id sid tid token lemma pos cord-333696-3ci9re9a 1 1 key key JJ cord-333696-3ci9re9a 1 2 : : : cord-333696-3ci9re9a 1 3 cord-333696 cord-333696 NNP cord-333696-3ci9re9a 1 4 - - HYPH cord-333696-3ci9re9a 1 5 3ci9re9a 3ci9re9a CD cord-333696-3ci9re9a 1 6 authors author NNS cord-333696-3ci9re9a 1 7 : : : cord-333696-3ci9re9a 1 8 Alomari Alomari NNP cord-333696-3ci9re9a 1 9 , , , cord-333696-3ci9re9a 1 10 Safwan Safwan NNP cord-333696-3ci9re9a 1 11 O. O. NNP cord-333696-3ci9re9a 1 12 ; ; : cord-333696-3ci9re9a 1 13 Abou Abou NNP cord-333696-3ci9re9a 1 14 - - HYPH cord-333696-3ci9re9a 1 15 Mrad Mrad NNP cord-333696-3ci9re9a 1 16 , , , cord-333696-3ci9re9a 1 17 Zaki Zaki NNP cord-333696-3ci9re9a 1 18 ; ; : cord-333696-3ci9re9a 1 19 Bydon Bydon NNP cord-333696-3ci9re9a 1 20 , , , cord-333696-3ci9re9a 1 21 Ali Ali NNP cord-333696-3ci9re9a 1 22 title title NN cord-333696-3ci9re9a 1 23 : : : cord-333696-3ci9re9a 1 24 COVID-19 covid-19 VB cord-333696-3ci9re9a 1 25 and and CC cord-333696-3ci9re9a 1 26 the the DT cord-333696-3ci9re9a 1 27 Central Central NNP cord-333696-3ci9re9a 1 28 Nervous Nervous NNP cord-333696-3ci9re9a 1 29 System System NNP cord-333696-3ci9re9a 1 30 date date NN cord-333696-3ci9re9a 1 31 : : : cord-333696-3ci9re9a 1 32 2020 2020 CD cord-333696-3ci9re9a 1 33 - - HYPH cord-333696-3ci9re9a 1 34 08 08 CD cord-333696-3ci9re9a 1 35 - - HYPH cord-333696-3ci9re9a 1 36 04 04 CD cord-333696-3ci9re9a 1 37 journal journal NN cord-333696-3ci9re9a 1 38 : : : cord-333696-3ci9re9a 1 39 Clin Clin NNP cord-333696-3ci9re9a 1 40 Neurol Neurol NNP cord-333696-3ci9re9a 2 1 Neurosurg Neurosurg NNP cord-333696-3ci9re9a 2 2 DOI DOI NNP cord-333696-3ci9re9a 2 3 : : : cord-333696-3ci9re9a 2 4 10.1016 10.1016 CD cord-333696-3ci9re9a 2 5 / / SYM cord-333696-3ci9re9a 2 6 j.clineuro.2020.106116 j.clineuro.2020.106116 NN cord-333696-3ci9re9a 2 7 sha sha NNP cord-333696-3ci9re9a 2 8 : : : cord-333696-3ci9re9a 2 9 a97e7c39c5f02ba8ed1eb941605449d6fe9106af a97e7c39c5f02ba8ed1eb941605449d6fe9106af UH cord-333696-3ci9re9a 2 10 doc_id doc_id NNP cord-333696-3ci9re9a 2 11 : : : cord-333696-3ci9re9a 2 12 333696 333696 CD cord-333696-3ci9re9a 2 13 cord_uid cord_uid NN cord-333696-3ci9re9a 2 14 : : : cord-333696-3ci9re9a 3 1 3ci9re9a 3ci9re9a CD cord-333696-3ci9re9a 3 2 • • NNP cord-333696-3ci9re9a 4 1 As as IN cord-333696-3ci9re9a 4 2 the the DT cord-333696-3ci9re9a 4 3 number number NN cord-333696-3ci9re9a 4 4 of of IN cord-333696-3ci9re9a 4 5 patients patient NNS cord-333696-3ci9re9a 4 6 with with IN cord-333696-3ci9re9a 4 7 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 4 8 is be VBZ cord-333696-3ci9re9a 4 9 increasing increase VBG cord-333696-3ci9re9a 4 10 worldwide worldwide RB cord-333696-3ci9re9a 4 11 , , , cord-333696-3ci9re9a 4 12 it -PRON- PRP cord-333696-3ci9re9a 4 13 is be VBZ cord-333696-3ci9re9a 4 14 necessary necessary JJ cord-333696-3ci9re9a 4 15 to to TO cord-333696-3ci9re9a 4 16 stress stress VB cord-333696-3ci9re9a 4 17 on on IN cord-333696-3ci9re9a 4 18 the the DT cord-333696-3ci9re9a 4 19 importance importance NN cord-333696-3ci9re9a 4 20 of of IN cord-333696-3ci9re9a 4 21 the the DT cord-333696-3ci9re9a 4 22 atypical atypical JJ cord-333696-3ci9re9a 4 23 clinical clinical JJ cord-333696-3ci9re9a 4 24 presentations presentation NNS cord-333696-3ci9re9a 4 25 ( ( -LRB- cord-333696-3ci9re9a 4 26 including include VBG cord-333696-3ci9re9a 4 27 those those DT cord-333696-3ci9re9a 4 28 related relate VBN cord-333696-3ci9re9a 4 29 to to IN cord-333696-3ci9re9a 4 30 the the DT cord-333696-3ci9re9a 4 31 nervous nervous JJ cord-333696-3ci9re9a 4 32 system system NN cord-333696-3ci9re9a 4 33 ) ) -RRB- cord-333696-3ci9re9a 4 34 of of IN cord-333696-3ci9re9a 4 35 COVID-19 covid-19 JJ cord-333696-3ci9re9a 4 36 infection infection NN cord-333696-3ci9re9a 4 37 , , , cord-333696-3ci9re9a 4 38 since since IN cord-333696-3ci9re9a 4 39 they -PRON- PRP cord-333696-3ci9re9a 4 40 might may MD cord-333696-3ci9re9a 4 41 be be VB cord-333696-3ci9re9a 4 42 the the DT cord-333696-3ci9re9a 4 43 initial initial JJ cord-333696-3ci9re9a 4 44 manifestations manifestation NNS cord-333696-3ci9re9a 4 45 . . . cord-333696-3ci9re9a 5 1 • • NNP cord-333696-3ci9re9a 6 1 Literature literature NN cord-333696-3ci9re9a 6 2 on on IN cord-333696-3ci9re9a 6 3 this this DT cord-333696-3ci9re9a 6 4 regard regard NN cord-333696-3ci9re9a 6 5 should should MD cord-333696-3ci9re9a 6 6 be be VB cord-333696-3ci9re9a 6 7 sent send VBN cord-333696-3ci9re9a 6 8 by by IN cord-333696-3ci9re9a 6 9 the the DT cord-333696-3ci9re9a 6 10 international international JJ cord-333696-3ci9re9a 6 11 and and CC cord-333696-3ci9re9a 6 12 local local JJ cord-333696-3ci9re9a 6 13 health health NN cord-333696-3ci9re9a 6 14 committees committee NNS cord-333696-3ci9re9a 6 15 to to IN cord-333696-3ci9re9a 6 16 all all DT cord-333696-3ci9re9a 6 17 health health NN cord-333696-3ci9re9a 6 18 - - HYPH cord-333696-3ci9re9a 6 19 care care NN cord-333696-3ci9re9a 6 20 providers provider NNS cord-333696-3ci9re9a 6 21 during during IN cord-333696-3ci9re9a 6 22 this this DT cord-333696-3ci9re9a 6 23 COVID covid NN cord-333696-3ci9re9a 6 24 -19 -19 NN cord-333696-3ci9re9a 6 25 pandemic pandemic NN cord-333696-3ci9re9a 6 26 , , , cord-333696-3ci9re9a 6 27 to to TO cord-333696-3ci9re9a 6 28 make make VB cord-333696-3ci9re9a 6 29 sure sure JJ cord-333696-3ci9re9a 6 30 that that IN cord-333696-3ci9re9a 6 31 all all DT cord-333696-3ci9re9a 6 32 providers provider NNS cord-333696-3ci9re9a 6 33 are be VBP cord-333696-3ci9re9a 6 34 well well RB cord-333696-3ci9re9a 6 35 informed informed JJ cord-333696-3ci9re9a 6 36 and and CC cord-333696-3ci9re9a 6 37 aware aware JJ cord-333696-3ci9re9a 6 38 of of IN cord-333696-3ci9re9a 6 39 these these DT cord-333696-3ci9re9a 6 40 cases case NNS cord-333696-3ci9re9a 6 41 . . . cord-333696-3ci9re9a 7 1 • • NNP cord-333696-3ci9re9a 8 1 More More JJR cord-333696-3ci9re9a 8 2 studies study NNS cord-333696-3ci9re9a 8 3 are be VBP cord-333696-3ci9re9a 8 4 deeply deeply RB cord-333696-3ci9re9a 8 5 needed need VBN cord-333696-3ci9re9a 8 6 to to TO cord-333696-3ci9re9a 8 7 enable enable VB cord-333696-3ci9re9a 8 8 the the DT cord-333696-3ci9re9a 8 9 concerned concerned JJ cord-333696-3ci9re9a 8 10 committees committee NNS cord-333696-3ci9re9a 8 11 to to TO cord-333696-3ci9re9a 8 12 make make VB cord-333696-3ci9re9a 8 13 evidence evidence NN cord-333696-3ci9re9a 8 14 - - HYPH cord-333696-3ci9re9a 8 15 based base VBN cord-333696-3ci9re9a 8 16 guidelines guideline NNS cord-333696-3ci9re9a 8 17 for for IN cord-333696-3ci9re9a 8 18 prevention prevention NN cord-333696-3ci9re9a 8 19 , , , cord-333696-3ci9re9a 8 20 early early JJ cord-333696-3ci9re9a 8 21 detection detection NN cord-333696-3ci9re9a 8 22 and and CC cord-333696-3ci9re9a 8 23 appropriate appropriate JJ cord-333696-3ci9re9a 8 24 management management NN cord-333696-3ci9re9a 8 25 of of IN cord-333696-3ci9re9a 8 26 these these DT cord-333696-3ci9re9a 8 27 cases case NNS cord-333696-3ci9re9a 8 28 . . . cord-333696-3ci9re9a 9 1 At at IN cord-333696-3ci9re9a 9 2 the the DT cord-333696-3ci9re9a 9 3 beginning beginning NN cord-333696-3ci9re9a 9 4 of of IN cord-333696-3ci9re9a 9 5 December December NNP cord-333696-3ci9re9a 9 6 2019 2019 CD cord-333696-3ci9re9a 9 7 , , , cord-333696-3ci9re9a 9 8 Wuhan Wuhan NNP cord-333696-3ci9re9a 9 9 , , , cord-333696-3ci9re9a 9 10 the the DT cord-333696-3ci9re9a 9 11 capital capital NN cord-333696-3ci9re9a 9 12 of of IN cord-333696-3ci9re9a 9 13 Hubei Hubei NNP cord-333696-3ci9re9a 9 14 Province Province NNP cord-333696-3ci9re9a 9 15 and and CC cord-333696-3ci9re9a 9 16 a a DT cord-333696-3ci9re9a 9 17 large large JJ cord-333696-3ci9re9a 9 18 city city NN cord-333696-3ci9re9a 9 19 of of IN cord-333696-3ci9re9a 9 20 approximately approximately RB cord-333696-3ci9re9a 9 21 11 11 CD cord-333696-3ci9re9a 9 22 million million CD cord-333696-3ci9re9a 9 23 persons person NNS cord-333696-3ci9re9a 9 24 located locate VBN cord-333696-3ci9re9a 9 25 in in IN cord-333696-3ci9re9a 9 26 the the DT cord-333696-3ci9re9a 9 27 central central JJ cord-333696-3ci9re9a 9 28 region region NN cord-333696-3ci9re9a 9 29 of of IN cord-333696-3ci9re9a 9 30 the the DT cord-333696-3ci9re9a 9 31 People People NNPS cord-333696-3ci9re9a 9 32 's 's POS cord-333696-3ci9re9a 9 33 Republic Republic NNP cord-333696-3ci9re9a 9 34 of of IN cord-333696-3ci9re9a 9 35 China China NNP cord-333696-3ci9re9a 9 36 , , , cord-333696-3ci9re9a 9 37 witnessed witness VBD cord-333696-3ci9re9a 9 38 an an DT cord-333696-3ci9re9a 9 39 outbreak outbreak NN cord-333696-3ci9re9a 9 40 of of IN cord-333696-3ci9re9a 9 41 a a DT cord-333696-3ci9re9a 9 42 cluster cluster NN cord-333696-3ci9re9a 9 43 of of IN cord-333696-3ci9re9a 9 44 persons person NNS cord-333696-3ci9re9a 9 45 with with IN cord-333696-3ci9re9a 9 46 viral viral JJ cord-333696-3ci9re9a 9 47 pneumonia pneumonia NN cord-333696-3ci9re9a 9 48 of of IN cord-333696-3ci9re9a 9 49 unknown unknown JJ cord-333696-3ci9re9a 9 50 agent agent NN cord-333696-3ci9re9a 9 51 . . . cord-333696-3ci9re9a 10 1 On on IN cord-333696-3ci9re9a 10 2 7 7 CD cord-333696-3ci9re9a 10 3 January January NNP cord-333696-3ci9re9a 10 4 2020 2020 CD cord-333696-3ci9re9a 10 5 , , , cord-333696-3ci9re9a 10 6 a a DT cord-333696-3ci9re9a 10 7 group group NN cord-333696-3ci9re9a 10 8 of of IN cord-333696-3ci9re9a 10 9 Chinese chinese JJ cord-333696-3ci9re9a 10 10 scientists scientist NNS cord-333696-3ci9re9a 10 11 succeeded succeed VBD cord-333696-3ci9re9a 10 12 to to TO cord-333696-3ci9re9a 10 13 identify identify VB cord-333696-3ci9re9a 10 14 the the DT cord-333696-3ci9re9a 10 15 etiological etiological JJ cord-333696-3ci9re9a 10 16 agent agent NN cord-333696-3ci9re9a 10 17 of of IN cord-333696-3ci9re9a 10 18 the the DT cord-333696-3ci9re9a 10 19 epidemic epidemic NN cord-333696-3ci9re9a 10 20 as as IN cord-333696-3ci9re9a 10 21 a a DT cord-333696-3ci9re9a 10 22 previously previously RB cord-333696-3ci9re9a 10 23 unknown unknown JJ cord-333696-3ci9re9a 10 24 coronavirus coronavirus NN cord-333696-3ci9re9a 10 25 , , , cord-333696-3ci9re9a 10 26 and and CC cord-333696-3ci9re9a 10 27 they -PRON- PRP cord-333696-3ci9re9a 10 28 named name VBD cord-333696-3ci9re9a 10 29 it -PRON- PRP cord-333696-3ci9re9a 10 30 by by IN cord-333696-3ci9re9a 10 31 2019-nCoV 2019-ncov CD cord-333696-3ci9re9a 10 32 ( ( -LRB- cord-333696-3ci9re9a 10 33 for for IN cord-333696-3ci9re9a 10 34 2019 2019 CD cord-333696-3ci9re9a 10 35 novel novel JJ cord-333696-3ci9re9a 10 36 coronavirus coronavirus NN cord-333696-3ci9re9a 10 37 ) ) -RRB- cord-333696-3ci9re9a 10 38 [ [ -LRB- cord-333696-3ci9re9a 10 39 1 1 CD cord-333696-3ci9re9a 10 40 , , , cord-333696-3ci9re9a 10 41 2 2 CD cord-333696-3ci9re9a 10 42 ] ] -RRB- cord-333696-3ci9re9a 10 43 . . . cord-333696-3ci9re9a 11 1 At at IN cord-333696-3ci9re9a 11 2 the the DT cord-333696-3ci9re9a 11 3 beginning beginning NN cord-333696-3ci9re9a 11 4 of of IN cord-333696-3ci9re9a 11 5 January January NNP cord-333696-3ci9re9a 11 6 2020 2020 CD cord-333696-3ci9re9a 11 7 , , , cord-333696-3ci9re9a 11 8 the the DT cord-333696-3ci9re9a 11 9 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 11 10 virus virus NN cord-333696-3ci9re9a 11 11 has have VBZ cord-333696-3ci9re9a 11 12 spread spread VBN cord-333696-3ci9re9a 11 13 to to IN cord-333696-3ci9re9a 11 14 other other JJ cord-333696-3ci9re9a 11 15 countries country NNS cord-333696-3ci9re9a 11 16 including include VBG cord-333696-3ci9re9a 11 17 Japan Japan NNP cord-333696-3ci9re9a 11 18 , , , cord-333696-3ci9re9a 11 19 Korea Korea NNP cord-333696-3ci9re9a 11 20 , , , cord-333696-3ci9re9a 11 21 Thailand Thailand NNP cord-333696-3ci9re9a 11 22 , , , cord-333696-3ci9re9a 11 23 Iran Iran NNP cord-333696-3ci9re9a 11 24 , , , cord-333696-3ci9re9a 11 25 and and CC cord-333696-3ci9re9a 11 26 the the DT cord-333696-3ci9re9a 11 27 United United NNP cord-333696-3ci9re9a 11 28 States States NNP cord-333696-3ci9re9a 11 29 [ [ -LRB- cord-333696-3ci9re9a 11 30 3 3 CD cord-333696-3ci9re9a 11 31 ] ] -RRB- cord-333696-3ci9re9a 11 32 . . . cord-333696-3ci9re9a 12 1 The the DT cord-333696-3ci9re9a 12 2 novel novel JJ cord-333696-3ci9re9a 12 3 coronavirus coronavirus NN cord-333696-3ci9re9a 12 4 disease disease NN cord-333696-3ci9re9a 12 5 received receive VBD cord-333696-3ci9re9a 12 6 an an DT cord-333696-3ci9re9a 12 7 official official JJ cord-333696-3ci9re9a 12 8 name name NN cord-333696-3ci9re9a 12 9 by by IN cord-333696-3ci9re9a 12 10 the the DT cord-333696-3ci9re9a 12 11 World World NNP cord-333696-3ci9re9a 12 12 Health Health NNP cord-333696-3ci9re9a 12 13 Organization Organization NNP cord-333696-3ci9re9a 12 14 ( ( -LRB- cord-333696-3ci9re9a 12 15 WHO who WP cord-333696-3ci9re9a 12 16 ) ) -RRB- cord-333696-3ci9re9a 12 17 as as IN cord-333696-3ci9re9a 12 18 Coronavirus Coronavirus NNP cord-333696-3ci9re9a 12 19 , , , cord-333696-3ci9re9a 12 20 on on IN cord-333696-3ci9re9a 12 21 February February NNP cord-333696-3ci9re9a 12 22 11 11 CD cord-333696-3ci9re9a 12 23 , , , cord-333696-3ci9re9a 12 24 2020 2020 CD cord-333696-3ci9re9a 12 25 [ [ -LRB- cord-333696-3ci9re9a 12 26 4 4 CD cord-333696-3ci9re9a 12 27 ] ] -RRB- cord-333696-3ci9re9a 12 28 . . . cord-333696-3ci9re9a 13 1 Later later RBR cord-333696-3ci9re9a 13 2 , , , cord-333696-3ci9re9a 13 3 the the DT cord-333696-3ci9re9a 13 4 International International NNP cord-333696-3ci9re9a 13 5 Committee Committee NNP cord-333696-3ci9re9a 13 6 on on IN cord-333696-3ci9re9a 13 7 Taxonomy Taxonomy NNP cord-333696-3ci9re9a 13 8 of of IN cord-333696-3ci9re9a 13 9 Viruses Viruses NNPS cord-333696-3ci9re9a 13 10 has have VBZ cord-333696-3ci9re9a 13 11 suggested suggest VBN cord-333696-3ci9re9a 13 12 SARS SARS NNP cord-333696-3ci9re9a 13 13 - - HYPH cord-333696-3ci9re9a 13 14 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 13 15 as as IN cord-333696-3ci9re9a 13 16 the the DT cord-333696-3ci9re9a 13 17 name name NN cord-333696-3ci9re9a 13 18 of of IN cord-333696-3ci9re9a 13 19 the the DT cord-333696-3ci9re9a 13 20 virus virus NN cord-333696-3ci9re9a 13 21 that that WDT cord-333696-3ci9re9a 13 22 causes cause VBZ cord-333696-3ci9re9a 13 23 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 13 24 [ [ -LRB- cord-333696-3ci9re9a 13 25 5 5 CD cord-333696-3ci9re9a 13 26 ] ] -RRB- cord-333696-3ci9re9a 13 27 . . . cord-333696-3ci9re9a 14 1 The the DT cord-333696-3ci9re9a 14 2 World World NNP cord-333696-3ci9re9a 14 3 Health Health NNP cord-333696-3ci9re9a 14 4 Organization Organization NNP cord-333696-3ci9re9a 14 5 declared declare VBD cord-333696-3ci9re9a 14 6 the the DT cord-333696-3ci9re9a 14 7 virus virus NN cord-333696-3ci9re9a 14 8 outbreak outbreak NN cord-333696-3ci9re9a 14 9 a a DT cord-333696-3ci9re9a 14 10 pandemic pandemic NN cord-333696-3ci9re9a 14 11 on on IN cord-333696-3ci9re9a 14 12 March March NNP cord-333696-3ci9re9a 14 13 11 11 CD cord-333696-3ci9re9a 14 14 , , , cord-333696-3ci9re9a 14 15 2020 2020 CD cord-333696-3ci9re9a 14 16 [ [ -LRB- cord-333696-3ci9re9a 14 17 6 6 CD cord-333696-3ci9re9a 14 18 ] ] -RRB- cord-333696-3ci9re9a 14 19 . . . cord-333696-3ci9re9a 15 1 The the DT cord-333696-3ci9re9a 15 2 primary primary JJ cord-333696-3ci9re9a 15 3 symptoms symptom NNS cord-333696-3ci9re9a 15 4 of of IN cord-333696-3ci9re9a 15 5 COVID-19 covid-19 DT cord-333696-3ci9re9a 15 6 include include VBP cord-333696-3ci9re9a 15 7 fever fever NN cord-333696-3ci9re9a 15 8 , , , cord-333696-3ci9re9a 15 9 dry dry JJ cord-333696-3ci9re9a 15 10 cough cough NN cord-333696-3ci9re9a 15 11 , , , cord-333696-3ci9re9a 15 12 and and CC cord-333696-3ci9re9a 15 13 fatigue fatigue NN cord-333696-3ci9re9a 15 14 [ [ -LRB- cord-333696-3ci9re9a 15 15 7 7 CD cord-333696-3ci9re9a 15 16 ] ] -RRB- cord-333696-3ci9re9a 15 17 . . . cord-333696-3ci9re9a 16 1 However however RB cord-333696-3ci9re9a 16 2 , , , cord-333696-3ci9re9a 16 3 some some DT cord-333696-3ci9re9a 16 4 patients patient NNS cord-333696-3ci9re9a 16 5 diagnosed diagnose VBN cord-333696-3ci9re9a 16 6 with with IN cord-333696-3ci9re9a 16 7 COVID- covid- NN cord-333696-3ci9re9a 16 8 19 19 CD cord-333696-3ci9re9a 16 9 have have VBP cord-333696-3ci9re9a 16 10 not not RB cord-333696-3ci9re9a 16 11 shown show VBN cord-333696-3ci9re9a 16 12 these these DT cord-333696-3ci9re9a 16 13 typical typical JJ cord-333696-3ci9re9a 16 14 symptoms symptom NNS cord-333696-3ci9re9a 16 15 , , , cord-333696-3ci9re9a 16 16 at at IN cord-333696-3ci9re9a 16 17 the the DT cord-333696-3ci9re9a 16 18 time time NN cord-333696-3ci9re9a 16 19 of of IN cord-333696-3ci9re9a 16 20 diagnosis diagnosis NN cord-333696-3ci9re9a 16 21 ; ; : cord-333696-3ci9re9a 16 22 instead instead RB cord-333696-3ci9re9a 16 23 , , , cord-333696-3ci9re9a 16 24 they -PRON- PRP cord-333696-3ci9re9a 16 25 have have VBP cord-333696-3ci9re9a 16 26 exhibited exhibit VBN cord-333696-3ci9re9a 16 27 only only JJ cord-333696-3ci9re9a 16 28 neurological neurological JJ cord-333696-3ci9re9a 16 29 symptoms symptom NNS cord-333696-3ci9re9a 16 30 as as IN cord-333696-3ci9re9a 16 31 the the DT cord-333696-3ci9re9a 16 32 initial initial JJ cord-333696-3ci9re9a 16 33 symptoms symptom NNS cord-333696-3ci9re9a 16 34 , , , cord-333696-3ci9re9a 16 35 such such JJ cord-333696-3ci9re9a 16 36 as as IN cord-333696-3ci9re9a 16 37 the the DT cord-333696-3ci9re9a 16 38 following follow VBG cord-333696-3ci9re9a 16 39 : : : cord-333696-3ci9re9a 16 40 non non JJ cord-333696-3ci9re9a 16 41 - - JJ cord-333696-3ci9re9a 16 42 specific specific JJ cord-333696-3ci9re9a 16 43 manifestations manifestation NNS cord-333696-3ci9re9a 16 44 including include VBG cord-333696-3ci9re9a 16 45 headache headache NN cord-333696-3ci9re9a 16 46 , , , cord-333696-3ci9re9a 16 47 malaise malaise NN cord-333696-3ci9re9a 16 48 and and CC cord-333696-3ci9re9a 16 49 unstable unstable JJ cord-333696-3ci9re9a 16 50 walking walking NN cord-333696-3ci9re9a 16 51 , , , cord-333696-3ci9re9a 16 52 cerebral cerebral JJ cord-333696-3ci9re9a 16 53 hemorrhage hemorrhage NN cord-333696-3ci9re9a 16 54 , , , cord-333696-3ci9re9a 16 55 cerebral cerebral JJ cord-333696-3ci9re9a 16 56 infarction infarction NN cord-333696-3ci9re9a 16 57 ; ; : cord-333696-3ci9re9a 16 58 as as RB cord-333696-3ci9re9a 16 59 well well RB cord-333696-3ci9re9a 16 60 as as IN cord-333696-3ci9re9a 16 61 other other JJ cord-333696-3ci9re9a 16 62 neurological neurological JJ cord-333696-3ci9re9a 16 63 diseases disease NNS cord-333696-3ci9re9a 16 64 [ [ -LRB- cord-333696-3ci9re9a 16 65 8 8 CD cord-333696-3ci9re9a 16 66 ] ] -RRB- cord-333696-3ci9re9a 16 67 . . . cord-333696-3ci9re9a 17 1 Until until IN cord-333696-3ci9re9a 17 2 now now RB cord-333696-3ci9re9a 17 3 , , , cord-333696-3ci9re9a 17 4 we -PRON- PRP cord-333696-3ci9re9a 17 5 have have VBP cord-333696-3ci9re9a 17 6 scarce scarce JJ cord-333696-3ci9re9a 17 7 literature literature NN cord-333696-3ci9re9a 17 8 on on IN cord-333696-3ci9re9a 17 9 COVID-19 covid-19 JJ cord-333696-3ci9re9a 17 10 aspects aspect NNS cord-333696-3ci9re9a 17 11 related relate VBN cord-333696-3ci9re9a 17 12 to to IN cord-333696-3ci9re9a 17 13 the the DT cord-333696-3ci9re9a 17 14 nervous nervous JJ cord-333696-3ci9re9a 17 15 system system NN cord-333696-3ci9re9a 17 16 . . . cord-333696-3ci9re9a 18 1 In in IN cord-333696-3ci9re9a 18 2 this this DT cord-333696-3ci9re9a 18 3 article article NN cord-333696-3ci9re9a 18 4 , , , cord-333696-3ci9re9a 18 5 the the DT cord-333696-3ci9re9a 18 6 authors author NNS cord-333696-3ci9re9a 18 7 discuss discuss VBP cord-333696-3ci9re9a 18 8 the the DT cord-333696-3ci9re9a 18 9 neurological neurological JJ cord-333696-3ci9re9a 18 10 aspects aspect NNS cord-333696-3ci9re9a 18 11 of of IN cord-333696-3ci9re9a 18 12 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 18 13 and and CC cord-333696-3ci9re9a 18 14 provide provide VB cord-333696-3ci9re9a 18 15 a a DT cord-333696-3ci9re9a 18 16 concise concise JJ cord-333696-3ci9re9a 18 17 review review NN cord-333696-3ci9re9a 18 18 of of IN cord-333696-3ci9re9a 18 19 the the DT cord-333696-3ci9re9a 18 20 reported report VBN cord-333696-3ci9re9a 18 21 literature literature NN cord-333696-3ci9re9a 18 22 on on IN cord-333696-3ci9re9a 18 23 this this DT cord-333696-3ci9re9a 18 24 field field NN cord-333696-3ci9re9a 18 25 . . . cord-333696-3ci9re9a 19 1 For for IN cord-333696-3ci9re9a 19 2 a a DT cord-333696-3ci9re9a 19 3 given give VBN cord-333696-3ci9re9a 19 4 virus virus NN cord-333696-3ci9re9a 19 5 , , , cord-333696-3ci9re9a 19 6 the the DT cord-333696-3ci9re9a 19 7 ability ability NN cord-333696-3ci9re9a 19 8 to to TO cord-333696-3ci9re9a 19 9 infect infect VB cord-333696-3ci9re9a 19 10 certain certain JJ cord-333696-3ci9re9a 19 11 cells cell NNS cord-333696-3ci9re9a 19 12 , , , cord-333696-3ci9re9a 19 13 tissues tissue NNS cord-333696-3ci9re9a 19 14 , , , cord-333696-3ci9re9a 19 15 or or CC cord-333696-3ci9re9a 19 16 even even RB cord-333696-3ci9re9a 19 17 species specie NNS cord-333696-3ci9re9a 19 18 while while IN cord-333696-3ci9re9a 19 19 not not RB cord-333696-3ci9re9a 19 20 affecting affect VBG cord-333696-3ci9re9a 19 21 others other NNS cord-333696-3ci9re9a 19 22 is be VBZ cord-333696-3ci9re9a 19 23 referred refer VBN cord-333696-3ci9re9a 19 24 to to IN cord-333696-3ci9re9a 19 25 as as IN cord-333696-3ci9re9a 19 26 viral viral JJ cord-333696-3ci9re9a 19 27 tropism tropism NN cord-333696-3ci9re9a 19 28 [ [ -LRB- cord-333696-3ci9re9a 19 29 9 9 CD cord-333696-3ci9re9a 19 30 ] ] -RRB- cord-333696-3ci9re9a 19 31 . . . cord-333696-3ci9re9a 20 1 This this DT cord-333696-3ci9re9a 20 2 viral viral JJ cord-333696-3ci9re9a 20 3 tropism tropism NN cord-333696-3ci9re9a 20 4 , , , cord-333696-3ci9re9a 20 5 allowing allow VBG cord-333696-3ci9re9a 20 6 a a DT cord-333696-3ci9re9a 20 7 virus virus NN cord-333696-3ci9re9a 20 8 to to TO cord-333696-3ci9re9a 20 9 replicate replicate VB cord-333696-3ci9re9a 20 10 in in RP cord-333696-3ci9re9a 20 11 and and CC cord-333696-3ci9re9a 20 12 affect affect VB cord-333696-3ci9re9a 20 13 certain certain JJ cord-333696-3ci9re9a 20 14 body body NN cord-333696-3ci9re9a 20 15 tissues tissue NNS cord-333696-3ci9re9a 20 16 , , , cord-333696-3ci9re9a 20 17 would would MD cord-333696-3ci9re9a 20 18 then then RB cord-333696-3ci9re9a 20 19 lead lead VB cord-333696-3ci9re9a 20 20 to to IN cord-333696-3ci9re9a 20 21 the the DT cord-333696-3ci9re9a 20 22 symptomatic symptomatic JJ cord-333696-3ci9re9a 20 23 presentation presentation NN cord-333696-3ci9re9a 20 24 of of IN cord-333696-3ci9re9a 20 25 that that DT cord-333696-3ci9re9a 20 26 virus virus NN cord-333696-3ci9re9a 20 27 . . . cord-333696-3ci9re9a 21 1 A a DT cord-333696-3ci9re9a 21 2 J j NN cord-333696-3ci9re9a 21 3 o o NN cord-333696-3ci9re9a 21 4 u u NN cord-333696-3ci9re9a 21 5 r r NN cord-333696-3ci9re9a 21 6 n n NN cord-333696-3ci9re9a 21 7 a a DT cord-333696-3ci9re9a 21 8 l l NN cord-333696-3ci9re9a 21 9 P p NN cord-333696-3ci9re9a 21 10 r r NN cord-333696-3ci9re9a 21 11 e e NN cord-333696-3ci9re9a 21 12 -p -p NN cord-333696-3ci9re9a 21 13 r r NN cord-333696-3ci9re9a 21 14 o o NN cord-333696-3ci9re9a 21 15 o o NN cord-333696-3ci9re9a 21 16 f f NN cord-333696-3ci9re9a 21 17 major major JJ cord-333696-3ci9re9a 21 18 factor factor NN cord-333696-3ci9re9a 21 19 that that WDT cord-333696-3ci9re9a 21 20 dictates dictate VBZ cord-333696-3ci9re9a 21 21 this this DT cord-333696-3ci9re9a 21 22 tissue tissue NN cord-333696-3ci9re9a 21 23 selectivity selectivity NN cord-333696-3ci9re9a 21 24 , , , cord-333696-3ci9re9a 21 25 is be VBZ cord-333696-3ci9re9a 21 26 the the DT cord-333696-3ci9re9a 21 27 virus virus NN cord-333696-3ci9re9a 21 28 's 's POS cord-333696-3ci9re9a 21 29 ability ability NN cord-333696-3ci9re9a 21 30 to to TO cord-333696-3ci9re9a 21 31 bind bind VB cord-333696-3ci9re9a 21 32 and and CC cord-333696-3ci9re9a 21 33 take take VB cord-333696-3ci9re9a 21 34 over over RP cord-333696-3ci9re9a 21 35 specific specific JJ cord-333696-3ci9re9a 21 36 host host NN cord-333696-3ci9re9a 21 37 cell cell NN cord-333696-3ci9re9a 21 38 surface surface NN cord-333696-3ci9re9a 21 39 receptors receptor NNS cord-333696-3ci9re9a 21 40 [ [ -LRB- cord-333696-3ci9re9a 21 41 9 9 CD cord-333696-3ci9re9a 21 42 ] ] -RRB- cord-333696-3ci9re9a 21 43 . . . cord-333696-3ci9re9a 22 1 Recent recent JJ cord-333696-3ci9re9a 22 2 research research NN cord-333696-3ci9re9a 22 3 on on IN cord-333696-3ci9re9a 22 4 SARS SARS NNP cord-333696-3ci9re9a 22 5 - - HYPH cord-333696-3ci9re9a 22 6 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 22 7 has have VBZ cord-333696-3ci9re9a 22 8 shown show VBN cord-333696-3ci9re9a 22 9 that that IN cord-333696-3ci9re9a 22 10 similarly similarly RB cord-333696-3ci9re9a 22 11 to to IN cord-333696-3ci9re9a 22 12 SARS SARS NNP cord-333696-3ci9re9a 22 13 - - HYPH cord-333696-3ci9re9a 22 14 CoV CoV NNP cord-333696-3ci9re9a 22 15 , , , cord-333696-3ci9re9a 22 16 this this DT cord-333696-3ci9re9a 22 17 virus virus NN cord-333696-3ci9re9a 22 18 can can MD cord-333696-3ci9re9a 22 19 invade invade VB cord-333696-3ci9re9a 22 20 tissues tissue NNS cord-333696-3ci9re9a 22 21 by by IN cord-333696-3ci9re9a 22 22 binding bind VBG cord-333696-3ci9re9a 22 23 to to IN cord-333696-3ci9re9a 22 24 the the DT cord-333696-3ci9re9a 22 25 angiotensin angiotensin NN cord-333696-3ci9re9a 22 26 - - HYPH cord-333696-3ci9re9a 22 27 converting convert VBG cord-333696-3ci9re9a 22 28 enzyme enzyme NN cord-333696-3ci9re9a 22 29 2 2 CD cord-333696-3ci9re9a 23 1 ( ( -LRB- cord-333696-3ci9re9a 23 2 ACE2 ACE2 NNP cord-333696-3ci9re9a 23 3 ) ) -RRB- cord-333696-3ci9re9a 23 4 receptor receptor NN cord-333696-3ci9re9a 23 5 on on IN cord-333696-3ci9re9a 23 6 certain certain JJ cord-333696-3ci9re9a 23 7 host host NN cord-333696-3ci9re9a 23 8 cells cell NNS cord-333696-3ci9re9a 23 9 ( ( -LRB- cord-333696-3ci9re9a 23 10 Figure figure NN cord-333696-3ci9re9a 23 11 1A 1a CD cord-333696-3ci9re9a 23 12 ) ) -RRB- cord-333696-3ci9re9a 23 13 [ [ -LRB- cord-333696-3ci9re9a 23 14 10 10 CD cord-333696-3ci9re9a 23 15 ] ] -RRB- cord-333696-3ci9re9a 23 16 . . . cord-333696-3ci9re9a 24 1 This this DT cord-333696-3ci9re9a 24 2 binding binding NN cord-333696-3ci9re9a 24 3 is be VBZ cord-333696-3ci9re9a 24 4 mediated mediate VBN cord-333696-3ci9re9a 24 5 by by IN cord-333696-3ci9re9a 24 6 the the DT cord-333696-3ci9re9a 24 7 spike spike NN cord-333696-3ci9re9a 24 8 protein protein NN cord-333696-3ci9re9a 24 9 found find VBD cord-333696-3ci9re9a 24 10 on on IN cord-333696-3ci9re9a 24 11 the the DT cord-333696-3ci9re9a 24 12 surface surface NN cord-333696-3ci9re9a 24 13 of of IN cord-333696-3ci9re9a 24 14 SARS SARS NNP cord-333696-3ci9re9a 24 15 - - HYPH cord-333696-3ci9re9a 24 16 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 24 17 and and CC cord-333696-3ci9re9a 24 18 was be VBD cord-333696-3ci9re9a 24 19 found find VBN cord-333696-3ci9re9a 24 20 to to TO cord-333696-3ci9re9a 24 21 have have VB cord-333696-3ci9re9a 24 22 up up IN cord-333696-3ci9re9a 24 23 to to TO cord-333696-3ci9re9a 24 24 20 20 CD cord-333696-3ci9re9a 24 25 times time NNS cord-333696-3ci9re9a 24 26 the the DT cord-333696-3ci9re9a 24 27 binding bind VBG cord-333696-3ci9re9a 24 28 affinity affinity NN cord-333696-3ci9re9a 24 29 of of IN cord-333696-3ci9re9a 24 30 SARS SARS NNP cord-333696-3ci9re9a 24 31 - - HYPH cord-333696-3ci9re9a 24 32 CoV CoV NNP cord-333696-3ci9re9a 24 33 [ [ -LRB- cord-333696-3ci9re9a 24 34 11 11 CD cord-333696-3ci9re9a 24 35 ] ] -RRB- cord-333696-3ci9re9a 24 36 . . . cord-333696-3ci9re9a 25 