 Organization Organization NNP cord-334550-xb0alubj 40 5 ( ( -LRB- cord-334550-xb0alubj 40 6 WHO who WP cord-334550-xb0alubj 40 7 ) ) -RRB- cord-334550-xb0alubj 40 8 Emergency Emergency NNP cord-334550-xb0alubj 40 9 Committee Committee NNP cord-334550-xb0alubj 40 10 . . . cord-334550-xb0alubj 41 1 Statement statement NN cord-334550-xb0alubj 41 2 on on IN cord-334550-xb0alubj 41 3 the the DT cord-334550-xb0alubj 41 4 second second JJ cord-334550-xb0alubj 41 5 meeting meeting NN cord-334550-xb0alubj 41 6 of of IN cord-334550-xb0alubj 41 7 the the DT cord-334550-xb0alubj 41 8 International International NNP cord-334550-xb0alubj 41 9 Health Health NNP cord-334550-xb0alubj 41 10 Regulations Regulations NNPS cord-334550-xb0alubj 41 11 ( ( -LRB- cord-334550-xb0alubj 41 12 2005 2005 CD cord-334550-xb0alubj 41 13 ) ) -RRB- cord-334550-xb0alubj 42 1 Emergency Emergency NNP cord-334550-xb0alubj 42 2 Committee Committee NNP cord-334550-xb0alubj 42 3 regarding regard VBG cord-334550-xb0alubj 42 4 the the DT cord-334550-xb0alubj 42 5 outbreak outbreak NN cord-334550-xb0alubj 42 6 of of IN cord-334550-xb0alubj 42 7 novel novel JJ cord-334550-xb0alubj 42 8 coronavirus coronavirus NN cord-334550-xb0alubj 42 9 ( ( -LRB- cord-334550-xb0alubj 42 10 2019-nCoV 2019-ncov CD cord-334550-xb0alubj 42 11 ) ) -RRB- cord-334550-xb0alubj 42 12 . . . cord-334550-xb0alubj 43 1 Geneva Geneva NNP cord-334550-xb0alubj 43 2 : : : cord-334550-xb0alubj 43 3 WHO who WP cord-334550-xb0alubj 43 4 ; ; : cord-334550-xb0alubj 43 5 30 30 CD cord-334550-xb0alubj 43 6 January January NNP cord-334550-xb0alubj 43 7 2020 2020 CD cord-334550-xb0alubj 43 8 . . . cord-334550-xb0alubj 44 1 Available available JJ cord-334550-xb0alubj 44 2 from from IN cord-334550-xb0alubj 44 3 : : : cord-334550-xb0alubj 44 4 https://www.who.int/news-room/detail/ https://www.who.int/news-room/detail/ NNP cord-334550-xb0alubj 44 5 30 30 CD cord-334550-xb0alubj 44 6 - - HYPH cord-334550-xb0alubj 44 7 01 01 CD cord-334550-xb0alubj 44 8 - - HYPH cord-334550-xb0alubj 44 9 2020-statement 2020-statement CD cord-334550-xb0alubj 44 10 - - HYPH cord-334550-xb0alubj 44 11 on on IN cord-334550-xb0alubj 44 12 - - HYPH cord-334550-xb0alubj 44 13 the the DT cord-334550-xb0alubj 44 14 - - HYPH cord-334550-xb0alubj 44 15 second second NN cord-334550-xb0alubj 44 16 - - HYPH cord-334550-xb0alubj 44 17 meeting meeting NN cord-334550-xb0alubj 44 18 - - HYPH cord-334550-xb0alubj 44 19 of of IN cord-334550-xb0alubj 44 20 - - HYPH cord-334550-xb0alubj 44 21 the the DT cord-334550-xb0alubj 44 22 - - HYPH cord-334550-xb0alubj 44 23 international international JJ cord-334550-xb0alubj 44 24 - - HYPH cord-334550-xb0alubj 44 25 healthregulations-(2005)-emergency healthregulations-(2005)-emergency NNP cord-334550-xb0alubj 44 26 - - HYPH cord-334550-xb0alubj 44 27 committee committee NN cord-334550-xb0alubj 44 28 - - HYPH cord-334550-xb0alubj 44 29 regarding regard VBG cord-334550-xb0alubj 44 30 - - HYPH cord-334550-xb0alubj 44 31 the the DT cord-334550-xb0alubj 44 32 - - HYPH cord-334550-xb0alubj 44 33 outbreak outbreak NN cord-334550-xb0alubj 44 34 - - HYPH cord-334550-xb0alubj 44 35 of of IN cord-334550-xb0alubj 44 36 - - HYPH cord-334550-xb0alubj 44 37 novelcoronavirus-(2019-ncov novelcoronavirus-(2019-ncov NN cord-334550-xb0alubj 44 38 ) ) -RRB- cord-334550-xb0alubj 45 1 ( ( -LRB- cord-334550-xb0alubj 45 2 Accessed Accessed NNP cord-334550-xb0alubj 45 3 May May NNP cord-334550-xb0alubj 45 4 25 25 CD cord-334550-xb0alubj 45 5 , , , cord-334550-xb0alubj 45 6 2020 2020 CD cord-334550-xb0alubj 45 7 ) ) -RRB- cord-334550-xb0alubj 45 8 . . . cord-334550-xb0alubj 46 1 2 2 LS cord-334550-xb0alubj 46 2 World World NNP cord-334550-xb0alubj 46 3 Health Health NNP cord-334550-xb0alubj 46 4 Organization Organization NNP cord-334550-xb0alubj 46 5 ( ( -LRB- cord-334550-xb0alubj 46 6 WHO who WP cord-334550-xb0alubj 46 7 ) ) -RRB- cord-334550-xb0alubj 46 8 Emergency Emergency NNP cord-334550-xb0alubj 46 9 Committee Committee NNP cord-334550-xb0alubj 46 10 . . . cord-334550-xb0alubj 47 1 WHO who WP cord-334550-xb0alubj 47 2 Director Director NNP cord-334550-xb0alubj 47 3 - - HYPH cord-334550-xb0alubj 47 4 General General NNP cord-334550-xb0alubj 47 5 's 's POS cord-334550-xb0alubj 47 6 opening opening NN cord-334550-xb0alubj 47 7 remarks remark NNS cord-334550-xb0alubj 47 8 at at IN cord-334550-xb0alubj 47 9 the the DT cord-334550-xb0alubj 47 10 media medium NNS cord-334550-xb0alubj 47 11 briefing briefing NN cord-334550-xb0alubj 47 12 on on IN cord-334550-xb0alubj 47 13 COVID-19 COVID-19 NNP cord-334550-xb0alubj 47 14 -11 -11 NNP cord-334550-xb0alubj 47 15 March March NNP cord-334550-xb0alubj 47 16 2020 2020 CD cord-334550-xb0alubj 47 17 . . . cord-334550-xb0alubj 48 1 Geneva Geneva NNP cord-334550-xb0alubj 48 2 : : : cord-334550-xb0alubj 48 3 WHO who WP cord-334550-xb0alubj 48 4 ; ; : cord-334550-xb0alubj 48 5 11 11 CD cord-334550-xb0alubj 48 6 March March NNP cord-334550-xb0alubj 48 7 2020 2020 CD cord-334550-xb0alubj 48 8 . . . cord-334550-xb0alubj 49 1 Available available JJ cord-334550-xb0alubj 49 2 from from IN cord-334550-xb0alubj 49 3 : : : cord-334550-xb0alubj 49 4 https https NNP cord-334550-xb0alubj 49 5 : : : cord-334550-xb0alubj 49 6 //www.who.int //www.who.int . cord-334550-xb0alubj 49 7 / / SYM cord-334550-xb0alubj 49 8 dg dg NNS cord-334550-xb0alubj 49 9 / / SYM cord-334550-xb0alubj 49 10 speeches speech NNS cord-334550-xb0alubj 49 11 / / SYM cord-334550-xb0alubj 49 12 detail detail NN cord-334550-xb0alubj 49 13 / / SYM cord-334550-xb0alubj 49 14 who who WP cord-334550-xb0alubj 49 15 - - HYPH cord-334550-xb0alubj 49 16 director director NN cord-334550-xb0alubj 49 17 - - HYPH cord-334550-xb0alubj 49 18 general general JJ cord-334550-xb0alubj 49 19 - - HYPH cord-334550-xb0alubj 49 20 s s NN cord-334550-xb0alubj 49 21 - - HYPH cord-334550-xb0alubj 49 22 opening open VBG cord-334550-xb0alubj 49 23 - - HYPH cord-334550-xb0alubj 49 24 remarks remark NNS cord-334550-xb0alubj 49 25 - - HYPH cord-334550-xb0alubj 49 26 atthe atthe JJ cord-334550-xb0alubj 49 27 - - HYPH cord-334550-xb0alubj 49 28 media media NN cord-334550-xb0alubj 49 29 - - HYPH cord-334550-xb0alubj 49 30 briefing briefing NN cord-334550-xb0alubj 49 31 - - HYPH cord-334550-xb0alubj 49 32 on on IN cord-334550-xb0alubj 49 33 - - HYPH cord-334550-xb0alubj 49 34 covid-19 covid-19 NN cord-334550-xb0alubj 49 35 - - HYPH cord-334550-xb0alubj 49 36 --11-march-2020 --11-march-2020 CD cord-334550-xb0alubj 50 1 ( ( -LRB- cord-334550-xb0alubj 50 2 Accessed Accessed NNP cord-334550-xb0alubj 50 3 May May NNP cord-334550-xb0alubj 50 4 25 25 CD cord-334550-xb0alubj 50 5 , , , cord-334550-xb0alubj 50 6 2020 2020 CD cord-334550-xb0alubj 50 7 ) ) -RRB- cord-334550-xb0alubj 50 8 . . . cord-334550-xb0alubj 51 1 3 3 LS cord-334550-xb0alubj 51 2 World World NNP cord-334550-xb0alubj 51 3 Health Health NNP cord-334550-xb0alubj 51 4 Organization Organization NNP cord-334550-xb0alubj 51 5 ( ( -LRB- cord-334550-xb0alubj 51 6 WHO who WP cord-334550-xb0alubj 51 7 ) ) -RRB- cord-334550-xb0alubj 51 8 . . . cord-334550-xb0alubj 52 1 Coronavirus Coronavirus NNP cord-334550-xb0alubj 52 2 disease disease NN cord-334550-xb0alubj 52 3 ( ( -LRB- cord-334550-xb0alubj 52 4 COVID-19 COVID-19 NNP cord-334550-xb0alubj 52 5 ) ) -RRB- cord-334550-xb0alubj 52 6 : : : cord-334550-xb0alubj 53 1 situation situation NN cord-334550-xb0alubj 53 2 report report NN cord-334550-xb0alubj 53 3 , , , cord-334550-xb0alubj 53 4 165 165 CD cord-334550-xb0alubj 53 5 . . . cord-334550-xb0alubj 54 1 Geneva Geneva NNP cord-334550-xb0alubj 54 2 : : : cord-334550-xb0alubj 54 3 WHO who WP cord-334550-xb0alubj 54 4 ; ; : cord-334550-xb0alubj 54 5 03 03 CD cord-334550-xb0alubj 54 6 July July NNP cord-334550-xb0alubj 54 7 2020 2020 CD cord-334550-xb0alubj 54 8 . . . cord-334550-xb0alubj 55 1 Available available JJ cord-334550-xb0alubj 55 2 from from IN cord-334550-xb0alubj 55 3 : : : cord-334550-xb0alubj 55 4 https https NNP cord-334550-xb0alubj 55 5 : : : cord-334550-xb0alubj 55 6 //www.who.int //www.who.int . cord-334550-xb0alubj 55 7 / / SYM cord-334550-xb0alubj 55 8 emergencies emergency NNS cord-334550-xb0alubj 55 9 / / SYM cord-334550-xb0alubj 55 10 diseases disease NNS cord-334550-xb0alubj 55 11 / / SYM cord-334550-xb0alubj 55 12 novel novel NN cord-334550-xb0alubj 55 13 - - HYPH cord-334550-xb0alubj 55 14 coronavirus-2019 coronavirus-2019 NN cord-334550-xb0alubj 55 15 / / SYM cord-334550-xb0alubj 55 16 situation situation NN cord-334550-xb0alubj 55 17 - - : cord-334550-xb0alubj 55 18 reports/ reports/ . cord-334550-xb0alubj 56 1 ( ( -LRB- cord-334550-xb0alubj 56 2 Accessed access VBN cord-334550-xb0alubj 56 3 July July NNP cord-334550-xb0alubj 56 4 3 3 CD cord-334550-xb0alubj 56 5 , , , cord-334550-xb0alubj 56 6 2020 2020 CD cord-334550-xb0alubj 56 7 ) ) -RRB- cord-334550-xb0alubj 56 8 . . . cord-334550-xb0alubj 57 1 Despite despite IN cord-334550-xb0alubj 57 2 the the DT cord-334550-xb0alubj 57 3 catastrophic catastrophic JJ cord-334550-xb0alubj 57 4 consequences consequence NNS cord-334550-xb0alubj 57 5 of of IN cord-334550-xb0alubj 57 6 this this DT cord-334550-xb0alubj 57 7 pandemic pandemic NN cord-334550-xb0alubj 57 8 on on IN cord-334550-xb0alubj 57 9 several several JJ cord-334550-xb0alubj 57 10 affluent affluent JJ cord-334550-xb0alubj 57 11 nations nation NNS cord-334550-xb0alubj 57 12 , , , cord-334550-xb0alubj 57 13 its -PRON- PRP$ cord-334550-xb0alubj 57 14 impact impact NN cord-334550-xb0alubj 57 15 on on IN cord-334550-xb0alubj 57 16 Indian indian JJ cord-334550-xb0alubj 57 17 population population NN cord-334550-xb0alubj 57 18 seems seem VBZ cord-334550-xb0alubj 57 19 to to TO cord-334550-xb0alubj 57 20 be be VB cord-334550-xb0alubj 57 21 much much RB cord-334550-xb0alubj 57 22 lower low JJR cord-334550-xb0alubj 57 23 both both CC cord-334550-xb0alubj 57 24 in in IN cord-334550-xb0alubj 57 25 terms term NNS cord-334550-xb0alubj 57 26 of of IN cord-334550-xb0alubj 57 27 severity severity NN cord-334550-xb0alubj 57 28 as as RB cord-334550-xb0alubj 57 29 well well RB cord-334550-xb0alubj 57 30 as as IN cord-334550-xb0alubj 57 31 CFR CFR NNP cord-334550-xb0alubj 57 32 . . . cord-334550-xb0alubj 58 1 Of of IN cord-334550-xb0alubj 58 2 the the DT cord-334550-xb0alubj 58 3 total total JJ cord-334550-xb0alubj 58 4 227,439 227,439 CD cord-334550-xb0alubj 58 5 active active JJ cord-334550-xb0alubj 58 6 cases case NNS cord-334550-xb0alubj 58 7 of of IN cord-334550-xb0alubj 58 8 COVID-19 covid-19 CD cord-334550-xb0alubj 58 9 till till IN cord-334550-xb0alubj 58 10 July July NNP cord-334550-xb0alubj 58 11 03 03 CD cord-334550-xb0alubj 58 12 , , , cord-334550-xb0alubj 58 13 2020 2020 CD cord-334550-xb0alubj 58 14 in in IN cord-334550-xb0alubj 58 15 India India NNP cord-334550-xb0alubj 58 16 , , , cord-334550-xb0alubj 58 17 15.3 15.3 CD cord-334550-xb0alubj 58 18 % % NN cord-334550-xb0alubj 58 19 required require VBD cord-334550-xb0alubj 58 20 ICU ICU NNP cord-334550-xb0alubj 58 21 admission admission NN cord-334550-xb0alubj 58 22 , , , cord-334550-xb0alubj 58 23 4.16 4.16 CD cord-334550-xb0alubj 58 24 % % NN cord-334550-xb0alubj 58 25 required require VBN cord-334550-xb0alubj 58 26 ventilator ventilator NN cord-334550-xb0alubj 58 27 support support NN cord-334550-xb0alubj 58 28 and and CC cord-334550-xb0alubj 58 29 15.9 15.9 CD cord-334550-xb0alubj 58 30 % % NN cord-334550-xb0alubj 58 31 required require VBD cord-334550-xb0alubj 58 32 supplemental supplemental JJ cord-334550-xb0alubj 58 33 oxygen oxygen NN cord-334550-xb0alubj 58 34 , , , cord-334550-xb0alubj 58 35 all all DT cord-334550-xb0alubj 58 36 of of IN cord-334550-xb0alubj 58 37 which which WDT cord-334550-xb0alubj 58 38 point point VBP cord-334550-xb0alubj 58 39 toward toward IN cord-334550-xb0alubj 58 40 a a DT cord-334550-xb0alubj 58 41 less less RBR cord-334550-xb0alubj 58 42 severe severe JJ cord-334550-xb0alubj 58 43 disease disease NN cord-334550-xb0alubj 58 44 among among IN cord-334550-xb0alubj 58 45 Indians Indians NNPS cord-334550-xb0alubj 58 46 . . . cord-334550-xb0alubj 59 1 4 4 LS cord-334550-xb0alubj 60 1 So so CC cord-334550-xb0alubj 60 2 what what WP cord-334550-xb0alubj 60 3 is be VBZ cord-334550-xb0alubj 60 4 that that IN cord-334550-xb0alubj 60 5 " " `` cord-334550-xb0alubj 60 6 X x NN cord-334550-xb0alubj 60 7 " " '' cord-334550-xb0alubj 60 8 factor factor NN cord-334550-xb0alubj 60 9 apparently apparently RB cord-334550-xb0alubj 60 10 safeguarding safeguard VBG cord-334550-xb0alubj 60 11 the the DT cord-334550-xb0alubj 60 12 Indian indian JJ cord-334550-xb0alubj 60 13 population population NN cord-334550-xb0alubj 60 14 from from IN cord-334550-xb0alubj 60 15 the the DT cord-334550-xb0alubj 60 16 wrath wrath NN cord-334550-xb0alubj 60 17 of of IN cord-334550-xb0alubj 60 18 this this DT cord-334550-xb0alubj 60 19 pandemic pandemic NN cord-334550-xb0alubj 60 20 ? ? . cord-334550-xb0alubj 61 1 This this DT cord-334550-xb0alubj 61 2 perspective perspective NN cord-334550-xb0alubj 61 3 provides provide VBZ cord-334550-xb0alubj 61 4 an an DT cord-334550-xb0alubj 61 5 insight insight NN cord-334550-xb0alubj 61 6 into into IN cord-334550-xb0alubj 61 7 the the DT cord-334550-xb0alubj 61 8 potential potential JJ cord-334550-xb0alubj 61 9 factors factor NNS cord-334550-xb0alubj 61 10 that that WDT cord-334550-xb0alubj 61 11 might may MD cord-334550-xb0alubj 61 12 be be VB cord-334550-xb0alubj 61 13 responsible responsible JJ cord-334550-xb0alubj 61 14 for for IN cord-334550-xb0alubj 61 15 the the DT cord-334550-xb0alubj 61 16 observed observed JJ cord-334550-xb0alubj 61 17 low low JJ cord-334550-xb0alubj 61 18 COVID-19 covid-19 JJ cord-334550-xb0alubj 61 19 severity severity NN cord-334550-xb0alubj 61 20 and and CC cord-334550-xb0alubj 61 21 fatality fatality NN cord-334550-xb0alubj 61 22 rate rate NN cord-334550-xb0alubj 61 23 in in IN cord-334550-xb0alubj 61 24 Indian indian JJ cord-334550-xb0alubj 61 25 population population NN cord-334550-xb0alubj 61 26 and and CC cord-334550-xb0alubj 61 27 illuminates illuminate VBZ cord-334550-xb0alubj 61 28 the the DT cord-334550-xb0alubj 61 29 areas area NNS cord-334550-xb0alubj 61 30 of of IN cord-334550-xb0alubj 61 31 future future JJ cord-334550-xb0alubj 61 32 research research NN cord-334550-xb0alubj 61 33 which which WDT cord-334550-xb0alubj 61 34 may may MD cord-334550-xb0alubj 61 35 help help VB cord-334550-xb0alubj 61 36 in in IN cord-334550-xb0alubj 61 37 understanding understand VBG cord-334550-xb0alubj 61 38 the the DT cord-334550-xb0alubj 61 39 disease disease NN cord-334550-xb0alubj 61 40 process process NN cord-334550-xb0alubj 61 41 more more RBR cord-334550-xb0alubj 61 42 vividly vividly RB cord-334550-xb0alubj 61 43 . . . cord-334550-xb0alubj 62 1 How how WRB cord-334550-xb0alubj 62 2 Do do VBP cord-334550-xb0alubj 62 3 the the DT cord-334550-xb0alubj 62 4 Indian indian JJ cord-334550-xb0alubj 62 5 SARS SARS NNP cord-334550-xb0alubj 62 6 - - HYPH cord-334550-xb0alubj 62 7 CoV-2 CoV-2 NNP cord-334550-xb0alubj 62 8 Strains strain NNS cord-334550-xb0alubj 62 9 Differ differ VBP cord-334550-xb0alubj 62 10 From from IN cord-334550-xb0alubj 62 11 the the DT cord-334550-xb0alubj 62 12 Strains strain NNS cord-334550-xb0alubj 62 13 Elsewhere elsewhere RB cord-334550-xb0alubj 62 14 ? ? . cord-334550-xb0alubj 63 1 Earlier early RBR cord-334550-xb0alubj 63 2 , , , cord-334550-xb0alubj 63 3 six six CD cord-334550-xb0alubj 63 4 genera genus NNS cord-334550-xb0alubj 63 5 of of IN cord-334550-xb0alubj 63 6 coronaviruses coronaviruse NNS cord-334550-xb0alubj 63 7 were be VBD cord-334550-xb0alubj 63 8 known know VBN cord-334550-xb0alubj 63 9 to to TO cord-334550-xb0alubj 63 10 cause cause VB cord-334550-xb0alubj 63 11 human human JJ cord-334550-xb0alubj 63 12 disease disease NN cord-334550-xb0alubj 63 13 , , , cord-334550-xb0alubj 63 14 of of IN cord-334550-xb0alubj 63 15 which which WDT cord-334550-xb0alubj 63 16 four four CD cord-334550-xb0alubj 63 17 ( ( -LRB- cord-334550-xb0alubj 63 18 α α NNP cord-334550-xb0alubj 63 19 - - HYPH cord-334550-xb0alubj 63 20 CoV-229E CoV-229E NNP cord-334550-xb0alubj 63 21 and and CC cord-334550-xb0alubj 63 22 NL63 NL63 NNP cord-334550-xb0alubj 63 23 , , , cord-334550-xb0alubj 63 24 and and CC cord-334550-xb0alubj 63 25 β β NN cord-334550-xb0alubj 63 26 - - HYPH cord-334550-xb0alubj 63 27 CoV CoV NNP cord-334550-xb0alubj 63 28 - - HYPH cord-334550-xb0alubj 63 29 HKU1 HKU1 NNP cord-334550-xb0alubj 63 30 and and CC cord-334550-xb0alubj 63 31 OC43 OC43 NNP cord-334550-xb0alubj 63 32 ) ) -RRB- cord-334550-xb0alubj 63 33 are be VBP cord-334550-xb0alubj 63 34 responsible responsible JJ cord-334550-xb0alubj 63 35 for for IN cord-334550-xb0alubj 63 36 mild mild JJ cord-334550-xb0alubj 63 37 respiratory respiratory JJ cord-334550-xb0alubj 63 38 infections infection NNS cord-334550-xb0alubj 63 39 , , , cord-334550-xb0alubj 63 40 mostly mostly RB cord-334550-xb0alubj 63 41 in in IN cord-334550-xb0alubj 63 42 pediatric pediatric JJ cord-334550-xb0alubj 63 43 age age NN cord-334550-xb0alubj 63 44 group group NN cord-334550-xb0alubj 63 45 while while IN cord-334550-xb0alubj 63 46 two two CD cord-334550-xb0alubj 63 47 ( ( -LRB- cord-334550-xb0alubj 63 48 SARS SARS NNP cord-334550-xb0alubj 63 49 - - HYPH cord-334550-xb0alubj 63 50 CoV CoV NNP cord-334550-xb0alubj 63 51 and and CC cord-334550-xb0alubj 63 52 Middle Middle NNP cord-334550-xb0alubj 63 53 East East NNP cord-334550-xb0alubj 63 54 Respiratory Respiratory NNP cord-334550-xb0alubj 63 55 Syndrome Syndrome NNP cord-334550-xb0alubj 63 56 coronavirus coronavirus NN cord-334550-xb0alubj 63 57 [ [ -LRB- cord-334550-xb0alubj 63 58 MERS MERS NNP cord-334550-xb0alubj 63 59 CoV CoV NNP cord-334550-xb0alubj 63 60 ] ] -RRB- cord-334550-xb0alubj 63 61 ) ) -RRB- cord-334550-xb0alubj 63 62 are be VBP cord-334550-xb0alubj 63 63 associated associate VBN cord-334550-xb0alubj 63 64 with with IN cord-334550-xb0alubj 63 65 severe severe JJ cord-334550-xb0alubj 63 66 outbreaks outbreak NNS cord-334550-xb0alubj 63 67 . . . cord-334550-xb0alubj 64 1 SARS SARS NNP cord-334550-xb0alubj 64 2 - - HYPH cord-334550-xb0alubj 64 3 CoV-2 CoV-2 NNP cord-334550-xb0alubj 64 4 is be VBZ cord-334550-xb0alubj 64 5 a a DT cord-334550-xb0alubj 64 6 positive positive JJ cord-334550-xb0alubj 64 7 sense sense NN cord-334550-xb0alubj 64 8 single single RB cord-334550-xb0alubj 64 9 - - HYPH cord-334550-xb0alubj 64 10 stranded strand VBN cord-334550-xb0alubj 64 11 RNA RNA NNP cord-334550-xb0alubj 64 12 virus virus NN cord-334550-xb0alubj 64 13 harboring harbor VBG cord-334550-xb0alubj 64 14 two two CD cord-334550-xb0alubj 64 15 major major JJ cord-334550-xb0alubj 64 16 genes gene NNS cord-334550-xb0alubj 64 17 , , , cord-334550-xb0alubj 64 18 open open JJ cord-334550-xb0alubj 64 19 reading reading NN cord-334550-xb0alubj 64 20 frame frame NN cord-334550-xb0alubj 64 21 1a 1a CD cord-334550-xb0alubj 64 22 ( ( -LRB- cord-334550-xb0alubj 64 23 ORF1a ORF1a NNP cord-334550-xb0alubj 64 24 ) ) -RRB- cord-334550-xb0alubj 64 25 and and CC cord-334550-xb0alubj 64 26 ORF1b ORF1b NNP cord-334550-xb0alubj 64 27 , , , cord-334550-xb0alubj 64 28 which which WDT cord-334550-xb0alubj 64 29 together together RB cord-334550-xb0alubj 64 30 encode encode VBP cord-334550-xb0alubj 64 31 16 16 CD cord-334550-xb0alubj 64 32 non non JJ cord-334550-xb0alubj 64 33 - - JJ cord-334550-xb0alubj 64 34 structural structural JJ cord-334550-xb0alubj 64 35 proteins protein NNS cord-334550-xb0alubj 64 36 ( ( -LRB- cord-334550-xb0alubj 64 37 NSP1-NSP16 NSP1-NSP16 NNP cord-334550-xb0alubj 64 38 ) ) -RRB- cord-334550-xb0alubj 64 39 . . . cord-334550-xb0alubj 65 1 These these DT cord-334550-xb0alubj 65 2 NSPs nsp NNS cord-334550-xb0alubj 65 3 are be VBP cord-334550-xb0alubj 65 4 organized organize VBN cord-334550-xb0alubj 65 5 to to TO cord-334550-xb0alubj 65 6 form form VB cord-334550-xb0alubj 65 7 a a DT cord-334550-xb0alubj 65 8 replication replication NN cord-334550-xb0alubj 65 9 - - HYPH cord-334550-xb0alubj 65 10 transcription transcription NN cord-334550-xb0alubj 65 11 complex complex NN cord-334550-xb0alubj 65 12 ( ( -LRB- cord-334550-xb0alubj 65 13 RTC RTC NNP cord-334550-xb0alubj 65 14 ) ) -RRB- cord-334550-xb0alubj 65 15 that that WDT cord-334550-xb0alubj 65 16 is be VBZ cord-334550-xb0alubj 65 17 involved involve VBN cord-334550-xb0alubj 65 18 in in IN cord-334550-xb0alubj 65 19 transcription transcription NN cord-334550-xb0alubj 65 20 and and CC cord-334550-xb0alubj 65 21 replication replication NN cord-334550-xb0alubj 65 22 . . . cord-334550-xb0alubj 66 1 NSP3 NSP3 NNP cord-334550-xb0alubj 66 2 and and CC cord-334550-xb0alubj 66 3 NSP5 NSP5 NNP cord-334550-xb0alubj 66 4 encode encode VBP cord-334550-xb0alubj 66 5 for for IN cord-334550-xb0alubj 66 6 Papain Papain NNP cord-334550-xb0alubj 66 7 - - HYPH cord-334550-xb0alubj 66 8 like like JJ cord-334550-xb0alubj 66 9 protease protease NN cord-334550-xb0alubj 66 10 ( ( -LRB- cord-334550-xb0alubj 66 11 PLP PLP NNP cord-334550-xb0alubj 66 12 ) ) -RRB- cord-334550-xb0alubj 66 13 and and CC cord-334550-xb0alubj 66 14 Chymotrypsin Chymotrypsin NNP cord-334550-xb0alubj 66 15 - - HYPH cord-334550-xb0alubj 66 16 like like JJ cord-334550-xb0alubj 66 17 protease protease NN cord-334550-xb0alubj 66 18 ( ( -LRB- cord-334550-xb0alubj 66 19 3CL 3CL NNP cord-334550-xb0alubj 66 20 ) ) -RRB- cord-334550-xb0alubj 66 21 , , , cord-334550-xb0alubj 66 22 respectively respectively RB cord-334550-xb0alubj 66 23 , , , cord-334550-xb0alubj 66 24 which which WDT cord-334550-xb0alubj 66 25 help help VBP cord-334550-xb0alubj 66 26 in in IN cord-334550-xb0alubj 66 27 peptide peptide NN cord-334550-xb0alubj 66 28 cleaving cleaving NN cord-334550-xb0alubj 66 29 and and CC cord-334550-xb0alubj 66 30 host host NN cord-334550-xb0alubj 66 31 innate innate JJ cord-334550-xb0alubj 66 32 immune immune JJ cord-334550-xb0alubj 66 33 antagonism antagonism NN cord-334550-xb0alubj 66 34 . . . cord-334550-xb0alubj 67 1 NSP12 nsp12 NN cord-334550-xb0alubj 67 2 and and CC cord-334550-xb0alubj 67 3 NSP15 NSP15 NNP cord-334550-xb0alubj 67 4 encode encode VB cord-334550-xb0alubj 67 5 for for IN cord-334550-xb0alubj 67 6 RNA rna NN cord-334550-xb0alubj 67 7 - - HYPH cord-334550-xb0alubj 67 8 dependent dependent JJ cord-334550-xb0alubj 67 9 RNA RNA NNP cord-334550-xb0alubj 67 10 polymerase polymerase NN cord-334550-xb0alubj 67 11 ( ( -LRB- cord-334550-xb0alubj 67 12 RdRp RdRp NNP cord-334550-xb0alubj 67 13 ) ) -RRB- cord-334550-xb0alubj 67 14 and and CC cord-334550-xb0alubj 67 15 RNA RNA NNP cord-334550-xb0alubj 67 16 helicase helicase NNP cord-334550-xb0alubj 67 17 , , , cord-334550-xb0alubj 67 18 respectively respectively RB cord-334550-xb0alubj 67 19 . . . cord-334550-xb0alubj 68 1 The the DT cord-334550-xb0alubj 68 2 structural structural JJ cord-334550-xb0alubj 68 3 genes gene NNS cord-334550-xb0alubj 68 4 encode encode VBP cord-334550-xb0alubj 68 5 four four CD cord-334550-xb0alubj 68 6 structural structural JJ cord-334550-xb0alubj 68 7 proteins protein NNS cord-334550-xb0alubj 68 8 : : : cord-334550-xb0alubj 68 9 spike spike NN cord-334550-xb0alubj 68 10 ( ( -LRB- cord-334550-xb0alubj 68 11 S S NNP cord-334550-xb0alubj 68 12 ) ) -RRB- cord-334550-xb0alubj 68 13 , , , cord-334550-xb0alubj 68 14 envelope envelope NN cord-334550-xb0alubj 68 15 ( ( -LRB- cord-334550-xb0alubj 68 16 E E NNP cord-334550-xb0alubj 68 17 ) ) -RRB- cord-334550-xb0alubj 68 18 , , , cord-334550-xb0alubj 68 19 membrane membrane NN cord-334550-xb0alubj 68 20 ( ( -LRB- cord-334550-xb0alubj 68 21 M M NNP cord-334550-xb0alubj 68 22 ) ) -RRB- cord-334550-xb0alubj 68 23 , , , cord-334550-xb0alubj 68 24 and and CC cord-334550-xb0alubj 68 25 nucleocapsid nucleocapsid NN cord-334550-xb0alubj 68 26 ( ( -LRB- cord-334550-xb0alubj 68 27 N N NNP cord-334550-xb0alubj 68 28 ) ) -RRB- cord-334550-xb0alubj 68 29 , , , cord-334550-xb0alubj 68 30 and and CC cord-334550-xb0alubj 68 31 several several JJ cord-334550-xb0alubj 68 32 accessory accessory NN cord-334550-xb0alubj 68 33 proteins protein NNS cord-334550-xb0alubj 68 34 ( ( -LRB- cord-334550-xb0alubj 68 35 Astuti Astuti NNP cord-334550-xb0alubj 68 36 and and CC cord-334550-xb0alubj 68 37 Ysrafil Ysrafil NNP cord-334550-xb0alubj 68 38 , , , cord-334550-xb0alubj 68 39 2020 2020 CD cord-334550-xb0alubj 68 40 ) ) -RRB- cord-334550-xb0alubj 68 41 . . . cord-334550-xb0alubj 69 1 Molecular molecular JJ cord-334550-xb0alubj 69 2 characterization characterization NN cord-334550-xb0alubj 69 3 of of IN cord-334550-xb0alubj 69 4 SARS SARS NNP cord-334550-xb0alubj 69 5 - - HYPH cord-334550-xb0alubj 69 6 CoV-2 CoV-2 NNP cord-334550-xb0alubj 69 7 strains strain NNS cord-334550-xb0alubj 69 8 based base VBN cord-334550-xb0alubj 69 9 on on IN cord-334550-xb0alubj 69 10 whole whole JJ cord-334550-xb0alubj 69 11 - - HYPH cord-334550-xb0alubj 69 12 genome genome NN cord-334550-xb0alubj 69 13 sequencing sequencing NN cord-334550-xb0alubj 69 14 revealed reveal VBN cord-334550-xb0alubj 69 15 clustering clustering NN cord-334550-xb0alubj 69 16 of of IN cord-334550-xb0alubj 69 17 the the DT cord-334550-xb0alubj 69 18 prototype prototype NN cord-334550-xb0alubj 69 19 Wuhan Wuhan NNP cord-334550-xb0alubj 69 20 strain strain NN cord-334550-xb0alubj 69 21 belonging belong VBG cord-334550-xb0alubj 69 22 to to IN cord-334550-xb0alubj 69 23 the the DT cord-334550-xb0alubj 69 24 O o NN cord-334550-xb0alubj 69 25 clade clade NN cord-334550-xb0alubj 69 26 ( ( -LRB- cord-334550-xb0alubj 69 27 MN908947.3 MN908947.3 NNP cord-334550-xb0alubj 69 28 / / SYM cord-334550-xb0alubj 69 29 SARS SARS NNP cord-334550-xb0alubj 69 30 - - HYPH cord-334550-xb0alubj 69 31 COV-2 COV-2 NNP cord-334550-xb0alubj 69 32 / / SYM cord-334550-xb0alubj 69 33 HUMAN HUMAN NNP cord-334550-xb0alubj 69 34 / / SYM cord-334550-xb0alubj 69 35 CHN CHN NNP cord-334550-xb0alubj 69 36 / / SYM cord-334550-xb0alubj 69 37 Wuhan Wuhan NNP cord-334550-xb0alubj 69 38 - - HYPH cord-334550-xb0alubj 69 39 Hu-1/2019 Hu-1/2019 NNP cord-334550-xb0alubj 69 40 ) ) -RRB- cord-334550-xb0alubj 69 41 , , , cord-334550-xb0alubj 69 42 indicating indicate VBG cord-334550-xb0alubj 69 43 that that IN cord-334550-xb0alubj 69 44 the the DT cord-334550-xb0alubj 69 45 virus virus NN cord-334550-xb0alubj 69 46 might may MD cord-334550-xb0alubj 69 47 have have VB cord-334550-xb0alubj 69 48 originated originate VBN cord-334550-xb0alubj 69 49 in in IN cord-334550-xb0alubj 69 50 China China NNP cord-334550-xb0alubj 69 51 and and CC cord-334550-xb0alubj 69 52 eventually eventually RB cord-334550-xb0alubj 69 53 spread spread VBP cord-334550-xb0alubj 69 54 worldwide worldwide RB cord-334550-xb0alubj 69 55 Fan Fan NNP cord-334550-xb0alubj 69 56 et et NNP cord-334550-xb0alubj 69 57 al al NNP cord-334550-xb0alubj 69 58 . . NNP cord-334550-xb0alubj 69 59 , , , cord-334550-xb0alubj 69 60 2020 2020 CD cord-334550-xb0alubj 69 61 ) ) -RRB- cord-334550-xb0alubj 69 62 . . . cord-334550-xb0alubj 70 1 The the DT cord-334550-xb0alubj 70 2 Indian indian JJ cord-334550-xb0alubj 70 3 SARS SARS NNP cord-334550-xb0alubj 70 4 - - HYPH cord-334550-xb0alubj 70 5 CoV-2 CoV-2 NNP cord-334550-xb0alubj 70 6 strains strain NNS cord-334550-xb0alubj 70 7 , , , cord-334550-xb0alubj 70 8 unlike unlike IN cord-334550-xb0alubj 70 9 the the DT cord-334550-xb0alubj 70 10 strains strain NNS cord-334550-xb0alubj 70 11 elsewhere elsewhere RB cord-334550-xb0alubj 70 12 , , , cord-334550-xb0alubj 70 13 are be VBP cord-334550-xb0alubj 70 14 more more RBR cord-334550-xb0alubj 70 15 closely closely RB cord-334550-xb0alubj 70 16 related relate VBN cord-334550-xb0alubj 70 17 to to IN cord-334550-xb0alubj 70 18 bat bat NN cord-334550-xb0alubj 70 19 - - HYPH cord-334550-xb0alubj 70 20 CoV cov NN cord-334550-xb0alubj 70 21 RaTG13 ratg13 NN cord-334550-xb0alubj 71 1 ( ( -LRB- cord-334550-xb0alubj 71 2 93 93 CD cord-334550-xb0alubj 71 3 % % NN cord-334550-xb0alubj 71 4 homology homology NN cord-334550-xb0alubj 71 5 ) ) -RRB- cord-334550-xb0alubj 71 6 than than IN cord-334550-xb0alubj 71 7 pangolin pangolin NNP cord-334550-xb0alubj 71 8 CoV CoV NNP cord-334550-xb0alubj 71 9 ( ( -LRB- cord-334550-xb0alubj 71 10 83.5 83.5 CD cord-334550-xb0alubj 71 11 % % NN cord-334550-xb0alubj 71 12 homology homology NN cord-334550-xb0alubj 71 13 ) ) -RRB- cord-334550-xb0alubj 71 14 . . . cord-334550-xb0alubj 72 1 However however RB cord-334550-xb0alubj 72 2 , , , cord-334550-xb0alubj 72 3 the the DT cord-334550-xb0alubj 72 4 receptor receptor NN cord-334550-xb0alubj 72 5 binding bind VBG cord-334550-xb0alubj 72 6 domain domain NN cord-334550-xb0alubj 72 7 ( ( -LRB- cord-334550-xb0alubj 72 8 RBD RBD NNP cord-334550-xb0alubj 72 9 ) ) -RRB- cord-334550-xb0alubj 72 10 of of IN cord-334550-xb0alubj 72 11 S S NNP cord-334550-xb0alubj 72 12 protein protein NN cord-334550-xb0alubj 72 13 of of IN cord-334550-xb0alubj 72 14 Indian indian JJ cord-334550-xb0alubj 72 15 SARS SARS NNP cord-334550-xb0alubj 72 16 - - HYPH cord-334550-xb0alubj 72 17 CoV-2 CoV-2 NNP cord-334550-xb0alubj 72 18 strains strain NNS cord-334550-xb0alubj 72 19 are be VBP cord-334550-xb0alubj 72 20 more more RBR cord-334550-xb0alubj 72 21 closely closely RB cord-334550-xb0alubj 72 22 related related JJ cord-334550-xb0alubj 72 23 to to IN cord-334550-xb0alubj 72 24 pangolin pangolin NN cord-334550-xb0alubj 72 25 - - HYPH cord-334550-xb0alubj 72 26 CoV CoV NNP cord-334550-xb0alubj 73 1 ( ( -LRB- cord-334550-xb0alubj 73 2 Zhang Zhang NNP cord-334550-xb0alubj 73 3 et et NNP cord-334550-xb0alubj 73 4 al al NNP cord-334550-xb0alubj 73 5 . . NNP cord-334550-xb0alubj 73 6 , , , cord-334550-xb0alubj 73 7 2020 2020 CD cord-334550-xb0alubj 73 8 ) ) -RRB- cord-334550-xb0alubj 73 9 . . . cord-334550-xb0alubj 74 1 A a DT cord-334550-xb0alubj 74 2 recent recent JJ cord-334550-xb0alubj 74 3 study study NN cord-334550-xb0alubj 74 4 from from IN cord-334550-xb0alubj 74 5 National National NNP cord-334550-xb0alubj 74 6 Institute Institute NNP cord-334550-xb0alubj 74 7 of of IN cord-334550-xb0alubj 74 8 Cholera Cholera NNP cord-334550-xb0alubj 74 9 and and CC cord-334550-xb0alubj 74 10 Enteric Enteric NNP cord-334550-xb0alubj 74 11 Diseases Diseases NNPS cord-334550-xb0alubj 74 12 , , , cord-334550-xb0alubj 74 13 West West NNP cord-334550-xb0alubj 74 14 Bengal Bengal NNP cord-334550-xb0alubj 74 15 , , , cord-334550-xb0alubj 74 16 India India NNP cord-334550-xb0alubj 74 17 analyzed analyze VBD cord-334550-xb0alubj 74 18 the the DT cord-334550-xb0alubj 74 19 genome genome NN cord-334550-xb0alubj 74 20 type type NN cord-334550-xb0alubj 74 21 clusters cluster NNS cord-334550-xb0alubj 74 22 of of IN cord-334550-xb0alubj 74 23 46 46 CD cord-334550-xb0alubj 74 24 Indian indian JJ cord-334550-xb0alubj 74 25 SARS SARS NNP cord-334550-xb0alubj 74 26 - - HYPH cord-334550-xb0alubj 74 27 CoV-2 CoV-2 NNP cord-334550-xb0alubj 74 28 isolates isolate NNS cord-334550-xb0alubj 74 29 and and CC cord-334550-xb0alubj 74 30 observed observe VBD cord-334550-xb0alubj 74 31 a a DT cord-334550-xb0alubj 74 32 monophyletic monophyletic JJ cord-334550-xb0alubj 74 33 clade clade NN cord-334550-xb0alubj 74 34 of of IN cord-334550-xb0alubj 74 35 the the DT cord-334550-xb0alubj 74 36 virus virus NN cord-334550-xb0alubj 74 37 co co NN cord-334550-xb0alubj 74 38 - - NN cord-334550-xb0alubj 74 39 existing exist VBG cord-334550-xb0alubj 74 40 with with IN cord-334550-xb0alubj 74 41 the the DT cord-334550-xb0alubj 74 42 prototype prototype NN cord-334550-xb0alubj 74 43 Wuhan Wuhan NNP cord-334550-xb0alubj 74 44 strain strain NN cord-334550-xb0alubj 74 45 ( ( -LRB- cord-334550-xb0alubj 74 46 clade clade NN cord-334550-xb0alubj 74 47 O O NNP cord-334550-xb0alubj 74 48 ) ) -RRB- cord-334550-xb0alubj 74 49 and and CC cord-334550-xb0alubj 74 50 clustering cluster VBG cord-334550-xb0alubj 74 51 along along IN cord-334550-xb0alubj 74 52 with with IN cord-334550-xb0alubj 74 53 the the DT cord-334550-xb0alubj 74 54 Indian indian JJ cord-334550-xb0alubj 74 55 isolates isolate NNS cord-334550-xb0alubj 74 56 , , , cord-334550-xb0alubj 74 57 suggesting suggest VBG cord-334550-xb0alubj 74 58 introduction introduction NN cord-334550-xb0alubj 74 59 of of IN cord-334550-xb0alubj 74 60 the the DT cord-334550-xb0alubj 74 61 virus virus NN cord-334550-xb0alubj 74 62 in in IN cord-334550-xb0alubj 74 63 India India NNP cord-334550-xb0alubj 74 64 from from IN cord-334550-xb0alubj 74 65 several several JJ cord-334550-xb0alubj 74 66 countries country NNS cord-334550-xb0alubj 74 67 . . . cord-334550-xb0alubj 75 1 1 1 LS cord-334550-xb0alubj 75 2 | | NNP cord-334550-xb0alubj 75 3 Phylogenetics Phylogenetics NNP cord-334550-xb0alubj 75 4 clades clade NNS cord-334550-xb0alubj 75 5 of of IN cord-334550-xb0alubj 75 6 SARS SARS NNP cord-334550-xb0alubj 75 7 - - HYPH cord-334550-xb0alubj 75 8 CoV-2 CoV-2 NNP cord-334550-xb0alubj 75 9 with with IN cord-334550-xb0alubj 75 10 their -PRON- PRP$ cord-334550-xb0alubj 75 11 order order NN cord-334550-xb0alubj 75 12 of of IN cord-334550-xb0alubj 75 13 evolution evolution NN cord-334550-xb0alubj 75 14 and and CC cord-334550-xb0alubj 76 1 the the DT cord-334550-xb0alubj 76 2 defining define VBG cord-334550-xb0alubj 76 3 mutation(s mutation(s NNP cord-334550-xb0alubj 76 4 ) ) -RRB- cord-334550-xb0alubj 76 5 ( ( -LRB- cord-334550-xb0alubj 76 6 Biswas Biswas NNP cord-334550-xb0alubj 76 7 and and CC cord-334550-xb0alubj 76 8 Majumder Majumder NNP cord-334550-xb0alubj 76 9 , , , cord-334550-xb0alubj 76 10 2020 2020 CD cord-334550-xb0alubj 76 11 ) ) -RRB- cord-334550-xb0alubj 76 12 . . . cord-334550-xb0alubj 77 1 Defining define VBG cord-334550-xb0alubj 77 2 mutation(s mutation(s NNP cord-334550-xb0alubj 77 3 ) ) -RRB- cord-334550-xb0alubj 77 4 Phylogenetic phylogenetic JJ cord-334550-xb0alubj 77 5 analysis analysis NN cord-334550-xb0alubj 77 6 of of IN cord-334550-xb0alubj 77 7 SARS SARS NNP cord-334550-xb0alubj 77 8 - - HYPH cord-334550-xb0alubj 77 9 CoV-2 CoV-2 NNP cord-334550-xb0alubj 77 10 genomes genome NNS cord-334550-xb0alubj 77 11 demonstrated demonstrate VBD cord-334550-xb0alubj 77 12 two two CD cord-334550-xb0alubj 77 13 major major JJ cord-334550-xb0alubj 77 14 lineages lineage NNS cord-334550-xb0alubj 77 15 , , , cord-334550-xb0alubj 77 16 L L NNP cord-334550-xb0alubj 77 17 ( ( -LRB- cord-334550-xb0alubj 77 18 leucine leucine NNP cord-334550-xb0alubj 77 19 ) ) -RRB- cord-334550-xb0alubj 77 20 and and CC cord-334550-xb0alubj 77 21 S S NNP cord-334550-xb0alubj 77 22 ( ( -LRB- cord-334550-xb0alubj 77 23 serine serine NN cord-334550-xb0alubj 77 24 ) ) -RRB- cord-334550-xb0alubj 77 25 , , , cord-334550-xb0alubj 77 26 based base VBN cord-334550-xb0alubj 77 27 on on IN cord-334550-xb0alubj 77 28 single single JJ cord-334550-xb0alubj 77 29 nucleotide nucleotide JJ cord-334550-xb0alubj 77 30 polymorphisms polymorphism NNS cord-334550-xb0alubj 77 31 ( ( -LRB- cord-334550-xb0alubj 77 32 SNPs SNPs NNP cord-334550-xb0alubj 77 33 ) ) -RRB- cord-334550-xb0alubj 77 34 at at IN cord-334550-xb0alubj 77 35 positions position NNS cord-334550-xb0alubj 77 36 8,782 8,782 CD cord-334550-xb0alubj 77 37 ( ( -LRB- cord-334550-xb0alubj 77 38 orf1ab orf1ab NN cord-334550-xb0alubj 77 39 : : : cord-334550-xb0alubj 77 40 T8517C T8517C NNP cord-334550-xb0alubj 77 41 ) ) -RRB- cord-334550-xb0alubj 77 42 and and CC cord-334550-xb0alubj 77 43 28,144 28,144 CD cord-334550-xb0alubj 77 44 ( ( -LRB- cord-334550-xb0alubj 77 45 ORF8 ORF8 NNP cord-334550-xb0alubj 77 46 : : : cord-334550-xb0alubj 78 1 C251 C251 NNP cord-334550-xb0alubj 78 2 T T NNP cord-334550-xb0alubj 78 3 , , , cord-334550-xb0alubj 78 4 S84L S84L NNP cord-334550-xb0alubj 78 5 ) ) -RRB- cord-334550-xb0alubj 78 6 . . . cord-334550-xb0alubj 79 1 The the DT cord-334550-xb0alubj 79 2 L L NNP cord-334550-xb0alubj 79 3 lineage lineage NN cord-334550-xb0alubj 79 4 carries carry VBZ cord-334550-xb0alubj 79 5 a a DT cord-334550-xb0alubj 79 6 significantly significantly RB cord-334550-xb0alubj 79 7 higher high JJR cord-334550-xb0alubj 79 8 number number NN cord-334550-xb0alubj 79 9 of of IN cord-334550-xb0alubj 