id	sid	tid	token	lemma	pos
cord-312486-rumqopg0	1	1	key	key	JJ
cord-312486-rumqopg0	1	2	:	:	:
cord-312486-rumqopg0	1	3	cord-312486-rumqopg0	cord-312486-rumqopg0	NNS
cord-312486-rumqopg0	1	4	authors	author	NNS
cord-312486-rumqopg0	1	5	:	:	:
cord-312486-rumqopg0	1	6	Jacob	Jacob	NNP
cord-312486-rumqopg0	1	7	,	,	,
cord-312486-rumqopg0	1	8	Chaim	Chaim	NNP
cord-312486-rumqopg0	1	9	Oscar	Oscar	NNP
cord-312486-rumqopg0	1	10	title	title	NN
cord-312486-rumqopg0	1	11	:	:	:
cord-312486-rumqopg0	1	12	On	on	IN
cord-312486-rumqopg0	1	13	the	the	DT
cord-312486-rumqopg0	1	14	genetics	genetic	NNS
cord-312486-rumqopg0	1	15	and	and	CC
cord-312486-rumqopg0	1	16	immunopathogenesis	immunopathogenesis	NNP
cord-312486-rumqopg0	1	17	of	of	IN
cord-312486-rumqopg0	1	18	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	1	19	date	date	NN
cord-312486-rumqopg0	1	20	:	:	:
cord-312486-rumqopg0	1	21	2020	2020	CD
cord-312486-rumqopg0	1	22	-	-	HYPH
cord-312486-rumqopg0	1	23	09	09	CD
cord-312486-rumqopg0	1	24	-	-	SYM
cord-312486-rumqopg0	1	25	10	10	CD
cord-312486-rumqopg0	1	26	journal	journal	NN
cord-312486-rumqopg0	1	27	:	:	:
cord-312486-rumqopg0	2	1	Clin	Clin	NNP
cord-312486-rumqopg0	2	2	Immunol	Immunol	NNP
cord-312486-rumqopg0	2	3	DOI	DOI	NNP
cord-312486-rumqopg0	2	4	:	:	:
cord-312486-rumqopg0	2	5	10.1016	10.1016	CD
cord-312486-rumqopg0	2	6	/	/	SYM
cord-312486-rumqopg0	2	7	j.clim.2020.108591	j.clim.2020.108591	NNP
cord-312486-rumqopg0	2	8	sha	sha	NNP
cord-312486-rumqopg0	2	9	:	:	:
cord-312486-rumqopg0	2	10	8ba9da79967dca248be3286ff6ee36c8af5803ad	8ba9da79967dca248be3286ff6ee36c8af5803ad	CD
cord-312486-rumqopg0	2	11	doc_id	doc_id	CD
cord-312486-rumqopg0	2	12	:	:	:
cord-312486-rumqopg0	2	13	312486	312486	CD
cord-312486-rumqopg0	2	14	cord_uid	cord_uid	NNS
cord-312486-rumqopg0	2	15	:	:	:
cord-312486-rumqopg0	2	16	rumqopg0	rumqopg0	NN
cord-312486-rumqopg0	2	17	Most	most	RBS
cord-312486-rumqopg0	2	18	severe	severe	JJ
cord-312486-rumqopg0	2	19	cases	case	NNS
cord-312486-rumqopg0	2	20	with	with	IN
cord-312486-rumqopg0	2	21	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	2	22	,	,	,
cord-312486-rumqopg0	2	23	especially	especially	RB
cord-312486-rumqopg0	2	24	those	those	DT
cord-312486-rumqopg0	2	25	with	with	IN
cord-312486-rumqopg0	2	26	pulmonary	pulmonary	JJ
cord-312486-rumqopg0	2	27	failure	failure	NN
cord-312486-rumqopg0	2	28	,	,	,
cord-312486-rumqopg0	2	29	are	be	VBP
cord-312486-rumqopg0	2	30	not	not	RB
cord-312486-rumqopg0	2	31	a	a	DT
cord-312486-rumqopg0	2	32	consequence	consequence	NN
cord-312486-rumqopg0	2	33	of	of	IN
cord-312486-rumqopg0	2	34	viral	viral	JJ
cord-312486-rumqopg0	2	35	burden	burden	NN
cord-312486-rumqopg0	3	1	and/or	and/or	CC
cord-312486-rumqopg0	3	2	failure	failure	NN
cord-312486-rumqopg0	3	3	of	of	IN
cord-312486-rumqopg0	3	4	the	the	DT
cord-312486-rumqopg0	3	5	‘	'	``
cord-312486-rumqopg0	3	6	adaptive	adaptive	JJ
cord-312486-rumqopg0	3	7	’	'	''
cord-312486-rumqopg0	3	8	immune	immune	JJ
cord-312486-rumqopg0	3	9	response	response	NN
cord-312486-rumqopg0	3	10	to	to	TO
cord-312486-rumqopg0	3	11	subdue	subdue	VB
cord-312486-rumqopg0	3	12	the	the	DT
cord-312486-rumqopg0	3	13	pathogen	pathogen	NN
cord-312486-rumqopg0	3	14	by	by	IN
cord-312486-rumqopg0	3	15	utilizing	utilize	VBG
cord-312486-rumqopg0	3	16	an	an	DT
cord-312486-rumqopg0	3	17	adequate	adequate	JJ
cord-312486-rumqopg0	3	18	‘	'	``
cord-312486-rumqopg0	3	19	adaptive	adaptive	JJ
cord-312486-rumqopg0	3	20	’	'	''
cord-312486-rumqopg0	3	21	immune	immune	JJ
cord-312486-rumqopg0	3	22	defense	defense	NN
cord-312486-rumqopg0	3	23	.	.	.
cord-312486-rumqopg0	4	1	Rather	rather	RB
cord-312486-rumqopg0	4	2	it	-PRON-	PRP
cord-312486-rumqopg0	4	3	is	be	VBZ
cord-312486-rumqopg0	4	4	a	a	DT
cord-312486-rumqopg0	4	5	consequence	consequence	NN
cord-312486-rumqopg0	4	6	of	of	IN
cord-312486-rumqopg0	4	7	immunopathology	immunopathology	NN
cord-312486-rumqopg0	4	8	,	,	,
cord-312486-rumqopg0	4	9	resulting	result	VBG
cord-312486-rumqopg0	4	10	from	from	IN
cord-312486-rumqopg0	4	11	imbalanced	imbalanced	JJ
cord-312486-rumqopg0	4	12	innate	innate	JJ
cord-312486-rumqopg0	4	13	immune	immune	JJ
cord-312486-rumqopg0	4	14	response	response	NN
cord-312486-rumqopg0	4	15	,	,	,
cord-312486-rumqopg0	4	16	which	which	WDT
cord-312486-rumqopg0	4	17	may	may	MD
cord-312486-rumqopg0	4	18	not	not	RB
cord-312486-rumqopg0	4	19	be	be	VB
cord-312486-rumqopg0	4	20	linked	link	VBN
cord-312486-rumqopg0	4	21	to	to	IN
cord-312486-rumqopg0	4	22	pathogen	pathogen	NN
cord-312486-rumqopg0	4	23	burden	burden	NN
cord-312486-rumqopg0	4	24	at	at	RB
cord-312486-rumqopg0	4	25	all	all	RB
cord-312486-rumqopg0	4	26	.	.	.
cord-312486-rumqopg0	5	1	In	in	IN
cord-312486-rumqopg0	5	2	fact	fact	NN
cord-312486-rumqopg0	5	3	,	,	,
cord-312486-rumqopg0	5	4	it	-PRON-	PRP
cord-312486-rumqopg0	5	5	might	may	MD
cord-312486-rumqopg0	5	6	be	be	VB
cord-312486-rumqopg0	5	7	described	describe	VBN
cord-312486-rumqopg0	5	8	as	as	IN
cord-312486-rumqopg0	5	9	an	an	DT
cord-312486-rumqopg0	5	10	autoinflammatory	autoinflammatory	JJ
cord-312486-rumqopg0	5	11	disease	disease	NN
cord-312486-rumqopg0	5	12	.	.	.
cord-312486-rumqopg0	6	1	The	the	DT
cord-312486-rumqopg0	6	2	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	6	3	-	-	HYPH
cord-312486-rumqopg0	6	4	like	like	JJ
cord-312486-rumqopg0	6	5	disease	disease	NN
cord-312486-rumqopg0	6	6	seen	see	VBN
cord-312486-rumqopg0	6	7	in	in	IN
cord-312486-rumqopg0	6	8	children	child	NNS
cord-312486-rumqopg0	6	9	with	with	IN
cord-312486-rumqopg0	6	10	SARS	SARS	NNP
cord-312486-rumqopg0	6	11	-	-	HYPH
cord-312486-rumqopg0	6	12	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	6	13	exposure	exposure	NN
cord-312486-rumqopg0	6	14	might	may	MD
cord-312486-rumqopg0	6	15	be	be	VB
cord-312486-rumqopg0	6	16	another	another	DT
cord-312486-rumqopg0	6	17	example	example	NN
cord-312486-rumqopg0	6	18	of	of	IN
cord-312486-rumqopg0	6	19	similar	similar	JJ
cord-312486-rumqopg0	6	20	mechanism	mechanism	NN
cord-312486-rumqopg0	6	21	.	.	.
cord-312486-rumqopg0	7	1	replicate	replicate	VB
cord-312486-rumqopg0	7	2	both	both	DT
cord-312486-rumqopg0	7	3	in	in	IN
cord-312486-rumqopg0	7	4	the	the	DT
cord-312486-rumqopg0	7	5	upper	upper	JJ
cord-312486-rumqopg0	7	6	and	and	CC
cord-312486-rumqopg0	7	7	lower	low	JJR
cord-312486-rumqopg0	7	8	respiratory	respiratory	JJ
cord-312486-rumqopg0	7	9	tract	tract	NN
cord-312486-rumqopg0	7	10	might	may	MD
cord-312486-rumqopg0	7	11	explain	explain	VB
cord-312486-rumqopg0	7	12	why	why	WRB
cord-312486-rumqopg0	7	13	people	people	NNS
cord-312486-rumqopg0	7	14	infected	infect	VBN
cord-312486-rumqopg0	7	15	have	have	VBP
cord-312486-rumqopg0	7	16	such	such	JJ
cord-312486-rumqopg0	7	17	different	different	JJ
cord-312486-rumqopg0	7	18	experiences	experience	NNS
cord-312486-rumqopg0	7	19	.	.	.
cord-312486-rumqopg0	8	1	The	the	DT
cord-312486-rumqopg0	8	2	virus	virus	NN
cord-312486-rumqopg0	8	3	can	can	MD
cord-312486-rumqopg0	8	4	start	start	VB
cord-312486-rumqopg0	8	5	in	in	IN
cord-312486-rumqopg0	8	6	the	the	DT
cord-312486-rumqopg0	8	7	throat	throat	NN
cord-312486-rumqopg0	8	8	or	or	CC
cord-312486-rumqopg0	8	9	nose	nose	NN
cord-312486-rumqopg0	8	10	,	,	,
cord-312486-rumqopg0	8	11	producing	produce	VBG
cord-312486-rumqopg0	8	12	a	a	DT
cord-312486-rumqopg0	8	13	cough	cough	NN
cord-312486-rumqopg0	8	14	,	,	,
cord-312486-rumqopg0	8	15	disrupting	disrupt	VBG
cord-312486-rumqopg0	8	16	taste	taste	NN
cord-312486-rumqopg0	8	17	and	and	CC
cord-312486-rumqopg0	8	18	smell	smell	NN
cord-312486-rumqopg0	8	19	,	,	,
cord-312486-rumqopg0	8	20	and	and	CC
cord-312486-rumqopg0	8	21	then	then	RB
cord-312486-rumqopg0	8	22	end	end	VB
cord-312486-rumqopg0	8	23	there	there	RB
cord-312486-rumqopg0	8	24	.	.	.
cord-312486-rumqopg0	9	1	Or	or	CC
cord-312486-rumqopg0	9	2	it	-PRON-	PRP
cord-312486-rumqopg0	9	3	might	may	MD
cord-312486-rumqopg0	9	4	work	work	VB
cord-312486-rumqopg0	9	5	its	-PRON-	PRP$
cord-312486-rumqopg0	9	6	way	way	NN
cord-312486-rumqopg0	9	7	down	down	IN
cord-312486-rumqopg0	9	8	to	to	IN
cord-312486-rumqopg0	9	9	the	the	DT
cord-312486-rumqopg0	9	10	lungs	lung	NNS
cord-312486-rumqopg0	9	11	and	and	CC
cord-312486-rumqopg0	9	12	debilitate	debilitate	VB
cord-312486-rumqopg0	9	13	that	that	DT
cord-312486-rumqopg0	9	14	organ	organ	NN
cord-312486-rumqopg0	9	15	and	and	CC
cord-312486-rumqopg0	9	16	the	the	DT
cord-312486-rumqopg0	9	17	entire	entire	JJ
cord-312486-rumqopg0	9	18	organism	organism	NN
cord-312486-rumqopg0	9	19	.	.	.
cord-312486-rumqopg0	10	1	It	-PRON-	PRP
cord-312486-rumqopg0	10	2	is	be	VBZ
cord-312486-rumqopg0	10	3	quite	quite	RB
cord-312486-rumqopg0	10	4	likely	likely	JJ
cord-312486-rumqopg0	10	5	that	that	IN
cord-312486-rumqopg0	10	6	once	once	RB
cord-312486-rumqopg0	10	7	SARS	SARS	NNP
cord-312486-rumqopg0	10	8	-	-	HYPH
cord-312486-rumqopg0	10	9	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	10	10	gets	get	VBZ
cord-312486-rumqopg0	10	11	down	down	RP
cord-312486-rumqopg0	10	12	in	in	IN
cord-312486-rumqopg0	10	13	the	the	DT
cord-312486-rumqopg0	10	14	lungs	lung	NNS
cord-312486-rumqopg0	10	15	,	,	,
cord-312486-rumqopg0	10	16	it	-PRON-	PRP
cord-312486-rumqopg0	10	17	's	be	VBZ
cord-312486-rumqopg0	10	18	probably	probably	RB
cord-312486-rumqopg0	10	19	just	just	RB
cord-312486-rumqopg0	10	20	as	as	RB
cord-312486-rumqopg0	10	21	deadly	deadly	JJ
cord-312486-rumqopg0	10	22	as	as	IN
cord-312486-rumqopg0	10	23	SARS	SARS	NNP
cord-312486-rumqopg0	10	24	-	-	HYPH
cord-312486-rumqopg0	10	25	CoV-1	CoV-1	NNP
cord-312486-rumqopg0	10	26	.	.	.
cord-312486-rumqopg0	11	1	In	in	IN
cord-312486-rumqopg0	11	2	sum	sum	NN
cord-312486-rumqopg0	11	3	,	,	,
cord-312486-rumqopg0	11	4	the	the	DT
cord-312486-rumqopg0	11	5	assessment	assessment	NN
cord-312486-rumqopg0	11	6	expressed	express	VBN
cord-312486-rumqopg0	11	7	in	in	IN
cord-312486-rumqopg0	11	8	the	the	DT
cord-312486-rumqopg0	11	9	general	general	JJ
cord-312486-rumqopg0	11	10	media	medium	NNS
cord-312486-rumqopg0	11	11	,	,	,
cord-312486-rumqopg0	11	12	but	but	CC
cord-312486-rumqopg0	11	13	sometimes	sometimes	RB
cord-312486-rumqopg0	11	14	also	also	RB
cord-312486-rumqopg0	11	15	in	in	IN
cord-312486-rumqopg0	11	16	professional	professional	JJ
cord-312486-rumqopg0	11	17	literature	literature	NN
cord-312486-rumqopg0	11	18	[	[	-LRB-
cord-312486-rumqopg0	11	19	26	26	CD
cord-312486-rumqopg0	11	20	]	]	-RRB-
cord-312486-rumqopg0	11	21	[	[	-LRB-
cord-312486-rumqopg0	11	22	27	27	CD
cord-312486-rumqopg0	11	23	]	]	-RRB-
cord-312486-rumqopg0	11	24	[	[	-LRB-
cord-312486-rumqopg0	11	25	28	28	CD
cord-312486-rumqopg0	11	26	]	]	-RRB-
cord-312486-rumqopg0	11	27	[	[	-LRB-
cord-312486-rumqopg0	11	28	29	29	CD
cord-312486-rumqopg0	11	29	]	]	-RRB-
cord-312486-rumqopg0	11	30	that	that	IN
cord-312486-rumqopg0	11	31	the	the	DT
cord-312486-rumqopg0	11	32	virus	virus	NN
cord-312486-rumqopg0	11	33	is	be	VBZ
cord-312486-rumqopg0	11	34	entirely	entirely	RB
cord-312486-rumqopg0	11	35	-new‖	-new‖	ADD
cord-312486-rumqopg0	11	36	and	and	CC
cord-312486-rumqopg0	11	37	that	that	IN
cord-312486-rumqopg0	11	38	the	the	DT
cord-312486-rumqopg0	11	39	immune	immune	JJ
cord-312486-rumqopg0	11	40	system	system	NN
cord-312486-rumqopg0	11	41	is	be	VBZ
cord-312486-rumqopg0	11	42	-naive‖	-naive‖	VBN
cord-312486-rumqopg0	11	43	namely	namely	RB
cord-312486-rumqopg0	11	44	that	that	IN
cord-312486-rumqopg0	11	45	it	-PRON-	PRP
cord-312486-rumqopg0	11	46	is	be	VBZ
cord-312486-rumqopg0	11	47	totally	totally	RB
cord-312486-rumqopg0	11	48	inexperienced	inexperienced	JJ
cord-312486-rumqopg0	11	49	when	when	WRB
cord-312486-rumqopg0	11	50	it	-PRON-	PRP
cord-312486-rumqopg0	11	51	comes	come	VBZ
cord-312486-rumqopg0	11	52	to	to	IN
cord-312486-rumqopg0	11	53	this	this	DT
cord-312486-rumqopg0	11	54	virus	virus	NN
cord-312486-rumqopg0	11	55	is	be	VBZ
cord-312486-rumqopg0	11	56	exaggerated	exaggerated	JJ
cord-312486-rumqopg0	11	57	.	.	.
cord-312486-rumqopg0	12	1	A	a	DT
cord-312486-rumqopg0	12	2	more	more	RBR
cord-312486-rumqopg0	12	3	accurate	accurate	JJ
cord-312486-rumqopg0	12	4	description	description	NN
cord-312486-rumqopg0	12	5	of	of	IN
cord-312486-rumqopg0	12	6	this	this	DT
cord-312486-rumqopg0	12	7	virus	virus	NN
cord-312486-rumqopg0	12	8	would	would	MD
cord-312486-rumqopg0	12	9	be	be	VB
cord-312486-rumqopg0	12	10	a	a	DT
cord-312486-rumqopg0	12	11	reemergence	reemergence	NN
cord-312486-rumqopg0	12	12	of	of	IN
cord-312486-rumqopg0	12	13	a	a	DT
cord-312486-rumqopg0	12	14	known	know	VBN
cord-312486-rumqopg0	12	15	foe	foe	NN
cord-312486-rumqopg0	12	16	that	that	WDT
cord-312486-rumqopg0	12	17	has	have	VBZ
cord-312486-rumqopg0	12	18	a	a	DT
cord-312486-rumqopg0	12	19	somewhat	somewhat	RB
cord-312486-rumqopg0	12	20	more	more	RBR
cord-312486-rumqopg0	12	21	optimal	optimal	JJ
cord-312486-rumqopg0	12	22	organization	organization	NN
cord-312486-rumqopg0	12	23	of	of	IN
cord-312486-rumqopg0	12	24	its	-PRON-	PRP$
cord-312486-rumqopg0	12	25	resources	resource	NNS
cord-312486-rumqopg0	12	26	making	make	VBG
cord-312486-rumqopg0	12	27	it	-PRON-	PRP
cord-312486-rumqopg0	12	28	more	more	RBR
cord-312486-rumqopg0	12	29	suitable	suitable	JJ
cord-312486-rumqopg0	12	30	to	to	TO
cord-312486-rumqopg0	12	31	become	become	VB
cord-312486-rumqopg0	12	32	a	a	DT
cord-312486-rumqopg0	12	33	pandemic	pandemic	JJ
cord-312486-rumqopg0	12	34	pathogen	pathogen	NN
cord-312486-rumqopg0	12	35	.	.	.
cord-312486-rumqopg0	13	1	The	the	DT
cord-312486-rumqopg0	13	2	genetic	genetic	JJ
cord-312486-rumqopg0	13	3	sequence	sequence	NN
cord-312486-rumqopg0	13	4	diversity	diversity	NN
cord-312486-rumqopg0	13	5	of	of	IN
cord-312486-rumqopg0	13	6	SARS	SARS	NNP
cord-312486-rumqopg0	13	7	-	-	HYPH
cord-312486-rumqopg0	13	8	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	13	9	is	be	VBZ
cord-312486-rumqopg0	13	10	low	low	JJ
cord-312486-rumqopg0	13	11	.	.	.
cord-312486-rumqopg0	14	1	As	as	IN
cord-312486-rumqopg0	14	2	a	a	DT
cord-312486-rumqopg0	14	3	consequence	consequence	NN
cord-312486-rumqopg0	14	4	of	of	IN
cord-312486-rumqopg0	14	5	a	a	DT
cord-312486-rumqopg0	14	6	massive	massive	JJ
cord-312486-rumqopg0	14	7	effort	effort	NN
cord-312486-rumqopg0	14	8	to	to	TO
cord-312486-rumqopg0	14	9	sequence	sequence	VB
cord-312486-rumqopg0	14	10	viral	viral	JJ
cord-312486-rumqopg0	14	11	samples	sample	NNS
cord-312486-rumqopg0	14	12	obtained	obtain	VBN
cord-312486-rumqopg0	14	13	from	from	IN
cord-312486-rumqopg0	14	14	humans	human	NNS
cord-312486-rumqopg0	14	15	infected	infect	VBN
cord-312486-rumqopg0	14	16	all	all	RB
cord-312486-rumqopg0	14	17	around	around	IN
cord-312486-rumqopg0	14	18	the	the	DT
cord-312486-rumqopg0	14	19	world	world	NN
cord-312486-rumqopg0	14	20	,	,	,
cord-312486-rumqopg0	14	21	there	there	EX
cord-312486-rumqopg0	14	22	are	be	VBP
cord-312486-rumqopg0	14	23	now	now	RB
cord-312486-rumqopg0	14	24	thousands	thousand	NNS
cord-312486-rumqopg0	14	25	of	of	IN
cord-312486-rumqopg0	14	26	viral	viral	JJ
cord-312486-rumqopg0	14	27	sequences	sequence	NNS
cord-312486-rumqopg0	14	28	available	available	JJ
cord-312486-rumqopg0	14	29	which	which	WDT
cord-312486-rumqopg0	14	30	permits	permit	VBZ
cord-312486-rumqopg0	14	31	an	an	DT
cord-312486-rumqopg0	14	32	unprecedented	unprecedented	JJ
cord-312486-rumqopg0	14	33	and	and	CC
cord-312486-rumqopg0	14	34	detailed	detailed	JJ
cord-312486-rumqopg0	14	35	analysis	analysis	NN
cord-312486-rumqopg0	14	36	of	of	IN
cord-312486-rumqopg0	14	37	the	the	DT
cord-312486-rumqopg0	14	38	virus	virus	NN
cord-312486-rumqopg0	14	39	's	's	POS
cord-312486-rumqopg0	14	40	genetic	genetic	JJ
cord-312486-rumqopg0	14	41	evolution	evolution	NN
cord-312486-rumqopg0	14	42	.	.	.
cord-312486-rumqopg0	15	1	During	during	IN
cord-312486-rumqopg0	15	2	the	the	DT
cord-312486-rumqopg0	15	3	early	early	JJ
cord-312486-rumqopg0	15	4	phase	phase	NN
cord-312486-rumqopg0	15	5	of	of	IN
cord-312486-rumqopg0	15	6	the	the	DT
cord-312486-rumqopg0	15	7	outbreak	outbreak	NN
cord-312486-rumqopg0	15	8	in	in	IN
cord-312486-rumqopg0	15	9	Wuhan	Wuhan	NNP
cord-312486-rumqopg0	15	10	two	two	CD
cord-312486-rumqopg0	15	11	major	major	JJ
cord-312486-rumqopg0	15	12	lineages	lineage	NNS
cord-312486-rumqopg0	15	13	of	of	IN
cord-312486-rumqopg0	15	14	SARS	SARS	NNP
cord-312486-rumqopg0	15	15	-	-	HYPH
cord-312486-rumqopg0	15	16	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	15	17	,	,	,
cord-312486-rumqopg0	15	18	with	with	IN
cord-312486-rumqopg0	15	19	different	different	JJ
cord-312486-rumqopg0	15	20	exposure	exposure	NN
cord-312486-rumqopg0	15	21	histories	history	NNS
cord-312486-rumqopg0	15	22	,	,	,
cord-312486-rumqopg0	15	23	were	be	VBD
cord-312486-rumqopg0	15	24	categorized	categorize	VBN
cord-312486-rumqopg0	15	25	as	as	IN
cord-312486-rumqopg0	15	26	L	L	NNP
cord-312486-rumqopg0	15	27	(	(	-LRB-
cord-312486-rumqopg0	15	28	∼70	∼70	NNP
cord-312486-rumqopg0	15	29	%	%	NN
cord-312486-rumqopg0	15	30	of	of	IN
cord-312486-rumqopg0	15	31	sequences	sequence	NNS
cord-312486-rumqopg0	15	32	)	)	-RRB-
cord-312486-rumqopg0	15	33	and	and	CC
cord-312486-rumqopg0	15	34	S	S	NNP
cord-312486-rumqopg0	15	35	(	(	-LRB-
cord-312486-rumqopg0	15	36	∼30	∼30	NNP
cord-312486-rumqopg0	15	37	%	%	NN
cord-312486-rumqopg0	15	38	)	)	-RRB-
cord-312486-rumqopg0	15	39	based	base	VBN
cord-312486-rumqopg0	15	40	on	on	IN
cord-312486-rumqopg0	15	41	two	two	CD
cord-312486-rumqopg0	15	42	tightly	tightly	RB
cord-312486-rumqopg0	15	43	linked	link	VBN
cord-312486-rumqopg0	15	44	single	single	JJ
cord-312486-rumqopg0	15	45	nucleotide	nucleotide	JJ
cord-312486-rumqopg0	15	46	polymorphism	polymorphism	NN
cord-312486-rumqopg0	15	47	(	(	-LRB-
cord-312486-rumqopg0	15	48	SNP)s	SNP)s	NNP
cord-312486-rumqopg0	15	49	-	-	:
cord-312486-rumqopg0	15	50	a	a	DT
cord-312486-rumqopg0	15	51	synonymous	synonymous	JJ
cord-312486-rumqopg0	15	52	mutation	mutation	NN
cord-312486-rumqopg0	15	53	in	in	IN
cord-312486-rumqopg0	15	54	the	the	DT
cord-312486-rumqopg0	15	55	ORF1ab	ORF1ab	NNP
cord-312486-rumqopg0	15	56	of	of	IN
cord-312486-rumqopg0	15	57	the	the	DT
cord-312486-rumqopg0	15	58	genome	genome	NN
cord-312486-rumqopg0	15	59	,	,	,
cord-312486-rumqopg0	15	60	and	and	CC
cord-312486-rumqopg0	15	61	a	a	DT
cord-312486-rumqopg0	15	62	non	non	JJ
cord-312486-rumqopg0	15	63	-	-	JJ
cord-312486-rumqopg0	15	64	synonymous	synonymous	JJ
cord-312486-rumqopg0	15	65	S84L	s84l	NN
cord-312486-rumqopg0	15	66	amino	amino	NN
cord-312486-rumqopg0	15	67	acid	acid	NN
cord-312486-rumqopg0	15	68	change	change	NN
cord-312486-rumqopg0	15	69	in	in	IN
cord-312486-rumqopg0	15	70	ORF8	ORF8	NNP
cord-312486-rumqopg0	15	71	.	.	.
cord-312486-rumqopg0	16	1	[	[	-LRB-
cord-312486-rumqopg0	16	2	30	30	CD
cord-312486-rumqopg0	16	3	]	]	-RRB-
cord-312486-rumqopg0	16	4	.	.	.
cord-312486-rumqopg0	17	1	The	the	DT
cord-312486-rumqopg0	17	2	S	S	NNP
cord-312486-rumqopg0	17	3	variant	variant	NN
cord-312486-rumqopg0	17	4	was	be	VBD
cord-312486-rumqopg0	17	5	evolutionarily	evolutionarily	RB
cord-312486-rumqopg0	17	6	more	more	RBR
cord-312486-rumqopg0	17	7	related	related	JJ
cord-312486-rumqopg0	17	8	to	to	IN
cord-312486-rumqopg0	17	9	animal	animal	NN
cord-312486-rumqopg0	18	1	CoV.	CoV.	NNP
cord-312486-rumqopg0	19	1	The	the	DT
cord-312486-rumqopg0	19	2	functional	functional	JJ
cord-312486-rumqopg0	19	3	consequences	consequence	NNS
cord-312486-rumqopg0	19	4	of	of	IN
cord-312486-rumqopg0	19	5	the	the	DT
cord-312486-rumqopg0	19	6	S84L	S84L	NNP
cord-312486-rumqopg0	19	7	mutation	mutation	NN
cord-312486-rumqopg0	19	8	are	be	VBP
cord-312486-rumqopg0	19	9	not	not	RB
cord-312486-rumqopg0	19	10	known	know	VBN
cord-312486-rumqopg0	19	11	.	.	.
cord-312486-rumqopg0	20	1	Nevertheless	nevertheless	RB
cord-312486-rumqopg0	20	2	,	,	,
cord-312486-rumqopg0	20	3	the	the	DT
cord-312486-rumqopg0	20	4	two	two	CD
cord-312486-rumqopg0	20	5	variants	variant	NNS
cord-312486-rumqopg0	20	6	exhibited	exhibit	VBD
cord-312486-rumqopg0	20	7	similar	similar	JJ
cord-312486-rumqopg0	20	8	virulence	virulence	NN
cord-312486-rumqopg0	20	9	and	and	CC
cord-312486-rumqopg0	20	10	clinical	clinical	JJ
cord-312486-rumqopg0	20	11	outcome	outcome	NN
cord-312486-rumqopg0	20	12	[	[	-LRB-
cord-312486-rumqopg0	20	13	31	31	CD
cord-312486-rumqopg0	20	14	]	]	-RRB-
cord-312486-rumqopg0	20	15	.	.	.
cord-312486-rumqopg0	21	1	A	a	DT
cord-312486-rumqopg0	21	2	mutation	mutation	NN
cord-312486-rumqopg0	21	3	in	in	IN
cord-312486-rumqopg0	21	4	the	the	DT
cord-312486-rumqopg0	21	5	spike	spike	NN
cord-312486-rumqopg0	21	6	protein	protein	NN
cord-312486-rumqopg0	21	7	-	-	:
cord-312486-rumqopg0	21	8	that	that	WDT
cord-312486-rumqopg0	21	9	mediates	mediate	VBZ
cord-312486-rumqopg0	21	10	SARS	SARS	NNP
cord-312486-rumqopg0	21	11	-	-	HYPH
cord-312486-rumqopg0	21	12	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	21	13	entry	entry	NN
cord-312486-rumqopg0	21	14	into	into	IN
cord-312486-rumqopg0	21	15	host	host	NN
cord-312486-rumqopg0	21	16	cells	cell	NNS
cord-312486-rumqopg0	21	17	and	and	CC
cord-312486-rumqopg0	21	18	potentially	potentially	RB
cord-312486-rumqopg0	21	19	of	of	IN
cord-312486-rumqopg0	21	20	functional	functional	JJ
cord-312486-rumqopg0	21	21	importance	importance	NN
cord-312486-rumqopg0	21	22	-	-	,
cord-312486-rumqopg0	21	23	was	be	VBD
cord-312486-rumqopg0	21	24	described	describe	VBN
cord-312486-rumqopg0	21	25	by	by	IN
cord-312486-rumqopg0	21	26	several	several	JJ
cord-312486-rumqopg0	21	27	teams	team	NNS
cord-312486-rumqopg0	21	28	of	of	IN
cord-312486-rumqopg0	21	29	researchers	researcher	NNS
cord-312486-rumqopg0	21	30	[	[	-LRB-
cord-312486-rumqopg0	21	31	32	32	CD
cord-312486-rumqopg0	21	32	]	]	-RRB-
cord-312486-rumqopg0	21	33	[	[	-LRB-
cord-312486-rumqopg0	21	34	33	33	CD
cord-312486-rumqopg0	21	35	]	]	-RRB-
cord-312486-rumqopg0	21	36	[	[	-LRB-
cord-312486-rumqopg0	21	37	34	34	CD
cord-312486-rumqopg0	21	38	]	]	-RRB-
cord-312486-rumqopg0	21	39	[	[	-LRB-
cord-312486-rumqopg0	21	40	35	35	CD
cord-312486-rumqopg0	21	41	]	]	-RRB-
cord-312486-rumqopg0	21	42	.	.	.
cord-312486-rumqopg0	22	1	The	the	DT
cord-312486-rumqopg0	22	2	D614	d614	NN
cord-312486-rumqopg0	22	3	G	g	NN
cord-312486-rumqopg0	22	4	mutation	mutation	NN
cord-312486-rumqopg0	22	5	at	at	IN
cord-312486-rumqopg0	22	6	residue	residue	NN
cord-312486-rumqopg0	22	7	614	614	CD
cord-312486-rumqopg0	22	8	of	of	IN
cord-312486-rumqopg0	22	9	spike	spike	NN
cord-312486-rumqopg0	22	10	(	(	-LRB-
cord-312486-rumqopg0	22	11	S	s	NN
cord-312486-rumqopg0	22	12	)	)	-RRB-
cord-312486-rumqopg0	22	13	protein	protein	NN
cord-312486-rumqopg0	22	14	causes	cause	VBZ
cord-312486-rumqopg0	22	15	an	an	DT
cord-312486-rumqopg0	22	16	amino	amino	NN
cord-312486-rumqopg0	22	17	acid	acid	NN
cord-312486-rumqopg0	22	18	change	change	NN
cord-312486-rumqopg0	22	19	from	from	IN
cord-312486-rumqopg0	22	20	aspartate	aspartate	NN
cord-312486-rumqopg0	22	21	to	to	IN
cord-312486-rumqopg0	22	22	glycine	glycine	NN
cord-312486-rumqopg0	22	23	.	.	.
cord-312486-rumqopg0	23	1	The	the	DT
cord-312486-rumqopg0	23	2	mutation	mutation	NN
cord-312486-rumqopg0	23	3	that	that	WDT
cord-312486-rumqopg0	23	4	causes	cause	VBZ
cord-312486-rumqopg0	23	5	the	the	DT
cord-312486-rumqopg0	23	6	D614	d614	CD
cord-312486-rumqopg0	23	7	G	g	NN
cord-312486-rumqopg0	23	8	amino	amino	NN
cord-312486-rumqopg0	23	9	change	change	NN
cord-312486-rumqopg0	23	10	is	be	VBZ
cord-312486-rumqopg0	23	11	transmitted	transmit	VBN
cord-312486-rumqopg0	23	12	as	as	IN
cord-312486-rumqopg0	23	13	part	part	NN
cord-312486-rumqopg0	23	14	of	of	IN
cord-312486-rumqopg0	23	15	a	a	DT
cord-312486-rumqopg0	23	16	conserved	conserve	VBN
cord-312486-rumqopg0	23	17	haplotype	haplotype	NN
cord-312486-rumqopg0	23	18	defined	define	VBN
cord-312486-rumqopg0	23	19	by	by	IN
cord-312486-rumqopg0	23	20	four	four	CD
cord-312486-rumqopg0	23	21	SNPs	snp	NNS
cord-312486-rumqopg0	23	22	that	that	WDT
cord-312486-rumqopg0	23	23	almost	almost	RB
cord-312486-rumqopg0	23	24	always	always	RB
cord-312486-rumqopg0	23	25	track	track	VBP
cord-312486-rumqopg0	23	26	together	together	RB
cord-312486-rumqopg0	23	27	,	,	,
cord-312486-rumqopg0	23	28	although	although	IN
cord-312486-rumqopg0	23	29	they	-PRON-	PRP
cord-312486-rumqopg0	23	30	probably	probably	RB
cord-312486-rumqopg0	23	31	arise	arise	VBP
cord-312486-rumqopg0	23	32	independently	independently	RB
cord-312486-rumqopg0	23	33	.	.	.
cord-312486-rumqopg0	24	1	Beside	beside	IN
cord-312486-rumqopg0	24	2	the	the	DT
cord-312486-rumqopg0	24	3	D614	d614	NN
cord-312486-rumqopg0	24	4	G	g	NN
cord-312486-rumqopg0	24	5	mutation	mutation	NN
cord-312486-rumqopg0	24	6	the	the	DT
cord-312486-rumqopg0	24	7	haplotype	haplotype	NN
cord-312486-rumqopg0	24	8	includes	include	VBZ
cord-312486-rumqopg0	24	9	another	another	DT
cord-312486-rumqopg0	24	10	nonsynonymous	nonsynonymous	JJ
cord-312486-rumqopg0	24	11	mutation	mutation	NN
cord-312486-rumqopg0	24	12	(	(	-LRB-
cord-312486-rumqopg0	24	13	P322L	P322L	NNP
cord-312486-rumqopg0	24	14	)	)	-RRB-
cord-312486-rumqopg0	24	15	in	in	IN
cord-312486-rumqopg0	24	16	the	the	DT
cord-312486-rumqopg0	24	17	Nsp12	Nsp12	NNP
cord-312486-rumqopg0	24	18	viral	viral	JJ
cord-312486-rumqopg0	24	19	protein	protein	NN
cord-312486-rumqopg0	24	20	.	.	.
cord-312486-rumqopg0	25	1	While	while	IN
cord-312486-rumqopg0	25	2	the	the	DT
cord-312486-rumqopg0	25	3	functional	functional	JJ
cord-312486-rumqopg0	25	4	consequences	consequence	NNS
cord-312486-rumqopg0	25	5	of	of	IN
cord-312486-rumqopg0	25	6	the	the	DT
cord-312486-rumqopg0	25	7	P322L	P322L	NNP
cord-312486-rumqopg0	25	8	mutation	mutation	NN
cord-312486-rumqopg0	25	9	remain	remain	VBP
cord-312486-rumqopg0	25	10	unclear	unclear	JJ
cord-312486-rumqopg0	25	11	at	at	IN
cord-312486-rumqopg0	25	12	present	present	JJ
cord-312486-rumqopg0	25	13	,	,	,
cord-312486-rumqopg0	25	14	there	there	EX
cord-312486-rumqopg0	25	15	is	be	VBZ
cord-312486-rumqopg0	25	16	strong	strong	JJ
cord-312486-rumqopg0	25	17	evidence	evidence	NN
cord-312486-rumqopg0	25	18	that	that	IN
cord-312486-rumqopg0	25	19	the	the	DT
cord-312486-rumqopg0	25	20	G614	G614	NNP
cord-312486-rumqopg0	25	21	variant	variant	NN
cord-312486-rumqopg0	25	22	is	be	VBZ
cord-312486-rumqopg0	25	23	associated	associate	VBN
cord-312486-rumqopg0	25	24	with	with	IN
cord-312486-rumqopg0	25	25	greater	great	JJR
cord-312486-rumqopg0	25	26	infectivity	infectivity	NN
cord-312486-rumqopg0	25	27	and	and	CC
cord-312486-rumqopg0	25	28	higher	high	JJR
cord-312486-rumqopg0	25	29	viral	viral	JJ
cord-312486-rumqopg0	25	30	loads	load	NNS
cord-312486-rumqopg0	25	31	in	in	IN
cord-312486-rumqopg0	25	32	the	the	DT
cord-312486-rumqopg0	25	33	upper	upper	JJ
cord-312486-rumqopg0	25	34	airways	airway	NNS
cord-312486-rumqopg0	25	35	during	during	IN
cord-312486-rumqopg0	25	36	infection	infection	NN
cord-312486-rumqopg0	25	37	[	[	-LRB-
cord-312486-rumqopg0	25	38	29	29	CD
cord-312486-rumqopg0	25	39	,	,	,
cord-312486-rumqopg0	25	40	[	[	-LRB-
cord-312486-rumqopg0	25	41	32	32	CD
cord-312486-rumqopg0	25	42	]	]	-RRB-
cord-312486-rumqopg0	25	43	[	[	-LRB-
cord-312486-rumqopg0	25	44	33	33	CD
cord-312486-rumqopg0	25	45	]	]	-RRB-
cord-312486-rumqopg0	25	46	[	[	-LRB-
cord-312486-rumqopg0	25	47	34	34	CD
cord-312486-rumqopg0	25	48	]	]	-RRB-
cord-312486-rumqopg0	25	49	[	[	-LRB-
cord-312486-rumqopg0	25	50	35	35	CD
cord-312486-rumqopg0	25	51	]	]	-RRB-
cord-312486-rumqopg0	25	52	.	.	.
cord-312486-rumqopg0	26	1	The	the	DT
cord-312486-rumqopg0	26	2	S	S	NNP
cord-312486-rumqopg0	26	3	protein	protein	NN
cord-312486-rumqopg0	26	4	must	must	MD
cord-312486-rumqopg0	26	5	be	be	VB
cord-312486-rumqopg0	26	6	cleaved	cleave	VBN
cord-312486-rumqopg0	26	7	by	by	IN
cord-312486-rumqopg0	26	8	host	host	NN
cord-312486-rumqopg0	26	9	proteases	protease	NNS
cord-312486-rumqopg0	26	10	to	to	TO
cord-312486-rumqopg0	26	11	enable	enable	VB
cord-312486-rumqopg0	26	12	membrane	membrane	NN
cord-312486-rumqopg0	26	13	fusion	fusion	NN
cord-312486-rumqopg0	26	14	,	,	,
cord-312486-rumqopg0	26	15	which	which	WDT
cord-312486-rumqopg0	26	16	is	be	VBZ
cord-312486-rumqopg0	26	17	critical	critical	JJ
cord-312486-rumqopg0	26	18	for	for	IN
cord-312486-rumqopg0	26	19	viral	viral	JJ
cord-312486-rumqopg0	26	20	entry	entry	NN
cord-312486-rumqopg0	26	21	.	.	.
cord-312486-rumqopg0	27	1	The	the	DT
cord-312486-rumqopg0	27	2	G614	g614	FW
cord-312486-rumqopg0	27	3	mutation	mutation	NN
cord-312486-rumqopg0	27	4	creates	create	VBZ
cord-312486-rumqopg0	27	5	a	a	DT
cord-312486-rumqopg0	27	6	novel	novel	JJ
cord-312486-rumqopg0	27	7	serine	serine	NN
cord-312486-rumqopg0	27	8	protease	protease	NN
cord-312486-rumqopg0	27	9	cleavage	cleavage	NN
cord-312486-rumqopg0	27	10	site	site	NN
cord-312486-rumqopg0	27	11	that	that	WDT
cord-312486-rumqopg0	27	12	can	can	MD
cord-312486-rumqopg0	27	13	facilitate	facilitate	VB
cord-312486-rumqopg0	27	14	its	-PRON-	PRP$
cord-312486-rumqopg0	27	15	cleavage	cleavage	NN
cord-312486-rumqopg0	27	16	by	by	IN
cord-312486-rumqopg0	27	17	host	host	NN
cord-312486-rumqopg0	27	18	serine	serine	NN
cord-312486-rumqopg0	27	19	protease	protease	NN
cord-312486-rumqopg0	27	20	elastase-2	elastase-2	NNP
cord-312486-rumqopg0	27	21	[	[	-LRB-
cord-312486-rumqopg0	27	22	32	32	CD
cord-312486-rumqopg0	27	23	]	]	-RRB-
cord-312486-rumqopg0	27	24	.	.	.
cord-312486-rumqopg0	28	1	Also	also	RB
cord-312486-rumqopg0	28	2	G614	g614	VB
cord-312486-rumqopg0	28	3	mutation	mutation	NN
cord-312486-rumqopg0	28	4	increases	increase	VBZ
cord-312486-rumqopg0	28	5	both	both	DT
cord-312486-rumqopg0	28	6	spike	spike	NN
cord-312486-rumqopg0	28	7	stability	stability	NN
cord-312486-rumqopg0	28	8	and	and	CC
cord-312486-rumqopg0	28	9	membrane	membrane	NN
cord-312486-rumqopg0	28	10	incorporation	incorporation	NN
cord-312486-rumqopg0	28	11	[	[	-LRB-
cord-312486-rumqopg0	28	12	33	33	CD
cord-312486-rumqopg0	28	13	]	]	-RRB-
cord-312486-rumqopg0	28	14	.	.	.
cord-312486-rumqopg0	29	1	In	in	IN
cord-312486-rumqopg0	29	2	cell	cell	NN
cord-312486-rumqopg0	29	3	culture	culture	NN
cord-312486-rumqopg0	29	4	,	,	,
cord-312486-rumqopg0	29	5	S	S	NNP
cord-312486-rumqopg0	29	6	-	-	HYPH
cord-312486-rumqopg0	29	7	G614	G614	NNP
cord-312486-rumqopg0	29	8	pseudovirus	pseudovirus	NNP
cord-312486-rumqopg0	29	9	infected	infect	VBN
cord-312486-rumqopg0	29	10	ACE2-expressing	ace2-expresse	VBG
cord-312486-rumqopg0	29	11	cells	cell	NNS
cord-312486-rumqopg0	29	12	significantly	significantly	RB
cord-312486-rumqopg0	29	13	more	more	RBR
cord-312486-rumqopg0	29	14	efficiently	efficiently	RB
cord-312486-rumqopg0	29	15	than	than	IN
cord-312486-rumqopg0	29	16	the	the	DT
cord-312486-rumqopg0	29	17	S	S	NNP
cord-312486-rumqopg0	29	18	-	-	HYPH
cord-312486-rumqopg0	29	19	D614	D614	NNP
cord-312486-rumqopg0	29	20	pseudovirus	pseudovirus	NNP
cord-312486-rumqopg0	29	21	[	[	-LRB-
cord-312486-rumqopg0	29	22	29	29	CD
cord-312486-rumqopg0	29	23	,	,	,
cord-312486-rumqopg0	29	24	34	34	CD
cord-312486-rumqopg0	29	25	]	]	-RRB-
cord-312486-rumqopg0	29	26	.	.	.
cord-312486-rumqopg0	30	1	Even	even	RB
cord-312486-rumqopg0	30	2	though	though	IN
cord-312486-rumqopg0	30	3	the	the	DT
cord-312486-rumqopg0	30	4	G614	g614	NN
cord-312486-rumqopg0	30	5	variant	variant	NN
cord-312486-rumqopg0	30	6	appears	appear	VBZ
cord-312486-rumqopg0	30	7	to	to	TO
cord-312486-rumqopg0	30	8	be	be	VB
cord-312486-rumqopg0	30	9	more	more	RBR
cord-312486-rumqopg0	30	10	infectious	infectious	JJ
cord-312486-rumqopg0	30	11	,	,	,
cord-312486-rumqopg0	30	12	it	-PRON-	PRP
cord-312486-rumqopg0	30	13	did	do	VBD
cord-312486-rumqopg0	30	14	not	not	RB
cord-312486-rumqopg0	30	15	appear	appear	VB
cord-312486-rumqopg0	30	16	to	to	TO
cord-312486-rumqopg0	30	17	be	be	VB
cord-312486-rumqopg0	30	18	more	more	RBR
cord-312486-rumqopg0	30	19	virulent	virulent	JJ
cord-312486-rumqopg0	30	20	since	since	IN
cord-312486-rumqopg0	30	21	hospital	hospital	NN
cord-312486-rumqopg0	30	22	outcomes	outcome	NNS
cord-312486-rumqopg0	30	23	were	be	VBD
cord-312486-rumqopg0	30	24	similar	similar	JJ
cord-312486-rumqopg0	30	25	with	with	IN
cord-312486-rumqopg0	30	26	either	either	DT
cord-312486-rumqopg0	30	27	variant	variant	NN
cord-312486-rumqopg0	30	28	[	[	-LRB-
cord-312486-rumqopg0	30	29	29	29	CD
cord-312486-rumqopg0	30	30	,	,	,
cord-312486-rumqopg0	30	31	33	33	CD
cord-312486-rumqopg0	30	32	]	]	-RRB-
cord-312486-rumqopg0	30	33	.	.	.
cord-312486-rumqopg0	31	1	Dynamic	dynamic	JJ
cord-312486-rumqopg0	31	2	tracking	tracking	NN
cord-312486-rumqopg0	31	3	of	of	IN
cord-312486-rumqopg0	31	4	variant	variant	JJ
cord-312486-rumqopg0	31	5	frequencies	frequency	NNS
cord-312486-rumqopg0	31	6	sampled	sample	VBN
cord-312486-rumqopg0	31	7	from	from	IN
cord-312486-rumqopg0	31	8	COVID-19	covid-19	JJ
cord-312486-rumqopg0	31	9	patients	patient	NNS
cord-312486-rumqopg0	31	10	from	from	IN
cord-312486-rumqopg0	31	11	Asia	Asia	NNP
cord-312486-rumqopg0	31	12	,	,	,
cord-312486-rumqopg0	31	13	Europe	Europe	NNP
cord-312486-rumqopg0	31	14	,	,	,
cord-312486-rumqopg0	31	15	North	North	NNP
cord-312486-rumqopg0	31	16	America	America	NNP
cord-312486-rumqopg0	31	17	,	,	,
cord-312486-rumqopg0	31	18	and	and	CC
cord-312486-rumqopg0	31	19	Australia	Australia	NNP
cord-312486-rumqopg0	31	20	show	show	VBP
cord-312486-rumqopg0	31	21	that	that	IN
cord-312486-rumqopg0	31	22	the	the	DT
cord-312486-rumqopg0	31	23	D614	d614	CD
cord-312486-rumqopg0	31	24	variant	variant	NN
cord-312486-rumqopg0	31	25	was	be	VBD
cord-312486-rumqopg0	31	26	initially	initially	RB
cord-312486-rumqopg0	31	27	dominant	dominant	JJ
cord-312486-rumqopg0	31	28	,	,	,
cord-312486-rumqopg0	31	29	so	so	CC
cord-312486-rumqopg0	31	30	most	most	JJS
cord-312486-rumqopg0	31	31	subjects	subject	NNS
cord-312486-rumqopg0	31	32	infected	infect	VBN
cord-312486-rumqopg0	31	33	during	during	IN
cord-312486-rumqopg0	31	34	December	December	NNP
cord-312486-rumqopg0	31	35	2019	2019	CD
cord-312486-rumqopg0	31	36	through	through	IN
cord-312486-rumqopg0	31	37	the	the	DT
cord-312486-rumqopg0	31	38	end	end	NN
cord-312486-rumqopg0	31	39	of	of	IN
cord-312486-rumqopg0	31	40	February	February	NNP
cord-312486-rumqopg0	31	41	2020	2020	CD
cord-312486-rumqopg0	31	42	,	,	,
cord-312486-rumqopg0	31	43	had	have	VBD
cord-312486-rumqopg0	31	44	this	this	DT
cord-312486-rumqopg0	31	45	variant	variant	NN
cord-312486-rumqopg0	31	46	[	[	-LRB-
cord-312486-rumqopg0	31	47	29	29	CD
cord-312486-rumqopg0	31	48	]	]	-RRB-
cord-312486-rumqopg0	31	49	.	.	.
cord-312486-rumqopg0	32	1	The	the	DT
cord-312486-rumqopg0	32	2	earliest	early	JJS
cord-312486-rumqopg0	32	3	viral	viral	JJ
cord-312486-rumqopg0	32	4	sequence	sequence	NN
cord-312486-rumqopg0	32	5	that	that	WDT
cord-312486-rumqopg0	32	6	carried	carry	VBD
cord-312486-rumqopg0	32	7	the	the	DT
cord-312486-rumqopg0	32	8	G614	g614	NN
cord-312486-rumqopg0	32	9	mutation	mutation	NN
cord-312486-rumqopg0	32	10	with	with	IN
cord-312486-rumqopg0	32	11	the	the	DT
cord-312486-rumqopg0	32	12	other	other	JJ
cord-312486-rumqopg0	32	13	three	three	CD
cord-312486-rumqopg0	32	14	SNPs	snp	NNS
cord-312486-rumqopg0	32	15	that	that	WDT
cord-312486-rumqopg0	32	16	characterize	characterize	VBP
cord-312486-rumqopg0	32	17	the	the	DT
cord-312486-rumqopg0	32	18	haplotype	haplotype	NN
cord-312486-rumqopg0	32	19	was	be	VBD
cord-312486-rumqopg0	32	20	sampled	sample	VBN
cord-312486-rumqopg0	32	21	in	in	IN
cord-312486-rumqopg0	32	22	Northern	Northern	NNP
cord-312486-rumqopg0	32	23	Italy	Italy	NNP
cord-312486-rumqopg0	32	24	on	on	IN
cord-312486-rumqopg0	32	25	February	February	NNP
cord-312486-rumqopg0	32	26	20	20	CD
cord-312486-rumqopg0	32	27	th	th	XX
cord-312486-rumqopg0	32	28	.	.	.
cord-312486-rumqopg0	33	1	During	during	IN
cord-312486-rumqopg0	33	2	March	March	NNP
cord-312486-rumqopg0	33	3	2020	2020	CD
cord-312486-rumqopg0	33	4	both	both	DT
cord-312486-rumqopg0	33	5	variants	variant	NNS
cord-312486-rumqopg0	33	6	could	could	MD
cord-312486-rumqopg0	33	7	be	be	VB
cord-312486-rumqopg0	33	8	identified	identify	VBN
cord-312486-rumqopg0	33	9	circulating	circulate	VBG
cord-312486-rumqopg0	33	10	in	in	IN
cord-312486-rumqopg0	33	11	the	the	DT
cord-312486-rumqopg0	33	12	population	population	NN
cord-312486-rumqopg0	33	13	[	[	-LRB-
cord-312486-rumqopg0	33	14	29	29	CD
cord-312486-rumqopg0	33	15	,	,	,
cord-312486-rumqopg0	33	16	34	34	CD
cord-312486-rumqopg0	33	17	]	]	-RRB-
cord-312486-rumqopg0	33	18	.	.	.
cord-312486-rumqopg0	34	1	By	by	IN
cord-312486-rumqopg0	34	2	April	April	NNP
cord-312486-rumqopg0	34	3	,	,	,
cord-312486-rumqopg0	34	4	the	the	DT
cord-312486-rumqopg0	34	5	G614	g614	NN
cord-312486-rumqopg0	34	6	variant	variant	NN
cord-312486-rumqopg0	34	7	was	be	VBD
cord-312486-rumqopg0	34	8	circulating	circulate	VBG
cord-312486-rumqopg0	34	9	almost	almost	RB
cord-312486-rumqopg0	34	10	exclusively	exclusively	RB
cord-312486-rumqopg0	34	11	in	in	IN
cord-312486-rumqopg0	34	12	European	European	NNP
cord-312486-rumqopg0	34	13	and	and	CC
cord-312486-rumqopg0	34	14	in	in	IN
cord-312486-rumqopg0	34	15	the	the	DT
cord-312486-rumqopg0	34	16	greater	great	JJR
cord-312486-rumqopg0	34	17	NYC	NYC	NNP
cord-312486-rumqopg0	34	18	area	area	NN
cord-312486-rumqopg0	34	19	.	.	.
cord-312486-rumqopg0	35	1	This	this	DT
cord-312486-rumqopg0	35	2	variant	variant	NN
cord-312486-rumqopg0	35	3	continued	continue	VBD
cord-312486-rumqopg0	35	4	increasing	increase	VBG
cord-312486-rumqopg0	35	5	in	in	IN
cord-312486-rumqopg0	35	6	frequency	frequency	NN
cord-312486-rumqopg0	35	7	over	over	IN
cord-312486-rumqopg0	35	8	several	several	JJ
cord-312486-rumqopg0	35	9	months	month	NNS
cord-312486-rumqopg0	35	10	so	so	IN
cord-312486-rumqopg0	35	11	that	that	IN
cord-312486-rumqopg0	35	12	by	by	IN
cord-312486-rumqopg0	35	13	June	June	NNP
cord-312486-rumqopg0	35	14	2020	2020	CD
cord-312486-rumqopg0	35	15	it	-PRON-	PRP
cord-312486-rumqopg0	35	16	has	have	VBZ
cord-312486-rumqopg0	35	17	become	become	VBN
cord-312486-rumqopg0	35	18	the	the	DT
cord-312486-rumqopg0	35	19	dominant	dominant	JJ
cord-312486-rumqopg0	35	20	variant	variant	NN
cord-312486-rumqopg0	35	21	all	all	RB
cord-312486-rumqopg0	35	22	over	over	IN
cord-312486-rumqopg0	35	23	the	the	DT
cord-312486-rumqopg0	35	24	globe	globe	NN
cord-312486-rumqopg0	35	25	.	.	.
cord-312486-rumqopg0	36	1	It	-PRON-	PRP
cord-312486-rumqopg0	36	2	is	be	VBZ
cord-312486-rumqopg0	36	3	tempting	tempt	VBG
cord-312486-rumqopg0	36	4	to	to	TO
cord-312486-rumqopg0	36	5	hypothesize	hypothesize	VB
cord-312486-rumqopg0	36	6	that	that	IN
cord-312486-rumqopg0	36	7	the	the	DT
cord-312486-rumqopg0	36	8	successful	successful	JJ
cord-312486-rumqopg0	36	9	mitigation	mitigation	NN
cord-312486-rumqopg0	36	10	of	of	IN
cord-312486-rumqopg0	36	11	the	the	DT
cord-312486-rumqopg0	36	12	outbreak	outbreak	NN
cord-312486-rumqopg0	36	13	in	in	IN
cord-312486-rumqopg0	36	14	China	China	NNP
cord-312486-rumqopg0	36	15	and	and	CC
cord-312486-rumqopg0	36	16	several	several	JJ
cord-312486-rumqopg0	36	17	other	other	JJ
cord-312486-rumqopg0	36	18	East	east	JJ
cord-312486-rumqopg0	36	19	Asian	asian	JJ
cord-312486-rumqopg0	36	20	countries	country	NNS
cord-312486-rumqopg0	36	21	was	be	VBD
cord-312486-rumqopg0	36	22	due	due	JJ
cord-312486-rumqopg0	36	23	,	,	,
cord-312486-rumqopg0	36	24	at	at	IN
cord-312486-rumqopg0	36	25	least	least	JJS
cord-312486-rumqopg0	36	26	in	in	IN
cord-312486-rumqopg0	36	27	part	part	NN
cord-312486-rumqopg0	36	28	,	,	,
cord-312486-rumqopg0	36	29	to	to	IN
cord-312486-rumqopg0	36	30	the	the	DT
cord-312486-rumqopg0	36	31	fact	fact	NN
cord-312486-rumqopg0	36	32	that	that	IN
cord-312486-rumqopg0	36	33	they	-PRON-	PRP
cord-312486-rumqopg0	36	34	faced	face	VBD
cord-312486-rumqopg0	36	35	the	the	DT
cord-312486-rumqopg0	36	36	less	less	RBR
cord-312486-rumqopg0	36	37	infective	infective	JJ
cord-312486-rumqopg0	36	38	D614	d614	NN
cord-312486-rumqopg0	36	39	variant	variant	NN
cord-312486-rumqopg0	36	40	.	.	.
cord-312486-rumqopg0	37	1	The	the	DT
cord-312486-rumqopg0	37	2	European	european	JJ
cord-312486-rumqopg0	37	3	countries	country	NNS
cord-312486-rumqopg0	37	4	and	and	CC
cord-312486-rumqopg0	37	5	NYC	NYC	NNP
cord-312486-rumqopg0	37	6	had	have	VBD
cord-312486-rumqopg0	37	7	to	to	TO
cord-312486-rumqopg0	37	8	deal	deal	VB
cord-312486-rumqopg0	37	9	with	with	IN
cord-312486-rumqopg0	37	10	the	the	DT
cord-312486-rumqopg0	37	11	more	more	RBR
cord-312486-rumqopg0	37	12	infectious	infectious	JJ
cord-312486-rumqopg0	37	13	G614	g614	NN
cord-312486-rumqopg0	37	14	variant	variant	NN
cord-312486-rumqopg0	37	15	.	.	.
cord-312486-rumqopg0	38	1	Similarly	similarly	RB
cord-312486-rumqopg0	38	2	,	,	,
cord-312486-rumqopg0	38	3	the	the	DT
cord-312486-rumqopg0	38	4	early	early	JJ
cord-312486-rumqopg0	38	5	outbreak	outbreak	NN
cord-312486-rumqopg0	38	6	in	in	IN
cord-312486-rumqopg0	38	7	Washington	Washington	NNP
cord-312486-rumqopg0	38	8	State	State	NNP
cord-312486-rumqopg0	38	9	was	be	VBD
cord-312486-rumqopg0	38	10	caused	cause	VBN
cord-312486-rumqopg0	38	11	by	by	IN
cord-312486-rumqopg0	38	12	the	the	DT
cord-312486-rumqopg0	38	13	D614	d614	CD
cord-312486-rumqopg0	38	14	variant	variant	NN
cord-312486-rumqopg0	38	15	[	[	-LRB-
cord-312486-rumqopg0	38	16	34	34	CD
cord-312486-rumqopg0	38	17	]	]	-RRB-
cord-312486-rumqopg0	38	18	.	.	.
cord-312486-rumqopg0	39	1	The	the	DT
cord-312486-rumqopg0	39	2	original	original	JJ
cord-312486-rumqopg0	39	3	March	March	NNP
cord-312486-rumqopg0	39	4	-	-	HYPH
cord-312486-rumqopg0	39	5	April	April	NNP
cord-312486-rumqopg0	39	6	outbreak	outbreak	NN
cord-312486-rumqopg0	39	7	on	on	IN
cord-312486-rumqopg0	39	8	the	the	DT
cord-312486-rumqopg0	39	9	Western	Western	NNP
cord-312486-rumqopg0	39	10	Coast	Coast	NNP
cord-312486-rumqopg0	39	11	of	of	IN
cord-312486-rumqopg0	39	12	the	the	DT
cord-312486-rumqopg0	39	13	United	United	NNP
cord-312486-rumqopg0	39	14	States	States	NNP
cord-312486-rumqopg0	39	15	might	may	MD
cord-312486-rumqopg0	39	16	have	have	VB
cord-312486-rumqopg0	39	17	been	be	VBN
cord-312486-rumqopg0	39	18	less	less	RBR
cord-312486-rumqopg0	39	19	severe	severe	JJ
cord-312486-rumqopg0	39	20	than	than	IN
cord-312486-rumqopg0	39	21	in	in	IN
cord-312486-rumqopg0	39	22	the	the	DT
cord-312486-rumqopg0	39	23	Northeastern	Northeastern	NNP
cord-312486-rumqopg0	39	24	United	United	NNP
cord-312486-rumqopg0	39	25	States	States	NNP
cord-312486-rumqopg0	39	26	,	,	,
cord-312486-rumqopg0	39	27	because	because	IN
cord-312486-rumqopg0	39	28	it	-PRON-	PRP
cord-312486-rumqopg0	39	29	originated	originate	VBD
cord-312486-rumqopg0	39	30	from	from	IN
cord-312486-rumqopg0	39	31	the	the	DT
cord-312486-rumqopg0	39	32	Washington	Washington	NNP
cord-312486-rumqopg0	39	33	State	State	NNP
cord-312486-rumqopg0	39	34	D614	D614	NNP
cord-312486-rumqopg0	39	35	variant	variant	NN
cord-312486-rumqopg0	39	36	.	.	.
cord-312486-rumqopg0	40	1	By	by	IN
cord-312486-rumqopg0	40	2	June	June	NNP
cord-312486-rumqopg0	40	3	2020	2020	CD
cord-312486-rumqopg0	40	4	,	,	,
cord-312486-rumqopg0	40	5	the	the	DT
cord-312486-rumqopg0	40	6	G614	g614	NN
cord-312486-rumqopg0	40	7	became	become	VBD
cord-312486-rumqopg0	40	8	the	the	DT
cord-312486-rumqopg0	40	9	global	global	JJ
cord-312486-rumqopg0	40	10	dominant	dominant	JJ
cord-312486-rumqopg0	40	11	variant	variant	NN
cord-312486-rumqopg0	40	12	,	,	,
cord-312486-rumqopg0	40	13	and	and	CC
cord-312486-rumqopg0	40	14	is	be	VBZ
cord-312486-rumqopg0	40	15	responsible	responsible	JJ
cord-312486-rumqopg0	40	16	for	for	IN
cord-312486-rumqopg0	40	17	the	the	DT
cord-312486-rumqopg0	40	18	much	much	RB
cord-312486-rumqopg0	40	19	more	more	RBR
cord-312486-rumqopg0	40	20	infective	infective	JJ
cord-312486-rumqopg0	40	21	July	July	NNP
cord-312486-rumqopg0	40	22	phase	phase	NN
cord-312486-rumqopg0	40	23	of	of	IN
cord-312486-rumqopg0	40	24	the	the	DT
cord-312486-rumqopg0	40	25	outbreak	outbreak	NN
cord-312486-rumqopg0	40	26	in	in	IN
cord-312486-rumqopg0	40	27	the	the	DT
cord-312486-rumqopg0	40	28	Southern	southern	JJ
cord-312486-rumqopg0	40	29	and	and	CC
cord-312486-rumqopg0	40	30	Western	Western	NNP
cord-312486-rumqopg0	40	31	USA	USA	NNP
cord-312486-rumqopg0	40	32	.	.	.
cord-312486-rumqopg0	41	1	The	the	DT
cord-312486-rumqopg0	41	2	viral	viral	JJ
cord-312486-rumqopg0	41	3	genetic	genetic	JJ
cord-312486-rumqopg0	41	4	data	datum	NNS
cord-312486-rumqopg0	41	5	presented	present	VBN
cord-312486-rumqopg0	41	6	clearly	clearly	RB
cord-312486-rumqopg0	41	7	demonstrate	demonstrate	VBP
cord-312486-rumqopg0	41	8	that	that	IN
cord-312486-rumqopg0	41	9	variants	variant	NNS
cord-312486-rumqopg0	41	10	may	may	MD
cord-312486-rumqopg0	41	11	arise	arise	VB
cord-312486-rumqopg0	41	12	quickly	quickly	RB
cord-312486-rumqopg0	41	13	,	,	,
cord-312486-rumqopg0	41	14	even	even	RB
cord-312486-rumqopg0	41	15	in	in	IN
cord-312486-rumqopg0	41	16	CoV	CoV	NNP
cord-312486-rumqopg0	41	17	,	,	,
cord-312486-rumqopg0	41	18	and	and	CC
cord-312486-rumqopg0	41	19	have	have	VBP
cord-312486-rumqopg0	41	20	profound	profound	JJ
cord-312486-rumqopg0	41	21	effects	effect	NNS
cord-312486-rumqopg0	41	22	on	on	IN
cord-312486-rumqopg0	41	23	the	the	DT
cord-312486-rumqopg0	41	24	spread	spread	NN
cord-312486-rumqopg0	41	25	and	and	CC
cord-312486-rumqopg0	41	26	consequences	consequence	NNS
cord-312486-rumqopg0	41	27	of	of	IN
cord-312486-rumqopg0	41	28	the	the	DT
cord-312486-rumqopg0	41	29	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	41	30	pandemic	pandemic	NN
cord-312486-rumqopg0	41	31	.	.	.
cord-312486-rumqopg0	42	1	Prior	prior	JJ
cord-312486-rumqopg0	42	2	research	research	NN
cord-312486-rumqopg0	42	3	has	have	VBZ
cord-312486-rumqopg0	42	4	uncovered	uncover	VBN
cord-312486-rumqopg0	42	5	gene	gene	NN
cord-312486-rumqopg0	42	6	variants	variant	NNS
cord-312486-rumqopg0	42	7	that	that	WDT
cord-312486-rumqopg0	42	8	can	can	MD
cord-312486-rumqopg0	42	9	alter	alter	VB
cord-312486-rumqopg0	42	10	a	a	DT
cord-312486-rumqopg0	42	11	person	person	NN
cord-312486-rumqopg0	42	12	's	's	POS
cord-312486-rumqopg0	42	13	chances	chance	NNS
cord-312486-rumqopg0	42	14	of	of	IN
cord-312486-rumqopg0	42	15	contracting	contract	VBG
cord-312486-rumqopg0	42	16	a	a	DT
cord-312486-rumqopg0	42	17	viral	viral	JJ
cord-312486-rumqopg0	42	18	infectious	infectious	JJ
cord-312486-rumqopg0	42	19	disease	disease	NN
cord-312486-rumqopg0	42	20	.	.	.
cord-312486-rumqopg0	43	1	The	the	DT
cord-312486-rumqopg0	43	2	most	most	RBS
cord-312486-rumqopg0	43	3	famous	famous	JJ
cord-312486-rumqopg0	43	4	example	example	NN
cord-312486-rumqopg0	43	5	is	be	VBZ
cord-312486-rumqopg0	43	6	a	a	DT
cord-312486-rumqopg0	43	7	mutation	mutation	NN
cord-312486-rumqopg0	43	8	in	in	IN
cord-312486-rumqopg0	43	9	the	the	DT
cord-312486-rumqopg0	43	10	CCR5	CCR5	NNP
cord-312486-rumqopg0	43	11	gene	gene	NN
cord-312486-rumqopg0	43	12	,	,	,
cord-312486-rumqopg0	43	13	which	which	WDT
cord-312486-rumqopg0	43	14	offers	offer	VBZ
cord-312486-rumqopg0	43	15	protection	protection	NN
cord-312486-rumqopg0	43	16	against	against	IN
cord-312486-rumqopg0	43	17	HIV	HIV	NNP
cord-312486-rumqopg0	43	18	.	.	.
cord-312486-rumqopg0	44	1	While	while	IN
cord-312486-rumqopg0	44	2	there	there	EX
cord-312486-rumqopg0	44	3	are	be	VBP
cord-312486-rumqopg0	44	4	32	32	CD
cord-312486-rumqopg0	44	5	coding	code	VBG
cord-312486-rumqopg0	44	6	variants	variant	NNS
cord-312486-rumqopg0	44	7	in	in	IN
cord-312486-rumqopg0	44	8	human	human	JJ
cord-312486-rumqopg0	44	9	ACE2	ACE2	NNP
cord-312486-rumqopg0	44	10	,	,	,
cord-312486-rumqopg0	44	11	with	with	IN
cord-312486-rumqopg0	44	12	some	some	DT
cord-312486-rumqopg0	44	13	of	of	IN
cord-312486-rumqopg0	44	14	them	-PRON-	PRP
cord-312486-rumqopg0	44	15	in	in	IN
cord-312486-rumqopg0	44	16	residues	residue	NNS
cord-312486-rumqopg0	44	17	considered	consider	VBN
cord-312486-rumqopg0	44	18	important	important	JJ
cord-312486-rumqopg0	44	19	for	for	IN
cord-312486-rumqopg0	44	20	the	the	DT
cord-312486-rumqopg0	44	21	binding	binding	NN
cord-312486-rumqopg0	44	22	of	of	IN
cord-312486-rumqopg0	44	23	S	s	NN
cord-312486-rumqopg0	44	24	-	-	HYPH
cord-312486-rumqopg0	44	25	protein	protein	NN
cord-312486-rumqopg0	44	26	in	in	IN
cord-312486-rumqopg0	44	27	CoV	CoV	NNP
cord-312486-rumqopg0	44	28	[	[	-LRB-
cord-312486-rumqopg0	44	29	36	36	CD
cord-312486-rumqopg0	44	30	]	]	-RRB-
cord-312486-rumqopg0	44	31	,	,	,
cord-312486-rumqopg0	44	32	there	there	EX
cord-312486-rumqopg0	44	33	is	be	VBZ
cord-312486-rumqopg0	44	34	no	no	DT
cord-312486-rumqopg0	44	35	evidence	evidence	NN
cord-312486-rumqopg0	44	36	for	for	IN
cord-312486-rumqopg0	44	37	the	the	DT
cord-312486-rumqopg0	44	38	existence	existence	NN
cord-312486-rumqopg0	44	39	of	of	IN
cord-312486-rumqopg0	44	40	CoV	CoV	NNP
cord-312486-rumqopg0	44	41	S	S	NNP
cord-312486-rumqopg0	44	42	-	-	HYPH
cord-312486-rumqopg0	44	43	protein	protein	NN
cord-312486-rumqopg0	44	44	-	-	HYPH
cord-312486-rumqopg0	44	45	resistant	resistant	JJ
cord-312486-rumqopg0	44	46	ACE2	ACE2	NNP
cord-312486-rumqopg0	44	47	mutation	mutation	NN
cord-312486-rumqopg0	44	48	in	in	IN
cord-312486-rumqopg0	44	49	any	any	DT
cord-312486-rumqopg0	44	50	population	population	NN
cord-312486-rumqopg0	44	51	[	[	-LRB-
cord-312486-rumqopg0	44	52	37	37	CD
cord-312486-rumqopg0	44	53	]	]	-RRB-
cord-312486-rumqopg0	44	54	.	.	.
cord-312486-rumqopg0	45	1	Neither	neither	DT
cord-312486-rumqopg0	45	2	is	be	VBZ
cord-312486-rumqopg0	45	3	there	there	EX
cord-312486-rumqopg0	45	4	any	any	DT
cord-312486-rumqopg0	45	5	evidence	evidence	NN
cord-312486-rumqopg0	45	6	for	for	IN
cord-312486-rumqopg0	45	7	ACE2	ACE2	NNP
cord-312486-rumqopg0	45	8	variants	variant	NNS
cord-312486-rumqopg0	45	9	that	that	WDT
cord-312486-rumqopg0	45	10	bind	bind	VBP
cord-312486-rumqopg0	45	11	more	more	JJR
cord-312486-rumqopg0	45	12	,	,	,
cord-312486-rumqopg0	45	13	or	or	CC
cord-312486-rumqopg0	45	14	less	less	JJR
cord-312486-rumqopg0	45	15	,	,	,
cord-312486-rumqopg0	45	16	efficiently	efficiently	RB
cord-312486-rumqopg0	45	17	to	to	IN
cord-312486-rumqopg0	45	18	SARS	SARS	NNP
cord-312486-rumqopg0	45	19	-	-	HYPH
cord-312486-rumqopg0	45	20	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	45	21	S	s	NN
cord-312486-rumqopg0	45	22	-	-	HYPH
cord-312486-rumqopg0	45	23	protein	protein	NN
cord-312486-rumqopg0	45	24	.	.	.
cord-312486-rumqopg0	46	1	Based	base	VBN
cord-312486-rumqopg0	46	2	on	on	IN
cord-312486-rumqopg0	46	3	publicly	publicly	RB
cord-312486-rumqopg0	46	4	available	available	JJ
cord-312486-rumqopg0	46	5	data	datum	NNS
cord-312486-rumqopg0	46	6	from	from	IN
cord-312486-rumqopg0	46	7	East	East	NNP
cord-312486-rumqopg0	46	8	Asia	Asia	NNP
cord-312486-rumqopg0	46	9	,	,	,
cord-312486-rumqopg0	46	10	Europe	Europe	NNP
cord-312486-rumqopg0	46	11	and	and	CC
cord-312486-rumqopg0	46	12	North	North	NNP
cord-312486-rumqopg0	46	13	America	America	NNP
cord-312486-rumqopg0	46	14	,	,	,
cord-312486-rumqopg0	46	15	a	a	DT
cord-312486-rumqopg0	46	16	group	group	NN
cord-312486-rumqopg0	46	17	of	of	IN
cord-312486-rumqopg0	46	18	British	british	JJ
cord-312486-rumqopg0	46	19	epidemiologists	epidemiologist	NNS
cord-312486-rumqopg0	46	20	conclude	conclude	VBP
cord-312486-rumqopg0	46	21	that	that	IN
cord-312486-rumqopg0	46	22	children	child	NNS
cord-312486-rumqopg0	46	23	are	be	VBP
cord-312486-rumqopg0	46	24	half	half	RB
cord-312486-rumqopg0	46	25	as	as	RB
cord-312486-rumqopg0	46	26	likely	likely	JJ
cord-312486-rumqopg0	46	27	to	to	TO
cord-312486-rumqopg0	46	28	be	be	VB
cord-312486-rumqopg0	46	29	infected	infect	VBN
cord-312486-rumqopg0	46	30	by	by	IN
cord-312486-rumqopg0	46	31	SARS	SARS	NNP
cord-312486-rumqopg0	46	32	-	-	HYPH
cord-312486-rumqopg0	46	33	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	46	34	as	as	IN
cord-312486-rumqopg0	46	35	adults	adult	NNS
cord-312486-rumqopg0	46	36	[	[	-LRB-
cord-312486-rumqopg0	46	37	38	38	CD
cord-312486-rumqopg0	46	38	]	]	-RRB-
cord-312486-rumqopg0	46	39	.	.	.
cord-312486-rumqopg0	47	1	The	the	DT
cord-312486-rumqopg0	47	2	reliability	reliability	NN
cord-312486-rumqopg0	47	3	of	of	IN
cord-312486-rumqopg0	47	4	these	these	DT
cord-312486-rumqopg0	47	5	estimates	estimate	NNS
cord-312486-rumqopg0	47	6	are	be	VBP
cord-312486-rumqopg0	47	7	limited	limit	VBN
cord-312486-rumqopg0	47	8	by	by	IN
cord-312486-rumqopg0	47	9	lack	lack	NN
cord-312486-rumqopg0	47	10	of	of	IN
cord-312486-rumqopg0	47	11	direct	direct	JJ
cord-312486-rumqopg0	47	12	assessments	assessment	NNS
cord-312486-rumqopg0	47	13	of	of	IN
cord-312486-rumqopg0	47	14	the	the	DT
cord-312486-rumqopg0	47	15	transmission	transmission	NN
cord-312486-rumqopg0	47	16	of	of	IN
cord-312486-rumqopg0	47	17	the	the	DT
cord-312486-rumqopg0	47	18	virus	virus	NN
cord-312486-rumqopg0	47	19	between	between	IN
cord-312486-rumqopg0	47	20	adult	adult	NN
cord-312486-rumqopg0	47	21	to	to	IN
cord-312486-rumqopg0	47	22	child	child	NN
cord-312486-rumqopg0	47	23	,	,	,
cord-312486-rumqopg0	47	24	and	and	CC
cord-312486-rumqopg0	47	25	child	child	NN
cord-312486-rumqopg0	47	26	to	to	IN
cord-312486-rumqopg0	47	27	child	child	NN
cord-312486-rumqopg0	47	28	,	,	,
cord-312486-rumqopg0	47	29	compared	compare	VBN
cord-312486-rumqopg0	47	30	with	with	IN
cord-312486-rumqopg0	47	31	adult	adult	NN
cord-312486-rumqopg0	47	32	to	to	IN
cord-312486-rumqopg0	47	33	adult	adult	NN
cord-312486-rumqopg0	47	34	.	.	.
cord-312486-rumqopg0	48	1	Furthermore	furthermore	RB
cord-312486-rumqopg0	48	2	,	,	,
cord-312486-rumqopg0	48	3	because	because	IN
cord-312486-rumqopg0	48	4	children	child	NNS
cord-312486-rumqopg0	48	5	tend	tend	VBP
cord-312486-rumqopg0	48	6	to	to	TO
cord-312486-rumqopg0	48	7	have	have	VB
cord-312486-rumqopg0	48	8	less	less	JJR
cord-312486-rumqopg0	48	9	comorbidities	comorbiditie	NNS
cord-312486-rumqopg0	48	10	than	than	IN
cord-312486-rumqopg0	48	11	adults	adult	NNS
cord-312486-rumqopg0	48	12	,	,	,
cord-312486-rumqopg0	48	13	they	-PRON-	PRP
cord-312486-rumqopg0	48	14	experience	experience	VBP
cord-312486-rumqopg0	48	15	less	less	JJR
cord-312486-rumqopg0	48	16	disease	disease	NN
cord-312486-rumqopg0	48	17	symptoms	symptom	NNS
cord-312486-rumqopg0	48	18	,	,	,
cord-312486-rumqopg0	48	19	and	and	CC
cord-312486-rumqopg0	48	20	as	as	IN
cord-312486-rumqopg0	48	21	such	such	JJ
cord-312486-rumqopg0	48	22	are	be	VBP
cord-312486-rumqopg0	48	23	tested	test	VBN
cord-312486-rumqopg0	48	24	less	less	JJR
cord-312486-rumqopg0	48	25	than	than	IN
cord-312486-rumqopg0	48	26	adults	adult	NNS
cord-312486-rumqopg0	48	27	.	.	.
cord-312486-rumqopg0	49	1	Hence	hence	RB
cord-312486-rumqopg0	49	2	,	,	,
cord-312486-rumqopg0	49	3	the	the	DT
cord-312486-rumqopg0	49	4	number	number	NN
cord-312486-rumqopg0	49	5	of	of	IN
cord-312486-rumqopg0	49	6	children	child	NNS
cord-312486-rumqopg0	49	7	infected	infect	VBN
cord-312486-rumqopg0	49	8	may	may	MD
cord-312486-rumqopg0	49	9	be	be	VB
cord-312486-rumqopg0	49	10	grossly	grossly	RB
cord-312486-rumqopg0	49	11	undercounted	undercounte	VBN
cord-312486-rumqopg0	49	12	.	.	.
cord-312486-rumqopg0	50	1	A	a	DT
cord-312486-rumqopg0	50	2	publication	publication	NN
cord-312486-rumqopg0	50	3	that	that	IN
cord-312486-rumqopg0	50	4	in	in	IN
cord-312486-rumqopg0	50	5	this	this	DT
cord-312486-rumqopg0	50	6	short	short	JJ
cord-312486-rumqopg0	50	7	timeframe	timeframe	NN
cord-312486-rumqopg0	50	8	has	have	VBZ
cord-312486-rumqopg0	50	9	already	already	RB
cord-312486-rumqopg0	50	10	been	be	VBN
cord-312486-rumqopg0	50	11	cited	cite	VBN
cord-312486-rumqopg0	50	12	frequently	frequently	RB
cord-312486-rumqopg0	50	13	,	,	,
cord-312486-rumqopg0	50	14	seeks	seek	VBZ
cord-312486-rumqopg0	50	15	to	to	TO
cord-312486-rumqopg0	50	16	confirm	confirm	VB
cord-312486-rumqopg0	50	17	that	that	IN
cord-312486-rumqopg0	50	18	the	the	DT
cord-312486-rumqopg0	50	19	incidence	incidence	NN
cord-312486-rumqopg0	50	20	of	of	IN
cord-312486-rumqopg0	50	21	SARS	SARS	NNP
cord-312486-rumqopg0	50	22	-	-	HYPH
cord-312486-rumqopg0	50	23	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	50	24	infection	infection	NN
cord-312486-rumqopg0	50	25	is	be	VBZ
cord-312486-rumqopg0	50	26	lower	low	JJR
cord-312486-rumqopg0	50	27	in	in	IN
cord-312486-rumqopg0	50	28	children	child	NNS
cord-312486-rumqopg0	50	29	than	than	IN
cord-312486-rumqopg0	50	30	adults	adult	NNS
cord-312486-rumqopg0	50	31	due	due	JJ
cord-312486-rumqopg0	50	32	to	to	IN
cord-312486-rumqopg0	50	33	a	a	DT
cord-312486-rumqopg0	50	34	lower	low	JJR
cord-312486-rumqopg0	50	35	density	density	NN
cord-312486-rumqopg0	50	36	of	of	IN
cord-312486-rumqopg0	50	37	ACE2	ACE2	NNP
cord-312486-rumqopg0	50	38	receptors	receptor	NNS
cord-312486-rumqopg0	50	39	in	in	IN
cord-312486-rumqopg0	50	40	the	the	DT
cord-312486-rumqopg0	50	41	nasal	nasal	NN
cord-312486-rumqopg0	50	42	epithelium	epithelium	NN
cord-312486-rumqopg0	50	43	of	of	IN
cord-312486-rumqopg0	50	44	children	child	NNS
cord-312486-rumqopg0	50	45	as	as	IN
cord-312486-rumqopg0	50	46	compared	compare	VBN
cord-312486-rumqopg0	50	47	to	to	IN
cord-312486-rumqopg0	50	48	adults	adult	NNS
cord-312486-rumqopg0	50	49	[	[	-LRB-
cord-312486-rumqopg0	50	50	39	39	CD
cord-312486-rumqopg0	50	51	]	]	-RRB-
cord-312486-rumqopg0	50	52	.	.	.
cord-312486-rumqopg0	51	1	The	the	DT
cord-312486-rumqopg0	51	2	researchers	researcher	NNS
cord-312486-rumqopg0	51	3	report	report	VBP
cord-312486-rumqopg0	51	4	finding	find	VBG
cord-312486-rumqopg0	51	5	less	less	JJR
cord-312486-rumqopg0	51	6	ACE2	ACE2	NNP
cord-312486-rumqopg0	51	7	RNA	RNA	NNP
cord-312486-rumqopg0	51	8	in	in	IN
cord-312486-rumqopg0	51	9	cells	cell	NNS
cord-312486-rumqopg0	51	10	scraped	scrape	VBN
cord-312486-rumqopg0	51	11	from	from	IN
cord-312486-rumqopg0	51	12	the	the	DT
cord-312486-rumqopg0	51	13	noses	nose	NNS
cord-312486-rumqopg0	51	14	of	of	IN
cord-312486-rumqopg0	51	15	children	child	NNS
cord-312486-rumqopg0	51	16	than	than	IN
cord-312486-rumqopg0	51	17	in	in	IN
cord-312486-rumqopg0	51	18	those	those	DT
cord-312486-rumqopg0	51	19	from	from	IN
cord-312486-rumqopg0	51	20	adults	adult	NNS
cord-312486-rumqopg0	51	21	.	.	.
cord-312486-rumqopg0	52	1	The	the	DT
cord-312486-rumqopg0	52	2	significant	significant	JJ
cord-312486-rumqopg0	52	3	difference	difference	NN
cord-312486-rumqopg0	52	4	in	in	IN
cord-312486-rumqopg0	52	5	this	this	DT
cord-312486-rumqopg0	52	6	study	study	NN
cord-312486-rumqopg0	52	7	is	be	VBZ
cord-312486-rumqopg0	52	8	reported	report	VBN
cord-312486-rumqopg0	52	9	to	to	TO
cord-312486-rumqopg0	52	10	be	be	VB
cord-312486-rumqopg0	52	11	between	between	IN
cord-312486-rumqopg0	52	12	those	those	DT
cord-312486-rumqopg0	52	13	under	under	IN
cord-312486-rumqopg0	52	14	17	17	CD
cord-312486-rumqopg0	52	15	,	,	,
cord-312486-rumqopg0	52	16	and	and	CC
cord-312486-rumqopg0	52	17	those	those	DT
cord-312486-rumqopg0	52	18	aged	aged	JJ
cord-312486-rumqopg0	52	19	18	18	CD
cord-312486-rumqopg0	52	20	-	-	SYM
cord-312486-rumqopg0	52	21	60	60	CD
cord-312486-rumqopg0	52	22	.	.	.
cord-312486-rumqopg0	53	1	In	in	IN
cord-312486-rumqopg0	53	2	addition	addition	NN
cord-312486-rumqopg0	53	3	,	,	,
cord-312486-rumqopg0	53	4	there	there	EX
cord-312486-rumqopg0	53	5	was	be	VBD
cord-312486-rumqopg0	53	6	no	no	DT
cord-312486-rumqopg0	53	7	difference	difference	NN
cord-312486-rumqopg0	53	8	in	in	IN
cord-312486-rumqopg0	53	9	the	the	DT
cord-312486-rumqopg0	53	10	amount	amount	NN
cord-312486-rumqopg0	53	11	of	of	IN
cord-312486-rumqopg0	53	12	ACE2	ACE2	NNP
cord-312486-rumqopg0	53	13	RNA	RNA	NNP
cord-312486-rumqopg0	53	14	detected	detect	VBD
cord-312486-rumqopg0	53	15	according	accord	VBG
cord-312486-rumqopg0	53	16	to	to	IN
cord-312486-rumqopg0	53	17	gender	gender	NN
cord-312486-rumqopg0	53	18	,	,	,
cord-312486-rumqopg0	53	19	or	or	CC
cord-312486-rumqopg0	53	20	those	those	DT
cord-312486-rumqopg0	53	21	with	with	IN
cord-312486-rumqopg0	53	22	or	or	CC
cord-312486-rumqopg0	53	23	without	without	IN
cord-312486-rumqopg0	53	24	asthma	asthma	NN
cord-312486-rumqopg0	53	25	.	.	.