1 While while IN cord-333696-3ci9re9a 25 2 its -PRON- PRP$ cord-333696-3ci9re9a 25 3 mRNA mrna NN cord-333696-3ci9re9a 25 4 can can MD cord-333696-3ci9re9a 25 5 be be VB cord-333696-3ci9re9a 25 6 found find VBN cord-333696-3ci9re9a 25 7 in in IN cord-333696-3ci9re9a 25 8 virtually virtually RB cord-333696-3ci9re9a 25 9 all all DT cord-333696-3ci9re9a 25 10 body body NN cord-333696-3ci9re9a 25 11 tissues tissue NNS cord-333696-3ci9re9a 25 12 , , , cord-333696-3ci9re9a 25 13 the the DT cord-333696-3ci9re9a 25 14 ACE2 ACE2 NNP cord-333696-3ci9re9a 25 15 receptor receptor NN cord-333696-3ci9re9a 25 16 is be VBZ cord-333696-3ci9re9a 25 17 mostly mostly RB cord-333696-3ci9re9a 25 18 expressed express VBN cord-333696-3ci9re9a 25 19 in in IN cord-333696-3ci9re9a 25 20 lung lung NN cord-333696-3ci9re9a 25 21 alveolar alveolar NN cord-333696-3ci9re9a 25 22 epithelial epithelial JJ cord-333696-3ci9re9a 25 23 cells cell NNS cord-333696-3ci9re9a 25 24 , , , cord-333696-3ci9re9a 25 25 small small JJ cord-333696-3ci9re9a 25 26 intestine intestine NN cord-333696-3ci9re9a 25 27 enterocytes enterocyte NNS cord-333696-3ci9re9a 25 28 , , , cord-333696-3ci9re9a 25 29 vascular vascular JJ cord-333696-3ci9re9a 25 30 endothelial endothelial JJ cord-333696-3ci9re9a 25 31 cells cell NNS cord-333696-3ci9re9a 25 32 , , , cord-333696-3ci9re9a 25 33 in in IN cord-333696-3ci9re9a 25 34 addition addition NN cord-333696-3ci9re9a 25 35 to to IN cord-333696-3ci9re9a 25 36 airway airway NN cord-333696-3ci9re9a 25 37 epithelial epithelial JJ cord-333696-3ci9re9a 25 38 cells cell NNS cord-333696-3ci9re9a 25 39 , , , cord-333696-3ci9re9a 25 40 and and CC cord-333696-3ci9re9a 25 41 kidney kidney NN cord-333696-3ci9re9a 25 42 cells cell NNS cord-333696-3ci9re9a 25 43 [ [ -LRB- cord-333696-3ci9re9a 25 44 12 12 CD cord-333696-3ci9re9a 25 45 ] ] -RRB- cord-333696-3ci9re9a 25 46 . . . cord-333696-3ci9re9a 26 1 More more RBR cord-333696-3ci9re9a 26 2 recently recently RB cord-333696-3ci9re9a 26 3 , , , cord-333696-3ci9re9a 26 4 it -PRON- PRP cord-333696-3ci9re9a 26 5 was be VBD cord-333696-3ci9re9a 26 6 reported report VBN cord-333696-3ci9re9a 26 7 that that IN cord-333696-3ci9re9a 26 8 brain brain NN cord-333696-3ci9re9a 26 9 also also RB cord-333696-3ci9re9a 26 10 expresses express VBZ cord-333696-3ci9re9a 26 11 ACE2 ACE2 NNP cord-333696-3ci9re9a 26 12 receptors receptor NNS cord-333696-3ci9re9a 26 13 on on IN cord-333696-3ci9re9a 26 14 glial glial JJ cord-333696-3ci9re9a 26 15 cells cell NNS cord-333696-3ci9re9a 26 16 and and CC cord-333696-3ci9re9a 26 17 neurons neuron NNS cord-333696-3ci9re9a 26 18 and and CC cord-333696-3ci9re9a 26 19 this this DT cord-333696-3ci9re9a 26 20 is be VBZ cord-333696-3ci9re9a 26 21 most most RBS cord-333696-3ci9re9a 26 22 prominent prominent JJ cord-333696-3ci9re9a 26 23 in in IN cord-333696-3ci9re9a 26 24 the the DT cord-333696-3ci9re9a 26 25 brainstem brainstem NN cord-333696-3ci9re9a 26 26 , , , cord-333696-3ci9re9a 26 27 the the DT cord-333696-3ci9re9a 26 28 paraventricular paraventricular NNP cord-333696-3ci9re9a 26 29 nucleus nucleus NN cord-333696-3ci9re9a 26 30 ( ( -LRB- cord-333696-3ci9re9a 26 31 PVN PVN NNP cord-333696-3ci9re9a 26 32 ) ) -RRB- cord-333696-3ci9re9a 26 33 , , , cord-333696-3ci9re9a 26 34 nucleus nucleus NN cord-333696-3ci9re9a 26 35 tractus tractus NN cord-333696-3ci9re9a 26 36 solitarius solitarius NN cord-333696-3ci9re9a 26 37 ( ( -LRB- cord-333696-3ci9re9a 26 38 NTS NTS NNP cord-333696-3ci9re9a 26 39 ) ) -RRB- cord-333696-3ci9re9a 26 40 , , , cord-333696-3ci9re9a 26 41 and and CC cord-333696-3ci9re9a 26 42 the the DT cord-333696-3ci9re9a 26 43 rostral rostral JJ cord-333696-3ci9re9a 26 44 ventrolateral ventrolateral JJ cord-333696-3ci9re9a 26 45 medulla medulla NN cord-333696-3ci9re9a 26 46 which which WDT cord-333696-3ci9re9a 26 47 all all DT cord-333696-3ci9re9a 26 48 play play VBP cord-333696-3ci9re9a 26 49 a a DT cord-333696-3ci9re9a 26 50 role role NN cord-333696-3ci9re9a 26 51 in in IN cord-333696-3ci9re9a 26 52 cardiovascular cardiovascular JJ cord-333696-3ci9re9a 26 53 regulation regulation NN cord-333696-3ci9re9a 26 54 [ [ -LRB- cord-333696-3ci9re9a 26 55 13 13 CD cord-333696-3ci9re9a 26 56 ] ] -RRB- cord-333696-3ci9re9a 26 57 . . . cord-333696-3ci9re9a 27 1 On on IN cord-333696-3ci9re9a 27 2 the the DT cord-333696-3ci9re9a 27 3 other other JJ cord-333696-3ci9re9a 27 4 hand hand NN cord-333696-3ci9re9a 27 5 , , , cord-333696-3ci9re9a 27 6 viral viral JJ cord-333696-3ci9re9a 27 7 tissue tissue NN cord-333696-3ci9re9a 27 8 invasion invasion NN cord-333696-3ci9re9a 27 9 does do VBZ cord-333696-3ci9re9a 27 10 not not RB cord-333696-3ci9re9a 27 11 solely solely RB cord-333696-3ci9re9a 27 12 rely rely VB cord-333696-3ci9re9a 27 13 on on IN cord-333696-3ci9re9a 27 14 the the DT cord-333696-3ci9re9a 27 15 presence presence NN cord-333696-3ci9re9a 27 16 of of IN cord-333696-3ci9re9a 27 17 certain certain JJ cord-333696-3ci9re9a 27 18 receptors receptor NNS cord-333696-3ci9re9a 27 19 and and CC cord-333696-3ci9re9a 27 20 the the DT cord-333696-3ci9re9a 27 21 ability ability NN cord-333696-3ci9re9a 27 22 to to TO cord-333696-3ci9re9a 27 23 hijack hijack VB cord-333696-3ci9re9a 27 24 them -PRON- PRP cord-333696-3ci9re9a 27 25 . . . cord-333696-3ci9re9a 28 1 Recent recent JJ cord-333696-3ci9re9a 28 2 studies study NNS cord-333696-3ci9re9a 28 3 on on IN cord-333696-3ci9re9a 28 4 the the DT cord-333696-3ci9re9a 28 5 novel novel JJ cord-333696-3ci9re9a 28 6 coronavirus coronavirus NN cord-333696-3ci9re9a 28 7 have have VBP cord-333696-3ci9re9a 28 8 shown show VBN cord-333696-3ci9re9a 28 9 that that IN cord-333696-3ci9re9a 28 10 , , , cord-333696-3ci9re9a 28 11 like like IN cord-333696-3ci9re9a 28 12 its -PRON- PRP$ cord-333696-3ci9re9a 28 13 predecessors predecessor NNS cord-333696-3ci9re9a 28 14 , , , cord-333696-3ci9re9a 28 15 a a DT cord-333696-3ci9re9a 28 16 substantial substantial JJ cord-333696-3ci9re9a 28 17 part part NN cord-333696-3ci9re9a 28 18 of of IN cord-333696-3ci9re9a 28 19 its -PRON- PRP$ cord-333696-3ci9re9a 28 20 symptomatology symptomatology NN cord-333696-3ci9re9a 28 21 can can MD cord-333696-3ci9re9a 28 22 be be VB cord-333696-3ci9re9a 28 23 explained explain VBN cord-333696-3ci9re9a 28 24 by by IN cord-333696-3ci9re9a 28 25 the the DT cord-333696-3ci9re9a 28 26 cytokine cytokine NN cord-333696-3ci9re9a 28 27 storm storm NN cord-333696-3ci9re9a 28 28 it -PRON- PRP cord-333696-3ci9re9a 28 29 triggers trigger VBZ cord-333696-3ci9re9a 28 30 , , , cord-333696-3ci9re9a 28 31 leading lead VBG cord-333696-3ci9re9a 28 32 to to IN cord-333696-3ci9re9a 28 33 a a DT cord-333696-3ci9re9a 28 34 systemic systemic JJ cord-333696-3ci9re9a 28 35 inflammatory inflammatory JJ cord-333696-3ci9re9a 28 36 response response NN cord-333696-3ci9re9a 28 37 syndrome syndrome NN cord-333696-3ci9re9a 28 38 ( ( -LRB- cord-333696-3ci9re9a 28 39 SIRS sirs UH cord-333696-3ci9re9a 28 40 ) ) -RRB- cord-333696-3ci9re9a 28 41 or or CC cord-333696-3ci9re9a 28 42 SIRS SIRS NNP cord-333696-3ci9re9a 28 43 - - HYPH cord-333696-3ci9re9a 28 44 like like JJ cord-333696-3ci9re9a 28 45 phenomenon phenomenon NN cord-333696-3ci9re9a 28 46 ( ( -LRB- cord-333696-3ci9re9a 28 47 Figure figure NN cord-333696-3ci9re9a 28 48 1B 1b CD cord-333696-3ci9re9a 28 49 ) ) -RRB- cord-333696-3ci9re9a 28 50 [ [ -LRB- cord-333696-3ci9re9a 28 51 14 14 CD cord-333696-3ci9re9a 28 52 , , , cord-333696-3ci9re9a 28 53 15 15 CD cord-333696-3ci9re9a 28 54 ] ] -RRB- cord-333696-3ci9re9a 28 55 . . . cord-333696-3ci9re9a 29 1 This this DT cord-333696-3ci9re9a 29 2 inflammation inflammation NN cord-333696-3ci9re9a 29 3 is be VBZ cord-333696-3ci9re9a 29 4 mediated mediate VBN cord-333696-3ci9re9a 29 5 by by IN cord-333696-3ci9re9a 29 6 interleukins interleukin NNS cord-333696-3ci9re9a 29 7 ( ( -LRB- cord-333696-3ci9re9a 29 8 IL-6 IL-6 NNP cord-333696-3ci9re9a 29 9 and and CC cord-333696-3ci9re9a 29 10 IL-8 IL-8 NNP cord-333696-3ci9re9a 29 11 ) ) -RRB- cord-333696-3ci9re9a 29 12 released release VBN cord-333696-3ci9re9a 29 13 by by IN cord-333696-3ci9re9a 29 14 monocytes monocyte NNS cord-333696-3ci9re9a 29 15 and and CC cord-333696-3ci9re9a 29 16 macrophages macrophage NNS cord-333696-3ci9re9a 29 17 to to TO cord-333696-3ci9re9a 29 18 stimulate stimulate VB cord-333696-3ci9re9a 29 19 other other JJ cord-333696-3ci9re9a 29 20 monocytes monocyte NNS cord-333696-3ci9re9a 29 21 and and CC cord-333696-3ci9re9a 29 22 both both DT cord-333696-3ci9re9a 29 23 B B NNP cord-333696-3ci9re9a 29 24 and and CC cord-333696-3ci9re9a 29 25 T t NN cord-333696-3ci9re9a 29 26 lymphocytes lymphocyte NNS cord-333696-3ci9re9a 29 27 , , , cord-333696-3ci9re9a 29 28 in in IN cord-333696-3ci9re9a 29 29 addition addition NN cord-333696-3ci9re9a 29 30 to to IN cord-333696-3ci9re9a 29 31 monocyte monocyte NNP cord-333696-3ci9re9a 29 32 chemoattractant chemoattractant NNP cord-333696-3ci9re9a 29 33 protein-1 protein-1 NNP cord-333696-3ci9re9a 29 34 ( ( -LRB- cord-333696-3ci9re9a 29 35 MCP-1 MCP-1 NNP cord-333696-3ci9re9a 29 36 ) ) -RRB- cord-333696-3ci9re9a 29 37 , , , cord-333696-3ci9re9a 29 38 a a DT cord-333696-3ci9re9a 29 39 chemokine chemokine NN cord-333696-3ci9re9a 29 40 responsible responsible JJ cord-333696-3ci9re9a 29 41 for for IN cord-333696-3ci9re9a 29 42 the the DT cord-333696-3ci9re9a 29 43 transmigration transmigration NN cord-333696-3ci9re9a 29 44 of of IN cord-333696-3ci9re9a 29 45 the the DT cord-333696-3ci9re9a 29 46 monocytes monocyte NNS cord-333696-3ci9re9a 29 47 across across IN cord-333696-3ci9re9a 29 48 the the DT cord-333696-3ci9re9a 29 49 blood blood NN cord-333696-3ci9re9a 29 50 - - HYPH cord-333696-3ci9re9a 29 51 brain brain NN cord-333696-3ci9re9a 29 52 barrier barrier NN cord-333696-3ci9re9a 29 53 ( ( -LRB- cord-333696-3ci9re9a 29 54 BBB BBB NNP cord-333696-3ci9re9a 29 55 ) ) -RRB- cord-333696-3ci9re9a 29 56 [ [ -LRB- cord-333696-3ci9re9a 29 57 16 16 CD cord-333696-3ci9re9a 29 58 , , , cord-333696-3ci9re9a 29 59 17 17 CD cord-333696-3ci9re9a 29 60 ] ] -RRB- cord-333696-3ci9re9a 29 61 . . . cord-333696-3ci9re9a 30 1 Thus thus RB cord-333696-3ci9re9a 30 2 , , , cord-333696-3ci9re9a 30 3 this this DT cord-333696-3ci9re9a 30 4 can can MD cord-333696-3ci9re9a 30 5 then then RB cord-333696-3ci9re9a 30 6 lead lead VB cord-333696-3ci9re9a 30 7 to to IN cord-333696-3ci9re9a 30 8 the the DT cord-333696-3ci9re9a 30 9 inflammation inflammation NN cord-333696-3ci9re9a 30 10 of of IN cord-333696-3ci9re9a 30 11 the the DT cord-333696-3ci9re9a 30 12 BBB BBB NNP cord-333696-3ci9re9a 30 13 and and CC cord-333696-3ci9re9a 30 14 increase increase VB cord-333696-3ci9re9a 30 15 its -PRON- PRP$ cord-333696-3ci9re9a 30 16 permeability permeability NN cord-333696-3ci9re9a 30 17 which which WDT cord-333696-3ci9re9a 30 18 facilitates facilitate VBZ cord-333696-3ci9re9a 30 19 the the DT cord-333696-3ci9re9a 30 20 passage passage NN cord-333696-3ci9re9a 30 21 of of IN cord-333696-3ci9re9a 30 22 more more JJR cord-333696-3ci9re9a 30 23 inflammatory inflammatory JJ cord-333696-3ci9re9a 30 24 cytokines cytokine NNS cord-333696-3ci9re9a 30 25 and and CC cord-333696-3ci9re9a 30 26 chemokines chemokine NNS cord-333696-3ci9re9a 30 27 into into IN cord-333696-3ci9re9a 30 28 the the DT cord-333696-3ci9re9a 30 29 brain brain NN cord-333696-3ci9re9a 30 30 and and CC cord-333696-3ci9re9a 30 31 can can MD cord-333696-3ci9re9a 30 32 exacerbate exacerbate VB cord-333696-3ci9re9a 30 33 the the DT cord-333696-3ci9re9a 30 34 neuroinflammation neuroinflammation NN cord-333696-3ci9re9a 30 35 and and CC cord-333696-3ci9re9a 30 36 neurological neurological JJ cord-333696-3ci9re9a 30 37 symptoms symptom NNS cord-333696-3ci9re9a 30 38 experienced experience VBN cord-333696-3ci9re9a 30 39 by by IN cord-333696-3ci9re9a 30 40 the the DT cord-333696-3ci9re9a 30 41 patient patient NN cord-333696-3ci9re9a 30 42 [ [ -LRB- cord-333696-3ci9re9a 30 43 18 18 CD cord-333696-3ci9re9a 30 44 ] ] -RRB- cord-333696-3ci9re9a 30 45 . . . cord-333696-3ci9re9a 31 1 Additionally additionally RB cord-333696-3ci9re9a 31 2 , , , cord-333696-3ci9re9a 31 3 during during IN cord-333696-3ci9re9a 31 4 previous previous JJ cord-333696-3ci9re9a 31 5 coronavirus coronavirus NN cord-333696-3ci9re9a 31 6 epidemics epidemic NNS cord-333696-3ci9re9a 31 7 ( ( -LRB- cord-333696-3ci9re9a 31 8 SARS SARS NNP cord-333696-3ci9re9a 31 9 - - HYPH cord-333696-3ci9re9a 31 10 CoV CoV NNP cord-333696-3ci9re9a 31 11 and and CC cord-333696-3ci9re9a 31 12 MERS MERS NNP cord-333696-3ci9re9a 31 13 - - HYPH cord-333696-3ci9re9a 31 14 CoV CoV NNP cord-333696-3ci9re9a 31 15 ) ) -RRB- cord-333696-3ci9re9a 31 16 , , , cord-333696-3ci9re9a 31 17 animal animal NN cord-333696-3ci9re9a 31 18 studies study NNS cord-333696-3ci9re9a 31 19 on on IN cord-333696-3ci9re9a 31 20 transgenic transgenic JJ cord-333696-3ci9re9a 31 21 mice mouse NNS cord-333696-3ci9re9a 31 22 showed show VBD cord-333696-3ci9re9a 31 23 that that IN cord-333696-3ci9re9a 31 24 both both DT cord-333696-3ci9re9a 31 25 of of IN cord-333696-3ci9re9a 31 26 these these DT cord-333696-3ci9re9a 31 27 viruses virus NNS cord-333696-3ci9re9a 31 28 were be VBD cord-333696-3ci9re9a 31 29 able able JJ cord-333696-3ci9re9a 31 30 to to TO cord-333696-3ci9re9a 31 31 reach reach VB cord-333696-3ci9re9a 31 32 the the DT cord-333696-3ci9re9a 31 33 brain brain NN cord-333696-3ci9re9a 31 34 when when WRB cord-333696-3ci9re9a 31 35 neuroinvasion neuroinvasion NNP cord-333696-3ci9re9a 31 36 [ [ -LRB- cord-333696-3ci9re9a 31 37 22 22 CD cord-333696-3ci9re9a 31 38 ] ] -RRB- cord-333696-3ci9re9a 31 39 . . . cord-333696-3ci9re9a 32 1 Finally finally RB cord-333696-3ci9re9a 32 2 , , , cord-333696-3ci9re9a 32 3 it -PRON- PRP cord-333696-3ci9re9a 32 4 is be VBZ cord-333696-3ci9re9a 32 5 important important JJ cord-333696-3ci9re9a 32 6 to to TO cord-333696-3ci9re9a 32 7 mention mention VB cord-333696-3ci9re9a 32 8 that that IN cord-333696-3ci9re9a 32 9 the the DT cord-333696-3ci9re9a 32 10 virus virus NN cord-333696-3ci9re9a 32 11 can can MD cord-333696-3ci9re9a 32 12 also also RB cord-333696-3ci9re9a 32 13 cause cause VB cord-333696-3ci9re9a 32 14 CNS CNS NNP cord-333696-3ci9re9a 32 15 damage damage NN cord-333696-3ci9re9a 32 16 and and CC cord-333696-3ci9re9a 32 17 neurological neurological JJ cord-333696-3ci9re9a 32 18 symptoms symptom NNS cord-333696-3ci9re9a 32 19 without without IN cord-333696-3ci9re9a 32 20 invading invade VBG cord-333696-3ci9re9a 32 21 the the DT cord-333696-3ci9re9a 32 22 brain brain NN cord-333696-3ci9re9a 32 23 itself -PRON- PRP cord-333696-3ci9re9a 32 24 . . . cord-333696-3ci9re9a 33 1 As as IN cord-333696-3ci9re9a 33 2 respiratory respiratory JJ cord-333696-3ci9re9a 33 3 viruses virus NNS cord-333696-3ci9re9a 33 4 invade invade VBP cord-333696-3ci9re9a 33 5 the the DT cord-333696-3ci9re9a 33 6 lungs lung NNS cord-333696-3ci9re9a 33 7 and and CC cord-333696-3ci9re9a 33 8 cause cause VB cord-333696-3ci9re9a 33 9 inflammation inflammation NN cord-333696-3ci9re9a 33 10 , , , cord-333696-3ci9re9a 33 11 this this DT cord-333696-3ci9re9a 33 12 leads lead VBZ cord-333696-3ci9re9a 33 13 to to IN cord-333696-3ci9re9a 33 14 alveolar alveolar NN cord-333696-3ci9re9a 33 15 and and CC cord-333696-3ci9re9a 33 16 lung lung NN cord-333696-3ci9re9a 33 17 tissue tissue NN cord-333696-3ci9re9a 33 18 damage damage NN cord-333696-3ci9re9a 33 19 . . . cord-333696-3ci9re9a 34 1 Inflammation inflammation NN cord-333696-3ci9re9a 34 2 and and CC cord-333696-3ci9re9a 34 3 edema edema NN cord-333696-3ci9re9a 34 4 affect affect VBP cord-333696-3ci9re9a 34 5 the the DT cord-333696-3ci9re9a 34 6 oxygen oxygen NN cord-333696-3ci9re9a 34 7 exchange exchange NN cord-333696-3ci9re9a 34 8 that that WDT cord-333696-3ci9re9a 34 9 happens happen VBZ cord-333696-3ci9re9a 34 10 at at IN cord-333696-3ci9re9a 34 11 the the DT cord-333696-3ci9re9a 34 12 alveolar alveolar NN cord-333696-3ci9re9a 34 13 - - HYPH cord-333696-3ci9re9a 34 14 capillary capillary NN cord-333696-3ci9re9a 34 15 interface interface NN cord-333696-3ci9re9a 34 16 leading lead VBG cord-333696-3ci9re9a 34 17 to to IN cord-333696-3ci9re9a 34 18 hypoxemia hypoxemia NN cord-333696-3ci9re9a 34 19 and and CC cord-333696-3ci9re9a 34 20 subsequently subsequently RB cord-333696-3ci9re9a 34 21 brain brain NN cord-333696-3ci9re9a 34 22 hypoxia hypoxia NN cord-333696-3ci9re9a 34 23 with with IN cord-333696-3ci9re9a 34 24 vasodilation vasodilation NN cord-333696-3ci9re9a 34 25 , , , cord-333696-3ci9re9a 34 26 hyperemia hyperemia NN cord-333696-3ci9re9a 34 27 and and CC cord-333696-3ci9re9a 34 28 brain brain NN cord-333696-3ci9re9a 34 29 edema edema NN cord-333696-3ci9re9a 35 1 ( ( -LRB- cord-333696-3ci9re9a 35 2 Figure figure NN cord-333696-3ci9re9a 35 3 2 2 CD cord-333696-3ci9re9a 35 4 ) ) -RRB- cord-333696-3ci9re9a 36 1 [ [ -LRB- cord-333696-3ci9re9a 36 2 23 23 CD cord-333696-3ci9re9a 36 3 ] ] -RRB- cord-333696-3ci9re9a 36 4 . . . cord-333696-3ci9re9a 37 1 This this DT cord-333696-3ci9re9a 37 2 would would MD cord-333696-3ci9re9a 37 3 then then RB cord-333696-3ci9re9a 37 4 manifest manifest VB cord-333696-3ci9re9a 37 5 itself -PRON- PRP cord-333696-3ci9re9a 37 6 starting start VBG cord-333696-3ci9re9a 37 7 with with IN cord-333696-3ci9re9a 37 8 headaches headache NNS cord-333696-3ci9re9a 37 9 and and CC cord-333696-3ci9re9a 37 10 , , , cord-333696-3ci9re9a 37 11 if if IN cord-333696-3ci9re9a 37 12 kept keep VBN cord-333696-3ci9re9a 37 13 unchecked unchecked JJ cord-333696-3ci9re9a 37 14 , , , cord-333696-3ci9re9a 37 15 could could MD cord-333696-3ci9re9a 37 16 cause cause VB cord-333696-3ci9re9a 37 17 a a DT cord-333696-3ci9re9a 37 18 change change NN cord-333696-3ci9re9a 37 19 in in IN cord-333696-3ci9re9a 37 20 the the DT cord-333696-3ci9re9a 37 21 level level NN cord-333696-3ci9re9a 37 22 of of IN cord-333696-3ci9re9a 37 23 consciousness consciousness NN cord-333696-3ci9re9a 37 24 and and CC cord-333696-3ci9re9a 37 25 even even RB cord-333696-3ci9re9a 37 26 coma coma NN cord-333696-3ci9re9a 37 27 [ [ -LRB- cord-333696-3ci9re9a 37 28 23 23 CD cord-333696-3ci9re9a 37 29 ] ] -RRB- cord-333696-3ci9re9a 37 30 . . . cord-333696-3ci9re9a 38 1 Being be VBG cord-333696-3ci9re9a 38 2 a a DT cord-333696-3ci9re9a 38 3 respiratory respiratory JJ cord-333696-3ci9re9a 38 4 virus virus NN cord-333696-3ci9re9a 38 5 itself -PRON- PRP cord-333696-3ci9re9a 38 6 , , , cord-333696-3ci9re9a 38 7 SARS SARS NNP cord-333696-3ci9re9a 38 8 - - HYPH cord-333696-3ci9re9a 38 9 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 38 10 has have VBZ cord-333696-3ci9re9a 38 11 been be VBN cord-333696-3ci9re9a 38 12 shown show VBN cord-333696-3ci9re9a 38 13 to to TO cord-333696-3ci9re9a 38 14 cause cause VB cord-333696-3ci9re9a 38 15 significant significant JJ cord-333696-3ci9re9a 38 16 hypoxemia hypoxemia NN cord-333696-3ci9re9a 38 17 in in IN cord-333696-3ci9re9a 38 18 many many JJ cord-333696-3ci9re9a 38 19 of of IN cord-333696-3ci9re9a 38 20 the the DT cord-333696-3ci9re9a 38 21 patients patient NNS cord-333696-3ci9re9a 38 22 [ [ -LRB- cord-333696-3ci9re9a 38 23 24 24 CD cord-333696-3ci9re9a 38 24 ] ] -RRB- cord-333696-3ci9re9a 38 25 and and CC cord-333696-3ci9re9a 38 26 hence hence RB cord-333696-3ci9re9a 38 27 , , , cord-333696-3ci9re9a 38 28 this this DT cord-333696-3ci9re9a 38 29 possible possible JJ cord-333696-3ci9re9a 38 30 pathway pathway NN cord-333696-3ci9re9a 38 31 of of IN cord-333696-3ci9re9a 38 32 brain brain NN cord-333696-3ci9re9a 38 33 injury injury NN cord-333696-3ci9re9a 38 34 remains remain VBZ cord-333696-3ci9re9a 38 35 a a DT cord-333696-3ci9re9a 38 36 factor factor NN cord-333696-3ci9re9a 38 37 in in IN cord-333696-3ci9re9a 38 38 its -PRON- PRP$ cord-333696-3ci9re9a 38 39 symptomatic symptomatic JJ cord-333696-3ci9re9a 38 40 profile profile NN cord-333696-3ci9re9a 38 41 . . . cord-333696-3ci9re9a 39 1 There there EX cord-333696-3ci9re9a 39 2 is be VBZ cord-333696-3ci9re9a 39 3 still still RB cord-333696-3ci9re9a 39 4 a a DT cord-333696-3ci9re9a 39 5 debate debate NN cord-333696-3ci9re9a 39 6 regarding regard VBG cord-333696-3ci9re9a 39 7 the the DT cord-333696-3ci9re9a 39 8 exact exact JJ cord-333696-3ci9re9a 39 9 role role NN cord-333696-3ci9re9a 39 10 of of IN cord-333696-3ci9re9a 39 11 brainstem brainstem NN cord-333696-3ci9re9a 39 12 invasion invasion NN cord-333696-3ci9re9a 39 13 by by IN cord-333696-3ci9re9a 39 14 the the DT cord-333696-3ci9re9a 39 15 virus virus NN cord-333696-3ci9re9a 39 16 in in IN cord-333696-3ci9re9a 39 17 causing cause VBG cord-333696-3ci9re9a 39 18 respiratory respiratory JJ cord-333696-3ci9re9a 39 19 failure failure NN cord-333696-3ci9re9a 39 20 in in IN cord-333696-3ci9re9a 39 21 COVID-19 covid-19 JJ cord-333696-3ci9re9a 39 22 patients patient NNS cord-333696-3ci9re9a 39 23 . . . cord-333696-3ci9re9a 40 1 Li Li NNP cord-333696-3ci9re9a 40 2 and and CC cord-333696-3ci9re9a 40 3 colleagues colleague NNS cord-333696-3ci9re9a 40 4 ( ( -LRB- cord-333696-3ci9re9a 40 5 2020 2020 CD cord-333696-3ci9re9a 40 6 ) ) -RRB- cord-333696-3ci9re9a 40 7 have have VBP cord-333696-3ci9re9a 40 8 suggested suggest VBN cord-333696-3ci9re9a 40 9 that that IN cord-333696-3ci9re9a 40 10 SARS SARS NNP cord-333696-3ci9re9a 40 11 - - HYPH cord-333696-3ci9re9a 40 12 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 40 13 can can MD cord-333696-3ci9re9a 40 14 enter enter VB cord-333696-3ci9re9a 40 15 the the DT cord-333696-3ci9re9a 40 16 brain brain NN cord-333696-3ci9re9a 40 17 , , , cord-333696-3ci9re9a 40 18 and and CC cord-333696-3ci9re9a 40 19 it -PRON- PRP cord-333696-3ci9re9a 40 20 might may MD cord-333696-3ci9re9a 40 21 be be VB cord-333696-3ci9re9a 40 22 the the DT cord-333696-3ci9re9a 40 23 cause cause NN cord-333696-3ci9re9a 40 24 of of IN cord-333696-3ci9re9a 40 25 the the DT cord-333696-3ci9re9a 40 26 respiratory respiratory JJ cord-333696-3ci9re9a 40 27 failure failure NN cord-333696-3ci9re9a 40 28 in in IN cord-333696-3ci9re9a 40 29 patients patient NNS cord-333696-3ci9re9a 40 30 with with IN cord-333696-3ci9re9a 40 31 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 40 32 [ [ -LRB- cord-333696-3ci9re9a 40 33 25 25 CD cord-333696-3ci9re9a 40 34 ] ] -RRB- cord-333696-3ci9re9a 40 35 . . . cord-333696-3ci9re9a 41 1 On on IN cord-333696-3ci9re9a 41 2 the the DT cord-333696-3ci9re9a 41 3 other other JJ cord-333696-3ci9re9a 41 4 hand hand NN cord-333696-3ci9re9a 41 5 , , , cord-333696-3ci9re9a 41 6 Turtle turtle NN cord-333696-3ci9re9a 41 7 ( ( -LRB- cord-333696-3ci9re9a 41 8 2020 2020 CD cord-333696-3ci9re9a 41 9 ) ) -RRB- cord-333696-3ci9re9a 41 10 has have VBZ cord-333696-3ci9re9a 41 11 reported report VBN cord-333696-3ci9re9a 41 12 that that IN cord-333696-3ci9re9a 41 13 respiratory respiratory JJ cord-333696-3ci9re9a 41 14 failure failure NN cord-333696-3ci9re9a 41 15 alone alone RB cord-333696-3ci9re9a 41 16 does do VBZ cord-333696-3ci9re9a 41 17 not not RB cord-333696-3ci9re9a 41 18 suggest suggest VB cord-333696-3ci9re9a 41 19 central central JJ cord-333696-3ci9re9a 41 20 nervous nervous JJ cord-333696-3ci9re9a 41 21 system system NN cord-333696-3ci9re9a 41 22 invasion invasion NN cord-333696-3ci9re9a 41 23 by by IN cord-333696-3ci9re9a 41 24 SARS SARS NNP cord-333696-3ci9re9a 41 25 - - HYPH cord-333696-3ci9re9a 41 26 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 41 27 . . . cord-333696-3ci9re9a 42 1 Turtle turtle NN cord-333696-3ci9re9a 42 2 relied rely VBD cord-333696-3ci9re9a 42 3 on on IN cord-333696-3ci9re9a 42 4 certain certain JJ cord-333696-3ci9re9a 42 5 points point NNS cord-333696-3ci9re9a 42 6 to to TO cord-333696-3ci9re9a 42 7 support support VB cord-333696-3ci9re9a 42 8 his -PRON- PRP$ cord-333696-3ci9re9a 42 9 conclusion conclusion NN cord-333696-3ci9re9a 42 10 ; ; : cord-333696-3ci9re9a 42 11 patients patient NNS cord-333696-3ci9re9a 42 12 with with IN cord-333696-3ci9re9a 42 13 pneumonia pneumonia NN cord-333696-3ci9re9a 42 14 typically typically RB cord-333696-3ci9re9a 42 15 develop develop VBP cord-333696-3ci9re9a 42 16 hypoxic hypoxic JJ cord-333696-3ci9re9a 42 17 , , , cord-333696-3ci9re9a 42 18 or or CC cord-333696-3ci9re9a 42 19 type type NN cord-333696-3ci9re9a 42 20 1 1 CD cord-333696-3ci9re9a 42 21 respiratory respiratory JJ cord-333696-3ci9re9a 42 22 failure failure NN cord-333696-3ci9re9a 42 23 , , , cord-333696-3ci9re9a 42 24 with with IN cord-333696-3ci9re9a 42 25 low low JJ cord-333696-3ci9re9a 42 26 CO2 CO2 NNP cord-333696-3ci9re9a 42 27 levels level NNS cord-333696-3ci9re9a 42 28 and and CC cord-333696-3ci9re9a 42 29 a a DT cord-333696-3ci9re9a 42 30 raised raise VBN cord-333696-3ci9re9a 42 31 respiratory respiratory JJ cord-333696-3ci9re9a 42 32 rate rate NN cord-333696-3ci9re9a 42 33 , , , cord-333696-3ci9re9a 42 34 while while IN cord-333696-3ci9re9a 42 35 brain brain NN cord-333696-3ci9re9a 42 36 failure failure NN cord-333696-3ci9re9a 42 37 typically typically RB cord-333696-3ci9re9a 42 38 leads lead VBZ cord-333696-3ci9re9a 42 39 to to TO cord-333696-3ci9re9a 42 40 type type VB cord-333696-3ci9re9a 42 41 2 2 CD cord-333696-3ci9re9a 42 42 respiratory respiratory JJ cord-333696-3ci9re9a 42 43 failure failure NN cord-333696-3ci9re9a 42 44 and and CC cord-333696-3ci9re9a 42 45 involves involve VBZ cord-333696-3ci9re9a 42 46 low low JJ cord-333696-3ci9re9a 42 47 oxygen oxygen NN cord-333696-3ci9re9a 42 48 , , , cord-333696-3ci9re9a 42 49 high high JJ cord-333696-3ci9re9a 42 50 CO2 co2 NN cord-333696-3ci9re9a 42 51 and and CC cord-333696-3ci9re9a 42 52 reduced reduce VBN cord-333696-3ci9re9a 42 53 respiratory respiratory JJ cord-333696-3ci9re9a 42 54 rate rate NN cord-333696-3ci9re9a 42 55 . . . cord-333696-3ci9re9a 43 1 He -PRON- PRP cord-333696-3ci9re9a 43 2 mentioned mention VBD cord-333696-3ci9re9a 43 3 that that IN cord-333696-3ci9re9a 43 4 these these DT cord-333696-3ci9re9a 43 5 manifestations manifestation NNS cord-333696-3ci9re9a 43 6 of of IN cord-333696-3ci9re9a 43 7 type type NN cord-333696-3ci9re9a 43 8 2 2 CD cord-333696-3ci9re9a 43 9 respiratory respiratory JJ cord-333696-3ci9re9a 43 10 failure failure NN cord-333696-3ci9re9a 43 11 were be VBD cord-333696-3ci9re9a 43 12 not not RB cord-333696-3ci9re9a 43 13 reported report VBN cord-333696-3ci9re9a 43 14 to to IN cord-333696-3ci9re9a 43 15 any any DT cord-333696-3ci9re9a 43 16 great great JJ cord-333696-3ci9re9a 43 17 degree degree NN cord-333696-3ci9re9a 43 18 in in IN cord-333696-3ci9re9a 43 19 any any DT cord-333696-3ci9re9a 43 20 of of IN cord-333696-3ci9re9a 43 21 the the DT cord-333696-3ci9re9a 43 22 case case NN cord-333696-3ci9re9a 43 23 series series NN cord-333696-3ci9re9a 43 24 of of IN cord-333696-3ci9re9a 43 25 patients patient NNS cord-333696-3ci9re9a 43 26 from from IN cord-333696-3ci9re9a 43 27 China China NNP cord-333696-3ci9re9a 43 28 9 9 CD cord-333696-3ci9re9a 43 29 . . . cord-333696-3ci9re9a 44 1 He -PRON- PRP cord-333696-3ci9re9a 44 2 also also RB cord-333696-3ci9re9a 44 3 stated state VBD cord-333696-3ci9re9a 44 4 that that IN cord-333696-3ci9re9a 44 5 if if IN cord-333696-3ci9re9a 44 6 the the DT cord-333696-3ci9re9a 44 7 neuroinvasion neuroinvasion NN cord-333696-3ci9re9a 44 8 of of IN cord-333696-3ci9re9a 44 9 the the DT cord-333696-3ci9re9a 44 10 virus virus NN cord-333696-3ci9re9a 44 11 would would MD cord-333696-3ci9re9a 44 12 be be VB cord-333696-3ci9re9a 44 13 the the DT cord-333696-3ci9re9a 44 14 cause cause NN cord-333696-3ci9re9a 44 15 of of IN cord-333696-3ci9re9a 44 16 respiratory respiratory JJ cord-333696-3ci9re9a 44 17 failure failure NN cord-333696-3ci9re9a 44 