79 10 derived derive VBN cord-334550-xb0alubj 79 11 mutations mutation NNS cord-334550-xb0alubj 79 12 than than IN cord-334550-xb0alubj 79 13 S S NNP cord-334550-xb0alubj 79 14 lineage lineage NN cord-334550-xb0alubj 79 15 , , , cord-334550-xb0alubj 79 16 indicating indicate VBG cord-334550-xb0alubj 79 17 that that IN cord-334550-xb0alubj 79 18 these these DT cord-334550-xb0alubj 79 19 two two CD cord-334550-xb0alubj 79 20 lineages lineage NNS cord-334550-xb0alubj 79 21 might may MD cord-334550-xb0alubj 79 22 have have VB cord-334550-xb0alubj 79 23 different different JJ cord-334550-xb0alubj 79 24 rates rate NNS cord-334550-xb0alubj 79 25 of of IN cord-334550-xb0alubj 79 26 transmission transmission NN cord-334550-xb0alubj 79 27 and and CC cord-334550-xb0alubj 79 28 replication replication NN cord-334550-xb0alubj 79 29 . . . cord-334550-xb0alubj 80 1 Also also RB cord-334550-xb0alubj 80 2 , , , cord-334550-xb0alubj 80 3 the the DT cord-334550-xb0alubj 80 4 L L NNP cord-334550-xb0alubj 80 5 lineage lineage NN cord-334550-xb0alubj 80 6 has have VBZ cord-334550-xb0alubj 80 7 been be VBN cord-334550-xb0alubj 80 8 described describe VBN cord-334550-xb0alubj 80 9 to to TO cord-334550-xb0alubj 80 10 be be VB cord-334550-xb0alubj 80 11 more more RBR cord-334550-xb0alubj 80 12 aggressive aggressive JJ cord-334550-xb0alubj 80 13 and and CC cord-334550-xb0alubj 80 14 contagious contagious JJ cord-334550-xb0alubj 80 15 than than IN cord-334550-xb0alubj 80 16 S S NNP cord-334550-xb0alubj 80 17 lineage lineage NN cord-334550-xb0alubj 80 18 . . . cord-334550-xb0alubj 81 1 In in IN cord-334550-xb0alubj 81 2 India India NNP cord-334550-xb0alubj 81 3 , , , cord-334550-xb0alubj 81 4 the the DT cord-334550-xb0alubj 81 5 L L NNP cord-334550-xb0alubj 81 6 lineage lineage NN cord-334550-xb0alubj 81 7 is be VBZ cord-334550-xb0alubj 81 8 more more RBR cord-334550-xb0alubj 81 9 prevalent prevalent JJ cord-334550-xb0alubj 81 10 ( ( -LRB- cord-334550-xb0alubj 81 11 95.7 95.7 CD cord-334550-xb0alubj 81 12 % % NN cord-334550-xb0alubj 81 13 ) ) -RRB- cord-334550-xb0alubj 81 14 than than IN cord-334550-xb0alubj 81 15 S S NNP cord-334550-xb0alubj 81 16 lineage lineage NN cord-334550-xb0alubj 81 17 ( ( -LRB- cord-334550-xb0alubj 81 18 4.3 4.3 CD cord-334550-xb0alubj 81 19 % % NN cord-334550-xb0alubj 81 20 ) ) -RRB- cord-334550-xb0alubj 82 1 ( ( -LRB- cord-334550-xb0alubj 82 2 Banerjee Banerjee NNP cord-334550-xb0alubj 82 3 et et NNP cord-334550-xb0alubj 82 4 al al NNP cord-334550-xb0alubj 82 5 . . NNP cord-334550-xb0alubj 82 6 , , , cord-334550-xb0alubj 82 7 2020 2020 CD cord-334550-xb0alubj 82 8 ) ) -RRB- cord-334550-xb0alubj 82 9 , , , cord-334550-xb0alubj 82 10 with with IN cord-334550-xb0alubj 82 11 reports report NNS cord-334550-xb0alubj 82 12 claiming claim VBG cord-334550-xb0alubj 82 13 higher high JJR cord-334550-xb0alubj 82 14 fatality fatality NN cord-334550-xb0alubj 82 15 rates rate NNS cord-334550-xb0alubj 82 16 at at IN cord-334550-xb0alubj 82 17 places place NNS cord-334550-xb0alubj 82 18 where where WRB cord-334550-xb0alubj 82 19 the the DT cord-334550-xb0alubj 82 20 L L NNP cord-334550-xb0alubj 82 21 type type NN cord-334550-xb0alubj 82 22 is be VBZ cord-334550-xb0alubj 82 23 dominant dominant JJ cord-334550-xb0alubj 82 24 as as IN cord-334550-xb0alubj 82 25 in in IN cord-334550-xb0alubj 82 26 the the DT cord-334550-xb0alubj 82 27 Indian indian JJ cord-334550-xb0alubj 82 28 state state NN cord-334550-xb0alubj 82 29 of of IN cord-334550-xb0alubj 82 30 Gujarat Gujarat NNP cord-334550-xb0alubj 82 31 ( ( -LRB- cord-334550-xb0alubj 82 32 CFR CFR NNP cord-334550-xb0alubj 82 33 = = SYM cord-334550-xb0alubj 82 34 5.4 5.4 CD cord-334550-xb0alubj 82 35 % % NN cord-334550-xb0alubj 82 36 , , , cord-334550-xb0alubj 82 37 the the DT cord-334550-xb0alubj 82 38 highest high JJS cord-334550-xb0alubj 82 39 in in IN cord-334550-xb0alubj 82 40 India India NNP cord-334550-xb0alubj 82 41 ) ) -RRB- cord-334550-xb0alubj 82 42 . . . cord-334550-xb0alubj 83 1 5,6 5,6 CD cord-334550-xb0alubj 84 1 These these DT cord-334550-xb0alubj 84 2 observations observation NNS cord-334550-xb0alubj 84 3 indicate indicate VBP cord-334550-xb0alubj 84 4 that that DT cord-334550-xb0alubj 84 5 strain strain NN cord-334550-xb0alubj 84 6 difference difference NN cord-334550-xb0alubj 84 7 has have VBZ cord-334550-xb0alubj 84 8 some some DT cord-334550-xb0alubj 84 9 impact impact NN cord-334550-xb0alubj 84 10 on on IN cord-334550-xb0alubj 84 11 virulence virulence NN cord-334550-xb0alubj 84 12 and and CC cord-334550-xb0alubj 84 13 pathogenesis pathogenesis NN cord-334550-xb0alubj 84 14 . . . cord-334550-xb0alubj 85 1 Scientists scientist NNS cord-334550-xb0alubj 85 2 from from IN cord-334550-xb0alubj 85 3 the the DT cord-334550-xb0alubj 85 4 National National NNP cord-334550-xb0alubj 85 5 Institute Institute NNP cord-334550-xb0alubj 85 6 of of IN cord-334550-xb0alubj 85 7 Biomedical Biomedical NNP cord-334550-xb0alubj 85 8 Genomics Genomics NNP cord-334550-xb0alubj 85 9 , , , cord-334550-xb0alubj 85 10 India India NNP cord-334550-xb0alubj 85 11 , , , cord-334550-xb0alubj 85 12 performed perform VBN cord-334550-xb0alubj 85 13 phylodynamic phylodynamic JJ cord-334550-xb0alubj 85 14 analyses analysis NNS cord-334550-xb0alubj 85 15 and and CC cord-334550-xb0alubj 85 16 examined examine VBD cord-334550-xb0alubj 85 17 the the DT cord-334550-xb0alubj 85 18 temporal temporal JJ cord-334550-xb0alubj 85 19 and and CC cord-334550-xb0alubj 85 20 spatial spatial JJ cord-334550-xb0alubj 85 21 evolution evolution NN cord-334550-xb0alubj 85 22 of of IN cord-334550-xb0alubj 85 23 the the DT cord-334550-xb0alubj 85 24 virus virus NN cord-334550-xb0alubj 85 25 in in IN cord-334550-xb0alubj 85 26 3636 3636 CD cord-334550-xb0alubj 85 27 SAR SAR NNP cord-334550-xb0alubj 85 28 - - HYPH cord-334550-xb0alubj 85 29 CoV-2 CoV-2 NNP cord-334550-xb0alubj 85 30 sequences sequence NNS cord-334550-xb0alubj 85 31 deposited deposit VBN cord-334550-xb0alubj 85 32 in in IN cord-334550-xb0alubj 85 33 Global Global NNP cord-334550-xb0alubj 85 34 Initiative Initiative NNP cord-334550-xb0alubj 85 35 on on IN cord-334550-xb0alubj 85 36 Sharing Sharing NNP cord-334550-xb0alubj 85 37 All all DT cord-334550-xb0alubj 85 38 Influenza Influenza NNP cord-334550-xb0alubj 85 39 Data Data NNP cord-334550-xb0alubj 85 40 ( ( -LRB- cord-334550-xb0alubj 85 41 GISAID GISAID NNP cord-334550-xb0alubj 85 42 ) ) -RRB- cord-334550-xb0alubj 85 43 from from IN cord-334550-xb0alubj 85 44 55 55 CD cord-334550-xb0alubj 85 45 countries country NNS cord-334550-xb0alubj 85 46 and and CC cord-334550-xb0alubj 85 47 observed observe VBD cord-334550-xb0alubj 85 48 that that IN cord-334550-xb0alubj 85 49 at at RB cord-334550-xb0alubj 85 50 least least JJS cord-334550-xb0alubj 85 51 10 10 CD cord-334550-xb0alubj 85 52 distinct distinct JJ cord-334550-xb0alubj 85 53 clades clade NNS cord-334550-xb0alubj 85 54 ( ( -LRB- cord-334550-xb0alubj 85 55 A1a A1a NNP cord-334550-xb0alubj 85 56 , , , cord-334550-xb0alubj 85 57 A2 A2 NNP cord-334550-xb0alubj 85 58 , , , cord-334550-xb0alubj 85 59 A2a A2a NNP cord-334550-xb0alubj 85 60 , , , cord-334550-xb0alubj 85 61 A3 A3 NNP cord-334550-xb0alubj 85 62 , , , cord-334550-xb0alubj 85 63 A6 A6 NNP cord-334550-xb0alubj 85 64 , , , cord-334550-xb0alubj 85 65 A7 A7 NNP cord-334550-xb0alubj 85 66 , , , cord-334550-xb0alubj 85 67 B B NNP cord-334550-xb0alubj 85 68 , , , cord-334550-xb0alubj 85 69 B1 b1 NN cord-334550-xb0alubj 85 70 , , , cord-334550-xb0alubj 85 71 B2 b2 NN cord-334550-xb0alubj 85 72 , , , cord-334550-xb0alubj 85 73 and and CC cord-334550-xb0alubj 85 74 B4 B4 NNP cord-334550-xb0alubj 85 75 ) ) -RRB- cord-334550-xb0alubj 85 76 of of IN cord-334550-xb0alubj 85 77 the the DT cord-334550-xb0alubj 85 78 virus virus NN cord-334550-xb0alubj 85 79 have have VBP cord-334550-xb0alubj 85 80 originated originate VBN cord-334550-xb0alubj 85 81 from from IN cord-334550-xb0alubj 85 82 the the DT cord-334550-xb0alubj 85 83 ancestral ancestral JJ cord-334550-xb0alubj 85 84 clade clade NN cord-334550-xb0alubj 85 85 O o NN cord-334550-xb0alubj 85 86 ( ( -LRB- cord-334550-xb0alubj 85 87 Table table NN cord-334550-xb0alubj 85 88 1 1 CD cord-334550-xb0alubj 85 89 ) ) -RRB- cord-334550-xb0alubj 85 90 . . . cord-334550-xb0alubj 86 1 Though though IN cord-334550-xb0alubj 86 2 initially initially RB cord-334550-xb0alubj 86 3 , , , cord-334550-xb0alubj 86 4 the the DT cord-334550-xb0alubj 86 5 ancestral ancestral JJ cord-334550-xb0alubj 86 6 type type NN cord-334550-xb0alubj 86 7 was be VBD cord-334550-xb0alubj 86 8 most most RBS cord-334550-xb0alubj 86 9 frequent frequent JJ cord-334550-xb0alubj 86 10 in in IN cord-334550-xb0alubj 86 11 all all DT cord-334550-xb0alubj 86 12 countries country NNS cord-334550-xb0alubj 86 13 due due JJ cord-334550-xb0alubj 86 14 to to IN cord-334550-xb0alubj 86 15 return return NN cord-334550-xb0alubj 86 16 of of IN cord-334550-xb0alubj 86 17 travelers traveler NNS cord-334550-xb0alubj 86 18 from from IN cord-334550-xb0alubj 86 19 China China NNP cord-334550-xb0alubj 86 20 , , , cord-334550-xb0alubj 86 21 it -PRON- PRP cord-334550-xb0alubj 86 22 has have VBZ cord-334550-xb0alubj 86 23 gradually gradually RB cord-334550-xb0alubj 86 24 been be VBN cord-334550-xb0alubj 86 25 replaced replace VBN cord-334550-xb0alubj 86 26 by by IN cord-334550-xb0alubj 86 27 other other JJ cord-334550-xb0alubj 86 28 types type NNS cord-334550-xb0alubj 86 29 with with IN cord-334550-xb0alubj 86 30 clade clade NN cord-334550-xb0alubj 86 31 A2a A2a . cord-334550-xb0alubj 87 1 ( ( -LRB- cord-334550-xb0alubj 87 2 having have VBG cord-334550-xb0alubj 87 3 non non JJ cord-334550-xb0alubj 87 4 - - JJ cord-334550-xb0alubj 87 5 synonymous synonymous JJ cord-334550-xb0alubj 87 6 D614 d614 FW cord-334550-xb0alubj 87 7 G g NN cord-334550-xb0alubj 87 8 mutation mutation NN cord-334550-xb0alubj 87 9 in in IN cord-334550-xb0alubj 87 10 the the DT cord-334550-xb0alubj 87 11 S1 S1 NNP cord-334550-xb0alubj 87 12 / / SYM cord-334550-xb0alubj 87 13 S2 S2 NNP cord-334550-xb0alubj 87 14 furin furin NN cord-334550-xb0alubj 87 15 cleavage cleavage NN cord-334550-xb0alubj 87 16 site site NN cord-334550-xb0alubj 87 17 of of IN cord-334550-xb0alubj 87 18 S S NNP cord-334550-xb0alubj 87 19 protein protein NN cord-334550-xb0alubj 87 20 ) ) -RRB- cord-334550-xb0alubj 87 21 being be VBG cord-334550-xb0alubj 87 22 the the DT cord-334550-xb0alubj 87 23 most most RBS cord-334550-xb0alubj 87 24 dominant dominant JJ cord-334550-xb0alubj 87 25 type type NN cord-334550-xb0alubj 87 26 in in IN cord-334550-xb0alubj 87 27 India India NNP cord-334550-xb0alubj 87 28 and and CC cord-334550-xb0alubj 87 29 also also RB cord-334550-xb0alubj 87 30 , , , cord-334550-xb0alubj 87 31 globally globally RB cord-334550-xb0alubj 88 1 ( ( -LRB- cord-334550-xb0alubj 88 2 Biswas Biswas NNP cord-334550-xb0alubj 88 3 and and CC cord-334550-xb0alubj 88 4 Majumder Majumder NNP cord-334550-xb0alubj 88 5 , , , cord-334550-xb0alubj 88 6 2020 2020 CD cord-334550-xb0alubj 88 7 ) ) -RRB- cord-334550-xb0alubj 88 8 . . . cord-334550-xb0alubj 89 1 Phylogenetic phylogenetic JJ cord-334550-xb0alubj 89 2 analysis analysis NN cord-334550-xb0alubj 89 3 has have VBZ cord-334550-xb0alubj 89 4 revealed reveal VBN cord-334550-xb0alubj 89 5 significant significant JJ cord-334550-xb0alubj 89 6 regional regional JJ cord-334550-xb0alubj 89 7 variation variation NN cord-334550-xb0alubj 89 8 in in IN cord-334550-xb0alubj 89 9 frequencies frequency NNS cord-334550-xb0alubj 89 10 of of IN cord-334550-xb0alubj 89 11 different different JJ cord-334550-xb0alubj 89 12 clades clade NNS cord-334550-xb0alubj 89 13 across across IN cord-334550-xb0alubj 89 14 countries country NNS cord-334550-xb0alubj 89 15 . . . cord-334550-xb0alubj 90 1 For for IN cord-334550-xb0alubj 90 2 example example NN cord-334550-xb0alubj 90 3 , , , cord-334550-xb0alubj 90 4 in in IN cord-334550-xb0alubj 90 5 the the DT cord-334550-xb0alubj 90 6 United United NNP cord-334550-xb0alubj 90 7 States States NNP cord-334550-xb0alubj 90 8 , , , cord-334550-xb0alubj 90 9 clade clade NN cord-334550-xb0alubj 90 10 B1 b1 NN cord-334550-xb0alubj 90 11 is be VBZ cord-334550-xb0alubj 90 12 predominant predominant JJ cord-334550-xb0alubj 90 13 in in IN cord-334550-xb0alubj 90 14 Washington Washington NNP cord-334550-xb0alubj 90 15 D.C. D.C. NNP cord-334550-xb0alubj 90 16 and and CC cord-334550-xb0alubj 90 17 West West NNP cord-334550-xb0alubj 90 18 Coast Coast NNP cord-334550-xb0alubj 90 19 , , , cord-334550-xb0alubj 90 20 while while IN cord-334550-xb0alubj 90 21 in in IN cord-334550-xb0alubj 90 22 New New NNP cord-334550-xb0alubj 90 23 York York NNP cord-334550-xb0alubj 90 24 and and CC cord-334550-xb0alubj 90 25 East East NNP cord-334550-xb0alubj 90 26 Coast Coast NNP cord-334550-xb0alubj 90 27 , , , cord-334550-xb0alubj 90 28 clade clade NN cord-334550-xb0alubj 90 29 A2a a2a NN cord-334550-xb0alubj 90 30 is be VBZ cord-334550-xb0alubj 90 31 the the DT cord-334550-xb0alubj 90 32 modal modal JJ cord-334550-xb0alubj 90 33 type type NN cord-334550-xb0alubj 90 34 ( ( -LRB- cord-334550-xb0alubj 90 35 Biswas Biswas NNP cord-334550-xb0alubj 90 36 and and CC cord-334550-xb0alubj 90 37 Majumder Majumder NNP cord-334550-xb0alubj 90 38 , , , cord-334550-xb0alubj 90 39 2020 2020 CD cord-334550-xb0alubj 90 40 ; ; : cord-334550-xb0alubj 90 41 Brufsky Brufsky NNP cord-334550-xb0alubj 90 42 , , , cord-334550-xb0alubj 90 43 2020 2020 CD cord-334550-xb0alubj 90 44 ) ) -RRB- cord-334550-xb0alubj 90 45 . . . cord-334550-xb0alubj 91 1 An an DT cord-334550-xb0alubj 91 2 analysis analysis NN cord-334550-xb0alubj 91 3 of of IN cord-334550-xb0alubj 91 4 35 35 CD cord-334550-xb0alubj 91 5 viral viral JJ cord-334550-xb0alubj 91 6 sequences sequence NNS cord-334550-xb0alubj 91 7 submitted submit VBN cord-334550-xb0alubj 91 8 to to IN cord-334550-xb0alubj 91 9 GISAID GISAID NNP cord-334550-xb0alubj 91 10 from from IN cord-334550-xb0alubj 91 11 India India NNP cord-334550-xb0alubj 91 12 revealed reveal VBD cord-334550-xb0alubj 91 13 the the DT cord-334550-xb0alubj 91 14 existence existence NN cord-334550-xb0alubj 91 15 of of IN cord-334550-xb0alubj 91 16 four four CD cord-334550-xb0alubj 91 17 clades clade NNS cord-334550-xb0alubj 91 18 : : : cord-334550-xb0alubj 91 19 ancestral ancestral JJ cord-334550-xb0alubj 91 20 clade clade NN cord-334550-xb0alubj 91 21 O o NN cord-334550-xb0alubj 91 22 ( ( -LRB- cord-334550-xb0alubj 91 23 14.3 14.3 CD cord-334550-xb0alubj 91 24 % % NN cord-334550-xb0alubj 91 25 ) ) -RRB- cord-334550-xb0alubj 91 26 and and CC cord-334550-xb0alubj 91 27 derived derive VBN cord-334550-xb0alubj 91 28 clades clade NNS cord-334550-xb0alubj 92 1 A2a a2a NN cord-334550-xb0alubj 92 2 ( ( -LRB- cord-334550-xb0alubj 92 3 45.7 45.7 CD cord-334550-xb0alubj 92 4 % % NN cord-334550-xb0alubj 92 5 ) ) -RRB- cord-334550-xb0alubj 92 6 , , , cord-334550-xb0alubj 92 7 A3 A3 NNP cord-334550-xb0alubj 92 8 ( ( -LRB- cord-334550-xb0alubj 92 9 37.1 37.1 CD cord-334550-xb0alubj 92 10 % % NN cord-334550-xb0alubj 92 11 ) ) -RRB- cord-334550-xb0alubj 92 12 , , , cord-334550-xb0alubj 92 13 and and CC cord-334550-xb0alubj 92 14 B b NN cord-334550-xb0alubj 92 15 ( ( -LRB- cord-334550-xb0alubj 92 16 2.9 2.9 CD cord-334550-xb0alubj 92 17 % % NN cord-334550-xb0alubj 92 18 ) ) -RRB- cord-334550-xb0alubj 92 19 . . . cord-334550-xb0alubj 93 1 All all DT cord-334550-xb0alubj 93 2 individuals individual NNS cord-334550-xb0alubj 93 3 5 5 CD cord-334550-xb0alubj 93 4 Available available JJ cord-334550-xb0alubj 93 5 from from IN cord-334550-xb0alubj 93 6 : : : cord-334550-xb0alubj 93 7 https://www.indiatoday.in/india/story/wuhan-s-l-strainmay-be-behind-gujarat-s-high-death-rate-experts-1671346-2020-04-26 https://www.indiatoday.in/india/story/wuhan-s-l-strainmay-be-behind-gujarat-s-high-death-rate-experts-1671346-2020-04-26 NNP cord-334550-xb0alubj 94 1 ( ( -LRB- cord-334550-xb0alubj 94 2 Accessed Accessed NNP cord-334550-xb0alubj 94 3 May May NNP cord-334550-xb0alubj 94 4 25 25 CD cord-334550-xb0alubj 94 5 , , , cord-334550-xb0alubj 94 6 2020 2020 CD cord-334550-xb0alubj 94 7 ) ) -RRB- cord-334550-xb0alubj 94 8 . . . cord-334550-xb0alubj 95 1 6 6 CD cord-334550-xb0alubj 96 1 Available available JJ cord-334550-xb0alubj 96 2 from from IN cord-334550-xb0alubj 96 3 : : : cord-334550-xb0alubj 96 4 https://www.mohfw.gov.in/ https://www.mohfw.gov.in/ NN cord-334550-xb0alubj 97 1 ( ( -LRB- cord-334550-xb0alubj 97 2 Accessed access VBN cord-334550-xb0alubj 97 3 July July NNP cord-334550-xb0alubj 97 4 03 03 CD cord-334550-xb0alubj 97 5 , , , cord-334550-xb0alubj 97 6 2020 2020 CD cord-334550-xb0alubj 97 7 ) ) -RRB- cord-334550-xb0alubj 97 8 . . . cord-334550-xb0alubj 98 1 infected infect VBN cord-334550-xb0alubj 98 2 with with IN cord-334550-xb0alubj 98 3 A3 A3 NNP cord-334550-xb0alubj 98 4 had have VBD cord-334550-xb0alubj 98 5 travel travel NN cord-334550-xb0alubj 98 6 history history NN cord-334550-xb0alubj 98 7 to to IN cord-334550-xb0alubj 98 8 Iran Iran NNP cord-334550-xb0alubj 98 9 , , , cord-334550-xb0alubj 98 10 while while IN cord-334550-xb0alubj 98 11 those those DT cord-334550-xb0alubj 98 12 with with IN cord-334550-xb0alubj 98 13 A2a A2a NNP cord-334550-xb0alubj 98 14 had have VBD cord-334550-xb0alubj 98 15 no no DT cord-334550-xb0alubj 98 16 history history NN cord-334550-xb0alubj 98 17 of of IN cord-334550-xb0alubj 98 18 international international JJ cord-334550-xb0alubj 98 19 travel travel NN cord-334550-xb0alubj 98 20 . . . cord-334550-xb0alubj 99 1 Thus thus RB cord-334550-xb0alubj 99 2 , , , cord-334550-xb0alubj 99 3 a a DT cord-334550-xb0alubj 99 4 temporal temporal JJ cord-334550-xb0alubj 99 5 decline decline NN cord-334550-xb0alubj 99 6 in in IN cord-334550-xb0alubj 99 7 the the DT cord-334550-xb0alubj 99 8 diversity diversity NN cord-334550-xb0alubj 99 9 of of IN cord-334550-xb0alubj 99 10 SARS SARS NNP cord-334550-xb0alubj 99 11 - - HYPH cord-334550-xb0alubj 99 12 CoV-2 CoV-2 NNP cord-334550-xb0alubj 99 13 clades clade NNS cord-334550-xb0alubj 99 14 has have VBZ cord-334550-xb0alubj 99 15 been be VBN cord-334550-xb0alubj 99 16 observed observe VBN cord-334550-xb0alubj 99 17 globally globally RB cord-334550-xb0alubj 99 18 , , , cord-334550-xb0alubj 99 19 which which WDT cord-334550-xb0alubj 99 20 may may MD cord-334550-xb0alubj 99 21 affect affect VB cord-334550-xb0alubj 99 22 transmission transmission NN cord-334550-xb0alubj 99 23 and and CC cord-334550-xb0alubj 99 24 pathogenicity pathogenicity NN cord-334550-xb0alubj 99 25 . . . cord-334550-xb0alubj 100 1 A a DT cord-334550-xb0alubj 100 2 mutational mutational JJ cord-334550-xb0alubj 100 3 analysis analysis NN cord-334550-xb0alubj 100 4 showed show VBD cord-334550-xb0alubj 100 5 co co NN cord-334550-xb0alubj 100 6 - - NN cord-334550-xb0alubj 100 7 circulation circulation NN cord-334550-xb0alubj 100 8 of of IN cord-334550-xb0alubj 100 9 two two CD cord-334550-xb0alubj 100 10 groups group NNS cord-334550-xb0alubj 100 11 ( ( -LRB- cord-334550-xb0alubj 100 12 major major JJ cord-334550-xb0alubj 100 13 and and CC cord-334550-xb0alubj 100 14 minor minor JJ cord-334550-xb0alubj 100 15 ) ) -RRB- cord-334550-xb0alubj 100 16 of of IN cord-334550-xb0alubj 100 17 the the DT cord-334550-xb0alubj 100 18 mutated mutate VBN cord-334550-xb0alubj 100 19 virus virus NN cord-334550-xb0alubj 100 20 in in IN cord-334550-xb0alubj 100 21 India India NNP cord-334550-xb0alubj 100 22 . . . cord-334550-xb0alubj 101 1 The the DT cord-334550-xb0alubj 101 2 " " `` cord-334550-xb0alubj 101 3 major major JJ cord-334550-xb0alubj 101 4 group group NN cord-334550-xb0alubj 101 5 " " '' cord-334550-xb0alubj 101 6 ( ( -LRB- cord-334550-xb0alubj 101 7 52.2 52.2 CD cord-334550-xb0alubj 101 8 % % NN cord-334550-xb0alubj 101 9 ) ) -RRB- cord-334550-xb0alubj 101 10 represents represent VBZ cord-334550-xb0alubj 101 11 A2a A2a NNP cord-334550-xb0alubj 101 12 clade clade NN cord-334550-xb0alubj 101 13 that that WDT cord-334550-xb0alubj 101 14 harbors harbor VBZ cord-334550-xb0alubj 101 15 four four CD cord-334550-xb0alubj 101 16 co co JJ cord-334550-xb0alubj 101 17 - - JJ cord-334550-xb0alubj 101 18 existing existing JJ cord-334550-xb0alubj 101 19 SNPs snp NNS cord-334550-xb0alubj 101 20 : : : cord-334550-xb0alubj 102 1 241C 241c CD cord-334550-xb0alubj 103 1 > > XX cord-334550-xb0alubj 104 1 T T NNP cord-334550-xb0alubj 104 2 ( ( -LRB- cord-334550-xb0alubj 104 3 5 5 CD cord-334550-xb0alubj 104 4 UTR UTR NNP cord-334550-xb0alubj 104 5 ) ) -RRB- cord-334550-xb0alubj 104 6 , , , cord-334550-xb0alubj 104 7 3037C 3037C NNP cord-334550-xb0alubj 104 8 > > XX cord-334550-xb0alubj 104 9 T T NNP cord-334550-xb0alubj 104 10 ( ( -LRB- cord-334550-xb0alubj 104 11 F106F f106f XX cord-334550-xb0alubj 104 12 , , , cord-334550-xb0alubj 104 13 NSP3 NSP3 NNP cord-334550-xb0alubj 104 14 ) ) -RRB- cord-334550-xb0alubj 104 15 , , , cord-334550-xb0alubj 104 16 14403C 14403c CD cord-334550-xb0alubj 105 1 > > XX cord-334550-xb0alubj 106 1 T T NNP cord-334550-xb0alubj 106 2 ( ( -LRB- cord-334550-xb0alubj 106 3 P323L P323L NNP cord-334550-xb0alubj 106 4 , , , cord-334550-xb0alubj 106 5 RdRP RdRP NNP cord-334550-xb0alubj 106 6 / / SYM cord-334550-xb0alubj 106 7 NSP12 NSP12 NNP cord-334550-xb0alubj 106 8 ) ) -RRB- cord-334550-xb0alubj 106 9 and and CC cord-334550-xb0alubj 106 10 23403A 23403a CD cord-334550-xb0alubj 107 1 > > XX cord-334550-xb0alubj 108 1 G g NN cord-334550-xb0alubj 108 2 ( ( -LRB- cord-334550-xb0alubj 108 3 D614 d614 FW cord-334550-xb0alubj 108 4 G g NN cord-334550-xb0alubj 108 5 , , , cord-334550-xb0alubj 108 6 S S NNP cord-334550-xb0alubj 108 7 glycoprotein glycoprotein NN cord-334550-xb0alubj 108 8 ) ) -RRB- cord-334550-xb0alubj 108 9 . . . cord-334550-xb0alubj 109 1 The the DT cord-334550-xb0alubj 109 2 " " `` cord-334550-xb0alubj 109 3 minor minor JJ cord-334550-xb0alubj 109 4 group group NN cord-334550-xb0alubj 109 5 " " '' cord-334550-xb0alubj 109 6 ( ( -LRB- cord-334550-xb0alubj 109 7 30.4 30.4 CD cord-334550-xb0alubj 109 8 % % NN cord-334550-xb0alubj 109 9 ) ) -RRB- cord-334550-xb0alubj 109 10 consists consist VBZ cord-334550-xb0alubj 109 11 of of IN cord-334550-xb0alubj 109 12 strains strain NNS cord-334550-xb0alubj 109 13 showing show VBG cord-334550-xb0alubj 109 14 five five CD cord-334550-xb0alubj 109 15 distinct distinct JJ cord-334550-xb0alubj 109 16 mutations mutation NNS cord-334550-xb0alubj 109 17 : : : cord-334550-xb0alubj 110 1 13730C 13730c LS cord-334550-xb0alubj 110 2 > > XX cord-334550-xb0alubj 110 3 T t NN cord-334550-xb0alubj 110 4 ( ( -LRB- cord-334550-xb0alubj 110 5 A97V A97V NNP cord-334550-xb0alubj 110 6 , , , cord-334550-xb0alubj 110 7 RdRP RdRP NNP cord-334550-xb0alubj 110 8 / / SYM cord-334550-xb0alubj 110 9 NSP12 NSP12 NNP cord-334550-xb0alubj 110 10 ) ) -RRB- cord-334550-xb0alubj 110 11 , , , cord-334550-xb0alubj 110 12 23929C 23929c CD cord-334550-xb0alubj 111 1 > > XX cord-334550-xb0alubj 112 1 T T NNP cord-334550-xb0alubj 112 2 ( ( -LRB- cord-334550-xb0alubj 112 3 Y789Y y789y ADD cord-334550-xb0alubj 112 4 , , , cord-334550-xb0alubj 112 5 S S NNP cord-334550-xb0alubj 112 6 ) ) -RRB- cord-334550-xb0alubj 112 7 , , , cord-334550-xb0alubj 112 8 28311C 28311c CD cord-334550-xb0alubj 113 1 > > XX cord-334550-xb0alubj 114 1 T T NNP cord-334550-xb0alubj 114 2 ( ( -LRB- cord-334550-xb0alubj 114 3 P13L P13L NNP cord-334550-xb0alubj 114 4 , , , cord-334550-xb0alubj 114 5 N N NNP cord-334550-xb0alubj 114 6 ) ) -RRB- cord-334550-xb0alubj 114 7 , , , cord-334550-xb0alubj 114 8 6312C 6312C NNP cord-334550-xb0alubj 114 9 > > XX cord-334550-xb0alubj 115 1 A a DT cord-334550-xb0alubj 115 2 ( ( -LRB- cord-334550-xb0alubj 115 3 T1198 T1198 NNP cord-334550-xb0alubj 115 4 K K NNP cord-334550-xb0alubj 115 5 , , , cord-334550-xb0alubj 115 6 NSP3 NSP3 NNP cord-334550-xb0alubj 115 7 ) ) -RRB- cord-334550-xb0alubj 115 8 and and CC cord-334550-xb0alubj 115 9 11083 11083 CD cord-334550-xb0alubj 115 10 G g NN cord-334550-xb0alubj 116 1 > > XX cord-334550-xb0alubj 117 1 T T NNP cord-334550-xb0alubj 117 2 ( ( -LRB- cord-334550-xb0alubj 117 3 L37F L37F NNP cord-334550-xb0alubj 117 4 , , , cord-334550-xb0alubj 117 5 NSP6 NSP6 NNP cord-334550-xb0alubj 117 6 ) ) -RRB- cord-334550-xb0alubj 117 7 . . . cord-334550-xb0alubj 118 1 All all PDT cord-334550-xb0alubj 118 2 these these DT cord-334550-xb0alubj 118 3 mutations mutation NNS cord-334550-xb0alubj 118 4 , , , cord-334550-xb0alubj 118 5 except except IN cord-334550-xb0alubj 118 6 11083 11083 CD cord-334550-xb0alubj 118 7 G g NN cord-334550-xb0alubj 119 1 > > XX cord-334550-xb0alubj 120 1 T T NNP cord-334550-xb0alubj 120 2 ( ( -LRB- cord-334550-xb0alubj 120 3 L37F L37F NNP cord-334550-xb0alubj 120 4 , , , cord-334550-xb0alubj 120 5 NSP6 NSP6 NNP cord-334550-xb0alubj 120 6 ) ) -RRB- cord-334550-xb0alubj 120 7 are be VBP cord-334550-xb0alubj 120 8 unique unique JJ cord-334550-xb0alubj 120 9 to to IN cord-334550-xb0alubj 120 10 Indian indian JJ cord-334550-xb0alubj 120 11 SARS SARS NNP cord-334550-xb0alubj 120 12 - - HYPH cord-334550-xb0alubj 120 13 CoV-2 CoV-2 NNP cord-334550-xb0alubj 120 14 strains strain NNS cord-334550-xb0alubj 120 15 ( ( -LRB- cord-334550-xb0alubj 120 16 Guan Guan NNP cord-334550-xb0alubj 120 17 et et FW cord-334550-xb0alubj 120 18 al al NNP cord-334550-xb0alubj 120 19 . . NNP cord-334550-xb0alubj 120 20 , , , cord-334550-xb0alubj 120 21 2020 2020 CD cord-334550-xb0alubj 120 22 ; ; . cord-334550-xb0alubj 121 1 Mercatelli Mercatelli NNP cord-334550-xb0alubj 121 2 and and CC cord-334550-xb0alubj 121 3 Giorgi Giorgi NNP cord-334550-xb0alubj 121 4 , , , cord-334550-xb0alubj 121 5 2020 2020 CD cord-334550-xb0alubj 121 6 ; ; : cord-334550-xb0alubj 121 7 Wang Wang NNP cord-334550-xb0alubj 121 8 et et NNP cord-334550-xb0alubj 121 9 al al NNP cord-334550-xb0alubj 121 10 . . NNP cord-334550-xb0alubj 121 11 , , , cord-334550-xb0alubj 121 12 2020 2020 CD cord-334550-xb0alubj 121 13 ) ) -RRB- cord-334550-xb0alubj 121 14 . . . cord-334550-xb0alubj 122 1 Mutations mutation NNS cord-334550-xb0alubj 122 2 22374A 22374a CD cord-334550-xb0alubj 123 1 > > XX cord-334550-xb0alubj 123 2 G G NNP cord-334550-xb0alubj 123 3 ( ( -LRB- cord-334550-xb0alubj 123 4 Q271R Q271R NNP cord-334550-xb0alubj 123 5 ) ) -RRB- cord-334550-xb0alubj 123 6 , , , cord-334550-xb0alubj 123 7 245 245 CD cord-334550-xb0alubj 123 8 24933 24933 CD cord-334550-xb0alubj 123 9 G g NN cord-334550-xb0alubj 124 1 > > XX cord-334550-xb0alubj 125 1 T T NNP cord-334550-xb0alubj 125 2 ( ( -LRB- cord-334550-xb0alubj 125 3 G1124V G1124V NNP cord-334550-xb0alubj 125 4 ) ) -RRB- cord-334550-xb0alubj 125 5 and and CC cord-334550-xb0alubj 125 6 22444C 22444c CD cord-334550-xb0alubj 126 1 > > XX cord-334550-xb0alubj 127 1 T T NNP cord-334550-xb0alubj 127 2 ( ( -LRB- cord-334550-xb0alubj 127 3 D294D D294D NNP cord-334550-xb0alubj 127 4 ) ) -RRB- cord-334550-xb0alubj 127 5 in in IN cord-334550-xb0alubj 127 6 S S NNP cord-334550-xb0alubj 127 7 gene gene NN cord-334550-xb0alubj 127 8 and and CC cord-334550-xb0alubj 127 9 missense missense NN cord-334550-xb0alubj 127 10 mutations mutation NNS cord-334550-xb0alubj 127 11 Q271R Q271R NNP cord-334550-xb0alubj 127 12 and and CC cord-334550-xb0alubj 127 13 G1124V G1124V NNP cord-334550-xb0alubj 127 14 in in IN cord-334550-xb0alubj 127 15 S S NNP cord-334550-xb0alubj 127 16 protein protein NN cord-334550-xb0alubj 127 17 have have VBP cord-334550-xb0alubj 127 18 been be VBN cord-334550-xb0alubj 127 19 observed observe VBN cord-334550-xb0alubj 127 20 exclusively exclusively RB cord-334550-xb0alubj 127 21 in in IN cord-334550-xb0alubj 127 22 Indian indian JJ cord-334550-xb0alubj 127 23 strains strain NNS cord-334550-xb0alubj 127 24 , , , cord-334550-xb0alubj 127 25 which which WDT cord-334550-xb0alubj 127 26 might may MD cord-334550-xb0alubj 127 27 alter alter VB cord-334550-xb0alubj 127 28 the the DT cord-334550-xb0alubj 127 29 protein protein NN cord-334550-xb0alubj 127 30 function function NN cord-334550-xb0alubj 127 31 and and CC cord-334550-xb0alubj 127 32 thus thus RB cord-334550-xb0alubj 127 33 , , , cord-334550-xb0alubj 127 34 affect affect VBP cord-334550-xb0alubj 127 35 virulence virulence NN cord-334550-xb0alubj 127 36 and and CC cord-334550-xb0alubj 127 37 pathogenicity pathogenicity NN cord-334550-xb0alubj 127 38 ( ( -LRB- cord-334550-xb0alubj 127 39 Banerjee Banerjee NNP cord-334550-xb0alubj 127 40 et et NNP cord-334550-xb0alubj 127 41 al al NNP cord-334550-xb0alubj 127 42 . . NNP cord-334550-xb0alubj 127 43 , , , cord-334550-xb0alubj 127 44 2020 2020 CD cord-334550-xb0alubj 127 45 ) ) -RRB- cord-334550-xb0alubj 127 46 . . . cord-334550-xb0alubj 128 1 Researchers researcher NNS cord-334550-xb0alubj 128 2 from from IN cord-334550-xb0alubj 128 3 Translational Translational NNP cord-334550-xb0alubj 128 4 Bioinformatics Bioinformatics NNP cord-334550-xb0alubj 128 5 Group Group NNP cord-334550-xb0alubj 128 6 at at IN cord-334550-xb0alubj 128 7 International International NNP cord-334550-xb0alubj 128 8 Center Center NNP cord-334550-xb0alubj 128 9 for for IN cord-334550-xb0alubj 128 10 Genetic Genetic NNP cord-334550-xb0alubj 128 11 Engineering Engineering NNP cord-334550-xb0alubj 128 12 and and CC cord-334550-xb0alubj 128 13 Biotechnology Biotechnology NNP cord-334550-xb0alubj 128 14 ( ( -LRB- cord-334550-xb0alubj 128 15 ICGEB ICGEB NNP cord-334550-xb0alubj 128 16 ) ) -RRB- cord-334550-xb0alubj 128 17 in in IN cord-334550-xb0alubj 128 18 collaboration collaboration NN cord-334550-xb0alubj 128 19 with with IN cord-334550-xb0alubj 128 20 the the DT cord-334550-xb0alubj 128 21 Department Department NNP cord-334550-xb0alubj 128 22 of of IN cord-334550-xb0alubj 128 23 Biochemistry Biochemistry NNP cord-334550-xb0alubj 128 24 , , , cord-334550-xb0alubj 128 25 Jamia Jamia NNP cord-334550-xb0alubj 128 26 Hamdard Hamdard NNP cord-334550-xb0alubj 128 27 , , , cord-334550-xb0alubj 128 28 New New NNP cord-334550-xb0alubj 128 29 Delhi Delhi NNP cord-334550-xb0alubj 128 30 , , , cord-334550-xb0alubj 128 31 India India NNP cord-334550-xb0alubj 128 32 , , , cord-334550-xb0alubj 128 33 performed perform VBD cord-334550-xb0alubj 128 34 an an DT cord-334550-xb0alubj 128 35 integrated integrated JJ cord-334550-xb0alubj 128 36 mutational mutational JJ cord-334550-xb0alubj 128 37 analysis analysis NN cord-334550-xb0alubj 128 38 of of IN cord-334550-xb0alubj 128 39 SARS SARS NNP cord-334550-xb0alubj 128 40 - - HYPH cord-334550-xb0alubj 128 41 CoV-2 CoV-2 NNP cord-334550-xb0alubj 128 42 genomes genome NNS cord-334550-xb0alubj 128 43 from from IN cord-334550-xb0alubj 128 44 different different JJ cord-334550-xb0alubj 128 45 geographical geographical JJ cord-334550-xb0alubj 128 46 locations location NNS cord-334550-xb0alubj 128 47 , , , cord-334550-xb0alubj 128 48 including include VBG cord-334550-xb0alubj 128 49 India India NNP cord-334550-xb0alubj 128 50 , , , cord-334550-xb0alubj 128 51 Italy Italy NNP cord-334550-xb0alubj 128 52 , , , cord-334550-xb0alubj 128 53 United United NNP cord-334550-xb0alubj 128 54 States States NNP cord-334550-xb0alubj 128 55 , , , cord-334550-xb0alubj 128 56 Nepal Nepal NNP cord-334550-xb0alubj 128 57 and and CC cord-334550-xb0alubj 128 58 Wuhan Wuhan NNP cord-334550-xb0alubj 128 59 , , , cord-334550-xb0alubj 128 60 and and CC cord-334550-xb0alubj 128 61 observed observe VBD cord-334550-xb0alubj 128 62 a a DT cord-334550-xb0alubj 128 63 novel novel JJ cord-334550-xb0alubj 128 64 mutation mutation NN cord-334550-xb0alubj 128 65 in in IN cord-334550-xb0alubj 128 66 S s NN cord-334550-xb0alubj 128 67 protein protein NN cord-334550-xb0alubj 128 68 ( ( -LRB- cord-334550-xb0alubj 128 69 A930V A930V NNP cord-334550-xb0alubj 128 70 , , , cord-334550-xb0alubj 128 71 24351C 24351c CD cord-334550-xb0alubj 128 72 > > XX cord-334550-xb0alubj 128 73 T T NNP cord-334550-xb0alubj 128 74 ) ) -RRB- cord-334550-xb0alubj 128 75 of of IN cord-334550-xb0alubj 128 76 the the DT cord-334550-xb0alubj 128 77 Indian indian JJ cord-334550-xb0alubj 128 78 strain strain NN cord-334550-xb0alubj 128 79 , , , cord-334550-xb0alubj 128 80 which which WDT cord-334550-xb0alubj 128 81 was be VBD cord-334550-xb0alubj 128 82 absent absent JJ cord-334550-xb0alubj 128 83 in in IN cord-334550-xb0alubj 128 84 other other JJ cord-334550-xb0alubj 128 85 strains strain NNS cord-334550-xb0alubj 128 86 ( ( -LRB- cord-334550-xb0alubj 128 87 Sardar Sardar NNP cord-334550-xb0alubj 128 88 et et NNP cord-334550-xb0alubj 128 89 al al NNP cord-334550-xb0alubj 128 90 . . NNP cord-334550-xb0alubj 128 91 , , , cord-334550-xb0alubj 128 92 2020 2020 CD cord-334550-xb0alubj 128 93 ) ) -RRB- cord-334550-xb0alubj 128 94 . . . cord-334550-xb0alubj 129 1 A a DT cord-334550-xb0alubj 129 2 triple triple JJ cord-334550-xb0alubj 129 3 site site NN cord-334550-xb0alubj 129 4 mutation mutation NN cord-334550-xb0alubj 129 5 28881 28881 CD cord-334550-xb0alubj 129 6 - - SYM cord-334550-xb0alubj 129 7 28883 28883 CD cord-334550-xb0alubj 130 1 GGG GGG NNP cord-334550-xb0alubj 131 1 > > XX cord-334550-xb0alubj 132 1 AAC AAC NNP cord-334550-xb0alubj 132 2 has have VBZ cord-334550-xb0alubj 132 3 been be VBN cord-334550-xb0alubj 132 4 observed observe VBN cord-334550-xb0alubj 132 5 at at IN cord-334550-xb0alubj 132 6 203/204 203/204 CD cord-334550-xb0alubj 132 7 region region NN cord-334550-xb0alubj 132 8 of of IN cord-334550-xb0alubj 132 9 the the DT cord-334550-xb0alubj 132 10 N n CD cord-334550-xb0alubj 132 11 gene gene NN cord-334550-xb0alubj 132 12 that that WDT cord-334550-xb0alubj 132 13 might may MD cord-334550-xb0alubj 132 14 alter alter VB cord-334550-xb0alubj 132 15 the the DT cord-334550-xb0alubj 132 16 phosphorylation phosphorylation NN cord-334550-xb0alubj 132 17 of of IN cord-334550-xb0alubj 132 18 serine serine JJ cord-334550-xb0alubj 132 19 residue residue NN cord-334550-xb0alubj 132 20 of of IN cord-334550-xb0alubj 132 21 N n CD cord-334550-xb0alubj 132 22 protein protein NN cord-334550-xb0alubj 132 23 and and CC cord-334550-xb0alubj 132 24 interfere interfere VB cord-334550-xb0alubj 132 25 with with IN cord-334550-xb0alubj 132 26 its -PRON- PRP$ cord-334550-xb0alubj 132 27 function function NN cord-334550-xb0alubj 132 28 , , , cord-334550-xb0alubj 132 29 thus thus RB cord-334550-xb0alubj 132 30 reducing reduce VBG cord-334550-xb0alubj 132 31 the the DT cord-334550-xb0alubj 132 32 pathogenicity pathogenicity NN cord-334550-xb0alubj 132 33 of of IN cord-334550-xb0alubj 132 34 the the DT cord-334550-xb0alubj 132 35 strain strain NN cord-334550-xb0alubj 132 36 ( ( -LRB- cord-334550-xb0alubj 132 37 Ayub Ayub NNP cord-334550-xb0alubj 132 38 , , , cord-334550-xb0alubj 132 39 2020 2020 CD cord-334550-xb0alubj 132 40 ) ) -RRB- cord-334550-xb0alubj 132 41 . . . cord-334550-xb0alubj 133 1 Besides besides RB cord-334550-xb0alubj 133 2 , , , cord-334550-xb0alubj 133 3 some some DT cord-334550-xb0alubj 133 4 Indian indian JJ cord-334550-xb0alubj 133 5 strains strain NNS cord-334550-xb0alubj 133 6 have have VBP cord-334550-xb0alubj 133 7 displayed display VBN cord-334550-xb0alubj 133 8 unique unique JJ cord-334550-xb0alubj 133 9 mutations mutation NNS cord-334550-xb0alubj 133 10 in in IN cord-334550-xb0alubj 133 11 the the DT cord-334550-xb0alubj 133 12 NSP3 NSP3 NNP cord-334550-xb0alubj 133 13 gene gene NN cord-334550-xb0alubj 133 14 at at IN cord-334550-xb0alubj 133 15 positions position NNS cord-334550-xb0alubj 133 16 6310C 6310c CD cord-334550-xb0alubj 133 17 > > XX cord-334550-xb0alubj 134 1 A a DT cord-334550-xb0alubj 134 2 ( ( -LRB- cord-334550-xb0alubj 134 3 S1197R S1197R NNP cord-334550-xb0alubj 134 4 ) ) -RRB- cord-334550-xb0alubj 134 5 , , . cord-334550-xb0alubj 135 1 7392C 7392C NNP cord-334550-xb0alubj 135 2 > > XX cord-334550-xb0alubj 136 1 T T NNP cord-334550-xb0alubj 136 2 ( ( -LRB- cord-334550-xb0alubj 136 3 P1558L P1558L NNP cord-334550-xb0alubj 136 4 ) ) -RRB- cord-334550-xb0alubj 136 5 and and CC cord-334550-xb0alubj 136 6 6466A 6466A NNP cord-334550-xb0alubj 137 1 > > XX cord-334550-xb0alubj 138 1 G g NN cord-334550-xb0alubj 138 2 ( ( -LRB- cord-334550-xb0alubj 