cord-312486-rumqopg0	54	1	Several	several	JJ
cord-312486-rumqopg0	54	2	caveats	caveat	NNS
cord-312486-rumqopg0	54	3	to	to	TO
cord-312486-rumqopg0	54	4	consider	consider	VB
cord-312486-rumqopg0	54	5	:	:	:
cord-312486-rumqopg0	54	6	The	the	DT
cord-312486-rumqopg0	54	7	average	average	JJ
cord-312486-rumqopg0	54	8	relative	relative	JJ
cord-312486-rumqopg0	54	9	amount	amount	NN
cord-312486-rumqopg0	54	10	of	of	IN
cord-312486-rumqopg0	54	11	RNA	RNA	NNP
cord-312486-rumqopg0	54	12	ranged	range	VBD
cord-312486-rumqopg0	54	13	from	from	IN
cord-312486-rumqopg0	54	14	2.4	2.4	CD
cord-312486-rumqopg0	54	15	for	for	IN
cord-312486-rumqopg0	54	16	those	those	DT
cord-312486-rumqopg0	54	17	less	less	JJR
cord-312486-rumqopg0	54	18	than	than	IN
cord-312486-rumqopg0	54	19	10	10	CD
cord-312486-rumqopg0	54	20	years	year	NNS
cord-312486-rumqopg0	54	21	old	old	JJ
cord-312486-rumqopg0	54	22	,	,	,
cord-312486-rumqopg0	54	23	to	to	IN
cord-312486-rumqopg0	54	24	3.09	3.09	CD
cord-312486-rumqopg0	54	25	for	for	IN
cord-312486-rumqopg0	54	26	those	those	DT
cord-312486-rumqopg0	54	27	25	25	CD
cord-312486-rumqopg0	54	28	and	and	CC
cord-312486-rumqopg0	54	29	older	old	JJR
cord-312486-rumqopg0	54	30	.	.	.
cord-312486-rumqopg0	55	1	The	the	DT
cord-312486-rumqopg0	55	2	differences	difference	NNS
cord-312486-rumqopg0	55	3	are	be	VBP
cord-312486-rumqopg0	55	4	relatively	relatively	RB
cord-312486-rumqopg0	55	5	small	small	JJ
cord-312486-rumqopg0	55	6	and	and	CC
cord-312486-rumqopg0	55	7	the	the	DT
cord-312486-rumqopg0	55	8	error	error	NN
cord-312486-rumqopg0	55	9	bars	bar	VBZ
cord-312486-rumqopg0	55	10	large	large	JJ
cord-312486-rumqopg0	55	11	.	.	.
cord-312486-rumqopg0	56	1	While	while	IN
cord-312486-rumqopg0	56	2	those	those	DT
cord-312486-rumqopg0	56	3	over	over	IN
cord-312486-rumqopg0	56	4	60	60	CD
cord-312486-rumqopg0	56	5	are	be	VBP
cord-312486-rumqopg0	56	6	those	those	DT
cord-312486-rumqopg0	56	7	most	most	RBS
cord-312486-rumqopg0	56	8	affected	affect	VBN
cord-312486-rumqopg0	56	9	by	by	IN
cord-312486-rumqopg0	56	10	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	56	11	,	,	,
cord-312486-rumqopg0	56	12	the	the	DT
cord-312486-rumqopg0	56	13	study	study	NN
cord-312486-rumqopg0	56	14	did	do	VBD
cord-312486-rumqopg0	56	15	not	not	RB
cord-312486-rumqopg0	56	16	include	include	VB
cord-312486-rumqopg0	56	17	individuals	individual	NNS
cord-312486-rumqopg0	56	18	older	old	JJR
cord-312486-rumqopg0	56	19	than	than	IN
cord-312486-rumqopg0	56	20	60	60	CD
cord-312486-rumqopg0	56	21	years	year	NNS
cord-312486-rumqopg0	56	22	.	.	.
cord-312486-rumqopg0	57	1	Also	also	RB
cord-312486-rumqopg0	57	2	,	,	,
cord-312486-rumqopg0	57	3	the	the	DT
cord-312486-rumqopg0	57	4	density	density	NN
cord-312486-rumqopg0	57	5	of	of	IN
cord-312486-rumqopg0	57	6	ACE2	ACE2	NNP
cord-312486-rumqopg0	57	7	receptors	receptor	NNS
cord-312486-rumqopg0	57	8	may	may	MD
cord-312486-rumqopg0	57	9	not	not	RB
cord-312486-rumqopg0	57	10	be	be	VB
cord-312486-rumqopg0	57	11	uniform	uniform	JJ
cord-312486-rumqopg0	57	12	throughout	throughout	IN
cord-312486-rumqopg0	57	13	the	the	DT
cord-312486-rumqopg0	57	14	nasal	nasal	NN
cord-312486-rumqopg0	57	15	mucosa	mucosa	NN
cord-312486-rumqopg0	57	16	,	,	,
cord-312486-rumqopg0	57	17	and	and	CC
cord-312486-rumqopg0	57	18	no	no	DT
cord-312486-rumqopg0	57	19	evidence	evidence	NN
cord-312486-rumqopg0	57	20	is	be	VBZ
cord-312486-rumqopg0	57	21	presented	present	VBN
cord-312486-rumqopg0	57	22	that	that	IN
cord-312486-rumqopg0	57	23	the	the	DT
cord-312486-rumqopg0	57	24	entire	entire	JJ
cord-312486-rumqopg0	57	25	nasal	nasal	NN
cord-312486-rumqopg0	57	26	mucosa	mucosa	NN
cord-312486-rumqopg0	57	27	was	be	VBD
cord-312486-rumqopg0	58	1	J	J	NNP
cord-312486-rumqopg0	58	2	o	o	NN
cord-312486-rumqopg0	58	3	u	u	NN
cord-312486-rumqopg0	58	4	r	r	NN
cord-312486-rumqopg0	58	5	n	n	NN
cord-312486-rumqopg0	58	6	a	a	DT
cord-312486-rumqopg0	58	7	l	l	NN
cord-312486-rumqopg0	58	8	P	p	NN
cord-312486-rumqopg0	58	9	r	r	NN
cord-312486-rumqopg0	58	10	e	e	NN
cord-312486-rumqopg0	59	1	-p	-p	:
cord-312486-rumqopg0	60	1	r	r	NN
cord-312486-rumqopg0	60	2	o	o	NN
cord-312486-rumqopg0	60	3	o	o	NN
cord-312486-rumqopg0	60	4	f	f	NN
cord-312486-rumqopg0	60	5	equally	equally	RB
cord-312486-rumqopg0	60	6	sampled	sample	VBN
cord-312486-rumqopg0	60	7	.	.	.
cord-312486-rumqopg0	61	1	Lastly	lastly	RB
cord-312486-rumqopg0	61	2	,	,	,
cord-312486-rumqopg0	61	3	it	-PRON-	PRP
cord-312486-rumqopg0	61	4	is	be	VBZ
cord-312486-rumqopg0	61	5	unknown	unknown	JJ
cord-312486-rumqopg0	61	6	how	how	WRB
cord-312486-rumqopg0	61	7	many	many	JJ
cord-312486-rumqopg0	61	8	receptors	receptor	NNS
cord-312486-rumqopg0	61	9	are	be	VBP
cord-312486-rumqopg0	61	10	needed	need	VBN
cord-312486-rumqopg0	61	11	for	for	IN
cord-312486-rumqopg0	61	12	the	the	DT
cord-312486-rumqopg0	61	13	SARS	SARS	NNP
cord-312486-rumqopg0	61	14	-	-	HYPH
cord-312486-rumqopg0	61	15	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	61	16	virus	virus	NN
cord-312486-rumqopg0	61	17	to	to	TO
cord-312486-rumqopg0	61	18	successfully	successfully	RB
cord-312486-rumqopg0	61	19	infect	infect	VB
cord-312486-rumqopg0	61	20	us	-PRON-	PRP
cord-312486-rumqopg0	61	21	.	.	.
cord-312486-rumqopg0	62	1	In	in	IN
cord-312486-rumqopg0	62	2	any	any	DT
cord-312486-rumqopg0	62	3	case	case	NN
cord-312486-rumqopg0	62	4	,	,	,
cord-312486-rumqopg0	62	5	there	there	EX
cord-312486-rumqopg0	62	6	is	be	VBZ
cord-312486-rumqopg0	62	7	no	no	DT
cord-312486-rumqopg0	62	8	doubt	doubt	NN
cord-312486-rumqopg0	62	9	that	that	IN
cord-312486-rumqopg0	62	10	children	child	NNS
cord-312486-rumqopg0	62	11	of	of	IN
cord-312486-rumqopg0	62	12	any	any	DT
cord-312486-rumqopg0	62	13	age	age	NN
cord-312486-rumqopg0	62	14	can	can	MD
cord-312486-rumqopg0	62	15	be	be	VB
cord-312486-rumqopg0	62	16	infected	infect	VBN
cord-312486-rumqopg0	62	17	.	.	.
cord-312486-rumqopg0	63	1	I	-PRON-	PRP
cord-312486-rumqopg0	63	2	am	be	VBP
cord-312486-rumqopg0	63	3	more	more	RBR
cord-312486-rumqopg0	63	4	convinced	convinced	JJ
cord-312486-rumqopg0	63	5	by	by	IN
cord-312486-rumqopg0	63	6	the	the	DT
cord-312486-rumqopg0	63	7	conclusions	conclusion	NNS
cord-312486-rumqopg0	63	8	of	of	IN
cord-312486-rumqopg0	63	9	Dong	Dong	NNP
cord-312486-rumqopg0	63	10	et	et	FW
cord-312486-rumqopg0	63	11	al	al	NNP
cord-312486-rumqopg0	63	12	.	.	.
cord-312486-rumqopg0	64	1	[	[	-LRB-
cord-312486-rumqopg0	64	2	40	40	CD
cord-312486-rumqopg0	64	3	]	]	-RRB-
cord-312486-rumqopg0	64	4	that	that	IN
cord-312486-rumqopg0	64	5	children	child	NNS
cord-312486-rumqopg0	64	6	of	of	IN
cord-312486-rumqopg0	64	7	all	all	DT
cord-312486-rumqopg0	64	8	ages	age	NNS
cord-312486-rumqopg0	64	9	are	be	VBP
cord-312486-rumqopg0	64	10	susceptible	susceptible	JJ
cord-312486-rumqopg0	64	11	to	to	IN
cord-312486-rumqopg0	64	12	infection	infection	NN
cord-312486-rumqopg0	64	13	by	by	IN
cord-312486-rumqopg0	64	14	SARS	SARS	NNP
cord-312486-rumqopg0	64	15	-	-	HYPH
cord-312486-rumqopg0	64	16	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	64	17	without	without	IN
cord-312486-rumqopg0	64	18	significant	significant	JJ
cord-312486-rumqopg0	64	19	sex	sex	NN
cord-312486-rumqopg0	64	20	differences	difference	NNS
cord-312486-rumqopg0	64	21	.	.	.
cord-312486-rumqopg0	65	1	Although	although	IN
cord-312486-rumqopg0	65	2	clinical	clinical	JJ
cord-312486-rumqopg0	65	3	manifestations	manifestation	NNS
cord-312486-rumqopg0	65	4	of	of	IN
cord-312486-rumqopg0	65	5	children	child	NNS
cord-312486-rumqopg0	65	6	's	's	POS
cord-312486-rumqopg0	65	7	COVID-19	covid-19	CD
cord-312486-rumqopg0	65	8	cases	case	NNS
cord-312486-rumqopg0	65	9	seem	seem	VBP
cord-312486-rumqopg0	65	10	generally	generally	RB
cord-312486-rumqopg0	65	11	less	less	RBR
cord-312486-rumqopg0	65	12	severe	severe	JJ
cord-312486-rumqopg0	65	13	than	than	IN
cord-312486-rumqopg0	65	14	those	those	DT
cord-312486-rumqopg0	65	15	of	of	IN
cord-312486-rumqopg0	65	16	adult	adult	NN
cord-312486-rumqopg0	65	17	patients	patient	NNS
cord-312486-rumqopg0	65	18	,	,	,
cord-312486-rumqopg0	65	19	young	young	JJ
cord-312486-rumqopg0	65	20	children	child	NNS
cord-312486-rumqopg0	65	21	,	,	,
cord-312486-rumqopg0	65	22	particularly	particularly	RB
cord-312486-rumqopg0	65	23	infants	infant	NNS
cord-312486-rumqopg0	65	24	,	,	,
cord-312486-rumqopg0	65	25	are	be	VBP
cord-312486-rumqopg0	65	26	vulnerable	vulnerable	JJ
cord-312486-rumqopg0	65	27	to	to	IN
cord-312486-rumqopg0	65	28	infection	infection	NN
cord-312486-rumqopg0	65	29	.	.	.
cord-312486-rumqopg0	66	1	As	as	IN
cord-312486-rumqopg0	66	2	the	the	DT
cord-312486-rumqopg0	66	3	aforementioned	aforementioned	JJ
cord-312486-rumqopg0	66	4	publication	publication	NN
cord-312486-rumqopg0	66	5	[	[	-LRB-
cord-312486-rumqopg0	66	6	39	39	CD
cord-312486-rumqopg0	66	7	]	]	-RRB-
cord-312486-rumqopg0	66	8	assumes	assume	VBZ
cord-312486-rumqopg0	66	9	,	,	,
cord-312486-rumqopg0	66	10	if	if	IN
cord-312486-rumqopg0	66	11	ACE2	ACE2	NNP
cord-312486-rumqopg0	66	12	is	be	VBZ
cord-312486-rumqopg0	66	13	the	the	DT
cord-312486-rumqopg0	66	14	sole	sole	JJ
cord-312486-rumqopg0	66	15	receptor	receptor	NN
cord-312486-rumqopg0	66	16	for	for	IN
cord-312486-rumqopg0	66	17	viral	viral	JJ
cord-312486-rumqopg0	66	18	entry	entry	NN
cord-312486-rumqopg0	66	19	,	,	,
cord-312486-rumqopg0	66	20	then	then	RB
cord-312486-rumqopg0	66	21	the	the	DT
cord-312486-rumqopg0	66	22	expectation	expectation	NN
cord-312486-rumqopg0	66	23	is	be	VBZ
cord-312486-rumqopg0	66	24	that	that	IN
cord-312486-rumqopg0	66	25	high	high	JJ
cord-312486-rumqopg0	66	26	ACE2	ACE2	NNP
cord-312486-rumqopg0	66	27	tissue	tissue	NN
cord-312486-rumqopg0	66	28	expression	expression	NN
cord-312486-rumqopg0	66	29	equals	equal	VBZ
cord-312486-rumqopg0	66	30	higher	high	JJR
cord-312486-rumqopg0	66	31	infectivity	infectivity	NN
cord-312486-rumqopg0	66	32	and	and	CC
cord-312486-rumqopg0	66	33	worse	bad	JJR
cord-312486-rumqopg0	66	34	outcomes	outcome	NNS
cord-312486-rumqopg0	66	35	.	.	.
cord-312486-rumqopg0	67	1	However	however	RB
cord-312486-rumqopg0	67	2	,	,	,
cord-312486-rumqopg0	67	3	a	a	DT
cord-312486-rumqopg0	67	4	careful	careful	JJ
cord-312486-rumqopg0	67	5	consideration	consideration	NN
cord-312486-rumqopg0	67	6	of	of	IN
cord-312486-rumqopg0	67	7	the	the	DT
cord-312486-rumqopg0	67	8	role	role	NN
cord-312486-rumqopg0	67	9	of	of	IN
cord-312486-rumqopg0	67	10	ACE2	ACE2	NNP
cord-312486-rumqopg0	67	11	in	in	IN
cord-312486-rumqopg0	67	12	the	the	DT
cord-312486-rumqopg0	67	13	renin	renin	NN
cord-312486-rumqopg0	67	14	-	-	HYPH
cord-312486-rumqopg0	67	15	angiotensin	angiotensin	NN
cord-312486-rumqopg0	67	16	system	system	NN
cord-312486-rumqopg0	67	17	physiopathology	physiopathology	NN
cord-312486-rumqopg0	67	18	is	be	VBZ
cord-312486-rumqopg0	67	19	indicative	indicative	JJ
cord-312486-rumqopg0	67	20	of	of	IN
cord-312486-rumqopg0	67	21	it	-PRON-	PRP
cord-312486-rumqopg0	67	22	playing	play	VBG
cord-312486-rumqopg0	67	23	a	a	DT
cord-312486-rumqopg0	67	24	protective	protective	JJ
cord-312486-rumqopg0	67	25	role	role	NN
cord-312486-rumqopg0	67	26	-	-	HYPH
cord-312486-rumqopg0	67	27	meaning	meaning	NN
cord-312486-rumqopg0	68	1	higher	high	JJR
cord-312486-rumqopg0	68	2	ACE2	ACE2	NNP
cord-312486-rumqopg0	68	3	expression	expression	NN
cord-312486-rumqopg0	68	4	is	be	VBZ
cord-312486-rumqopg0	68	5	more	more	RBR
cord-312486-rumqopg0	68	6	likely	likely	JJ
cord-312486-rumqopg0	68	7	to	to	TO
cord-312486-rumqopg0	68	8	protect	protect	VB
cord-312486-rumqopg0	68	9	us	-PRON-	PRP
cord-312486-rumqopg0	68	10	from	from	IN
cord-312486-rumqopg0	68	11	a	a	DT
cord-312486-rumqopg0	68	12	worse	bad	JJR
cord-312486-rumqopg0	68	13	outcome	outcome	NN
cord-312486-rumqopg0	68	14	of	of	IN
cord-312486-rumqopg0	68	15	viral	viral	JJ
cord-312486-rumqopg0	68	16	infection	infection	NN
cord-312486-rumqopg0	68	17	.	.	.
cord-312486-rumqopg0	69	1	As	as	IN
cord-312486-rumqopg0	69	2	such	such	JJ
cord-312486-rumqopg0	69	3	,	,	,
cord-312486-rumqopg0	69	4	ACE2	ACE2	NNP
cord-312486-rumqopg0	69	5	has	have	VBZ
cord-312486-rumqopg0	69	6	an	an	DT
cord-312486-rumqopg0	69	7	important	important	JJ
cord-312486-rumqopg0	69	8	role	role	NN
cord-312486-rumqopg0	69	9	in	in	IN
cord-312486-rumqopg0	69	10	counterbalancing	counterbalance	VBG
cord-312486-rumqopg0	69	11	the	the	DT
cord-312486-rumqopg0	69	12	effects	effect	NNS
cord-312486-rumqopg0	69	13	of	of	IN
cord-312486-rumqopg0	69	14	ACE1	ace1	CD
cord-312486-rumqopg0	69	15	.	.	.
cord-312486-rumqopg0	70	1	Angiotensin	Angiotensin	NNP
cord-312486-rumqopg0	70	2	II	II	NNP
cord-312486-rumqopg0	70	3	,	,	,
cord-312486-rumqopg0	70	4	a	a	DT
cord-312486-rumqopg0	70	5	product	product	NN
cord-312486-rumqopg0	70	6	of	of	IN
cord-312486-rumqopg0	70	7	ACE1	ace1	CD
cord-312486-rumqopg0	71	1	cleaving	cleave	VBG
cord-312486-rumqopg0	71	2	angiotensin	angiotensin	NN
cord-312486-rumqopg0	71	3	I	-PRON-	PRP
cord-312486-rumqopg0	71	4	,	,	,
cord-312486-rumqopg0	71	5	can	can	MD
cord-312486-rumqopg0	71	6	cause	cause	VB
cord-312486-rumqopg0	71	7	vasoconstriction	vasoconstriction	NN
cord-312486-rumqopg0	71	8	,	,	,
cord-312486-rumqopg0	71	9	inflammation	inflammation	NN
cord-312486-rumqopg0	71	10	,	,	,
cord-312486-rumqopg0	71	11	and	and	CC
cord-312486-rumqopg0	71	12	fibrosis	fibrosis	NN
cord-312486-rumqopg0	71	13	.	.	.
cord-312486-rumqopg0	72	1	ACE2	ACE2	NNP
cord-312486-rumqopg0	72	2	cleaves	cleave	VBZ
cord-312486-rumqopg0	72	3	angiotensin	angiotensin	NN
cord-312486-rumqopg0	72	4	II	II	NNP
cord-312486-rumqopg0	72	5	to	to	IN
cord-312486-rumqopg0	72	6	angiotensin	angiotensin	NN
cord-312486-rumqopg0	72	7	1	1	CD
cord-312486-rumqopg0	72	8	-	-	SYM
cord-312486-rumqopg0	72	9	7	7	CD
cord-312486-rumqopg0	72	10	,	,	,
cord-312486-rumqopg0	72	11	which	which	WDT
cord-312486-rumqopg0	72	12	antagonizes	antagonize	VBZ
cord-312486-rumqopg0	72	13	the	the	DT
cord-312486-rumqopg0	72	14	activities	activity	NNS
cord-312486-rumqopg0	72	15	of	of	IN
cord-312486-rumqopg0	72	16	angiotensin	angiotensin	NN
cord-312486-rumqopg0	72	17	II-	II-	NNP
cord-312486-rumqopg0	73	1	hence	hence	RB
cord-312486-rumqopg0	73	2	,	,	,
cord-312486-rumqopg0	73	3	it	-PRON-	PRP
cord-312486-rumqopg0	73	4	can	can	MD
cord-312486-rumqopg0	73	5	suppress	suppress	VB
cord-312486-rumqopg0	73	6	inflammation	inflammation	NN
cord-312486-rumqopg0	73	7	,	,	,
cord-312486-rumqopg0	73	8	fibrosis	fibrosis	NN
cord-312486-rumqopg0	73	9	,	,	,
cord-312486-rumqopg0	73	10	and	and	CC
cord-312486-rumqopg0	73	11	generate	generate	VB
cord-312486-rumqopg0	73	12	vasodilation	vasodilation	NN
cord-312486-rumqopg0	73	13	.	.	.
cord-312486-rumqopg0	74	1	Further	further	RB
cord-312486-rumqopg0	74	2	,	,	,
cord-312486-rumqopg0	74	3	a	a	DT
cord-312486-rumqopg0	74	4	high	high	JJ
cord-312486-rumqopg0	74	5	ACE2	ACE2	NNP
cord-312486-rumqopg0	74	6	/	/	SYM
cord-312486-rumqopg0	74	7	ACE1	ace1	JJ
cord-312486-rumqopg0	74	8	ratio	ratio	NN
cord-312486-rumqopg0	74	9	protects	protect	VBZ
cord-312486-rumqopg0	74	10	the	the	DT
cord-312486-rumqopg0	74	11	integrity	integrity	NN
cord-312486-rumqopg0	74	12	of	of	IN
cord-312486-rumqopg0	74	13	the	the	DT
cord-312486-rumqopg0	74	14	endothelium	endothelium	NN
cord-312486-rumqopg0	74	15	and	and	CC
cord-312486-rumqopg0	74	16	promotes	promote	VBZ
cord-312486-rumqopg0	74	17	antithrombotic	antithrombotic	JJ
cord-312486-rumqopg0	74	18	activity	activity	NN
cord-312486-rumqopg0	74	19	.	.	.
cord-312486-rumqopg0	75	1	Previous	previous	JJ
cord-312486-rumqopg0	75	2	studies	study	NNS
cord-312486-rumqopg0	75	3	have	have	VBP
cord-312486-rumqopg0	75	4	found	find	VBN
cord-312486-rumqopg0	75	5	ACE2	ACE2	NNP
cord-312486-rumqopg0	75	6	playing	play	VBG
cord-312486-rumqopg0	75	7	a	a	DT
cord-312486-rumqopg0	75	8	protective	protective	JJ
cord-312486-rumqopg0	75	9	role	role	NN
cord-312486-rumqopg0	75	10	in	in	IN
cord-312486-rumqopg0	75	11	severe	severe	JJ
cord-312486-rumqopg0	75	12	lung	lung	NN
cord-312486-rumqopg0	75	13	injury	injury	NN
cord-312486-rumqopg0	75	14	in	in	IN
cord-312486-rumqopg0	75	15	ACE2	ACE2	NNP
cord-312486-rumqopg0	75	16	knockout	knockout	NN
cord-312486-rumqopg0	75	17	(	(	-LRB-
cord-312486-rumqopg0	75	18	KO	KO	NNP
cord-312486-rumqopg0	75	19	)	)	-RRB-
cord-312486-rumqopg0	75	20	mice	mouse	NNS
cord-312486-rumqopg0	75	21	[	[	-LRB-
cord-312486-rumqopg0	75	22	41	41	CD
cord-312486-rumqopg0	75	23	]	]	-RRB-
cord-312486-rumqopg0	75	24	.	.	.
cord-312486-rumqopg0	76	1	ACE2	ACE2	NNP
cord-312486-rumqopg0	76	2	KO	KO	NNP
cord-312486-rumqopg0	76	3	mice	mouse	NNS
cord-312486-rumqopg0	76	4	challenged	challenge	VBN
cord-312486-rumqopg0	76	5	with	with	IN
cord-312486-rumqopg0	76	6	avian	avian	JJ
cord-312486-rumqopg0	76	7	influenza	influenza	NN
cord-312486-rumqopg0	76	8	H5N1	H5N1	NNP
cord-312486-rumqopg0	76	9	[	[	-LRB-
cord-312486-rumqopg0	76	10	42	42	CD
cord-312486-rumqopg0	76	11	]	]	-RRB-
cord-312486-rumqopg0	76	12	or	or	CC
cord-312486-rumqopg0	76	13	H7N9	H7N9	NNP
cord-312486-rumqopg0	76	14	[	[	-LRB-
cord-312486-rumqopg0	76	15	43	43	CD
cord-312486-rumqopg0	76	16	]	]	-RRB-
cord-312486-rumqopg0	76	17	resulted	result	VBD
cord-312486-rumqopg0	76	18	in	in	IN
cord-312486-rumqopg0	76	19	severe	severe	JJ
cord-312486-rumqopg0	76	20	lung	lung	NN
cord-312486-rumqopg0	76	21	injury	injury	NN
cord-312486-rumqopg0	76	22	,	,	,
cord-312486-rumqopg0	76	23	despite	despite	IN
cord-312486-rumqopg0	76	24	that	that	DT
cord-312486-rumqopg0	76	25	ACE2	ACE2	NNP
cord-312486-rumqopg0	76	26	is	be	VBZ
cord-312486-rumqopg0	76	27	not	not	RB
cord-312486-rumqopg0	76	28	a	a	DT
cord-312486-rumqopg0	76	29	receptor	receptor	NN
cord-312486-rumqopg0	76	30	for	for	IN
cord-312486-rumqopg0	76	31	avian	avian	JJ
cord-312486-rumqopg0	76	32	influenza	influenza	NN
cord-312486-rumqopg0	76	33	.	.	.
cord-312486-rumqopg0	77	1	In	in	IN
cord-312486-rumqopg0	77	2	fact	fact	NN
cord-312486-rumqopg0	77	3	infection	infection	NN
cord-312486-rumqopg0	77	4	with	with	IN
cord-312486-rumqopg0	77	5	avian	avian	JJ
cord-312486-rumqopg0	77	6	influenza	influenza	NN
cord-312486-rumqopg0	77	7	strains	strain	NNS
cord-312486-rumqopg0	77	8	resulted	result	VBD
cord-312486-rumqopg0	77	9	in	in	IN
cord-312486-rumqopg0	77	10	downregulation	downregulation	NN
cord-312486-rumqopg0	77	11	of	of	IN
cord-312486-rumqopg0	77	12	ACE2	ACE2	NNP
cord-312486-rumqopg0	77	13	expression	expression	NN
cord-312486-rumqopg0	77	14	in	in	IN
cord-312486-rumqopg0	77	15	the	the	DT
cord-312486-rumqopg0	77	16	lung	lung	NN
cord-312486-rumqopg0	77	17	and	and	CC
cord-312486-rumqopg0	77	18	increased	increase	VBN
cord-312486-rumqopg0	77	19	serum	serum	NN
cord-312486-rumqopg0	77	20	angiotensin	angiotensin	NN
cord-312486-rumqopg0	77	21	II	II	NNP
cord-312486-rumqopg0	77	22	,	,	,
cord-312486-rumqopg0	77	23	both	both	DT
cord-312486-rumqopg0	77	24	in	in	IN
cord-312486-rumqopg0	77	25	mice	mouse	NNS
cord-312486-rumqopg0	77	26	and	and	CC
cord-312486-rumqopg0	77	27	human	human	JJ
cord-312486-rumqopg0	77	28	subjects	subject	NNS
cord-312486-rumqopg0	77	29	infected	infect	VBN
cord-312486-rumqopg0	77	30	by	by	IN
cord-312486-rumqopg0	77	31	the	the	DT
cord-312486-rumqopg0	77	32	virus	virus	NN
cord-312486-rumqopg0	77	33	[	[	-LRB-
cord-312486-rumqopg0	77	34	42	42	CD
cord-312486-rumqopg0	77	35	]	]	-RRB-
cord-312486-rumqopg0	77	36	.	.	.
cord-312486-rumqopg0	78	1	The	the	DT
cord-312486-rumqopg0	78	2	question	question	NN
cord-312486-rumqopg0	78	3	is	be	VBZ
cord-312486-rumqopg0	78	4	whether	whether	IN
cord-312486-rumqopg0	78	5	ACE2	ACE2	NNP
cord-312486-rumqopg0	78	6	expression	expression	NN
cord-312486-rumqopg0	78	7	levels	level	NNS
cord-312486-rumqopg0	78	8	are	be	VBP
cord-312486-rumqopg0	78	9	pertinent	pertinent	JJ
cord-312486-rumqopg0	78	10	to	to	IN
cord-312486-rumqopg0	78	11	SARS	SARS	NNP
cord-312486-rumqopg0	78	12	-	-	HYPH
cord-312486-rumqopg0	78	13	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	78	14	infection	infection	NN
cord-312486-rumqopg0	78	15	only	only	RB
cord-312486-rumqopg0	78	16	in	in	IN
cord-312486-rumqopg0	78	17	the	the	DT
cord-312486-rumqopg0	78	18	tissues	tissue	NNS
cord-312486-rumqopg0	78	19	relevant	relevant	JJ
cord-312486-rumqopg0	78	20	to	to	IN
cord-312486-rumqopg0	78	21	viral	viral	JJ
cord-312486-rumqopg0	78	22	entry	entry	NN
cord-312486-rumqopg0	78	23	and	and	CC
cord-312486-rumqopg0	78	24	the	the	DT
cord-312486-rumqopg0	78	25	lungs	lung	NNS
cord-312486-rumqopg0	78	26	as	as	IN
cord-312486-rumqopg0	78	27	its	-PRON-	PRP$
cord-312486-rumqopg0	78	28	major	major	JJ
cord-312486-rumqopg0	78	29	target	target	NN
cord-312486-rumqopg0	78	30	,	,	,
cord-312486-rumqopg0	78	31	[	[	-LRB-
cord-312486-rumqopg0	78	32	44	44	CD
cord-312486-rumqopg0	78	33	,	,	,
cord-312486-rumqopg0	78	34	45	45	CD
cord-312486-rumqopg0	78	35	]	]	-RRB-
cord-312486-rumqopg0	78	36	or	or	CC
cord-312486-rumqopg0	78	37	,	,	,
cord-312486-rumqopg0	78	38	given	give	VBN
cord-312486-rumqopg0	78	39	that	that	IN
cord-312486-rumqopg0	78	40	COVID-19	covid-19	NN
cord-312486-rumqopg0	78	41	in	in	IN
cord-312486-rumqopg0	78	42	its	-PRON-	PRP$
cord-312486-rumqopg0	78	43	severe	severe	JJ
cord-312486-rumqopg0	78	44	form	form	NN
cord-312486-rumqopg0	78	45	is	be	VBZ
cord-312486-rumqopg0	78	46	a	a	DT
cord-312486-rumqopg0	78	47	systemic	systemic	JJ
cord-312486-rumqopg0	78	48	disease	disease	NN
cord-312486-rumqopg0	78	49	with	with	IN
cord-312486-rumqopg0	78	50	multi	multi	JJ
cord-312486-rumqopg0	78	51	-	-	JJ
cord-312486-rumqopg0	78	52	organ	organ	JJ
cord-312486-rumqopg0	78	53	disfunction	disfunction	NN
cord-312486-rumqopg0	78	54	[	[	-LRB-
cord-312486-rumqopg0	78	55	46	46	CD
cord-312486-rumqopg0	78	56	,	,	,
cord-312486-rumqopg0	78	57	47	47	CD
cord-312486-rumqopg0	78	58	]	]	-RRB-
cord-312486-rumqopg0	78	59	,	,	,
cord-312486-rumqopg0	78	60	ACE2	ACE2	NNP
cord-312486-rumqopg0	78	61	expression	expression	NN
cord-312486-rumqopg0	78	62	levels	level	NNS
cord-312486-rumqopg0	78	63	may	may	MD
cord-312486-rumqopg0	78	64	be	be	VB
cord-312486-rumqopg0	78	65	important	important	JJ
cord-312486-rumqopg0	78	66	in	in	IN
cord-312486-rumqopg0	78	67	multiple	multiple	JJ
cord-312486-rumqopg0	78	68	organs	organ	NNS
cord-312486-rumqopg0	78	69	and	and	CC
cord-312486-rumqopg0	78	70	tissues	tissue	NNS
cord-312486-rumqopg0	78	71	other	other	JJ
cord-312486-rumqopg0	78	72	than	than	IN
cord-312486-rumqopg0	78	73	those	those	DT
cord-312486-rumqopg0	78	74	of	of	IN
cord-312486-rumqopg0	78	75	the	the	DT
cord-312486-rumqopg0	78	76	respiratory	respiratory	JJ
cord-312486-rumqopg0	78	77	system	system	NN
cord-312486-rumqopg0	78	78	.	.	.
cord-312486-rumqopg0	79	1	Relevant	relevant	JJ
cord-312486-rumqopg0	79	2	to	to	IN
cord-312486-rumqopg0	79	3	this	this	DT
cord-312486-rumqopg0	79	4	question	question	NN
cord-312486-rumqopg0	79	5	,	,	,
cord-312486-rumqopg0	79	6	lungs	lung	NNS
cord-312486-rumqopg0	79	7	do	do	VBP
cord-312486-rumqopg0	79	8	not	not	RB
cord-312486-rumqopg0	79	9	have	have	VB
cord-312486-rumqopg0	79	10	high	high	JJ
cord-312486-rumqopg0	79	11	expression	expression	NN
cord-312486-rumqopg0	79	12	levels	level	NNS
cord-312486-rumqopg0	79	13	of	of	IN
cord-312486-rumqopg0	79	14	ACE2	ACE2	NNP
cord-312486-rumqopg0	79	15	,	,	,
cord-312486-rumqopg0	79	16	and	and	CC
cord-312486-rumqopg0	79	17	relatively	relatively	RB
cord-312486-rumqopg0	79	18	few	few	JJ
cord-312486-rumqopg0	79	19	cell	cell	NN
cord-312486-rumqopg0	79	20	types	type	NNS
cord-312486-rumqopg0	79	21	express	express	VBP
cord-312486-rumqopg0	79	22	ACE2	ACE2	NNP
cord-312486-rumqopg0	79	23	in	in	IN
cord-312486-rumqopg0	79	24	the	the	DT
cord-312486-rumqopg0	79	25	lung	lung	NN
cord-312486-rumqopg0	79	26	compared	compare	VBN
cord-312486-rumqopg0	79	27	to	to	IN
cord-312486-rumqopg0	79	28	other	other	JJ
cord-312486-rumqopg0	79	29	tissues	tissue	NNS
cord-312486-rumqopg0	79	30	[	[	-LRB-
cord-312486-rumqopg0	79	31	37	37	CD
cord-312486-rumqopg0	79	32	,	,	,
cord-312486-rumqopg0	79	33	48	48	CD
cord-312486-rumqopg0	79	34	]	]	-RRB-
cord-312486-rumqopg0	79	35	.	.	.
cord-312486-rumqopg0	80	1	Assuming	assume	VBG
cord-312486-rumqopg0	80	2	the	the	DT
cord-312486-rumqopg0	80	3	importance	importance	NN
cord-312486-rumqopg0	80	4	of	of	IN
cord-312486-rumqopg0	80	5	ACE2	ACE2	NNP
cord-312486-rumqopg0	80	6	expression	expression	NN
cord-312486-rumqopg0	80	7	throughout	throughout	IN
cord-312486-rumqopg0	80	8	the	the	DT
cord-312486-rumqopg0	80	9	human	human	JJ
cord-312486-rumqopg0	80	10	organism	organism	NN
cord-312486-rumqopg0	80	11	,	,	,
cord-312486-rumqopg0	80	12	in	in	IN
cord-312486-rumqopg0	80	13	silico	silico	NN
cord-312486-rumqopg0	80	14	analyses	analysis	NNS
cord-312486-rumqopg0	80	15	have	have	VBP
cord-312486-rumqopg0	80	16	been	be	VBN
cord-312486-rumqopg0	80	17	undertaken	undertake	VBN
cord-312486-rumqopg0	80	18	through	through	IN
cord-312486-rumqopg0	80	19	integrating	integrate	VBG
cord-312486-rumqopg0	80	20	public	public	JJ
cord-312486-rumqopg0	80	21	genomics	genomic	NNS
cord-312486-rumqopg0	80	22	,	,	,
cord-312486-rumqopg0	80	23	epigenomics	epigenomics	NNP
cord-312486-rumqopg0	80	24	and	and	CC
cord-312486-rumqopg0	80	25	transcriptomics	transcriptomics	NNP
cord-312486-rumqopg0	80	26	data	datum	NNS
cord-312486-rumqopg0	80	27	in	in	IN
cord-312486-rumqopg0	80	28	multiple	multiple	JJ
cord-312486-rumqopg0	80	29	tissues	tissue	NNS
cord-312486-rumqopg0	80	30	,	,	,
cord-312486-rumqopg0	80	31	different	different	JJ
cord-312486-rumqopg0	80	32	populations	population	NNS
cord-312486-rumqopg0	80	33	,	,	,
cord-312486-rumqopg0	80	34	disease	disease	NN
cord-312486-rumqopg0	80	35	conditions	condition	NNS
cord-312486-rumqopg0	80	36	,	,	,
cord-312486-rumqopg0	80	37	and	and	CC
cord-312486-rumqopg0	80	38	age	age	NN
cord-312486-rumqopg0	80	39	as	as	RB
cord-312486-rumqopg0	80	40	well	well	RB
cord-312486-rumqopg0	80	41	as	as	IN
cord-312486-rumqopg0	80	42	sex	sex	NN
cord-312486-rumqopg0	80	43	considerations	consideration	NNS
cord-312486-rumqopg0	80	44	.	.	.
cord-312486-rumqopg0	81	1	Intriguing	intriguing	JJ
cord-312486-rumqopg0	81	2	in	in	IN
cord-312486-rumqopg0	81	3	silico	silico	NN
cord-312486-rumqopg0	81	4	findings	finding	NNS
cord-312486-rumqopg0	81	5	suggest	suggest	VBP
cord-312486-rumqopg0	81	6	that	that	IN
cord-312486-rumqopg0	81	7	East	east	JJ
cord-312486-rumqopg0	81	8	Asian	asian	JJ
cord-312486-rumqopg0	81	9	populations	population	NNS
cord-312486-rumqopg0	81	10	have	have	VBP
cord-312486-rumqopg0	81	11	higher	high	JJR
cord-312486-rumqopg0	81	12	allele	allele	NN
cord-312486-rumqopg0	81	13	frequencies	frequency	NNS
cord-312486-rumqopg0	81	14	in	in	IN
cord-312486-rumqopg0	81	15	expression	expression	NN
cord-312486-rumqopg0	81	16	quantitative	quantitative	JJ
cord-312486-rumqopg0	81	17	trait	trait	NN
cord-312486-rumqopg0	81	18	loci	locus	NNS
cord-312486-rumqopg0	81	19	(	(	-LRB-
cord-312486-rumqopg0	81	20	eQTL	eQTL	NNP
cord-312486-rumqopg0	81	21	)	)	-RRB-
cord-312486-rumqopg0	81	22	variants	variant	NNS
cord-312486-rumqopg0	81	23	associated	associate	VBN
cord-312486-rumqopg0	81	24	with	with	IN
cord-312486-rumqopg0	81	25	higher	high	JJR
cord-312486-rumqopg0	81	26	ACE2	ACE2	NNP
cord-312486-rumqopg0	81	27	tissue	tissue	NN
cord-312486-rumqopg0	81	28	expression	expression	NN
cord-312486-rumqopg0	81	29	compared	compare	VBN
cord-312486-rumqopg0	81	30	to	to	IN
cord-312486-rumqopg0	81	31	European	european	JJ
cord-312486-rumqopg0	81	32	and	and	CC
cord-312486-rumqopg0	81	33	African	african	JJ
cord-312486-rumqopg0	81	34	populations	population	NNS
cord-312486-rumqopg0	81	35	[	[	-LRB-
cord-312486-rumqopg0	81	36	37	37	CD
cord-312486-rumqopg0	81	37	,	,	,
cord-312486-rumqopg0	81	38	48	48	CD
cord-312486-rumqopg0	81	39	]	]	-RRB-
cord-312486-rumqopg0	81	40	.	.	.
cord-312486-rumqopg0	82	1	Furthermore	furthermore	RB
cord-312486-rumqopg0	82	2	,	,	,
cord-312486-rumqopg0	82	3	ACE2	ACE2	NNP
cord-312486-rumqopg0	82	4	expression	expression	NN
cord-312486-rumqopg0	82	5	increases	increase	NNS
cord-312486-rumqopg0	82	6	by	by	IN
cord-312486-rumqopg0	82	7	estrogens	estrogen	NNS
cord-312486-rumqopg0	82	8	and	and	CC
cord-312486-rumqopg0	82	9	to	to	IN
cord-312486-rumqopg0	82	10	a	a	DT
cord-312486-rumqopg0	82	11	much	much	RB
cord-312486-rumqopg0	82	12	lesser	less	JJR
cord-312486-rumqopg0	82	13	degree	degree	NN
cord-312486-rumqopg0	82	14	by	by	IN
cord-312486-rumqopg0	82	15	androgens	androgen	NNS
cord-312486-rumqopg0	82	16	,	,	,
cord-312486-rumqopg0	82	17	which	which	WDT
cord-312486-rumqopg0	82	18	possibly	possibly	RB
cord-312486-rumqopg0	82	19	explains	explain	VBZ
cord-312486-rumqopg0	82	20	the	the	DT
cord-312486-rumqopg0	82	21	higher	high	JJR
cord-312486-rumqopg0	82	22	ACE2	ACE2	NNP
cord-312486-rumqopg0	82	23	expression	expression	NN
cord-312486-rumqopg0	82	24	in	in	IN
cord-312486-rumqopg0	82	25	females	female	NNS
cord-312486-rumqopg0	82	26	[	[	-LRB-
cord-312486-rumqopg0	82	27	48	48	CD
cord-312486-rumqopg0	82	28	]	]	-RRB-
cord-312486-rumqopg0	82	29	.	.	.
cord-312486-rumqopg0	83	1	The	the	DT
cord-312486-rumqopg0	83	2	study	study	NN
cord-312486-rumqopg0	83	3	suggests	suggest	VBZ
cord-312486-rumqopg0	83	4	an	an	DT
cord-312486-rumqopg0	83	5	inverse	inverse	JJ
cord-312486-rumqopg0	83	6	age	age	NN
cord-312486-rumqopg0	83	7	-	-	HYPH
cord-312486-rumqopg0	83	8	dependent	dependent	JJ
cord-312486-rumqopg0	83	9	ACE2	ACE2	NNP
cord-312486-rumqopg0	83	10	expression	expression	NN
cord-312486-rumqopg0	83	11	in	in	IN
cord-312486-rumqopg0	83	12	both	both	DT
cord-312486-rumqopg0	83	13	males	male	NNS
cord-312486-rumqopg0	83	14	and	and	CC
cord-312486-rumqopg0	83	15	females	female	NNS
cord-312486-rumqopg0	83	16	,	,	,
cord-312486-rumqopg0	83	17	a	a	DT
cord-312486-rumqopg0	83	18	reduced	reduce	VBN
cord-312486-rumqopg0	83	19	expression	expression	NN
cord-312486-rumqopg0	83	20	in	in	IN
cord-312486-rumqopg0	83	21	type	type	NN
cord-312486-rumqopg0	83	22	2	2	CD
cord-312486-rumqopg0	83	23	diabetes	diabete	NNS
cord-312486-rumqopg0	83	24	,	,	,
cord-312486-rumqopg0	83	25	and	and	CC
cord-312486-rumqopg0	83	26	inhibition	inhibition	NN
cord-312486-rumqopg0	83	27	of	of	IN
cord-312486-rumqopg0	83	28	ACE2	ACE2	NNP
cord-312486-rumqopg0	83	29	expression	expression	NN
cord-312486-rumqopg0	83	30	by	by	IN
cord-312486-rumqopg0	83	31	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	83	32	cytokines	cytokine	NNS
cord-312486-rumqopg0	83	33	[	[	-LRB-
cord-312486-rumqopg0	83	34	48	48	CD
cord-312486-rumqopg0	83	35	]	]	-RRB-
cord-312486-rumqopg0	83	36	.	.	.
cord-312486-rumqopg0	84	1	These	these	DT
cord-312486-rumqopg0	84	2	interesting	interesting	JJ
cord-312486-rumqopg0	84	3	suggestions	suggestion	NNS
cord-312486-rumqopg0	84	4	(	(	-LRB-
cord-312486-rumqopg0	84	5	supporting	support	VBG
cord-312486-rumqopg0	84	6	a	a	DT
cord-312486-rumqopg0	84	7	protective	protective	JJ
cord-312486-rumqopg0	84	8	role	role	NN
cord-312486-rumqopg0	84	9	of	of	IN
cord-312486-rumqopg0	84	10	high	high	JJ
cord-312486-rumqopg0	84	11	ACE2	ACE2	NNP
cord-312486-rumqopg0	84	12	expression	expression	NN
cord-312486-rumqopg0	84	13	against	against	IN
cord-312486-rumqopg0	84	14	SARS	SARS	NNP
cord-312486-rumqopg0	84	15	-	-	HYPH
cord-312486-rumqopg0	84	16	CoV2	cov2	NN
cord-312486-rumqopg0	84	17	fatality	fatality	NN
cord-312486-rumqopg0	84	18	)	)	-RRB-
cord-312486-rumqopg0	84	19	need	need	VBP
cord-312486-rumqopg0	84	20	to	to	TO
cord-312486-rumqopg0	84	21	be	be	VB
cord-312486-rumqopg0	84	22	validated	validate	VBN
cord-312486-rumqopg0	84	23	by	by	IN
cord-312486-rumqopg0	84	24	clinical	clinical	JJ
cord-312486-rumqopg0	84	25	observations	observation	NNS
cord-312486-rumqopg0	84	26	,	,	,
cord-312486-rumqopg0	84	27	in	in	IN
cord-312486-rumqopg0	84	28	vivo	vivo	NN
cord-312486-rumqopg0	84	29	,	,	,
cord-312486-rumqopg0	84	30	and	and	CC
cord-312486-rumqopg0	84	31	in	in	IN
cord-312486-rumqopg0	84	32	vitro	vitro	FW
cord-312486-rumqopg0	84	33	experimentation	experimentation	NN
cord-312486-rumqopg0	84	34	.	.	.
cord-312486-rumqopg0	85	1	Until	until	IN
cord-312486-rumqopg0	85	2	such	such	JJ
cord-312486-rumqopg0	85	3	time	time	NN
cord-312486-rumqopg0	85	4	,	,	,
cord-312486-rumqopg0	85	5	the	the	DT
cord-312486-rumqopg0	85	6	functional	functional	JJ
cord-312486-rumqopg0	85	7	consequences	consequence	NNS
cord-312486-rumqopg0	85	8	of	of	IN
cord-312486-rumqopg0	85	9	ACE2	ACE2	NNP
cord-312486-rumqopg0	85	10	expression	expression	NN
cord-312486-rumqopg0	85	11	levels	level	NNS
cord-312486-rumqopg0	85	12	to	to	IN
cord-312486-rumqopg0	85	13	the	the	DT
cord-312486-rumqopg0	85	14	susceptibility	susceptibility	NN
cord-312486-rumqopg0	85	15	or	or	CC
cord-312486-rumqopg0	85	16	response	response	NN
cord-312486-rumqopg0	85	17	to	to	IN
cord-312486-rumqopg0	85	18	SARS	SARS	NNP
cord-312486-rumqopg0	85	19	-	-	HYPH
cord-312486-rumqopg0	85	20	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	85	21	remain	remain	VBP
cord-312486-rumqopg0	85	22	unclear	unclear	JJ
cord-312486-rumqopg0	85	23	[	[	-LRB-
cord-312486-rumqopg0	85	24	49	49	CD
cord-312486-rumqopg0	85	25	]	]	-RRB-
cord-312486-rumqopg0	85	26	.	.	.
cord-312486-rumqopg0	86	1	In	in	IN
cord-312486-rumqopg0	86	2	addition	addition	NN
cord-312486-rumqopg0	86	3	to	to	IN
cord-312486-rumqopg0	86	4	ACE2	ACE2	NNP
cord-312486-rumqopg0	86	5	,	,	,
cord-312486-rumqopg0	86	6	viral	viral	JJ
cord-312486-rumqopg0	86	7	entry	entry	NN
cord-312486-rumqopg0	86	8	requires	require	VBZ
cord-312486-rumqopg0	86	9	S	s	NN
cord-312486-rumqopg0	86	10	-	-	HYPH
cord-312486-rumqopg0	86	11	protein	protein	NN
cord-312486-rumqopg0	86	12	cleavage	cleavage	NN
cord-312486-rumqopg0	86	13	at	at	IN
cord-312486-rumqopg0	86	14	the	the	DT
cord-312486-rumqopg0	86	15	S1	S1	NNP
cord-312486-rumqopg0	86	16	/	/	SYM
cord-312486-rumqopg0	86	17	S2	S2	NNP
cord-312486-rumqopg0	86	18	and	and	CC
cord-312486-rumqopg0	86	19	S2	S2	NNP
cord-312486-rumqopg0	86	20	'	'	POS
cord-312486-rumqopg0	86	21	sites	site	NNS
cord-312486-rumqopg0	86	22	allowing	allow	VBG
cord-312486-rumqopg0	86	23	fusion	fusion	NN
cord-312486-rumqopg0	86	24	of	of	IN
cord-312486-rumqopg0	86	25	viral	viral	JJ
cord-312486-rumqopg0	86	26	and	and	CC
cord-312486-rumqopg0	86	27	cellular	cellular	JJ
cord-312486-rumqopg0	86	28	membranes	membrane	NNS
cord-312486-rumqopg0	86	29	by	by	IN
cord-312486-rumqopg0	86	30	host	host	NN
cord-312486-rumqopg0	86	31	proteases	protease	NNS
cord-312486-rumqopg0	86	32	.	.	.
cord-312486-rumqopg0	87	1	The	the	DT
cord-312486-rumqopg0	87	2	transmembrane	transmembrane	NN
cord-312486-rumqopg0	87	3	serine	serine	NN
cord-312486-rumqopg0	87	4	protease	protease	NN
cord-312486-rumqopg0	87	5	S2	S2	NNP
cord-312486-rumqopg0	87	6	(	(	-LRB-
cord-312486-rumqopg0	87	7	TMPRSS2	TMPRSS2	NNP
cord-312486-rumqopg0	87	8	)	)	-RRB-
cord-312486-rumqopg0	87	9	is	be	VBZ
cord-312486-rumqopg0	87	10	frequently	frequently	RB
cord-312486-rumqopg0	87	11	employed	employ	VBN
cord-312486-rumqopg0	87	12	for	for	IN
cord-312486-rumqopg0	87	13	this	this	DT
cord-312486-rumqopg0	87	14	purpose	purpose	NN
cord-312486-rumqopg0	87	15	by	by	IN
cord-312486-rumqopg0	87	16	SARS	SARS	NNP
cord-312486-rumqopg0	87	17	-	-	HYPH
cord-312486-rumqopg0	87	18	CoV-1	CoV-1	NNP
cord-312486-rumqopg0	87	19	and	and	CC
cord-312486-rumqopg0	87	20	SARS	SARS	NNP
cord-312486-rumqopg0	87	21	-	-	HYPH
cord-312486-rumqopg0	87	22	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	87	23	[	[	-LRB-
cord-312486-rumqopg0	87	24	20	20	CD
cord-312486-rumqopg0	87	25	,	,	,
cord-312486-rumqopg0	87	26	50	50	CD
cord-312486-rumqopg0	87	27	]	]	-RRB-
cord-312486-rumqopg0	87	28	,	,	,
cord-312486-rumqopg0	87	29	but	but	CC
cord-312486-rumqopg0	87	30	also	also	RB
cord-312486-rumqopg0	87	31	by	by	IN
cord-312486-rumqopg0	87	32	MERS	MERS	NNPS
cord-312486-rumqopg0	87	33	[	[	-LRB-
cord-312486-rumqopg0	87	34	51	51	CD
cord-312486-rumqopg0	87	35	]	]	-RRB-
cord-312486-rumqopg0	87	36	,	,	,
cord-312486-rumqopg0	87	37	and	and	CC
cord-312486-rumqopg0	87	38	human	human	JJ
cord-312486-rumqopg0	87	39	CoV-229E	CoV-229E	NNPS
cord-312486-rumqopg0	87	40	[	[	-LRB-
cord-312486-rumqopg0	87	41	52	52	CD
cord-312486-rumqopg0	87	42	]	]	-RRB-
cord-312486-rumqopg0	87	43	.	.	.
cord-312486-rumqopg0	88	1	The	the	DT
cord-312486-rumqopg0	88	2	functional	functional	JJ
cord-312486-rumqopg0	88	3	importance	importance	NN
cord-312486-rumqopg0	88	4	of	of	IN
cord-312486-rumqopg0	88	5	TMPRSS2	TMPRSS2	NNP
cord-312486-rumqopg0	88	6	in	in	IN
cord-312486-rumqopg0	88	7	CoV	cov	NN
cord-312486-rumqopg0	88	8	infections	infection	NNS
cord-312486-rumqopg0	88	9	was	be	VBD
cord-312486-rumqopg0	88	10	tested	test	VBN
cord-312486-rumqopg0	88	11	in	in	IN
cord-312486-rumqopg0	88	12	TMPRSS2	TMPRSS2	NNP
cord-312486-rumqopg0	88	13	KO	KO	NNP
cord-312486-rumqopg0	88	14	mice	mouse	NNS
cord-312486-rumqopg0	88	15	infected	infect	VBN
cord-312486-rumqopg0	88	16	with	with	IN
cord-312486-rumqopg0	88	17	SARS	SARS	NNP
cord-312486-rumqopg0	88	18	-	-	HYPH
cord-312486-rumqopg0	88	19	CoV-1	CoV-1	NNP
cord-312486-rumqopg0	88	20	and	and	CC
cord-312486-rumqopg0	88	21	MERS	MERS	NNP
cord-312486-rumqopg0	88	22	-	-	HYPH
cord-312486-rumqopg0	88	23	CoV.	CoV.	NNP
cord-312486-rumqopg0	89	1	Results	result	NNS
cord-312486-rumqopg0	89	2	show	show	VBP
cord-312486-rumqopg0	89	3	that	that	IN
cord-312486-rumqopg0	89	4	lack	lack	NN
cord-312486-rumqopg0	89	5	of	of	IN
cord-312486-rumqopg0	89	6	TMPTSS2	TMPTSS2	NNP
cord-312486-rumqopg0	89	7	in	in	IN
cord-312486-rumqopg0	89	8	the	the	DT
cord-312486-rumqopg0	89	9	airways	airways	NNP
cord-312486-rumqopg0	89	10	reduced	reduce	VBN
cord-312486-rumqopg0	89	11	severity	severity	NN
cord-312486-rumqopg0	89	12	of	of	IN
cord-312486-rumqopg0	89	13	lung	lung	NN
cord-312486-rumqopg0	89	14	pathology	pathology	NN
cord-312486-rumqopg0	89	15	after	after	IN
cord-312486-rumqopg0	89	16	infection	infection	NN
cord-312486-rumqopg0	89	17	by	by	IN
cord-312486-rumqopg0	89	18	SARS	SARS	NNP
cord-312486-rumqopg0	89	19	-	-	HYPH
cord-312486-rumqopg0	89	20	CoV-1	CoV-1	NNP
cord-312486-rumqopg0	89	21	and	and	CC
cord-312486-rumqopg0	89	22	MERS	MERS	NNP
cord-312486-rumqopg0	89	23	-	-	HYPH
cord-312486-rumqopg0	89	24	CoV	CoV	NNP
cord-312486-rumqopg0	89	25	,	,	,
cord-312486-rumqopg0	89	26	despite	despite	IN
cord-312486-rumqopg0	89	27	that	that	DT
cord-312486-rumqopg0	89	28	all	all	DT
cord-312486-rumqopg0	89	29	other	other	JJ
cord-312486-rumqopg0	89	30	host	host	NN
cord-312486-rumqopg0	89	31	proteases	protease	NNS
cord-312486-rumqopg0	89	32	were	be	VBD
cord-312486-rumqopg0	89	33	intact	intact	JJ
cord-312486-rumqopg0	89	34	[	[	-LRB-
cord-312486-rumqopg0	89	35	53	53	CD
cord-312486-rumqopg0	89	36	]	]	-RRB-
cord-312486-rumqopg0	89	37	.	.	.
cord-312486-rumqopg0	90	1	Apart	apart	RB
cord-312486-rumqopg0	90	2	from	from	IN
cord-312486-rumqopg0	90	3	CoV	CoV	NNP
cord-312486-rumqopg0	90	4	,	,	,
cord-312486-rumqopg0	90	5	TMPRSS2	TMPRSS2	NNP
cord-312486-rumqopg0	90	6	is	be	VBZ
cord-312486-rumqopg0	90	7	an	an	DT
cord-312486-rumqopg0	90	8	important	important	JJ
cord-312486-rumqopg0	90	9	host	host	NN
cord-312486-rumqopg0	90	10	protease	protease	NN
cord-312486-rumqopg0	90	11	for	for	IN
cord-312486-rumqopg0	90	12	influenza	influenza	NN
cord-312486-rumqopg0	90	13	viruses	virus	NNS
cord-312486-rumqopg0	90	14	,	,	,
cord-312486-rumqopg0	90	15	by	by	IN
cord-312486-rumqopg0	90	16	cleaving	cleave	VBG
cord-312486-rumqopg0	90	17	the	the	DT
cord-312486-rumqopg0	90	18	influenza	influenza	NN
cord-312486-rumqopg0	90	19	virus	virus	NN
cord-312486-rumqopg0	90	20	hemagglutinin	hemagglutinin	NN
cord-312486-rumqopg0	90	21	(	(	-LRB-
cord-312486-rumqopg0	90	22	HA	HA	NNP
cord-312486-rumqopg0	90	23	)	)	-RRB-
cord-312486-rumqopg0	90	24	molecule	molecule	NN
cord-312486-rumqopg0	90	25	[	[	-LRB-
cord-312486-rumqopg0	90	26	54	54	CD
cord-312486-rumqopg0	90	27	]	]	-RRB-
cord-312486-rumqopg0	90	28	.	.	.
cord-312486-rumqopg0	91	1	Furthermore	furthermore	RB
cord-312486-rumqopg0	91	2	,	,	,
cord-312486-rumqopg0	91	3	genetic	genetic	JJ
cord-312486-rumqopg0	91	4	variants	variant	NNS
cord-312486-rumqopg0	91	5	with	with	IN
cord-312486-rumqopg0	91	6	higher	high	JJR
cord-312486-rumqopg0	91	7	TMPRSS2	TMPRSS2	NNP
cord-312486-rumqopg0	91	8	expression	expression	NN
cord-312486-rumqopg0	91	9	increase	increase	NN
cord-312486-rumqopg0	91	10	susceptibility	susceptibility	NN
cord-312486-rumqopg0	91	11	to	to	IN
cord-312486-rumqopg0	91	12	severe	severe	JJ
cord-312486-rumqopg0	91	13	human	human	JJ
cord-312486-rumqopg0	91	14	H1N1(2009	H1N1(2009	NNP
cord-312486-rumqopg0	91	15	)	)	-RRB-
cord-312486-rumqopg0	91	16	and	and	CC
cord-312486-rumqopg0	92	1	avian	avian	JJ
cord-312486-rumqopg0	92	2	H7N9	H7N9	NNP
cord-312486-rumqopg0	92	3	influenza	influenza	NN
cord-312486-rumqopg0	92	4	[	[	-LRB-
cord-312486-rumqopg0	92	5	55	55	CD
cord-312486-rumqopg0	92	6	]	]	-RRB-
cord-312486-rumqopg0	92	7	.	.	.
cord-312486-rumqopg0	93	1	These	these	DT
cord-312486-rumqopg0	93	2	findings	finding	NNS
cord-312486-rumqopg0	93	3	,	,	,
cord-312486-rumqopg0	93	4	raise	raise	VB
cord-312486-rumqopg0	93	5	the	the	DT
cord-312486-rumqopg0	93	6	intriguing	intriguing	JJ
cord-312486-rumqopg0	93	7	question	question	NN
cord-312486-rumqopg0	93	8	whether	whether	IN
cord-312486-rumqopg0	93	9	genetic	genetic	JJ
cord-312486-rumqopg0	93	10	variants	variant	NNS
cord-312486-rumqopg0	93	11	with	with	IN
cord-312486-rumqopg0	93	12	higher	high	JJR
cord-312486-rumqopg0	93	13	TMPRSS2	TMPRSS2	NNP
cord-312486-rumqopg0	93	14	expression	expression	NN
cord-312486-rumqopg0	93	15	confer	confer	VBP
cord-312486-rumqopg0	93	16	higher	high	JJR
cord-312486-rumqopg0	93	17	risk	risk	NN
cord-312486-rumqopg0	93	18	and/or	and/or	CC
cord-312486-rumqopg0	93	19	severity	severity	NN
cord-312486-rumqopg0	93	20	of	of	IN
cord-312486-rumqopg0	93	21	SARS	SARS	NNP
cord-312486-rumqopg0	93	22	-	-	HYPH
cord-312486-rumqopg0	93	23	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	93	24	infections	infection	NNS
cord-312486-rumqopg0	93	25	.	.	.
cord-312486-rumqopg0	94	1	A	a	DT
cord-312486-rumqopg0	94	2	preliminary	preliminary	JJ
cord-312486-rumqopg0	94	3	study	study	NN
cord-312486-rumqopg0	94	4	from	from	IN
cord-312486-rumqopg0	94	5	Italy	Italy	NNP
cord-312486-rumqopg0	94	6	suggests	suggest	VBZ
cord-312486-rumqopg0	94	7	that	that	IN
cord-312486-rumqopg0	94	8	two	two	CD
cord-312486-rumqopg0	94	9	distinct	distinct	JJ
cord-312486-rumqopg0	94	10	TMPRSS2	TMPRSS2	NNP
cord-312486-rumqopg0	94	11	haplotypes	haplotype	NNS
cord-312486-rumqopg0	94	12	show	show	VBP
cord-312486-rumqopg0	94	13	significant	significant	JJ
cord-312486-rumqopg0	94	14	frequency	frequency	NN
cord-312486-rumqopg0	94	15	differences	difference	NNS
cord-312486-rumqopg0	94	16	between	between	IN
cord-312486-rumqopg0	94	17	Italian	italian	JJ
cord-312486-rumqopg0	94	18	and	and	CC
cord-312486-rumqopg0	94	19	East	east	JJ
cord-312486-rumqopg0	94	20	Asian	asian	JJ
cord-312486-rumqopg0	94	21	populations	population	NNS
cord-312486-rumqopg0	94	22	[	[	-LRB-
cord-312486-rumqopg0	94	23	56	56	CD
cord-312486-rumqopg0	94	24	]	]	-RRB-
cord-312486-rumqopg0	94	25	.	.	.
cord-312486-rumqopg0	95	1	Specifically	specifically	RB
cord-312486-rumqopg0	95	2	,	,	,
cord-312486-rumqopg0	95	3	the	the	DT
cord-312486-rumqopg0	95	4	rare	rare	JJ
cord-312486-rumqopg0	95	5	alleles	allele	NNS
cord-312486-rumqopg0	95	6	of	of	IN
cord-312486-rumqopg0	95	7	these	these	DT
cord-312486-rumqopg0	95	8	haplotypes	haplotype	NNS
cord-312486-rumqopg0	95	9	predicted	predict	VBD
cord-312486-rumqopg0	95	10	to	to	TO
cord-312486-rumqopg0	95	11	induce	induce	VB
cord-312486-rumqopg0	95	12	higher	high	JJR
cord-312486-rumqopg0	95	13	levels	level	NNS
cord-312486-rumqopg0	95	14	of	of	IN
cord-312486-rumqopg0	95	15	TMPRSS2	TMPRSS2	NNP
cord-312486-rumqopg0	95	16	,	,	,
cord-312486-rumqopg0	95	17	are	be	VBP
cord-312486-rumqopg0	95	18	more	more	RBR
cord-312486-rumqopg0	95	19	frequent	frequent	JJ
cord-312486-rumqopg0	95	20	among	among	IN
cord-312486-rumqopg0	95	21	Italians	Italians	NNPS
cord-312486-rumqopg0	95	22	.	.	.
cord-312486-rumqopg0	96	1	A	a	DT
cord-312486-rumqopg0	96	2	SNP	SNP	NNP
cord-312486-rumqopg0	96	3	belonging	belong	VBG
cord-312486-rumqopg0	96	4	to	to	IN
cord-312486-rumqopg0	96	5	one	one	CD
cord-312486-rumqopg0	96	6	of	of	IN
cord-312486-rumqopg0	96	7	the	the	DT
cord-312486-rumqopg0	96	8	haplotypes	haplotype	NNS
cord-312486-rumqopg0	96	9	is	be	VBZ
cord-312486-rumqopg0	96	10	the	the	DT
cord-312486-rumqopg0	96	11	same	same	JJ
cord-312486-rumqopg0	96	12	one	one	NN
cord-312486-rumqopg0	96	13	found	find	VBN
cord-312486-rumqopg0	96	14	to	to	TO
cord-312486-rumqopg0	96	15	be	be	VB
cord-312486-rumqopg0	96	16	associated	associate	VBN
cord-312486-rumqopg0	96	17	with	with	IN
cord-312486-rumqopg0	96	18	increased	increase	VBN
cord-312486-rumqopg0	96	19	susceptibility	susceptibility	NN
cord-312486-rumqopg0	96	20	to	to	IN
cord-312486-rumqopg0	96	21	severe	severe	JJ
cord-312486-rumqopg0	96	22	influenza	influenza	NN
cord-312486-rumqopg0	96	23	[	[	-LRB-
cord-312486-rumqopg0	96	24	55	55	CD
cord-312486-rumqopg0	96	25	]	]	-RRB-
cord-312486-rumqopg0	96	26	.	.	.
cord-312486-rumqopg0	97	1	As	as	IN
cord-312486-rumqopg0	97	2	will	will	MD
cord-312486-rumqopg0	97	3	be	be	VB
cord-312486-rumqopg0	97	4	discussed	discuss	VBN
cord-312486-rumqopg0	97	5	further	further	RB
cord-312486-rumqopg0	97	6	,	,	,
cord-312486-rumqopg0	97	7	cytokines	cytokine	NNS
cord-312486-rumqopg0	97	8	play	play	VBP
cord-312486-rumqopg0	97	9	an	an	DT
cord-312486-rumqopg0	97	10	essential	essential	JJ
cord-312486-rumqopg0	97	11	role	role	NN
cord-312486-rumqopg0	97	12	in	in	IN
cord-312486-rumqopg0	97	13	the	the	DT
cord-312486-rumqopg0	97	14	pathogenesis	pathogenesis	NN
cord-312486-rumqopg0	97	15	of	of	IN
cord-312486-rumqopg0	97	16	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	97	17	.	.	.
cord-312486-rumqopg0	98	1	While	while	IN
cord-312486-rumqopg0	98	2	environment	environment	NN
cord-312486-rumqopg0	98	3	,	,	,
cord-312486-rumqopg0	98	4	microbiome	microbiome	NN
cord-312486-rumqopg0	98	5	,	,	,
cord-312486-rumqopg0	98	6	genetics	genetics	NN
cord-312486-rumqopg0	98	7	,	,	,
cord-312486-rumqopg0	98	8	and	and	CC
cord-312486-rumqopg0	98	9	host	host	NN
cord-312486-rumqopg0	98	10	factors	factor	NNS
cord-312486-rumqopg0	98	11	,	,	,
cord-312486-rumqopg0	98	12	each	each	DT
cord-312486-rumqopg0	98	13	can	can	MD
cord-312486-rumqopg0	98	14	influence	influence	VB
cord-312486-rumqopg0	98	15	cytokine	cytokine	NN
cord-312486-rumqopg0	98	16	responses	response	NNS
cord-312486-rumqopg0	98	17	to	to	IN
cord-312486-rumqopg0	98	18	pathogen	pathogen	VB
cord-312486-rumqopg0	98	19	stimulation	stimulation	NN
cord-312486-rumqopg0	98	20	,	,	,
cord-312486-rumqopg0	98	21	genetic	genetic	JJ
cord-312486-rumqopg0	98	22	variations	variation	NNS
cord-312486-rumqopg0	98	23	appears	appear	VBZ
cord-312486-rumqopg0	98	24	to	to	TO
cord-312486-rumqopg0	98	25	be	be	VB
cord-312486-rumqopg0	98	26	a	a	DT
cord-312486-rumqopg0	98	27	main	main	JJ
cord-312486-rumqopg0	98	28	component	component	NN
cord-312486-rumqopg0	98	29	shaping	shape	VBG
cord-312486-rumqopg0	98	30	cytokine	cytokine	NN
cord-312486-rumqopg0	98	31	responses	response	NNS
cord-312486-rumqopg0	98	32	in	in	IN
cord-312486-rumqopg0	98	33	humans	human	NNS
cord-312486-rumqopg0	98	34	[	[	-LRB-
cord-312486-rumqopg0	98	35	57	57	CD
cord-312486-rumqopg0	98	36	]	]	-RRB-
cord-312486-rumqopg0	98	37	.	.	.
cord-312486-rumqopg0	99	1	For	for	IN
cord-312486-rumqopg0	99	2	perspective	perspective	NN
cord-312486-rumqopg0	99	3	,	,	,
cord-312486-rumqopg0	99	4	the	the	DT
cord-312486-rumqopg0	99	5	microbiome	microbiome	NN
cord-312486-rumqopg0	99	6	does	do	VBZ
cord-312486-rumqopg0	99	7	seem	seem	VB
cord-312486-rumqopg0	99	8	to	to	TO
cord-312486-rumqopg0	99	9	have	have	VB
cord-312486-rumqopg0	99	10	a	a	DT
cord-312486-rumqopg0	99	11	smaller	small	JJR
cord-312486-rumqopg0	99	12	impact	impact	NN
cord-312486-rumqopg0	99	13	on	on	IN
cord-312486-rumqopg0	99	14	cytokine	cytokine	NN
cord-312486-rumqopg0	99	15	production	production	NN
cord-312486-rumqopg0	99	16	capability	capability	NN
cord-312486-rumqopg0	99	17	.	.	.
cord-312486-rumqopg0	100	1	It	-PRON-	PRP
cord-312486-rumqopg0	100	2	is	be	VBZ
cord-312486-rumqopg0	100	3	estimated	estimate	VBN
cord-312486-rumqopg0	100	4	that	that	IN
cord-312486-rumqopg0	100	5	microbiome	microbiome	NN
cord-312486-rumqopg0	100	6	explain	explain	VBP
cord-312486-rumqopg0	100	7	only	only	RB
cord-312486-rumqopg0	100	8	10	10	CD
cord-312486-rumqopg0	100	9	%	%	NN
cord-312486-rumqopg0	100	10	of	of	IN
cord-312486-rumqopg0	100	11	cytokine	cytokine	NN
cord-312486-rumqopg0	100	12	production	production	NN
cord-312486-rumqopg0	100	13	[	[	-LRB-
cord-312486-rumqopg0	100	14	58	58	CD
cord-312486-rumqopg0	100	15	]	]	-RRB-
cord-312486-rumqopg0	100	16	.	.	.
cord-312486-rumqopg0	101	1	Large	large	JJ
cord-312486-rumqopg0	101	2	-	-	HYPH
cord-312486-rumqopg0	101	3	scale	scale	NN
cord-312486-rumqopg0	101	4	studies	study	NNS
cord-312486-rumqopg0	101	5	from	from	IN
cord-312486-rumqopg0	101	6	the	the	DT
cord-312486-rumqopg0	101	7	Human	Human	NNP
cord-312486-rumqopg0	101	8	Functional	Functional	NNP
cord-312486-rumqopg0	101	9	Genomics	Genomics	NNPS
cord-312486-rumqopg0	101	10	Project	Project	NNP
cord-312486-rumqopg0	101	11	[	[	-LRB-
cord-312486-rumqopg0	101	12	57	57	CD
cord-312486-rumqopg0	101	13	]	]	-RRB-
cord-312486-rumqopg0	101	14	have	have	VBP
cord-312486-rumqopg0	101	15	shown	show	VBN
cord-312486-rumqopg0	101	16	that	that	IN
cord-312486-rumqopg0	101	17	different	different	JJ
cord-312486-rumqopg0	101	18	cytokines	cytokine	NNS
cord-312486-rumqopg0	101	19	have	have	VBP
cord-312486-rumqopg0	101	20	different	different	JJ
cord-312486-rumqopg0	101	21	levels	level	NNS
cord-312486-rumqopg0	101	22	of	of	IN
cord-312486-rumqopg0	101	23	genetic	genetic	JJ
cord-312486-rumqopg0	101	24	influence	influence	NN
cord-312486-rumqopg0	101	25	.	.	.
cord-312486-rumqopg0	102	1	This	this	DT
cord-312486-rumqopg0	102	2	is	be	VBZ
cord-312486-rumqopg0	102	3	an	an	DT
cord-312486-rumqopg0	102	4	important	important	JJ
cord-312486-rumqopg0	102	5	concept	concept	NN
cord-312486-rumqopg0	102	6	for	for	IN
cord-312486-rumqopg0	102	7	host	host	NN
cord-312486-rumqopg0	102	8	defense	defense	NN
cord-312486-rumqopg0	102	9	and	and	CC
cord-312486-rumqopg0	102	10	disease	disease	NN
cord-312486-rumqopg0	102	11	,	,	,
cord-312486-rumqopg0	102	12	as	as	IN
cord-312486-rumqopg0	102	13	cytokines	cytokine	NNS
cord-312486-rumqopg0	102	14	are	be	VBP
cord-312486-rumqopg0	102	15	fundamental	fundamental	JJ
cord-312486-rumqopg0	102	16	in	in	IN
cord-312486-rumqopg0	102	17	orchestrating	orchestrate	VBG
cord-312486-rumqopg0	102	18	overall	overall	JJ
cord-312486-rumqopg0	102	19	immune	immune	JJ
cord-312486-rumqopg0	102	20	responses	response	NNS
cord-312486-rumqopg0	102	21	,	,	,
cord-312486-rumqopg0	102	22	and	and	CC
cord-312486-rumqopg0	102	23	can	can	MD
cord-312486-rumqopg0	102	24	drive	drive	VB
cord-312486-rumqopg0	102	25	pathology	pathology	NN
cord-312486-rumqopg0	102	26	when	when	WRB
cord-312486-rumqopg0	102	27	dysregulated	dysregulate	VBN
cord-312486-rumqopg0	102	28	,	,	,
cord-312486-rumqopg0	102	29	as	as	IN
cord-312486-rumqopg0	102	30	is	be	VBZ
cord-312486-rumqopg0	102	31	the	the	DT
cord-312486-rumqopg0	102	32	case	case	NN
cord-312486-rumqopg0	102	33	in	in	IN
cord-312486-rumqopg0	102	34	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	102	35	.	.	.
cord-312486-rumqopg0	103	1	Pertinent	pertinent	JJ
cord-312486-rumqopg0	103	2	to	to	IN
cord-312486-rumqopg0	103	3	the	the	DT
cord-312486-rumqopg0	103	4	present	present	JJ
cord-312486-rumqopg0	103	5	discussion	discussion	NN
cord-312486-rumqopg0	103	6	,	,	,
cord-312486-rumqopg0	103	7	the	the	DT
cord-312486-rumqopg0	103	8	IL-1/IL-6	IL-1/IL-6	NNP
cord-312486-rumqopg0	103	9	pathway	pathway	NN
cord-312486-rumqopg0	103	10	especially	especially	RB
cord-312486-rumqopg0	103	11	,	,	,
cord-312486-rumqopg0	103	12	seems	seem	VBZ
cord-312486-rumqopg0	103	13	to	to	TO
cord-312486-rumqopg0	103	14	be	be	VB
cord-312486-rumqopg0	103	15	regulated	regulate	VBN
cord-312486-rumqopg0	103	16	mainly	mainly	RB
cord-312486-rumqopg0	103	17	by	by	IN
cord-312486-rumqopg0	103	18	genetic	genetic	JJ
cord-312486-rumqopg0	103	19	factors	factor	NNS
cord-312486-rumqopg0	103	20	[	[	-LRB-
cord-312486-rumqopg0	103	21	57	57	CD
cord-312486-rumqopg0	103	22	]	]	-RRB-
cord-312486-rumqopg0	103	23	.	.	.
cord-312486-rumqopg0	104	1	My	-PRON-	PRP$
cord-312486-rumqopg0	104	2	own	own	JJ
cord-312486-rumqopg0	104	3	early	early	JJ
cord-312486-rumqopg0	104	4	work	work	NN
cord-312486-rumqopg0	104	5	,	,	,
cord-312486-rumqopg0	104	6	has	have	VBZ
cord-312486-rumqopg0	104	7	provided	provide	VBN
cord-312486-rumqopg0	104	8	evidence	evidence	NN
cord-312486-rumqopg0	104	9	for	for	IN
cord-312486-rumqopg0	104	10	the	the	DT
cord-312486-rumqopg0	104	11	heritability	heritability	NN
cord-312486-rumqopg0	104	12	of	of	IN
cord-312486-rumqopg0	104	13	TNF	TNF	NNP
cord-312486-rumqopg0	104	14	production	production	NN
cord-312486-rumqopg0	104	15	capability	capability	NN
cord-312486-rumqopg0	104	16	in	in	IN
cord-312486-rumqopg0	104	17	mouse	mouse	NN
cord-312486-rumqopg0	104	18	and	and	CC
cord-312486-rumqopg0	104	19	man	man	NN
cord-312486-rumqopg0	104	20	[	[	-LRB-
cord-312486-rumqopg0	104	21	59	59	CD
cord-312486-rumqopg0	104	22	,	,	,
cord-312486-rumqopg0	104	23	60	60	CD
cord-312486-rumqopg0	104	24	]	]	-RRB-
cord-312486-rumqopg0	104	25	.	.	.
cord-312486-rumqopg0	105	1	Notwithstanding	notwithstanding	IN
cord-312486-rumqopg0	105	2	the	the	DT
cord-312486-rumqopg0	105	3	current	current	JJ
cord-312486-rumqopg0	105	4	paucity	paucity	NN
cord-312486-rumqopg0	105	5	of	of	IN
cord-312486-rumqopg0	105	6	such	such	JJ
cord-312486-rumqopg0	105	7	studies	study	NNS
cord-312486-rumqopg0	105	8	in	in	IN
cord-312486-rumqopg0	105	9	CoV	CoV	NNP
cord-312486-rumqopg0	105	10	,	,	,
cord-312486-rumqopg0	105	11	I	-PRON-	PRP
cord-312486-rumqopg0	105	12	strongly	strongly	RB
cord-312486-rumqopg0	105	13	believe	believe	VBP
cord-312486-rumqopg0	105	14	this	this	DT
cord-312486-rumqopg0	105	15	area	area	NN
cord-312486-rumqopg0	105	16	of	of	IN
cord-312486-rumqopg0	105	17	research	research	NN
cord-312486-rumqopg0	105	18	promises	promise	NNS
cord-312486-rumqopg0	105	19	to	to	TO
cord-312486-rumqopg0	105	20	generate	generate	VB
cord-312486-rumqopg0	105	21	valuable	valuable	JJ
cord-312486-rumqopg0	105	22	information	information	NN
cord-312486-rumqopg0	105	23	as	as	IN
cord-312486-rumqopg0	105	24	for	for	IN
cord-312486-rumqopg0	105	25	the	the	DT
cord-312486-rumqopg0	105	26	pathogenesis	pathogenesis	NN
cord-312486-rumqopg0	105	27	and	and	CC
cord-312486-rumqopg0	105	28	potential	potential	JJ
cord-312486-rumqopg0	105	29	treatment	treatment	NN
cord-312486-rumqopg0	105	30	of	of	IN
cord-312486-rumqopg0	105	31	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	105	32	.	.	.
cord-312486-rumqopg0	106	1	African	African	NNP
cord-312486-rumqopg0	106	2	Americans	Americans	NNPS
cord-312486-rumqopg0	106	3	infected	infect	VBN
cord-312486-rumqopg0	106	4	with	with	IN
cord-312486-rumqopg0	106	5	SARS	SARS	NNP
cord-312486-rumqopg0	106	6	-	-	HYPH
cord-312486-rumqopg0	106	7	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	106	8	seem	seem	VBP
cord-312486-rumqopg0	106	9	to	to	TO
cord-312486-rumqopg0	106	10	be	be	VB
cord-312486-rumqopg0	106	11	at	at	IN
cord-312486-rumqopg0	106	12	a	a	DT
cord-312486-rumqopg0	106	13	greater	great	JJR
cord-312486-rumqopg0	106	14	risk	risk	NN
cord-312486-rumqopg0	106	15	for	for	IN
cord-312486-rumqopg0	106	16	severe	severe	JJ
cord-312486-rumqopg0	106	17	outcome	outcome	NN
cord-312486-rumqopg0	106	18	.	.	.
cord-312486-rumqopg0	107	1	While	while	IN
cord-312486-rumqopg0	107	2	comorbidities	comorbiditie	NNS
cord-312486-rumqopg0	107	3	and	and	CC
cord-312486-rumqopg0	107	4	socioeconomic	socioeconomic	JJ
cord-312486-rumqopg0	107	5	circumstances	circumstance	NNS
cord-312486-rumqopg0	107	6	certainly	certainly	RB
cord-312486-rumqopg0	107	7	play	play	VBP
cord-312486-rumqopg0	107	8	a	a	DT
cord-312486-rumqopg0	107	9	critical	critical	JJ
cord-312486-rumqopg0	107	10	role	role	NN
cord-312486-rumqopg0	107	11	,	,	,
cord-312486-rumqopg0	107	12	cytokines	cytokine	NNS
cord-312486-rumqopg0	107	13	may	may	MD
cord-312486-rumqopg0	107	14	have	have	VB
cord-312486-rumqopg0	107	15	an	an	DT
cord-312486-rumqopg0	107	16	important	important	JJ
cord-312486-rumqopg0	107	17	role	role	NN
cord-312486-rumqopg0	107	18	too	too	RB
cord-312486-rumqopg0	107	19	.	.	.
cord-312486-rumqopg0	108	1	A	a	DT
cord-312486-rumqopg0	108	2	preliminary	preliminary	JJ
cord-312486-rumqopg0	108	3	study	study	NN
cord-312486-rumqopg0	108	4	compared	compare	VBN
cord-312486-rumqopg0	108	5	expression	expression	NN
cord-312486-rumqopg0	108	6	levels	level	NNS
cord-312486-rumqopg0	108	7	of	of	IN
cord-312486-rumqopg0	108	8	cytokines	cytokine	NNS
cord-312486-rumqopg0	108	9	and	and	CC
cord-312486-rumqopg0	108	10	other	other	JJ
cord-312486-rumqopg0	108	11	immune	immune	JJ
cord-312486-rumqopg0	108	12	modulators	modulator	NNS
cord-312486-rumqopg0	108	13	between	between	IN
cord-312486-rumqopg0	108	14	Caucasian	caucasian	JJ
cord-312486-rumqopg0	108	15	Americans	Americans	NNPS
cord-312486-rumqopg0	108	16	and	and	CC
cord-312486-rumqopg0	108	17	African	African	NNPS
cord-312486-rumqopg0	108	18	Americans	Americans	NNPS
cord-312486-rumqopg0	108	19	using	use	VBG
cord-312486-rumqopg0	108	20	RNAseq	RNAseq	NNP
cord-312486-rumqopg0	108	21	data	data	NN
cord-312486-rumqopg0	108	22	[	[	-LRB-
cord-312486-rumqopg0	108	23	61	61	CD
cord-312486-rumqopg0	108	24	]	]	-RRB-
cord-312486-rumqopg0	108	25	.	.	.
cord-312486-rumqopg0	109	1	Results	result	NNS
cord-312486-rumqopg0	109	2	show	show	VBP
cord-312486-rumqopg0	109	3	IL-1	IL-1	NNP
cord-312486-rumqopg0	109	4	and	and	CC
cord-312486-rumqopg0	109	5	IL-18	IL-18	NNP
cord-312486-rumqopg0	109	6	receptor	receptor	NN
cord-312486-rumqopg0	109	7	1	1	CD
cord-312486-rumqopg0	109	8	(	(	-LRB-
cord-312486-rumqopg0	109	9	IL18R1	il18r1	NN
cord-312486-rumqopg0	109	10	)	)	-RRB-
cord-312486-rumqopg0	109	11	,	,	,
cord-312486-rumqopg0	109	12	IL12R1	il12r1	UH
cord-312486-rumqopg0	109	13	,	,	,
cord-312486-rumqopg0	109	14	TLR7	TLR7	NNP
cord-312486-rumqopg0	109	15	and	and	CC
cord-312486-rumqopg0	109	16	TLR9	TLR9	NNP
cord-312486-rumqopg0	109	17	were	be	VBD
cord-312486-rumqopg0	109	18	significantly	significantly	RB
cord-312486-rumqopg0	109	19	higher	high	JJR
cord-312486-rumqopg0	109	20	in	in	IN
cord-312486-rumqopg0	109	21	African	african	JJ
cord-312486-rumqopg0	109	22	Americans	Americans	NNPS
cord-312486-rumqopg0	109	23	suggesting	suggest	VBG
cord-312486-rumqopg0	109	24	perhaps	perhaps	RB
cord-312486-rumqopg0	109	25	the	the	DT
cord-312486-rumqopg0	109	26	tendency	tendency	NN
cord-312486-rumqopg0	109	27	to	to	TO
cord-312486-rumqopg0	109	28	develop	develop	VB
cord-312486-rumqopg0	109	29	higher	high	JJR
cord-312486-rumqopg0	109	30	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	109	31	cytokine	cytokine	NN
cord-312486-rumqopg0	109	32	responses	response	NNS
cord-312486-rumqopg0	109	33	.	.	.
cord-312486-rumqopg0	110	1	Much	much	RB
cord-312486-rumqopg0	110	2	more	more	JJR
cord-312486-rumqopg0	110	3	work	work	NN
cord-312486-rumqopg0	110	4	is	be	VBZ
cord-312486-rumqopg0	110	5	needed	need	VBN
cord-312486-rumqopg0	110	6	to	to	TO
cord-312486-rumqopg0	110	7	validate	validate	VB
cord-312486-rumqopg0	110	8	these	these	DT
cord-312486-rumqopg0	110	9	observations	observation	NNS
cord-312486-rumqopg0	110	10	.	.	.
cord-312486-rumqopg0	111	1	Genome	Genome	NNP
cord-312486-rumqopg0	111	2	wide	wide	JJ
cord-312486-rumqopg0	111	3	association	association	NN
cord-312486-rumqopg0	111	4	studies	study	NNS
cord-312486-rumqopg0	111	5	(	(	-LRB-
cord-312486-rumqopg0	111	6	GWAS	GWAS	NNP
cord-312486-rumqopg0	111	7	)	)	-RRB-
cord-312486-rumqopg0	111	8	allowing	allow	VBG
cord-312486-rumqopg0	111	9	the	the	DT
cord-312486-rumqopg0	111	10	unbiased	unbiased	JJ
cord-312486-rumqopg0	111	11	clustering	clustering	NN
cord-312486-rumqopg0	111	12	of	of	IN
cord-312486-rumqopg0	111	13	genetic	genetic	JJ
cord-312486-rumqopg0	111	14	variation	variation	NN
cord-312486-rumqopg0	111	15	defining	define	VBG
cord-312486-rumqopg0	111	16	human	human	JJ
cord-312486-rumqopg0	111	17	diseases	disease	NNS
cord-312486-rumqopg0	111	18	,	,	,
cord-312486-rumqopg0	111	19	require	require	VBP
cord-312486-rumqopg0	111	20	assembly	assembly	NN
cord-312486-rumqopg0	111	21	of	of	IN
cord-312486-rumqopg0	111	22	DNA	dna	NN
cord-312486-rumqopg0	111	23	samples	sample	NNS
cord-312486-rumqopg0	111	24	from	from	IN
cord-312486-rumqopg0	111	25	very	very	RB
cord-312486-rumqopg0	111	26	large	large	JJ
cord-312486-rumqopg0	111	27	number	number	NN
cord-312486-rumqopg0	111	28	of	of	IN
cord-312486-rumqopg0	111	29	subjects	subject	NNS
cord-312486-rumqopg0	111	30	which	which	WDT
cord-312486-rumqopg0	111	31	usually	usually	RB
cord-312486-rumqopg0	111	32	take	take	VBP
cord-312486-rumqopg0	111	33	a	a	DT
cord-312486-rumqopg0	111	34	long	long	JJ
cord-312486-rumqopg0	111	35	time	time	NN
cord-312486-rumqopg0	111	36	to	to	TO
cord-312486-rumqopg0	111	37	collect	collect	VB
cord-312486-rumqopg0	111	38	.	.	.