18 , , , cord-333696-3ci9re9a 44 19 the the DT cord-333696-3ci9re9a 44 20 virus virus NN cord-333696-3ci9re9a 44 21 should should MD cord-333696-3ci9re9a 44 22 be be VB cord-333696-3ci9re9a 44 23 detected detect VBN cord-333696-3ci9re9a 44 24 in in IN cord-333696-3ci9re9a 44 25 the the DT cord-333696-3ci9re9a 44 26 cerebrospinal cerebrospinal JJ cord-333696-3ci9re9a 44 27 fluid fluid NN cord-333696-3ci9re9a 44 28 of of IN cord-333696-3ci9re9a 44 29 these these DT cord-333696-3ci9re9a 44 30 patients patient NNS cord-333696-3ci9re9a 44 31 [ [ -LRB- cord-333696-3ci9re9a 44 32 26 26 CD cord-333696-3ci9re9a 44 33 , , , cord-333696-3ci9re9a 44 34 27 27 CD cord-333696-3ci9re9a 44 35 ] ] -RRB- cord-333696-3ci9re9a 44 36 . . . cord-333696-3ci9re9a 45 1 Recently recently RB cord-333696-3ci9re9a 45 2 , , , cord-333696-3ci9re9a 45 3 Olds Olds NNP cord-333696-3ci9re9a 45 4 & & CC cord-333696-3ci9re9a 45 5 Kabbani Kabbani NNP cord-333696-3ci9re9a 45 6 ( ( -LRB- cord-333696-3ci9re9a 45 7 2020 2020 CD cord-333696-3ci9re9a 45 8 ) ) -RRB- cord-333696-3ci9re9a 45 9 raised raise VBD cord-333696-3ci9re9a 45 10 the the DT cord-333696-3ci9re9a 45 11 question question NN cord-333696-3ci9re9a 45 12 of of IN cord-333696-3ci9re9a 45 13 nicotine nicotine NN cord-333696-3ci9re9a 45 14 associated associate VBN cord-333696-3ci9re9a 45 15 neurological neurological JJ cord-333696-3ci9re9a 45 16 comorbidity comorbidity NN cord-333696-3ci9re9a 45 17 in in IN cord-333696-3ci9re9a 45 18 COVID19 covid19 NN cord-333696-3ci9re9a 45 19 patients patient NNS cord-333696-3ci9re9a 45 20 depending depend VBG cord-333696-3ci9re9a 45 21 on on IN cord-333696-3ci9re9a 45 22 published publish VBN cord-333696-3ci9re9a 45 23 evidence evidence NN cord-333696-3ci9re9a 45 24 that that IN cord-333696-3ci9re9a 45 25 the the DT cord-333696-3ci9re9a 45 26 viral viral JJ cord-333696-3ci9re9a 45 27 target target NN cord-333696-3ci9re9a 45 28 receptor receptor NN cord-333696-3ci9re9a 45 29 J J NNP cord-333696-3ci9re9a 45 30 o o NN cord-333696-3ci9re9a 45 31 u u NN cord-333696-3ci9re9a 45 32 r r NN cord-333696-3ci9re9a 45 33 n n NN cord-333696-3ci9re9a 45 34 a a DT cord-333696-3ci9re9a 45 35 l l NN cord-333696-3ci9re9a 45 36 P p NN cord-333696-3ci9re9a 45 37 r r NN cord-333696-3ci9re9a 45 38 e e NN cord-333696-3ci9re9a 45 39 -p -p NN cord-333696-3ci9re9a 46 1 r r NN cord-333696-3ci9re9a 46 2 o o NN cord-333696-3ci9re9a 46 3 o o NN cord-333696-3ci9re9a 46 4 f f NN cord-333696-3ci9re9a 46 5 ACE2 ACE2 NNP cord-333696-3ci9re9a 46 6 is be VBZ cord-333696-3ci9re9a 46 7 expressed express VBN cord-333696-3ci9re9a 46 8 in in IN cord-333696-3ci9re9a 46 9 the the DT cord-333696-3ci9re9a 46 10 brain brain NN cord-333696-3ci9re9a 46 11 and and CC cord-333696-3ci9re9a 46 12 functionally functionally RB cord-333696-3ci9re9a 46 13 interacts interact VBZ cord-333696-3ci9re9a 46 14 with with IN cord-333696-3ci9re9a 46 15 nAChRs nachr NNS cord-333696-3ci9re9a 46 16 [ [ -LRB- cord-333696-3ci9re9a 46 17 29 29 CD cord-333696-3ci9re9a 46 18 , , , cord-333696-3ci9re9a 46 19 30 30 CD cord-333696-3ci9re9a 46 20 ] ] -RRB- cord-333696-3ci9re9a 46 21 . . . cord-333696-3ci9re9a 47 1 They -PRON- PRP cord-333696-3ci9re9a 47 2 considered consider VBD cord-333696-3ci9re9a 47 3 neural neural JJ cord-333696-3ci9re9a 47 4 cells cell NNS cord-333696-3ci9re9a 47 5 and and CC cord-333696-3ci9re9a 47 6 astrocytes astrocyte NNS cord-333696-3ci9re9a 47 7 ( ( -LRB- cord-333696-3ci9re9a 47 8 especially especially RB cord-333696-3ci9re9a 47 9 in in IN cord-333696-3ci9re9a 47 10 the the DT cord-333696-3ci9re9a 47 11 hypothalamus hypothalamus NN cord-333696-3ci9re9a 47 12 and and CC cord-333696-3ci9re9a 47 13 brain brain NN cord-333696-3ci9re9a 47 14 stem stem NN cord-333696-3ci9re9a 47 15 ) ) -RRB- cord-333696-3ci9re9a 47 16 more more RBR cord-333696-3ci9re9a 47 17 prone prone JJ cord-333696-3ci9re9a 47 18 to to IN cord-333696-3ci9re9a 47 19 infection infection NN cord-333696-3ci9re9a 47 20 in in IN cord-333696-3ci9re9a 47 21 smokers smoker NNS cord-333696-3ci9re9a 47 22 because because IN cord-333696-3ci9re9a 47 23 nicotine nicotine NN cord-333696-3ci9re9a 47 24 stimulation stimulation NN cord-333696-3ci9re9a 47 25 of of IN cord-333696-3ci9re9a 47 26 the the DT cord-333696-3ci9re9a 47 27 nAChR nAChR NNP cord-333696-3ci9re9a 47 28 was be VBD cord-333696-3ci9re9a 47 29 found find VBN cord-333696-3ci9re9a 47 30 to to TO cord-333696-3ci9re9a 47 31 increase increase VB cord-333696-3ci9re9a 47 32 ACE2 ACE2 NNP cord-333696-3ci9re9a 47 33 expression expression NN cord-333696-3ci9re9a 47 34 within within IN cord-333696-3ci9re9a 47 35 them -PRON- PRP cord-333696-3ci9re9a 47 36 ( ( -LRB- cord-333696-3ci9re9a 47 37 Figure figure NN cord-333696-3ci9re9a 47 38 3 3 CD cord-333696-3ci9re9a 47 39 ) ) -RRB- cord-333696-3ci9re9a 48 1 [ [ -LRB- cord-333696-3ci9re9a 48 2 28 28 CD cord-333696-3ci9re9a 48 3 ] ] -RRB- cord-333696-3ci9re9a 48 4 [ [ -LRB- cord-333696-3ci9re9a 48 5 29 29 CD cord-333696-3ci9re9a 48 6 ] ] -RRB- cord-333696-3ci9re9a 48 7 [ [ -LRB- cord-333696-3ci9re9a 48 8 30 30 CD cord-333696-3ci9re9a 48 9 ] ] -RRB- cord-333696-3ci9re9a 48 10 . . . cord-333696-3ci9re9a 49 1 ACE2 ACE2 NNP cord-333696-3ci9re9a 49 2 signaling signal VBG cord-333696-3ci9re9a 49 3 pathway pathway NN cord-333696-3ci9re9a 49 4 is be VBZ cord-333696-3ci9re9a 49 5 believed believe VBN cord-333696-3ci9re9a 49 6 to to TO cord-333696-3ci9re9a 49 7 counteract counteract VB cord-333696-3ci9re9a 49 8 oxidative oxidative JJ cord-333696-3ci9re9a 49 9 stress stress NN cord-333696-3ci9re9a 49 10 and and CC cord-333696-3ci9re9a 49 11 neuroinflammation neuroinflammation NN cord-333696-3ci9re9a 49 12 , , , cord-333696-3ci9re9a 49 13 thus thus RB cord-333696-3ci9re9a 49 14 , , , cord-333696-3ci9re9a 49 15 disruption disruption NN cord-333696-3ci9re9a 49 16 in in IN cord-333696-3ci9re9a 49 17 ACE ace NN cord-333696-3ci9re9a 49 18 balance balance NN cord-333696-3ci9re9a 49 19 can can MD cord-333696-3ci9re9a 49 20 lead lead VB cord-333696-3ci9re9a 49 21 to to IN cord-333696-3ci9re9a 49 22 neurodegeneration neurodegeneration NN cord-333696-3ci9re9a 49 23 of of IN cord-333696-3ci9re9a 49 24 dopaminergic dopaminergic JJ cord-333696-3ci9re9a 49 25 neurons neuron NNS cord-333696-3ci9re9a 49 26 [ [ -LRB- cord-333696-3ci9re9a 49 27 31 31 CD cord-333696-3ci9re9a 49 28 ] ] -RRB- cord-333696-3ci9re9a 49 29 or or CC cord-333696-3ci9re9a 49 30 impairment impairment NN cord-333696-3ci9re9a 49 31 in in IN cord-333696-3ci9re9a 49 32 cholinergic cholinergic JJ cord-333696-3ci9re9a 49 33 pathways pathway NNS cord-333696-3ci9re9a 49 34 which which WDT cord-333696-3ci9re9a 49 35 might may MD cord-333696-3ci9re9a 49 36 participate participate VB cord-333696-3ci9re9a 49 37 in in IN cord-333696-3ci9re9a 49 38 the the DT cord-333696-3ci9re9a 49 39 progression progression NN cord-333696-3ci9re9a 49 40 of of IN cord-333696-3ci9re9a 49 41 Alzheimer Alzheimer NNP cord-333696-3ci9re9a 49 42 's 's POS cord-333696-3ci9re9a 49 43 disease disease NN cord-333696-3ci9re9a 49 44 [ [ -LRB- cord-333696-3ci9re9a 49 45 32 32 CD cord-333696-3ci9re9a 49 46 ] ] -RRB- cord-333696-3ci9re9a 49 47 . . . cord-333696-3ci9re9a 50 1 We -PRON- PRP cord-333696-3ci9re9a 50 2 believe believe VBP cord-333696-3ci9re9a 50 3 that that IN cord-333696-3ci9re9a 50 4 this this DT cord-333696-3ci9re9a 50 5 association association NN cord-333696-3ci9re9a 50 6 between between IN cord-333696-3ci9re9a 50 7 smoking smoking NN cord-333696-3ci9re9a 50 8 and and CC cord-333696-3ci9re9a 50 9 COVID-19 covid-19 VB cord-333696-3ci9re9a 50 10 neurological neurological JJ cord-333696-3ci9re9a 50 11 manifestations manifestation NNS cord-333696-3ci9re9a 50 12 , , , cord-333696-3ci9re9a 50 13 if if IN cord-333696-3ci9re9a 50 14 proven prove VBN cord-333696-3ci9re9a 50 15 , , , cord-333696-3ci9re9a 50 16 might may MD cord-333696-3ci9re9a 50 17 be be VB cord-333696-3ci9re9a 50 18 of of IN cord-333696-3ci9re9a 50 19 great great JJ cord-333696-3ci9re9a 50 20 impact impact NN cord-333696-3ci9re9a 50 21 , , , cord-333696-3ci9re9a 50 22 since since IN cord-333696-3ci9re9a 50 23 all all PDT cord-333696-3ci9re9a 50 24 the the DT cord-333696-3ci9re9a 50 25 people people NNS cord-333696-3ci9re9a 50 26 worldwide worldwide RB cord-333696-3ci9re9a 50 27 are be VBP cord-333696-3ci9re9a 50 28 currently currently RB cord-333696-3ci9re9a 50 29 at at IN cord-333696-3ci9re9a 50 30 high high JJ cord-333696-3ci9re9a 50 31 risk risk NN cord-333696-3ci9re9a 50 32 of of IN cord-333696-3ci9re9a 50 33 being be VBG cord-333696-3ci9re9a 50 34 exposed expose VBN cord-333696-3ci9re9a 50 35 to to IN cord-333696-3ci9re9a 50 36 smoking smoking NN cord-333696-3ci9re9a 50 37 and and CC cord-333696-3ci9re9a 50 38 COVID-19 covid-19 JJ cord-333696-3ci9re9a 50 39 infection infection NN cord-333696-3ci9re9a 50 40 . . . cord-333696-3ci9re9a 51 1 Hence hence RB cord-333696-3ci9re9a 51 2 , , , cord-333696-3ci9re9a 51 3 more more JJR cord-333696-3ci9re9a 51 4 studies study NNS cord-333696-3ci9re9a 51 5 are be VBP cord-333696-3ci9re9a 51 6 strongly strongly RB cord-333696-3ci9re9a 51 7 encouraged encourage VBN cord-333696-3ci9re9a 51 8 in in IN cord-333696-3ci9re9a 51 9 this this DT cord-333696-3ci9re9a 51 10 regard regard NN cord-333696-3ci9re9a 51 11 . . . cord-333696-3ci9re9a 52 1 Data datum NNS cord-333696-3ci9re9a 52 2 on on IN cord-333696-3ci9re9a 52 3 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 52 4 is be VBZ cord-333696-3ci9re9a 52 5 not not RB cord-333696-3ci9re9a 52 6 yet yet RB cord-333696-3ci9re9a 52 7 complete complete JJ cord-333696-3ci9re9a 52 8 or or CC cord-333696-3ci9re9a 52 9 comprehensive comprehensive JJ cord-333696-3ci9re9a 52 10 as as IN cord-333696-3ci9re9a 52 11 we -PRON- PRP cord-333696-3ci9re9a 52 12 are be VBP cord-333696-3ci9re9a 52 13 still still RB cord-333696-3ci9re9a 52 14 in in IN cord-333696-3ci9re9a 52 15 the the DT cord-333696-3ci9re9a 52 16 midst midst NN cord-333696-3ci9re9a 52 17 of of IN cord-333696-3ci9re9a 52 18 the the DT cord-333696-3ci9re9a 52 19 active active JJ cord-333696-3ci9re9a 52 20 pandemic pandemic NN cord-333696-3ci9re9a 52 21 [ [ -LRB- cord-333696-3ci9re9a 52 22 33 33 CD cord-333696-3ci9re9a 52 23 ] ] -RRB- cord-333696-3ci9re9a 52 24 [ [ -LRB- cord-333696-3ci9re9a 52 25 34 34 CD cord-333696-3ci9re9a 52 26 ] ] -RRB- cord-333696-3ci9re9a 52 27 [ [ -LRB- cord-333696-3ci9re9a 52 28 35 35 CD cord-333696-3ci9re9a 52 29 ] ] -RRB- cord-333696-3ci9re9a 52 30 [ [ -LRB- cord-333696-3ci9re9a 52 31 36 36 CD cord-333696-3ci9re9a 52 32 ] ] -RRB- cord-333696-3ci9re9a 52 33 . . . cord-333696-3ci9re9a 53 1 However however RB cord-333696-3ci9re9a 53 2 , , , cord-333696-3ci9re9a 53 3 early early JJ cord-333696-3ci9re9a 53 4 research research NN cord-333696-3ci9re9a 53 5 from from IN cord-333696-3ci9re9a 53 6 Wuhan Wuhan NNP cord-333696-3ci9re9a 53 7 , , , cord-333696-3ci9re9a 53 8 China China NNP cord-333696-3ci9re9a 53 9 reported report VBD cord-333696-3ci9re9a 53 10 that that IN cord-333696-3ci9re9a 53 11 the the DT cord-333696-3ci9re9a 53 12 most most RBS cord-333696-3ci9re9a 53 13 common common JJ cord-333696-3ci9re9a 53 14 symptoms symptom NNS cord-333696-3ci9re9a 53 15 that that WDT cord-333696-3ci9re9a 53 16 appeared appear VBD cord-333696-3ci9re9a 53 17 among among IN cord-333696-3ci9re9a 53 18 patients patient NNS cord-333696-3ci9re9a 53 19 with with IN cord-333696-3ci9re9a 53 20 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 53 21 included include VBN cord-333696-3ci9re9a 53 22 fever fever NN cord-333696-3ci9re9a 53 23 ( ( -LRB- cord-333696-3ci9re9a 53 24 98.6 98.6 CD cord-333696-3ci9re9a 53 25 % % NN cord-333696-3ci9re9a 53 26 ) ) -RRB- cord-333696-3ci9re9a 53 27 , , , cord-333696-3ci9re9a 53 28 fatigue fatigue NN cord-333696-3ci9re9a 53 29 ( ( -LRB- cord-333696-3ci9re9a 53 30 69.6 69.6 CD cord-333696-3ci9re9a 53 31 % % NN cord-333696-3ci9re9a 53 32 ) ) -RRB- cord-333696-3ci9re9a 53 33 , , , cord-333696-3ci9re9a 53 34 and and CC cord-333696-3ci9re9a 53 35 a a DT cord-333696-3ci9re9a 53 36 dry dry JJ cord-333696-3ci9re9a 53 37 cough cough NN cord-333696-3ci9re9a 53 38 ( ( -LRB- cord-333696-3ci9re9a 53 39 59.4 59.4 CD cord-333696-3ci9re9a 53 40 % % NN cord-333696-3ci9re9a 53 41 ) ) -RRB- cord-333696-3ci9re9a 54 1 [ [ -LRB- cord-333696-3ci9re9a 54 2 37 37 CD cord-333696-3ci9re9a 54 3 ] ] -RRB- cord-333696-3ci9re9a 54 4 . . . cord-333696-3ci9re9a 55 1 While while IN cord-333696-3ci9re9a 55 2 these these DT cord-333696-3ci9re9a 55 3 symptoms symptom NNS cord-333696-3ci9re9a 55 4 are be VBP cord-333696-3ci9re9a 55 5 typical typical JJ cord-333696-3ci9re9a 55 6 of of IN cord-333696-3ci9re9a 55 7 respiratory respiratory JJ cord-333696-3ci9re9a 55 8 viruses virus NNS cord-333696-3ci9re9a 55 9 , , , cord-333696-3ci9re9a 55 10 other other JJ cord-333696-3ci9re9a 55 11 sources source NNS cord-333696-3ci9re9a 55 12 additionally additionally RB cord-333696-3ci9re9a 55 13 reported report VBD cord-333696-3ci9re9a 55 14 neurological neurological JJ cord-333696-3ci9re9a 55 15 symptoms symptom NNS cord-333696-3ci9re9a 55 16 and and CC cord-333696-3ci9re9a 55 17 manifestation manifestation NN cord-333696-3ci9re9a 55 18 in in IN cord-333696-3ci9re9a 55 19 up up IN cord-333696-3ci9re9a 55 20 to to TO cord-333696-3ci9re9a 55 21 36.4 36.4 CD cord-333696-3ci9re9a 55 22 % % NN cord-333696-3ci9re9a 55 23 of of IN cord-333696-3ci9re9a 55 24 814 814 CD cord-333696-3ci9re9a 55 25 retrospectively retrospectively RB cord-333696-3ci9re9a 55 26 studied study VBN cord-333696-3ci9re9a 55 27 COVID19 COVID19 NNP cord-333696-3ci9re9a 55 28 patients patient NNS cord-333696-3ci9re9a 55 29 ( ( -LRB- cord-333696-3ci9re9a 55 30 Table table NN cord-333696-3ci9re9a 55 31 1 1 CD cord-333696-3ci9re9a 55 32 ) ) -RRB- cord-333696-3ci9re9a 56 1 [ [ -LRB- cord-333696-3ci9re9a 56 2 8 8 CD cord-333696-3ci9re9a 56 3 ] ] -RRB- cord-333696-3ci9re9a 56 4 . . . cord-333696-3ci9re9a 57 1 Acute acute JJ cord-333696-3ci9re9a 57 2 transverse transverse JJ cord-333696-3ci9re9a 57 3 myelitis myelitis NN cord-333696-3ci9re9a 57 4 , , , cord-333696-3ci9re9a 57 5 also also RB cord-333696-3ci9re9a 57 6 referred refer VBD cord-333696-3ci9re9a 57 7 to to IN cord-333696-3ci9re9a 57 8 just just RB cord-333696-3ci9re9a 57 9 as as IN cord-333696-3ci9re9a 57 10 transverse transverse JJ cord-333696-3ci9re9a 57 11 myelitis myelitis NN cord-333696-3ci9re9a 57 12 ( ( -LRB- cord-333696-3ci9re9a 57 13 TM TM NNP cord-333696-3ci9re9a 57 14 ) ) -RRB- cord-333696-3ci9re9a 57 15 , , , cord-333696-3ci9re9a 57 16 is be VBZ cord-333696-3ci9re9a 57 17 a a DT cord-333696-3ci9re9a 57 18 rare rare JJ cord-333696-3ci9re9a 57 19 neurological neurological JJ cord-333696-3ci9re9a 57 20 disturbance disturbance NN cord-333696-3ci9re9a 57 21 consisting consist VBG cord-333696-3ci9re9a 57 22 of of IN cord-333696-3ci9re9a 57 23 an an DT cord-333696-3ci9re9a 57 24 inflammation inflammation NN cord-333696-3ci9re9a 57 25 of of IN cord-333696-3ci9re9a 57 26 the the DT cord-333696-3ci9re9a 57 27 spinal spinal JJ cord-333696-3ci9re9a 57 28 cord cord NN cord-333696-3ci9re9a 57 29 . . . cord-333696-3ci9re9a 58 1 Patients patient NNS cord-333696-3ci9re9a 58 2 with with IN cord-333696-3ci9re9a 58 3 TM TM NNP cord-333696-3ci9re9a 58 4 may may MD cord-333696-3ci9re9a 58 5 present present VB cord-333696-3ci9re9a 58 6 with with IN cord-333696-3ci9re9a 58 7 sensory sensory JJ cord-333696-3ci9re9a 58 8 changes change NNS cord-333696-3ci9re9a 58 9 , , , cord-333696-3ci9re9a 58 10 weakness weakness NN cord-333696-3ci9re9a 58 11 and and CC cord-333696-3ci9re9a 58 12 autonomic autonomic JJ cord-333696-3ci9re9a 58 13 dysfunctions dysfunction NNS cord-333696-3ci9re9a 58 14 [ [ -LRB- cord-333696-3ci9re9a 58 15 38 38 CD cord-333696-3ci9re9a 58 16 ] ] -RRB- cord-333696-3ci9re9a 58 17 . . . cord-333696-3ci9re9a 59 1 While while IN cord-333696-3ci9re9a 59 2 no no DT cord-333696-3ci9re9a 59 3 preceding precede VBG cord-333696-3ci9re9a 59 4 infection infection NN cord-333696-3ci9re9a 59 5 was be VBD cord-333696-3ci9re9a 59 6 found find VBN cord-333696-3ci9re9a 59 7 in in IN cord-333696-3ci9re9a 59 8 some some DT cord-333696-3ci9re9a 59 9 of of IN cord-333696-3ci9re9a 59 10 the the DT cord-333696-3ci9re9a 59 11 reported report VBN cord-333696-3ci9re9a 59 12 cases case NNS cord-333696-3ci9re9a 59 13 , , , cord-333696-3ci9re9a 59 14 transverse transverse JJ cord-333696-3ci9re9a 59 15 myelitis myelitis NNP cord-333696-3ci9re9a 59 16 is be VBZ cord-333696-3ci9re9a 59 17 usually usually RB cord-333696-3ci9re9a 59 18 associated associate VBN cord-333696-3ci9re9a 59 19 with with IN cord-333696-3ci9re9a 59 20 common common JJ cord-333696-3ci9re9a 59 21 viral viral JJ cord-333696-3ci9re9a 59 22 infections infection NNS cord-333696-3ci9re9a 59 23 such such JJ cord-333696-3ci9re9a 59 24 as as IN cord-333696-3ci9re9a 59 25 Varicella Varicella NNP cord-333696-3ci9re9a 59 26 Zoster Zoster NNP cord-333696-3ci9re9a 59 27 ( ( -LRB- cord-333696-3ci9re9a 59 28 VZV VZV NNP cord-333696-3ci9re9a 59 29 ) ) -RRB- cord-333696-3ci9re9a 59 30 , , , cord-333696-3ci9re9a 59 31 Herpes Herpes NNP cord-333696-3ci9re9a 59 32 viruses virus NNS cord-333696-3ci9re9a 59 33 ( ( -LRB- cord-333696-3ci9re9a 59 34 HSV-2 HSV-2 NNP cord-333696-3ci9re9a 59 35 and and CC cord-333696-3ci9re9a 59 36 Cytomegalovirus Cytomegalovirus NNP cord-333696-3ci9re9a 59 37 ) ) -RRB- cord-333696-3ci9re9a 59 38 and and CC cord-333696-3ci9re9a 59 39 enteroviruses enteroviruses NNP cord-333696-3ci9re9a 59 40 [ [ -LRB- cord-333696-3ci9re9a 59 41 39 39 CD cord-333696-3ci9re9a 59 42 ] ] -RRB- cord-333696-3ci9re9a 59 43 . . . cord-333696-3ci9re9a 60 1 In in IN cord-333696-3ci9re9a 60 2 February February NNP cord-333696-3ci9re9a 60 3 of of IN cord-333696-3ci9re9a 60 4 2020 2020 CD cord-333696-3ci9re9a 60 5 , , , cord-333696-3ci9re9a 60 6 in in IN cord-333696-3ci9re9a 60 7 Wuhan Wuhan NNP cord-333696-3ci9re9a 60 8 , , , cord-333696-3ci9re9a 60 9 China China NNP cord-333696-3ci9re9a 60 10 , , , cord-333696-3ci9re9a 60 11 an an DT cord-333696-3ci9re9a 60 12 elderly elderly JJ cord-333696-3ci9re9a 60 13 patient patient NN cord-333696-3ci9re9a 60 14 presented present VBN cord-333696-3ci9re9a 60 15 to to IN cord-333696-3ci9re9a 60 16 the the DT cord-333696-3ci9re9a 60 17 hospital hospital NN cord-333696-3ci9re9a 60 18 with with IN cord-333696-3ci9re9a 60 19 fever fever NN cord-333696-3ci9re9a 60 20 and and CC cord-333696-3ci9re9a 60 21 fatigue fatigue NN cord-333696-3ci9re9a 60 22 with with IN cord-333696-3ci9re9a 60 23 no no DT cord-333696-3ci9re9a 60 24 previous previous JJ cord-333696-3ci9re9a 60 25 contact contact NN cord-333696-3ci9re9a 60 26 with with IN cord-333696-3ci9re9a 60 27 COVID-19 covid-19 JJ cord-333696-3ci9re9a 60 28 patients patient NNS cord-333696-3ci9re9a 60 29 [ [ -LRB- cord-333696-3ci9re9a 60 30 40 40 CD cord-333696-3ci9re9a 60 31 ] ] -RRB- cord-333696-3ci9re9a 60 32 . . . cord-333696-3ci9re9a 61 1 He -PRON- PRP cord-333696-3ci9re9a 61 2 was be VBD cord-333696-3ci9re9a 61 3 found find VBN cord-333696-3ci9re9a 61 4 to to TO cord-333696-3ci9re9a 61 5 have have VB cord-333696-3ci9re9a 61 6 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 61 7 based base VBN cord-333696-3ci9re9a 61 8 on on IN cord-333696-3ci9re9a 61 9 PCR PCR NNP cord-333696-3ci9re9a 61 10 tests test NNS cord-333696-3ci9re9a 61 11 of of IN cord-333696-3ci9re9a 61 12 his -PRON- PRP$ cord-333696-3ci9re9a 61 13 nasopharyngeal nasopharyngeal JJ cord-333696-3ci9re9a 61 14 secretions secretion NNS cord-333696-3ci9re9a 61 15 . . . cord-333696-3ci9re9a 62 1 After after IN cord-333696-3ci9re9a 62 2 a a DT cord-333696-3ci9re9a 62 3 week week NN cord-333696-3ci9re9a 62 4 of of IN cord-333696-3ci9re9a 62 5 J J NNP cord-333696-3ci9re9a 62 6 o o NNP cord-333696-3ci9re9a 62 7 u u NN cord-333696-3ci9re9a 62 8 r r NNP cord-333696-3ci9re9a 62 9 n n NN cord-333696-3ci9re9a 62 10 a a DT cord-333696-3ci9re9a 62 11 l l NN cord-333696-3ci9re9a 62 12 P p NN cord-333696-3ci9re9a 62 13 r r NN cord-333696-3ci9re9a 62 14 e e NN cord-333696-3ci9re9a 63 1 -p -p : cord-333696-3ci9re9a 64 1 r r NN cord-333696-3ci9re9a 64 2 o o NN cord-333696-3ci9re9a 64 3 o o NN cord-333696-3ci9re9a 64 4 f f NN cord-333696-3ci9re9a 64 5 hospitalization hospitalization NN cord-333696-3ci9re9a 64 6 , , , cord-333696-3ci9re9a 64 7 he -PRON- PRP cord-333696-3ci9re9a 64 8 developed develop VBD cord-333696-3ci9re9a 64 9 lower low JJR cord-333696-3ci9re9a 64 10 extremity extremity NN cord-333696-3ci9re9a 64 11 weakness weakness NN cord-333696-3ci9re9a 64 12 and and CC cord-333696-3ci9re9a 64 13 paresthesia paresthesia NNS cord-333696-3ci9re9a 64 14 progressing progress VBG cord-333696-3ci9re9a 64 15 to to IN cord-333696-3ci9re9a 64 16 paralysis paralysis NN cord-333696-3ci9re9a 64 17 , , , cord-333696-3ci9re9a 64 18 along along IN cord-333696-3ci9re9a 64 19 with with IN cord-333696-3ci9re9a 64 20 urinary urinary JJ cord-333696-3ci9re9a 64 21 and and CC cord-333696-3ci9re9a 64 22 bowel bowel NN cord-333696-3ci9re9a 64 23 incontinence incontinence NN cord-333696-3ci9re9a 64 24 . . . cord-333696-3ci9re9a 65 1 He -PRON- PRP cord-333696-3ci9re9a 65 2 was be VBD cord-333696-3ci9re9a 65 3 diagnosed diagnose VBN cord-333696-3ci9re9a 65 4 with with IN cord-333696-3ci9re9a 65 5 post post JJ cord-333696-3ci9re9a 65 6 - - JJ cord-333696-3ci9re9a 65 7 infectious infectious JJ cord-333696-3ci9re9a 65 8 acute acute JJ cord-333696-3ci9re9a 65 9 transverse transverse JJ cord-333696-3ci9re9a 65 10 myelitis myelitis NN cord-333696-3ci9re9a 65 11 . . . cord-333696-3ci9re9a 66 1 IgM IgM NNP cord-333696-3ci9re9a 66 2 antibodies antibody NNS cord-333696-3ci9re9a 66 3 of of IN cord-333696-3ci9re9a 66 4 the the DT cord-333696-3ci9re9a 66 5 most most RBS cord-333696-3ci9re9a 66 6 common common JJ cord-333696-3ci9re9a 66 7 infectious infectious JJ cord-333696-3ci9re9a 66 8 organisms organism NNS cord-333696-3ci9re9a 66 9 associated associate VBN cord-333696-3ci9re9a 66 10 with with IN cord-333696-3ci9re9a 66 11 TM TM NNP cord-333696-3ci9re9a 66 12 ( ( -LRB- cord-333696-3ci9re9a 66 13 Mycoplasma mycoplasma NN cord-333696-3ci9re9a 66 14 pneumoniae pneumoniae NN cord-333696-3ci9re9a 66 15 , , , cord-333696-3ci9re9a 66 16 Ebstein Ebstein NNP cord-333696-3ci9re9a 66 17 - - HYPH cord-333696-3ci9re9a 66 18 Barr Barr NNP cord-333696-3ci9re9a 66 19 Virus Virus NNP cord-333696-3ci9re9a 66 20 , , , cord-333696-3ci9re9a 66 21 and and CC cord-333696-3ci9re9a 66 22 Cytomegalovirus Cytomegalovirus NNP cord-333696-3ci9re9a 66 23 ) ) -RRB- cord-333696-3ci9re9a 66 24 were be VBD cord-333696-3ci9re9a 66 25 negative negative JJ cord-333696-3ci9re9a 66 26 , , , cord-333696-3ci9re9a 66 27 and and CC cord-333696-3ci9re9a 66 28 it -PRON- PRP cord-333696-3ci9re9a 66 29 was be VBD cord-333696-3ci9re9a 66 30 concluded conclude VBN cord-333696-3ci9re9a 66 31 that that IN cord-333696-3ci9re9a 66 32 the the DT cord-333696-3ci9re9a 66 33 cause cause NN cord-333696-3ci9re9a 66 34 of of IN cord-333696-3ci9re9a 66 35 his -PRON- PRP$ cord-333696-3ci9re9a 66 36 post post JJ cord-333696-3ci9re9a 66 37 - - JJ cord-333696-3ci9re9a 66 38 infectious infectious JJ cord-333696-3ci9re9a 66 39 TM TM NNP cord-333696-3ci9re9a 66 40 was be VBD cord-333696-3ci9re9a 66 41 SARS SARS NNP cord-333696-3ci9re9a 66 42 - - HYPH cord-333696-3ci9re9a 66 43 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 66 44 virus virus NN cord-333696-3ci9re9a 66 45 . . . cord-333696-3ci9re9a 67 1 Although although IN cord-333696-3ci9re9a 67 2 this this DT cord-333696-3ci9re9a 67 3 case case NN cord-333696-3ci9re9a 67 4 report report NN cord-333696-3ci9re9a 67 5 provides provide VBZ cord-333696-3ci9re9a 67 6 a a DT cord-333696-3ci9re9a 67 7 strong strong JJ cord-333696-3ci9re9a 67 8 basis basis NN cord-333696-3ci9re9a 67 9 for for IN cord-333696-3ci9re9a 67 10 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 67 11 associated associate VBN cord-333696-3ci9re9a 67 12 transverse transverse NNP cord-333696-3ci9re9a 67 13 myelitis myelitis NNP cord-333696-3ci9re9a 67 14 , , , cord-333696-3ci9re9a 67 15 it -PRON- PRP cord-333696-3ci9re9a 67 16 is be VBZ cord-333696-3ci9re9a 67 17 worth worth JJ cord-333696-3ci9re9a 67 18 noting note VBG cord-333696-3ci9re9a 67 19 that that IN cord-333696-3ci9re9a 67 20 CSF CSF NNP cord-333696-3ci9re9a 67 21 serological serological JJ cord-333696-3ci9re9a 67 22 tests test NNS cord-333696-3ci9re9a 67 23 and and CC cord-333696-3ci9re9a 67 24 a a DT cord-333696-3ci9re9a 67 25 spinal spinal JJ cord-333696-3ci9re9a 67 26 cord cord NN cord-333696-3ci9re9a 67 27 MRI MRI NNP cord-333696-3ci9re9a 67 28 were be VBD cord-333696-3ci9re9a 67 29 not not RB cord-333696-3ci9re9a 67 30 performed perform VBN cord-333696-3ci9re9a 67 31 [ [ -LRB- cord-333696-3ci9re9a 67 32 40 40 CD cord-333696-3ci9re9a 67 33 ] ] -RRB- cord-333696-3ci9re9a 67 34 . . . cord-333696-3ci9re9a 68 1 symptoms symptom NNS cord-333696-3ci9re9a 68 2 . . . cord-333696-3ci9re9a 69 1 T2-weighted t2-weighted JJ cord-333696-3ci9re9a 69 2 MRI MRI NNP cord-333696-3ci9re9a 69 3 of of IN cord-333696-3ci9re9a 69 4 the the DT cord-333696-3ci9re9a 69 5 spine spine NN cord-333696-3ci9re9a 69 6 showed show VBD cord-333696-3ci9re9a 69 7 evidence evidence NN cord-333696-3ci9re9a 69 8 of of IN cord-333696-3ci9re9a 69 9 transverse transverse JJ cord-333696-3ci9re9a 69 10 myelitis myelitis NNP cord-333696-3ci9re9a 69 11 [ [ -LRB- cord-333696-3ci9re9a 69 12 41 41 CD cord-333696-3ci9re9a 69 13 , , , cord-333696-3ci9re9a 69 14 42 42 CD cord-333696-3ci9re9a 69 15 ] ] -RRB- cord-333696-3ci9re9a 69 16 . . . cord-333696-3ci9re9a 70 1 All all DT cord-333696-3ci9re9a 70 2 work work NN cord-333696-3ci9re9a 70 3 - - HYPH cord-333696-3ci9re9a 70 4 up up RP cord-333696-3ci9re9a 70 5 tests test NNS cord-333696-3ci9re9a 70 6 for for IN cord-333696-3ci9re9a 70 7 the the DT cord-333696-3ci9re9a 70 8 typical typical JJ cord-333696-3ci9re9a 70 9 viral viral JJ cord-333696-3ci9re9a 70 10 causes cause NNS cord-333696-3ci9re9a 70 11 of of IN cord-333696-3ci9re9a 70 12 transverse transverse JJ cord-333696-3ci9re9a 70 13 myelitis myelitis NNP cord-333696-3ci9re9a 70 14 came come VBD cord-333696-3ci9re9a 70 15 back back RB cord-333696-3ci9re9a 70 16 negative negative JJ cord-333696-3ci9re9a 70 17 . . . cord-333696-3ci9re9a 71 1 The the DT cord-333696-3ci9re9a 71 2 patient patient NN cord-333696-3ci9re9a 71 3 was be VBD cord-333696-3ci9re9a 71 4 able able JJ cord-333696-3ci9re9a 71 5 to to TO cord-333696-3ci9re9a 71 6 improve improve VB cord-333696-3ci9re9a 71 7 on on IN cord-333696-3ci9re9a 71 8 multiple multiple JJ cord-333696-3ci9re9a 71 9 empiric empiric JJ cord-333696-3ci9re9a 71 10 treatments treatment NNS cord-333696-3ci9re9a 71 11 , , , cord-333696-3ci9re9a 71 12 such such JJ cord-333696-3ci9re9a 71 13 as as IN cord-333696-3ci9re9a 71 14 intravenous intravenous JJ cord-333696-3ci9re9a 71 15 immunoglobulins immunoglobulin NNS cord-333696-3ci9re9a 71 16 , , , cord-333696-3ci9re9a 71 17 steroids steroid NNS cord-333696-3ci9re9a 71 18 , , , cord-333696-3ci9re9a 71 19 and and CC cord-333696-3ci9re9a 71 20 antivirals antiviral NNS cord-333696-3ci9re9a 71 21 [ [ -LRB- cord-333696-3ci9re9a 71 22 41 41 CD cord-333696-3ci9re9a 71 23 ] ] -RRB- cord-333696-3ci9re9a 71 24 . . . cord-333696-3ci9re9a 72 1 Encephalitis encephalitis NN cord-333696-3ci9re9a 72 2 and and CC cord-333696-3ci9re9a 72 3 meningitis meningitis NN cord-333696-3ci9re9a 72 4 can can MD cord-333696-3ci9re9a 72 5 be be VB cord-333696-3ci9re9a 72 6 caused cause VBN cord-333696-3ci9re9a 72 7 by by IN cord-333696-3ci9re9a 72 8 