138 3 K1249 K1249 NNP cord-334550-xb0alubj 138 4 K K NNP cord-334550-xb0alubj 138 5 ) ) -RRB- cord-334550-xb0alubj 139 1 ( ( -LRB- cord-334550-xb0alubj 139 2 Banerjee Banerjee NNP cord-334550-xb0alubj 139 3 et et NNP cord-334550-xb0alubj 139 4 al al NNP cord-334550-xb0alubj 139 5 . . NNP cord-334550-xb0alubj 139 6 , , , cord-334550-xb0alubj 139 7 2020 2020 CD cord-334550-xb0alubj 139 8 ) ) -RRB- cord-334550-xb0alubj 139 9 . . . cord-334550-xb0alubj 140 1 The the DT cord-334550-xb0alubj 140 2 RNA RNA NNP cord-334550-xb0alubj 140 3 - - HYPH cord-334550-xb0alubj 140 4 dependent dependent JJ cord-334550-xb0alubj 140 5 RNA RNA NNP cord-334550-xb0alubj 140 6 polymerase polymerase NN cord-334550-xb0alubj 140 7 ( ( -LRB- cord-334550-xb0alubj 140 8 RdRP)/NSP12 rdrp)/nsp12 NN cord-334550-xb0alubj 140 9 protein protein NN cord-334550-xb0alubj 140 10 is be VBZ cord-334550-xb0alubj 140 11 an an DT cord-334550-xb0alubj 140 12 integral integral JJ cord-334550-xb0alubj 140 13 component component NN cord-334550-xb0alubj 140 14 of of IN cord-334550-xb0alubj 140 15 the the DT cord-334550-xb0alubj 140 16 viral viral JJ cord-334550-xb0alubj 140 17 replication replication NN cord-334550-xb0alubj 140 18 machinery machinery NN cord-334550-xb0alubj 140 19 and and CC cord-334550-xb0alubj 140 20 any any DT cord-334550-xb0alubj 140 21 mutation mutation NN cord-334550-xb0alubj 140 22 in in IN cord-334550-xb0alubj 140 23 this this DT cord-334550-xb0alubj 140 24 protein protein NN cord-334550-xb0alubj 140 25 might may MD cord-334550-xb0alubj 140 26 interfere interfere VB cord-334550-xb0alubj 140 27 with with IN cord-334550-xb0alubj 140 28 viral viral JJ cord-334550-xb0alubj 140 29 replication replication NN cord-334550-xb0alubj 140 30 and and CC cord-334550-xb0alubj 140 31 cause cause VB cord-334550-xb0alubj 140 32 accumulation accumulation NN cord-334550-xb0alubj 140 33 of of IN cord-334550-xb0alubj 140 34 novel novel NN cord-334550-xb0alubj 140 35 mutations mutation NNS cord-334550-xb0alubj 140 36 . . . cord-334550-xb0alubj 141 1 In in IN cord-334550-xb0alubj 141 2 Indian indian JJ cord-334550-xb0alubj 141 3 SARS SARS NNP cord-334550-xb0alubj 141 4 - - HYPH cord-334550-xb0alubj 141 5 CoV-2 CoV-2 NNP cord-334550-xb0alubj 141 6 strains strain NNS cord-334550-xb0alubj 141 7 , , , cord-334550-xb0alubj 141 8 two two CD cord-334550-xb0alubj 141 9 mutations mutation NNS cord-334550-xb0alubj 141 10 : : : cord-334550-xb0alubj 141 11 14408C 14408c LS cord-334550-xb0alubj 141 12 > > XX cord-334550-xb0alubj 141 13 T T NNP cord-334550-xb0alubj 141 14 ( ( -LRB- cord-334550-xb0alubj 141 15 P323L P323L NNP cord-334550-xb0alubj 141 16 ) ) -RRB- cord-334550-xb0alubj 141 17 and and CC cord-334550-xb0alubj 141 18 13730C 13730C NNP cord-334550-xb0alubj 141 19 > > XX cord-334550-xb0alubj 141 20 T t NN cord-334550-xb0alubj 141 21 ( ( -LRB- cord-334550-xb0alubj 141 22 A97V a97v NN cord-334550-xb0alubj 141 23 ) ) -RRB- cord-334550-xb0alubj 141 24 in in IN cord-334550-xb0alubj 141 25 RdRP rdrp NN cord-334550-xb0alubj 141 26 gene gene NN cord-334550-xb0alubj 141 27 have have VBP cord-334550-xb0alubj 141 28 been be VBN cord-334550-xb0alubj 141 29 documented document VBN cord-334550-xb0alubj 141 30 which which WDT cord-334550-xb0alubj 141 31 might may MD cord-334550-xb0alubj 141 32 have have VB cord-334550-xb0alubj 141 33 altered alter VBN cord-334550-xb0alubj 141 34 the the DT cord-334550-xb0alubj 141 35 secondary secondary JJ cord-334550-xb0alubj 141 36 structure structure NN cord-334550-xb0alubj 141 37 of of IN cord-334550-xb0alubj 141 38 RdRP RdRP NNP cord-334550-xb0alubj 141 39 and and CC cord-334550-xb0alubj 141 40 resulted result VBD cord-334550-xb0alubj 141 41 in in IN cord-334550-xb0alubj 141 42 simultaneous simultaneous JJ cord-334550-xb0alubj 141 43 emergence emergence NN cord-334550-xb0alubj 141 44 of of IN cord-334550-xb0alubj 141 45 major major JJ cord-334550-xb0alubj 141 46 and and CC cord-334550-xb0alubj 141 47 minor minor JJ cord-334550-xb0alubj 141 48 groups group NNS cord-334550-xb0alubj 141 49 of of IN cord-334550-xb0alubj 141 50 the the DT cord-334550-xb0alubj 141 51 virus virus NN cord-334550-xb0alubj 141 52 with with IN cord-334550-xb0alubj 141 53 characteristic characteristic JJ cord-334550-xb0alubj 141 54 co co JJ cord-334550-xb0alubj 141 55 - - JJ cord-334550-xb0alubj 141 56 evolving evolving JJ cord-334550-xb0alubj 141 57 mutations mutation NNS cord-334550-xb0alubj 141 58 ( ( -LRB- cord-334550-xb0alubj 141 59 Banerjee Banerjee NNP cord-334550-xb0alubj 141 60 et et NNP cord-334550-xb0alubj 141 61 al al NNP cord-334550-xb0alubj 141 62 . . NNP cord-334550-xb0alubj 141 63 , , , cord-334550-xb0alubj 141 64 2020 2020 CD cord-334550-xb0alubj 141 65 ) ) -RRB- cord-334550-xb0alubj 141 66 . . . cord-334550-xb0alubj 142 1 A a DT cord-334550-xb0alubj 142 2 study study NN cord-334550-xb0alubj 142 3 from from IN cord-334550-xb0alubj 142 4 University University NNP cord-334550-xb0alubj 142 5 of of IN cord-334550-xb0alubj 142 6 Bologna Bologna NNP cord-334550-xb0alubj 142 7 , , , cord-334550-xb0alubj 142 8 Italy Italy NNP cord-334550-xb0alubj 142 9 , , , cord-334550-xb0alubj 142 10 analyzed analyze VBD cord-334550-xb0alubj 142 11 10,014 10,014 CD cord-334550-xb0alubj 142 12 SARS SARS NNP cord-334550-xb0alubj 142 13 - - HYPH cord-334550-xb0alubj 142 14 CoV-2 CoV-2 NNP cord-334550-xb0alubj 142 15 genomic genomic JJ cord-334550-xb0alubj 142 16 sequences sequence NNS cord-334550-xb0alubj 142 17 in in IN cord-334550-xb0alubj 142 18 comparison comparison NN cord-334550-xb0alubj 142 19 with with IN cord-334550-xb0alubj 142 20 the the DT cord-334550-xb0alubj 142 21 reference reference NN cord-334550-xb0alubj 142 22 Wuhan Wuhan NNP cord-334550-xb0alubj 142 23 genome genome NN cord-334550-xb0alubj 142 24 and and CC cord-334550-xb0alubj 142 25 revealed reveal VBD cord-334550-xb0alubj 142 26 a a DT cord-334550-xb0alubj 142 27 low low JJ cord-334550-xb0alubj 142 28 mutation mutation NN cord-334550-xb0alubj 142 29 rate rate NN cord-334550-xb0alubj 142 30 of of IN cord-334550-xb0alubj 142 31 the the DT cord-334550-xb0alubj 142 32 virus virus NN cord-334550-xb0alubj 142 33 , , , cord-334550-xb0alubj 142 34 with with IN cord-334550-xb0alubj 142 35 an an DT cord-334550-xb0alubj 142 36 average average NN cord-334550-xb0alubj 142 37 of of IN cord-334550-xb0alubj 142 38 6.7 6.7 CD cord-334550-xb0alubj 142 39 mutations mutation NNS cord-334550-xb0alubj 142 40 per per IN cord-334550-xb0alubj 142 41 sample sample NN cord-334550-xb0alubj 142 42 with with IN cord-334550-xb0alubj 142 43 respect respect NN cord-334550-xb0alubj 142 44 to to IN cord-334550-xb0alubj 142 45 the the DT cord-334550-xb0alubj 142 46 reference reference NN cord-334550-xb0alubj 142 47 strain strain NN cord-334550-xb0alubj 142 48 . . . cord-334550-xb0alubj 143 1 According accord VBG cord-334550-xb0alubj 143 2 to to IN cord-334550-xb0alubj 143 3 the the DT cord-334550-xb0alubj 143 4 study study NN cord-334550-xb0alubj 143 5 , , , cord-334550-xb0alubj 143 6 SNPs SNPs NNPS cord-334550-xb0alubj 143 7 are be VBP cord-334550-xb0alubj 143 8 the the DT cord-334550-xb0alubj 143 9 most most RBS cord-334550-xb0alubj 143 10 common common JJ cord-334550-xb0alubj 143 11 mutational mutational JJ cord-334550-xb0alubj 143 12 events event NNS cord-334550-xb0alubj 143 13 observed observe VBN cord-334550-xb0alubj 143 14 worldwide worldwide RB cord-334550-xb0alubj 143 15 as as RB cord-334550-xb0alubj 143 16 well well RB cord-334550-xb0alubj 143 17 as as IN cord-334550-xb0alubj 143 18 in in IN cord-334550-xb0alubj 143 19 Asia Asia NNP cord-334550-xb0alubj 143 20 . . . cord-334550-xb0alubj 144 1 The the DT cord-334550-xb0alubj 144 2 most most RBS cord-334550-xb0alubj 144 3 common common JJ cord-334550-xb0alubj 144 4 mutation mutation NN cord-334550-xb0alubj 144 5 observed observe VBN cord-334550-xb0alubj 144 6 in in IN cord-334550-xb0alubj 144 7 Asia Asia NNP cord-334550-xb0alubj 144 8 is be VBZ cord-334550-xb0alubj 144 9 G11083 G11083 NNP cord-334550-xb0alubj 144 10 T T NNP cord-334550-xb0alubj 144 11 , , , cord-334550-xb0alubj 144 12 causing cause VBG cord-334550-xb0alubj 144 13 a a DT cord-334550-xb0alubj 144 14 SNP SNP NNP cord-334550-xb0alubj 144 15 at at IN cord-334550-xb0alubj 144 16 position position NN cord-334550-xb0alubj 144 17 37 37 CD cord-334550-xb0alubj 144 18 of of IN cord-334550-xb0alubj 144 19 theNSP6 theNSP6 NNP cord-334550-xb0alubj 144 20 . . . cord-334550-xb0alubj 145 1 Several several JJ cord-334550-xb0alubj 145 2 other other JJ cord-334550-xb0alubj 145 3 mutations mutation NNS cord-334550-xb0alubj 145 4 like like IN cord-334550-xb0alubj 145 5 ORF8 ORF8 NNP cord-334550-xb0alubj 145 6 : : : cord-334550-xb0alubj 145 7 L84S l84s NN cord-334550-xb0alubj 145 8 ( ( -LRB- cord-334550-xb0alubj 145 9 China China NNP cord-334550-xb0alubj 145 10 ) ) -RRB- cord-334550-xb0alubj 145 11 and and CC cord-334550-xb0alubj 145 12 ORF3a orf3a JJ cord-334550-xb0alubj 145 13 : : : cord-334550-xb0alubj 145 14 G251V G251V NNP cord-334550-xb0alubj 145 15 ( ( -LRB- cord-334550-xb0alubj 145 16 Hong Hong NNP cord-334550-xb0alubj 145 17 Kong Kong NNP cord-334550-xb0alubj 145 18 ) ) -RRB- cord-334550-xb0alubj 145 19 have have VBP cord-334550-xb0alubj 145 20 also also RB cord-334550-xb0alubj 145 21 been be VBN cord-334550-xb0alubj 145 22 documented document VBN cord-334550-xb0alubj 145 23 , , , cord-334550-xb0alubj 145 24 with with IN cord-334550-xb0alubj 145 25 a a DT cord-334550-xb0alubj 145 26 regional regional JJ cord-334550-xb0alubj 145 27 variation variation NN cord-334550-xb0alubj 145 28 in in IN cord-334550-xb0alubj 145 29 the the DT cord-334550-xb0alubj 145 30 type type NN cord-334550-xb0alubj 145 31 and and CC cord-334550-xb0alubj 145 32 nature nature NN cord-334550-xb0alubj 145 33 of of IN cord-334550-xb0alubj 145 34 such such JJ cord-334550-xb0alubj 145 35 events event NNS cord-334550-xb0alubj 145 36 ( ( -LRB- cord-334550-xb0alubj 145 37 Mercatelli Mercatelli NNP cord-334550-xb0alubj 145 38 and and CC cord-334550-xb0alubj 145 39 Giorgi Giorgi NNP cord-334550-xb0alubj 145 40 , , , cord-334550-xb0alubj 145 41 2020 2020 CD cord-334550-xb0alubj 145 42 ) ) -RRB- cord-334550-xb0alubj 145 43 . . . cord-334550-xb0alubj 146 1 A a DT cord-334550-xb0alubj 146 2 comparative comparative JJ cord-334550-xb0alubj 146 3 genomic genomic JJ cord-334550-xb0alubj 146 4 analysis analysis NN cord-334550-xb0alubj 146 5 of of IN cord-334550-xb0alubj 146 6 3067 3067 CD cord-334550-xb0alubj 146 7 SARS SARS NNP cord-334550-xb0alubj 146 8 - - HYPH cord-334550-xb0alubj 146 9 CoV-2 CoV-2 NNP cord-334550-xb0alubj 146 10 genomes genome NNS cord-334550-xb0alubj 146 11 from from IN cord-334550-xb0alubj 146 12 59 59 CD cord-334550-xb0alubj 146 13 countries country NNS cord-334550-xb0alubj 146 14 revealed reveal VBD cord-334550-xb0alubj 146 15 the the DT cord-334550-xb0alubj 146 16 presence presence NN cord-334550-xb0alubj 146 17 of of IN cord-334550-xb0alubj 146 18 singleton singleton NNP cord-334550-xb0alubj 146 19 mutations mutation NNS cord-334550-xb0alubj 146 20 in in IN cord-334550-xb0alubj 146 21 26 26 CD cord-334550-xb0alubj 146 22 countries country NNS cord-334550-xb0alubj 146 23 with with IN cord-334550-xb0alubj 146 24 United United NNP cord-334550-xb0alubj 146 25 States States NNP cord-334550-xb0alubj 146 26 accounting account VBG cord-334550-xb0alubj 146 27 for for IN cord-334550-xb0alubj 146 28 the the DT cord-334550-xb0alubj 146 29 highest high JJS cord-334550-xb0alubj 146 30 number number NN cord-334550-xb0alubj 146 31 of of IN cord-334550-xb0alubj 146 32 mutations mutation NNS cord-334550-xb0alubj 146 33 ( ( -LRB- cord-334550-xb0alubj 146 34 44 44 CD cord-334550-xb0alubj 146 35 % % NN cord-334550-xb0alubj 146 36 of of IN cord-334550-xb0alubj 146 37 total total JJ cord-334550-xb0alubj 146 38 mutations mutation NNS cord-334550-xb0alubj 146 39 ) ) -RRB- cord-334550-xb0alubj 146 40 . . . cord-334550-xb0alubj 147 1 The the DT cord-334550-xb0alubj 147 2 mutations mutation NNS cord-334550-xb0alubj 147 3 G251V G251V NNP cord-334550-xb0alubj 147 4 ( ( -LRB- cord-334550-xb0alubj 147 5 in in IN cord-334550-xb0alubj 147 6 ORF3a ORF3a NNP cord-334550-xb0alubj 147 7 ) ) -RRB- cord-334550-xb0alubj 147 8 , , , cord-334550-xb0alubj 147 9 L84S l84s NN cord-334550-xb0alubj 147 10 ( ( -LRB- cord-334550-xb0alubj 147 11 in in IN cord-334550-xb0alubj 147 12 ORF8 ORF8 NNP cord-334550-xb0alubj 147 13 ) ) -RRB- cord-334550-xb0alubj 147 14 and and CC cord-334550-xb0alubj 147 15 S5932F S5932F NNP cord-334550-xb0alubj 147 16 ( ( -LRB- cord-334550-xb0alubj 147 17 in in IN cord-334550-xb0alubj 147 18 ORF1ab ORF1ab NNP cord-334550-xb0alubj 147 19 ) ) -RRB- cord-334550-xb0alubj 147 20 exist exist VBP cord-334550-xb0alubj 147 21 in in IN cord-334550-xb0alubj 147 22 all all DT cord-334550-xb0alubj 147 23 continents continent NNS cord-334550-xb0alubj 147 24 except except IN cord-334550-xb0alubj 147 25 Africa Africa NNP cord-334550-xb0alubj 147 26 . . . cord-334550-xb0alubj 148 1 Also also RB cord-334550-xb0alubj 148 2 , , , cord-334550-xb0alubj 148 3 the the DT cord-334550-xb0alubj 148 4 genome genome NN cord-334550-xb0alubj 148 5 variability variability NN cord-334550-xb0alubj 148 6 is be VBZ cord-334550-xb0alubj 148 7 most most RBS cord-334550-xb0alubj 148 8 prominent prominent JJ cord-334550-xb0alubj 148 9 in in IN cord-334550-xb0alubj 148 10 America America NNP cord-334550-xb0alubj 148 11 , , , cord-334550-xb0alubj 148 12 Australia Australia NNP cord-334550-xb0alubj 148 13 and and CC cord-334550-xb0alubj 148 14 New New NNP cord-334550-xb0alubj 148 15 Zealand Zealand NNP cord-334550-xb0alubj 149 1 ( ( -LRB- cord-334550-xb0alubj 149 2 Laamarti Laamarti NNP cord-334550-xb0alubj 149 3 et et NNP cord-334550-xb0alubj 149 4 al al NNP cord-334550-xb0alubj 149 5 . . NNP cord-334550-xb0alubj 149 6 , , , cord-334550-xb0alubj 149 7 2020 2020 CD cord-334550-xb0alubj 149 8 ) ) -RRB- cord-334550-xb0alubj 149 9 . . . cord-334550-xb0alubj 150 1 Figure figure NN cord-334550-xb0alubj 150 2 1 1 CD cord-334550-xb0alubj 150 3 depicts depict VBZ cord-334550-xb0alubj 150 4 the the DT cord-334550-xb0alubj 150 5 geographic geographic JJ cord-334550-xb0alubj 150 6 and and CC cord-334550-xb0alubj 150 7 genomic genomic JJ cord-334550-xb0alubj 150 8 distribution distribution NN cord-334550-xb0alubj 150 9 of of IN cord-334550-xb0alubj 150 10 SARS SARS NNP cord-334550-xb0alubj 150 11 - - HYPH cord-334550-xb0alubj 150 12 CoV-2 CoV-2 NNP cord-334550-xb0alubj 150 13 mutations mutation NNS cord-334550-xb0alubj 150 14 . . . cord-334550-xb0alubj 151 1 Such such JJ cord-334550-xb0alubj 151 2 genomic genomic JJ cord-334550-xb0alubj 151 3 diversity diversity NN cord-334550-xb0alubj 151 4 may may MD cord-334550-xb0alubj 151 5 give give VB cord-334550-xb0alubj 151 6 rise rise NN cord-334550-xb0alubj 151 7 to to IN cord-334550-xb0alubj 151 8 new new JJ cord-334550-xb0alubj 151 9 clades clade NNS cord-334550-xb0alubj 151 10 with with IN cord-334550-xb0alubj 151 11 variations variation NNS cord-334550-xb0alubj 151 12 in in IN cord-334550-xb0alubj 151 13 transcription transcription NN cord-334550-xb0alubj 151 14 and and CC cord-334550-xb0alubj 151 15 replication replication NN cord-334550-xb0alubj 151 16 rates rate NNS cord-334550-xb0alubj 151 17 , , , cord-334550-xb0alubj 151 18 which which WDT cord-334550-xb0alubj 151 19 in in IN cord-334550-xb0alubj 151 20 turn turn NN cord-334550-xb0alubj 151 21 may may MD cord-334550-xb0alubj 151 22 affect affect VB cord-334550-xb0alubj 151 23 virulence virulence NN cord-334550-xb0alubj 151 24 and and CC cord-334550-xb0alubj 151 25 transmissibility transmissibility NN cord-334550-xb0alubj 151 26 . . . cord-334550-xb0alubj 152 1 Studies study NNS cord-334550-xb0alubj 152 2 combining combine VBG cord-334550-xb0alubj 152 3 genomic genomic JJ cord-334550-xb0alubj 152 4 details detail NNS cord-334550-xb0alubj 152 5 with with IN cord-334550-xb0alubj 152 6 demographic demographic JJ cord-334550-xb0alubj 152 7 and and CC cord-334550-xb0alubj 152 8 epidemiological epidemiological JJ cord-334550-xb0alubj 152 9 data datum NNS cord-334550-xb0alubj 152 10 are be VBP cord-334550-xb0alubj 152 11 essential essential JJ cord-334550-xb0alubj 152 12 to to TO cord-334550-xb0alubj 152 13 identify identify VB cord-334550-xb0alubj 152 14 any any DT cord-334550-xb0alubj 152 15 ongoing ongoing JJ cord-334550-xb0alubj 152 16 mutation mutation NN cord-334550-xb0alubj 152 17 and and CC cord-334550-xb0alubj 152 18 its -PRON- PRP$ cord-334550-xb0alubj 152 19 impact impact NN cord-334550-xb0alubj 152 20 on on IN cord-334550-xb0alubj 152 21 virulence virulence NN cord-334550-xb0alubj 152 22 and and CC cord-334550-xb0alubj 152 23 severity severity NN cord-334550-xb0alubj 152 24 of of IN cord-334550-xb0alubj 152 25 the the DT cord-334550-xb0alubj 152 26 disease disease NN cord-334550-xb0alubj 152 27 across across IN cord-334550-xb0alubj 152 28 populations population NNS cord-334550-xb0alubj 152 29 . . . cord-334550-xb0alubj 153 1 A a DT cord-334550-xb0alubj 153 2 comparative comparative JJ cord-334550-xb0alubj 153 3 analysis analysis NN cord-334550-xb0alubj 153 4 of of IN cord-334550-xb0alubj 153 5 the the DT cord-334550-xb0alubj 153 6 immune immune JJ cord-334550-xb0alubj 153 7 phenotypes phenotype NNS cord-334550-xb0alubj 153 8 in in IN cord-334550-xb0alubj 153 9 Indian indian JJ cord-334550-xb0alubj 153 10 and and CC cord-334550-xb0alubj 153 11 American american JJ cord-334550-xb0alubj 153 12 newborns newborn NNS cord-334550-xb0alubj 153 13 revealed reveal VBD cord-334550-xb0alubj 153 14 that that IN cord-334550-xb0alubj 153 15 Indian indian JJ cord-334550-xb0alubj 153 16 infants infant NNS cord-334550-xb0alubj 153 17 had have VBD cord-334550-xb0alubj 153 18 a a DT cord-334550-xb0alubj 153 19 higher high JJR cord-334550-xb0alubj 153 20 proportion proportion NN cord-334550-xb0alubj 153 21 of of IN cord-334550-xb0alubj 153 22 dendritic dendritic JJ cord-334550-xb0alubj 153 23 cells cell NNS cord-334550-xb0alubj 153 24 , , , cord-334550-xb0alubj 153 25 monocytes monocyte NNS cord-334550-xb0alubj 153 26 , , , cord-334550-xb0alubj 153 27 natural natural JJ cord-334550-xb0alubj 153 28 killer killer NN cord-334550-xb0alubj 153 29 ( ( -LRB- cord-334550-xb0alubj 153 30 NK NK NNP cord-334550-xb0alubj 153 31 ) ) -RRB- cord-334550-xb0alubj 153 32 cells cell NNS cord-334550-xb0alubj 153 33 , , , cord-334550-xb0alubj 153 34 memory memory NN cord-334550-xb0alubj 153 35 CD4 CD4 NNP cord-334550-xb0alubj 153 36 + + CC cord-334550-xb0alubj 153 37 T t NN cord-334550-xb0alubj 153 38 cells cell NNS cord-334550-xb0alubj 153 39 , , , cord-334550-xb0alubj 153 40 and and CC cord-334550-xb0alubj 153 41 naïve naïve JJ cord-334550-xb0alubj 153 42 B B NNP cord-334550-xb0alubj 153 43 cells cell NNS cord-334550-xb0alubj 153 44 , , , cord-334550-xb0alubj 153 45 compared compare VBN cord-334550-xb0alubj 153 46 to to IN cord-334550-xb0alubj 153 47 American american JJ cord-334550-xb0alubj 153 48 infants infant NNS cord-334550-xb0alubj 153 49 ( ( -LRB- cord-334550-xb0alubj 153 50 Rathore Rathore NNP cord-334550-xb0alubj 153 51 et et FW cord-334550-xb0alubj 153 52 al al NNP cord-334550-xb0alubj 153 53 . . NNP cord-334550-xb0alubj 153 54 , , , cord-334550-xb0alubj 153 55 2018 2018 CD cord-334550-xb0alubj 153 56 ) ) -RRB- cord-334550-xb0alubj 153 57 . . . cord-334550-xb0alubj 154 1 Such such JJ cord-334550-xb0alubj 154 2 variations variation NNS cord-334550-xb0alubj 154 3 in in IN cord-334550-xb0alubj 154 4 immune immune JJ cord-334550-xb0alubj 154 5 systems system NNS cord-334550-xb0alubj 154 6 can can MD cord-334550-xb0alubj 154 7 be be VB cord-334550-xb0alubj 154 8 attributed attribute VBN cord-334550-xb0alubj 154 9 to to IN cord-334550-xb0alubj 154 10 heritable heritable JJ cord-334550-xb0alubj 154 11 and and CC cord-334550-xb0alubj 154 12 nonheritable nonheritable JJ cord-334550-xb0alubj 154 13 influences influence NNS cord-334550-xb0alubj 154 14 . . . cord-334550-xb0alubj 155 1 Heritable heritable JJ cord-334550-xb0alubj 155 2 factors factor NNS cord-334550-xb0alubj 155 3 have have VBP cord-334550-xb0alubj 155 4 germline germline JJ cord-334550-xb0alubj 155 5 inheritance inheritance NN cord-334550-xb0alubj 155 6 and and CC cord-334550-xb0alubj 155 7 have have VB cord-334550-xb0alubj 155 8 a a DT cord-334550-xb0alubj 155 9 minor minor JJ cord-334550-xb0alubj 155 10 influence influence NN cord-334550-xb0alubj 155 11 on on IN cord-334550-xb0alubj 155 12 inter inter JJ cord-334550-xb0alubj 155 13 - - JJ cord-334550-xb0alubj 155 14 individual individual JJ cord-334550-xb0alubj 155 15 and and CC cord-334550-xb0alubj 155 16 population population NN cord-334550-xb0alubj 155 17 variation variation NN cord-334550-xb0alubj 155 18 in in IN cord-334550-xb0alubj 155 19 immune immune JJ cord-334550-xb0alubj 155 20 responses response NNS cord-334550-xb0alubj 155 21 ( ( -LRB- cord-334550-xb0alubj 155 22 Brodin Brodin NNP cord-334550-xb0alubj 155 23 et et NNP cord-334550-xb0alubj 155 24 al al NNP cord-334550-xb0alubj 155 25 . . NNP cord-334550-xb0alubj 155 26 , , , cord-334550-xb0alubj 155 27 2015 2015 CD cord-334550-xb0alubj 155 28 ; ; : cord-334550-xb0alubj 155 29 Brodin Brodin NNP cord-334550-xb0alubj 155 30 and and CC cord-334550-xb0alubj 155 31 Davis Davis NNP cord-334550-xb0alubj 155 32 , , , cord-334550-xb0alubj 155 33 2017 2017 CD cord-334550-xb0alubj 155 34 ) ) -RRB- cord-334550-xb0alubj 155 35 . . . cord-334550-xb0alubj 156 1 A a DT cord-334550-xb0alubj 156 2 population population NN cord-334550-xb0alubj 156 3 - - HYPH cord-334550-xb0alubj 156 4 based base VBN cord-334550-xb0alubj 156 5 cohort cohort NN cord-334550-xb0alubj 156 6 study study NN cord-334550-xb0alubj 156 7 ( ( -LRB- cord-334550-xb0alubj 156 8 ImmVar immvar NN cord-334550-xb0alubj 156 9 project project NN cord-334550-xb0alubj 156 10 ) ) -RRB- cord-334550-xb0alubj 156 11 involving involve VBG cord-334550-xb0alubj 156 12 subjects subject NNS cord-334550-xb0alubj 156 13 of of IN cord-334550-xb0alubj 156 14 African african JJ cord-334550-xb0alubj 156 15 - - HYPH cord-334550-xb0alubj 156 16 American american JJ cord-334550-xb0alubj 156 17 , , , cord-334550-xb0alubj 156 18 East east JJ cord-334550-xb0alubj 156 19 Asian asian JJ cord-334550-xb0alubj 156 20 and and CC cord-334550-xb0alubj 156 21 European european JJ cord-334550-xb0alubj 156 22 ancestry ancestry NN cord-334550-xb0alubj 156 23 analyzed analyze VBD cord-334550-xb0alubj 156 24 the the DT cord-334550-xb0alubj 156 25 variability variability NN cord-334550-xb0alubj 156 26 in in IN cord-334550-xb0alubj 156 27 functional functional JJ cord-334550-xb0alubj 156 28 responses response NNS cord-334550-xb0alubj 156 29 of of IN cord-334550-xb0alubj 156 30 T T NNP cord-334550-xb0alubj 156 31 - - HYPH cord-334550-xb0alubj 156 32 cells cell NNS cord-334550-xb0alubj 156 33 and and CC cord-334550-xb0alubj 156 34 dendritic dendritic JJ cord-334550-xb0alubj 156 35 cells cell NNS cord-334550-xb0alubj 156 36 by by IN cord-334550-xb0alubj 156 37 gene gene NN cord-334550-xb0alubj 156 38 profiling profiling NN cord-334550-xb0alubj 156 39 and and CC cord-334550-xb0alubj 156 40 concluded conclude VBD cord-334550-xb0alubj 156 41 that that IN cord-334550-xb0alubj 156 42 heritable heritable JJ cord-334550-xb0alubj 156 43 factors factor NNS cord-334550-xb0alubj 156 44 accounted account VBD cord-334550-xb0alubj 156 45 for for IN cord-334550-xb0alubj 156 46 only only RB cord-334550-xb0alubj 156 47 22 22 CD cord-334550-xb0alubj 156 48 % % NN cord-334550-xb0alubj 156 49 of of IN cord-334550-xb0alubj 156 50 the the DT cord-334550-xb0alubj 156 51 overall overall JJ cord-334550-xb0alubj 156 52 variation variation NN cord-334550-xb0alubj 156 53 in in IN cord-334550-xb0alubj 156 54 gene gene NN cord-334550-xb0alubj 156 55 expression expression NN cord-334550-xb0alubj 156 56 ( ( -LRB- cord-334550-xb0alubj 156 57 De De NNP cord-334550-xb0alubj 156 58 Jager Jager NNP cord-334550-xb0alubj 156 59 et et NNP cord-334550-xb0alubj 156 60 al al NNP cord-334550-xb0alubj 156 61 . . NNP cord-334550-xb0alubj 156 62 , , , cord-334550-xb0alubj 156 63 2015 2015 CD cord-334550-xb0alubj 156 64 ) ) -RRB- cord-334550-xb0alubj 156 65 . . . cord-334550-xb0alubj 157 1 Non non JJ cord-334550-xb0alubj 157 2 - - JJ cord-334550-xb0alubj 157 3 heritable heritable JJ cord-334550-xb0alubj 157 4 factors factor NNS cord-334550-xb0alubj 157 5 include include VBP cord-334550-xb0alubj 157 6 environmental environmental JJ cord-334550-xb0alubj 157 7 influences influence NNS cord-334550-xb0alubj 157 8 , , , cord-334550-xb0alubj 157 9 such such JJ cord-334550-xb0alubj 157 10 as as IN cord-334550-xb0alubj 157 11 infections infection NNS cord-334550-xb0alubj 157 12 and and CC cord-334550-xb0alubj 157 13 vaccines vaccine NNS cord-334550-xb0alubj 157 14 , , , cord-334550-xb0alubj 157 15 stochastic stochastic JJ cord-334550-xb0alubj 157 16 epigenetic epigenetic JJ cord-334550-xb0alubj 157 17 changes change NNS cord-334550-xb0alubj 157 18 arising arise VBG cord-334550-xb0alubj 157 19 from from IN cord-334550-xb0alubj 157 20 imperfect imperfect JJ cord-334550-xb0alubj 157 21 replication replication NN cord-334550-xb0alubj 157 22 machinery machinery NN cord-334550-xb0alubj 157 23 , , , cord-334550-xb0alubj 157 24 and and CC cord-334550-xb0alubj 157 25 symbiotic symbiotic JJ cord-334550-xb0alubj 157 26 and and CC cord-334550-xb0alubj 157 27 pathogenic pathogenic JJ cord-334550-xb0alubj 157 28 microbes microbe NNS cord-334550-xb0alubj 157 29 . . . cord-334550-xb0alubj 158 1 Non non JJ cord-334550-xb0alubj 158 2 - - JJ cord-334550-xb0alubj 158 3 heritable heritable JJ cord-334550-xb0alubj 158 4 influences influence NNS cord-334550-xb0alubj 158 5 are be VBP cord-334550-xb0alubj 158 6 the the DT cord-334550-xb0alubj 158 7 major major JJ cord-334550-xb0alubj 158 8 factors factor NNS cord-334550-xb0alubj 158 9 determining determine VBG cord-334550-xb0alubj 158 10 immune immune JJ cord-334550-xb0alubj 158 11 variation variation NN cord-334550-xb0alubj 158 12 ( ( -LRB- cord-334550-xb0alubj 158 13 Brodin Brodin NNP cord-334550-xb0alubj 158 14 et et NNP cord-334550-xb0alubj 158 15 al al NNP cord-334550-xb0alubj 158 16 . . NNP cord-334550-xb0alubj 158 17 , , , cord-334550-xb0alubj 158 18 2015 2015 CD cord-334550-xb0alubj 158 19 ; ; . cord-334550-xb0alubj 159 1 Brodin Brodin NNP cord-334550-xb0alubj 159 2 and and CC cord-334550-xb0alubj 159 3 Davis Davis NNP cord-334550-xb0alubj 159 4 , , , cord-334550-xb0alubj 159 5 2017 2017 CD cord-334550-xb0alubj 159 6 ) ) -RRB- cord-334550-xb0alubj 159 7 . . . cord-334550-xb0alubj 160 1 Brodin Brodin NNP cord-334550-xb0alubj 160 2 et et NNP cord-334550-xb0alubj 160 3 al al NNP cord-334550-xb0alubj 160 4 . . . cord-334550-xb0alubj 161 1 ( ( -LRB- cord-334550-xb0alubj 161 2 2015 2015 CD cord-334550-xb0alubj 161 3 ) ) -RRB- cord-334550-xb0alubj 161 4 analyzed analyze VBD cord-334550-xb0alubj 161 5 various various JJ cord-334550-xb0alubj 161 6 immunological immunological JJ cord-334550-xb0alubj 161 7 parameters parameter NNS cord-334550-xb0alubj 161 8 , , , cord-334550-xb0alubj 161 9 such such JJ cord-334550-xb0alubj 161 10 as as IN cord-334550-xb0alubj 161 11 cell cell NN cord-334550-xb0alubj 161 12 population population NN cord-334550-xb0alubj 161 13 frequencies frequency NNS cord-334550-xb0alubj 161 14 , , , cord-334550-xb0alubj 161 15 cytokine cytokine NN cord-334550-xb0alubj 161 16 responses response NNS cord-334550-xb0alubj 161 17 , , , cord-334550-xb0alubj 161 18 and and CC cord-334550-xb0alubj 161 19 serum serum NN cord-334550-xb0alubj 161 20 proteins protein NNS cord-334550-xb0alubj 161 21 in in IN cord-334550-xb0alubj 161 22 210 210 CD cord-334550-xb0alubj 161 23 healthy healthy JJ cord-334550-xb0alubj 161 24 twins twin NNS cord-334550-xb0alubj 161 25 and and CC cord-334550-xb0alubj 161 26 found find VBD cord-334550-xb0alubj 161 27 that that DT cord-334550-xb0alubj 161 28 majority majority NN cord-334550-xb0alubj 161 29 of of IN cord-334550-xb0alubj 161 30 these these DT cord-334550-xb0alubj 161 31 determinants determinant NNS cord-334550-xb0alubj 161 32 are be VBP cord-334550-xb0alubj 161 33 dominated dominate VBN cord-334550-xb0alubj 161 34 by by IN cord-334550-xb0alubj 161 35 non non JJ cord-334550-xb0alubj 161 36 - - JJ cord-334550-xb0alubj 161 37 heritable heritable JJ cord-334550-xb0alubj 161 38 influences influence NNS cord-334550-xb0alubj 161 39 , , , cord-334550-xb0alubj 161 40 indicating indicate VBG cord-334550-xb0alubj 161 41 that that IN cord-334550-xb0alubj 161 42 the the DT cord-334550-xb0alubj 161 43 human human JJ cord-334550-xb0alubj 161 44 immune immune NN cord-334550-xb0alubj 161 45 system system NN cord-334550-xb0alubj 161 46 is be VBZ cord-334550-xb0alubj 161 47 very very RB cord-334550-xb0alubj 161 48 much much RB cord-334550-xb0alubj 161 49 shaped shape VBN cord-334550-xb0alubj 161 50 by by IN cord-334550-xb0alubj 161 51 the the DT cord-334550-xb0alubj 161 52 environment environment NN cord-334550-xb0alubj 161 53 and and CC cord-334550-xb0alubj 161 54 the the DT cord-334550-xb0alubj 161 55 variety variety NN cord-334550-xb0alubj 161 56 of of IN cord-334550-xb0alubj 161 57 microbes microbe NNS cord-334550-xb0alubj 161 58 that that WDT cord-334550-xb0alubj 161 59 an an DT cord-334550-xb0alubj 161 60 individual individual JJ cord-334550-xb0alubj 161 61 encounters encounter VBZ cord-334550-xb0alubj 161 62 in in IN cord-334550-xb0alubj 161 63 their -PRON- PRP$ cord-334550-xb0alubj 161 64 lifetime lifetime NN cord-334550-xb0alubj 161 65 , , , cord-334550-xb0alubj 161 66 Besides besides IN cord-334550-xb0alubj 161 67 these these DT cord-334550-xb0alubj 161 68 factors factor NNS cord-334550-xb0alubj 161 69 , , , cord-334550-xb0alubj 161 70 India India NNP cord-334550-xb0alubj 161 71 has have VBZ cord-334550-xb0alubj 161 72 an an DT cord-334550-xb0alubj 161 73 overwhelming overwhelming JJ cord-334550-xb0alubj 161 74 burden burden NN cord-334550-xb0alubj 161 75 of of IN cord-334550-xb0alubj 161 76 tuberculosis tuberculosis NN cord-334550-xb0alubj 161 77 , , , cord-334550-xb0alubj 161 78 malaria malaria NN cord-334550-xb0alubj 161 79 and and CC cord-334550-xb0alubj 161 80 HIV HIV NNP cord-334550-xb0alubj 161 81 , , , cord-334550-xb0alubj 161 82 much much RB cord-334550-xb0alubj 161 83 higher high JJR cord-334550-xb0alubj 161 84 than than IN cord-334550-xb0alubj 161 85 the the DT cord-334550-xb0alubj 161 86 developed develop VBN cord-334550-xb0alubj 161 87 countries country NNS cord-334550-xb0alubj 161 88 . . . cord-334550-xb0alubj 162 1 Due due IN cord-334550-xb0alubj 162 2 to to IN cord-334550-xb0alubj 162 3 such such JJ cord-334550-xb0alubj 162 4 endemicity endemicity NN cord-334550-xb0alubj 162 5 , , , cord-334550-xb0alubj 162 6 Indians Indians NNPS cord-334550-xb0alubj 162 7 are be VBP cord-334550-xb0alubj 162 8 constantly constantly RB cord-334550-xb0alubj 162 9 subjected subject VBN cord-334550-xb0alubj 162 10 to to IN cord-334550-xb0alubj 162 11 pathogen pathogen NN cord-334550-xb0alubj 162 12 - - HYPH cord-334550-xb0alubj 162 13 assault assault NN cord-334550-xb0alubj 162 14 , , , cord-334550-xb0alubj 162 15 giving give VBG cord-334550-xb0alubj 162 16 rise rise NN cord-334550-xb0alubj 162 17 to to IN cord-334550-xb0alubj 162 18 a a DT cord-334550-xb0alubj 162 19 more more RBR cord-334550-xb0alubj 162 20 proactive proactive JJ cord-334550-xb0alubj 162 21 cell cell NN cord-334550-xb0alubj 162 22 - - HYPH cord-334550-xb0alubj 162 23 mediated mediate VBN cord-334550-xb0alubj 162 24 immune immune JJ cord-334550-xb0alubj 162 25 system system NN cord-334550-xb0alubj 162 26 , , , cord-334550-xb0alubj 162 27 than than IN cord-334550-xb0alubj 162 28 the the DT cord-334550-xb0alubj 162 29 western western JJ cord-334550-xb0alubj 162 30 population population NN cord-334550-xb0alubj 162 31 . . . cord-334550-xb0alubj 163 1 Also also RB cord-334550-xb0alubj 163 2 , , , cord-334550-xb0alubj 163 3 chloroquine chloroquine NN cord-334550-xb0alubj 163 4 and and CC cord-334550-xb0alubj 163 5 hydroxychloroquine hydroxychloroquine NNP cord-334550-xb0alubj 163 6 , , , cord-334550-xb0alubj 163 7 the the DT cord-334550-xb0alubj 163 8 two two CD cord-334550-xb0alubj 163 9 most most RBS cord-334550-xb0alubj 163 10 revered revered JJ cord-334550-xb0alubj 163 11 drugs drug NNS cord-334550-xb0alubj 163 12 in in IN cord-334550-xb0alubj 163 13 the the DT cord-334550-xb0alubj 163 14 context context NN cord-334550-xb0alubj 163 15 of of IN cord-334550-xb0alubj 163 16 COVID-19 COVID-19 NNP cord-334550-xb0alubj 163 17 treatment treatment NN cord-334550-xb0alubj 163 18 , , , cord-334550-xb0alubj 163 19 have have VBP cord-334550-xb0alubj 163 20 been be VBN cord-334550-xb0alubj 163 21 extensively extensively RB cord-334550-xb0alubj 163 22 used use VBN cord-334550-xb0alubj 163 23 at at IN cord-334550-xb0alubj 163 24 community community NN cord-334550-xb0alubj 163 25 level level NN cord-334550-xb0alubj 163 26 in in IN cord-334550-xb0alubj 163 27 India India NNP cord-334550-xb0alubj 163 28 for for IN cord-334550-xb0alubj 163 29 the the DT cord-334550-xb0alubj 163 30 prevention prevention NN cord-334550-xb0alubj 163 31 and and CC cord-334550-xb0alubj 163 32 treatment treatment NN cord-334550-xb0alubj 163 33 of of IN cord-334550-xb0alubj 163 34 malaria malaria NN cord-334550-xb0alubj 163 35 . . . cord-334550-xb0alubj 164 1 8 8 CD cord-334550-xb0alubj 165 1 Given give VBN cord-334550-xb0alubj 165 2 the the DT cord-334550-xb0alubj 165 3 immunomodulatory immunomodulatory JJ cord-334550-xb0alubj 165 4 and and CC cord-334550-xb0alubj 165 5 antiviral antiviral JJ cord-334550-xb0alubj 165 6 properties property NNS cord-334550-xb0alubj 165 7 of of IN cord-334550-xb0alubj 165 8 these these DT cord-334550-xb0alubj 165 9 drugs drug NNS cord-334550-xb0alubj 165 10 , , , cord-334550-xb0alubj 165 11 their -PRON- PRP$ cord-334550-xb0alubj 165 12 widespread widespread JJ cord-334550-xb0alubj 165 13 usage usage NN cord-334550-xb0alubj 165 14 might may MD cord-334550-xb0alubj 165 15 have have VB cord-334550-xb0alubj 165 16 contributed contribute VBN cord-334550-xb0alubj 165 17 to to IN cord-334550-xb0alubj 165 18 defense defense NN cord-334550-xb0alubj 165 19 against against IN cord-334550-xb0alubj 165 20 SARS SARS NNP cord-334550-xb0alubj 165 21 - - HYPH cord-334550-xb0alubj 165 22 CoV-2 CoV-2 NNP cord-334550-xb0alubj 165 23 . . . cord-334550-xb0alubj 166 1 Second second RB cord-334550-xb0alubj 166 2 , , , cord-334550-xb0alubj 166 3 the the DT cord-334550-xb0alubj 166 4 epigenetic epigenetic JJ cord-334550-xb0alubj 166 5 factors factor NNS cord-334550-xb0alubj 166 6 like like IN cord-334550-xb0alubj 166 7 environment environment NN cord-334550-xb0alubj 166 8 and and CC cord-334550-xb0alubj 166 9 food food NN cord-334550-xb0alubj 166 10 habits habit NNS cord-334550-xb0alubj 166 11 might may MD cord-334550-xb0alubj 166 12 have have VB cord-334550-xb0alubj 166 13 some some DT cord-334550-xb0alubj 166 14 role role NN cord-334550-xb0alubj 166 15 in in IN cord-334550-xb0alubj 166 16 boosting boost VBG cord-334550-xb0alubj 166 17 immunity immunity NN cord-334550-xb0alubj 166 18 . . . cord-334550-xb0alubj 167 1 Several several JJ cord-334550-xb0alubj 167 2 kinds kind NNS cord-334550-xb0alubj 167 3 of of IN cord-334550-xb0alubj 167 4 herbs herb NNS cord-334550-xb0alubj 167 5 and and CC cord-334550-xb0alubj 167 6 spices spice NNS cord-334550-xb0alubj 167 7 like like IN cord-334550-xb0alubj 167 8 turmeric turmeric NN cord-334550-xb0alubj 167 9 , , , cord-334550-xb0alubj 167 10 cloves clove NNS cord-334550-xb0alubj 167 11 , , , cord-334550-xb0alubj 167 12 ginger ginger NN cord-334550-xb0alubj 167 13 , , , cord-334550-xb0alubj 167 14 mustard mustard NN cord-334550-xb0alubj 167 15 , , , cord-334550-xb0alubj 167 16 saffron saffron NN cord-334550-xb0alubj 167 17 , , , cord-334550-xb0alubj 167 18 cardamom cardamom NN cord-334550-xb0alubj 167 19 , , , cord-334550-xb0alubj 167 20 and and CC cord-334550-xb0alubj 167 21 garlic garlic NN cord-334550-xb0alubj 167 22 are be VBP cord-334550-xb0alubj 167 23 essential essential JJ cord-334550-xb0alubj 167 24 ingredients ingredient NNS cord-334550-xb0alubj 167 25 of of IN cord-334550-xb0alubj 167 26 the the DT cord-334550-xb0alubj 167 27 Indian indian JJ cord-334550-xb0alubj 167 28 cuisine cuisine NN cord-334550-xb0alubj 167 29 . . . cord-334550-xb0alubj 168 1 These these DT cord-334550-xb0alubj 168 2 spices spice NNS cord-334550-xb0alubj 168 3 are be VBP cord-334550-xb0alubj 168 4 rich rich JJ cord-334550-xb0alubj 168 5 in in IN cord-334550-xb0alubj 168 6 bioactive bioactive JJ cord-334550-xb0alubj 168 7 compounds compound NNS cord-334550-xb0alubj 168 8 and and CC cord-334550-xb0alubj 168 9 phytochemicals phytochemical NNS cord-334550-xb0alubj 168 10 which which WDT cord-334550-xb0alubj 168 11 possess possess VBP cord-334550-xb0alubj 168 12 medicinal medicinal JJ cord-334550-xb0alubj 168 13 properties property NNS cord-334550-xb0alubj 168 14 ( ( -LRB- cord-334550-xb0alubj 168 15 Sengupta Sengupta NNP cord-334550-xb0alubj 168 16 et et NNP cord-334550-xb0alubj 168 17 al al NNP cord-334550-xb0alubj 168 18 . . NNP cord-334550-xb0alubj 168 19 , , , cord-334550-xb0alubj 168 20 2004 2004 CD cord-334550-xb0alubj 168 21 ) ) -RRB- cord-334550-xb0alubj 168 22 . . . cord-334550-xb0alubj 169 1 Turmeric turmeric NN cord-334550-xb0alubj 169 2 ( ( -LRB- cord-334550-xb0alubj 169 3 Indian indian JJ cord-334550-xb0alubj 169 4 saffron saffron NN cord-334550-xb0alubj 169 5 ) ) -RRB- cord-334550-xb0alubj 169 6 , , , cord-334550-xb0alubj 169 7 a a DT cord-334550-xb0alubj 169 8 product product NN cord-334550-xb0alubj 169 9 of of IN cord-334550-xb0alubj 169 10 Curcuma Curcuma NNP cord-334550-xb0alubj 169 11 longa longa NN cord-334550-xb0alubj 169 12 , , , cord-334550-xb0alubj 169 13 is be VBZ cord-334550-xb0alubj 169 14 a a DT cord-334550-xb0alubj 169 15 rhizomatous rhizomatous JJ cord-334550-xb0alubj 169 16 herbaceous herbaceous JJ cord-334550-xb0alubj 169 17 perennial perennial JJ cord-334550-xb0alubj 169 18 plant plant NN cord-334550-xb0alubj 169 19 belonging belong VBG cord-334550-xb0alubj 169 20 to to IN cord-334550-xb0alubj 169 21 the the DT cord-334550-xb0alubj 169 22 ginger ginger NN cord-334550-xb0alubj 169 23 family family NN cord-334550-xb0alubj 169 24 that that WDT cord-334550-xb0alubj 169 25 is be VBZ cord-334550-xb0alubj 169 26 routinely routinely RB cord-334550-xb0alubj 169 27 used use VBN cord-334550-xb0alubj 169 28 in in IN cord-334550-xb0alubj 169 29 Indian indian JJ cord-334550-xb0alubj 169 30 households household NNS cord-334550-xb0alubj 169 31 as as IN cord-334550-xb0alubj 169 32 a a DT cord-334550-xb0alubj 169 33 culinary culinary JJ cord-334550-xb0alubj 169 34 spice spice NN cord-334550-xb0alubj 169 35 and and CC cord-334550-xb0alubj 169 36 as as IN cord-334550-xb0alubj 169 37 a a DT cord-334550-xb0alubj 169 38 component component NN cord-334550-xb0alubj 169 39 in in IN cord-334550-xb0alubj 169 40 religious religious JJ cord-334550-xb0alubj 169 41 ceremonies ceremony NNS cord-334550-xb0alubj 169 42 . . . cord-334550-xb0alubj 170 1 It -PRON- PRP cord-334550-xb0alubj 170 2 has have VBZ cord-334550-xb0alubj 170 3 also also RB cord-334550-xb0alubj 170 4 been be VBN cord-334550-xb0alubj 170 5 used use VBN cord-334550-xb0alubj 170 6 as as IN cord-334550-xb0alubj 170 7 a a DT cord-334550-xb0alubj 170 8 traditional traditional JJ cord-334550-xb0alubj 170 9 medicine medicine NN cord-334550-xb0alubj 170 10 over over IN cord-334550-xb0alubj 170 11 centuries century NNS cord-334550-xb0alubj 170 12 . . . cord-334550-xb0alubj 171 1 Curcumin curcumin NN cord-334550-xb0alubj 171 2 , , , cord-334550-xb0alubj 171 3 the the DT cord-334550-xb0alubj 171 4 bioactive bioactive JJ cord-334550-xb0alubj 171 5 compound compound NN cord-334550-xb0alubj 171 6 in in IN cord-334550-xb0alubj 171 7 turmeric turmeric NN cord-334550-xb0alubj 171 8 has have VBZ cord-334550-xb0alubj 171 9 been be VBN cord-334550-xb0alubj 171 10 recognized recognize VBN cord-334550-xb0alubj 171 11 for for IN cord-334550-xb0alubj 171 12 its -PRON- PRP$ cord-334550-xb0alubj 171 13 potent potent JJ cord-334550-xb0alubj 171 14 antioxidant antioxidant NN cord-334550-xb0alubj 171 15 , , , cord-334550-xb0alubj 171 16 anti anti JJ cord-334550-xb0alubj 171 17 - - JJ cord-334550-xb0alubj 171 18 inflammatory inflammatory JJ cord-334550-xb0alubj 171 19 , , , cord-334550-xb0alubj 171 20 antimutagenic antimutagenic NNP cord-334550-xb0alubj 171 21 , , , cord-334550-xb0alubj 171 22 antimicrobial antimicrobial JJ cord-334550-xb0alubj 171 23 , , , cord-334550-xb0alubj 171 24 and and CC cord-334550-xb0alubj 171 25 anticancer anticancer JJ cord-334550-xb0alubj 171 26 properties property NNS cord-334550-xb0alubj 171 27 . . . cord-334550-xb0alubj 172 1 It -PRON- PRP cord-334550-xb0alubj 172 2 has have VBZ cord-334550-xb0alubj 172 3 demonstrated demonstrate VBN cord-334550-xb0alubj 172 4 antiviral antiviral JJ cord-334550-xb0alubj 172 5 activity activity NN cord-334550-xb0alubj 172 6 against against IN cord-334550-xb0alubj 172 7 a a DT cord-334550-xb0alubj 172 8 wide wide JJ cord-334550-xb0alubj 172 9 range range NN cord-334550-xb0alubj 172 10 of of IN cord-334550-xb0alubj 172 11 viruses virus NNS cord-334550-xb0alubj 172 12 including include VBG cord-334550-xb0alubj 172 13 Human Human NNP cord-334550-xb0alubj 172 14 Immunodeficiency Immunodeficiency NNP cord-334550-xb0alubj 172 15 Virus Virus NNP cord-334550-xb0alubj 172 16 1 1 CD cord-334550-xb0alubj 172 17 and and CC cord-334550-xb0alubj 172 18 2 2 CD cord-334550-xb0alubj 172 19 , , , cord-334550-xb0alubj 172 20 Influenza Influenza NNP cord-334550-xb0alubj 172 21 Virus Virus NNP cord-334550-xb0alubj 172 22 ( ( -LRB- cord-334550-xb0alubj 172 23 H1N1 H1N1 NNP cord-334550-xb0alubj 172 24 , , , cord-334550-xb0alubj 172 25 PR8 PR8 NNP cord-334550-xb0alubj 172 26 , , , cord-334550-xb0alubj 172 27 and and CC cord-334550-xb0alubj 172 28 H8N1 H8N1 NNP cord-334550-xb0alubj 172 29 ) ) -RRB- cord-334550-xb0alubj 172 30 , , , cord-334550-xb0alubj 172 31 Herpes Herpes NNP cord-334550-xb0alubj 172 32 Simplex Simplex NNP cord-334550-xb0alubj 172 33 Virus Virus NNP cord-334550-xb0alubj 172 34 ( ( -LRB- cord-334550-xb0alubj 172 35 HSV HSV NNP cord-334550-xb0alubj 172 36 ) ) -RRB- cord-334550-xb0alubj 172 37 1 1 CD cord-334550-xb0alubj 172 38 and and CC cord-334550-xb0alubj 172 39 2 2 CD cord-334550-xb0alubj 172 40 , , , cord-334550-xb0alubj 172 41 Coxsackievirus Coxsackievirus NNP cord-334550-xb0alubj 172 42 , , , cord-334550-xb0alubj 172 43 Hepatitis Hepatitis NNP cord-334550-xb0alubj 172 44 B B NNP cord-334550-xb0alubj 172 45 and and CC cord-334550-xb0alubj 172 46 C c NN cord-334550-xb0alubj 172 47 viruses virus NNS cord-334550-xb0alubj 172 48 , , , cord-334550-xb0alubj 172 49 Human Human NNP cord-334550-xb0alubj 172 50 Papillomavirus Papillomavirus NNP cord-334550-xb0alubj 172 51 ( ( -LRB- cord-334550-xb0alubj 172 52 HPV HPV NNP cord-334550-xb0alubj 172 53 ) ) -RRB- cord-334550-xb0alubj 172 54 types type VBZ cord-334550-xb0alubj 172 55 16 16 CD cord-334550-xb0alubj 172 56 and and CC cord-334550-xb0alubj 172 57 18 18 CD cord-334550-xb0alubj 172 58 , , , cord-334550-xb0alubj 172 59 Japanese Japanese NNP cord-334550-xb0alubj 172 60 Encephalitis Encephalitis NNP cord-334550-xb0alubj 172 61 virus virus NN cord-334550-xb0alubj 172 62 , , , cord-334550-xb0alubj 172 63 and and CC cord-334550-xb0alubj 172 64 Human Human NNP cord-334550-xb0alubj 172 65 T T NNP cord-334550-xb0alubj 172 66 cell cell NN cord-334550-xb0alubj 172 67 Lymphotropic Lymphotropic NNP cord-334550-xb0alubj 172 68 Virus Virus NNP cord-334550-xb0alubj 172 69 type type NN cord-334550-xb0alubj 172 70 1 1 CD cord-334550-xb0alubj 173 1 ( ( -LRB- cord-334550-xb0alubj 173 2 Moghadamtousi Moghadamtousi NNP cord-334550-xb0alubj 173 3 et et NNP cord-334550-xb0alubj 173 4 al al NNP cord-334550-xb0alubj 173 5 . . NNP cord-334550-xb0alubj 173 6 , , , cord-334550-xb0alubj 173 7 2014 2014 CD cord-334550-xb0alubj 173 8 ) ) -RRB- cord-334550-xb0alubj 173 9 . . . cord-334550-xb0alubj 174 1 Similarly similarly RB cord-334550-xb0alubj 174 2 , , , cord-334550-xb0alubj 174 3 ginger ginger NN cord-334550-xb0alubj 174 4 , , , cord-334550-xb0alubj 174 5 another another DT cord-334550-xb0alubj 174 6 rhizomatous rhizomatous JJ cord-334550-xb0alubj 174 7 spice spice NN cord-334550-xb0alubj 174 8 used use VBN cord-334550-xb0alubj 174 9 routinely routinely RB cord-334550-xb0alubj 174 10 in in IN cord-334550-xb0alubj 174 11 Indian indian JJ cord-334550-xb0alubj 174 12 foods food NNS cord-334550-xb0alubj 174 13 contains contain VBZ cord-334550-xb0alubj 174 14 several several JJ cord-334550-xb0alubj 174 15 bioactive bioactive JJ cord-334550-xb0alubj 174 16 phenolic phenolic JJ cord-334550-xb0alubj 174 17 and and CC cord-334550-xb0alubj 174 18 terpene terpene NN cord-334550-xb0alubj 174 19 compounds compound NNS cord-334550-xb0alubj 174 20 that that WDT cord-334550-xb0alubj 174 21 have have VBP cord-334550-xb0alubj 174 22 demonstrated demonstrate VBN cord-334550-xb0alubj 174 23 antiviral antiviral JJ cord-334550-xb0alubj 174 24 activity activity NN cord-334550-xb0alubj 174 25 against against IN cord-334550-xb0alubj 174 26 human human JJ cord-334550-xb0alubj 174 27 respiratory respiratory JJ cord-334550-xb0alubj 174 28 syncytial syncytial JJ cord-334550-xb0alubj 174 29 virus virus NN cord-334550-xb0alubj 174 30 ( ( -LRB- cord-334550-xb0alubj 174 31 blocks block VBZ cord-334550-xb0alubj 174 32 viral viral JJ cord-334550-xb0alubj 174 33 attachment attachment NN cord-334550-xb0alubj 174 34 and and CC cord-334550-xb0alubj 174 35 internalization internalization NN cord-334550-xb0alubj 174 36 ) ) -RRB- cord-334550-xb0alubj 175 1 ( ( -LRB- cord-334550-xb0alubj 175 2 Mao Mao NNP cord-334550-xb0alubj 175 3 et et NNP cord-334550-xb0alubj 175 4 al al NNP cord-334550-xb0alubj 175 5 . . NNP cord-334550-xb0alubj 175 6 , , , cord-334550-xb0alubj 175 7 2019 2019 CD cord-334550-xb0alubj 175 8 ) ) -RRB- cord-334550-xb0alubj 175 9 . . . cord-334550-xb0alubj 176 1 Garlic Garlic NNP cord-334550-xb0alubj 176 2 ( ( -LRB- cord-334550-xb0alubj 176 3 Allium Allium NNP cord-334550-xb0alubj 176 4 sativum sativum NNP cord-334550-xb0alubj 176 5 ) ) -RRB- cord-334550-xb0alubj 176 6 , , , cord-334550-xb0alubj 176 7 a a DT cord-334550-xb0alubj 176 8 popular popular JJ cord-334550-xb0alubj 176 9 condiment condiment NN cord-334550-xb0alubj 176 10 used use VBN cord-334550-xb0alubj 176 11 in in IN cord-334550-xb0alubj 176 12 Indian indian JJ cord-334550-xb0alubj 176 13 foods food NNS cord-334550-xb0alubj 176 14 , , , cord-334550-xb0alubj 176 15 has have VBZ cord-334550-xb0alubj 176 16 been be VBN cord-334550-xb0alubj 176 17 shown show VBN cord-334550-xb0alubj 176 18 to to TO cord-334550-xb0alubj 176 19 possess possess VB cord-334550-xb0alubj 176 20 antiviral antiviral JJ cord-334550-xb0alubj 176 21 activity activity NN cord-334550-xb0alubj 176 22 against against IN cord-334550-xb0alubj 176 23 HSV-1 HSV-1 NNP cord-334550-xb0alubj 177 1 and and CC cord-334550-xb0alubj 177 2 -2 -2 NNP cord-334550-xb0alubj 177 3 , , , cord-334550-xb0alubj 177 4 Parainfluenza Parainfluenza NNP cord-334550-xb0alubj 177 5 Virus Virus NNP cord-334550-xb0alubj 177 6 type type NN cord-334550-xb0alubj 177 7 3 3 CD cord-334550-xb0alubj 177 8 , , , cord-334550-xb0alubj 177 9 and and CC cord-334550-xb0alubj 177 10 Human Human NNP cord-334550-xb0alubj 177 11 Rhinovirus Rhinovirus NNP cord-334550-xb0alubj 177 12 type type NN cord-334550-xb0alubj 177 13 2 2 CD cord-334550-xb0alubj 178 1 ( ( -LRB- cord-334550-xb0alubj 178 2 Lee Lee NNP cord-334550-xb0alubj 178 3 et et NNP cord-334550-xb0alubj 178 4 al al NNP cord-334550-xb0alubj 178 5 . . NNP cord-334550-xb0alubj 178 6 , , , cord-334550-xb0alubj 178 7 2016 2016 CD cord-334550-xb0alubj 178 8 ) ) -RRB- cord-334550-xb0alubj 178 9 . . . cord-334550-xb0alubj 179 1 Capsaicin capsaicin NN cord-334550-xb0alubj 179 2 , , , cord-334550-xb0alubj 179 3 an an DT cord-334550-xb0alubj 179 4 active active JJ cord-334550-xb0alubj 179 5 component component NN cord-334550-xb0alubj 179 6 of of IN cord-334550-xb0alubj 179 7 chili chili NN cord-334550-xb0alubj 179 8 peppers pepper NNS cord-334550-xb0alubj 179 9 , , , cord-334550-xb0alubj 179 10 acts act VBZ cord-334550-xb0alubj 179 11 as as IN cord-334550-xb0alubj 179 12 an an DT cord-334550-xb0alubj 179 13 agonist agonist NN cord-334550-xb0alubj 179 14 at at IN cord-334550-xb0alubj 179 15 vanilloid vanilloid NNP cord-334550-xb0alubj 179 16 receptor receptor NNP cord-334550-xb0alubj 179 17 1 1 CD cord-334550-xb0alubj 179 18 of of IN cord-334550-xb0alubj 179 19 dendritic dendritic JJ cord-334550-xb0alubj 179 20 cells cell NNS cord-334550-xb0alubj 179 21 and and CC cord-334550-xb0alubj 179 22 enhances enhance VBZ cord-334550-xb0alubj 179 23 the the DT cord-334550-xb0alubj 179 24 antiviral antiviral JJ cord-334550-xb0alubj 179 25 activity activity NN cord-334550-xb0alubj 179 26 of of IN cord-334550-xb0alubj 179 27 CD8 CD8 NNP cord-334550-xb0alubj 179 28 + + CC cord-334550-xb0alubj 179 29 cytotoxic cytotoxic JJ cord-334550-xb0alubj 179 30 T t NN cord-334550-xb0alubj 179 31 - - HYPH cord-334550-xb0alubj 179 32 cells cell NNS cord-334550-xb0alubj 179 33 by by IN cord-334550-xb0alubj 179 34 increasing increase VBG cord-334550-xb0alubj 179 35 MHC MHC NNP cord-334550-xb0alubj 179 36 class class NN cord-334550-xb0alubj 179 37 I i NN cord-334550-xb0alubj 179 38 - - HYPH cord-334550-xb0alubj 179 39 restricted restrict VBN cord-334550-xb0alubj 179 40 viral viral JJ cord-334550-xb0alubj 179 41 antigen antigen NN cord-334550-xb0alubj 179 42 presentation presentation NN cord-334550-xb0alubj 179 43 in in IN cord-334550-xb0alubj 179 44 dendritic dendritic JJ cord-334550-xb0alubj 179 45 cells cell NNS cord-334550-xb0alubj 179 46 ( ( -LRB- cord-334550-xb0alubj 179 47 Weber Weber NNP cord-334550-xb0alubj 179 48 et et NNP cord-334550-xb0alubj 179 49 al al NNP cord-334550-xb0alubj 179 50 . . NNP cord-334550-xb0alubj 179 51 , , , cord-334550-xb0alubj 179 52 1992 1992 CD cord-334550-xb0alubj 179 53 ) ) -RRB- cord-334550-xb0alubj 179 54 . . . cord-334550-xb0alubj 180 1 It -PRON- PRP cord-334550-xb0alubj 180 2 has have VBZ cord-334550-xb0alubj 180 3 been be VBN cord-334550-xb0alubj 180 4 shown show VBN cord-334550-xb0alubj 180 5 to to TO cord-334550-xb0alubj 180 6 inhibit inhibit VB cord-334550-xb0alubj 180 7 influenza influenza NN cord-334550-xb0alubj 180 8 A a DT cord-334550-xb0alubj 180 9 virus virus NN cord-334550-xb0alubj 180 10 replication replication NN cord-334550-xb0alubj 180 11 in in IN cord-334550-xb0alubj 180 12 cell cell NN cord-334550-xb0alubj 180 13 cultures culture NNS cord-334550-xb0alubj 180 14 in in IN cord-334550-xb0alubj 180 15 a a DT cord-334550-xb0alubj 180 16 dose dose NN cord-334550-xb0alubj 180 17 dependent dependent JJ cord-334550-xb0alubj 180 18 manner manner NN cord-334550-xb0alubj 181 1 ( ( -LRB- cord-334550-xb0alubj 181 2 Marois Marois NNP cord-334550-xb0alubj 181 3 et et NNP cord-334550-xb0alubj 181 4 al al NNP cord-334550-xb0alubj 181 5 . . . cord-334550-xb0alubj 182 1 , , , cord-334550-xb0alubj 182 2 2014 2014 CD cord-334550-xb0alubj 182 3 ) ) -RRB- cord-334550-xb0alubj 182 4 . . . cord-334550-xb0alubj 183 1 Even even RB cord-334550-xb0alubj 183 2 , , , cord-334550-xb0alubj 183 3 studies study NNS cord-334550-xb0alubj 183 4 from from IN cord-334550-xb0alubj 183 5 China China NNP cord-334550-xb0alubj 183 6 have have VBP cord-334550-xb0alubj 183 7 highlighted highlight VBN cord-334550-xb0alubj 183 8 the the DT cord-334550-xb0alubj 183 9 possible possible JJ cord-334550-xb0alubj 183 10 therapeutic therapeutic JJ cord-334550-xb0alubj 183 11 role role NN cord-334550-xb0alubj 183 12 of of IN cord-334550-xb0alubj 183 13 traditional traditional JJ cord-334550-xb0alubj 183 14 Chinese chinese JJ cord-334550-xb0alubj 183 15 medicines medicine NNS cord-334550-xb0alubj 183 16 in in IN cord-334550-xb0alubj 183 17 the the DT cord-334550-xb0alubj 183 18 treatment treatment NN cord-334550-xb0alubj 183 19 of of IN cord-334550-xb0alubj 183 20 COVID-19 COVID-19 NNP cord-334550-xb0alubj 183 21 . . . cord-334550-xb0alubj 184 1 Thus thus RB cord-334550-xb0alubj 184 2 , , , cord-334550-xb0alubj 184 3 considering consider VBG cord-334550-xb0alubj 184 4 the the DT cord-334550-xb0alubj 184 5 multi multi JJ cord-334550-xb0alubj 184 6 - - JJ cord-334550-xb0alubj 184 7 pharmacological pharmacological JJ cord-334550-xb0alubj 184 8 activity activity NN cord-334550-xb0alubj 184 9 of of IN cord-334550-xb0alubj 184 10 the the DT cord-334550-xb0alubj 184 11 active active JJ cord-334550-xb0alubj 184 12 components component NNS cord-334550-xb0alubj 184 13 in in IN cord-334550-xb0alubj 184 14 Indian indian JJ cord-334550-xb0alubj 184 15 spices spice NNS cord-334550-xb0alubj 184 16 , , , cord-334550-xb0alubj 184 17 it -PRON- PRP cord-334550-xb0alubj 184 18 is be VBZ cord-334550-xb0alubj 184 19 possible possible JJ cord-334550-xb0alubj 184 20 that that IN cord-334550-xb0alubj 184 21 they -PRON- PRP cord-334550-xb0alubj 184 22 might may MD cord-334550-xb0alubj 184 23 have have VB cord-334550-xb0alubj 184 24 some some DT cord-334550-xb0alubj 184 25 role role NN cord-334550-xb0alubj 184 26 in in IN cord-334550-xb0alubj 184 27 defense defense NN cord-334550-xb0alubj 184 28 against against IN cord-334550-xb0alubj 184 29 SARS SARS NNP cord-334550-xb0alubj 184 30 - - HYPH cord-334550-xb0alubj 184 31 CoV-2 CoV-2 NNP cord-334550-xb0alubj 184 32 . . . cord-334550-xb0alubj 185 1 Third third RB cord-334550-xb0alubj 185 2 , , , cord-334550-xb0alubj 185 3 the the DT cord-334550-xb0alubj 185 4 Indian indian JJ cord-334550-xb0alubj 185 5 population population NN cord-334550-xb0alubj 185 6 possesses possess VBZ cord-334550-xb0alubj 185 7 a a DT cord-334550-xb0alubj 185 8 high high JJ cord-334550-xb0alubj 185 9 genetic genetic JJ cord-334550-xb0alubj 185 10 diversity diversity NN cord-334550-xb0alubj 185 11 in in IN cord-334550-xb0alubj 185 12 the the DT cord-334550-xb0alubj 185 13 immune immune JJ cord-334550-xb0alubj 185 14 response response NN cord-334550-xb0alubj 185 15 genes gene NNS cord-334550-xb0alubj 185 16 , , , cord-334550-xb0alubj 185 17 collectively collectively RB cord-334550-xb0alubj 185 18 referred refer VBD cord-334550-xb0alubj 185 19 to to IN cord-334550-xb0alubj 185 20 as as IN cord-334550-xb0alubj 185 21 human human JJ cord-334550-xb0alubj 185 22 leukocyte leukocyte NN cord-334550-xb0alubj 185 23 antigen antigen NN cord-334550-xb0alubj 185 24 ( ( -LRB- cord-334550-xb0alubj 185 25 HLA HLA NNP cord-334550-xb0alubj 185 26 ) ) -RRB- cord-334550-xb0alubj 185 27 complex complex NN cord-334550-xb0alubj 185 28 , , , cord-334550-xb0alubj 185 29 much much RB cord-334550-xb0alubj 185 30 more more RBR cord-334550-xb0alubj 185 31 extensive extensive JJ cord-334550-xb0alubj 185 32 than than IN cord-334550-xb0alubj 185 33 the the DT cord-334550-xb0alubj 185 34 Caucasian caucasian JJ cord-334550-xb0alubj 185 35 population population NN cord-334550-xb0alubj 185 36 and and CC cord-334550-xb0alubj 185 37 this this DT cord-334550-xb0alubj 185 38 is be VBZ cord-334550-xb0alubj 185 39 attributed attribute VBN cord-334550-xb0alubj 185 40 to to IN cord-334550-xb0alubj 185 41 the the DT cord-334550-xb0alubj 185 42 high high JJ cord-334550-xb0alubj 185 43 microbial microbial JJ cord-334550-xb0alubj 185 44 load load NN cord-334550-xb0alubj 185 45 to to TO cord-334550-xb0alubj 185 46 which which WDT cord-334550-xb0alubj 185 47 the the DT cord-334550-xb0alubj 185 48 Indians Indians NNPS cord-334550-xb0alubj 185 49 are be VBP cord-334550-xb0alubj 185 50 exposed expose VBN cord-334550-xb0alubj 185 51 during during IN cord-334550-xb0alubj 185 52 life life NN cord-334550-xb0alubj 185 53 ( ( -LRB- cord-334550-xb0alubj 185 54 Mehra Mehra NNP cord-334550-xb0alubj 185 55 , , , cord-334550-xb0alubj 185 56 2010 2010 CD cord-334550-xb0alubj 185 57 ) ) -RRB- cord-334550-xb0alubj 185 58 . . . cord-334550-xb0alubj 186 1 The the DT cord-334550-xb0alubj 186 2 HLA HLA NNP cord-334550-xb0alubj 186 3 complex complex NN cord-334550-xb0alubj 186 4 serves serve VBZ cord-334550-xb0alubj 186 5 to to TO cord-334550-xb0alubj 186 6 induce induce VB cord-334550-xb0alubj 186 7 and and CC cord-334550-xb0alubj 186 8 regulate regulate VB cord-334550-xb0alubj 186 9 immune immune JJ cord-334550-xb0alubj 186 10 responses response NNS cord-334550-xb0alubj 186 11 . . . cord-334550-xb0alubj 187 1 It -PRON- PRP cord-334550-xb0alubj 187 2 helps help VBZ cord-334550-xb0alubj 187 3 in in IN cord-334550-xb0alubj 187 4 distinguishing distinguish VBG cord-334550-xb0alubj 187 5 self self NN cord-334550-xb0alubj 187 6 antigens antigen NNS cord-334550-xb0alubj 187 7 from from IN cord-334550-xb0alubj 187 8 non non JJ cord-334550-xb0alubj 187 9 - - JJ cord-334550-xb0alubj 187 10 self self JJ cord-334550-xb0alubj 187 11 foreign foreign JJ cord-334550-xb0alubj 187 12 proteins protein NNS cord-334550-xb0alubj 187 13 . . . cord-334550-xb0alubj 188 1 The the DT cord-334550-xb0alubj 188 2 foreign foreign JJ cord-334550-xb0alubj 188 3 antigens antigen NNS cord-334550-xb0alubj 188 4 can can MD cord-334550-xb0alubj 188 5 be be VB cord-334550-xb0alubj 188 6 recognized recognize VBN cord-334550-xb0alubj 188 7 by by IN cord-334550-xb0alubj 188 8 the the DT cord-334550-xb0alubj 188 9 T T NNP cord-334550-xb0alubj 188 10 - - HYPH cord-334550-xb0alubj 188 11 cells cell NNS cord-334550-xb0alubj 188 12 only only RB cord-334550-xb0alubj 188 13 if if IN cord-334550-xb0alubj 188 14 they -PRON- PRP cord-334550-xb0alubj 188 15 are be VBP cord-334550-xb0alubj 188 16 presented present VBN cord-334550-xb0alubj 188 17 in in IN cord-334550-xb0alubj 188 18 association association NN cord-334550-xb0alubj 188 19 with with IN cord-334550-xb0alubj 188 20 HLA HLA NNP cord-334550-xb0alubj 188 21 proteins protein NNS cord-334550-xb0alubj 188 22 . . . cord-334550-xb0alubj 189 1 More more RBR cord-334550-xb0alubj 189 2 the the DT cord-334550-xb0alubj 189 3 number number NN cord-334550-xb0alubj 189 4 of of IN cord-334550-xb0alubj 189 5 HLA HLA NNP cord-334550-xb0alubj 189 6 allotypes allotype NNS cord-334550-xb0alubj 189 7 expressed express VBN cord-334550-xb0alubj 189 8 on on IN cord-334550-xb0alubj 189 9 the the DT cord-334550-xb0alubj 189 10 cell cell NN cord-334550-xb0alubj 189 11 surface surface NN cord-334550-xb0alubj 189 12 , , , cord-334550-xb0alubj 189 13 broader broad JJR cord-334550-xb0alubj 189 14 the the DT cord-334550-xb0alubj 189 15 range range NN cord-334550-xb0alubj 189 16 of of IN cord-334550-xb0alubj 189 17 foreign foreign JJ cord-334550-xb0alubj 189 18 antigens antigen NNS cord-334550-xb0alubj 189 19 they -PRON- PRP cord-334550-xb0alubj 189 20 can can MD cord-334550-xb0alubj 189 21 recognize recognize VB cord-334550-xb0alubj 189 22 and and CC cord-334550-xb0alubj 189 23 present present VB cord-334550-xb0alubj 189 24 to to IN cord-334550-xb0alubj 189 25 the the DT cord-334550-xb0alubj 189 26 T T NNP cord-334550-xb0alubj 189 27 - - HYPH cord-334550-xb0alubj 189 28 cells cell NNS cord-334550-xb0alubj 189 29 . . . cord-334550-xb0alubj 190 1 Thus thus RB cord-334550-xb0alubj 190 2 , , , cord-334550-xb0alubj 190 3 individuals individual NNS cord-334550-xb0alubj 190 4 with with IN cord-334550-xb0alubj 190 5 heterozygous heterozygous JJ cord-334550-xb0alubj 190 6 HLA HLA NNP cord-334550-xb0alubj 190 7 alleles allele NNS cord-334550-xb0alubj 190 8 possess possess VBP cord-334550-xb0alubj 190 9 the the DT cord-334550-xb0alubj 190 10 ability ability NN cord-334550-xb0alubj 190 11 to to TO cord-334550-xb0alubj 190 12 present present VB cord-334550-xb0alubj 190 13 a a DT cord-334550-xb0alubj 190 14 broader broad JJR cord-334550-xb0alubj 190 15 repertoire repertoire NN cord-334550-xb0alubj 190 16 of of IN cord-334550-xb0alubj 190 17 antigenic antigenic JJ cord-334550-xb0alubj 190 18 peptides peptide NNS cord-334550-xb0alubj 190 19 to to IN cord-334550-xb0alubj 190 20 the the DT cord-334550-xb0alubj 190 21 immune immune JJ cord-334550-xb0alubj 190 22 cells cell NNS cord-334550-xb0alubj 190 23 as as IN cord-334550-xb0alubj 190 24 compared compare VBN cord-334550-xb0alubj 190 25 to to IN cord-334550-xb0alubj 190 26 homozygotes homozygote NNS cord-334550-xb0alubj 190 27 ( ( -LRB- cord-334550-xb0alubj 190 28 Mosaad Mosaad NNP cord-334550-xb0alubj 190 29 , , , cord-334550-xb0alubj 190 30 2015 2015 CD cord-334550-xb0alubj 190 31 ) ) -RRB- cord-334550-xb0alubj 190 32 . . . cord-334550-xb0alubj 191 1 According accord VBG cord-334550-xb0alubj 191 2 to to IN cord-334550-xb0alubj 191 3 a a DT cord-334550-xb0alubj 191 4 study study NN cord-334550-xb0alubj 191 5 at at IN cord-334550-xb0alubj 191 6 All all DT cord-334550-xb0alubj 191 7 India India NNP cord-334550-xb0alubj 191 8 Institute Institute NNP cord-334550-xb0alubj 191 9 of of IN cord-334550-xb0alubj 191 10 Medical Medical NNP cord-334550-xb0alubj 191 11 Sciences Sciences NNPS cord-334550-xb0alubj 191 12 , , , cord-334550-xb0alubj 191 13 New New NNP cord-334550-xb0alubj 191 14 Delhi Delhi NNP cord-334550-xb0alubj 191 15 , , , cord-334550-xb0alubj 191 16 India India NNP cord-334550-xb0alubj 191 17 , , , cord-334550-xb0alubj 191 18 several several JJ cord-334550-xb0alubj 191 19 novel novel NN cord-334550-xb0alubj 191 20 HLA HLA NNP cord-334550-xb0alubj 191 21 alleles allele NNS cord-334550-xb0alubj 191 22 ( ( -LRB- cord-334550-xb0alubj 191 23 HLA HLA NNP cord-334550-xb0alubj 191 24 - - HYPH cord-334550-xb0alubj 191 25 A A NNP cord-334550-xb0alubj 191 26 * * NFP cord-334550-xb0alubj 191 27 3303 3303 CD cord-334550-xb0alubj 191 28 ) ) -RRB- cord-334550-xb0alubj 191 29 and and CC cord-334550-xb0alubj 191 30 unique unique JJ cord-334550-xb0alubj 191 31 haplotypes haplotype NNS cord-334550-xb0alubj 191 32 ( ( -LRB- cord-334550-xb0alubj 191 33 HLA HLA NNP cord-334550-xb0alubj 191 34 - - HYPH cord-334550-xb0alubj 191 35 A2-B50-DR3 A2-B50-DR3 NNP cord-334550-xb0alubj 191 36 ) ) -RRB- cord-334550-xb0alubj 191 37 have have VBP cord-334550-xb0alubj 191 38 been be VBN cord-334550-xb0alubj 191 39 observed observe VBN cord-334550-xb0alubj 191 40 in in IN cord-334550-xb0alubj 191 41 the the DT cord-334550-xb0alubj 191 42 Indian indian JJ cord-334550-xb0alubj 191 43 population population NN cord-334550-xb0alubj 191 44 , , , cord-334550-xb0alubj 191 45 which which WDT cord-334550-xb0alubj 191 46 are be VBP cord-334550-xb0alubj 191 47 not not RB cord-334550-xb0alubj 191 48 known know VBN cord-334550-xb0alubj 191 49 to to TO cord-334550-xb0alubj 191 50 occur occur VB cord-334550-xb0alubj 191 51 in in IN cord-334550-xb0alubj 191 52 other other JJ cord-334550-xb0alubj 191 53 ethnic ethnic JJ cord-334550-xb0alubj 191 54 groups group NNS cord-334550-xb0alubj 191 55 ( ( -LRB- cord-334550-xb0alubj 191 56 Mehra Mehra NNP cord-334550-xb0alubj 191 57 , , , cord-334550-xb0alubj 191 58 2010 2010 CD cord-334550-xb0alubj 191 59 ) ) -RRB- cord-334550-xb0alubj 191 60 . . . cord-334550-xb0alubj 192 1 Whether whether IN cord-334550-xb0alubj 192 2 such such JJ cord-334550-xb0alubj 192 3 differences difference NNS cord-334550-xb0alubj 192 4 have have VBP cord-334550-xb0alubj 192 5 any any DT cord-334550-xb0alubj 192 6 influence influence NN cord-334550-xb0alubj 192 7 on on IN cord-334550-xb0alubj 192 8 the the DT cord-334550-xb0alubj 192 9 severity severity NN cord-334550-xb0alubj 192 10 of of IN cord-334550-xb0alubj 192 11 SARS SARS NNP cord-334550-xb0alubj 192 12 - - HYPH cord-334550-xb0alubj 192 13 CoV-2 CoV-2 NNP cord-334550-xb0alubj 192 14 infection infection NN cord-334550-xb0alubj 192 15 need need VBP cord-334550-xb0alubj 192 16 to to TO cord-334550-xb0alubj 192 17 be be VB cord-334550-xb0alubj 192 18 investigated investigate VBN cord-334550-xb0alubj 192 19 . . . cord-334550-xb0alubj 193 1 Recently recently RB cord-334550-xb0alubj 193 2 , , , cord-334550-xb0alubj 193 3 Nguyen Nguyen NNP cord-334550-xb0alubj 193 4 et et NNP cord-334550-xb0alubj 193 5 al al NNP cord-334550-xb0alubj 193 6 . . . cord-334550-xb0alubj 194 1 ( ( -LRB- cord-334550-xb0alubj 194 2 2020 2020 CD cord-334550-xb0alubj 194 3 ) ) -RRB- cord-334550-xb0alubj 194 4 evaluated evaluate VBD cord-334550-xb0alubj 194 5 the the DT cord-334550-xb0alubj 194 6 role role NN cord-334550-xb0alubj 194 7 of of IN cord-334550-xb0alubj 194 8 cross cross JJ cord-334550-xb0alubj 194 9 - - JJ cord-334550-xb0alubj 194 10 protective protective JJ cord-334550-xb0alubj 194 11 immunity immunity NN cord-334550-xb0alubj 194 12 in in IN cord-334550-xb0alubj 194 13 COVID-19 COVID-19 NNP cord-334550-xb0alubj 194 14 and and CC cord-334550-xb0alubj 194 15 reported report VBD cord-334550-xb0alubj 194 16 that that IN cord-334550-xb0alubj 194 17 individuals individual NNS cord-334550-xb0alubj 194 18 with with IN cord-334550-xb0alubj 194 19 HLA HLA NNP cord-334550-xb0alubj 194 20 - - HYPH cord-334550-xb0alubj 194 21 B B NNP cord-334550-xb0alubj 194 22 * * NFP cord-334550-xb0alubj 194 23 46:01 46:01 CD cord-334550-xb0alubj 194 24 allele allele NN cord-334550-xb0alubj 194 25 are be VBP cord-334550-xb0alubj 194 26 particularly particularly RB cord-334550-xb0alubj 194 27 vulnerable vulnerable JJ cord-334550-xb0alubj 194 28 to to IN cord-334550-xb0alubj 194 29 the the DT cord-334550-xb0alubj 194 30 disease disease NN cord-334550-xb0alubj 194 31 due due IN cord-334550-xb0alubj 194 32 to to IN cord-334550-xb0alubj 194 33 expression expression NN cord-334550-xb0alubj 194 34 of of IN cord-334550-xb0alubj 194 35 low low JJ cord-334550-xb0alubj 194 36 levels level NNS cord-334550-xb0alubj 194 37 of of IN cord-334550-xb0alubj 194 38 SARS SARS NNP cord-334550-xb0alubj 194 39 - - HYPH cord-334550-xb0alubj 194 40 CoV-2 CoV-2 NNP cord-334550-xb0alubj 194 41 binding binding NN cord-334550-xb0alubj 194 42 peptides peptide NNS cord-334550-xb0alubj 194 43 , , , cord-334550-xb0alubj 194 44 while while IN cord-334550-xb0alubj 194 45 those those DT cord-334550-xb0alubj 194 46 with with IN cord-334550-xb0alubj 194 47 HLA HLA NNP cord-334550-xb0alubj 194 48 - - HYPH cord-334550-xb0alubj 194 49 B B NNP cord-334550-xb0alubj 194 50 * * NFP cord-334550-xb0alubj 194 51 15:03 15:03 CD cord-334550-xb0alubj 194 52 possess possess VBP cord-334550-xb0alubj 194 53 an an DT cord-334550-xb0alubj 194 54 enhanced enhanced JJ cord-334550-xb0alubj 194 55 capacity capacity NN cord-334550-xb0alubj 194 56 to to TO cord-334550-xb0alubj 194 57 present present VB cord-334550-xb0alubj 194 58 highly highly RB cord-334550-xb0alubj 194 59 conserved conserve VBN cord-334550-xb0alubj 194 60 SARS SARS NNP cord-334550-xb0alubj 194 61 - - HYPH cord-334550-xb0alubj 194 62 CoV-2 CoV-2 NNP cord-334550-xb0alubj 194 63 peptides peptide NNS cord-334550-xb0alubj 194 64 that that WDT cord-334550-xb0alubj 194 65 are be VBP cord-334550-xb0alubj 194 66 shared share VBN cord-334550-xb0alubj 194 67 among among IN cord-334550-xb0alubj 194 68 common common JJ cord-334550-xb0alubj 194 69 human human JJ cord-334550-xb0alubj 194 70 coronaviruses coronaviruse NNS cord-334550-xb0alubj 194 71 , , , cord-334550-xb0alubj 194 72 indicating indicate VBG cord-334550-xb0alubj 194 73 its -PRON- PRP$ cord-334550-xb0alubj 194 74 potential potential NN cord-334550-xb0alubj 194 75 to to TO cord-334550-xb0alubj 194 76 elicit elicit VB cord-334550-xb0alubj 194 77 crossprotective crossprotective JJ cord-334550-xb0alubj 194 78 T t NN cord-334550-xb0alubj 194 79 - - HYPH cord-334550-xb0alubj 194 80 cell cell NN cord-334550-xb0alubj 194 81 based base VBN cord-334550-xb0alubj 194 82 immunity immunity NN cord-334550-xb0alubj 194 83 . . . cord-334550-xb0alubj 195 1 Therefore therefore RB cord-334550-xb0alubj 195 2 , , , cord-334550-xb0alubj 195 3 genetic genetic JJ cord-334550-xb0alubj 195 4 diversity diversity NN cord-334550-xb0alubj 195 5 of of IN cord-334550-xb0alubj 195 6 HLA HLA NNP cord-334550-xb0alubj 195 7 alleles allele NNS cord-334550-xb0alubj 195 8 can can MD cord-334550-xb0alubj 195 9 be be VB cord-334550-xb0alubj 195 10 an an DT cord-334550-xb0alubj 195 11 important important JJ cord-334550-xb0alubj 195 12 factor factor NN cord-334550-xb0alubj 195 13 in in IN cord-334550-xb0alubj 195 14 determining determine VBG cord-334550-xb0alubj 195 15 the the DT cord-334550-xb0alubj 195 16 susceptibility susceptibility NN cord-334550-xb0alubj 195 17 to to IN cord-334550-xb0alubj 195 18 SARS SARS NNP cord-334550-xb0alubj 195 19 - - HYPH cord-334550-xb0alubj 195 20 CoV-2 CoV-2 NNP cord-334550-xb0alubj 195 21 infection infection NN cord-334550-xb0alubj 195 22 . . . cord-334550-xb0alubj 196 1 Fourth fourth JJ cord-334550-xb0alubj 196 2 , , , cord-334550-xb0alubj 196 3 allelic allelic JJ cord-334550-xb0alubj 196 4 variation variation NN cord-334550-xb0alubj 196 5 in in IN cord-334550-xb0alubj 196 6 angiotensin angiotensin NN cord-334550-xb0alubj 196 7 converting convert VBG cord-334550-xb0alubj 196 8 enzyme enzyme NN cord-334550-xb0alubj 196 9 2 2 CD cord-334550-xb0alubj 197 1 ( ( -LRB- cord-334550-xb0alubj 197 2 ACE2 ACE2 NNP cord-334550-xb0alubj 197 3 ) ) -RRB- cord-334550-xb0alubj 197 4 receptor receptor NN cord-334550-xb0alubj 197 5 can can MD cord-334550-xb0alubj 197 6 be be VB cord-334550-xb0alubj 197 7 an an DT cord-334550-xb0alubj 197 8 important important JJ cord-334550-xb0alubj 197 9 factor factor NN cord-334550-xb0alubj 197 10 determining determine VBG cord-334550-xb0alubj 197 11 the the DT cord-334550-xb0alubj 197 12 susceptibility susceptibility NN cord-334550-xb0alubj 197 13 to to IN cord-334550-xb0alubj 197 14 SARS SARS NNP cord-334550-xb0alubj 197 15 - - HYPH cord-334550-xb0alubj 197 16 CoV-2 CoV-2 NNP cord-334550-xb0alubj 197 17 infection infection NN cord-334550-xb0alubj 197 18 . . . cord-334550-xb0alubj 198 1 Cell cell NN cord-334550-xb0alubj 198 2 culture culture NN cord-334550-xb0alubj 198 3 assays assay NNS cord-334550-xb0alubj 198 4 and and CC cord-334550-xb0alubj 198 5 molecular molecular JJ cord-334550-xb0alubj 198 6 superimposition superimposition NN cord-334550-xb0alubj 198 7 studies study NNS cord-334550-xb0alubj 198 8 indicate indicate VBP cord-334550-xb0alubj 198 9 that that IN cord-334550-xb0alubj 198 10 SARS SARS NNP cord-334550-xb0alubj 198 11 - - HYPH cord-334550-xb0alubj 198 12 CoV-2 CoV-2 NNP cord-334550-xb0alubj 198 13 spike spike NN cord-334550-xb0alubj 198 14 ( ( -LRB- cord-334550-xb0alubj 198 15 S s NN cord-334550-xb0alubj 198 16 ) ) -RRB- cord-334550-xb0alubj 198 17 protein protein NN cord-334550-xb0alubj 198 18 has have VBZ cord-334550-xb0alubj 198 19 got get VBN cord-334550-xb0alubj 198 20 high high JJ cord-334550-xb0alubj 198 21 affinity affinity NN cord-334550-xb0alubj 198 22 for for IN cord-334550-xb0alubj 198 23 human human JJ cord-334550-xb0alubj 198 24 ACE2 ACE2 NNP cord-334550-xb0alubj 198 25 receptors receptor NNS cord-334550-xb0alubj 198 26 and and CC cord-334550-xb0alubj 198 27 utilizes utilize VBZ cord-334550-xb0alubj 198 28 the the DT cord-334550-xb0alubj 198 29 same same JJ cord-334550-xb0alubj 198 30 for for IN cord-334550-xb0alubj 198 31 gaining gain VBG cord-334550-xb0alubj 198 32 entry entry NN cord-334550-xb0alubj 198 33 into into IN cord-334550-xb0alubj 198 34 the the DT cord-334550-xb0alubj 198 35 target target NN cord-334550-xb0alubj 198 36 cells cell NNS cord-334550-xb0alubj 198 37 . . . cord-334550-xb0alubj 199 1 ACE2 ACE2 NNP cord-334550-xb0alubj 199 2 receptors receptor NNS cord-334550-xb0alubj 199 3 are be VBP cord-334550-xb0alubj 199 4 widely widely RB cord-334550-xb0alubj 199 5 distributed distribute VBN cord-334550-xb0alubj 199 6 in in IN cord-334550-xb0alubj 199 7 body body NN cord-334550-xb0alubj 199 8 tissues tissue NNS cord-334550-xb0alubj 199 9 , , , cord-334550-xb0alubj 199 10 the the DT cord-334550-xb0alubj 199 11 highest high JJS cord-334550-xb0alubj 199 12 expression expression NN cord-334550-xb0alubj 199 13 being be VBG cord-334550-xb0alubj 199 14 observed observe VBN cord-334550-xb0alubj 199 15 in in IN cord-334550-xb0alubj 199 16 type type NN cord-334550-xb0alubj 199 17 II ii CD cord-334550-xb0alubj 199 18 alveolar alveolar NN cord-334550-xb0alubj 199 19 epithelial epithelial JJ cord-334550-xb0alubj 199 20 cells cell NNS cord-334550-xb0alubj 199 21 ( ( -LRB- cord-334550-xb0alubj 199 22 