cord-312486-rumqopg0	112	1	Given	give	VBN
cord-312486-rumqopg0	112	2	that	that	IN
cord-312486-rumqopg0	112	3	we	-PRON-	PRP
cord-312486-rumqopg0	112	4	are	be	VBP
cord-312486-rumqopg0	112	5	just	just	RB
cord-312486-rumqopg0	112	6	six	six	CD
cord-312486-rumqopg0	112	7	months	month	NNS
cord-312486-rumqopg0	112	8	into	into	IN
cord-312486-rumqopg0	112	9	the	the	DT
cord-312486-rumqopg0	112	10	pandemic	pandemic	NN
cord-312486-rumqopg0	112	11	,	,	,
cord-312486-rumqopg0	112	12	it	-PRON-	PRP
cord-312486-rumqopg0	112	13	is	be	VBZ
cord-312486-rumqopg0	112	14	quite	quite	RB
cord-312486-rumqopg0	112	15	remarkable	remarkable	JJ
cord-312486-rumqopg0	112	16	that	that	IN
cord-312486-rumqopg0	112	17	a	a	DT
cord-312486-rumqopg0	112	18	medium	medium	JJ
cord-312486-rumqopg0	112	19	size	size	NN
cord-312486-rumqopg0	112	20	GWAS	GWAS	NNP
cord-312486-rumqopg0	112	21	was	be	VBD
cord-312486-rumqopg0	112	22	already	already	RB
cord-312486-rumqopg0	112	23	completed	complete	VBN
cord-312486-rumqopg0	112	24	.	.	.
cord-312486-rumqopg0	113	1	It	-PRON-	PRP
cord-312486-rumqopg0	113	2	is	be	VBZ
cord-312486-rumqopg0	113	3	the	the	DT
cord-312486-rumqopg0	113	4	first	first	JJ
cord-312486-rumqopg0	113	5	to	to	TO
cord-312486-rumqopg0	113	6	document	document	VB
cord-312486-rumqopg0	113	7	a	a	DT
cord-312486-rumqopg0	113	8	statistically	statistically	RB
cord-312486-rumqopg0	113	9	significant	significant	JJ
cord-312486-rumqopg0	113	10	association	association	NN
cord-312486-rumqopg0	113	11	between	between	IN
cord-312486-rumqopg0	113	12	genetic	genetic	JJ
cord-312486-rumqopg0	113	13	variants	variant	NNS
cord-312486-rumqopg0	113	14	and	and	CC
cord-312486-rumqopg0	113	15	severe	severe	JJ
cord-312486-rumqopg0	113	16	COVID-19	covid-19	DT
cord-312486-rumqopg0	113	17	[	[	-LRB-
cord-312486-rumqopg0	113	18	62	62	CD
cord-312486-rumqopg0	113	19	]	]	-RRB-
cord-312486-rumqopg0	113	20	.	.	.
cord-312486-rumqopg0	114	1	Variations	variation	NNS
cord-312486-rumqopg0	114	2	at	at	IN
cord-312486-rumqopg0	114	3	two	two	CD
cord-312486-rumqopg0	114	4	loci	locus	NNS
cord-312486-rumqopg0	114	5	in	in	IN
cord-312486-rumqopg0	114	6	the	the	DT
cord-312486-rumqopg0	114	7	human	human	JJ
cord-312486-rumqopg0	114	8	genome	genome	NN
cord-312486-rumqopg0	114	9	were	be	VBD
cord-312486-rumqopg0	114	10	associated	associate	VBN
cord-312486-rumqopg0	114	11	with	with	IN
cord-312486-rumqopg0	114	12	an	an	DT
cord-312486-rumqopg0	114	13	increased	increase	VBN
cord-312486-rumqopg0	114	14	risk	risk	NN
cord-312486-rumqopg0	114	15	of	of	IN
cord-312486-rumqopg0	114	16	respiratory	respiratory	JJ
cord-312486-rumqopg0	114	17	failure	failure	NN
cord-312486-rumqopg0	114	18	in	in	IN
cord-312486-rumqopg0	114	19	patients	patient	NNS
cord-312486-rumqopg0	114	20	with	with	IN
cord-312486-rumqopg0	114	21	COVID-19	covid-19	CD
cord-312486-rumqopg0	114	22	;	;	:
cord-312486-rumqopg0	114	23	one	one	CD
cord-312486-rumqopg0	114	24	,	,	,
cord-312486-rumqopg0	114	25	J	J	NNP
cord-312486-rumqopg0	114	26	o	o	NNP
cord-312486-rumqopg0	115	1	u	u	NNP
cord-312486-rumqopg0	115	2	r	r	NNP
cord-312486-rumqopg0	115	3	n	n	NN
cord-312486-rumqopg0	115	4	a	a	DT
cord-312486-rumqopg0	115	5	l	l	NN
cord-312486-rumqopg0	115	6	P	p	NN
cord-312486-rumqopg0	115	7	r	r	NN
cord-312486-rumqopg0	115	8	e	e	NN
cord-312486-rumqopg0	115	9	-p	-p	NN
cord-312486-rumqopg0	116	1	r	r	NNP
cord-312486-rumqopg0	116	2	o	o	NN
cord-312486-rumqopg0	116	3	o	o	NN
cord-312486-rumqopg0	116	4	f	f	NN
cord-312486-rumqopg0	116	5	within	within	IN
cord-312486-rumqopg0	116	6	the	the	DT
cord-312486-rumqopg0	116	7	ABO	ABO	NNP
cord-312486-rumqopg0	116	8	blood	blood	NN
cord-312486-rumqopg0	116	9	type	type	NN
cord-312486-rumqopg0	116	10	cluster	cluster	NN
cord-312486-rumqopg0	116	11	on	on	IN
cord-312486-rumqopg0	116	12	chromosome	chromosome	NN
cord-312486-rumqopg0	116	13	9	9	CD
cord-312486-rumqopg0	116	14	,	,	,
cord-312486-rumqopg0	116	15	and	and	CC
cord-312486-rumqopg0	116	16	the	the	DT
cord-312486-rumqopg0	116	17	other	other	JJ
cord-312486-rumqopg0	116	18	at	at	IN
cord-312486-rumqopg0	116	19	position	position	NN
cord-312486-rumqopg0	116	20	3p21.31	3p21.31	NNP
cord-312486-rumqopg0	116	21	.	.	.
cord-312486-rumqopg0	117	1	The	the	DT
cord-312486-rumqopg0	117	2	frequency	frequency	NN
cord-312486-rumqopg0	117	3	of	of	IN
cord-312486-rumqopg0	117	4	the	the	DT
cord-312486-rumqopg0	117	5	chromosome	chromosome	NN
cord-312486-rumqopg0	117	6	3	3	CD
cord-312486-rumqopg0	117	7	risk	risk	NN
cord-312486-rumqopg0	117	8	allele	allele	NN
cord-312486-rumqopg0	117	9	was	be	VBD
cord-312486-rumqopg0	117	10	significantly	significantly	RB
cord-312486-rumqopg0	117	11	higher	high	JJR
cord-312486-rumqopg0	117	12	in	in	IN
cord-312486-rumqopg0	117	13	those	those	DT
cord-312486-rumqopg0	117	14	patients	patient	NNS
cord-312486-rumqopg0	117	15	that	that	WDT
cord-312486-rumqopg0	117	16	needed	need	VBD
cord-312486-rumqopg0	117	17	mechanical	mechanical	JJ
cord-312486-rumqopg0	117	18	ventilation	ventilation	NN
cord-312486-rumqopg0	117	19	,	,	,
cord-312486-rumqopg0	117	20	compared	compare	VBN
cord-312486-rumqopg0	117	21	to	to	IN
cord-312486-rumqopg0	117	22	those	those	DT
cord-312486-rumqopg0	117	23	with	with	IN
cord-312486-rumqopg0	117	24	less	less	RBR
cord-312486-rumqopg0	117	25	severe	severe	JJ
cord-312486-rumqopg0	117	26	disease	disease	NN
cord-312486-rumqopg0	117	27	progress	progress	NN
cord-312486-rumqopg0	117	28	.	.	.
cord-312486-rumqopg0	118	1	Importantly	importantly	RB
cord-312486-rumqopg0	118	2	,	,	,
cord-312486-rumqopg0	118	3	this	this	DT
cord-312486-rumqopg0	118	4	locus	locus	NN
cord-312486-rumqopg0	118	5	is	be	VBZ
cord-312486-rumqopg0	118	6	home	home	NN
cord-312486-rumqopg0	118	7	to	to	IN
cord-312486-rumqopg0	118	8	six	six	CD
cord-312486-rumqopg0	118	9	genes	gene	NNS
cord-312486-rumqopg0	118	10	,	,	,
cord-312486-rumqopg0	118	11	and	and	CC
cord-312486-rumqopg0	118	12	it	-PRON-	PRP
cord-312486-rumqopg0	118	13	is	be	VBZ
cord-312486-rumqopg0	118	14	not	not	RB
cord-312486-rumqopg0	118	15	yet	yet	RB
cord-312486-rumqopg0	118	16	possible	possible	JJ
cord-312486-rumqopg0	118	17	to	to	TO
cord-312486-rumqopg0	118	18	identify	identify	VB
cord-312486-rumqopg0	118	19	which	which	WDT
cord-312486-rumqopg0	118	20	of	of	IN
cord-312486-rumqopg0	118	21	them	-PRON-	PRP
cord-312486-rumqopg0	118	22	is	be	VBZ
cord-312486-rumqopg0	118	23	responsible	responsible	JJ
cord-312486-rumqopg0	118	24	for	for	IN
cord-312486-rumqopg0	118	25	aggravating	aggravate	VBG
cord-312486-rumqopg0	118	26	the	the	DT
cord-312486-rumqopg0	118	27	disease	disease	NN
cord-312486-rumqopg0	118	28	course	course	NN
cord-312486-rumqopg0	118	29	.	.	.
cord-312486-rumqopg0	119	1	This	this	DT
cord-312486-rumqopg0	119	2	locus	locus	NN
cord-312486-rumqopg0	119	3	contains	contain	VBZ
cord-312486-rumqopg0	119	4	a	a	DT
cord-312486-rumqopg0	119	5	cluster	cluster	NN
cord-312486-rumqopg0	119	6	of	of	IN
cord-312486-rumqopg0	119	7	chemokine	chemokine	NN
cord-312486-rumqopg0	119	8	receptors	receptor	NNS
cord-312486-rumqopg0	119	9	,	,	,
cord-312486-rumqopg0	119	10	XCR1	XCR1	NNP
cord-312486-rumqopg0	119	11	,	,	,
cord-312486-rumqopg0	119	12	CCR9	CCR9	NNP
cord-312486-rumqopg0	119	13	and	and	CC
cord-312486-rumqopg0	119	14	CXCR6	CXCR6	NNP
cord-312486-rumqopg0	119	15	(	(	-LRB-
cord-312486-rumqopg0	119	16	and	and	CC
cord-312486-rumqopg0	119	17	several	several	JJ
cord-312486-rumqopg0	119	18	other	other	JJ
cord-312486-rumqopg0	119	19	cytokine	cytokine	NN
cord-312486-rumqopg0	119	20	receptor	receptor	NN
cord-312486-rumqopg0	119	21	genes	gene	NNS
cord-312486-rumqopg0	119	22	close	close	RB
cord-312486-rumqopg0	119	23	by	by	IN
cord-312486-rumqopg0	119	24	)	)	-RRB-
cord-312486-rumqopg0	119	25	,	,	,
cord-312486-rumqopg0	119	26	which	which	WDT
cord-312486-rumqopg0	119	27	have	have	VBP
cord-312486-rumqopg0	119	28	important	important	JJ
cord-312486-rumqopg0	119	29	regulatory	regulatory	JJ
cord-312486-rumqopg0	119	30	functions	function	NNS
cord-312486-rumqopg0	119	31	in	in	IN
cord-312486-rumqopg0	119	32	the	the	DT
cord-312486-rumqopg0	119	33	innate	innate	JJ
cord-312486-rumqopg0	119	34	immune	immune	JJ
cord-312486-rumqopg0	119	35	system	system	NN
cord-312486-rumqopg0	119	36	.	.	.
cord-312486-rumqopg0	120	1	Another	another	DT
cord-312486-rumqopg0	120	2	candidate	candidate	NN
cord-312486-rumqopg0	120	3	within	within	IN
cord-312486-rumqopg0	120	4	the	the	DT
cord-312486-rumqopg0	120	5	locus	locus	NN
cord-312486-rumqopg0	120	6	,	,	,
cord-312486-rumqopg0	120	7	SLCA20	SLCA20	NNP
cord-312486-rumqopg0	120	8	is	be	VBZ
cord-312486-rumqopg0	120	9	an	an	DT
cord-312486-rumqopg0	120	10	amino	amino	NN
cord-312486-rumqopg0	120	11	acid	acid	NN
cord-312486-rumqopg0	120	12	(	(	-LRB-
cord-312486-rumqopg0	120	13	proline	proline	NN
cord-312486-rumqopg0	120	14	)	)	-RRB-
cord-312486-rumqopg0	120	15	transporter	transporter	NN
cord-312486-rumqopg0	120	16	expressed	express	VBD
cord-312486-rumqopg0	120	17	at	at	IN
cord-312486-rumqopg0	120	18	luminal	luminal	JJ
cord-312486-rumqopg0	120	19	membrane	membrane	NN
cord-312486-rumqopg0	120	20	of	of	IN
cord-312486-rumqopg0	120	21	small	small	JJ
cord-312486-rumqopg0	120	22	intestine	intestine	NN
cord-312486-rumqopg0	120	23	and	and	CC
cord-312486-rumqopg0	120	24	proximal	proximal	JJ
cord-312486-rumqopg0	120	25	tubule	tubule	NN
cord-312486-rumqopg0	120	26	kidney	kidney	NN
cord-312486-rumqopg0	120	27	cells	cell	NNS
cord-312486-rumqopg0	120	28	and	and	CC
cord-312486-rumqopg0	120	29	functions	function	NNS
cord-312486-rumqopg0	120	30	in	in	IN
cord-312486-rumqopg0	120	31	absorption	absorption	NN
cord-312486-rumqopg0	120	32	of	of	IN
cord-312486-rumqopg0	120	33	proline	proline	NN
cord-312486-rumqopg0	120	34	.	.	.
cord-312486-rumqopg0	121	1	Its	-PRON-	PRP$
cord-312486-rumqopg0	121	2	expression	expression	NN
cord-312486-rumqopg0	121	3	in	in	IN
cord-312486-rumqopg0	121	4	rodent	rodent	NN
cord-312486-rumqopg0	121	5	intestine	intestine	NN
cord-312486-rumqopg0	121	6	depends	depend	VBZ
cord-312486-rumqopg0	121	7	on	on	IN
cord-312486-rumqopg0	121	8	the	the	DT
cord-312486-rumqopg0	121	9	presence	presence	NN
cord-312486-rumqopg0	121	10	of	of	IN
cord-312486-rumqopg0	121	11	ACE2	ACE2	NNP
cord-312486-rumqopg0	121	12	[	[	-LRB-
cord-312486-rumqopg0	121	13	63	63	CD
cord-312486-rumqopg0	121	14	]	]	-RRB-
cord-312486-rumqopg0	121	15	.	.	.
cord-312486-rumqopg0	122	1	However	however	RB
cord-312486-rumqopg0	122	2	,	,	,
cord-312486-rumqopg0	122	3	amino	amino	NN
cord-312486-rumqopg0	122	4	acid	acid	NN
cord-312486-rumqopg0	122	5	transporters	transporter	NNS
cord-312486-rumqopg0	122	6	have	have	VBP
cord-312486-rumqopg0	122	7	been	be	VBN
cord-312486-rumqopg0	122	8	shown	show	VBN
cord-312486-rumqopg0	122	9	to	to	TO
cord-312486-rumqopg0	122	10	induce	induce	VB
cord-312486-rumqopg0	122	11	cytokine	cytokine	JJ
cord-312486-rumqopg0	122	12	responses	response	NNS
cord-312486-rumqopg0	122	13	:	:	:
cord-312486-rumqopg0	122	14	Genetic	genetic	JJ
cord-312486-rumqopg0	122	15	variation	variation	NN
cord-312486-rumqopg0	122	16	at	at	IN
cord-312486-rumqopg0	122	17	the	the	DT
cord-312486-rumqopg0	122	18	SLC36A4	slc36a4	JJ
cord-312486-rumqopg0	122	19	amino	amino	NN
cord-312486-rumqopg0	122	20	acid	acid	NN
cord-312486-rumqopg0	122	21	transporter	transporter	NN
cord-312486-rumqopg0	122	22	show	show	VBP
cord-312486-rumqopg0	122	23	strong	strong	JJ
cord-312486-rumqopg0	122	24	association	association	NN
cord-312486-rumqopg0	122	25	with	with	IN
cord-312486-rumqopg0	122	26	pathogen	pathogen	NN
cord-312486-rumqopg0	122	27	induced	induce	VBN
cord-312486-rumqopg0	122	28	IL-22	IL-22	NNP
cord-312486-rumqopg0	122	29	production	production	NN
cord-312486-rumqopg0	122	30	[	[	-LRB-
cord-312486-rumqopg0	122	31	57	57	CD
cord-312486-rumqopg0	122	32	]	]	-RRB-
cord-312486-rumqopg0	122	33	.	.	.
cord-312486-rumqopg0	123	1	Also	also	RB
cord-312486-rumqopg0	123	2	amino	amino	NN
cord-312486-rumqopg0	123	3	-	-	HYPH
cord-312486-rumqopg0	123	4	acids	acid	NNS
cord-312486-rumqopg0	123	5	or	or	CC
cord-312486-rumqopg0	123	6	amino	amino	NN
cord-312486-rumqopg0	123	7	acid	acid	NN
cord-312486-rumqopg0	123	8	catabolites	catabolite	NNS
cord-312486-rumqopg0	123	9	have	have	VBP
cord-312486-rumqopg0	123	10	been	be	VBN
cord-312486-rumqopg0	123	11	reported	report	VBN
cord-312486-rumqopg0	123	12	to	to	TO
cord-312486-rumqopg0	123	13	modulate	modulate	VB
cord-312486-rumqopg0	123	14	cytokine	cytokine	NN
cord-312486-rumqopg0	123	15	production	production	NN
cord-312486-rumqopg0	123	16	[	[	-LRB-
cord-312486-rumqopg0	123	17	64	64	CD
cord-312486-rumqopg0	123	18	,	,	,
cord-312486-rumqopg0	123	19	65	65	CD
cord-312486-rumqopg0	123	20	]	]	-RRB-
cord-312486-rumqopg0	123	21	.	.	.
cord-312486-rumqopg0	124	1	So	so	CC
cord-312486-rumqopg0	124	2	it	-PRON-	PRP
cord-312486-rumqopg0	124	3	is	be	VBZ
cord-312486-rumqopg0	124	4	conceivable	conceivable	JJ
cord-312486-rumqopg0	124	5	that	that	IN
cord-312486-rumqopg0	124	6	SLCA20	SLCA20	NNP
cord-312486-rumqopg0	124	7	might	may	MD
cord-312486-rumqopg0	124	8	influence	influence	VB
cord-312486-rumqopg0	124	9	the	the	DT
cord-312486-rumqopg0	124	10	course	course	NN
cord-312486-rumqopg0	124	11	of	of	IN
cord-312486-rumqopg0	124	12	COVID-19	covid-19	JJ
cord-312486-rumqopg0	124	13	severity	severity	NN
cord-312486-rumqopg0	124	14	by	by	IN
cord-312486-rumqopg0	124	15	affecting	affect	VBG
cord-312486-rumqopg0	124	16	pathogen	pathogen	NN
cord-312486-rumqopg0	124	17	induced	induce	VBN
cord-312486-rumqopg0	124	18	cytokine	cytokine	NN
cord-312486-rumqopg0	124	19	production	production	NN
cord-312486-rumqopg0	124	20	,	,	,
cord-312486-rumqopg0	124	21	rather	rather	RB
cord-312486-rumqopg0	124	22	than	than	IN
cord-312486-rumqopg0	124	23	viral	viral	JJ
cord-312486-rumqopg0	124	24	entry	entry	NN
cord-312486-rumqopg0	124	25	through	through	IN
cord-312486-rumqopg0	124	26	ACE2	ACE2	NNP
cord-312486-rumqopg0	124	27	.	.	.
cord-312486-rumqopg0	125	1	In	in	IN
cord-312486-rumqopg0	125	2	this	this	DT
cord-312486-rumqopg0	125	3	respect	respect	NN
cord-312486-rumqopg0	125	4	,	,	,
cord-312486-rumqopg0	125	5	the	the	DT
cord-312486-rumqopg0	125	6	same	same	JJ
cord-312486-rumqopg0	125	7	risk	risk	NN
cord-312486-rumqopg0	125	8	SNP	SNP	NNP
cord-312486-rumqopg0	125	9	in	in	IN
cord-312486-rumqopg0	125	10	the	the	DT
cord-312486-rumqopg0	125	11	chromosome	chromosome	NN
cord-312486-rumqopg0	125	12	9	9	CD
cord-312486-rumqopg0	125	13	ABO	ABO	NNP
cord-312486-rumqopg0	125	14	blood	blood	NN
cord-312486-rumqopg0	125	15	type	type	NN
cord-312486-rumqopg0	125	16	cluster	cluster	NN
cord-312486-rumqopg0	125	17	that	that	WDT
cord-312486-rumqopg0	125	18	affects	affect	VBZ
cord-312486-rumqopg0	125	19	COVID-19	covid-19	JJ
cord-312486-rumqopg0	125	20	severity	severity	NN
cord-312486-rumqopg0	125	21	has	have	VBZ
cord-312486-rumqopg0	125	22	been	be	VBN
cord-312486-rumqopg0	125	23	associated	associate	VBN
cord-312486-rumqopg0	125	24	with	with	IN
cord-312486-rumqopg0	125	25	elevated	elevated	JJ
cord-312486-rumqopg0	125	26	IL-6	IL-6	NNP
cord-312486-rumqopg0	125	27	levels	level	NNS
cord-312486-rumqopg0	125	28	in	in	IN
cord-312486-rumqopg0	125	29	childhood	childhood	NN
cord-312486-rumqopg0	125	30	obesity	obesity	NN
cord-312486-rumqopg0	125	31	in	in	IN
cord-312486-rumqopg0	125	32	a	a	DT
cord-312486-rumqopg0	125	33	previous	previous	JJ
cord-312486-rumqopg0	125	34	GWAS	GWAS	NNP
cord-312486-rumqopg0	125	35	,	,	,
cord-312486-rumqopg0	125	36	thus	thus	RB
cord-312486-rumqopg0	125	37	,	,	,
cord-312486-rumqopg0	125	38	possibly	possibly	RB
cord-312486-rumqopg0	125	39	linking	link	VBG
cord-312486-rumqopg0	125	40	this	this	DT
cord-312486-rumqopg0	125	41	genetic	genetic	JJ
cord-312486-rumqopg0	125	42	allele	allele	NN
cord-312486-rumqopg0	125	43	with	with	IN
cord-312486-rumqopg0	125	44	elevated	elevated	JJ
cord-312486-rumqopg0	125	45	IL-6	IL-6	NNP
cord-312486-rumqopg0	125	46	levels	level	NNS
cord-312486-rumqopg0	125	47	(	(	-LRB-
cord-312486-rumqopg0	125	48	with	with	IN
cord-312486-rumqopg0	125	49	or	or	CC
cord-312486-rumqopg0	125	50	without	without	IN
cord-312486-rumqopg0	125	51	full	full	RB
cord-312486-rumqopg0	125	52	-	-	HYPH
cord-312486-rumqopg0	125	53	blown	blown	JJ
cord-312486-rumqopg0	125	54	‗cytokine	‗cytokine	NN
cord-312486-rumqopg0	125	55	storm	storm	NN
cord-312486-rumqopg0	125	56	'	'	''
cord-312486-rumqopg0	125	57	)	)	-RRB-
cord-312486-rumqopg0	125	58	described	describe	VBN
cord-312486-rumqopg0	125	59	in	in	IN
cord-312486-rumqopg0	125	60	severe	severe	JJ
cord-312486-rumqopg0	125	61	COVID-19	covid-19	JJ
cord-312486-rumqopg0	125	62	patients	patient	NNS
cord-312486-rumqopg0	125	63	.	.	.
cord-312486-rumqopg0	126	1	The	the	DT
cord-312486-rumqopg0	126	2	study	study	NN
cord-312486-rumqopg0	126	3	[	[	-LRB-
cord-312486-rumqopg0	126	4	62	62	CD
cord-312486-rumqopg0	126	5	]	]	-RRB-
cord-312486-rumqopg0	126	6	is	be	VBZ
cord-312486-rumqopg0	126	7	equally	equally	RB
cord-312486-rumqopg0	126	8	striking	striking	JJ
cord-312486-rumqopg0	126	9	for	for	IN
cord-312486-rumqopg0	126	10	the	the	DT
cord-312486-rumqopg0	126	11	genes	gene	NNS
cord-312486-rumqopg0	126	12	that	that	WDT
cord-312486-rumqopg0	126	13	failed	fail	VBD
cord-312486-rumqopg0	126	14	to	to	TO
cord-312486-rumqopg0	126	15	turn	turn	VB
cord-312486-rumqopg0	126	16	up	up	RP
cord-312486-rumqopg0	126	17	.	.	.
cord-312486-rumqopg0	127	1	Pathogen	pathogen	NN
cord-312486-rumqopg0	127	2	microorganisms	microorganism	NNS
cord-312486-rumqopg0	127	3	,	,	,
cord-312486-rumqopg0	127	4	including	include	VBG
cord-312486-rumqopg0	127	5	several	several	JJ
cord-312486-rumqopg0	127	6	viral	viral	JJ
cord-312486-rumqopg0	127	7	infections	infection	NNS
cord-312486-rumqopg0	127	8	,	,	,
cord-312486-rumqopg0	127	9	are	be	VBP
cord-312486-rumqopg0	127	10	controlled	control	VBN
cord-312486-rumqopg0	127	11	by	by	IN
cord-312486-rumqopg0	127	12	genetic	genetic	JJ
cord-312486-rumqopg0	127	13	variations	variation	NNS
cord-312486-rumqopg0	127	14	at	at	IN
cord-312486-rumqopg0	127	15	the	the	DT
cord-312486-rumqopg0	127	16	HLA	HLA	NNP
cord-312486-rumqopg0	127	17	complex	complex	NN
cord-312486-rumqopg0	127	18	at	at	IN
cord-312486-rumqopg0	127	19	chromosome	chromosome	NN
cord-312486-rumqopg0	127	20	6p21	6p21	CD
cord-312486-rumqopg0	127	21	[	[	-LRB-
cord-312486-rumqopg0	127	22	66	66	CD
cord-312486-rumqopg0	127	23	,	,	,
cord-312486-rumqopg0	127	24	67	67	CD
cord-312486-rumqopg0	127	25	]	]	-RRB-
cord-312486-rumqopg0	127	26	.	.	.
cord-312486-rumqopg0	128	1	The	the	DT
cord-312486-rumqopg0	128	2	class	class	NN
cord-312486-rumqopg0	128	3	I	i	NN
cord-312486-rumqopg0	128	4	and	and	CC
cord-312486-rumqopg0	128	5	class	class	NN
cord-312486-rumqopg0	128	6	II	II	NNP
cord-312486-rumqopg0	128	7	gene	gene	NN
cord-312486-rumqopg0	128	8	products	product	NNS
cord-312486-rumqopg0	128	9	of	of	IN
cord-312486-rumqopg0	128	10	the	the	DT
cord-312486-rumqopg0	128	11	HLA	HLA	NNP
cord-312486-rumqopg0	128	12	are	be	VBP
cord-312486-rumqopg0	128	13	involved	involve	VBN
cord-312486-rumqopg0	128	14	in	in	IN
cord-312486-rumqopg0	128	15	antigen	antigen	NN
cord-312486-rumqopg0	128	16	presentation	presentation	NN
cord-312486-rumqopg0	128	17	,	,	,
cord-312486-rumqopg0	128	18	a	a	DT
cord-312486-rumqopg0	128	19	mandatory	mandatory	JJ
cord-312486-rumqopg0	128	20	process	process	NN
cord-312486-rumqopg0	128	21	to	to	TO
cord-312486-rumqopg0	128	22	initiate	initiate	VB
cord-312486-rumqopg0	128	23	an	an	DT
cord-312486-rumqopg0	128	24	adaptive	adaptive	JJ
cord-312486-rumqopg0	128	25	immune	immune	JJ
cord-312486-rumqopg0	128	26	response	response	NN
cord-312486-rumqopg0	128	27	geared	gear	VBN
cord-312486-rumqopg0	128	28	to	to	TO
cord-312486-rumqopg0	128	29	restrain	restrain	VB
cord-312486-rumqopg0	128	30	a	a	DT
cord-312486-rumqopg0	128	31	pathogen	pathogen	NN
cord-312486-rumqopg0	128	32	.	.	.
cord-312486-rumqopg0	129	1	But	but	CC
cord-312486-rumqopg0	129	2	genetic	genetic	JJ
cord-312486-rumqopg0	129	3	variants	variant	NNS
cord-312486-rumqopg0	129	4	at	at	IN
cord-312486-rumqopg0	129	5	the	the	DT
cord-312486-rumqopg0	129	6	HLA	HLA	NNP
cord-312486-rumqopg0	129	7	region	region	NN
cord-312486-rumqopg0	129	8	did	do	VBD
cord-312486-rumqopg0	129	9	not	not	RB
cord-312486-rumqopg0	129	10	appear	appear	VB
cord-312486-rumqopg0	129	11	to	to	TO
cord-312486-rumqopg0	129	12	make	make	VB
cord-312486-rumqopg0	129	13	a	a	DT
cord-312486-rumqopg0	129	14	difference	difference	NN
cord-312486-rumqopg0	129	15	in	in	IN
cord-312486-rumqopg0	129	16	the	the	DT
cord-312486-rumqopg0	129	17	risk	risk	NN
cord-312486-rumqopg0	129	18	of	of	IN
cord-312486-rumqopg0	129	19	severe	severe	JJ
cord-312486-rumqopg0	129	20	COVID-19	covid-19	NN
cord-312486-rumqopg0	129	21	.	.	.
cord-312486-rumqopg0	130	1	Thus	thus	RB
cord-312486-rumqopg0	130	2	,	,	,
cord-312486-rumqopg0	130	3	the	the	DT
cord-312486-rumqopg0	130	4	so	so	RB
cord-312486-rumqopg0	130	5	called	call	VBN
cord-312486-rumqopg0	130	6	‗adaptive	‗adaptive	''
cord-312486-rumqopg0	130	7	'	'	``
cord-312486-rumqopg0	130	8	arm	arm	NN
cord-312486-rumqopg0	130	9	of	of	IN
cord-312486-rumqopg0	130	10	the	the	DT
cord-312486-rumqopg0	130	11	immune	immune	JJ
cord-312486-rumqopg0	130	12	system	system	NN
cord-312486-rumqopg0	130	13	seems	seem	VBZ
cord-312486-rumqopg0	130	14	to	to	TO
cord-312486-rumqopg0	130	15	be	be	VB
cord-312486-rumqopg0	130	16	less	less	RBR
cord-312486-rumqopg0	130	17	relevant	relevant	JJ
cord-312486-rumqopg0	130	18	to	to	IN
cord-312486-rumqopg0	130	19	COVID-19	covid-19	VB
cord-312486-rumqopg0	130	20	than	than	IN
cord-312486-rumqopg0	130	21	the	the	DT
cord-312486-rumqopg0	130	22	‗innate	‗innate	NN
cord-312486-rumqopg0	130	23	'	'	``
cord-312486-rumqopg0	130	24	immune	immune	JJ
cord-312486-rumqopg0	130	25	response	response	NN
cord-312486-rumqopg0	130	26	.	.	.
cord-312486-rumqopg0	131	1	I	-PRON-	PRP
cord-312486-rumqopg0	131	2	have	have	VBP
cord-312486-rumqopg0	131	3	offered	offer	VBN
cord-312486-rumqopg0	131	4	here	here	RB
cord-312486-rumqopg0	131	5	a	a	DT
cord-312486-rumqopg0	131	6	hypothesis	hypothesis	NN
cord-312486-rumqopg0	131	7	for	for	IN
cord-312486-rumqopg0	131	8	what	what	WP
cord-312486-rumqopg0	131	9	these	these	DT
cord-312486-rumqopg0	131	10	genetic	genetic	JJ
cord-312486-rumqopg0	131	11	associations	association	NNS
cord-312486-rumqopg0	131	12	might	may	MD
cord-312486-rumqopg0	131	13	actually	actually	RB
cord-312486-rumqopg0	131	14	mean	mean	VB
cord-312486-rumqopg0	131	15	.	.	.
cord-312486-rumqopg0	132	1	If	if	IN
cord-312486-rumqopg0	132	2	correct	correct	JJ
cord-312486-rumqopg0	132	3	it	-PRON-	PRP
cord-312486-rumqopg0	132	4	has	have	VBZ
cord-312486-rumqopg0	132	5	major	major	JJ
cord-312486-rumqopg0	132	6	mechanistic	mechanistic	JJ
cord-312486-rumqopg0	132	7	implication	implication	NN
cord-312486-rumqopg0	132	8	as	as	IN
cord-312486-rumqopg0	132	9	for	for	IN
cord-312486-rumqopg0	132	10	the	the	DT
cord-312486-rumqopg0	132	11	pathogenesis	pathogenesis	NN
cord-312486-rumqopg0	132	12	.	.	.
cord-312486-rumqopg0	133	1	At	at	IN
cord-312486-rumqopg0	133	2	minimum	minimum	NN
cord-312486-rumqopg0	133	3	it	-PRON-	PRP
cord-312486-rumqopg0	133	4	suggests	suggest	VBZ
cord-312486-rumqopg0	133	5	avenues	avenue	NNS
cord-312486-rumqopg0	133	6	for	for	IN
cord-312486-rumqopg0	133	7	further	further	JJ
cord-312486-rumqopg0	133	8	studies	study	NNS
cord-312486-rumqopg0	133	9	.	.	.
cord-312486-rumqopg0	134	1	Recognition	recognition	NN
cord-312486-rumqopg0	134	2	of	of	IN
cord-312486-rumqopg0	134	3	a	a	DT
cord-312486-rumqopg0	134	4	pathogen	pathogen	NN
cord-312486-rumqopg0	134	5	by	by	IN
cord-312486-rumqopg0	134	6	the	the	DT
cord-312486-rumqopg0	134	7	innate	innate	JJ
cord-312486-rumqopg0	134	8	immune	immune	JJ
cord-312486-rumqopg0	134	9	system	system	NN
cord-312486-rumqopg0	134	10	triggers	trigger	VBZ
cord-312486-rumqopg0	134	11	the	the	DT
cord-312486-rumqopg0	134	12	secretion	secretion	NN
cord-312486-rumqopg0	134	13	of	of	IN
cord-312486-rumqopg0	134	14	the	the	DT
cord-312486-rumqopg0	134	15	crucially	crucially	RB
cord-312486-rumqopg0	134	16	important	important	JJ
cord-312486-rumqopg0	134	17	type	type	NN
cord-312486-rumqopg0	134	18	I	I	NNP
cord-312486-rumqopg0	134	19	/	/	SYM
cord-312486-rumqopg0	134	20	III	iii	CD
cord-312486-rumqopg0	134	21	interferons	interferon	NNS
cord-312486-rumqopg0	134	22	(	(	-LRB-
cord-312486-rumqopg0	134	23	IFN	IFN	NNP
cord-312486-rumqopg0	134	24	)	)	-RRB-
cord-312486-rumqopg0	134	25	.	.	.
cord-312486-rumqopg0	135	1	The	the	DT
cord-312486-rumqopg0	135	2	result	result	NN
cord-312486-rumqopg0	135	3	of	of	IN
cord-312486-rumqopg0	135	4	IFN	IFN	NNP
cord-312486-rumqopg0	135	5	signaling	signal	VBG
cord-312486-rumqopg0	135	6	is	be	VBZ
cord-312486-rumqopg0	135	7	the	the	DT
cord-312486-rumqopg0	135	8	activation	activation	NN
cord-312486-rumqopg0	135	9	of	of	IN
cord-312486-rumqopg0	135	10	an	an	DT
cord-312486-rumqopg0	135	11	entire	entire	JJ
cord-312486-rumqopg0	135	12	cascade	cascade	NN
cord-312486-rumqopg0	135	13	of	of	IN
cord-312486-rumqopg0	135	14	events	event	NNS
cord-312486-rumqopg0	135	15	that	that	WDT
cord-312486-rumqopg0	135	16	include	include	VBP
cord-312486-rumqopg0	135	17	the	the	DT
cord-312486-rumqopg0	135	18	release	release	NN
cord-312486-rumqopg0	135	19	of	of	IN
cord-312486-rumqopg0	135	20	proinflammatory	proinflammatory	JJ
cord-312486-rumqopg0	135	21	cytokines	cytokine	NNS
cord-312486-rumqopg0	135	22	which	which	WDT
cord-312486-rumqopg0	135	23	further	further	RB
cord-312486-rumqopg0	135	24	signal	signal	NN
cord-312486-rumqopg0	135	25	to	to	IN
cord-312486-rumqopg0	135	26	endothelial	endothelial	JJ
cord-312486-rumqopg0	135	27	cells	cell	NNS
cord-312486-rumqopg0	135	28	,	,	,
cord-312486-rumqopg0	135	29	which	which	WDT
cord-312486-rumqopg0	135	30	then	then	RB
cord-312486-rumqopg0	135	31	enable	enable	VBP
cord-312486-rumqopg0	135	32	chemokines	chemokine	NNS
cord-312486-rumqopg0	135	33	to	to	TO
cord-312486-rumqopg0	135	34	spread	spread	VB
cord-312486-rumqopg0	135	35	throughout	throughout	IN
cord-312486-rumqopg0	135	36	the	the	DT
cord-312486-rumqopg0	135	37	blood	blood	NN
cord-312486-rumqopg0	135	38	to	to	TO
cord-312486-rumqopg0	135	39	recruit	recruit	VB
cord-312486-rumqopg0	135	40	innate	innate	JJ
cord-312486-rumqopg0	135	41	immune	immune	JJ
cord-312486-rumqopg0	135	42	cells	cell	NNS
cord-312486-rumqopg0	135	43	to	to	IN
cord-312486-rumqopg0	135	44	the	the	DT
cord-312486-rumqopg0	135	45	site	site	NN
cord-312486-rumqopg0	135	46	of	of	IN
cord-312486-rumqopg0	135	47	infection	infection	NN
cord-312486-rumqopg0	135	48	.	.	.
cord-312486-rumqopg0	136	1	The	the	DT
cord-312486-rumqopg0	136	2	recruited	recruit	VBN
cord-312486-rumqopg0	136	3	NK	NK	NNP
cord-312486-rumqopg0	136	4	cells	cell	NNS
cord-312486-rumqopg0	136	5	,	,	,
cord-312486-rumqopg0	136	6	monocytes	monocyte	NNS
cord-312486-rumqopg0	136	7	,	,	,
cord-312486-rumqopg0	136	8	and	and	CC
cord-312486-rumqopg0	136	9	neutrophils	neutrophil	NNS
cord-312486-rumqopg0	136	10	interact	interact	VBP
cord-312486-rumqopg0	136	11	with	with	IN
cord-312486-rumqopg0	136	12	activated	activate	VBN
cord-312486-rumqopg0	136	13	endothelium	endothelium	NN
cord-312486-rumqopg0	136	14	to	to	TO
cord-312486-rumqopg0	136	15	leave	leave	VB
cord-312486-rumqopg0	136	16	the	the	DT
cord-312486-rumqopg0	136	17	blood	blood	NN
cord-312486-rumqopg0	136	18	stream	stream	NN
cord-312486-rumqopg0	136	19	and	and	CC
cord-312486-rumqopg0	136	20	migrate	migrate	VB
cord-312486-rumqopg0	136	21	toward	toward	IN
cord-312486-rumqopg0	136	22	the	the	DT
cord-312486-rumqopg0	136	23	site	site	NN
cord-312486-rumqopg0	136	24	of	of	IN
cord-312486-rumqopg0	136	25	infection	infection	NN
cord-312486-rumqopg0	136	26	.	.	.
cord-312486-rumqopg0	137	1	At	at	IN
cord-312486-rumqopg0	137	2	the	the	DT
cord-312486-rumqopg0	137	3	site	site	NN
cord-312486-rumqopg0	137	4	of	of	IN
cord-312486-rumqopg0	137	5	infection	infection	NN
cord-312486-rumqopg0	137	6	they	-PRON-	PRP
cord-312486-rumqopg0	137	7	can	can	MD
cord-312486-rumqopg0	137	8	perform	perform	VB
cord-312486-rumqopg0	137	9	effector	effector	NN
cord-312486-rumqopg0	137	10	functions	function	NNS
cord-312486-rumqopg0	137	11	to	to	TO
cord-312486-rumqopg0	137	12	control	control	VB
cord-312486-rumqopg0	137	13	infections	infection	NNS
cord-312486-rumqopg0	137	14	,	,	,
cord-312486-rumqopg0	137	15	such	such	JJ
cord-312486-rumqopg0	137	16	as	as	IN
cord-312486-rumqopg0	137	17	release	release	NN
cord-312486-rumqopg0	137	18	of	of	IN
cord-312486-rumqopg0	137	19	reactive	reactive	JJ
cord-312486-rumqopg0	137	20	oxygen	oxygen	NN
cord-312486-rumqopg0	137	21	species	specie	NNS
cord-312486-rumqopg0	137	22	(	(	-LRB-
cord-312486-rumqopg0	137	23	ROS	ROS	NNP
cord-312486-rumqopg0	137	24	)	)	-RRB-
cord-312486-rumqopg0	137	25	and	and	CC
cord-312486-rumqopg0	137	26	,	,	,
cord-312486-rumqopg0	137	27	where	where	WRB
cord-312486-rumqopg0	137	28	they	-PRON-	PRP
cord-312486-rumqopg0	137	29	can	can	MD
cord-312486-rumqopg0	137	30	perform	perform	VB
cord-312486-rumqopg0	137	31	effector	effector	NN
cord-312486-rumqopg0	137	32	functions	function	NNS
cord-312486-rumqopg0	137	33	to	to	TO
cord-312486-rumqopg0	137	34	control	control	VB
cord-312486-rumqopg0	137	35	infections	infection	NNS
cord-312486-rumqopg0	137	36	,	,	,
cord-312486-rumqopg0	137	37	such	such	JJ
cord-312486-rumqopg0	137	38	as	as	IN
cord-312486-rumqopg0	137	39	release	release	NN
cord-312486-rumqopg0	137	40	of	of	IN
cord-312486-rumqopg0	137	41	reactive	reactive	JJ
cord-312486-rumqopg0	137	42	oxygen	oxygen	NN
cord-312486-rumqopg0	137	43	species	specie	NNS
cord-312486-rumqopg0	137	44	(	(	-LRB-
cord-312486-rumqopg0	137	45	ROS	ROS	NNP
cord-312486-rumqopg0	137	46	)	)	-RRB-
cord-312486-rumqopg0	137	47	and	and	CC
cord-312486-rumqopg0	137	48	directly	directly	RB
cord-312486-rumqopg0	137	49	killing	kill	VBG
cord-312486-rumqopg0	137	50	infected	infected	JJ
cord-312486-rumqopg0	137	51	cells	cell	NNS
cord-312486-rumqopg0	137	52	,	,	,
cord-312486-rumqopg0	137	53	as	as	RB
cord-312486-rumqopg0	137	54	well	well	RB
cord-312486-rumqopg0	137	55	activating	activate	VBG
cord-312486-rumqopg0	137	56	a	a	DT
cord-312486-rumqopg0	137	57	pathogen	pathogen	NN
cord-312486-rumqopg0	137	58	specific	specific	JJ
cord-312486-rumqopg0	137	59	adaptive	adaptive	JJ
cord-312486-rumqopg0	137	60	immune	immune	JJ
cord-312486-rumqopg0	137	61	response	response	NN
cord-312486-rumqopg0	137	62	.	.	.
cord-312486-rumqopg0	138	1	Given	give	VBN
cord-312486-rumqopg0	138	2	the	the	DT
cord-312486-rumqopg0	138	3	shared	share	VBN
cord-312486-rumqopg0	138	4	sequence	sequence	NN
cord-312486-rumqopg0	138	5	homology	homology	NN
cord-312486-rumqopg0	138	6	,	,	,
cord-312486-rumqopg0	138	7	the	the	DT
cord-312486-rumqopg0	138	8	virus	virus	NN
cord-312486-rumqopg0	138	9	-	-	HYPH
cord-312486-rumqopg0	138	10	host	host	NN
cord-312486-rumqopg0	138	11	interactions	interaction	NNS
cord-312486-rumqopg0	138	12	of	of	IN
cord-312486-rumqopg0	138	13	SARS	SARS	NNP
cord-312486-rumqopg0	138	14	-	-	HYPH
cord-312486-rumqopg0	138	15	Cov-2	Cov-2	NNP
cord-312486-rumqopg0	138	16	is	be	VBZ
cord-312486-rumqopg0	138	17	likely	likely	JJ
cord-312486-rumqopg0	138	18	to	to	TO
cord-312486-rumqopg0	138	19	be	be	VB
cord-312486-rumqopg0	138	20	analogous	analogous	JJ
cord-312486-rumqopg0	138	21	to	to	IN
cord-312486-rumqopg0	138	22	those	those	DT
cord-312486-rumqopg0	138	23	involving	involve	VBG
cord-312486-rumqopg0	138	24	other	other	JJ
cord-312486-rumqopg0	138	25	CoV.	CoV.	NNP
cord-312486-rumqopg0	139	1	However	however	RB
cord-312486-rumqopg0	139	2	,	,	,
cord-312486-rumqopg0	139	3	these	these	DT
cord-312486-rumqopg0	139	4	interactions	interaction	NNS
cord-312486-rumqopg0	139	5	might	may	MD
cord-312486-rumqopg0	139	6	be	be	VB
cord-312486-rumqopg0	139	7	similar	similar	JJ
cord-312486-rumqopg0	139	8	to	to	IN
cord-312486-rumqopg0	139	9	J	J	NNP
cord-312486-rumqopg0	139	10	o	o	NN
cord-312486-rumqopg0	139	11	u	u	NN
cord-312486-rumqopg0	139	12	r	r	NN
cord-312486-rumqopg0	139	13	n	n	NN
cord-312486-rumqopg0	139	14	a	a	DT
cord-312486-rumqopg0	139	15	l	l	NN
cord-312486-rumqopg0	139	16	P	p	NN
cord-312486-rumqopg0	139	17	r	r	NN
cord-312486-rumqopg0	139	18	e	e	NN
cord-312486-rumqopg0	139	19	-p	-p	NN
cord-312486-rumqopg0	139	20	r	r	NN
cord-312486-rumqopg0	139	21	o	o	NN
cord-312486-rumqopg0	139	22	o	o	NN
cord-312486-rumqopg0	139	23	f	f	NN
cord-312486-rumqopg0	139	24	other	other	JJ
cord-312486-rumqopg0	139	25	non	non	JJ
cord-312486-rumqopg0	139	26	-	-	JJ
cord-312486-rumqopg0	139	27	CoV	cov	JJ
cord-312486-rumqopg0	139	28	viruses	virus	NNS
cord-312486-rumqopg0	139	29	as	as	RB
cord-312486-rumqopg0	139	30	well	well	RB
cord-312486-rumqopg0	139	31	because	because	IN
cord-312486-rumqopg0	139	32	of	of	IN
cord-312486-rumqopg0	139	33	limited	limited	JJ
cord-312486-rumqopg0	139	34	repertoire	repertoire	NN
cord-312486-rumqopg0	139	35	and	and	CC
cord-312486-rumqopg0	139	36	conserved	conserve	VBN
cord-312486-rumqopg0	139	37	mechanisms	mechanism	NNS
cord-312486-rumqopg0	139	38	of	of	IN
cord-312486-rumqopg0	139	39	innate	innate	JJ
cord-312486-rumqopg0	139	40	immune	immune	JJ
cord-312486-rumqopg0	139	41	signaling	signaling	NN
cord-312486-rumqopg0	139	42	.	.	.
cord-312486-rumqopg0	140	1	SARS	SARS	NNP
cord-312486-rumqopg0	140	2	-	-	HYPH
cord-312486-rumqopg0	140	3	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	140	4	engages	engage	VBZ
cord-312486-rumqopg0	140	5	host	host	NN
cord-312486-rumqopg0	140	6	pattern	pattern	NN
cord-312486-rumqopg0	140	7	recognition	recognition	NN
cord-312486-rumqopg0	140	8	receptors	receptor	NNS
cord-312486-rumqopg0	140	9	(	(	-LRB-
cord-312486-rumqopg0	140	10	PRR	PRR	NNP
cord-312486-rumqopg0	140	11	)	)	-RRB-
cord-312486-rumqopg0	140	12	,	,	,
cord-312486-rumqopg0	140	13	and	and	CC
cord-312486-rumqopg0	140	14	toll	toll	NN
cord-312486-rumqopg0	140	15	-	-	HYPH
cord-312486-rumqopg0	140	16	like	like	JJ
cord-312486-rumqopg0	140	17	receptors	receptor	NNS
cord-312486-rumqopg0	140	18	(	(	-LRB-
cord-312486-rumqopg0	140	19	TLR	TLR	NNP
cord-312486-rumqopg0	140	20	)	)	-RRB-
cord-312486-rumqopg0	140	21	which	which	WDT
cord-312486-rumqopg0	140	22	initiate	initiate	VBP
cord-312486-rumqopg0	140	23	downstream	downstream	RB
cord-312486-rumqopg0	140	24	signaling	signal	VBG
cord-312486-rumqopg0	140	25	pathways	pathway	NNS
cord-312486-rumqopg0	140	26	triggering	trigger	VBG
cord-312486-rumqopg0	140	27	secretion	secretion	NN
cord-312486-rumqopg0	140	28	of	of	IN
cord-312486-rumqopg0	140	29	cytokines	cytokine	NNS
cord-312486-rumqopg0	140	30	.	.	.
cord-312486-rumqopg0	141	1	If	if	IN
cord-312486-rumqopg0	141	2	present	present	JJ
cord-312486-rumqopg0	141	3	early	early	RB
cord-312486-rumqopg0	141	4	and	and	CC
cord-312486-rumqopg0	141	5	properly	properly	RB
cord-312486-rumqopg0	141	6	localized	localize	VBN
cord-312486-rumqopg0	141	7	,	,	,
cord-312486-rumqopg0	141	8	IFN	IFN	NNP
cord-312486-rumqopg0	141	9	are	be	VBP
cord-312486-rumqopg0	141	10	considered	consider	VBN
cord-312486-rumqopg0	141	11	the	the	DT
cord-312486-rumqopg0	141	12	most	most	RBS
cord-312486-rumqopg0	141	13	effective	effective	JJ
cord-312486-rumqopg0	141	14	in	in	IN
cord-312486-rumqopg0	141	15	limiting	limit	VBG
cord-312486-rumqopg0	141	16	CoV	cov	NN
cord-312486-rumqopg0	141	17	infections	infection	NNS
cord-312486-rumqopg0	141	18	[	[	-LRB-
cord-312486-rumqopg0	141	19	68	68	CD
cord-312486-rumqopg0	141	20	]	]	-RRB-
cord-312486-rumqopg0	141	21	.	.	.
cord-312486-rumqopg0	142	1	IFN	IFN	NNP
cord-312486-rumqopg0	142	2	induced	induce	VBD
cord-312486-rumqopg0	142	3	proteins	protein	NNS
cord-312486-rumqopg0	142	4	can	can	MD
cord-312486-rumqopg0	142	5	interfere	interfere	VB
cord-312486-rumqopg0	142	6	with	with	IN
cord-312486-rumqopg0	142	7	viral	viral	JJ
cord-312486-rumqopg0	142	8	entry	entry	NN
cord-312486-rumqopg0	142	9	and	and	CC
cord-312486-rumqopg0	142	10	S	s	NN
cord-312486-rumqopg0	142	11	-	-	HYPH
cord-312486-rumqopg0	142	12	protein	protein	NN
cord-312486-rumqopg0	142	13	-	-	HYPH
cord-312486-rumqopg0	142	14	mediated	mediate	VBN
cord-312486-rumqopg0	142	15	membrane	membrane	NN
cord-312486-rumqopg0	142	16	fusion	fusion	NN
cord-312486-rumqopg0	142	17	[	[	-LRB-
cord-312486-rumqopg0	142	18	69	69	CD
cord-312486-rumqopg0	142	19	,	,	,
cord-312486-rumqopg0	142	20	70	70	CD
cord-312486-rumqopg0	142	21	]	]	-RRB-
cord-312486-rumqopg0	142	22	.	.	.
cord-312486-rumqopg0	143	1	However	however	RB
cord-312486-rumqopg0	143	2	,	,	,
cord-312486-rumqopg0	143	3	in	in	IN
cord-312486-rumqopg0	143	4	a	a	DT
cord-312486-rumqopg0	143	5	later	later	JJ
cord-312486-rumqopg0	143	6	phase	phase	NN
cord-312486-rumqopg0	143	7	of	of	IN
cord-312486-rumqopg0	143	8	the	the	DT
cord-312486-rumqopg0	143	9	infection	infection	NN
cord-312486-rumqopg0	143	10	,	,	,
cord-312486-rumqopg0	143	11	IFN	IFN	NNP
cord-312486-rumqopg0	143	12	can	can	MD
cord-312486-rumqopg0	143	13	become	become	VB
cord-312486-rumqopg0	143	14	pathologic	pathologic	JJ
cord-312486-rumqopg0	143	15	(	(	-LRB-
cord-312486-rumqopg0	143	16	e.g.	e.g.	IN
cord-312486-rumqopg0	143	17	upregulation	upregulation	NN
cord-312486-rumqopg0	143	18	of	of	IN
cord-312486-rumqopg0	143	19	ACE2	ACE2	NNP
cord-312486-rumqopg0	143	20	in	in	IN
cord-312486-rumqopg0	143	21	airway	airway	NN
cord-312486-rumqopg0	143	22	epithelium	epithelium	NN
cord-312486-rumqopg0	143	23	[	[	-LRB-
cord-312486-rumqopg0	143	24	45	45	CD
cord-312486-rumqopg0	143	25	]	]	-RRB-
cord-312486-rumqopg0	143	26	and	and	CC
cord-312486-rumqopg0	143	27	orchestration	orchestration	NN
cord-312486-rumqopg0	143	28	of	of	IN
cord-312486-rumqopg0	143	29	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	143	30	response	response	NN
cord-312486-rumqopg0	143	31	contributing	contribute	VBG
cord-312486-rumqopg0	143	32	to	to	IN
cord-312486-rumqopg0	143	33	immuno	immuno	JJ
cord-312486-rumqopg0	143	34	-	-	JJ
cord-312486-rumqopg0	143	35	pathogenesis	pathogenesis	NN
cord-312486-rumqopg0	143	36	[	[	-LRB-
cord-312486-rumqopg0	143	37	127	127	CD
cord-312486-rumqopg0	143	38	]	]	-RRB-
cord-312486-rumqopg0	143	39	)	)	-RRB-
cord-312486-rumqopg0	143	40	.	.	.
cord-312486-rumqopg0	144	1	SARS	SARS	NNP
cord-312486-rumqopg0	144	2	-	-	HYPH
cord-312486-rumqopg0	144	3	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	144	4	,	,	,
cord-312486-rumqopg0	144	5	similar	similar	JJ
cord-312486-rumqopg0	144	6	to	to	IN
cord-312486-rumqopg0	144	7	other	other	JJ
cord-312486-rumqopg0	144	8	CoV	cov	NN
cord-312486-rumqopg0	144	9	,	,	,
cord-312486-rumqopg0	144	10	have	have	VBP
cord-312486-rumqopg0	144	11	developed	develop	VBN
cord-312486-rumqopg0	144	12	multifaceted	multifaceted	JJ
cord-312486-rumqopg0	144	13	mechanisms	mechanism	NNS
cord-312486-rumqopg0	144	14	to	to	TO
cord-312486-rumqopg0	144	15	inhibit	inhibit	VB
cord-312486-rumqopg0	144	16	IFN	IFN	NNP
cord-312486-rumqopg0	144	17	induction	induction	NN
cord-312486-rumqopg0	144	18	and	and	CC
cord-312486-rumqopg0	144	19	signaling	signal	VBG
cord-312486-rumqopg0	144	20	[	[	-LRB-
cord-312486-rumqopg0	144	21	71	71	CD
cord-312486-rumqopg0	144	22	]	]	-RRB-
cord-312486-rumqopg0	144	23	.	.	.
cord-312486-rumqopg0	145	1	This	this	DT
cord-312486-rumqopg0	145	2	is	be	VBZ
cord-312486-rumqopg0	145	3	evident	evident	JJ
cord-312486-rumqopg0	145	4	by	by	IN
cord-312486-rumqopg0	145	5	an	an	DT
cord-312486-rumqopg0	145	6	early	early	JJ
cord-312486-rumqopg0	145	7	impaired	impair	VBN
cord-312486-rumqopg0	145	8	IFN	IFN	NNP
cord-312486-rumqopg0	145	9	signature	signature	NN
cord-312486-rumqopg0	145	10	in	in	IN
cord-312486-rumqopg0	145	11	severe	severe	JJ
cord-312486-rumqopg0	145	12	COVID-19	covid-19	JJ
cord-312486-rumqopg0	145	13	patients	patient	NNS
cord-312486-rumqopg0	145	14	[	[	-LRB-
cord-312486-rumqopg0	145	15	72	72	CD
cord-312486-rumqopg0	145	16	,	,	,
cord-312486-rumqopg0	145	17	73	73	CD
cord-312486-rumqopg0	145	18	]	]	-RRB-
cord-312486-rumqopg0	145	19	,	,	,
cord-312486-rumqopg0	145	20	while	while	IN
cord-312486-rumqopg0	145	21	actively	actively	RB
cord-312486-rumqopg0	145	22	promoting	promote	VBG
cord-312486-rumqopg0	145	23	other	other	JJ
cord-312486-rumqopg0	145	24	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	145	25	pathways	pathway	NNS
cord-312486-rumqopg0	145	26	contributing	contribute	VBG
cord-312486-rumqopg0	145	27	to	to	IN
cord-312486-rumqopg0	145	28	pathology	pathology	NN
cord-312486-rumqopg0	145	29	(	(	-LRB-
cord-312486-rumqopg0	145	30	e.g.	e.g.	IN
cord-312486-rumqopg0	145	31	secretion	secretion	NN
cord-312486-rumqopg0	145	32	of	of	IN
cord-312486-rumqopg0	145	33	pro	pro	JJ
cord-312486-rumqopg0	145	34	-	-	JJ
cord-312486-rumqopg0	145	35	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	145	36	cytokines	cytokine	NNS
cord-312486-rumqopg0	145	37	interleukin	interleukin	NN
cord-312486-rumqopg0	145	38	(	(	-LRB-
cord-312486-rumqopg0	145	39	IL	IL	NNP
cord-312486-rumqopg0	145	40	)	)	-RRB-
cord-312486-rumqopg0	145	41	1β	1β	CD
cord-312486-rumqopg0	145	42	(	(	-LRB-
cord-312486-rumqopg0	145	43	IL-1β	il-1β	NN
cord-312486-rumqopg0	145	44	)	)	-RRB-
cord-312486-rumqopg0	145	45	and	and	CC
cord-312486-rumqopg0	145	46	IL-18	IL-18	NNP
cord-312486-rumqopg0	145	47	[	[	-LRB-
cord-312486-rumqopg0	145	48	74	74	CD
cord-312486-rumqopg0	145	49	]	]	-RRB-
cord-312486-rumqopg0	145	50	)	)	-RRB-
cord-312486-rumqopg0	145	51	.	.	.
cord-312486-rumqopg0	146	1	SARS	SARS	NNP
cord-312486-rumqopg0	146	2	-	-	HYPH
cord-312486-rumqopg0	146	3	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	146	4	is	be	VBZ
cord-312486-rumqopg0	146	5	particularly	particularly	RB
cord-312486-rumqopg0	146	6	effective	effective	JJ
cord-312486-rumqopg0	146	7	in	in	IN
cord-312486-rumqopg0	146	8	inducing	induce	VBG
cord-312486-rumqopg0	146	9	IL-6	IL-6	NNP
cord-312486-rumqopg0	146	10	and	and	CC
cord-312486-rumqopg0	146	11	IL-8	IL-8	NNP
cord-312486-rumqopg0	146	12	,	,	,
cord-312486-rumqopg0	146	13	by	by	IN
cord-312486-rumqopg0	146	14	inhibiting	inhibit	VBG
cord-312486-rumqopg0	146	15	an	an	DT
cord-312486-rumqopg0	146	16	endogenous	endogenous	JJ
cord-312486-rumqopg0	146	17	NF	nf	NN
cord-312486-rumqopg0	146	18	-	-	HYPH
cord-312486-rumqopg0	146	19	kB	kB	NNP
cord-312486-rumqopg0	146	20	repressor	repressor	NN
cord-312486-rumqopg0	146	21	,	,	,
cord-312486-rumqopg0	146	22	NKRF	NKRF	NNP
cord-312486-rumqopg0	146	23	[	[	-LRB-
cord-312486-rumqopg0	146	24	75	75	CD
cord-312486-rumqopg0	146	25	]	]	-RRB-
cord-312486-rumqopg0	147	1	but	but	CC
cord-312486-rumqopg0	147	2	probably	probably	RB
cord-312486-rumqopg0	147	3	by	by	IN
cord-312486-rumqopg0	147	4	other	other	JJ
cord-312486-rumqopg0	147	5	mechanisms	mechanism	NNS
cord-312486-rumqopg0	147	6	as	as	RB
cord-312486-rumqopg0	147	7	well	well	RB
cord-312486-rumqopg0	147	8	.	.	.
cord-312486-rumqopg0	148	1	While	while	IN
cord-312486-rumqopg0	148	2	the	the	DT
cord-312486-rumqopg0	148	3	human	human	JJ
cord-312486-rumqopg0	148	4	innate	innate	JJ
cord-312486-rumqopg0	148	5	immune	immune	JJ
cord-312486-rumqopg0	148	6	system	system	NN
cord-312486-rumqopg0	148	7	resources	resource	NNS
cord-312486-rumqopg0	148	8	remained	remain	VBD
cord-312486-rumqopg0	148	9	unchanged	unchanged	JJ
cord-312486-rumqopg0	148	10	,	,	,
cord-312486-rumqopg0	148	11	CoV	CoV	NNP
cord-312486-rumqopg0	148	12	employs	employ	VBZ
cord-312486-rumqopg0	148	13	multiple	multiple	JJ
cord-312486-rumqopg0	148	14	innate	innate	JJ
cord-312486-rumqopg0	148	15	immunity	immunity	NN
cord-312486-rumqopg0	148	16	evasion	evasion	NN
cord-312486-rumqopg0	148	17	mechanisms	mechanism	NNS
cord-312486-rumqopg0	148	18	as	as	IN
cord-312486-rumqopg0	148	19	reviewed	review	VBN
cord-312486-rumqopg0	148	20	recently	recently	RB
cord-312486-rumqopg0	148	21	[	[	-LRB-
cord-312486-rumqopg0	148	22	27	27	CD
cord-312486-rumqopg0	148	23	,	,	,
cord-312486-rumqopg0	148	24	76	76	CD
cord-312486-rumqopg0	148	25	]	]	-RRB-
cord-312486-rumqopg0	148	26	.	.	.
cord-312486-rumqopg0	149	1	The	the	DT
cord-312486-rumqopg0	149	2	earlier	early	JJR
cord-312486-rumqopg0	149	3	CoV	cov	NN
cord-312486-rumqopg0	149	4	infections	infection	NNS
cord-312486-rumqopg0	149	5	can	can	MD
cord-312486-rumqopg0	149	6	provide	provide	VB
cord-312486-rumqopg0	149	7	an	an	DT
cord-312486-rumqopg0	149	8	important	important	JJ
cord-312486-rumqopg0	149	9	road	road	NN
cord-312486-rumqopg0	149	10	map	map	NN
cord-312486-rumqopg0	149	11	to	to	TO
cord-312486-rumqopg0	149	12	understand	understand	VB
cord-312486-rumqopg0	149	13	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	149	14	pathogenesis	pathogenesis	NN
cord-312486-rumqopg0	149	15	.	.	.
cord-312486-rumqopg0	150	1	Thus	thus	RB
cord-312486-rumqopg0	150	2	,	,	,
cord-312486-rumqopg0	150	3	a	a	DT
cord-312486-rumqopg0	150	4	clear	clear	JJ
cord-312486-rumqopg0	150	5	indication	indication	NN
cord-312486-rumqopg0	150	6	that	that	IN
cord-312486-rumqopg0	150	7	immunopathogenesis	immunopathogenesis	NN
cord-312486-rumqopg0	150	8	contributes	contribute	VBZ
cord-312486-rumqopg0	150	9	to	to	IN
cord-312486-rumqopg0	150	10	SARS	SARS	NNP
cord-312486-rumqopg0	150	11	was	be	VBD
cord-312486-rumqopg0	150	12	the	the	DT
cord-312486-rumqopg0	150	13	observation	observation	NN
cord-312486-rumqopg0	150	14	that	that	IN
cord-312486-rumqopg0	150	15	SARS	SARS	NNP
cord-312486-rumqopg0	150	16	-	-	HYPH
cord-312486-rumqopg0	150	17	CoV-1	CoV-1	NNP
cord-312486-rumqopg0	150	18	viral	viral	JJ
cord-312486-rumqopg0	150	19	loads	load	NNS
cord-312486-rumqopg0	150	20	were	be	VBD
cord-312486-rumqopg0	150	21	found	find	VBN
cord-312486-rumqopg0	150	22	to	to	TO
cord-312486-rumqopg0	150	23	be	be	VB
cord-312486-rumqopg0	150	24	decreasing	decrease	VBG
cord-312486-rumqopg0	150	25	while	while	IN
cord-312486-rumqopg0	150	26	disease	disease	NN
cord-312486-rumqopg0	150	27	severity	severity	NN
cord-312486-rumqopg0	150	28	increased	increase	VBD
cord-312486-rumqopg0	150	29	[	[	-LRB-
cord-312486-rumqopg0	150	30	77	77	CD
cord-312486-rumqopg0	150	31	,	,	,
cord-312486-rumqopg0	150	32	78	78	CD
cord-312486-rumqopg0	150	33	]	]	-RRB-
cord-312486-rumqopg0	150	34	.	.	.
cord-312486-rumqopg0	151	1	Longitudinal	longitudinal	JJ
cord-312486-rumqopg0	151	2	in	in	IN
cord-312486-rumqopg0	151	3	vivo	vivo	NN
cord-312486-rumqopg0	151	4	experiments	experiment	NNS
cord-312486-rumqopg0	151	5	in	in	IN
cord-312486-rumqopg0	151	6	which	which	WDT
cord-312486-rumqopg0	151	7	ferrets	ferret	NNS
cord-312486-rumqopg0	151	8	were	be	VBD
cord-312486-rumqopg0	151	9	infected	infect	VBN
cord-312486-rumqopg0	151	10	with	with	IN
cord-312486-rumqopg0	151	11	SARS	SARS	NNP
cord-312486-rumqopg0	151	12	-	-	HYPH
cord-312486-rumqopg0	151	13	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	151	14	intranasally	intranasally	RB
cord-312486-rumqopg0	151	15	showed	show	VBD
cord-312486-rumqopg0	151	16	a	a	DT
cord-312486-rumqopg0	151	17	robust	robust	JJ
cord-312486-rumqopg0	151	18	production	production	NN
cord-312486-rumqopg0	151	19	of	of	IN
cord-312486-rumqopg0	151	20	cytokines	cytokine	NNS
cord-312486-rumqopg0	151	21	that	that	WDT
cord-312486-rumqopg0	151	22	continued	continue	VBD
cord-312486-rumqopg0	151	23	beyond	beyond	IN
cord-312486-rumqopg0	151	24	clearance	clearance	NN
cord-312486-rumqopg0	151	25	of	of	IN
cord-312486-rumqopg0	151	26	the	the	DT
cord-312486-rumqopg0	151	27	virus	virus	NN
cord-312486-rumqopg0	151	28	.	.	.
cord-312486-rumqopg0	152	1	By	by	IN
cord-312486-rumqopg0	152	2	day	day	NN
cord-312486-rumqopg0	152	3	seven	seven	CD
cord-312486-rumqopg0	152	4	,	,	,
cord-312486-rumqopg0	152	5	despite	despite	IN
cord-312486-rumqopg0	152	6	waning	wane	VBG
cord-312486-rumqopg0	152	7	viral	viral	JJ
cord-312486-rumqopg0	152	8	burden	burden	NN
cord-312486-rumqopg0	152	9	,	,	,
cord-312486-rumqopg0	152	10	the	the	DT
cord-312486-rumqopg0	152	11	cytokine	cytokine	NN
cord-312486-rumqopg0	152	12	response	response	NN
cord-312486-rumqopg0	152	13	continued	continue	VBD
cord-312486-rumqopg0	152	14	to	to	TO
cord-312486-rumqopg0	152	15	expend	expend	VB
cord-312486-rumqopg0	152	16	.	.	.
cord-312486-rumqopg0	153	1	Remarkably	remarkably	RB
cord-312486-rumqopg0	153	2	,	,	,
cord-312486-rumqopg0	153	3	by	by	IN
cord-312486-rumqopg0	153	4	day	day	NN
cord-312486-rumqopg0	153	5	fourteen	fourteen	CD
cord-312486-rumqopg0	153	6	,	,	,
cord-312486-rumqopg0	153	7	while	while	IN
cord-312486-rumqopg0	153	8	the	the	DT
cord-312486-rumqopg0	153	9	virus	virus	NN
cord-312486-rumqopg0	153	10	was	be	VBD
cord-312486-rumqopg0	153	11	fully	fully	RB
cord-312486-rumqopg0	153	12	cleared	clear	VBN
cord-312486-rumqopg0	153	13	,	,	,
cord-312486-rumqopg0	153	14	some	some	DT
cord-312486-rumqopg0	153	15	cytokines	cytokine	NNS
cord-312486-rumqopg0	153	16	and	and	CC
cord-312486-rumqopg0	153	17	specifically	specifically	RB
cord-312486-rumqopg0	153	18	IL-6	IL-6	NNP
cord-312486-rumqopg0	153	19	remained	remain	VBD
cord-312486-rumqopg0	153	20	elevated	elevated	JJ
cord-312486-rumqopg0	153	21	[	[	-LRB-
cord-312486-rumqopg0	153	22	73	73	CD
cord-312486-rumqopg0	153	23	]	]	-RRB-
cord-312486-rumqopg0	153	24	.	.	.
cord-312486-rumqopg0	154	1	In	in	IN
cord-312486-rumqopg0	154	2	fact	fact	NN
cord-312486-rumqopg0	154	3	,	,	,
cord-312486-rumqopg0	154	4	IL-6	IL-6	NNP
cord-312486-rumqopg0	154	5	emerges	emerge	VBZ
cord-312486-rumqopg0	154	6	as	as	IN
cord-312486-rumqopg0	154	7	the	the	DT
cord-312486-rumqopg0	154	8	dominant	dominant	JJ
cord-312486-rumqopg0	154	9	cytokine	cytokine	NN
cord-312486-rumqopg0	154	10	driving	drive	VBG
cord-312486-rumqopg0	154	11	the	the	DT
cord-312486-rumqopg0	154	12	immunopathogenesis	immunopathogenesis	NN
cord-312486-rumqopg0	154	13	.	.	.
cord-312486-rumqopg0	155	1	Given	give	VBN
cord-312486-rumqopg0	155	2	that	that	DT
cord-312486-rumqopg0	155	3	old	old	JJ
cord-312486-rumqopg0	155	4	age	age	NN
cord-312486-rumqopg0	155	5	appears	appear	VBZ
cord-312486-rumqopg0	155	6	to	to	TO
cord-312486-rumqopg0	155	7	be	be	VB
cord-312486-rumqopg0	155	8	an	an	DT
cord-312486-rumqopg0	155	9	independent	independent	JJ
cord-312486-rumqopg0	155	10	risk	risk	NN
cord-312486-rumqopg0	155	11	factor	factor	NN
cord-312486-rumqopg0	155	12	for	for	IN
cord-312486-rumqopg0	155	13	developing	develop	VBG
cord-312486-rumqopg0	155	14	severe	severe	JJ
cord-312486-rumqopg0	155	15	COVID-19	covid-19	DT
cord-312486-rumqopg0	155	16	[	[	-LRB-
cord-312486-rumqopg0	155	17	79	79	CD
cord-312486-rumqopg0	155	18	]	]	-RRB-
cord-312486-rumqopg0	155	19	,	,	,
cord-312486-rumqopg0	155	20	it	-PRON-	PRP
cord-312486-rumqopg0	155	21	is	be	VBZ
cord-312486-rumqopg0	155	22	noteworthy	noteworthy	JJ
cord-312486-rumqopg0	155	23	that	that	IN
cord-312486-rumqopg0	155	24	in	in	IN
cord-312486-rumqopg0	155	25	a	a	DT
cord-312486-rumqopg0	155	26	groundbreaking	groundbreaking	JJ
cord-312486-rumqopg0	155	27	study	study	NN
cord-312486-rumqopg0	155	28	Ter	Ter	NNP
cord-312486-rumqopg0	155	29	Horst	Horst	NNP
cord-312486-rumqopg0	155	30	et	et	NNP
cord-312486-rumqopg0	155	31	al	al	NNP
cord-312486-rumqopg0	155	32	.	.	NNP
cord-312486-rumqopg0	155	33	,	,	,
cord-312486-rumqopg0	155	34	have	have	VBP
cord-312486-rumqopg0	155	35	shown	show	VBN
cord-312486-rumqopg0	155	36	a	a	DT
cord-312486-rumqopg0	155	37	clear	clear	JJ
cord-312486-rumqopg0	155	38	and	and	CC
cord-312486-rumqopg0	155	39	consistent	consistent	JJ
cord-312486-rumqopg0	155	40	increase	increase	NN
cord-312486-rumqopg0	155	41	in	in	IN
cord-312486-rumqopg0	155	42	IL-6	IL-6	NNP
cord-312486-rumqopg0	155	43	and	and	CC
cord-312486-rumqopg0	155	44	IL-1RA	IL-1RA	NNP
cord-312486-rumqopg0	155	45	production	production	NN
cord-312486-rumqopg0	155	46	in	in	IN
cord-312486-rumqopg0	155	47	old	old	JJ
cord-312486-rumqopg0	155	48	age	age	NN
cord-312486-rumqopg0	155	49	[	[	-LRB-
cord-312486-rumqopg0	155	50	80	80	CD
cord-312486-rumqopg0	155	51	]	]	-RRB-
cord-312486-rumqopg0	155	52	.	.	.
cord-312486-rumqopg0	156	1	Evidence	evidence	NN
cord-312486-rumqopg0	156	2	is	be	VBZ
cord-312486-rumqopg0	156	3	accumulating	accumulate	VBG
cord-312486-rumqopg0	156	4	in	in	IN
cord-312486-rumqopg0	156	5	COVID-19	covid-19	JJ
cord-312486-rumqopg0	156	6	patients	patient	NNS
cord-312486-rumqopg0	156	7	pointing	point	VBG
cord-312486-rumqopg0	156	8	to	to	IN
cord-312486-rumqopg0	156	9	dysregulated	dysregulate	VBN
cord-312486-rumqopg0	156	10	monocyte	monocyte	NNP
cord-312486-rumqopg0	156	11	driven	drive	VBN
cord-312486-rumqopg0	156	12	dendritic	dendritic	JJ
cord-312486-rumqopg0	156	13	cells	cell	NNS
cord-312486-rumqopg0	156	14	and	and	CC
cord-312486-rumqopg0	156	15	macrophage	macrophage	NN
cord-312486-rumqopg0	156	16	responses	response	NNS
cord-312486-rumqopg0	156	17	,	,	,
cord-312486-rumqopg0	156	18	which	which	WDT
cord-312486-rumqopg0	156	19	then	then	RB
cord-312486-rumqopg0	156	20	drive	drive	VBP
cord-312486-rumqopg0	156	21	the	the	DT
cord-312486-rumqopg0	156	22	characteristic	characteristic	JJ
cord-312486-rumqopg0	156	23	acute	acute	JJ
cord-312486-rumqopg0	156	24	respiratory	respiratory	JJ
cord-312486-rumqopg0	156	25	distress	distress	NN
cord-312486-rumqopg0	156	26	syndrome	syndrome	NN
cord-312486-rumqopg0	156	27	(	(	-LRB-
cord-312486-rumqopg0	156	28	ARDS	ARDS	NNP
cord-312486-rumqopg0	156	29	)	)	-RRB-
cord-312486-rumqopg0	156	30	and	and	CC
cord-312486-rumqopg0	156	31	cytokine	cytokine	NN
cord-312486-rumqopg0	156	32	release	release	NN
cord-312486-rumqopg0	156	33	syndrome	syndrome	NN
cord-312486-rumqopg0	156	34	(	(	-LRB-
cord-312486-rumqopg0	156	35	CRS	CRS	NNP
cord-312486-rumqopg0	156	36	)	)	-RRB-
cord-312486-rumqopg0	157	1	[	[	-LRB-
cord-312486-rumqopg0	157	2	81	81	CD
cord-312486-rumqopg0	157	3	]	]	-RRB-
cord-312486-rumqopg0	157	4	.	.	.
cord-312486-rumqopg0	158	1	CD56	cd56	NN
cord-312486-rumqopg0	158	2	dim	dim	NN
cord-312486-rumqopg0	158	3	NK	NK	NNP
cord-312486-rumqopg0	158	4	cells	cell	NNS
cord-312486-rumqopg0	158	5	,	,	,
cord-312486-rumqopg0	158	6	generally	generally	RB
cord-312486-rumqopg0	158	7	thought	think	VBN
cord-312486-rumqopg0	158	8	to	to	TO
cord-312486-rumqopg0	158	9	contribute	contribute	VB
cord-312486-rumqopg0	158	10	to	to	IN
cord-312486-rumqopg0	158	11	antiviral	antiviral	JJ
cord-312486-rumqopg0	158	12	host	host	NN
cord-312486-rumqopg0	158	13	defense	defense	NN
cord-312486-rumqopg0	158	14	through	through	IN
cord-312486-rumqopg0	158	15	cellmediated	cellmediate	VBN
cord-312486-rumqopg0	158	16	cytotoxicity	cytotoxicity	NN
cord-312486-rumqopg0	158	17	,	,	,
cord-312486-rumqopg0	158	18	were	be	VBD
cord-312486-rumqopg0	158	19	depleted	deplete	VBN
cord-312486-rumqopg0	158	20	primarily	primarily	RB
cord-312486-rumqopg0	158	21	in	in	IN
cord-312486-rumqopg0	158	22	severe	severe	JJ
cord-312486-rumqopg0	158	23	cases	case	NNS
cord-312486-rumqopg0	158	24	.	.	.
cord-312486-rumqopg0	159	1	Whereas	whereas	IN
cord-312486-rumqopg0	159	2	CD56	CD56	NNP
cord-312486-rumqopg0	159	3	bright	bright	JJ
cord-312486-rumqopg0	159	4	NK	NK	NNP
cord-312486-rumqopg0	159	5	cells	cell	NNS
cord-312486-rumqopg0	159	6	,	,	,
cord-312486-rumqopg0	159	7	which	which	WDT
cord-312486-rumqopg0	159	8	are	be	VBP
cord-312486-rumqopg0	159	9	considered	consider	VBN
cord-312486-rumqopg0	159	10	producers	producer	NNS
cord-312486-rumqopg0	159	11	of	of	IN
cord-312486-rumqopg0	159	12	IFN	IFN	NNP
cord-312486-rumqopg0	159	13	-	-	HYPH
cord-312486-rumqopg0	159	14	γ	γ	NNP
cord-312486-rumqopg0	159	15	and	and	CC
cord-312486-rumqopg0	159	16	TNF	TNF	NNP
cord-312486-rumqopg0	159	17	-	-	HYPH
cord-312486-rumqopg0	159	18	α	α	NNP
cord-312486-rumqopg0	159	19	,	,	,
cord-312486-rumqopg0	159	20	were	be	VBD
cord-312486-rumqopg0	159	21	significantly	significantly	RB
cord-312486-rumqopg0	159	22	depleted	deplete	VBN
cord-312486-rumqopg0	159	23	in	in	IN
cord-312486-rumqopg0	159	24	all	all	DT
cord-312486-rumqopg0	159	25	COVID-19	covid-19	JJ
cord-312486-rumqopg0	159	26	samples	sample	NNS
cord-312486-rumqopg0	159	27	tested	test	VBD
cord-312486-rumqopg0	159	28	[	[	-LRB-
cord-312486-rumqopg0	159	29	82	82	CD
cord-312486-rumqopg0	159	30	]	]	-RRB-
cord-312486-rumqopg0	159	31	.	.	.
cord-312486-rumqopg0	160	1	Evidence	evidence	NN
cord-312486-rumqopg0	160	2	supports	support	VBZ
cord-312486-rumqopg0	160	3	recruitment	recruitment	NN
cord-312486-rumqopg0	160	4	of	of	IN
cord-312486-rumqopg0	160	5	NK	NK	NNP
cord-312486-rumqopg0	160	6	cells	cell	NNS
cord-312486-rumqopg0	160	7	from	from	IN
cord-312486-rumqopg0	160	8	the	the	DT
cord-312486-rumqopg0	160	9	periphery	periphery	NN
cord-312486-rumqopg0	160	10	to	to	IN
cord-312486-rumqopg0	160	11	the	the	DT
cord-312486-rumqopg0	160	12	lung	lung	NN
cord-312486-rumqopg0	160	13	.	.	.
cord-312486-rumqopg0	161	1	Activation	activation	NN
cord-312486-rumqopg0	161	2	of	of	IN
cord-312486-rumqopg0	161	3	these	these	DT
cord-312486-rumqopg0	161	4	NK	NK	NNP
cord-312486-rumqopg0	161	5	cells	cell	NNS
cord-312486-rumqopg0	161	6	in	in	IN
cord-312486-rumqopg0	161	7	the	the	DT
cord-312486-rumqopg0	161	8	target	target	NN
cord-312486-rumqopg0	161	9	tissue	tissue	NN
cord-312486-rumqopg0	161	10	in	in	IN
cord-312486-rumqopg0	161	11	an	an	DT
cord-312486-rumqopg0	161	12	environment	environment	NN
cord-312486-rumqopg0	161	13	enriched	enrich	VBN
cord-312486-rumqopg0	161	14	for	for	IN
cord-312486-rumqopg0	161	15	IL-6	IL-6	NNP
cord-312486-rumqopg0	161	16	(	(	-LRB-
cord-312486-rumqopg0	161	17	and	and	CC
cord-312486-rumqopg0	161	18	other	other	JJ
cord-312486-rumqopg0	161	19	cytokines	cytokine	NNS
cord-312486-rumqopg0	161	20	)	)	-RRB-
cord-312486-rumqopg0	161	21	probably	probably	RB
cord-312486-rumqopg0	161	22	contributes	contribute	VBZ
cord-312486-rumqopg0	161	23	to	to	TO
cord-312486-rumqopg0	161	24	pathogenesis	pathogenesis	VB
cord-312486-rumqopg0	161	25	[	[	-LRB-
cord-312486-rumqopg0	161	26	76	76	CD
cord-312486-rumqopg0	161	27	,	,	,
cord-312486-rumqopg0	161	28	83	83	CD
cord-312486-rumqopg0	161	29	]	]	-RRB-
cord-312486-rumqopg0	161	30	,	,	,
cord-312486-rumqopg0	161	31	as	as	IN
cord-312486-rumqopg0	161	32	opposed	oppose	VBN
cord-312486-rumqopg0	161	33	to	to	IN
cord-312486-rumqopg0	161	34	resolving	resolve	VBG
cord-312486-rumqopg0	161	35	the	the	DT
cord-312486-rumqopg0	161	36	infection	infection	NN
cord-312486-rumqopg0	161	37	.	.	.
cord-312486-rumqopg0	162	1	Severe	severe	JJ
cord-312486-rumqopg0	162	2	cases	case	NNS
cord-312486-rumqopg0	162	3	of	of	IN
cord-312486-rumqopg0	162	4	COVID-19	COVID-19	,
cord-312486-rumqopg0	162	5	have	have	VBP
cord-312486-rumqopg0	162	6	significant	significant	JJ
cord-312486-rumqopg0	162	7	increase	increase	NN
cord-312486-rumqopg0	162	8	in	in	IN
cord-312486-rumqopg0	162	9	neutrophil	neutrophil	NN
cord-312486-rumqopg0	162	10	levels	level	NNS
cord-312486-rumqopg0	162	11	in	in	IN
cord-312486-rumqopg0	162	12	circulation	circulation	NN
cord-312486-rumqopg0	162	13	[	[	-LRB-
cord-312486-rumqopg0	162	14	84	84	CD
cord-312486-rumqopg0	162	15	,	,	,
cord-312486-rumqopg0	162	16	85	85	CD
cord-312486-rumqopg0	162	17	]	]	-RRB-
cord-312486-rumqopg0	162	18	and	and	CC
cord-312486-rumqopg0	162	19	in	in	IN
cord-312486-rumqopg0	162	20	bronchoalveolar	bronchoalveolar	NNP
cord-312486-rumqopg0	162	21	lavage	lavage	NN
cord-312486-rumqopg0	162	22	fluid	fluid	NN
cord-312486-rumqopg0	162	23	(	(	-LRB-
cord-312486-rumqopg0	162	24	BALF	BALF	NNP
cord-312486-rumqopg0	162	25	)	)	-RRB-
cord-312486-rumqopg0	162	26	[	[	-LRB-
cord-312486-rumqopg0	162	27	86	86	CD
cord-312486-rumqopg0	162	28	]	]	-RRB-
cord-312486-rumqopg0	162	29	.	.	.
cord-312486-rumqopg0	163	1	Together	together	RB
cord-312486-rumqopg0	163	2	with	with	IN
cord-312486-rumqopg0	163	3	the	the	DT
cord-312486-rumqopg0	163	4	upregulation	upregulation	NN
cord-312486-rumqopg0	163	5	of	of	IN
cord-312486-rumqopg0	163	6	chemokines	chemokine	NNS
cord-312486-rumqopg0	163	7	,	,	,
cord-312486-rumqopg0	163	8	particularly	particularly	RB
cord-312486-rumqopg0	163	9	those	those	DT
cord-312486-rumqopg0	163	10	that	that	WDT
cord-312486-rumqopg0	163	11	act	act	NN
cord-312486-rumqopg0	163	12	as	as	IN
cord-312486-rumqopg0	163	13	chemoattractants	chemoattractant	NNS
cord-312486-rumqopg0	163	14	for	for	IN
cord-312486-rumqopg0	163	15	neutrophils	neutrophil	NNS
cord-312486-rumqopg0	163	16	and	and	CC
cord-312486-rumqopg0	163	17	monocytes	monocyte	VBZ
cord-312486-rumqopg0	163	18	J	J	NNP
cord-312486-rumqopg0	163	19	o	o	NN
cord-312486-rumqopg0	163	20	u	u	NN
cord-312486-rumqopg0	163	21	r	r	NN
cord-312486-rumqopg0	163	22	n	n	NN
cord-312486-rumqopg0	163	23	a	a	DT
cord-312486-rumqopg0	163	24	l	l	NN
cord-312486-rumqopg0	163	25	P	p	NN
cord-312486-rumqopg0	163	26	r	r	NN
cord-312486-rumqopg0	163	27	e	e	NN
cord-312486-rumqopg0	163	28	-p	-p	NN
cord-312486-rumqopg0	164	1	r	r	LS
cord-312486-rumqopg0	165	1	o	o	UH
cord-312486-rumqopg0	166	1	o	o	UH
cord-312486-rumqopg0	166	2	f	f	NNP
cord-312486-rumqopg0	166	3	[	[	-LRB-
cord-312486-rumqopg0	166	4	73	73	CD
cord-312486-rumqopg0	166	5	,	,	,
cord-312486-rumqopg0	166	6	[	[	-LRB-
cord-312486-rumqopg0	166	7	86	86	CD
cord-312486-rumqopg0	166	8	]	]	-RRB-
cord-312486-rumqopg0	166	9	[	[	-LRB-
cord-312486-rumqopg0	166	10	87	87	CD
cord-312486-rumqopg0	166	11	]	]	-RRB-
cord-312486-rumqopg0	167	1	[	[	-LRB-
cord-312486-rumqopg0	167	2	88	88	CD
cord-312486-rumqopg0	167	3	]	]	-RRB-
cord-312486-rumqopg0	167	4	,	,	,
cord-312486-rumqopg0	167	5	these	these	DT
cord-312486-rumqopg0	167	6	observations	observation	NNS
cord-312486-rumqopg0	167	7	support	support	VBP
cord-312486-rumqopg0	167	8	the	the	DT
cord-312486-rumqopg0	167	9	influx	influx	NN
cord-312486-rumqopg0	167	10	of	of	IN
cord-312486-rumqopg0	167	11	these	these	DT
cord-312486-rumqopg0	167	12	cell	cell	NN
cord-312486-rumqopg0	167	13	types	type	NNS
cord-312486-rumqopg0	167	14	into	into	IN
cord-312486-rumqopg0	167	15	the	the	DT
cord-312486-rumqopg0	167	16	bronchi	bronchi	NN
cord-312486-rumqopg0	167	17	.	.	.
cord-312486-rumqopg0	168	1	These	these	DT
cord-312486-rumqopg0	168	2	neutrophils	neutrophil	NNS
cord-312486-rumqopg0	168	3	and	and	CC
cord-312486-rumqopg0	168	4	monocytes	monocyte	NNS
cord-312486-rumqopg0	168	5	probably	probably	RB
cord-312486-rumqopg0	168	6	disrupt	disrupt	VBP
cord-312486-rumqopg0	168	7	the	the	DT
cord-312486-rumqopg0	168	8	air	air	NN
cord-312486-rumqopg0	168	9	-	-	HYPH
cord-312486-rumqopg0	168	10	blood	blood	NN
cord-312486-rumqopg0	168	11	barrier	barrier	NN
cord-312486-rumqopg0	168	12	by	by	IN
cord-312486-rumqopg0	168	13	causing	cause	VBG
cord-312486-rumqopg0	168	14	collateral	collateral	JJ
cord-312486-rumqopg0	168	15	damage	damage	NN
cord-312486-rumqopg0	168	16	to	to	IN
cord-312486-rumqopg0	168	17	airway	airway	JJ
cord-312486-rumqopg0	168	18	epithelial	epithelial	JJ
cord-312486-rumqopg0	168	19	cells	cell	NNS
cord-312486-rumqopg0	168	20	and	and	CC
cord-312486-rumqopg0	168	21	vascular	vascular	JJ
cord-312486-rumqopg0	168	22	endothelial	endothelial	JJ
cord-312486-rumqopg0	168	23	cells	cell	NNS
cord-312486-rumqopg0	168	24	while	while	IN
cord-312486-rumqopg0	168	25	increasing	increase	VBG
cord-312486-rumqopg0	168	26	cytokine	cytokine	NN
cord-312486-rumqopg0	168	27	production	production	NN
cord-312486-rumqopg0	168	28	.	.	.
cord-312486-rumqopg0	169	1	The	the	DT
cord-312486-rumqopg0	169	2	damage	damage	NN
cord-312486-rumqopg0	169	3	to	to	IN
cord-312486-rumqopg0	169	4	vascular	vascular	JJ
cord-312486-rumqopg0	169	5	endothelial	endothelial	JJ
cord-312486-rumqopg0	169	6	cells	cell	NNS
cord-312486-rumqopg0	169	7	certainly	certainly	RB
cord-312486-rumqopg0	169	8	contributes	contribute	VBZ
cord-312486-rumqopg0	169	9	to	to	IN
cord-312486-rumqopg0	169	10	microthrombosis	microthrombosis	NN
cord-312486-rumqopg0	169	11	.	.	.
cord-312486-rumqopg0	170	1	Though	though	IN
cord-312486-rumqopg0	170	2	seemingly	seemingly	RB
cord-312486-rumqopg0	170	3	contradictory	contradictory	JJ
cord-312486-rumqopg0	170	4	to	to	IN
cord-312486-rumqopg0	170	5	mechanisms	mechanism	NNS
cord-312486-rumqopg0	170	6	of	of	IN
cord-312486-rumqopg0	170	7	immune	immune	JJ
cord-312486-rumqopg0	170	8	evasion	evasion	NN
cord-312486-rumqopg0	170	9	,	,	,
cord-312486-rumqopg0	170	10	enhanced	enhance	VBN
cord-312486-rumqopg0	170	11	innate	innate	JJ
cord-312486-rumqopg0	170	12	immune	immune	JJ
cord-312486-rumqopg0	170	13	activation	activation	NN
cord-312486-rumqopg0	170	14	is	be	VBZ
cord-312486-rumqopg0	170	15	central	central	JJ
cord-312486-rumqopg0	170	16	to	to	IN
cord-312486-rumqopg0	170	17	the	the	DT
cord-312486-rumqopg0	170	18	morbidity	morbidity	NN
cord-312486-rumqopg0	170	19	and	and	CC
cord-312486-rumqopg0	170	20	mortality	mortality	NN
cord-312486-rumqopg0	170	21	of	of	IN
cord-312486-rumqopg0	170	22	COVID-19	covid-19	JJ
cord-312486-rumqopg0	170	23	patients	patient	NNS
cord-312486-rumqopg0	170	24	.	.	.
cord-312486-rumqopg0	171	1	Immune	immune	JJ
cord-312486-rumqopg0	171	2	evasion	evasion	NN
cord-312486-rumqopg0	171	3	seems	seem	VBZ
cord-312486-rumqopg0	171	4	to	to	TO
cord-312486-rumqopg0	171	5	characterize	characterize	VB
cord-312486-rumqopg0	171	6	the	the	DT
cord-312486-rumqopg0	171	7	first	first	JJ
cord-312486-rumqopg0	171	8	phase	phase	NN
cord-312486-rumqopg0	171	9	of	of	IN
cord-312486-rumqopg0	171	10	infection	infection	NN
cord-312486-rumqopg0	171	11	with	with	IN
cord-312486-rumqopg0	171	12	SARS	SARS	NNP
cord-312486-rumqopg0	171	13	-	-	HYPH
cord-312486-rumqopg0	171	14	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	172	1	and	and	CC
cord-312486-rumqopg0	172	2	this	this	DT
cord-312486-rumqopg0	172	3	is	be	VBZ
cord-312486-rumqopg0	172	4	associated	associate	VBN
cord-312486-rumqopg0	172	5	with	with	IN
cord-312486-rumqopg0	172	6	reduced	reduce	VBN
cord-312486-rumqopg0	172	7	innate	innate	JJ
cord-312486-rumqopg0	172	8	antiviral	antiviral	JJ
cord-312486-rumqopg0	172	9	immunity	immunity	NN
cord-312486-rumqopg0	172	10	.	.	.
cord-312486-rumqopg0	173	1	However	however	RB
cord-312486-rumqopg0	173	2	,	,	,
cord-312486-rumqopg0	173	3	approximately	approximately	RB
cord-312486-rumqopg0	173	4	twenty	twenty	CD
cord-312486-rumqopg0	173	5	percent	percent	NN
cord-312486-rumqopg0	173	6	of	of	IN
cord-312486-rumqopg0	173	7	infected	infected	JJ
cord-312486-rumqopg0	173	8	subjects	subject	NNS
cord-312486-rumqopg0	173	9	develop	develop	VBP
cord-312486-rumqopg0	173	10	an	an	DT
cord-312486-rumqopg0	173	11	excessive	excessive	JJ
cord-312486-rumqopg0	173	12	innate	innate	JJ
cord-312486-rumqopg0	173	13	immune	immune	JJ
cord-312486-rumqopg0	173	14	activation	activation	NN
cord-312486-rumqopg0	173	15	approximately	approximately	RB
cord-312486-rumqopg0	173	16	7	7	CD
cord-312486-rumqopg0	173	17	-	-	SYM
cord-312486-rumqopg0	173	18	10	10	CD
cord-312486-rumqopg0	173	19	days	day	NNS
cord-312486-rumqopg0	173	20	after	after	IN
cord-312486-rumqopg0	173	21	infection	infection	NN
cord-312486-rumqopg0	173	22	,	,	,
cord-312486-rumqopg0	173	23	which	which	WDT
cord-312486-rumqopg0	173	24	I	-PRON-	PRP
cord-312486-rumqopg0	173	25	argue	argue	VBP
cord-312486-rumqopg0	173	26	is	be	VBZ
cord-312486-rumqopg0	173	27	associated	associate	VBN
cord-312486-rumqopg0	173	28	only	only	RB
cord-312486-rumqopg0	173	29	marginally	marginally	RB
cord-312486-rumqopg0	173	30	,	,	,
cord-312486-rumqopg0	173	31	if	if	IN
cord-312486-rumqopg0	173	32	at	at	RB
cord-312486-rumqopg0	173	33	all	all	RB
cord-312486-rumqopg0	173	34	,	,	,
cord-312486-rumqopg0	173	35	with	with	IN
cord-312486-rumqopg0	173	36	viral	viral	JJ
cord-312486-rumqopg0	173	37	load	load	NN
cord-312486-rumqopg0	173	38	.	.	.
cord-312486-rumqopg0	174	1	Rather	rather	RB
cord-312486-rumqopg0	174	2	,	,	,
cord-312486-rumqopg0	174	3	the	the	DT
cord-312486-rumqopg0	174	4	massive	massive	JJ
cord-312486-rumqopg0	174	5	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	174	6	response	response	NN
cord-312486-rumqopg0	174	7	is	be	VBZ
cord-312486-rumqopg0	174	8	a	a	DT
cord-312486-rumqopg0	174	9	consequence	consequence	NN
cord-312486-rumqopg0	174	10	of	of	IN
cord-312486-rumqopg0	174	11	host	host	NN
cord-312486-rumqopg0	174	12	dysregulation	dysregulation	NN
cord-312486-rumqopg0	174	13	of	of	IN
cord-312486-rumqopg0	174	14	the	the	DT
cord-312486-rumqopg0	174	15	immune	immune	JJ
cord-312486-rumqopg0	174	16	system	system	NN
cord-312486-rumqopg0	174	17	.	.	.
cord-312486-rumqopg0	175	1	In	in	IN
cord-312486-rumqopg0	175	2	line	line	NN
cord-312486-rumqopg0	175	3	with	with	IN
cord-312486-rumqopg0	175	4	observations	observation	NNS
cord-312486-rumqopg0	175	5	in	in	IN
cord-312486-rumqopg0	175	6	SARS	SARS	NNP
cord-312486-rumqopg0	175	7	-	-	HYPH
cord-312486-rumqopg0	175	8	CoV-1	CoV-1	NNP
cord-312486-rumqopg0	175	9	[	[	-LRB-
cord-312486-rumqopg0	175	10	89	89	CD
cord-312486-rumqopg0	175	11	]	]	-RRB-
cord-312486-rumqopg0	175	12	,	,	,
cord-312486-rumqopg0	175	13	SARS	SARS	NNP
cord-312486-rumqopg0	175	14	-	-	HYPH
cord-312486-rumqopg0	175	15	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	175	16	induces	induce	VBZ
cord-312486-rumqopg0	175	17	a	a	DT
cord-312486-rumqopg0	175	18	robust	robust	JJ
cord-312486-rumqopg0	175	19	cytokine	cytokine	NN
cord-312486-rumqopg0	175	20	response	response	NN
cord-312486-rumqopg0	175	21	with	with	IN
cord-312486-rumqopg0	175	22	low	low	JJ
cord-312486-rumqopg0	175	23	levels	level	NNS
cord-312486-rumqopg0	175	24	of	of	IN
cord-312486-rumqopg0	175	25	IFN	IFN	NNP
cord-312486-rumqopg0	175	26	in	in	IN
cord-312486-rumqopg0	175	27	the	the	DT
cord-312486-rumqopg0	175	28	early	early	JJ
cord-312486-rumqopg0	175	29	phase	phase	NN
cord-312486-rumqopg0	175	30	,	,	,
cord-312486-rumqopg0	175	31	culminating	culminate	VBG
cord-312486-rumqopg0	175	32	in	in	IN
cord-312486-rumqopg0	175	33	improper	improper	JJ
cord-312486-rumqopg0	175	34	recruitment	recruitment	NN
cord-312486-rumqopg0	175	35	of	of	IN
cord-312486-rumqopg0	175	36	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	175	37	monocyte	monocyte	JJ
cord-312486-rumqopg0	175	38	-	-	HYPH
cord-312486-rumqopg0	175	39	macrophage	macrophage	NN
cord-312486-rumqopg0	175	40	and	and	CC
cord-312486-rumqopg0	175	41	neutrophil	neutrophil	NN
cord-312486-rumqopg0	175	42	populations	population	NNS
cord-312486-rumqopg0	175	43	into	into	IN
cord-312486-rumqopg0	175	44	target	target	NN
cord-312486-rumqopg0	175	45	organs	organ	NNS
cord-312486-rumqopg0	175	46	,	,	,
cord-312486-rumqopg0	175	47	resulting	result	VBG
cord-312486-rumqopg0	175	48	in	in	IN
cord-312486-rumqopg0	175	49	further	further	JJ
cord-312486-rumqopg0	175	50	cytokine	cytokine	NN
cord-312486-rumqopg0	175	51	production	production	NN
cord-312486-rumqopg0	175	52	[	[	-LRB-
cord-312486-rumqopg0	175	53	73	73	CD
cord-312486-rumqopg0	175	54	]	]	-RRB-
cord-312486-rumqopg0	175	55	.	.	.
cord-312486-rumqopg0	176	1	A	a	DT
cord-312486-rumqopg0	176	2	recurring	recur	VBG
cord-312486-rumqopg0	176	3	theme	theme	NN
cord-312486-rumqopg0	176	4	in	in	IN
cord-312486-rumqopg0	177	1	COVID-19	covid-19	JJ
cord-312486-rumqopg0	177	2	pathogenesis	pathogenesis	NN
cord-312486-rumqopg0	177	3	is	be	VBZ
cord-312486-rumqopg0	177	4	that	that	IN
cord-312486-rumqopg0	177	5	components	component	NNS
cord-312486-rumqopg0	177	6	of	of	IN
cord-312486-rumqopg0	177	7	the	the	DT
cord-312486-rumqopg0	177	8	immune	immune	JJ
cord-312486-rumqopg0	177	9	system	system	NN
cord-312486-rumqopg0	177	10	that	that	WDT
cord-312486-rumqopg0	177	11	are	be	VBP
cord-312486-rumqopg0	177	12	generally	generally	RB
cord-312486-rumqopg0	177	13	thought	think	VBN
cord-312486-rumqopg0	177	14	to	to	TO
cord-312486-rumqopg0	177	15	contribute	contribute	VB
cord-312486-rumqopg0	177	16	to	to	IN
cord-312486-rumqopg0	177	17	antiviral	antiviral	JJ
cord-312486-rumqopg0	177	18	host	host	NN
cord-312486-rumqopg0	177	19	defense	defense	NN
cord-312486-rumqopg0	177	20	end	end	VB
cord-312486-rumqopg0	177	21	up	up	RP
cord-312486-rumqopg0	177	22	promoting	promote	VBG
cord-312486-rumqopg0	177	23	disease	disease	NN
cord-312486-rumqopg0	177	24	severity	severity	NN
cord-312486-rumqopg0	177	25	.	.	.
cord-312486-rumqopg0	178	1	Typically	typically	RB
cord-312486-rumqopg0	178	2	,	,	,
cord-312486-rumqopg0	178	3	the	the	DT
cord-312486-rumqopg0	178	4	complement	complement	NN
cord-312486-rumqopg0	178	5	system	system	NN
cord-312486-rumqopg0	178	6	can	can	MD
cord-312486-rumqopg0	178	7	efficiently	efficiently	RB
cord-312486-rumqopg0	178	8	recognize	recognize	VB
cord-312486-rumqopg0	178	9	and	and	CC
cord-312486-rumqopg0	178	10	eliminate	eliminate	VB
cord-312486-rumqopg0	178	11	viral	viral	JJ
cord-312486-rumqopg0	178	12	pathogens	pathogen	NNS
cord-312486-rumqopg0	178	13	by	by	IN
cord-312486-rumqopg0	178	14	opsonizing	opsonize	VBG
cord-312486-rumqopg0	178	15	viruses	virus	NNS
cord-312486-rumqopg0	178	16	and	and	CC
cord-312486-rumqopg0	178	17	virus	virus	NN
cord-312486-rumqopg0	178	18	infected	infect	VBN
cord-312486-rumqopg0	178	19	cells	cell	NNS
cord-312486-rumqopg0	178	20	,	,	,
cord-312486-rumqopg0	178	21	inducing	induce	VBG
cord-312486-rumqopg0	178	22	an	an	DT
cord-312486-rumqopg0	178	23	antiviral	antiviral	JJ
cord-312486-rumqopg0	178	24	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	178	25	state	state	NN
cord-312486-rumqopg0	178	26	,	,	,
cord-312486-rumqopg0	178	27	increasing	increase	VBG
cord-312486-rumqopg0	178	28	virus	virus	NN
cord-312486-rumqopg0	178	29	-	-	HYPH
cord-312486-rumqopg0	178	30	specific	specific	JJ
cord-312486-rumqopg0	178	31	immune	immune	JJ
cord-312486-rumqopg0	178	32	responses	response	NNS
cord-312486-rumqopg0	178	33	,	,	,
cord-312486-rumqopg0	178	34	and	and	CC
cord-312486-rumqopg0	178	35	neutralizing	neutralize	VBG
cord-312486-rumqopg0	178	36	cell	cell	NN
cord-312486-rumqopg0	178	37	-	-	HYPH
cord-312486-rumqopg0	178	38	free	free	JJ
cord-312486-rumqopg0	178	39	viruses	virus	NNS
cord-312486-rumqopg0	178	40	[	[	-LRB-
cord-312486-rumqopg0	178	41	90	90	CD
cord-312486-rumqopg0	178	42	]	]	-RRB-
cord-312486-rumqopg0	178	43	.	.	.
cord-312486-rumqopg0	179	1	However	however	RB
cord-312486-rumqopg0	179	2	,	,	,
cord-312486-rumqopg0	179	3	the	the	DT
cord-312486-rumqopg0	179	4	activation	activation	NN
cord-312486-rumqopg0	179	5	of	of	IN
cord-312486-rumqopg0	179	6	multiple	multiple	JJ
cord-312486-rumqopg0	179	7	complement	complement	NN
cord-312486-rumqopg0	179	8	pathways	pathway	NNS
cord-312486-rumqopg0	179	9	,	,	,
cord-312486-rumqopg0	179	10	dysregulated	dysregulated	JJ
cord-312486-rumqopg0	179	11	neutrophil	neutrophil	NN
cord-312486-rumqopg0	179	12	responses	response	NNS
cord-312486-rumqopg0	179	13	,	,	,
cord-312486-rumqopg0	179	14	endothelial	endothelial	JJ
cord-312486-rumqopg0	179	15	injury	injury	NN
cord-312486-rumqopg0	179	16	,	,	,
cord-312486-rumqopg0	179	17	and	and	CC
cord-312486-rumqopg0	179	18	hypercoagulability	hypercoagulability	NN
cord-312486-rumqopg0	179	19	appear	appear	VBP
cord-312486-rumqopg0	179	20	to	to	TO
cord-312486-rumqopg0	179	21	be	be	VB
cord-312486-rumqopg0	179	22	interlinked	interlink	VBN
cord-312486-rumqopg0	179	23	with	with	IN
cord-312486-rumqopg0	179	24	SARS	SARS	NNP
cord-312486-rumqopg0	179	25	-	-	HYPH
cord-312486-rumqopg0	179	26	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	179	27	infection	infection	NN
cord-312486-rumqopg0	179	28	and	and	CC
cord-312486-rumqopg0	179	29	instead	instead	RB
cord-312486-rumqopg0	179	30	serve	serve	VB
cord-312486-rumqopg0	179	31	to	to	TO
cord-312486-rumqopg0	179	32	drive	drive	VB
cord-312486-rumqopg0	179	33	the	the	DT
cord-312486-rumqopg0	179	34	severity	severity	NN
cord-312486-rumqopg0	179	35	of	of	IN
cord-312486-rumqopg0	179	36	the	the	DT
cord-312486-rumqopg0	179	37	disease	disease	NN
cord-312486-rumqopg0	179	38	[	[	-LRB-
cord-312486-rumqopg0	179	39	91	91	CD
cord-312486-rumqopg0	179	40	]	]	-RRB-
cord-312486-rumqopg0	179	41	.	.	.
cord-312486-rumqopg0	180	1	The	the	DT
cord-312486-rumqopg0	180	2	functional	functional	JJ
cord-312486-rumqopg0	180	3	importance	importance	NN
cord-312486-rumqopg0	180	4	of	of	IN
cord-312486-rumqopg0	180	5	complement	complement	JJ
cord-312486-rumqopg0	180	6	activation	activation	NN
cord-312486-rumqopg0	180	7	in	in	IN
cord-312486-rumqopg0	180	8	CoV	CoV	NNP
cord-312486-rumqopg0	180	9	was	be	VBD
cord-312486-rumqopg0	180	10	tested	test	VBN
cord-312486-rumqopg0	180	11	in	in	IN
cord-312486-rumqopg0	180	12	C3	C3	NNP
cord-312486-rumqopg0	180	13	KO	KO	NNP
cord-312486-rumqopg0	180	14	mice	mouse	NNS
cord-312486-rumqopg0	180	15	infected	infect	VBN
cord-312486-rumqopg0	180	16	with	with	IN
cord-312486-rumqopg0	180	17	SARS	SARS	NNP
cord-312486-rumqopg0	180	18	-	-	HYPH
cord-312486-rumqopg0	180	19	CoV-1	CoV-1	NNP
cord-312486-rumqopg0	180	20	[	[	-LRB-
cord-312486-rumqopg0	180	21	92	92	CD
cord-312486-rumqopg0	180	22	]	]	-RRB-
cord-312486-rumqopg0	180	23	.	.	.
cord-312486-rumqopg0	181	1	The	the	DT
cord-312486-rumqopg0	181	2	studies	study	NNS
cord-312486-rumqopg0	181	3	showed	show	VBD
cord-312486-rumqopg0	181	4	that	that	IN
cord-312486-rumqopg0	181	5	complement	complement	JJ
cord-312486-rumqopg0	181	6	activation	activation	NN
cord-312486-rumqopg0	181	7	regulates	regulate	VBZ
cord-312486-rumqopg0	181	8	a	a	DT
cord-312486-rumqopg0	181	9	systemic	systemic	JJ
cord-312486-rumqopg0	181	10	proinflammatory	proinflammatory	JJ
cord-312486-rumqopg0	181	11	response	response	NN
cord-312486-rumqopg0	181	12	and	and	CC
cord-312486-rumqopg0	181	13	removal	removal	NN
cord-312486-rumqopg0	181	14	of	of	IN
cord-312486-rumqopg0	181	15	C3	C3	NNP
cord-312486-rumqopg0	181	16	signaling	signal	VBG
cord-312486-rumqopg0	181	17	reduced	reduce	VBN
cord-312486-rumqopg0	181	18	lung	lung	NN
cord-312486-rumqopg0	181	19	injury	injury	NN
cord-312486-rumqopg0	181	20	and	and	CC
cord-312486-rumqopg0	181	21	respiratory	respiratory	JJ
cord-312486-rumqopg0	181	22	dysfunction	dysfunction	NN
cord-312486-rumqopg0	181	23	,	,	,
cord-312486-rumqopg0	181	24	despite	despite	IN
cord-312486-rumqopg0	181	25	equivalent	equivalent	JJ
cord-312486-rumqopg0	181	26	viral	viral	JJ
cord-312486-rumqopg0	181	27	loads	load	NNS
cord-312486-rumqopg0	181	28	present	present	JJ
cord-312486-rumqopg0	181	29	in	in	IN
cord-312486-rumqopg0	181	30	the	the	DT
cord-312486-rumqopg0	181	31	lungs	lung	NNS
cord-312486-rumqopg0	181	32	.	.	.
cord-312486-rumqopg0	182	1	This	this	DT
cord-312486-rumqopg0	182	2	was	be	VBD
cord-312486-rumqopg0	182	3	associated	associate	VBN
cord-312486-rumqopg0	182	4	with	with	IN
cord-312486-rumqopg0	182	5	reduced	reduce	VBN
cord-312486-rumqopg0	182	6	lung	lung	NN
cord-312486-rumqopg0	182	7	infiltration	infiltration	NN
cord-312486-rumqopg0	182	8	of	of	IN
cord-312486-rumqopg0	182	9	neutrophils	neutrophil	NNS
cord-312486-rumqopg0	182	10	and	and	CC
cord-312486-rumqopg0	182	11	monocytes	monocyte	NNS
cord-312486-rumqopg0	182	12	and	and	CC
cord-312486-rumqopg0	182	13	lower	low	JJR
cord-312486-rumqopg0	182	14	cytokine	cytokine	NN
cord-312486-rumqopg0	182	15	and	and	CC
cord-312486-rumqopg0	182	16	chemokine	chemokine	NN
cord-312486-rumqopg0	182	17	levels	level	NNS
cord-312486-rumqopg0	182	18	in	in	IN
cord-312486-rumqopg0	182	19	both	both	CC
cord-312486-rumqopg0	182	20	the	the	DT
cord-312486-rumqopg0	182	21	lungs	lung	NNS
cord-312486-rumqopg0	182	22	and	and	CC
cord-312486-rumqopg0	182	23	sera	sera	NNP
cord-312486-rumqopg0	182	24	[	[	-LRB-
cord-312486-rumqopg0	182	25	92	92	CD
cord-312486-rumqopg0	182	26	]	]	-RRB-
cord-312486-rumqopg0	182	27	.	.	.
cord-312486-rumqopg0	183	1	Lung	lung	NN
cord-312486-rumqopg0	183	2	biopsy	biopsy	NN
cord-312486-rumqopg0	183	3	samples	sample	NNS
cord-312486-rumqopg0	183	4	from	from	IN
cord-312486-rumqopg0	183	5	patients	patient	NNS
cord-312486-rumqopg0	183	6	with	with	IN
cord-312486-rumqopg0	183	7	severe	severe	JJ
cord-312486-rumqopg0	183	8	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	183	9	show	show	NN
cord-312486-rumqopg0	183	10	widespread	widespread	JJ
cord-312486-rumqopg0	183	11	complement	complement	NN
cord-312486-rumqopg0	183	12	activation	activation	NN
cord-312486-rumqopg0	183	13	characterized	characterize	VBN
cord-312486-rumqopg0	183	14	by	by	IN
cord-312486-rumqopg0	183	15	C3a	C3a	NNP
cord-312486-rumqopg0	183	16	generation	generation	NN
cord-312486-rumqopg0	183	17	and	and	CC
cord-312486-rumqopg0	183	18	C3-fragment	c3-fragment	NN
cord-312486-rumqopg0	183	19	deposition	deposition	NN
cord-312486-rumqopg0	183	20	[	[	-LRB-
cord-312486-rumqopg0	183	21	93	93	CD
cord-312486-rumqopg0	183	22	]	]	-RRB-
cord-312486-rumqopg0	183	23	.	.	.
cord-312486-rumqopg0	184	1	The	the	DT
cord-312486-rumqopg0	184	2	host	host	NN
cord-312486-rumqopg0	184	3	complement	complement	NN
cord-312486-rumqopg0	184	4	activator	activator	NN
cord-312486-rumqopg0	184	5	MASP2	MASP2	NNP
cord-312486-rumqopg0	184	6	,	,	,
cord-312486-rumqopg0	184	7	the	the	DT
cord-312486-rumqopg0	184	8	key	key	JJ
cord-312486-rumqopg0	184	9	serine	serine	NN
cord-312486-rumqopg0	184	10	protease	protease	NN
cord-312486-rumqopg0	184	11	in	in	IN
cord-312486-rumqopg0	184	12	the	the	DT
cord-312486-rumqopg0	184	13	lectin	lectin	NN
cord-312486-rumqopg0	184	14	pathway	pathway	NN
cord-312486-rumqopg0	184	15	of	of	IN
cord-312486-rumqopg0	184	16	complement	complement	JJ
cord-312486-rumqopg0	184	17	activation	activation	NN
cord-312486-rumqopg0	184	18	,	,	,
cord-312486-rumqopg0	184	19	was	be	VBD
cord-312486-rumqopg0	184	20	identified	identify	VBN
cord-312486-rumqopg0	184	21	as	as	IN
cord-312486-rumqopg0	184	22	a	a	DT
cord-312486-rumqopg0	184	23	target	target	NN
cord-312486-rumqopg0	184	24	of	of	IN
cord-312486-rumqopg0	184	25	the	the	DT
cord-312486-rumqopg0	184	26	N	N	NNP
cord-312486-rumqopg0	184	27	(	(	-LRB-
cord-312486-rumqopg0	184	28	nucleoprotein	nucleoprotein	NNP
cord-312486-rumqopg0	184	29	)	)	-RRB-
cord-312486-rumqopg0	184	30	protein	protein	NN
cord-312486-rumqopg0	184	31	of	of	IN
cord-312486-rumqopg0	184	32	SARS	SARS	NNP
cord-312486-rumqopg0	184	33	-	-	HYPH
cord-312486-rumqopg0	184	34	CoV-1	CoV-1	NNP
cord-312486-rumqopg0	184	35	,	,	,
cord-312486-rumqopg0	184	36	MERS	MERS	NNP
cord-312486-rumqopg0	184	37	-	-	HYPH
cord-312486-rumqopg0	184	38	CoV	CoV	NNP
cord-312486-rumqopg0	184	39	,	,	,
cord-312486-rumqopg0	184	40	and	and	CC
cord-312486-rumqopg0	184	41	SARS	SARS	NNP
cord-312486-rumqopg0	184	42	-	-	HYPH
cord-312486-rumqopg0	184	43	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	184	44	,	,	,
cord-312486-rumqopg0	184	45	resulting	result	VBG
cord-312486-rumqopg0	184	46	in	in	IN
cord-312486-rumqopg0	184	47	aberrant	aberrant	JJ
cord-312486-rumqopg0	184	48	complement	complement	NN
cord-312486-rumqopg0	184	49	activation	activation	NN
cord-312486-rumqopg0	184	50	and	and	CC
cord-312486-rumqopg0	184	51	aggravated	aggravate	VBN
cord-312486-rumqopg0	184	52	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	184	53	lung	lung	NN
cord-312486-rumqopg0	184	54	injury	injury	NN
cord-312486-rumqopg0	184	55	.	.	.
cord-312486-rumqopg0	185	1	In	in	IN
cord-312486-rumqopg0	185	2	mice	mouse	NNS
cord-312486-rumqopg0	185	3	,	,	,
cord-312486-rumqopg0	185	4	lung	lung	NN
cord-312486-rumqopg0	185	5	injury	injury	NN
cord-312486-rumqopg0	185	6	induced	induce	VBN
cord-312486-rumqopg0	185	7	by	by	IN
cord-312486-rumqopg0	185	8	SARS	SARS	NNP
cord-312486-rumqopg0	185	9	-	-	HYPH
cord-312486-rumqopg0	185	10	CoV-1	CoV-1	NNPS
cord-312486-rumqopg0	185	11	or	or	CC
cord-312486-rumqopg0	185	12	MERS	MERS	NNP
cord-312486-rumqopg0	185	13	-	-	HYPH
cord-312486-rumqopg0	185	14	CoV	CoV	NNP
cord-312486-rumqopg0	185	15	N	n	CD
cord-312486-rumqopg0	185	16	protein	protein	NN
cord-312486-rumqopg0	185	17	was	be	VBD
cord-312486-rumqopg0	185	18	attenuated	attenuate	VBN
cord-312486-rumqopg0	185	19	when	when	WRB
cord-312486-rumqopg0	185	20	its	-PRON-	PRP$
cord-312486-rumqopg0	185	21	MASP2-binding	MASP2-binding	NNP
cord-312486-rumqopg0	185	22	motif	motif	NN
cord-312486-rumqopg0	185	23	was	be	VBD
cord-312486-rumqopg0	185	24	altered	alter	VBN
cord-312486-rumqopg0	185	25	,	,	,
cord-312486-rumqopg0	185	26	when	when	WRB
cord-312486-rumqopg0	185	27	MASP2	MASP2	NNP
cord-312486-rumqopg0	185	28	was	be	VBD
cord-312486-rumqopg0	185	29	genetically	genetically	RB
cord-312486-rumqopg0	185	30	knocked	knock	VBN
cord-312486-rumqopg0	185	31	out	out	RP
cord-312486-rumqopg0	185	32	,	,	,
cord-312486-rumqopg0	185	33	or	or	CC
cord-312486-rumqopg0	185	34	when	when	WRB
cord-312486-rumqopg0	185	35	the	the	DT
cord-312486-rumqopg0	185	36	MASP2-N	MASP2-N	NNP
cord-312486-rumqopg0	185	37	protein	protein	NN
cord-312486-rumqopg0	185	38	interaction	interaction	NN
cord-312486-rumqopg0	185	39	was	be	VBD
cord-312486-rumqopg0	185	40	pharmacologically	pharmacologically	RB
cord-312486-rumqopg0	185	41	blocked	block	VBN
cord-312486-rumqopg0	185	42	[	[	-LRB-
cord-312486-rumqopg0	185	43	93	93	CD
cord-312486-rumqopg0	185	44	]	]	-RRB-
cord-312486-rumqopg0	185	45	.	.	.
cord-312486-rumqopg0	186	1	Earlier	early	RBR
cord-312486-rumqopg0	186	2	I	-PRON-	PRP
cord-312486-rumqopg0	186	3	have	have	VBP
cord-312486-rumqopg0	186	4	discussed	discuss	VBN
cord-312486-rumqopg0	186	5	the	the	DT
cord-312486-rumqopg0	186	6	GWAS	GWAS	NNP
cord-312486-rumqopg0	186	7	that	that	WDT
cord-312486-rumqopg0	186	8	established	establish	VBD
cord-312486-rumqopg0	186	9	significant	significant	JJ
cord-312486-rumqopg0	186	10	association	association	NN
cord-312486-rumqopg0	186	11	between	between	IN
cord-312486-rumqopg0	186	12	severe	severe	JJ
cord-312486-rumqopg0	186	13	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	186	14	and	and	CC
cord-312486-rumqopg0	186	15	the	the	DT
cord-312486-rumqopg0	186	16	ABO	ABO	NNP
cord-312486-rumqopg0	186	17	blood	blood	NN
cord-312486-rumqopg0	186	18	type	type	NN
cord-312486-rumqopg0	186	19	cluster	cluster	NN
cord-312486-rumqopg0	186	20	[	[	-LRB-
cord-312486-rumqopg0	186	21	62	62	CD
cord-312486-rumqopg0	186	22	]	]	-RRB-
cord-312486-rumqopg0	186	23	.	.	.
cord-312486-rumqopg0	187	1	Having	have	VBG
cord-312486-rumqopg0	187	2	blood	blood	NN
cord-312486-rumqopg0	187	3	type	type	NN
cord-312486-rumqopg0	187	4	A	a	NN
cord-312486-rumqopg0	187	5	was	be	VBD
cord-312486-rumqopg0	187	6	linked	link	VBN
cord-312486-rumqopg0	187	7	to	to	IN
cord-312486-rumqopg0	187	8	an	an	DT
cord-312486-rumqopg0	187	9	approximately	approximately	RB
cord-312486-rumqopg0	187	10	forty	forty	CD
cord-312486-rumqopg0	187	11	-	-	HYPH
cord-312486-rumqopg0	187	12	five	five	CD
cord-312486-rumqopg0	187	13	percent	percent	NN
cord-312486-rumqopg0	187	14	increase	increase	NN
cord-312486-rumqopg0	187	15	in	in	IN
cord-312486-rumqopg0	187	16	the	the	DT
cord-312486-rumqopg0	187	17	likelihood	likelihood	NN
cord-312486-rumqopg0	187	18	that	that	IN
cord-312486-rumqopg0	187	19	a	a	DT
cord-312486-rumqopg0	187	20	patient	patient	NN
cord-312486-rumqopg0	187	21	would	would	MD
cord-312486-rumqopg0	187	22	develop	develop	VB
cord-312486-rumqopg0	187	23	J	J	NNP
cord-312486-rumqopg0	187	24	o	o	NN
cord-312486-rumqopg0	187	25	u	u	NN
cord-312486-rumqopg0	187	26	r	r	NN
cord-312486-rumqopg0	187	27	n	n	NN
cord-312486-rumqopg0	187	28	a	a	DT
cord-312486-rumqopg0	187	29	l	l	NN
cord-312486-rumqopg0	187	30	P	p	NN
cord-312486-rumqopg0	187	31	r	r	NN
cord-312486-rumqopg0	187	32	e	e	NN
cord-312486-rumqopg0	187	33	-p	-p	NN
cord-312486-rumqopg0	187	34	r	r	NN
cord-312486-rumqopg0	187	35	o	o	NN
cord-312486-rumqopg0	187	36	o	o	NN
cord-312486-rumqopg0	187	37	f	f	NN
cord-312486-rumqopg0	187	38	respiratory	respiratory	JJ
cord-312486-rumqopg0	187	39	failure	failure	NN
cord-312486-rumqopg0	187	40	,	,	,
cord-312486-rumqopg0	187	41	while	while	IN
cord-312486-rumqopg0	187	42	subjects	subject	NNS
cord-312486-rumqopg0	187	43	with	with	IN
cord-312486-rumqopg0	187	44	blood	blood	NN
cord-312486-rumqopg0	187	45	group	group	NN
cord-312486-rumqopg0	187	46	O	o	NN
cord-312486-rumqopg0	187	47	were	be	VBD
cord-312486-rumqopg0	187	48	at	at	IN
cord-312486-rumqopg0	187	49	a	a	DT
cord-312486-rumqopg0	187	50	thirty	thirty	CD
cord-312486-rumqopg0	187	51	-	-	HYPH
cord-312486-rumqopg0	187	52	five	five	CD
cord-312486-rumqopg0	187	53	percent	percent	NN
cord-312486-rumqopg0	187	54	decreased	decrease	VBD
cord-312486-rumqopg0	187	55	risk	risk	NN
cord-312486-rumqopg0	187	56	for	for	IN
cord-312486-rumqopg0	187	57	respiratory	respiratory	JJ
cord-312486-rumqopg0	187	58	failure	failure	NN
cord-312486-rumqopg0	187	59	.	.	.
cord-312486-rumqopg0	188	1	A	a	DT
cord-312486-rumqopg0	188	2	possible	possible	JJ
cord-312486-rumqopg0	188	3	mechanistic	mechanistic	JJ
cord-312486-rumqopg0	188	4	explanation	explanation	NN
cord-312486-rumqopg0	188	5	could	could	MD
cord-312486-rumqopg0	188	6	be	be	VB
cord-312486-rumqopg0	188	7	that	that	DT
cord-312486-rumqopg0	188	8	type	type	NN
cord-312486-rumqopg0	188	9	O	o	NN
cord-312486-rumqopg0	188	10	patients	patient	NNS
cord-312486-rumqopg0	188	11	harbor	harbor	VBP
cord-312486-rumqopg0	188	12	both	both	DT
cord-312486-rumqopg0	188	13	anti	anti	JJ
cord-312486-rumqopg0	188	14	-	-	JJ
cord-312486-rumqopg0	188	15	A	a	JJ
cord-312486-rumqopg0	188	16	and	and	CC
cord-312486-rumqopg0	188	17	anti	anti	JJ
cord-312486-rumqopg0	188	18	-	-	JJ
cord-312486-rumqopg0	188	19	B	b	JJ
cord-312486-rumqopg0	188	20	natural	natural	JJ
cord-312486-rumqopg0	188	21	IgM	IgM	NNP
cord-312486-rumqopg0	188	22	Abs	Abs	NNP
cord-312486-rumqopg0	188	23	.	.	.
cord-312486-rumqopg0	189	1	These	these	DT
cord-312486-rumqopg0	189	2	may	may	MD
cord-312486-rumqopg0	189	3	help	help	VB
cord-312486-rumqopg0	189	4	reduce	reduce	VB
cord-312486-rumqopg0	189	5	the	the	DT
cord-312486-rumqopg0	189	6	viral	viral	JJ
cord-312486-rumqopg0	189	7	load	load	NN
cord-312486-rumqopg0	189	8	of	of	IN
cord-312486-rumqopg0	189	9	their	-PRON-	PRP$
cord-312486-rumqopg0	189	10	hosts	host	NNS
cord-312486-rumqopg0	189	11	due	due	JJ
cord-312486-rumqopg0	189	12	to	to	IN
cord-312486-rumqopg0	189	13	early	early	JJ
cord-312486-rumqopg0	189	14	activation	activation	NN
cord-312486-rumqopg0	189	15	of	of	IN
cord-312486-rumqopg0	189	16	the	the	DT
cord-312486-rumqopg0	189	17	classical	classical	JJ
cord-312486-rumqopg0	189	18	complement	complement	NN
cord-312486-rumqopg0	189	19	pathway	pathway	NN
cord-312486-rumqopg0	189	20	followed	follow	VBN
cord-312486-rumqopg0	189	21	by	by	IN
cord-312486-rumqopg0	189	22	viral	viral	JJ
cord-312486-rumqopg0	189	23	clearance	clearance	NN
cord-312486-rumqopg0	189	24	.	.	.
cord-312486-rumqopg0	190	1	Such	such	JJ
cord-312486-rumqopg0	190	2	mechanism	mechanism	NN
cord-312486-rumqopg0	190	3	has	have	VBZ
cord-312486-rumqopg0	190	4	been	be	VBN
cord-312486-rumqopg0	190	5	shown	show	VBN
cord-312486-rumqopg0	190	6	to	to	TO
cord-312486-rumqopg0	190	7	work	work	VB
cord-312486-rumqopg0	190	8	in	in	IN
cord-312486-rumqopg0	190	9	vitro	vitro	FW
cord-312486-rumqopg0	190	10	,	,	,
cord-312486-rumqopg0	190	11	using	use	VBG
cord-312486-rumqopg0	190	12	measles	measle	NNS
cord-312486-rumqopg0	190	13	virus	virus	NN
cord-312486-rumqopg0	190	14	produced	produce	VBN
cord-312486-rumqopg0	190	15	in	in	IN
cord-312486-rumqopg0	190	16	cells	cell	NNS
cord-312486-rumqopg0	190	17	engineered	engineer	VBN
cord-312486-rumqopg0	190	18	to	to	TO
cord-312486-rumqopg0	190	19	express	express	VB
cord-312486-rumqopg0	190	20	only	only	RB
cord-312486-rumqopg0	190	21	A	a	NN
cord-312486-rumqopg0	190	22	-	-	HYPH
cord-312486-rumqopg0	190	23	type	type	NN
cord-312486-rumqopg0	190	24	,	,	,
cord-312486-rumqopg0	190	25	B	b	NN
cord-312486-rumqopg0	190	26	-	-	HYPH
cord-312486-rumqopg0	190	27	type	type	NN
cord-312486-rumqopg0	190	28	or	or	CC
cord-312486-rumqopg0	190	29	O	o	NN
cord-312486-rumqopg0	190	30	-	-	HYPH
cord-312486-rumqopg0	190	31	type	type	NN
cord-312486-rumqopg0	190	32	carbohydrate	carbohydrate	NN
cord-312486-rumqopg0	190	33	epitopes	epitope	NNS
cord-312486-rumqopg0	190	34	.	.	.
cord-312486-rumqopg0	191	1	Measles	measles	NN
cord-312486-rumqopg0	191	2	virus	virus	NN
cord-312486-rumqopg0	191	3	was	be	VBD
cord-312486-rumqopg0	191	4	neutralized	neutralize	VBN
cord-312486-rumqopg0	191	5	by	by	IN
cord-312486-rumqopg0	191	6	human	human	JJ
cord-312486-rumqopg0	191	7	serum	serum	NN
cord-312486-rumqopg0	191	8	(	(	-LRB-
cord-312486-rumqopg0	191	9	that	that	WDT
cord-312486-rumqopg0	191	10	did	do	VBD
cord-312486-rumqopg0	191	11	not	not	RB
cord-312486-rumqopg0	191	12	contain	contain	VB
cord-312486-rumqopg0	191	13	anti	anti	JJ
cord-312486-rumqopg0	191	14	-	-	JJ
cord-312486-rumqopg0	191	15	measles	measles	JJ
cord-312486-rumqopg0	191	16	Ab	Ab	NNP
cord-312486-rumqopg0	191	17	)	)	-RRB-
cord-312486-rumqopg0	191	18	,	,	,
cord-312486-rumqopg0	191	19	utilizing	utilize	VBG
cord-312486-rumqopg0	191	20	natural	natural	JJ
cord-312486-rumqopg0	191	21	Abs	Abs	NNP
cord-312486-rumqopg0	191	22	against	against	IN
cord-312486-rumqopg0	191	23	the	the	DT
cord-312486-rumqopg0	191	24	A	a	NN
cord-312486-rumqopg0	191	25	and	and	CC
cord-312486-rumqopg0	191	26	B	b	NN
cord-312486-rumqopg0	191	27	antigens	antigen	NNS
cord-312486-rumqopg0	191	28	in	in	IN
cord-312486-rumqopg0	191	29	a	a	DT
cord-312486-rumqopg0	191	30	strictly	strictly	RB
cord-312486-rumqopg0	191	31	complement	complement	NN
cord-312486-rumqopg0	191	32	-	-	HYPH
cord-312486-rumqopg0	191	33	dependent	dependent	JJ
cord-312486-rumqopg0	191	34	manner	manner	NN
cord-312486-rumqopg0	191	35	[	[	-LRB-
cord-312486-rumqopg0	191	36	94	94	CD
cord-312486-rumqopg0	191	37	]	]	-RRB-
cord-312486-rumqopg0	191	38	.	.	.
cord-312486-rumqopg0	192	1	These	these	DT
cord-312486-rumqopg0	192	2	observations	observation	NNS
cord-312486-rumqopg0	192	3	support	support	VBP
cord-312486-rumqopg0	192	4	a	a	DT
cord-312486-rumqopg0	192	5	role	role	NN
cord-312486-rumqopg0	192	6	for	for	IN
cord-312486-rumqopg0	192	7	the	the	DT
cord-312486-rumqopg0	192	8	complement	complement	JJ
cord-312486-rumqopg0	192	9	system	system	NN
cord-312486-rumqopg0	192	10	in	in	IN
cord-312486-rumqopg0	192	11	enabling	enable	VBG
cord-312486-rumqopg0	192	12	natural	natural	JJ
cord-312486-rumqopg0	192	13	ABO	ABO	NNP
cord-312486-rumqopg0	192	14	group	group	NN
cord-312486-rumqopg0	192	15	Abs	Abs	NNP
cord-312486-rumqopg0	192	16	as	as	IN
cord-312486-rumqopg0	192	17	first	first	JJ
cord-312486-rumqopg0	192	18	line	line	NN
cord-312486-rumqopg0	192	19	innate	innate	JJ
cord-312486-rumqopg0	192	20	immune	immune	JJ
cord-312486-rumqopg0	192	21	defense	defense	NN
cord-312486-rumqopg0	192	22	to	to	IN
cord-312486-rumqopg0	192	23	viral	viral	JJ
cord-312486-rumqopg0	192	24	infections	infection	NNS
cord-312486-rumqopg0	192	25	.	.	.
cord-312486-rumqopg0	193	1	Although	although	IN
cord-312486-rumqopg0	193	2	most	most	JJS
cord-312486-rumqopg0	193	3	early	early	JJ
cord-312486-rumqopg0	193	4	studies	study	NNS
cord-312486-rumqopg0	193	5	concentrated	concentrate	VBD
cord-312486-rumqopg0	193	6	on	on	IN
cord-312486-rumqopg0	193	7	the	the	DT
cord-312486-rumqopg0	193	8	lungs	lung	NNS
cord-312486-rumqopg0	193	9	as	as	IN
cord-312486-rumqopg0	193	10	the	the	DT
cord-312486-rumqopg0	193	11	target	target	NN
cord-312486-rumqopg0	193	12	organ	organ	NN
cord-312486-rumqopg0	193	13	in	in	IN
cord-312486-rumqopg0	193	14	SARS	SARS	NNP
cord-312486-rumqopg0	193	15	-	-	HYPH
cord-312486-rumqopg0	193	16	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	193	17	infection	infection	NN
cord-312486-rumqopg0	193	18	,	,	,
cord-312486-rumqopg0	193	19	it	-PRON-	PRP
cord-312486-rumqopg0	193	20	is	be	VBZ
cord-312486-rumqopg0	193	21	now	now	RB
cord-312486-rumqopg0	193	22	clear	clear	JJ
cord-312486-rumqopg0	193	23	that	that	IN
cord-312486-rumqopg0	193	24	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	193	25	has	have	VBZ
cord-312486-rumqopg0	193	26	a	a	DT
cord-312486-rumqopg0	193	27	wider	wide	JJR
cord-312486-rumqopg0	193	28	spectrum	spectrum	NN
cord-312486-rumqopg0	193	29	of	of	IN
cord-312486-rumqopg0	193	30	organ	organ	NN
cord-312486-rumqopg0	193	31	involvement	involvement	NN
cord-312486-rumqopg0	193	32	.	.	.
cord-312486-rumqopg0	194	1	This	this	DT
cord-312486-rumqopg0	194	2	may	may	MD
cord-312486-rumqopg0	194	3	be	be	VB
cord-312486-rumqopg0	194	4	a	a	DT
cord-312486-rumqopg0	194	5	result	result	NN
cord-312486-rumqopg0	194	6	of	of	IN
cord-312486-rumqopg0	194	7	the	the	DT
cord-312486-rumqopg0	194	8	broad	broad	JJ
cord-312486-rumqopg0	194	9	organ	organ	NN
cord-312486-rumqopg0	194	10	tropism	tropism	NN
cord-312486-rumqopg0	194	11	of	of	IN
cord-312486-rumqopg0	194	12	SARS	SARS	NNP
cord-312486-rumqopg0	194	13	-	-	HYPH
cord-312486-rumqopg0	194	14	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	194	15	,	,	,
cord-312486-rumqopg0	194	16	but	but	CC
cord-312486-rumqopg0	194	17	is	be	VBZ
cord-312486-rumqopg0	194	18	more	more	RBR
cord-312486-rumqopg0	194	19	likely	likely	JJ
cord-312486-rumqopg0	194	20	due	due	IN
cord-312486-rumqopg0	194	21	to	to	IN
cord-312486-rumqopg0	194	22	an	an	DT
cord-312486-rumqopg0	194	23	outof	outof	JJ
cord-312486-rumqopg0	194	24	-	-	HYPH
cord-312486-rumqopg0	194	25	control	control	NN
cord-312486-rumqopg0	194	26	host	host	NN
cord-312486-rumqopg0	194	27	immune	immune	JJ
cord-312486-rumqopg0	194	28	response	response	NN
cord-312486-rumqopg0	194	29	to	to	IN
cord-312486-rumqopg0	194	30	the	the	DT
cord-312486-rumqopg0	194	31	virus	virus	NN
cord-312486-rumqopg0	194	32	.	.	.
cord-312486-rumqopg0	195	1	Indeed	indeed	RB
cord-312486-rumqopg0	195	2	,	,	,
cord-312486-rumqopg0	195	3	evidence	evidence	NN
cord-312486-rumqopg0	195	4	is	be	VBZ
cord-312486-rumqopg0	195	5	accumulating	accumulate	VBG
cord-312486-rumqopg0	195	6	in	in	IN
cord-312486-rumqopg0	195	7	support	support	NN
cord-312486-rumqopg0	195	8	of	of	IN
cord-312486-rumqopg0	195	9	vascular	vascular	JJ
cord-312486-rumqopg0	195	10	cell	cell	NN
cord-312486-rumqopg0	195	11	dysfunction	dysfunction	NN
cord-312486-rumqopg0	195	12	in	in	IN
cord-312486-rumqopg0	195	13	multiple	multiple	JJ
cord-312486-rumqopg0	195	14	organs	organ	NNS
cord-312486-rumqopg0	195	15	during	during	IN
cord-312486-rumqopg0	195	16	SARS	SARS	NNP
cord-312486-rumqopg0	195	17	-	-	HYPH
cord-312486-rumqopg0	195	18	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	195	19	infection	infection	NN
cord-312486-rumqopg0	195	20	[	[	-LRB-
cord-312486-rumqopg0	195	21	95	95	CD
cord-312486-rumqopg0	195	22	]	]	-RRB-
cord-312486-rumqopg0	195	23	.	.	.
cord-312486-rumqopg0	196	1	First	first	RB
cord-312486-rumqopg0	196	2	,	,	,
cord-312486-rumqopg0	196	3	SARS	SARS	NNP
cord-312486-rumqopg0	196	4	-	-	HYPH
cord-312486-rumqopg0	196	5	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	196	6	is	be	VBZ
cord-312486-rumqopg0	196	7	able	able	JJ
cord-312486-rumqopg0	196	8	to	to	TO
cord-312486-rumqopg0	196	9	directly	directly	RB
cord-312486-rumqopg0	196	10	infect	infect	VB
cord-312486-rumqopg0	196	11	engineered	engineer	VBN
cord-312486-rumqopg0	196	12	human	human	JJ
cord-312486-rumqopg0	196	13	blood	blood	NN
cord-312486-rumqopg0	196	14	vessel	vessel	NN
cord-312486-rumqopg0	196	15	organoids	organoids	NNP
cord-312486-rumqopg0	196	16	[	[	-LRB-
cord-312486-rumqopg0	196	17	96	96	CD
cord-312486-rumqopg0	196	18	]	]	-RRB-
cord-312486-rumqopg0	196	19	.	.	.
cord-312486-rumqopg0	197	1	More	more	RBR
cord-312486-rumqopg0	197	2	importantly	importantly	RB
cord-312486-rumqopg0	197	3	,	,	,
cord-312486-rumqopg0	197	4	histopathological	histopathological	JJ
cord-312486-rumqopg0	197	5	evidence	evidence	NN
cord-312486-rumqopg0	197	6	of	of	IN
cord-312486-rumqopg0	197	7	vasculitis	vasculitis	NN
cord-312486-rumqopg0	197	8	,	,	,
cord-312486-rumqopg0	197	9	sometime	sometime	RB
cord-312486-rumqopg0	197	10	associated	associate	VBN
cord-312486-rumqopg0	197	11	with	with	IN
cord-312486-rumqopg0	197	12	viral	viral	JJ
cord-312486-rumqopg0	197	13	particles	particle	NNS
cord-312486-rumqopg0	197	14	,	,	,
cord-312486-rumqopg0	197	15	and	and	CC
cord-312486-rumqopg0	197	16	accumulation	accumulation	NN
cord-312486-rumqopg0	197	17	of	of	IN
cord-312486-rumqopg0	197	18	neutrophils	neutrophil	NNS
cord-312486-rumqopg0	197	19	and	and	CC
cord-312486-rumqopg0	197	20	monocytes	monocyte	NNS
cord-312486-rumqopg0	197	21	,	,	,
cord-312486-rumqopg0	197	22	and	and	CC
cord-312486-rumqopg0	197	23	even	even	RB
cord-312486-rumqopg0	197	24	lymphocytes	lymphocyte	NNS
cord-312486-rumqopg0	197	25	,	,	,
cord-312486-rumqopg0	197	26	in	in	IN
cord-312486-rumqopg0	197	27	the	the	DT
cord-312486-rumqopg0	197	28	wall	wall	NN
cord-312486-rumqopg0	197	29	of	of	IN
cord-312486-rumqopg0	197	30	blood	blood	NN
cord-312486-rumqopg0	197	31	vessels	vessel	NNS
cord-312486-rumqopg0	197	32	in	in	IN
cord-312486-rumqopg0	197	33	multiple	multiple	JJ
cord-312486-rumqopg0	197	34	organs	organ	NNS
cord-312486-rumqopg0	197	35	were	be	VBD
cord-312486-rumqopg0	197	36	described	describe	VBN
cord-312486-rumqopg0	197	37	[	[	-LRB-
cord-312486-rumqopg0	197	38	97	97	CD
cord-312486-rumqopg0	197	39	]	]	-RRB-
cord-312486-rumqopg0	197	40	.	.	.
cord-312486-rumqopg0	198	1	In	in	IN
cord-312486-rumqopg0	198	2	addition	addition	NN
cord-312486-rumqopg0	198	3	,	,	,
cord-312486-rumqopg0	198	4	endothelial	endothelial	JJ
cord-312486-rumqopg0	198	5	apoptosis	apoptosis	NN
cord-312486-rumqopg0	198	6	and	and	CC
cord-312486-rumqopg0	198	7	pyroptosis	pyroptosis	NN
cord-312486-rumqopg0	198	8	might	may	MD
cord-312486-rumqopg0	198	9	contribute	contribute	VB
cord-312486-rumqopg0	198	10	to	to	IN
cord-312486-rumqopg0	198	11	endothelial	endothelial	JJ
cord-312486-rumqopg0	198	12	cell	cell	NN
cord-312486-rumqopg0	198	13	injury	injury	NN
cord-312486-rumqopg0	198	14	.	.	.
cord-312486-rumqopg0	199	1	Similarly	similarly	RB
cord-312486-rumqopg0	199	2	,	,	,
cord-312486-rumqopg0	199	3	Bryce	Bryce	NNP
cord-312486-rumqopg0	199	4	et	et	NNP
cord-312486-rumqopg0	199	5	al	al	NNP
cord-312486-rumqopg0	199	6	.	.	NNP
cord-312486-rumqopg0	199	7	,	,	,
cord-312486-rumqopg0	199	8	found	find	VBD
cord-312486-rumqopg0	199	9	diffuse	diffuse	JJ
cord-312486-rumqopg0	199	10	vascular	vascular	JJ
cord-312486-rumqopg0	199	11	endothelial	endothelial	JJ
cord-312486-rumqopg0	199	12	inflammation	inflammation	NN
cord-312486-rumqopg0	199	13	with	with	IN
cord-312486-rumqopg0	199	14	micro	micro	JJ
cord-312486-rumqopg0	199	15	and	and	CC
cord-312486-rumqopg0	199	16	macro	macro	JJ
cord-312486-rumqopg0	199	17	vascular	vascular	JJ
cord-312486-rumqopg0	199	18	thrombosis	thrombosis	NN
cord-312486-rumqopg0	199	19	in	in	IN
cord-312486-rumqopg0	199	20	the	the	DT
cord-312486-rumqopg0	199	21	venous	venous	JJ
cord-312486-rumqopg0	199	22	and	and	CC
cord-312486-rumqopg0	199	23	arterial	arterial	JJ
cord-312486-rumqopg0	199	24	circulation	circulation	NN
cord-312486-rumqopg0	199	25	[	[	-LRB-
cord-312486-rumqopg0	199	26	98	98	CD
cord-312486-rumqopg0	199	27	]	]	-RRB-
cord-312486-rumqopg0	199	28	.	.	.
cord-312486-rumqopg0	200	1	The	the	DT
cord-312486-rumqopg0	200	2	vascular	vascular	JJ
cord-312486-rumqopg0	200	3	endothelium	endothelium	NN
cord-312486-rumqopg0	200	4	is	be	VBZ
cord-312486-rumqopg0	200	5	indispensable	indispensable	JJ
cord-312486-rumqopg0	200	6	for	for	IN
cord-312486-rumqopg0	200	7	the	the	DT
cord-312486-rumqopg0	200	8	regulation	regulation	NN
cord-312486-rumqopg0	200	9	of	of	IN
cord-312486-rumqopg0	200	10	vascular	vascular	JJ
cord-312486-rumqopg0	200	11	tone	tone	NN
cord-312486-rumqopg0	200	12	and	and	CC
cord-312486-rumqopg0	200	13	the	the	DT
cord-312486-rumqopg0	200	14	maintenance	maintenance	NN
cord-312486-rumqopg0	200	15	of	of	IN
cord-312486-rumqopg0	200	16	vascular	vascular	JJ
cord-312486-rumqopg0	200	17	homoeostasis	homoeostasis	NN
cord-312486-rumqopg0	200	18	.	.	.
cord-312486-rumqopg0	201	1	Endothelial	endothelial	JJ
cord-312486-rumqopg0	201	2	dysfunction	dysfunction	NN
cord-312486-rumqopg0	201	3	is	be	VBZ
cord-312486-rumqopg0	201	4	a	a	DT
cord-312486-rumqopg0	201	5	principal	principal	JJ
cord-312486-rumqopg0	201	6	determinant	determinant	NN
cord-312486-rumqopg0	201	7	of	of	IN
cord-312486-rumqopg0	201	8	microvascular	microvascular	JJ
cord-312486-rumqopg0	201	9	dysfunction	dysfunction	NN
cord-312486-rumqopg0	201	10	by	by	IN
cord-312486-rumqopg0	201	11	shifting	shift	VBG
cord-312486-rumqopg0	201	12	the	the	DT
cord-312486-rumqopg0	201	13	vascular	vascular	JJ
cord-312486-rumqopg0	201	14	equilibrium	equilibrium	NN
cord-312486-rumqopg0	201	15	towards	towards	IN
cord-312486-rumqopg0	201	16	more	more	JJR
cord-312486-rumqopg0	201	17	vasoconstriction	vasoconstriction	NN
cord-312486-rumqopg0	201	18	with	with	IN
cord-312486-rumqopg0	201	19	subsequent	subsequent	JJ
cord-312486-rumqopg0	201	20	organ	organ	NN
cord-312486-rumqopg0	201	21	ischemia	ischemia	NN
cord-312486-rumqopg0	201	22	,	,	,
cord-312486-rumqopg0	201	23	inflammation	inflammation	NN
cord-312486-rumqopg0	201	24	with	with	IN
cord-312486-rumqopg0	201	25	associated	associate	VBN
cord-312486-rumqopg0	201	26	tissue	tissue	NN
cord-312486-rumqopg0	201	27	edema	edema	NN
cord-312486-rumqopg0	201	28	,	,	,
cord-312486-rumqopg0	201	29	and	and	CC
cord-312486-rumqopg0	201	30	a	a	DT
cord-312486-rumqopg0	201	31	pro	pro	JJ
cord-312486-rumqopg0	201	32	-	-	JJ
cord-312486-rumqopg0	201	33	coagulant	coagulant	JJ
cord-312486-rumqopg0	201	34	state	state	NN
cord-312486-rumqopg0	201	35	[	[	-LRB-
cord-312486-rumqopg0	201	36	99	99	CD
cord-312486-rumqopg0	201	37	]	]	-RRB-
cord-312486-rumqopg0	201	38	.	.	.
cord-312486-rumqopg0	202	1	Vascular	vascular	JJ
cord-312486-rumqopg0	202	2	endothelial	endothelial	JJ
cord-312486-rumqopg0	202	3	damage	damage	NN
cord-312486-rumqopg0	202	4	could	could	MD
cord-312486-rumqopg0	202	5	explain	explain	VB
cord-312486-rumqopg0	202	6	why	why	WRB
cord-312486-rumqopg0	202	7	people	people	NNS
cord-312486-rumqopg0	202	8	with	with	IN
cord-312486-rumqopg0	202	9	pre	pre	JJ
cord-312486-rumqopg0	202	10	-	-	JJ
cord-312486-rumqopg0	202	11	existing	existing	JJ
cord-312486-rumqopg0	202	12	conditions	condition	NNS
cord-312486-rumqopg0	202	13	like	like	IN
cord-312486-rumqopg0	202	14	hypertension	hypertension	NN
cord-312486-rumqopg0	202	15	,	,	,
cord-312486-rumqopg0	202	16	diabetes	diabetes	NN
cord-312486-rumqopg0	202	17	,	,	,
cord-312486-rumqopg0	202	18	obesity	obesity	NN
cord-312486-rumqopg0	202	19	,	,	,
cord-312486-rumqopg0	202	20	and	and	CC
cord-312486-rumqopg0	202	21	cardiovascular	cardiovascular	JJ
cord-312486-rumqopg0	202	22	disease	disease	NN
cord-312486-rumqopg0	202	23	are	be	VBP
cord-312486-rumqopg0	202	24	at	at	IN
cord-312486-rumqopg0	202	25	a	a	DT
cord-312486-rumqopg0	202	26	higher	high	JJR
cord-312486-rumqopg0	202	27	risk	risk	NN
cord-312486-rumqopg0	202	28	for	for	IN
cord-312486-rumqopg0	202	29	severe	severe	JJ
cord-312486-rumqopg0	202	30	complications	complication	NNS
cord-312486-rumqopg0	202	31	.	.	.
cord-312486-rumqopg0	203	1	All	all	DT
cord-312486-rumqopg0	203	2	of	of	IN
cord-312486-rumqopg0	203	3	those	those	DT
cord-312486-rumqopg0	203	4	conditions	condition	NNS
cord-312486-rumqopg0	203	5	,	,	,
cord-312486-rumqopg0	203	6	identified	identify	VBN
cord-312486-rumqopg0	203	7	as	as	IN
cord-312486-rumqopg0	203	8	independent	independent	JJ
cord-312486-rumqopg0	203	9	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	203	10	risk	risk	NN
cord-312486-rumqopg0	203	11	factors	factor	NNS
cord-312486-rumqopg0	203	12	,	,	,
cord-312486-rumqopg0	203	13	cause	cause	VBP
cord-312486-rumqopg0	203	14	endothelial	endothelial	JJ
cord-312486-rumqopg0	203	15	cell	cell	NN
cord-312486-rumqopg0	203	16	dysfunction	dysfunction	NN
cord-312486-rumqopg0	203	17	.	.	.
cord-312486-rumqopg0	204	1	The	the	DT
cord-312486-rumqopg0	204	2	additional	additional	JJ
cord-312486-rumqopg0	204	3	damage	damage	NN
cord-312486-rumqopg0	204	4	and	and	CC
cord-312486-rumqopg0	204	5	inflammation	inflammation	NN
cord-312486-rumqopg0	204	6	in	in	IN
cord-312486-rumqopg0	204	7	the	the	DT
cord-312486-rumqopg0	204	8	blood	blood	NN
cord-312486-rumqopg0	204	9	vessels	vessel	NNS
cord-312486-rumqopg0	204	10	caused	cause	VBN
cord-312486-rumqopg0	204	11	by	by	IN
cord-312486-rumqopg0	204	12	the	the	DT
cord-312486-rumqopg0	204	13	viral	viral	JJ
cord-312486-rumqopg0	204	14	infection	infection	NN
cord-312486-rumqopg0	204	15	could	could	MD
cord-312486-rumqopg0	204	16	push	push	VB
cord-312486-rumqopg0	204	17	them	-PRON-	PRP
cord-312486-rumqopg0	204	18	over	over	IN
cord-312486-rumqopg0	204	19	the	the	DT
cord-312486-rumqopg0	204	20	edge	edge	NN
cord-312486-rumqopg0	204	21	and	and	CC
cord-312486-rumqopg0	204	22	cause	cause	VB
cord-312486-rumqopg0	204	23	catastrophic	catastrophic	JJ
cord-312486-rumqopg0	204	24	complications	complication	NNS
cord-312486-rumqopg0	204	25	[	[	-LRB-
cord-312486-rumqopg0	204	26	79	79	CD
cord-312486-rumqopg0	204	27	]	]	-RRB-
cord-312486-rumqopg0	204	28	.	.	.
cord-312486-rumqopg0	205	1	Given	give	VBN
cord-312486-rumqopg0	205	2	that	that	DT
cord-312486-rumqopg0	205	3	vascular	vascular	JJ
cord-312486-rumqopg0	205	4	endothelial	endothelial	JJ
cord-312486-rumqopg0	205	5	cells	cell	NNS
cord-312486-rumqopg0	205	6	express	express	VBP
cord-312486-rumqopg0	205	7	ACE2	ACE2	NNP
cord-312486-rumqopg0	205	8	,	,	,
cord-312486-rumqopg0	205	9	one	one	CD
cord-312486-rumqopg0	205	10	likely	likely	JJ
cord-312486-rumqopg0	205	11	hypothesis	hypothesis	NN
cord-312486-rumqopg0	205	12	suggests	suggest	VBZ
cord-312486-rumqopg0	205	13	that	that	IN
cord-312486-rumqopg0	205	14	SARS	SARS	NNP
cord-312486-rumqopg0	205	15	-	-	HYPH
cord-312486-rumqopg0	205	16	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	205	17	infects	infect	VBZ
cord-312486-rumqopg0	205	18	endothelial	endothelial	JJ
cord-312486-rumqopg0	205	19	cells	cell	NNS
cord-312486-rumqopg0	205	20	directly	directly	RB
cord-312486-rumqopg0	205	21	which	which	WDT
cord-312486-rumqopg0	205	22	induces	induce	VBZ
cord-312486-rumqopg0	205	23	injury	injury	NN
cord-312486-rumqopg0	205	24	,	,	,
cord-312486-rumqopg0	205	25	activates	activate	VBZ
cord-312486-rumqopg0	205	26	complement	complement	NN
cord-312486-rumqopg0	205	27	,	,	,
cord-312486-rumqopg0	205	28	and	and	CC
cord-312486-rumqopg0	205	29	sets	set	VBZ
cord-312486-rumqopg0	205	30	up	up	RP
cord-312486-rumqopg0	205	31	a	a	DT
cord-312486-rumqopg0	205	32	perpetual	perpetual	JJ
cord-312486-rumqopg0	205	33	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	205	34	state	state	NN
cord-312486-rumqopg0	205	35	[	[	-LRB-
cord-312486-rumqopg0	205	36	91	91	CD
cord-312486-rumqopg0	205	37	]	]	-RRB-
cord-312486-rumqopg0	205	38	.	.	.
cord-312486-rumqopg0	206	1	However	however	RB
cord-312486-rumqopg0	206	2	,	,	,
cord-312486-rumqopg0	206	3	there	there	EX
cord-312486-rumqopg0	206	4	are	be	VBP
cord-312486-rumqopg0	206	5	alternative	alternative	JJ
cord-312486-rumqopg0	206	6	mechanisms	mechanism	NNS
cord-312486-rumqopg0	206	7	for	for	IN
cord-312486-rumqopg0	206	8	activation	activation	NN
cord-312486-rumqopg0	206	9	of	of	IN
cord-312486-rumqopg0	206	10	endothelial	endothelial	JJ
cord-312486-rumqopg0	206	11	cells	cell	NNS
cord-312486-rumqopg0	206	12	and	and	CC
cord-312486-rumqopg0	206	13	vasculitis	vasculitis	NN
cord-312486-rumqopg0	206	14	induction	induction	NN
cord-312486-rumqopg0	206	15	that	that	WDT
cord-312486-rumqopg0	206	16	do	do	VBP
cord-312486-rumqopg0	206	17	not	not	RB
cord-312486-rumqopg0	206	18	necessarily	necessarily	RB
cord-312486-rumqopg0	206	19	require	require	VB
cord-312486-rumqopg0	206	20	the	the	DT
cord-312486-rumqopg0	206	21	presence	presence	NN
cord-312486-rumqopg0	206	22	of	of	IN
cord-312486-rumqopg0	206	23	the	the	DT
cord-312486-rumqopg0	206	24	virus	virus	NN
cord-312486-rumqopg0	206	25	itself	-PRON-	PRP
cord-312486-rumqopg0	206	26	,	,	,
cord-312486-rumqopg0	206	27	e.g.	e.g.	RB
cord-312486-rumqopg0	206	28	neutrophil	neutrophil	NN
cord-312486-rumqopg0	206	29	extracellular	extracellular	JJ
cord-312486-rumqopg0	206	30	traps	trap	NNS
cord-312486-rumqopg0	206	31	(	(	-LRB-
cord-312486-rumqopg0	206	32	NETs	nets	NN
cord-312486-rumqopg0	206	33	)	)	-RRB-
cord-312486-rumqopg0	206	34	[	[	-LRB-
cord-312486-rumqopg0	206	35	100	100	CD
cord-312486-rumqopg0	206	36	]	]	-RRB-
cord-312486-rumqopg0	206	37	and	and	CC
cord-312486-rumqopg0	206	38	hypoxia	hypoxia	NN
cord-312486-rumqopg0	206	39	[	[	-LRB-
cord-312486-rumqopg0	206	40	101	101	CD
cord-312486-rumqopg0	206	41	]	]	-RRB-
cord-312486-rumqopg0	206	42	.	.	.
cord-312486-rumqopg0	207	1	The	the	DT
cord-312486-rumqopg0	207	2	ability	ability	NN
cord-312486-rumqopg0	207	3	of	of	IN
cord-312486-rumqopg0	207	4	neutrophils	neutrophil	NNS
cord-312486-rumqopg0	207	5	to	to	TO
cord-312486-rumqopg0	207	6	form	form	VB
cord-312486-rumqopg0	207	7	NETs	NETs	NNP
cord-312486-rumqopg0	207	8	is	be	VBZ
cord-312486-rumqopg0	207	9	considered	consider	VBN
cord-312486-rumqopg0	207	10	beneficial	beneficial	JJ
cord-312486-rumqopg0	207	11	in	in	IN
cord-312486-rumqopg0	207	12	host	host	NN
cord-312486-rumqopg0	207	13	defense	defense	NN
cord-312486-rumqopg0	207	14	against	against	IN
cord-312486-rumqopg0	207	15	pathogens	pathogen	NNS
cord-312486-rumqopg0	207	16	,	,	,
cord-312486-rumqopg0	207	17	but	but	CC
cord-312486-rumqopg0	207	18	as	as	IN
cord-312486-rumqopg0	207	19	observed	observe	VBN
cord-312486-rumqopg0	207	20	regarding	regard	VBG
cord-312486-rumqopg0	207	21	other	other	JJ
cord-312486-rumqopg0	207	22	innate	innate	JJ
cord-312486-rumqopg0	207	23	immune	immune	JJ
cord-312486-rumqopg0	207	24	mechanisms	mechanism	NNS
cord-312486-rumqopg0	207	25	,	,	,
cord-312486-rumqopg0	207	26	sustained	sustain	VBD
cord-312486-rumqopg0	207	27	NET	net	JJ
cord-312486-rumqopg0	207	28	formation	formation	NN
cord-312486-rumqopg0	207	29	can	can	MD
cord-312486-rumqopg0	207	30	trigger	trigger	VB
cord-312486-rumqopg0	207	31	a	a	DT
cord-312486-rumqopg0	207	32	cascade	cascade	NN
cord-312486-rumqopg0	207	33	of	of	IN
cord-312486-rumqopg0	207	34	damaging	damaging	JJ
cord-312486-rumqopg0	207	35	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	207	36	reaction	reaction	NN
cord-312486-rumqopg0	207	37	.	.	.
cord-312486-rumqopg0	208	1	Indeed	indeed	RB
cord-312486-rumqopg0	208	2	elevated	elevated	JJ
cord-312486-rumqopg0	208	3	levels	level	NNS
cord-312486-rumqopg0	208	4	of	of	IN
cord-312486-rumqopg0	208	5	NET	net	NN
cord-312486-rumqopg0	208	6	-	-	HYPH
cord-312486-rumqopg0	208	7	specific	specific	JJ
cord-312486-rumqopg0	208	8	markers	marker	NNS
cord-312486-rumqopg0	208	9	,	,	,
cord-312486-rumqopg0	208	10	myeloperoxidase	myeloperoxidase	NN
cord-312486-rumqopg0	208	11	DNA	DNA	NNP
cord-312486-rumqopg0	208	12	,	,	,
cord-312486-rumqopg0	208	13	and	and	CC
cord-312486-rumqopg0	208	14	citrullinated	citrullinate	VBD
cord-312486-rumqopg0	208	15	histone	histone	NN
cord-312486-rumqopg0	208	16	H3	H3	NNP
cord-312486-rumqopg0	208	17	,	,	,
cord-312486-rumqopg0	208	18	were	be	VBD
cord-312486-rumqopg0	208	19	observed	observe	VBN
cord-312486-rumqopg0	208	20	in	in	IN
cord-312486-rumqopg0	208	21	the	the	DT
cord-312486-rumqopg0	208	22	sera	sera	NNP
cord-312486-rumqopg0	208	23	of	of	IN
cord-312486-rumqopg0	208	24	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	208	25	patients	patient	NNS
cord-312486-rumqopg0	208	26	[	[	-LRB-
cord-312486-rumqopg0	208	27	102	102	CD
cord-312486-rumqopg0	208	28	]	]	-RRB-
cord-312486-rumqopg0	208	29	.	.	.
cord-312486-rumqopg0	209	1	As	as	IN
cord-312486-rumqopg0	209	2	such	such	JJ
cord-312486-rumqopg0	209	3	,	,	,
cord-312486-rumqopg0	209	4	several	several	JJ
cord-312486-rumqopg0	209	5	research	research	NN
cord-312486-rumqopg0	209	6	groups	group	NNS
cord-312486-rumqopg0	209	7	are	be	VBP
cord-312486-rumqopg0	209	8	supporting	support	VBG
cord-312486-rumqopg0	209	9	a	a	DT
cord-312486-rumqopg0	209	10	more	more	RBR
cord-312486-rumqopg0	209	11	central	central	JJ
cord-312486-rumqopg0	209	12	role	role	NN
cord-312486-rumqopg0	209	13	for	for	IN
cord-312486-rumqopg0	209	14	NETs	net	NNS
cord-312486-rumqopg0	209	15	in	in	IN
cord-312486-rumqopg0	209	16	COVID-19	covid-19	JJ
cord-312486-rumqopg0	209	17	pathogenesis	pathogenesis	NN
cord-312486-rumqopg0	209	18	[	[	-LRB-
cord-312486-rumqopg0	209	19	102	102	CD
cord-312486-rumqopg0	209	20	,	,	,
cord-312486-rumqopg0	209	21	103	103	CD
cord-312486-rumqopg0	209	22	]	]	-RRB-
cord-312486-rumqopg0	209	23	.	.	.
cord-312486-rumqopg0	210	1	Coagulation	coagulation	NN
cord-312486-rumqopg0	210	2	disorders	disorder	NNS
cord-312486-rumqopg0	210	3	in	in	IN
cord-312486-rumqopg0	210	4	patients	patient	NNS
cord-312486-rumqopg0	210	5	with	with	IN
cord-312486-rumqopg0	210	6	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	210	7	were	be	VBD
cord-312486-rumqopg0	210	8	initially	initially	RB
cord-312486-rumqopg0	210	9	thought	think	VBN
cord-312486-rumqopg0	210	10	to	to	TO
cord-312486-rumqopg0	210	11	be	be	VB
cord-312486-rumqopg0	210	12	due	due	JJ
cord-312486-rumqopg0	210	13	to	to	IN
cord-312486-rumqopg0	210	14	systemic	systemic	JJ
cord-312486-rumqopg0	210	15	disseminated	disseminate	VBN
cord-312486-rumqopg0	210	16	intravascular	intravascular	JJ
cord-312486-rumqopg0	210	17	coagulopathy	coagulopathy	NN
cord-312486-rumqopg0	210	18	(	(	-LRB-
cord-312486-rumqopg0	210	19	DIC	DIC	NNP
cord-312486-rumqopg0	210	20	)	)	-RRB-
cord-312486-rumqopg0	210	21	.	.	.
cord-312486-rumqopg0	211	1	However	however	RB
cord-312486-rumqopg0	211	2	,	,	,
cord-312486-rumqopg0	211	3	considerable	considerable	JJ
cord-312486-rumqopg0	211	4	cross	cross	NN
cord-312486-rumqopg0	211	5	-	-	JJ
cord-312486-rumqopg0	211	6	talk	talk	JJ
cord-312486-rumqopg0	211	7	and	and	CC
cord-312486-rumqopg0	211	8	mutual	mutual	JJ
cord-312486-rumqopg0	211	9	engagement	engagement	NN
cord-312486-rumqopg0	211	10	between	between	IN
cord-312486-rumqopg0	211	11	the	the	DT
cord-312486-rumqopg0	211	12	complement	complement	NN
cord-312486-rumqopg0	211	13	and	and	CC
cord-312486-rumqopg0	211	14	the	the	DT
cord-312486-rumqopg0	211	15	coagulation	coagulation	NN
cord-312486-rumqopg0	211	16	cascades	cascade	NNS
cord-312486-rumqopg0	211	17	is	be	VBZ
cord-312486-rumqopg0	211	18	being	be	VBG
cord-312486-rumqopg0	211	19	increasingly	increasingly	RB
cord-312486-rumqopg0	211	20	documented	document	VBN
cord-312486-rumqopg0	211	21	in	in	IN
cord-312486-rumqopg0	211	22	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	211	23	and	and	CC
cord-312486-rumqopg0	211	24	seems	seem	VBZ
cord-312486-rumqopg0	211	25	to	to	TO
cord-312486-rumqopg0	211	26	be	be	VB
cord-312486-rumqopg0	211	27	responsible	responsible	JJ
cord-312486-rumqopg0	211	28	for	for	IN
cord-312486-rumqopg0	211	29	a	a	DT
cord-312486-rumqopg0	211	30	prothrombotic	prothrombotic	JJ
cord-312486-rumqopg0	211	31	environment	environment	NN
cord-312486-rumqopg0	211	32	distinct	distinct	JJ
cord-312486-rumqopg0	211	33	from	from	IN
cord-312486-rumqopg0	211	34	DIC	DIC	NNP
cord-312486-rumqopg0	211	35	,	,	,
cord-312486-rumqopg0	211	36	leading	lead	VBG
cord-312486-rumqopg0	211	37	to	to	IN
cord-312486-rumqopg0	211	38	serious	serious	JJ
cord-312486-rumqopg0	211	39	adverse	adverse	JJ
cord-312486-rumqopg0	211	40	outcomes	outcome	NNS
cord-312486-rumqopg0	211	41	[	[	-LRB-
cord-312486-rumqopg0	211	42	91	91	CD
cord-312486-rumqopg0	211	43	,	,	,
cord-312486-rumqopg0	211	44	104	104	CD
cord-312486-rumqopg0	211	45	]	]	-RRB-
cord-312486-rumqopg0	211	46	.	.	.
cord-312486-rumqopg0	212	1	In	in	IN
cord-312486-rumqopg0	212	2	fact	fact	NN
cord-312486-rumqopg0	212	3	,	,	,
cord-312486-rumqopg0	212	4	elevated	elevated	JJ
cord-312486-rumqopg0	212	5	D	d	NN
cord-312486-rumqopg0	212	6	-	-	HYPH
cord-312486-rumqopg0	212	7	dimer	dimer	NN
cord-312486-rumqopg0	212	8	(	(	-LRB-
cord-312486-rumqopg0	212	9	a	a	DT
cord-312486-rumqopg0	212	10	fibrin	fibrin	NN
cord-312486-rumqopg0	212	11	degradation	degradation	NN
cord-312486-rumqopg0	212	12	product	product	NN
cord-312486-rumqopg0	212	13	indicative	indicative	JJ
cord-312486-rumqopg0	212	14	of	of	IN
cord-312486-rumqopg0	212	15	hyperactive	hyperactive	JJ
cord-312486-rumqopg0	212	16	coagulation	coagulation	NN
cord-312486-rumqopg0	212	17	)	)	-RRB-
cord-312486-rumqopg0	212	18	has	have	VBZ
cord-312486-rumqopg0	212	19	emerged	emerge	VBN
cord-312486-rumqopg0	212	20	as	as	IN
cord-312486-rumqopg0	212	21	a	a	DT
cord-312486-rumqopg0	212	22	reliable	reliable	JJ
cord-312486-rumqopg0	212	23	marker	marker	NN
cord-312486-rumqopg0	212	24	of	of	IN
cord-312486-rumqopg0	212	25	severe	severe	JJ
cord-312486-rumqopg0	212	26	COVID-19	covid-19	JJ
cord-312486-rumqopg0	212	27	[	[	-LRB-
cord-312486-rumqopg0	212	28	105	105	CD
cord-312486-rumqopg0	212	29	,	,	,
cord-312486-rumqopg0	212	30	106	106	CD
cord-312486-rumqopg0	212	31	]	]	-RRB-
cord-312486-rumqopg0	212	32	.	.	.
cord-312486-rumqopg0	213	1	Interestingly	interestingly	RB
cord-312486-rumqopg0	213	2	,	,	,
cord-312486-rumqopg0	213	3	the	the	DT
cord-312486-rumqopg0	213	4	interconnected	interconnect	VBN
cord-312486-rumqopg0	213	5	complement	complement	NN
cord-312486-rumqopg0	213	6	and	and	CC
cord-312486-rumqopg0	213	7	coagulation	coagulation	NN
cord-312486-rumqopg0	213	8	cascades	cascade	NNS
cord-312486-rumqopg0	213	9	,	,	,
cord-312486-rumqopg0	213	10	which	which	WDT
cord-312486-rumqopg0	213	11	are	be	VBP
cord-312486-rumqopg0	213	12	being	be	VBG
cord-312486-rumqopg0	213	13	increasingly	increasingly	RB
cord-312486-rumqopg0	213	14	documented	document	VBN
cord-312486-rumqopg0	213	15	in	in	IN
cord-312486-rumqopg0	213	16	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	213	17	,	,	,
cord-312486-rumqopg0	213	18	has	have	VBZ
cord-312486-rumqopg0	213	19	been	be	VBN
cord-312486-rumqopg0	213	20	long	long	RB
cord-312486-rumqopg0	213	21	recognized	recognize	VBN
cord-312486-rumqopg0	213	22	in	in	IN
cord-312486-rumqopg0	213	23	antiphospholipid	antiphospholipid	NNP
cord-312486-rumqopg0	213	24	syndrome	syndrome	NN
cord-312486-rumqopg0	213	25	(	(	-LRB-
cord-312486-rumqopg0	213	26	APS	APS	NNP
cord-312486-rumqopg0	213	27	)	)	-RRB-
cord-312486-rumqopg0	213	28	[	[	-LRB-
cord-312486-rumqopg0	213	29	107	107	CD
cord-312486-rumqopg0	213	30	]	]	-RRB-
cord-312486-rumqopg0	213	31	.	.	.
cord-312486-rumqopg0	214	1	Given	give	VBN
cord-312486-rumqopg0	214	2	that	that	IN
cord-312486-rumqopg0	214	3	several	several	JJ
cord-312486-rumqopg0	214	4	publications	publication	NNS
cord-312486-rumqopg0	214	5	report	report	VBP
cord-312486-rumqopg0	214	6	antiphospholipid	antiphospholipid	NNP
cord-312486-rumqopg0	214	7	antibodies	antibody	NNS
cord-312486-rumqopg0	214	8	in	in	IN
cord-312486-rumqopg0	214	9	patients	patient	NNS
cord-312486-rumqopg0	214	10	with	with	IN
cord-312486-rumqopg0	214	11	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	214	12	[	[	-LRB-
cord-312486-rumqopg0	214	13	108	108	CD
cord-312486-rumqopg0	214	14	]	]	-RRB-
cord-312486-rumqopg0	214	15	[	[	-LRB-
cord-312486-rumqopg0	214	16	109	109	CD
cord-312486-rumqopg0	214	17	]	]	-RRB-
cord-312486-rumqopg0	214	18	[	[	-LRB-
cord-312486-rumqopg0	214	19	110	110	CD
cord-312486-rumqopg0	214	20	]	]	-RRB-
cord-312486-rumqopg0	214	21	,	,	,
cord-312486-rumqopg0	214	22	despite	despite	IN
cord-312486-rumqopg0	214	23	them	-PRON-	PRP
cord-312486-rumqopg0	214	24	not	not	RB
cord-312486-rumqopg0	214	25	fulfilling	fulfil	VBG
cord-312486-rumqopg0	214	26	the	the	DT
cord-312486-rumqopg0	214	27	Sydney	Sydney	NNP
cord-312486-rumqopg0	214	28	criteria	criterion	NNS
cord-312486-rumqopg0	214	29	for	for	IN
cord-312486-rumqopg0	214	30	APS	APS	NNP
cord-312486-rumqopg0	214	31	[	[	-LRB-
cord-312486-rumqopg0	214	32	111	111	CD
cord-312486-rumqopg0	214	33	]	]	-RRB-
cord-312486-rumqopg0	214	34	,	,	,
cord-312486-rumqopg0	214	35	it	-PRON-	PRP
cord-312486-rumqopg0	214	36	is	be	VBZ
cord-312486-rumqopg0	214	37	difficult	difficult	JJ
cord-312486-rumqopg0	214	38	to	to	TO
cord-312486-rumqopg0	214	39	ignore	ignore	VB
cord-312486-rumqopg0	214	40	how	how	WRB
cord-312486-rumqopg0	214	41	much	much	JJ
cord-312486-rumqopg0	214	42	the	the	DT
cord-312486-rumqopg0	214	43	clinical	clinical	JJ
cord-312486-rumqopg0	214	44	and	and	CC
cord-312486-rumqopg0	214	45	immunopathological	immunopathological	JJ
cord-312486-rumqopg0	214	46	picture	picture	NN
cord-312486-rumqopg0	214	47	of	of	IN
cord-312486-rumqopg0	214	48	APS	APS	NNP
cord-312486-rumqopg0	214	49	resembles	resemble	VBZ
cord-312486-rumqopg0	214	50	that	that	DT
cord-312486-rumqopg0	214	51	of	of	IN
cord-312486-rumqopg0	214	52	the	the	DT
cord-312486-rumqopg0	214	53	autopsy	autopsy	JJ
cord-312486-rumqopg0	214	54	findings	finding	NNS
cord-312486-rumqopg0	214	55	of	of	IN
cord-312486-rumqopg0	214	56	an	an	DT
cord-312486-rumqopg0	214	57	exaggerated	exaggerated	JJ
cord-312486-rumqopg0	214	58	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	214	59	state	state	NN
cord-312486-rumqopg0	214	60	and	and	CC
cord-312486-rumqopg0	214	61	thrombosis	thrombosis	NN
cord-312486-rumqopg0	214	62	in	in	IN
cord-312486-rumqopg0	214	63	many	many	JJ
cord-312486-rumqopg0	214	64	COVID-19	covid-19	JJ
cord-312486-rumqopg0	214	65	patients	patient	NNS
cord-312486-rumqopg0	214	66	[	[	-LRB-
cord-312486-rumqopg0	214	67	112	112	CD
cord-312486-rumqopg0	214	68	,	,	,
cord-312486-rumqopg0	214	69	113	113	CD
cord-312486-rumqopg0	214	70	]	]	-RRB-
cord-312486-rumqopg0	214	71	.	.	.