viruses virus NNS cord-333696-3ci9re9a 72 9 like like IN cord-333696-3ci9re9a 72 10 Herpes Herpes NNP cord-333696-3ci9re9a 72 11 Simplex Simplex NNP cord-333696-3ci9re9a 72 12 Virus Virus NNP cord-333696-3ci9re9a 72 13 , , , cord-333696-3ci9re9a 72 14 Rabies Rabies NNP cord-333696-3ci9re9a 72 15 and and CC cord-333696-3ci9re9a 72 16 others other NNS cord-333696-3ci9re9a 72 17 [ [ -LRB- cord-333696-3ci9re9a 72 18 43 43 CD cord-333696-3ci9re9a 72 19 ] ] -RRB- cord-333696-3ci9re9a 72 20 . . . cord-333696-3ci9re9a 73 1 They -PRON- PRP cord-333696-3ci9re9a 73 2 can can MD cord-333696-3ci9re9a 73 3 present present VB cord-333696-3ci9re9a 73 4 with with IN cord-333696-3ci9re9a 73 5 an an DT cord-333696-3ci9re9a 73 6 acute acute JJ cord-333696-3ci9re9a 73 7 onset onset NN cord-333696-3ci9re9a 73 8 fever fever NN cord-333696-3ci9re9a 73 9 , , , cord-333696-3ci9re9a 73 10 nausea nausea NN cord-333696-3ci9re9a 73 11 and and CC cord-333696-3ci9re9a 73 12 vomiting vomit VBG cord-333696-3ci9re9a 73 13 along along IN cord-333696-3ci9re9a 73 14 with with IN cord-333696-3ci9re9a 73 15 neurological neurological JJ cord-333696-3ci9re9a 73 16 manifestations manifestation NNS cord-333696-3ci9re9a 73 17 ; ; , cord-333696-3ci9re9a 73 18 including include VBG cord-333696-3ci9re9a 73 19 headache headache NN cord-333696-3ci9re9a 73 20 , , , cord-333696-3ci9re9a 73 21 altered altered JJ cord-333696-3ci9re9a 73 22 level level NN cord-333696-3ci9re9a 73 23 of of IN cord-333696-3ci9re9a 73 24 consciousness consciousness NN cord-333696-3ci9re9a 73 25 , , , cord-333696-3ci9re9a 73 26 behavioral behavioral JJ cord-333696-3ci9re9a 73 27 disturbances disturbance NNS cord-333696-3ci9re9a 73 28 , , , cord-333696-3ci9re9a 73 29 seizures seizure NNS cord-333696-3ci9re9a 73 30 , , , cord-333696-3ci9re9a 73 31 photophobia photophobia NN cord-333696-3ci9re9a 73 32 , , , cord-333696-3ci9re9a 73 33 or or CC cord-333696-3ci9re9a 73 34 hemiparesis hemiparesis NNP cord-333696-3ci9re9a 73 35 [ [ -LRB- cord-333696-3ci9re9a 73 36 43 43 CD cord-333696-3ci9re9a 73 37 , , , cord-333696-3ci9re9a 73 38 44 44 CD cord-333696-3ci9re9a 73 39 ] ] -RRB- cord-333696-3ci9re9a 73 40 . . . cord-333696-3ci9re9a 74 1 While while IN cord-333696-3ci9re9a 74 2 treatable treatable JJ cord-333696-3ci9re9a 74 3 in in IN cord-333696-3ci9re9a 74 4 most most JJS cord-333696-3ci9re9a 74 5 cases case NNS cord-333696-3ci9re9a 74 6 , , , cord-333696-3ci9re9a 74 7 early early JJ cord-333696-3ci9re9a 74 8 detection detection NN cord-333696-3ci9re9a 74 9 and and CC cord-333696-3ci9re9a 74 10 appropriate appropriate JJ cord-333696-3ci9re9a 74 11 treatment treatment NN cord-333696-3ci9re9a 74 12 are be VBP cord-333696-3ci9re9a 74 13 important important JJ cord-333696-3ci9re9a 74 14 to to TO cord-333696-3ci9re9a 74 15 avoid avoid VB cord-333696-3ci9re9a 74 16 the the DT cord-333696-3ci9re9a 74 17 development development NN cord-333696-3ci9re9a 74 18 of of IN cord-333696-3ci9re9a 74 19 long long JJ cord-333696-3ci9re9a 74 20 - - HYPH cord-333696-3ci9re9a 74 21 term term NN cord-333696-3ci9re9a 74 22 and and CC cord-333696-3ci9re9a 74 23 more more RBR cord-333696-3ci9re9a 74 24 severe severe JJ cord-333696-3ci9re9a 74 25 complications complication NNS cord-333696-3ci9re9a 74 26 . . . cord-333696-3ci9re9a 75 1 If if IN cord-333696-3ci9re9a 75 2 left left JJ cord-333696-3ci9re9a 75 3 untreated untreated JJ cord-333696-3ci9re9a 75 4 , , , cord-333696-3ci9re9a 75 5 mortality mortality NN cord-333696-3ci9re9a 75 6 rates rate NNS cord-333696-3ci9re9a 75 7 can can MD cord-333696-3ci9re9a 75 8 reach reach VB cord-333696-3ci9re9a 75 9 up up IN cord-333696-3ci9re9a 75 10 to to TO cord-333696-3ci9re9a 75 11 70 70 CD cord-333696-3ci9re9a 75 12 % % NN cord-333696-3ci9re9a 75 13 as as IN cord-333696-3ci9re9a 75 14 reported report VBN cord-333696-3ci9re9a 75 15 in in IN cord-333696-3ci9re9a 75 16 certain certain JJ cord-333696-3ci9re9a 75 17 cases case NNS cord-333696-3ci9re9a 75 18 of of IN cord-333696-3ci9re9a 75 19 herpes herpe NNS cord-333696-3ci9re9a 75 20 related relate VBN cord-333696-3ci9re9a 75 21 encephalitis encephalitis NN cord-333696-3ci9re9a 75 22 and and CC cord-333696-3ci9re9a 75 23 meningitis meningitis NN cord-333696-3ci9re9a 75 24 [ [ -LRB- cord-333696-3ci9re9a 75 25 45 45 CD cord-333696-3ci9re9a 75 26 ] ] -RRB- cord-333696-3ci9re9a 75 27 . . . cord-333696-3ci9re9a 76 1 Recently recently RB cord-333696-3ci9re9a 76 2 , , , cord-333696-3ci9re9a 76 3 during during IN cord-333696-3ci9re9a 76 4 the the DT cord-333696-3ci9re9a 76 5 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 76 6 pandemic pandemic NN cord-333696-3ci9re9a 76 7 , , , cord-333696-3ci9re9a 76 8 a a DT cord-333696-3ci9re9a 76 9 24-year 24-year JJ cord-333696-3ci9re9a 76 10 - - HYPH cord-333696-3ci9re9a 76 11 old old JJ cord-333696-3ci9re9a 76 12 man man NN cord-333696-3ci9re9a 76 13 was be VBD cord-333696-3ci9re9a 76 14 transferred transfer VBN cord-333696-3ci9re9a 76 15 to to IN cord-333696-3ci9re9a 76 16 the the DT cord-333696-3ci9re9a 76 17 University University NNP cord-333696-3ci9re9a 76 18 of of IN cord-333696-3ci9re9a 76 19 Yamanashi Yamanashi NNP cord-333696-3ci9re9a 76 20 Hospital Hospital NNP cord-333696-3ci9re9a 76 21 in in IN cord-333696-3ci9re9a 76 22 Japan Japan NNP cord-333696-3ci9re9a 76 23 after after IN cord-333696-3ci9re9a 76 24 being be VBG cord-333696-3ci9re9a 76 25 found find VBN cord-333696-3ci9re9a 76 26 unconscious unconscious JJ cord-333696-3ci9re9a 76 27 in in IN cord-333696-3ci9re9a 76 28 his -PRON- PRP$ cord-333696-3ci9re9a 76 29 home home NN cord-333696-3ci9re9a 76 30 [ [ -LRB- cord-333696-3ci9re9a 76 31 46 46 CD cord-333696-3ci9re9a 76 32 ] ] -RRB- cord-333696-3ci9re9a 76 33 . . . cord-333696-3ci9re9a 77 1 He -PRON- PRP cord-333696-3ci9re9a 77 2 reported report VBD cord-333696-3ci9re9a 77 3 typical typical JJ cord-333696-3ci9re9a 77 4 signs sign NNS cord-333696-3ci9re9a 77 5 of of IN cord-333696-3ci9re9a 77 6 meningitis meningitis NN cord-333696-3ci9re9a 77 7 and and CC cord-333696-3ci9re9a 77 8 encephalitis encephalitis NN cord-333696-3ci9re9a 77 9 . . . cord-333696-3ci9re9a 78 1 CSF CSF NNP cord-333696-3ci9re9a 78 2 was be VBD cord-333696-3ci9re9a 78 3 found find VBN cord-333696-3ci9re9a 78 4 to to TO cord-333696-3ci9re9a 78 5 be be VB cord-333696-3ci9re9a 78 6 positive positive JJ cord-333696-3ci9re9a 78 7 for for IN cord-333696-3ci9re9a 78 8 SARS SARS NNP cord-333696-3ci9re9a 78 9 - - HYPH cord-333696-3ci9re9a 78 10 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 78 11 , , , cord-333696-3ci9re9a 78 12 while while IN cord-333696-3ci9re9a 78 13 his -PRON- PRP$ cord-333696-3ci9re9a 78 14 nasopharyngeal nasopharyngeal JJ cord-333696-3ci9re9a 78 15 secretions secretion NNS cord-333696-3ci9re9a 78 16 were be VBD cord-333696-3ci9re9a 78 17 negative negative JJ cord-333696-3ci9re9a 78 18 . . . cord-333696-3ci9re9a 79 1 This this DT cord-333696-3ci9re9a 79 2 case case NN cord-333696-3ci9re9a 79 3 provides provide VBZ cord-333696-3ci9re9a 79 4 evidence evidence NN cord-333696-3ci9re9a 79 5 of of IN cord-333696-3ci9re9a 79 6 the the DT cord-333696-3ci9re9a 79 7 neuroinvasive neuroinvasive JJ cord-333696-3ci9re9a 79 8 potential potential NN cord-333696-3ci9re9a 79 9 of of IN cord-333696-3ci9re9a 79 10 SARS SARS NNP cord-333696-3ci9re9a 79 11 - - HYPH cord-333696-3ci9re9a 79 12 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 79 13 and and CC cord-333696-3ci9re9a 79 14 its -PRON- PRP$ cord-333696-3ci9re9a 79 15 role role NN cord-333696-3ci9re9a 79 16 in in IN cord-333696-3ci9re9a 79 17 the the DT cord-333696-3ci9re9a 79 18 development development NN cord-333696-3ci9re9a 79 19 of of IN cord-333696-3ci9re9a 79 20 meningitis meningitis NN cord-333696-3ci9re9a 79 21 / / , cord-333696-3ci9re9a 79 22 encephalitis encephalitis RB cord-333696-3ci9re9a 79 23 . . . cord-333696-3ci9re9a 80 1 Besides besides RB cord-333696-3ci9re9a 80 2 , , , cord-333696-3ci9re9a 80 3 it -PRON- PRP cord-333696-3ci9re9a 80 4 also also RB cord-333696-3ci9re9a 80 5 raises raise VBZ cord-333696-3ci9re9a 80 6 the the DT cord-333696-3ci9re9a 80 7 concern concern NN cord-333696-3ci9re9a 80 8 of of IN cord-333696-3ci9re9a 80 9 having have VBG cord-333696-3ci9re9a 80 10 patients patient NNS cord-333696-3ci9re9a 80 11 with with IN cord-333696-3ci9re9a 80 12 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 80 13 that that WDT cord-333696-3ci9re9a 80 14 have have VBP cord-333696-3ci9re9a 80 15 negative negative JJ cord-333696-3ci9re9a 80 16 nasopharyngeal nasopharyngeal JJ cord-333696-3ci9re9a 80 17 swabs swab NNS cord-333696-3ci9re9a 80 18 for for IN cord-333696-3ci9re9a 80 19 the the DT cord-333696-3ci9re9a 80 20 virus virus NN cord-333696-3ci9re9a 80 21 . . . cord-333696-3ci9re9a 81 1 Another another DT cord-333696-3ci9re9a 81 2 case case NN cord-333696-3ci9re9a 81 3 of of IN cord-333696-3ci9re9a 81 4 COVID-19-associated COVID-19-associated NNP cord-333696-3ci9re9a 81 5 encephalitis encephalitis NNP cord-333696-3ci9re9a 81 6 was be VBD cord-333696-3ci9re9a 81 7 reported report VBN cord-333696-3ci9re9a 81 8 by by IN cord-333696-3ci9re9a 81 9 Efe Efe NNP cord-333696-3ci9re9a 81 10 et et NNP cord-333696-3ci9re9a 81 11 al al NNP cord-333696-3ci9re9a 81 12 . . . cord-333696-3ci9re9a 82 1 ( ( -LRB- cord-333696-3ci9re9a 82 2 2020 2020 CD cord-333696-3ci9re9a 82 3 ) ) -RRB- cord-333696-3ci9re9a 82 4 in in IN cord-333696-3ci9re9a 82 5 Turkey Turkey NNP cord-333696-3ci9re9a 82 6 [ [ -LRB- cord-333696-3ci9re9a 82 7 47 47 CD cord-333696-3ci9re9a 82 8 ] ] -RRB- cord-333696-3ci9re9a 82 9 . . . cord-333696-3ci9re9a 83 1 A a DT cord-333696-3ci9re9a 83 2 35-year 35-year JJ cord-333696-3ci9re9a 83 3 - - HYPH cord-333696-3ci9re9a 83 4 old old JJ cord-333696-3ci9re9a 83 5 female female JJ cord-333696-3ci9re9a 83 6 patient patient NN cord-333696-3ci9re9a 83 7 was be VBD cord-333696-3ci9re9a 83 8 found find VBN cord-333696-3ci9re9a 83 9 to to TO cord-333696-3ci9re9a 83 10 be be VB cord-333696-3ci9re9a 83 11 positive positive JJ cord-333696-3ci9re9a 83 12 for for IN cord-333696-3ci9re9a 83 13 SARS SARS NNP cord-333696-3ci9re9a 83 14 - - HYPH cord-333696-3ci9re9a 83 15 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 83 16 after after IN cord-333696-3ci9re9a 83 17 J J NNP cord-333696-3ci9re9a 83 18 o o NN cord-333696-3ci9re9a 83 19 u u NN cord-333696-3ci9re9a 83 20 r r NN cord-333696-3ci9re9a 83 21 n n NN cord-333696-3ci9re9a 83 22 a a DT cord-333696-3ci9re9a 83 23 l l NN cord-333696-3ci9re9a 83 24 P p NN cord-333696-3ci9re9a 83 25 r r NN cord-333696-3ci9re9a 83 26 e e NN cord-333696-3ci9re9a 83 27 -p -p NN cord-333696-3ci9re9a 84 1 r r LS cord-333696-3ci9re9a 85 1 o o UH cord-333696-3ci9re9a 85 2 o o NN cord-333696-3ci9re9a 85 3 f f XX cord-333696-3ci9re9a 85 4 undergoing undergo VBG cord-333696-3ci9re9a 85 5 a a DT cord-333696-3ci9re9a 85 6 left left JJ cord-333696-3ci9re9a 85 7 anterior anterior JJ cord-333696-3ci9re9a 85 8 temporal temporal JJ cord-333696-3ci9re9a 85 9 lobectomy lobectomy NN cord-333696-3ci9re9a 85 10 for for IN cord-333696-3ci9re9a 85 11 refractory refractory JJ cord-333696-3ci9re9a 85 12 seizures seizure NNS cord-333696-3ci9re9a 85 13 [ [ -LRB- cord-333696-3ci9re9a 85 14 47 47 CD cord-333696-3ci9re9a 85 15 ] ] -RRB- cord-333696-3ci9re9a 85 16 . . . cord-333696-3ci9re9a 86 1 This this DT cord-333696-3ci9re9a 86 2 patient patient NN cord-333696-3ci9re9a 86 3 's 's POS cord-333696-3ci9re9a 86 4 preoperative preoperative JJ cord-333696-3ci9re9a 86 5 magnetic magnetic JJ cord-333696-3ci9re9a 86 6 resonance resonance NN cord-333696-3ci9re9a 86 7 imaging imaging NN cord-333696-3ci9re9a 86 8 ( ( -LRB- cord-333696-3ci9re9a 86 9 MRI MRI NNP cord-333696-3ci9re9a 86 10 ) ) -RRB- cord-333696-3ci9re9a 86 11 and and CC cord-333696-3ci9re9a 86 12 magnetic magnetic JJ cord-333696-3ci9re9a 86 13 resonance resonance NN cord-333696-3ci9re9a 86 14 spectroscopy spectroscopy NN cord-333696-3ci9re9a 86 15 ( ( -LRB- cord-333696-3ci9re9a 86 16 MRS MRS NNP cord-333696-3ci9re9a 86 17 ) ) -RRB- cord-333696-3ci9re9a 86 18 result result NN cord-333696-3ci9re9a 86 19 were be VBD cord-333696-3ci9re9a 86 20 suggestive suggestive JJ cord-333696-3ci9re9a 86 21 of of IN cord-333696-3ci9re9a 86 22 high high JJ cord-333696-3ci9re9a 86 23 - - HYPH cord-333696-3ci9re9a 86 24 grade grade NN cord-333696-3ci9re9a 86 25 glioma glioma NN cord-333696-3ci9re9a 86 26 , , , cord-333696-3ci9re9a 86 27 however however RB cord-333696-3ci9re9a 86 28 , , , cord-333696-3ci9re9a 86 29 a a DT cord-333696-3ci9re9a 86 30 biopsy biopsy NN cord-333696-3ci9re9a 86 31 taken take VBN cord-333696-3ci9re9a 86 32 during during IN cord-333696-3ci9re9a 86 33 her -PRON- PRP$ cord-333696-3ci9re9a 86 34 surgery surgery NN cord-333696-3ci9re9a 86 35 was be VBD cord-333696-3ci9re9a 86 36 nondiagnostic nondiagnostic JJ cord-333696-3ci9re9a 86 37 . . . cord-333696-3ci9re9a 87 1 Knowing know VBG cord-333696-3ci9re9a 87 2 that that IN cord-333696-3ci9re9a 87 3 encephalitis encephalitis NN cord-333696-3ci9re9a 87 4 may may MD cord-333696-3ci9re9a 87 5 often often RB cord-333696-3ci9re9a 87 6 be be VB cord-333696-3ci9re9a 87 7 indistinguishable indistinguishable JJ cord-333696-3ci9re9a 87 8 from from IN cord-333696-3ci9re9a 87 9 other other JJ cord-333696-3ci9re9a 87 10 CNS CNS NNP cord-333696-3ci9re9a 87 11 pathology pathology NN cord-333696-3ci9re9a 87 12 on on IN cord-333696-3ci9re9a 87 13 MRS MRS NNP cord-333696-3ci9re9a 87 14 [ [ -LRB- cord-333696-3ci9re9a 87 15 48 48 CD cord-333696-3ci9re9a 87 16 ] ] -RRB- cord-333696-3ci9re9a 87 17 , , , cord-333696-3ci9re9a 87 18 Efe Efe NNP cord-333696-3ci9re9a 87 19 et et NNP cord-333696-3ci9re9a 87 20 al al NNP cord-333696-3ci9re9a 87 21 . . . cord-333696-3ci9re9a 88 1 thus thus RB cord-333696-3ci9re9a 88 2 reported report VBD cord-333696-3ci9re9a 88 3 that that IN cord-333696-3ci9re9a 88 4 their -PRON- PRP$ cord-333696-3ci9re9a 88 5 patient patient NN cord-333696-3ci9re9a 88 6 could could MD cord-333696-3ci9re9a 88 7 have have VB cord-333696-3ci9re9a 88 8 a a DT cord-333696-3ci9re9a 88 9 case case NN cord-333696-3ci9re9a 88 10 of of IN cord-333696-3ci9re9a 88 11 COVID-19-associated COVID-19-associated NNP cord-333696-3ci9re9a 88 12 encephalitis encephalitis RB cord-333696-3ci9re9a 88 13 mimicking mimic VBG cord-333696-3ci9re9a 88 14 a a DT cord-333696-3ci9re9a 88 15 glioma glioma NN cord-333696-3ci9re9a 88 16 [ [ -LRB- cord-333696-3ci9re9a 88 17 47 47 CD cord-333696-3ci9re9a 88 18 ] ] -RRB- cord-333696-3ci9re9a 88 19 . . . cord-333696-3ci9re9a 89 1 Moreover moreover RB cord-333696-3ci9re9a 89 2 , , , cord-333696-3ci9re9a 89 3 Mild Mild NNP cord-333696-3ci9re9a 89 4 encephalitis encephalitis NN cord-333696-3ci9re9a 89 5 / / , cord-333696-3ci9re9a 89 6 encephalopathy encephalopathy NN cord-333696-3ci9re9a 89 7 with with IN cord-333696-3ci9re9a 89 8 a a DT cord-333696-3ci9re9a 89 9 reversible reversible JJ cord-333696-3ci9re9a 89 10 splenial splenial JJ cord-333696-3ci9re9a 89 11 lesion lesion NN cord-333696-3ci9re9a 89 12 ( ( -LRB- cord-333696-3ci9re9a 89 13 MERS MERS NNP cord-333696-3ci9re9a 89 14 ) ) -RRB- cord-333696-3ci9re9a 89 15 was be VBD cord-333696-3ci9re9a 89 16 reported report VBN cord-333696-3ci9re9a 89 17 in in IN cord-333696-3ci9re9a 89 18 a a DT cord-333696-3ci9re9a 89 19 COVID-19 covid-19 JJ cord-333696-3ci9re9a 89 20 patient patient NN cord-333696-3ci9re9a 89 21 [ [ -LRB- cord-333696-3ci9re9a 89 22 49 49 CD cord-333696-3ci9re9a 89 23 ] ] -RRB- cord-333696-3ci9re9a 89 24 . . . cord-333696-3ci9re9a 90 1 MERS MERS NNP cord-333696-3ci9re9a 90 2 is be VBZ cord-333696-3ci9re9a 90 3 an an DT cord-333696-3ci9re9a 90 4 encephalitis encephalitis RB cord-333696-3ci9re9a 90 5 / / SYM cord-333696-3ci9re9a 90 6 encephalopathy encephalopathy NN cord-333696-3ci9re9a 90 7 syndrome syndrome NN cord-333696-3ci9re9a 90 8 that that WDT cord-333696-3ci9re9a 90 9 is be VBZ cord-333696-3ci9re9a 90 10 associated associate VBN cord-333696-3ci9re9a 90 11 with with IN cord-333696-3ci9re9a 90 12 viral viral JJ cord-333696-3ci9re9a 90 13 infections infection NNS cord-333696-3ci9re9a 90 14 [ [ -LRB- cord-333696-3ci9re9a 90 15 50 50 CD cord-333696-3ci9re9a 90 16 , , , cord-333696-3ci9re9a 90 17 51 51 CD cord-333696-3ci9re9a 90 18 ] ] -RRB- cord-333696-3ci9re9a 90 19 . . . cord-333696-3ci9re9a 91 1 This this DT cord-333696-3ci9re9a 91 2 was be VBD cord-333696-3ci9re9a 91 3 the the DT cord-333696-3ci9re9a 91 4 first first JJ cord-333696-3ci9re9a 91 5 reported report VBN cord-333696-3ci9re9a 91 6 case case NN cord-333696-3ci9re9a 91 7 of of IN cord-333696-3ci9re9a 91 8 MERS MERS NNP cord-333696-3ci9re9a 91 9 associated associate VBN cord-333696-3ci9re9a 91 10 with with IN cord-333696-3ci9re9a 91 11 coronavirus coronavirus NN cord-333696-3ci9re9a 91 12 infection infection NN cord-333696-3ci9re9a 91 13 , , , cord-333696-3ci9re9a 91 14 which which WDT cord-333696-3ci9re9a 91 15 adds add VBZ cord-333696-3ci9re9a 91 16 to to IN cord-333696-3ci9re9a 91 17 the the DT cord-333696-3ci9re9a 91 18 expanding expand VBG cord-333696-3ci9re9a 91 19 list list NN cord-333696-3ci9re9a 91 20 of of IN cord-333696-3ci9re9a 91 21 differential differential JJ cord-333696-3ci9re9a 91 22 diagnoses diagnosis NNS cord-333696-3ci9re9a 91 23 to to TO cord-333696-3ci9re9a 91 24 be be VB cord-333696-3ci9re9a 91 25 considered consider VBN cord-333696-3ci9re9a 91 26 in in IN cord-333696-3ci9re9a 91 27 a a DT cord-333696-3ci9re9a 91 28 COVID-19 covid-19 JJ cord-333696-3ci9re9a 91 29 patient patient NN cord-333696-3ci9re9a 91 30 with with IN cord-333696-3ci9re9a 91 31 neurological neurological JJ cord-333696-3ci9re9a 91 32 signs sign NNS cord-333696-3ci9re9a 91 33 , , , cord-333696-3ci9re9a 91 34 most most RBS cord-333696-3ci9re9a 91 35 notably notably RB cord-333696-3ci9re9a 91 36 ; ; : cord-333696-3ci9re9a 91 37 cerebellar cerebellar JJ cord-333696-3ci9re9a 91 38 ataxia ataxia NN cord-333696-3ci9re9a 91 39 and and CC cord-333696-3ci9re9a 91 40 disturbance disturbance NN cord-333696-3ci9re9a 91 41 in in IN cord-333696-3ci9re9a 91 42 consciousness consciousness NN cord-333696-3ci9re9a 91 43 [ [ -LRB- cord-333696-3ci9re9a 91 44 49 49 CD cord-333696-3ci9re9a 91 45 , , , cord-333696-3ci9re9a 91 46 52 52 CD cord-333696-3ci9re9a 91 47 , , , cord-333696-3ci9re9a 91 48 53 53 CD cord-333696-3ci9re9a 91 49 ] ] -RRB- cord-333696-3ci9re9a 91 50 . . . cord-333696-3ci9re9a 92 1 Infectious infectious JJ cord-333696-3ci9re9a 92 2 toxic toxic JJ cord-333696-3ci9re9a 92 3 encephalopathy encephalopathy NN cord-333696-3ci9re9a 92 4 , , , cord-333696-3ci9re9a 92 5 also also RB cord-333696-3ci9re9a 92 6 known know VBN cord-333696-3ci9re9a 92 7 as as IN cord-333696-3ci9re9a 92 8 acute acute JJ cord-333696-3ci9re9a 92 9 toxic toxic JJ cord-333696-3ci9re9a 92 10 encephalitis encephalitis RB cord-333696-3ci9re9a 92 11 , , , cord-333696-3ci9re9a 92 12 is be VBZ cord-333696-3ci9re9a 92 13 a a DT cord-333696-3ci9re9a 92 14 rare rare JJ cord-333696-3ci9re9a 92 15 type type NN cord-333696-3ci9re9a 92 16 of of IN cord-333696-3ci9re9a 92 17 reversible reversible JJ cord-333696-3ci9re9a 92 18 brain brain NN cord-333696-3ci9re9a 92 19 dysfunction dysfunction NN cord-333696-3ci9re9a 92 20 syndrome syndrome NN cord-333696-3ci9re9a 92 21 associated associate VBN cord-333696-3ci9re9a 92 22 with with IN cord-333696-3ci9re9a 92 23 cerebral cerebral JJ cord-333696-3ci9re9a 92 24 edema edema NN cord-333696-3ci9re9a 92 25 , , , cord-333696-3ci9re9a 92 26 with with IN cord-333696-3ci9re9a 92 27 no no DT cord-333696-3ci9re9a 92 28 evidence evidence NN cord-333696-3ci9re9a 92 29 of of IN cord-333696-3ci9re9a 92 30 inflammation inflammation NN cord-333696-3ci9re9a 92 31 on on IN cord-333696-3ci9re9a 92 32 cerebrospinal cerebrospinal JJ cord-333696-3ci9re9a 92 33 fluid fluid NN cord-333696-3ci9re9a 92 34 analysis analysis NN cord-333696-3ci9re9a 92 35 . . . cord-333696-3ci9re9a 93 1 Metabolic metabolic JJ cord-333696-3ci9re9a 93 2 disorders disorder NNS cord-333696-3ci9re9a 93 3 , , , cord-333696-3ci9re9a 93 4 systemic systemic JJ cord-333696-3ci9re9a 93 5 toxemia toxemia NN cord-333696-3ci9re9a 93 6 , , , cord-333696-3ci9re9a 93 7 and and CC cord-333696-3ci9re9a 93 8 hypoxia hypoxia NN cord-333696-3ci9re9a 93 9 are be VBP cord-333696-3ci9re9a 93 10 considered consider VBN cord-333696-3ci9re9a 93 11 contributing contribute VBG cord-333696-3ci9re9a 93 12 factors factor NNS cord-333696-3ci9re9a 93 13 during during IN cord-333696-3ci9re9a 93 14 the the DT cord-333696-3ci9re9a 93 15 process process NN cord-333696-3ci9re9a 93 16 of of IN cord-333696-3ci9re9a 93 17 acute acute JJ cord-333696-3ci9re9a 93 18 infection infection NN cord-333696-3ci9re9a 93 19 [ [ -LRB- cord-333696-3ci9re9a 93 20 54 54 CD cord-333696-3ci9re9a 93 21 ] ] -RRB- cord-333696-3ci9re9a 93 22 [ [ -LRB- cord-333696-3ci9re9a 93 23 55 55 CD cord-333696-3ci9re9a 93 24 ] ] -RRB- cord-333696-3ci9re9a 93 25 [ [ -LRB- cord-333696-3ci9re9a 93 26 56 56 CD cord-333696-3ci9re9a 93 27 ] ] -RRB- cord-333696-3ci9re9a 93 28 . . . cord-333696-3ci9re9a 94 1 It -PRON- PRP cord-333696-3ci9re9a 94 2 has have VBZ cord-333696-3ci9re9a 94 3 a a DT cord-333696-3ci9re9a 94 4 wide wide JJ cord-333696-3ci9re9a 94 5 clinical clinical JJ cord-333696-3ci9re9a 94 6 presentation presentation NN cord-333696-3ci9re9a 94 7 . . . cord-333696-3ci9re9a 95 1 Patients patient NNS cord-333696-3ci9re9a 95 2 with with IN cord-333696-3ci9re9a 95 3 a a DT cord-333696-3ci9re9a 95 4 mild mild JJ cord-333696-3ci9re9a 95 5 form form NN cord-333696-3ci9re9a 95 6 of of IN cord-333696-3ci9re9a 95 7 the the DT cord-333696-3ci9re9a 95 8 disease disease NN cord-333696-3ci9re9a 95 9 may may MD cord-333696-3ci9re9a 95 10 develop develop VB cord-333696-3ci9re9a 95 11 headache headache NN cord-333696-3ci9re9a 95 12 , , , cord-333696-3ci9re9a 95 13 dysphoria dysphoria NN cord-333696-3ci9re9a 95 14 , , , cord-333696-3ci9re9a 95 15 or or CC cord-333696-3ci9re9a 95 16 delirium delirium NN cord-333696-3ci9re9a 95 17 . . . cord-333696-3ci9re9a 96 1 While while IN cord-333696-3ci9re9a 96 2 more more RBR cord-333696-3ci9re9a 96 3 severe severe JJ cord-333696-3ci9re9a 96 4 forms form NNS cord-333696-3ci9re9a 96 5 may may MD cord-333696-3ci9re9a 96 6 lead lead VB cord-333696-3ci9re9a 96 7 to to IN cord-333696-3ci9re9a 96 8 disorientation disorientation NN cord-333696-3ci9re9a 96 9 , , , cord-333696-3ci9re9a 96 10 paralysis paralysis NN cord-333696-3ci9re9a 96 11 , , , cord-333696-3ci9re9a 96 12 loss loss NN cord-333696-3ci9re9a 96 13 of of IN cord-333696-3ci9re9a 96 14 consciousness consciousness NN cord-333696-3ci9re9a 96 15 and and CC cord-333696-3ci9re9a 96 16 even even RB cord-333696-3ci9re9a 96 17 coma coma NN cord-333696-3ci9re9a 96 18 . . . cord-333696-3ci9re9a 97 1 Acute acute JJ cord-333696-3ci9re9a 97 2 viral viral JJ cord-333696-3ci9re9a 97 3 infection infection NN cord-333696-3ci9re9a 97 4 is be VBZ cord-333696-3ci9re9a 97 5 a a DT cord-333696-3ci9re9a 97 6 known known JJ cord-333696-3ci9re9a 97 7 cause cause NN cord-333696-3ci9re9a 97 8 of of IN cord-333696-3ci9re9a 97 9 this this DT cord-333696-3ci9re9a 97 10 disease disease NN cord-333696-3ci9re9a 97 11 . . . cord-333696-3ci9re9a 98 1 COVID-19 covid-19 JJ cord-333696-3ci9re9a 98 2 infection infection NN cord-333696-3ci9re9a 98 3 has have VBZ cord-333696-3ci9re9a 98 4 been be VBN cord-333696-3ci9re9a 98 5 suggested suggest VBN cord-333696-3ci9re9a 98 6 as as IN cord-333696-3ci9re9a 98 7 a a DT cord-333696-3ci9re9a 98 8 cause cause NN cord-333696-3ci9re9a 98 9 of of IN cord-333696-3ci9re9a 98 10 this this DT cord-333696-3ci9re9a 98 11 disease disease NN cord-333696-3ci9re9a 98 12 depending depend VBG cord-333696-3ci9re9a 98 13 on on IN cord-333696-3ci9re9a 98 14 many many JJ cord-333696-3ci9re9a 98 15 findings finding NNS cord-333696-3ci9re9a 98 16 . . . cord-333696-3ci9re9a 99 1 First first RB cord-333696-3ci9re9a 99 2 , , , cord-333696-3ci9re9a 99 3 patients patient NNS cord-333696-3ci9re9a 99 4 with with IN cord-333696-3ci9re9a 99 5 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 99 6 may may MD cord-333696-3ci9re9a 99 7 suffer suffer VB cord-333696-3ci9re9a 99 8 from from IN cord-333696-3ci9re9a 99 9 severe severe JJ cord-333696-3ci9re9a 99 10 hypoxia hypoxia NN cord-333696-3ci9re9a 99 11 and and CC cord-333696-3ci9re9a 99 12 viremia viremia NN cord-333696-3ci9re9a 99 13 [ [ -LRB- cord-333696-3ci9re9a 99 14 57 57 CD cord-333696-3ci9re9a 99 15 ] ] -RRB- cord-333696-3ci9re9a 99 16 , , , cord-333696-3ci9re9a 99 17 which which WDT cord-333696-3ci9re9a 99 18 might may MD cord-333696-3ci9re9a 99 19 eventually eventually RB cord-333696-3ci9re9a 99 20 lead lead VB cord-333696-3ci9re9a 99 21 to to IN cord-333696-3ci9re9a 99 22 toxic toxic JJ cord-333696-3ci9re9a 99 23 encephalopathy encephalopathy NN cord-333696-3ci9re9a 99 24 . . . cord-333696-3ci9re9a 100 1 Moreover moreover RB cord-333696-3ci9re9a 100 2 , , , cord-333696-3ci9re9a 100 3 around around RB cord-333696-3ci9re9a 100 4 40 40 CD cord-333696-3ci9re9a 100 5 % % NN cord-333696-3ci9re9a 100 6 of of IN cord-333696-3ci9re9a 100 7 patients patient NNS cord-333696-3ci9re9a 100 8 with with IN cord-333696-3ci9re9a 100 9 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 100 10 develop develop VB cord-333696-3ci9re9a 100 11 neurological neurological JJ cord-333696-3ci9re9a 100 12 symptoms symptom NNS cord-333696-3ci9re9a 100 13 and and CC cord-333696-3ci9re9a 100 14 other other JJ cord-333696-3ci9re9a 100 15 brain brain NN cord-333696-3ci9re9a 100 16 dysfunction dysfunction NN cord-333696-3ci9re9a 100 17 symptoms symptom NNS cord-333696-3ci9re9a 100 18 [ [ -LRB- cord-333696-3ci9re9a 100 19 8 8 CD cord-333696-3ci9re9a 100 20 ] ] -RRB- cord-333696-3ci9re9a 100 21 . . . cord-333696-3ci9re9a 101 1 Added add VBN cord-333696-3ci9re9a 101 2 to to IN cord-333696-3ci9re9a 101 3 that that DT cord-333696-3ci9re9a 101 4 , , , cord-333696-3ci9re9a 101 5 brain brain NN cord-333696-3ci9re9a 101 6 edema edema NN cord-333696-3ci9re9a 101 7 has have VBZ cord-333696-3ci9re9a 101 8 been be VBN cord-333696-3ci9re9a 101 9 detected detect VBN cord-333696-3ci9re9a 101 10 in in IN cord-333696-3ci9re9a 101 11 autopsy autopsy JJ cord-333696-3ci9re9a 101 12 studies study NNS cord-333696-3ci9re9a 101 13 of of IN cord-333696-3ci9re9a 101 14 brain brain NN cord-333696-3ci9re9a 101 15 tissue tissue NN cord-333696-3ci9re9a 101 16 of of IN cord-333696-3ci9re9a 101 17 COVID-19 covid-19 CD cord-333696-3ci9re9a 101 18 patients patient NNS cord-333696-3ci9re9a 101 19 [ [ -LRB- cord-333696-3ci9re9a 101 20 58 58 CD cord-333696-3ci9re9a 101 21 ] ] -RRB- cord-333696-3ci9re9a 101 22 . . . cord-333696-3ci9re9a 102 1 Collectively collectively RB cord-333696-3ci9re9a 102 2 , , , cord-333696-3ci9re9a 102 3 these these DT cord-333696-3ci9re9a 102 4 proposals proposal NNS cord-333696-3ci9re9a 102 5 provide provide VBP cord-333696-3ci9re9a 102 6 evidence evidence NN cord-333696-3ci9re9a 102 7 that that IN cord-333696-3ci9re9a 102 8 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 102 9 could could MD cord-333696-3ci9re9a 102 10 cause cause VB cord-333696-3ci9re9a 102 11 infectious infectious JJ cord-333696-3ci9re9a 102 12 toxic toxic JJ cord-333696-3ci9re9a 102 13 encephalopathy encephalopathy NN cord-333696-3ci9re9a 102 14 , , , cord-333696-3ci9re9a 102 15 although although IN cord-333696-3ci9re9a 102 16 more more RBR cord-333696-3ci9re9a 102 17 detailed detailed JJ cord-333696-3ci9re9a 102 18 researches research NNS cord-333696-3ci9re9a 102 19 are be VBP cord-333696-3ci9re9a 102 20 still still RB cord-333696-3ci9re9a 102 