Hussain Hussain NNP cord-334550-xb0alubj 199 23 et et NNP cord-334550-xb0alubj 199 24 al al NNP cord-334550-xb0alubj 199 25 . . NNP cord-334550-xb0alubj 199 26 , , , cord-334550-xb0alubj 199 27 2020 2020 CD cord-334550-xb0alubj 199 28 ) ) -RRB- cord-334550-xb0alubj 199 29 . . . cord-334550-xb0alubj 200 1 Recent recent JJ cord-334550-xb0alubj 200 2 studies study NNS cord-334550-xb0alubj 200 3 suggest suggest VBP cord-334550-xb0alubj 200 4 a a DT cord-334550-xb0alubj 200 5 correlation correlation NN cord-334550-xb0alubj 200 6 between between IN cord-334550-xb0alubj 200 7 the the DT cord-334550-xb0alubj 200 8 level level NN cord-334550-xb0alubj 200 9 of of IN cord-334550-xb0alubj 200 10 ACE2 ACE2 NNP cord-334550-xb0alubj 200 11 expression expression NN cord-334550-xb0alubj 200 12 on on IN cord-334550-xb0alubj 200 13 cell cell NN cord-334550-xb0alubj 200 14 membrane membrane NN cord-334550-xb0alubj 200 15 and and CC cord-334550-xb0alubj 200 16 viral viral JJ cord-334550-xb0alubj 200 17 infectivity infectivity NN cord-334550-xb0alubj 200 18 , , , cord-334550-xb0alubj 200 19 which which WDT cord-334550-xb0alubj 200 20 in in IN cord-334550-xb0alubj 200 21 turn turn NN cord-334550-xb0alubj 200 22 governs govern VBZ cord-334550-xb0alubj 200 23 disease disease NN cord-334550-xb0alubj 200 24 severity severity NN cord-334550-xb0alubj 200 25 and and CC cord-334550-xb0alubj 200 26 clinical clinical JJ cord-334550-xb0alubj 200 27 outcomes outcome NNS cord-334550-xb0alubj 201 1 ( ( -LRB- cord-334550-xb0alubj 201 2 Jia Jia NNP cord-334550-xb0alubj 201 3 et et NNP cord-334550-xb0alubj 201 4 al al NNP cord-334550-xb0alubj 201 5 . . NNP cord-334550-xb0alubj 201 6 , , , cord-334550-xb0alubj 201 7 2005 2005 CD cord-334550-xb0alubj 201 8 ) ) -RRB- cord-334550-xb0alubj 201 9 . . . cord-334550-xb0alubj 202 1 Hussain Hussain NNP cord-334550-xb0alubj 202 2 et et NNP cord-334550-xb0alubj 202 3 al al NNP cord-334550-xb0alubj 202 4 . . . cord-334550-xb0alubj 203 1 ( ( -LRB- cord-334550-xb0alubj 203 2 2020 2020 CD cord-334550-xb0alubj 203 3 ) ) -RRB- cord-334550-xb0alubj 203 4 reported report VBD cord-334550-xb0alubj 203 5 that that IN cord-334550-xb0alubj 203 6 certain certain JJ cord-334550-xb0alubj 203 7 allelic allelic JJ cord-334550-xb0alubj 203 8 variants variant NNS cord-334550-xb0alubj 203 9 of of IN cord-334550-xb0alubj 203 10 ACE2 ACE2 NNP cord-334550-xb0alubj 203 11 ( ( -LRB- cord-334550-xb0alubj 203 12 S19P s19p NN cord-334550-xb0alubj 203 13 and and CC cord-334550-xb0alubj 203 14 E329 E329 NNP cord-334550-xb0alubj 203 15 G G NNP cord-334550-xb0alubj 203 16 ) ) -RRB- cord-334550-xb0alubj 203 17 demonstrates demonstrate VBZ cord-334550-xb0alubj 203 18 low low JJ cord-334550-xb0alubj 203 19 binding bind VBG cord-334550-xb0alubj 203 20 affinity affinity NN cord-334550-xb0alubj 203 21 for for IN cord-334550-xb0alubj 203 22 the the DT cord-334550-xb0alubj 203 23 viral viral JJ cord-334550-xb0alubj 203 24 spike spike NN cord-334550-xb0alubj 203 25 protein protein NN cord-334550-xb0alubj 203 26 and and CC cord-334550-xb0alubj 203 27 may may MD cord-334550-xb0alubj 203 28 thus thus RB cord-334550-xb0alubj 203 29 confer confer VB cord-334550-xb0alubj 203 30 resistance resistance NN cord-334550-xb0alubj 203 31 to to IN cord-334550-xb0alubj 203 32 SARS SARS NNP cord-334550-xb0alubj 203 33 - - HYPH cord-334550-xb0alubj 203 34 CoV-2 CoV-2 NNP cord-334550-xb0alubj 203 35 infection infection NN cord-334550-xb0alubj 203 36 . . . cord-334550-xb0alubj 204 1 A a DT cord-334550-xb0alubj 204 2 study study NN cord-334550-xb0alubj 204 3 by by IN cord-334550-xb0alubj 204 4 Calcagnile Calcagnile NNP cord-334550-xb0alubj 204 5 et et NNP cord-334550-xb0alubj 204 6 al al NNP cord-334550-xb0alubj 204 7 . . . cord-334550-xb0alubj 205 1 ( ( -LRB- cord-334550-xb0alubj 205 2 2020 2020 CD cord-334550-xb0alubj 205 3 ) ) -RRB- cord-334550-xb0alubj 205 4 found find VBD cord-334550-xb0alubj 205 5 that that IN cord-334550-xb0alubj 205 6 two two CD cord-334550-xb0alubj 205 7 SNPs SNPs NNPS cord-334550-xb0alubj 205 8 - - HYPH cord-334550-xb0alubj 205 9 S19P S19P NNP cord-334550-xb0alubj 205 10 ( ( -LRB- cord-334550-xb0alubj 205 11 common common JJ cord-334550-xb0alubj 205 12 in in IN cord-334550-xb0alubj 205 13 Africans Africans NNPS cord-334550-xb0alubj 205 14 ) ) -RRB- cord-334550-xb0alubj 205 15 and and CC cord-334550-xb0alubj 205 16 K26R K26R VBN cord-334550-xb0alubj 205 17 ( ( -LRB- cord-334550-xb0alubj 205 18 common common JJ cord-334550-xb0alubj 205 19 in in IN cord-334550-xb0alubj 205 20 Europeans Europeans NNPS cord-334550-xb0alubj 205 21 ) ) -RRB- cord-334550-xb0alubj 205 22 can can MD cord-334550-xb0alubj 205 23 potentially potentially RB cord-334550-xb0alubj 205 24 affect affect VB cord-334550-xb0alubj 205 25 the the DT cord-334550-xb0alubj 205 26 interaction interaction NN cord-334550-xb0alubj 205 27 between between IN cord-334550-xb0alubj 205 28 ACE2 ACE2 NNP cord-334550-xb0alubj 205 29 and and CC cord-334550-xb0alubj 205 30 SARS SARS NNP cord-334550-xb0alubj 205 31 - - HYPH cord-334550-xb0alubj 205 32 CoV-2 CoV-2 NNP cord-334550-xb0alubj 205 33 spike spike NN cord-334550-xb0alubj 205 34 glycoprotein glycoprotein NN cord-334550-xb0alubj 205 35 . . . cord-334550-xb0alubj 206 1 While while IN cord-334550-xb0alubj 206 2 the the DT cord-334550-xb0alubj 206 3 former former JJ cord-334550-xb0alubj 206 4 decreases decrease VBZ cord-334550-xb0alubj 206 5 ACE2 ACE2 NNP cord-334550-xb0alubj 206 6 affinity affinity NN cord-334550-xb0alubj 206 7 for for IN cord-334550-xb0alubj 206 8 the the DT cord-334550-xb0alubj 206 9 spike spike NN cord-334550-xb0alubj 206 10 protein protein NN cord-334550-xb0alubj 206 11 and and CC cord-334550-xb0alubj 206 12 lowers lower VBZ cord-334550-xb0alubj 206 13 the the DT cord-334550-xb0alubj 206 14 susceptibility susceptibility NN cord-334550-xb0alubj 206 15 , , , cord-334550-xb0alubj 206 16 the the DT cord-334550-xb0alubj 206 17 latter latter JJ cord-334550-xb0alubj 206 18 increases increase VBZ cord-334550-xb0alubj 206 19 the the DT cord-334550-xb0alubj 206 20 receptor receptor NN cord-334550-xb0alubj 206 21 affinity affinity NN cord-334550-xb0alubj 206 22 and and CC cord-334550-xb0alubj 206 23 predisposes predispose VBZ cord-334550-xb0alubj 206 24 to to IN cord-334550-xb0alubj 206 25 more more RBR cord-334550-xb0alubj 206 26 severe severe JJ cord-334550-xb0alubj 206 27 disease disease NN cord-334550-xb0alubj 206 28 . . . cord-334550-xb0alubj 207 1 Hence hence RB cord-334550-xb0alubj 207 2 , , , cord-334550-xb0alubj 207 3 genetic genetic JJ cord-334550-xb0alubj 207 4 polymorphisms polymorphism NNS cord-334550-xb0alubj 207 5 of of IN cord-334550-xb0alubj 207 6 ACE2 ACE2 NNP cord-334550-xb0alubj 207 7 receptors receptor NNS cord-334550-xb0alubj 207 8 might may MD cord-334550-xb0alubj 207 9 be be VB cord-334550-xb0alubj 207 10 an an DT cord-334550-xb0alubj 207 11 important important JJ cord-334550-xb0alubj 207 12 factor factor NN cord-334550-xb0alubj 207 13 in in IN cord-334550-xb0alubj 207 14 determining determine VBG cord-334550-xb0alubj 207 15 the the DT cord-334550-xb0alubj 207 16 susceptibility susceptibility NN cord-334550-xb0alubj 207 17 to to IN cord-334550-xb0alubj 207 18 SARS SARS NNP cord-334550-xb0alubj 207 19 - - HYPH cord-334550-xb0alubj 207 20 CoV-2 CoV-2 NNP cord-334550-xb0alubj 207 21 . . . cord-334550-xb0alubj 208 1 Fifth fifth JJ cord-334550-xb0alubj 208 2 , , , cord-334550-xb0alubj 208 3 the the DT cord-334550-xb0alubj 208 4 microRNAs microRNAs NNPS cord-334550-xb0alubj 208 5 ( ( -LRB- cord-334550-xb0alubj 208 6 miRNAs miRNAs NNP cord-334550-xb0alubj 208 7 ) ) -RRB- cord-334550-xb0alubj 208 8 might may MD cord-334550-xb0alubj 208 9 play play VB cord-334550-xb0alubj 208 10 a a DT cord-334550-xb0alubj 208 11 crucial crucial JJ cord-334550-xb0alubj 208 12 role role NN cord-334550-xb0alubj 208 13 in in IN cord-334550-xb0alubj 208 14 defense defense NN cord-334550-xb0alubj 208 15 against against IN cord-334550-xb0alubj 208 16 SARS SARS NNP cord-334550-xb0alubj 208 17 - - HYPH cord-334550-xb0alubj 208 18 CoV-2 CoV-2 NNP cord-334550-xb0alubj 208 19 . . . cord-334550-xb0alubj 209 1 miRNAs miRNAs NNP cord-334550-xb0alubj 209 2 are be VBP cord-334550-xb0alubj 209 3 small small JJ cord-334550-xb0alubj 209 4 non non JJ cord-334550-xb0alubj 209 5 - - JJ cord-334550-xb0alubj 209 6 coding coding JJ cord-334550-xb0alubj 209 7 RNAs rna NNS cord-334550-xb0alubj 209 8 that that WDT cord-334550-xb0alubj 209 9 are be VBP cord-334550-xb0alubj 209 10 thought think VBN cord-334550-xb0alubj 209 11 to to TO cord-334550-xb0alubj 209 12 regulate regulate VB cord-334550-xb0alubj 209 13 gene gene NN cord-334550-xb0alubj 209 14 expression expression NN cord-334550-xb0alubj 209 15 and and CC cord-334550-xb0alubj 209 16 cell cell NN cord-334550-xb0alubj 209 17 differentiation differentiation NN cord-334550-xb0alubj 209 18 , , , cord-334550-xb0alubj 209 19 and and CC cord-334550-xb0alubj 209 20 have have VBP cord-334550-xb0alubj 209 21 the the DT cord-334550-xb0alubj 209 22 ability ability NN cord-334550-xb0alubj 209 23 to to TO cord-334550-xb0alubj 209 24 inhibit inhibit VB cord-334550-xb0alubj 209 25 viral viral JJ cord-334550-xb0alubj 209 26 replication replication NN cord-334550-xb0alubj 209 27 in in IN cord-334550-xb0alubj 209 28 a a DT cord-334550-xb0alubj 209 29 sequence sequence NN cord-334550-xb0alubj 209 30 - - HYPH cord-334550-xb0alubj 209 31 specific specific JJ cord-334550-xb0alubj 209 32 manner manner NN cord-334550-xb0alubj 209 33 . . . cord-334550-xb0alubj 210 1 Considering consider VBG cord-334550-xb0alubj 210 2 their -PRON- PRP$ cord-334550-xb0alubj 210 3 unique unique JJ cord-334550-xb0alubj 210 4 mechanism mechanism NN cord-334550-xb0alubj 210 5 of of IN cord-334550-xb0alubj 210 6 action action NN cord-334550-xb0alubj 210 7 , , , cord-334550-xb0alubj 210 8 miRNAs miRNAs NNP cord-334550-xb0alubj 210 9 have have VBP cord-334550-xb0alubj 210 10 become become VBN cord-334550-xb0alubj 210 11 attractive attractive JJ cord-334550-xb0alubj 210 12 candidates candidate NNS cord-334550-xb0alubj 210 13 as as IN cord-334550-xb0alubj 210 14 diagnostic diagnostic JJ cord-334550-xb0alubj 210 15 biomarkers biomarker NNS cord-334550-xb0alubj 210 16 and and CC cord-334550-xb0alubj 210 17 therapeutic therapeutic JJ cord-334550-xb0alubj 210 18 targets target NNS cord-334550-xb0alubj 211 1 ( ( -LRB- cord-334550-xb0alubj 211 2 Correia Correia NNP cord-334550-xb0alubj 211 3 et et NNP cord-334550-xb0alubj 211 4 al al NNP cord-334550-xb0alubj 211 5 . . NNP cord-334550-xb0alubj 211 6 , , , cord-334550-xb0alubj 211 7 2017 2017 CD cord-334550-xb0alubj 211 8 ) ) -RRB- cord-334550-xb0alubj 211 9 . . . cord-334550-xb0alubj 212 1 Several several JJ cord-334550-xb0alubj 212 2 studies study NNS cord-334550-xb0alubj 212 3 have have VBP cord-334550-xb0alubj 212 4 highlighted highlight VBN cord-334550-xb0alubj 212 5 the the DT cord-334550-xb0alubj 212 6 potential potential JJ cord-334550-xb0alubj 212 7 role role NN cord-334550-xb0alubj 212 8 of of IN cord-334550-xb0alubj 212 9 miRNAs miRNAs NNP cord-334550-xb0alubj 212 10 in in IN cord-334550-xb0alubj 212 11 the the DT cord-334550-xb0alubj 212 12 regulation regulation NN cord-334550-xb0alubj 212 13 of of IN cord-334550-xb0alubj 212 14 antiviral antiviral JJ cord-334550-xb0alubj 212 15 defense defense NN cord-334550-xb0alubj 212 16 against against IN cord-334550-xb0alubj 212 17 H1N1 H1N1 NNP cord-334550-xb0alubj 212 18 influenza influenza NN cord-334550-xb0alubj 212 19 , , , cord-334550-xb0alubj 212 20 HIV-1 HIV-1 NNP cord-334550-xb0alubj 212 21 , , , cord-334550-xb0alubj 212 22 HSV-1 hsv-1 NN cord-334550-xb0alubj 212 23 , , , cord-334550-xb0alubj 212 24 HPV hpv NN cord-334550-xb0alubj 212 25 , , , cord-334550-xb0alubj 212 26 enterovirus-71 enterovirus-71 NN cord-334550-xb0alubj 212 27 , , , cord-334550-xb0alubj 212 28 hepatitis hepatitis NN cord-334550-xb0alubj 212 29 B B NNP cord-334550-xb0alubj 212 30 and and CC cord-334550-xb0alubj 212 31 C C NNP cord-334550-xb0alubj 212 32 , , , cord-334550-xb0alubj 212 33 and and CC cord-334550-xb0alubj 212 34 dengue dengue NN cord-334550-xb0alubj 212 35 viruses virus NNS cord-334550-xb0alubj 212 36 ( ( -LRB- cord-334550-xb0alubj 212 37 Barbu Barbu NNP cord-334550-xb0alubj 212 38 et et NNP cord-334550-xb0alubj 212 39 al al NNP cord-334550-xb0alubj 212 40 . . NNP cord-334550-xb0alubj 212 41 , , , cord-334550-xb0alubj 212 42 2020 2020 CD cord-334550-xb0alubj 212 43 ) ) -RRB- cord-334550-xb0alubj 212 44 . . . cord-334550-xb0alubj 213 1 A a DT cord-334550-xb0alubj 213 2 recent recent JJ cord-334550-xb0alubj 213 3 study study NN cord-334550-xb0alubj 213 4 by by IN cord-334550-xb0alubj 213 5 Translational Translational NNP cord-334550-xb0alubj 213 6 Bioinformatics Bioinformatics NNP cord-334550-xb0alubj 213 7 Group Group NNP cord-334550-xb0alubj 213 8 at at IN cord-334550-xb0alubj 213 9 ICGEB ICGEB NNP cord-334550-xb0alubj 213 10 and and CC cord-334550-xb0alubj 213 11 Department Department NNP cord-334550-xb0alubj 213 12 of of IN cord-334550-xb0alubj 213 13 Biochemistry Biochemistry NNP cord-334550-xb0alubj 213 14 , , , cord-334550-xb0alubj 213 15 Jamia Jamia NNP cord-334550-xb0alubj 213 16 Hamdard Hamdard NNP cord-334550-xb0alubj 213 17 , , , cord-334550-xb0alubj 213 18 New New NNP cord-334550-xb0alubj 213 19 Delhi Delhi NNP cord-334550-xb0alubj 213 20 , , , cord-334550-xb0alubj 213 21 India India NNP cord-334550-xb0alubj 213 22 , , , cord-334550-xb0alubj 213 23 revealed reveal VBD cord-334550-xb0alubj 213 24 that that IN cord-334550-xb0alubj 213 25 nine nine CD cord-334550-xb0alubj 213 26 host host NN cord-334550-xb0alubj 213 27 miRNAs miRNAs NNP cord-334550-xb0alubj 213 28 can can MD cord-334550-xb0alubj 213 29 potentially potentially RB cord-334550-xb0alubj 213 30 target target VB cord-334550-xb0alubj 213 31 SARS SARS NNP cord-334550-xb0alubj 213 32 - - HYPH cord-334550-xb0alubj 213 33 CoV-2 CoV-2 NNP cord-334550-xb0alubj 213 34 . . . cord-334550-xb0alubj 214 1 These these DT cord-334550-xb0alubj 214 2 are be VBP cord-334550-xb0alubj 214 3 hsa hsa NNP cord-334550-xb0alubj 214 4 - - HYPH cord-334550-xb0alubj 214 5 let-7a let-7a NNP cord-334550-xb0alubj 214 6 , , , cord-334550-xb0alubj 214 7 hsa hsa NNP cord-334550-xb0alubj 214 8 - - HYPH cord-334550-xb0alubj 214 9 miR101 miR101 NNP cord-334550-xb0alubj 214 10 , , , cord-334550-xb0alubj 214 11 hsa hsa NNP cord-334550-xb0alubj 214 12 - - HYPH cord-334550-xb0alubj 214 13 miR125a-5p miR125a-5p NNP cord-334550-xb0alubj 214 14 , , , cord-334550-xb0alubj 214 15 hsa hsa NNP cord-334550-xb0alubj 214 16 - - HYPH cord-334550-xb0alubj 214 17 miR126 miR126 NNP cord-334550-xb0alubj 214 18 , , , cord-334550-xb0alubj 214 19 hsa hsa NNP cord-334550-xb0alubj 214 20 - - HYPH cord-334550-xb0alubj 214 21 miR222 miR222 NNP cord-334550-xb0alubj 214 22 , , , cord-334550-xb0alubj 214 23 hsa hsa NNP cord-334550-xb0alubj 214 24 - - HYPH cord-334550-xb0alubj 214 25 miR23b miR23b NNP cord-334550-xb0alubj 214 26 , , , cord-334550-xb0alubj 214 27 hsa hsa NNP cord-334550-xb0alubj 214 28 - - HYPH cord-334550-xb0alubj 214 29 miR378 miR378 NNP cord-334550-xb0alubj 214 30 , , , cord-334550-xb0alubj 214 31 hsa hsa NNP cord-334550-xb0alubj 214 32 - - HYPH cord-334550-xb0alubj 214 33 miR380 miR380 NNP cord-334550-xb0alubj 214 34 - - SYM cord-334550-xb0alubj 214 35 5 5 CD cord-334550-xb0alubj 214 36 and and CC cord-334550-xb0alubj 214 37 hsa hsa NNP cord-334550-xb0alubj 214 38 - - HYPH cord-334550-xb0alubj 214 39 miR98 miR98 NNP cord-334550-xb0alubj 214 40 . . . cord-334550-xb0alubj 215 1 Interestingly interestingly RB cord-334550-xb0alubj 215 2 , , , cord-334550-xb0alubj 215 3 a a DT cord-334550-xb0alubj 215 4 single single JJ cord-334550-xb0alubj 215 5 unique unique JJ cord-334550-xb0alubj 215 6 miRNA miRNA NNP cord-334550-xb0alubj 215 7 , , , cord-334550-xb0alubj 215 8 hsa hsa NNP cord-334550-xb0alubj 215 9 - - HYPH cord-334550-xb0alubj 215 10 miR-27b miR-27b NNP cord-334550-xb0alubj 215 11 , , , cord-334550-xb0alubj 215 12 has have VBZ cord-334550-xb0alubj 215 13 been be VBN cord-334550-xb0alubj 215 14 found find VBN cord-334550-xb0alubj 215 15 to to TO cord-334550-xb0alubj 215 16 be be VB cord-334550-xb0alubj 215 17 specifically specifically RB cord-334550-xb0alubj 215 18 targeting target VBG cord-334550-xb0alubj 215 19 the the DT cord-334550-xb0alubj 215 20 Indian indian JJ cord-334550-xb0alubj 215 21 SARS SARS NNP cord-334550-xb0alubj 215 22 - - HYPH cord-334550-xb0alubj 215 23 CoV-2 CoV-2 NNP cord-334550-xb0alubj 215 24 genome genome NN cord-334550-xb0alubj 215 25 , , , cord-334550-xb0alubj 215 26 which which WDT cord-334550-xb0alubj 215 27 has have VBZ cord-334550-xb0alubj 215 28 not not RB cord-334550-xb0alubj 215 29 been be VBN cord-334550-xb0alubj 215 30 detected detect VBN cord-334550-xb0alubj 215 31 elsewhere elsewhere RB cord-334550-xb0alubj 215 32 . . . cord-334550-xb0alubj 216 1 It -PRON- PRP cord-334550-xb0alubj 216 2 has have VBZ cord-334550-xb0alubj 216 3 been be VBN cord-334550-xb0alubj 216 4 hypothesized hypothesize VBN cord-334550-xb0alubj 216 5 that that IN cord-334550-xb0alubj 216 6 hsa hsa NNP cord-334550-xb0alubj 216 7 - - HYPH cord-334550-xb0alubj 216 8 miR-27b miR-27b NNP cord-334550-xb0alubj 216 9 has have VBZ cord-334550-xb0alubj 216 10 a a DT cord-334550-xb0alubj 216 11 specific specific JJ cord-334550-xb0alubj 216 12 role role NN cord-334550-xb0alubj 216 13 in in IN cord-334550-xb0alubj 216 14 defense defense NN cord-334550-xb0alubj 216 15 against against IN cord-334550-xb0alubj 216 16 SARS SARS NNP cord-334550-xb0alubj 216 17 - - HYPH cord-334550-xb0alubj 216 18 CoV-2 CoV-2 NNP cord-334550-xb0alubj 216 19 in in IN cord-334550-xb0alubj 216 20 Indian indian JJ cord-334550-xb0alubj 216 21 population population NN cord-334550-xb0alubj 216 22 that that WDT cord-334550-xb0alubj 216 23 harbors harbor VBZ cord-334550-xb0alubj 216 24 this this DT cord-334550-xb0alubj 216 25 unique unique JJ cord-334550-xb0alubj 216 26 sequence sequence NN cord-334550-xb0alubj 216 27 ( ( -LRB- cord-334550-xb0alubj 216 28 Sardar Sardar NNP cord-334550-xb0alubj 216 29 et et NNP cord-334550-xb0alubj 216 30 al al NNP cord-334550-xb0alubj 216 31 . . NNP cord-334550-xb0alubj 216 32 , , , cord-334550-xb0alubj 216 33 2020 2020 CD cord-334550-xb0alubj 216 34 ) ) -RRB- cord-334550-xb0alubj 216 35 . . . cord-334550-xb0alubj 217 1 These these DT cord-334550-xb0alubj 217 2 findings finding NNS cord-334550-xb0alubj 217 3 indicate indicate VBP cord-334550-xb0alubj 217 4 a a DT cord-334550-xb0alubj 217 5 possible possible JJ cord-334550-xb0alubj 217 6 link link NN cord-334550-xb0alubj 217 7 between between IN cord-334550-xb0alubj 217 8 host host NN cord-334550-xb0alubj 217 9 miRNAs miRNAs NNP cord-334550-xb0alubj 217 10 and and CC cord-334550-xb0alubj 217 11 the the DT cord-334550-xb0alubj 217 12 disease disease NN cord-334550-xb0alubj 217 13 severity severity NN cord-334550-xb0alubj 217 14 as as RB cord-334550-xb0alubj 217 15 well well RB cord-334550-xb0alubj 217 16 as as IN cord-334550-xb0alubj 217 17 treatment treatment NN cord-334550-xb0alubj 217 18 outcomes outcome NNS cord-334550-xb0alubj 217 19 . . . cord-334550-xb0alubj 218 1 Sixth sixth JJ cord-334550-xb0alubj 218 2 , , , cord-334550-xb0alubj 218 3 the the DT cord-334550-xb0alubj 218 4 Indians Indians NNPS cord-334550-xb0alubj 218 5 have have VBP cord-334550-xb0alubj 218 6 a a DT cord-334550-xb0alubj 218 7 higher high JJR cord-334550-xb0alubj 218 8 percentage percentage NN cord-334550-xb0alubj 218 9 of of IN cord-334550-xb0alubj 218 10 nature nature NN cord-334550-xb0alubj 218 11 killer killer NN cord-334550-xb0alubj 218 12 ( ( -LRB- cord-334550-xb0alubj 218 13 NK NK NNP cord-334550-xb0alubj 218 14 ) ) -RRB- cord-334550-xb0alubj 218 15 cells cell NNS cord-334550-xb0alubj 218 16 , , , cord-334550-xb0alubj 218 17 compared compare VBN cord-334550-xb0alubj 218 18 to to IN cord-334550-xb0alubj 218 19 other other JJ cord-334550-xb0alubj 218 20 ethnic ethnic JJ cord-334550-xb0alubj 218 21 groups group NNS cord-334550-xb0alubj 218 22 ( ( -LRB- cord-334550-xb0alubj 218 23 Rathore Rathore NNP cord-334550-xb0alubj 218 24 et et FW cord-334550-xb0alubj 218 25 al al NNP cord-334550-xb0alubj 218 26 . . NNP cord-334550-xb0alubj 218 27 , , , cord-334550-xb0alubj 218 28 2018 2018 CD cord-334550-xb0alubj 218 29 ) ) -RRB- cord-334550-xb0alubj 218 30 . . . cord-334550-xb0alubj 219 1 It -PRON- PRP cord-334550-xb0alubj 219 2 has have VBZ cord-334550-xb0alubj 219 3 been be VBN cord-334550-xb0alubj 219 4 postulated postulate VBN cord-334550-xb0alubj 219 5 that that IN cord-334550-xb0alubj 219 6 the the DT cord-334550-xb0alubj 219 7 development development NN cord-334550-xb0alubj 219 8 , , , cord-334550-xb0alubj 219 9 tolerance tolerance NN cord-334550-xb0alubj 219 10 and and CC cord-334550-xb0alubj 219 11 activation activation NN cord-334550-xb0alubj 219 12 of of IN cord-334550-xb0alubj 219 13 NK NK NNP cord-334550-xb0alubj 219 14 cells cell NNS cord-334550-xb0alubj 219 15 are be VBP cord-334550-xb0alubj 219 16 regulated regulate VBN cord-334550-xb0alubj 219 17 by by IN cord-334550-xb0alubj 219 18 the the DT cord-334550-xb0alubj 219 19 killer killer NN cord-334550-xb0alubj 219 20 cell cell NN cord-334550-xb0alubj 219 21 immunoglobulin immunoglobulin NN cord-334550-xb0alubj 219 22 - - HYPH cord-334550-xb0alubj 219 23 like like JJ cord-334550-xb0alubj 219 24 receptors receptor NNS cord-334550-xb0alubj 219 25 ( ( -LRB- cord-334550-xb0alubj 219 26 KIR KIR NNP cord-334550-xb0alubj 219 27 ) ) -RRB- cord-334550-xb0alubj 219 28 present present VB cord-334550-xb0alubj 219 29 on on IN cord-334550-xb0alubj 219 30 their -PRON- PRP$ cord-334550-xb0alubj 219 31 surface surface NN cord-334550-xb0alubj 219 32 . . . cord-334550-xb0alubj 220 1 These these DT cord-334550-xb0alubj 220 2 receptors receptor NNS cord-334550-xb0alubj 220 3 interact interact VBP cord-334550-xb0alubj 220 4 with with IN cord-334550-xb0alubj 220 5 HLA HLA NNP cord-334550-xb0alubj 220 6 class class NN cord-334550-xb0alubj 221 1 I -PRON- PRP cord-334550-xb0alubj 221 2 expressed express VBD cord-334550-xb0alubj 221 3 by by IN cord-334550-xb0alubj 221 4 target target NN cord-334550-xb0alubj 221 5 cells cell NNS cord-334550-xb0alubj 221 6 and and CC cord-334550-xb0alubj 221 7 regulate regulate VB cord-334550-xb0alubj 221 8 cytolytic cytolytic JJ cord-334550-xb0alubj 221 9 activity activity NN cord-334550-xb0alubj 221 10 ( ( -LRB- cord-334550-xb0alubj 221 11 Campbell Campbell NNP cord-334550-xb0alubj 221 12 and and CC cord-334550-xb0alubj 221 13 Purdy Purdy NNP cord-334550-xb0alubj 221 14 , , , cord-334550-xb0alubj 221 15 2011 2011 CD cord-334550-xb0alubj 221 16 ) ) -RRB- cord-334550-xb0alubj 221 17 . . . cord-334550-xb0alubj 222 1 While while IN cord-334550-xb0alubj 222 2 most most JJS cord-334550-xb0alubj 222 3 KIRs kir NNS cord-334550-xb0alubj 222 4 are be VBP cord-334550-xb0alubj 222 5 inhibitory inhibitory JJ cord-334550-xb0alubj 222 6 and and CC cord-334550-xb0alubj 222 7 tend tend VBP cord-334550-xb0alubj 222 8 to to TO cord-334550-xb0alubj 222 9 suppress suppress VB cord-334550-xb0alubj 222 10 NK NK NNP cord-334550-xb0alubj 222 11 cell cell NN cord-334550-xb0alubj 222 12 function function NN cord-334550-xb0alubj 222 13 , , , cord-334550-xb0alubj 222 14 activating activate VBG cord-334550-xb0alubj 222 15 receptors receptor NNS cord-334550-xb0alubj 222 16 ( ( -LRB- cord-334550-xb0alubj 222 17 KIR2DS1 kir2ds1 CD cord-334550-xb0alubj 222 18 - - SYM cord-334550-xb0alubj 222 19 5 5 CD cord-334550-xb0alubj 222 20 , , , cord-334550-xb0alubj 222 21 KIR3DS1 kir3ds1 NN cord-334550-xb0alubj 222 22 ) ) -RRB- cord-334550-xb0alubj 222 23 are be VBP cord-334550-xb0alubj 222 24 upregulated upregulate VBN cord-334550-xb0alubj 222 25 in in IN cord-334550-xb0alubj 222 26 viral viral JJ cord-334550-xb0alubj 222 27 infections infection NNS cord-334550-xb0alubj 222 28 and and CC cord-334550-xb0alubj 222 29 host host NN cord-334550-xb0alubj 222 30 cell cell NN cord-334550-xb0alubj 222 31 aberrations aberration NNS cord-334550-xb0alubj 222 32 . . . cord-334550-xb0alubj 223 1 All all DT cord-334550-xb0alubj 223 2 activating activate VBG cord-334550-xb0alubj 223 3 KIRs kir NNS cord-334550-xb0alubj 223 4 ( ( -LRB- cord-334550-xb0alubj 223 5 except except IN cord-334550-xb0alubj 223 6 KIR2DS4 kir2ds4 NN cord-334550-xb0alubj 223 7 ) ) -RRB- cord-334550-xb0alubj 223 8 are be VBP cord-334550-xb0alubj 223 9 encoded encode VBN cord-334550-xb0alubj 223 10 by by IN cord-334550-xb0alubj 223 11 B b NN cord-334550-xb0alubj 223 12 haplotype haplotype NN cord-334550-xb0alubj 223 13 ( ( -LRB- cord-334550-xb0alubj 223 14 Hiby Hiby NNP cord-334550-xb0alubj 223 15 et et FW cord-334550-xb0alubj 223 16 al al NNP cord-334550-xb0alubj 223 17 . . NNP cord-334550-xb0alubj 223 18 , , , cord-334550-xb0alubj 223 19 2010 2010 CD cord-334550-xb0alubj 223 20 ) ) -RRB- cord-334550-xb0alubj 223 21 . . . cord-334550-xb0alubj 224 1 It -PRON- PRP cord-334550-xb0alubj 224 2 has have VBZ cord-334550-xb0alubj 224 3 been be VBN cord-334550-xb0alubj 224 4 observed observe VBN cord-334550-xb0alubj 224 5 that that IN cord-334550-xb0alubj 224 6 B b NN cord-334550-xb0alubj 224 7 haplotypes haplotype NNS cord-334550-xb0alubj 224 8 are be VBP cord-334550-xb0alubj 224 9 more more RBR cord-334550-xb0alubj 224 10 prevalent prevalent JJ cord-334550-xb0alubj 224 11 in in IN cord-334550-xb0alubj 224 12 non non JJ cord-334550-xb0alubj 224 13 - - JJ cord-334550-xb0alubj 224 14 Caucasian caucasian JJ cord-334550-xb0alubj 224 15 populations population NNS cord-334550-xb0alubj 224 16 such such JJ cord-334550-xb0alubj 224 17 as as IN cord-334550-xb0alubj 224 18 Australia Australia NNP cord-334550-xb0alubj 224 19 Aborigines Aborigines NNPS cord-334550-xb0alubj 224 20 and and CC cord-334550-xb0alubj 224 21 Asian Asian NNP cord-334550-xb0alubj 224 22 Indians Indians NNPS cord-334550-xb0alubj 224 23 than than IN cord-334550-xb0alubj 224 24 in in IN cord-334550-xb0alubj 224 25 Caucasian caucasian JJ cord-334550-xb0alubj 224 26 populations population NNS cord-334550-xb0alubj 224 27 , , , cord-334550-xb0alubj 224 28 and and CC cord-334550-xb0alubj 224 29 such such JJ cord-334550-xb0alubj 224 30 populations population NNS cord-334550-xb0alubj 224 31 are be VBP cord-334550-xb0alubj 224 32 likely likely JJ cord-334550-xb0alubj 224 33 to to TO cord-334550-xb0alubj 224 34 be be VB cord-334550-xb0alubj 224 35 under under IN cord-334550-xb0alubj 224 36 high high JJ cord-334550-xb0alubj 224 37 selection selection NN cord-334550-xb0alubj 224 38 pressure pressure NN cord-334550-xb0alubj 224 39 from from IN cord-334550-xb0alubj 224 40 infectious infectious JJ cord-334550-xb0alubj 224 41 diseases disease NNS cord-334550-xb0alubj 224 42 , , , cord-334550-xb0alubj 224 43 much much RB cord-334550-xb0alubj 224 44 more more JJR cord-334550-xb0alubj 224 45 than than IN cord-334550-xb0alubj 224 46 other other JJ cord-334550-xb0alubj 224 47 ethnic ethnic JJ cord-334550-xb0alubj 224 48 groups group NNS cord-334550-xb0alubj 224 49 . . . cord-334550-xb0alubj 225 1 KIR KIR NNP cord-334550-xb0alubj 225 2 genes gene NNS cord-334550-xb0alubj 225 3 display display VBP cord-334550-xb0alubj 225 4 extraordinary extraordinary JJ cord-334550-xb0alubj 225 5 level level NN cord-334550-xb0alubj 225 6 of of IN cord-334550-xb0alubj 225 7 polymorphism polymorphism NN cord-334550-xb0alubj 225 8 and and CC cord-334550-xb0alubj 225 9 diversity diversity NN cord-334550-xb0alubj 225 10 among among IN cord-334550-xb0alubj 225 11 different different JJ cord-334550-xb0alubj 225 12 populations population NNS cord-334550-xb0alubj 225 13 because because IN cord-334550-xb0alubj 225 14 of of IN cord-334550-xb0alubj 225 15 which which WDT cord-334550-xb0alubj 225 16 there there EX cord-334550-xb0alubj 225 17 may may MD cord-334550-xb0alubj 225 18 be be VB cord-334550-xb0alubj 225 19 significant significant JJ cord-334550-xb0alubj 225 20 differences difference NNS cord-334550-xb0alubj 225 21 in in IN cord-334550-xb0alubj 225 22 ligand ligand NN cord-334550-xb0alubj 225 23 affinity affinity NN cord-334550-xb0alubj 225 24 or or CC cord-334550-xb0alubj 225 25 signal signal NN cord-334550-xb0alubj 225 26 transduction transduction NN cord-334550-xb0alubj 225 27 . . . cord-334550-xb0alubj 226 1 Populationbased populationbased JJ cord-334550-xb0alubj 226 2 analysis analysis NN cord-334550-xb0alubj 226 3 of of IN cord-334550-xb0alubj 226 4 KIR KIR NNP cord-334550-xb0alubj 226 5 genes gene NNS cord-334550-xb0alubj 226 6 reveal reveal VBP cord-334550-xb0alubj 226 7 that that IN cord-334550-xb0alubj 226 8 KIR2DS2 kir2ds2 CD cord-334550-xb0alubj 226 9 , , , cord-334550-xb0alubj 226 10 an an DT cord-334550-xb0alubj 226 11 activating activate VBG cord-334550-xb0alubj 226 12 KIR KIR NNP cord-334550-xb0alubj 226 13 , , , cord-334550-xb0alubj 226 14 has have VBZ cord-334550-xb0alubj 226 15 high high JJ cord-334550-xb0alubj 226 16 frequencies frequency NNS cord-334550-xb0alubj 226 17 ( ( -LRB- cord-334550-xb0alubj 226 18 > > NFP cord-334550-xb0alubj 226 19 70 70 CD cord-334550-xb0alubj 226 20 % % NN cord-334550-xb0alubj 226 21 ) ) -RRB- cord-334550-xb0alubj 226 22 in in IN cord-334550-xb0alubj 226 23 Australia Australia NNP cord-334550-xb0alubj 226 24 aborigines aborigine NNS cord-334550-xb0alubj 226 25 and and CC cord-334550-xb0alubj 226 26 Indian indian JJ cord-334550-xb0alubj 226 27 population population NN cord-334550-xb0alubj 226 28 , , , cord-334550-xb0alubj 226 29 but but CC cord-334550-xb0alubj 226 30 low low JJ cord-334550-xb0alubj 226 31 frequencies frequency NNS cord-334550-xb0alubj 226 32 in in IN cord-334550-xb0alubj 226 33 other other JJ cord-334550-xb0alubj 226 34 ethnic ethnic JJ cord-334550-xb0alubj 226 35 groups group NNS cord-334550-xb0alubj 226 36 ( ( -LRB- cord-334550-xb0alubj 226 37 Middleton Middleton NNP cord-334550-xb0alubj 226 38 and and CC cord-334550-xb0alubj 226 39 Gonzelez Gonzelez NNP cord-334550-xb0alubj 226 40 , , , cord-334550-xb0alubj 226 41 2010 2010 CD cord-334550-xb0alubj 226 42 ) ) -RRB- cord-334550-xb0alubj 226 43 . . . cord-334550-xb0alubj 227 1 According accord VBG cord-334550-xb0alubj 227 2 to to IN cord-334550-xb0alubj 227 3 Rajalingam Rajalingam NNP cord-334550-xb0alubj 227 4 et et NNP cord-334550-xb0alubj 227 5 al al NNP cord-334550-xb0alubj 227 6 . . . cord-334550-xb0alubj 228 1 ( ( -LRB- cord-334550-xb0alubj 228 2 2008 2008 CD cord-334550-xb0alubj 228 3 ) ) -RRB- cord-334550-xb0alubj 228 4 , , , cord-334550-xb0alubj 228 5 the the DT cord-334550-xb0alubj 228 6 Indians Indians NNPS cord-334550-xb0alubj 228 7 might may MD cord-334550-xb0alubj 228 8 have have VB cord-334550-xb0alubj 228 9 acquired acquire VBN cord-334550-xb0alubj 228 10 activating activate VBG cord-334550-xb0alubj 228 11 KIR KIR NNP cord-334550-xb0alubj 228 12 genes gene NNS cord-334550-xb0alubj 228 13 through through IN cord-334550-xb0alubj 228 14 a a DT cord-334550-xb0alubj 228 15 process process NN cord-334550-xb0alubj 228 16 of of IN cord-334550-xb0alubj 228 17 natural natural JJ cord-334550-xb0alubj 228 18 selection selection NN cord-334550-xb0alubj 228 19 that that WDT cord-334550-xb0alubj 228 20 enabled enable VBD cord-334550-xb0alubj 228 21 them -PRON- PRP cord-334550-xb0alubj 228 22 to to TO cord-334550-xb0alubj 228 23 survive survive VB cord-334550-xb0alubj 228 24 epidemics epidemic NNS cord-334550-xb0alubj 228 25 during during IN cord-334550-xb0alubj 228 26 their -PRON- PRP$ cord-334550-xb0alubj 228 27 pre pre JJ cord-334550-xb0alubj 228 28 - - JJ cord-334550-xb0alubj 228 29 historic historic JJ cord-334550-xb0alubj 228 30 migrations migration NNS cord-334550-xb0alubj 228 31 from from IN cord-334550-xb0alubj 228 32 Africa Africa NNP cord-334550-xb0alubj 228 33 . . . cord-334550-xb0alubj 229 1 Thus thus RB cord-334550-xb0alubj 229 2 , , , cord-334550-xb0alubj 229 3 it -PRON- PRP cord-334550-xb0alubj 229 4 is be VBZ cord-334550-xb0alubj 229 5 possible possible JJ cord-334550-xb0alubj 229 6 that that IN cord-334550-xb0alubj 229 7 the the DT cord-334550-xb0alubj 229 8 diversity diversity NN cord-334550-xb0alubj 229 9 in in IN cord-334550-xb0alubj 229 10 KIR KIR NNP cord-334550-xb0alubj 229 11 gene gene NN cord-334550-xb0alubj 229 12 complex complex NN cord-334550-xb0alubj 229 13 occurred occur VBD cord-334550-xb0alubj 229 14 as as IN cord-334550-xb0alubj 229 15 a a DT cord-334550-xb0alubj 229 16 result result NN cord-334550-xb0alubj 229 17 of of IN cord-334550-xb0alubj 229 18 natural natural JJ cord-334550-xb0alubj 229 19 selection selection NN cord-334550-xb0alubj 229 20 by by IN cord-334550-xb0alubj 229 21 pathogens pathogen NNS cord-334550-xb0alubj 229 22 so so IN cord-334550-xb0alubj 229 23 as as IN cord-334550-xb0alubj 229 24 to to TO cord-334550-xb0alubj 229 25 offer offer VB cord-334550-xb0alubj 229 26 a a DT cord-334550-xb0alubj 229 27 survival survival NN cord-334550-xb0alubj 229 28 benefit benefit NN cord-334550-xb0alubj 229 29 . . . cord-334550-xb0alubj 230 1 Such such JJ cord-334550-xb0alubj 230 2 diversification diversification NN cord-334550-xb0alubj 230 3 might may MD cord-334550-xb0alubj 230 4 be be VB cord-334550-xb0alubj 230 5 a a DT cord-334550-xb0alubj 230 6 reason reason NN cord-334550-xb0alubj 230 7 for for IN cord-334550-xb0alubj 230 8 the the DT cord-334550-xb0alubj 230 9 Indian indian JJ cord-334550-xb0alubj 230 10 population population NN cord-334550-xb0alubj 230 11 to to TO cord-334550-xb0alubj 230 12 respond respond VB cord-334550-xb0alubj 230 13 differently differently RB cord-334550-xb0alubj 230 14 to to IN cord-334550-xb0alubj 230 15 SARS SARS NNP cord-334550-xb0alubj 230 16 - - HYPH cord-334550-xb0alubj 230 17 CoV-2 CoV-2 NNP cord-334550-xb0alubj 230 18 . . . cord-334550-xb0alubj 231 1 Seventh seventh JJ cord-334550-xb0alubj 231 2 , , , cord-334550-xb0alubj 231 3 live live VBP cord-334550-xb0alubj 231 4 attenuated attenuated JJ cord-334550-xb0alubj 231 5 vaccines vaccine NNS cord-334550-xb0alubj 231 6 like like IN cord-334550-xb0alubj 231 7 Bacillus Bacillus NNP cord-334550-xb0alubj 231 8 Calmette Calmette NNP cord-334550-xb0alubj 231 9 - - HYPH cord-334550-xb0alubj 231 10 Guérin Guérin NNP cord-334550-xb0alubj 231 11 ( ( -LRB- cord-334550-xb0alubj 231 12 BCG BCG NNP cord-334550-xb0alubj 231 13 ) ) -RRB- cord-334550-xb0alubj 231 14 and and CC cord-334550-xb0alubj 231 15 Mumps Mumps NNP cord-334550-xb0alubj 231 16 , , , cord-334550-xb0alubj 231 17 Measles Measles NNP cord-334550-xb0alubj 231 18 , , , cord-334550-xb0alubj 231 19 Rubella Rubella NNP cord-334550-xb0alubj 231 20 ( ( -LRB- cord-334550-xb0alubj 231 21 MMR MMR NNP cord-334550-xb0alubj 231 22 ) ) -RRB- cord-334550-xb0alubj 231 23 commonly commonly RB cord-334550-xb0alubj 231 24 administered administer VBN cord-334550-xb0alubj 231 25 during during IN cord-334550-xb0alubj 231 26 childhood childhood NN cord-334550-xb0alubj 231 27 , , , cord-334550-xb0alubj 231 28 have have VBP cord-334550-xb0alubj 231 29 been be VBN cord-334550-xb0alubj 231 30 found find VBN cord-334550-xb0alubj 231 31 to to TO cord-334550-xb0alubj 231 32 confer confer VB cord-334550-xb0alubj 231 33 nonspecific nonspecific JJ cord-334550-xb0alubj 231 34 protection protection NN cord-334550-xb0alubj 231 35 against against IN cord-334550-xb0alubj 231 36 unrelated unrelated JJ cord-334550-xb0alubj 231 37 lethal lethal JJ cord-334550-xb0alubj 231 38 infections infection NNS cord-334550-xb0alubj 231 39 by by IN cord-334550-xb0alubj 231 40 inducing induce VBG cord-334550-xb0alubj 231 41 " " `` cord-334550-xb0alubj 231 42 trained trained JJ cord-334550-xb0alubj 231 43 " " '' cord-334550-xb0alubj 231 44 non non JJ cord-334550-xb0alubj 231 45 - - JJ cord-334550-xb0alubj 231 46 specific specific JJ cord-334550-xb0alubj 231 47 innate innate JJ cord-334550-xb0alubj 231 48 immune immune JJ cord-334550-xb0alubj 231 49 cells cell NNS cord-334550-xb0alubj 231 50 for for IN cord-334550-xb0alubj 231 51 more more RBR cord-334550-xb0alubj 231 52 efficient efficient JJ cord-334550-xb0alubj 231 53 host host NN cord-334550-xb0alubj 231 54 response response NN cord-334550-xb0alubj 