cord-312486-rumqopg0	215	1	A	a	DT
cord-312486-rumqopg0	215	2	study	study	NN
cord-312486-rumqopg0	215	3	by	by	IN
cord-312486-rumqopg0	215	4	Nicolai	Nicolai	NNP
cord-312486-rumqopg0	215	5	et	et	NNP
cord-312486-rumqopg0	215	6	al	al	NNP
cord-312486-rumqopg0	215	7	.	.	NNP
cord-312486-rumqopg0	215	8	,	,	,
cord-312486-rumqopg0	215	9	provides	provide	VBZ
cord-312486-rumqopg0	215	10	mechanistic	mechanistic	JJ
cord-312486-rumqopg0	215	11	evidence	evidence	NN
cord-312486-rumqopg0	215	12	that	that	IN
cord-312486-rumqopg0	215	13	multisystem	multisystem	JJ
cord-312486-rumqopg0	215	14	disease	disease	NN
cord-312486-rumqopg0	215	15	in	in	IN
cord-312486-rumqopg0	215	16	severe	severe	JJ
cord-312486-rumqopg0	215	17	COVID-19	covid-19	NN
cord-312486-rumqopg0	215	18	involves	involve	VBZ
cord-312486-rumqopg0	215	19	coagulopathy	coagulopathy	NN
cord-312486-rumqopg0	215	20	driven	drive	VBN
cord-312486-rumqopg0	215	21	by	by	IN
cord-312486-rumqopg0	215	22	dysregulated	dysregulate	VBN
cord-312486-rumqopg0	215	23	innate	innate	JJ
cord-312486-rumqopg0	215	24	immune	immune	JJ
cord-312486-rumqopg0	215	25	response	response	NN
cord-312486-rumqopg0	215	26	[	[	-LRB-
cord-312486-rumqopg0	215	27	114	114	CD
cord-312486-rumqopg0	215	28	]	]	-RRB-
cord-312486-rumqopg0	215	29	.	.	.
cord-312486-rumqopg0	216	1	They	-PRON-	PRP
cord-312486-rumqopg0	216	2	show	show	VBP
cord-312486-rumqopg0	216	3	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	216	4	microvascular	microvascular	JJ
cord-312486-rumqopg0	216	5	thrombi	thrombi	NN
cord-312486-rumqopg0	216	6	containing	contain	VBG
cord-312486-rumqopg0	216	7	platelets	platelet	NNS
cord-312486-rumqopg0	216	8	,	,	,
cord-312486-rumqopg0	216	9	fibrin	fibrin	NN
cord-312486-rumqopg0	216	10	,	,	,
cord-312486-rumqopg0	216	11	and	and	CC
cord-312486-rumqopg0	216	12	a	a	DT
cord-312486-rumqopg0	216	13	large	large	JJ
cord-312486-rumqopg0	216	14	number	number	NN
cord-312486-rumqopg0	216	15	of	of	IN
cord-312486-rumqopg0	216	16	neutrophils	neutrophil	NNS
cord-312486-rumqopg0	216	17	in	in	IN
cord-312486-rumqopg0	216	18	the	the	DT
cord-312486-rumqopg0	216	19	lung	lung	NN
cord-312486-rumqopg0	216	20	,	,	,
cord-312486-rumqopg0	216	21	kidney	kidney	NN
cord-312486-rumqopg0	216	22	and	and	CC
cord-312486-rumqopg0	216	23	heart	heart	NN
cord-312486-rumqopg0	216	24	.	.	.
cord-312486-rumqopg0	217	1	Neutrophils	neutrophil	NNS
cord-312486-rumqopg0	217	2	were	be	VBD
cord-312486-rumqopg0	217	3	highly	highly	RB
cord-312486-rumqopg0	217	4	activated	activate	VBN
cord-312486-rumqopg0	217	5	in	in	IN
cord-312486-rumqopg0	217	6	severe	severe	JJ
cord-312486-rumqopg0	217	7	cases	case	NNS
cord-312486-rumqopg0	217	8	compared	compare	VBN
cord-312486-rumqopg0	217	9	to	to	IN
cord-312486-rumqopg0	217	10	less	less	RBR
cord-312486-rumqopg0	217	11	severe	severe	JJ
cord-312486-rumqopg0	217	12	cases	case	NNS
cord-312486-rumqopg0	217	13	and	and	CC
cord-312486-rumqopg0	217	14	platelets	platelet	NNS
cord-312486-rumqopg0	217	15	showed	show	VBD
cord-312486-rumqopg0	217	16	enhanced	enhanced	JJ
cord-312486-rumqopg0	217	17	neutrophil	neutrophil	NN
cord-312486-rumqopg0	217	18	adhesion	adhesion	NN
cord-312486-rumqopg0	217	19	and	and	CC
cord-312486-rumqopg0	217	20	NET	net	NN
cord-312486-rumqopg0	217	21	formation	formation	NN
cord-312486-rumqopg0	217	22	in	in	IN
cord-312486-rumqopg0	217	23	multiple	multiple	JJ
cord-312486-rumqopg0	217	24	organs	organ	NNS
cord-312486-rumqopg0	217	25	.	.	.
cord-312486-rumqopg0	218	1	Thus	thus	RB
cord-312486-rumqopg0	218	2	,	,	,
cord-312486-rumqopg0	218	3	dysregulated	dysregulate	VBN
cord-312486-rumqopg0	218	4	immunothrombosis	immunothrombosis	NN
cord-312486-rumqopg0	218	5	is	be	VBZ
cord-312486-rumqopg0	218	6	linked	link	VBN
cord-312486-rumqopg0	218	7	to	to	IN
cord-312486-rumqopg0	218	8	both	both	DT
cord-312486-rumqopg0	218	9	ARDS	ARDS	NNP
cord-312486-rumqopg0	218	10	and	and	CC
cord-312486-rumqopg0	218	11	systemic	systemic	JJ
cord-312486-rumqopg0	218	12	hypercoagulability	hypercoagulability	NN
cord-312486-rumqopg0	218	13	[	[	-LRB-
cord-312486-rumqopg0	218	14	114	114	CD
cord-312486-rumqopg0	218	15	]	]	-RRB-
cord-312486-rumqopg0	218	16	.	.	.
cord-312486-rumqopg0	219	1	In	in	IN
cord-312486-rumqopg0	219	2	sum	sum	NN
cord-312486-rumqopg0	219	3	,	,	,
cord-312486-rumqopg0	219	4	an	an	DT
cord-312486-rumqopg0	219	5	overwhelmed	overwhelmed	JJ
cord-312486-rumqopg0	219	6	innate	innate	JJ
cord-312486-rumqopg0	219	7	immune	immune	JJ
cord-312486-rumqopg0	219	8	system	system	NN
cord-312486-rumqopg0	219	9	is	be	VBZ
cord-312486-rumqopg0	219	10	seemingly	seemingly	RB
cord-312486-rumqopg0	219	11	unable	unable	JJ
cord-312486-rumqopg0	219	12	to	to	TO
cord-312486-rumqopg0	219	13	assemble	assemble	VB
cord-312486-rumqopg0	219	14	a	a	DT
cord-312486-rumqopg0	219	15	balanced	balanced	JJ
cord-312486-rumqopg0	219	16	response	response	NN
cord-312486-rumqopg0	219	17	of	of	IN
cord-312486-rumqopg0	219	18	appropriate	appropriate	JJ
cord-312486-rumqopg0	219	19	cells	cell	NNS
cord-312486-rumqopg0	219	20	,	,	,
cord-312486-rumqopg0	219	21	cytokines	cytokine	NNS
cord-312486-rumqopg0	219	22	and	and	CC
cord-312486-rumqopg0	219	23	other	other	JJ
cord-312486-rumqopg0	219	24	molecules	molecule	NNS
cord-312486-rumqopg0	219	25	to	to	TO
cord-312486-rumqopg0	219	26	control	control	VB
cord-312486-rumqopg0	219	27	the	the	DT
cord-312486-rumqopg0	219	28	infection	infection	NN
cord-312486-rumqopg0	219	29	in	in	IN
cord-312486-rumqopg0	219	30	a	a	DT
cord-312486-rumqopg0	219	31	timely	timely	JJ
cord-312486-rumqopg0	219	32	fashion	fashion	NN
cord-312486-rumqopg0	219	33	.	.	.
cord-312486-rumqopg0	220	1	Instead	instead	RB
cord-312486-rumqopg0	220	2	,	,	,
cord-312486-rumqopg0	220	3	a	a	DT
cord-312486-rumqopg0	220	4	disoriented	disoriented	JJ
cord-312486-rumqopg0	220	5	,	,	,
cord-312486-rumqopg0	220	6	misguided	misguided	JJ
cord-312486-rumqopg0	220	7	storm	storm	NN
cord-312486-rumqopg0	220	8	of	of	IN
cord-312486-rumqopg0	220	9	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	220	10	cytokines	cytokine	NNS
cord-312486-rumqopg0	220	11	ends	end	VBZ
cord-312486-rumqopg0	220	12	up	up	RP
cord-312486-rumqopg0	220	13	destroying	destroy	VBG
cord-312486-rumqopg0	220	14	that	that	WDT
cord-312486-rumqopg0	220	15	which	which	WDT
cord-312486-rumqopg0	220	16	it	-PRON-	PRP
cord-312486-rumqopg0	220	17	intended	intend	VBD
cord-312486-rumqopg0	220	18	to	to	TO
cord-312486-rumqopg0	220	19	protect	protect	VB
cord-312486-rumqopg0	220	20	.	.	.
cord-312486-rumqopg0	221	1	It	-PRON-	PRP
cord-312486-rumqopg0	221	2	disintegrated	disintegrate	VBD
cord-312486-rumqopg0	221	3	in	in	IN
cord-312486-rumqopg0	221	4	moderate	moderate	JJ
cord-312486-rumqopg0	221	5	and	and	CC
cord-312486-rumqopg0	221	6	severe	severe	JJ
cord-312486-rumqopg0	221	7	COVID-19-lymphopenia	covid-19-lymphopenia	NN
cord-312486-rumqopg0	221	8	with	with	IN
cord-312486-rumqopg0	221	9	drastically	drastically	RB
cord-312486-rumqopg0	221	10	reduced	reduce	VBN
cord-312486-rumqopg0	221	11	CD4	CD4	NNP
cord-312486-rumqopg0	221	12	+	+	CC
cord-312486-rumqopg0	221	13	and	and	CC
cord-312486-rumqopg0	221	14	CD8	CD8	NNP
cord-312486-rumqopg0	221	15	+	+	CC
cord-312486-rumqopg0	221	16	T	T	NNP
cord-312486-rumqopg0	221	17	-	-	HYPH
cord-312486-rumqopg0	221	18	cells	cell	NNS
cord-312486-rumqopg0	221	19	is	be	VBZ
cord-312486-rumqopg0	221	20	the	the	DT
cord-312486-rumqopg0	221	21	most	most	RBS
cord-312486-rumqopg0	221	22	consistent	consistent	JJ
cord-312486-rumqopg0	221	23	finding	finding	NN
cord-312486-rumqopg0	221	24	in	in	IN
cord-312486-rumqopg0	221	25	moderate	moderate	JJ
cord-312486-rumqopg0	221	26	and	and	CC
cord-312486-rumqopg0	221	27	severe	severe	JJ
cord-312486-rumqopg0	221	28	COVID-19	covid-19	JJ
cord-312486-rumqopg0	221	29	patients	patient	NNS
cord-312486-rumqopg0	221	30	,	,	,
cord-312486-rumqopg0	221	31	which	which	WDT
cord-312486-rumqopg0	221	32	also	also	RB
cord-312486-rumqopg0	221	33	correlates	correlate	VBZ
cord-312486-rumqopg0	221	34	with	with	IN
cord-312486-rumqopg0	221	35	disease	disease	NN
cord-312486-rumqopg0	221	36	severity	severity	NN
cord-312486-rumqopg0	221	37	and	and	CC
cord-312486-rumqopg0	221	38	mortality	mortality	NN
cord-312486-rumqopg0	221	39	[	[	-LRB-
cord-312486-rumqopg0	221	40	115	115	CD
cord-312486-rumqopg0	221	41	]	]	-RRB-
cord-312486-rumqopg0	221	42	[	[	-LRB-
cord-312486-rumqopg0	221	43	116	116	CD
cord-312486-rumqopg0	221	44	]	]	-RRB-
cord-312486-rumqopg0	221	45	[	[	-LRB-
cord-312486-rumqopg0	221	46	117	117	CD
cord-312486-rumqopg0	221	47	]	]	-RRB-
cord-312486-rumqopg0	221	48	[	[	-LRB-
cord-312486-rumqopg0	221	49	118	118	CD
cord-312486-rumqopg0	221	50	]	]	-RRB-
cord-312486-rumqopg0	221	51	.	.	.
cord-312486-rumqopg0	222	1	B	b	NN
cord-312486-rumqopg0	222	2	-	-	HYPH
cord-312486-rumqopg0	222	3	cells	cell	NNS
cord-312486-rumqopg0	222	4	are	be	VBP
cord-312486-rumqopg0	222	5	decreased	decrease	VBN
cord-312486-rumqopg0	222	6	as	as	RB
cord-312486-rumqopg0	222	7	well	well	RB
cord-312486-rumqopg0	222	8	[	[	-LRB-
cord-312486-rumqopg0	222	9	119	119	CD
cord-312486-rumqopg0	222	10	,	,	,
cord-312486-rumqopg0	222	11	120	120	CD
cord-312486-rumqopg0	222	12	]	]	-RRB-
cord-312486-rumqopg0	222	13	 	 	_SP
cord-312486-rumqopg0	222	14	unlikely	unlikely	JJ
cord-312486-rumqopg0	222	15	to	to	TO
cord-312486-rumqopg0	222	16	be	be	VB
cord-312486-rumqopg0	222	17	the	the	DT
cord-312486-rumqopg0	222	18	case	case	NN
cord-312486-rumqopg0	222	19	[	[	-LRB-
cord-312486-rumqopg0	222	20	88	88	CD
cord-312486-rumqopg0	222	21	]	]	-RRB-
cord-312486-rumqopg0	222	22	.	.	.
cord-312486-rumqopg0	223	1	Despite	despite	IN
cord-312486-rumqopg0	223	2	the	the	DT
cord-312486-rumqopg0	223	3	fact	fact	NN
cord-312486-rumqopg0	223	4	that	that	IN
cord-312486-rumqopg0	223	5	lymphopenia	lymphopenia	NNP
cord-312486-rumqopg0	223	6	seems	seem	VBZ
cord-312486-rumqopg0	223	7	to	to	TO
cord-312486-rumqopg0	223	8	be	be	VB
cord-312486-rumqopg0	223	9	a	a	DT
cord-312486-rumqopg0	223	10	prominent	prominent	JJ
cord-312486-rumqopg0	223	11	feature	feature	NN
cord-312486-rumqopg0	223	12	of	of	IN
cord-312486-rumqopg0	223	13	severe	severe	JJ
cord-312486-rumqopg0	223	14	COVID-19	covid-19	NN
cord-312486-rumqopg0	223	15	,	,	,
cord-312486-rumqopg0	223	16	patients	patient	NNS
cord-312486-rumqopg0	223	17	under	under	IN
cord-312486-rumqopg0	223	18	immunosuppressive	immunosuppressive	JJ
cord-312486-rumqopg0	223	19	therapy	therapy	NN
cord-312486-rumqopg0	223	20	are	be	VBP
cord-312486-rumqopg0	223	21	not	not	RB
cord-312486-rumqopg0	223	22	at	at	IN
cord-312486-rumqopg0	223	23	a	a	DT
cord-312486-rumqopg0	223	24	higher	high	JJR
cord-312486-rumqopg0	223	25	risk	risk	NN
cord-312486-rumqopg0	223	26	for	for	IN
cord-312486-rumqopg0	223	27	infection	infection	NN
cord-312486-rumqopg0	223	28	,	,	,
cord-312486-rumqopg0	223	29	and	and	CC
cord-312486-rumqopg0	223	30	if	if	IN
cord-312486-rumqopg0	223	31	infected	infect	VBN
cord-312486-rumqopg0	223	32	seem	seem	VBP
cord-312486-rumqopg0	223	33	not	not	RB
cord-312486-rumqopg0	223	34	to	to	TO
cord-312486-rumqopg0	223	35	be	be	VB
cord-312486-rumqopg0	223	36	destined	destine	VBN
cord-312486-rumqopg0	223	37	to	to	TO
cord-312486-rumqopg0	223	38	have	have	VB
cord-312486-rumqopg0	223	39	more	more	JJR
cord-312486-rumqopg0	223	40	severe	severe	JJ
cord-312486-rumqopg0	223	41	progression	progression	NN
cord-312486-rumqopg0	223	42	.	.	.
cord-312486-rumqopg0	224	1	In	in	IN
cord-312486-rumqopg0	224	2	fact	fact	NN
cord-312486-rumqopg0	224	3	,	,	,
cord-312486-rumqopg0	224	4	reviewing	review	VBG
cord-312486-rumqopg0	224	5	the	the	DT
cord-312486-rumqopg0	224	6	mortality	mortality	NN
cord-312486-rumqopg0	224	7	and	and	CC
cord-312486-rumqopg0	224	8	morbidity	morbidity	NN
cord-312486-rumqopg0	224	9	reports	report	NNS
cord-312486-rumqopg0	224	10	published	publish	VBN
cord-312486-rumqopg0	224	11	on	on	IN
cord-312486-rumqopg0	224	12	SARS	SARS	NNP
cord-312486-rumqopg0	224	13	-	-	HYPH
cord-312486-rumqopg0	224	14	CoV-1	CoV-1	NNP
cord-312486-rumqopg0	224	15	,	,	,
cord-312486-rumqopg0	224	16	MERS	MERS	NNP
cord-312486-rumqopg0	224	17	-	-	HYPH
cord-312486-rumqopg0	224	18	CoV	CoV	NNP
cord-312486-rumqopg0	224	19	,	,	,
cord-312486-rumqopg0	224	20	and	and	CC
cord-312486-rumqopg0	224	21	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	224	22	,	,	,
cord-312486-rumqopg0	224	23	no	no	DT
cord-312486-rumqopg0	224	24	mention	mention	NN
cord-312486-rumqopg0	224	25	is	be	VBZ
cord-312486-rumqopg0	224	26	made	make	VBN
cord-312486-rumqopg0	224	27	on	on	IN
cord-312486-rumqopg0	224	28	immunosuppression	immunosuppression	NN
cord-312486-rumqopg0	224	29	as	as	IN
cord-312486-rumqopg0	224	30	a	a	DT
cord-312486-rumqopg0	224	31	risk	risk	NN
cord-312486-rumqopg0	224	32	factor	factor	NN
cord-312486-rumqopg0	224	33	for	for	IN
cord-312486-rumqopg0	224	34	morbidity	morbidity	NN
cord-312486-rumqopg0	224	35	and	and	CC
cord-312486-rumqopg0	224	36	mortality	mortality	NN
cord-312486-rumqopg0	224	37	.	.	.
cord-312486-rumqopg0	225	1	Further	further	RB
cord-312486-rumqopg0	225	2	,	,	,
cord-312486-rumqopg0	225	3	no	no	DT
cord-312486-rumqopg0	225	4	severe	severe	JJ
cord-312486-rumqopg0	225	5	complications	complication	NNS
cord-312486-rumqopg0	225	6	or	or	CC
cord-312486-rumqopg0	225	7	fatality	fatality	NN
cord-312486-rumqopg0	225	8	is	be	VBZ
cord-312486-rumqopg0	225	9	reported	report	VBN
cord-312486-rumqopg0	225	10	to	to	TO
cord-312486-rumqopg0	225	11	be	be	VB
cord-312486-rumqopg0	225	12	linked	link	VBN
cord-312486-rumqopg0	225	13	to	to	IN
cord-312486-rumqopg0	225	14	transplantation	transplantation	NN
cord-312486-rumqopg0	225	15	,	,	,
cord-312486-rumqopg0	225	16	chemotherapy	chemotherapy	NN
cord-312486-rumqopg0	225	17	,	,	,
cord-312486-rumqopg0	225	18	autoimmune	autoimmune	JJ
cord-312486-rumqopg0	225	19	hepatitis	hepatitis	NN
cord-312486-rumqopg0	225	20	,	,	,
cord-312486-rumqopg0	225	21	IBD	IBD	NNP
cord-312486-rumqopg0	225	22	,	,	,
cord-312486-rumqopg0	225	23	or	or	CC
cord-312486-rumqopg0	225	24	other	other	JJ
cord-312486-rumqopg0	225	25	conditions	condition	NNS
cord-312486-rumqopg0	225	26	requiring	require	VBG
cord-312486-rumqopg0	225	27	immuno	immuno	JJ
cord-312486-rumqopg0	225	28	-	-	HYPH
cord-312486-rumqopg0	225	29	suppressive	suppressive	JJ
cord-312486-rumqopg0	225	30	treatment	treatment	NN
cord-312486-rumqopg0	225	31	for	for	IN
cord-312486-rumqopg0	225	32	patients	patient	NNS
cord-312486-rumqopg0	225	33	at	at	IN
cord-312486-rumqopg0	225	34	any	any	DT
cord-312486-rumqopg0	225	35	age	age	NN
cord-312486-rumqopg0	225	36	[	[	-LRB-
cord-312486-rumqopg0	225	37	121	121	CD
cord-312486-rumqopg0	225	38	,	,	,
cord-312486-rumqopg0	225	39	122	122	CD
cord-312486-rumqopg0	225	40	]	]	-RRB-
cord-312486-rumqopg0	225	41	.	.	.
cord-312486-rumqopg0	226	1	In	in	IN
cord-312486-rumqopg0	226	2	fact	fact	NN
cord-312486-rumqopg0	226	3	,	,	,
cord-312486-rumqopg0	226	4	reviewing	review	VBG
cord-312486-rumqopg0	226	5	the	the	DT
cord-312486-rumqopg0	226	6	mortality	mortality	NN
cord-312486-rumqopg0	226	7	and	and	CC
cord-312486-rumqopg0	226	8	morbidity	morbidity	NN
cord-312486-rumqopg0	226	9	reports	report	NNS
cord-312486-rumqopg0	226	10	published	publish	VBN
cord-312486-rumqopg0	226	11	J	J	NNP
cord-312486-rumqopg0	226	12	o	o	NN
cord-312486-rumqopg0	226	13	u	u	NN
cord-312486-rumqopg0	226	14	r	r	NN
cord-312486-rumqopg0	226	15	n	n	NN
cord-312486-rumqopg0	226	16	a	a	DT
cord-312486-rumqopg0	226	17	l	l	NN
cord-312486-rumqopg0	226	18	P	p	NN
cord-312486-rumqopg0	226	19	r	r	NN
cord-312486-rumqopg0	226	20	e	e	NN
cord-312486-rumqopg0	226	21	-p	-p	NN
cord-312486-rumqopg0	227	1	r	r	NNP
cord-312486-rumqopg0	227	2	o	o	NN
cord-312486-rumqopg0	227	3	o	o	NN
cord-312486-rumqopg0	227	4	f	f	NN
cord-312486-rumqopg0	227	5	on	on	IN
cord-312486-rumqopg0	227	6	SARS	SARS	NNP
cord-312486-rumqopg0	227	7	-	-	HYPH
cord-312486-rumqopg0	227	8	CoV-1	CoV-1	NNP
cord-312486-rumqopg0	227	9	,	,	,
cord-312486-rumqopg0	227	10	MERS	MERS	NNP
cord-312486-rumqopg0	227	11	-	-	HYPH
cord-312486-rumqopg0	227	12	CoV	CoV	NNP
cord-312486-rumqopg0	227	13	,	,	,
cord-312486-rumqopg0	227	14	and	and	CC
cord-312486-rumqopg0	227	15	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	227	16	,	,	,
cord-312486-rumqopg0	227	17	no	no	DT
cord-312486-rumqopg0	227	18	mention	mention	NN
cord-312486-rumqopg0	227	19	is	be	VBZ
cord-312486-rumqopg0	227	20	made	make	VBN
cord-312486-rumqopg0	227	21	on	on	IN
cord-312486-rumqopg0	227	22	immunosuppression	immunosuppression	NN
cord-312486-rumqopg0	227	23	as	as	IN
cord-312486-rumqopg0	227	24	a	a	DT
cord-312486-rumqopg0	227	25	risk	risk	NN
cord-312486-rumqopg0	227	26	factor	factor	NN
cord-312486-rumqopg0	227	27	for	for	IN
cord-312486-rumqopg0	227	28	morbidity	morbidity	NN
cord-312486-rumqopg0	227	29	and	and	CC
cord-312486-rumqopg0	227	30	mortality	mortality	NN
cord-312486-rumqopg0	227	31	.	.	.
cord-312486-rumqopg0	228	1	Further	further	RB
cord-312486-rumqopg0	228	2	,	,	,
cord-312486-rumqopg0	228	3	no	no	DT
cord-312486-rumqopg0	228	4	severe	severe	JJ
cord-312486-rumqopg0	228	5	complications	complication	NNS
cord-312486-rumqopg0	228	6	or	or	CC
cord-312486-rumqopg0	228	7	fatality	fatality	NN
cord-312486-rumqopg0	228	8	is	be	VBZ
cord-312486-rumqopg0	228	9	reported	report	VBN
cord-312486-rumqopg0	228	10	to	to	TO
cord-312486-rumqopg0	228	11	be	be	VB
cord-312486-rumqopg0	228	12	linked	link	VBN
cord-312486-rumqopg0	228	13	to	to	IN
cord-312486-rumqopg0	228	14	transplantation	transplantation	NN
cord-312486-rumqopg0	228	15	,	,	,
cord-312486-rumqopg0	228	16	chemotherapy	chemotherapy	NN
cord-312486-rumqopg0	228	17	,	,	,
cord-312486-rumqopg0	228	18	autoimmune	autoimmune	JJ
cord-312486-rumqopg0	228	19	hepatitis	hepatitis	NN
cord-312486-rumqopg0	228	20	,	,	,
cord-312486-rumqopg0	228	21	IBD	IBD	NNP
cord-312486-rumqopg0	228	22	,	,	,
cord-312486-rumqopg0	228	23	or	or	CC
cord-312486-rumqopg0	228	24	other	other	JJ
cord-312486-rumqopg0	228	25	conditions	condition	NNS
cord-312486-rumqopg0	228	26	requiring	require	VBG
cord-312486-rumqopg0	228	27	immuno	immuno	JJ
cord-312486-rumqopg0	228	28	-	-	HYPH
cord-312486-rumqopg0	228	29	suppressive	suppressive	JJ
cord-312486-rumqopg0	228	30	treatment	treatment	NN
cord-312486-rumqopg0	228	31	for	for	IN
cord-312486-rumqopg0	228	32	patients	patient	NNS
cord-312486-rumqopg0	228	33	at	at	IN
cord-312486-rumqopg0	228	34	any	any	DT
cord-312486-rumqopg0	228	35	age	age	NN
cord-312486-rumqopg0	228	36	[	[	-LRB-
cord-312486-rumqopg0	228	37	121	121	CD
cord-312486-rumqopg0	228	38	,	,	,
cord-312486-rumqopg0	228	39	122	122	CD
cord-312486-rumqopg0	228	40	]	]	-RRB-
cord-312486-rumqopg0	228	41	.	.	.
cord-312486-rumqopg0	229	1	These	these	DT
cord-312486-rumqopg0	229	2	observations	observation	NNS
cord-312486-rumqopg0	229	3	reinforce	reinforce	VBP
cord-312486-rumqopg0	229	4	the	the	DT
cord-312486-rumqopg0	229	5	notion	notion	NN
cord-312486-rumqopg0	229	6	that	that	IN
cord-312486-rumqopg0	229	7	the	the	DT
cord-312486-rumqopg0	229	8	reduced	reduce	VBN
cord-312486-rumqopg0	229	9	T	t	NN
cord-312486-rumqopg0	229	10	and	and	CC
cord-312486-rumqopg0	229	11	B	b	NN
cord-312486-rumqopg0	229	12	lymphocytes	lymphocyte	NNS
cord-312486-rumqopg0	229	13	in	in	IN
cord-312486-rumqopg0	229	14	COVID-19	covid-19	JJ
cord-312486-rumqopg0	229	15	patients	patient	NNS
cord-312486-rumqopg0	229	16	is	be	VBZ
cord-312486-rumqopg0	229	17	not	not	RB
cord-312486-rumqopg0	229	18	the	the	DT
cord-312486-rumqopg0	229	19	direct	direct	JJ
cord-312486-rumqopg0	229	20	cytopathic	cytopathic	JJ
cord-312486-rumqopg0	229	21	effect	effect	NN
cord-312486-rumqopg0	229	22	of	of	IN
cord-312486-rumqopg0	229	23	the	the	DT
cord-312486-rumqopg0	229	24	virus	virus	NN
cord-312486-rumqopg0	229	25	itself	-PRON-	PRP
cord-312486-rumqopg0	229	26	.	.	.
cord-312486-rumqopg0	230	1	The	the	DT
cord-312486-rumqopg0	230	2	possibility	possibility	NN
cord-312486-rumqopg0	230	3	that	that	IN
cord-312486-rumqopg0	230	4	the	the	DT
cord-312486-rumqopg0	230	5	peripheral	peripheral	JJ
cord-312486-rumqopg0	230	6	lymphopenia	lymphopenia	NNP
cord-312486-rumqopg0	230	7	observed	observe	VBN
cord-312486-rumqopg0	230	8	in	in	IN
cord-312486-rumqopg0	230	9	patients	patient	NNS
cord-312486-rumqopg0	230	10	with	with	IN
cord-312486-rumqopg0	230	11	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	230	12	reflects	reflect	VBZ
cord-312486-rumqopg0	230	13	recruitment	recruitment	NN
cord-312486-rumqopg0	230	14	of	of	IN
cord-312486-rumqopg0	230	15	lymphocytes	lymphocyte	NNS
cord-312486-rumqopg0	230	16	to	to	IN
cord-312486-rumqopg0	230	17	the	the	DT
cord-312486-rumqopg0	230	18	respiratory	respiratory	JJ
cord-312486-rumqopg0	230	19	tract	tract	NN
cord-312486-rumqopg0	230	20	or	or	CC
cord-312486-rumqopg0	230	21	adhesion	adhesion	NN
cord-312486-rumqopg0	230	22	to	to	IN
cord-312486-rumqopg0	230	23	inflamed	inflamed	JJ
cord-312486-rumqopg0	230	24	respiratory	respiratory	JJ
cord-312486-rumqopg0	230	25	vascular	vascular	JJ
cord-312486-rumqopg0	230	26	endothelium	endothelium	NN
cord-312486-rumqopg0	230	27	has	have	VBZ
cord-312486-rumqopg0	230	28	been	be	VBN
cord-312486-rumqopg0	230	29	suggested	suggest	VBN
cord-312486-rumqopg0	230	30	[	[	-LRB-
cord-312486-rumqopg0	230	31	31	31	CD
cord-312486-rumqopg0	230	32	]	]	-RRB-
cord-312486-rumqopg0	230	33	.	.	.
cord-312486-rumqopg0	231	1	Although	although	IN
cord-312486-rumqopg0	231	2	autopsy	autopsy	JJ
cord-312486-rumqopg0	231	3	studies	study	NNS
cord-312486-rumqopg0	231	4	of	of	IN
cord-312486-rumqopg0	231	5	patients	patient	NNS
cord-312486-rumqopg0	231	6	'	'	POS
cord-312486-rumqopg0	231	7	lungs	lung	NNS
cord-312486-rumqopg0	231	8	and	and	CC
cord-312486-rumqopg0	231	9	single	single	JJ
cord-312486-rumqopg0	231	10	-	-	HYPH
cord-312486-rumqopg0	231	11	cell	cell	NN
cord-312486-rumqopg0	231	12	RNA	rna	NN
cord-312486-rumqopg0	231	13	sequencing	sequencing	NN
cord-312486-rumqopg0	231	14	of	of	IN
cord-312486-rumqopg0	231	15	BALF	BALF	NNP
cord-312486-rumqopg0	231	16	do	do	VBP
cord-312486-rumqopg0	231	17	identify	identify	VB
cord-312486-rumqopg0	231	18	the	the	DT
cord-312486-rumqopg0	231	19	presence	presence	NN
cord-312486-rumqopg0	231	20	of	of	IN
cord-312486-rumqopg0	231	21	lymphocytes	lymphocyte	NNS
cord-312486-rumqopg0	231	22	,	,	,
cord-312486-rumqopg0	231	23	the	the	DT
cord-312486-rumqopg0	231	24	lymphocytic	lymphocytic	JJ
cord-312486-rumqopg0	231	25	infiltration	infiltration	NN
cord-312486-rumqopg0	231	26	is	be	VBZ
cord-312486-rumqopg0	231	27	modest	modest	JJ
cord-312486-rumqopg0	231	28	at	at	IN
cord-312486-rumqopg0	231	29	best	well	RBS
cord-312486-rumqopg0	231	30	,	,	,
cord-312486-rumqopg0	231	31	arguing	argue	VBG
cord-312486-rumqopg0	231	32	against	against	IN
cord-312486-rumqopg0	231	33	sequestration	sequestration	NN
cord-312486-rumqopg0	231	34	as	as	IN
cord-312486-rumqopg0	231	35	a	a	DT
cord-312486-rumqopg0	231	36	main	main	JJ
cord-312486-rumqopg0	231	37	cause	cause	NN
cord-312486-rumqopg0	231	38	of	of	IN
cord-312486-rumqopg0	231	39	lymphopenia	lymphopenia	NNP
cord-312486-rumqopg0	231	40	[	[	-LRB-
cord-312486-rumqopg0	231	41	123	123	CD
cord-312486-rumqopg0	231	42	]	]	-RRB-
cord-312486-rumqopg0	231	43	.	.	.
cord-312486-rumqopg0	232	1	The	the	DT
cord-312486-rumqopg0	232	2	most	most	RBS
cord-312486-rumqopg0	232	3	likely	likely	JJ
cord-312486-rumqopg0	232	4	scenario	scenario	NN
cord-312486-rumqopg0	232	5	is	be	VBZ
cord-312486-rumqopg0	232	6	that	that	IN
cord-312486-rumqopg0	232	7	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	232	8	cytokines	cytokine	NNS
cord-312486-rumqopg0	232	9	are	be	VBP
cord-312486-rumqopg0	232	10	key	key	JJ
cord-312486-rumqopg0	232	11	factors	factor	NNS
cord-312486-rumqopg0	232	12	behind	behind	IN
cord-312486-rumqopg0	232	13	the	the	DT
cord-312486-rumqopg0	232	14	observed	observed	JJ
cord-312486-rumqopg0	232	15	lymphopenia	lymphopenia	NNP
cord-312486-rumqopg0	232	16	.	.	.
cord-312486-rumqopg0	233	1	Indeed	indeed	RB
cord-312486-rumqopg0	233	2	,	,	,
cord-312486-rumqopg0	233	3	serum	serum	NN
cord-312486-rumqopg0	233	4	levels	level	NNS
cord-312486-rumqopg0	233	5	of	of	IN
cord-312486-rumqopg0	233	6	IL-6	IL-6	NNP
cord-312486-rumqopg0	233	7	especially	especially	RB
cord-312486-rumqopg0	233	8	have	have	VBP
cord-312486-rumqopg0	233	9	been	be	VBN
cord-312486-rumqopg0	233	10	closely	closely	RB
cord-312486-rumqopg0	233	11	correlated	correlate	VBN
cord-312486-rumqopg0	233	12	with	with	IN
cord-312486-rumqopg0	233	13	lymphopenia	lymphopenia	NNP
cord-312486-rumqopg0	233	14	,	,	,
cord-312486-rumqopg0	233	15	while	while	IN
cord-312486-rumqopg0	233	16	recovered	recover	VBN
cord-312486-rumqopg0	233	17	patients	patient	NNS
cord-312486-rumqopg0	233	18	show	show	VBP
cord-312486-rumqopg0	233	19	return	return	NN
cord-312486-rumqopg0	233	20	of	of	IN
cord-312486-rumqopg0	233	21	lymphocytes	lymphocyte	NNS
cord-312486-rumqopg0	233	22	numbers	number	NNS
cord-312486-rumqopg0	233	23	towards	towards	IN
cord-312486-rumqopg0	233	24	the	the	DT
cord-312486-rumqopg0	233	25	normal	normal	JJ
cord-312486-rumqopg0	233	26	range	range	NN
cord-312486-rumqopg0	233	27	with	with	IN
cord-312486-rumqopg0	233	28	significant	significant	JJ
cord-312486-rumqopg0	233	29	reduction	reduction	NN
cord-312486-rumqopg0	233	30	in	in	IN
cord-312486-rumqopg0	233	31	IL-6	IL-6	NNP
cord-312486-rumqopg0	233	32	levels	level	NNS
cord-312486-rumqopg0	233	33	.	.	.
cord-312486-rumqopg0	234	1	A	a	DT
cord-312486-rumqopg0	234	2	likely	likely	JJ
cord-312486-rumqopg0	234	3	mechanism	mechanism	NN
cord-312486-rumqopg0	234	4	is	be	VBZ
cord-312486-rumqopg0	234	5	via	via	IN
cord-312486-rumqopg0	234	6	the	the	DT
cord-312486-rumqopg0	234	7	downregulation	downregulation	NN
cord-312486-rumqopg0	234	8	of	of	IN
cord-312486-rumqopg0	234	9	multiple	multiple	JJ
cord-312486-rumqopg0	234	10	HLA	HLA	NNP
cord-312486-rumqopg0	234	11	class	class	NN
cord-312486-rumqopg0	234	12	II	II	NNP
cord-312486-rumqopg0	234	13	molecules	molecule	NNS
cord-312486-rumqopg0	234	14	on	on	IN
cord-312486-rumqopg0	234	15	CD14	CD14	NNP
cord-312486-rumqopg0	234	16	monocytes	monocyte	NNS
cord-312486-rumqopg0	234	17	and	and	CC
cord-312486-rumqopg0	234	18	B	b	NN
cord-312486-rumqopg0	234	19	-	-	HYPH
cord-312486-rumqopg0	234	20	cells	cell	NNS
cord-312486-rumqopg0	234	21	by	by	IN
cord-312486-rumqopg0	234	22	IL-6	IL-6	NNP
cord-312486-rumqopg0	234	23	,	,	,
cord-312486-rumqopg0	234	24	as	as	IN
cord-312486-rumqopg0	234	25	demonstrated	demonstrate	VBN
cord-312486-rumqopg0	234	26	by	by	IN
cord-312486-rumqopg0	234	27	multiple	multiple	JJ
cord-312486-rumqopg0	234	28	studies	study	NNS
cord-312486-rumqopg0	234	29	[	[	-LRB-
cord-312486-rumqopg0	234	30	82	82	CD
cord-312486-rumqopg0	234	31	,	,	,
cord-312486-rumqopg0	234	32	119	119	CD
cord-312486-rumqopg0	234	33	,	,	,
cord-312486-rumqopg0	234	34	120	120	CD
cord-312486-rumqopg0	234	35	]	]	-RRB-
cord-312486-rumqopg0	234	36	.	.	.
cord-312486-rumqopg0	235	1	HLA	HLA	NNP
cord-312486-rumqopg0	235	2	class	class	NN
cord-312486-rumqopg0	236	1	I	-PRON-	PRP
cord-312486-rumqopg0	236	2	molecule	molecule	VBP
cord-312486-rumqopg0	237	1	downregulation	downregulation	NN
cord-312486-rumqopg0	237	2	was	be	VBD
cord-312486-rumqopg0	237	3	less	less	RBR
cord-312486-rumqopg0	237	4	severe	severe	JJ
cord-312486-rumqopg0	237	5	and	and	CC
cord-312486-rumqopg0	237	6	inconsistently	inconsistently	RB
cord-312486-rumqopg0	237	7	observed	observe	VBD
cord-312486-rumqopg0	237	8	.	.	.
cord-312486-rumqopg0	238	1	A	a	DT
cord-312486-rumqopg0	238	2	negative	negative	JJ
cord-312486-rumqopg0	238	3	correlation	correlation	NN
cord-312486-rumqopg0	238	4	between	between	IN
cord-312486-rumqopg0	238	5	serum	serum	NN
cord-312486-rumqopg0	238	6	levels	level	NNS
cord-312486-rumqopg0	238	7	of	of	IN
cord-312486-rumqopg0	238	8	IL-6	IL-6	NNP
cord-312486-rumqopg0	238	9	and	and	CC
cord-312486-rumqopg0	238	10	the	the	DT
cord-312486-rumqopg0	238	11	number	number	NN
cord-312486-rumqopg0	238	12	of	of	IN
cord-312486-rumqopg0	238	13	class	class	NN
cord-312486-rumqopg0	238	14	II	II	NNP
cord-312486-rumqopg0	238	15	HLA	HLA	NNP
cord-312486-rumqopg0	238	16	on	on	IN
cord-312486-rumqopg0	238	17	CD14	CD14	NNP
cord-312486-rumqopg0	238	18	+	+	CC
cord-312486-rumqopg0	238	19	monocytes	monocyte	NNS
cord-312486-rumqopg0	238	20	supports	support	VBZ
cord-312486-rumqopg0	238	21	the	the	DT
cord-312486-rumqopg0	238	22	notion	notion	NN
cord-312486-rumqopg0	238	23	of	of	IN
cord-312486-rumqopg0	238	24	downregulation	downregulation	NN
cord-312486-rumqopg0	238	25	of	of	IN
cord-312486-rumqopg0	238	26	class	class	NN
cord-312486-rumqopg0	238	27	II	II	NNP
cord-312486-rumqopg0	238	28	by	by	IN
cord-312486-rumqopg0	238	29	IL-6	IL-6	NNP
cord-312486-rumqopg0	238	30	[	[	-LRB-
cord-312486-rumqopg0	238	31	82	82	CD
cord-312486-rumqopg0	238	32	,	,	,
cord-312486-rumqopg0	238	33	119	119	CD
cord-312486-rumqopg0	238	34	]	]	-RRB-
cord-312486-rumqopg0	238	35	.	.	.
cord-312486-rumqopg0	239	1	This	this	DT
cord-312486-rumqopg0	239	2	decrease	decrease	NN
cord-312486-rumqopg0	239	3	in	in	IN
cord-312486-rumqopg0	239	4	HLA	HLA	NNP
cord-312486-rumqopg0	239	5	molecules	molecule	NNS
cord-312486-rumqopg0	239	6	suggests	suggest	VBZ
cord-312486-rumqopg0	239	7	that	that	IN
cord-312486-rumqopg0	239	8	severe	severe	JJ
cord-312486-rumqopg0	239	9	COVID-19	covid-19	JJ
cord-312486-rumqopg0	239	10	patients	patient	NNS
cord-312486-rumqopg0	239	11	might	may	MD
cord-312486-rumqopg0	239	12	be	be	VB
cord-312486-rumqopg0	239	13	unable	unable	JJ
cord-312486-rumqopg0	239	14	to	to	TO
cord-312486-rumqopg0	239	15	mount	mount	VB
cord-312486-rumqopg0	239	16	a	a	DT
cord-312486-rumqopg0	239	17	normal	normal	JJ
cord-312486-rumqopg0	239	18	T	T	NNP
cord-312486-rumqopg0	239	19	cell	cell	NN
cord-312486-rumqopg0	239	20	response	response	NN
cord-312486-rumqopg0	239	21	due	due	JJ
cord-312486-rumqopg0	239	22	to	to	IN
cord-312486-rumqopg0	239	23	reduced	reduce	VBN
cord-312486-rumqopg0	239	24	antigen	antigen	NN
cord-312486-rumqopg0	239	25	presentation	presentation	NN
cord-312486-rumqopg0	239	26	capability	capability	NN
cord-312486-rumqopg0	239	27	to	to	IN
cord-312486-rumqopg0	239	28	T	t	NN
cord-312486-rumqopg0	239	29	cell	cell	NN
cord-312486-rumqopg0	239	30	receptors	receptor	NNS
cord-312486-rumqopg0	239	31	(	(	-LRB-
cord-312486-rumqopg0	239	32	TCR	TCR	NNP
cord-312486-rumqopg0	239	33	)	)	-RRB-
cord-312486-rumqopg0	239	34	.	.	.
cord-312486-rumqopg0	240	1	Such	such	JJ
cord-312486-rumqopg0	240	2	T	t	NN
cord-312486-rumqopg0	240	3	cells	cell	NNS
cord-312486-rumqopg0	240	4	are	be	VBP
cord-312486-rumqopg0	240	5	then	then	RB
cord-312486-rumqopg0	240	6	eliminated	eliminate	VBN
cord-312486-rumqopg0	240	7	by	by	IN
cord-312486-rumqopg0	240	8	apoptosis	apoptosis	NN
cord-312486-rumqopg0	240	9	.	.	.
cord-312486-rumqopg0	241	1	Autopsy	autopsy	JJ
cord-312486-rumqopg0	241	2	studies	study	NNS
cord-312486-rumqopg0	241	3	on	on	IN
cord-312486-rumqopg0	241	4	lymphoid	lymphoid	JJ
cord-312486-rumqopg0	241	5	organs	organ	NNS
cord-312486-rumqopg0	241	6	collected	collect	VBN
cord-312486-rumqopg0	241	7	from	from	IN
cord-312486-rumqopg0	241	8	patients	patient	NNS
cord-312486-rumqopg0	241	9	who	who	WP
cord-312486-rumqopg0	241	10	succumbed	succumb	VBD
cord-312486-rumqopg0	241	11	to	to	IN
cord-312486-rumqopg0	241	12	the	the	DT
cord-312486-rumqopg0	241	13	disease	disease	NN
cord-312486-rumqopg0	241	14	revealed	reveal	VBD
cord-312486-rumqopg0	241	15	massive	massive	JJ
cord-312486-rumqopg0	241	16	lymphocyte	lymphocyte	NN
cord-312486-rumqopg0	241	17	death	death	NN
cord-312486-rumqopg0	241	18	,	,	,
cord-312486-rumqopg0	241	19	which	which	WDT
cord-312486-rumqopg0	241	20	was	be	VBD
cord-312486-rumqopg0	241	21	linked	link	VBN
cord-312486-rumqopg0	241	22	to	to	IN
cord-312486-rumqopg0	241	23	high	high	JJ
cord-312486-rumqopg0	241	24	levels	level	NNS
cord-312486-rumqopg0	241	25	of	of	IN
cord-312486-rumqopg0	241	26	IL-6	IL-6	NNP
cord-312486-rumqopg0	241	27	as	as	RB
cord-312486-rumqopg0	241	28	well	well	RB
cord-312486-rumqopg0	241	29	as	as	IN
cord-312486-rumqopg0	241	30	Fas	Fas	NNP
cord-312486-rumqopg0	241	31	-	-	HYPH
cord-312486-rumqopg0	241	32	induced	induce	VBN
cord-312486-rumqopg0	241	33	apoptosis	apoptosis	NN
cord-312486-rumqopg0	241	34	[	[	-LRB-
cord-312486-rumqopg0	241	35	124	124	CD
cord-312486-rumqopg0	241	36	]	]	-RRB-
cord-312486-rumqopg0	241	37	.	.	.
cord-312486-rumqopg0	242	1	Treatment	treatment	NN
cord-312486-rumqopg0	242	2	with	with	IN
cord-312486-rumqopg0	242	3	Tocilizumab	Tocilizumab	NNP
cord-312486-rumqopg0	242	4	,	,	,
cord-312486-rumqopg0	242	5	an	an	DT
cord-312486-rumqopg0	242	6	IL-6	IL-6	NNP
cord-312486-rumqopg0	242	7	receptor	receptor	NN
cord-312486-rumqopg0	242	8	antagonist	antagonist	NN
cord-312486-rumqopg0	242	9	,	,	,
cord-312486-rumqopg0	242	10	restores	restore	VBZ
cord-312486-rumqopg0	242	11	,	,	,
cord-312486-rumqopg0	242	12	at	at	IN
cord-312486-rumqopg0	242	13	least	least	JJS
cord-312486-rumqopg0	242	14	partially	partially	RB
cord-312486-rumqopg0	242	15	,	,	,
cord-312486-rumqopg0	242	16	the	the	DT
cord-312486-rumqopg0	242	17	HLA	HLA	NNP
cord-312486-rumqopg0	242	18	class	class	NN
cord-312486-rumqopg0	242	19	II	II	NNP
cord-312486-rumqopg0	242	20	molecules	molecule	NNS
cord-312486-rumqopg0	242	21	on	on	IN
cord-312486-rumqopg0	242	22	antigen	antigen	NN
cord-312486-rumqopg0	242	23	-	-	HYPH
cord-312486-rumqopg0	242	24	presenting	present	VBG
cord-312486-rumqopg0	242	25	cells	cell	NNS
cord-312486-rumqopg0	242	26	.	.	.
cord-312486-rumqopg0	243	1	In	in	IN
cord-312486-rumqopg0	243	2	addition	addition	NN
cord-312486-rumqopg0	243	3	,	,	,
cord-312486-rumqopg0	243	4	it	-PRON-	PRP
cord-312486-rumqopg0	243	5	increased	increase	VBD
cord-312486-rumqopg0	243	6	the	the	DT
cord-312486-rumqopg0	243	7	number	number	NN
cord-312486-rumqopg0	243	8	of	of	IN
cord-312486-rumqopg0	243	9	circulatory	circulatory	JJ
cord-312486-rumqopg0	243	10	lymphocytes	lymphocyte	NNS
cord-312486-rumqopg0	243	11	,	,	,
cord-312486-rumqopg0	243	12	further	further	RB
cord-312486-rumqopg0	243	13	suggesting	suggest	VBG
cord-312486-rumqopg0	243	14	IL-6	IL-6	NNP
cord-312486-rumqopg0	243	15	is	be	VBZ
cord-312486-rumqopg0	243	16	a	a	DT
cord-312486-rumqopg0	243	17	key	key	JJ
cord-312486-rumqopg0	243	18	player	player	NN
cord-312486-rumqopg0	243	19	in	in	IN
cord-312486-rumqopg0	243	20	the	the	DT
cord-312486-rumqopg0	243	21	lymphopenia	lymphopenia	NNP
cord-312486-rumqopg0	243	22	development	development	NN
cord-312486-rumqopg0	243	23	[	[	-LRB-
cord-312486-rumqopg0	243	24	119	119	CD
cord-312486-rumqopg0	243	25	]	]	-RRB-
cord-312486-rumqopg0	243	26	.	.	.
cord-312486-rumqopg0	244	1	Further	further	RB
cord-312486-rumqopg0	244	2	,	,	,
cord-312486-rumqopg0	244	3	NK	NK	NNP
cord-312486-rumqopg0	244	4	T	T	NNP
cord-312486-rumqopg0	244	5	-	-	HYPH
cord-312486-rumqopg0	244	6	cells	cell	NNS
cord-312486-rumqopg0	244	7	are	be	VBP
cord-312486-rumqopg0	244	8	reduced	reduce	VBN
cord-312486-rumqopg0	244	9	in	in	IN
cord-312486-rumqopg0	244	10	number	number	NN
cord-312486-rumqopg0	244	11	and	and	CC
cord-312486-rumqopg0	244	12	impaired	impair	VBN
cord-312486-rumqopg0	244	13	in	in	IN
cord-312486-rumqopg0	244	14	function	function	NN
cord-312486-rumqopg0	244	15	in	in	IN
cord-312486-rumqopg0	244	16	severe	severe	JJ
cord-312486-rumqopg0	244	17	COVID-19	covid-19	NN
cord-312486-rumqopg0	244	18	in	in	IN
cord-312486-rumqopg0	244	19	an	an	DT
cord-312486-rumqopg0	244	20	IL-6	IL-6	NNP
cord-312486-rumqopg0	244	21	dependent	dependent	JJ
cord-312486-rumqopg0	244	22	manner	manner	NN
cord-312486-rumqopg0	244	23	[	[	-LRB-
cord-312486-rumqopg0	244	24	120	120	CD
cord-312486-rumqopg0	244	25	]	]	-RRB-
cord-312486-rumqopg0	244	26	.	.	.
cord-312486-rumqopg0	245	1	Since	since	IN
cord-312486-rumqopg0	245	2	CD8	CD8	NNP
cord-312486-rumqopg0	245	3	+	+	CC
cord-312486-rumqopg0	245	4	T	T	NNP
cord-312486-rumqopg0	245	5	cells	cell	NNS
cord-312486-rumqopg0	245	6	require	require	VBP
cord-312486-rumqopg0	245	7	antigen	antigen	NN
cord-312486-rumqopg0	245	8	presentation	presentation	NN
cord-312486-rumqopg0	245	9	by	by	IN
cord-312486-rumqopg0	245	10	HLA	HLA	NNP
cord-312486-rumqopg0	245	11	class	class	NN
cord-312486-rumqopg0	245	12	I	-PRON-	PRP
cord-312486-rumqopg0	245	13	for	for	IN
cord-312486-rumqopg0	245	14	activation	activation	NN
cord-312486-rumqopg0	245	15	via	via	IN
cord-312486-rumqopg0	245	16	TCR	TCR	NNP
cord-312486-rumqopg0	245	17	,	,	,
cord-312486-rumqopg0	245	18	and	and	CC
cord-312486-rumqopg0	245	19	these	these	DT
cord-312486-rumqopg0	245	20	molecules	molecule	NNS
cord-312486-rumqopg0	245	21	are	be	VBP
cord-312486-rumqopg0	245	22	less	less	RBR
cord-312486-rumqopg0	245	23	reduced	reduce	VBN
cord-312486-rumqopg0	245	24	than	than	IN
cord-312486-rumqopg0	245	25	class	class	NN
cord-312486-rumqopg0	245	26	II	II	NNP
cord-312486-rumqopg0	245	27	molecule	molecule	NN
cord-312486-rumqopg0	245	28	,	,	,
cord-312486-rumqopg0	245	29	it	-PRON-	PRP
cord-312486-rumqopg0	245	30	is	be	VBZ
cord-312486-rumqopg0	245	31	unlikely	unlikely	JJ
cord-312486-rumqopg0	245	32	that	that	IN
cord-312486-rumqopg0	245	33	the	the	DT
cord-312486-rumqopg0	245	34	same	same	JJ
cord-312486-rumqopg0	245	35	mechanism	mechanism	NN
cord-312486-rumqopg0	245	36	of	of	IN
cord-312486-rumqopg0	245	37	apoptosis	apoptosis	NN
cord-312486-rumqopg0	245	38	of	of	IN
cord-312486-rumqopg0	245	39	inactivated	inactivate	VBN
cord-312486-rumqopg0	245	40	CD4	CD4	NNP
cord-312486-rumqopg0	245	41	+	+	CC
cord-312486-rumqopg0	245	42	T	t	NN
cord-312486-rumqopg0	245	43	cells	cell	NNS
cord-312486-rumqopg0	245	44	would	would	MD
cord-312486-rumqopg0	245	45	be	be	VB
cord-312486-rumqopg0	245	46	operating	operate	VBG
cord-312486-rumqopg0	245	47	to	to	IN
cord-312486-rumqopg0	245	48	a	a	DT
cord-312486-rumqopg0	245	49	similar	similar	JJ
cord-312486-rumqopg0	245	50	extent	extent	NN
cord-312486-rumqopg0	245	51	in	in	IN
cord-312486-rumqopg0	245	52	CD8	CD8	NNP
cord-312486-rumqopg0	245	53	+	+	CC
cord-312486-rumqopg0	245	54	T	T	NNP
cord-312486-rumqopg0	245	55	cells	cell	NNS
cord-312486-rumqopg0	245	56	.	.	.
cord-312486-rumqopg0	246	1	Rather	rather	RB
cord-312486-rumqopg0	246	2	,	,	,
cord-312486-rumqopg0	246	3	it	-PRON-	PRP
cord-312486-rumqopg0	246	4	is	be	VBZ
cord-312486-rumqopg0	246	5	possible	possible	JJ
cord-312486-rumqopg0	246	6	that	that	IN
cord-312486-rumqopg0	246	7	most	most	JJS
cord-312486-rumqopg0	246	8	CD8	CD8	NNS
cord-312486-rumqopg0	246	9	+	+	CC
cord-312486-rumqopg0	246	10	are	be	VBP
cord-312486-rumqopg0	246	11	eliminated	eliminate	VBN
cord-312486-rumqopg0	246	12	due	due	IN
cord-312486-rumqopg0	246	13	to	to	IN
cord-312486-rumqopg0	246	14	activation	activation	NN
cord-312486-rumqopg0	246	15	/	/	SYM
cord-312486-rumqopg0	246	16	exhaustion	exhaustion	NN
cord-312486-rumqopg0	246	17	of	of	IN
cord-312486-rumqopg0	246	18	T	t	NN
cord-312486-rumqopg0	246	19	cells	cell	NNS
cord-312486-rumqopg0	246	20	[	[	-LRB-
cord-312486-rumqopg0	246	21	116	116	CD
cord-312486-rumqopg0	246	22	]	]	-RRB-
cord-312486-rumqopg0	246	23	.	.	.
cord-312486-rumqopg0	247	1	Intense	intense	JJ
cord-312486-rumqopg0	247	2	immune	immune	JJ
cord-312486-rumqopg0	247	3	profiling	profiling	NN
cord-312486-rumqopg0	247	4	of	of	IN
cord-312486-rumqopg0	247	5	COVID-19	covid-19	CD
cord-312486-rumqopg0	247	6	patients	patient	NNS
cord-312486-rumqopg0	247	7	show	show	VBP
cord-312486-rumqopg0	247	8	a	a	DT
cord-312486-rumqopg0	247	9	very	very	RB
cord-312486-rumqopg0	247	10	heterogeneous	heterogeneous	JJ
cord-312486-rumqopg0	247	11	immune	immune	JJ
cord-312486-rumqopg0	247	12	response	response	NN
cord-312486-rumqopg0	247	13	.	.	.
cord-312486-rumqopg0	248	1	A	a	DT
cord-312486-rumqopg0	248	2	rigorous	rigorous	JJ
cord-312486-rumqopg0	248	3	comparison	comparison	NN
cord-312486-rumqopg0	248	4	between	between	IN
cord-312486-rumqopg0	248	5	the	the	DT
cord-312486-rumqopg0	248	6	studies	study	NNS
cord-312486-rumqopg0	248	7	is	be	VBZ
cord-312486-rumqopg0	248	8	complicated	complicate	VBN
cord-312486-rumqopg0	248	9	by	by	IN
cord-312486-rumqopg0	248	10	major	major	JJ
cord-312486-rumqopg0	248	11	differences	difference	NNS
cord-312486-rumqopg0	248	12	in	in	IN
cord-312486-rumqopg0	248	13	cohort	cohort	NN
cord-312486-rumqopg0	248	14	sizes	size	NNS
cord-312486-rumqopg0	248	15	,	,	,
cord-312486-rumqopg0	248	16	dissimilar	dissimilar	JJ
cord-312486-rumqopg0	248	17	clinical	clinical	JJ
cord-312486-rumqopg0	248	18	phenotypes	phenotype	NNS
cord-312486-rumqopg0	248	19	used	use	VBN
cord-312486-rumqopg0	248	20	,	,	,
cord-312486-rumqopg0	248	21	utilization	utilization	NN
cord-312486-rumqopg0	248	22	of	of	IN
cord-312486-rumqopg0	248	23	different	different	JJ
cord-312486-rumqopg0	248	24	experimental	experimental	JJ
cord-312486-rumqopg0	248	25	strategies	strategy	NNS
cord-312486-rumqopg0	248	26	,	,	,
cord-312486-rumqopg0	248	27	and	and	CC
cord-312486-rumqopg0	248	28	emphasis	emphasis	NN
cord-312486-rumqopg0	248	29	on	on	IN
cord-312486-rumqopg0	248	30	different	different	JJ
cord-312486-rumqopg0	248	31	parameters	parameter	NNS
cord-312486-rumqopg0	248	32	by	by	IN
cord-312486-rumqopg0	248	33	various	various	JJ
cord-312486-rumqopg0	248	34	investigators	investigator	NNS
cord-312486-rumqopg0	248	35	.	.	.
cord-312486-rumqopg0	249	1	The	the	DT
cord-312486-rumqopg0	249	2	study	study	NN
cord-312486-rumqopg0	249	3	by	by	IN
cord-312486-rumqopg0	249	4	Giamarellos	Giamarellos	NNP
cord-312486-rumqopg0	249	5	-	-	HYPH
cord-312486-rumqopg0	249	6	Bourboulis	Bourboulis	NNP
cord-312486-rumqopg0	249	7	et	et	NNP
cord-312486-rumqopg0	249	8	al	al	NNP
cord-312486-rumqopg0	249	9	.	.	.
cord-312486-rumqopg0	250	1	[	[	-LRB-
cord-312486-rumqopg0	250	2	119	119	CD
cord-312486-rumqopg0	250	3	]	]	-RRB-
cord-312486-rumqopg0	250	4	suggest	suggest	VBP
cord-312486-rumqopg0	250	5	that	that	IN
cord-312486-rumqopg0	250	6	severe	severe	JJ
cord-312486-rumqopg0	250	7	COVID-19	covid-19	JJ
cord-312486-rumqopg0	250	8	patients	patient	NNS
cord-312486-rumqopg0	250	9	developing	develop	VBG
cord-312486-rumqopg0	250	10	severe	severe	JJ
cord-312486-rumqopg0	250	11	respiratory	respiratory	JJ
cord-312486-rumqopg0	250	12	failure	failure	NN
cord-312486-rumqopg0	250	13	show	show	VBP
cord-312486-rumqopg0	250	14	one	one	CD
cord-312486-rumqopg0	250	15	of	of	IN
cord-312486-rumqopg0	250	16	two	two	CD
cord-312486-rumqopg0	250	17	immune	immune	JJ
cord-312486-rumqopg0	250	18	phenotypes	phenotype	NNS
cord-312486-rumqopg0	250	19	:	:	:
cord-312486-rumqopg0	250	20	(	(	-LRB-
cord-312486-rumqopg0	250	21	1	1	LS
cord-312486-rumqopg0	250	22	)	)	-RRB-
cord-312486-rumqopg0	250	23	an	an	DT
cord-312486-rumqopg0	250	24	immune	immune	JJ
cord-312486-rumqopg0	250	25	dysregulation	dysregulation	NN
cord-312486-rumqopg0	250	26	phenotype	phenotype	NN
cord-312486-rumqopg0	250	27	(	(	-LRB-
cord-312486-rumqopg0	250	28	~75	~75	CD
cord-312486-rumqopg0	250	29	%	%	NN
cord-312486-rumqopg0	250	30	of	of	IN
cord-312486-rumqopg0	250	31	patients	patient	NNS
cord-312486-rumqopg0	250	32	)	)	-RRB-
cord-312486-rumqopg0	250	33	characterized	characterize	VBN
cord-312486-rumqopg0	250	34	by	by	IN
cord-312486-rumqopg0	250	35	major	major	JJ
cord-312486-rumqopg0	250	36	reduction	reduction	NN
cord-312486-rumqopg0	250	37	of	of	IN
cord-312486-rumqopg0	250	38	HLA	HLA	NNP
cord-312486-rumqopg0	250	39	-	-	HYPH
cord-312486-rumqopg0	250	40	class	class	NN
cord-312486-rumqopg0	250	41	II	ii	CD
cord-312486-rumqopg0	250	42	molecules	molecule	NNS
cord-312486-rumqopg0	250	43	on	on	IN
cord-312486-rumqopg0	250	44	CD14	CD14	NNP
cord-312486-rumqopg0	250	45	+	+	CC
cord-312486-rumqopg0	250	46	monocytes	monocyte	NNS
cord-312486-rumqopg0	250	47	in	in	IN
cord-312486-rumqopg0	250	48	the	the	DT
cord-312486-rumqopg0	250	49	absence	absence	NN
cord-312486-rumqopg0	250	50	of	of	IN
cord-312486-rumqopg0	250	51	elevated	elevated	JJ
cord-312486-rumqopg0	250	52	ferritin	ferritin	NN
cord-312486-rumqopg0	250	53	.	.	.
cord-312486-rumqopg0	251	1	This	this	DT
cord-312486-rumqopg0	251	2	is	be	VBZ
cord-312486-rumqopg0	251	3	triggered	trigger	VBN
cord-312486-rumqopg0	251	4	by	by	IN
cord-312486-rumqopg0	251	5	monocyte	monocyte	NNP
cord-312486-rumqopg0	251	6	J	J	NNP
cord-312486-rumqopg0	251	7	o	o	NNP
cord-312486-rumqopg0	251	8	u	u	NN
cord-312486-rumqopg0	251	9	r	r	NNP
cord-312486-rumqopg0	251	10	n	n	NN
cord-312486-rumqopg0	251	11	a	a	DT
cord-312486-rumqopg0	251	12	l	l	NN
cord-312486-rumqopg0	251	13	P	p	NN
cord-312486-rumqopg0	251	14	r	r	NN
cord-312486-rumqopg0	251	15	e	e	NN
cord-312486-rumqopg0	252	1	-p	-p	:
cord-312486-rumqopg0	253	1	r	r	NNP
cord-312486-rumqopg0	253	2	o	o	NN
cord-312486-rumqopg0	253	3	o	o	NN
cord-312486-rumqopg0	253	4	f	f	NN
cord-312486-rumqopg0	253	5	hyperactivation	hyperactivation	NNP
cord-312486-rumqopg0	253	6	,	,	,
cord-312486-rumqopg0	253	7	excessive	excessive	JJ
cord-312486-rumqopg0	253	8	IL-6	IL-6	NNP
cord-312486-rumqopg0	253	9	production	production	NN
cord-312486-rumqopg0	253	10	,	,	,
cord-312486-rumqopg0	253	11	and	and	CC
cord-312486-rumqopg0	253	12	profound	profound	JJ
cord-312486-rumqopg0	253	13	lymphopenia	lymphopenia	NNP
cord-312486-rumqopg0	253	14	,	,	,
cord-312486-rumqopg0	253	15	but	but	CC
cord-312486-rumqopg0	253	16	without	without	IN
cord-312486-rumqopg0	253	17	IL-1β	il-1β	NN
cord-312486-rumqopg0	253	18	elevation	elevation	NN
cord-312486-rumqopg0	253	19	;	;	:
cord-312486-rumqopg0	253	20	and	and	CC
cord-312486-rumqopg0	253	21	(	(	-LRB-
cord-312486-rumqopg0	253	22	2	2	LS
cord-312486-rumqopg0	253	23	)	)	-RRB-
cord-312486-rumqopg0	253	24	a	a	DT
cord-312486-rumqopg0	253	25	MAS	MAS	NNP
cord-312486-rumqopg0	253	26	phenotype	phenotype	NN
cord-312486-rumqopg0	253	27	(	(	-LRB-
cord-312486-rumqopg0	253	28	~25	~25	CD
cord-312486-rumqopg0	253	29	%	%	NN
cord-312486-rumqopg0	253	30	)	)	-RRB-
cord-312486-rumqopg0	253	31	associated	associate	VBN
cord-312486-rumqopg0	253	32	with	with	IN
cord-312486-rumqopg0	253	33	elevated	elevated	JJ
cord-312486-rumqopg0	253	34	ferritin	ferritin	NN
cord-312486-rumqopg0	253	35	,	,	,
cord-312486-rumqopg0	253	36	with	with	IN
cord-312486-rumqopg0	253	37	relatively	relatively	RB
cord-312486-rumqopg0	253	38	less	less	JJR
cord-312486-rumqopg0	253	39	reduction	reduction	NN
cord-312486-rumqopg0	253	40	of	of	IN
cord-312486-rumqopg0	253	41	HLA	HLA	NNP
cord-312486-rumqopg0	253	42	class	class	NN
cord-312486-rumqopg0	253	43	II	II	NNP
cord-312486-rumqopg0	253	44	molecules	molecule	NNS
cord-312486-rumqopg0	253	45	on	on	IN
cord-312486-rumqopg0	253	46	monocytes	monocyte	NNS
cord-312486-rumqopg0	253	47	and	and	CC
cord-312486-rumqopg0	253	48	triggered	trigger	VBN
cord-312486-rumqopg0	253	49	by	by	IN
cord-312486-rumqopg0	253	50	IL-1β	il-1β	NN
cord-312486-rumqopg0	253	51	.	.	.
cord-312486-rumqopg0	254	1	Further	further	JJ
cord-312486-rumqopg0	254	2	studies	study	NNS
cord-312486-rumqopg0	254	3	will	will	MD
cord-312486-rumqopg0	254	4	be	be	VB
cord-312486-rumqopg0	254	5	needed	need	VBN
cord-312486-rumqopg0	254	6	to	to	TO
cord-312486-rumqopg0	254	7	verify	verify	VB
cord-312486-rumqopg0	254	8	whether	whether	IN
cord-312486-rumqopg0	254	9	these	these	DT
cord-312486-rumqopg0	254	10	immunophenotypes	immunophenotype	NNS
cord-312486-rumqopg0	254	11	are	be	VBP
cord-312486-rumqopg0	254	12	generalizable	generalizable	JJ
cord-312486-rumqopg0	254	13	.	.	.
cord-312486-rumqopg0	255	1	Mathew	Mathew	NNP
cord-312486-rumqopg0	255	2	et	et	NNP
cord-312486-rumqopg0	255	3	al	al	NNP
cord-312486-rumqopg0	255	4	.	.	.
cord-312486-rumqopg0	256	1	[	[	-LRB-
cord-312486-rumqopg0	256	2	125	125	CD
cord-312486-rumqopg0	256	3	]	]	-RRB-
cord-312486-rumqopg0	256	4	identified	identify	VBD
cord-312486-rumqopg0	256	5	a	a	DT
cord-312486-rumqopg0	256	6	subgroup	subgroup	NN
cord-312486-rumqopg0	256	7	of	of	IN
cord-312486-rumqopg0	256	8	approximately	approximately	RB
cord-312486-rumqopg0	256	9	twenty	twenty	CD
cord-312486-rumqopg0	256	10	percent	percent	NN
cord-312486-rumqopg0	256	11	of	of	IN
cord-312486-rumqopg0	256	12	severe	severe	JJ
cord-312486-rumqopg0	256	13	COVID-19	covid-19	JJ
cord-312486-rumqopg0	256	14	patients	patient	NNS
cord-312486-rumqopg0	256	15	that	that	WDT
cord-312486-rumqopg0	256	16	lack	lack	VBP
cord-312486-rumqopg0	256	17	detectable	detectable	JJ
cord-312486-rumqopg0	256	18	lymphocyte	lymphocyte	NN
cord-312486-rumqopg0	256	19	response	response	NN
cord-312486-rumqopg0	256	20	to	to	IN
cord-312486-rumqopg0	256	21	the	the	DT
cord-312486-rumqopg0	256	22	infection	infection	NN
cord-312486-rumqopg0	256	23	,	,	,
cord-312486-rumqopg0	256	24	suggesting	suggest	VBG
cord-312486-rumqopg0	256	25	a	a	DT
cord-312486-rumqopg0	256	26	total	total	JJ
cord-312486-rumqopg0	256	27	failure	failure	NN
cord-312486-rumqopg0	256	28	of	of	IN
cord-312486-rumqopg0	256	29	immune	immune	JJ
cord-312486-rumqopg0	256	30	activation	activation	NN
cord-312486-rumqopg0	256	31	.	.	.
cord-312486-rumqopg0	257	1	Further	further	RB
cord-312486-rumqopg0	257	2	,	,	,
cord-312486-rumqopg0	257	3	these	these	DT
cord-312486-rumqopg0	257	4	investigators	investigator	NNS
cord-312486-rumqopg0	257	5	emphasize	emphasize	VBP
cord-312486-rumqopg0	257	6	that	that	IN
cord-312486-rumqopg0	257	7	the	the	DT
cord-312486-rumqopg0	257	8	typical	typical	JJ
cord-312486-rumqopg0	257	9	Tcell	Tcell	NNP
cord-312486-rumqopg0	257	10	/	/	SYM
cord-312486-rumqopg0	257	11	B	b	NN
cord-312486-rumqopg0	257	12	-	-	HYPH
cord-312486-rumqopg0	257	13	cell	cell	NN
cord-312486-rumqopg0	257	14	communication	communication	NN
cord-312486-rumqopg0	257	15	and	and	CC
cord-312486-rumqopg0	257	16	cooperation	cooperation	NN
cord-312486-rumqopg0	257	17	,	,	,
cord-312486-rumqopg0	257	18	the	the	DT
cord-312486-rumqopg0	257	19	adaptive	adaptive	JJ
cord-312486-rumqopg0	257	20	immune	immune	JJ
cord-312486-rumqopg0	257	21	system	system	NN
cord-312486-rumqopg0	257	22	depends	depend	VBZ
cord-312486-rumqopg0	257	23	on	on	IN
cord-312486-rumqopg0	257	24	,	,	,
cord-312486-rumqopg0	257	25	is	be	VBZ
cord-312486-rumqopg0	257	26	practically	practically	RB
cord-312486-rumqopg0	257	27	nonexistent	nonexistent	JJ
cord-312486-rumqopg0	257	28	in	in	IN
cord-312486-rumqopg0	257	29	some	some	DT
cord-312486-rumqopg0	257	30	COVID-19	covid-19	CD
cord-312486-rumqopg0	257	31	patients	patient	NNS
cord-312486-rumqopg0	257	32	.	.	.
cord-312486-rumqopg0	258	1	Lucas	Lucas	NNP
cord-312486-rumqopg0	258	2	et	et	NNP
cord-312486-rumqopg0	258	3	al	al	NNP
cord-312486-rumqopg0	258	4	.	.	.
cord-312486-rumqopg0	259	1	,	,	,
cord-312486-rumqopg0	259	2	[	[	-LRB-
cord-312486-rumqopg0	259	3	126	126	CD
cord-312486-rumqopg0	259	4	]	]	-RRB-
cord-312486-rumqopg0	259	5	confirmed	confirm	VBD
cord-312486-rumqopg0	259	6	an	an	DT
cord-312486-rumqopg0	259	7	overall	overall	JJ
cord-312486-rumqopg0	259	8	increase	increase	NN
cord-312486-rumqopg0	259	9	in	in	IN
cord-312486-rumqopg0	259	10	innate	innate	JJ
cord-312486-rumqopg0	259	11	cell	cell	NN
cord-312486-rumqopg0	259	12	lineages	lineage	NNS
cord-312486-rumqopg0	259	13	,	,	,
cord-312486-rumqopg0	259	14	reduction	reduction	NN
cord-312486-rumqopg0	259	15	in	in	IN
cord-312486-rumqopg0	259	16	HLA	HLA	NNP
cord-312486-rumqopg0	259	17	class	class	NN
cord-312486-rumqopg0	259	18	II	II	NNP
cord-312486-rumqopg0	259	19	molecules	molecule	NNS
cord-312486-rumqopg0	259	20	on	on	IN
cord-312486-rumqopg0	259	21	monocytes	monocyte	NNS
cord-312486-rumqopg0	259	22	,	,	,
cord-312486-rumqopg0	259	23	and	and	CC
cord-312486-rumqopg0	259	24	early	early	JJ
cord-312486-rumqopg0	259	25	surge	surge	NN
cord-312486-rumqopg0	259	26	in	in	IN
cord-312486-rumqopg0	259	27	cytokines	cytokine	NNS
cord-312486-rumqopg0	259	28	with	with	IN
cord-312486-rumqopg0	259	29	parallel	parallel	JJ
cord-312486-rumqopg0	259	30	reduction	reduction	NN
cord-312486-rumqopg0	259	31	in	in	IN
cord-312486-rumqopg0	259	32	T	t	NN
cord-312486-rumqopg0	259	33	cells	cell	NNS
cord-312486-rumqopg0	259	34	,	,	,
cord-312486-rumqopg0	259	35	observed	observe	VBN
cord-312486-rumqopg0	259	36	by	by	IN
cord-312486-rumqopg0	259	37	many	many	JJ
cord-312486-rumqopg0	259	38	other	other	JJ
cord-312486-rumqopg0	259	39	studies	study	NNS
cord-312486-rumqopg0	259	40	.	.	.
cord-312486-rumqopg0	260	1	In	in	IN
cord-312486-rumqopg0	260	2	addition	addition	NN
cord-312486-rumqopg0	260	3	,	,	,
cord-312486-rumqopg0	260	4	according	accord	VBG
cord-312486-rumqopg0	260	5	to	to	IN
cord-312486-rumqopg0	260	6	these	these	DT
cord-312486-rumqopg0	260	7	investigators	investigator	NNS
cord-312486-rumqopg0	260	8	the	the	DT
cord-312486-rumqopg0	260	9	immune	immune	JJ
cord-312486-rumqopg0	260	10	responses	response	NNS
cord-312486-rumqopg0	260	11	to	to	IN
cord-312486-rumqopg0	260	12	pathogens	pathogen	NNS
cord-312486-rumqopg0	260	13	can	can	MD
cord-312486-rumqopg0	260	14	be	be	VB
cord-312486-rumqopg0	260	15	roughly	roughly	RB
cord-312486-rumqopg0	260	16	grouped	group	VBN
cord-312486-rumqopg0	260	17	into	into	IN
cord-312486-rumqopg0	260	18	three	three	CD
cord-312486-rumqopg0	260	19	categories	category	NNS
cord-312486-rumqopg0	260	20	characterized	characterize	VBN
cord-312486-rumqopg0	260	21	by	by	IN
cord-312486-rumqopg0	260	22	different	different	JJ
cord-312486-rumqopg0	260	23	sets	set	NNS
cord-312486-rumqopg0	260	24	of	of	IN
cord-312486-rumqopg0	260	25	immune	immune	JJ
cord-312486-rumqopg0	260	26	cells	cell	NNS
cord-312486-rumqopg0	260	27	and	and	CC
cord-312486-rumqopg0	260	28	cytokine	cytokine	NN
cord-312486-rumqopg0	260	29	signals	signal	NNS
cord-312486-rumqopg0	260	30	used	use	VBN
cord-312486-rumqopg0	260	31	:	:	:
cord-312486-rumqopg0	260	32	type	type	VB
cord-312486-rumqopg0	260	33	1-broadly	1-broadly	NNP
cord-312486-rumqopg0	260	34	T	t	NN
cord-312486-rumqopg0	260	35	H	h	NN
cord-312486-rumqopg0	260	36	1	1	CD
cord-312486-rumqopg0	260	37	responses	response	NNS
cord-312486-rumqopg0	260	38	directed	direct	VBN
cord-312486-rumqopg0	260	39	against	against	IN
cord-312486-rumqopg0	260	40	viruses	virus	NNS
cord-312486-rumqopg0	260	41	and	and	CC
cord-312486-rumqopg0	260	42	intracellular	intracellular	JJ
cord-312486-rumqopg0	260	43	bacteria	bacteria	NNS
cord-312486-rumqopg0	260	44	;	;	:
cord-312486-rumqopg0	260	45	type	type	NN
cord-312486-rumqopg0	260	46	2-directed	2-directed	CD
cord-312486-rumqopg0	260	47	against	against	IN
cord-312486-rumqopg0	260	48	parasites	parasite	NNS
cord-312486-rumqopg0	260	49	that	that	WDT
cord-312486-rumqopg0	260	50	do	do	VBP
cord-312486-rumqopg0	260	51	not	not	RB
cord-312486-rumqopg0	260	52	invade	invade	VB
cord-312486-rumqopg0	260	53	cells	cell	NNS
cord-312486-rumqopg0	260	54	;	;	:
cord-312486-rumqopg0	260	55	and	and	CC
cord-312486-rumqopg0	260	56	type	type	VB
cord-312486-rumqopg0	260	57	3-directed	3-directed	CD
cord-312486-rumqopg0	260	58	against	against	IN
cord-312486-rumqopg0	260	59	fungi	fungus	NNS
cord-312486-rumqopg0	260	60	and	and	CC
cord-312486-rumqopg0	260	61	bacteria	bacteria	NNS
cord-312486-rumqopg0	260	62	that	that	WDT
cord-312486-rumqopg0	260	63	can	can	MD
cord-312486-rumqopg0	260	64	survive	survive	VB
cord-312486-rumqopg0	260	65	outside	outside	IN
cord-312486-rumqopg0	260	66	the	the	DT
cord-312486-rumqopg0	260	67	cells	cell	NNS
cord-312486-rumqopg0	260	68	.	.	.
cord-312486-rumqopg0	261	1	Type	type	NN
cord-312486-rumqopg0	261	2	1	1	CD
cord-312486-rumqopg0	261	3	immune	immune	JJ
cord-312486-rumqopg0	261	4	response	response	NN
cord-312486-rumqopg0	261	5	expected	expect	VBN
cord-312486-rumqopg0	261	6	in	in	IN
cord-312486-rumqopg0	261	7	SARS	SARS	NNP
cord-312486-rumqopg0	261	8	-	-	HYPH
cord-312486-rumqopg0	261	9	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	261	10	infection	infection	NN
cord-312486-rumqopg0	261	11	was	be	VBD
cord-312486-rumqopg0	261	12	seen	see	VBN
cord-312486-rumqopg0	261	13	in	in	IN
cord-312486-rumqopg0	261	14	mild	mild	JJ
cord-312486-rumqopg0	261	15	to	to	IN
cord-312486-rumqopg0	261	16	moderate	moderate	JJ
cord-312486-rumqopg0	261	17	cases	case	NNS
cord-312486-rumqopg0	261	18	,	,	,
cord-312486-rumqopg0	261	19	while	while	IN
cord-312486-rumqopg0	261	20	in	in	IN
cord-312486-rumqopg0	261	21	severe	severe	JJ
cord-312486-rumqopg0	261	22	cases	case	NNS
cord-312486-rumqopg0	261	23	the	the	DT
cord-312486-rumqopg0	261	24	immune	immune	JJ
cord-312486-rumqopg0	261	25	system	system	NN
cord-312486-rumqopg0	261	26	seemed	seem	VBD
cord-312486-rumqopg0	261	27	to	to	TO
cord-312486-rumqopg0	261	28	invest	invest	VB
cord-312486-rumqopg0	261	29	too	too	RB
cord-312486-rumqopg0	261	30	many	many	JJ
cord-312486-rumqopg0	261	31	resources	resource	NNS
cord-312486-rumqopg0	261	32	in	in	IN
cord-312486-rumqopg0	261	33	non	non	JJ
cord-312486-rumqopg0	261	34	-	-	JJ
cord-312486-rumqopg0	261	35	appropriate	appropriate	JJ
cord-312486-rumqopg0	261	36	type	type	NN
cord-312486-rumqopg0	261	37	2	2	CD
cord-312486-rumqopg0	261	38	and	and	CC
cord-312486-rumqopg0	261	39	type	type	NN
cord-312486-rumqopg0	261	40	3	3	CD
cord-312486-rumqopg0	261	41	immune	immune	NN
cord-312486-rumqopg0	261	42	signaling	signaling	NN
cord-312486-rumqopg0	261	43	.	.	.
cord-312486-rumqopg0	262	1	This	this	DT
cord-312486-rumqopg0	262	2	immune	immune	JJ
cord-312486-rumqopg0	262	3	disintegration	disintegration	NN
cord-312486-rumqopg0	262	4	,	,	,
cord-312486-rumqopg0	262	5	the	the	DT
cord-312486-rumqopg0	262	6	investigators	investigator	NNS
cord-312486-rumqopg0	262	7	have	have	VBP
cord-312486-rumqopg0	262	8	dubbed	dub	VBN
cord-312486-rumqopg0	262	9	as	as	IN
cord-312486-rumqopg0	262	10	-misfiring,‖	-misfiring,‖	JJ
cord-312486-rumqopg0	262	11	seems	seem	NNS
cord-312486-rumqopg0	262	12	to	to	TO
cord-312486-rumqopg0	262	13	extend	extend	VB
cord-312486-rumqopg0	262	14	to	to	IN
cord-312486-rumqopg0	262	15	the	the	DT
cord-312486-rumqopg0	262	16	realm	realm	NN
cord-312486-rumqopg0	262	17	of	of	IN
cord-312486-rumqopg0	262	18	T	T	NNP
cord-312486-rumqopg0	262	19	and	and	CC
cord-312486-rumqopg0	262	20	B	b	NN
cord-312486-rumqopg0	262	21	lymphocytes	lymphocyte	NNS
cord-312486-rumqopg0	262	22	[	[	-LRB-
cord-312486-rumqopg0	262	23	126	126	CD
cord-312486-rumqopg0	262	24	]	]	-RRB-
cord-312486-rumqopg0	262	25	.	.	.
cord-312486-rumqopg0	263	1	Other	other	JJ
cord-312486-rumqopg0	263	2	investigators	investigator	NNS
cord-312486-rumqopg0	263	3	describe	describe	VBP
cord-312486-rumqopg0	263	4	the	the	DT
cord-312486-rumqopg0	263	5	catastrophic	catastrophic	JJ
cord-312486-rumqopg0	263	6	CoV	cov	NN
cord-312486-rumqopg0	263	7	disease	disease	NN
cord-312486-rumqopg0	263	8	as	as	IN
cord-312486-rumqopg0	263	9	a	a	DT
cord-312486-rumqopg0	263	10	lack	lack	NN
cord-312486-rumqopg0	263	11	of	of	IN
cord-312486-rumqopg0	263	12	switch	switch	NN
cord-312486-rumqopg0	263	13	from	from	IN
cord-312486-rumqopg0	263	14	an	an	DT
cord-312486-rumqopg0	263	15	innate	innate	JJ
cord-312486-rumqopg0	263	16	immune	immune	JJ
cord-312486-rumqopg0	263	17	response	response	NN
cord-312486-rumqopg0	263	18	to	to	IN
cord-312486-rumqopg0	263	19	an	an	DT
cord-312486-rumqopg0	263	20	adaptive	adaptive	JJ
cord-312486-rumqopg0	263	21	immune	immune	JJ
cord-312486-rumqopg0	263	22	response	response	NN
cord-312486-rumqopg0	263	23	[	[	-LRB-
cord-312486-rumqopg0	263	24	13	13	CD
cord-312486-rumqopg0	263	25	]	]	-RRB-
cord-312486-rumqopg0	263	26	.	.	.
cord-312486-rumqopg0	264	1	These	these	DT
cord-312486-rumqopg0	264	2	depictions	depiction	NNS
cord-312486-rumqopg0	264	3	of	of	IN
cord-312486-rumqopg0	264	4	the	the	DT
cord-312486-rumqopg0	264	5	immune	immune	JJ
cord-312486-rumqopg0	264	6	response	response	NN
cord-312486-rumqopg0	264	7	in	in	IN
cord-312486-rumqopg0	264	8	severe	severe	JJ
cord-312486-rumqopg0	264	9	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	264	10	are	be	VBP
cord-312486-rumqopg0	264	11	symbolically	symbolically	RB
cord-312486-rumqopg0	264	12	captured	capture	VBN
cord-312486-rumqopg0	264	13	in	in	IN
cord-312486-rumqopg0	264	14	Fig.1	Fig.1	NNP
cord-312486-rumqopg0	264	15	.	.	.
cord-312486-rumqopg0	265	1	The	the	DT
cord-312486-rumqopg0	265	2	antigen	antigen	NN
cord-312486-rumqopg0	265	3	specificity	specificity	NN
cord-312486-rumqopg0	265	4	of	of	IN
cord-312486-rumqopg0	265	5	SARS	SARS	NNP
cord-312486-rumqopg0	265	6	-	-	HYPH
cord-312486-rumqopg0	265	7	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	265	8	T	t	NN
cord-312486-rumqopg0	265	9	cells	cell	NNS
cord-312486-rumqopg0	265	10	have	have	VBP
cord-312486-rumqopg0	265	11	just	just	RB
cord-312486-rumqopg0	265	12	started	start	VBN
cord-312486-rumqopg0	265	13	to	to	TO
cord-312486-rumqopg0	265	14	be	be	VB
cord-312486-rumqopg0	265	15	characterized	characterize	VBN
cord-312486-rumqopg0	265	16	in	in	IN
cord-312486-rumqopg0	265	17	COVID-19	covid-19	JJ
cord-312486-rumqopg0	265	18	patients	patient	NNS
cord-312486-rumqopg0	265	19	[	[	-LRB-
cord-312486-rumqopg0	265	20	129	129	CD
cord-312486-rumqopg0	265	21	,	,	,
cord-312486-rumqopg0	265	22	130	130	CD
cord-312486-rumqopg0	265	23	]	]	-RRB-
cord-312486-rumqopg0	265	24	and	and	CC
cord-312486-rumqopg0	265	25	their	-PRON-	PRP$
cord-312486-rumqopg0	265	26	potential	potential	JJ
cord-312486-rumqopg0	265	27	protective	protective	JJ
cord-312486-rumqopg0	265	28	role	role	NN
cord-312486-rumqopg0	265	29	awaits	await	VBZ
cord-312486-rumqopg0	265	30	additional	additional	JJ
cord-312486-rumqopg0	265	31	research	research	NN
cord-312486-rumqopg0	265	32	.	.	.