21 required require VBN cord-333696-3ci9re9a 102 22 . . . cord-333696-3ci9re9a 103 1 Acute acute JJ cord-333696-3ci9re9a 103 2 Hemorrhagic Hemorrhagic NNP cord-333696-3ci9re9a 103 3 Necrotizing Necrotizing NNP cord-333696-3ci9re9a 103 4 Encephalopathy Encephalopathy NNP cord-333696-3ci9re9a 103 5 ( ( -LRB- cord-333696-3ci9re9a 103 6 ANE ANE NNP cord-333696-3ci9re9a 103 7 ) ) -RRB- cord-333696-3ci9re9a 103 8 occurs occur VBZ cord-333696-3ci9re9a 103 9 most most RBS cord-333696-3ci9re9a 103 10 commonly commonly RB cord-333696-3ci9re9a 103 11 in in IN cord-333696-3ci9re9a 103 12 the the DT cord-333696-3ci9re9a 103 13 pediatric pediatric JJ cord-333696-3ci9re9a 103 14 age age NN cord-333696-3ci9re9a 103 15 group group NN cord-333696-3ci9re9a 103 16 but but CC cord-333696-3ci9re9a 103 17 reported report VBD cord-333696-3ci9re9a 103 18 to to TO cord-333696-3ci9re9a 103 19 be be VB cord-333696-3ci9re9a 103 20 in in IN cord-333696-3ci9re9a 103 21 adults adult NNS cord-333696-3ci9re9a 103 22 as as RB cord-333696-3ci9re9a 103 23 well well RB cord-333696-3ci9re9a 103 24 . . . cord-333696-3ci9re9a 104 1 Characteristic characteristic JJ cord-333696-3ci9re9a 104 2 radiological radiological JJ cord-333696-3ci9re9a 104 3 features feature NNS cord-333696-3ci9re9a 104 4 include include VBP cord-333696-3ci9re9a 104 5 multiple multiple JJ cord-333696-3ci9re9a 104 6 symmetric symmetric JJ cord-333696-3ci9re9a 104 7 lesions lesion NNS cord-333696-3ci9re9a 104 8 with with IN cord-333696-3ci9re9a 104 9 thalamic thalamic JJ cord-333696-3ci9re9a 104 10 involvement involvement NN cord-333696-3ci9re9a 104 11 . . . cord-333696-3ci9re9a 105 1 Cerebral cerebral JJ cord-333696-3ci9re9a 105 2 white white JJ cord-333696-3ci9re9a 105 3 matter matter NN cord-333696-3ci9re9a 105 4 , , , cord-333696-3ci9re9a 105 5 brain brain NN cord-333696-3ci9re9a 105 6 stem stem NN cord-333696-3ci9re9a 105 7 , , , cord-333696-3ci9re9a 105 8 and and CC cord-333696-3ci9re9a 105 9 cerebellum cerebellum NN cord-333696-3ci9re9a 105 10 are be VBP cord-333696-3ci9re9a 105 11 other other JJ cord-333696-3ci9re9a 105 12 reported report VBN cord-333696-3ci9re9a 105 13 areas area NNS cord-333696-3ci9re9a 105 14 to to TO cord-333696-3ci9re9a 105 15 be be VB cord-333696-3ci9re9a 105 16 involved involve VBN cord-333696-3ci9re9a 105 17 [ [ -LRB- cord-333696-3ci9re9a 105 18 59 59 CD cord-333696-3ci9re9a 105 19 ] ] -RRB- cord-333696-3ci9re9a 105 20 . . . cord-333696-3ci9re9a 106 1 Acute acute JJ cord-333696-3ci9re9a 106 2 necrotizing necrotize VBG cord-333696-3ci9re9a 106 3 encephalopathy encephalopathy NN cord-333696-3ci9re9a 106 4 ( ( -LRB- cord-333696-3ci9re9a 106 5 ANE ANE NNP cord-333696-3ci9re9a 106 6 ) ) -RRB- cord-333696-3ci9re9a 106 7 is be VBZ cord-333696-3ci9re9a 106 8 a a DT cord-333696-3ci9re9a 106 9 rare rare JJ cord-333696-3ci9re9a 106 10 complication complication NN cord-333696-3ci9re9a 106 11 of of IN cord-333696-3ci9re9a 106 12 viral viral JJ cord-333696-3ci9re9a 106 13 infections infection NNS cord-333696-3ci9re9a 106 14 ( ( -LRB- cord-333696-3ci9re9a 106 15 including include VBG cord-333696-3ci9re9a 106 16 influenza influenza NN cord-333696-3ci9re9a 106 17 viruses virus NNS cord-333696-3ci9re9a 106 18 ) ) -RRB- cord-333696-3ci9re9a 106 19 . . . cord-333696-3ci9re9a 107 1 Intracranial intracranial JJ cord-333696-3ci9re9a 107 2 cytokine cytokine JJ cord-333696-3ci9re9a 107 3 storms storm NNS cord-333696-3ci9re9a 107 4 , , , cord-333696-3ci9re9a 107 5 with with IN cord-333696-3ci9re9a 107 6 subsequent subsequent JJ cord-333696-3ci9re9a 107 7 blood blood NN cord-333696-3ci9re9a 107 8 - - HYPH cord-333696-3ci9re9a 107 9 brain brain NN cord-333696-3ci9re9a 107 10 barrier barrier NN cord-333696-3ci9re9a 107 11 breakdown breakdown NN cord-333696-3ci9re9a 107 12 , , , cord-333696-3ci9re9a 107 13 is be VBZ cord-333696-3ci9re9a 107 14 the the DT cord-333696-3ci9re9a 107 15 most most RBS cord-333696-3ci9re9a 107 16 accepted accepted JJ cord-333696-3ci9re9a 107 17 theory theory NN cord-333696-3ci9re9a 107 18 behind behind IN cord-333696-3ci9re9a 107 19 ANE ANE NNP cord-333696-3ci9re9a 107 20 after after IN cord-333696-3ci9re9a 107 21 viral viral JJ cord-333696-3ci9re9a 107 22 infections infection NNS cord-333696-3ci9re9a 107 23 [ [ -LRB- cord-333696-3ci9re9a 107 24 60 60 CD cord-333696-3ci9re9a 107 25 ] ] -RRB- cord-333696-3ci9re9a 107 26 . . . cord-333696-3ci9re9a 108 1 Recent recent JJ cord-333696-3ci9re9a 108 2 evidence evidence NN cord-333696-3ci9re9a 108 3 showed show VBD cord-333696-3ci9re9a 108 4 that that IN cord-333696-3ci9re9a 108 5 patients patient NNS cord-333696-3ci9re9a 108 6 with with IN cord-333696-3ci9re9a 108 7 severe severe JJ cord-333696-3ci9re9a 108 8 COVID-19 covid-19 NN cord-333696-3ci9re9a 108 9 might may MD cord-333696-3ci9re9a 108 10 have have VB cord-333696-3ci9re9a 108 11 a a DT cord-333696-3ci9re9a 108 12 cytokine cytokine NN cord-333696-3ci9re9a 108 13 storm storm NN cord-333696-3ci9re9a 108 14 syndrome syndrome NN cord-333696-3ci9re9a 108 15 [ [ -LRB- cord-333696-3ci9re9a 108 16 61 61 CD cord-333696-3ci9re9a 108 17 ] ] -RRB- cord-333696-3ci9re9a 108 18 . . . cord-333696-3ci9re9a 109 1 Poyiadji Poyiadji NNP cord-333696-3ci9re9a 109 2 et et FW cord-333696-3ci9re9a 109 3 al al NNP cord-333696-3ci9re9a 109 4 . . . cord-333696-3ci9re9a 110 1 ( ( -LRB- cord-333696-3ci9re9a 110 2 2020 2020 CD cord-333696-3ci9re9a 110 3 ) ) -RRB- cord-333696-3ci9re9a 110 4 were be VBD cord-333696-3ci9re9a 110 5 the the DT cord-333696-3ci9re9a 110 6 first first JJ cord-333696-3ci9re9a 110 7 to to TO cord-333696-3ci9re9a 110 8 report report VB cord-333696-3ci9re9a 110 9 a a DT cord-333696-3ci9re9a 110 10 case case NN cord-333696-3ci9re9a 110 11 of of IN cord-333696-3ci9re9a 110 12 ANE ANE NNP cord-333696-3ci9re9a 110 13 in in IN cord-333696-3ci9re9a 110 14 a a DT cord-333696-3ci9re9a 110 15 COVID-19 covid-19 JJ cord-333696-3ci9re9a 110 16 patient patient NN cord-333696-3ci9re9a 110 17 . . . cord-333696-3ci9re9a 111 1 A a DT cord-333696-3ci9re9a 111 2 female female NN cord-333696-3ci9re9a 111 3 in in IN cord-333696-3ci9re9a 111 4 her -PRON- PRP$ cord-333696-3ci9re9a 111 5 fifties fifty NNS cord-333696-3ci9re9a 111 6 presented present VBN cord-333696-3ci9re9a 111 7 with with IN cord-333696-3ci9re9a 111 8 a a DT cord-333696-3ci9re9a 111 9 3-day 3-day JJ cord-333696-3ci9re9a 111 10 history history NN cord-333696-3ci9re9a 111 11 of of IN cord-333696-3ci9re9a 111 12 fever fever NN cord-333696-3ci9re9a 111 13 , , , cord-333696-3ci9re9a 111 14 cough cough NN cord-333696-3ci9re9a 111 15 , , , cord-333696-3ci9re9a 111 16 and and CC cord-333696-3ci9re9a 111 17 altered alter VBN cord-333696-3ci9re9a 111 18 mental mental JJ cord-333696-3ci9re9a 111 19 status status NN cord-333696-3ci9re9a 111 20 . . . cord-333696-3ci9re9a 112 1 Laboratory laboratory NN cord-333696-3ci9re9a 112 2 work work NN cord-333696-3ci9re9a 112 3 - - HYPH cord-333696-3ci9re9a 112 4 up up NN cord-333696-3ci9re9a 112 5 was be VBD cord-333696-3ci9re9a 112 6 negative negative JJ cord-333696-3ci9re9a 112 7 for for IN cord-333696-3ci9re9a 112 8 influenza influenza NN cord-333696-3ci9re9a 112 9 , , , cord-333696-3ci9re9a 112 10 with with IN cord-333696-3ci9re9a 112 11 the the DT cord-333696-3ci9re9a 112 12 diagnosis diagnosis NN cord-333696-3ci9re9a 112 13 of of IN cord-333696-3ci9re9a 112 14 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 112 15 made make VBN cord-333696-3ci9re9a 112 16 by by IN cord-333696-3ci9re9a 112 17 detection detection NN cord-333696-3ci9re9a 112 18 of of IN cord-333696-3ci9re9a 112 19 severe severe JJ cord-333696-3ci9re9a 112 20 acute acute JJ cord-333696-3ci9re9a 112 21 respiratory respiratory JJ cord-333696-3ci9re9a 112 22 syndrome syndrome NN cord-333696-3ci9re9a 112 23 coronavirus coronavirus NN cord-333696-3ci9re9a 112 24 2 2 CD cord-333696-3ci9re9a 112 25 ( ( -LRB- cord-333696-3ci9re9a 112 26 SARS SARS NNP cord-333696-3ci9re9a 112 27 - - HYPH cord-333696-3ci9re9a 112 28 CoV2 CoV2 NNP cord-333696-3ci9re9a 112 29 ) ) -RRB- cord-333696-3ci9re9a 112 30 PCR PCR NNP cord-333696-3ci9re9a 112 31 . . . cord-333696-3ci9re9a 113 1 CSF CSF NNP cord-333696-3ci9re9a 113 2 bacterial bacterial JJ cord-333696-3ci9re9a 113 3 culture culture NN cord-333696-3ci9re9a 113 4 showed show VBD cord-333696-3ci9re9a 113 5 no no DT cord-333696-3ci9re9a 113 6 growth growth NN cord-333696-3ci9re9a 113 7 after after IN cord-333696-3ci9re9a 113 8 3 3 CD cord-333696-3ci9re9a 113 9 days day NNS cord-333696-3ci9re9a 113 10 , , , cord-333696-3ci9re9a 113 11 and and CC cord-333696-3ci9re9a 113 12 tests test NNS cord-333696-3ci9re9a 113 13 for for IN cord-333696-3ci9re9a 113 14 herpes herpes NNP cord-333696-3ci9re9a 113 15 simplex simplex NNP cord-333696-3ci9re9a 113 16 virus virus NN cord-333696-3ci9re9a 113 17 1 1 CD cord-333696-3ci9re9a 113 18 and and CC cord-333696-3ci9re9a 113 19 2 2 CD cord-333696-3ci9re9a 113 20 , , , cord-333696-3ci9re9a 113 21 varicellazoster varicellazoster NNP cord-333696-3ci9re9a 113 22 virus virus NN cord-333696-3ci9re9a 113 23 , , , cord-333696-3ci9re9a 113 24 and and CC cord-333696-3ci9re9a 113 25 West West NNP cord-333696-3ci9re9a 113 26 Nile Nile NNP cord-333696-3ci9re9a 113 27 virus virus NN cord-333696-3ci9re9a 113 28 were be VBD cord-333696-3ci9re9a 113 29 negative negative JJ cord-333696-3ci9re9a 113 30 . . . cord-333696-3ci9re9a 114 1 Testing test VBG cord-333696-3ci9re9a 114 2 for for IN cord-333696-3ci9re9a 114 3 the the DT cord-333696-3ci9re9a 114 4 presence presence NN cord-333696-3ci9re9a 114 5 of of IN cord-333696-3ci9re9a 114 6 SARS SARS NNP cord-333696-3ci9re9a 114 7 - - HYPH cord-333696-3ci9re9a 114 8 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 114 9 in in IN cord-333696-3ci9re9a 114 10 the the DT cord-333696-3ci9re9a 114 11 CSF CSF NNP cord-333696-3ci9re9a 114 12 was be VBD cord-333696-3ci9re9a 114 13 unable unable JJ cord-333696-3ci9re9a 114 14 to to TO cord-333696-3ci9re9a 114 15 be be VB cord-333696-3ci9re9a 114 16 performed perform VBN cord-333696-3ci9re9a 114 17 . . . cord-333696-3ci9re9a 115 1 CT CT NNP cord-333696-3ci9re9a 115 2 scan scan NNP cord-333696-3ci9re9a 115 3 demonstrated demonstrate VBD cord-333696-3ci9re9a 115 4 symmetric symmetric JJ cord-333696-3ci9re9a 115 5 hypoattenuation hypoattenuation NN cord-333696-3ci9re9a 115 6 within within IN cord-333696-3ci9re9a 115 7 the the DT cord-333696-3ci9re9a 115 8 bilateral bilateral JJ cord-333696-3ci9re9a 115 9 medial medial JJ cord-333696-3ci9re9a 115 10 thalami thalami NN cord-333696-3ci9re9a 115 11 , , , cord-333696-3ci9re9a 115 12 and and CC cord-333696-3ci9re9a 115 13 CT CT NNP cord-333696-3ci9re9a 115 14 angiogram angiogram NN cord-333696-3ci9re9a 115 15 and and CC cord-333696-3ci9re9a 115 16 CT CT NNP cord-333696-3ci9re9a 115 17 venogram venogram NNP cord-333696-3ci9re9a 115 18 were be VBD cord-333696-3ci9re9a 115 19 negative negative JJ cord-333696-3ci9re9a 115 20 . . . cord-333696-3ci9re9a 116 1 Brain Brain NNP cord-333696-3ci9re9a 116 2 MRI MRI NNP cord-333696-3ci9re9a 116 3 showed show VBD cord-333696-3ci9re9a 116 4 hemorrhagic hemorrhagic JJ cord-333696-3ci9re9a 116 5 rim rim NN cord-333696-3ci9re9a 116 6 enhancing enhance VBG cord-333696-3ci9re9a 116 7 lesions lesion NNS cord-333696-3ci9re9a 116 8 within within IN cord-333696-3ci9re9a 116 9 the the DT cord-333696-3ci9re9a 116 10 bilateral bilateral JJ cord-333696-3ci9re9a 116 11 thalami thalami NN cord-333696-3ci9re9a 116 12 , , , cord-333696-3ci9re9a 116 13 medial medial JJ cord-333696-3ci9re9a 116 14 temporal temporal JJ cord-333696-3ci9re9a 116 15 lobes lobe NNS cord-333696-3ci9re9a 116 16 , , , cord-333696-3ci9re9a 116 17 and and CC cord-333696-3ci9re9a 116 18 subinsular subinsular JJ cord-333696-3ci9re9a 116 19 regions region NNS cord-333696-3ci9re9a 116 20 . . . cord-333696-3ci9re9a 117 1 These these DT cord-333696-3ci9re9a 117 2 imaging imaging NN cord-333696-3ci9re9a 117 3 findings finding NNS cord-333696-3ci9re9a 117 4 were be VBD cord-333696-3ci9re9a 117 5 consistent consistent JJ cord-333696-3ci9re9a 117 6 with with IN cord-333696-3ci9re9a 117 7 ANE ANE NNP cord-333696-3ci9re9a 117 8 and and CC cord-333696-3ci9re9a 117 9 they -PRON- PRP cord-333696-3ci9re9a 117 10 concluded conclude VBD cord-333696-3ci9re9a 117 11 that that IN cord-333696-3ci9re9a 117 12 ANE ANE NNP cord-333696-3ci9re9a 117 13 was be VBD cord-333696-3ci9re9a 117 14 caused cause VBN cord-333696-3ci9re9a 117 15 by by IN cord-333696-3ci9re9a 117 16 SARS SARS NNP cord-333696-3ci9re9a 117 17 - - HYPH cord-333696-3ci9re9a 117 18 CoV2 CoV2 NNP cord-333696-3ci9re9a 117 19 . . . cord-333696-3ci9re9a 118 1 The the DT cord-333696-3ci9re9a 118 2 authors author NNS cord-333696-3ci9re9a 118 3 reported report VBD cord-333696-3ci9re9a 118 4 that that IN cord-333696-3ci9re9a 118 5 the the DT cord-333696-3ci9re9a 118 6 patient patient NN cord-333696-3ci9re9a 118 7 was be VBD cord-333696-3ci9re9a 118 8 treated treat VBN cord-333696-3ci9re9a 118 9 by by IN cord-333696-3ci9re9a 118 10 intravenous intravenous JJ cord-333696-3ci9re9a 118 11 immunoglobulin immunoglobulin NN cord-333696-3ci9re9a 118 12 but but CC cord-333696-3ci9re9a 118 13 high high JJ cord-333696-3ci9re9a 118 14 - - HYPH cord-333696-3ci9re9a 118 15 dose dose NN cord-333696-3ci9re9a 118 16 steroids steroid NNS cord-333696-3ci9re9a 118 17 were be VBD cord-333696-3ci9re9a 118 18 not not RB cord-333696-3ci9re9a 118 19 initiated initiate VBN cord-333696-3ci9re9a 118 20 due due IN cord-333696-3ci9re9a 118 21 to to IN cord-333696-3ci9re9a 118 22 concern concern NN cord-333696-3ci9re9a 118 23 for for IN cord-333696-3ci9re9a 118 24 respiratory respiratory JJ cord-333696-3ci9re9a 118 25 compromise compromise NN cord-333696-3ci9re9a 118 26 [ [ -LRB- cord-333696-3ci9re9a 118 27 62 62 CD cord-333696-3ci9re9a 118 28 ] ] -RRB- cord-333696-3ci9re9a 118 29 . . . cord-333696-3ci9re9a 119 1 More more RBR cord-333696-3ci9re9a 119 2 recently recently RB cord-333696-3ci9re9a 119 3 , , , cord-333696-3ci9re9a 119 4 Dixon Dixon NNP cord-333696-3ci9re9a 119 5 et et NNP cord-333696-3ci9re9a 119 6 al al NNP cord-333696-3ci9re9a 119 7 . . . cord-333696-3ci9re9a 120 1 ( ( -LRB- cord-333696-3ci9re9a 120 2 2020 2020 CD cord-333696-3ci9re9a 120 3 ) ) -RRB- cord-333696-3ci9re9a 120 4 reported report VBD cord-333696-3ci9re9a 120 5 another another DT cord-333696-3ci9re9a 120 6 case case NN cord-333696-3ci9re9a 120 7 of of IN cord-333696-3ci9re9a 120 8 ANE ANE NNP cord-333696-3ci9re9a 120 9 in in IN cord-333696-3ci9re9a 120 10 a a DT cord-333696-3ci9re9a 120 11 53-year 53-year JJ cord-333696-3ci9re9a 120 12 - - HYPH cord-333696-3ci9re9a 120 13 old old JJ cord-333696-3ci9re9a 120 14 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 120 15 patient patient NN cord-333696-3ci9re9a 120 16 with with IN cord-333696-3ci9re9a 120 17 aplastic aplastic JJ cord-333696-3ci9re9a 120 18 anemia anemia NN cord-333696-3ci9re9a 120 19 [ [ -LRB- cord-333696-3ci9re9a 120 20 63 63 CD cord-333696-3ci9re9a 120 21 ] ] -RRB- cord-333696-3ci9re9a 120 22 . . . cord-333696-3ci9re9a 121 1 The the DT cord-333696-3ci9re9a 121 2 patient patient NN cord-333696-3ci9re9a 121 3 present present JJ cord-333696-3ci9re9a 121 4 10 10 CD cord-333696-3ci9re9a 121 5 days day NNS cord-333696-3ci9re9a 121 6 after after IN cord-333696-3ci9re9a 121 7 onset onset NN cord-333696-3ci9re9a 121 8 of of IN cord-333696-3ci9re9a 121 9 symptoms symptom NNS cord-333696-3ci9re9a 121 10 and and CC cord-333696-3ci9re9a 121 11 was be VBD cord-333696-3ci9re9a 121 12 shown show VBN cord-333696-3ci9re9a 121 13 to to TO cord-333696-3ci9re9a 121 14 have have VB cord-333696-3ci9re9a 121 15 swelling swelling NN cord-333696-3ci9re9a 121 16 in in IN cord-333696-3ci9re9a 121 17 the the DT cord-333696-3ci9re9a 121 18 brainstem brainstem NN cord-333696-3ci9re9a 121 19 on on IN cord-333696-3ci9re9a 121 20 CT CT NNP cord-333696-3ci9re9a 121 21 scan scan NN cord-333696-3ci9re9a 121 22 . . . cord-333696-3ci9re9a 122 1 Brain Brain NNP cord-333696-3ci9re9a 122 2 MRI MRI NNP cord-333696-3ci9re9a 122 3 showed show VBD cord-333696-3ci9re9a 122 4 multiple multiple JJ cord-333696-3ci9re9a 122 5 symmetric symmetric JJ cord-333696-3ci9re9a 122 6 hemorrhagic hemorrhagic JJ cord-333696-3ci9re9a 122 7 lesions lesion NNS cord-333696-3ci9re9a 122 8 in in IN cord-333696-3ci9re9a 122 9 the the DT cord-333696-3ci9re9a 122 10 brainstem brainstem NN cord-333696-3ci9re9a 122 11 and and CC cord-333696-3ci9re9a 122 12 different different JJ cord-333696-3ci9re9a 122 13 nuclei nucleus NNS cord-333696-3ci9re9a 122 14 . . . cord-333696-3ci9re9a 123 1 The the DT cord-333696-3ci9re9a 123 2 patient patient NN cord-333696-3ci9re9a 123 3 died die VBD cord-333696-3ci9re9a 123 4 8 8 CD cord-333696-3ci9re9a 123 5 days day NNS cord-333696-3ci9re9a 123 6 after after IN cord-333696-3ci9re9a 123 7 hospital hospital NN cord-333696-3ci9re9a 123 8 admission admission NN cord-333696-3ci9re9a 123 9 [ [ -LRB- cord-333696-3ci9re9a 123 10 63 63 CD cord-333696-3ci9re9a 123 11 ] ] -RRB- cord-333696-3ci9re9a 123 12 . . . cord-333696-3ci9re9a 124 1 Leukoencephalopathy Leukoencephalopathy NNP cord-333696-3ci9re9a 124 2 is be VBZ cord-333696-3ci9re9a 124 3 the the DT cord-333696-3ci9re9a 124 4 name name NN cord-333696-3ci9re9a 124 5 given give VBN cord-333696-3ci9re9a 124 6 to to IN cord-333696-3ci9re9a 124 7 the the DT cord-333696-3ci9re9a 124 8 group group NN cord-333696-3ci9re9a 124 9 of of IN cord-333696-3ci9re9a 124 10 diseases disease NNS cord-333696-3ci9re9a 124 11 that that WDT cord-333696-3ci9re9a 124 12 affect affect VBP cord-333696-3ci9re9a 124 13 the the DT cord-333696-3ci9re9a 124 14 white white JJ cord-333696-3ci9re9a 124 15 matter matter NN cord-333696-3ci9re9a 124 16 of of IN cord-333696-3ci9re9a 124 17 the the DT cord-333696-3ci9re9a 124 18 central central JJ cord-333696-3ci9re9a 124 19 nervous nervous JJ cord-333696-3ci9re9a 124 20 system system NN cord-333696-3ci9re9a 124 21 [ [ -LRB- cord-333696-3ci9re9a 124 22 64 64 CD cord-333696-3ci9re9a 124 23 ] ] -RRB- cord-333696-3ci9re9a 124 24 . . . cord-333696-3ci9re9a 125 1 Since since IN cord-333696-3ci9re9a 125 2 the the DT cord-333696-3ci9re9a 125 3 beginning beginning NN cord-333696-3ci9re9a 125 4 of of IN cord-333696-3ci9re9a 125 5 the the DT cord-333696-3ci9re9a 125 6 COVID-19 covid-19 JJ cord-333696-3ci9re9a 125 7 pandemic pandemic NN cord-333696-3ci9re9a 125 8 , , , cord-333696-3ci9re9a 125 9 many many JJ cord-333696-3ci9re9a 125 10 reports report NNS cord-333696-3ci9re9a 125 11 [ [ -LRB- cord-333696-3ci9re9a 125 12 68 68 CD cord-333696-3ci9re9a 125 13 ] ] -RRB- cord-333696-3ci9re9a 125 14 . . . cord-333696-3ci9re9a 126 1 Although although IN cord-333696-3ci9re9a 126 2 it -PRON- PRP cord-333696-3ci9re9a 126 3 is be VBZ cord-333696-3ci9re9a 126 4 mandatory mandatory JJ cord-333696-3ci9re9a 126 5 to to TO cord-333696-3ci9re9a 126 6 rule rule VB cord-333696-3ci9re9a 126 7 out out RP cord-333696-3ci9re9a 126 8 other other JJ cord-333696-3ci9re9a 126 9 etiologies etiology NNS cord-333696-3ci9re9a 126 10 in in IN cord-333696-3ci9re9a 126 11 these these DT cord-333696-3ci9re9a 126 12 critical critical JJ cord-333696-3ci9re9a 126 13 patients patient NNS cord-333696-3ci9re9a 126 14 , , , cord-333696-3ci9re9a 126 15 such such JJ cord-333696-3ci9re9a 126 16 as as IN cord-333696-3ci9re9a 126 17 hemorrhagic hemorrhagic JJ cord-333696-3ci9re9a 126 18 encephalopathy encephalopathy NN cord-333696-3ci9re9a 126 19 , , , cord-333696-3ci9re9a 126 20 sepsis sepsis NN cord-333696-3ci9re9a 126 21 - - HYPH cord-333696-3ci9re9a 126 22 associated associate VBN cord-333696-3ci9re9a 126 23 encephalopathy encephalopathy NN cord-333696-3ci9re9a 126 24 , , , cord-333696-3ci9re9a 126 25 posterior posterior JJ cord-333696-3ci9re9a 126 26 reversible reversible JJ cord-333696-3ci9re9a 126 27 encephalopathy encephalopathy NN cord-333696-3ci9re9a 126 28 syndrome syndrome NN cord-333696-3ci9re9a 126 29 in in IN cord-333696-3ci9re9a 126 30 addition addition NN cord-333696-3ci9re9a 126 31 to to IN cord-333696-3ci9re9a 126 32 other other JJ cord-333696-3ci9re9a 126 33 toxic toxic JJ cord-333696-3ci9re9a 126 34 and and CC cord-333696-3ci9re9a 126 35 metabolic metabolic JJ cord-333696-3ci9re9a 126 36 causes cause NNS cord-333696-3ci9re9a 126 37 [ [ -LRB- cord-333696-3ci9re9a 126 38 68 68 CD cord-333696-3ci9re9a 126 39 ] ] -RRB- cord-333696-3ci9re9a 126 40 , , , cord-333696-3ci9re9a 126 41 leukoencephalopathy leukoencephalopathy NNP cord-333696-3ci9re9a 126 42 should should MD cord-333696-3ci9re9a 126 43 be be VB cord-333696-3ci9re9a 126 44 considered consider VBN cord-333696-3ci9re9a 126 45 in in IN cord-333696-3ci9re9a 126 46 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 126 47 patients patient NNS cord-333696-3ci9re9a 126 48 . . . cord-333696-3ci9re9a 127 1 Acute acute JJ cord-333696-3ci9re9a 127 2 Disseminated disseminate VBN cord-333696-3ci9re9a 127 3 encephalomyelitis encephalomyelitis NN cord-333696-3ci9re9a 127 4 ( ( -LRB- cord-333696-3ci9re9a 127 5 ADEM ADEM NNP cord-333696-3ci9re9a 127 6 ) ) -RRB- cord-333696-3ci9re9a 127 7 is be VBZ cord-333696-3ci9re9a 127 8 an an DT cord-333696-3ci9re9a 127 9 autoimmune autoimmune JJ cord-333696-3ci9re9a 127 10 demyelinating demyelinate VBG cord-333696-3ci9re9a 127 11 disease disease NN cord-333696-3ci9re9a 127 12 of of IN cord-333696-3ci9re9a 127 13 the the DT cord-333696-3ci9re9a 127 14 CNS CNS NNP cord-333696-3ci9re9a 127 15 characterized characterize VBN cord-333696-3ci9re9a 127 16 by by IN cord-333696-3ci9re9a 127 17 a a DT cord-333696-3ci9re9a 127 18 sudden sudden JJ cord-333696-3ci9re9a 127 19 and and CC cord-333696-3ci9re9a 127 20 widespread widespread JJ cord-333696-3ci9re9a 127 21 inflammation inflammation NN cord-333696-3ci9re9a 127 22 . . . cord-333696-3ci9re9a 128 1 It -PRON- PRP cord-333696-3ci9re9a 128 2 affects affect VBZ cord-333696-3ci9re9a 128 3 mainly mainly RB cord-333696-3ci9re9a 128 4 children child NNS cord-333696-3ci9re9a 128 5 and and CC cord-333696-3ci9re9a 128 6 younger young JJR cord-333696-3ci9re9a 128 7 adults adult NNS cord-333696-3ci9re9a 128 8 , , , cord-333696-3ci9re9a 128 9 and and CC cord-333696-3ci9re9a 128 10 it -PRON- PRP cord-333696-3ci9re9a 128 11 is be VBZ cord-333696-3ci9re9a 128 12 usually usually RB cord-333696-3ci9re9a 128 13 triggered trigger VBN cord-333696-3ci9re9a 128 14 by by IN cord-333696-3ci9re9a 128 15 viral viral JJ cord-333696-3ci9re9a 128 16 infections infection NNS cord-333696-3ci9re9a 128 17 , , , cord-333696-3ci9re9a 128 18 but but CC cord-333696-3ci9re9a 128 19 unlike unlike IN cord-333696-3ci9re9a 128 20 viral viral JJ cord-333696-3ci9re9a 128 21 encephalitis encephalitis RB cord-333696-3ci9re9a 128 22 , , , cord-333696-3ci9re9a 128 23 it -PRON- PRP cord-333696-3ci9re9a 128 24 is be VBZ cord-333696-3ci9re9a 128 25 not not RB cord-333696-3ci9re9a 128 26 due due JJ cord-333696-3ci9re9a 128 27 to to IN cord-333696-3ci9re9a 128 28 viral viral JJ cord-333696-3ci9re9a 128 29 neuroinvasion neuroinvasion NN cord-333696-3ci9re9a 128 30 [ [ -LRB- cord-333696-3ci9re9a 128 31 69 69 CD cord-333696-3ci9re9a 128 32 ] ] -RRB- cord-333696-3ci9re9a 128 33 . . . cord-333696-3ci9re9a 129 1 No no DT cord-333696-3ci9re9a 129 2 cases case NNS cord-333696-3ci9re9a 129 3 of of IN cord-333696-3ci9re9a 129 4 ADEM ADEM NNP cord-333696-3ci9re9a 129 5 in in IN cord-333696-3ci9re9a 129 6 patients patient NNS cord-333696-3ci9re9a 129 7 with with IN cord-333696-3ci9re9a 129 8 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 129 9 have have VBP cord-333696-3ci9re9a 129 10 been be VBN cord-333696-3ci9re9a 129 11 reported report VBN cord-333696-3ci9re9a 129 12 in in IN cord-333696-3ci9re9a 129 13 the the DT cord-333696-3ci9re9a 129 14 literature literature NN cord-333696-3ci9re9a 129 15 yet yet RB cord-333696-3ci9re9a 129 16 . . . cord-333696-3ci9re9a 130 1 However however RB cord-333696-3ci9re9a 130 2 , , , cord-333696-3ci9re9a 130 3 there there EX cord-333696-3ci9re9a 130 4 is be VBZ cord-333696-3ci9re9a 130 5 a a DT cord-333696-3ci9re9a 130 6 case case NN cord-333696-3ci9re9a 130 7 of of IN cord-333696-3ci9re9a 130 8 a a DT cord-333696-3ci9re9a 130 9 15-year 15-year JJ cord-333696-3ci9re9a 130 10 old old JJ cord-333696-3ci9re9a 130 11 boy boy NN cord-333696-3ci9re9a 130 12 that that WDT cord-333696-3ci9re9a 130 13 presented present VBD cord-333696-3ci9re9a 130 14 to to IN cord-333696-3ci9re9a 130 15 the the DT cord-333696-3ci9re9a 130 16 Children Children NNPS cord-333696-3ci9re9a 130 17 's 's POS cord-333696-3ci9re9a 130 18 Hospital Hospital NNP cord-333696-3ci9re9a 130 19 of of IN cord-333696-3ci9re9a 130 20 Buffalo Buffalo NNP cord-333696-3ci9re9a 130 21 with with IN cord-333696-3ci9re9a 130 22 signs sign NNS cord-333696-3ci9re9a 130 23 and and CC cord-333696-3ci9re9a 130 24 symptoms symptom NNS cord-333696-3ci9re9a 130 25 of of IN cord-333696-3ci9re9a 130 26 ADEM ADEM NNP cord-333696-3ci9re9a 130 27 while while IN cord-333696-3ci9re9a 130 28 also also RB cord-333696-3ci9re9a 130 29 reporting report VBG cord-333696-3ci9re9a 130 30 a a DT cord-333696-3ci9re9a 130 31 history history NN cord-333696-3ci9re9a 130 32 of of IN cord-333696-3ci9re9a 130 33 an an DT cord-333696-3ci9re9a 130 34 upper upper JJ cord-333696-3ci9re9a 130 35 respiratory respiratory JJ cord-333696-3ci9re9a 130 36 tract tract NN cord-333696-3ci9re9a 130 37 infection infection NN cord-333696-3ci9re9a 130 38 a a DT cord-333696-3ci9re9a 130 39 week week NN cord-333696-3ci9re9a 130 40 before before IN cord-333696-3ci9re9a 130 41 [ [ -LRB- cord-333696-3ci9re9a 130 42 70 70 CD cord-333696-3ci9re9a 130 43 ] ] -RRB- cord-333696-3ci9re9a 130 44 . . . cord-333696-3ci9re9a 131 1 This this DT cord-333696-3ci9re9a 131 2 patient patient NN cord-333696-3ci9re9a 131 3 was be VBD cord-333696-3ci9re9a 131 4 given give VBN cord-333696-3ci9re9a 131 5 a a DT cord-333696-3ci9re9a 131 6 presumed presume VBN cord-333696-3ci9re9a 131 7 diagnosed diagnose VBN cord-333696-3ci9re9a 131 8 of of IN cord-333696-3ci9re9a 131 9 ADEM ADEM NNP cord-333696-3ci9re9a 131 10 ( ( -LRB- cord-333696-3ci9re9a 131 11 MS MS NNP cord-333696-3ci9re9a 131 12 could could MD cord-333696-3ci9re9a 131 13 not not RB cord-333696-3ci9re9a 131 14 be be VB cord-333696-3ci9re9a 131 15 ruled rule VBN cord-333696-3ci9re9a 131 16 out out RP cord-333696-3ci9re9a 131 17 ) ) -RRB- cord-333696-3ci9re9a 131 18 and and CC cord-333696-3ci9re9a 131 19 was be VBD cord-333696-3ci9re9a 131 20 found find VBN cord-333696-3ci9re9a 131 21 to to TO cord-333696-3ci9re9a 131 22 have have VB cord-333696-3ci9re9a 131 23 Human Human NNP cord-333696-3ci9re9a 131 24 Coronavirus Coronavirus NNP cord-333696-3ci9re9a 131 25 OC43 OC43 NNP cord-333696-3ci9re9a 131 26 ( ( -LRB- cord-333696-3ci9re9a 131 27 HCoV HCoV NNP cord-333696-3ci9re9a 131 28 - - HYPH cord-333696-3ci9re9a 131 29 OC43 OC43 NNP cord-333696-3ci9re9a 131 30 ) ) -RRB- cord-333696-3ci9re9a 131 31 in in IN cord-333696-3ci9re9a 131 32 his -PRON- PRP$ cord-333696-3ci9re9a 131 33 CSF csf NN cord-333696-3ci9re9a 131 34 and and CC cord-333696-3ci9re9a 131 35 nasopharyngeal nasopharyngeal JJ cord-333696-3ci9re9a 131 36 secretions secretion NNS cord-333696-3ci9re9a 131 37 by by IN cord-333696-3ci9re9a 131 38 RT RT NNP cord-333696-3ci9re9a 131 39 - - HYPH cord-333696-3ci9re9a 131 40 PCR PCR NNP cord-333696-3ci9re9a 131 41 . . . cord-333696-3ci9re9a 132 1 This this DT cord-333696-3ci9re9a 132 2 was be VBD cord-333696-3ci9re9a 132 3 the the DT cord-333696-3ci9re9a 132 4 first first JJ cord-333696-3ci9re9a 132 5 reported report VBN cord-333696-3ci9re9a 132 6 case