231 55 against against IN cord-334550-xb0alubj 231 56 wide wide JJ cord-334550-xb0alubj 231 57 range range NN cord-334550-xb0alubj 231 58 of of IN cord-334550-xb0alubj 231 59 pathogens pathogen NNS cord-334550-xb0alubj 231 60 ( ( -LRB- cord-334550-xb0alubj 231 61 Fidel Fidel NNP cord-334550-xb0alubj 231 62 and and CC cord-334550-xb0alubj 231 63 Noverr Noverr NNP cord-334550-xb0alubj 231 64 , , , cord-334550-xb0alubj 231 65 2020 2020 CD cord-334550-xb0alubj 231 66 ) ) -RRB- cord-334550-xb0alubj 231 67 . . . cord-334550-xb0alubj 232 1 The the DT cord-334550-xb0alubj 232 2 BCG BCG NNP cord-334550-xb0alubj 232 3 vaccine vaccine NN cord-334550-xb0alubj 232 4 , , , cord-334550-xb0alubj 232 5 given give VBN cord-334550-xb0alubj 232 6 universally universally RB cord-334550-xb0alubj 232 7 to to IN cord-334550-xb0alubj 232 8 Indian indian JJ cord-334550-xb0alubj 232 9 babies baby NNS cord-334550-xb0alubj 232 10 at at IN cord-334550-xb0alubj 232 11 birth birth NN cord-334550-xb0alubj 232 12 for for IN cord-334550-xb0alubj 232 13 protection protection NN cord-334550-xb0alubj 232 14 against against IN cord-334550-xb0alubj 232 15 tuberculosis tuberculosis NN cord-334550-xb0alubj 232 16 , , , cord-334550-xb0alubj 232 17 might may MD cord-334550-xb0alubj 232 18 confer confer VB cord-334550-xb0alubj 232 19 some some DT cord-334550-xb0alubj 232 20 protection protection NN cord-334550-xb0alubj 232 21 against against IN cord-334550-xb0alubj 232 22 SARS SARS NNP cord-334550-xb0alubj 232 23 - - HYPH cord-334550-xb0alubj 232 24 CoV-2 CoV-2 NNP cord-334550-xb0alubj 232 25 , , , cord-334550-xb0alubj 232 26 possibly possibly RB cord-334550-xb0alubj 232 27 through through IN cord-334550-xb0alubj 232 28 activation activation NN cord-334550-xb0alubj 232 29 of of IN cord-334550-xb0alubj 232 30 T t NN cord-334550-xb0alubj 232 31 - - HYPH cord-334550-xb0alubj 232 32 cell cell NN cord-334550-xb0alubj 232 33 mediated mediate VBN cord-334550-xb0alubj 232 34 immune immune JJ cord-334550-xb0alubj 232 35 response response NN cord-334550-xb0alubj 232 36 . . . cord-334550-xb0alubj 233 1 BCG BCG NNP cord-334550-xb0alubj 233 2 has have VBZ cord-334550-xb0alubj 233 3 no no DT cord-334550-xb0alubj 233 4 direct direct JJ cord-334550-xb0alubj 233 5 antiviral antiviral JJ cord-334550-xb0alubj 233 6 action action NN cord-334550-xb0alubj 233 7 , , , cord-334550-xb0alubj 233 8 but but CC cord-334550-xb0alubj 233 9 it -PRON- PRP cord-334550-xb0alubj 233 10 may may MD cord-334550-xb0alubj 233 11 act act VB cord-334550-xb0alubj 233 12 as as IN cord-334550-xb0alubj 233 13 an an DT cord-334550-xb0alubj 233 14 immunopotentiator immunopotentiator NN cord-334550-xb0alubj 234 1 ( ( -LRB- cord-334550-xb0alubj 234 2 Tsiang Tsiang NNP cord-334550-xb0alubj 234 3 et et NNP cord-334550-xb0alubj 234 4 al al NNP cord-334550-xb0alubj 234 5 . . NNP cord-334550-xb0alubj 234 6 , , , cord-334550-xb0alubj 234 7 1981 1981 CD cord-334550-xb0alubj 234 8 ) ) -RRB- cord-334550-xb0alubj 234 9 . . . cord-334550-xb0alubj 235 1 Studies study NNS cord-334550-xb0alubj 235 2 have have VBP cord-334550-xb0alubj 235 3 demonstrated demonstrate VBN cord-334550-xb0alubj 235 4 the the DT cord-334550-xb0alubj 235 5 ability ability NN cord-334550-xb0alubj 235 6 of of IN cord-334550-xb0alubj 235 7 BCG BCG NNP cord-334550-xb0alubj 235 8 vaccine vaccine NN cord-334550-xb0alubj 235 9 in in IN cord-334550-xb0alubj 235 10 reducing reduce VBG cord-334550-xb0alubj 235 11 viraemia viraemia NN cord-334550-xb0alubj 235 12 associated associate VBN cord-334550-xb0alubj 235 13 with with IN cord-334550-xb0alubj 235 14 yellow yellow JJ cord-334550-xb0alubj 235 15 fever fever NN cord-334550-xb0alubj 235 16 vaccine vaccine NN cord-334550-xb0alubj 235 17 ( ( -LRB- cord-334550-xb0alubj 235 18 Arts art NNS cord-334550-xb0alubj 235 19 et et NNP cord-334550-xb0alubj 235 20 al al NNP cord-334550-xb0alubj 235 21 . . NNP cord-334550-xb0alubj 235 22 , , , cord-334550-xb0alubj 235 23 2018 2018 CD cord-334550-xb0alubj 235 24 ) ) -RRB- cord-334550-xb0alubj 235 25 , , , cord-334550-xb0alubj 235 26 and and CC cord-334550-xb0alubj 235 27 decreasing decrease VBG cord-334550-xb0alubj 235 28 the the DT cord-334550-xb0alubj 235 29 severity severity NN cord-334550-xb0alubj 235 30 of of IN cord-334550-xb0alubj 235 31 encephalomyocarditis encephalomyocarditis NNP cord-334550-xb0alubj 235 32 virus virus NN cord-334550-xb0alubj 235 33 infection infection NN cord-334550-xb0alubj 235 34 in in IN cord-334550-xb0alubj 235 35 mice mouse NNS cord-334550-xb0alubj 235 36 ( ( -LRB- cord-334550-xb0alubj 235 37 Floc'h Floc'h NNP cord-334550-xb0alubj 235 38 and and CC cord-334550-xb0alubj 235 39 Werner Werner NNP cord-334550-xb0alubj 235 40 , , , cord-334550-xb0alubj 235 41 1976 1976 CD cord-334550-xb0alubj 235 42 ) ) -RRB- cord-334550-xb0alubj 235 43 . . . cord-334550-xb0alubj 236 1 Researchers researcher NNS cord-334550-xb0alubj 236 2 from from IN cord-334550-xb0alubj 236 3 New New NNP cord-334550-xb0alubj 236 4 York York NNP cord-334550-xb0alubj 236 5 Institute Institute NNP cord-334550-xb0alubj 236 6 of of IN cord-334550-xb0alubj 236 7 Technology Technology NNP cord-334550-xb0alubj 236 8 correlated correlate VBD cord-334550-xb0alubj 236 9 global global JJ cord-334550-xb0alubj 236 10 COVID-19 covid-19 CD cord-334550-xb0alubj 236 11 transmission transmission NN cord-334550-xb0alubj 236 12 with with IN cord-334550-xb0alubj 236 13 BCG BCG NNP cord-334550-xb0alubj 236 14 vaccine vaccine NN cord-334550-xb0alubj 236 15 coverage coverage NN cord-334550-xb0alubj 236 16 data datum NNS cord-334550-xb0alubj 236 17 and and CC cord-334550-xb0alubj 236 18 observed observe VBD cord-334550-xb0alubj 236 19 that that IN cord-334550-xb0alubj 236 20 countries country NNS cord-334550-xb0alubj 236 21 with with IN cord-334550-xb0alubj 236 22 a a DT cord-334550-xb0alubj 236 23 policy policy NN cord-334550-xb0alubj 236 24 for for IN cord-334550-xb0alubj 236 25 universal universal JJ cord-334550-xb0alubj 236 26 BCG BCG NNP cord-334550-xb0alubj 236 27 vaccination vaccination NN cord-334550-xb0alubj 236 28 have have VBP cord-334550-xb0alubj 236 29 lower low JJR cord-334550-xb0alubj 236 30 number number NN cord-334550-xb0alubj 236 31 of of IN cord-334550-xb0alubj 236 32 COVID-19 covid-19 JJ cord-334550-xb0alubj 236 33 cases case NNS cord-334550-xb0alubj 236 34 than than IN cord-334550-xb0alubj 236 35 those those DT cord-334550-xb0alubj 236 36 without without IN cord-334550-xb0alubj 236 37 such such JJ cord-334550-xb0alubj 236 38 policy policy NN cord-334550-xb0alubj 236 39 , , , cord-334550-xb0alubj 236 40 such such JJ cord-334550-xb0alubj 236 41 as as IN cord-334550-xb0alubj 236 42 the the DT cord-334550-xb0alubj 236 43 United United NNP cord-334550-xb0alubj 236 44 States States NNP cord-334550-xb0alubj 236 45 and and CC cord-334550-xb0alubj 236 46 Italy Italy NNP cord-334550-xb0alubj 237 1 ( ( -LRB- cord-334550-xb0alubj 237 2 Miller Miller NNP cord-334550-xb0alubj 237 3 et et NNP cord-334550-xb0alubj 237 4 al al NNP cord-334550-xb0alubj 237 5 . . NNP cord-334550-xb0alubj 237 6 , , , cord-334550-xb0alubj 237 7 2020 2020 CD cord-334550-xb0alubj 237 8 ) ) -RRB- cord-334550-xb0alubj 237 9 . . . cord-334550-xb0alubj 238 1 Japan Japan NNP cord-334550-xb0alubj 238 2 , , , cord-334550-xb0alubj 238 3 where where WRB cord-334550-xb0alubj 238 4 universal universal JJ cord-334550-xb0alubj 238 5 BCG BCG NNP cord-334550-xb0alubj 238 6 vaccination vaccination NN cord-334550-xb0alubj 238 7 policy policy NN cord-334550-xb0alubj 238 8 is be VBZ cord-334550-xb0alubj 238 9 in in IN cord-334550-xb0alubj 238 10 place place NN cord-334550-xb0alubj 238 11 since since IN cord-334550-xb0alubj 238 12 1947 1947 CD cord-334550-xb0alubj 238 13 , , , cord-334550-xb0alubj 238 14 has have VBZ cord-334550-xb0alubj 238 15 maintained maintain VBN cord-334550-xb0alubj 238 16 a a DT cord-334550-xb0alubj 238 17 low low JJ cord-334550-xb0alubj 238 18 fatality fatality NN cord-334550-xb0alubj 238 19 rate rate NN cord-334550-xb0alubj 238 20 , , , cord-334550-xb0alubj 238 21 despite despite IN cord-334550-xb0alubj 238 22 an an DT cord-334550-xb0alubj 238 23 early early JJ cord-334550-xb0alubj 238 24 spike spike NN cord-334550-xb0alubj 238 25 in in IN cord-334550-xb0alubj 238 26 COVID-19 covid-19 JJ cord-334550-xb0alubj 238 27 cases case NNS cord-334550-xb0alubj 238 28 . . . cord-334550-xb0alubj 239 1 Iran Iran NNP cord-334550-xb0alubj 239 2 , , , cord-334550-xb0alubj 239 3 one one CD cord-334550-xb0alubj 239 4 of of IN cord-334550-xb0alubj 239 5 the the DT cord-334550-xb0alubj 239 6 countries country NNS cord-334550-xb0alubj 239 7 badly badly RB cord-334550-xb0alubj 239 8 hit hit VBN cord-334550-xb0alubj 239 9 by by IN cord-334550-xb0alubj 239 10 this this DT cord-334550-xb0alubj 239 11 pandemic pandemic NN cord-334550-xb0alubj 239 12 , , , cord-334550-xb0alubj 239 13 started start VBD cord-334550-xb0alubj 239 14 universal universal JJ cord-334550-xb0alubj 239 15 BCG BCG NNP cord-334550-xb0alubj 239 16 vaccination vaccination NN cord-334550-xb0alubj 239 17 only only RB cord-334550-xb0alubj 239 18 in in IN cord-334550-xb0alubj 239 19 1984 1984 CD cord-334550-xb0alubj 239 20 , , , cord-334550-xb0alubj 239 21 potentially potentially RB cord-334550-xb0alubj 239 22 leaving leave VBG cord-334550-xb0alubj 239 23 anyone anyone NN cord-334550-xb0alubj 239 24 above above IN cord-334550-xb0alubj 239 25 36 36 CD cord-334550-xb0alubj 239 26 years year NNS cord-334550-xb0alubj 239 27 of of IN cord-334550-xb0alubj 239 28 age age NN cord-334550-xb0alubj 239 29 unprotected unprotected JJ cord-334550-xb0alubj 239 30 . . . cord-334550-xb0alubj 240 1 However however RB cord-334550-xb0alubj 240 2 , , , cord-334550-xb0alubj 240 3 according accord VBG cord-334550-xb0alubj 240 4 to to IN cord-334550-xb0alubj 240 5 WHO WHO NNP cord-334550-xb0alubj 240 6 , , , cord-334550-xb0alubj 240 7 such such JJ cord-334550-xb0alubj 240 8 comparisons comparison NNS cord-334550-xb0alubj 240 9 are be VBP cord-334550-xb0alubj 240 10 prone prone JJ cord-334550-xb0alubj 240 11 to to IN cord-334550-xb0alubj 240 12 significant significant JJ cord-334550-xb0alubj 240 13 bias bias NN cord-334550-xb0alubj 240 14 from from IN cord-334550-xb0alubj 240 15 many many JJ cord-334550-xb0alubj 240 16 confounders confounder NNS cord-334550-xb0alubj 240 17 , , , cord-334550-xb0alubj 240 18 including include VBG cord-334550-xb0alubj 240 19 variations variation NNS cord-334550-xb0alubj 240 20 in in IN cord-334550-xb0alubj 240 21 demographics demographic NNS cord-334550-xb0alubj 240 22 and and CC cord-334550-xb0alubj 240 23 disease disease NN cord-334550-xb0alubj 240 24 burden burden NN cord-334550-xb0alubj 240 25 , , , cord-334550-xb0alubj 240 26 COVID-19 covid-19 JJ cord-334550-xb0alubj 240 27 testing testing NN cord-334550-xb0alubj 240 28 rates rate NNS cord-334550-xb0alubj 240 29 and and CC cord-334550-xb0alubj 240 30 the the DT cord-334550-xb0alubj 240 31 stage stage NN cord-334550-xb0alubj 240 32 of of IN cord-334550-xb0alubj 240 33 the the DT cord-334550-xb0alubj 240 34 pandemic pandemic NN cord-334550-xb0alubj 240 35 in in IN cord-334550-xb0alubj 240 36 each each DT cord-334550-xb0alubj 240 37 country country NN cord-334550-xb0alubj 240 38 . . . cord-334550-xb0alubj 241 1 9 9 CD cord-334550-xb0alubj 242 1 Two two CD cord-334550-xb0alubj 242 2 randomized randomized JJ cord-334550-xb0alubj 242 3 controlled control VBN cord-334550-xb0alubj 242 4 trials trial NNS cord-334550-xb0alubj 242 5 , , , cord-334550-xb0alubj 242 6 BCG BCG NNP cord-334550-xb0alubj 242 7 - - HYPH cord-334550-xb0alubj 242 8 CORONA CORONA NNP cord-334550-xb0alubj 242 9 ( ( -LRB- cord-334550-xb0alubj 242 10 NCT04328441 NCT04328441 NNP cord-334550-xb0alubj 242 11 ) ) -RRB- cord-334550-xb0alubj 242 12 and and CC cord-334550-xb0alubj 242 13 BRACE BRACE NNP cord-334550-xb0alubj 242 14 ( ( -LRB- cord-334550-xb0alubj 242 15 NCT04327206 NCT04327206 NNP cord-334550-xb0alubj 242 16 ) ) -RRB- cord-334550-xb0alubj 242 17 trials trial NNS cord-334550-xb0alubj 242 18 are be VBP cord-334550-xb0alubj 242 19 underway underway JJ cord-334550-xb0alubj 242 20 , , , cord-334550-xb0alubj 242 21 evaluating evaluate VBG cord-334550-xb0alubj 242 22 the the DT cord-334550-xb0alubj 242 23 efficacy efficacy NN cord-334550-xb0alubj 242 24 of of IN cord-334550-xb0alubj 242 25 BCG BCG NNP cord-334550-xb0alubj 242 26 vaccine vaccine NN cord-334550-xb0alubj 242 27 in in IN cord-334550-xb0alubj 242 28 reducing reduce VBG cord-334550-xb0alubj 242 29 the the DT cord-334550-xb0alubj 242 30 viral viral JJ cord-334550-xb0alubj 242 31 load load NN cord-334550-xb0alubj 243 1 and/or and/or CC cord-334550-xb0alubj 243 2 sequelae sequela NNS cord-334550-xb0alubj 243 3 associated associate VBN cord-334550-xb0alubj 243 4 with with IN cord-334550-xb0alubj 243 5 COVID-19 COVID-19 NNP cord-334550-xb0alubj 243 6 . . . cord-334550-xb0alubj 244 1 One one CD cord-334550-xb0alubj 244 2 limitation limitation NN cord-334550-xb0alubj 244 3 of of IN cord-334550-xb0alubj 244 4 BCG BCG NNP cord-334550-xb0alubj 244 5 vaccination vaccination NN cord-334550-xb0alubj 244 6 is be VBZ cord-334550-xb0alubj 244 7 seroconversion seroconversion NN cord-334550-xb0alubj 244 8 , , , cord-334550-xb0alubj 244 9 which which WDT cord-334550-xb0alubj 244 10 is be VBZ cord-334550-xb0alubj 244 11 the the DT cord-334550-xb0alubj 244 12 basis basis NN cord-334550-xb0alubj 244 13 for for IN cord-334550-xb0alubj 244 14 diagnosis diagnosis NN cord-334550-xb0alubj 244 15 of of IN cord-334550-xb0alubj 244 16 TB TB NNP cord-334550-xb0alubj 244 17 in in IN cord-334550-xb0alubj 244 18 several several JJ cord-334550-xb0alubj 244 19 countries country NNS cord-334550-xb0alubj 244 20 . . . cord-334550-xb0alubj 245 1 Therefore therefore RB cord-334550-xb0alubj 245 2 , , , cord-334550-xb0alubj 245 3 MMR MMR NNP cord-334550-xb0alubj 245 4 , , , cord-334550-xb0alubj 245 5 another another DT cord-334550-xb0alubj 245 6 live live JJ cord-334550-xb0alubj 245 7 attenuated attenuated JJ cord-334550-xb0alubj 245 8 vaccine vaccine NN cord-334550-xb0alubj 245 9 , , , cord-334550-xb0alubj 245 10 might may MD cord-334550-xb0alubj 245 11 be be VB cord-334550-xb0alubj 245 12 a a DT cord-334550-xb0alubj 245 13 potential potential JJ cord-334550-xb0alubj 245 14 option option NN cord-334550-xb0alubj 245 15 for for IN cord-334550-xb0alubj 245 16 inducing induce VBG cord-334550-xb0alubj 245 17 beneficial beneficial JJ cord-334550-xb0alubj 245 18 non non JJ cord-334550-xb0alubj 245 19 - - JJ cord-334550-xb0alubj 245 20 specific specific JJ cord-334550-xb0alubj 245 21 effects effect NNS cord-334550-xb0alubj 245 22 in in IN cord-334550-xb0alubj 245 23 human human JJ cord-334550-xb0alubj 245 24 populations population NNS cord-334550-xb0alubj 245 25 and and CC cord-334550-xb0alubj 245 26 thus thus RB cord-334550-xb0alubj 245 27 provide provide VB cord-334550-xb0alubj 245 28 protection protection NN cord-334550-xb0alubj 245 29 against against IN cord-334550-xb0alubj 245 30 the the DT cord-334550-xb0alubj 245 31 catastrophic catastrophic JJ cord-334550-xb0alubj 245 32 sequelae sequela NNS cord-334550-xb0alubj 245 33 of of IN cord-334550-xb0alubj 245 34 COVID-19 COVID-19 NNP cord-334550-xb0alubj 245 35 . . . cord-334550-xb0alubj 246 1 A a DT cord-334550-xb0alubj 246 2 strong strong JJ cord-334550-xb0alubj 246 3 correlation correlation NN cord-334550-xb0alubj 246 4 has have VBZ cord-334550-xb0alubj 246 5 been be VBN cord-334550-xb0alubj 246 6 observed observe VBN cord-334550-xb0alubj 246 7 between between IN cord-334550-xb0alubj 246 8 individuals individual NNS cord-334550-xb0alubj 246 9 in in IN cord-334550-xb0alubj 246 10 geographical geographical JJ cord-334550-xb0alubj 246 11 locations location NNS cord-334550-xb0alubj 246 12 who who WP cord-334550-xb0alubj 246 13 received receive VBD cord-334550-xb0alubj 246 14 MMR MMR NNP cord-334550-xb0alubj 246 15 vaccine vaccine NN cord-334550-xb0alubj 246 16 and and CC cord-334550-xb0alubj 246 17 reduced reduce VBD cord-334550-xb0alubj 246 18 COVID-19 COVID-19 NNP cord-334550-xb0alubj 246 19 death death NN cord-334550-xb0alubj 246 20 rates rate NNS cord-334550-xb0alubj 246 21 ( ( -LRB- cord-334550-xb0alubj 246 22 Gold gold NN cord-334550-xb0alubj 246 23 , , , cord-334550-xb0alubj 246 24 2020 2020 CD cord-334550-xb0alubj 246 25 ) ) -RRB- cord-334550-xb0alubj 246 26 . . . cord-334550-xb0alubj 247 1 Interestingly interestingly RB cord-334550-xb0alubj 247 2 , , , cord-334550-xb0alubj 247 3 despite despite IN cord-334550-xb0alubj 247 4 children child NNS cord-334550-xb0alubj 247 5 being be VBG cord-334550-xb0alubj 247 6 highly highly RB cord-334550-xb0alubj 247 7 susceptibility susceptibility NN cord-334550-xb0alubj 247 8 to to IN cord-334550-xb0alubj 247 9 flu flu NN cord-334550-xb0alubj 247 10 , , , cord-334550-xb0alubj 247 11 very very RB cord-334550-xb0alubj 247 12 few few JJ cord-334550-xb0alubj 247 13 children child NNS cord-334550-xb0alubj 247 14 have have VBP cord-334550-xb0alubj 247 15 been be VBN cord-334550-xb0alubj 247 16 affected affect VBN cord-334550-xb0alubj 247 17 during during IN cord-334550-xb0alubj 247 18 the the DT cord-334550-xb0alubj 247 19 ongoing ongoing JJ cord-334550-xb0alubj 247 20 COVID-19 covid-19 JJ cord-334550-xb0alubj 247 21 pandemic pandemic NN cord-334550-xb0alubj 247 22 . . . cord-334550-xb0alubj 248 1 Also also RB cord-334550-xb0alubj 248 2 , , , cord-334550-xb0alubj 248 3 there there EX cord-334550-xb0alubj 248 4 has have VBZ cord-334550-xb0alubj 248 5 been be VBN cord-334550-xb0alubj 248 6 a a DT cord-334550-xb0alubj 248 7 striking striking JJ cord-334550-xb0alubj 248 8 difference difference NN cord-334550-xb0alubj 248 9 in in IN cord-334550-xb0alubj 248 10 the the DT cord-334550-xb0alubj 248 11 COVID-19 COVID-19 NNP cord-334550-xb0alubj 248 12 mortality mortality NN cord-334550-xb0alubj 248 13 rates rate NNS cord-334550-xb0alubj 248 14 between between IN cord-334550-xb0alubj 248 15 children child NNS cord-334550-xb0alubj 248 16 and and CC cord-334550-xb0alubj 248 17 adults adult NNS cord-334550-xb0alubj 248 18 . . . cord-334550-xb0alubj 249 1 One one CD cord-334550-xb0alubj 249 2 explanation explanation NN cord-334550-xb0alubj 249 3 is be VBZ cord-334550-xb0alubj 249 4 that that IN cord-334550-xb0alubj 249 5 children child NNS cord-334550-xb0alubj 249 6 are be VBP cord-334550-xb0alubj 249 7 protected protect VBN cord-334550-xb0alubj 249 8 owing owe VBG cord-334550-xb0alubj 249 9 to to IN cord-334550-xb0alubj 249 10 their -PRON- PRP$ cord-334550-xb0alubj 249 11 recent recent JJ cord-334550-xb0alubj 249 12 and and CC cord-334550-xb0alubj 249 13 more more RBR cord-334550-xb0alubj 249 14 frequent frequent JJ cord-334550-xb0alubj 249 15 exposures exposure NNS cord-334550-xb0alubj 249 16 to to TO cord-334550-xb0alubj 249 17 live live VB cord-334550-xb0alubj 249 18 attenuated attenuated JJ cord-334550-xb0alubj 249 19 vaccines vaccine NNS cord-334550-xb0alubj 249 20 ( ( -LRB- cord-334550-xb0alubj 249 21 BCG BCG NNP cord-334550-xb0alubj 249 22 , , , cord-334550-xb0alubj 249 23 MMR MMR NNP cord-334550-xb0alubj 249 24 , , , cord-334550-xb0alubj 249 25 chickenpox chickenpox NN cord-334550-xb0alubj 249 26 and and CC cord-334550-xb0alubj 249 27 rotavirus rotavirus NN cord-334550-xb0alubj 249 28 ) ) -RRB- cord-334550-xb0alubj 249 29 which which WDT cord-334550-xb0alubj 249 30 can can MD cord-334550-xb0alubj 249 31 induce induce VB cord-334550-xb0alubj 249 32 the the DT cord-334550-xb0alubj 249 33 trained train VBN cord-334550-xb0alubj 249 34 myeloid myeloid NN cord-334550-xb0alubj 249 35 - - HYPH cord-334550-xb0alubj 249 36 derived derive VBN cord-334550-xb0alubj 249 37 suppressor suppressor NN cord-334550-xb0alubj 249 38 cells cell NNS cord-334550-xb0alubj 249 39 and and CC cord-334550-xb0alubj 249 40 thus thus RB cord-334550-xb0alubj 249 41 limit limit VB cord-334550-xb0alubj 249 42 disease disease NN cord-334550-xb0alubj 249 43 severity severity NN cord-334550-xb0alubj 249 44 ( ( -LRB- cord-334550-xb0alubj 249 45 Fidel Fidel NNP cord-334550-xb0alubj 249 46 and and CC cord-334550-xb0alubj 249 47 Noverr Noverr NNP cord-334550-xb0alubj 249 48 , , , cord-334550-xb0alubj 249 49 2020 2020 CD cord-334550-xb0alubj 249 50 ) ) -RRB- cord-334550-xb0alubj 249 51 . . . cord-334550-xb0alubj 250 1 Though though IN cord-334550-xb0alubj 250 2 conclusive conclusive JJ cord-334550-xb0alubj 250 3 evidence evidence NN cord-334550-xb0alubj 250 4 on on IN cord-334550-xb0alubj 250 5 this this DT cord-334550-xb0alubj 250 6 ground ground NN cord-334550-xb0alubj 250 7 is be VBZ cord-334550-xb0alubj 250 8 lacking lack VBG cord-334550-xb0alubj 250 9 at at IN cord-334550-xb0alubj 250 10 the the DT cord-334550-xb0alubj 250 11 moment moment NN cord-334550-xb0alubj 250 12 , , , cord-334550-xb0alubj 250 13 considering consider VBG cord-334550-xb0alubj 250 14 the the DT cord-334550-xb0alubj 250 15 positive positive JJ cord-334550-xb0alubj 250 16 correlation correlation NN cord-334550-xb0alubj 250 17 between between IN cord-334550-xb0alubj 250 18 the the DT cord-334550-xb0alubj 250 19 use use NN cord-334550-xb0alubj 250 20 of of IN cord-334550-xb0alubj 250 21 live live JJ cord-334550-xb0alubj 250 22 attenuated attenuated JJ cord-334550-xb0alubj 250 23 vaccines vaccine NNS cord-334550-xb0alubj 250 24 and and CC cord-334550-xb0alubj 250 25 lower low JJR cord-334550-xb0alubj 250 26 COVID-19 covid-19 JJ cord-334550-xb0alubj 250 27 severity severity NN cord-334550-xb0alubj 250 28 and and CC cord-334550-xb0alubj 250 29 death death NN cord-334550-xb0alubj 250 30 rates rate NNS cord-334550-xb0alubj 250 31 , , , cord-334550-xb0alubj 250 32 hopes hope NNS cord-334550-xb0alubj 250 33 remain remain VBP cord-334550-xb0alubj 250 34 high high JJ cord-334550-xb0alubj 250 35 for for IN cord-334550-xb0alubj 250 36 a a DT cord-334550-xb0alubj 250 37 possible possible JJ cord-334550-xb0alubj 250 38 protective protective JJ cord-334550-xb0alubj 250 39 action action NN cord-334550-xb0alubj 250 40 of of IN cord-334550-xb0alubj 250 41 these these DT cord-334550-xb0alubj 250 42 vaccines vaccine NNS cord-334550-xb0alubj 250 43 against against IN cord-334550-xb0alubj 250 44 SARS SARS NNP cord-334550-xb0alubj 250 45 - - HYPH cord-334550-xb0alubj 250 46 CoV-2 CoV-2 NNP cord-334550-xb0alubj 250 47 . . . cord-334550-xb0alubj 251 1 India India NNP cord-334550-xb0alubj 251 2 is be VBZ cord-334550-xb0alubj 251 3 a a DT cord-334550-xb0alubj 251 4 vast vast JJ cord-334550-xb0alubj 251 5 country country NN cord-334550-xb0alubj 251 6 with with IN cord-334550-xb0alubj 251 7 varied varied JJ cord-334550-xb0alubj 251 8 weather weather NN cord-334550-xb0alubj 251 9 conditions condition NNS cord-334550-xb0alubj 251 10 . . . cord-334550-xb0alubj 252 1 The the DT cord-334550-xb0alubj 252 2 western western JJ cord-334550-xb0alubj 252 3 part part NN cord-334550-xb0alubj 252 4 of of IN cord-334550-xb0alubj 252 5 the the DT cord-334550-xb0alubj 252 6 country country NN cord-334550-xb0alubj 252 7 is be VBZ cord-334550-xb0alubj 252 8 known know VBN cord-334550-xb0alubj 252 9 for for IN cord-334550-xb0alubj 252 10 hot hot JJ cord-334550-xb0alubj 252 11 dry dry JJ cord-334550-xb0alubj 252 12 summers summer NNS cord-334550-xb0alubj 252 13 with with IN cord-334550-xb0alubj 252 14 temperatures temperature NNS cord-334550-xb0alubj 252 15 exceeding exceed VBG cord-334550-xb0alubj 252 16 50 50 CD cord-334550-xb0alubj 252 17 • • NNS cord-334550-xb0alubj 252 18 C c NN cord-334550-xb0alubj 252 19 , , , cord-334550-xb0alubj 252 20 while while IN cord-334550-xb0alubj 252 21 the the DT cord-334550-xb0alubj 252 22 Himalayan Himalayan NNP cord-334550-xb0alubj 252 23 belt belt NN cord-334550-xb0alubj 252 24 in in IN cord-334550-xb0alubj 252 25 the the DT cord-334550-xb0alubj 252 26 northern northern JJ cord-334550-xb0alubj 252 27 part part NN cord-334550-xb0alubj 252 28 records record VBZ cord-334550-xb0alubj 252 29 temperatures temperature NNS cord-334550-xb0alubj 252 30 as as RB cord-334550-xb0alubj 252 31 low low JJ cord-334550-xb0alubj 252 32 as as IN cord-334550-xb0alubj 252 33 −30 −30 NNP cord-334550-xb0alubj 253 1 • • NNP cord-334550-xb0alubj 254 1 C. C. NNP cord-334550-xb0alubj 254 2 Previous previous JJ cord-334550-xb0alubj 254 3 studies study NNS cord-334550-xb0alubj 254 4 have have VBP cord-334550-xb0alubj 254 5 shown show VBN cord-334550-xb0alubj 254 6 the the DT cord-334550-xb0alubj 254 7 impact impact NN cord-334550-xb0alubj 254 8 of of IN cord-334550-xb0alubj 254 9 weather weather NN cord-334550-xb0alubj 254 10 variables variable NNS cord-334550-xb0alubj 254 11 on on IN cord-334550-xb0alubj 254 12 the the DT cord-334550-xb0alubj 254 13 transmission transmission NN cord-334550-xb0alubj 254 14 dynamics dynamic NNS cord-334550-xb0alubj 254 15 of of IN cord-334550-xb0alubj 254 16 diseases disease NNS cord-334550-xb0alubj 254 17 like like IN cord-334550-xb0alubj 254 18 influenza influenza NN cord-334550-xb0alubj 254 19 and and CC cord-334550-xb0alubj 254 20 SARS SARS NNP cord-334550-xb0alubj 254 21 . . . cord-334550-xb0alubj 255 1 Transmission transmission NN cord-334550-xb0alubj 255 2 of of IN cord-334550-xb0alubj 255 3 influenza influenza NN cord-334550-xb0alubj 255 4 is be VBZ cord-334550-xb0alubj 255 5 facilitated facilitate VBN cord-334550-xb0alubj 255 6 in in IN cord-334550-xb0alubj 255 7 the the DT cord-334550-xb0alubj 255 8 presence presence NN cord-334550-xb0alubj 255 9 of of IN cord-334550-xb0alubj 255 10 cold cold JJ cord-334550-xb0alubj 255 11 and/or and/or CC cord-334550-xb0alubj 255 12 dry dry JJ cord-334550-xb0alubj 255 13 air air NN cord-334550-xb0alubj 255 14 . . . cord-334550-xb0alubj 256 1 A a DT cord-334550-xb0alubj 256 2 sharp sharp JJ cord-334550-xb0alubj 256 3 rise rise NN cord-334550-xb0alubj 256 4 in in IN cord-334550-xb0alubj 256 5 influenza influenza NN cord-334550-xb0alubj 256 6 virus virus NN cord-334550-xb0alubj 256 7 activity activity NN cord-334550-xb0alubj 256 8 in in IN cord-334550-xb0alubj 256 9 northern northern JJ cord-334550-xb0alubj 256 10 Europe Europe NNP cord-334550-xb0alubj 256 11 during during IN cord-334550-xb0alubj 256 12 2010 2010 CD cord-334550-xb0alubj 256 13 - - SYM cord-334550-xb0alubj 256 14 2018 2018 CD cord-334550-xb0alubj 256 15 was be VBD cord-334550-xb0alubj 256 16 correlated correlate VBN cord-334550-xb0alubj 256 17 with with IN cord-334550-xb0alubj 256 18 low low JJ cord-334550-xb0alubj 256 19 temperature temperature NN cord-334550-xb0alubj 256 20 and and CC cord-334550-xb0alubj 256 21 low low JJ cord-334550-xb0alubj 256 22 ultraviolet ultraviolet NN cord-334550-xb0alubj 256 23 ( ( -LRB- cord-334550-xb0alubj 256 24 UV uv NN cord-334550-xb0alubj 256 25 ) ) -RRB- cord-334550-xb0alubj 256 26 radiation radiation NN cord-334550-xb0alubj 256 27 indices index NNS cord-334550-xb0alubj 256 28 . . . cord-334550-xb0alubj 257 1 Based base VBN cord-334550-xb0alubj 257 2 on on IN cord-334550-xb0alubj 257 3 these these DT cord-334550-xb0alubj 257 4 facts fact NNS cord-334550-xb0alubj 257 5 , , , cord-334550-xb0alubj 257 6 it -PRON- PRP cord-334550-xb0alubj 257 7 was be VBD cord-334550-xb0alubj 257 8 assumed assume VBN cord-334550-xb0alubj 257 9 that that IN cord-334550-xb0alubj 257 10 COVID-19 covid-19 JJ cord-334550-xb0alubj 257 11 transmission transmission NN cord-334550-xb0alubj 257 12 might may MD cord-334550-xb0alubj 257 13 decrease decrease VB cord-334550-xb0alubj 257 14 or or CC cord-334550-xb0alubj 257 15 even even RB cord-334550-xb0alubj 257 16 disappear disappear VB cord-334550-xb0alubj 257 17 with with IN cord-334550-xb0alubj 257 18 the the DT cord-334550-xb0alubj 257 19 rise rise NN cord-334550-xb0alubj 257 20 in in IN cord-334550-xb0alubj 257 21 ambient ambient JJ cord-334550-xb0alubj 257 22 temperature temperature NN cord-334550-xb0alubj 257 23 and and CC cord-334550-xb0alubj 257 24 UV uv NN cord-334550-xb0alubj 257 25 radiation radiation NN cord-334550-xb0alubj 257 26 during during IN cord-334550-xb0alubj 257 27 the the DT cord-334550-xb0alubj 257 28 summer summer NN cord-334550-xb0alubj 257 29 months month NNS cord-334550-xb0alubj 257 30 . . . cord-334550-xb0alubj 258 1 However however RB cord-334550-xb0alubj 258 2 , , , cord-334550-xb0alubj 258 3 a a DT cord-334550-xb0alubj 258 4 study study NN cord-334550-xb0alubj 258 5 by by IN cord-334550-xb0alubj 258 6 Yao Yao NNP cord-334550-xb0alubj 258 7 et et FW cord-334550-xb0alubj 258 8 al al NNP cord-334550-xb0alubj 258 9 . . . cord-334550-xb0alubj 259 1 ( ( -LRB- cord-334550-xb0alubj 259 2 2020 2020 CD cord-334550-xb0alubj 259 3 ) ) -RRB- cord-334550-xb0alubj 259 4 incorporating incorporate VBG cord-334550-xb0alubj 259 5 meteorological meteorological JJ cord-334550-xb0alubj 259 6 data datum NNS cord-334550-xb0alubj 259 7 and and CC cord-334550-xb0alubj 259 8 basic basic JJ cord-334550-xb0alubj 259 9 reproduction reproduction NN cord-334550-xb0alubj 259 10 number number NN cord-334550-xb0alubj 259 11 ( ( -LRB- cord-334550-xb0alubj 259 12 R r NN cord-334550-xb0alubj 259 13 0 0 CD cord-334550-xb0alubj 259 14 ) ) -RRB- cord-334550-xb0alubj 259 15 of of IN cord-334550-xb0alubj 259 16 the the DT cord-334550-xb0alubj 259 17 virus virus NN cord-334550-xb0alubj 259 18 from from IN cord-334550-xb0alubj 259 19 224 224 CD cord-334550-xb0alubj 259 20 Chinese chinese JJ cord-334550-xb0alubj 259 21 cities city NNS cord-334550-xb0alubj 259 22 revealed reveal VBD cord-334550-xb0alubj 259 23 that that IN cord-334550-xb0alubj 259 24 high high JJ cord-334550-xb0alubj 259 25 temperature temperature NN cord-334550-xb0alubj 259 26 , , , cord-334550-xb0alubj 259 27 humidity humidity NN cord-334550-xb0alubj 259 28 and and CC cord-334550-xb0alubj 259 29 UV uv NN cord-334550-xb0alubj 259 30 radiation radiation NN cord-334550-xb0alubj 259 31 has have VBZ cord-334550-xb0alubj 259 32 no no DT cord-334550-xb0alubj 259 33 significant significant JJ cord-334550-xb0alubj 259 34 impact impact NN cord-334550-xb0alubj 259 35 on on IN cord-334550-xb0alubj 259 36 cumulative cumulative JJ cord-334550-xb0alubj 259 37 incidence incidence NN cord-334550-xb0alubj 259 38 rate rate NN cord-334550-xb0alubj 259 39 and and CC cord-334550-xb0alubj 259 40 transmission transmission NN cord-334550-xb0alubj 259 41 of of IN cord-334550-xb0alubj 259 42 SARS SARS NNP cord-334550-xb0alubj 259 43 - - HYPH cord-334550-xb0alubj 259 44 CoV-2 CoV-2 NNP cord-334550-xb0alubj 259 45 . . . cord-334550-xb0alubj 260 1 Infact infact RB cord-334550-xb0alubj 260 2 , , , cord-334550-xb0alubj 260 3 countries country NNS cord-334550-xb0alubj 260 4 like like IN cord-334550-xb0alubj 260 5 Iran Iran NNP cord-334550-xb0alubj 260 6 and and CC cord-334550-xb0alubj 260 7 Australia Australia NNP cord-334550-xb0alubj 260 8 continued continue VBD cord-334550-xb0alubj 260 9 to to TO cord-334550-xb0alubj 260 10 have have VB cord-334550-xb0alubj 260 11 rapid rapid JJ cord-334550-xb0alubj 260 12 disease disease NN cord-334550-xb0alubj 260 13 transmission transmission NN cord-334550-xb0alubj 260 14 and and CC cord-334550-xb0alubj 260 15 exponential exponential JJ cord-334550-xb0alubj 260 16 rise rise NN cord-334550-xb0alubj 260 17 in in IN cord-334550-xb0alubj 260 18 the the DT cord-334550-xb0alubj 260 19 number number NN cord-334550-xb0alubj 260 20 of of IN cord-334550-xb0alubj 260 21 cases case NNS cord-334550-xb0alubj 260 22 despite despite IN cord-334550-xb0alubj 260 23 high high JJ cord-334550-xb0alubj 260 24 temperature temperature NN cord-334550-xb0alubj 260 25 and and CC cord-334550-xb0alubj 260 26 humidity humidity NN cord-334550-xb0alubj 260 27 , , , cord-334550-xb0alubj 260 28 indicating indicate VBG cord-334550-xb0alubj 260 29 that that IN cord-334550-xb0alubj 260 30 the the DT cord-334550-xb0alubj 260 31 inverse inverse JJ cord-334550-xb0alubj 260 32 relationship relationship NN cord-334550-xb0alubj 260 33 between between IN cord-334550-xb0alubj 260 34 ambient ambient JJ cord-334550-xb0alubj 260 35 temperature temperature NN cord-334550-xb0alubj 260 36 and and CC cord-334550-xb0alubj 260 37 COVID-19 covid-19 JJ cord-334550-xb0alubj 260 38 transmission transmission NN cord-334550-xb0alubj 260 39 lacks lack VBZ cord-334550-xb0alubj 260 40 rationality rationality NN cord-334550-xb0alubj 260 41 . . . cord-334550-xb0alubj 261 1 Studies study NNS cord-334550-xb0alubj 261 2 have have VBP cord-334550-xb0alubj 261 3 shown show VBN cord-334550-xb0alubj 261 4 that that IN cord-334550-xb0alubj 261 5 an an DT cord-334550-xb0alubj 261 6 interplay interplay NN cord-334550-xb0alubj 261 7 between between IN cord-334550-xb0alubj 261 8 macrodomain macrodomain NN cord-334550-xb0alubj 261 9 ( ( -LRB- cord-334550-xb0alubj 261 10 MAC MAC NNP cord-334550-xb0alubj 261 11 ) ) -RRB- cord-334550-xb0alubj 261 12 and and CC cord-334550-xb0alubj 261 13 papain papain NN cord-334550-xb0alubj 261 14 - - HYPH cord-334550-xb0alubj 261 15 like like JJ cord-334550-xb0alubj 261 16 protease protease NN cord-334550-xb0alubj 261 17 2 2 CD cord-334550-xb0alubj 261 18 ( ( -LRB- cord-334550-xb0alubj 261 19 PLP2 PLP2 NNP cord-334550-xb0alubj 261 20 ) ) -RRB- cord-334550-xb0alubj 261 21 domain domain NN cord-334550-xb0alubj 261 22 of of IN cord-334550-xb0alubj 261 23 coronavirus coronavirus NN cord-334550-xb0alubj 261 24 NSP3 NSP3 NNP cord-334550-xb0alubj 261 25 impacts impact NNS cord-334550-xb0alubj 261 26 viral viral JJ cord-334550-xb0alubj 261 27 replication replication NN cord-334550-xb0alubj 261 28 , , , cord-334550-xb0alubj 261 29 host host NN cord-334550-xb0alubj 261 30 innate innate JJ cord-334550-xb0alubj 261 31 immune immune JJ cord-334550-xb0alubj 261 32 antagonism antagonism NN cord-334550-xb0alubj 261 33 and and CC cord-334550-xb0alubj 261 34 virulence virulence NN cord-334550-xb0alubj 261 35 . . . cord-334550-xb0alubj 262 1 Strains strain NNS cord-334550-xb0alubj 262 2 harboring harbor VBG cord-334550-xb0alubj 262 3 mutations mutation NNS cord-334550-xb0alubj 262 4 in in IN cord-334550-xb0alubj 262 5 these these DT cord-334550-xb0alubj 262 6 two two CD cord-334550-xb0alubj 262 7 domains domain NNS cord-334550-xb0alubj 262 8 are be VBP cord-334550-xb0alubj 262 9 more more RBR cord-334550-xb0alubj 262 10 rapidly rapidly RB cord-334550-xb0alubj 262 11 degraded degrade VBN cord-334550-xb0alubj 262 12 at at IN cord-334550-xb0alubj 262 13 non non JJ cord-334550-xb0alubj 262 14 - - JJ cord-334550-xb0alubj 262 15 permissive permissive JJ cord-334550-xb0alubj 262 16 temperatures temperature NNS cord-334550-xb0alubj 262 17 ( ( -LRB- cord-334550-xb0alubj 262 18 37 37 CD cord-334550-xb0alubj 262 19 • • NN cord-334550-xb0alubj 262 20 C c NN cord-334550-xb0alubj 262 21 and and CC cord-334550-xb0alubj 262 22 40 40 CD cord-334550-xb0alubj 263 1 • • NNP cord-334550-xb0alubj 263 2 C C NNP cord-334550-xb0alubj 263 3 ) ) -RRB- cord-334550-xb0alubj 263 4 than than IN cord-334550-xb0alubj 263 5 the the DT cord-334550-xb0alubj 263 6 wild wild JJ cord-334550-xb0alubj 263 7 - - HYPH cord-334550-xb0alubj 263 8 type type NN cord-334550-xb0alubj 263 9 strains strain NNS cord-334550-xb0alubj 263 10 ( ( -LRB- cord-334550-xb0alubj 263 11 Deng Deng NNP cord-334550-xb0alubj 263 12 et et FW cord-334550-xb0alubj 263 13 al al NNP cord-334550-xb0alubj 263 14 . . NNP cord-334550-xb0alubj 263 15 , , , cord-334550-xb0alubj 263 16 2019 2019 CD cord-334550-xb0alubj 263 17 ) ) -RRB- cord-334550-xb0alubj 263 18 , , . cord-334550-xb0alubj 264 1 indicating indicate VBG cord-334550-xb0alubj 264 2 that that IN cord-334550-xb0alubj 264 3 higher high JJR cord-334550-xb0alubj 264 4 temperatures temperature NNS cord-334550-xb0alubj 264 5 may may MD cord-334550-xb0alubj 264 6 lower lower VB cord-334550-xb0alubj 264 7 the the DT cord-334550-xb0alubj 264 8 virulence virulence NN cord-334550-xb0alubj 264 9 and and CC cord-334550-xb0alubj 264 10 pathogenicity pathogenicity NN cord-334550-xb0alubj 264 11 of of IN cord-334550-xb0alubj 264 12 temperature temperature NN cord-334550-xb0alubj 264 13 - - HYPH cord-334550-xb0alubj 264 14 sensitive sensitive JJ cord-334550-xb0alubj 264 15 SARS SARS NNP cord-334550-xb0alubj 264 16 - - HYPH cord-334550-xb0alubj 264 17 CoV-2 CoV-2 NNP