cord-312486-rumqopg0	266	1	However	however	RB
cord-312486-rumqopg0	266	2	,	,	,
cord-312486-rumqopg0	266	3	it	-PRON-	PRP
cord-312486-rumqopg0	266	4	is	be	VBZ
cord-312486-rumqopg0	266	5	already	already	RB
cord-312486-rumqopg0	266	6	clear	clear	JJ
cord-312486-rumqopg0	266	7	that	that	IN
cord-312486-rumqopg0	266	8	patients	patient	NNS
cord-312486-rumqopg0	266	9	who	who	WP
cord-312486-rumqopg0	266	10	recovered	recover	VBD
cord-312486-rumqopg0	266	11	show	show	NN
cord-312486-rumqopg0	266	12	specificity	specificity	NN
cord-312486-rumqopg0	266	13	for	for	IN
cord-312486-rumqopg0	266	14	multiple	multiple	JJ
cord-312486-rumqopg0	266	15	SARS	SARS	NNP
cord-312486-rumqopg0	266	16	-	-	HYPH
cord-312486-rumqopg0	266	17	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	266	18	proteins	protein	NNS
cord-312486-rumqopg0	266	19	,	,	,
cord-312486-rumqopg0	266	20	not	not	RB
cord-312486-rumqopg0	266	21	only	only	RB
cord-312486-rumqopg0	266	22	spike	spike	NN
cord-312486-rumqopg0	266	23	protein	protein	NN
cord-312486-rumqopg0	266	24	.	.	.
cord-312486-rumqopg0	267	1	Interestingly	interestingly	RB
cord-312486-rumqopg0	267	2	,	,	,
cord-312486-rumqopg0	267	3	cross	cross	JJ
cord-312486-rumqopg0	267	4	-	-	JJ
cord-312486-rumqopg0	267	5	reactive	reactive	JJ
cord-312486-rumqopg0	267	6	memory	memory	NN
cord-312486-rumqopg0	267	7	CD4	CD4	NNP
cord-312486-rumqopg0	267	8	+	+	CC
cord-312486-rumqopg0	267	9	and	and	CC
cord-312486-rumqopg0	267	10	CD8	CD8	NNP
cord-312486-rumqopg0	267	11	+	+	CC
cord-312486-rumqopg0	267	12	T	T	NNP
cord-312486-rumqopg0	267	13	cells	cell	NNS
cord-312486-rumqopg0	267	14	are	be	VBP
cord-312486-rumqopg0	267	15	also	also	RB
cord-312486-rumqopg0	267	16	found	find	VBN
cord-312486-rumqopg0	267	17	in	in	IN
cord-312486-rumqopg0	267	18	~	~	CD
cord-312486-rumqopg0	267	19	50	50	CD
cord-312486-rumqopg0	267	20	%	%	NN
cord-312486-rumqopg0	267	21	of	of	IN
cord-312486-rumqopg0	267	22	subjects	subject	NNS
cord-312486-rumqopg0	267	23	who	who	WP
cord-312486-rumqopg0	267	24	have	have	VBP
cord-312486-rumqopg0	267	25	never	never	RB
cord-312486-rumqopg0	267	26	been	be	VBN
cord-312486-rumqopg0	267	27	exposed	expose	VBN
cord-312486-rumqopg0	267	28	to	to	IN
cord-312486-rumqopg0	267	29	SARS	SARS	NNP
cord-312486-rumqopg0	267	30	-	-	HYPH
cord-312486-rumqopg0	267	31	CoV-1/2	CoV-1/2	NNP
cord-312486-rumqopg0	267	32	[	[	-LRB-
cord-312486-rumqopg0	267	33	129	129	CD
cord-312486-rumqopg0	267	34	,	,	,
cord-312486-rumqopg0	267	35	130	130	CD
cord-312486-rumqopg0	267	36	]	]	-RRB-
cord-312486-rumqopg0	267	37	.	.	.
cord-312486-rumqopg0	268	1	While	while	IN
cord-312486-rumqopg0	268	2	SARS	SARS	NNP
cord-312486-rumqopg0	268	3	-	-	HYPH
cord-312486-rumqopg0	268	4	CoV-1/2	CoV-1/2	NNP
cord-312486-rumqopg0	268	5	unexposed	unexposed	JJ
cord-312486-rumqopg0	268	6	donors	donor	NNS
cord-312486-rumqopg0	268	7	can	can	MD
cord-312486-rumqopg0	268	8	recognize	recognize	VB
cord-312486-rumqopg0	268	9	both	both	DT
cord-312486-rumqopg0	268	10	structural	structural	JJ
cord-312486-rumqopg0	268	11	and	and	CC
cord-312486-rumqopg0	268	12	nonstructural	nonstructural	JJ
cord-312486-rumqopg0	268	13	viral	viral	JJ
cord-312486-rumqopg0	268	14	proteins	protein	NNS
cord-312486-rumqopg0	268	15	,	,	,
cord-312486-rumqopg0	268	16	nonstructural	nonstructural	JJ
cord-312486-rumqopg0	268	17	ORF-1-NSP7/13-specific	ORF-1-NSP7/13-specific	NNP
cord-312486-rumqopg0	268	18	T	t	NN
cord-312486-rumqopg0	268	19	cells	cell	NNS
cord-312486-rumqopg0	268	20	are	be	VBP
cord-312486-rumqopg0	268	21	often	often	RB
cord-312486-rumqopg0	268	22	dominant	dominant	JJ
cord-312486-rumqopg0	268	23	.	.	.
cord-312486-rumqopg0	269	1	In	in	IN
cord-312486-rumqopg0	269	2	contrast	contrast	NN
cord-312486-rumqopg0	269	3	,	,	,
cord-312486-rumqopg0	269	4	SARS	SARS	NNP
cord-312486-rumqopg0	269	5	-	-	HYPH
cord-312486-rumqopg0	269	6	CoV-1/2	CoV-1/2	NNP
cord-312486-rumqopg0	269	7	recovered	recover	VBD
cord-312486-rumqopg0	269	8	individual	individual	NN
cord-312486-rumqopg0	269	9	preferentially	preferentially	RB
cord-312486-rumqopg0	269	10	recognize	recognize	VB
cord-312486-rumqopg0	269	11	structural	structural	JJ
cord-312486-rumqopg0	269	12	proteins	protein	NNS
cord-312486-rumqopg0	269	13	[	[	-LRB-
cord-312486-rumqopg0	269	14	130	130	CD
cord-312486-rumqopg0	269	15	]	]	-RRB-
cord-312486-rumqopg0	269	16	.	.	.
cord-312486-rumqopg0	270	1	At	at	IN
cord-312486-rumqopg0	270	2	present	present	JJ
cord-312486-rumqopg0	270	3	no	no	DT
cord-312486-rumqopg0	270	4	satisfactory	satisfactory	JJ
cord-312486-rumqopg0	270	5	explanation	explanation	NN
cord-312486-rumqopg0	270	6	for	for	IN
cord-312486-rumqopg0	270	7	this	this	DT
cord-312486-rumqopg0	270	8	phenomenon	phenomenon	NN
cord-312486-rumqopg0	270	9	has	have	VBZ
cord-312486-rumqopg0	270	10	been	be	VBN
cord-312486-rumqopg0	270	11	offered	offer	VBN
cord-312486-rumqopg0	270	12	.	.	.
cord-312486-rumqopg0	271	1	Also	also	RB
cord-312486-rumqopg0	271	2	unclear	unclear	JJ
cord-312486-rumqopg0	271	3	is	be	VBZ
cord-312486-rumqopg0	271	4	how	how	WRB
cord-312486-rumqopg0	271	5	these	these	DT
cord-312486-rumqopg0	271	6	preexisting	preexisting	JJ
cord-312486-rumqopg0	271	7	memory	memory	NN
cord-312486-rumqopg0	271	8	T	t	NN
cord-312486-rumqopg0	271	9	cells	cell	NNS
cord-312486-rumqopg0	271	10	,	,	,
cord-312486-rumqopg0	271	11	which	which	WDT
cord-312486-rumqopg0	271	12	are	be	VBP
cord-312486-rumqopg0	271	13	presumably	presumably	RB
cord-312486-rumqopg0	271	14	generated	generate	VBN
cord-312486-rumqopg0	271	15	in	in	IN
cord-312486-rumqopg0	271	16	response	response	NN
cord-312486-rumqopg0	271	17	to	to	IN
cord-312486-rumqopg0	271	18	human	human	JJ
cord-312486-rumqopg0	271	19	common	common	JJ
cord-312486-rumqopg0	271	20	cold	cold	NNP
cord-312486-rumqopg0	271	21	CoV	cov	NN
cord-312486-rumqopg0	271	22	,	,	,
cord-312486-rumqopg0	271	23	affect	affect	VBP
cord-312486-rumqopg0	271	24	immunity	immunity	NN
cord-312486-rumqopg0	271	25	or	or	CC
cord-312486-rumqopg0	271	26	pathology	pathology	NN
cord-312486-rumqopg0	271	27	upon	upon	IN
cord-312486-rumqopg0	271	28	SARS	SARS	NNP
cord-312486-rumqopg0	271	29	-	-	HYPH
cord-312486-rumqopg0	271	30	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	271	31	infection	infection	NN
cord-312486-rumqopg0	271	32	.	.	.
cord-312486-rumqopg0	272	1	Heterologous	heterologous	JJ
cord-312486-rumqopg0	272	2	viral	viral	JJ
cord-312486-rumqopg0	272	3	T	t	NN
cord-312486-rumqopg0	272	4	cell	cell	NN
cord-312486-rumqopg0	272	5	immunity	immunity	NN
cord-312486-rumqopg0	272	6	and	and	CC
cord-312486-rumqopg0	272	7	immunopathogenesis	immunopathogenesis	NN
cord-312486-rumqopg0	272	8	-	-	:
cord-312486-rumqopg0	272	9	an	an	DT
cord-312486-rumqopg0	272	10	important	important	JJ
cord-312486-rumqopg0	272	11	consideration	consideration	NN
cord-312486-rumqopg0	272	12	that	that	WDT
cord-312486-rumqopg0	272	13	has	have	VBZ
cord-312486-rumqopg0	272	14	not	not	RB
cord-312486-rumqopg0	272	15	yet	yet	RB
cord-312486-rumqopg0	272	16	received	receive	VBN
cord-312486-rumqopg0	272	17	sufficient	sufficient	JJ
cord-312486-rumqopg0	272	18	consideration	consideration	NN
cord-312486-rumqopg0	272	19	in	in	IN
cord-312486-rumqopg0	272	20	the	the	DT
cord-312486-rumqopg0	272	21	current	current	JJ
cord-312486-rumqopg0	272	22	viral	viral	JJ
cord-312486-rumqopg0	272	23	pandemic	pandemic	NN
cord-312486-rumqopg0	272	24	,	,	,
cord-312486-rumqopg0	272	25	is	be	VBZ
cord-312486-rumqopg0	272	26	highly	highly	RB
cord-312486-rumqopg0	272	27	relevant	relevant	JJ
cord-312486-rumqopg0	272	28	to	to	IN
cord-312486-rumqopg0	272	29	the	the	DT
cord-312486-rumqopg0	272	30	observations	observation	NNS
cord-312486-rumqopg0	272	31	of	of	IN
cord-312486-rumqopg0	272	32	cross	cross	JJ
cord-312486-rumqopg0	272	33	-	-	JJ
cord-312486-rumqopg0	272	34	reactive	reactive	JJ
cord-312486-rumqopg0	272	35	T	t	NN
cord-312486-rumqopg0	272	36	-	-	HYPH
cord-312486-rumqopg0	272	37	cell	cell	NN
cord-312486-rumqopg0	272	38	responses	response	NNS
cord-312486-rumqopg0	272	39	in	in	IN
cord-312486-rumqopg0	272	40	non	non	JJ
cord-312486-rumqopg0	272	41	-	-	JJ
cord-312486-rumqopg0	272	42	exposed	expose	VBN
cord-312486-rumqopg0	272	43	subjects	subject	NNS
cord-312486-rumqopg0	272	44	.	.	.
cord-312486-rumqopg0	273	1	In	in	IN
cord-312486-rumqopg0	273	2	fact	fact	NN
cord-312486-rumqopg0	273	3	,	,	,
cord-312486-rumqopg0	273	4	only	only	RB
cord-312486-rumqopg0	273	5	laboratory	laboratory	NN
cord-312486-rumqopg0	273	6	animals	animal	NNS
cord-312486-rumqopg0	273	7	kept	keep	VBD
cord-312486-rumqopg0	273	8	in	in	IN
cord-312486-rumqopg0	273	9	pathogen	pathogen	NN
cord-312486-rumqopg0	273	10	free	free	JJ
cord-312486-rumqopg0	273	11	conditions	condition	NNS
cord-312486-rumqopg0	273	12	are	be	VBP
cord-312486-rumqopg0	273	13	naïve	naïve	JJ
cord-312486-rumqopg0	273	14	.	.	.
cord-312486-rumqopg0	274	1	No	no	DT
cord-312486-rumqopg0	274	2	human	human	JJ
cord-312486-rumqopg0	274	3	more	more	JJR
cord-312486-rumqopg0	274	4	than	than	IN
cord-312486-rumqopg0	274	5	a	a	DT
cord-312486-rumqopg0	274	6	few	few	JJ
cord-312486-rumqopg0	274	7	weeks	week	NNS
cord-312486-rumqopg0	274	8	old	old	JJ
cord-312486-rumqopg0	274	9	is	be	VBZ
cord-312486-rumqopg0	274	10	immunologically	immunologically	RB
cord-312486-rumqopg0	274	11	naïve	naïve	JJ
cord-312486-rumqopg0	274	12	[	[	-LRB-
cord-312486-rumqopg0	274	13	131	131	CD
cord-312486-rumqopg0	274	14	]	]	-RRB-
cord-312486-rumqopg0	274	15	.	.	.
cord-312486-rumqopg0	275	1	The	the	DT
cord-312486-rumqopg0	275	2	history	history	NN
cord-312486-rumqopg0	275	3	of	of	IN
cord-312486-rumqopg0	275	4	previous	previous	JJ
cord-312486-rumqopg0	275	5	exposure	exposure	NN
cord-312486-rumqopg0	275	6	,	,	,
cord-312486-rumqopg0	275	7	not	not	RB
cord-312486-rumqopg0	275	8	only	only	RB
cord-312486-rumqopg0	275	9	to	to	IN
cord-312486-rumqopg0	275	10	related	relate	VBN
cord-312486-rumqopg0	275	11	,	,	,
cord-312486-rumqopg0	275	12	but	but	CC
cord-312486-rumqopg0	275	13	also	also	RB
cord-312486-rumqopg0	275	14	to	to	IN
cord-312486-rumqopg0	275	15	unrelated	unrelated	JJ
cord-312486-rumqopg0	275	16	microorganisms	microorganism	NNS
cord-312486-rumqopg0	275	17	,	,	,
cord-312486-rumqopg0	275	18	can	can	MD
cord-312486-rumqopg0	275	19	greatly	greatly	RB
cord-312486-rumqopg0	275	20	alter	alter	VB
cord-312486-rumqopg0	275	21	the	the	DT
cord-312486-rumqopg0	275	22	host	host	NN
cord-312486-rumqopg0	275	23	's	's	POS
cord-312486-rumqopg0	275	24	immune	immune	JJ
cord-312486-rumqopg0	275	25	response	response	NN
cord-312486-rumqopg0	275	26	to	to	IN
cord-312486-rumqopg0	275	27	a	a	DT
cord-312486-rumqopg0	275	28	viral	viral	JJ
cord-312486-rumqopg0	275	29	infection	infection	NN
cord-312486-rumqopg0	275	30	and	and	CC
cord-312486-rumqopg0	275	31	can	can	MD
cord-312486-rumqopg0	275	32	change	change	VB
cord-312486-rumqopg0	275	33	the	the	DT
cord-312486-rumqopg0	275	34	course	course	NN
cord-312486-rumqopg0	275	35	of	of	IN
cord-312486-rumqopg0	275	36	disease	disease	NN
cord-312486-rumqopg0	275	37	[	[	-LRB-
cord-312486-rumqopg0	275	38	131	131	CD
cord-312486-rumqopg0	275	39	]	]	-RRB-
cord-312486-rumqopg0	275	40	.	.	.
cord-312486-rumqopg0	276	1	In	in	IN
cord-312486-rumqopg0	276	2	fact	fact	NN
cord-312486-rumqopg0	276	3	,	,	,
cord-312486-rumqopg0	276	4	it	-PRON-	PRP
cord-312486-rumqopg0	276	5	is	be	VBZ
cord-312486-rumqopg0	276	6	very	very	RB
cord-312486-rumqopg0	276	7	likely	likely	JJ
cord-312486-rumqopg0	276	8	that	that	IN
cord-312486-rumqopg0	276	9	this	this	DT
cord-312486-rumqopg0	276	10	phenomenon	phenomenon	NN
cord-312486-rumqopg0	276	11	is	be	VBZ
cord-312486-rumqopg0	276	12	a	a	DT
cord-312486-rumqopg0	276	13	common	common	JJ
cord-312486-rumqopg0	276	14	feature	feature	NN
cord-312486-rumqopg0	276	15	of	of	IN
cord-312486-rumqopg0	276	16	human	human	JJ
cord-312486-rumqopg0	276	17	viral	viral	JJ
cord-312486-rumqopg0	276	18	infections	infection	NNS
cord-312486-rumqopg0	276	19	.	.	.
cord-312486-rumqopg0	277	1	T	t	NN
cord-312486-rumqopg0	277	2	cells	cell	NNS
cord-312486-rumqopg0	277	3	have	have	VBP
cord-312486-rumqopg0	277	4	high	high	JJ
cord-312486-rumqopg0	277	5	levels	level	NNS
cord-312486-rumqopg0	277	6	of	of	IN
cord-312486-rumqopg0	277	7	J	J	NNP
cord-312486-rumqopg0	277	8	o	o	NN
cord-312486-rumqopg0	277	9	u	u	NN
cord-312486-rumqopg0	277	10	r	r	NNP
cord-312486-rumqopg0	277	11	n	n	NN
cord-312486-rumqopg0	277	12	a	a	DT
cord-312486-rumqopg0	277	13	l	l	NN
cord-312486-rumqopg0	277	14	P	p	NN
cord-312486-rumqopg0	277	15	r	r	NN
cord-312486-rumqopg0	277	16	e	e	NN
cord-312486-rumqopg0	277	17	-p	-p	NN
cord-312486-rumqopg0	278	1	r	r	NNP
cord-312486-rumqopg0	278	2	o	o	NN
cord-312486-rumqopg0	278	3	o	o	NN
cord-312486-rumqopg0	278	4	f	f	NN
cord-312486-rumqopg0	278	5	cross	cross	NN
cord-312486-rumqopg0	278	6	-	-	NN
cord-312486-rumqopg0	278	7	reactivity	reactivity	NN
cord-312486-rumqopg0	278	8	because	because	IN
cord-312486-rumqopg0	278	9	the	the	DT
cord-312486-rumqopg0	278	10	TCR	TCR	NNP
cord-312486-rumqopg0	278	11	first	first	RB
cord-312486-rumqopg0	278	12	scans	scan	VBZ
cord-312486-rumqopg0	278	13	the	the	DT
cord-312486-rumqopg0	278	14	peptide	peptide	NN
cord-312486-rumqopg0	278	15	-	-	HYPH
cord-312486-rumqopg0	278	16	HLA	HLA	NNP
cord-312486-rumqopg0	278	17	complex	complex	NN
cord-312486-rumqopg0	278	18	by	by	IN
cord-312486-rumqopg0	278	19	binding	bind	VBG
cord-312486-rumqopg0	278	20	to	to	IN
cord-312486-rumqopg0	278	21	the	the	DT
cord-312486-rumqopg0	278	22	HLA	HLA	NNP
cord-312486-rumqopg0	278	23	,	,	,
cord-312486-rumqopg0	278	24	and	and	CC
cord-312486-rumqopg0	278	25	then	then	RB
cord-312486-rumqopg0	278	26	it	-PRON-	PRP
cord-312486-rumqopg0	278	27	molds	mold	VBZ
cord-312486-rumqopg0	278	28	itself	-PRON-	PRP
cord-312486-rumqopg0	278	29	around	around	IN
cord-312486-rumqopg0	278	30	the	the	DT
cord-312486-rumqopg0	278	31	peptide	peptide	NN
cord-312486-rumqopg0	278	32	.	.	.
cord-312486-rumqopg0	279	1	Actually	actually	RB
cord-312486-rumqopg0	279	2	,	,	,
cord-312486-rumqopg0	279	3	the	the	DT
cord-312486-rumqopg0	279	4	TCR	TCR	NNP
cord-312486-rumqopg0	279	5	contacts	contact	NNS
cord-312486-rumqopg0	279	6	only	only	RB
cord-312486-rumqopg0	279	7	2	2	CD
cord-312486-rumqopg0	279	8	-	-	SYM
cord-312486-rumqopg0	279	9	4	4	CD
cord-312486-rumqopg0	279	10	amino	amino	JJ
cord-312486-rumqopg0	279	11	acids	acid	NNS
cord-312486-rumqopg0	279	12	in	in	IN
cord-312486-rumqopg0	279	13	the	the	DT
cord-312486-rumqopg0	279	14	peptide	peptide	NN
cord-312486-rumqopg0	279	15	,	,	,
cord-312486-rumqopg0	279	16	so	so	RB
cord-312486-rumqopg0	280	1	the	the	DT
cord-312486-rumqopg0	280	2	total	total	JJ
cord-312486-rumqopg0	280	3	energy	energy	NN
cord-312486-rumqopg0	280	4	of	of	IN
cord-312486-rumqopg0	280	5	the	the	DT
cord-312486-rumqopg0	280	6	TCR	TCR	NNP
cord-312486-rumqopg0	280	7	-	-	HYPH
cord-312486-rumqopg0	280	8	peptide	peptide	NN
cord-312486-rumqopg0	280	9	-	-	HYPH
cord-312486-rumqopg0	280	10	HLA	hla	NN
cord-312486-rumqopg0	280	11	interaction	interaction	NN
cord-312486-rumqopg0	280	12	is	be	VBZ
cord-312486-rumqopg0	280	13	heavily	heavily	RB
cord-312486-rumqopg0	280	14	influenced	influence	VBN
cord-312486-rumqopg0	280	15	by	by	IN
cord-312486-rumqopg0	280	16	the	the	DT
cord-312486-rumqopg0	280	17	HLA	HLA	NNP
cord-312486-rumqopg0	280	18	rather	rather	RB
cord-312486-rumqopg0	280	19	than	than	IN
cord-312486-rumqopg0	280	20	the	the	DT
cord-312486-rumqopg0	280	21	peptide	peptide	NN
cord-312486-rumqopg0	280	22	.	.	.
cord-312486-rumqopg0	281	1	The	the	DT
cord-312486-rumqopg0	281	2	consequence	consequence	NN
cord-312486-rumqopg0	281	3	is	be	VBZ
cord-312486-rumqopg0	281	4	a	a	DT
cord-312486-rumqopg0	281	5	highly	highly	RB
cord-312486-rumqopg0	281	6	promiscuous	promiscuous	JJ
cord-312486-rumqopg0	281	7	T	t	NN
cord-312486-rumqopg0	281	8	cell	cell	NN
cord-312486-rumqopg0	281	9	which	which	WDT
cord-312486-rumqopg0	281	10	allows	allow	VBZ
cord-312486-rumqopg0	281	11	a	a	DT
cord-312486-rumqopg0	281	12	large	large	JJ
cord-312486-rumqopg0	281	13	variation	variation	NN
cord-312486-rumqopg0	281	14	in	in	IN
cord-312486-rumqopg0	281	15	peptide	peptide	NN
cord-312486-rumqopg0	281	16	sequences	sequence	NNS
cord-312486-rumqopg0	281	17	without	without	IN
cord-312486-rumqopg0	281	18	inhibiting	inhibit	VBG
cord-312486-rumqopg0	281	19	the	the	DT
cord-312486-rumqopg0	281	20	HLA	HLA	NNP
cord-312486-rumqopg0	281	21	-	-	HYPH
cord-312486-rumqopg0	281	22	peptide	peptide	NN
cord-312486-rumqopg0	281	23	-	-	HYPH
cord-312486-rumqopg0	281	24	TCR	TCR	NNP
cord-312486-rumqopg0	281	25	interaction	interaction	NN
cord-312486-rumqopg0	281	26	[	[	-LRB-
cord-312486-rumqopg0	281	27	132	132	CD
cord-312486-rumqopg0	281	28	]	]	-RRB-
cord-312486-rumqopg0	281	29	.	.	.
cord-312486-rumqopg0	282	1	Hosts	host	NNS
cord-312486-rumqopg0	282	2	that	that	WDT
cord-312486-rumqopg0	282	3	have	have	VBP
cord-312486-rumqopg0	282	4	never	never	RB
cord-312486-rumqopg0	282	5	experienced	experience	VBN
cord-312486-rumqopg0	282	6	a	a	DT
cord-312486-rumqopg0	282	7	particular	particular	JJ
cord-312486-rumqopg0	282	8	virus	virus	NN
cord-312486-rumqopg0	282	9	,	,	,
cord-312486-rumqopg0	282	10	might	may	MD
cord-312486-rumqopg0	282	11	,	,	,
cord-312486-rumqopg0	282	12	nevertheless	nevertheless	RB
cord-312486-rumqopg0	282	13	,	,	,
cord-312486-rumqopg0	282	14	have	have	VBP
cord-312486-rumqopg0	282	15	memory	memory	NN
cord-312486-rumqopg0	282	16	T	t	NN
cord-312486-rumqopg0	282	17	cell	cell	NN
cord-312486-rumqopg0	282	18	pools	pool	NNS
cord-312486-rumqopg0	282	19	that	that	WDT
cord-312486-rumqopg0	282	20	show	show	VBP
cord-312486-rumqopg0	282	21	specificity	specificity	NN
cord-312486-rumqopg0	282	22	for	for	IN
cord-312486-rumqopg0	282	23	it	-PRON-	PRP
cord-312486-rumqopg0	282	24	by	by	IN
cord-312486-rumqopg0	282	25	virtue	virtue	NN
cord-312486-rumqopg0	282	26	of	of	IN
cord-312486-rumqopg0	282	27	crossreactivity	crossreactivity	NN
cord-312486-rumqopg0	282	28	that	that	WDT
cord-312486-rumqopg0	282	29	can	can	MD
cord-312486-rumqopg0	282	30	shape	shape	VB
cord-312486-rumqopg0	282	31	the	the	DT
cord-312486-rumqopg0	282	32	repertoire	repertoire	NN
cord-312486-rumqopg0	282	33	of	of	IN
cord-312486-rumqopg0	282	34	the	the	DT
cord-312486-rumqopg0	282	35	primary	primary	JJ
cord-312486-rumqopg0	282	36	response	response	NN
cord-312486-rumqopg0	282	37	.	.	.
cord-312486-rumqopg0	283	1	The	the	DT
cord-312486-rumqopg0	283	2	observation	observation	NN
cord-312486-rumqopg0	283	3	that	that	IN
cord-312486-rumqopg0	283	4	the	the	DT
cord-312486-rumqopg0	283	5	same	same	JJ
cord-312486-rumqopg0	283	6	virus	virus	NN
cord-312486-rumqopg0	283	7	can	can	MD
cord-312486-rumqopg0	283	8	cause	cause	VB
cord-312486-rumqopg0	283	9	widely	widely	RB
cord-312486-rumqopg0	283	10	different	different	JJ
cord-312486-rumqopg0	283	11	pathological	pathological	JJ
cord-312486-rumqopg0	283	12	manifestations	manifestation	NNS
cord-312486-rumqopg0	283	13	in	in	IN
cord-312486-rumqopg0	283	14	humans	human	NNS
cord-312486-rumqopg0	283	15	might	may	MD
cord-312486-rumqopg0	283	16	be	be	VB
cord-312486-rumqopg0	283	17	due	due	JJ
cord-312486-rumqopg0	283	18	(	(	-LRB-
cord-312486-rumqopg0	283	19	at	at	IN
cord-312486-rumqopg0	283	20	least	least	JJS
cord-312486-rumqopg0	283	21	in	in	IN
cord-312486-rumqopg0	283	22	part	part	NN
cord-312486-rumqopg0	283	23	)	)	-RRB-
cord-312486-rumqopg0	283	24	to	to	IN
cord-312486-rumqopg0	283	25	an	an	DT
cord-312486-rumqopg0	283	26	established	establish	VBN
cord-312486-rumqopg0	283	27	adaptive	adaptive	JJ
cord-312486-rumqopg0	283	28	immunity	immunity	NN
cord-312486-rumqopg0	283	29	toward	toward	IN
cord-312486-rumqopg0	283	30	related	related	JJ
cord-312486-rumqopg0	283	31	or	or	CC
cord-312486-rumqopg0	283	32	unrelated	unrelated	JJ
cord-312486-rumqopg0	283	33	viruses	virus	NNS
cord-312486-rumqopg0	283	34	,	,	,
cord-312486-rumqopg0	283	35	which	which	WDT
cord-312486-rumqopg0	283	36	results	result	VBZ
cord-312486-rumqopg0	283	37	in	in	IN
cord-312486-rumqopg0	283	38	enhanced	enhanced	JJ
cord-312486-rumqopg0	283	39	protective	protective	JJ
cord-312486-rumqopg0	283	40	immunity	immunity	NN
cord-312486-rumqopg0	283	41	in	in	IN
cord-312486-rumqopg0	283	42	some	some	DT
cord-312486-rumqopg0	283	43	,	,	,
cord-312486-rumqopg0	283	44	reduced	reduce	VBN
cord-312486-rumqopg0	283	45	protective	protective	JJ
cord-312486-rumqopg0	283	46	immunity	immunity	NN
cord-312486-rumqopg0	283	47	in	in	IN
cord-312486-rumqopg0	283	48	others	other	NNS
cord-312486-rumqopg0	283	49	,	,	,
cord-312486-rumqopg0	283	50	or	or	CC
cord-312486-rumqopg0	283	51	altered	alter	VBN
cord-312486-rumqopg0	283	52	immunopathology	immunopathology	NN
cord-312486-rumqopg0	283	53	,	,	,
cord-312486-rumqopg0	283	54	including	include	VBG
cord-312486-rumqopg0	283	55	enhanced	enhance	VBN
cord-312486-rumqopg0	283	56	disease	disease	NN
cord-312486-rumqopg0	283	57	severity	severity	NN
cord-312486-rumqopg0	283	58	in	in	IN
cord-312486-rumqopg0	283	59	some	some	DT
cord-312486-rumqopg0	283	60	hosts	host	NNS
cord-312486-rumqopg0	283	61	[	[	-LRB-
cord-312486-rumqopg0	283	62	133	133	CD
cord-312486-rumqopg0	283	63	]	]	-RRB-
cord-312486-rumqopg0	283	64	.	.	.
cord-312486-rumqopg0	284	1	The	the	DT
cord-312486-rumqopg0	284	2	role	role	NN
cord-312486-rumqopg0	284	3	of	of	IN
cord-312486-rumqopg0	284	4	humoral	humoral	JJ
cord-312486-rumqopg0	284	5	responses	response	NNS
cord-312486-rumqopg0	284	6	in	in	IN
cord-312486-rumqopg0	284	7	the	the	DT
cord-312486-rumqopg0	284	8	pathogenesis	pathogenesis	NN
cord-312486-rumqopg0	284	9	of	of	IN
cord-312486-rumqopg0	284	10	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	284	11	remains	remain	VBZ
cord-312486-rumqopg0	284	12	unclear	unclear	JJ
cord-312486-rumqopg0	284	13	.	.	.
cord-312486-rumqopg0	285	1	As	as	IN
cord-312486-rumqopg0	285	2	in	in	IN
cord-312486-rumqopg0	285	3	SARS	SARS	NNP
cord-312486-rumqopg0	285	4	-	-	HYPH
cord-312486-rumqopg0	285	5	CoV-1	CoV-1	NNP
cord-312486-rumqopg0	285	6	infection	infection	NN
cord-312486-rumqopg0	285	7	,	,	,
cord-312486-rumqopg0	285	8	most	most	JJS
cord-312486-rumqopg0	285	9	subjects	subject	NNS
cord-312486-rumqopg0	285	10	infected	infect	VBN
cord-312486-rumqopg0	285	11	by	by	IN
cord-312486-rumqopg0	285	12	SARS	SARS	NNP
cord-312486-rumqopg0	285	13	-	-	HYPH
cord-312486-rumqopg0	285	14	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	285	15	seroconvert	seroconvert	VB
cord-312486-rumqopg0	285	16	within	within	IN
cord-312486-rumqopg0	285	17	7	7	CD
cord-312486-rumqopg0	285	18	-	-	SYM
cord-312486-rumqopg0	285	19	14	14	CD
cord-312486-rumqopg0	285	20	days	day	NNS
cord-312486-rumqopg0	285	21	after	after	IN
cord-312486-rumqopg0	285	22	infection	infection	NN
cord-312486-rumqopg0	285	23	and	and	CC
cord-312486-rumqopg0	285	24	this	this	DT
cord-312486-rumqopg0	285	25	process	process	NN
cord-312486-rumqopg0	285	26	is	be	VBZ
cord-312486-rumqopg0	285	27	associated	associate	VBN
cord-312486-rumqopg0	285	28	with	with	IN
cord-312486-rumqopg0	285	29	increase	increase	NN
cord-312486-rumqopg0	285	30	in	in	IN
cord-312486-rumqopg0	285	31	plasma	plasma	NN
cord-312486-rumqopg0	285	32	cells	cell	NNS
cord-312486-rumqopg0	285	33	,	,	,
cord-312486-rumqopg0	285	34	whereas	whereas	IN
cord-312486-rumqopg0	285	35	naïve	naïve	JJ
cord-312486-rumqopg0	285	36	B	B	NNP
cord-312486-rumqopg0	285	37	cells	cell	NNS
cord-312486-rumqopg0	285	38	decrease	decrease	VBP
cord-312486-rumqopg0	285	39	significantly	significantly	RB
cord-312486-rumqopg0	285	40	[	[	-LRB-
cord-312486-rumqopg0	285	41	134	134	CD
cord-312486-rumqopg0	285	42	]	]	-RRB-
cord-312486-rumqopg0	285	43	.	.	.
cord-312486-rumqopg0	286	1	While	while	IN
cord-312486-rumqopg0	286	2	recovered	recover	VBN
cord-312486-rumqopg0	286	3	patients	patient	NNS
cord-312486-rumqopg0	286	4	generate	generate	VBP
cord-312486-rumqopg0	286	5	SARS	SARS	NNP
cord-312486-rumqopg0	286	6	-	-	HYPH
cord-312486-rumqopg0	286	7	CoV-2specific	CoV-2specific	NNP
cord-312486-rumqopg0	286	8	neutralizing	neutralize	VBG
cord-312486-rumqopg0	286	9	Abs	abs	NN
cord-312486-rumqopg0	286	10	and	and	CC
cord-312486-rumqopg0	286	11	spike	spike	NN
cord-312486-rumqopg0	286	12	-	-	HYPH
cord-312486-rumqopg0	286	13	binding	bind	VBG
cord-312486-rumqopg0	286	14	Abs	abs	NN
cord-312486-rumqopg0	287	1	concurrently	concurrently	RB
cord-312486-rumqopg0	287	2	,	,	,
cord-312486-rumqopg0	287	3	their	-PRON-	PRP$
cord-312486-rumqopg0	287	4	titers	titer	NNS
cord-312486-rumqopg0	287	5	are	be	VBP
cord-312486-rumqopg0	287	6	highly	highly	RB
cord-312486-rumqopg0	287	7	variable	variable	JJ
cord-312486-rumqopg0	287	8	in	in	IN
cord-312486-rumqopg0	287	9	different	different	JJ
cord-312486-rumqopg0	287	10	patients	patient	NNS
cord-312486-rumqopg0	287	11	[	[	-LRB-
cord-312486-rumqopg0	287	12	135	135	CD
cord-312486-rumqopg0	287	13	]	]	-RRB-
cord-312486-rumqopg0	287	14	.	.	.
cord-312486-rumqopg0	288	1	About	about	RB
cord-312486-rumqopg0	288	2	one	one	CD
cord-312486-rumqopg0	288	3	third	third	NN
cord-312486-rumqopg0	288	4	of	of	IN
cord-312486-rumqopg0	288	5	recovered	recover	VBN
cord-312486-rumqopg0	288	6	patients	patient	NNS
cord-312486-rumqopg0	288	7	generate	generate	VBP
cord-312486-rumqopg0	288	8	very	very	RB
cord-312486-rumqopg0	288	9	low	low	JJ
cord-312486-rumqopg0	288	10	titers	titer	NNS
cord-312486-rumqopg0	288	11	of	of	IN
cord-312486-rumqopg0	288	12	SARS	SARS	NNP
cord-312486-rumqopg0	288	13	-	-	HYPH
cord-312486-rumqopg0	288	14	CoV-2-specific	CoV-2-specific	NNP
cord-312486-rumqopg0	288	15	neutralizing	neutralize	VBG
cord-312486-rumqopg0	288	16	Abs	Abs	NNP
cord-312486-rumqopg0	288	17	[	[	-LRB-
cord-312486-rumqopg0	288	18	135	135	CD
cord-312486-rumqopg0	288	19	,	,	,
cord-312486-rumqopg0	288	20	136	136	CD
cord-312486-rumqopg0	288	21	]	]	-RRB-
cord-312486-rumqopg0	288	22	,	,	,
cord-312486-rumqopg0	288	23	and	and	CC
cord-312486-rumqopg0	289	1	some	some	DT
cord-312486-rumqopg0	289	2	patients	patient	NNS
cord-312486-rumqopg0	289	3	(	(	-LRB-
cord-312486-rumqopg0	289	4	possibly	possibly	RB
cord-312486-rumqopg0	289	5	up	up	IN
cord-312486-rumqopg0	289	6	to	to	TO
cord-312486-rumqopg0	289	7	20	20	CD
cord-312486-rumqopg0	289	8	%	%	NN
cord-312486-rumqopg0	289	9	)	)	-RRB-
cord-312486-rumqopg0	289	10	who	who	WP
cord-312486-rumqopg0	289	11	recover	recover	VBP
cord-312486-rumqopg0	289	12	,	,	,
cord-312486-rumqopg0	289	13	do	do	VBP
cord-312486-rumqopg0	289	14	not	not	RB
cord-312486-rumqopg0	289	15	have	have	VB
cord-312486-rumqopg0	289	16	detectable	detectable	JJ
cord-312486-rumqopg0	289	17	neutralizing	neutralize	VBG
cord-312486-rumqopg0	289	18	antibodies	antibody	NNS
cord-312486-rumqopg0	289	19	at	at	RB
cord-312486-rumqopg0	289	20	all	all	DT
cord-312486-rumqopg0	289	21	[	[	-LRB-
cord-312486-rumqopg0	289	22	129	129	CD
cord-312486-rumqopg0	289	23	,	,	,
cord-312486-rumqopg0	289	24	135	135	CD
cord-312486-rumqopg0	289	25	,	,	,
cord-312486-rumqopg0	289	26	137	137	CD
cord-312486-rumqopg0	289	27	]	]	-RRB-
cord-312486-rumqopg0	289	28	.	.	.
cord-312486-rumqopg0	290	1	These	these	DT
cord-312486-rumqopg0	290	2	observations	observation	NNS
cord-312486-rumqopg0	290	3	bring	bring	VBP
cord-312486-rumqopg0	290	4	up	up	RP
cord-312486-rumqopg0	290	5	the	the	DT
cord-312486-rumqopg0	290	6	question	question	NN
cord-312486-rumqopg0	290	7	of	of	IN
cord-312486-rumqopg0	290	8	how	how	WRB
cord-312486-rumqopg0	290	9	the	the	DT
cord-312486-rumqopg0	290	10	virus	virus	NN
cord-312486-rumqopg0	290	11	was	be	VBD
cord-312486-rumqopg0	290	12	cleared	clear	VBN
cord-312486-rumqopg0	290	13	-	-	:
cord-312486-rumqopg0	290	14	as	as	IN
cord-312486-rumqopg0	290	15	it	-PRON-	PRP
cord-312486-rumqopg0	290	16	eventually	eventually	RB
cord-312486-rumqopg0	290	17	was	be	VBD
cord-312486-rumqopg0	290	18	in	in	IN
cord-312486-rumqopg0	290	19	all	all	PDT
cord-312486-rumqopg0	290	20	those	those	DT
cord-312486-rumqopg0	290	21	patients	patient	NNS
cord-312486-rumqopg0	290	22	studied	study	VBN
cord-312486-rumqopg0	290	23	-	-	:
cord-312486-rumqopg0	290	24	without	without	IN
cord-312486-rumqopg0	290	25	strong	strong	JJ
cord-312486-rumqopg0	290	26	Ab	Ab	NNP
cord-312486-rumqopg0	290	27	responses	response	NNS
cord-312486-rumqopg0	290	28	.	.	.
cord-312486-rumqopg0	291	1	We	-PRON-	PRP
cord-312486-rumqopg0	291	2	can	can	MD
cord-312486-rumqopg0	291	3	speculate	speculate	VB
cord-312486-rumqopg0	291	4	that	that	IN
cord-312486-rumqopg0	291	5	T	t	NN
cord-312486-rumqopg0	291	6	-	-	HYPH
cord-312486-rumqopg0	291	7	cell	cell	NN
cord-312486-rumqopg0	291	8	mediated	mediate	VBN
cord-312486-rumqopg0	291	9	immune	immune	JJ
cord-312486-rumqopg0	291	10	responses	response	NNS
cord-312486-rumqopg0	291	11	,	,	,
cord-312486-rumqopg0	291	12	or	or	CC
cord-312486-rumqopg0	291	13	non	non	JJ
cord-312486-rumqopg0	291	14	-	-	JJ
cord-312486-rumqopg0	291	15	specific	specific	JJ
cord-312486-rumqopg0	291	16	responses	response	NNS
cord-312486-rumqopg0	291	17	by	by	IN
cord-312486-rumqopg0	291	18	innate	innate	JJ
cord-312486-rumqopg0	291	19	immune	immune	JJ
cord-312486-rumqopg0	291	20	cells	cell	NNS
cord-312486-rumqopg0	291	21	were	be	VBD
cord-312486-rumqopg0	291	22	responsible	responsible	JJ
cord-312486-rumqopg0	291	23	for	for	IN
cord-312486-rumqopg0	291	24	viral	viral	JJ
cord-312486-rumqopg0	291	25	clearance	clearance	NN
cord-312486-rumqopg0	291	26	.	.	.
cord-312486-rumqopg0	292	1	However	however	RB
cord-312486-rumqopg0	292	2	,	,	,
cord-312486-rumqopg0	292	3	since	since	IN
cord-312486-rumqopg0	292	4	a	a	DT
cord-312486-rumqopg0	292	5	pathogen	pathogen	NN
cord-312486-rumqopg0	292	6	that	that	WDT
cord-312486-rumqopg0	292	7	kills	kill	VBZ
cord-312486-rumqopg0	292	8	off	off	IN
cord-312486-rumqopg0	292	9	the	the	DT
cord-312486-rumqopg0	292	10	host	host	NN
cord-312486-rumqopg0	292	11	that	that	IN
cord-312486-rumqopg0	292	12	it	-PRON-	PRP
cord-312486-rumqopg0	292	13	needs	need	VBZ
cord-312486-rumqopg0	292	14	to	to	TO
cord-312486-rumqopg0	292	15	survive	survive	VB
cord-312486-rumqopg0	292	16	is	be	VBZ
cord-312486-rumqopg0	292	17	also	also	RB
cord-312486-rumqopg0	292	18	threatening	threaten	VBG
cord-312486-rumqopg0	292	19	its	-PRON-	PRP$
cord-312486-rumqopg0	292	20	very	very	RB
cord-312486-rumqopg0	292	21	own	own	JJ
cord-312486-rumqopg0	292	22	existence	existence	NN
cord-312486-rumqopg0	292	23	,	,	,
cord-312486-rumqopg0	292	24	the	the	DT
cord-312486-rumqopg0	292	25	possibility	possibility	NN
cord-312486-rumqopg0	292	26	of	of	IN
cord-312486-rumqopg0	292	27	CoV	CoV	NNP
cord-312486-rumqopg0	292	28	self	self	NN
cord-312486-rumqopg0	292	29	-	-	HYPH
cord-312486-rumqopg0	292	30	clearing	clearing	NN
cord-312486-rumqopg0	292	31	should	should	MD
cord-312486-rumqopg0	292	32	be	be	VB
cord-312486-rumqopg0	292	33	considered	consider	VBN
cord-312486-rumqopg0	292	34	,	,	,
cord-312486-rumqopg0	292	35	especially	especially	RB
cord-312486-rumqopg0	292	36	when	when	WRB
cord-312486-rumqopg0	292	37	alternative	alternative	JJ
cord-312486-rumqopg0	292	38	hosts	host	NNS
cord-312486-rumqopg0	292	39	are	be	VBP
cord-312486-rumqopg0	292	40	plentiful	plentiful	JJ
cord-312486-rumqopg0	292	41	.	.	.
cord-312486-rumqopg0	293	1	In	in	IN
cord-312486-rumqopg0	293	2	a	a	DT
cord-312486-rumqopg0	293	3	remarkable	remarkable	JJ
cord-312486-rumqopg0	293	4	study	study	NN
cord-312486-rumqopg0	293	5	[	[	-LRB-
cord-312486-rumqopg0	293	6	137	137	CD
cord-312486-rumqopg0	293	7	]	]	-RRB-
cord-312486-rumqopg0	293	8	the	the	DT
cord-312486-rumqopg0	293	9	levels	level	NNS
cord-312486-rumqopg0	293	10	of	of	IN
cord-312486-rumqopg0	293	11	total	total	JJ
cord-312486-rumqopg0	293	12	IgG	igg	NN
cord-312486-rumqopg0	293	13	and	and	CC
cord-312486-rumqopg0	293	14	IgG	IgG	NNP
cord-312486-rumqopg0	293	15	neutralizing	neutralize	VBG
cord-312486-rumqopg0	293	16	antibodies	antibody	NNS
cord-312486-rumqopg0	293	17	(	(	-LRB-
cord-312486-rumqopg0	293	18	as	as	IN
cord-312486-rumqopg0	293	19	measured	measure	VBN
cord-312486-rumqopg0	293	20	using	use	VBG
cord-312486-rumqopg0	293	21	a	a	DT
cord-312486-rumqopg0	293	22	spike	spike	NN
cord-312486-rumqopg0	293	23	protein	protein	NN
cord-312486-rumqopg0	293	24	pseudotyped	pseudotyped	NNP
cord-312486-rumqopg0	293	25	virus	virus	NN
cord-312486-rumqopg0	293	26	)	)	-RRB-
cord-312486-rumqopg0	293	27	were	be	VBD
cord-312486-rumqopg0	293	28	quantified	quantify	VBN
cord-312486-rumqopg0	293	29	in	in	IN
cord-312486-rumqopg0	293	30	symptomatic	symptomatic	JJ
cord-312486-rumqopg0	293	31	and	and	CC
cord-312486-rumqopg0	293	32	asymptomatic	asymptomatic	JJ
cord-312486-rumqopg0	293	33	patients	patient	NNS
cord-312486-rumqopg0	293	34	eight	eight	CD
cord-312486-rumqopg0	293	35	weeks	week	NNS
cord-312486-rumqopg0	293	36	after	after	IN
cord-312486-rumqopg0	293	37	release	release	NN
cord-312486-rumqopg0	293	38	from	from	IN
cord-312486-rumqopg0	293	39	the	the	DT
cord-312486-rumqopg0	293	40	hospital	hospital	NN
cord-312486-rumqopg0	293	41	(	(	-LRB-
cord-312486-rumqopg0	293	42	roughly	roughly	RB
cord-312486-rumqopg0	293	43	three	three	CD
cord-312486-rumqopg0	293	44	months	month	NNS
cord-312486-rumqopg0	293	45	after	after	IN
cord-312486-rumqopg0	293	46	start	start	NN
cord-312486-rumqopg0	293	47	of	of	IN
cord-312486-rumqopg0	293	48	infection	infection	NN
cord-312486-rumqopg0	293	49	)	)	-RRB-
cord-312486-rumqopg0	293	50	.	.	.
cord-312486-rumqopg0	294	1	The	the	DT
cord-312486-rumqopg0	294	2	levels	level	NNS
cord-312486-rumqopg0	294	3	of	of	IN
cord-312486-rumqopg0	294	4	IgG	igg	NN
cord-312486-rumqopg0	294	5	and	and	CC
cord-312486-rumqopg0	294	6	neutralizing	neutralize	VBG
cord-312486-rumqopg0	294	7	antibodies	antibody	NNS
cord-312486-rumqopg0	294	8	were	be	VBD
cord-312486-rumqopg0	294	9	significantly	significantly	RB
cord-312486-rumqopg0	294	10	decreased	decrease	VBN
cord-312486-rumqopg0	294	11	in	in	IN
cord-312486-rumqopg0	294	12	the	the	DT
cord-312486-rumqopg0	294	13	majority	majority	NN
cord-312486-rumqopg0	294	14	of	of	IN
cord-312486-rumqopg0	294	15	patients	patient	NNS
cord-312486-rumqopg0	294	16	in	in	IN
cord-312486-rumqopg0	294	17	both	both	DT
cord-312486-rumqopg0	294	18	groups	group	NNS
cord-312486-rumqopg0	294	19	.	.	.
cord-312486-rumqopg0	295	1	The	the	DT
cord-312486-rumqopg0	295	2	decrease	decrease	NN
cord-312486-rumqopg0	295	3	in	in	IN
cord-312486-rumqopg0	295	4	neutralizing	neutralize	VBG
cord-312486-rumqopg0	295	5	Abs	Abs	NNP
cord-312486-rumqopg0	295	6	was	be	VBD
cord-312486-rumqopg0	295	7	more	more	RBR
cord-312486-rumqopg0	295	8	pronounced	pronounced	JJ
cord-312486-rumqopg0	295	9	in	in	IN
cord-312486-rumqopg0	295	10	asymptomatic	asymptomatic	JJ
cord-312486-rumqopg0	295	11	(	(	-LRB-
cord-312486-rumqopg0	295	12	~80	~80	NFP
cord-312486-rumqopg0	295	13	%	%	NN
cord-312486-rumqopg0	295	14	)	)	-RRB-
cord-312486-rumqopg0	295	15	as	as	IN
cord-312486-rumqopg0	295	16	compared	compare	VBN
cord-312486-rumqopg0	295	17	to	to	IN
cord-312486-rumqopg0	295	18	symptomatic	symptomatic	JJ
cord-312486-rumqopg0	295	19	(	(	-LRB-
cord-312486-rumqopg0	295	20	~60	~60	CD
cord-312486-rumqopg0	295	21	%	%	NN
cord-312486-rumqopg0	295	22	)	)	-RRB-
cord-312486-rumqopg0	295	23	patients	patient	NNS
cord-312486-rumqopg0	295	24	.	.	.
cord-312486-rumqopg0	296	1	Taken	take	VBN
cord-312486-rumqopg0	296	2	together	together	RB
cord-312486-rumqopg0	296	3	,	,	,
cord-312486-rumqopg0	296	4	the	the	DT
cord-312486-rumqopg0	296	5	finding	finding	NN
cord-312486-rumqopg0	296	6	that	that	WDT
cord-312486-rumqopg0	296	7	~20	~20	NFP
cord-312486-rumqopg0	296	8	%	%	NN
cord-312486-rumqopg0	296	9	of	of	IN
cord-312486-rumqopg0	296	10	people	people	NNS
cord-312486-rumqopg0	296	11	infected	infect	VBN
cord-312486-rumqopg0	296	12	with	with	IN
cord-312486-rumqopg0	296	13	SARS	SARS	NNP
cord-312486-rumqopg0	296	14	-	-	HYPH
cord-312486-rumqopg0	296	15	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	296	16	do	do	VBP
cord-312486-rumqopg0	296	17	not	not	RB
cord-312486-rumqopg0	296	18	make	make	VB
cord-312486-rumqopg0	296	19	anti	anti	JJ
cord-312486-rumqopg0	296	20	-	-	JJ
cord-312486-rumqopg0	296	21	viral	viral	JJ
cord-312486-rumqopg0	296	22	Abs	abs	NN
cord-312486-rumqopg0	296	23	,	,	,
cord-312486-rumqopg0	296	24	added	add	VBD
cord-312486-rumqopg0	296	25	to	to	IN
cord-312486-rumqopg0	296	26	the	the	DT
cord-312486-rumqopg0	296	27	observation	observation	NN
cord-312486-rumqopg0	296	28	that	that	IN
cord-312486-rumqopg0	296	29	neutralizing	neutralize	VBG
cord-312486-rumqopg0	296	30	Abs	Abs	NNP
cord-312486-rumqopg0	296	31	begin	begin	VB
cord-312486-rumqopg0	296	32	to	to	TO
cord-312486-rumqopg0	296	33	drop	drop	VB
cord-312486-rumqopg0	296	34	noticeably	noticeably	RB
cord-312486-rumqopg0	296	35	during	during	IN
cord-312486-rumqopg0	296	36	convalescence	convalescence	NN
cord-312486-rumqopg0	296	37	-	-	,
cord-312486-rumqopg0	296	38	suggests	suggest	VBZ
cord-312486-rumqopg0	296	39	that	that	IN
cord-312486-rumqopg0	296	40	infection	infection	NN
cord-312486-rumqopg0	296	41	with	with	IN
cord-312486-rumqopg0	296	42	SARS	SARS	NNP
cord-312486-rumqopg0	296	43	-	-	HYPH
cord-312486-rumqopg0	296	44	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	296	45	does	do	VBZ
cord-312486-rumqopg0	296	46	not	not	RB
cord-312486-rumqopg0	296	47	establish	establish	VB
cord-312486-rumqopg0	296	48	long	long	RB
cord-312486-rumqopg0	296	49	-	-	HYPH
cord-312486-rumqopg0	296	50	lasting	last	VBG
cord-312486-rumqopg0	296	51	serological	serological	JJ
cord-312486-rumqopg0	296	52	immunity	immunity	NN
cord-312486-rumqopg0	296	53	,	,	,
cord-312486-rumqopg0	296	54	at	at	IN
cord-312486-rumqopg0	296	55	least	least	JJS
cord-312486-rumqopg0	296	56	not	not	RB
cord-312486-rumqopg0	296	57	for	for	IN
cord-312486-rumqopg0	296	58	those	those	DT
cord-312486-rumqopg0	296	59	who	who	WP
cord-312486-rumqopg0	296	60	are	be	VBP
cord-312486-rumqopg0	296	61	asymptomatic	asymptomatic	JJ
cord-312486-rumqopg0	296	62	or	or	CC
cord-312486-rumqopg0	296	63	mildly	mildly	RB
cord-312486-rumqopg0	296	64	ill	ill	JJ
cord-312486-rumqopg0	296	65	(	(	-LRB-
cord-312486-rumqopg0	296	66	more	more	JJR
cord-312486-rumqopg0	296	67	than	than	IN
cord-312486-rumqopg0	296	68	80	80	CD
cord-312486-rumqopg0	296	69	%	%	NN
cord-312486-rumqopg0	296	70	of	of	IN
cord-312486-rumqopg0	296	71	all	all	PDT
cord-312486-rumqopg0	296	72	those	those	DT
cord-312486-rumqopg0	296	73	infected	infect	VBN
cord-312486-rumqopg0	296	74	by	by	IN
cord-312486-rumqopg0	296	75	SARS	SARS	NNP
cord-312486-rumqopg0	296	76	-	-	HYPH
cord-312486-rumqopg0	296	77	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	296	78	)	)	-RRB-
cord-312486-rumqopg0	296	79	.	.	.
cord-312486-rumqopg0	297	1	Even	even	RB
cord-312486-rumqopg0	297	2	more	more	RBR
cord-312486-rumqopg0	297	3	problematic	problematic	JJ
cord-312486-rumqopg0	297	4	-	-	HYPH
cord-312486-rumqopg0	297	5	several	several	JJ
cord-312486-rumqopg0	297	6	studies	study	NNS
cord-312486-rumqopg0	297	7	show	show	VBP
cord-312486-rumqopg0	297	8	significantly	significantly	RB
cord-312486-rumqopg0	297	9	higher	high	JJR
cord-312486-rumqopg0	297	10	IgG	IgG	NNP
cord-312486-rumqopg0	297	11	and	and	CC
cord-312486-rumqopg0	297	12	IgA	IgA	NNP
cord-312486-rumqopg0	297	13	Ab	Ab	NNP
cord-312486-rumqopg0	297	14	responses	response	NNS
cord-312486-rumqopg0	297	15	.	.	.
cord-312486-rumqopg0	298	1	This	this	DT
cord-312486-rumqopg0	298	2	does	do	VBZ
cord-312486-rumqopg0	298	3	not	not	RB
cord-312486-rumqopg0	298	4	correlate	correlate	VB
cord-312486-rumqopg0	298	5	significantly	significantly	RB
cord-312486-rumqopg0	298	6	with	with	IN
cord-312486-rumqopg0	298	7	protection	protection	NN
cord-312486-rumqopg0	298	8	,	,	,
cord-312486-rumqopg0	298	9	but	but	CC
cord-312486-rumqopg0	298	10	rather	rather	RB
cord-312486-rumqopg0	298	11	with	with	IN
cord-312486-rumqopg0	298	12	severity	severity	NN
cord-312486-rumqopg0	298	13	of	of	IN
cord-312486-rumqopg0	298	14	disease	disease	NN
cord-312486-rumqopg0	298	15	[	[	-LRB-
cord-312486-rumqopg0	298	16	138	138	CD
cord-312486-rumqopg0	298	17	]	]	-RRB-
cord-312486-rumqopg0	298	18	[	[	-LRB-
cord-312486-rumqopg0	298	19	139	139	CD
cord-312486-rumqopg0	298	20	]	]	-RRB-
cord-312486-rumqopg0	298	21	[	[	-LRB-
cord-312486-rumqopg0	298	22	140	140	CD
cord-312486-rumqopg0	298	23	]	]	-RRB-
cord-312486-rumqopg0	298	24	[	[	-LRB-
cord-312486-rumqopg0	298	25	141	141	CD
cord-312486-rumqopg0	298	26	]	]	-RRB-
cord-312486-rumqopg0	298	27	similar	similar	JJ
cord-312486-rumqopg0	298	28	to	to	IN
cord-312486-rumqopg0	298	29	what	what	WP
cord-312486-rumqopg0	298	30	was	be	VBD
cord-312486-rumqopg0	298	31	seen	see	VBN
cord-312486-rumqopg0	298	32	in	in	IN
cord-312486-rumqopg0	298	33	SARS	SARS	NNP
cord-312486-rumqopg0	298	34	[	[	-LRB-
cord-312486-rumqopg0	298	35	142	142	CD
cord-312486-rumqopg0	298	36	]	]	-RRB-
cord-312486-rumqopg0	298	37	.	.	.
cord-312486-rumqopg0	299	1	At	at	IN
cord-312486-rumqopg0	299	2	minimum	minimum	NN
cord-312486-rumqopg0	299	3	,	,	,
cord-312486-rumqopg0	299	4	these	these	DT
cord-312486-rumqopg0	299	5	studies	study	NNS
cord-312486-rumqopg0	299	6	suggest	suggest	VBP
cord-312486-rumqopg0	299	7	that	that	IN
cord-312486-rumqopg0	299	8	a	a	DT
cord-312486-rumqopg0	299	9	robust	robust	JJ
cord-312486-rumqopg0	299	10	Ab	Ab	NNP
cord-312486-rumqopg0	299	11	response	response	NN
cord-312486-rumqopg0	299	12	is	be	VBZ
cord-312486-rumqopg0	299	13	insufficient	insufficient	JJ
cord-312486-rumqopg0	299	14	to	to	TO
cord-312486-rumqopg0	299	15	protect	protect	VB
cord-312486-rumqopg0	299	16	from	from	IN
cord-312486-rumqopg0	299	17	severe	severe	JJ
cord-312486-rumqopg0	299	18	disease	disease	NN
cord-312486-rumqopg0	299	19	[	[	-LRB-
cord-312486-rumqopg0	299	20	76	76	CD
cord-312486-rumqopg0	299	21	]	]	-RRB-
cord-312486-rumqopg0	299	22	.	.	.
cord-312486-rumqopg0	300	1	While	while	IN
cord-312486-rumqopg0	300	2	it	-PRON-	PRP
cord-312486-rumqopg0	300	3	is	be	VBZ
cord-312486-rumqopg0	300	4	frequently	frequently	RB
cord-312486-rumqopg0	300	5	assumed	assume	VBN
cord-312486-rumqopg0	300	6	that	that	IN
cord-312486-rumqopg0	300	7	anti	anti	JJ
cord-312486-rumqopg0	300	8	-	-	JJ
cord-312486-rumqopg0	300	9	SARS	SARS	NNP
cord-312486-rumqopg0	300	10	-	-	HYPH
cord-312486-rumqopg0	300	11	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	300	12	Abs	Abs	NNP
cord-312486-rumqopg0	300	13	might	may	MD
cord-312486-rumqopg0	300	14	be	be	VB
cord-312486-rumqopg0	300	15	either	either	CC
cord-312486-rumqopg0	300	16	beneficial	beneficial	JJ
cord-312486-rumqopg0	300	17	or	or	CC
cord-312486-rumqopg0	300	18	irrelevant	irrelevant	JJ
cord-312486-rumqopg0	300	19	,	,	,
cord-312486-rumqopg0	300	20	there	there	EX
cord-312486-rumqopg0	300	21	is	be	VBZ
cord-312486-rumqopg0	300	22	also	also	RB
cord-312486-rumqopg0	300	23	the	the	DT
cord-312486-rumqopg0	300	24	possibility	possibility	NN
cord-312486-rumqopg0	300	25	that	that	IN
cord-312486-rumqopg0	300	26	such	such	JJ
cord-312486-rumqopg0	300	27	Abs	Abs	NNP
cord-312486-rumqopg0	300	28	might	may	MD
cord-312486-rumqopg0	300	29	actually	actually	RB
cord-312486-rumqopg0	300	30	be	be	VB
cord-312486-rumqopg0	300	31	detrimental	detrimental	JJ
cord-312486-rumqopg0	300	32	.	.	.
cord-312486-rumqopg0	301	1	First	first	RB
cord-312486-rumqopg0	301	2	,	,	,
cord-312486-rumqopg0	301	3	Abs	Abs	NNP
cord-312486-rumqopg0	301	4	can	can	MD
cord-312486-rumqopg0	301	5	cause	cause	VB
cord-312486-rumqopg0	301	6	immunopathology	immunopathology	NN
cord-312486-rumqopg0	301	7	by	by	IN
cord-312486-rumqopg0	301	8	binding	bind	VBG
cord-312486-rumqopg0	301	9	viral	viral	JJ
cord-312486-rumqopg0	301	10	fragments	fragment	NNS
cord-312486-rumqopg0	301	11	followed	follow	VBN
cord-312486-rumqopg0	301	12	by	by	IN
cord-312486-rumqopg0	301	13	activation	activation	NN
cord-312486-rumqopg0	301	14	of	of	IN
cord-312486-rumqopg0	301	15	the	the	DT
cord-312486-rumqopg0	301	16	complement	complement	NN
cord-312486-rumqopg0	301	17	cascade	cascade	NN
cord-312486-rumqopg0	301	18	by	by	IN
cord-312486-rumqopg0	301	19	the	the	DT
cord-312486-rumqopg0	301	20	Ab	Ab	NNP
cord-312486-rumqopg0	301	21	complex	complex	NN
cord-312486-rumqopg0	301	22	.	.	.
cord-312486-rumqopg0	302	1	The	the	DT
cord-312486-rumqopg0	302	2	consequences	consequence	NNS
cord-312486-rumqopg0	302	3	of	of	IN
cord-312486-rumqopg0	302	4	complement	complement	JJ
cord-312486-rumqopg0	302	5	activation	activation	NN
cord-312486-rumqopg0	302	6	in	in	IN
cord-312486-rumqopg0	302	7	the	the	DT
cord-312486-rumqopg0	302	8	pathogenesis	pathogenesis	NN
cord-312486-rumqopg0	302	9	of	of	IN
cord-312486-rumqopg0	302	10	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	302	11	was	be	VBD
cord-312486-rumqopg0	302	12	discussed	discuss	VBN
cord-312486-rumqopg0	302	13	above	above	IN
cord-312486-rumqopg0	302	14	(	(	-LRB-
cord-312486-rumqopg0	302	15	section	section	NN
cord-312486-rumqopg0	302	16	4	4	CD
cord-312486-rumqopg0	302	17	)	)	-RRB-
cord-312486-rumqopg0	302	18	,	,	,
cord-312486-rumqopg0	302	19	and	and	CC
cord-312486-rumqopg0	302	20	extensively	extensively	RB
cord-312486-rumqopg0	302	21	reviewed	review	VBN
cord-312486-rumqopg0	302	22	by	by	IN
cord-312486-rumqopg0	302	23	others	other	NNS
cord-312486-rumqopg0	302	24	[	[	-LRB-
cord-312486-rumqopg0	302	25	91	91	CD
cord-312486-rumqopg0	302	26	]	]	-RRB-
cord-312486-rumqopg0	302	27	.	.	.
cord-312486-rumqopg0	303	1	Second	second	RB
cord-312486-rumqopg0	303	2	,	,	,
cord-312486-rumqopg0	303	3	Ab	Ab	NNP
cord-312486-rumqopg0	303	4	responses	response	NNS
cord-312486-rumqopg0	303	5	to	to	IN
cord-312486-rumqopg0	303	6	CoV	CoV	NNP
cord-312486-rumqopg0	303	7	may	may	MD
cord-312486-rumqopg0	303	8	contribute	contribute	VB
cord-312486-rumqopg0	303	9	to	to	IN
cord-312486-rumqopg0	303	10	pathology	pathology	NN
cord-312486-rumqopg0	303	11	via	via	IN
cord-312486-rumqopg0	303	12	Ab	ab	NN
cord-312486-rumqopg0	303	13	-	-	HYPH
cord-312486-rumqopg0	303	14	dependent	dependent	JJ
cord-312486-rumqopg0	303	15	enhancement	enhancement	NN
cord-312486-rumqopg0	303	16	(	(	-LRB-
cord-312486-rumqopg0	303	17	ADE	ADE	NNP
cord-312486-rumqopg0	303	18	)	)	-RRB-
cord-312486-rumqopg0	303	19	.	.	.
cord-312486-rumqopg0	304	1	ADE	ADE	NNP
cord-312486-rumqopg0	304	2	is	be	VBZ
cord-312486-rumqopg0	304	3	mediated	mediate	VBN
cord-312486-rumqopg0	304	4	by	by	IN
cord-312486-rumqopg0	304	5	non	non	JJ
cord-312486-rumqopg0	304	6	-	-	JJ
cord-312486-rumqopg0	304	7	neutralizing	neutralizing	JJ
cord-312486-rumqopg0	304	8	virus	virus	NN
cord-312486-rumqopg0	304	9	-	-	HYPH
cord-312486-rumqopg0	304	10	specific	specific	JJ
cord-312486-rumqopg0	304	11	IgG	igg	NN
cord-312486-rumqopg0	304	12	engagement	engagement	NN
cord-312486-rumqopg0	304	13	of	of	IN
cord-312486-rumqopg0	304	14	Fc	Fc	NNP
cord-312486-rumqopg0	304	15	-	-	HYPH
cord-312486-rumqopg0	304	16	receptors	receptor	NNS
cord-312486-rumqopg0	304	17	(	(	-LRB-
cord-312486-rumqopg0	304	18	FcR	FcR	NNP
cord-312486-rumqopg0	304	19	)	)	-RRB-
cord-312486-rumqopg0	304	20	expressed	express	VBN
cord-312486-rumqopg0	304	21	on	on	IN
cord-312486-rumqopg0	304	22	immune	immune	JJ
cord-312486-rumqopg0	304	23	cells	cell	NNS
cord-312486-rumqopg0	304	24	,	,	,
cord-312486-rumqopg0	304	25	particularly	particularly	RB
cord-312486-rumqopg0	304	26	monocytes	monocyte	NNS
cord-312486-rumqopg0	304	27	and	and	CC
cord-312486-rumqopg0	304	28	macrophages	macrophage	NNS
cord-312486-rumqopg0	304	29	,	,	,
cord-312486-rumqopg0	304	30	leading	lead	VBG
cord-312486-rumqopg0	304	31	to	to	IN
cord-312486-rumqopg0	304	32	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	304	33	activation	activation	NN
cord-312486-rumqopg0	304	34	of	of	IN
cord-312486-rumqopg0	304	35	these	these	DT
cord-312486-rumqopg0	304	36	cells	cell	NNS
cord-312486-rumqopg0	304	37	.	.	.
cord-312486-rumqopg0	305	1	Anti	Anti	NNP
cord-312486-rumqopg0	305	2	-	-	NNP
cord-312486-rumqopg0	305	3	S	S	NNP
cord-312486-rumqopg0	305	4	-	-	HYPH
cord-312486-rumqopg0	305	5	IgG	IgG	NNP
cord-312486-rumqopg0	305	6	passive	passive	JJ
cord-312486-rumqopg0	305	7	immunization	immunization	NN
cord-312486-rumqopg0	305	8	of	of	IN
cord-312486-rumqopg0	305	9	SARS	SARS	NNP
cord-312486-rumqopg0	305	10	-	-	HYPH
cord-312486-rumqopg0	305	11	CoV-1-infected	cov-1-infecte	VBN
cord-312486-rumqopg0	305	12	rhesus	rhesu	NNS
cord-312486-rumqopg0	305	13	monkeys	monkey	NNS
cord-312486-rumqopg0	305	14	significantly	significantly	RB
cord-312486-rumqopg0	305	15	enhanced	enhance	VBD
cord-312486-rumqopg0	305	16	the	the	DT
cord-312486-rumqopg0	305	17	viral	viral	JJ
cord-312486-rumqopg0	305	18	induced	induce	VBN
cord-312486-rumqopg0	305	19	acute	acute	JJ
cord-312486-rumqopg0	305	20	lung	lung	NN
cord-312486-rumqopg0	305	21	injury	injury	NN
cord-312486-rumqopg0	305	22	with	with	IN
cord-312486-rumqopg0	305	23	massive	massive	JJ
cord-312486-rumqopg0	305	24	accumulation	accumulation	NN
cord-312486-rumqopg0	305	25	of	of	IN
cord-312486-rumqopg0	305	26	monocytes	monocyte	NNS
cord-312486-rumqopg0	305	27	and	and	CC
cord-312486-rumqopg0	305	28	macrophages	macrophage	NNS
cord-312486-rumqopg0	305	29	in	in	IN
cord-312486-rumqopg0	305	30	the	the	DT
cord-312486-rumqopg0	305	31	lung	lung	NN
cord-312486-rumqopg0	305	32	in	in	IN
cord-312486-rumqopg0	305	33	an	an	DT
cord-312486-rumqopg0	305	34	FcγR	fcγr	JJ
cord-312486-rumqopg0	305	35	dependent	dependent	JJ
cord-312486-rumqopg0	305	36	fashion	fashion	NN
cord-312486-rumqopg0	305	37	[	[	-LRB-
cord-312486-rumqopg0	305	38	143	143	CD
cord-312486-rumqopg0	305	39	]	]	-RRB-
cord-312486-rumqopg0	305	40	.	.	.
cord-312486-rumqopg0	306	1	Further	further	RB
cord-312486-rumqopg0	306	2	,	,	,
cord-312486-rumqopg0	306	3	serum	serum	NN
cord-312486-rumqopg0	306	4	containing	contain	VBG
cord-312486-rumqopg0	306	5	anti	anti	JJ
cord-312486-rumqopg0	306	6	-	-	NNP
cord-312486-rumqopg0	306	7	S	s	NN
cord-312486-rumqopg0	306	8	-	-	HYPH
cord-312486-rumqopg0	306	9	IgG	igg	NN
cord-312486-rumqopg0	306	10	from	from	IN
cord-312486-rumqopg0	306	11	patients	patient	NNS
cord-312486-rumqopg0	306	12	with	with	IN
cord-312486-rumqopg0	306	13	SARS	SARS	NNP
cord-312486-rumqopg0	306	14	-	-	HYPH
cord-312486-rumqopg0	306	15	CoV-1	CoV-1	NNP
cord-312486-rumqopg0	306	16	enhances	enhance	VBZ
cord-312486-rumqopg0	306	17	the	the	DT
cord-312486-rumqopg0	306	18	infection	infection	NN
cord-312486-rumqopg0	306	19	of	of	IN
cord-312486-rumqopg0	306	20	SARS	SARS	NNP
cord-312486-rumqopg0	306	21	-	-	HYPH
cord-312486-rumqopg0	306	22	CoV-1	CoV-1	NNP
cord-312486-rumqopg0	306	23	in	in	IN
cord-312486-rumqopg0	306	24	human	human	JJ
cord-312486-rumqopg0	306	25	monocyte	monocyte	NN
cord-312486-rumqopg0	306	26	-	-	HYPH
cord-312486-rumqopg0	306	27	derived	derive	VBN
cord-312486-rumqopg0	306	28	macrophages	macrophage	NNS
cord-312486-rumqopg0	306	29	in	in	IN
cord-312486-rumqopg0	306	30	vitro	vitro	FW
cord-312486-rumqopg0	306	31	[	[	-LRB-
cord-312486-rumqopg0	306	32	144	144	CD
cord-312486-rumqopg0	306	33	]	]	-RRB-
cord-312486-rumqopg0	306	34	.	.	.
cord-312486-rumqopg0	307	1	A	a	DT
cord-312486-rumqopg0	307	2	monoclonal	monoclonal	JJ
cord-312486-rumqopg0	307	3	Ab	ab	NN
cord-312486-rumqopg0	307	4	isolated	isolate	VBN
cord-312486-rumqopg0	307	5	from	from	IN
cord-312486-rumqopg0	307	6	a	a	DT
cord-312486-rumqopg0	307	7	patient	patient	NN
cord-312486-rumqopg0	307	8	with	with	IN
cord-312486-rumqopg0	307	9	MERS	MERS	NNP
cord-312486-rumqopg0	307	10	,	,	,
cord-312486-rumqopg0	307	11	targeting	target	VBG
cord-312486-rumqopg0	307	12	the	the	DT
cord-312486-rumqopg0	307	13	S	s	NN
cord-312486-rumqopg0	307	14	-	-	HYPH
cord-312486-rumqopg0	307	15	protein	protein	NN
cord-312486-rumqopg0	307	16	of	of	IN
cord-312486-rumqopg0	307	17	MERS	MERS	NNP
cord-312486-rumqopg0	307	18	-	-	HYPH
cord-312486-rumqopg0	307	19	CoV	CoV	NNP
cord-312486-rumqopg0	307	20	showed	show	VBD
cord-312486-rumqopg0	307	21	FcR	fcr	JJ
cord-312486-rumqopg0	307	22	dependent	dependent	JJ
cord-312486-rumqopg0	307	23	ADH	ADH	NNP
cord-312486-rumqopg0	307	24	[	[	-LRB-
cord-312486-rumqopg0	307	25	145	145	CD
cord-312486-rumqopg0	307	26	]	]	-RRB-
cord-312486-rumqopg0	307	27	.	.	.
cord-312486-rumqopg0	308	1	High	high	JJ
cord-312486-rumqopg0	308	2	dose	dose	NN
cord-312486-rumqopg0	309	1	iv	iv	LS
cord-312486-rumqopg0	309	2	immunoglobin	immunoglobin	NNP
cord-312486-rumqopg0	309	3	(	(	-LRB-
cord-312486-rumqopg0	309	4	IVIg	IVIg	NNP
cord-312486-rumqopg0	309	5	)	)	-RRB-
cord-312486-rumqopg0	309	6	treatment	treatment	NN
cord-312486-rumqopg0	309	7	which	which	WDT
cord-312486-rumqopg0	309	8	has	have	VBZ
cord-312486-rumqopg0	309	9	shown	show	VBN
cord-312486-rumqopg0	309	10	some	some	DT
cord-312486-rumqopg0	309	11	efficacy	efficacy	NN
cord-312486-rumqopg0	309	12	in	in	IN
cord-312486-rumqopg0	309	13	CoV	CoV	NNP
cord-312486-rumqopg0	309	14	including	include	VBG
cord-312486-rumqopg0	309	15	COVID-19	covid-19	VB
cord-312486-rumqopg0	309	16	[	[	-LRB-
cord-312486-rumqopg0	309	17	146	146	CD
cord-312486-rumqopg0	309	18	]	]	-RRB-
cord-312486-rumqopg0	309	19	,	,	,
cord-312486-rumqopg0	309	20	may	may	MD
cord-312486-rumqopg0	309	21	diminish	diminish	VB
cord-312486-rumqopg0	309	22	ADH	ADH	NNP
cord-312486-rumqopg0	309	23	by	by	IN
cord-312486-rumqopg0	309	24	blocking	block	VBG
cord-312486-rumqopg0	309	25	FcR	fcr	NN
cord-312486-rumqopg0	309	26	mediated	mediate	VBN
cord-312486-rumqopg0	309	27	activities	activity	NNS
cord-312486-rumqopg0	309	28	of	of	IN
cord-312486-rumqopg0	309	29	monocytes	monocyte	NNS
cord-312486-rumqopg0	309	30	and	and	CC
cord-312486-rumqopg0	309	31	macrophages	macrophage	NNS
cord-312486-rumqopg0	309	32	.	.	.
cord-312486-rumqopg0	310	1	Direct	direct	JJ
cord-312486-rumqopg0	310	2	evidence	evidence	NN
cord-312486-rumqopg0	310	3	for	for	IN
cord-312486-rumqopg0	310	4	ADE	ADE	NNP
cord-312486-rumqopg0	310	5	was	be	VBD
cord-312486-rumqopg0	310	6	not	not	RB
cord-312486-rumqopg0	310	7	documented	document	VBN
cord-312486-rumqopg0	310	8	in	in	IN
cord-312486-rumqopg0	310	9	COVID-19	covid-19	JJ
cord-312486-rumqopg0	310	10	patients	patient	NNS
cord-312486-rumqopg0	310	11	so	so	RB
cord-312486-rumqopg0	310	12	far	far	RB
cord-312486-rumqopg0	310	13	.	.	.
cord-312486-rumqopg0	311	1	However	however	RB
cord-312486-rumqopg0	311	2	,	,	,
cord-312486-rumqopg0	311	3	as	as	IN
cord-312486-rumqopg0	311	4	argued	argue	VBN
cord-312486-rumqopg0	311	5	[	[	-LRB-
cord-312486-rumqopg0	311	6	147	147	CD
cord-312486-rumqopg0	311	7	]	]	-RRB-
cord-312486-rumqopg0	311	8	,	,	,
cord-312486-rumqopg0	311	9	ADE	ADE	NNP
cord-312486-rumqopg0	311	10	should	should	MD
cord-312486-rumqopg0	311	11	be	be	VB
cord-312486-rumqopg0	311	12	given	give	VBN
cord-312486-rumqopg0	311	13	full	full	JJ
cord-312486-rumqopg0	311	14	consideration	consideration	NN
cord-312486-rumqopg0	311	15	in	in	IN
cord-312486-rumqopg0	311	16	the	the	DT
cord-312486-rumqopg0	311	17	safety	safety	NN
cord-312486-rumqopg0	311	18	evaluation	evaluation	NN
cord-312486-rumqopg0	311	19	of	of	IN
cord-312486-rumqopg0	311	20	emerging	emerge	VBG
cord-312486-rumqopg0	311	21	candidate	candidate	NN
cord-312486-rumqopg0	311	22	vaccines	vaccine	NNS
cord-312486-rumqopg0	311	23	for	for	IN
cord-312486-rumqopg0	311	24	SARS	SARS	NNP
cord-312486-rumqopg0	311	25	-	-	HYPH
cord-312486-rumqopg0	311	26	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	311	27	.	.	.
cord-312486-rumqopg0	312	1	Finally	finally	RB
cord-312486-rumqopg0	312	2	,	,	,
cord-312486-rumqopg0	312	3	it	-PRON-	PRP
cord-312486-rumqopg0	312	4	should	should	MD
cord-312486-rumqopg0	312	5	be	be	VB
cord-312486-rumqopg0	312	6	emphasized	emphasize	VBN
cord-312486-rumqopg0	312	7	that	that	IN
cord-312486-rumqopg0	312	8	at	at	IN
cord-312486-rumqopg0	312	9	present	present	NN
cord-312486-rumqopg0	312	10	,	,	,
cord-312486-rumqopg0	312	11	neither	neither	CC
cord-312486-rumqopg0	312	12	anti	anti	JJ
cord-312486-rumqopg0	312	13	-	-	JJ
cord-312486-rumqopg0	312	14	spike	spike	JJ
cord-312486-rumqopg0	312	15	neutralizing	neutralize	VBG
cord-312486-rumqopg0	312	16	Abs	abs	NN
cord-312486-rumqopg0	312	17	nor	nor	CC
cord-312486-rumqopg0	312	18	anti	anti	JJ
cord-312486-rumqopg0	312	19	-	-	JJ
cord-312486-rumqopg0	312	20	spike	spike	JJ
cord-312486-rumqopg0	312	21	T	t	NN
cord-312486-rumqopg0	312	22	-	-	HYPH
cord-312486-rumqopg0	312	23	cell	cell	NN
cord-312486-rumqopg0	312	24	responses	response	NNS
cord-312486-rumqopg0	312	25	have	have	VBP
cord-312486-rumqopg0	312	26	been	be	VBN
cord-312486-rumqopg0	312	27	established	establish	VBN
cord-312486-rumqopg0	312	28	as	as	IN
cord-312486-rumqopg0	312	29	corollaries	corollary	NNS
cord-312486-rumqopg0	312	30	of	of	IN
cord-312486-rumqopg0	312	31	protection	protection	NN
cord-312486-rumqopg0	312	32	.	.	.
cord-312486-rumqopg0	313	1	Patients	patient	NNS
cord-312486-rumqopg0	313	2	afflicted	afflict	VBN
cord-312486-rumqopg0	313	3	with	with	IN
cord-312486-rumqopg0	313	4	a	a	DT
cord-312486-rumqopg0	313	5	chronic	chronic	JJ
cord-312486-rumqopg0	313	6	autoimmune	autoimmune	JJ
cord-312486-rumqopg0	313	7	disease	disease	NN
cord-312486-rumqopg0	313	8	have	have	VBP
cord-312486-rumqopg0	313	9	an	an	DT
cord-312486-rumqopg0	313	10	increased	increase	VBN
cord-312486-rumqopg0	313	11	risk	risk	NN
cord-312486-rumqopg0	313	12	of	of	IN
cord-312486-rumqopg0	313	13	infections	infection	NNS
cord-312486-rumqopg0	313	14	including	include	VBG
cord-312486-rumqopg0	313	15	viral	viral	JJ
cord-312486-rumqopg0	313	16	infections	infection	NNS
cord-312486-rumqopg0	313	17	[	[	-LRB-
cord-312486-rumqopg0	313	18	148	148	CD
cord-312486-rumqopg0	313	19	,	,	,
cord-312486-rumqopg0	313	20	149	149	CD
cord-312486-rumqopg0	313	21	]	]	-RRB-
cord-312486-rumqopg0	313	22	.	.	.
cord-312486-rumqopg0	314	1	Likewise	likewise	RB
cord-312486-rumqopg0	314	2	,	,	,
cord-312486-rumqopg0	314	3	acute	acute	JJ
cord-312486-rumqopg0	314	4	viral	viral	JJ
cord-312486-rumqopg0	314	5	infections	infection	NNS
cord-312486-rumqopg0	314	6	may	may	MD
cord-312486-rumqopg0	314	7	also	also	RB
cord-312486-rumqopg0	314	8	exacerbate	exacerbate	VB
cord-312486-rumqopg0	314	9	pre	pre	JJ
cord-312486-rumqopg0	314	10	-	-	JJ
cord-312486-rumqopg0	314	11	existing	existing	JJ
cord-312486-rumqopg0	314	12	autoimmune	autoimmune	JJ
cord-312486-rumqopg0	314	13	disease	disease	NN
cord-312486-rumqopg0	314	14	,	,	,
cord-312486-rumqopg0	314	15	and	and	CC
cord-312486-rumqopg0	314	16	immunosuppressive	immunosuppressive	JJ
cord-312486-rumqopg0	314	17	therapies	therapy	NNS
cord-312486-rumqopg0	314	18	may	may	MD
cord-312486-rumqopg0	314	19	render	render	VB
cord-312486-rumqopg0	314	20	patients	patient	NNS
cord-312486-rumqopg0	314	21	with	with	IN
cord-312486-rumqopg0	314	22	autoimmune	autoimmune	JJ
cord-312486-rumqopg0	314	23	disease	disease	NN
cord-312486-rumqopg0	314	24	more	more	RBR
cord-312486-rumqopg0	314	25	vulnerable	vulnerable	JJ
cord-312486-rumqopg0	314	26	to	to	IN
cord-312486-rumqopg0	314	27	viral	viral	JJ
cord-312486-rumqopg0	314	28	infections	infection	NNS
cord-312486-rumqopg0	314	29	.	.	.
cord-312486-rumqopg0	315	1	Despite	despite	IN
cord-312486-rumqopg0	315	2	these	these	DT
cord-312486-rumqopg0	315	3	compounded	compound	VBN
cord-312486-rumqopg0	315	4	considerations	consideration	NNS
cord-312486-rumqopg0	315	5	,	,	,
cord-312486-rumqopg0	315	6	patients	patient	NNS
cord-312486-rumqopg0	315	7	with	with	IN
cord-312486-rumqopg0	315	8	systemic	systemic	JJ
cord-312486-rumqopg0	315	9	or	or	CC
cord-312486-rumqopg0	315	10	organ	organ	NN
cord-312486-rumqopg0	315	11	specific	specific	JJ
cord-312486-rumqopg0	315	12	autoimmune	autoimmune	JJ
cord-312486-rumqopg0	315	13	disease	disease	NN
cord-312486-rumqopg0	315	14	are	be	VBP
cord-312486-rumqopg0	315	15	not	not	RB
cord-312486-rumqopg0	315	16	at	at	IN
cord-312486-rumqopg0	315	17	increased	increase	VBN
cord-312486-rumqopg0	315	18	risk	risk	NN
cord-312486-rumqopg0	315	19	for	for	IN
cord-312486-rumqopg0	315	20	infection	infection	NN
cord-312486-rumqopg0	315	21	with	with	IN
cord-312486-rumqopg0	315	22	SARS	SARS	NNP
cord-312486-rumqopg0	315	23	-	-	HYPH
cord-312486-rumqopg0	315	24	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	315	25	.	.	.
cord-312486-rumqopg0	316	1	In	in	IN
cord-312486-rumqopg0	316	2	fact	fact	NN
cord-312486-rumqopg0	316	3	,	,	,
cord-312486-rumqopg0	316	4	of	of	IN
cord-312486-rumqopg0	316	5	the	the	DT
cord-312486-rumqopg0	316	6	hundreds	hundred	NNS
cord-312486-rumqopg0	316	7	of	of	IN
cord-312486-rumqopg0	316	8	reports	report	NNS
cord-312486-rumqopg0	316	9	published	publish	VBN
cord-312486-rumqopg0	316	10	,	,	,
cord-312486-rumqopg0	316	11	none	none	NN
cord-312486-rumqopg0	316	12	mention	mention	VBP
cord-312486-rumqopg0	316	13	autoimmune	autoimmune	JJ
cord-312486-rumqopg0	316	14	conditions	condition	NNS
cord-312486-rumqopg0	316	15	as	as	IN
cord-312486-rumqopg0	316	16	either	either	DT
cord-312486-rumqopg0	316	17	independent	independent	JJ
cord-312486-rumqopg0	316	18	risk	risk	NN
cord-312486-rumqopg0	316	19	factors	factor	NNS
cord-312486-rumqopg0	316	20	for	for	IN
cord-312486-rumqopg0	316	21	disease	disease	NN
cord-312486-rumqopg0	316	22	or	or	CC
cord-312486-rumqopg0	316	23	as	as	IN
cord-312486-rumqopg0	316	24	indicative	indicative	JJ
cord-312486-rumqopg0	316	25	of	of	IN
cord-312486-rumqopg0	316	26	a	a	DT
cord-312486-rumqopg0	316	27	more	more	RBR
cord-312486-rumqopg0	316	28	severe	severe	JJ
cord-312486-rumqopg0	316	29	outcome	outcome	NN
cord-312486-rumqopg0	316	30	if	if	IN
cord-312486-rumqopg0	316	31	infected	infect	VBN
cord-312486-rumqopg0	316	32	.	.	.