case NN cord-333696-3ci9re9a 132 7 of of IN cord-333696-3ci9re9a 132 8 coronavirus coronavirus NN cord-333696-3ci9re9a 132 9 - - HYPH cord-333696-3ci9re9a 132 10 associated associate VBN cord-333696-3ci9re9a 132 11 demyelinating demyelinate VBG cord-333696-3ci9re9a 132 12 disease disease NN cord-333696-3ci9re9a 132 13 in in IN cord-333696-3ci9re9a 132 14 a a DT cord-333696-3ci9re9a 132 15 pediatric pediatric JJ cord-333696-3ci9re9a 132 16 patient patient NN cord-333696-3ci9re9a 132 17 . . . cord-333696-3ci9re9a 133 1 While while IN cord-333696-3ci9re9a 133 2 SARS SARS NNP cord-333696-3ci9re9a 133 3 - - HYPH cord-333696-3ci9re9a 133 4 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 133 5 is be VBZ cord-333696-3ci9re9a 133 6 not not RB cord-333696-3ci9re9a 133 7 yet yet RB cord-333696-3ci9re9a 133 8 associated associate VBN cord-333696-3ci9re9a 133 9 with with IN cord-333696-3ci9re9a 133 10 such such JJ cord-333696-3ci9re9a 133 11 cases case NNS cord-333696-3ci9re9a 133 12 , , , cord-333696-3ci9re9a 133 13 HCoV HCoV NNP cord-333696-3ci9re9a 133 14 - - HYPH cord-333696-3ci9re9a 133 15 OC43 OC43 NNP cord-333696-3ci9re9a 133 16 is be VBZ cord-333696-3ci9re9a 133 17 a a DT cord-333696-3ci9re9a 133 18 member member NN cord-333696-3ci9re9a 133 19 of of IN cord-333696-3ci9re9a 133 20 the the DT cord-333696-3ci9re9a 133 21 betacoronavirus betacoronavirus NNP cord-333696-3ci9re9a 133 22 family family NN cord-333696-3ci9re9a 133 23 to to TO cord-333696-3ci9re9a 133 24 which which WDT cord-333696-3ci9re9a 133 25 SASR SASR NNP cord-333696-3ci9re9a 133 26 - - : cord-333696-3ci9re9a 133 27 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 133 28 also also RB cord-333696-3ci9re9a 133 29 belongs belong VBZ cord-333696-3ci9re9a 133 30 . . . cord-333696-3ci9re9a 134 1 In in IN cord-333696-3ci9re9a 134 2 addition addition NN cord-333696-3ci9re9a 134 3 , , , cord-333696-3ci9re9a 134 4 the the DT cord-333696-3ci9re9a 134 5 two two CD cord-333696-3ci9re9a 134 6 viruses virus NNS cord-333696-3ci9re9a 134 7 were be VBD cord-333696-3ci9re9a 134 8 shown show VBN cord-333696-3ci9re9a 134 9 J J NNP cord-333696-3ci9re9a 134 10 o o NN cord-333696-3ci9re9a 134 11 u u NN cord-333696-3ci9re9a 134 12 r r NN cord-333696-3ci9re9a 134 13 n n NN cord-333696-3ci9re9a 134 14 a a DT cord-333696-3ci9re9a 134 15 l l NN cord-333696-3ci9re9a 134 16 P p NN cord-333696-3ci9re9a 134 17 r r NN cord-333696-3ci9re9a 134 18 e e NN cord-333696-3ci9re9a 134 19 -p -p NN cord-333696-3ci9re9a 134 20 r r NN cord-333696-3ci9re9a 134 21 o o NN cord-333696-3ci9re9a 134 22 o o NN cord-333696-3ci9re9a 134 23 f f NN cord-333696-3ci9re9a 134 24 to to TO cord-333696-3ci9re9a 134 25 be be VB cord-333696-3ci9re9a 134 26 closely closely RB cord-333696-3ci9re9a 134 27 related relate VBN cord-333696-3ci9re9a 134 28 phylogenetically phylogenetically RB cord-333696-3ci9re9a 134 29 and and CC cord-333696-3ci9re9a 134 30 are be VBP cord-333696-3ci9re9a 134 31 two two CD cord-333696-3ci9re9a 134 32 of of IN cord-333696-3ci9re9a 134 33 the the DT cord-333696-3ci9re9a 134 34 only only JJ cord-333696-3ci9re9a 134 35 seven seven CD cord-333696-3ci9re9a 134 36 known know VBN cord-333696-3ci9re9a 134 37 human human JJ cord-333696-3ci9re9a 134 38 coronaviruses coronaviruse NNS cord-333696-3ci9re9a 134 39 [ [ -LRB- cord-333696-3ci9re9a 134 40 71 71 CD cord-333696-3ci9re9a 134 41 ] ] -RRB- cord-333696-3ci9re9a 134 42 . . . cord-333696-3ci9re9a 135 1 Although although IN cord-333696-3ci9re9a 135 2 we -PRON- PRP cord-333696-3ci9re9a 135 3 have have VBP cord-333696-3ci9re9a 135 4 evidence evidence NN cord-333696-3ci9re9a 135 5 that that IN cord-333696-3ci9re9a 135 6 respiratory respiratory NN cord-333696-3ci9re9a 135 7 - - HYPH cord-333696-3ci9re9a 135 8 related relate VBN cord-333696-3ci9re9a 135 9 infections infection NNS cord-333696-3ci9re9a 135 10 are be VBP cord-333696-3ci9re9a 135 11 an an DT cord-333696-3ci9re9a 135 12 independent independent JJ cord-333696-3ci9re9a 135 13 risk risk NN cord-333696-3ci9re9a 135 14 factor factor NN cord-333696-3ci9re9a 135 15 for for IN cord-333696-3ci9re9a 135 16 acute acute JJ cord-333696-3ci9re9a 135 17 cerebrovascular cerebrovascular JJ cord-333696-3ci9re9a 135 18 events event NNS cord-333696-3ci9re9a 135 19 [ [ -LRB- cord-333696-3ci9re9a 135 20 72 72 CD cord-333696-3ci9re9a 135 21 , , , cord-333696-3ci9re9a 135 22 73 73 CD cord-333696-3ci9re9a 135 23 ] ] -RRB- cord-333696-3ci9re9a 135 24 , , , cord-333696-3ci9re9a 135 25 evidence evidence NN cord-333696-3ci9re9a 135 26 specific specific JJ cord-333696-3ci9re9a 135 27 to to IN cord-333696-3ci9re9a 135 28 SARS SARS NNP cord-333696-3ci9re9a 135 29 - - HYPH cord-333696-3ci9re9a 135 30 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 135 31 infection infection NN cord-333696-3ci9re9a 135 32 is be VBZ cord-333696-3ci9re9a 135 33 still still RB cord-333696-3ci9re9a 135 34 far far RB cord-333696-3ci9re9a 135 35 from from IN cord-333696-3ci9re9a 135 36 conclusive conclusive JJ cord-333696-3ci9re9a 135 37 . . . cord-333696-3ci9re9a 136 1 Strokes stroke NNS cord-333696-3ci9re9a 136 2 were be VBD cord-333696-3ci9re9a 136 3 reported report VBN cord-333696-3ci9re9a 136 4 to to TO cord-333696-3ci9re9a 136 5 have have VB cord-333696-3ci9re9a 136 6 an an DT cord-333696-3ci9re9a 136 7 incidence incidence NN cord-333696-3ci9re9a 136 8 close close JJ cord-333696-3ci9re9a 136 9 to to IN cord-333696-3ci9re9a 136 10 2 2 CD cord-333696-3ci9re9a 136 11 % % NN cord-333696-3ci9re9a 136 12 in in IN cord-333696-3ci9re9a 136 13 hospitalized hospitalize VBN cord-333696-3ci9re9a 136 14 patients patient NNS cord-333696-3ci9re9a 136 15 with with IN cord-333696-3ci9re9a 136 16 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 136 17 [ [ -LRB- cord-333696-3ci9re9a 136 18 8 8 CD cord-333696-3ci9re9a 136 19 ] ] -RRB- cord-333696-3ci9re9a 136 20 . . . cord-333696-3ci9re9a 137 1 One one CD cord-333696-3ci9re9a 137 2 of of IN cord-333696-3ci9re9a 137 3 the the DT cord-333696-3ci9re9a 137 4 early early JJ cord-333696-3ci9re9a 137 5 studies study NNS cord-333696-3ci9re9a 137 6 in in IN cord-333696-3ci9re9a 137 7 this this DT cord-333696-3ci9re9a 137 8 field field NN cord-333696-3ci9re9a 137 9 was be VBD cord-333696-3ci9re9a 137 10 done do VBN cord-333696-3ci9re9a 137 11 by by IN cord-333696-3ci9re9a 137 12 Muhammad Muhammad NNP cord-333696-3ci9re9a 137 13 et et NNP cord-333696-3ci9re9a 137 14 al al NNP cord-333696-3ci9re9a 137 15 . . . cord-333696-3ci9re9a 138 1 ( ( -LRB- cord-333696-3ci9re9a 138 2 2011 2011 CD cord-333696-3ci9re9a 138 3 ) ) -RRB- cord-333696-3ci9re9a 138 4 on on IN cord-333696-3ci9re9a 138 5 experimental experimental JJ cord-333696-3ci9re9a 138 6 mouse mouse NN cord-333696-3ci9re9a 138 7 models model NNS cord-333696-3ci9re9a 138 8 and and CC cord-333696-3ci9re9a 138 9 suggested suggest VBD cord-333696-3ci9re9a 138 10 that that IN cord-333696-3ci9re9a 138 11 influenza influenza NN cord-333696-3ci9re9a 138 12 virus virus NN cord-333696-3ci9re9a 138 13 can can MD cord-333696-3ci9re9a 138 14 aggravate aggravate VB cord-333696-3ci9re9a 138 15 ischemic ischemic JJ cord-333696-3ci9re9a 138 16 brain brain NN cord-333696-3ci9re9a 138 17 injury injury NN cord-333696-3ci9re9a 138 18 via via IN cord-333696-3ci9re9a 138 19 triggering trigger VBG cord-333696-3ci9re9a 138 20 a a DT cord-333696-3ci9re9a 138 21 cytokine cytokine NN cord-333696-3ci9re9a 138 22 cascade cascade NN cord-333696-3ci9re9a 138 23 and and CC cord-333696-3ci9re9a 138 24 can can MD cord-333696-3ci9re9a 138 25 increase increase VB cord-333696-3ci9re9a 138 26 the the DT cord-333696-3ci9re9a 138 27 risk risk NN cord-333696-3ci9re9a 138 28 of of IN cord-333696-3ci9re9a 138 29 cerebral cerebral JJ cord-333696-3ci9re9a 138 30 hemorrhage hemorrhage NN cord-333696-3ci9re9a 138 31 after after IN cord-333696-3ci9re9a 138 32 treatment treatment NN cord-333696-3ci9re9a 138 33 with with IN cord-333696-3ci9re9a 138 34 tissue tissue NN cord-333696-3ci9re9a 138 35 - - HYPH cord-333696-3ci9re9a 138 36 type type NN cord-333696-3ci9re9a 138 37 plasminogen plasminogen NN cord-333696-3ci9re9a 138 38 activator activator NN cord-333696-3ci9re9a 138 39 [ [ -LRB- cord-333696-3ci9re9a 138 40 74 74 CD cord-333696-3ci9re9a 138 41 ] ] -RRB- cord-333696-3ci9re9a 138 42 . . . cord-333696-3ci9re9a 139 1 The the DT cord-333696-3ci9re9a 139 2 infection infection NN cord-333696-3ci9re9a 139 3 of of IN cord-333696-3ci9re9a 139 4 CoV cov NN cord-333696-3ci9re9a 139 5 , , , cord-333696-3ci9re9a 139 6 especially especially RB cord-333696-3ci9re9a 139 7 SARS SARS NNP cord-333696-3ci9re9a 139 8 - - HYPH cord-333696-3ci9re9a 139 9 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 139 10 , , , cord-333696-3ci9re9a 139 11 has have VBZ cord-333696-3ci9re9a 139 12 been be VBN cord-333696-3ci9re9a 139 13 widely widely RB cord-333696-3ci9re9a 139 14 reported report VBN cord-333696-3ci9re9a 139 15 to to TO cord-333696-3ci9re9a 139 16 cause cause VB cord-333696-3ci9re9a 139 17 cytokine cytokine JJ cord-333696-3ci9re9a 139 18 storm storm NN cord-333696-3ci9re9a 139 19 syndromes syndrome NNS cord-333696-3ci9re9a 139 20 , , , cord-333696-3ci9re9a 139 21 which which WDT cord-333696-3ci9re9a 139 22 may may MD cord-333696-3ci9re9a 139 23 be be VB cord-333696-3ci9re9a 139 24 one one CD cord-333696-3ci9re9a 139 25 of of IN cord-333696-3ci9re9a 139 26 the the DT cord-333696-3ci9re9a 139 27 factors factor NNS cord-333696-3ci9re9a 139 28 that that WDT cord-333696-3ci9re9a 139 29 CoV cov NN cord-333696-3ci9re9a 139 30 causes cause VBZ cord-333696-3ci9re9a 139 31 acute acute JJ cord-333696-3ci9re9a 139 32 cerebrovascular cerebrovascular JJ cord-333696-3ci9re9a 139 33 disease disease NN cord-333696-3ci9re9a 139 34 [ [ -LRB- cord-333696-3ci9re9a 139 35 15 15 CD cord-333696-3ci9re9a 139 36 , , , cord-333696-3ci9re9a 139 37 61 61 CD cord-333696-3ci9re9a 139 38 ] ] -RRB- cord-333696-3ci9re9a 139 39 . . . cord-333696-3ci9re9a 140 1 In in IN cord-333696-3ci9re9a 140 2 addition addition NN cord-333696-3ci9re9a 140 3 , , , cord-333696-3ci9re9a 140 4 critically critically RB cord-333696-3ci9re9a 140 5 ill ill JJ cord-333696-3ci9re9a 140 6 patients patient NNS cord-333696-3ci9re9a 140 7 with with IN cord-333696-3ci9re9a 140 8 severe severe JJ cord-333696-3ci9re9a 140 9 SARS SARS NNP cord-333696-3ci9re9a 140 10 - - HYPH cord-333696-3ci9re9a 140 11 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 140 12 infections infection NNS cord-333696-3ci9re9a 140 13 often often RB cord-333696-3ci9re9a 140 14 show show VBP cord-333696-3ci9re9a 140 15 elevated elevated JJ cord-333696-3ci9re9a 140 16 levels level NNS cord-333696-3ci9re9a 140 17 of of IN cord-333696-3ci9re9a 140 18 D d NN cord-333696-3ci9re9a 140 19 - - HYPH cord-333696-3ci9re9a 140 20 dimer dimer NN cord-333696-3ci9re9a 140 21 and and CC cord-333696-3ci9re9a 140 22 severe severe JJ cord-333696-3ci9re9a 140 23 platelet platelet NN cord-333696-3ci9re9a 140 24 reduction reduction NN cord-333696-3ci9re9a 140 25 , , , cord-333696-3ci9re9a 140 26 which which WDT cord-333696-3ci9re9a 140 27 may may MD cord-333696-3ci9re9a 140 28 render render VB cord-333696-3ci9re9a 140 29 these these DT cord-333696-3ci9re9a 140 30 patients patient NNS cord-333696-3ci9re9a 140 31 prone prone JJ cord-333696-3ci9re9a 140 32 to to IN cord-333696-3ci9re9a 140 33 acute acute JJ cord-333696-3ci9re9a 140 34 cerebrovascular cerebrovascular JJ cord-333696-3ci9re9a 140 35 events event NNS cord-333696-3ci9re9a 140 36 [ [ -LRB- cord-333696-3ci9re9a 140 37 37 37 CD cord-333696-3ci9re9a 140 38 ] ] -RRB- cord-333696-3ci9re9a 140 39 . . . cord-333696-3ci9re9a 141 1 Interestingly interestingly RB cord-333696-3ci9re9a 141 2 , , , cord-333696-3ci9re9a 141 3 several several JJ cord-333696-3ci9re9a 141 4 recent recent JJ cord-333696-3ci9re9a 141 5 reports report NNS cord-333696-3ci9re9a 141 6 showed show VBD cord-333696-3ci9re9a 141 7 that that IN cord-333696-3ci9re9a 141 8 COVID-19 covid-19 CD cord-333696-3ci9re9a 141 9 patients patient NNS cord-333696-3ci9re9a 141 10 have have VBP cord-333696-3ci9re9a 141 11 a a DT cord-333696-3ci9re9a 141 12 propensity propensity NN cord-333696-3ci9re9a 141 13 to to TO cord-333696-3ci9re9a 141 14 develop develop VB cord-333696-3ci9re9a 141 15 a a DT cord-333696-3ci9re9a 141 16 hypercoagulable hypercoagulable JJ cord-333696-3ci9re9a 141 17 state state NN cord-333696-3ci9re9a 141 18 [ [ -LRB- cord-333696-3ci9re9a 141 19 75 75 CD cord-333696-3ci9re9a 141 20 ] ] -RRB- cord-333696-3ci9re9a 141 21 [ [ -LRB- cord-333696-3ci9re9a 141 22 76 76 CD cord-333696-3ci9re9a 141 23 ] ] -RRB- cord-333696-3ci9re9a 141 24 [ [ -LRB- cord-333696-3ci9re9a 141 25 77 77 CD cord-333696-3ci9re9a 141 26 ] ] -RRB- cord-333696-3ci9re9a 141 27 [ [ -LRB- cord-333696-3ci9re9a 141 28 78 78 CD cord-333696-3ci9re9a 141 29 ] ] -RRB- cord-333696-3ci9re9a 141 30 . . . cord-333696-3ci9re9a 142 1 A a DT cord-333696-3ci9re9a 142 2 brief brief JJ cord-333696-3ci9re9a 142 3 report report NN cord-333696-3ci9re9a 142 4 of of IN cord-333696-3ci9re9a 142 5 three three CD cord-333696-3ci9re9a 142 6 COVID-19 covid-19 CD cord-333696-3ci9re9a 142 7 patients patient NNS cord-333696-3ci9re9a 142 8 , , , cord-333696-3ci9re9a 142 9 who who WP cord-333696-3ci9re9a 142 10 were be VBD cord-333696-3ci9re9a 142 11 young young JJ cord-333696-3ci9re9a 142 12 ( ( -LRB- cord-333696-3ci9re9a 142 13 mean mean VB cord-333696-3ci9re9a 142 14 age age NN cord-333696-3ci9re9a 142 15 of of IN cord-333696-3ci9re9a 142 16 34 34 CD cord-333696-3ci9re9a 142 17 years year NNS cord-333696-3ci9re9a 142 18 ) ) -RRB- cord-333696-3ci9re9a 142 19 and and CC cord-333696-3ci9re9a 142 20 previously previously RB cord-333696-3ci9re9a 142 21 healthy healthy JJ cord-333696-3ci9re9a 142 22 , , , cord-333696-3ci9re9a 142 23 with with IN cord-333696-3ci9re9a 142 24 only only RB cord-333696-3ci9re9a 142 25 one one CD cord-333696-3ci9re9a 142 26 of of IN cord-333696-3ci9re9a 142 27 the the DT cord-333696-3ci9re9a 142 28 three three CD cord-333696-3ci9re9a 142 29 having have VBG cord-333696-3ci9re9a 142 30 a a DT cord-333696-3ci9re9a 142 31 risk risk NN cord-333696-3ci9re9a 142 32 factor factor NN cord-333696-3ci9re9a 142 33 for for IN cord-333696-3ci9re9a 142 34 hypercoagulability hypercoagulability NN cord-333696-3ci9re9a 142 35 ( ( -LRB- cord-333696-3ci9re9a 142 36 oral oral JJ cord-333696-3ci9re9a 142 37 contraceptives contraceptive NNS cord-333696-3ci9re9a 142 38 ) ) -RRB- cord-333696-3ci9re9a 142 39 eventually eventually RB cord-333696-3ci9re9a 142 40 developed develop VBD cord-333696-3ci9re9a 142 41 cerebral cerebral JJ cord-333696-3ci9re9a 142 42 venous venous JJ cord-333696-3ci9re9a 142 43 thrombosis thrombosis NN cord-333696-3ci9re9a 142 44 following follow VBG cord-333696-3ci9re9a 142 45 their -PRON- PRP$ cord-333696-3ci9re9a 142 46 infection infection NN cord-333696-3ci9re9a 142 47 [ [ -LRB- cord-333696-3ci9re9a 142 48 79 79 CD cord-333696-3ci9re9a 142 49 ] ] -RRB- cord-333696-3ci9re9a 142 50 . . . cord-333696-3ci9re9a 143 1 In in IN cord-333696-3ci9re9a 143 2 addition addition NN cord-333696-3ci9re9a 143 3 , , , cord-333696-3ci9re9a 143 4 a a DT cord-333696-3ci9re9a 143 5 retrospective retrospective JJ cord-333696-3ci9re9a 143 6 cohort cohort NN cord-333696-3ci9re9a 143 7 study study NN cord-333696-3ci9re9a 143 8 in in IN cord-333696-3ci9re9a 143 9 New New NNP cord-333696-3ci9re9a 143 10 York York NNP cord-333696-3ci9re9a 143 11 City City NNP cord-333696-3ci9re9a 143 12 , , , cord-333696-3ci9re9a 143 13 showed show VBD cord-333696-3ci9re9a 143 14 that that IN cord-333696-3ci9re9a 143 15 COVID-19 covid-19 CD cord-333696-3ci9re9a 143 16 patients patient NNS cord-333696-3ci9re9a 143 17 had have VBD cord-333696-3ci9re9a 143 18 higher high JJR cord-333696-3ci9re9a 143 19 National National NNP cord-333696-3ci9re9a 143 20 Institutes Institutes NNPS cord-333696-3ci9re9a 143 21 of of IN cord-333696-3ci9re9a 143 22 Health Health NNP cord-333696-3ci9re9a 143 23 Stroke Stroke NNP cord-333696-3ci9re9a 143 24 Scale Scale NNP cord-333696-3ci9re9a 143 25 scores score NNS cord-333696-3ci9re9a 143 26 at at IN cord-333696-3ci9re9a 143 27 admission admission NN cord-333696-3ci9re9a 143 28 , , , cord-333696-3ci9re9a 143 29 in in IN cord-333696-3ci9re9a 143 30 addition addition NN cord-333696-3ci9re9a 143 31 to to IN cord-333696-3ci9re9a 143 32 higher high JJR cord-333696-3ci9re9a 143 33 peak peak NN cord-333696-3ci9re9a 143 34 D d NN cord-333696-3ci9re9a 143 35 - - HYPH cord-333696-3ci9re9a 143 36 dimer dimer NN cord-333696-3ci9re9a 143 37 values value NNS cord-333696-3ci9re9a 143 38 and and CC cord-333696-3ci9re9a 143 39 a a DT cord-333696-3ci9re9a 143 40 significantly significantly RB cord-333696-3ci9re9a 143 41 higher high JJR cord-333696-3ci9re9a 143 42 mortality mortality NN cord-333696-3ci9re9a 143 43 rate rate NN cord-333696-3ci9re9a 143 44 when when WRB cord-333696-3ci9re9a 143 45 compared compare VBN cord-333696-3ci9re9a 143 46 with with IN cord-333696-3ci9re9a 143 47 non non JJ cord-333696-3ci9re9a 143 48 - - JJ cord-333696-3ci9re9a 143 49 infected infected JJ cord-333696-3ci9re9a 143 50 patients patient NNS cord-333696-3ci9re9a 143 51 with with IN cord-333696-3ci9re9a 143 52 strokes stroke NNS cord-333696-3ci9re9a 143 53 [ [ -LRB- cord-333696-3ci9re9a 143 54 80 80 CD cord-333696-3ci9re9a 143 55 , , , cord-333696-3ci9re9a 143 56 81 81 CD cord-333696-3ci9re9a 143 57 ] ] -RRB- cord-333696-3ci9re9a 143 58 . . . cord-333696-3ci9re9a 143 59 _SP cord-333696-3ci9re9a 144 1 Although although IN cord-333696-3ci9re9a 144 2 there there EX cord-333696-3ci9re9a 144 3 are be VBP cord-333696-3ci9re9a 144 4 no no DT cord-333696-3ci9re9a 144 5 other other JJ cord-333696-3ci9re9a 144 6 reports report NNS cord-333696-3ci9re9a 144 7 on on IN cord-333696-3ci9re9a 144 8 electroencephalography electroencephalography NN cord-333696-3ci9re9a 144 9 findings finding NNS cord-333696-3ci9re9a 144 10 in in IN cord-333696-3ci9re9a 144 11 COVID-19 covid-19 CD cord-333696-3ci9re9a 144 12 patients patient NNS cord-333696-3ci9re9a 144 13 , , , cord-333696-3ci9re9a 144 14 it -PRON- PRP cord-333696-3ci9re9a 144 15 is be VBZ cord-333696-3ci9re9a 144 16 worth worth JJ cord-333696-3ci9re9a 144 17 mentioning mention VBG cord-333696-3ci9re9a 144 18 that that IN cord-333696-3ci9re9a 144 19 Helms Helms NNP cord-333696-3ci9re9a 144 20 et et NNP cord-333696-3ci9re9a 144 21 al al NNP cord-333696-3ci9re9a 144 22 . . . cord-333696-3ci9re9a 145 1 reported report VBN cord-333696-3ci9re9a 145 2 in in IN cord-333696-3ci9re9a 145 3 their -PRON- PRP$ cord-333696-3ci9re9a 145 4 paper paper NN cord-333696-3ci9re9a 145 5 that that IN cord-333696-3ci9re9a 145 6 in in IN cord-333696-3ci9re9a 145 7 the the DT cord-333696-3ci9re9a 145 8 8 8 CD cord-333696-3ci9re9a 145 9 patients patient NNS cord-333696-3ci9re9a 145 10 who who WP cord-333696-3ci9re9a 145 11 underwent undergo VBD cord-333696-3ci9re9a 145 12 electroencephalography electroencephalography NN cord-333696-3ci9re9a 145 13 , , , cord-333696-3ci9re9a 145 14 only only RB cord-333696-3ci9re9a 145 15 nonspecific nonspecific JJ cord-333696-3ci9re9a 145 16 changes change NNS cord-333696-3ci9re9a 145 17 were be VBD cord-333696-3ci9re9a 145 18 detected detect VBN cord-333696-3ci9re9a 145 19 ; ; : cord-333696-3ci9re9a 145 20 and and CC cord-333696-3ci9re9a 145 21 only only RB cord-333696-3ci9re9a 145 22 one one CD cord-333696-3ci9re9a 145 23 patient patient NN cord-333696-3ci9re9a 145 24 had have VBD cord-333696-3ci9re9a 145 25 diffuse diffuse JJ cord-333696-3ci9re9a 145 26 bifrontal bifrontal JJ cord-333696-3ci9re9a 145 27 slowing slow VBG cord-333696-3ci9re9a 145 28 consistent consistent JJ cord-333696-3ci9re9a 145 29 with with IN cord-333696-3ci9re9a 145 30 encephalopathy encephalopathy NN cord-333696-3ci9re9a 145 31 [ [ -LRB- cord-333696-3ci9re9a 145 32 82 82 CD cord-333696-3ci9re9a 145 33 ] ] -RRB- cord-333696-3ci9re9a 145 34 . . . cord-333696-3ci9re9a 146 1 Similarly similarly RB cord-333696-3ci9re9a 146 2 , , , cord-333696-3ci9re9a 146 3 Filatov Filatov NNP cord-333696-3ci9re9a 146 4 et et NNP cord-333696-3ci9re9a 146 5 al al NNP cord-333696-3ci9re9a 146 6 . . . cord-333696-3ci9re9a 147 1 ( ( -LRB- cord-333696-3ci9re9a 147 2 2020 2020 CD cord-333696-3ci9re9a 147 3 ) ) -RRB- cord-333696-3ci9re9a 147 4 reported report VBD cord-333696-3ci9re9a 147 5 EEG EEG NNP cord-333696-3ci9re9a 147 6 findings finding NNS cord-333696-3ci9re9a 147 7 of of IN cord-333696-3ci9re9a 147 8 bilateral bilateral JJ cord-333696-3ci9re9a 147 9 slowing slowing NN cord-333696-3ci9re9a 147 10 and and CC cord-333696-3ci9re9a 147 11 focal focal JJ cord-333696-3ci9re9a 147 12 slowing slowing NN cord-333696-3ci9re9a 147 13 in in IN cord-333696-3ci9re9a 147 14 the the DT cord-333696-3ci9re9a 147 15 left left JJ cord-333696-3ci9re9a 147 16 temporal temporal JJ cord-333696-3ci9re9a 147 17 region region NN cord-333696-3ci9re9a 147 18 with with IN cord-333696-3ci9re9a 147 19 sharply sharply RB cord-333696-3ci9re9a 147 20 countered counter VBN cord-333696-3ci9re9a 147 21 waves wave NNS cord-333696-3ci9re9a 147 22 in in IN cord-333696-3ci9re9a 147 23 patients patient NNS cord-333696-3ci9re9a 147 24 with with IN cord-333696-3ci9re9a 147 25 COVID-19 covid-19 JJ cord-333696-3ci9re9a 147 26 associated associated JJ cord-333696-3ci9re9a 147 27 encephalopathy encephalopathy NN cord-333696-3ci9re9a 147 28 [ [ -LRB- cord-333696-3ci9re9a 147 29 83 83 CD cord-333696-3ci9re9a 147 30 ] ] -RRB- cord-333696-3ci9re9a 147 31 . . . cord-333696-3ci9re9a 148 1 J J NNP cord-333696-3ci9re9a 148 2 o o NN cord-333696-3ci9re9a 148 3 u u NN cord-333696-3ci9re9a 148 4 r r NN cord-333696-3ci9re9a 148 5 n n NN cord-333696-3ci9re9a 148 6 a a DT cord-333696-3ci9re9a 148 7 l l NN cord-333696-3ci9re9a 148 8 P p NN cord-333696-3ci9re9a 148 9 r r NN cord-333696-3ci9re9a 148 10 e e NN cord-333696-3ci9re9a 148 11 -p -p NN cord-333696-3ci9re9a 148 12 r r NN cord-333696-3ci9re9a 148 13 o o NN cord-333696-3ci9re9a 148 14 o o NN cord-333696-3ci9re9a 148 15 f f NN cord-333696-3ci9re9a 148 16 Helms Helms NNP cord-333696-3ci9re9a 148 17 et et NNP cord-333696-3ci9re9a 148 18 al al NNP cord-333696-3ci9re9a 148 19 . . NNP cord-333696-3ci9re9a 148 20 reported report VBD cord-333696-3ci9re9a 148 21 that that IN cord-333696-3ci9re9a 148 22 CSF CSF NNP cord-333696-3ci9re9a 148 23 samples sample NNS cord-333696-3ci9re9a 148 24 obtained obtain VBN cord-333696-3ci9re9a 148 25 from from IN cord-333696-3ci9re9a 148 26 7 7 CD cord-333696-3ci9re9a 148 27 patients patient NNS cord-333696-3ci9re9a 148 28 were be VBD cord-333696-3ci9re9a 148 29 all all DT cord-333696-3ci9re9a 148 30 negative negative JJ cord-333696-3ci9re9a 148 31 for for IN cord-333696-3ci9re9a 148 32 SARS SARS NNP cord-333696-3ci9re9a 148 33 - - HYPH cord-333696-3ci9re9a 148 34 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 148 35 and and CC cord-333696-3ci9re9a 148 36 none none NN cord-333696-3ci9re9a 148 37 showed show VBD cord-333696-3ci9re9a 148 38 cells cell NNS cord-333696-3ci9re9a 148 39 . . . cord-333696-3ci9re9a 149 1 However however RB cord-333696-3ci9re9a 149 2 , , , cord-333696-3ci9re9a 149 3 examination examination NN cord-333696-3ci9re9a 149 4 of of IN cord-333696-3ci9re9a 149 5 CSF CSF NNP cord-333696-3ci9re9a 149 6 samples sample NNS cord-333696-3ci9re9a 149 7 revealed reveal VBD cord-333696-3ci9re9a 149 8 oligoclonal oligoclonal JJ cord-333696-3ci9re9a 149 9 bands band NNS cord-333696-3ci9re9a 149 10 were be VBD cord-333696-3ci9re9a 149 11 present present JJ cord-333696-3ci9re9a 149 12 in in IN cord-333696-3ci9re9a 149 13 2 2 CD cord-333696-3ci9re9a 149 14 patients patient NNS cord-333696-3ci9re9a 149 15 , , , cord-333696-3ci9re9a 149 16 with with IN cord-333696-3ci9re9a 149 17 an an DT cord-333696-3ci9re9a 149 18 identical identical JJ cord-333696-3ci9re9a 149 19 electrophoretic electrophoretic JJ cord-333696-3ci9re9a 149 20 pattern pattern NN cord-333696-3ci9re9a 149 21 in in IN cord-333696-3ci9re9a 149 22 serum serum NN cord-333696-3ci9re9a 149 23 . . . cord-333696-3ci9re9a 150 1 Protein protein NN cord-333696-3ci9re9a 150 2 and and CC cord-333696-3ci9re9a 150 3 IgG igg NN cord-333696-3ci9re9a 150 4 levels level NNS cord-333696-3ci9re9a 150 5 were be VBD cord-333696-3ci9re9a 150 6 elevated elevate VBN cord-333696-3ci9re9a 150 7 in in IN cord-333696-3ci9re9a 150 8 1 1 CD cord-333696-3ci9re9a 150 9 patient patient NN cord-333696-3ci9re9a 150 10 [ [ -LRB- cord-333696-3ci9re9a 150 11 82 82 CD cord-333696-3ci9re9a 150 12 ] ] -RRB- cord-333696-3ci9re9a 150 13 . . . cord-333696-3ci9re9a 151 1 These these DT cord-333696-3ci9re9a 151 2 findings finding NNS cord-333696-3ci9re9a 151 3 might may MD cord-333696-3ci9re9a 151 4 support support VB cord-333696-3ci9re9a 151 5 the the DT cord-333696-3ci9re9a 151 6 theory theory NN cord-333696-3ci9re9a 151 7 that that IN cord-333696-3ci9re9a 151 8 the the DT cord-333696-3ci9re9a 151 9 SARS SARS NNP cord-333696-3ci9re9a 151 10 - - HYPH cord-333696-3ci9re9a 151 11 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 151 12 can can MD cord-333696-3ci9re9a 151 13 cause cause VB cord-333696-3ci9re9a 151 14 neurologic neurologic JJ cord-333696-3ci9re9a 151 15 manifestations manifestation NNS cord-333696-3ci9re9a 151 16 indirectly indirectly RB cord-333696-3ci9re9a 151 17 , , , cord-333696-3ci9re9a 151 18 probably probably RB cord-333696-3ci9re9a 151 19 by by IN cord-333696-3ci9re9a 151 20 triggering trigger VBG cord-333696-3ci9re9a 151 21 a a DT cord-333696-3ci9re9a 151 22 reaction reaction NN cord-333696-3ci9re9a 151 23 , , , cord-333696-3ci9re9a 151 24 rather rather RB cord-333696-3ci9re9a 151 25 than than IN cord-333696-3ci9re9a 151 26 by by IN cord-333696-3ci9re9a 151 27 direct direct JJ cord-333696-3ci9re9a 151 28 invasion invasion NN cord-333696-3ci9re9a 151 29 of of IN cord-333696-3ci9re9a 151 30 the the DT cord-333696-3ci9re9a 151 31 nervous nervous JJ cord-333696-3ci9re9a 151 32 system system NN cord-333696-3ci9re9a 151 33 , , , cord-333696-3ci9re9a 151 34 although although IN cord-333696-3ci9re9a 151 35 CSF CSF NNP cord-333696-3ci9re9a 151 36 was be VBD cord-333696-3ci9re9a 151 37 found find VBN cord-333696-3ci9re9a 151 38 to to TO cord-333696-3ci9re9a 151 39 be be VB cord-333696-3ci9re9a 151 40 positive positive JJ cord-333696-3ci9re9a 151 41 for for IN cord-333696-3ci9re9a 151 42 SARS SARS NNP cord-333696-3ci9re9a 151 43 - - HYPH cord-333696-3ci9re9a 151 44 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 151 45 in in IN cord-333696-3ci9re9a 151 46 another another DT cord-333696-3ci9re9a 151 47 report report NN cord-333696-3ci9re9a 151 48 [ [ -LRB- cord-333696-3ci9re9a 151 49 46 46 CD cord-333696-3ci9re9a 151 50 ] ] -RRB- cord-333696-3ci9re9a 151 51 . . . cord-333696-3ci9re9a 152 1 As as IN cord-333696-3ci9re9a 152 2 the the DT cord-333696-3ci9re9a 152 3 number number NN cord-333696-3ci9re9a 152 4 of of IN cord-333696-3ci9re9a 152 5 patients patient NNS cord-333696-3ci9re9a 152 6 with with IN cord-333696-3ci9re9a 152 7 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 152 8 is be VBZ cord-333696-3ci9re9a 152 9 increasing increase VBG cord-333696-3ci9re9a 152 10 worldwide worldwide RB cord-333696-3ci9re9a 152 11 , , , cord-333696-3ci9re9a 152 12 it -PRON- PRP cord-333696-3ci9re9a 152 13 is be VBZ cord-333696-3ci9re9a 152 14 necessary necessary JJ cord-333696-3ci9re9a 152 15 to to TO cord-333696-3ci9re9a 152 16 stress stress VB cord-333696-3ci9re9a 152 17 on on IN cord-333696-3ci9re9a 152 18 the the DT cord-333696-3ci9re9a 152 19 importance importance NN cord-333696-3ci9re9a 