cord-334550-xb0alubj 264 18 mutants mutant NNS cord-334550-xb0alubj 264 19 . . . cord-334550-xb0alubj 265 1 The the DT cord-334550-xb0alubj 265 2 COVID-19 covid-19 JJ cord-334550-xb0alubj 265 3 fatality fatality NN cord-334550-xb0alubj 265 4 rate rate NN cord-334550-xb0alubj 265 5 in in IN cord-334550-xb0alubj 265 6 India India NNP cord-334550-xb0alubj 265 7 is be VBZ cord-334550-xb0alubj 265 8 among among IN cord-334550-xb0alubj 265 9 the the DT cord-334550-xb0alubj 265 10 lowest low JJS cord-334550-xb0alubj 265 11 in in IN cord-334550-xb0alubj 265 12 the the DT cord-334550-xb0alubj 265 13 world world NN cord-334550-xb0alubj 265 14 ( ( -LRB- cord-334550-xb0alubj 265 15 2.8 2.8 CD cord-334550-xb0alubj 265 16 % % NN cord-334550-xb0alubj 265 17 against against IN cord-334550-xb0alubj 265 18 a a DT cord-334550-xb0alubj 265 19 global global JJ cord-334550-xb0alubj 265 20 average average NN cord-334550-xb0alubj 265 21 of of IN cord-334550-xb0alubj 265 22 4.7 4.7 CD cord-334550-xb0alubj 265 23 % % NN cord-334550-xb0alubj 265 24 ) ) -RRB- cord-334550-xb0alubj 265 25 . . . cord-334550-xb0alubj 266 1 Also also RB cord-334550-xb0alubj 266 2 , , , cord-334550-xb0alubj 266 3 the the DT cord-334550-xb0alubj 266 4 disease disease NN cord-334550-xb0alubj 266 5 has have VBZ cord-334550-xb0alubj 266 6 been be VBN cord-334550-xb0alubj 266 7 observed observe VBN cord-334550-xb0alubj 266 8 to to TO cord-334550-xb0alubj 266 9 be be VB cord-334550-xb0alubj 266 10 less less RBR cord-334550-xb0alubj 266 11 severe severe JJ cord-334550-xb0alubj 266 12 among among IN cord-334550-xb0alubj 266 13 Indians Indians NNPS cord-334550-xb0alubj 266 14 with with IN cord-334550-xb0alubj 266 15 a a DT cord-334550-xb0alubj 266 16 significantly significantly RB cord-334550-xb0alubj 266 17 higher high JJR cord-334550-xb0alubj 266 18 recovery recovery NN cord-334550-xb0alubj 266 19 rate rate NN cord-334550-xb0alubj 266 20 ( ( -LRB- cord-334550-xb0alubj 266 21 60.9 60.9 CD cord-334550-xb0alubj 266 22 % % NN cord-334550-xb0alubj 266 23 versus versus IN cord-334550-xb0alubj 266 24 a a DT cord-334550-xb0alubj 266 25 global global JJ cord-334550-xb0alubj 266 26 average average NN cord-334550-xb0alubj 266 27 of of IN cord-334550-xb0alubj 266 28 56.6 56.6 CD cord-334550-xb0alubj 266 29 % % NN cord-334550-xb0alubj 266 30 ) ) -RRB- cord-334550-xb0alubj 266 31 and and CC cord-334550-xb0alubj 266 32 doubling double VBG cord-334550-xb0alubj 266 33 time time NN cord-334550-xb0alubj 266 34 ( ( -LRB- cord-334550-xb0alubj 266 35 20.3 20.3 CD cord-334550-xb0alubj 266 36 days day NNS cord-334550-xb0alubj 266 37 ) ) -RRB- cord-334550-xb0alubj 266 38 as as IN cord-334550-xb0alubj 266 39 compared compare VBN cord-334550-xb0alubj 266 40 to to IN cord-334550-xb0alubj 266 41 the the DT cord-334550-xb0alubj 266 42 populations population NNS cord-334550-xb0alubj 266 43 elsewhere elsewhere RB cord-334550-xb0alubj 266 44 . . . cord-334550-xb0alubj 267 1 3,4,10 3,4,10 CD cord-334550-xb0alubj 267 2 Strict strict JJ cord-334550-xb0alubj 267 3 lockdown lockdown NN cord-334550-xb0alubj 267 4 measures measure NNS cord-334550-xb0alubj 267 5 implemented implement VBN cord-334550-xb0alubj 267 6 nationwide nationwide RB cord-334550-xb0alubj 267 7 for for IN cord-334550-xb0alubj 267 8 more more JJR cord-334550-xb0alubj 267 9 than than IN cord-334550-xb0alubj 267 10 two two CD cord-334550-xb0alubj 267 11 months month NNS cord-334550-xb0alubj 267 12 might may MD cord-334550-xb0alubj 267 13 have have VB cord-334550-xb0alubj 267 14 kept keep VBN cord-334550-xb0alubj 267 15 the the DT cord-334550-xb0alubj 267 16 transmission transmission NN cord-334550-xb0alubj 267 17 and and CC cord-334550-xb0alubj 267 18 deaths death NNS cord-334550-xb0alubj 267 19 in in IN cord-334550-xb0alubj 267 20 check check NN cord-334550-xb0alubj 267 21 . . . cord-334550-xb0alubj 268 1 This this DT cord-334550-xb0alubj 268 2 must must MD cord-334550-xb0alubj 268 3 have have VB cord-334550-xb0alubj 268 4 contributed contribute VBN cord-334550-xb0alubj 268 5 significantly significantly RB cord-334550-xb0alubj 268 6 to to IN cord-334550-xb0alubj 268 7 the the DT cord-334550-xb0alubj 268 8 much much RB cord-334550-xb0alubj 268 9 desired desire VBN cord-334550-xb0alubj 268 10 flattening flattening NN cord-334550-xb0alubj 268 11 of of IN cord-334550-xb0alubj 268 12 the the DT cord-334550-xb0alubj 268 13 epidemic epidemic NN cord-334550-xb0alubj 268 14 curve curve NN cord-334550-xb0alubj 268 15 . . . cord-334550-xb0alubj 269 1 There there EX cord-334550-xb0alubj 269 2 are be VBP cord-334550-xb0alubj 269 3 speculations speculation NNS cord-334550-xb0alubj 269 4 that that IN cord-334550-xb0alubj 269 5 India India NNP cord-334550-xb0alubj 269 6 's 's POS cord-334550-xb0alubj 269 7 predominantly predominantly RB cord-334550-xb0alubj 269 8 young young JJ cord-334550-xb0alubj 269 9 population population NN cord-334550-xb0alubj 269 10 as as IN cord-334550-xb0alubj 269 11 compared compare VBN cord-334550-xb0alubj 269 12 to to IN cord-334550-xb0alubj 269 13 the the DT cord-334550-xb0alubj 269 14 western western JJ cord-334550-xb0alubj 269 15 world world NN cord-334550-xb0alubj 269 16 ( ( -LRB- cord-334550-xb0alubj 269 17 with with IN cord-334550-xb0alubj 269 18 a a DT cord-334550-xb0alubj 269 19 higher high JJR cord-334550-xb0alubj 269 20 proportion proportion NN cord-334550-xb0alubj 269 21 of of IN cord-334550-xb0alubj 269 22 elderly elderly JJ cord-334550-xb0alubj 269 23 people people NNS cord-334550-xb0alubj 269 24 ) ) -RRB- cord-334550-xb0alubj 269 25 , , , cord-334550-xb0alubj 269 26 and and CC cord-334550-xb0alubj 269 27 the the DT cord-334550-xb0alubj 269 28 presence presence NN cord-334550-xb0alubj 269 29 of of IN cord-334550-xb0alubj 269 30 a a DT cord-334550-xb0alubj 269 31 less less RBR cord-334550-xb0alubj 269 32 virulent virulent JJ cord-334550-xb0alubj 269 33 strain strain NN cord-334550-xb0alubj 269 34 of of IN cord-334550-xb0alubj 269 35 the the DT cord-334550-xb0alubj 269 36 virus virus NN cord-334550-xb0alubj 269 37 in in IN cord-334550-xb0alubj 269 38 circulation circulation NN cord-334550-xb0alubj 269 39 are be VBP cord-334550-xb0alubj 269 40 helping help VBG cord-334550-xb0alubj 269 41 keep keep VB cord-334550-xb0alubj 269 42 fatalities fatality NNS cord-334550-xb0alubj 269 43 low low JJ cord-334550-xb0alubj 269 44 in in IN cord-334550-xb0alubj 269 45 India India NNP cord-334550-xb0alubj 269 46 . . . cord-334550-xb0alubj 270 1 However however RB cord-334550-xb0alubj 270 2 , , , cord-334550-xb0alubj 270 3 there there EX cord-334550-xb0alubj 270 4 are be VBP cord-334550-xb0alubj 270 5 no no DT cord-334550-xb0alubj 270 6 evidences evidence NNS cord-334550-xb0alubj 270 7 in in IN cord-334550-xb0alubj 270 8 support support NN cord-334550-xb0alubj 270 9 of of IN cord-334550-xb0alubj 270 10 these these DT cord-334550-xb0alubj 270 11 claims claim NNS cord-334550-xb0alubj 270 12 . . . cord-334550-xb0alubj 271 1 In in IN cord-334550-xb0alubj 271 2 fact fact NN cord-334550-xb0alubj 271 3 , , , cord-334550-xb0alubj 271 4 phylogenetic phylogenetic JJ cord-334550-xb0alubj 271 5 analysis analysis NN cord-334550-xb0alubj 271 6 has have VBZ cord-334550-xb0alubj 271 7 revealed reveal VBN cord-334550-xb0alubj 271 8 that that IN cord-334550-xb0alubj 271 9 four four CD cord-334550-xb0alubj 271 10 clades clade NNS cord-334550-xb0alubj 271 11 of of IN cord-334550-xb0alubj 271 12 the the DT cord-334550-xb0alubj 271 13 virus virus NN cord-334550-xb0alubj 271 14 : : : cord-334550-xb0alubj 271 15 O o UH cord-334550-xb0alubj 271 16 ( ( -LRB- cord-334550-xb0alubj 271 17 ancestral ancestral JJ cord-334550-xb0alubj 271 18 clade clade NN cord-334550-xb0alubj 271 19 from from IN cord-334550-xb0alubj 271 20 China China NNP cord-334550-xb0alubj 271 21 ) ) -RRB- cord-334550-xb0alubj 271 22 , , , cord-334550-xb0alubj 271 23 B B NNP cord-334550-xb0alubj 271 24 ( ( -LRB- cord-334550-xb0alubj 271 25 from from IN cord-334550-xb0alubj 271 26 China China NNP cord-334550-xb0alubj 271 27 ) ) -RRB- cord-334550-xb0alubj 271 28 , , , cord-334550-xb0alubj 271 29 A3 A3 NNP cord-334550-xb0alubj 271 30 ( ( -LRB- cord-334550-xb0alubj 271 31 from from IN cord-334550-xb0alubj 271 32 Iran Iran NNP cord-334550-xb0alubj 271 33 ) ) -RRB- cord-334550-xb0alubj 271 34 and and CC cord-334550-xb0alubj 271 35 A2a a2a NN cord-334550-xb0alubj 271 36 ( ( -LRB- cord-334550-xb0alubj 271 37 from from IN cord-334550-xb0alubj 271 38 Iran Iran NNP cord-334550-xb0alubj 271 39 , , , cord-334550-xb0alubj 271 40 Europe Europe NNP cord-334550-xb0alubj 271 41 , , , cord-334550-xb0alubj 271 42 and and CC cord-334550-xb0alubj 271 43 other other JJ cord-334550-xb0alubj 271 44 countries country NNS cord-334550-xb0alubj 271 45 ) ) -RRB- cord-334550-xb0alubj 271 46 are be VBP cord-334550-xb0alubj 271 47 in in IN cord-334550-xb0alubj 271 48 circulation circulation NN cord-334550-xb0alubj 271 49 in in IN cord-334550-xb0alubj 271 50 India India NNP cord-334550-xb0alubj 271 51 with with IN cord-334550-xb0alubj 271 52 A2a a2a NN cord-334550-xb0alubj 271 53 being be VBG cord-334550-xb0alubj 271 54 the the DT cord-334550-xb0alubj 271 55 dominant dominant JJ cord-334550-xb0alubj 271 56 type type NN cord-334550-xb0alubj 271 57 ( ( -LRB- cord-334550-xb0alubj 271 58 Biswas Biswas NNP cord-334550-xb0alubj 271 59 and and CC cord-334550-xb0alubj 271 60 Majumder Majumder NNP cord-334550-xb0alubj 271 61 , , , cord-334550-xb0alubj 271 62 2020 2020 CD cord-334550-xb0alubj 271 63 ) ) -RRB- cord-334550-xb0alubj 271 64 . . . cord-334550-xb0alubj 272 1 There there EX cord-334550-xb0alubj 272 2 are be VBP cord-334550-xb0alubj 272 3 reports report NNS cord-334550-xb0alubj 272 4 that that IN cord-334550-xb0alubj 272 5 the the DT cord-334550-xb0alubj 272 6 official official JJ cord-334550-xb0alubj 272 7 death death NN cord-334550-xb0alubj 272 8 counts count NNS cord-334550-xb0alubj 272 9 are be VBP cord-334550-xb0alubj 272 10 much much RB cord-334550-xb0alubj 272 11 lower low JJR cord-334550-xb0alubj 272 12 as as IN cord-334550-xb0alubj 272 13 compared compare VBN cord-334550-xb0alubj 272 14 to to IN cord-334550-xb0alubj 272 15 the the DT cord-334550-xb0alubj 272 16 actual actual JJ cord-334550-xb0alubj 272 17 death death NN cord-334550-xb0alubj 272 18 toll toll NN cord-334550-xb0alubj 272 19 . . . cord-334550-xb0alubj 273 1 On on IN cord-334550-xb0alubj 273 2 April April NNP cord-334550-xb0alubj 273 3 18 18 CD cord-334550-xb0alubj 273 4 , , , cord-334550-xb0alubj 273 5 2020 2020 CD cord-334550-xb0alubj 273 6 , , , cord-334550-xb0alubj 273 7 China China NNP cord-334550-xb0alubj 273 8 revised revise VBD cord-334550-xb0alubj 273 9 the the DT cord-334550-xb0alubj 273 10 death death NN cord-334550-xb0alubj 273 11 toll toll NN cord-334550-xb0alubj 273 12 to to IN cord-334550-xb0alubj 273 13 4632 4632 CD cord-334550-xb0alubj 273 14 with with IN cord-334550-xb0alubj 273 15 a a DT cord-334550-xb0alubj 273 16 50 50 CD cord-334550-xb0alubj 273 17 % % NN cord-334550-xb0alubj 273 18 spike spike NN cord-334550-xb0alubj 273 19 in in IN cord-334550-xb0alubj 273 20 fatality fatality NN cord-334550-xb0alubj 273 21 figures figure NNS cord-334550-xb0alubj 273 22 . . . cord-334550-xb0alubj 274 1 11 11 CD cord-334550-xb0alubj 275 1 Such such JJ cord-334550-xb0alubj 275 2 discrepancies discrepancy NNS cord-334550-xb0alubj 275 3 may may MD cord-334550-xb0alubj 275 4 arise arise VB cord-334550-xb0alubj 275 5 because because IN cord-334550-xb0alubj 275 6 the the DT cord-334550-xb0alubj 275 7 official official JJ cord-334550-xb0alubj 275 8 count count NN cord-334550-xb0alubj 275 9 considers consider VBZ cord-334550-xb0alubj 275 10 only only RB cord-334550-xb0alubj 275 11 the the DT cord-334550-xb0alubj 275 12 hospital hospital NN cord-334550-xb0alubj 275 13 deaths death NNS cord-334550-xb0alubj 275 14 , , , cord-334550-xb0alubj 275 15 while while IN cord-334550-xb0alubj 275 16 majority majority NN cord-334550-xb0alubj 275 17 of of IN cord-334550-xb0alubj 275 18 the the DT cord-334550-xb0alubj 275 19 deaths death NNS cord-334550-xb0alubj 275 20 still still RB cord-334550-xb0alubj 275 21 happen happen VB cord-334550-xb0alubj 275 22 at at IN cord-334550-xb0alubj 275 23 home home NN cord-334550-xb0alubj 275 24 . . . cord-334550-xb0alubj 276 1 Also also RB cord-334550-xb0alubj 276 2 , , , cord-334550-xb0alubj 276 3 death death NN cord-334550-xb0alubj 276 4 due due IN cord-334550-xb0alubj 276 5 to to IN cord-334550-xb0alubj 276 6 COVID-19 COVID-19 NNP cord-334550-xb0alubj 276 7 may may MD cord-334550-xb0alubj 276 8 not not RB cord-334550-xb0alubj 276 9 be be VB cord-334550-xb0alubj 276 10 reported report VBN cord-334550-xb0alubj 276 11 in in IN cord-334550-xb0alubj 276 12 presence presence NN cord-334550-xb0alubj 276 13 of of IN cord-334550-xb0alubj 276 14 other other JJ cord-334550-xb0alubj 276 15 comorbidities comorbiditie NNS cord-334550-xb0alubj 276 16 . . . cord-334550-xb0alubj 277 1 Tracking tracking NN cord-334550-xb0alubj 277 2 deaths death NNS cord-334550-xb0alubj 277 3 is be VBZ cord-334550-xb0alubj 277 4 far far RB cord-334550-xb0alubj 277 5 more more RBR cord-334550-xb0alubj 277 6 reliable reliable JJ cord-334550-xb0alubj 277 7 than than IN cord-334550-xb0alubj 277 8 cases case NNS cord-334550-xb0alubj 277 9 , , , cord-334550-xb0alubj 277 10 which which WDT cord-334550-xb0alubj 277 11 are be VBP cord-334550-xb0alubj 277 12 significantly significantly RB cord-334550-xb0alubj 277 13 affected affect VBN cord-334550-xb0alubj 277 14 by by IN cord-334550-xb0alubj 277 15 testing test VBG cord-334550-xb0alubj 277 16 bias bias NN cord-334550-xb0alubj 277 17 . . . cord-334550-xb0alubj 278 1 Roughly roughly RB cord-334550-xb0alubj 278 2 , , , cord-334550-xb0alubj 278 3 86 86 CD cord-334550-xb0alubj 278 4 % % NN cord-334550-xb0alubj 278 5 of of IN cord-334550-xb0alubj 278 6 the the DT cord-334550-xb0alubj 278 7 COVID-19 covid-19 JJ cord-334550-xb0alubj 278 8 patients patient NNS cord-334550-xb0alubj 278 9 are be VBP cord-334550-xb0alubj 278 10 asymptomatic asymptomatic JJ cord-334550-xb0alubj 278 11 who who WP cord-334550-xb0alubj 278 12 hardly hardly RB cord-334550-xb0alubj 278 13 get get VBP cord-334550-xb0alubj 278 14 tested test VBN cord-334550-xb0alubj 278 15 and and CC cord-334550-xb0alubj 278 16 serve serve VB cord-334550-xb0alubj 278 17 as as IN cord-334550-xb0alubj 278 18 potential potential JJ cord-334550-xb0alubj 278 19 source source NN cord-334550-xb0alubj 278 20 for for IN cord-334550-xb0alubj 278 21 transmission transmission NN cord-334550-xb0alubj 278 22 of of IN cord-334550-xb0alubj 278 23 infection infection NN cord-334550-xb0alubj 278 24 . . . cord-334550-xb0alubj 279 1 In in IN cord-334550-xb0alubj 279 2 a a DT cord-334550-xb0alubj 279 3 densely densely RB cord-334550-xb0alubj 279 4 populated populated JJ cord-334550-xb0alubj 279 5 country country NN cord-334550-xb0alubj 279 6 like like IN cord-334550-xb0alubj 279 7 India India NNP cord-334550-xb0alubj 279 8 , , , cord-334550-xb0alubj 279 9 mass mass NN cord-334550-xb0alubj 279 10 screening screening NN cord-334550-xb0alubj 279 11 of of IN cord-334550-xb0alubj 279 12 population population NN cord-334550-xb0alubj 279 13 for for IN cord-334550-xb0alubj 279 14 COVID-19 COVID-19 NNP cord-334550-xb0alubj 279 15 is be VBZ cord-334550-xb0alubj 279 16 not not RB cord-334550-xb0alubj 279 17 feasible feasible JJ cord-334550-xb0alubj 279 18 . . . cord-334550-xb0alubj 280 1 So so RB cord-334550-xb0alubj 280 2 there there EX cord-334550-xb0alubj 280 3 are be VBP cord-334550-xb0alubj 280 4 chances chance NNS cord-334550-xb0alubj 280 5 that that IN cord-334550-xb0alubj 280 6 India India NNP cord-334550-xb0alubj 280 7 might may MD cord-334550-xb0alubj 280 8 be be VB cord-334550-xb0alubj 280 9 missing miss VBG cord-334550-xb0alubj 280 10 some some DT cord-334550-xb0alubj 280 11 deaths death NNS cord-334550-xb0alubj 280 12 and and CC cord-334550-xb0alubj 280 13 not not RB cord-334550-xb0alubj 280 14 diagnosing diagnose VBG cord-334550-xb0alubj 280 15 every every DT cord-334550-xb0alubj 280 16 case case NN cord-334550-xb0alubj 280 17 correctly correctly RB cord-334550-xb0alubj 280 18 . . . cord-334550-xb0alubj 281 1 However however RB cord-334550-xb0alubj 281 2 , , , cord-334550-xb0alubj 281 3 considering consider VBG cord-334550-xb0alubj 281 4 the the DT cord-334550-xb0alubj 281 5 magnitude magnitude NN cord-334550-xb0alubj 281 6 of of IN cord-334550-xb0alubj 281 7 the the DT cord-334550-xb0alubj 281 8 pandemic pandemic NN cord-334550-xb0alubj 281 9 , , , cord-334550-xb0alubj 281 10 India India NNP cord-334550-xb0alubj 281 11 has have VBZ cord-334550-xb0alubj 281 12 ramped ramp VBN cord-334550-xb0alubj 281 13 - - HYPH cord-334550-xb0alubj 281 14 up up RP cord-334550-xb0alubj 281 15 the the DT cord-334550-xb0alubj 281 16 testing testing NN cord-334550-xb0alubj 281 17 capacity capacity NN cord-334550-xb0alubj 281 18 with with IN cord-334550-xb0alubj 281 19 nearly nearly RB cord-334550-xb0alubj 281 20 250,000 250,000 CD cord-334550-xb0alubj 281 21 samples sample NNS cord-334550-xb0alubj 281 22 being be VBG cord-334550-xb0alubj 281 23 screened screen VBN cord-334550-xb0alubj 281 24 and and CC cord-334550-xb0alubj 281 25 over over IN cord-334550-xb0alubj 281 26 20,000 20,000 CD cord-334550-xb0alubj 281 27 active active JJ cord-334550-xb0alubj 281 28 cases case NNS cord-334550-xb0alubj 281 29 being be VBG cord-334550-xb0alubj 281 30 detected detect VBN cord-334550-xb0alubj 281 31 daily daily RB cord-334550-xb0alubj 281 32 . . . cord-334550-xb0alubj 282 1 6 6 CD cord-334550-xb0alubj 283 1 Still still RB cord-334550-xb0alubj 283 2 , , , cord-334550-xb0alubj 283 3 the the DT cord-334550-xb0alubj 283 4 fatality fatality NN cord-334550-xb0alubj 283 5 rate rate NN cord-334550-xb0alubj 283 6 in in IN cord-334550-xb0alubj 283 7 Indian indian JJ cord-334550-xb0alubj 283 8 cases case NNS cord-334550-xb0alubj 283 9 is be VBZ cord-334550-xb0alubj 283 10 low low JJ cord-334550-xb0alubj 283 11 and and CC cord-334550-xb0alubj 283 12 none none NN cord-334550-xb0alubj 283 13 has have VBZ cord-334550-xb0alubj 283 14 got get VBN cord-334550-xb0alubj 283 15 a a DT cord-334550-xb0alubj 283 16 definite definite JJ cord-334550-xb0alubj 283 17 answer answer NN cord-334550-xb0alubj 283 18 for for IN cord-334550-xb0alubj 283 19 that that DT cord-334550-xb0alubj 283 20 . . . cord-334550-xb0alubj 284 1 While while IN cord-334550-xb0alubj 284 2 this this DT cord-334550-xb0alubj 284 3 apparent apparent JJ cord-334550-xb0alubj 284 4 protection protection NN cord-334550-xb0alubj 284 5 among among IN cord-334550-xb0alubj 284 6 Indians Indians NNPS cord-334550-xb0alubj 284 7 is be VBZ cord-334550-xb0alubj 284 8 largely largely RB cord-334550-xb0alubj 284 9 attributed attribute VBN cord-334550-xb0alubj 284 10 to to IN cord-334550-xb0alubj 284 11 non non JJ cord-334550-xb0alubj 284 12 - - JJ cord-334550-xb0alubj 284 13 heritable heritable JJ cord-334550-xb0alubj 284 14 influences influence NNS cord-334550-xb0alubj 284 15 as as IN cord-334550-xb0alubj 284 16 discussed discuss VBN cord-334550-xb0alubj 284 17 earlier early RBR cord-334550-xb0alubj 284 18 , , , cord-334550-xb0alubj 284 19 a a DT cord-334550-xb0alubj 284 20 safe safe JJ cord-334550-xb0alubj 284 21 and and CC cord-334550-xb0alubj 284 22 effective effective JJ cord-334550-xb0alubj 284 23 vaccine vaccine NN cord-334550-xb0alubj 284 24 against against IN cord-334550-xb0alubj 284 25 SARS SARS NNP cord-334550-xb0alubj 284 26 - - HYPH cord-334550-xb0alubj 284 27 CoV-2 CoV-2 NNP cord-334550-xb0alubj 284 28 can can MD cord-334550-xb0alubj 284 29 reduce reduce VB cord-334550-xb0alubj 284 30 disease disease NN cord-334550-xb0alubj 284 31 severity severity NN cord-334550-xb0alubj 284 32 , , , cord-334550-xb0alubj 284 33 control control NN cord-334550-xb0alubj 284 34 transmission transmission NN cord-334550-xb0alubj 284 35 , , , cord-334550-xb0alubj 284 36 and and CC cord-334550-xb0alubj 284 37 prevent prevent VB cord-334550-xb0alubj 284 38 future future JJ cord-334550-xb0alubj 284 39 infections infection NNS cord-334550-xb0alubj 284 40 across across IN cord-334550-xb0alubj 284 41 all all DT cord-334550-xb0alubj 284 42 populations population NNS cord-334550-xb0alubj 284 43 . . . cord-334550-xb0alubj 285 1 Vaccines vaccine NNS cord-334550-xb0alubj 285 2 function function VBP cord-334550-xb0alubj 285 3 by by IN cord-334550-xb0alubj 285 4 inducing induce VBG cord-334550-xb0alubj 285 5 both both DT cord-334550-xb0alubj 285 6 arms arm NNS cord-334550-xb0alubj 285 7 of of IN cord-334550-xb0alubj 285 8 the the DT cord-334550-xb0alubj 285 9 adaptive adaptive JJ cord-334550-xb0alubj 285 10 immune immune JJ cord-334550-xb0alubj 285 11 response response NN cord-334550-xb0alubj 285 12 : : : cord-334550-xb0alubj 285 13 humoral humoral JJ cord-334550-xb0alubj 285 14 immunity immunity NN cord-334550-xb0alubj 285 15 ( ( -LRB- cord-334550-xb0alubj 285 16 producing produce VBG cord-334550-xb0alubj 285 17 neutralizing neutralize VBG cord-334550-xb0alubj 285 18 antibodies antibody NNS cord-334550-xb0alubj 285 19 that that WDT cord-334550-xb0alubj 285 20 prevent prevent VBP cord-334550-xb0alubj 285 21 virus virus NN cord-334550-xb0alubj 285 22 attachment attachment NN cord-334550-xb0alubj 285 23 ) ) -RRB- cord-334550-xb0alubj 285 24 and and CC cord-334550-xb0alubj 285 25 cell cell NN cord-334550-xb0alubj 285 26 - - HYPH cord-334550-xb0alubj 285 27 mediated mediate VBN cord-334550-xb0alubj 285 28 immunity immunity NN cord-334550-xb0alubj 285 29 ( ( -LRB- cord-334550-xb0alubj 285 30 activating activate VBG cord-334550-xb0alubj 285 31 antigen antigen NN cord-334550-xb0alubj 285 32 presenting present VBG cord-334550-xb0alubj 285 33 cells cell NNS cord-334550-xb0alubj 285 34 , , , cord-334550-xb0alubj 285 35 T t NN cord-334550-xb0alubj 285 36 - - HYPH cord-334550-xb0alubj 285 37 cells cell NNS cord-334550-xb0alubj 285 38 , , , cord-334550-xb0alubj 285 39 and and CC cord-334550-xb0alubj 285 40 NK NK NNP cord-334550-xb0alubj 285 41 cells cell NNS cord-334550-xb0alubj 285 42 that that WDT cord-334550-xb0alubj 285 43 recognize recognize VBP cord-334550-xb0alubj 285 44 and and CC cord-334550-xb0alubj 285 45 kill kill VBP cord-334550-xb0alubj 285 46 virus virus NN cord-334550-xb0alubj 285 47 - - HYPH cord-334550-xb0alubj 285 48 infected infect VBN cord-334550-xb0alubj 285 49 cells cell NNS cord-334550-xb0alubj 285 50 ) ) -RRB- cord-334550-xb0alubj 286 1 ( ( -LRB- cord-334550-xb0alubj 286 2 Mukherjee Mukherjee NNP cord-334550-xb0alubj 286 3 , , , cord-334550-xb0alubj 286 4 2020 2020 CD cord-334550-xb0alubj 286 5 ) ) -RRB- cord-334550-xb0alubj 286 6 . . . cord-334550-xb0alubj 287 1 There there EX cord-334550-xb0alubj 287 2 are be VBP cord-334550-xb0alubj 287 3 currently currently RB cord-334550-xb0alubj 287 4 ten ten CD cord-334550-xb0alubj 287 5 vaccines vaccine NNS cord-334550-xb0alubj 287 6 undergoing undergo VBG cord-334550-xb0alubj 287 7 clinical clinical JJ cord-334550-xb0alubj 287 8 trials trial NNS cord-334550-xb0alubj 287 9 against against IN cord-334550-xb0alubj 287 10 COVID-19 COVID-19 NNP cord-334550-xb0alubj 287 11 based base VBN cord-334550-xb0alubj 287 12 on on IN cord-334550-xb0alubj 287 13 several several JJ cord-334550-xb0alubj 287 14 technologies technology NNS cord-334550-xb0alubj 287 15 , , , cord-334550-xb0alubj 287 16 such such JJ cord-334550-xb0alubj 287 17 as as IN cord-334550-xb0alubj 287 18 , , , cord-334550-xb0alubj 287 19 live live VBP cord-334550-xb0alubj 287 20 attenuated attenuated JJ cord-334550-xb0alubj 287 21 , , , cord-334550-xb0alubj 287 22 inactivated inactivate VBN cord-334550-xb0alubj 287 23 , , , cord-334550-xb0alubj 287 24 mRNA mrna NN cord-334550-xb0alubj 287 25 , , , cord-334550-xb0alubj 287 26 DNA DNA NNP cord-334550-xb0alubj 287 27 , , , cord-334550-xb0alubj 287 28 viral viral JJ cord-334550-xb0alubj 287 29 vector vector NN cord-334550-xb0alubj 287 30 , , , cord-334550-xb0alubj 287 31 and and CC cord-334550-xb0alubj 287 32 peptide peptide NN cord-334550-xb0alubj 287 33 subunit subunit NN cord-334550-xb0alubj 287 34 based base VBN cord-334550-xb0alubj 287 35 platforms platform NNS cord-334550-xb0alubj 287 36 ( ( -LRB- cord-334550-xb0alubj 287 37 Mullard Mullard NNP cord-334550-xb0alubj 287 38 , , , cord-334550-xb0alubj 287 39 2020 2020 CD cord-334550-xb0alubj 287 40 ) ) -RRB- cord-334550-xb0alubj 287 41 . . . cord-334550-xb0alubj 288 1 A a DT cord-334550-xb0alubj 288 2 strong strong JJ cord-334550-xb0alubj 288 3 global global JJ cord-334550-xb0alubj 288 4 vaccination vaccination NN cord-334550-xb0alubj 288 5 program program NN cord-334550-xb0alubj 288 6 with with IN cord-334550-xb0alubj 288 7 equitable equitable JJ cord-334550-xb0alubj 288 8 distribution distribution NN cord-334550-xb0alubj 288 9 of of IN cord-334550-xb0alubj 288 10 promising promising JJ cord-334550-xb0alubj 288 11 vaccine vaccine NN cord-334550-xb0alubj 288 12 candidates candidate NNS cord-334550-xb0alubj 288 13 to to IN cord-334550-xb0alubj 288 14 all all DT cord-334550-xb0alubj 288 15 affected affect VBN cord-334550-xb0alubj 288 16 regions region NNS cord-334550-xb0alubj 288 17 is be VBZ cord-334550-xb0alubj 288 18 needed need VBN cord-334550-xb0alubj 288 19 to to TO cord-334550-xb0alubj 288 20 tackle tackle VB cord-334550-xb0alubj 288 21 the the DT cord-334550-xb0alubj 288 22 pandemic pandemic NN cord-334550-xb0alubj 288 23 . . . cord-334550-xb0alubj 289 1 This this DT cord-334550-xb0alubj 289 2 perspective perspective NN cord-334550-xb0alubj 289 3 puts put VBZ cord-334550-xb0alubj 289 4 forward forward RB cord-334550-xb0alubj 289 5 several several JJ cord-334550-xb0alubj 289 6 hypotheses hypothesis NNS cord-334550-xb0alubj 289 7 which which WDT cord-334550-xb0alubj 289 8 may may MD cord-334550-xb0alubj 289 9 explain explain VB cord-334550-xb0alubj 289 10 individual individual JJ cord-334550-xb0alubj 289 11 and and CC cord-334550-xb0alubj 289 12 population population NN cord-334550-xb0alubj 289 13 susceptibility susceptibility NN cord-334550-xb0alubj 289 14 to to IN cord-334550-xb0alubj 289 15 COVID-19 covid-19 VB cord-334550-xb0alubj 289 16 which which WDT cord-334550-xb0alubj 289 17 in in IN cord-334550-xb0alubj 289 18 turn turn NN cord-334550-xb0alubj 289 19 , , , cord-334550-xb0alubj 289 20 may may MD cord-334550-xb0alubj 289 21 help help VB cord-334550-xb0alubj 289 22 prioritize prioritize VB cord-334550-xb0alubj 289 23 vaccination vaccination NN cord-334550-xb0alubj 289 24 in in IN cord-334550-xb0alubj 289 25 high high JJ cord-334550-xb0alubj 289 26 risk risk NN cord-334550-xb0alubj 289 27 individuals individual NNS cord-334550-xb0alubj 289 28 and and CC cord-334550-xb0alubj 289 29 groups group NNS cord-334550-xb0alubj 289 30 , , , cord-334550-xb0alubj 289 31 and and CC cord-334550-xb0alubj 289 32 thus thus RB cord-334550-xb0alubj 289 33 reduce reduce VB cord-334550-xb0alubj 289 34 morbidity morbidity NN cord-334550-xb0alubj 289 35 and and CC cord-334550-xb0alubj 289 36 mortality mortality NN cord-334550-xb0alubj 289 37 across across IN cord-334550-xb0alubj 289 38 populations population NNS cord-334550-xb0alubj 289 39 . . . cord-334550-xb0alubj 290 1 Whether whether IN cord-334550-xb0alubj 290 2 the the DT cord-334550-xb0alubj 290 3 above above JJ cord-334550-xb0alubj 290 4 factors factor NNS cord-334550-xb0alubj 290 5 generate generate VBP cord-334550-xb0alubj 290 6 sufficient sufficient JJ cord-334550-xb0alubj 290 7 evidence evidence NN cord-334550-xb0alubj 290 8 to to TO cord-334550-xb0alubj 290 9 provide provide VB cord-334550-xb0alubj 290 10 satisfactory satisfactory JJ cord-334550-xb0alubj 290 11 explanation explanation NN cord-334550-xb0alubj 290 12 for for IN cord-334550-xb0alubj 290 13 their -PRON- PRP$ cord-334550-xb0alubj 290 14 apparent apparent JJ cord-334550-xb0alubj 290 15 protective protective JJ cord-334550-xb0alubj 290 16 effects effect NNS cord-334550-xb0alubj 290 17 on on IN cord-334550-xb0alubj 290 18 Indian indian JJ cord-334550-xb0alubj 290 19 population population NN cord-334550-xb0alubj 290 20 during during IN cord-334550-xb0alubj 290 21 COVID-19 COVID-19 NNP cord-334550-xb0alubj 290 22 pandemic pandemic NN cord-334550-xb0alubj 290 23 , , , cord-334550-xb0alubj 290 24 will will MD cord-334550-xb0alubj 290 25 be be VB cord-334550-xb0alubj 290 26 clear clear JJ cord-334550-xb0alubj 290 27 as as IN cord-334550-xb0alubj 290 28 the the DT cord-334550-xb0alubj 290 29 situation situation NN cord-334550-xb0alubj 290 30 unfolds unfold VBZ cord-334550-xb0alubj 290 31 further further RB cord-334550-xb0alubj 290 32 . . . cord-334550-xb0alubj 291 1 The the DT cord-334550-xb0alubj 291 2 original original JJ cord-334550-xb0alubj 291 3 contributions contribution NNS cord-334550-xb0alubj 291 4 presented present VBN cord-334550-xb0alubj 291 5 in in IN cord-334550-xb0alubj 291 6 the the DT cord-334550-xb0alubj 291 7 study study NN cord-334550-xb0alubj 291 8 are be VBP cord-334550-xb0alubj 291 9 included include VBN cord-334550-xb0alubj 291 10 in in IN cord-334550-xb0alubj 291 11 the the DT cord-334550-xb0alubj 291 12 article article NN cord-334550-xb0alubj 291 13 / / SYM cord-334550-xb0alubj 291 14 supplementary supplementary JJ cord-334550-xb0alubj 291 15 material material NN cord-334550-xb0alubj 291 16 , , , cord-334550-xb0alubj 291 17 further further JJ cord-334550-xb0alubj 291 18 inquiries inquiry NNS cord-334550-xb0alubj 291 19 can can MD cord-334550-xb0alubj 291 20 be be VB cord-334550-xb0alubj 291 21 directed direct VBN cord-334550-xb0alubj 291 22 to to IN cord-334550-xb0alubj 291 23 the the DT cord-334550-xb0alubj 291 24 corresponding correspond VBG cord-334550-xb0alubj 291 25 author author NN cord-334550-xb0alubj 291 26 . . . cord-334550-xb0alubj 292 1 AS AS NNP cord-334550-xb0alubj 292 2 and and CC cord-334550-xb0alubj 292 3 RG RG NNP cord-334550-xb0alubj 292 4 : : : cord-334550-xb0alubj 292 5 conceptualization conceptualization NN cord-334550-xb0alubj 292 6 , , , cord-334550-xb0alubj 292 7 data datum NNS cord-334550-xb0alubj 292 8 curation curation NN cord-334550-xb0alubj 292 9 , , , cord-334550-xb0alubj 292 10 and and CC cord-334550-xb0alubj 292 11 methodology methodology NN cord-334550-xb0alubj 292 12 . . . cord-334550-xb0alubj 293 1 AS as IN cord-334550-xb0alubj 293 2 , , , cord-334550-xb0alubj 293 3 RG RG NNP cord-334550-xb0alubj 293 4 , , , cord-334550-xb0alubj 293 5 and and CC cord-334550-xb0alubj 293 6 VN VN NNP cord-334550-xb0alubj 293 7 : : : cord-334550-xb0alubj 293 8 supervision supervision NN cord-334550-xb0alubj 293 9 . . . cord-334550-xb0alubj 294 1 AS as IN cord-334550-xb0alubj 294 2 , , , cord-334550-xb0alubj 294 3 RG RG NNP cord-334550-xb0alubj 294 4 , , , cord-334550-xb0alubj 294 5 VN VN NNP cord-334550-xb0alubj 294 6 , , , cord-334550-xb0alubj 294 7 and and CC cord-334550-xb0alubj 294 8 SM sm NN cord-334550-xb0alubj 294 9 : : : cord-334550-xb0alubj 294 10 validation validation NN cord-334550-xb0alubj 294 11 , , , cord-334550-xb0alubj 294 12 and and CC cord-334550-xb0alubj 294 13 visualization visualization NN cord-334550-xb0alubj 294 14 . . . cord-334550-xb0alubj 295 1 AS AS NNP cord-334550-xb0alubj 295 2 and and CC cord-334550-xb0alubj 295 3 RG RG NNP cord-334550-xb0alubj 295 4 : : : cord-334550-xb0alubj 295 5 writing write VBG cord-334550-xb0alubj 295 6 -original -original JJ cord-334550-xb0alubj 295 7 draft draft NN cord-334550-xb0alubj 295 8 . . . cord-334550-xb0alubj 296 1 AS as IN cord-334550-xb0alubj 296 2 , , , cord-334550-xb0alubj 296 3 RG RG NNP cord-334550-xb0alubj 296 4 , , , cord-334550-xb0alubj 296 5 VN VN NNP cord-334550-xb0alubj 296 6 , , , cord-334550-xb0alubj 296 7 and and CC cord-334550-xb0alubj 296 8 SM sm NN cord-334550-xb0alubj 296 9 : : : cord-334550-xb0alubj 296 10 writing writing NN cord-334550-xb0alubj 296 11 -review -review : cord-334550-xb0alubj 296 12 and and CC cord-334550-xb0alubj 296 13 editing editing NN cord-334550-xb0alubj 296 14 . . . cord-334550-xb0alubj 297 1 All all DT cord-334550-xb0alubj 297 2 authors author NNS cord-334550-xb0alubj 297 3 contributed contribute VBD cord-334550-xb0alubj 297 4 to to IN cord-334550-xb0alubj 297 5 the the DT cord-334550-xb0alubj 297 6 article article NN cord-334550-xb0alubj 297 7 and and CC cord-334550-xb0alubj 297 8 approved approve VBD cord-334550-xb0alubj 297 9 the the DT cord-334550-xb0alubj 297 10 submitted submit VBN cord-334550-xb0alubj 297 11 version version NN cord-334550-xb0alubj 297 12 . . . cord-334550-xb0alubj 298 1 BCG BCG NNP cord-334550-xb0alubj 298 2 vaccination vaccination NN cord-334550-xb0alubj 298 3 protects protect VBZ cord-334550-xb0alubj 298 4 against against IN cord-334550-xb0alubj 298 5 experimental experimental JJ cord-334550-xb0alubj 298 6 viral viral JJ cord-334550-xb0alubj 298 7 infection infection NN cord-334550-xb0alubj 298 8 in in IN cord-334550-xb0alubj 298 9 humans human NNS cord-334550-xb0alubj 298 10 through through IN cord-334550-xb0alubj 298 11 the the DT cord-334550-xb0alubj 298 12 induction induction NN cord-334550-xb0alubj 298 13 of of IN cord-334550-xb0alubj 298 14 cytokines cytokine NNS cord-334550-xb0alubj 298 15 associated associate VBN cord-334550-xb0alubj 298 16 with with IN cord-334550-xb0alubj 298 17 trained train VBN cord-334550-xb0alubj 298 18 immunity immunity NN cord-334550-xb0alubj 298 19 Severe severe JJ cord-334550-xb0alubj 298 20 acute acute JJ cord-334550-xb0alubj 298 21 respiratory respiratory JJ cord-334550-xb0alubj 298 22 syndrome syndrome NN cord-334550-xb0alubj 298 23 coronavirus coronavirus NN cord-334550-xb0alubj 298 24 2 2 CD cord-334550-xb0alubj 298 25 ( ( -LRB- cord-334550-xb0alubj 298 26 SARS SARS NNP cord-334550-xb0alubj 298 27 - - HYPH cord-334550-xb0alubj 298 28 CoV-2 CoV-2 NNP cord-334550-xb0alubj 298 29 ) ) -RRB- cord-334550-xb0alubj 298 30 : : : cord-334550-xb0alubj 298 31 an an DT cord-334550-xb0alubj 298 32 overview overview NN cord-334550-xb0alubj 298 33 of of IN cord-334550-xb0alubj 298 34 viral viral JJ cord-334550-xb0alubj 298 35 structure structure NN cord-334550-xb0alubj 298 36 and and CC cord-334550-xb0alubj 298 37 host host NN cord-334550-xb0alubj 298 38 response response NN cord-334550-xb0alubj 298 39 Reporting report VBG cord-334550-xb0alubj 298 40 two two CD cord-334550-xb0alubj 298 41 SARS SARS NNP cord-334550-xb0alubj 298 42 - - HYPH cord-334550-xb0alubj 298 43 CoV-2 CoV-2 NNP cord-334550-xb0alubj 298 44 strains strain NNS cord-334550-xb0alubj 298 45 based base VBN cord-334550-xb0alubj 298 46 on on IN cord-334550-xb0alubj 298 47 a a DT cord-334550-xb0alubj 298 48 unique unique JJ cord-334550-xb0alubj 298 49 trinucleotide trinucleotide NNP cord-334550-xb0alubj 298 50 - - HYPH cord-334550-xb0alubj 298 51 bloc bloc NN cord-334550-xb0alubj 298 52 mutation mutation NN cord-334550-xb0alubj 298 53 and and CC cord-334550-xb0alubj 298 54 352 352 CD cord-334550-xb0alubj 298 55 their -PRON- PRP$ cord-334550-xb0alubj 298 56 potential potential JJ cord-334550-xb0alubj 298 57 pathogenic pathogenic JJ cord-334550-xb0alubj 298 58 difference difference NN cord-334550-xb0alubj 299 1 The the DT cord-334550-xb0alubj 299 2 novel novel JJ cord-334550-xb0alubj 299 3 coronavirus coronavirus NN cord-334550-xb0alubj 299 4 enigma enigma NN cord-334550-xb0alubj 299 5 : : : cord-334550-xb0alubj 299 6 phylogeny phylogeny NN cord-334550-xb0alubj 299 7 and and CC cord-334550-xb0alubj 299 8 mutation mutation NN cord-334550-xb0alubj 299 9 analyses analysis NNS cord-334550-xb0alubj 299 10 of of IN cord-334550-xb0alubj 299 11 SARS SARS NNP cord-334550-xb0alubj 299 12 - - HYPH cord-334550-xb0alubj 299 13 CoV-2 CoV-2 NNP cord-334550-xb0alubj 299 14 viruses virus NNS cord-334550-xb0alubj 299 15 circulating circulate VBG cord-334550-xb0alubj 299 16 in in IN cord-334550-xb0alubj 299 17 India India NNP cord-334550-xb0alubj 299 18 during during IN cord-334550-xb0alubj 299 19 early early JJ cord-334550-xb0alubj 299 20 2020 2020 CD cord-334550-xb0alubj 299 21 . . . cord-334550-xb0alubj 300 1 bioRxiv bioRxiv NNP cord-334550-xb0alubj 300 2 MicroRNA MicroRNA NNP cord-334550-xb0alubj 300 3 involvement involvement NN cord-334550-xb0alubj 300 4 