cord-312486-rumqopg0	317	1	The	the	DT
cord-312486-rumqopg0	317	2	data	datum	NNS
cord-312486-rumqopg0	317	3	actually	actually	RB
cord-312486-rumqopg0	317	4	suggests	suggest	VBZ
cord-312486-rumqopg0	317	5	that	that	IN
cord-312486-rumqopg0	317	6	the	the	DT
cord-312486-rumqopg0	317	7	rate	rate	NN
cord-312486-rumqopg0	317	8	of	of	IN
cord-312486-rumqopg0	317	9	infection	infection	NN
cord-312486-rumqopg0	317	10	with	with	IN
cord-312486-rumqopg0	317	11	the	the	DT
cord-312486-rumqopg0	317	12	virus	virus	NN
cord-312486-rumqopg0	317	13	and	and	CC
cord-312486-rumqopg0	317	14	their	-PRON-	PRP$
cord-312486-rumqopg0	317	15	clinical	clinical	JJ
cord-312486-rumqopg0	317	16	course	course	NN
cord-312486-rumqopg0	317	17	is	be	VBZ
cord-312486-rumqopg0	317	18	not	not	RB
cord-312486-rumqopg0	317	19	any	any	RB
cord-312486-rumqopg0	317	20	different	different	JJ
cord-312486-rumqopg0	317	21	from	from	IN
cord-312486-rumqopg0	317	22	that	that	DT
cord-312486-rumqopg0	317	23	of	of	IN
cord-312486-rumqopg0	317	24	the	the	DT
cord-312486-rumqopg0	317	25	general	general	JJ
cord-312486-rumqopg0	317	26	population	population	NN
cord-312486-rumqopg0	317	27	[	[	-LRB-
cord-312486-rumqopg0	317	28	150	150	CD
cord-312486-rumqopg0	317	29	]	]	-RRB-
cord-312486-rumqopg0	317	30	[	[	-LRB-
cord-312486-rumqopg0	317	31	151	151	CD
cord-312486-rumqopg0	317	32	]	]	-RRB-
cord-312486-rumqopg0	317	33	[	[	-LRB-
cord-312486-rumqopg0	317	34	152	152	CD
cord-312486-rumqopg0	317	35	]	]	-RRB-
cord-312486-rumqopg0	317	36	.	.	.
cord-312486-rumqopg0	318	1	Those	those	DT
cord-312486-rumqopg0	318	2	autoimmune	autoimmune	JJ
cord-312486-rumqopg0	318	3	afflicted	afflict	VBN
cord-312486-rumqopg0	318	4	patients	patient	NNS
cord-312486-rumqopg0	318	5	that	that	WDT
cord-312486-rumqopg0	318	6	have	have	VBP
cord-312486-rumqopg0	318	7	develop	develop	VBN
cord-312486-rumqopg0	318	8	severe	severe	JJ
cord-312486-rumqopg0	318	9	COVID-19	covid-19	NN
cord-312486-rumqopg0	318	10	,	,	,
cord-312486-rumqopg0	318	11	are	be	VBP
cord-312486-rumqopg0	318	12	likely	likely	JJ
cord-312486-rumqopg0	318	13	to	to	TO
cord-312486-rumqopg0	318	14	have	have	VB
cord-312486-rumqopg0	318	15	other	other	JJ
cord-312486-rumqopg0	318	16	comorbidities	comorbiditie	NNS
cord-312486-rumqopg0	318	17	that	that	WDT
cord-312486-rumqopg0	318	18	are	be	VBP
cord-312486-rumqopg0	318	19	independent	independent	JJ
cord-312486-rumqopg0	318	20	risk	risk	NN
cord-312486-rumqopg0	318	21	factors	factor	NNS
cord-312486-rumqopg0	318	22	for	for	IN
cord-312486-rumqopg0	318	23	severe	severe	JJ
cord-312486-rumqopg0	318	24	disease	disease	NN
cord-312486-rumqopg0	318	25	.	.	.
cord-312486-rumqopg0	319	1	While	while	IN
cord-312486-rumqopg0	319	2	virus	virus	NN
cord-312486-rumqopg0	319	3	infections	infection	NNS
cord-312486-rumqopg0	319	4	can	can	MD
cord-312486-rumqopg0	319	5	cause	cause	VB
cord-312486-rumqopg0	319	6	flares	flare	NNS
cord-312486-rumqopg0	319	7	in	in	IN
cord-312486-rumqopg0	319	8	otherwise	otherwise	RB
cord-312486-rumqopg0	319	9	stable	stable	JJ
cord-312486-rumqopg0	319	10	autoimmune	autoimmune	JJ
cord-312486-rumqopg0	319	11	disease	disease	NN
cord-312486-rumqopg0	319	12	,	,	,
cord-312486-rumqopg0	319	13	the	the	DT
cord-312486-rumqopg0	319	14	data	data	NN
cord-312486-rumqopg0	319	15	suggests	suggest	VBZ
cord-312486-rumqopg0	319	16	that	that	IN
cord-312486-rumqopg0	319	17	SARS	SARS	NNP
cord-312486-rumqopg0	319	18	-	-	HYPH
cord-312486-rumqopg0	319	19	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	319	20	infection	infection	NN
cord-312486-rumqopg0	319	21	is	be	VBZ
cord-312486-rumqopg0	319	22	not	not	RB
cord-312486-rumqopg0	319	23	associated	associate	VBN
cord-312486-rumqopg0	319	24	with	with	IN
cord-312486-rumqopg0	319	25	increased	increase	VBN
cord-312486-rumqopg0	319	26	incidents	incident	NNS
cord-312486-rumqopg0	319	27	of	of	IN
cord-312486-rumqopg0	319	28	autoimmune	autoimmune	JJ
cord-312486-rumqopg0	319	29	flares	flare	NNS
cord-312486-rumqopg0	319	30	.	.	.
cord-312486-rumqopg0	320	1	I	-PRON-	PRP
cord-312486-rumqopg0	320	2	have	have	VBP
cord-312486-rumqopg0	320	3	previously	previously	RB
cord-312486-rumqopg0	320	4	(	(	-LRB-
cord-312486-rumqopg0	320	5	section	section	NN
cord-312486-rumqopg0	320	6	5	5	CD
cord-312486-rumqopg0	320	7	)	)	-RRB-
cord-312486-rumqopg0	320	8	discussed	discuss	VBD
cord-312486-rumqopg0	320	9	and	and	CC
cord-312486-rumqopg0	320	10	presented	present	VBD
cord-312486-rumqopg0	320	11	evidence	evidence	NN
cord-312486-rumqopg0	320	12	that	that	IN
cord-312486-rumqopg0	320	13	patients	patient	NNS
cord-312486-rumqopg0	320	14	under	under	IN
cord-312486-rumqopg0	320	15	immunosuppressive	immunosuppressive	JJ
cord-312486-rumqopg0	320	16	therapies	therapy	NNS
cord-312486-rumqopg0	320	17	,	,	,
cord-312486-rumqopg0	320	18	including	include	VBG
cord-312486-rumqopg0	320	19	those	those	DT
cord-312486-rumqopg0	320	20	afflicted	afflict	VBN
cord-312486-rumqopg0	320	21	with	with	IN
cord-312486-rumqopg0	320	22	autoimmune	autoimmune	JJ
cord-312486-rumqopg0	320	23	conditions	condition	NNS
cord-312486-rumqopg0	320	24	are	be	VBP
cord-312486-rumqopg0	320	25	not	not	RB
cord-312486-rumqopg0	320	26	at	at	IN
cord-312486-rumqopg0	320	27	increased	increase	VBN
cord-312486-rumqopg0	320	28	risk	risk	NN
cord-312486-rumqopg0	320	29	for	for	IN
cord-312486-rumqopg0	320	30	infection	infection	NN
cord-312486-rumqopg0	320	31	or	or	CC
cord-312486-rumqopg0	320	32	for	for	IN
cord-312486-rumqopg0	320	33	more	more	RBR
cord-312486-rumqopg0	320	34	severe	severe	JJ
cord-312486-rumqopg0	320	35	outcome	outcome	NN
cord-312486-rumqopg0	320	36	[	[	-LRB-
cord-312486-rumqopg0	320	37	121	121	CD
cord-312486-rumqopg0	320	38	,	,	,
cord-312486-rumqopg0	320	39	122	122	CD
cord-312486-rumqopg0	320	40	]	]	-RRB-
cord-312486-rumqopg0	320	41	.	.	.
cord-312486-rumqopg0	321	1	Regarding	regard	VBG
cord-312486-rumqopg0	321	2	SLE	SLE	NNP
cord-312486-rumqopg0	321	3	,	,	,
cord-312486-rumqopg0	321	4	the	the	DT
cord-312486-rumqopg0	321	5	prototypic	prototypic	JJ
cord-312486-rumqopg0	321	6	systemic	systemic	JJ
cord-312486-rumqopg0	321	7	autoimmune	autoimmune	JJ
cord-312486-rumqopg0	321	8	disease	disease	NN
cord-312486-rumqopg0	321	9	,	,	,
cord-312486-rumqopg0	321	10	a	a	DT
cord-312486-rumqopg0	321	11	group	group	NN
cord-312486-rumqopg0	321	12	of	of	IN
cord-312486-rumqopg0	321	13	investigators	investigator	NNS
cord-312486-rumqopg0	321	14	suggested	suggest	VBD
cord-312486-rumqopg0	321	15	that	that	IN
cord-312486-rumqopg0	321	16	inherent	inherent	JJ
cord-312486-rumqopg0	321	17	epigenetic	epigenetic	JJ
cord-312486-rumqopg0	321	18	dysregulation	dysregulation	NN
cord-312486-rumqopg0	321	19	causing	cause	VBG
cord-312486-rumqopg0	321	20	hypomethylation	hypomethylation	NN
cord-312486-rumqopg0	321	21	and	and	CC
cord-312486-rumqopg0	321	22	overexpression	overexpression	NN
cord-312486-rumqopg0	321	23	of	of	IN
cord-312486-rumqopg0	321	24	ACE2	ACE2	NNP
cord-312486-rumqopg0	321	25	,	,	,
cord-312486-rumqopg0	321	26	the	the	DT
cord-312486-rumqopg0	321	27	functional	functional	JJ
cord-312486-rumqopg0	321	28	receptor	receptor	NN
cord-312486-rumqopg0	321	29	for	for	IN
cord-312486-rumqopg0	321	30	SARS	SARS	NNP
cord-312486-rumqopg0	321	31	-	-	HYPH
cord-312486-rumqopg0	321	32	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	321	33	,	,	,
cord-312486-rumqopg0	321	34	might	may	MD
cord-312486-rumqopg0	321	35	facilitate	facilitate	VB
cord-312486-rumqopg0	321	36	viral	viral	JJ
cord-312486-rumqopg0	321	37	J	J	NNP
cord-312486-rumqopg0	321	38	o	o	NN
cord-312486-rumqopg0	321	39	u	u	NN
cord-312486-rumqopg0	321	40	r	r	NN
cord-312486-rumqopg0	321	41	n	n	NN
cord-312486-rumqopg0	321	42	a	a	DT
cord-312486-rumqopg0	321	43	l	l	NN
cord-312486-rumqopg0	321	44	P	p	NN
cord-312486-rumqopg0	321	45	r	r	NN
cord-312486-rumqopg0	321	46	e	e	NN
cord-312486-rumqopg0	322	1	-p	-p	:
cord-312486-rumqopg0	323	1	r	r	NN
cord-312486-rumqopg0	323	2	o	o	NN
cord-312486-rumqopg0	323	3	o	o	NN
cord-312486-rumqopg0	323	4	f	f	NN
cord-312486-rumqopg0	323	5	entry	entry	NN
cord-312486-rumqopg0	323	6	,	,	,
cord-312486-rumqopg0	323	7	viremia	viremia	NN
cord-312486-rumqopg0	323	8	,	,	,
cord-312486-rumqopg0	323	9	and	and	CC
cord-312486-rumqopg0	323	10	increased	increase	VBN
cord-312486-rumqopg0	323	11	likelihood	likelihood	NN
cord-312486-rumqopg0	323	12	of	of	IN
cord-312486-rumqopg0	323	13	cytokine	cytokine	NN
cord-312486-rumqopg0	323	14	storm	storm	NN
cord-312486-rumqopg0	323	15	in	in	IN
cord-312486-rumqopg0	323	16	such	such	JJ
cord-312486-rumqopg0	323	17	patients	patient	NNS
cord-312486-rumqopg0	323	18	[	[	-LRB-
cord-312486-rumqopg0	323	19	153	153	CD
cord-312486-rumqopg0	323	20	]	]	-RRB-
cord-312486-rumqopg0	323	21	.	.	.
cord-312486-rumqopg0	324	1	The	the	DT
cord-312486-rumqopg0	324	2	aforementioned	aforementioned	JJ
cord-312486-rumqopg0	324	3	role	role	NN
cord-312486-rumqopg0	324	4	of	of	IN
cord-312486-rumqopg0	324	5	ACE2	ACE2	NNP
cord-312486-rumqopg0	324	6	expression	expression	NN
cord-312486-rumqopg0	324	7	,	,	,
cord-312486-rumqopg0	324	8	as	as	IN
cord-312486-rumqopg0	324	9	discussed	discuss	VBN
cord-312486-rumqopg0	324	10	above	above	RB
cord-312486-rumqopg0	324	11	,	,	,
cord-312486-rumqopg0	324	12	suggests	suggest	VBZ
cord-312486-rumqopg0	324	13	that	that	IN
cord-312486-rumqopg0	324	14	higher	high	JJR
cord-312486-rumqopg0	324	15	expression	expression	NN
cord-312486-rumqopg0	324	16	of	of	IN
cord-312486-rumqopg0	324	17	ACE2	ACE2	NNP
cord-312486-rumqopg0	324	18	might	may	MD
cord-312486-rumqopg0	324	19	actually	actually	RB
cord-312486-rumqopg0	324	20	benefit	benefit	VB
cord-312486-rumqopg0	324	21	the	the	DT
cord-312486-rumqopg0	324	22	host	host	NN
cord-312486-rumqopg0	324	23	more	more	JJR
cord-312486-rumqopg0	324	24	than	than	IN
cord-312486-rumqopg0	324	25	it	-PRON-	PRP
cord-312486-rumqopg0	324	26	benefits	benefit	VBZ
cord-312486-rumqopg0	324	27	the	the	DT
cord-312486-rumqopg0	324	28	virus	virus	NN
cord-312486-rumqopg0	324	29	.	.	.
cord-312486-rumqopg0	325	1	In	in	IN
cord-312486-rumqopg0	325	2	any	any	DT
cord-312486-rumqopg0	325	3	case	case	NN
cord-312486-rumqopg0	325	4	,	,	,
cord-312486-rumqopg0	325	5	the	the	DT
cord-312486-rumqopg0	325	6	clinical	clinical	JJ
cord-312486-rumqopg0	325	7	experience	experience	NN
cord-312486-rumqopg0	325	8	and	and	CC
cord-312486-rumqopg0	325	9	published	publish	VBN
cord-312486-rumqopg0	325	10	data	datum	NNS
cord-312486-rumqopg0	325	11	do	do	VBP
cord-312486-rumqopg0	325	12	not	not	RB
cord-312486-rumqopg0	325	13	support	support	VB
cord-312486-rumqopg0	325	14	these	these	DT
cord-312486-rumqopg0	325	15	predictions	prediction	NNS
cord-312486-rumqopg0	325	16	.	.	.
cord-312486-rumqopg0	326	1	Moreover	moreover	RB
cord-312486-rumqopg0	326	2	,	,	,
cord-312486-rumqopg0	326	3	the	the	DT
cord-312486-rumqopg0	326	4	accumulating	accumulate	VBG
cord-312486-rumqopg0	326	5	scientific	scientific	JJ
cord-312486-rumqopg0	326	6	information	information	NN
cord-312486-rumqopg0	326	7	does	do	VBZ
cord-312486-rumqopg0	326	8	not	not	RB
cord-312486-rumqopg0	326	9	support	support	VB
cord-312486-rumqopg0	326	10	the	the	DT
cord-312486-rumqopg0	326	11	notion	notion	NN
cord-312486-rumqopg0	326	12	that	that	IN
cord-312486-rumqopg0	326	13	severe	severe	JJ
cord-312486-rumqopg0	326	14	COVID-19	covid-19	NN
cord-312486-rumqopg0	326	15	is	be	VBZ
cord-312486-rumqopg0	326	16	a	a	DT
cord-312486-rumqopg0	326	17	direct	direct	JJ
cord-312486-rumqopg0	326	18	cytopathic	cytopathic	JJ
cord-312486-rumqopg0	326	19	viral	viral	JJ
cord-312486-rumqopg0	326	20	disease	disease	NN
cord-312486-rumqopg0	326	21	,	,	,
cord-312486-rumqopg0	326	22	but	but	CC
cord-312486-rumqopg0	326	23	rather	rather	RB
cord-312486-rumqopg0	326	24	a	a	DT
cord-312486-rumqopg0	326	25	disease	disease	NN
cord-312486-rumqopg0	326	26	in	in	IN
cord-312486-rumqopg0	326	27	which	which	WDT
cord-312486-rumqopg0	326	28	multi	multi	JJ
cord-312486-rumqopg0	326	29	-	-	JJ
cord-312486-rumqopg0	326	30	organ	organ	JJ
cord-312486-rumqopg0	326	31	insult	insult	NN
cord-312486-rumqopg0	326	32	occurs	occur	VBZ
cord-312486-rumqopg0	326	33	by	by	IN
cord-312486-rumqopg0	326	34	the	the	DT
cord-312486-rumqopg0	326	35	host	host	NN
cord-312486-rumqopg0	326	36	's	's	POS
cord-312486-rumqopg0	326	37	own	own	JJ
cord-312486-rumqopg0	326	38	immune	immune	JJ
cord-312486-rumqopg0	326	39	system	system	NN
cord-312486-rumqopg0	326	40	[	[	-LRB-
cord-312486-rumqopg0	326	41	154	154	CD
cord-312486-rumqopg0	326	42	]	]	-RRB-
cord-312486-rumqopg0	326	43	.	.	.
cord-312486-rumqopg0	327	1	Conditions	condition	NNS
cord-312486-rumqopg0	327	2	in	in	IN
cord-312486-rumqopg0	327	3	which	which	WDT
cord-312486-rumqopg0	327	4	the	the	DT
cord-312486-rumqopg0	327	5	immune	immune	JJ
cord-312486-rumqopg0	327	6	system	system	NN
cord-312486-rumqopg0	327	7	attacks	attack	VBZ
cord-312486-rumqopg0	327	8	its	-PRON-	PRP$
cord-312486-rumqopg0	327	9	own	own	JJ
cord-312486-rumqopg0	327	10	tissues	tissue	NNS
cord-312486-rumqopg0	327	11	are	be	VBP
cord-312486-rumqopg0	327	12	usually	usually	RB
cord-312486-rumqopg0	327	13	associated	associate	VBN
cord-312486-rumqopg0	327	14	with	with	IN
cord-312486-rumqopg0	327	15	development	development	NN
cord-312486-rumqopg0	327	16	of	of	IN
cord-312486-rumqopg0	327	17	autoAbs	autoAbs	NNP
cord-312486-rumqopg0	327	18	.	.	.
cord-312486-rumqopg0	328	1	Indeed	indeed	RB
cord-312486-rumqopg0	328	2	,	,	,
cord-312486-rumqopg0	328	3	Gagiannis	Gagiannis	NNP
cord-312486-rumqopg0	328	4	et	et	NNP
cord-312486-rumqopg0	328	5	al	al	NNP
cord-312486-rumqopg0	328	6	.	.	NNP
cord-312486-rumqopg0	328	7	,	,	,
cord-312486-rumqopg0	328	8	studied	study	VBD
cord-312486-rumqopg0	328	9	prospectively	prospectively	RB
cord-312486-rumqopg0	328	10	a	a	DT
cord-312486-rumqopg0	328	11	group	group	NN
cord-312486-rumqopg0	328	12	of	of	IN
cord-312486-rumqopg0	328	13	22	22	CD
cord-312486-rumqopg0	328	14	patients	patient	NNS
cord-312486-rumqopg0	328	15	for	for	IN
cord-312486-rumqopg0	328	16	the	the	DT
cord-312486-rumqopg0	328	17	possible	possible	JJ
cord-312486-rumqopg0	328	18	role	role	NN
cord-312486-rumqopg0	328	19	of	of	IN
cord-312486-rumqopg0	328	20	autoimmunity	autoimmunity	NN
cord-312486-rumqopg0	328	21	in	in	IN
cord-312486-rumqopg0	328	22	COVID-19	covid-19	JJ
cord-312486-rumqopg0	328	23	patients	patient	NNS
cord-312486-rumqopg0	328	24	[	[	-LRB-
cord-312486-rumqopg0	328	25	155	155	CD
cord-312486-rumqopg0	328	26	]	]	-RRB-
cord-312486-rumqopg0	328	27	.	.	.
cord-312486-rumqopg0	329	1	AutoAb	AutoAb	NNP
cord-312486-rumqopg0	329	2	titers	titer	NNS
cord-312486-rumqopg0	330	1	≥1:100	≥1:100	NNP
cord-312486-rumqopg0	330	2	were	be	VBD
cord-312486-rumqopg0	330	3	detected	detect	VBN
cord-312486-rumqopg0	330	4	in	in	IN
cord-312486-rumqopg0	330	5	10/11	10/11	CD
cord-312486-rumqopg0	331	1	COVID-19	covid-19	JJ
cord-312486-rumqopg0	331	2	patients	patient	NNS
cord-312486-rumqopg0	331	3	who	who	WP
cord-312486-rumqopg0	331	4	required	require	VBD
cord-312486-rumqopg0	331	5	intensive	intensive	JJ
cord-312486-rumqopg0	331	6	care	care	NN
cord-312486-rumqopg0	331	7	treatment	treatment	NN
cord-312486-rumqopg0	331	8	,	,	,
cord-312486-rumqopg0	331	9	and	and	CC
cord-312486-rumqopg0	331	10	in	in	IN
cord-312486-rumqopg0	331	11	4/11	4/11	CD
cord-312486-rumqopg0	331	12	patients	patient	NNS
cord-312486-rumqopg0	331	13	with	with	IN
cord-312486-rumqopg0	331	14	milder	mild	JJR
cord-312486-rumqopg0	331	15	clinical	clinical	JJ
cord-312486-rumqopg0	331	16	course	course	NN
cord-312486-rumqopg0	331	17	.	.	.
cord-312486-rumqopg0	332	1	Based	base	VBN
cord-312486-rumqopg0	332	2	on	on	IN
cord-312486-rumqopg0	332	3	serological	serological	JJ
cord-312486-rumqopg0	332	4	,	,	,
cord-312486-rumqopg0	332	5	radiological	radiological	JJ
cord-312486-rumqopg0	332	6	,	,	,
cord-312486-rumqopg0	332	7	and	and	CC
cord-312486-rumqopg0	332	8	histopathological	histopathological	JJ
cord-312486-rumqopg0	332	9	similarities	similarity	NNS
cord-312486-rumqopg0	332	10	between	between	IN
cord-312486-rumqopg0	332	11	COVID-19-associated	COVID-19-associated	NNP
cord-312486-rumqopg0	332	12	ARDS	ARDS	NNP
cord-312486-rumqopg0	332	13	and	and	CC
cord-312486-rumqopg0	332	14	acute	acute	JJ
cord-312486-rumqopg0	332	15	exacerbation	exacerbation	NN
cord-312486-rumqopg0	332	16	of	of	IN
cord-312486-rumqopg0	332	17	connective	connective	JJ
cord-312486-rumqopg0	332	18	tissue	tissue	NN
cord-312486-rumqopg0	332	19	disease	disease	NN
cord-312486-rumqopg0	332	20	induced	induce	VBN
cord-312486-rumqopg0	332	21	interstitial	interstitial	JJ
cord-312486-rumqopg0	332	22	lung	lung	NN
cord-312486-rumqopg0	332	23	disease	disease	NN
cord-312486-rumqopg0	332	24	,	,	,
cord-312486-rumqopg0	332	25	these	these	DT
cord-312486-rumqopg0	332	26	authors	author	NNS
cord-312486-rumqopg0	332	27	suggest	suggest	VBP
cord-312486-rumqopg0	332	28	that	that	IN
cord-312486-rumqopg0	332	29	SARS	SARS	NNP
cord-312486-rumqopg0	332	30	-	-	HYPH
cord-312486-rumqopg0	332	31	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	332	32	infection	infection	NN
cord-312486-rumqopg0	332	33	might	may	MD
cord-312486-rumqopg0	332	34	trigger	trigger	VB
cord-312486-rumqopg0	332	35	or	or	CC
cord-312486-rumqopg0	332	36	simulate	simulate	VB
cord-312486-rumqopg0	332	37	a	a	DT
cord-312486-rumqopg0	332	38	form	form	NN
cord-312486-rumqopg0	332	39	of	of	IN
cord-312486-rumqopg0	332	40	organ	organ	NN
cord-312486-rumqopg0	332	41	specific	specific	JJ
cord-312486-rumqopg0	332	42	autoimmunity	autoimmunity	NN
cord-312486-rumqopg0	332	43	[	[	-LRB-
cord-312486-rumqopg0	332	44	155	155	CD
cord-312486-rumqopg0	332	45	]	]	-RRB-
cord-312486-rumqopg0	332	46	.	.	.
cord-312486-rumqopg0	333	1	Similarly	similarly	RB
cord-312486-rumqopg0	333	2	,	,	,
cord-312486-rumqopg0	333	3	Zhou	Zhou	NNP
cord-312486-rumqopg0	333	4	et	et	NNP
cord-312486-rumqopg0	333	5	al	al	NNP
cord-312486-rumqopg0	333	6	.	.	.
cord-312486-rumqopg0	334	1	,	,	,
cord-312486-rumqopg0	334	2	report	report	VB
cord-312486-rumqopg0	334	3	on	on	IN
cord-312486-rumqopg0	334	4	autoAbs	autoabs	CD
cord-312486-rumqopg0	334	5	in	in	IN
cord-312486-rumqopg0	334	6	21	21	CD
cord-312486-rumqopg0	334	7	severe	severe	JJ
cord-312486-rumqopg0	334	8	COVID-19	covid-19	JJ
cord-312486-rumqopg0	334	9	patients	patient	NNS
cord-312486-rumqopg0	334	10	.	.	.
cord-312486-rumqopg0	335	1	The	the	DT
cord-312486-rumqopg0	335	2	prevalence	prevalence	NN
cord-312486-rumqopg0	335	3	of	of	IN
cord-312486-rumqopg0	335	4	anti-52	anti-52	NNP
cord-312486-rumqopg0	335	5	kDa	kDa	NNP
cord-312486-rumqopg0	335	6	SSA	SSA	NNP
cord-312486-rumqopg0	335	7	/	/	SYM
cord-312486-rumqopg0	335	8	Ro	Ro	NNP
cord-312486-rumqopg0	335	9	Ab	Ab	NNP
cord-312486-rumqopg0	335	10	,	,	,
cord-312486-rumqopg0	335	11	anti-60	anti-60	NNP
cord-312486-rumqopg0	335	12	kDa	kDa	NNP
cord-312486-rumqopg0	335	13	SSA	SSA	NNP
cord-312486-rumqopg0	335	14	/	/	SYM
cord-312486-rumqopg0	335	15	Ro	Ro	NNP
cord-312486-rumqopg0	335	16	Ab	Ab	NNP
cord-312486-rumqopg0	335	17	,	,	,
cord-312486-rumqopg0	335	18	and	and	CC
cord-312486-rumqopg0	335	19	antinuclear	antinuclear	JJ
cord-312486-rumqopg0	335	20	Ab	ab	NN
cord-312486-rumqopg0	335	21	(	(	-LRB-
cord-312486-rumqopg0	335	22	ANA	ANA	NNP
cord-312486-rumqopg0	335	23	)	)	-RRB-
cord-312486-rumqopg0	335	24	was	be	VBD
cord-312486-rumqopg0	335	25	20	20	CD
cord-312486-rumqopg0	335	26	%	%	NN
cord-312486-rumqopg0	335	27	,	,	,
cord-312486-rumqopg0	335	28	25	25	CD
cord-312486-rumqopg0	335	29	%	%	NN
cord-312486-rumqopg0	335	30	,	,	,
cord-312486-rumqopg0	335	31	and	and	CC
cord-312486-rumqopg0	335	32	50	50	CD
cord-312486-rumqopg0	335	33	%	%	NN
cord-312486-rumqopg0	335	34	,	,	,
cord-312486-rumqopg0	335	35	respectively	respectively	RB
cord-312486-rumqopg0	335	36	[	[	-LRB-
cord-312486-rumqopg0	335	37	108	108	CD
cord-312486-rumqopg0	335	38	]	]	-RRB-
cord-312486-rumqopg0	335	39	.	.	.
cord-312486-rumqopg0	336	1	ANA	ANA	NNP
cord-312486-rumqopg0	336	2	was	be	VBD
cord-312486-rumqopg0	336	3	reported	report	VBN
cord-312486-rumqopg0	336	4	in	in	IN
cord-312486-rumqopg0	336	5	over	over	IN
cord-312486-rumqopg0	336	6	35	35	CD
cord-312486-rumqopg0	336	7	%	%	NN
cord-312486-rumqopg0	336	8	of	of	IN
cord-312486-rumqopg0	336	9	45	45	CD
cord-312486-rumqopg0	336	10	consecutive	consecutive	JJ
cord-312486-rumqopg0	336	11	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	336	12	patients	patient	NNS
cord-312486-rumqopg0	336	13	[	[	-LRB-
cord-312486-rumqopg0	336	14	110	110	CD
cord-312486-rumqopg0	336	15	]	]	-RRB-
cord-312486-rumqopg0	336	16	.	.	.
cord-312486-rumqopg0	337	1	Several	several	JJ
cord-312486-rumqopg0	337	2	studies	study	NNS
cord-312486-rumqopg0	337	3	document	document	VBP
cord-312486-rumqopg0	337	4	different	different	JJ
cord-312486-rumqopg0	337	5	aPL	aPL	.
cord-312486-rumqopg0	337	6	Abs	Abs	NNP
cord-312486-rumqopg0	337	7	in	in	IN
cord-312486-rumqopg0	337	8	COVID-19	covid-19	JJ
cord-312486-rumqopg0	337	9	patients	patient	NNS
cord-312486-rumqopg0	337	10	mostly	mostly	RB
cord-312486-rumqopg0	337	11	associated	associate	VBN
cord-312486-rumqopg0	337	12	with	with	IN
cord-312486-rumqopg0	337	13	thrombotic	thrombotic	JJ
cord-312486-rumqopg0	337	14	phenomena	phenomenon	NNS
cord-312486-rumqopg0	337	15	[	[	-LRB-
cord-312486-rumqopg0	337	16	108	108	CD
cord-312486-rumqopg0	337	17	-	-	SYM
cord-312486-rumqopg0	337	18	110	110	CD
cord-312486-rumqopg0	337	19	,	,	,
cord-312486-rumqopg0	337	20	156	156	CD
cord-312486-rumqopg0	337	21	,	,	,
cord-312486-rumqopg0	337	22	157	157	CD
cord-312486-rumqopg0	337	23	]	]	-RRB-
cord-312486-rumqopg0	337	24	.	.	.
cord-312486-rumqopg0	338	1	Whether	whether	IN
cord-312486-rumqopg0	338	2	aPL	aPL	NNP
cord-312486-rumqopg0	338	3	in	in	IN
cord-312486-rumqopg0	338	4	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	338	5	is	be	VBZ
cord-312486-rumqopg0	338	6	transient	transient	JJ
cord-312486-rumqopg0	338	7	,	,	,
cord-312486-rumqopg0	338	8	as	as	IN
cord-312486-rumqopg0	338	9	has	have	VBZ
cord-312486-rumqopg0	338	10	been	be	VBN
cord-312486-rumqopg0	338	11	documented	document	VBN
cord-312486-rumqopg0	338	12	in	in	IN
cord-312486-rumqopg0	338	13	many	many	JJ
cord-312486-rumqopg0	338	14	other	other	JJ
cord-312486-rumqopg0	338	15	viral	viral	JJ
cord-312486-rumqopg0	338	16	infections	infection	NNS
cord-312486-rumqopg0	338	17	,	,	,
cord-312486-rumqopg0	338	18	or	or	CC
cord-312486-rumqopg0	338	19	develops	develop	VBZ
cord-312486-rumqopg0	338	20	into	into	IN
cord-312486-rumqopg0	338	21	persistent	persistent	JJ
cord-312486-rumqopg0	338	22	and	and	CC
cord-312486-rumqopg0	338	23	pathogenic	pathogenic	JJ
cord-312486-rumqopg0	338	24	,	,	,
cord-312486-rumqopg0	338	25	is	be	VBZ
cord-312486-rumqopg0	338	26	very	very	RB
cord-312486-rumqopg0	338	27	difficult	difficult	JJ
cord-312486-rumqopg0	338	28	to	to	TO
cord-312486-rumqopg0	338	29	judge	judge	VB
cord-312486-rumqopg0	338	30	from	from	IN
cord-312486-rumqopg0	338	31	the	the	DT
cord-312486-rumqopg0	338	32	results	result	NNS
cord-312486-rumqopg0	338	33	published	publish	VBN
cord-312486-rumqopg0	338	34	so	so	RB
cord-312486-rumqopg0	338	35	far	far	RB
cord-312486-rumqopg0	338	36	.	.	.
cord-312486-rumqopg0	339	1	Pregnancy	pregnancy	NN
cord-312486-rumqopg0	339	2	related	relate	VBD
cord-312486-rumqopg0	339	3	morbidity	morbidity	NN
cord-312486-rumqopg0	339	4	with	with	IN
cord-312486-rumqopg0	339	5	fetal	fetal	JJ
cord-312486-rumqopg0	339	6	losses	loss	NNS
cord-312486-rumqopg0	339	7	have	have	VBP
cord-312486-rumqopg0	339	8	not	not	RB
cord-312486-rumqopg0	339	9	been	be	VBN
cord-312486-rumqopg0	339	10	reported	report	VBN
cord-312486-rumqopg0	339	11	in	in	IN
cord-312486-rumqopg0	339	12	connection	connection	NN
cord-312486-rumqopg0	339	13	with	with	IN
cord-312486-rumqopg0	339	14	SARS	SARS	NNP
cord-312486-rumqopg0	339	15	-	-	HYPH
cord-312486-rumqopg0	339	16	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	339	17	infections	infection	NNS
cord-312486-rumqopg0	339	18	.	.	.
cord-312486-rumqopg0	340	1	However	however	RB
cord-312486-rumqopg0	340	2	,	,	,
cord-312486-rumqopg0	340	3	since	since	IN
cord-312486-rumqopg0	340	4	an	an	DT
cord-312486-rumqopg0	340	5	infection	infection	NN
cord-312486-rumqopg0	340	6	often	often	RB
cord-312486-rumqopg0	340	7	precedes	precede	VBZ
cord-312486-rumqopg0	340	8	the	the	DT
cord-312486-rumqopg0	340	9	clinical	clinical	JJ
cord-312486-rumqopg0	340	10	onset	onset	NN
cord-312486-rumqopg0	340	11	of	of	IN
cord-312486-rumqopg0	340	12	APS	APS	NNP
cord-312486-rumqopg0	340	13	,	,	,
cord-312486-rumqopg0	340	14	it	-PRON-	PRP
cord-312486-rumqopg0	340	15	is	be	VBZ
cord-312486-rumqopg0	340	16	certainly	certainly	RB
cord-312486-rumqopg0	340	17	justified	justified	JJ
cord-312486-rumqopg0	340	18	to	to	TO
cord-312486-rumqopg0	340	19	follow	follow	VB
cord-312486-rumqopg0	340	20	up	up	RP
cord-312486-rumqopg0	340	21	a	a	DT
cord-312486-rumqopg0	340	22	positive	positive	JJ
cord-312486-rumqopg0	340	23	aPL	apl	CD
cord-312486-rumqopg0	340	24	test	test	NN
cord-312486-rumqopg0	340	25	in	in	IN
cord-312486-rumqopg0	340	26	a	a	DT
cord-312486-rumqopg0	340	27	COVID-19	covid-19	JJ
cord-312486-rumqopg0	340	28	patient	patient	NN
cord-312486-rumqopg0	340	29	with	with	IN
cord-312486-rumqopg0	340	30	a	a	DT
cord-312486-rumqopg0	340	31	repeated	repeat	VBN
cord-312486-rumqopg0	340	32	test	test	NN
cord-312486-rumqopg0	340	33	approximately	approximately	RB
cord-312486-rumqopg0	340	34	twelve	twelve	CD
cord-312486-rumqopg0	340	35	weeks	week	NNS
cord-312486-rumqopg0	340	36	later	later	RB
cord-312486-rumqopg0	340	37	to	to	TO
cord-312486-rumqopg0	340	38	further	further	RB
cord-312486-rumqopg0	340	39	evaluate	evaluate	VB
cord-312486-rumqopg0	340	40	the	the	DT
cord-312486-rumqopg0	340	41	possibility	possibility	NN
cord-312486-rumqopg0	340	42	of	of	IN
cord-312486-rumqopg0	340	43	post	post	JJ
cord-312486-rumqopg0	340	44	-	-	JJ
cord-312486-rumqopg0	340	45	infectious	infectious	JJ
cord-312486-rumqopg0	340	46	APS	APS	NNP
cord-312486-rumqopg0	340	47	.	.	.
cord-312486-rumqopg0	341	1	A	a	DT
cord-312486-rumqopg0	341	2	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	341	3	-	-	HYPH
cord-312486-rumqopg0	341	4	like	like	JJ
cord-312486-rumqopg0	341	5	disease	disease	NN
cord-312486-rumqopg0	341	6	seen	see	VBN
cord-312486-rumqopg0	341	7	in	in	IN
cord-312486-rumqopg0	341	8	children	child	NNS
cord-312486-rumqopg0	341	9	is	be	VBZ
cord-312486-rumqopg0	341	10	the	the	DT
cord-312486-rumqopg0	341	11	closest	close	JJS
cord-312486-rumqopg0	341	12	link	link	NN
cord-312486-rumqopg0	341	13	between	between	IN
cord-312486-rumqopg0	341	14	SARS	SARS	NNP
cord-312486-rumqopg0	341	15	-	-	HYPH
cord-312486-rumqopg0	341	16	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	341	17	and	and	CC
cord-312486-rumqopg0	341	18	the	the	DT
cord-312486-rumqopg0	341	19	appearance	appearance	NN
cord-312486-rumqopg0	341	20	of	of	IN
cord-312486-rumqopg0	341	21	an	an	DT
cord-312486-rumqopg0	341	22	autoimmune	autoimmune	NN
cord-312486-rumqopg0	341	23	and/or	and/or	CC
cord-312486-rumqopg0	341	24	autoinflammatory	autoinflammatory	JJ
cord-312486-rumqopg0	341	25	condition	condition	NN
cord-312486-rumqopg0	341	26	.	.	.
cord-312486-rumqopg0	342	1	Investigators	investigator	NNS
cord-312486-rumqopg0	342	2	from	from	IN
cord-312486-rumqopg0	342	3	Italy	Italy	NNP
cord-312486-rumqopg0	342	4	's	's	POS
cord-312486-rumqopg0	342	5	pandemic	pandemic	JJ
cord-312486-rumqopg0	342	6	epicenter	epicenter	NN
cord-312486-rumqopg0	342	7	in	in	IN
cord-312486-rumqopg0	342	8	Bergamo	Bergamo	NNP
cord-312486-rumqopg0	342	9	were	be	VBD
cord-312486-rumqopg0	342	10	the	the	DT
cord-312486-rumqopg0	342	11	first	first	JJ
cord-312486-rumqopg0	342	12	to	to	TO
cord-312486-rumqopg0	342	13	focus	focus	VB
cord-312486-rumqopg0	342	14	attention	attention	NN
cord-312486-rumqopg0	342	15	on	on	IN
cord-312486-rumqopg0	342	16	this	this	DT
cord-312486-rumqopg0	342	17	disorder	disorder	NN
cord-312486-rumqopg0	342	18	[	[	-LRB-
cord-312486-rumqopg0	342	19	158	158	CD
cord-312486-rumqopg0	342	20	]	]	-RRB-
cord-312486-rumqopg0	342	21	.	.	.
cord-312486-rumqopg0	343	1	D'Antiga	D'Antiga	NNP
cord-312486-rumqopg0	343	2	and	and	CC
cord-312486-rumqopg0	343	3	his	-PRON-	PRP$
cord-312486-rumqopg0	343	4	colleagues	colleague	NNS
cord-312486-rumqopg0	343	5	,	,	,
cord-312486-rumqopg0	343	6	quantified	quantify	VBD
cord-312486-rumqopg0	343	7	the	the	DT
cord-312486-rumqopg0	343	8	time	time	NN
cord-312486-rumqopg0	343	9	course	course	NN
cord-312486-rumqopg0	343	10	and	and	CC
cord-312486-rumqopg0	343	11	incidence	incidence	NN
cord-312486-rumqopg0	343	12	of	of	IN
cord-312486-rumqopg0	343	13	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	343	14	-	-	HYPH
cord-312486-rumqopg0	343	15	like	like	JJ
cord-312486-rumqopg0	343	16	disease	disease	NN
cord-312486-rumqopg0	343	17	in	in	IN
cord-312486-rumqopg0	343	18	children	child	NNS
cord-312486-rumqopg0	343	19	before	before	RB
cord-312486-rumqopg0	343	20	and	and	CC
cord-312486-rumqopg0	343	21	after	after	IN
cord-312486-rumqopg0	343	22	the	the	DT
cord-312486-rumqopg0	343	23	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	343	24	pandemic	pandemic	NN
cord-312486-rumqopg0	343	25	,	,	,
cord-312486-rumqopg0	343	26	documenting	document	VBG
cord-312486-rumqopg0	343	27	a	a	DT
cord-312486-rumqopg0	343	28	thirty	thirty	CD
cord-312486-rumqopg0	343	29	-	-	HYPH
cord-312486-rumqopg0	343	30	fold	fold	JJ
cord-312486-rumqopg0	343	31	increase	increase	NN
cord-312486-rumqopg0	343	32	in	in	IN
cord-312486-rumqopg0	343	33	incidence	incidence	NN
cord-312486-rumqopg0	343	34	of	of	IN
cord-312486-rumqopg0	343	35	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	343	36	-	-	HYPH
cord-312486-rumqopg0	343	37	like	like	JJ
cord-312486-rumqopg0	343	38	disease	disease	NN
cord-312486-rumqopg0	343	39	after	after	IN
cord-312486-rumqopg0	343	40	the	the	DT
cord-312486-rumqopg0	343	41	beginning	beginning	NN
cord-312486-rumqopg0	343	42	of	of	IN
cord-312486-rumqopg0	343	43	the	the	DT
cord-312486-rumqopg0	343	44	pandemic	pandemic	NN
cord-312486-rumqopg0	343	45	[	[	-LRB-
cord-312486-rumqopg0	343	46	158	158	CD
cord-312486-rumqopg0	343	47	]	]	-RRB-
cord-312486-rumqopg0	343	48	.	.	.
cord-312486-rumqopg0	344	1	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	344	2	disease	disease	NN
cord-312486-rumqopg0	344	3	is	be	VBZ
cord-312486-rumqopg0	344	4	an	an	DT
cord-312486-rumqopg0	344	5	acute	acute	JJ
cord-312486-rumqopg0	344	6	and	and	CC
cord-312486-rumqopg0	344	7	usually	usually	RB
cord-312486-rumqopg0	344	8	self	self	NN
cord-312486-rumqopg0	344	9	-	-	HYPH
cord-312486-rumqopg0	344	10	limiting	limit	VBG
cord-312486-rumqopg0	344	11	vasculitis	vasculitis	NN
cord-312486-rumqopg0	344	12	of	of	IN
cord-312486-rumqopg0	344	13	medium	medium	JJ
cord-312486-rumqopg0	344	14	and	and	CC
cord-312486-rumqopg0	344	15	small	small	JJ
cord-312486-rumqopg0	344	16	sized	sized	JJ
cord-312486-rumqopg0	344	17	arteries	artery	NNS
cord-312486-rumqopg0	344	18	with	with	IN
cord-312486-rumqopg0	344	19	specific	specific	JJ
cord-312486-rumqopg0	344	20	predilection	predilection	NN
cord-312486-rumqopg0	344	21	for	for	IN
cord-312486-rumqopg0	344	22	the	the	DT
cord-312486-rumqopg0	344	23	coronary	coronary	JJ
cord-312486-rumqopg0	344	24	arteries	artery	NNS
cord-312486-rumqopg0	344	25	that	that	WDT
cord-312486-rumqopg0	344	26	affects	affect	VBZ
cord-312486-rumqopg0	344	27	previously	previously	RB
cord-312486-rumqopg0	344	28	healthy	healthy	JJ
cord-312486-rumqopg0	344	29	young	young	JJ
cord-312486-rumqopg0	344	30	children	child	NNS
cord-312486-rumqopg0	344	31	typically	typically	RB
cord-312486-rumqopg0	344	32	under	under	IN
cord-312486-rumqopg0	344	33	the	the	DT
cord-312486-rumqopg0	344	34	age	age	NN
cord-312486-rumqopg0	344	35	of	of	IN
cord-312486-rumqopg0	344	36	five	five	CD
cord-312486-rumqopg0	344	37	years	year	NNS
cord-312486-rumqopg0	344	38	.	.	.
cord-312486-rumqopg0	345	1	In	in	IN
cord-312486-rumqopg0	345	2	the	the	DT
cord-312486-rumqopg0	345	3	acute	acute	JJ
cord-312486-rumqopg0	345	4	phase	phase	NN
cord-312486-rumqopg0	345	5	of	of	IN
cord-312486-rumqopg0	345	6	the	the	DT
cord-312486-rumqopg0	345	7	disease	disease	NN
cord-312486-rumqopg0	345	8	,	,	,
cord-312486-rumqopg0	345	9	patients	patient	NNS
cord-312486-rumqopg0	345	10	with	with	IN
cord-312486-rumqopg0	345	11	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	345	12	disease	disease	NN
cord-312486-rumqopg0	345	13	might	may	MD
cord-312486-rumqopg0	345	14	have	have	VB
cord-312486-rumqopg0	345	15	hemodynamic	hemodynamic	JJ
cord-312486-rumqopg0	345	16	instability	instability	NN
cord-312486-rumqopg0	345	17	,	,	,
cord-312486-rumqopg0	345	18	a	a	DT
cord-312486-rumqopg0	345	19	condition	condition	NN
cord-312486-rumqopg0	345	20	known	know	VBN
cord-312486-rumqopg0	345	21	as	as	IN
cord-312486-rumqopg0	345	22	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	345	23	disease	disease	NN
cord-312486-rumqopg0	345	24	shock	shock	NN
cord-312486-rumqopg0	345	25	syndrome	syndrome	NN
cord-312486-rumqopg0	345	26	.	.	.
cord-312486-rumqopg0	346	1	Same	same	JJ
cord-312486-rumqopg0	346	2	patients	patient	NNS
cord-312486-rumqopg0	346	3	with	with	IN
cord-312486-rumqopg0	346	4	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	346	5	disease	disease	NN
cord-312486-rumqopg0	346	6	fulfil	fulfil	VBP
cord-312486-rumqopg0	346	7	the	the	DT
cord-312486-rumqopg0	346	8	criteria	criterion	NNS
cord-312486-rumqopg0	346	9	of	of	IN
cord-312486-rumqopg0	346	10	macrophage	macrophage	NN
cord-312486-rumqopg0	346	11	activation	activation	NN
cord-312486-rumqopg0	346	12	syndrome	syndrome	NN
cord-312486-rumqopg0	346	13	(	(	-LRB-
cord-312486-rumqopg0	346	14	MAS	MAS	NNP
cord-312486-rumqopg0	346	15	)	)	-RRB-
cord-312486-rumqopg0	346	16	.	.	.
cord-312486-rumqopg0	347	1	An	an	DT
cord-312486-rumqopg0	347	2	association	association	NN
cord-312486-rumqopg0	347	3	between	between	IN
cord-312486-rumqopg0	347	4	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	347	5	disease	disease	NN
cord-312486-rumqopg0	347	6	and	and	CC
cord-312486-rumqopg0	347	7	various	various	JJ
cord-312486-rumqopg0	347	8	viral	viral	JJ
cord-312486-rumqopg0	347	9	infections	infection	NNS
cord-312486-rumqopg0	347	10	have	have	VBP
cord-312486-rumqopg0	347	11	been	be	VBN
cord-312486-rumqopg0	347	12	suspected	suspect	VBN
cord-312486-rumqopg0	347	13	,	,	,
cord-312486-rumqopg0	347	14	including	include	VBG
cord-312486-rumqopg0	347	15	viruses	virus	NNS
cord-312486-rumqopg0	347	16	of	of	IN
cord-312486-rumqopg0	347	17	the	the	DT
cord-312486-rumqopg0	347	18	coronavirus	coronavirus	NN
cord-312486-rumqopg0	347	19	family	family	NN
cord-312486-rumqopg0	347	20	,	,	,
cord-312486-rumqopg0	347	21	however	however	RB
cord-312486-rumqopg0	347	22	a	a	DT
cord-312486-rumqopg0	347	23	specific	specific	JJ
cord-312486-rumqopg0	347	24	infectious	infectious	JJ
cord-312486-rumqopg0	347	25	trigger	trigger	NN
cord-312486-rumqopg0	347	26	has	have	VBZ
cord-312486-rumqopg0	347	27	yet	yet	RB
cord-312486-rumqopg0	347	28	to	to	TO
cord-312486-rumqopg0	347	29	be	be	VB
cord-312486-rumqopg0	347	30	identified	identify	VBN
cord-312486-rumqopg0	347	31	.	.	.
cord-312486-rumqopg0	348	1	SARS	SARS	NNP
cord-312486-rumqopg0	348	2	-	-	HYPH
cord-312486-rumqopg0	348	3	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	348	4	should	should	MD
cord-312486-rumqopg0	348	5	be	be	VB
cord-312486-rumqopg0	348	6	now	now	RB
cord-312486-rumqopg0	348	7	added	add	VBN
cord-312486-rumqopg0	348	8	to	to	IN
cord-312486-rumqopg0	348	9	the	the	DT
cord-312486-rumqopg0	348	10	list	list	NN
cord-312486-rumqopg0	348	11	of	of	IN
cord-312486-rumqopg0	348	12	implicated	implicated	JJ
cord-312486-rumqopg0	348	13	viruses	virus	NNS
cord-312486-rumqopg0	348	14	.	.	.
cord-312486-rumqopg0	349	1	The	the	DT
cord-312486-rumqopg0	349	2	most	most	RBS
cord-312486-rumqopg0	349	3	accepted	accept	VBN
cord-312486-rumqopg0	349	4	pathogenetic	pathogenetic	JJ
cord-312486-rumqopg0	349	5	hypothesis	hypothesis	NN
cord-312486-rumqopg0	349	6	supports	support	VBZ
cord-312486-rumqopg0	349	7	J	J	NNP
cord-312486-rumqopg0	349	8	o	o	NN
cord-312486-rumqopg0	349	9	u	u	NN
cord-312486-rumqopg0	349	10	r	r	NN
cord-312486-rumqopg0	349	11	n	n	NN
cord-312486-rumqopg0	349	12	a	a	DT
cord-312486-rumqopg0	349	13	l	l	NN
cord-312486-rumqopg0	349	14	P	p	NN
cord-312486-rumqopg0	349	15	r	r	NN
cord-312486-rumqopg0	349	16	e	e	NN
cord-312486-rumqopg0	350	1	-p	-p	:
cord-312486-rumqopg0	351	1	r	r	NNP
cord-312486-rumqopg0	351	2	o	o	NN
cord-312486-rumqopg0	351	3	o	o	NN
cord-312486-rumqopg0	351	4	f	f	NN
cord-312486-rumqopg0	351	5	an	an	DT
cord-312486-rumqopg0	351	6	aberrant	aberrant	JJ
cord-312486-rumqopg0	351	7	response	response	NN
cord-312486-rumqopg0	351	8	of	of	IN
cord-312486-rumqopg0	351	9	the	the	DT
cord-312486-rumqopg0	351	10	immune	immune	JJ
cord-312486-rumqopg0	351	11	system	system	NN
cord-312486-rumqopg0	351	12	to	to	IN
cord-312486-rumqopg0	351	13	one	one	CD
cord-312486-rumqopg0	351	14	or	or	CC
cord-312486-rumqopg0	351	15	more	more	JJR
cord-312486-rumqopg0	351	16	unidentified	unidentified	JJ
cord-312486-rumqopg0	351	17	pathogens	pathogen	NNS
cord-312486-rumqopg0	351	18	in	in	IN
cord-312486-rumqopg0	351	19	genetically	genetically	RB
cord-312486-rumqopg0	351	20	predisposed	predisposed	JJ
cord-312486-rumqopg0	351	21	subjects	subject	NNS
cord-312486-rumqopg0	351	22	.	.	.
cord-312486-rumqopg0	352	1	Following	follow	VBG
cord-312486-rumqopg0	352	2	the	the	DT
cord-312486-rumqopg0	352	3	report	report	NN
cord-312486-rumqopg0	352	4	from	from	IN
cord-312486-rumqopg0	352	5	Bergamo	Bergamo	NNP
cord-312486-rumqopg0	352	6	further	further	JJ
cord-312486-rumqopg0	352	7	reports	report	NNS
cord-312486-rumqopg0	352	8	of	of	IN
cord-312486-rumqopg0	352	9	similar	similar	JJ
cord-312486-rumqopg0	352	10	cases	case	NNS
cord-312486-rumqopg0	352	11	from	from	IN
cord-312486-rumqopg0	352	12	many	many	JJ
cord-312486-rumqopg0	352	13	countries	country	NNS
cord-312486-rumqopg0	352	14	have	have	VBP
cord-312486-rumqopg0	352	15	been	be	VBN
cord-312486-rumqopg0	352	16	published	publish	VBN
cord-312486-rumqopg0	352	17	[	[	-LRB-
cord-312486-rumqopg0	352	18	159	159	CD
cord-312486-rumqopg0	352	19	]	]	-RRB-
cord-312486-rumqopg0	352	20	[	[	-LRB-
cord-312486-rumqopg0	352	21	160	160	CD
cord-312486-rumqopg0	352	22	]	]	-RRB-
cord-312486-rumqopg0	352	23	[	[	-LRB-
cord-312486-rumqopg0	352	24	161	161	CD
cord-312486-rumqopg0	352	25	]	]	-RRB-
cord-312486-rumqopg0	352	26	[	[	-LRB-
cord-312486-rumqopg0	352	27	162	162	CD
cord-312486-rumqopg0	352	28	]	]	-RRB-
cord-312486-rumqopg0	352	29	[	[	-LRB-
cord-312486-rumqopg0	352	30	163	163	CD
cord-312486-rumqopg0	352	31	]	]	-RRB-
cord-312486-rumqopg0	352	32	.	.	.
cord-312486-rumqopg0	353	1	With	with	IN
cord-312486-rumqopg0	353	2	approximately	approximately	RB
cord-312486-rumqopg0	353	3	1,000	1,000	CD
cord-312486-rumqopg0	353	4	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	353	5	-	-	HYPH
cord-312486-rumqopg0	353	6	like	like	JJ
cord-312486-rumqopg0	353	7	cases	case	NNS
cord-312486-rumqopg0	353	8	reported	report	VBN
cord-312486-rumqopg0	353	9	,	,	,
cord-312486-rumqopg0	353	10	these	these	DT
cord-312486-rumqopg0	353	11	studies	study	NNS
cord-312486-rumqopg0	353	12	provide	provide	VBP
cord-312486-rumqopg0	353	13	a	a	DT
cord-312486-rumqopg0	353	14	consistent	consistent	JJ
cord-312486-rumqopg0	353	15	clinical	clinical	JJ
cord-312486-rumqopg0	353	16	picture	picture	NN
cord-312486-rumqopg0	353	17	:	:	:
cord-312486-rumqopg0	353	18	the	the	DT
cord-312486-rumqopg0	353	19	disease	disease	NN
cord-312486-rumqopg0	353	20	appears	appear	VBZ
cord-312486-rumqopg0	353	21	2	2	CD
cord-312486-rumqopg0	353	22	-	-	SYM
cord-312486-rumqopg0	353	23	4	4	CD
cord-312486-rumqopg0	353	24	weeks	week	NNS
cord-312486-rumqopg0	353	25	after	after	IN
cord-312486-rumqopg0	353	26	an	an	DT
cord-312486-rumqopg0	353	27	infection	infection	NN
cord-312486-rumqopg0	353	28	with	with	IN
cord-312486-rumqopg0	353	29	SARS	SARS	NNP
cord-312486-rumqopg0	353	30	-	-	HYPH
cord-312486-rumqopg0	353	31	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	353	32	and	and	CC
cord-312486-rumqopg0	353	33	most	most	JJS
cord-312486-rumqopg0	353	34	patients	patient	NNS
cord-312486-rumqopg0	353	35	have	have	VBP
cord-312486-rumqopg0	353	36	serological	serological	JJ
cord-312486-rumqopg0	353	37	evidence	evidence	NN
cord-312486-rumqopg0	353	38	of	of	IN
cord-312486-rumqopg0	353	39	infection	infection	NN
cord-312486-rumqopg0	353	40	;	;	:
cord-312486-rumqopg0	353	41	patients	patient	NNS
cord-312486-rumqopg0	353	42	are	be	VBP
cord-312486-rumqopg0	353	43	on	on	IN
cord-312486-rumqopg0	353	44	average	average	JJ
cord-312486-rumqopg0	353	45	older	old	JJR
cord-312486-rumqopg0	353	46	than	than	IN
cord-312486-rumqopg0	353	47	those	those	DT
cord-312486-rumqopg0	353	48	with	with	IN
cord-312486-rumqopg0	353	49	classical	classical	JJ
cord-312486-rumqopg0	353	50	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	353	51	disease	disease	NN
cord-312486-rumqopg0	353	52	;	;	:
cord-312486-rumqopg0	353	53	patients	patient	NNS
cord-312486-rumqopg0	353	54	experience	experience	VBP
cord-312486-rumqopg0	353	55	respiratory	respiratory	JJ
cord-312486-rumqopg0	353	56	and	and	CC
cord-312486-rumqopg0	353	57	gastrointestinal	gastrointestinal	JJ
cord-312486-rumqopg0	353	58	involvement	involvement	NN
cord-312486-rumqopg0	353	59	;	;	:
cord-312486-rumqopg0	353	60	signs	sign	NNS
cord-312486-rumqopg0	353	61	of	of	IN
cord-312486-rumqopg0	353	62	hemodynamic	hemodynamic	JJ
cord-312486-rumqopg0	353	63	instability	instability	NN
cord-312486-rumqopg0	353	64	;	;	:
cord-312486-rumqopg0	353	65	greater	great	JJR
cord-312486-rumqopg0	353	66	incidence	incidence	NN
cord-312486-rumqopg0	353	67	of	of	IN
cord-312486-rumqopg0	353	68	myocardial	myocardial	JJ
cord-312486-rumqopg0	353	69	injury	injury	NN
cord-312486-rumqopg0	353	70	;	;	:
cord-312486-rumqopg0	353	71	and	and	CC
cord-312486-rumqopg0	353	72	more	more	RBR
cord-312486-rumqopg0	353	73	intense	intense	JJ
cord-312486-rumqopg0	353	74	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	353	75	response	response	NN
cord-312486-rumqopg0	353	76	due	due	IN
cord-312486-rumqopg0	353	77	to	to	IN
cord-312486-rumqopg0	353	78	dysregulated	dysregulated	JJ
cord-312486-rumqopg0	353	79	immune	immune	JJ
cord-312486-rumqopg0	353	80	response	response	NN
cord-312486-rumqopg0	353	81	.	.	.
cord-312486-rumqopg0	354	1	The	the	DT
cord-312486-rumqopg0	354	2	incidence	incidence	NN
cord-312486-rumqopg0	354	3	of	of	IN
cord-312486-rumqopg0	354	4	coronary	coronary	JJ
cord-312486-rumqopg0	354	5	aneurism	aneurism	NN
cord-312486-rumqopg0	354	6	is	be	VBZ
cord-312486-rumqopg0	354	7	lower	low	JJR
cord-312486-rumqopg0	354	8	than	than	IN
cord-312486-rumqopg0	354	9	in	in	IN
cord-312486-rumqopg0	354	10	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	354	11	disease	disease	NN
cord-312486-rumqopg0	354	12	,	,	,
cord-312486-rumqopg0	354	13	but	but	CC
cord-312486-rumqopg0	354	14	this	this	DT
cord-312486-rumqopg0	354	15	may	may	MD
cord-312486-rumqopg0	354	16	be	be	VB
cord-312486-rumqopg0	354	17	a	a	DT
cord-312486-rumqopg0	354	18	consequence	consequence	NN
cord-312486-rumqopg0	354	19	of	of	IN
cord-312486-rumqopg0	354	20	relatively	relatively	RB
cord-312486-rumqopg0	354	21	short	short	JJ
cord-312486-rumqopg0	354	22	follow	follow	NN
cord-312486-rumqopg0	354	23	up	up	RP
cord-312486-rumqopg0	354	24	.	.	.
cord-312486-rumqopg0	355	1	Most	Most	JJS
cord-312486-rumqopg0	355	2	patients	patient	NNS
cord-312486-rumqopg0	355	3	so	so	RB
cord-312486-rumqopg0	355	4	far	far	RB
cord-312486-rumqopg0	355	5	have	have	VBP
cord-312486-rumqopg0	355	6	responded	respond	VBN
cord-312486-rumqopg0	355	7	well	well	RB
cord-312486-rumqopg0	355	8	to	to	IN
cord-312486-rumqopg0	355	9	the	the	DT
cord-312486-rumqopg0	355	10	same	same	JJ
cord-312486-rumqopg0	355	11	therapies	therapy	NNS
cord-312486-rumqopg0	355	12	used	use	VBN
cord-312486-rumqopg0	355	13	for	for	IN
cord-312486-rumqopg0	355	14	classical	classical	JJ
cord-312486-rumqopg0	355	15	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	355	16	disease	disease	NN
cord-312486-rumqopg0	355	17	.	.	.
cord-312486-rumqopg0	356	1	All	all	PDT
cord-312486-rumqopg0	356	2	these	these	DT
cord-312486-rumqopg0	356	3	results	result	NNS
cord-312486-rumqopg0	356	4	and	and	CC
cord-312486-rumqopg0	356	5	considerations	consideration	NNS
cord-312486-rumqopg0	356	6	support	support	VBP
cord-312486-rumqopg0	356	7	the	the	DT
cord-312486-rumqopg0	356	8	notion	notion	NN
cord-312486-rumqopg0	356	9	that	that	IN
cord-312486-rumqopg0	356	10	the	the	DT
cord-312486-rumqopg0	356	11	immune	immune	JJ
cord-312486-rumqopg0	356	12	response	response	NN
cord-312486-rumqopg0	356	13	to	to	IN
cord-312486-rumqopg0	356	14	SARS	SARS	NNP
cord-312486-rumqopg0	356	15	-	-	HYPH
cord-312486-rumqopg0	356	16	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	356	17	is	be	VBZ
cord-312486-rumqopg0	356	18	responsible	responsible	JJ
cord-312486-rumqopg0	356	19	for	for	IN
cord-312486-rumqopg0	356	20	this	this	DT
cord-312486-rumqopg0	356	21	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	356	22	-	-	HYPH
cord-312486-rumqopg0	356	23	like	like	JJ
cord-312486-rumqopg0	356	24	disease	disease	NN
cord-312486-rumqopg0	356	25	[	[	-LRB-
cord-312486-rumqopg0	356	26	158	158	CD
cord-312486-rumqopg0	356	27	,	,	,
cord-312486-rumqopg0	356	28	163	163	CD
cord-312486-rumqopg0	356	29	]	]	-RRB-
cord-312486-rumqopg0	356	30	in	in	IN
cord-312486-rumqopg0	356	31	susceptible	susceptible	JJ
cord-312486-rumqopg0	356	32	patients	patient	NNS
cord-312486-rumqopg0	356	33	.	.	.
cord-312486-rumqopg0	357	1	U.K.	U.K.	NNP
cord-312486-rumqopg0	357	2	pediatricians	pediatrician	NNS
cord-312486-rumqopg0	357	3	and	and	CC
cord-312486-rumqopg0	357	4	their	-PRON-	PRP$
cord-312486-rumqopg0	357	5	National	National	NNP
cord-312486-rumqopg0	357	6	Health	Health	NNP
cord-312486-rumqopg0	357	7	Service	Service	NNP
cord-312486-rumqopg0	357	8	defined	define	VBD
cord-312486-rumqopg0	357	9	and	and	CC
cord-312486-rumqopg0	357	10	named	name	VBD
cord-312486-rumqopg0	357	11	the	the	DT
cord-312486-rumqopg0	357	12	‗new	‗new	NNP
cord-312486-rumqopg0	357	13	'	'	''
cord-312486-rumqopg0	357	14	,	,	,
cord-312486-rumqopg0	357	15	disease	disease	NN
cord-312486-rumqopg0	357	16	-pediatric	-pediatric	DT
cord-312486-rumqopg0	357	17	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	357	18	multisystem	multisystem	JJ
cord-312486-rumqopg0	357	19	syndrome	syndrome	NN
cord-312486-rumqopg0	357	20	temporally	temporally	RB
cord-312486-rumqopg0	357	21	associated	associate	VBN
cord-312486-rumqopg0	357	22	with	with	IN
cord-312486-rumqopg0	357	23	severe	severe	JJ
cord-312486-rumqopg0	357	24	acute	acute	JJ
cord-312486-rumqopg0	357	25	respiratory	respiratory	JJ
cord-312486-rumqopg0	357	26	syndrome	syndrome	NN
cord-312486-rumqopg0	357	27	coronavirus	coronavirus	NN
cord-312486-rumqopg0	357	28	2	2	CD
cord-312486-rumqopg0	358	1	(	(	-LRB-
cord-312486-rumqopg0	358	2	SARS	SARS	NNP
cord-312486-rumqopg0	358	3	-	-	HYPH
cord-312486-rumqopg0	358	4	CoV-2),‖	CoV-2),‖	NNP
cord-312486-rumqopg0	359	1	or	or	CC
cord-312486-rumqopg0	359	2	PIMS	PIMS	NNP
cord-312486-rumqopg0	359	3	-	-	HYPH
cord-312486-rumqopg0	359	4	TS	TS	NNP
cord-312486-rumqopg0	359	5	[	[	-LRB-
cord-312486-rumqopg0	359	6	159	159	CD
cord-312486-rumqopg0	359	7	]	]	-RRB-
cord-312486-rumqopg0	359	8	.	.	.
cord-312486-rumqopg0	360	1	The	the	DT
cord-312486-rumqopg0	360	2	CDC	CDC	NNP
cord-312486-rumqopg0	360	3	in	in	IN
cord-312486-rumqopg0	360	4	the	the	DT
cord-312486-rumqopg0	360	5	U.S.	U.S.	NNP
cord-312486-rumqopg0	360	6	and	and	CC
cord-312486-rumqopg0	360	7	the	the	DT
cord-312486-rumqopg0	360	8	WHO	who	WP
cord-312486-rumqopg0	360	9	subsequently	subsequently	RB
cord-312486-rumqopg0	360	10	published	publish	VBD
cord-312486-rumqopg0	360	11	their	-PRON-	PRP$
cord-312486-rumqopg0	360	12	own	own	JJ
cord-312486-rumqopg0	360	13	differing	differing	JJ
cord-312486-rumqopg0	360	14	definitions	definition	NNS
cord-312486-rumqopg0	360	15	of	of	IN
cord-312486-rumqopg0	360	16	the	the	DT
cord-312486-rumqopg0	360	17	disorder	disorder	NN
cord-312486-rumqopg0	360	18	,	,	,
cord-312486-rumqopg0	360	19	which	which	WDT
cord-312486-rumqopg0	360	20	they	-PRON-	PRP
cord-312486-rumqopg0	360	21	termed	term	VBD
cord-312486-rumqopg0	360	22	multisystem	multisystem	JJ
cord-312486-rumqopg0	360	23	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	360	24	syndrome	syndrome	NN
cord-312486-rumqopg0	360	25	in	in	IN
cord-312486-rumqopg0	360	26	children	child	NNS
cord-312486-rumqopg0	360	27	(	(	-LRB-
cord-312486-rumqopg0	360	28	MIS	MIS	NNP
cord-312486-rumqopg0	360	29	-	-	HYPH
cord-312486-rumqopg0	360	30	C	C	NNP
cord-312486-rumqopg0	360	31	)	)	-RRB-
cord-312486-rumqopg0	360	32	[	[	-LRB-
cord-312486-rumqopg0	360	33	160	160	CD
cord-312486-rumqopg0	360	34	]	]	-RRB-
cord-312486-rumqopg0	360	35	[	[	-LRB-
cord-312486-rumqopg0	360	36	161	161	CD
cord-312486-rumqopg0	360	37	]	]	-RRB-
cord-312486-rumqopg0	360	38	[	[	-LRB-
cord-312486-rumqopg0	360	39	162	162	CD
cord-312486-rumqopg0	360	40	]	]	-RRB-
cord-312486-rumqopg0	360	41	[	[	-LRB-
cord-312486-rumqopg0	360	42	163	163	CD
cord-312486-rumqopg0	360	43	]	]	-RRB-
cord-312486-rumqopg0	360	44	.	.	.
cord-312486-rumqopg0	361	1	Physicians	physician	NNS
cord-312486-rumqopg0	361	2	and	and	CC
cord-312486-rumqopg0	361	3	scientists	scientist	NNS
cord-312486-rumqopg0	361	4	in	in	IN
cord-312486-rumqopg0	361	5	the	the	DT
cord-312486-rumqopg0	361	6	field	field	NN
cord-312486-rumqopg0	361	7	of	of	IN
cord-312486-rumqopg0	361	8	biology	biology	NN
cord-312486-rumqopg0	361	9	are	be	VBP
cord-312486-rumqopg0	361	10	prone	prone	JJ
cord-312486-rumqopg0	361	11	to	to	IN
cord-312486-rumqopg0	361	12	giving	give	VBG
cord-312486-rumqopg0	361	13	names	name	NNS
cord-312486-rumqopg0	361	14	that	that	WDT
cord-312486-rumqopg0	361	15	are	be	VBP
cord-312486-rumqopg0	361	16	often	often	RB
cord-312486-rumqopg0	361	17	more	more	RBR
cord-312486-rumqopg0	361	18	confusing	confusing	JJ
cord-312486-rumqopg0	361	19	than	than	IN
cord-312486-rumqopg0	361	20	helpful	helpful	JJ
cord-312486-rumqopg0	361	21	.	.	.
cord-312486-rumqopg0	362	1	I	-PRON-	PRP
cord-312486-rumqopg0	362	2	have	have	VBP
cord-312486-rumqopg0	362	3	worked	work	VBN
cord-312486-rumqopg0	362	4	for	for	IN
cord-312486-rumqopg0	362	5	some	some	DT
cord-312486-rumqopg0	362	6	years	year	NNS
cord-312486-rumqopg0	362	7	on	on	IN
cord-312486-rumqopg0	362	8	a	a	DT
cord-312486-rumqopg0	362	9	cytokine	cytokine	NN
cord-312486-rumqopg0	362	10	named	name	VBN
cord-312486-rumqopg0	362	11	tumor	tumor	NN
cord-312486-rumqopg0	362	12	necrosis	necrosis	NN
cord-312486-rumqopg0	362	13	factor	factor	NN
cord-312486-rumqopg0	362	14	(	(	-LRB-
cord-312486-rumqopg0	362	15	TNF	TNF	NNP
cord-312486-rumqopg0	362	16	)	)	-RRB-
cord-312486-rumqopg0	362	17	that	that	WDT
cord-312486-rumqopg0	362	18	had	have	VBD
cord-312486-rumqopg0	362	19	practically	practically	RB
cord-312486-rumqopg0	362	20	nothing	nothing	NN
cord-312486-rumqopg0	362	21	to	to	TO
cord-312486-rumqopg0	362	22	do	do	VB
cord-312486-rumqopg0	362	23	with	with	IN
cord-312486-rumqopg0	362	24	necrosis	necrosis	NN
cord-312486-rumqopg0	362	25	of	of	IN
cord-312486-rumqopg0	362	26	tumors	tumor	NNS
cord-312486-rumqopg0	362	27	,	,	,
cord-312486-rumqopg0	362	28	and	and	CC
cord-312486-rumqopg0	362	29	from	from	IN
cord-312486-rumqopg0	362	30	any	any	DT
cord-312486-rumqopg0	362	31	sensible	sensible	JJ
cord-312486-rumqopg0	362	32	perspective	perspective	NN
cord-312486-rumqopg0	362	33	is	be	VBZ
cord-312486-rumqopg0	362	34	as	as	RB
cord-312486-rumqopg0	362	35	much	much	JJ
cord-312486-rumqopg0	362	36	an	an	DT
cord-312486-rumqopg0	362	37	interleukin	interleukin	NN
cord-312486-rumqopg0	362	38	(	(	-LRB-
cord-312486-rumqopg0	362	39	IL	IL	NNP
cord-312486-rumqopg0	362	40	)	)	-RRB-
cord-312486-rumqopg0	362	41	as	as	IN
cord-312486-rumqopg0	362	42	any	any	DT
cord-312486-rumqopg0	362	43	of	of	IN
cord-312486-rumqopg0	362	44	the	the	DT
cord-312486-rumqopg0	362	45	approximately	approximately	RB
cord-312486-rumqopg0	362	46	50	50	CD
cord-312486-rumqopg0	362	47	ILs	il	NNS
cord-312486-rumqopg0	362	48	.	.	.
cord-312486-rumqopg0	363	1	I	-PRON-	PRP
cord-312486-rumqopg0	363	2	am	be	VBP
cord-312486-rumqopg0	363	3	not	not	RB
cord-312486-rumqopg0	363	4	aware	aware	JJ
cord-312486-rumqopg0	363	5	of	of	IN
cord-312486-rumqopg0	363	6	any	any	DT
cord-312486-rumqopg0	363	7	clinical	clinical	JJ
cord-312486-rumqopg0	363	8	,	,	,
cord-312486-rumqopg0	363	9	therapeutic	therapeutic	JJ
cord-312486-rumqopg0	363	10	,	,	,
cord-312486-rumqopg0	363	11	or	or	CC
cord-312486-rumqopg0	363	12	long	long	JJ
cord-312486-rumqopg0	363	13	term	term	NN
cord-312486-rumqopg0	363	14	follow	follow	VB
cord-312486-rumqopg0	363	15	up	up	RP
cord-312486-rumqopg0	363	16	consideration	consideration	NN
cord-312486-rumqopg0	363	17	that	that	WDT
cord-312486-rumqopg0	363	18	would	would	MD
cord-312486-rumqopg0	363	19	benefit	benefit	VB
cord-312486-rumqopg0	363	20	from	from	IN
cord-312486-rumqopg0	363	21	a	a	DT
cord-312486-rumqopg0	363	22	more	more	RBR
cord-312486-rumqopg0	363	23	nuanced	nuanced	JJ
cord-312486-rumqopg0	363	24	definition	definition	NN
cord-312486-rumqopg0	363	25	and	and	CC
cord-312486-rumqopg0	363	26	naming	naming	NN
cord-312486-rumqopg0	363	27	such	such	JJ
cord-312486-rumqopg0	363	28	as	as	IN
cord-312486-rumqopg0	363	29	PIMS	PIMS	NNP
cord-312486-rumqopg0	363	30	-	-	HYPH
cord-312486-rumqopg0	363	31	TS	TS	NNP
cord-312486-rumqopg0	363	32	or	or	CC
cord-312486-rumqopg0	363	33	MIS	MIS	NNP
cord-312486-rumqopg0	363	34	-	-	HYPH
cord-312486-rumqopg0	363	35	C	C	NNP
cord-312486-rumqopg0	363	36	,	,	,
cord-312486-rumqopg0	363	37	rather	rather	RB
cord-312486-rumqopg0	363	38	than	than	IN
cord-312486-rumqopg0	363	39	simply	simply	RB
cord-312486-rumqopg0	363	40	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	363	41	-	-	HYPH
cord-312486-rumqopg0	363	42	like	like	JJ
cord-312486-rumqopg0	363	43	disease	disease	NN
cord-312486-rumqopg0	363	44	.	.	.
cord-312486-rumqopg0	364	1	In	in	IN
cord-312486-rumqopg0	364	2	fact	fact	NN
cord-312486-rumqopg0	364	3	some	some	DT
cord-312486-rumqopg0	364	4	authors	author	NNS
cord-312486-rumqopg0	364	5	agree	agree	VBP
cord-312486-rumqopg0	364	6	that	that	IN
cord-312486-rumqopg0	364	7	-until	-until	IN
cord-312486-rumqopg0	364	8	more	more	JJR
cord-312486-rumqopg0	364	9	is	be	VBZ
cord-312486-rumqopg0	364	10	known	know	VBN
cord-312486-rumqopg0	364	11	about	about	IN
cord-312486-rumqopg0	364	12	long	long	JJ
cord-312486-rumqopg0	364	13	-	-	HYPH
cord-312486-rumqopg0	364	14	term	term	NN
cord-312486-rumqopg0	364	15	cardiac	cardiac	JJ
cord-312486-rumqopg0	364	16	sequalae	sequalae	NNS
cord-312486-rumqopg0	364	17	of	of	IN
cord-312486-rumqopg0	364	18	MIS	MIS	NNP
cord-312486-rumqopg0	364	19	-	-	HYPH
cord-312486-rumqopg0	364	20	C	C	NNP
cord-312486-rumqopg0	364	21	,	,	,
cord-312486-rumqopg0	364	22	providers	provider	NNS
cord-312486-rumqopg0	364	23	should	should	MD
cord-312486-rumqopg0	364	24	consider	consider	VB
cord-312486-rumqopg0	364	25	following	follow	VBG
cord-312486-rumqopg0	364	26	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	364	27	disease	disease	NN
cord-312486-rumqopg0	364	28	guidelines	guideline	NNS
cord-312486-rumqopg0	364	29	for	for	IN
cord-312486-rumqopg0	364	30	follow	follow	VB
cord-312486-rumqopg0	364	31	up‖	up‖	NNP
cord-312486-rumqopg0	364	32	[	[	-LRB-
cord-312486-rumqopg0	364	33	161	161	CD
cord-312486-rumqopg0	364	34	]	]	-RRB-
cord-312486-rumqopg0	364	35	.	.	.
cord-312486-rumqopg0	365	1	Until	until	IN
cord-312486-rumqopg0	365	2	a	a	DT
cord-312486-rumqopg0	365	3	much	much	RB
cord-312486-rumqopg0	365	4	better	well	JJR
cord-312486-rumqopg0	365	5	understanding	understanding	NN
cord-312486-rumqopg0	365	6	of	of	IN
cord-312486-rumqopg0	365	7	the	the	DT
cord-312486-rumqopg0	365	8	pathogenesis	pathogenesis	NN
cord-312486-rumqopg0	365	9	of	of	IN
cord-312486-rumqopg0	365	10	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	365	11	disease	disease	NN
cord-312486-rumqopg0	365	12	and	and	CC
cord-312486-rumqopg0	365	13	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	365	14	-	-	HYPH
cord-312486-rumqopg0	365	15	like	like	JJ
cord-312486-rumqopg0	365	16	disease	disease	NN
cord-312486-rumqopg0	365	17	emerges	emerge	VBZ
cord-312486-rumqopg0	365	18	,	,	,
cord-312486-rumqopg0	365	19	I	-PRON-	PRP
cord-312486-rumqopg0	365	20	do	do	VBP
cord-312486-rumqopg0	365	21	not	not	RB
cord-312486-rumqopg0	365	22	see	see	VB
cord-312486-rumqopg0	365	23	a	a	DT
cord-312486-rumqopg0	365	24	reason	reason	NN
cord-312486-rumqopg0	365	25	to	to	TO
cord-312486-rumqopg0	365	26	further	further	RB
cord-312486-rumqopg0	365	27	confuse	confuse	VB
cord-312486-rumqopg0	365	28	the	the	DT
cord-312486-rumqopg0	365	29	literature	literature	NN
cord-312486-rumqopg0	365	30	.	.	.
cord-312486-rumqopg0	366	1	As	as	IN
cord-312486-rumqopg0	366	2	I	-PRON-	PRP
cord-312486-rumqopg0	366	3	am	be	VBP
cord-312486-rumqopg0	366	4	writing	write	VBG
cord-312486-rumqopg0	366	5	this	this	DT
cord-312486-rumqopg0	366	6	essay	essay	NN
cord-312486-rumqopg0	366	7	,	,	,
cord-312486-rumqopg0	366	8	the	the	DT
cord-312486-rumqopg0	366	9	pandemic	pandemic	NN
cord-312486-rumqopg0	366	10	seems	seem	VBZ
cord-312486-rumqopg0	366	11	far	far	RB
cord-312486-rumqopg0	366	12	from	from	IN
cord-312486-rumqopg0	366	13	being	be	VBG
cord-312486-rumqopg0	366	14	over	over	RB
cord-312486-rumqopg0	366	15	.	.	.
cord-312486-rumqopg0	367	1	It	-PRON-	PRP
cord-312486-rumqopg0	367	2	surely	surely	RB
cord-312486-rumqopg0	367	3	looks	look	VBZ
cord-312486-rumqopg0	367	4	like	like	IN
cord-312486-rumqopg0	367	5	we	-PRON-	PRP
cord-312486-rumqopg0	367	6	are	be	VBP
cord-312486-rumqopg0	367	7	not	not	RB
cord-312486-rumqopg0	367	8	even	even	RB
cord-312486-rumqopg0	367	9	in	in	IN
cord-312486-rumqopg0	367	10	the	the	DT
cord-312486-rumqopg0	367	11	end	end	NN
cord-312486-rumqopg0	367	12	of	of	IN
cord-312486-rumqopg0	367	13	the	the	DT
cord-312486-rumqopg0	367	14	beginning	beginning	NN
cord-312486-rumqopg0	367	15	.	.	.
cord-312486-rumqopg0	368	1	The	the	DT
cord-312486-rumqopg0	368	2	long	long	JJ
cord-312486-rumqopg0	368	3	-	-	HYPH
cord-312486-rumqopg0	368	4	term	term	NN
cord-312486-rumqopg0	368	5	impact	impact	NN
cord-312486-rumqopg0	368	6	of	of	IN
cord-312486-rumqopg0	368	7	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	368	8	is	be	VBZ
cord-312486-rumqopg0	368	9	too	too	RB
cord-312486-rumqopg0	368	10	early	early	JJ
cord-312486-rumqopg0	368	11	to	to	TO
cord-312486-rumqopg0	368	12	evaluate	evaluate	VB
cord-312486-rumqopg0	368	13	.	.	.
cord-312486-rumqopg0	369	1	Patients	patient	NNS
cord-312486-rumqopg0	369	2	who	who	WP
cord-312486-rumqopg0	369	3	have	have	VBP
cord-312486-rumqopg0	369	4	recovered	recover	VBN
cord-312486-rumqopg0	369	5	from	from	IN
cord-312486-rumqopg0	369	6	the	the	DT
cord-312486-rumqopg0	369	7	disease	disease	NN
cord-312486-rumqopg0	369	8	report	report	NN
cord-312486-rumqopg0	369	9	lingering	linger	VBG
cord-312486-rumqopg0	369	10	chronic	chronic	JJ
cord-312486-rumqopg0	369	11	fatigue	fatigue	NN
cord-312486-rumqopg0	369	12	,	,	,
cord-312486-rumqopg0	369	13	muscle	muscle	NN
cord-312486-rumqopg0	369	14	weakness	weakness	NN
cord-312486-rumqopg0	369	15	,	,	,
cord-312486-rumqopg0	369	16	loss	loss	NN
cord-312486-rumqopg0	369	17	of	of	IN
cord-312486-rumqopg0	369	18	sense	sense	NN
cord-312486-rumqopg0	369	19	of	of	IN
cord-312486-rumqopg0	369	20	smell	smell	NN
cord-312486-rumqopg0	369	21	,	,	,
cord-312486-rumqopg0	369	22	and	and	CC
cord-312486-rumqopg0	369	23	difficulties	difficulty	NNS
cord-312486-rumqopg0	369	24	in	in	IN
cord-312486-rumqopg0	369	25	concentration	concentration	NN
cord-312486-rumqopg0	369	26	.	.	.
cord-312486-rumqopg0	370	1	But	but	CC
cord-312486-rumqopg0	370	2	this	this	DT
cord-312486-rumqopg0	370	3	might	may	MD
cord-312486-rumqopg0	370	4	be	be	VB
cord-312486-rumqopg0	370	5	just	just	RB
cord-312486-rumqopg0	370	6	the	the	DT
cord-312486-rumqopg0	370	7	tip	tip	NN
cord-312486-rumqopg0	370	8	of	of	IN
cord-312486-rumqopg0	370	9	the	the	DT
cord-312486-rumqopg0	370	10	iceberg	iceberg	NN
cord-312486-rumqopg0	370	11	.	.	.
cord-312486-rumqopg0	371	1	We	-PRON-	PRP
cord-312486-rumqopg0	371	2	already	already	RB
cord-312486-rumqopg0	371	3	know	know	VBP
cord-312486-rumqopg0	371	4	that	that	IN
cord-312486-rumqopg0	371	5	impaired	impair	VBN
cord-312486-rumqopg0	371	6	liver	liver	NN
cord-312486-rumqopg0	371	7	function	function	NN
cord-312486-rumqopg0	371	8	continues	continue	VBZ
cord-312486-rumqopg0	371	9	for	for	IN
cord-312486-rumqopg0	371	10	some	some	DT
cord-312486-rumqopg0	371	11	time	time	NN
cord-312486-rumqopg0	371	12	after	after	IN
cord-312486-rumqopg0	371	13	patients	patient	NNS
cord-312486-rumqopg0	371	14	have	have	VBP
cord-312486-rumqopg0	371	15	apparently	apparently	RB
cord-312486-rumqopg0	371	16	recovered	recover	VBN
cord-312486-rumqopg0	371	17	and	and	CC
cord-312486-rumqopg0	371	18	the	the	DT
cord-312486-rumqopg0	371	19	virus	virus	NN
cord-312486-rumqopg0	371	20	has	have	VBZ
cord-312486-rumqopg0	371	21	cleared	clear	VBN
cord-312486-rumqopg0	371	22	.	.	.
cord-312486-rumqopg0	372	1	It	-PRON-	PRP
cord-312486-rumqopg0	372	2	is	be	VBZ
cord-312486-rumqopg0	372	3	also	also	RB
cord-312486-rumqopg0	372	4	probable	probable	JJ
cord-312486-rumqopg0	372	5	that	that	IN
cord-312486-rumqopg0	372	6	some	some	DT
cord-312486-rumqopg0	372	7	patients	patient	NNS
cord-312486-rumqopg0	372	8	will	will	MD
cord-312486-rumqopg0	372	9	have	have	VB
cord-312486-rumqopg0	372	10	lasting	last	VBG
cord-312486-rumqopg0	372	11	pulmonary	pulmonary	JJ
cord-312486-rumqopg0	372	12	damage	damage	NN
cord-312486-rumqopg0	372	13	due	due	IN
cord-312486-rumqopg0	372	14	to	to	IN
cord-312486-rumqopg0	372	15	fibrosis	fibrosis	NN
cord-312486-rumqopg0	372	16	as	as	IN
cord-312486-rumqopg0	372	17	has	have	VBZ
cord-312486-rumqopg0	372	18	been	be	VBN
cord-312486-rumqopg0	372	19	documented	document	VBN
cord-312486-rumqopg0	372	20	in	in	IN
cord-312486-rumqopg0	372	21	about	about	RB
cord-312486-rumqopg0	372	22	25	25	CD
cord-312486-rumqopg0	372	23	%	%	NN
cord-312486-rumqopg0	372	24	of	of	IN
cord-312486-rumqopg0	372	25	patients	patient	NNS
cord-312486-rumqopg0	372	26	recovered	recover	VBN
cord-312486-rumqopg0	372	27	form	form	NN
cord-312486-rumqopg0	372	28	SARS	SARS	NNP
cord-312486-rumqopg0	372	29	[	[	-LRB-
cord-312486-rumqopg0	372	30	164	164	CD
cord-312486-rumqopg0	372	31	]	]	-RRB-
cord-312486-rumqopg0	372	32	.	.	.