152 20 of of IN cord-333696-3ci9re9a 152 21 the the DT cord-333696-3ci9re9a 152 22 atypical atypical JJ cord-333696-3ci9re9a 152 23 clinical clinical JJ cord-333696-3ci9re9a 152 24 presentations presentation NNS cord-333696-3ci9re9a 152 25 ( ( -LRB- cord-333696-3ci9re9a 152 26 including include VBG cord-333696-3ci9re9a 152 27 those those DT cord-333696-3ci9re9a 152 28 related relate VBN cord-333696-3ci9re9a 152 29 to to IN cord-333696-3ci9re9a 152 30 the the DT cord-333696-3ci9re9a 152 31 nervous nervous JJ cord-333696-3ci9re9a 152 32 system system NN cord-333696-3ci9re9a 152 33 ) ) -RRB- cord-333696-3ci9re9a 152 34 of of IN cord-333696-3ci9re9a 152 35 COVID-19 covid-19 JJ cord-333696-3ci9re9a 152 36 infection infection NN cord-333696-3ci9re9a 152 37 , , , cord-333696-3ci9re9a 152 38 since since IN cord-333696-3ci9re9a 152 39 they -PRON- PRP cord-333696-3ci9re9a 152 40 might may MD cord-333696-3ci9re9a 152 41 be be VB cord-333696-3ci9re9a 152 42 the the DT cord-333696-3ci9re9a 152 43 initial initial JJ cord-333696-3ci9re9a 152 44 manifestations manifestation NNS cord-333696-3ci9re9a 152 45 . . . cord-333696-3ci9re9a 153 1 Patients patient NNS cord-333696-3ci9re9a 153 2 with with IN cord-333696-3ci9re9a 153 3 COVID-19 covid-19 JJ cord-333696-3ci9re9a 153 4 infection infection NN cord-333696-3ci9re9a 153 5 should should MD cord-333696-3ci9re9a 153 6 be be VB cord-333696-3ci9re9a 153 7 evaluated evaluate VBN cord-333696-3ci9re9a 153 8 early early RB cord-333696-3ci9re9a 153 9 for for IN cord-333696-3ci9re9a 153 10 neurological neurological JJ cord-333696-3ci9re9a 153 11 symptoms symptom NNS cord-333696-3ci9re9a 153 12 . . . cord-333696-3ci9re9a 154 1 Timely timely JJ cord-333696-3ci9re9a 154 2 analysis analysis NN cord-333696-3ci9re9a 154 3 of of IN cord-333696-3ci9re9a 154 4 cerebrospinal cerebrospinal JJ cord-333696-3ci9re9a 154 5 fluid fluid NN cord-333696-3ci9re9a 154 6 and and CC cord-333696-3ci9re9a 154 7 early early JJ cord-333696-3ci9re9a 154 8 appropriate appropriate JJ cord-333696-3ci9re9a 154 9 management management NN cord-333696-3ci9re9a 154 10 of of IN cord-333696-3ci9re9a 154 11 infection infection NN cord-333696-3ci9re9a 154 12 - - HYPH cord-333696-3ci9re9a 154 13 related relate VBN cord-333696-3ci9re9a 154 14 neurological neurological JJ cord-333696-3ci9re9a 154 15 complications complication NNS cord-333696-3ci9re9a 154 16 might may MD cord-333696-3ci9re9a 154 17 be be VB cord-333696-3ci9re9a 154 18 the the DT cord-333696-3ci9re9a 154 19 key key NN cord-333696-3ci9re9a 154 20 to to TO cord-333696-3ci9re9a 154 21 improve improve VB cord-333696-3ci9re9a 154 22 the the DT cord-333696-3ci9re9a 154 23 prognosis prognosis NN cord-333696-3ci9re9a 154 24 of of IN cord-333696-3ci9re9a 154 25 critically critically RB cord-333696-3ci9re9a 154 26 ill ill JJ cord-333696-3ci9re9a 154 27 patients patient NNS cord-333696-3ci9re9a 154 28 . . . cord-333696-3ci9re9a 155 1 Since since IN cord-333696-3ci9re9a 155 2 health health NN cord-333696-3ci9re9a 155 3 - - HYPH cord-333696-3ci9re9a 155 4 care care NN cord-333696-3ci9re9a 155 5 providers provider NNS cord-333696-3ci9re9a 155 6 might may MD cord-333696-3ci9re9a 155 7 under under RB cord-333696-3ci9re9a 155 8 - - : cord-333696-3ci9re9a 155 9 recognize recognize VB cord-333696-3ci9re9a 155 10 these these DT cord-333696-3ci9re9a 155 11 cases case NNS cord-333696-3ci9re9a 155 12 with with IN cord-333696-3ci9re9a 155 13 atypical atypical JJ cord-333696-3ci9re9a 155 14 presentations presentation NNS cord-333696-3ci9re9a 155 15 , , , cord-333696-3ci9re9a 155 16 and and CC cord-333696-3ci9re9a 155 17 these these DT cord-333696-3ci9re9a 155 18 patients patient NNS cord-333696-3ci9re9a 155 19 may may MD cord-333696-3ci9re9a 155 20 represent represent VB cord-333696-3ci9re9a 155 21 a a DT cord-333696-3ci9re9a 155 22 hidden hidden JJ cord-333696-3ci9re9a 155 23 source source NN cord-333696-3ci9re9a 155 24 of of IN cord-333696-3ci9re9a 155 25 the the DT cord-333696-3ci9re9a 155 26 spread spread NN cord-333696-3ci9re9a 155 27 of of IN cord-333696-3ci9re9a 155 28 the the DT cord-333696-3ci9re9a 155 29 virus virus NN cord-333696-3ci9re9a 155 30 , , , cord-333696-3ci9re9a 155 31 we -PRON- PRP cord-333696-3ci9re9a 155 32 believe believe VBP cord-333696-3ci9re9a 155 33 that that IN cord-333696-3ci9re9a 155 34 literature literature NN cord-333696-3ci9re9a 155 35 on on IN cord-333696-3ci9re9a 155 36 this this DT cord-333696-3ci9re9a 155 37 regard regard NN cord-333696-3ci9re9a 155 38 should should MD cord-333696-3ci9re9a 155 39 be be VB cord-333696-3ci9re9a 155 40 sent send VBN cord-333696-3ci9re9a 155 41 by by IN cord-333696-3ci9re9a 155 42 the the DT cord-333696-3ci9re9a 155 43 international international JJ cord-333696-3ci9re9a 155 44 and and CC cord-333696-3ci9re9a 155 45 local local JJ cord-333696-3ci9re9a 155 46 health health NN cord-333696-3ci9re9a 155 47 committees committee NNS cord-333696-3ci9re9a 155 48 to to IN cord-333696-3ci9re9a 155 49 all all DT cord-333696-3ci9re9a 155 50 health health NN cord-333696-3ci9re9a 155 51 - - HYPH cord-333696-3ci9re9a 155 52 care care NN cord-333696-3ci9re9a 155 53 providers provider NNS cord-333696-3ci9re9a 155 54 during during IN cord-333696-3ci9re9a 155 55 this this DT cord-333696-3ci9re9a 155 56 COVID covid NN cord-333696-3ci9re9a 155 57 -19 -19 NN cord-333696-3ci9re9a 155 58 pandemic pandemic NN cord-333696-3ci9re9a 155 59 , , , cord-333696-3ci9re9a 155 60 to to TO cord-333696-3ci9re9a 155 61 make make VB cord-333696-3ci9re9a 155 62 sure sure JJ cord-333696-3ci9re9a 155 63 that that IN cord-333696-3ci9re9a 155 64 all all DT cord-333696-3ci9re9a 155 65 providers provider NNS cord-333696-3ci9re9a 155 66 are be VBP cord-333696-3ci9re9a 155 67 well well RB cord-333696-3ci9re9a 155 68 informed informed JJ cord-333696-3ci9re9a 155 69 and and CC cord-333696-3ci9re9a 155 70 aware aware JJ cord-333696-3ci9re9a 155 71 of of IN cord-333696-3ci9re9a 155 72 these these DT cord-333696-3ci9re9a 155 73 cases case NNS cord-333696-3ci9re9a 155 74 . . . cord-333696-3ci9re9a 156 1 Moreover moreover RB cord-333696-3ci9re9a 156 2 , , , cord-333696-3ci9re9a 156 3 awareness awareness NN cord-333696-3ci9re9a 156 4 campaigns campaign NNS cord-333696-3ci9re9a 156 5 addressing address VBG cord-333696-3ci9re9a 156 6 this this DT cord-333696-3ci9re9a 156 7 issue issue NN cord-333696-3ci9re9a 156 8 should should MD cord-333696-3ci9re9a 156 9 be be VB cord-333696-3ci9re9a 156 10 directed direct VBN cord-333696-3ci9re9a 156 11 to to IN cord-333696-3ci9re9a 156 12 the the DT cord-333696-3ci9re9a 156 13 population population NN cord-333696-3ci9re9a 156 14 . . . cord-333696-3ci9re9a 157 1 Since since IN cord-333696-3ci9re9a 157 2 we -PRON- PRP cord-333696-3ci9re9a 157 3 have have VBP cord-333696-3ci9re9a 157 4 a a DT cord-333696-3ci9re9a 157 5 scarce scarce JJ cord-333696-3ci9re9a 157 6 literature literature NN cord-333696-3ci9re9a 157 7 on on IN cord-333696-3ci9re9a 157 8 this this DT cord-333696-3ci9re9a 157 9 regard regard NN cord-333696-3ci9re9a 157 10 , , , cord-333696-3ci9re9a 157 11 more more JJR cord-333696-3ci9re9a 157 12 studies study NNS cord-333696-3ci9re9a 157 13 are be VBP cord-333696-3ci9re9a 157 14 deeply deeply RB cord-333696-3ci9re9a 157 15 needed need VBN cord-333696-3ci9re9a 157 16 to to TO cord-333696-3ci9re9a 157 17 enable enable VB cord-333696-3ci9re9a 157 18 the the DT cord-333696-3ci9re9a 157 19 concerned concerned JJ cord-333696-3ci9re9a 157 20 committees committee NNS cord-333696-3ci9re9a 157 21 to to TO cord-333696-3ci9re9a 157 22 make make VB cord-333696-3ci9re9a 157 23 evidence evidence NN cord-333696-3ci9re9a 157 24 - - HYPH cord-333696-3ci9re9a 157 25 based base VBN cord-333696-3ci9re9a 157 26 guidelines guideline NNS cord-333696-3ci9re9a 157 27 for for IN cord-333696-3ci9re9a 157 28 prevention prevention NN cord-333696-3ci9re9a 157 29 , , , cord-333696-3ci9re9a 157 30 early early JJ cord-333696-3ci9re9a 157 31 detection detection NN cord-333696-3ci9re9a 157 32 and and CC cord-333696-3ci9re9a 157 33 appropriate appropriate JJ cord-333696-3ci9re9a 157 34 management management NN cord-333696-3ci9re9a 157 35 of of IN cord-333696-3ci9re9a 157 36 these these DT cord-333696-3ci9re9a 157 37 cases case NNS cord-333696-3ci9re9a 157 38 . . . cord-333696-3ci9re9a 157 39 _SP cord-333696-3ci9re9a 158 1 Potential potential JJ cord-333696-3ci9re9a 158 2 Maternal maternal JJ cord-333696-3ci9re9a 158 3 and and CC cord-333696-3ci9re9a 158 4 Infant Infant NNP cord-333696-3ci9re9a 158 5 Outcomes Outcomes NNPS cord-333696-3ci9re9a 158 6 from from IN cord-333696-3ci9re9a 158 7 Coronavirus Coronavirus NNP cord-333696-3ci9re9a 158 8 2019-nCoV 2019-ncov CD cord-333696-3ci9re9a 159 1 ( ( -LRB- cord-333696-3ci9re9a 159 2 SARS SARS NNP cord-333696-3ci9re9a 159 3 - - HYPH cord-333696-3ci9re9a 159 4 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 159 5 ) ) -RRB- cord-333696-3ci9re9a 160 1 Infecting infect VBG cord-333696-3ci9re9a 160 2 Pregnant pregnant JJ cord-333696-3ci9re9a 160 3 Women woman NNS cord-333696-3ci9re9a 160 4 : : : cord-333696-3ci9re9a 161 1 Lessons lesson NNS cord-333696-3ci9re9a 161 2 from from IN cord-333696-3ci9re9a 161 3 SARS SARS NNP cord-333696-3ci9re9a 161 4 , , , cord-333696-3ci9re9a 161 5 MERS MERS NNP cord-333696-3ci9re9a 161 6 , , , cord-333696-3ci9re9a 161 7 and and CC cord-333696-3ci9re9a 161 8 Other other JJ cord-333696-3ci9re9a 161 9 Human Human NNP cord-333696-3ci9re9a 161 10 Coronavirus Coronavirus NNP cord-333696-3ci9re9a 161 11 Infections Infections NNPS cord-333696-3ci9re9a 161 12 . . . cord-333696-3ci9re9a 162 1 Viruses virus NNS cord-333696-3ci9re9a 163 1 Zhonghua Zhonghua NNP cord-333696-3ci9re9a 163 2 gan gan NNP cord-333696-3ci9re9a 163 3 zang zang NNP cord-333696-3ci9re9a 163 4 bing bing NNP cord-333696-3ci9re9a 163 5 za za NNP cord-333696-3ci9re9a 163 6 zhi zhi NNP cord-333696-3ci9re9a 164 1 = = NFP cord-333696-3ci9re9a 165 1 Zhonghua Zhonghua NNP cord-333696-3ci9re9a 165 2 ganzangbing ganzangbing NNP cord-333696-3ci9re9a 165 3 zazhi zazhi NNP cord-333696-3ci9re9a 165 4 = = . cord-333696-3ci9re9a 166 1 Chinese chinese JJ cord-333696-3ci9re9a 166 2 journal journal NN cord-333696-3ci9re9a 166 3 of of IN cord-333696-3ci9re9a 166 4 hepatology hepatology NNP cord-333696-3ci9re9a 166 5 Coronavirus Coronavirus NNP cord-333696-3ci9re9a 166 6 disease disease NN cord-333696-3ci9re9a 166 7 ( ( -LRB- cord-333696-3ci9re9a 167 1 COVID-19 covid-19 LS cord-333696-3ci9re9a 167 2 ) ) -RRB- cord-333696-3ci9re9a 167 3 outbreak outbreak NN cord-333696-3ci9re9a 167 4 Severe severe JJ cord-333696-3ci9re9a 167 5 acute acute JJ cord-333696-3ci9re9a 167 6 respiratory respiratory JJ cord-333696-3ci9re9a 167 7 syndrome syndrome NN cord-333696-3ci9re9a 167 8 - - HYPH cord-333696-3ci9re9a 167 9 related relate VBN cord-333696-3ci9re9a 167 10 coronavirus > XX cord-333696-3ci9re9a 169 1 : : : cord-333696-3ci9re9a 169 2 The the DT cord-333696-3ci9re9a 169 3 species specie NNS cord-333696-3ci9re9a 169 4 and and CC cord-333696-3ci9re9a 169 5 its -PRON- PRP$ cord-333696-3ci9re9a 169 6 viruses virus NNS cord-333696-3ci9re9a 169 7 -a -a : cord-333696-3ci9re9a 169 8 statement statement NN cord-333696-3ci9re9a 169 9 of of IN cord-333696-3ci9re9a 169 10 the the DT cord-333696-3ci9re9a 169 11 Coronavirus Coronavirus NNP cord-333696-3ci9re9a 169 12 Study Study NNP cord-333696-3ci9re9a 169 13 Group Group NNP cord-333696-3ci9re9a 169 14 Clinical Clinical NNP cord-333696-3ci9re9a 169 15 features feature NNS cord-333696-3ci9re9a 169 16 of of IN cord-333696-3ci9re9a 169 17 patients patient NNS cord-333696-3ci9re9a 169 18 infected infect VBN cord-333696-3ci9re9a 169 19 with with IN cord-333696-3ci9re9a 169 20 2019 2019 CD cord-333696-3ci9re9a 169 21 novel novel JJ cord-333696-3ci9re9a 169 22 coronavirus coronavirus NN cord-333696-3ci9re9a 169 23 in in IN cord-333696-3ci9re9a 169 24 Wuhan Wuhan NNP cord-333696-3ci9re9a 169 25 , , , cord-333696-3ci9re9a 169 26 China China NNP cord-333696-3ci9re9a 169 27 . . . cord-333696-3ci9re9a 170 1 The the DT cord-333696-3ci9re9a 170 2 Lancet Lancet NNP cord-333696-3ci9re9a 170 3 Neurological Neurological NNP cord-333696-3ci9re9a 170 4 Manifestations manifestation NNS cord-333696-3ci9re9a 170 5 of of IN cord-333696-3ci9re9a 170 6 Hospitalized Hospitalized NNP cord-333696-3ci9re9a 170 7 Patients Patients NNPS cord-333696-3ci9re9a 170 8 with with IN cord-333696-3ci9re9a 170 9 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 170 10 in in IN cord-333696-3ci9re9a 170 11 Wuhan Wuhan NNP cord-333696-3ci9re9a 170 12 , , , cord-333696-3ci9re9a 170 13 China China NNP cord-333696-3ci9re9a 170 14 : : : cord-333696-3ci9re9a 170 15 a a DT cord-333696-3ci9re9a 170 16 retrospective retrospective JJ cord-333696-3ci9re9a 170 17 case case NN cord-333696-3ci9re9a 170 18 series series NN cord-333696-3ci9re9a 170 19 study study NN cord-333696-3ci9re9a 170 20 Cytokine cytokine NN cord-333696-3ci9re9a 170 21 determinants determinant NNS cord-333696-3ci9re9a 170 22 of of IN cord-333696-3ci9re9a 170 23 viral viral JJ cord-333696-3ci9re9a 170 24 tropism tropism NN cord-333696-3ci9re9a 170 25 SARS SARS NNP cord-333696-3ci9re9a 170 26 - - HYPH cord-333696-3ci9re9a 170 27 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 170 28 Cell Cell NNP cord-333696-3ci9re9a 170 29 Entry entry NN cord-333696-3ci9re9a 170 30 Depends depend VBZ cord-333696-3ci9re9a 170 31 on on IN cord-333696-3ci9re9a 170 32 ACE2 ACE2 NNP cord-333696-3ci9re9a 170 33 and and CC cord-333696-3ci9re9a 170 34 TMPRSS2 TMPRSS2 NNP cord-333696-3ci9re9a 170 35 and and CC cord-333696-3ci9re9a 170 36 Is be VBZ cord-333696-3ci9re9a 170 37 Blocked block VBN cord-333696-3ci9re9a 170 38 by by IN cord-333696-3ci9re9a 170 39 a a DT cord-333696-3ci9re9a 170 40 Clinically clinically RB cord-333696-3ci9re9a 170 41 Proven prove VBN cord-333696-3ci9re9a 170 42 Protease protease NN cord-333696-3ci9re9a 170 43 Inhibitor Inhibitor NNP cord-333696-3ci9re9a 170 44 Cryo Cryo NNP cord-333696-3ci9re9a 170 45 - - HYPH cord-333696-3ci9re9a 170 46 EM EM NNP cord-333696-3ci9re9a 170 47 structure structure NN cord-333696-3ci9re9a 170 48 of of IN cord-333696-3ci9re9a 170 49 the the DT cord-333696-3ci9re9a 170 50 2019-nCoV 2019-ncov CD cord-333696-3ci9re9a 170 51 spike spike NN cord-333696-3ci9re9a 170 52 in in IN cord-333696-3ci9re9a 170 53 the the DT cord-333696-3ci9re9a 170 54 prefusion prefusion NN cord-333696-3ci9re9a 170 55 conformation conformation NN cord-333696-3ci9re9a 170 56 Tissue tissue NN cord-333696-3ci9re9a 170 57 distribution distribution NN cord-333696-3ci9re9a 170 58 of of IN cord-333696-3ci9re9a 170 59 ACE2 ACE2 NNP cord-333696-3ci9re9a 170 60 protein protein NN cord-333696-3ci9re9a 170 61 , , , cord-333696-3ci9re9a 170 62 the the DT cord-333696-3ci9re9a 170 63 functional functional JJ cord-333696-3ci9re9a 170 64 receptor receptor NN cord-333696-3ci9re9a 170 65 for for IN cord-333696-3ci9re9a 170 66 SARS SARS NNP cord-333696-3ci9re9a 170 67 coronavirus coronavirus NN cord-333696-3ci9re9a 170 68 . . . cord-333696-3ci9re9a 171 1 A a DT cord-333696-3ci9re9a 171 2 first first JJ cord-333696-3ci9re9a 171 3 step step NN cord-333696-3ci9re9a 171 4 in in IN cord-333696-3ci9re9a 171 5 understanding understand VBG cord-333696-3ci9re9a 171 6 SARS SARS NNP cord-333696-3ci9re9a 171 7 pathogenesis pathogenesis NN cord-333696-3ci9re9a 171 8 Angiotensin Angiotensin NNP cord-333696-3ci9re9a 171 9 - - HYPH cord-333696-3ci9re9a 171 10 converting convert VBG cord-333696-3ci9re9a 171 11 enzyme enzyme NN cord-333696-3ci9re9a 171 12 2 2 CD cord-333696-3ci9re9a 171 13 : : : cord-333696-3ci9re9a 171 14 central central JJ cord-333696-3ci9re9a 171 15 regulator regulator NN cord-333696-3ci9re9a 171 16 for for IN cord-333696-3ci9re9a 171 17 cardiovascular cardiovascular JJ cord-333696-3ci9re9a 171 18 function function NN cord-333696-3ci9re9a 171 19 Dysregulation Dysregulation NNP cord-333696-3ci9re9a 171 20 of of IN cord-333696-3ci9re9a 171 21 immune immune JJ cord-333696-3ci9re9a 171 22 response response NN cord-333696-3ci9re9a 171 23 in in IN cord-333696-3ci9re9a 171 24 patients patient NNS cord-333696-3ci9re9a 171 25 with with IN cord-333696-3ci9re9a 171 26 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 171 27 in in IN cord-333696-3ci9re9a 171 28 Wuhan Wuhan NNP cord-333696-3ci9re9a 171 29 , , , cord-333696-3ci9re9a 171 30 China China NNP cord-333696-3ci9re9a 171 31 Advances advance VBZ cord-333696-3ci9re9a 171 32 in in IN cord-333696-3ci9re9a 171 33 the the DT cord-333696-3ci9re9a 171 34 research research NN cord-333696-3ci9re9a 171 35 of of IN cord-333696-3ci9re9a 171 36 cytokine cytokine NN cord-333696-3ci9re9a 171 37 storm storm NN cord-333696-3ci9re9a 171 38 mechanism mechanism NN cord-333696-3ci9re9a 171 39 induced induce VBN cord-333696-3ci9re9a 171 40 by by IN cord-333696-3ci9re9a 171 41 Corona Corona NNP cord-333696-3ci9re9a 171 42 Virus Virus NNP cord-333696-3ci9re9a 171 43 Disease Disease NNP cord-333696-3ci9re9a 171 44 Overriding override VBG cord-333696-3ci9re9a 171 45 the the DT cord-333696-3ci9re9a 171 46 brain brain NN cord-333696-3ci9re9a 171 47 's 's POS cord-333696-3ci9re9a 171 48 intrinsic intrinsic JJ cord-333696-3ci9re9a 171 49 resistance resistance NN cord-333696-3ci9re9a 171 50 to to IN cord-333696-3ci9re9a 171 51 leukocyte leukocyte NN cord-333696-3ci9re9a 171 52 recruitment recruitment NN cord-333696-3ci9re9a 171 53 with with IN cord-333696-3ci9re9a 171 54 intraparenchymal intraparenchymal JJ cord-333696-3ci9re9a 171 55 injections injection NNS cord-333696-3ci9re9a 171 56 of of IN cord-333696-3ci9re9a 171 57 recombinant recombinant JJ cord-333696-3ci9re9a 171 58 chemokines chemokine NNS cord-333696-3ci9re9a 171 59 IL-6 IL-6 NNP cord-333696-3ci9re9a 171 60 and and CC cord-333696-3ci9re9a 171 61 IL-8 IL-8 NNP cord-333696-3ci9re9a 171 62 production production NN cord-333696-3ci9re9a 171 63 from from IN cord-333696-3ci9re9a 171 64 cultured cultured JJ cord-333696-3ci9re9a 171 65 human human JJ cord-333696-3ci9re9a 171 66 endothelial endothelial JJ cord-333696-3ci9re9a 171 67 cells cell NNS cord-333696-3ci9re9a 171 68 stimulated stimulate VBN cord-333696-3ci9re9a 171 69 by by IN cord-333696-3ci9re9a 171 70 infection infection NN cord-333696-3ci9re9a 171 71 with with IN cord-333696-3ci9re9a 171 72 Rickettsia Rickettsia NNP cord-333696-3ci9re9a 171 73 conorii conorii NNP cord-333696-3ci9re9a 171 74 via via IN cord-333696-3ci9re9a 171 75 a a DT cord-333696-3ci9re9a 171 76 cell cell NN cord-333696-3ci9re9a 171 77 - - HYPH cord-333696-3ci9re9a 171 78 associated associate VBN cord-333696-3ci9re9a 171 79 IL-1 IL-1 NNP cord-333696-3ci9re9a 171 80 alpha alpha NN cord-333696-3ci9re9a 171 81 - - HYPH cord-333696-3ci9re9a 171 82 dependent dependent JJ cord-333696-3ci9re9a 171 83 pathway pathway NN cord-333696-3ci9re9a 171 84 Systemic systemic JJ cord-333696-3ci9re9a 171 85 inflammation inflammation NN cord-333696-3ci9re9a 171 86 and and CC cord-333696-3ci9re9a 171 87 the the DT cord-333696-3ci9re9a 171 88 brain brain NN cord-333696-3ci9re9a 171 89 : : : cord-333696-3ci9re9a 171 90 novel novel NN cord-333696-3ci9re9a 171 91 roles role NNS cord-333696-3ci9re9a 171 92 of of IN cord-333696-3ci9re9a 171 93 genetic genetic JJ cord-333696-3ci9re9a 171 94 , , , cord-333696-3ci9re9a 171 95 molecular molecular JJ cord-333696-3ci9re9a 171 96 , , , cord-333696-3ci9re9a 171 97 and and CC cord-333696-3ci9re9a 171 98 environmental environmental JJ cord-333696-3ci9re9a 171 99 cues cue NNS cord-333696-3ci9re9a 171 100 as as IN cord-333696-3ci9re9a 171 101 drivers driver NNS cord-333696-3ci9re9a 171 102 of of IN cord-333696-3ci9re9a 171 103 neurodegeneration neurodegeneration NN cord-333696-3ci9re9a 171 104 . . . cord-333696-3ci9re9a 172 1 Frontiers frontier NNS cord-333696-3ci9re9a 172 2 in in IN cord-333696-3ci9re9a 172 3 cellular cellular JJ cord-333696-3ci9re9a 172 4 neuroscience neuroscience NN cord-333696-3ci9re9a 173 1 Severe severe JJ cord-333696-3ci9re9a 173 2 acute acute JJ cord-333696-3ci9re9a 173 3 respiratory respiratory JJ cord-333696-3ci9re9a 173 4 syndrome syndrome NN cord-333696-3ci9re9a 173 5 coronavirus coronavirus NN cord-333696-3ci9re9a 173 6 infection infection NN cord-333696-3ci9re9a 173 7 causes cause VBZ cord-333696-3ci9re9a 173 8 neuronal neuronal JJ cord-333696-3ci9re9a 173 9 death death NN cord-333696-3ci9re9a 173 10 in in IN cord-333696-3ci9re9a 173 11 the the DT cord-333696-3ci9re9a 173 12 absence absence NN cord-333696-3ci9re9a 173 13 of of IN cord-333696-3ci9re9a 173 14 encephalitis encephalitis NN cord-333696-3ci9re9a 173 15 in in IN cord-333696-3ci9re9a 173 16 mice mouse NNS cord-333696-3ci9re9a 173 17 transgenic transgenic JJ cord-333696-3ci9re9a 173 18 for for IN cord-333696-3ci9re9a 174 1 human human JJ cord-333696-3ci9re9a 174 2 ACE2 ACE2 NNP cord-333696-3ci9re9a 174 3 Middle Middle NNP cord-333696-3ci9re9a 174 4 East East NNP cord-333696-3ci9re9a 174 5 Respiratory Respiratory NNP cord-333696-3ci9re9a 174 6 Syndrome Syndrome NNP cord-333696-3ci9re9a 174 7 Coronavirus Coronavirus NNP cord-333696-3ci9re9a 174 8 Causes cause VBZ cord-333696-3ci9re9a 174 9 Multiple Multiple NNP cord-333696-3ci9re9a 174 10 Organ Organ NNP cord-333696-3ci9re9a 174 11 Damage Damage NNP cord-333696-3ci9re9a 174 12 and and CC cord-333696-3ci9re9a 174 13 Lethal Lethal NNP cord-333696-3ci9re9a 174 14 Disease Disease NNP cord-333696-3ci9re9a 174 15 in in IN cord-333696-3ci9re9a 174 16 Mice Mice NNP cord-333696-3ci9re9a 174 17 Transgenic Transgenic NNP cord-333696-3ci9re9a 174 18 for for IN cord-333696-3ci9re9a 174 19 Human Human NNP cord-333696-3ci9re9a 174 20 Dipeptidyl Dipeptidyl NNP cord-333696-3ci9re9a 174 21 Peptidase Peptidase NNP cord-333696-3ci9re9a 174 22 4 4 CD cord-333696-3ci9re9a 174 23 Human human JJ cord-333696-3ci9re9a 174 24 respiratory respiratory JJ cord-333696-3ci9re9a 174 25 coronavirus coronavirus NN cord-333696-3ci9re9a 174 26 OC43 OC43 NNP cord-333696-3ci9re9a 174 27 : : : cord-333696-3ci9re9a 174 28 genetic genetic JJ cord-333696-3ci9re9a 174 29 stability stability NN cord-333696-3ci9re9a 174 30 and and CC cord-333696-3ci9re9a 174 31 neuroinvasion neuroinvasion NNP cord-333696-3ci9re9a 174 32 Effect effect NN cord-333696-3ci9re9a 174 33 of of IN cord-333696-3ci9re9a 174 34 olfactory olfactory JJ cord-333696-3ci9re9a 174 35 bulb bulb NN cord-333696-3ci9re9a 174 36 ablation ablation NN cord-333696-3ci9re9a 174 37 on on IN cord-333696-3ci9re9a 174 38 spread spread NN cord-333696-3ci9re9a 174 39 of of IN cord-333696-3ci9re9a 174 40 a a DT cord-333696-3ci9re9a 174 41 neurotropic neurotropic JJ cord-333696-3ci9re9a 174 42 coronavirus coronavirus NN cord-333696-3ci9re9a 174 43 into into IN cord-333696-3ci9re9a 174 44 the the DT cord-333696-3ci9re9a 174 45 mouse mouse NN cord-333696-3ci9re9a 174 46 brain brain NN cord-333696-3ci9re9a 174 47 . . . cord-333696-3ci9re9a 175 1 The the DT cord-333696-3ci9re9a 175 2 Journal Journal NNP cord-333696-3ci9re9a 175 3 of of IN cord-333696-3ci9re9a 175 4 experimental experimental JJ cord-333696-3ci9re9a 175 5 medicine medicine NN cord-333696-3ci9re9a 175 6 Management Management NNP cord-333696-3ci9re9a 175 7 of of IN cord-333696-3ci9re9a 175 8 corona corona NNP cord-333696-3ci9re9a 175 9 virus virus NNP cord-333696-3ci9re9a 175 10 disease-19 disease-19 NNP cord-333696-3ci9re9a 175 11 ( ( -LRB- cord-333696-3ci9re9a 175 12 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 175 13 ) ) -RRB- cord-333696-3ci9re9a 175 14 : : : cord-333696-3ci9re9a 175 15 the the DT cord-333696-3ci9re9a 175 16 Zhejiang Zhejiang NNP cord-333696-3ci9re9a 175 17 experience experience NN cord-333696-3ci9re9a 175 18 The the DT cord-333696-3ci9re9a 175 19 neuroinvasive neuroinvasive JJ cord-333696-3ci9re9a 175 20 potential potential NN cord-333696-3ci9re9a 175 21 of of IN cord-333696-3ci9re9a 175 22 SARS SARS NNP cord-333696-3ci9re9a 175 23 - - HYPH cord-333696-3ci9re9a 175 24 CoV2 CoV2 NNP cord-333696-3ci9re9a 175 25 may may MD cord-333696-3ci9re9a 175 26 play play VB cord-333696-3ci9re9a 175 27 a a DT cord-333696-3ci9re9a 175 28 role role NN cord-333696-3ci9re9a 175 29 in in IN cord-333696-3ci9re9a 175 30 the the DT cord-333696-3ci9re9a 175 31 respiratory respiratory JJ cord-333696-3ci9re9a 175 32 failure failure NN cord-333696-3ci9re9a 175 33 of of IN cord-333696-3ci9re9a 175 34 COVID-19 covid-19 JJ cord-333696-3ci9re9a 175 35 patients patient NNS cord-333696-3ci9re9a 175 36 Respiratory respiratory JJ cord-333696-3ci9re9a 175 37 failure failure NN cord-333696-3ci9re9a 175 38 alone alone RB cord-333696-3ci9re9a 175 39 does do VBZ cord-333696-3ci9re9a 175 40 not not RB cord-333696-3ci9re9a 175 41 suggest suggest VB cord-333696-3ci9re9a 175 42 central central JJ cord-333696-3ci9re9a 175 43 nervous nervous JJ cord-333696-3ci9re9a 175 44 system system NN cord-333696-3ci9re9a 175 45 invasion invasion NN cord-333696-3ci9re9a 175 46 by by IN cord-333696-3ci9re9a 175 47 SARS SARS NNP cord-333696-3ci9re9a 175 48 - - HYPH cord-333696-3ci9re9a 175 49 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 175 50 Clinical Clinical NNP cord-333696-3ci9re9a 175 51 Characteristics characteristic NNS cord-333696-3ci9re9a 175 52 of of IN cord-333696-3ci9re9a 175 53 Coronavirus Coronavirus NNP cord-333696-3ci9re9a 175 54 Disease Disease NNP cord-333696-3ci9re9a 175 55 2019 2019 CD cord-333696-3ci9re9a 175 56 in in IN cord-333696-3ci9re9a 175 57 China China NNP cord-333696-3ci9re9a 176 1 Is be VBZ cord-333696-3ci9re9a 176 2 nicotine nicotine NN cord-333696-3ci9re9a 176 3 exposure exposure NN cord-333696-3ci9re9a 176 4 linked link VBN cord-333696-3ci9re9a 176 5 to to IN cord-333696-3ci9re9a 176 6 cardiopulmonary cardiopulmonary JJ cord-333696-3ci9re9a 176 7 vulnerability vulnerability NN cord-333696-3ci9re9a 176 8 to to TO cord-333696-3ci9re9a 176 9 COVID-19 covid-19 VB cord-333696-3ci9re9a 176 10 in in IN cord-333696-3ci9re9a 176 11 the the DT cord-333696-3ci9re9a 176 12 general general JJ cord-333696-3ci9re9a 176 13 population population NN cord-333696-3ci9re9a 176 14 ? ? . cord-333696-3ci9re9a 177 1 Nicotine nicotine NN cord-333696-3ci9re9a 177 2 Modulates modulate VBZ cord-333696-3ci9re9a 177 3 the the DT cord-333696-3ci9re9a 177 4 Renin Renin NNP cord-333696-3ci9re9a 177 5 - - HYPH cord-333696-3ci9re9a 177 6 Angiotensin Angiotensin NNP cord-333696-3ci9re9a 177 7 System System NNP cord-333696-3ci9re9a 177 8 of of IN cord-333696-3ci9re9a 177 9 Cultured Cultured NNP cord-333696-3ci9re9a 177 10 Neurons Neurons NNPS cord-333696-3ci9re9a 177 11 and and CC cord-333696-3ci9re9a 177 12 Glial Glial NNP cord-333696-3ci9re9a 177 13 Cells cell NNS cord-333696-3ci9re9a 177 14 from from IN cord-333696-3ci9re9a 177 15 Cardiovascular Cardiovascular NNP cord-333696-3ci9re9a 177 16 Brain Brain NNP cord-333696-3ci9re9a 177 17 Areas Areas NNP cord-333696-3ci9re9a 177 18 of of IN cord-333696-3ci9re9a 177 19 Wistar Wistar NNP cord-333696-3ci9re9a 177 20 Kyoto Kyoto NNP cord-333696-3ci9re9a 177 21 and and CC cord-333696-3ci9re9a 177 22 Spontaneously spontaneously RB cord-333696-3ci9re9a 177 23 Hypertensive hypertensive JJ cord-333696-3ci9re9a 177 24 Rats Rats NNPS cord-333696-3ci9re9a 177 25 Nicotine Nicotine NNP cord-333696-3ci9re9a 177 26 and and CC cord-333696-3ci9re9a 177 27 the the DT cord-333696-3ci9re9a 177 28 renin renin NN cord-333696-3ci9re9a 177 29 - - HYPH cord-333696-3ci9re9a 177 30 angiotensin angiotensin NN cord-333696-3ci9re9a 177 31 system system NN cord-333696-3ci9re9a 177 32 Brain Brain NNP cord-333696-3ci9re9a 177 33 renin renin NN