in in IN cord-334550-xb0alubj 300 5 signaling signal VBG cord-334550-xb0alubj 300 6 pathways pathway NNS cord-334550-xb0alubj 300 7 during during IN cord-334550-xb0alubj 300 8 viral viral JJ cord-334550-xb0alubj 300 9 infection infection NN cord-334550-xb0alubj 300 10 . . . cord-334550-xb0alubj 301 1 Front Front NNP cord-334550-xb0alubj 301 2 Analysis Analysis NNP cord-334550-xb0alubj 301 3 of of IN cord-334550-xb0alubj 301 4 RNA RNA NNP cord-334550-xb0alubj 301 5 sequences sequence NNS cord-334550-xb0alubj 301 6 of of IN cord-334550-xb0alubj 301 7 3636 3636 CD cord-334550-xb0alubj 301 8 SARS SARS NNP cord-334550-xb0alubj 301 9 - - HYPH cord-334550-xb0alubj 301 10 CoV-2 CoV-2 NNP cord-334550-xb0alubj 301 11 collected collect VBD cord-334550-xb0alubj 301 12 from from IN cord-334550-xb0alubj 301 13 55 55 CD cord-334550-xb0alubj 301 14 countries country NNS cord-334550-xb0alubj 301 15 reveals reveal VBZ cord-334550-xb0alubj 301 16 selective selective JJ cord-334550-xb0alubj 301 17 sweep sweep NN cord-334550-xb0alubj 301 18 of of IN cord-334550-xb0alubj 301 19 one one CD cord-334550-xb0alubj 301 20 virus virus NN cord-334550-xb0alubj 301 21 type type NN cord-334550-xb0alubj 301 22 Human human JJ cord-334550-xb0alubj 301 23 immune immune JJ cord-334550-xb0alubj 301 24 system system NN cord-334550-xb0alubj 301 25 variation variation NN cord-334550-xb0alubj 301 26 Variation variation NN cord-334550-xb0alubj 301 27 in in IN cord-334550-xb0alubj 301 28 the the DT cord-334550-xb0alubj 301 29 human human JJ cord-334550-xb0alubj 301 30 immune immune NN cord-334550-xb0alubj 301 31 system system NN cord-334550-xb0alubj 301 32 is be VBZ cord-334550-xb0alubj 301 33 largely largely RB cord-334550-xb0alubj 301 34 driven drive VBN cord-334550-xb0alubj 301 35 by by IN cord-334550-xb0alubj 301 36 non non JJ cord-334550-xb0alubj 301 37 - - JJ cord-334550-xb0alubj 301 38 heritable heritable JJ cord-334550-xb0alubj 301 39 influences influence NNS cord-334550-xb0alubj 301 40 Distinct distinct JJ cord-334550-xb0alubj 301 41 viral viral JJ cord-334550-xb0alubj 301 42 clades clade NNS cord-334550-xb0alubj 301 43 of of IN cord-334550-xb0alubj 301 44 SARS SARS NNP cord-334550-xb0alubj 301 45 - - HYPH cord-334550-xb0alubj 301 46 CoV-2 CoV-2 NNP cord-334550-xb0alubj 301 47 : : : cord-334550-xb0alubj 301 48 implications implication NNS cord-334550-xb0alubj 301 49 for for IN cord-334550-xb0alubj 301 50 modeling modeling NN cord-334550-xb0alubj 301 51 of of IN cord-334550-xb0alubj 301 52 viral viral JJ cord-334550-xb0alubj 301 53 spread spread NN cord-334550-xb0alubj 301 54 ACE2 ACE2 NNP cord-334550-xb0alubj 301 55 polymorphisms polymorphism NNS cord-334550-xb0alubj 301 56 and and CC cord-334550-xb0alubj 301 57 individual individual JJ cord-334550-xb0alubj 301 58 susceptibility susceptibility NN cord-334550-xb0alubj 301 59 to to IN cord-334550-xb0alubj 301 60 SARS SARS NNP cord-334550-xb0alubj 301 61 - - HYPH cord-334550-xb0alubj 301 62 CoV-2 CoV-2 NNP cord-334550-xb0alubj 301 63 infection infection NN cord-334550-xb0alubj 301 64 : : : cord-334550-xb0alubj 301 65 insights insight NNS cord-334550-xb0alubj 301 66 from from IN cord-334550-xb0alubj 301 67 an an DT cord-334550-xb0alubj 301 68 in in IN cord-334550-xb0alubj 301 69 silico silico NN cord-334550-xb0alubj 301 70 study study NN cord-334550-xb0alubj 301 71 . . . cord-334550-xb0alubj 302 1 bioRxiv biorxiv RB cord-334550-xb0alubj 303 1 Structure structure NN cord-334550-xb0alubj 303 2 / / SYM cord-334550-xb0alubj 303 3 function function NN cord-334550-xb0alubj 303 4 of of IN cord-334550-xb0alubj 303 5 human human JJ cord-334550-xb0alubj 303 6 killer killer NN cord-334550-xb0alubj 303 7 cell cell NN cord-334550-xb0alubj 303 8 immunoglobulin immunoglobulin NN cord-334550-xb0alubj 303 9 - - HYPH cord-334550-xb0alubj 303 10 like like JJ cord-334550-xb0alubj 303 11 receptors receptor NNS cord-334550-xb0alubj 303 12 : : : cord-334550-xb0alubj 303 13 lessons lesson NNS cord-334550-xb0alubj 303 14 from from IN cord-334550-xb0alubj 303 15 polymorphisms polymorphism NNS cord-334550-xb0alubj 303 16 , , , cord-334550-xb0alubj 303 17 evolution evolution NN cord-334550-xb0alubj 303 18 , , , cord-334550-xb0alubj 303 19 crystal crystal NN cord-334550-xb0alubj 303 20 structures structure NNS cord-334550-xb0alubj 303 21 and and CC cord-334550-xb0alubj 303 22 mutations mutation NNS cord-334550-xb0alubj 303 23 Clinical clinical JJ cord-334550-xb0alubj 303 24 and and CC cord-334550-xb0alubj 303 25 immunological immunological JJ cord-334550-xb0alubj 303 26 features feature NNS cord-334550-xb0alubj 303 27 of of IN cord-334550-xb0alubj 303 28 severe severe JJ cord-334550-xb0alubj 303 29 and and CC cord-334550-xb0alubj 303 30 moderate moderate JJ cord-334550-xb0alubj 303 31 coronavirus coronavirus NN cord-334550-xb0alubj 303 32 disease disease NN cord-334550-xb0alubj 303 33 2019 2019 CD cord-334550-xb0alubj 304 1 Circulating circulate VBG cord-334550-xb0alubj 304 2 microRNAs microrna NNS cord-334550-xb0alubj 305 1 as as IN cord-334550-xb0alubj 305 2 potential potential JJ cord-334550-xb0alubj 305 3 biomarkers biomarker NNS cord-334550-xb0alubj 305 4 of of IN cord-334550-xb0alubj 305 5 infectious infectious JJ cord-334550-xb0alubj 305 6 disease disease NN cord-334550-xb0alubj 305 7 ImmVar ImmVar NNP cord-334550-xb0alubj 305 8 project project NN cord-334550-xb0alubj 305 9 : : : cord-334550-xb0alubj 305 10 insights insight NNS cord-334550-xb0alubj 305 11 and and CC cord-334550-xb0alubj 305 12 design design NN cord-334550-xb0alubj 305 13 considerations consideration NNS cord-334550-xb0alubj 305 14 for for IN cord-334550-xb0alubj 305 15 future future JJ cord-334550-xb0alubj 305 16 studies study NNS cord-334550-xb0alubj 305 17 of of IN cord-334550-xb0alubj 305 18 " " `` cord-334550-xb0alubj 305 19 healthy healthy JJ cord-334550-xb0alubj 305 20 " " '' cord-334550-xb0alubj 305 21 immune immune JJ cord-334550-xb0alubj 305 22 variation variation NN cord-334550-xb0alubj 305 23 Analysis analysis NN cord-334550-xb0alubj 305 24 of of IN cord-334550-xb0alubj 305 25 coronavirus coronavirus NN cord-334550-xb0alubj 305 26 temperature temperature NN cord-334550-xb0alubj 305 27 - - HYPH cord-334550-xb0alubj 305 28 sensitive sensitive JJ cord-334550-xb0alubj 305 29 mutants mutant NNS cord-334550-xb0alubj 305 30 reveals reveal VBZ cord-334550-xb0alubj 305 31 an an DT cord-334550-xb0alubj 305 32 interplay interplay NN cord-334550-xb0alubj 305 33 between between IN cord-334550-xb0alubj 305 34 the the DT cord-334550-xb0alubj 305 35 macrodomain macrodomain NN cord-334550-xb0alubj 305 36 and and CC cord-334550-xb0alubj 305 37 papain papain NN cord-334550-xb0alubj 305 38 - - HYPH cord-334550-xb0alubj 305 39 like like JJ cord-334550-xb0alubj 305 40 protease protease NN cord-334550-xb0alubj 305 41 impacting impact VBG cord-334550-xb0alubj 305 42 replication replication NN cord-334550-xb0alubj 305 43 and and CC cord-334550-xb0alubj 305 44 pathogenesis pathogenesis NN cord-334550-xb0alubj 305 45 Epidemiology epidemiology NN cord-334550-xb0alubj 305 46 of of IN cord-334550-xb0alubj 305 47 coronavirus coronavirus NN cord-334550-xb0alubj 305 48 disease disease NN cord-334550-xb0alubj 305 49 in in IN cord-334550-xb0alubj 305 50 Gansu Gansu NNP cord-334550-xb0alubj 305 51 Province Province NNP cord-334550-xb0alubj 305 52 , , , cord-334550-xb0alubj 305 53 China China NNP cord-334550-xb0alubj 305 54 , , , cord-334550-xb0alubj 305 55 2020 2020 CD cord-334550-xb0alubj 305 56 . . . cord-334550-xb0alubj 306 1 Emerg Emerg NNP cord-334550-xb0alubj 306 2 Could Could NNP cord-334550-xb0alubj 306 3 an an DT cord-334550-xb0alubj 306 4 unrelated unrelated JJ cord-334550-xb0alubj 306 5 live live JJ cord-334550-xb0alubj 306 6 attenuated attenuated JJ cord-334550-xb0alubj 306 7 vaccine vaccine NN cord-334550-xb0alubj 306 8 serve serve VBP cord-334550-xb0alubj 306 9 as as IN cord-334550-xb0alubj 306 10 a a DT cord-334550-xb0alubj 306 11 preventive preventive JJ cord-334550-xb0alubj 306 12 measure measure NN cord-334550-xb0alubj 306 13 to to TO cord-334550-xb0alubj 306 14 dampen dampen VB cord-334550-xb0alubj 306 15 septic septic JJ cord-334550-xb0alubj 306 16 inflammation inflammation NN cord-334550-xb0alubj 306 17 associated associate VBN cord-334550-xb0alubj 306 18 with with IN cord-334550-xb0alubj 306 19 COVID-19 covid-19 JJ cord-334550-xb0alubj 306 20 infection infection NN cord-334550-xb0alubj 306 21 ? ? . cord-334550-xb0alubj 307 1 mBio mbio NN cord-334550-xb0alubj 307 2 11 11 CD cord-334550-xb0alubj 307 3 Increased increase VBN cord-334550-xb0alubj 307 4 resistance resistance NN cord-334550-xb0alubj 307 5 to to IN cord-334550-xb0alubj 307 6 virus virus NN cord-334550-xb0alubj 307 7 infections infection NNS cord-334550-xb0alubj 307 8 of of IN cord-334550-xb0alubj 307 9 mice mouse NNS cord-334550-xb0alubj 307 10 inoculated inoculate VBN cord-334550-xb0alubj 307 11 with with IN cord-334550-xb0alubj 307 12 BCG BCG NNP cord-334550-xb0alubj 307 13 ( ( -LRB- cord-334550-xb0alubj 307 14 Bacillus Bacillus NNP cord-334550-xb0alubj 307 15 Calmette Calmette NNP cord-334550-xb0alubj 307 16 - - HYPH cord-334550-xb0alubj 307 17 Guérin Guérin NNP cord-334550-xb0alubj 307 18 ) ) -RRB- cord-334550-xb0alubj 307 19 Phylogenetic Phylogenetic NNP cord-334550-xb0alubj 307 20 network network NN cord-334550-xb0alubj 307 21 analysis analysis NN cord-334550-xb0alubj 307 22 of of IN cord-334550-xb0alubj 307 23 SARS SARS NNP cord-334550-xb0alubj 307 24 - - HYPH cord-334550-xb0alubj 307 25 CoV-2 CoV-2 NNP cord-334550-xb0alubj 307 26 genomes genome NNS cord-334550-xb0alubj 307 27 MMR MMR NNP cord-334550-xb0alubj 307 28 vaccine vaccine NN cord-334550-xb0alubj 307 29 appears appear VBZ cord-334550-xb0alubj 307 30 to to TO cord-334550-xb0alubj 307 31 confer confer VB cord-334550-xb0alubj 307 32 strong strong JJ cord-334550-xb0alubj 307 33 protection protection NN cord-334550-xb0alubj 307 34 from from IN cord-334550-xb0alubj 307 35 COVID-19 covid-19 JJ cord-334550-xb0alubj 307 36 : : : cord-334550-xb0alubj 307 37 few few JJ cord-334550-xb0alubj 307 38 deaths death NNS cord-334550-xb0alubj 307 39 from from IN cord-334550-xb0alubj 307 40 SARS SARS NNP cord-334550-xb0alubj 307 41 - - HYPH cord-334550-xb0alubj 307 42 CoV-2 CoV-2 NNP cord-334550-xb0alubj 307 43 in in IN cord-334550-xb0alubj 307 44 highly highly RB cord-334550-xb0alubj 307 45 vaccinated vaccinate VBN cord-334550-xb0alubj 307 46 populations population NNS cord-334550-xb0alubj 307 47 . . . cord-334550-xb0alubj 308 1 Researchgate Researchgate NNP cord-334550-xb0alubj 309 1 The the DT cord-334550-xb0alubj 309 2 genomic genomic JJ cord-334550-xb0alubj 309 3 variation variation NN cord-334550-xb0alubj 309 4 landscape landscape NN cord-334550-xb0alubj 309 5 of of IN cord-334550-xb0alubj 309 6 globally globally RB cord-334550-xb0alubj 309 7 - - HYPH cord-334550-xb0alubj 309 8 circulating circulate VBG cord-334550-xb0alubj 309 9 clades clade NNS cord-334550-xb0alubj 309 10 of of IN cord-334550-xb0alubj 309 11 SARS SARS NNP cord-334550-xb0alubj 309 12 - - HYPH cord-334550-xb0alubj 309 13 CoV-2 CoV-2 NNP cord-334550-xb0alubj 309 14 defines define VBZ cord-334550-xb0alubj 309 15 a a DT cord-334550-xb0alubj 309 16 genetic genetic JJ cord-334550-xb0alubj 309 17 barcoding barcoding NN cord-334550-xb0alubj 309 18 scheme scheme NN cord-334550-xb0alubj 309 19 . . . cord-334550-xb0alubj 310 1 bioRxiv biorxiv DT cord-334550-xb0alubj 310 2 Distribution distribution NN cord-334550-xb0alubj 310 3 of of IN cord-334550-xb0alubj 310 4 killer killer NN cord-334550-xb0alubj 310 5 cell cell NN cord-334550-xb0alubj 310 6 immunoglobulin immunoglobulin NN cord-334550-xb0alubj 310 7 - - HYPH cord-334550-xb0alubj 310 8 like like JJ cord-334550-xb0alubj 310 9 receptors receptor NNS cord-334550-xb0alubj 310 10 ( ( -LRB- cord-334550-xb0alubj 310 11 KIR KIR NNP cord-334550-xb0alubj 310 12 ) ) -RRB- cord-334550-xb0alubj 310 13 and and CC cord-334550-xb0alubj 310 14 their -PRON- PRP$ cord-334550-xb0alubj 310 15 HLA HLA NNP cord-334550-xb0alubj 310 16 - - HYPH cord-334550-xb0alubj 310 17 C C NNP cord-334550-xb0alubj 310 18 ligands ligand NNS cord-334550-xb0alubj 310 19 in in IN cord-334550-xb0alubj 310 20 two two CD cord-334550-xb0alubj 310 21 Iranian iranian JJ cord-334550-xb0alubj 310 22 populations population NNS cord-334550-xb0alubj 311 1 Structural structural JJ cord-334550-xb0alubj 311 2 variations variation NNS cord-334550-xb0alubj 311 3 in in IN cord-334550-xb0alubj 311 4 human human JJ cord-334550-xb0alubj 311 5 ACE2 ACE2 NNP cord-334550-xb0alubj 311 6 may may MD cord-334550-xb0alubj 311 7 influence influence VB cord-334550-xb0alubj 311 8 its -PRON- PRP$ cord-334550-xb0alubj 311 9 binding binding NN cord-334550-xb0alubj 311 10 with with IN cord-334550-xb0alubj 311 11 SARS SARS NNP cord-334550-xb0alubj 311 12 - - HYPH cord-334550-xb0alubj 311 13 CoV-2 CoV-2 NNP cord-334550-xb0alubj 311 14 spike spike NN cord-334550-xb0alubj 311 15 protein protein NN cord-334550-xb0alubj 311 16 ACE2 ACE2 NNP cord-334550-xb0alubj 311 17 receptor receptor NN cord-334550-xb0alubj 311 18 expression expression NN cord-334550-xb0alubj 311 19 and and CC cord-334550-xb0alubj 311 20 severe severe JJ cord-334550-xb0alubj 311 21 acute acute JJ cord-334550-xb0alubj 311 22 respiratory respiratory JJ cord-334550-xb0alubj 311 23 syndrome syndrome NN cord-334550-xb0alubj 311 24 coronavirus coronavirus NN cord-334550-xb0alubj 311 25 infection infection NN cord-334550-xb0alubj 312 1 depend depend VB cord-334550-xb0alubj 312 2 on on IN cord-334550-xb0alubj 312 3 differentiation differentiation NN cord-334550-xb0alubj 312 4 of of IN cord-334550-xb0alubj 312 5 human human JJ cord-334550-xb0alubj 312 6 airway airway NN cord-334550-xb0alubj 312 7 epithelia epithelia VBP cord-334550-xb0alubj 312 8 Large large JJ cord-334550-xb0alubj 312 9 scale scale NN cord-334550-xb0alubj 312 10 genomic genomic NN cord-334550-xb0alubj 312 11 analysis analysis NN cord-334550-xb0alubj 312 12 of of IN cord-334550-xb0alubj 312 13 3067 3067 CD cord-334550-xb0alubj 312 14 SARS SARS NNP cord-334550-xb0alubj 312 15 - - HYPH cord-334550-xb0alubj 312 16 CoV-2 CoV-2 NNP cord-334550-xb0alubj 312 17 genomes genome NNS cord-334550-xb0alubj 312 18 reveals reveal VBZ cord-334550-xb0alubj 312 19 a a DT cord-334550-xb0alubj 312 20 clonal clonal JJ cord-334550-xb0alubj 312 21 geo geo NN cord-334550-xb0alubj 312 22 - - HYPH cord-334550-xb0alubj 312 23 distribution distribution NN cord-334550-xb0alubj 312 24 and and CC cord-334550-xb0alubj 312 25 a a DT cord-334550-xb0alubj 312 26 rich rich JJ cord-334550-xb0alubj 312 27 genetic genetic JJ cord-334550-xb0alubj 312 28 variations variation NNS cord-334550-xb0alubj 312 29 of of IN cord-334550-xb0alubj 312 30 hotspots hotspot NNS cord-334550-xb0alubj 312 31 mutations mutation NNS cord-334550-xb0alubj 312 32 . . . cord-334550-xb0alubj 313 1 bioRxiv biorxiv RB cord-334550-xb0alubj 314 1 Vanilloid Vanilloid NNP cord-334550-xb0alubj 314 2 receptor receptor NN cord-334550-xb0alubj 314 3 1 1 CD cord-334550-xb0alubj 314 4 agonists agonist NNS cord-334550-xb0alubj 314 5 , , , cord-334550-xb0alubj 314 6 capsaicin capsaicin NN cord-334550-xb0alubj 314 7 and and CC cord-334550-xb0alubj 314 8 resiniferatoxin resiniferatoxin NNP cord-334550-xb0alubj 314 9 , , , cord-334550-xb0alubj 314 10 enhance enhance VB cord-334550-xb0alubj 314 11 MHC MHC NNP cord-334550-xb0alubj 314 12 class class NN cord-334550-xb0alubj 314 13 I i NN cord-334550-xb0alubj 314 14 - - HYPH cord-334550-xb0alubj 314 15 restricted restrict VBN cord-334550-xb0alubj 314 16 viral viral JJ cord-334550-xb0alubj 314 17 antigen antigen NN cord-334550-xb0alubj 314 18 presentation presentation NN cord-334550-xb0alubj 314 19 in in IN cord-334550-xb0alubj 314 20 virus virus NN cord-334550-xb0alubj 314 21 - - HYPH cord-334550-xb0alubj 314 22 infected infect VBN cord-334550-xb0alubj 314 23 dendritic dendritic JJ cord-334550-xb0alubj 314 24 cells cell NNS cord-334550-xb0alubj 314 25 Analysis Analysis NNP cord-334550-xb0alubj 314 26 of of IN cord-334550-xb0alubj 314 27 factors factor NNS cord-334550-xb0alubj 314 28 associated associate VBN cord-334550-xb0alubj 314 29 with with IN cord-334550-xb0alubj 314 30 disease disease NN cord-334550-xb0alubj 314 31 outcomes outcome NNS cord-334550-xb0alubj 314 32 in in IN cord-334550-xb0alubj 314 33 hospitalized hospitalize VBN cord-334550-xb0alubj 314 34 patients patient NNS cord-334550-xb0alubj 314 35 with with IN cord-334550-xb0alubj 314 36 2019 2019 CD cord-334550-xb0alubj 314 37 novel novel JJ cord-334550-xb0alubj 314 38 coronavirus coronavirus NN cord-334550-xb0alubj 314 39 disease disease NN cord-334550-xb0alubj 314 40 Bioactive Bioactive NNP cord-334550-xb0alubj 314 41 compounds compound NNS cord-334550-xb0alubj 314 42 and and CC cord-334550-xb0alubj 314 43 bioactivities bioactivitie NNS cord-334550-xb0alubj 314 44 of of IN cord-334550-xb0alubj 314 45 ginger ginger NNP cord-334550-xb0alubj 314 46 Inhibition Inhibition NNP cord-334550-xb0alubj 314 47 of of IN cord-334550-xb0alubj 314 48 influenza influenza NN cord-334550-xb0alubj 314 49 virus virus NN cord-334550-xb0alubj 314 50 replication replication NN cord-334550-xb0alubj 314 51 by by IN cord-334550-xb0alubj 314 52 targeting target VBG cord-334550-xb0alubj 314 53 broad broad JJ cord-334550-xb0alubj 314 54 host host NN cord-334550-xb0alubj 314 55 cell cell NN cord-334550-xb0alubj 314 56 pathway pathway NN cord-334550-xb0alubj 314 57 Defining define VBG cord-334550-xb0alubj 314 58 genetic genetic JJ cord-334550-xb0alubj 314 59 architecture architecture NN cord-334550-xb0alubj 314 60 of of IN cord-334550-xb0alubj 314 61 the the DT cord-334550-xb0alubj 314 62 populations population NNS cord-334550-xb0alubj 314 63 in in IN cord-334550-xb0alubj 314 64 the the DT cord-334550-xb0alubj 314 65 Indian indian JJ cord-334550-xb0alubj 314 66 subcontinent subcontinent NN cord-334550-xb0alubj 314 67 : : : cord-334550-xb0alubj 314 68 impact impact NN cord-334550-xb0alubj 314 69 of of IN cord-334550-xb0alubj 314 70 human human JJ cord-334550-xb0alubj 314 71 leukocyte leukocyte NN cord-334550-xb0alubj 314 72 antigen antigen NN cord-334550-xb0alubj 314 73 diversity diversity NN cord-334550-xb0alubj 314 74 studies study NNS cord-334550-xb0alubj 314 75 Geographic Geographic NNP cord-334550-xb0alubj 314 76 and and CC cord-334550-xb0alubj 314 77 genomic genomic JJ cord-334550-xb0alubj 314 78 distribution distribution NN cord-334550-xb0alubj 314 79 of of IN cord-334550-xb0alubj 314 80 SARS SARS NNP cord-334550-xb0alubj 314 81 - - HYPH cord-334550-xb0alubj 314 82 CoV-2 CoV-2 NNP cord-334550-xb0alubj 314 83 mutations mutation NNS cord-334550-xb0alubj 315 1 The the DT cord-334550-xb0alubj 315 2 extensive extensive JJ cord-334550-xb0alubj 315 3 polymorphism polymorphism NN cord-334550-xb0alubj 315 4 of of IN cord-334550-xb0alubj 315 5 KIR KIR NNP cord-334550-xb0alubj 315 6 genes gene NNS cord-334550-xb0alubj 315 7 Correlation Correlation NNP cord-334550-xb0alubj 315 8 between between IN cord-334550-xb0alubj 315 9 universal universal JJ cord-334550-xb0alubj 315 10 BCG BCG NNP cord-334550-xb0alubj 315 11 vaccination vaccination NN cord-334550-xb0alubj 315 12 policy policy NN cord-334550-xb0alubj 315 13 and and CC cord-334550-xb0alubj 315 14 reduced reduce VBN cord-334550-xb0alubj 315 15 morbidity morbidity NN cord-334550-xb0alubj 315 16 and and CC cord-334550-xb0alubj 315 17 mortality mortality NN cord-334550-xb0alubj 315 18 for for IN cord-334550-xb0alubj 315 19 COVID-19 covid-19 NN cord-334550-xb0alubj 315 20 : : : cord-334550-xb0alubj 315 21 an an DT cord-334550-xb0alubj 315 22 epidemiological epidemiological JJ cord-334550-xb0alubj 315 23 study study NN cord-334550-xb0alubj 315 24 . . . cord-334550-xb0alubj 316 1 medRxiv medRxiv NNS cord-334550-xb0alubj 316 2 A a DT cord-334550-xb0alubj 316 3 review review NN cord-334550-xb0alubj 316 4 on on IN cord-334550-xb0alubj 316 5 antibacterial antibacterial JJ cord-334550-xb0alubj 316 6 , , , cord-334550-xb0alubj 316 7 antiviral antiviral JJ cord-334550-xb0alubj 316 8 , , , cord-334550-xb0alubj 316 9 and and CC cord-334550-xb0alubj 316 10 antifungal antifungal JJ cord-334550-xb0alubj 316 11 activity activity NN cord-334550-xb0alubj 316 12 of of IN cord-334550-xb0alubj 316 13 curcumin curcumin NN cord-334550-xb0alubj 316 14 Clinical clinical JJ cord-334550-xb0alubj 316 15 role role NN cord-334550-xb0alubj 316 16 of of IN cord-334550-xb0alubj 316 17 human human JJ cord-334550-xb0alubj 316 18 leukocyte leukocyte NN cord-334550-xb0alubj 316 19 antigen antigen NN cord-334550-xb0alubj 316 20 in in IN cord-334550-xb0alubj 316 21 health health NN cord-334550-xb0alubj 316 22 and and CC cord-334550-xb0alubj 316 23 disease disease NN cord-334550-xb0alubj 316 24 Global global JJ cord-334550-xb0alubj 316 25 efforts effort NNS cord-334550-xb0alubj 316 26 on on IN cord-334550-xb0alubj 316 27 vaccines vaccine NNS cord-334550-xb0alubj 316 28 for for IN cord-334550-xb0alubj 316 29 COVID-19 covid-19 NN cord-334550-xb0alubj 316 30 : : : cord-334550-xb0alubj 316 31 since since IN cord-334550-xb0alubj 316 32 , , , cord-334550-xb0alubj 316 33 sooner soon RBR cord-334550-xb0alubj 316 34 or or CC cord-334550-xb0alubj 316 35 later later RBR cord-334550-xb0alubj 316 36 , , , cord-334550-xb0alubj 316 37 we -PRON- PRP cord-334550-xb0alubj 316 38 all all DT cord-334550-xb0alubj 316 39 will will MD cord-334550-xb0alubj 316 40 catch catch VB cord-334550-xb0alubj 316 41 the the DT cord-334550-xb0alubj 316 42 coronavirus coronavirus NN cord-334550-xb0alubj 317 1 COVID-19 covid-19 VB cord-334550-xb0alubj 318 1 vaccine vaccine NNP cord-334550-xb0alubj 318 2 development development NNP cord-334550-xb0alubj 318 3 pipeline pipeline NN cord-334550-xb0alubj 318 4 gears gear VBZ cord-334550-xb0alubj 318 5 up up RP cord-334550-xb0alubj 318 6 Human human JJ cord-334550-xb0alubj 318 7 leukocyte leukocyte NN cord-334550-xb0alubj 318 8 antigen antigen NN cord-334550-xb0alubj 318 9 susceptibility susceptibility NN cord-334550-xb0alubj 318 10 map map NN cord-334550-xb0alubj 318 11 for for IN cord-334550-xb0alubj 318 12 severe severe JJ cord-334550-xb0alubj 318 13 acute acute JJ cord-334550-xb0alubj 318 14 respiratory respiratory JJ cord-334550-xb0alubj 318 15 syndrome syndrome NN cord-334550-xb0alubj 318 16 coronavirus coronavirus NN cord-334550-xb0alubj 318 17 2 2 CD cord-334550-xb0alubj 318 18 Distinct distinct JJ cord-334550-xb0alubj 318 19 diversity diversity NN cord-334550-xb0alubj 318 20 of of IN cord-334550-xb0alubj 318 21 KIR KIR NNP cord-334550-xb0alubj 318 22 genes gene NNS cord-334550-xb0alubj 318 23 in in IN cord-334550-xb0alubj 318 24 three three CD cord-334550-xb0alubj 318 25 southern southern JJ cord-334550-xb0alubj 318 26 Indian indian JJ cord-334550-xb0alubj 318 27 populations population NNS cord-334550-xb0alubj 318 28 : : : cord-334550-xb0alubj 319 1 comparison comparison NN cord-334550-xb0alubj 319 2 with with IN cord-334550-xb0alubj 319 3 world world NN cord-334550-xb0alubj 319 4 populations population NNS cord-334550-xb0alubj 319 5 revealed reveal VBD cord-334550-xb0alubj 319 6 a a DT cord-334550-xb0alubj 319 7 link link NN cord-334550-xb0alubj 319 8 between between IN cord-334550-xb0alubj 319 9 KIR KIR NNP cord-334550-xb0alubj 319 10 gene gene NN cord-334550-xb0alubj 319 11 content content NN cord-334550-xb0alubj 319 12 and and CC cord-334550-xb0alubj 319 13 pre pre JJ cord-334550-xb0alubj 319 14 - - JJ cord-334550-xb0alubj 319 15 historic historic JJ cord-334550-xb0alubj 319 16 human human JJ cord-334550-xb0alubj 319 17 migrations migration NNS cord-334550-xb0alubj 320 1 Differences difference NNS cord-334550-xb0alubj 320 2 in in IN cord-334550-xb0alubj 320 3 multiple multiple JJ cord-334550-xb0alubj 320 4 immune immune JJ cord-334550-xb0alubj 320 5 parameters parameter NNS cord-334550-xb0alubj 320 6 between between IN cord-334550-xb0alubj 320 7 Indian Indian NNP cord-334550-xb0alubj 320 8 and and CC cord-334550-xb0alubj 320 9 U.S. U.S. NNP cord-334550-xb0alubj 320 10 infants infant NNS cord-334550-xb0alubj 320 11 Comparative comparative JJ cord-334550-xb0alubj 320 12 analyses analysis NNS cord-334550-xb0alubj 320 13 of of IN cord-334550-xb0alubj 320 14 SAR SAR NNP cord-334550-xb0alubj 320 15 - - HYPH cord-334550-xb0alubj 320 16 CoV2 cov2 NN cord-334550-xb0alubj 320 17 genomes genome NNS cord-334550-xb0alubj 320 18 from from IN cord-334550-xb0alubj 320 19 different different JJ cord-334550-xb0alubj 320 20 geographical geographical JJ cord-334550-xb0alubj 320 21 locations location NNS cord-334550-xb0alubj 320 22 and and CC cord-334550-xb0alubj 320 23 other other JJ cord-334550-xb0alubj 320 24 coronavirus coronavirus NN cord-334550-xb0alubj 320 25 family family NN cord-334550-xb0alubj 320 26 genomes genome NNS cord-334550-xb0alubj 320 27 reveal reveal VBP cord-334550-xb0alubj 320 28 unique unique JJ cord-334550-xb0alubj 320 29 features feature NNS cord-334550-xb0alubj 320 30 potentially potentially RB cord-334550-xb0alubj 320 31 consequential consequential JJ cord-334550-xb0alubj 320 32 to to IN cord-334550-xb0alubj 320 33 hostvirus hostvirus JJ cord-334550-xb0alubj 320 34 interaction interaction NN cord-334550-xb0alubj 320 35 and and CC cord-334550-xb0alubj 320 36 pathogenesis pathogenesis NN cord-334550-xb0alubj 320 37 . . . cord-334550-xb0alubj 321 1 bioRxiv biorxiv DT cord-334550-xb0alubj 321 2 Indian indian JJ cord-334550-xb0alubj 321 3 food food NN cord-334550-xb0alubj 321 4 ingredients ingredient NNS cord-334550-xb0alubj 321 5 and and CC cord-334550-xb0alubj 321 6 cancer cancer NN cord-334550-xb0alubj 321 7 prevention prevention NN cord-334550-xb0alubj 321 8 -an -an : cord-334550-xb0alubj 321 9 experimental experimental JJ cord-334550-xb0alubj 321 10 evaluation evaluation NN cord-334550-xb0alubj 321 11 of of IN cord-334550-xb0alubj 321 12 anticarcinogenic anticarcinogenic JJ cord-334550-xb0alubj 321 13 effects effect NNS cord-334550-xb0alubj 321 14 of of IN cord-334550-xb0alubj 321 15 garlic garlic NN cord-334550-xb0alubj 321 16 in in IN cord-334550-xb0alubj 321 17 rat rat NN cord-334550-xb0alubj 321 18 colon colon NN cord-334550-xb0alubj 321 19 . . . cord-334550-xb0alubj 322 1 Asian asian JJ cord-334550-xb0alubj 322 2 Pac Pac NNP cord-334550-xb0alubj 322 3 BCG BCG NNP cord-334550-xb0alubj 322 4 modulation modulation NN cord-334550-xb0alubj 322 5 of of IN cord-334550-xb0alubj 322 6 delayed delayed JJ cord-334550-xb0alubj 322 7 type type NN cord-334550-xb0alubj 322 8 hypersensitivity hypersensitivity NN cord-334550-xb0alubj 322 9 , , , cord-334550-xb0alubj 322 10 humoral humoral JJ cord-334550-xb0alubj 322 11 response response NN cord-334550-xb0alubj 322 12 and and CC cord-334550-xb0alubj 322 13 acquired acquire VBN cord-334550-xb0alubj 322 14 resistance resistance NN cord-334550-xb0alubj 322 15 after after IN cord-334550-xb0alubj 322 16 rabies rabies NN cord-334550-xb0alubj 322 17 vaccination vaccination NN cord-334550-xb0alubj 323 1 The the DT cord-334550-xb0alubj 323 2 role role NN cord-334550-xb0alubj 323 3 of of IN cord-334550-xb0alubj 323 4 phylogenetic phylogenetic JJ cord-334550-xb0alubj 323 5 analysis analysis NN cord-334550-xb0alubj 323 6 in in IN cord-334550-xb0alubj 323 7 clarifying clarify VBG cord-334550-xb0alubj 323 8 the the DT cord-334550-xb0alubj 323 9 infection infection NN cord-334550-xb0alubj 323 10 source source NN cord-334550-xb0alubj 323 11 of of IN cord-334550-xb0alubj 323 12 a a DT cord-334550-xb0alubj 323 13 COVID-19 covid-19 JJ cord-334550-xb0alubj 323 14 patient patient NN cord-334550-xb0alubj 323 15 In in IN cord-334550-xb0alubj 323 16 vitro vitro FW cord-334550-xb0alubj 323 17 virucidal virucidal JJ cord-334550-xb0alubj 323 18 effects effect NNS cord-334550-xb0alubj 323 19 of of IN cord-334550-xb0alubj 323 20 Allium allium NN cord-334550-xb0alubj 323 21 sativum sativum NNP cord-334550-xb0alubj 323 22 ( ( -LRB- cord-334550-xb0alubj 323 23 garlic garlic NNP cord-334550-xb0alubj 323 24 ) ) -RRB- cord-334550-xb0alubj 323 25 extract extract NN cord-334550-xb0alubj 323 26 and and CC cord-334550-xb0alubj 323 27 compounds compound NNS cord-334550-xb0alubj 324 1 COVID-19 covid-19 VB cord-334550-xb0alubj 324 2 : : : cord-334550-xb0alubj 324 3 a a DT cord-334550-xb0alubj 324 4 new new JJ cord-334550-xb0alubj 324 5 challenge challenge NN cord-334550-xb0alubj 324 6 for for IN cord-334550-xb0alubj 324 7 human human JJ cord-334550-xb0alubj 324 8 beings being NNS cord-334550-xb0alubj 325 1 Traditional traditional JJ cord-334550-xb0alubj 325 2 chinese chinese JJ cord-334550-xb0alubj 325 3 medicine medicine NN cord-334550-xb0alubj 325 4 in in IN cord-334550-xb0alubj 325 5 the the DT cord-334550-xb0alubj 325 6 treatment treatment NN cord-334550-xb0alubj 325 7 of of IN cord-334550-xb0alubj 325 8 patients patient NNS cord-334550-xb0alubj 325 9 infected infect VBN cord-334550-xb0alubj 325 10 with with IN cord-334550-xb0alubj 325 11 2019-new 2019-new CD cord-334550-xb0alubj 325 12 coronavirus coronavirus NN cord-334550-xb0alubj 325 13 ( ( -LRB- cord-334550-xb0alubj 325 14 SARS SARS NNP cord-334550-xb0alubj 325 15 - - HYPH cord-334550-xb0alubj 325 16 CoV-2 CoV-2 NNP cord-334550-xb0alubj 325 17 ) ) -RRB- cord-334550-xb0alubj 325 18 : : : cord-334550-xb0alubj 325 19 a a DT cord-334550-xb0alubj 325 20 review review NN cord-334550-xb0alubj 325 21 and and CC cord-334550-xb0alubj 325 22 perspective perspective NN cord-334550-xb0alubj 326 1 No no DT cord-334550-xb0alubj 326 2 association association NN cord-334550-xb0alubj 326 3 of of IN cord-334550-xb0alubj 326 4 COVID-19 COVID-19 NNP cord-334550-xb0alubj 326 5 transmission transmission NN cord-334550-xb0alubj 326 6 with with IN cord-334550-xb0alubj 326 7 temperature temperature NN cord-334550-xb0alubj 326 8 or or CC cord-334550-xb0alubj 326 9 UV uv NN cord-334550-xb0alubj 326 10 radiation radiation NN cord-334550-xb0alubj 326 11 in in IN cord-334550-xb0alubj 326 12 Chinese chinese JJ cord-334550-xb0alubj 326 13 cities city NNS cord-334550-xb0alubj 327 1 Probable probable JJ cord-334550-xb0alubj 327 2 pangolin pangolin NN cord-334550-xb0alubj 327 3 origin origin NN cord-334550-xb0alubj 327 4 of of IN cord-334550-xb0alubj 327 5 SARS SARS NNP cord-334550-xb0alubj 327 6 - - HYPH cord-334550-xb0alubj 327 7 CoV-2 CoV-2 NNP cord-334550-xb0alubj 328 1 associated associate VBN cord-334550-xb0alubj 328 2 with with IN cord-334550-xb0alubj 328 3 the the DT cord-334550-xb0alubj 328 4 COVID-19 COVID-19 NNP cord-334550-xb0alubj 328 5 outbreak outbreak NN cord-334550-xb0alubj 328 6 SARS SARS NNP cord-334550-xb0alubj 328 7 - - HYPH cord-334550-xb0alubj 328 8 CoV-2 CoV-2 NNP cord-334550-xb0alubj 328 9 : : : cord-334550-xb0alubj 328 10 an an DT cord-334550-xb0alubj 328 11 emerging emerge VBG cord-334550-xb0alubj 328 12 coronavirus coronavirus NN cord-334550-xb0alubj 328 13 that that WDT cord-334550-xb0alubj 328 14 causes cause VBZ cord-334550-xb0alubj 328 15 a a DT cord-334550-xb0alubj 328 16 global global JJ cord-334550-xb0alubj 328 17 threat threat NN cord-334550-xb0alubj 328 18 The the DT cord-334550-xb0alubj 328 19 authors author NNS cord-334550-xb0alubj 328 20 declare declare VBP cord-334550-xb0alubj 328 21 that that IN cord-334550-xb0alubj 328 22 the the DT cord-334550-xb0alubj 328 23 research research NN cord-334550-xb0alubj 328 24 was be VBD cord-334550-xb0alubj 328 25 conducted conduct VBN cord-334550-xb0alubj 328 26 in in IN cord-334550-xb0alubj 328 27 the the DT cord-334550-xb0alubj 328 28 absence absence NN cord-334550-xb0alubj 328 29 of of IN cord-334550-xb0alubj 328 30 any any DT cord-334550-xb0alubj 328 31 commercial commercial JJ cord-334550-xb0alubj 328 32 or or CC cord-334550-xb0alubj 328 33 financial financial JJ cord-334550-xb0alubj 328 34 relationships relationship NNS cord-334550-xb0alubj 328 35 that that WDT cord-334550-xb0alubj 328 36 could could MD cord-334550-xb0alubj 328 37 be be VB cord-334550-xb0alubj 328 38 construed construe VBN cord-334550-xb0alubj 328 39 as as IN cord-334550-xb0alubj 328 40 a a DT cord-334550-xb0alubj 328 41 potential potential JJ cord-334550-xb0alubj 328 42 conflict conflict NN cord-334550-xb0alubj 328 43 of of IN cord-334550-xb0alubj 328 44 interest interest NN cord-334550-xb0alubj 328 45 . . . cord-334550-xb0alubj 329 1 Copyright copyright NN cord-334550-xb0alubj 329 2 © © NNP cord-334550-xb0alubj 329 3 2020 2020 CD cord-334550-xb0alubj 329 4 Samaddar Samaddar NNP cord-334550-xb0alubj 329 5 , , , cord-334550-xb0alubj 329 6 Gadepalli Gadepalli NNP cord-334550-xb0alubj 329 7 , , , cord-334550-xb0alubj 329 8 Nag Nag NNP cord-334550-xb0alubj 329 9 and and CC cord-334550-xb0alubj 329 10 Misra Misra NNP cord-334550-xb0alubj 329 11 . . . cord-334550-xb0alubj 330 1 This this DT cord-334550-xb0alubj 330 2 is be VBZ cord-334550-xb0alubj 330 3 an an DT cord-334550-xb0alubj 330 4 open open JJ cord-334550-xb0alubj 330 5 - - HYPH cord-334550-xb0alubj 330 6 access access NN cord-334550-xb0alubj 330 7 article article NN cord-334550-xb0alubj 330 8 distributed distribute VBN cord-334550-xb0alubj 330 9 under under IN cord-334550-xb0alubj 330 10 the the DT cord-334550-xb0alubj 330 11 terms term NNS cord-334550-xb0alubj 330 12 of of IN cord-334550-xb0alubj 330 13 the the DT cord-334550-xb0alubj 330 14 Creative Creative NNP cord-334550-xb0alubj 330 15 Commons Commons NNP cord-334550-xb0alubj 330 16 Attribution Attribution NNP cord-334550-xb0alubj 330 17 License License NNP cord-334550-xb0alubj 330 18 ( ( -LRB- cord-334550-xb0alubj 330 19 CC CC NNP cord-334550-xb0alubj 330 20 BY BY NNP cord-334550-xb0alubj 330 21 ) ) -RRB- cord-334550-xb0alubj 330 22 . . . cord-334550-xb0alubj 331 1 The the DT cord-334550-xb0alubj 331 2 use use NN cord-334550-xb0alubj 331 3 , , , cord-334550-xb0alubj 331 4 distribution distribution NN cord-334550-xb0alubj 331 5 or or CC cord-334550-xb0alubj 331 6 reproduction reproduction NN cord-334550-xb0alubj 331 7 in in IN cord-334550-xb0alubj 331 8 other other JJ cord-334550-xb0alubj 331 9 forums forum NNS cord-334550-xb0alubj 331 10 is be VBZ cord-334550-xb0alubj 331 11 permitted permit VBN cord-334550-xb0alubj 331 12 , , , cord-334550-xb0alubj 331 13 provided provide VBD cord-334550-xb0alubj 331 14 the the DT cord-334550-xb0alubj 331 15 original original JJ cord-334550-xb0alubj 331 16 author(s author(s NNP cord-334550-xb0alubj 331 17 ) ) -RRB- cord-334550-xb0alubj 331 18 and and CC cord-334550-xb0alubj 331 19 the the DT cord-334550-xb0alubj 331 20 copyright copyright NN cord-334550-xb0alubj 331 21 owner(s owner(s NNP cord-334550-xb0alubj 331 22 ) ) -RRB- cord-334550-xb0alubj 331 23 are be VBP cord-334550-xb0alubj 331 24 credited credit VBN cord-334550-xb0alubj 331 25 and and CC cord-334550-xb0alubj 331 26 that that IN cord-334550-xb0alubj 331 27 the the DT cord-334550-xb0alubj 331 28 original original JJ cord-334550-xb0alubj 331 29 publication publication NN cord-334550-xb0alubj 331 30 in in IN cord-334550-xb0alubj 331 31 this this DT cord-334550-xb0alubj 331 32 journal journal NN cord-334550-xb0alubj 331 33 is be VBZ cord-334550-xb0alubj 331 34 cited cite VBN cord-334550-xb0alubj 331 35 , , , cord-334550-xb0alubj 331 36 in in IN cord-334550-xb0alubj 331 37 accordance accordance NN cord-334550-xb0alubj 331 38 with with IN cord-334550-xb0alubj 331 39 accepted accepted JJ cord-334550-xb0alubj 331 40 academic academic JJ cord-334550-xb0alubj 331 41 practice practice NN cord-334550-xb0alubj 331 42 . . . cord-334550-xb0alubj 332 1 No no DT cord-334550-xb0alubj 332 2 use use NN cord-334550-xb0alubj 332 3 , , , cord-334550-xb0alubj 332 4 distribution distribution NN cord-334550-xb0alubj 332 5 or or CC cord-334550-xb0alubj 332 6 reproduction reproduction NN cord-334550-xb0alubj 332 7 is be VBZ cord-334550-xb0alubj 332 8 permitted permit VBN cord-334550-xb0alubj 332 9 which which WDT cord-334550-xb0alubj 332 10 does do VBZ cord-334550-xb0alubj 332 11 not not RB cord-334550-xb0alubj 332 12 comply comply VB cord-334550-xb0alubj 332 13 with with IN cord-334550-xb0alubj 332 14 these these DT cord-334550-xb0alubj 332 15 terms term NNS cord-334550-xb0alubj 332 16 . . .