cord-333696-3ci9re9a 177 34 - - HYPH cord-333696-3ci9re9a 177 35 angiotensin angiotensin NN cord-333696-3ci9re9a 177 36 system system NN cord-333696-3ci9re9a 177 37 and and CC cord-333696-3ci9re9a 177 38 dopaminergic dopaminergic JJ cord-333696-3ci9re9a 177 39 cell cell NN cord-333696-3ci9re9a 177 40 vulnerability vulnerability NN cord-333696-3ci9re9a 177 41 Angiotensins Angiotensins NNP cord-333696-3ci9re9a 177 42 in in IN cord-333696-3ci9re9a 177 43 Alzheimer Alzheimer NNP cord-333696-3ci9re9a 177 44 's 's POS cord-333696-3ci9re9a 177 45 disease disease NN cord-333696-3ci9re9a 177 46 & & CC cord-333696-3ci9re9a 177 47 # # $ cord-333696-3ci9re9a 177 48 x2013 x2013 NN cord-333696-3ci9re9a 177 49 ; ; : cord-333696-3ci9re9a 177 50 friend friend NN cord-333696-3ci9re9a 177 51 or or CC cord-333696-3ci9re9a 177 52 foe foe NN cord-333696-3ci9re9a 177 53 ? ? . cord-333696-3ci9re9a 178 1 Trends trend NNS cord-333696-3ci9re9a 178 2 in in IN cord-333696-3ci9re9a 178 3 Neurosciences Neurosciences NNP cord-333696-3ci9re9a 178 4 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 178 5 and and CC cord-333696-3ci9re9a 178 6 SARS SARS NNP cord-333696-3ci9re9a 178 7 - - HYPH cord-333696-3ci9re9a 178 8 Cov-2 Cov-2 NNP cord-333696-3ci9re9a 178 9 Infection infection NN cord-333696-3ci9re9a 178 10 : : : cord-333696-3ci9re9a 178 11 Pathophysiology pathophysiology NN cord-333696-3ci9re9a 178 12 and and CC cord-333696-3ci9re9a 178 13 Clinical clinical JJ cord-333696-3ci9re9a 178 14 Effects effect NNS cord-333696-3ci9re9a 178 15 on on IN cord-333696-3ci9re9a 178 16 the the DT cord-333696-3ci9re9a 178 17 Nervous Nervous NNP cord-333696-3ci9re9a 178 18 System System NNP cord-333696-3ci9re9a 178 19 Neurological neurological JJ cord-333696-3ci9re9a 178 20 manifestations manifestation NNS cord-333696-3ci9re9a 178 21 of of IN cord-333696-3ci9re9a 178 22 COVID-19 covid-19 JJ cord-333696-3ci9re9a 178 23 and and CC cord-333696-3ci9re9a 178 24 other other JJ cord-333696-3ci9re9a 178 25 coronaviruses coronaviruse NNS cord-333696-3ci9re9a 178 26 : : : cord-333696-3ci9re9a 178 27 a a DT cord-333696-3ci9re9a 178 28 systematic systematic JJ cord-333696-3ci9re9a 178 29 review review NN cord-333696-3ci9re9a 178 30 Neurological neurological JJ cord-333696-3ci9re9a 178 31 implications implication NNS cord-333696-3ci9re9a 178 32 of of IN cord-333696-3ci9re9a 178 33 COVID-19 covid-19 JJ cord-333696-3ci9re9a 178 34 infections infection NNS cord-333696-3ci9re9a 178 35 Neurological neurological JJ cord-333696-3ci9re9a 178 36 manifestations manifestation NNS cord-333696-3ci9re9a 178 37 and and CC cord-333696-3ci9re9a 178 38 COVID-19 covid-19 NN cord-333696-3ci9re9a 178 39 : : : cord-333696-3ci9re9a 179 1 Experiences experience NNS cord-333696-3ci9re9a 179 2 from from IN cord-333696-3ci9re9a 179 3 a a DT cord-333696-3ci9re9a 179 4 tertiary tertiary JJ cord-333696-3ci9re9a 179 5 care care NN cord-333696-3ci9re9a 179 6 center center NN cord-333696-3ci9re9a 179 7 at at IN cord-333696-3ci9re9a 179 8 the the DT cord-333696-3ci9re9a 179 9 Frontline Frontline NNP cord-333696-3ci9re9a 179 10 Clinical Clinical NNP cord-333696-3ci9re9a 179 11 Characteristics Characteristics NNPS cord-333696-3ci9re9a 179 12 of of IN cord-333696-3ci9re9a 179 13 138 138 CD cord-333696-3ci9re9a 179 14 Hospitalized hospitalize VBN cord-333696-3ci9re9a 179 15 Patients patient NNS cord-333696-3ci9re9a 179 16 With with IN cord-333696-3ci9re9a 179 17 2019 2019 CD cord-333696-3ci9re9a 179 18 Novel Novel NNP cord-333696-3ci9re9a 179 19 Coronavirus Coronavirus NNP cord-333696-3ci9re9a 179 20 - - HYPH cord-333696-3ci9re9a 179 21 Infected infect VBN cord-333696-3ci9re9a 179 22 Pneumonia Pneumonia NNP cord-333696-3ci9re9a 179 23 in in IN cord-333696-3ci9re9a 179 24 Transverse transverse JJ cord-333696-3ci9re9a 179 25 myelitis myelitis NN cord-333696-3ci9re9a 179 26 - - : cord-333696-3ci9re9a 179 27 a a DT cord-333696-3ci9re9a 179 28 review review NN cord-333696-3ci9re9a 179 29 of of IN cord-333696-3ci9re9a 179 30 the the DT cord-333696-3ci9re9a 179 31 presentation presentation NN cord-333696-3ci9re9a 179 32 , , , cord-333696-3ci9re9a 179 33 diagnosis diagnosis NN cord-333696-3ci9re9a 179 34 , , , cord-333696-3ci9re9a 179 35 and and CC cord-333696-3ci9re9a 179 36 initial initial JJ cord-333696-3ci9re9a 179 37 management management NN cord-333696-3ci9re9a 179 38 . . . cord-333696-3ci9re9a 180 1 Discovery discovery NN cord-333696-3ci9re9a 180 2 medicine medicine NN cord-333696-3ci9re9a 181 1 An an DT cord-333696-3ci9re9a 181 2 approach approach NN cord-333696-3ci9re9a 181 3 to to IN cord-333696-3ci9re9a 181 4 the the DT cord-333696-3ci9re9a 181 5 diagnosis diagnosis NN cord-333696-3ci9re9a 181 6 of of IN cord-333696-3ci9re9a 181 7 acute acute JJ cord-333696-3ci9re9a 181 8 transverse transverse JJ cord-333696-3ci9re9a 181 9 myelitis myelitis NNP cord-333696-3ci9re9a 181 10 Acute acute JJ cord-333696-3ci9re9a 181 11 myelitis myelitis NNP cord-333696-3ci9re9a 181 12 after after IN cord-333696-3ci9re9a 181 13 SARS SARS NNP cord-333696-3ci9re9a 181 14 - - HYPH cord-333696-3ci9re9a 181 15 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 181 16 infection infection NN cord-333696-3ci9re9a 181 17 : : : cord-333696-3ci9re9a 181 18 a a DT cord-333696-3ci9re9a 181 19 case case NN cord-333696-3ci9re9a 181 20 report report NN cord-333696-3ci9re9a 181 21 . . . cord-333696-3ci9re9a 182 1 medRxiv medRxiv NNS cord-333696-3ci9re9a 182 2 Acute acute JJ cord-333696-3ci9re9a 182 3 transverse transverse JJ cord-333696-3ci9re9a 182 4 myelitis myelitis NN cord-333696-3ci9re9a 182 5 after after IN cord-333696-3ci9re9a 182 6 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 182 7 pneumonia pneumonia NN cord-333696-3ci9re9a 182 8 Magnetic Magnetic NNP cord-333696-3ci9re9a 182 9 resonance resonance NN cord-333696-3ci9re9a 182 10 imaging imaging NN cord-333696-3ci9re9a 182 11 findings finding NNS cord-333696-3ci9re9a 182 12 in in IN cord-333696-3ci9re9a 182 13 22 22 CD cord-333696-3ci9re9a 182 14 cases case NNS cord-333696-3ci9re9a 182 15 of of IN cord-333696-3ci9re9a 182 16 myelitis myelitis NNP cord-333696-3ci9re9a 182 17 : : : cord-333696-3ci9re9a 182 18 comparison comparison NN cord-333696-3ci9re9a 182 19 between between IN cord-333696-3ci9re9a 182 20 patients patient NNS cord-333696-3ci9re9a 182 21 with with IN cord-333696-3ci9re9a 182 22 and and CC cord-333696-3ci9re9a 182 23 without without IN cord-333696-3ci9re9a 182 24 multiple multiple JJ cord-333696-3ci9re9a 182 25 sclerosis sclerosis NN cord-333696-3ci9re9a 182 26 Viral viral JJ cord-333696-3ci9re9a 182 27 encephalitis encephalitis NN cord-333696-3ci9re9a 182 28 Viral viral JJ cord-333696-3ci9re9a 182 29 meningitis meningitis NN cord-333696-3ci9re9a 182 30 Herpes Herpes NNP cord-333696-3ci9re9a 182 31 Simplex Simplex NNP cord-333696-3ci9re9a 182 32 Virus-1 virus-1 NN cord-333696-3ci9re9a 182 33 Encephalitis Encephalitis NNP cord-333696-3ci9re9a 182 34 in in IN cord-333696-3ci9re9a 182 35 Adults Adults NNPS cord-333696-3ci9re9a 182 36 : : : cord-333696-3ci9re9a 182 37 Pathophysiology pathophysiology NN cord-333696-3ci9re9a 182 38 , , , cord-333696-3ci9re9a 182 39 Diagnosis Diagnosis NNP cord-333696-3ci9re9a 182 40 , , , cord-333696-3ci9re9a 182 41 and and CC cord-333696-3ci9re9a 182 42 Management Management NNP cord-333696-3ci9re9a 182 43 . . . cord-333696-3ci9re9a 183 1 Neurotherapeutics neurotherapeutic NNS cord-333696-3ci9re9a 184 1 A a DT cord-333696-3ci9re9a 184 2 first first JJ cord-333696-3ci9re9a 184 3 Case case NN cord-333696-3ci9re9a 184 4 of of IN cord-333696-3ci9re9a 184 5 Meningitis Meningitis NNP cord-333696-3ci9re9a 184 6 / / SYM cord-333696-3ci9re9a 184 7 Encephalitis Encephalitis NNP cord-333696-3ci9re9a 184 8 associated associate VBN cord-333696-3ci9re9a 184 9 with with IN cord-333696-3ci9re9a 184 10 SARS SARS NNP cord-333696-3ci9re9a 184 11 - - HYPH cord-333696-3ci9re9a 184 12 Coronavirus-2 Coronavirus-2 NNP cord-333696-3ci9re9a 184 13 COVID-19-associated covid-19-associate VBN cord-333696-3ci9re9a 184 14 encephalitis encephalitis RB cord-333696-3ci9re9a 184 15 mimicking mimic VBG cord-333696-3ci9re9a 184 16 glial glial JJ cord-333696-3ci9re9a 184 17 tumor tumor NN cord-333696-3ci9re9a 184 18 : : : cord-333696-3ci9re9a 184 19 a a DT cord-333696-3ci9re9a 184 20 case case NN cord-333696-3ci9re9a 184 21 report report NN cord-333696-3ci9re9a 184 22 Proton Proton NNP cord-333696-3ci9re9a 184 23 MR MR NNP cord-333696-3ci9re9a 184 24 spectroscopy spectroscopy NN cord-333696-3ci9re9a 184 25 in in IN cord-333696-3ci9re9a 184 26 the the DT cord-333696-3ci9re9a 184 27 diagnosis diagnosis NN cord-333696-3ci9re9a 184 28 and and CC cord-333696-3ci9re9a 184 29 differentiation differentiation NN cord-333696-3ci9re9a 184 30 of of IN cord-333696-3ci9re9a 184 31 encephalitis encephalitis RB cord-333696-3ci9re9a 184 32 from from IN cord-333696-3ci9re9a 184 33 other other JJ cord-333696-3ci9re9a 184 34 mimicking mimic VBG cord-333696-3ci9re9a 184 35 lesions lesion NNS cord-333696-3ci9re9a 185 1 COVID-19-associated covid-19-associated JJ cord-333696-3ci9re9a 185 2 mild mild JJ cord-333696-3ci9re9a 185 3 encephalitis encephalitis RB cord-333696-3ci9re9a 185 4 / / , cord-333696-3ci9re9a 185 5 encephalopathy encephalopathy NN cord-333696-3ci9re9a 185 6 with with IN cord-333696-3ci9re9a 185 7 a a DT cord-333696-3ci9re9a 185 8 reversible reversible JJ cord-333696-3ci9re9a 185 9 splenial splenial JJ cord-333696-3ci9re9a 185 10 lesion lesion NN cord-333696-3ci9re9a 185 11 Epidemiology epidemiology NN cord-333696-3ci9re9a 185 12 of of IN cord-333696-3ci9re9a 185 13 acute acute JJ cord-333696-3ci9re9a 185 14 encephalopathy encephalopathy NN cord-333696-3ci9re9a 185 15 in in IN cord-333696-3ci9re9a 185 16 Japan Japan NNP cord-333696-3ci9re9a 185 17 , , , cord-333696-3ci9re9a 185 18 with with IN cord-333696-3ci9re9a 185 19 emphasis emphasis NN cord-333696-3ci9re9a 185 20 on on IN cord-333696-3ci9re9a 185 21 the the DT cord-333696-3ci9re9a 185 22 association association NN cord-333696-3ci9re9a 185 23 of of IN cord-333696-3ci9re9a 185 24 viruses virus NNS cord-333696-3ci9re9a 185 25 and and CC cord-333696-3ci9re9a 185 26 syndromes syndrome NNS cord-333696-3ci9re9a 185 27 . . . cord-333696-3ci9re9a 186 1 Brain Brain NNP cord-333696-3ci9re9a 186 2 and and CC cord-333696-3ci9re9a 186 3 Development Development NNP cord-333696-3ci9re9a 186 4 Clinically clinically RB cord-333696-3ci9re9a 186 5 mild mild JJ cord-333696-3ci9re9a 186 6 encephalitis encephaliti NNS cord-333696-3ci9re9a 186 7 / / , cord-333696-3ci9re9a 186 8 encephalopathy encephalopathy NN cord-333696-3ci9re9a 186 9 with with IN cord-333696-3ci9re9a 186 10 a a DT cord-333696-3ci9re9a 186 11 reversible reversible JJ cord-333696-3ci9re9a 186 12 splenial splenial JJ cord-333696-3ci9re9a 186 13 lesion lesion NN cord-333696-3ci9re9a 186 14 Mycoplasma Mycoplasma NNP cord-333696-3ci9re9a 186 15 pneumoniae pneumoniae NN cord-333696-3ci9re9a 186 16 - - HYPH cord-333696-3ci9re9a 186 17 associated associate VBN cord-333696-3ci9re9a 186 18 mild mild JJ cord-333696-3ci9re9a 186 19 encephalitis encephalitis NN cord-333696-3ci9re9a 186 20 / / , cord-333696-3ci9re9a 186 21 encephalopathy encephalopathy NN cord-333696-3ci9re9a 186 22 with with IN cord-333696-3ci9re9a 186 23 a a DT cord-333696-3ci9re9a 186 24 reversible reversible JJ cord-333696-3ci9re9a 186 25 splenial splenial JJ cord-333696-3ci9re9a 186 26 lesion lesion NN cord-333696-3ci9re9a 186 27 : : : cord-333696-3ci9re9a 186 28 report report NN cord-333696-3ci9re9a 186 29 of of IN cord-333696-3ci9re9a 186 30 two two CD cord-333696-3ci9re9a 186 31 pediatric pediatric JJ cord-333696-3ci9re9a 186 32 cases case NNS cord-333696-3ci9re9a 186 33 and and CC cord-333696-3ci9re9a 186 34 a a DT cord-333696-3ci9re9a 186 35 comprehensive comprehensive JJ cord-333696-3ci9re9a 186 36 literature literature NN cord-333696-3ci9re9a 186 37 review review NN cord-333696-3ci9re9a 186 38 Clinical clinical JJ cord-333696-3ci9re9a 186 39 implications implication NNS cord-333696-3ci9re9a 186 40 of of IN cord-333696-3ci9re9a 186 41 splenium splenium NN cord-333696-3ci9re9a 186 42 magnetic magnetic JJ cord-333696-3ci9re9a 186 43 resonance resonance NN cord-333696-3ci9re9a 186 44 imaging imaging NN cord-333696-3ci9re9a 186 45 signal signal NN cord-333696-3ci9re9a 186 46 changes change NNS cord-333696-3ci9re9a 186 47 Acute acute JJ cord-333696-3ci9re9a 186 48 encephalopathy encephalopathy NN cord-333696-3ci9re9a 186 49 associated associate VBN cord-333696-3ci9re9a 186 50 with with IN cord-333696-3ci9re9a 186 51 influenza influenza NN cord-333696-3ci9re9a 186 52 and and CC cord-333696-3ci9re9a 186 53 other other JJ cord-333696-3ci9re9a 186 54 viral viral JJ cord-333696-3ci9re9a 186 55 infections infection NNS cord-333696-3ci9re9a 186 56 Septic septic JJ cord-333696-3ci9re9a 186 57 encephalopathy encephalopathy NN cord-333696-3ci9re9a 186 58 and and CC cord-333696-3ci9re9a 186 59 septic septic JJ cord-333696-3ci9re9a 186 60 encephalitis encephalitis NN cord-333696-3ci9re9a 186 61 Encephalopathy encephalopathy NN cord-333696-3ci9re9a 186 62 of of IN cord-333696-3ci9re9a 186 63 Infection Infection NNP cord-333696-3ci9re9a 186 64 and and CC cord-333696-3ci9re9a 186 65 Systemic Systemic NNP cord-333696-3ci9re9a 186 66 Inflammation inflammation NN cord-333696-3ci9re9a 187 1 The the DT cord-333696-3ci9re9a 187 2 origin origin NN cord-333696-3ci9re9a 187 3 , , , cord-333696-3ci9re9a 187 4 transmission transmission NN cord-333696-3ci9re9a 187 5 and and CC cord-333696-3ci9re9a 187 6 clinical clinical JJ cord-333696-3ci9re9a 187 7 therapies therapy NNS cord-333696-3ci9re9a 187 8 on on IN cord-333696-3ci9re9a 187 9 coronavirus coronavirus NN cord-333696-3ci9re9a 187 10 disease disease NN cord-333696-3ci9re9a 187 11 2019 2019 CD cord-333696-3ci9re9a 188 1 ( ( -LRB- cord-333696-3ci9re9a 188 2 COVID-19 covid-19 VB cord-333696-3ci9re9a 188 3 ) ) -RRB- cord-333696-3ci9re9a 188 4 outbreak outbreak NN cord-333696-3ci9re9a 188 5 -an -an CD cord-333696-3ci9re9a 188 6 update update NN cord-333696-3ci9re9a 188 7 on on IN cord-333696-3ci9re9a 188 8 the the DT cord-333696-3ci9re9a 188 9 status status NN cord-333696-3ci9re9a 188 10 Pathological pathological JJ cord-333696-3ci9re9a 188 11 findings finding NNS cord-333696-3ci9re9a 188 12 of of IN cord-333696-3ci9re9a 188 13 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 188 14 associated associate VBN cord-333696-3ci9re9a 188 15 with with IN cord-333696-3ci9re9a 188 16 acute acute JJ cord-333696-3ci9re9a 188 17 respiratory respiratory JJ cord-333696-3ci9re9a 188 18 distress distress NN cord-333696-3ci9re9a 188 19 syndrome syndrome NN cord-333696-3ci9re9a 188 20 . . . cord-333696-3ci9re9a 189 1 The the DT cord-333696-3ci9re9a 189 2 Lancet Lancet NNP cord-333696-3ci9re9a 189 3 Respiratory Respiratory NNP cord-333696-3ci9re9a 189 4 Medicine medicine NN cord-333696-3ci9re9a 189 5 Acute acute NN cord-333696-3ci9re9a 189 6 necrotizing necrotize VBG cord-333696-3ci9re9a 189 7 encephalopathy encephalopathy NN cord-333696-3ci9re9a 189 8 of of IN cord-333696-3ci9re9a 189 9 childhood childhood NN cord-333696-3ci9re9a 189 10 : : : cord-333696-3ci9re9a 189 11 correlation correlation NN cord-333696-3ci9re9a 189 12 of of IN cord-333696-3ci9re9a 189 13 MR MR NNP cord-333696-3ci9re9a 189 14 findings finding NNS cord-333696-3ci9re9a 189 15 and and CC cord-333696-3ci9re9a 189 16 clinical clinical JJ cord-333696-3ci9re9a 189 17 outcome outcome NN cord-333696-3ci9re9a 190 1 Imaging imaging NN cord-333696-3ci9re9a 190 2 of of IN cord-333696-3ci9re9a 190 3 acute acute JJ cord-333696-3ci9re9a 190 4 disseminated disseminate VBN cord-333696-3ci9re9a 190 5 encephalomyelitis encephalomyelitis NN cord-333696-3ci9re9a 190 6 . . . cord-333696-3ci9re9a 191 1 Neuroimaging neuroimaging NN cord-333696-3ci9re9a 191 2 clinics clinic NNS cord-333696-3ci9re9a 191 3 of of IN cord-333696-3ci9re9a 191 4 North North NNP cord-333696-3ci9re9a 191 5 America America NNP cord-333696-3ci9re9a 192 1 COVID-19 covid-19 VB cord-333696-3ci9re9a 192 2 : : : cord-333696-3ci9re9a 192 3 consider consider VB cord-333696-3ci9re9a 192 4 cytokine cytokine JJ cord-333696-3ci9re9a 192 5 storm storm NN cord-333696-3ci9re9a 192 6 syndromes syndrome NNS cord-333696-3ci9re9a 192 7 and and CC cord-333696-3ci9re9a 192 8 immunosuppression immunosuppression NN cord-333696-3ci9re9a 192 9 . . . cord-333696-3ci9re9a 193 1 The the DT cord-333696-3ci9re9a 193 2 Lancet Lancet NNP cord-333696-3ci9re9a 193 3 COVID-19-associated covid-19-associate VBN cord-333696-3ci9re9a 193 4 Acute acute JJ cord-333696-3ci9re9a 193 5 Hemorrhagic Hemorrhagic NNP cord-333696-3ci9re9a 193 6 Necrotizing Necrotizing NNP cord-333696-3ci9re9a 193 7 Encephalopathy encephalopathy NN cord-333696-3ci9re9a 193 8 : : : cord-333696-3ci9re9a 193 9 CT CT NNP cord-333696-3ci9re9a 193 10 and and CC cord-333696-3ci9re9a 193 11 MRI MRI NNP cord-333696-3ci9re9a 193 12 Features feature NNS cord-333696-3ci9re9a 194 1 COVID-19-related covid-19-related JJ cord-333696-3ci9re9a 194 2 acute acute JJ cord-333696-3ci9re9a 194 3 necrotizing necrotize VBG cord-333696-3ci9re9a 194 4 encephalopathy encephalopathy NN cord-333696-3ci9re9a 194 5 with with IN cord-333696-3ci9re9a 194 6 brain brain NN cord-333696-3ci9re9a 194 7 stem stem NN cord-333696-3ci9re9a 194 8 involvement involvement NN cord-333696-3ci9re9a 194 9 in in IN cord-333696-3ci9re9a 194 10 a a DT cord-333696-3ci9re9a 194 11 patient patient NN cord-333696-3ci9re9a 194 12 with with IN cord-333696-3ci9re9a 194 13 aplastic aplastic JJ cord-333696-3ci9re9a 194 14 anemia anemia NN cord-333696-3ci9re9a 194 15 Leukodystrophies Leukodystrophies NNP cord-333696-3ci9re9a 194 16 : : : cord-333696-3ci9re9a 194 17 clinical clinical JJ cord-333696-3ci9re9a 194 18 and and CC cord-333696-3ci9re9a 194 19 genetic genetic JJ cord-333696-3ci9re9a 194 20 aspects aspect NNS cord-333696-3ci9re9a 195 1 COVID-19-associated COVID-19-associated NNP cord-333696-3ci9re9a 195 2 delayed delay VBN cord-333696-3ci9re9a 195 3 posthypoxic posthypoxic NN cord-333696-3ci9re9a 195 4 leukoencephalopathy leukoencephalopathy NNP cord-333696-3ci9re9a 196 1 Leukoencephalopathy Leukoencephalopathy NNP cord-333696-3ci9re9a 196 2 Associated Associated NNP cord-333696-3ci9re9a 196 3 with with IN cord-333696-3ci9re9a 196 4 Severe severe JJ cord-333696-3ci9re9a 196 5 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 196 6 Infection infection NN cord-333696-3ci9re9a 196 7 : : : cord-333696-3ci9re9a 196 8 Sequela Sequela NNP cord-333696-3ci9re9a 196 9 of of IN cord-333696-3ci9re9a 196 10 Hypoxemia Hypoxemia NNP cord-333696-3ci9re9a 196 11 ? ? . cord-333696-3ci9re9a 197 1 COVID-19-associated COVID-19-associated NNP cord-333696-3ci9re9a 197 2 Diffuse Diffuse NNP cord-333696-3ci9re9a 197 3 Leukoencephalopathy Leukoencephalopathy NNP cord-333696-3ci9re9a 197 4 and and CC cord-333696-3ci9re9a 197 5 Microhemorrhages Microhemorrhages NNP cord-333696-3ci9re9a 197 6 Acute Acute NNP cord-333696-3ci9re9a 197 7 disseminated disseminate VBD cord-333696-3ci9re9a 197 8 encephalomyelitis encephalomyelitis NN cord-333696-3ci9re9a 197 9 Detection detection NN cord-333696-3ci9re9a 197 10 of of IN cord-333696-3ci9re9a 197 11 coronavirus coronavirus NN cord-333696-3ci9re9a 197 12 in in IN cord-333696-3ci9re9a 197 13 the the DT cord-333696-3ci9re9a 197 14 central central JJ cord-333696-3ci9re9a 197 15 nervous nervous JJ cord-333696-3ci9re9a 197 16 system system NN cord-333696-3ci9re9a 197 17 of of IN cord-333696-3ci9re9a 197 18 a a DT cord-333696-3ci9re9a 197 19 child child NN cord-333696-3ci9re9a 197 20 with with IN cord-333696-3ci9re9a 197 21 acute acute JJ cord-333696-3ci9re9a 197 22 disseminated disseminate VBN cord-333696-3ci9re9a 197 23 encephalomyelitis encephalomyelitis NN cord-333696-3ci9re9a 198 1 The the DT cord-333696-3ci9re9a 198 2 species specie NNS cord-333696-3ci9re9a 198 3 Severe severe JJ cord-333696-3ci9re9a 198 4 acute acute JJ cord-333696-3ci9re9a 198 5 respiratory respiratory JJ cord-333696-3ci9re9a 198 6 syndrome syndrome NN cord-333696-3ci9re9a 198 7 - - HYPH cord-333696-3ci9re9a 198 8 related relate VBN cord-333696-3ci9re9a 198 9 coronavirus coronavirus NN cord-333696-3ci9re9a 198 10 : : : cord-333696-3ci9re9a 198 11 classifying classify VBG cord-333696-3ci9re9a 198 12 2019-nCoV 2019-ncov CD cord-333696-3ci9re9a 198 13 and and CC cord-333696-3ci9re9a 198 14 naming name VBG cord-333696-3ci9re9a 198 15 it -PRON- PRP cord-333696-3ci9re9a 199 1 SARS SARS NNP cord-333696-3ci9re9a 199 2 - - HYPH cord-333696-3ci9re9a 199 3 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 200 1 Why why WRB cord-333696-3ci9re9a 200 2 now now RB cord-333696-3ci9re9a 200 3 ? ? . cord-333696-3ci9re9a 201 1 Moving move VBG cord-333696-3ci9re9a 201 2 from from IN cord-333696-3ci9re9a 201 3 stroke stroke NN cord-333696-3ci9re9a 201 4 risk risk NN cord-333696-3ci9re9a 201 5 factors factor NNS cord-333696-3ci9re9a 201 6 to to IN cord-333696-3ci9re9a 201 7 stroke stroke VB cord-333696-3ci9re9a 201 8 triggers trigger NNS cord-333696-3ci9re9a 201 9 . . . cord-333696-3ci9re9a 202 1 Current current JJ cord-333696-3ci9re9a 202 2 Opinion opinion NN cord-333696-3ci9re9a 202 3 in in IN cord-333696-3ci9re9a 202 4 Neurology Neurology NNP cord-333696-3ci9re9a 202 5 Laboratory Laboratory NNP cord-333696-3ci9re9a 202 6 - - HYPH cord-333696-3ci9re9a 202 7 confirmed confirm VBN cord-333696-3ci9re9a 202 8 respiratory respiratory JJ cord-333696-3ci9re9a 202 9 infections infection NNS cord-333696-3ci9re9a 202 10 as as IN cord-333696-3ci9re9a 202 11 triggers trigger NNS cord-333696-3ci9re9a 202 12 for for IN cord-333696-3ci9re9a 202 13 acute acute JJ cord-333696-3ci9re9a 202 14 myocardial myocardial JJ cord-333696-3ci9re9a 202 15 infarction infarction NN cord-333696-3ci9re9a 202 16 and and CC cord-333696-3ci9re9a 202 17 stroke stroke NN cord-333696-3ci9re9a 202 18 : : : cord-333696-3ci9re9a 202 19 a a DT cord-333696-3ci9re9a 202 20 self self NN cord-333696-3ci9re9a 202 21 - - HYPH cord-333696-3ci9re9a 202 22 controlled control VBN cord-333696-3ci9re9a 202 23 case case NN cord-333696-3ci9re9a 202 24 series series NN cord-333696-3ci9re9a 202 25 analysis analysis NN cord-333696-3ci9re9a 202 26 of of IN cord-333696-3ci9re9a 202 27 national national JJ cord-333696-3ci9re9a 202 28 linked link VBN cord-333696-3ci9re9a 202 29 datasets dataset NNS cord-333696-3ci9re9a 202 30 from from IN cord-333696-3ci9re9a 202 31 Scotland Scotland NNP cord-333696-3ci9re9a 202 32 Influenza Influenza NNP cord-333696-3ci9re9a 202 33 Virus Virus NNP cord-333696-3ci9re9a 202 34 Infection infection NN cord-333696-3ci9re9a 202 35 Aggravates aggravate VBZ cord-333696-3ci9re9a 202 36 Stroke stroke NN cord-333696-3ci9re9a 202 37 Outcome outcome NN cord-333696-3ci9re9a 202 38 . . . cord-333696-3ci9re9a 203 1 Stroke stroke JJ cord-333696-3ci9re9a 203 2 Acute acute JJ cord-333696-3ci9re9a 203 3 cerebrovascular cerebrovascular JJ cord-333696-3ci9re9a 203 4 disease disease NN cord-333696-3ci9re9a 203 5 following follow VBG cord-333696-3ci9re9a 203 6 COVID-19 covid-19 VB cord-333696-3ci9re9a 203 7 : : : cord-333696-3ci9re9a 203 8 a a DT cord-333696-3ci9re9a 203 9 single single JJ cord-333696-3ci9re9a 203 10 center center NN cord-333696-3ci9re9a 203 11 , , , cord-333696-3ci9re9a 203 12 retrospective retrospective JJ cord-333696-3ci9re9a 203 13 , , , cord-333696-3ci9re9a 203 14 observational observational JJ cord-333696-3ci9re9a 203 15 study study NN cord-333696-3ci9re9a 203 16 Analysis Analysis NNP cord-333696-3ci9re9a 203 17 of of IN cord-333696-3ci9re9a 203 18 Risk Risk NNP cord-333696-3ci9re9a 203 19 Factors Factors NNPS cord-333696-3ci9re9a 203 20 for for IN cord-333696-3ci9re9a 203 21 the the DT cord-333696-3ci9re9a 203 22 Thromboembolic Thromboembolic NNP cord-333696-3ci9re9a 203 23 Events Events NNPS cord-333696-3ci9re9a 203 24 from from IN cord-333696-3ci9re9a 203 25 88 88 CD cord-333696-3ci9re9a 203 26 Patients patient NNS cord-333696-3ci9re9a 203 27 with with IN cord-333696-3ci9re9a 203 28 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 203 29 Pneumonia Pneumonia NNP cord-333696-3ci9re9a 203 30 in in IN cord-333696-3ci9re9a 203 31 Wuhan Wuhan NNP cord-333696-3ci9re9a 203 32 , , , cord-333696-3ci9re9a 203 33 China China NNP cord-333696-3ci9re9a 203 34 : : : cord-333696-3ci9re9a 203 35 A a DT cord-333696-3ci9re9a 203 36 Retrospective Retrospective NNP cord-333696-3ci9re9a 203 37 Report report NN cord-333696-3ci9re9a 204 1 Prominent prominent JJ cord-333696-3ci9re9a 204 2 changes change NNS cord-333696-3ci9re9a 204 3 in in IN cord-333696-3ci9re9a 204 4 blood blood NN cord-333696-3ci9re9a 204 5 coagulation coagulation NN cord-333696-3ci9re9a 204 6 of of IN cord-333696-3ci9re9a 204 7 patients patient NNS cord-333696-3ci9re9a 204 8 with with IN cord-333696-3ci9re9a 204 9 SARS SARS NNP cord-333696-3ci9re9a 204 10 - - HYPH cord-333696-3ci9re9a 204 11 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 204 12 infection infection NN cord-333696-3ci9re9a 204 13 Coagulopathy Coagulopathy NNP cord-333696-3ci9re9a 204 14 and and CC cord-333696-3ci9re9a 204 15 antiphospholipid antiphospholipid NNP cord-333696-3ci9re9a 204 16 antibodies antibody NNS cord-333696-3ci9re9a 204 17 in in IN cord-333696-3ci9re9a 204 18 patients patient NNS cord-333696-3ci9re9a 204 19 with with IN cord-333696-3ci9re9a 204 20 Covid-19 Covid-19 NNP cord-333696-3ci9re9a 204 21 Cerebral Cerebral NNP cord-333696-3ci9re9a 204 22 Venous Venous NNP cord-333696-3ci9re9a 204 23 Thrombosis Thrombosis NNP cord-333696-3ci9re9a 204 24 Associated Associated NNP cord-333696-3ci9re9a 204 25 with with IN cord-333696-3ci9re9a 204 26 COVID-19 COVID-19 NNP cord-333696-3ci9re9a 204 27 SARS2-CoV-2 SARS2-CoV-2 NNP cord-333696-3ci9re9a 204 28 and and CC cord-333696-3ci9re9a 204 29 stroke stroke NN cord-333696-3ci9re9a 204 30 in in IN cord-333696-3ci9re9a 204 31 a a DT cord-333696-3ci9re9a 204 32 New New NNP cord-333696-3ci9re9a 204 33 York York NNP cord-333696-3ci9re9a 204 34 healthcare healthcare NN cord-333696-3ci9re9a 204 35 system system NN cord-333696-3ci9re9a 205 1 Severe severe JJ cord-333696-3ci9re9a 205 2 acute acute JJ cord-333696-3ci9re9a 205 3 respiratory respiratory JJ cord-333696-3ci9re9a 205 4 syndrome syndrome NN cord-333696-3ci9re9a 205 5 coronavirus coronavirus NN cord-333696-3ci9re9a 205 6 2 2 CD cord-333696-3ci9re9a 205 7 infection infection NN cord-333696-3ci9re9a 205 8 and and CC cord-333696-3ci9re9a 205 9 ischemic ischemic JJ cord-333696-3ci9re9a 205 10 stroke stroke NN cord-333696-3ci9re9a 205 11 Neurologic neurologic NN cord-333696-3ci9re9a 205 12 Features Features NNPS cord-333696-3ci9re9a 205 13 in in IN cord-333696-3ci9re9a 205 14 Severe severe JJ cord-333696-3ci9re9a 205 15 SARS SARS NNP cord-333696-3ci9re9a 205 16 - - HYPH cord-333696-3ci9re9a 205 17 CoV-2 CoV-2 NNP cord-333696-3ci9re9a 205 18 Infection Infection NNP cord-333696-3ci9re9a 205 19 Neurological neurological JJ cord-333696-3ci9re9a 205 20 complications complication NNS cord-333696-3ci9re9a 205 21 of of IN cord-333696-3ci9re9a 205 22 coronavirus coronavirus NN cord-333696-3ci9re9a 205 23 disease disease NN cord-333696-3ci9re9a 205 24 ( ( -LRB- cord-333696-3ci9re9a 205 25 covid-19 covid-19 NNP cord-333696-3ci9re9a 205 26 ) ) -RRB- cord-333696-3ci9re9a 205 27 : : : cord-333696-3ci9re9a 205 28 encephalopathy encephalopathy NN cord-333696-3ci9re9a 205 29 . . . cord-333696-3ci9re9a 206 1 Cureus Cureus NNP cord-333696-3ci9re9a 206 2 None None NNP cord-333696-3ci9re9a 206 3 . . .