cord-312486-rumqopg0	373	1	Similarly	similarly	RB
cord-312486-rumqopg0	373	2	,	,	,
cord-312486-rumqopg0	373	3	myocardial	myocardial	JJ
cord-312486-rumqopg0	373	4	J	J	NNP
cord-312486-rumqopg0	373	5	o	o	NN
cord-312486-rumqopg0	373	6	u	u	NN
cord-312486-rumqopg0	373	7	r	r	NN
cord-312486-rumqopg0	373	8	n	n	NN
cord-312486-rumqopg0	373	9	a	a	DT
cord-312486-rumqopg0	373	10	l	l	NN
cord-312486-rumqopg0	373	11	P	p	NN
cord-312486-rumqopg0	373	12	r	r	NN
cord-312486-rumqopg0	373	13	e	e	NN
cord-312486-rumqopg0	373	14	-p	-p	NN
cord-312486-rumqopg0	373	15	r	r	NN
cord-312486-rumqopg0	373	16	o	o	NN
cord-312486-rumqopg0	373	17	o	o	NN
cord-312486-rumqopg0	374	1	f	f	LS
cord-312486-rumqopg0	374	2	scarring	scarring	NN
cord-312486-rumqopg0	374	3	will	will	MD
cord-312486-rumqopg0	374	4	cause	cause	VB
cord-312486-rumqopg0	374	5	cardiac	cardiac	JJ
cord-312486-rumqopg0	374	6	impairment	impairment	NN
cord-312486-rumqopg0	374	7	in	in	IN
cord-312486-rumqopg0	374	8	certain	certain	JJ
cord-312486-rumqopg0	374	9	COVID-19	covid-19	NN
cord-312486-rumqopg0	374	10	recovered	recovered	JJ
cord-312486-rumqopg0	374	11	patients	patient	NNS
cord-312486-rumqopg0	374	12	.	.	.
cord-312486-rumqopg0	375	1	Moreover	moreover	RB
cord-312486-rumqopg0	375	2	,	,	,
cord-312486-rumqopg0	375	3	the	the	DT
cord-312486-rumqopg0	375	4	long	long	JJ
cord-312486-rumqopg0	375	5	-	-	HYPH
cord-312486-rumqopg0	375	6	term	term	NN
cord-312486-rumqopg0	375	7	consequences	consequence	NNS
cord-312486-rumqopg0	375	8	of	of	IN
cord-312486-rumqopg0	375	9	the	the	DT
cord-312486-rumqopg0	375	10	massive	massive	JJ
cord-312486-rumqopg0	375	11	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	375	12	response	response	NN
cord-312486-rumqopg0	375	13	affecting	affect	VBG
cord-312486-rumqopg0	375	14	many	many	JJ
cord-312486-rumqopg0	375	15	tissues	tissue	NNS
cord-312486-rumqopg0	375	16	,	,	,
cord-312486-rumqopg0	375	17	and	and	CC
cord-312486-rumqopg0	375	18	its	-PRON-	PRP$
cord-312486-rumqopg0	375	19	effect	effect	NN
cord-312486-rumqopg0	375	20	on	on	IN
cord-312486-rumqopg0	375	21	the	the	DT
cord-312486-rumqopg0	375	22	competence	competence	NN
cord-312486-rumqopg0	375	23	of	of	IN
cord-312486-rumqopg0	375	24	the	the	DT
cord-312486-rumqopg0	375	25	immune	immune	JJ
cord-312486-rumqopg0	375	26	system	system	NN
cord-312486-rumqopg0	375	27	itself	-PRON-	PRP
cord-312486-rumqopg0	375	28	,	,	,
cord-312486-rumqopg0	375	29	are	be	VBP
cord-312486-rumqopg0	375	30	unknown	unknown	JJ
cord-312486-rumqopg0	375	31	.	.	.
cord-312486-rumqopg0	376	1	It	-PRON-	PRP
cord-312486-rumqopg0	376	2	is	be	VBZ
cord-312486-rumqopg0	376	3	,	,	,
cord-312486-rumqopg0	376	4	however	however	RB
cord-312486-rumqopg0	376	5	,	,	,
cord-312486-rumqopg0	376	6	possible	possible	JJ
cord-312486-rumqopg0	376	7	that	that	IN
cord-312486-rumqopg0	376	8	the	the	DT
cord-312486-rumqopg0	376	9	intense	intense	JJ
cord-312486-rumqopg0	376	10	inflammation	inflammation	NN
cord-312486-rumqopg0	376	11	in	in	IN
cord-312486-rumqopg0	376	12	many	many	JJ
cord-312486-rumqopg0	376	13	tissues	tissue	NNS
cord-312486-rumqopg0	376	14	might	may	MD
cord-312486-rumqopg0	376	15	cause	cause	VB
cord-312486-rumqopg0	376	16	cellular	cellular	JJ
cord-312486-rumqopg0	376	17	damage	damage	NN
cord-312486-rumqopg0	376	18	and	and	CC
cord-312486-rumqopg0	376	19	exposure	exposure	NN
cord-312486-rumqopg0	376	20	of	of	IN
cord-312486-rumqopg0	376	21	self	self	NN
cord-312486-rumqopg0	376	22	-	-	HYPH
cord-312486-rumqopg0	376	23	antigens	antigen	NNS
cord-312486-rumqopg0	376	24	eliciting	elicit	VBG
cord-312486-rumqopg0	376	25	auto	auto	NN
cord-312486-rumqopg0	376	26	-	-	HYPH
cord-312486-rumqopg0	376	27	reactive	reactive	JJ
cord-312486-rumqopg0	376	28	T	t	NN
cord-312486-rumqopg0	376	29	and	and	CC
cord-312486-rumqopg0	376	30	B	b	NN
cord-312486-rumqopg0	376	31	cells	cell	NNS
cord-312486-rumqopg0	376	32	and	and	CC
cord-312486-rumqopg0	376	33	generating	generate	VBG
cord-312486-rumqopg0	376	34	an	an	DT
cord-312486-rumqopg0	376	35	autoimmune	autoimmune	JJ
cord-312486-rumqopg0	376	36	disease	disease	NN
cord-312486-rumqopg0	376	37	.	.	.
cord-312486-rumqopg0	377	1	Another	another	DT
cord-312486-rumqopg0	377	2	question	question	NN
cord-312486-rumqopg0	377	3	that	that	WDT
cord-312486-rumqopg0	377	4	could	could	MD
cord-312486-rumqopg0	377	5	take	take	VB
cord-312486-rumqopg0	377	6	years	year	NNS
cord-312486-rumqopg0	377	7	to	to	TO
cord-312486-rumqopg0	377	8	answer	answer	VB
cord-312486-rumqopg0	377	9	is	be	VBZ
cord-312486-rumqopg0	377	10	whether	whether	IN
cord-312486-rumqopg0	377	11	the	the	DT
cord-312486-rumqopg0	377	12	SARS	SARS	NNP
cord-312486-rumqopg0	377	13	-	-	HYPH
cord-312486-rumqopg0	377	14	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	377	15	virus	virus	NN
cord-312486-rumqopg0	377	16	may	may	MD
cord-312486-rumqopg0	377	17	lie	lie	VB
cord-312486-rumqopg0	377	18	dormant	dormant	JJ
cord-312486-rumqopg0	377	19	in	in	IN
cord-312486-rumqopg0	377	20	the	the	DT
cord-312486-rumqopg0	377	21	human	human	JJ
cord-312486-rumqopg0	377	22	body	body	NN
cord-312486-rumqopg0	377	23	for	for	IN
cord-312486-rumqopg0	377	24	years	year	NNS
cord-312486-rumqopg0	377	25	and	and	CC
cord-312486-rumqopg0	377	26	then	then	RB
cord-312486-rumqopg0	377	27	launch	launch	VB
cord-312486-rumqopg0	377	28	itself	-PRON-	PRP
cord-312486-rumqopg0	377	29	later	later	RB
cord-312486-rumqopg0	377	30	in	in	IN
cord-312486-rumqopg0	377	31	a	a	DT
cord-312486-rumqopg0	377	32	different	different	JJ
cord-312486-rumqopg0	377	33	form	form	NN
cord-312486-rumqopg0	377	34	.	.	.
cord-312486-rumqopg0	378	1	For	for	IN
cord-312486-rumqopg0	378	2	example	example	NN
cord-312486-rumqopg0	378	3	,	,	,
cord-312486-rumqopg0	378	4	after	after	IN
cord-312486-rumqopg0	378	5	a	a	DT
cord-312486-rumqopg0	378	6	chicken	chicken	NN
cord-312486-rumqopg0	378	7	pox	pox	NN
cord-312486-rumqopg0	378	8	infection	infection	NN
cord-312486-rumqopg0	378	9	,	,	,
cord-312486-rumqopg0	378	10	the	the	DT
cord-312486-rumqopg0	378	11	herpes	herpes	NNP
cord-312486-rumqopg0	378	12	virus	virus	NN
cord-312486-rumqopg0	378	13	that	that	WDT
cord-312486-rumqopg0	378	14	caused	cause	VBD
cord-312486-rumqopg0	378	15	the	the	DT
cord-312486-rumqopg0	378	16	illness	illness	NN
cord-312486-rumqopg0	378	17	reemerges	reemerge	VBZ
cord-312486-rumqopg0	378	18	after	after	IN
cord-312486-rumqopg0	378	19	decades	decade	NNS
cord-312486-rumqopg0	378	20	in	in	IN
cord-312486-rumqopg0	378	21	form	form	NN
cord-312486-rumqopg0	378	22	of	of	IN
cord-312486-rumqopg0	378	23	shingles	shingle	NNS
cord-312486-rumqopg0	378	24	.	.	.
cord-312486-rumqopg0	379	1	Similarly	similarly	RB
cord-312486-rumqopg0	379	2	the	the	DT
cord-312486-rumqopg0	379	3	hepatitis	hepatitis	NN
cord-312486-rumqopg0	379	4	B	B	NNP
cord-312486-rumqopg0	379	5	virus	virus	NN
cord-312486-rumqopg0	379	6	causes	cause	VBZ
cord-312486-rumqopg0	379	7	the	the	DT
cord-312486-rumqopg0	379	8	appearance	appearance	NN
cord-312486-rumqopg0	379	9	of	of	IN
cord-312486-rumqopg0	379	10	liver	liver	NN
cord-312486-rumqopg0	379	11	cancer	cancer	NN
cord-312486-rumqopg0	379	12	years	year	NNS
cord-312486-rumqopg0	379	13	later	later	RB
cord-312486-rumqopg0	379	14	.	.	.
cord-312486-rumqopg0	380	1	A	a	DT
cord-312486-rumqopg0	380	2	general	general	JJ
cord-312486-rumqopg0	380	3	comment	comment	NN
cord-312486-rumqopg0	380	4	is	be	VBZ
cord-312486-rumqopg0	380	5	pertinent	pertinent	JJ
cord-312486-rumqopg0	380	6	at	at	IN
cord-312486-rumqopg0	380	7	this	this	DT
cord-312486-rumqopg0	380	8	point	point	NN
cord-312486-rumqopg0	380	9	:	:	:
cord-312486-rumqopg0	380	10	the	the	DT
cord-312486-rumqopg0	380	11	culmination	culmination	NN
cord-312486-rumqopg0	380	12	of	of	IN
cord-312486-rumqopg0	380	13	an	an	DT
cord-312486-rumqopg0	380	14	interaction	interaction	NN
cord-312486-rumqopg0	380	15	between	between	IN
cord-312486-rumqopg0	380	16	an	an	DT
cord-312486-rumqopg0	380	17	infectious	infectious	JJ
cord-312486-rumqopg0	380	18	agent	agent	NN
cord-312486-rumqopg0	380	19	and	and	CC
cord-312486-rumqopg0	380	20	the	the	DT
cord-312486-rumqopg0	380	21	human	human	JJ
cord-312486-rumqopg0	380	22	host	host	NN
cord-312486-rumqopg0	380	23	,	,	,
cord-312486-rumqopg0	380	24	even	even	RB
cord-312486-rumqopg0	380	25	when	when	WRB
cord-312486-rumqopg0	380	26	-full	-full	VBZ
cord-312486-rumqopg0	380	27	recovery	recovery	NN
cord-312486-rumqopg0	380	28	-	-	HYPH
cord-312486-rumqopg0	380	29	ensues	ensue	NNS
cord-312486-rumqopg0	380	30	,	,	,
cord-312486-rumqopg0	380	31	does	do	VBZ
cord-312486-rumqopg0	380	32	not	not	RB
cord-312486-rumqopg0	380	33	mean	mean	VB
cord-312486-rumqopg0	380	34	the	the	DT
cord-312486-rumqopg0	380	35	organism	organism	NN
cord-312486-rumqopg0	380	36	is	be	VBZ
cord-312486-rumqopg0	380	37	restored	restore	VBN
cord-312486-rumqopg0	380	38	to	to	IN
cord-312486-rumqopg0	380	39	its	-PRON-	PRP$
cord-312486-rumqopg0	380	40	previous	previous	JJ
cord-312486-rumqopg0	380	41	state	state	NN
cord-312486-rumqopg0	380	42	(	(	-LRB-
cord-312486-rumqopg0	380	43	before	before	IN
cord-312486-rumqopg0	380	44	the	the	DT
cord-312486-rumqopg0	380	45	encounter	encounter	NN
cord-312486-rumqopg0	380	46	)	)	-RRB-
cord-312486-rumqopg0	380	47	,	,	,
cord-312486-rumqopg0	380	48	but	but	CC
cord-312486-rumqopg0	380	49	rather	rather	RB
cord-312486-rumqopg0	380	50	the	the	DT
cord-312486-rumqopg0	380	51	organism	organism	NN
cord-312486-rumqopg0	380	52	acquires	acquire	VBZ
cord-312486-rumqopg0	380	53	a	a	DT
cord-312486-rumqopg0	380	54	new	new	JJ
cord-312486-rumqopg0	380	55	equilibrium	equilibrium	NN
cord-312486-rumqopg0	380	56	.	.	.
cord-312486-rumqopg0	381	1	As	as	IN
cord-312486-rumqopg0	381	2	the	the	DT
cord-312486-rumqopg0	381	3	French	french	JJ
cord-312486-rumqopg0	381	4	physician	physician	NN
cord-312486-rumqopg0	381	5	and	and	CC
cord-312486-rumqopg0	381	6	philosopher	philosopher	NN
cord-312486-rumqopg0	381	7	George	George	NNP
cord-312486-rumqopg0	381	8	Canguilhem	Canguilhem	NNP
cord-312486-rumqopg0	381	9	wrote	write	VBD
cord-312486-rumqopg0	381	10	some	some	DT
cord-312486-rumqopg0	381	11	75	75	CD
cord-312486-rumqopg0	381	12	years	year	NNS
cord-312486-rumqopg0	381	13	ago	ago	RB
cord-312486-rumqopg0	381	14	:	:	:
cord-312486-rumqopg0	382	1	-contrary	-contrary	JJ
cord-312486-rumqopg0	382	2	to	to	IN
cord-312486-rumqopg0	382	3	orthodox	orthodox	JJ
cord-312486-rumqopg0	382	4	medical	medical	JJ
cord-312486-rumqopg0	382	5	teaching	teaching	NN
cord-312486-rumqopg0	382	6	,	,	,
cord-312486-rumqopg0	382	7	health	health	NN
cord-312486-rumqopg0	382	8	is	be	VBZ
cord-312486-rumqopg0	382	9	not	not	RB
cord-312486-rumqopg0	382	10	some	some	DT
cord-312486-rumqopg0	382	11	absolute	absolute	JJ
cord-312486-rumqopg0	382	12	state	state	NN
cord-312486-rumqopg0	382	13	of	of	IN
cord-312486-rumqopg0	382	14	perfect	perfect	JJ
cord-312486-rumqopg0	382	15	physical	physical	JJ
cord-312486-rumqopg0	382	16	and	and	CC
cord-312486-rumqopg0	382	17	mental	mental	JJ
cord-312486-rumqopg0	382	18	wellbeing	wellbeing	NN
cord-312486-rumqopg0	382	19	.	.	.
cord-312486-rumqopg0	383	1	It	-PRON-	PRP
cord-312486-rumqopg0	383	2	is	be	VBZ
cord-312486-rumqopg0	383	3	the	the	DT
cord-312486-rumqopg0	383	4	margin	margin	NN
cord-312486-rumqopg0	383	5	of	of	IN
cord-312486-rumqopg0	383	6	tolerance	tolerance	NN
cord-312486-rumqopg0	383	7	for	for	IN
cord-312486-rumqopg0	383	8	the	the	DT
cord-312486-rumqopg0	383	9	inconsistencies	inconsistency	NNS
cord-312486-rumqopg0	383	10	of	of	IN
cord-312486-rumqopg0	383	11	the	the	DT
cord-312486-rumqopg0	383	12	environment	environment	NN
cord-312486-rumqopg0	383	13	…	…	NFP
cord-312486-rumqopg0	383	14	Disease	Disease	NNP
cord-312486-rumqopg0	383	15	is	be	VBZ
cord-312486-rumqopg0	383	16	not	not	RB
cord-312486-rumqopg0	383	17	simply	simply	RB
cord-312486-rumqopg0	383	18	disequilibrium	disequilibrium	NN
cord-312486-rumqopg0	383	19	or	or	CC
cord-312486-rumqopg0	383	20	discordance	discordance	NN
cord-312486-rumqopg0	383	21	;	;	:
cord-312486-rumqopg0	383	22	it	-PRON-	PRP
cord-312486-rumqopg0	383	23	is	be	VBZ
cord-312486-rumqopg0	383	24	an	an	DT
cord-312486-rumqopg0	383	25	effort	effort	NN
cord-312486-rumqopg0	383	26	on	on	IN
cord-312486-rumqopg0	383	27	the	the	DT
cord-312486-rumqopg0	383	28	part	part	NN
cord-312486-rumqopg0	383	29	of	of	IN
cord-312486-rumqopg0	383	30	nature	nature	NN
cord-312486-rumqopg0	383	31	to	to	TO
cord-312486-rumqopg0	383	32	effect	effect	VB
cord-312486-rumqopg0	383	33	a	a	DT
cord-312486-rumqopg0	383	34	new	new	JJ
cord-312486-rumqopg0	383	35	equilibrium	equilibrium	NN
cord-312486-rumqopg0	383	36	in	in	IN
cord-312486-rumqopg0	383	37	man‖	man‖	NN
cord-312486-rumqopg0	383	38	[	[	-LRB-
cord-312486-rumqopg0	383	39	165	165	CD
cord-312486-rumqopg0	383	40	]	]	-RRB-
cord-312486-rumqopg0	383	41	.	.	.
cord-312486-rumqopg0	384	1	We	-PRON-	PRP
cord-312486-rumqopg0	384	2	have	have	VBP
cord-312486-rumqopg0	384	3	learned	learn	VBN
cord-312486-rumqopg0	384	4	a	a	DT
cord-312486-rumqopg0	384	5	tremendous	tremendous	JJ
cord-312486-rumqopg0	384	6	amount	amount	NN
cord-312486-rumqopg0	384	7	about	about	IN
cord-312486-rumqopg0	384	8	SARS	SARS	NNP
cord-312486-rumqopg0	384	9	-	-	HYPH
cord-312486-rumqopg0	384	10	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	384	11	and	and	CC
cord-312486-rumqopg0	384	12	COVID-19	covid-19	VB
cord-312486-rumqopg0	384	13	in	in	IN
cord-312486-rumqopg0	384	14	a	a	DT
cord-312486-rumqopg0	384	15	short	short	JJ
cord-312486-rumqopg0	384	16	amount	amount	NN
cord-312486-rumqopg0	384	17	of	of	IN
cord-312486-rumqopg0	384	18	time	time	NN
cord-312486-rumqopg0	384	19	.	.	.
cord-312486-rumqopg0	385	1	The	the	DT
cord-312486-rumqopg0	385	2	efficient	efficient	JJ
cord-312486-rumqopg0	385	3	transmission	transmission	NN
cord-312486-rumqopg0	385	4	of	of	IN
cord-312486-rumqopg0	385	5	data	datum	NNS
cord-312486-rumqopg0	385	6	exhibited	exhibit	VBN
cord-312486-rumqopg0	385	7	during	during	IN
cord-312486-rumqopg0	385	8	this	this	DT
cord-312486-rumqopg0	385	9	time	time	NN
cord-312486-rumqopg0	385	10	,	,	,
cord-312486-rumqopg0	385	11	has	have	VBZ
cord-312486-rumqopg0	385	12	been	be	VBN
cord-312486-rumqopg0	385	13	surpassed	surpass	VBN
cord-312486-rumqopg0	385	14	only	only	RB
cord-312486-rumqopg0	385	15	by	by	IN
cord-312486-rumqopg0	385	16	the	the	DT
cord-312486-rumqopg0	385	17	efficient	efficient	JJ
cord-312486-rumqopg0	385	18	transmission	transmission	NN
cord-312486-rumqopg0	385	19	of	of	IN
cord-312486-rumqopg0	385	20	the	the	DT
cord-312486-rumqopg0	385	21	virus	virus	NN
cord-312486-rumqopg0	385	22	itself	-PRON-	PRP
cord-312486-rumqopg0	385	23	.	.	.
cord-312486-rumqopg0	386	1	Although	although	IN
cord-312486-rumqopg0	386	2	originally	originally	RB
cord-312486-rumqopg0	386	3	conceptualized	conceptualize	VBN
cord-312486-rumqopg0	386	4	as	as	IN
cord-312486-rumqopg0	386	5	a	a	DT
cord-312486-rumqopg0	386	6	primarily	primarily	RB
cord-312486-rumqopg0	386	7	respiratory	respiratory	JJ
cord-312486-rumqopg0	386	8	viral	viral	JJ
cord-312486-rumqopg0	386	9	disease	disease	NN
cord-312486-rumqopg0	386	10	,	,	,
cord-312486-rumqopg0	386	11	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	386	12	is	be	VBZ
cord-312486-rumqopg0	386	13	now	now	RB
cord-312486-rumqopg0	386	14	clearly	clearly	RB
cord-312486-rumqopg0	386	15	recognized	recognize	VBN
cord-312486-rumqopg0	386	16	as	as	IN
cord-312486-rumqopg0	386	17	a	a	DT
cord-312486-rumqopg0	386	18	far	far	RB
cord-312486-rumqopg0	386	19	more	more	RBR
cord-312486-rumqopg0	386	20	complex	complex	JJ
cord-312486-rumqopg0	386	21	,	,	,
cord-312486-rumqopg0	386	22	multi	multi	JJ
cord-312486-rumqopg0	386	23	-	-	JJ
cord-312486-rumqopg0	386	24	organ	organ	NN
cord-312486-rumqopg0	386	25	,	,	,
cord-312486-rumqopg0	386	26	and	and	CC
cord-312486-rumqopg0	386	27	heterogeneous	heterogeneous	JJ
cord-312486-rumqopg0	386	28	illness	illness	NN
cord-312486-rumqopg0	386	29	.	.	.
cord-312486-rumqopg0	387	1	As	as	IN
cord-312486-rumqopg0	387	2	with	with	IN
cord-312486-rumqopg0	387	3	SARS	SARS	NNP
cord-312486-rumqopg0	387	4	-	-	HYPH
cord-312486-rumqopg0	387	5	CoV-1	CoV-1	NNP
cord-312486-rumqopg0	387	6	and	and	CC
cord-312486-rumqopg0	387	7	MERS	MERS	NNP
cord-312486-rumqopg0	387	8	-	-	HYPH
cord-312486-rumqopg0	387	9	CoV	CoV	NNP
cord-312486-rumqopg0	387	10	,	,	,
cord-312486-rumqopg0	387	11	the	the	DT
cord-312486-rumqopg0	387	12	important	important	JJ
cord-312486-rumqopg0	387	13	considerations	consideration	NNS
cord-312486-rumqopg0	387	14	for	for	IN
cord-312486-rumqopg0	387	15	the	the	DT
cord-312486-rumqopg0	387	16	delicate	delicate	JJ
cord-312486-rumqopg0	387	17	balance	balance	NN
cord-312486-rumqopg0	387	18	of	of	IN
cord-312486-rumqopg0	387	19	the	the	DT
cord-312486-rumqopg0	387	20	viral	viral	JJ
cord-312486-rumqopg0	387	21	-	-	HYPH
cord-312486-rumqopg0	387	22	host	host	NN
cord-312486-rumqopg0	387	23	interaction	interaction	NN
cord-312486-rumqopg0	387	24	that	that	WDT
cord-312486-rumqopg0	387	25	are	be	VBP
cord-312486-rumqopg0	387	26	responsible	responsible	JJ
cord-312486-rumqopg0	387	27	for	for	IN
cord-312486-rumqopg0	387	28	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	387	29	are	be	VBP
cord-312486-rumqopg0	387	30	now	now	RB
cord-312486-rumqopg0	387	31	increasingly	increasingly	RB
cord-312486-rumqopg0	387	32	appreciated	appreciate	VBN
cord-312486-rumqopg0	387	33	:	:	:
cord-312486-rumqopg0	387	34	(	(	-LRB-
cord-312486-rumqopg0	387	35	1	1	LS
cord-312486-rumqopg0	387	36	)	)	-RRB-
cord-312486-rumqopg0	387	37	fast	fast	JJ
cord-312486-rumqopg0	387	38	and	and	CC
cord-312486-rumqopg0	387	39	robust	robust	JJ
cord-312486-rumqopg0	387	40	initial	initial	JJ
cord-312486-rumqopg0	387	41	viral	viral	JJ
cord-312486-rumqopg0	387	42	replication	replication	NN
cord-312486-rumqopg0	387	43	;	;	:
cord-312486-rumqopg0	387	44	(	(	-LRB-
cord-312486-rumqopg0	387	45	2	2	LS
cord-312486-rumqopg0	387	46	)	)	-RRB-
cord-312486-rumqopg0	387	47	early	early	JJ
cord-312486-rumqopg0	387	48	viral	viral	JJ
cord-312486-rumqopg0	387	49	inhibition	inhibition	NN
cord-312486-rumqopg0	387	50	of	of	IN
cord-312486-rumqopg0	387	51	IFN	IFN	NNP
cord-312486-rumqopg0	387	52	induction	induction	NN
cord-312486-rumqopg0	387	53	and	and	CC
cord-312486-rumqopg0	387	54	signaling	signaling	NN
cord-312486-rumqopg0	387	55	causing	cause	VBG
cord-312486-rumqopg0	387	56	a	a	DT
cord-312486-rumqopg0	387	57	delayed	delay	VBN
cord-312486-rumqopg0	387	58	IFN	IFN	NNP
cord-312486-rumqopg0	387	59	expression	expression	NN
cord-312486-rumqopg0	387	60	which	which	WDT
cord-312486-rumqopg0	387	61	drives	drive	VBZ
cord-312486-rumqopg0	387	62	immunopathology	immunopathology	NN
cord-312486-rumqopg0	387	63	;	;	,
cord-312486-rumqopg0	387	64	(	(	-LRB-
cord-312486-rumqopg0	387	65	3	3	LS
cord-312486-rumqopg0	387	66	)	)	-RRB-
cord-312486-rumqopg0	387	67	out	out	IN
cord-312486-rumqopg0	387	68	of	of	IN
cord-312486-rumqopg0	387	69	balance	balance	NN
cord-312486-rumqopg0	387	70	antiviral	antiviral	JJ
cord-312486-rumqopg0	387	71	innate	innate	JJ
cord-312486-rumqopg0	387	72	immune	immune	JJ
cord-312486-rumqopg0	387	73	response	response	NN
cord-312486-rumqopg0	387	74	becomes	become	VBZ
cord-312486-rumqopg0	387	75	immunopathogenic	immunopathogenic	JJ
cord-312486-rumqopg0	387	76	;	;	,
cord-312486-rumqopg0	387	77	and	and	CC
cord-312486-rumqopg0	387	78	lastly	lastly	RB
cord-312486-rumqopg0	387	79	(	(	-LRB-
cord-312486-rumqopg0	387	80	4	4	LS
cord-312486-rumqopg0	387	81	)	)	-RRB-
cord-312486-rumqopg0	387	82	disintegration	disintegration	NN
cord-312486-rumqopg0	387	83	of	of	IN
cord-312486-rumqopg0	387	84	the	the	DT
cord-312486-rumqopg0	387	85	adaptive	adaptive	JJ
cord-312486-rumqopg0	387	86	immune	immune	JJ
cord-312486-rumqopg0	387	87	response	response	NN
cord-312486-rumqopg0	387	88	.	.	.
cord-312486-rumqopg0	388	1	Paul	Paul	NNP
cord-312486-rumqopg0	388	2	Ehrlich	Ehrlich	NNP
cord-312486-rumqopg0	388	3	's	's	POS
cord-312486-rumqopg0	388	4	prediction	prediction	NN
cord-312486-rumqopg0	388	5	of	of	IN
cord-312486-rumqopg0	388	6	horror	horror	NN
cord-312486-rumqopg0	388	7	autotoxicus	autotoxicus	NNP
cord-312486-rumqopg0	388	8	-	-	:
cord-312486-rumqopg0	388	9	at	at	IN
cord-312486-rumqopg0	388	10	the	the	DT
cord-312486-rumqopg0	388	11	turn	turn	NN
cord-312486-rumqopg0	388	12	of	of	IN
cord-312486-rumqopg0	388	13	the	the	DT
cord-312486-rumqopg0	388	14	20	20	CD
cord-312486-rumqopg0	388	15	th	th	XX
cord-312486-rumqopg0	388	16	century	century	NN
cord-312486-rumqopg0	388	17	-	-	,
cord-312486-rumqopg0	388	18	has	have	VBZ
cord-312486-rumqopg0	388	19	been	be	VBN
cord-312486-rumqopg0	388	20	realized	realize	VBN
cord-312486-rumqopg0	388	21	by	by	IN
cord-312486-rumqopg0	388	22	the	the	DT
cord-312486-rumqopg0	388	23	innate	innate	JJ
cord-312486-rumqopg0	388	24	immune	immune	JJ
cord-312486-rumqopg0	388	25	response	response	NN
cord-312486-rumqopg0	388	26	to	to	IN
cord-312486-rumqopg0	388	27	CoV	CoV	NNP
cord-312486-rumqopg0	388	28	in	in	IN
cord-312486-rumqopg0	388	29	the	the	DT
cord-312486-rumqopg0	388	30	21	21	CD
cord-312486-rumqopg0	388	31	st	st	NNP
cord-312486-rumqopg0	388	32	century	century	NN
cord-312486-rumqopg0	388	33	.	.	.
cord-312486-rumqopg0	389	1	The	the	DT
cord-312486-rumqopg0	389	2	language	language	NN
cord-312486-rumqopg0	389	3	of	of	IN
cord-312486-rumqopg0	389	4	immunology	immunology	NN
cord-312486-rumqopg0	389	5	is	be	VBZ
cord-312486-rumqopg0	389	6	rife	rife	JJ
cord-312486-rumqopg0	389	7	with	with	IN
cord-312486-rumqopg0	389	8	war	war	NN
cord-312486-rumqopg0	389	9	metaphors	metaphor	NNS
cord-312486-rumqopg0	389	10	.	.	.
cord-312486-rumqopg0	390	1	For	for	IN
cord-312486-rumqopg0	390	2	over	over	IN
cord-312486-rumqopg0	390	3	a	a	DT
cord-312486-rumqopg0	390	4	hundred	hundred	CD
cord-312486-rumqopg0	390	5	years	year	NNS
cord-312486-rumqopg0	390	6	we	-PRON-	PRP
cord-312486-rumqopg0	390	7	have	have	VBP
cord-312486-rumqopg0	390	8	been	be	VBN
cord-312486-rumqopg0	390	9	educated	educate	VBN
cord-312486-rumqopg0	390	10	to	to	TO
cord-312486-rumqopg0	390	11	believe	believe	VB
cord-312486-rumqopg0	390	12	in	in	IN
cord-312486-rumqopg0	390	13	the	the	DT
cord-312486-rumqopg0	390	14	metaphor	metaphor	NN
cord-312486-rumqopg0	390	15	that	that	WDT
cord-312486-rumqopg0	390	16	the	the	DT
cord-312486-rumqopg0	390	17	immune	immune	JJ
cord-312486-rumqopg0	390	18	system	system	NN
cord-312486-rumqopg0	390	19	acts	act	VBZ
cord-312486-rumqopg0	390	20	as	as	IN
cord-312486-rumqopg0	390	21	an	an	DT
cord-312486-rumqopg0	390	22	army	army	NN
cord-312486-rumqopg0	390	23	defending	defend	VBG
cord-312486-rumqopg0	390	24	our	-PRON-	PRP$
cord-312486-rumqopg0	390	25	bodies	body	NNS
cord-312486-rumqopg0	390	26	.	.	.
cord-312486-rumqopg0	391	1	As	as	IN
cord-312486-rumqopg0	391	2	Richard	Richard	NNP
cord-312486-rumqopg0	391	3	Lewontin	Lewontin	NNP
cord-312486-rumqopg0	391	4	has	have	VBZ
cord-312486-rumqopg0	391	5	written	write	VBN
cord-312486-rumqopg0	391	6	:	:	:
cord-312486-rumqopg0	391	7	-While	-while	UH
cord-312486-rumqopg0	391	8	we	-PRON-	PRP
cord-312486-rumqopg0	391	9	can	can	MD
cord-312486-rumqopg0	391	10	not	not	RB
cord-312486-rumqopg0	391	11	dispense	dispense	VB
cord-312486-rumqopg0	391	12	with	with	IN
cord-312486-rumqopg0	391	13	metaphors	metaphor	NNS
cord-312486-rumqopg0	391	14	in	in	IN
cord-312486-rumqopg0	391	15	thinking	think	VBG
cord-312486-rumqopg0	391	16	about	about	IN
cord-312486-rumqopg0	391	17	nature	nature	NN
cord-312486-rumqopg0	391	18	,	,	,
cord-312486-rumqopg0	391	19	there	there	EX
cord-312486-rumqopg0	391	20	is	be	VBZ
cord-312486-rumqopg0	391	21	a	a	DT
cord-312486-rumqopg0	391	22	great	great	JJ
cord-312486-rumqopg0	391	23	risk	risk	NN
cord-312486-rumqopg0	391	24	of	of	IN
cord-312486-rumqopg0	391	25	confusing	confuse	VBG
cord-312486-rumqopg0	391	26	the	the	DT
cord-312486-rumqopg0	391	27	metaphor	metaphor	NN
cord-312486-rumqopg0	391	28	with	with	IN
cord-312486-rumqopg0	391	29	the	the	DT
cord-312486-rumqopg0	391	30	thing	thing	NN
cord-312486-rumqopg0	391	31	of	of	IN
cord-312486-rumqopg0	391	32	real	real	JJ
cord-312486-rumqopg0	391	33	interest	interest	NN
cord-312486-rumqopg0	391	34	.	.	.
cord-312486-rumqopg0	392	1	We	-PRON-	PRP
cord-312486-rumqopg0	392	2	cease	cease	VBP
cord-312486-rumqopg0	392	3	to	to	TO
cord-312486-rumqopg0	392	4	see	see	VB
cord-312486-rumqopg0	392	5	the	the	DT
cord-312486-rumqopg0	392	6	world	world	NN
cord-312486-rumqopg0	392	7	as	as	IN
cord-312486-rumqopg0	392	8	if	if	IN
cord-312486-rumqopg0	392	9	it	-PRON-	PRP
cord-312486-rumqopg0	392	10	were	be	VBD
cord-312486-rumqopg0	392	11	like	like	IN
cord-312486-rumqopg0	392	12	a	a	DT
cord-312486-rumqopg0	392	13	machine	machine	NN
cord-312486-rumqopg0	392	14	and	and	CC
cord-312486-rumqopg0	392	15	take	take	VB
cord-312486-rumqopg0	392	16	it	-PRON-	PRP
cord-312486-rumqopg0	392	17	to	to	TO
cord-312486-rumqopg0	392	18	be	be	VB
cord-312486-rumqopg0	392	19	a	a	DT
cord-312486-rumqopg0	392	20	machine	machine	NN
cord-312486-rumqopg0	392	21	.	.	.
cord-312486-rumqopg0	393	1	The	the	DT
cord-312486-rumqopg0	393	2	result	result	NN
cord-312486-rumqopg0	393	3	is	be	VBZ
cord-312486-rumqopg0	393	4	that	that	IN
cord-312486-rumqopg0	393	5	the	the	DT
cord-312486-rumqopg0	393	6	properties	property	NNS
cord-312486-rumqopg0	393	7	we	-PRON-	PRP
cord-312486-rumqopg0	393	8	ascribe	ascribe	VBP
cord-312486-rumqopg0	393	9	to	to	IN
cord-312486-rumqopg0	393	10	our	-PRON-	PRP$
cord-312486-rumqopg0	393	11	object	object	NN
cord-312486-rumqopg0	393	12	of	of	IN
cord-312486-rumqopg0	393	13	interest	interest	NN
cord-312486-rumqopg0	393	14	and	and	CC
cord-312486-rumqopg0	393	15	the	the	DT
cord-312486-rumqopg0	393	16	questions	question	NNS
cord-312486-rumqopg0	393	17	we	-PRON-	PRP
cord-312486-rumqopg0	393	18	ask	ask	VBP
cord-312486-rumqopg0	393	19	about	about	IN
cord-312486-rumqopg0	393	20	it	-PRON-	PRP
cord-312486-rumqopg0	393	21	J	J	NNP
cord-312486-rumqopg0	393	22	o	o	NNP
cord-312486-rumqopg0	394	1	u	u	NNP
cord-312486-rumqopg0	394	2	r	r	NNP
cord-312486-rumqopg0	394	3	n	n	NN
cord-312486-rumqopg0	394	4	a	a	DT
cord-312486-rumqopg0	394	5	l	l	NN
cord-312486-rumqopg0	394	6	P	p	NN
cord-312486-rumqopg0	394	7	r	r	NN
cord-312486-rumqopg0	394	8	e	e	NN
cord-312486-rumqopg0	394	9	-p	-p	NN
cord-312486-rumqopg0	395	1	r	r	NN
cord-312486-rumqopg0	395	2	o	o	NN
cord-312486-rumqopg0	395	3	o	o	NN
cord-312486-rumqopg0	395	4	f	f	NN
cord-312486-rumqopg0	395	5	reinforce	reinforce	VB
cord-312486-rumqopg0	395	6	the	the	DT
cord-312486-rumqopg0	395	7	original	original	JJ
cord-312486-rumqopg0	395	8	metaphorical	metaphorical	JJ
cord-312486-rumqopg0	395	9	image	image	NN
cord-312486-rumqopg0	395	10	and	and	CC
cord-312486-rumqopg0	395	11	we	-PRON-	PRP
cord-312486-rumqopg0	395	12	miss	miss	VBP
cord-312486-rumqopg0	395	13	the	the	DT
cord-312486-rumqopg0	395	14	aspects	aspect	NNS
cord-312486-rumqopg0	395	15	of	of	IN
cord-312486-rumqopg0	395	16	the	the	DT
cord-312486-rumqopg0	395	17	system	system	NN
cord-312486-rumqopg0	395	18	that	that	WDT
cord-312486-rumqopg0	395	19	do	do	VBP
cord-312486-rumqopg0	395	20	not	not	RB
cord-312486-rumqopg0	395	21	fit	fit	VB
cord-312486-rumqopg0	395	22	the	the	DT
cord-312486-rumqopg0	395	23	metaphorical	metaphorical	JJ
cord-312486-rumqopg0	395	24	approximation‖	approximation‖	NN
cord-312486-rumqopg0	395	25	[	[	-LRB-
cord-312486-rumqopg0	395	26	166	166	CD
cord-312486-rumqopg0	395	27	]	]	-RRB-
cord-312486-rumqopg0	395	28	.	.	.
cord-312486-rumqopg0	396	1	What	what	WP
cord-312486-rumqopg0	396	2	has	have	VBZ
cord-312486-rumqopg0	396	3	SARS	SARS	NNP
cord-312486-rumqopg0	396	4	-	-	HYPH
cord-312486-rumqopg0	396	5	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	396	6	revealed	reveal	VBD
cord-312486-rumqopg0	396	7	?	?	.
cord-312486-rumqopg0	397	1	For	for	IN
cord-312486-rumqopg0	397	2	me	-PRON-	PRP
cord-312486-rumqopg0	397	3	,	,	,
cord-312486-rumqopg0	397	4	the	the	DT
cord-312486-rumqopg0	397	5	answer	answer	NN
cord-312486-rumqopg0	397	6	is	be	VBZ
cord-312486-rumqopg0	397	7	our	-PRON-	PRP$
cord-312486-rumqopg0	397	8	immune	immune	JJ
cord-312486-rumqopg0	397	9	response	response	NN
cord-312486-rumqopg0	397	10	to	to	IN
cord-312486-rumqopg0	397	11	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	397	12	serves	serve	NNS
cord-312486-rumqopg0	397	13	as	as	IN
cord-312486-rumqopg0	397	14	proof	proof	NN
cord-312486-rumqopg0	397	15	of	of	IN
cord-312486-rumqopg0	397	16	everything	everything	NN
cord-312486-rumqopg0	397	17	I	-PRON-	PRP
cord-312486-rumqopg0	397	18	have	have	VBP
cord-312486-rumqopg0	397	19	long	long	RB
cord-312486-rumqopg0	397	20	thought	thought	NN
cord-312486-rumqopg0	397	21	was	be	VBD
cord-312486-rumqopg0	397	22	wrong	wrong	JJ
cord-312486-rumqopg0	397	23	with	with	IN
cord-312486-rumqopg0	397	24	viewing	view	VBG
cord-312486-rumqopg0	397	25	the	the	DT
cord-312486-rumqopg0	397	26	(	(	-LRB-
cord-312486-rumqopg0	397	27	adaptive	adaptive	JJ
cord-312486-rumqopg0	397	28	)	)	-RRB-
cord-312486-rumqopg0	397	29	immune	immune	JJ
cord-312486-rumqopg0	397	30	system	system	NN
cord-312486-rumqopg0	397	31	as	as	IN
cord-312486-rumqopg0	397	32	a	a	DT
cord-312486-rumqopg0	397	33	defense	defense	NN
cord-312486-rumqopg0	397	34	organization	organization	NN
cord-312486-rumqopg0	397	35	:	:	:
cord-312486-rumqopg0	398	1	It	-PRON-	PRP
cord-312486-rumqopg0	398	2	reacts	react	VBZ
cord-312486-rumqopg0	398	3	too	too	RB
cord-312486-rumqopg0	398	4	slowly	slowly	RB
cord-312486-rumqopg0	398	5	.	.	.
cord-312486-rumqopg0	399	1	It	-PRON-	PRP
cord-312486-rumqopg0	399	2	fights	fight	VBZ
cord-312486-rumqopg0	399	3	today	today	NN
cord-312486-rumqopg0	399	4	's	's	POS
cord-312486-rumqopg0	399	5	threats	threat	NNS
cord-312486-rumqopg0	399	6	with	with	IN
cord-312486-rumqopg0	399	7	the	the	DT
cord-312486-rumqopg0	399	8	solutions	solution	NNS
cord-312486-rumqopg0	399	9	of	of	IN
cord-312486-rumqopg0	399	10	past	past	JJ
cord-312486-rumqopg0	399	11	problems	problem	NNS
cord-312486-rumqopg0	399	12	.	.	.
cord-312486-rumqopg0	400	1	It	-PRON-	PRP
cord-312486-rumqopg0	400	2	is	be	VBZ
cord-312486-rumqopg0	400	3	susceptible	susceptible	JJ
cord-312486-rumqopg0	400	4	to	to	IN
cord-312486-rumqopg0	400	5	exploitation	exploitation	NN
cord-312486-rumqopg0	400	6	.	.	.
cord-312486-rumqopg0	401	1	It	-PRON-	PRP
cord-312486-rumqopg0	401	2	destroys	destroy	VBZ
cord-312486-rumqopg0	401	3	that	that	IN
cord-312486-rumqopg0	401	4	which	which	WDT
cord-312486-rumqopg0	401	5	it	-PRON-	PRP
cord-312486-rumqopg0	401	6	intended	intend	VBD
cord-312486-rumqopg0	401	7	to	to	TO
cord-312486-rumqopg0	401	8	protect	protect	VB
cord-312486-rumqopg0	401	9	.	.	.
cord-312486-rumqopg0	402	1	It	-PRON-	PRP
cord-312486-rumqopg0	402	2	is	be	VBZ
cord-312486-rumqopg0	402	3	large	large	JJ
cord-312486-rumqopg0	402	4	,	,	,
cord-312486-rumqopg0	402	5	complicated	complicated	JJ
cord-312486-rumqopg0	402	6	,	,	,
cord-312486-rumqopg0	402	7	elaborate	elaborate	JJ
cord-312486-rumqopg0	402	8	and	and	CC
cord-312486-rumqopg0	402	9	wasteful	wasteful	JJ
cord-312486-rumqopg0	402	10	[	[	-LRB-
cord-312486-rumqopg0	402	11	167	167	CD
cord-312486-rumqopg0	402	12	]	]	-RRB-
cord-312486-rumqopg0	402	13	.	.	.
cord-312486-rumqopg0	403	1	If	if	IN
cord-312486-rumqopg0	403	2	you	-PRON-	PRP
cord-312486-rumqopg0	403	3	stand	stand	VBP
cord-312486-rumqopg0	403	4	back	back	RB
cord-312486-rumqopg0	403	5	and	and	CC
cord-312486-rumqopg0	403	6	evaluate	evaluate	VB
cord-312486-rumqopg0	403	7	how	how	WRB
cord-312486-rumqopg0	403	8	ineffective	ineffective	JJ
cord-312486-rumqopg0	403	9	is	be	VBZ
cord-312486-rumqopg0	403	10	the	the	DT
cord-312486-rumqopg0	403	11	immune	immune	JJ
cord-312486-rumqopg0	403	12	system	system	NN
cord-312486-rumqopg0	403	13	as	as	IN
cord-312486-rumqopg0	403	14	a	a	DT
cord-312486-rumqopg0	403	15	defense	defense	NN
cord-312486-rumqopg0	403	16	organization	organization	NN
cord-312486-rumqopg0	403	17	,	,	,
cord-312486-rumqopg0	403	18	it	-PRON-	PRP
cord-312486-rumqopg0	403	19	is	be	VBZ
cord-312486-rumqopg0	403	20	only	only	RB
cord-312486-rumqopg0	403	21	logical	logical	JJ
cord-312486-rumqopg0	403	22	to	to	TO
cord-312486-rumqopg0	403	23	conclude	conclude	VB
cord-312486-rumqopg0	403	24	that	that	IN
cord-312486-rumqopg0	403	25	it	-PRON-	PRP
cord-312486-rumqopg0	403	26	was	be	VBD
cord-312486-rumqopg0	403	27	never	never	RB
cord-312486-rumqopg0	403	28	intended	intend	VBN
cord-312486-rumqopg0	403	29	as	as	IN
cord-312486-rumqopg0	403	30	one	one	CD
cord-312486-rumqopg0	403	31	.	.	.
cord-312486-rumqopg0	404	1	SARS	SARS	NNP
cord-312486-rumqopg0	404	2	-	-	HYPH
cord-312486-rumqopg0	404	3	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	404	4	will	will	MD
cord-312486-rumqopg0	404	5	eventually	eventually	RB
cord-312486-rumqopg0	404	6	be	be	VB
cord-312486-rumqopg0	404	7	contained	contain	VBN
cord-312486-rumqopg0	404	8	,	,	,
cord-312486-rumqopg0	404	9	but	but	CC
cord-312486-rumqopg0	404	10	not	not	RB
cord-312486-rumqopg0	404	11	by	by	IN
cord-312486-rumqopg0	404	12	our	-PRON-	PRP$
cord-312486-rumqopg0	404	13	immune	immune	JJ
cord-312486-rumqopg0	404	14	systems	system	NNS
cord-312486-rumqopg0	404	15	.	.	.
cord-312486-rumqopg0	405	1	Rather	rather	RB
cord-312486-rumqopg0	405	2	,	,	,
cord-312486-rumqopg0	405	3	by	by	IN
cord-312486-rumqopg0	405	4	the	the	DT
cord-312486-rumqopg0	405	5	international	international	NNP
cord-312486-rumqopg0	405	6	brotherhood	brotherhood	NNP
cord-312486-rumqopg0	405	7	of	of	IN
cord-312486-rumqopg0	405	8	the	the	DT
cord-312486-rumqopg0	405	9	scientific	scientific	JJ
cord-312486-rumqopg0	405	10	community	community	NN
cord-312486-rumqopg0	405	11	.	.	.
cord-312486-rumqopg0	406	1	Epidemics	epidemic	NNS
cord-312486-rumqopg0	406	2	have	have	VBP
cord-312486-rumqopg0	406	3	always	always	RB
cord-312486-rumqopg0	406	4	played	play	VBN
cord-312486-rumqopg0	406	5	a	a	DT
cord-312486-rumqopg0	406	6	natural	natural	JJ
cord-312486-rumqopg0	406	7	part	part	NN
cord-312486-rumqopg0	406	8	in	in	IN
cord-312486-rumqopg0	406	9	the	the	DT
cord-312486-rumqopg0	406	10	fabric	fabric	NN
cord-312486-rumqopg0	406	11	of	of	IN
cord-312486-rumqopg0	406	12	human	human	JJ
cord-312486-rumqopg0	406	13	history	history	NN
cord-312486-rumqopg0	406	14	,	,	,
cord-312486-rumqopg0	406	15	but	but	CC
cord-312486-rumqopg0	406	16	there	there	EX
cord-312486-rumqopg0	406	17	has	have	VBZ
cord-312486-rumqopg0	406	18	never	never	RB
cord-312486-rumqopg0	406	19	been	be	VBN
cord-312486-rumqopg0	406	20	a	a	DT
cord-312486-rumqopg0	406	21	time	time	NN
cord-312486-rumqopg0	406	22	in	in	IN
cord-312486-rumqopg0	406	23	history	history	NN
cord-312486-rumqopg0	406	24	where	where	WRB
cord-312486-rumqopg0	406	25	so	so	RB
cord-312486-rumqopg0	406	26	many	many	JJ
cord-312486-rumqopg0	406	27	different	different	JJ
cord-312486-rumqopg0	406	28	and	and	CC
cord-312486-rumqopg0	406	29	powerful	powerful	JJ
cord-312486-rumqopg0	406	30	tools	tool	NNS
cord-312486-rumqopg0	406	31	were	be	VBD
cord-312486-rumqopg0	406	32	available	available	JJ
cord-312486-rumqopg0	406	33	to	to	TO
cord-312486-rumqopg0	406	34	accomplish	accomplish	VB
cord-312486-rumqopg0	406	35	this	this	DT
cord-312486-rumqopg0	406	36	task	task	NN
cord-312486-rumqopg0	406	37	.	.	.
cord-312486-rumqopg0	407	1	Of	of	IN
cord-312486-rumqopg0	407	2	all	all	DT
cord-312486-rumqopg0	407	3	human	human	JJ
cord-312486-rumqopg0	407	4	conditions	condition	NNS
cord-312486-rumqopg0	407	5	that	that	WDT
cord-312486-rumqopg0	407	6	disseminate	disseminate	VBP
cord-312486-rumqopg0	407	7	virulent	virulent	JJ
cord-312486-rumqopg0	407	8	diseases	disease	NNS
cord-312486-rumqopg0	407	9	,	,	,
cord-312486-rumqopg0	407	10	hubris	hubris	NN
cord-312486-rumqopg0	407	11	emerges	emerge	VBZ
cord-312486-rumqopg0	407	12	across	across	IN
cord-312486-rumqopg0	407	13	centuries	century	NNS
cord-312486-rumqopg0	407	14	as	as	IN
cord-312486-rumqopg0	407	15	a	a	DT
cord-312486-rumqopg0	407	16	key	key	JJ
cord-312486-rumqopg0	407	17	driving	drive	VBG
cord-312486-rumqopg0	407	18	force	force	NN
cord-312486-rumqopg0	407	19	.	.	.
cord-312486-rumqopg0	408	1	We	-PRON-	PRP
cord-312486-rumqopg0	408	2	should	should	MD
cord-312486-rumqopg0	408	3	embrace	embrace	VB
cord-312486-rumqopg0	408	4	Cesar	Cesar	NNP
cord-312486-rumqopg0	408	5	Augustus	Augustus	NNP
cord-312486-rumqopg0	408	6	motto	motto	NN
cord-312486-rumqopg0	408	7	-Festina	-Festina	.
cord-312486-rumqopg0	408	8	lente‖	lente‖	NNP
cord-312486-rumqopg0	408	9	,	,	,
cord-312486-rumqopg0	408	10	make	make	VB
cord-312486-rumqopg0	408	11	haste	haste	NN
cord-312486-rumqopg0	408	12	,	,	,
cord-312486-rumqopg0	408	13	slowly	slowly	RB
cord-312486-rumqopg0	408	14	-	-	:
cord-312486-rumqopg0	408	15	even	even	RB
cord-312486-rumqopg0	408	16	or	or	CC
cord-312486-rumqopg0	408	17	especially	especially	RB
cord-312486-rumqopg0	408	18	when	when	WRB
cord-312486-rumqopg0	408	19	you	-PRON-	PRP
cord-312486-rumqopg0	408	20	are	be	VBP
cord-312486-rumqopg0	408	21	feeling	feel	VBG
cord-312486-rumqopg0	408	22	the	the	DT
cord-312486-rumqopg0	408	23	crunch	crunch	NN
cord-312486-rumqopg0	408	24	,	,	,
cord-312486-rumqopg0	408	25	take	take	VB
cord-312486-rumqopg0	408	26	your	-PRON-	PRP$
cord-312486-rumqopg0	408	27	time	time	NN
cord-312486-rumqopg0	408	28	.	.	.
cord-312486-rumqopg0	409	1	This	this	DT
cord-312486-rumqopg0	409	2	is	be	VBZ
cord-312486-rumqopg0	409	3	not	not	RB
cord-312486-rumqopg0	409	4	the	the	DT
cord-312486-rumqopg0	409	5	time	time	NN
cord-312486-rumqopg0	409	6	for	for	IN
cord-312486-rumqopg0	409	7	us	-PRON-	PRP
cord-312486-rumqopg0	409	8	to	to	TO
cord-312486-rumqopg0	409	9	skip	skip	VB
cord-312486-rumqopg0	409	10	corners	corner	NNS
cord-312486-rumqopg0	409	11	.	.	.
cord-312486-rumqopg0	410	1	Table	table	NN
cord-312486-rumqopg0	410	2	1	1	CD
cord-312486-rumqopg0	410	3	.	.	.
cord-312486-rumqopg0	411	1	Comparison	comparison	NN
cord-312486-rumqopg0	411	2	of	of	IN
cord-312486-rumqopg0	411	3	transmissibility	transmissibility	NN
cord-312486-rumqopg0	411	4	expressed	express	VBN
cord-312486-rumqopg0	411	5	as	as	IN
cord-312486-rumqopg0	411	6	reproduction	reproduction	NN
cord-312486-rumqopg0	411	7	number	number	NN
cord-312486-rumqopg0	411	8	,	,	,
cord-312486-rumqopg0	411	9	R	r	NN
cord-312486-rumqopg0	411	10	0	0	CD
cord-312486-rumqopg0	411	11	and	and	CC
cord-312486-rumqopg0	411	12	case	case	NN
cord-312486-rumqopg0	411	13	fatality	fatality	NN
cord-312486-rumqopg0	411	14	rates	rate	NNS
cord-312486-rumqopg0	411	15	of	of	IN
cord-312486-rumqopg0	411	16	selected	select	VBN
cord-312486-rumqopg0	411	17	human	human	JJ
cord-312486-rumqopg0	411	18	viral	viral	JJ
cord-312486-rumqopg0	411	19	diseases	disease	NNS
cord-312486-rumqopg0	411	20	.	.	.
cord-312486-rumqopg0	412	1	Adopted	adopt	VBN
cord-312486-rumqopg0	412	2	with	with	IN
cord-312486-rumqopg0	412	3	changes	change	NNS
cord-312486-rumqopg0	412	4	from	from	IN
cord-312486-rumqopg0	412	5	Wang	Wang	NNP
cord-312486-rumqopg0	412	6	et	et	NNP
cord-312486-rumqopg0	412	7	al	al	NNP
cord-312486-rumqopg0	412	8	.	.	NNP
cord-312486-rumqopg0	412	9	,	,	,
cord-312486-rumqopg0	412	10	[	[	-LRB-
cord-312486-rumqopg0	412	11	26	26	CD
cord-312486-rumqopg0	412	12	]	]	-RRB-
cord-312486-rumqopg0	412	13	.	.	.
cord-312486-rumqopg0	413	1	The	the	DT
cord-312486-rumqopg0	413	2	Disintegration	disintegration	NN
cord-312486-rumqopg0	413	3	of	of	IN
cord-312486-rumqopg0	413	4	the	the	DT
cord-312486-rumqopg0	413	5	Persistence	Persistence	NNP
cord-312486-rumqopg0	413	6	of	of	IN
cord-312486-rumqopg0	413	7	Memory	Memory	NNP
cord-312486-rumqopg0	413	8	(	(	-LRB-
cord-312486-rumqopg0	413	9	1954	1954	CD
cord-312486-rumqopg0	413	10	)	)	-RRB-
cord-312486-rumqopg0	413	11	(	(	-LRB-
cord-312486-rumqopg0	413	12	RT	RT	NNP
cord-312486-rumqopg0	413	13	)	)	-RRB-
cord-312486-rumqopg0	413	14	by	by	IN
cord-312486-rumqopg0	413	15	Salvador	Salvador	NNP
cord-312486-rumqopg0	413	16	Dali	Dali	NNP
cord-312486-rumqopg0	413	17	is	be	VBZ
cord-312486-rumqopg0	413	18	an	an	DT
cord-312486-rumqopg0	413	19	oil	oil	NN
cord-312486-rumqopg0	413	20	on	on	IN
cord-312486-rumqopg0	413	21	canvas	canvas	NN
cord-312486-rumqopg0	413	22	reaction	reaction	NN
cord-312486-rumqopg0	413	23	to	to	IN
cord-312486-rumqopg0	413	24	his	-PRON-	PRP$
cord-312486-rumqopg0	413	25	original	original	JJ
cord-312486-rumqopg0	413	26	work	work	NN
cord-312486-rumqopg0	414	1	The	the	DT
cord-312486-rumqopg0	414	2	Persistence	Persistence	NNP
cord-312486-rumqopg0	414	3	of	of	IN
cord-312486-rumqopg0	414	4	Memory	memory	NN
cord-312486-rumqopg0	414	5	(	(	-LRB-
cord-312486-rumqopg0	414	6	1931	1931	CD
cord-312486-rumqopg0	414	7	)	)	-RRB-
cord-312486-rumqopg0	414	8	.	.	.
cord-312486-rumqopg0	415	1	In	in	IN
cord-312486-rumqopg0	415	2	this	this	DT
cord-312486-rumqopg0	415	3	version	version	NN
cord-312486-rumqopg0	415	4	,	,	,
cord-312486-rumqopg0	415	5	the	the	DT
cord-312486-rumqopg0	415	6	landscape	landscape	NN
cord-312486-rumqopg0	415	7	from	from	IN
cord-312486-rumqopg0	415	8	the	the	DT
cord-312486-rumqopg0	415	9	first	first	JJ
cord-312486-rumqopg0	415	10	painting	painting	NN
cord-312486-rumqopg0	415	11	has	have	VBZ
cord-312486-rumqopg0	415	12	been	be	VBN
cord-312486-rumqopg0	415	13	engulfed	engulf	VBN
cord-312486-rumqopg0	415	14	by	by	IN
cord-312486-rumqopg0	415	15	water	water	NN
cord-312486-rumqopg0	415	16	.	.	.
cord-312486-rumqopg0	416	1	Disintegration	disintegration	NN
cord-312486-rumqopg0	416	2	of	of	IN
cord-312486-rumqopg0	416	3	objects	object	NNS
cord-312486-rumqopg0	416	4	is	be	VBZ
cord-312486-rumqopg0	416	5	occurring	occur	VBG
cord-312486-rumqopg0	416	6	above	above	RB
cord-312486-rumqopg0	416	7	and	and	CC
cord-312486-rumqopg0	416	8	below	below	IN
cord-312486-rumqopg0	416	9	the	the	DT
cord-312486-rumqopg0	416	10	water	water	NN
cord-312486-rumqopg0	416	11	.	.	.
cord-312486-rumqopg0	417	1	The	the	DT
cord-312486-rumqopg0	417	2	block	block	NN
cord-312486-rumqopg0	417	3	and	and	CC
cord-312486-rumqopg0	417	4	plane	plane	NN
cord-312486-rumqopg0	417	5	from	from	IN
cord-312486-rumqopg0	417	6	his	-PRON-	PRP$
cord-312486-rumqopg0	417	7	original	original	JJ
cord-312486-rumqopg0	417	8	(	(	-LRB-
cord-312486-rumqopg0	417	9	LT	LT	NNP
cord-312486-rumqopg0	417	10	)	)	-RRB-
cord-312486-rumqopg0	417	11	have	have	VBP
cord-312486-rumqopg0	417	12	now	now	RB
cord-312486-rumqopg0	417	13	been	be	VBN
cord-312486-rumqopg0	417	14	separated	separate	VBN
cord-312486-rumqopg0	417	15	into	into	IN
cord-312486-rumqopg0	417	16	brick	brick	NN
cord-312486-rumqopg0	417	17	-	-	HYPH
cord-312486-rumqopg0	417	18	like	like	JJ
cord-312486-rumqopg0	417	19	objects	object	NNS
cord-312486-rumqopg0	417	20	that	that	WDT
cord-312486-rumqopg0	417	21	float	float	VBP
cord-312486-rumqopg0	417	22	.	.	.
cord-312486-rumqopg0	418	1	Some	some	DT
cord-312486-rumqopg0	418	2	of	of	IN
cord-312486-rumqopg0	418	3	the	the	DT
cord-312486-rumqopg0	418	4	bricks	brick	NNS
cord-312486-rumqopg0	418	5	on	on	IN
cord-312486-rumqopg0	418	6	the	the	DT
cord-312486-rumqopg0	418	7	left	left	JJ
cord-312486-rumqopg0	418	8	side	side	NN
cord-312486-rumqopg0	418	9	of	of	IN
cord-312486-rumqopg0	418	10	the	the	DT
cord-312486-rumqopg0	418	11	painting	painting	NN
cord-312486-rumqopg0	418	12	begin	begin	VBP
cord-312486-rumqopg0	418	13	to	to	TO
cord-312486-rumqopg0	418	14	disintegrate	disintegrate	VB
cord-312486-rumqopg0	418	15	.	.	.
cord-312486-rumqopg0	419	1	A	a	DT
cord-312486-rumqopg0	419	2	watch	watch	NN
cord-312486-rumqopg0	419	3	beneath	beneath	IN
cord-312486-rumqopg0	419	4	the	the	DT
cord-312486-rumqopg0	419	5	water	water	NN
cord-312486-rumqopg0	419	6	is	be	VBZ
cord-312486-rumqopg0	419	7	coming	come	VBG
cord-312486-rumqopg0	419	8	to	to	IN
cord-312486-rumqopg0	419	9	pieces	piece	NNS
cord-312486-rumqopg0	419	10	and	and	CC
cord-312486-rumqopg0	419	11	another	another	DT
cord-312486-rumqopg0	419	12	one	one	NN
cord-312486-rumqopg0	419	13	that	that	WDT
cord-312486-rumqopg0	419	14	sunk	sink	VBD
cord-312486-rumqopg0	419	15	beneath	beneath	IN
cord-312486-rumqopg0	419	16	the	the	DT
cord-312486-rumqopg0	419	17	layer	layer	NN
cord-312486-rumqopg0	419	18	of	of	IN
cord-312486-rumqopg0	419	19	bricks	brick	NNS
cord-312486-rumqopg0	419	20	,	,	,
cord-312486-rumqopg0	419	21	leaves	leave	VBZ
cord-312486-rumqopg0	419	22	bits	bit	NNS
cord-312486-rumqopg0	419	23	of	of	IN
cord-312486-rumqopg0	419	24	debris	debris	NN
cord-312486-rumqopg0	419	25	behind	behind	RB
cord-312486-rumqopg0	419	26	.	.	.
cord-312486-rumqopg0	420	1	While	while	IN
cord-312486-rumqopg0	420	2	Persistence	persistence	NN
cord-312486-rumqopg0	420	3	of	of	IN
cord-312486-rumqopg0	420	4	Memory	memory	NN
cord-312486-rumqopg0	420	5	(	(	-LRB-
cord-312486-rumqopg0	420	6	LT	LT	NNP
cord-312486-rumqopg0	420	7	)	)	-RRB-
cord-312486-rumqopg0	420	8	symbolizes	symbolize	VBZ
cord-312486-rumqopg0	420	9	the	the	DT
cord-312486-rumqopg0	420	10	importance	importance	NN
cord-312486-rumqopg0	420	11	of	of	IN
cord-312486-rumqopg0	420	12	immunological	immunological	JJ
cord-312486-rumqopg0	420	13	memory	memory	NN
cord-312486-rumqopg0	420	14	as	as	IN
cord-312486-rumqopg0	420	15	cornerstone	cornerstone	NN
cord-312486-rumqopg0	420	16	of	of	IN
cord-312486-rumqopg0	420	17	adaptive	adaptive	JJ
cord-312486-rumqopg0	420	18	immunity	immunity	NN
cord-312486-rumqopg0	420	19	,	,	,
cord-312486-rumqopg0	420	20	the	the	DT
cord-312486-rumqopg0	420	21	Disintegration	disintegration	NN
cord-312486-rumqopg0	420	22	of	of	IN
cord-312486-rumqopg0	420	23	the	the	DT
cord-312486-rumqopg0	420	24	Persistence	Persistence	NNP
cord-312486-rumqopg0	420	25	of	of	IN
cord-312486-rumqopg0	420	26	Memory	Memory	NNP
cord-312486-rumqopg0	420	27	(	(	-LRB-
cord-312486-rumqopg0	420	28	RT	RT	NNP
cord-312486-rumqopg0	420	29	)	)	-RRB-
cord-312486-rumqopg0	420	30	is	be	VBZ
cord-312486-rumqopg0	420	31	a	a	DT
cord-312486-rumqopg0	420	32	metaphor	metaphor	NN
cord-312486-rumqopg0	420	33	for	for	IN
cord-312486-rumqopg0	420	34	Gorbalenya	Gorbalenya	NNP
cord-312486-rumqopg0	420	35	,	,	,
cord-312486-rumqopg0	420	36	and	and	CC
cord-312486-rumqopg0	420	37	the	the	DT
cord-312486-rumqopg0	420	38	Coronaviridae	Coronaviridae	NNP
cord-312486-rumqopg0	420	39	Study	Study	NNP
cord-312486-rumqopg0	420	40	Group	Group	NNP
cord-312486-rumqopg0	420	41	of	of	IN
cord-312486-rumqopg0	420	42	the	the	DT
cord-312486-rumqopg0	420	43	International	International	NNP
cord-312486-rumqopg0	420	44	Committee	Committee	NNP
cord-312486-rumqopg0	420	45	on	on	IN
cord-312486-rumqopg0	420	46	Taxonomy	Taxonomy	NNP
cord-312486-rumqopg0	420	47	of	of	IN
cord-312486-rumqopg0	420	48	Viruses	Viruses	NNPS
cord-312486-rumqopg0	420	49	,	,	,
cord-312486-rumqopg0	420	50	The	the	DT
cord-312486-rumqopg0	420	51	species	specie	NNS
cord-312486-rumqopg0	420	52	severe	severe	JJ
cord-312486-rumqopg0	420	53	acute	acute	JJ
cord-312486-rumqopg0	420	54	respiratory	respiratory	JJ
cord-312486-rumqopg0	420	55	syndrome	syndrome	NN
cord-312486-rumqopg0	420	56	-	-	HYPH
cord-312486-rumqopg0	420	57	related	relate	VBN
cord-312486-rumqopg0	420	58	coronavirus	coronavirus	NN
cord-312486-rumqopg0	420	59	:	:	:
cord-312486-rumqopg0	420	60	classifying	classify	VBG
cord-312486-rumqopg0	420	61	2019-nCoV	2019-ncov	CD
cord-312486-rumqopg0	420	62	and	and	CC
cord-312486-rumqopg0	420	63	naming	name	VBG
cord-312486-rumqopg0	420	64	it	-PRON-	PRP
cord-312486-rumqopg0	421	1	SARS	SARS	NNP
cord-312486-rumqopg0	421	2	-	-	HYPH
cord-312486-rumqopg0	421	3	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	422	1	The	the	DT
cord-312486-rumqopg0	422	2	molecular	molecular	JJ
cord-312486-rumqopg0	422	3	biology	biology	NN
cord-312486-rumqopg0	422	4	of	of	IN
cord-312486-rumqopg0	422	5	coronaviruses	coronaviruse	NNS
cord-312486-rumqopg0	423	1	Coronaviruses	coronaviruse	NNS
cord-312486-rumqopg0	423	2	:	:	:
cord-312486-rumqopg0	423	3	an	an	DT
cord-312486-rumqopg0	423	4	overview	overview	NN
cord-312486-rumqopg0	423	5	of	of	IN
cord-312486-rumqopg0	423	6	their	-PRON-	PRP$
cord-312486-rumqopg0	423	7	replication	replication	NN
cord-312486-rumqopg0	423	8	and	and	CC
cord-312486-rumqopg0	423	9	pathogenesis	pathogenesis	NN
cord-312486-rumqopg0	424	1	A	a	DT
cord-312486-rumqopg0	424	2	new	new	JJ
cord-312486-rumqopg0	424	3	virus	virus	NN
cord-312486-rumqopg0	424	4	isolated	isolate	VBN
cord-312486-rumqopg0	424	5	from	from	IN
cord-312486-rumqopg0	424	6	the	the	DT
cord-312486-rumqopg0	424	7	human	human	JJ
cord-312486-rumqopg0	424	8	respiratory	respiratory	JJ
cord-312486-rumqopg0	424	9	tract	tract	NN
cord-312486-rumqopg0	424	10	Recovery	recovery	NN
cord-312486-rumqopg0	424	11	in	in	IN
cord-312486-rumqopg0	424	12	tracheal	tracheal	JJ
cord-312486-rumqopg0	424	13	organ	organ	NN
cord-312486-rumqopg0	424	14	cultures	culture	NNS
cord-312486-rumqopg0	424	15	of	of	IN
cord-312486-rumqopg0	424	16	novel	novel	NN
cord-312486-rumqopg0	424	17	viruses	virus	NNS
cord-312486-rumqopg0	424	18	from	from	IN
cord-312486-rumqopg0	424	19	patients	patient	NNS
cord-312486-rumqopg0	424	20	with	with	IN
cord-312486-rumqopg0	424	21	respiratory	respiratory	JJ
cord-312486-rumqopg0	424	22	disease	disease	NN
cord-312486-rumqopg0	424	23	Identification	identification	NN
cord-312486-rumqopg0	424	24	of	of	IN
cord-312486-rumqopg0	424	25	a	a	DT
cord-312486-rumqopg0	424	26	new	new	JJ
cord-312486-rumqopg0	424	27	human	human	JJ
cord-312486-rumqopg0	424	28	coronavirus	coronavirus	NN
cord-312486-rumqopg0	424	29	Phylogenetic	Phylogenetic	NNP
cord-312486-rumqopg0	424	30	and	and	CC
cord-312486-rumqopg0	424	31	recombination	recombination	NN
cord-312486-rumqopg0	424	32	analysis	analysis	NN
cord-312486-rumqopg0	424	33	of	of	IN
cord-312486-rumqopg0	424	34	coronavirus	coronavirus	NN
cord-312486-rumqopg0	424	35	HKU1	HKU1	NNP
cord-312486-rumqopg0	424	36	,	,	,
cord-312486-rumqopg0	424	37	a	a	DT
cord-312486-rumqopg0	424	38	novel	novel	JJ
cord-312486-rumqopg0	424	39	coronavirus	coronavirus	NN
cord-312486-rumqopg0	424	40	from	from	IN
cord-312486-rumqopg0	424	41	patients	patient	NNS
cord-312486-rumqopg0	424	42	with	with	IN
cord-312486-rumqopg0	424	43	pneumonia	pneumonia	NN
cord-312486-rumqopg0	424	44	Hosts	Hosts	NNPS
cord-312486-rumqopg0	424	45	and	and	CC
cord-312486-rumqopg0	424	46	Sources	Sources	NNPS
cord-312486-rumqopg0	424	47	of	of	IN
cord-312486-rumqopg0	424	48	Endemic	Endemic	NNP
cord-312486-rumqopg0	424	49	Human	Human	NNP
cord-312486-rumqopg0	424	50	Coronaviruses	Coronaviruses	NNPS
cord-312486-rumqopg0	425	1	A	a	DT
cord-312486-rumqopg0	425	2	novel	novel	JJ
cord-312486-rumqopg0	425	3	coronavirus	coronavirus	NN
cord-312486-rumqopg0	425	4	associated	associate	VBN
cord-312486-rumqopg0	425	5	with	with	IN
cord-312486-rumqopg0	425	6	severe	severe	JJ
cord-312486-rumqopg0	425	7	acute	acute	JJ
cord-312486-rumqopg0	425	8	respiratory	respiratory	JJ
cord-312486-rumqopg0	425	9	syndrome	syndrome	NN
cord-312486-rumqopg0	425	10	Isolation	isolation	NN
cord-312486-rumqopg0	425	11	of	of	IN
cord-312486-rumqopg0	425	12	a	a	DT
cord-312486-rumqopg0	425	13	novel	novel	JJ
cord-312486-rumqopg0	425	14	coronavirus	coronavirus	NN
cord-312486-rumqopg0	425	15	from	from	IN
cord-312486-rumqopg0	425	16	a	a	DT
cord-312486-rumqopg0	425	17	man	man	NN
cord-312486-rumqopg0	425	18	with	with	IN
cord-312486-rumqopg0	425	19	pneumonia	pneumonia	NN
cord-312486-rumqopg0	425	20	in	in	IN
cord-312486-rumqopg0	425	21	Saudi	Saudi	NNP
cord-312486-rumqopg0	425	22	Arabia	Arabia	NNP
cord-312486-rumqopg0	425	23	Genomic	Genomic	NNP
cord-312486-rumqopg0	425	24	characterization	characterization	NN
cord-312486-rumqopg0	425	25	and	and	CC
cord-312486-rumqopg0	425	26	epidemiology	epidemiology	NN
cord-312486-rumqopg0	425	27	of	of	IN
cord-312486-rumqopg0	425	28	2019	2019	CD
cord-312486-rumqopg0	425	29	novel	novel	JJ
cord-312486-rumqopg0	425	30	coronavirus	coronavirus	NN
cord-312486-rumqopg0	425	31	:	:	:
cord-312486-rumqopg0	425	32	implication	implication	NN
cord-312486-rumqopg0	425	33	for	for	IN
cord-312486-rumqopg0	425	34	virus	virus	NN
cord-312486-rumqopg0	425	35	origin	origin	NN
cord-312486-rumqopg0	425	36	and	and	CC
cord-312486-rumqopg0	425	37	receptor	receptor	NN
cord-312486-rumqopg0	425	38	binding	bind	VBG
cord-312486-rumqopg0	425	39	Isolation	isolation	NN
cord-312486-rumqopg0	425	40	and	and	CC
cord-312486-rumqopg0	425	41	characterization	characterization	NN
cord-312486-rumqopg0	425	42	of	of	IN
cord-312486-rumqopg0	425	43	a	a	DT
cord-312486-rumqopg0	425	44	bat	bat	NN
cord-312486-rumqopg0	425	45	SARS	SARS	NNP
cord-312486-rumqopg0	425	46	-	-	HYPH
cord-312486-rumqopg0	425	47	like	like	JJ
cord-312486-rumqopg0	425	48	coronavirus	coronavirus	NN
cord-312486-rumqopg0	425	49	that	that	WDT
cord-312486-rumqopg0	425	50	uses	use	VBZ
cord-312486-rumqopg0	425	51	the	the	DT
cord-312486-rumqopg0	425	52	ACE2	ACE2	NNP
cord-312486-rumqopg0	425	53	receptor	receptor	NN
cord-312486-rumqopg0	425	54	SARS	SARS	NNP
cord-312486-rumqopg0	425	55	and	and	CC
cord-312486-rumqopg0	425	56	MERS	MERS	NNP
cord-312486-rumqopg0	425	57	:	:	:
cord-312486-rumqopg0	425	58	recent	recent	JJ
cord-312486-rumqopg0	425	59	insights	insight	NNS
cord-312486-rumqopg0	425	60	into	into	IN
cord-312486-rumqopg0	425	61	emerging	emerge	VBG
cord-312486-rumqopg0	425	62	coronaviruses	coronaviruse	NNS
cord-312486-rumqopg0	426	1	A	a	DT
cord-312486-rumqopg0	426	2	pneumonia	pneumonia	NN
cord-312486-rumqopg0	426	3	outbreak	outbreak	NN
cord-312486-rumqopg0	426	4	associated	associate	VBN
cord-312486-rumqopg0	426	5	with	with	IN
cord-312486-rumqopg0	426	6	a	a	DT
cord-312486-rumqopg0	426	7	new	new	JJ
cord-312486-rumqopg0	426	8	coronavirus	coronavirus	NN
cord-312486-rumqopg0	426	9	of	of	IN
cord-312486-rumqopg0	426	10	probable	probable	JJ
cord-312486-rumqopg0	426	11	bat	bat	NN
cord-312486-rumqopg0	426	12	origin	origin	NN
cord-312486-rumqopg0	427	1	The	the	DT
cord-312486-rumqopg0	427	2	proximal	proximal	JJ
cord-312486-rumqopg0	427	3	origin	origin	NN
cord-312486-rumqopg0	427	4	of	of	IN
cord-312486-rumqopg0	427	5	SARS	SARS	NNP
cord-312486-rumqopg0	427	6	-	-	HYPH
cord-312486-rumqopg0	427	7	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	427	8	Insights	Insights	NNPS
cord-312486-rumqopg0	427	9	into	into	IN
cord-312486-rumqopg0	427	10	RNA	RNA	NNP
cord-312486-rumqopg0	427	11	synthesis	synthesis	NN
cord-312486-rumqopg0	427	12	,	,	,
cord-312486-rumqopg0	427	13	capping	capping	NN
cord-312486-rumqopg0	427	14	,	,	,
cord-312486-rumqopg0	427	15	and	and	CC
cord-312486-rumqopg0	427	16	proofreading	proofreading	NN
cord-312486-rumqopg0	427	17	mechanisms	mechanism	NNS
cord-312486-rumqopg0	427	18	of	of	IN
cord-312486-rumqopg0	427	19	SARS	SARS	NNP
cord-312486-rumqopg0	427	20	-	-	HYPH
cord-312486-rumqopg0	427	21	coronavirus	coronavirus	NN
cord-312486-rumqopg0	428	1	The	the	DT
cord-312486-rumqopg0	428	2	S	S	NNP
cord-312486-rumqopg0	428	3	proteins	protein	NNS
cord-312486-rumqopg0	428	4	of	of	IN
cord-312486-rumqopg0	428	5	human	human	JJ
cord-312486-rumqopg0	428	6	coronavirus	coronavirus	NN
cord-312486-rumqopg0	428	7	NL63	NL63	NNP
cord-312486-rumqopg0	428	8	and	and	CC
cord-312486-rumqopg0	428	9	severe	severe	JJ
cord-312486-rumqopg0	428	10	acute	acute	JJ
cord-312486-rumqopg0	428	11	respiratory	respiratory	JJ
cord-312486-rumqopg0	428	12	syndrome	syndrome	NN
cord-312486-rumqopg0	428	13	coronavirus	coronavirus	NN
cord-312486-rumqopg0	428	14	bind	bind	VBP
cord-312486-rumqopg0	428	15	overlapping	overlap	VBG
cord-312486-rumqopg0	428	16	regions	region	NNS
cord-312486-rumqopg0	428	17	of	of	IN
cord-312486-rumqopg0	428	18	ACE2	ACE2	NNP
cord-312486-rumqopg0	428	19	SARS	SARS	NNP
cord-312486-rumqopg0	428	20	-	-	HYPH
cord-312486-rumqopg0	428	21	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	428	22	Cell	cell	NN
cord-312486-rumqopg0	428	23	entry	entry	NN
cord-312486-rumqopg0	428	24	depends	depend	VBZ
cord-312486-rumqopg0	428	25	on	on	IN
cord-312486-rumqopg0	428	26	ACE2	ACE2	NNP
cord-312486-rumqopg0	428	27	and	and	CC
cord-312486-rumqopg0	428	28	TMPRSS2	TMPRSS2	NNP
cord-312486-rumqopg0	428	29	and	and	CC
cord-312486-rumqopg0	428	30	is	be	VBZ
cord-312486-rumqopg0	428	31	blocked	block	VBN
cord-312486-rumqopg0	428	32	by	by	IN
cord-312486-rumqopg0	428	33	a	a	DT
cord-312486-rumqopg0	428	34	clinically	clinically	RB
cord-312486-rumqopg0	428	35	proven	prove	VBN
cord-312486-rumqopg0	428	36	protease	protease	NN
cord-312486-rumqopg0	428	37	inhibitor	inhibitor	NN
cord-312486-rumqopg0	428	38	Structure	Structure	NNP
cord-312486-rumqopg0	428	39	,	,	,
cord-312486-rumqopg0	428	40	function	function	NN
cord-312486-rumqopg0	428	41	and	and	CC
cord-312486-rumqopg0	428	42	antigenicity	antigenicity	NN
cord-312486-rumqopg0	428	43	of	of	IN
cord-312486-rumqopg0	428	44	the	the	DT
cord-312486-rumqopg0	428	45	SARS	SARS	NNP
cord-312486-rumqopg0	428	46	-	-	HYPH
cord-312486-rumqopg0	428	47	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	428	48	spike	spike	NN
cord-312486-rumqopg0	428	49	glycoprotein	glycoprotein	NN
cord-312486-rumqopg0	428	50	Cryo	cryo	NN
cord-312486-rumqopg0	428	51	-	-	HYPH
cord-312486-rumqopg0	428	52	EM	EM	NNP
cord-312486-rumqopg0	428	53	structure	structure	NN
cord-312486-rumqopg0	428	54	of	of	IN
cord-312486-rumqopg0	428	55	the	the	DT
cord-312486-rumqopg0	428	56	2019-nCoV	2019-ncov	CD
cord-312486-rumqopg0	428	57	spike	spike	NN
cord-312486-rumqopg0	428	58	in	in	IN
cord-312486-rumqopg0	428	59	the	the	DT
cord-312486-rumqopg0	428	60	prefusion	prefusion	NN
cord-312486-rumqopg0	428	61	conformation	conformation	NNP
cord-312486-rumqopg0	428	62	Structure	Structure	NNP
cord-312486-rumqopg0	428	63	of	of	IN
cord-312486-rumqopg0	428	64	the	the	DT
cord-312486-rumqopg0	428	65	hemagglutinin	hemagglutinin	NN
cord-312486-rumqopg0	428	66	precursor	precursor	NN
cord-312486-rumqopg0	428	67	cleavage	cleavage	NN
cord-312486-rumqopg0	428	68	site	site	NN
cord-312486-rumqopg0	428	69	,	,	,
cord-312486-rumqopg0	428	70	a	a	DT
cord-312486-rumqopg0	428	71	determinant	determinant	NN
cord-312486-rumqopg0	428	72	of	of	IN
cord-312486-rumqopg0	428	73	influenza	influenza	NN
cord-312486-rumqopg0	428	74	pathogenicity	pathogenicity	NN
cord-312486-rumqopg0	428	75	and	and	CC
cord-312486-rumqopg0	428	76	the	the	DT
cord-312486-rumqopg0	428	77	origin	origin	NN
cord-312486-rumqopg0	428	78	of	of	IN
cord-312486-rumqopg0	428	79	the	the	DT
cord-312486-rumqopg0	428	80	labile	labile	JJ
cord-312486-rumqopg0	428	81	conformation	conformation	NN
cord-312486-rumqopg0	429	1	The	the	DT
cord-312486-rumqopg0	429	2	global	global	JJ
cord-312486-rumqopg0	429	3	phosphorylation	phosphorylation	NN
cord-312486-rumqopg0	429	4	landscape	landscape	NN
cord-312486-rumqopg0	429	5	of	of	IN
cord-312486-rumqopg0	429	6	SARS	SARS	NNP
cord-312486-rumqopg0	429	7	-	-	HYPH
cord-312486-rumqopg0	429	8	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	429	9	infection	infection	NN
cord-312486-rumqopg0	429	10	Filopodia	Filopodia	NNP
cord-312486-rumqopg0	429	11	and	and	CC
cord-312486-rumqopg0	429	12	Viruses	Viruses	NNPS
cord-312486-rumqopg0	429	13	:	:	:
cord-312486-rumqopg0	429	14	an	an	DT
cord-312486-rumqopg0	429	15	analysis	analysis	NN
cord-312486-rumqopg0	429	16	of	of	IN
cord-312486-rumqopg0	429	17	membrane	membrane	NN
cord-312486-rumqopg0	429	18	processes	process	NNS
cord-312486-rumqopg0	429	19	in	in	IN
cord-312486-rumqopg0	429	20	entry	entry	NN
cord-312486-rumqopg0	429	21	mechanisms	mechanism	NNS
cord-312486-rumqopg0	429	22	Spiking	spike	VBG
cord-312486-rumqopg0	429	23	pandemic	pandemic	NN
cord-312486-rumqopg0	429	24	potential	potential	NN
cord-312486-rumqopg0	429	25	:	:	:
cord-312486-rumqopg0	429	26	structural	structural	JJ
cord-312486-rumqopg0	429	27	and	and	CC
cord-312486-rumqopg0	429	28	immunological	immunological	JJ
cord-312486-rumqopg0	429	29	aspects	aspect	NNS
cord-312486-rumqopg0	429	30	of	of	IN
cord-312486-rumqopg0	429	31	SARS	SARS	NNP
cord-312486-rumqopg0	429	32	-	-	HYPH
cord-312486-rumqopg0	429	33	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	430	1	COVID-19	covid-19	VB
cord-312486-rumqopg0	430	2	:	:	:
cord-312486-rumqopg0	430	3	Immunology	immunology	NN
cord-312486-rumqopg0	430	4	and	and	CC
cord-312486-rumqopg0	430	5	treatment	treatment	NN
cord-312486-rumqopg0	430	6	options	option	NNS
cord-312486-rumqopg0	431	1	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	431	2	pathophysiology	pathophysiology	NN
cord-312486-rumqopg0	431	3	:	:	:
cord-312486-rumqopg0	432	1	A	a	DT
cord-312486-rumqopg0	432	2	review	review	NN
cord-312486-rumqopg0	433	1	Tracking	tracking	NN
cord-312486-rumqopg0	433	2	changes	change	NNS
cord-312486-rumqopg0	433	3	in	in	IN
cord-312486-rumqopg0	433	4	SARS	SARS	NNP
cord-312486-rumqopg0	433	5	-	-	HYPH
cord-312486-rumqopg0	433	6	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	433	7	Spike	spike	NN
cord-312486-rumqopg0	433	8	:	:	:
cord-312486-rumqopg0	433	9	evidence	evidence	NN
cord-312486-rumqopg0	433	10	that	that	IN
cord-312486-rumqopg0	433	11	D614	d614	CD
cord-312486-rumqopg0	433	12	G	g	NN
cord-312486-rumqopg0	433	13	increases	increase	VBZ
cord-312486-rumqopg0	433	14	infectivity	infectivity	NN
cord-312486-rumqopg0	433	15	of	of	IN
cord-312486-rumqopg0	433	16	the	the	DT
cord-312486-rumqopg0	433	17	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	433	18	virus	virus	NN
cord-312486-rumqopg0	433	19	On	on	IN
cord-312486-rumqopg0	433	20	the	the	DT
cord-312486-rumqopg0	433	21	origin	origin	NN
cord-312486-rumqopg0	433	22	and	and	CC
cord-312486-rumqopg0	433	23	continuing	continue	VBG
cord-312486-rumqopg0	433	24	evolution	evolution	NN
cord-312486-rumqopg0	433	25	of	of	IN
cord-312486-rumqopg0	433	26	SARS	SARS	NNP
cord-312486-rumqopg0	433	27	-	-	HYPH
cord-312486-rumqopg0	433	28	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	433	29	Viral	Viral	NNP
cord-312486-rumqopg0	433	30	and	and	CC
cord-312486-rumqopg0	433	31	host	host	NN
cord-312486-rumqopg0	433	32	factors	factor	NNS
cord-312486-rumqopg0	433	33	related	relate	VBN
cord-312486-rumqopg0	433	34	to	to	IN
cord-312486-rumqopg0	433	35	the	the	DT
cord-312486-rumqopg0	433	36	clinical	clinical	JJ
cord-312486-rumqopg0	433	37	outcome	outcome	NN
cord-312486-rumqopg0	433	38	of	of	IN
cord-312486-rumqopg0	433	39	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	433	40	The	the	DT
cord-312486-rumqopg0	433	41	D614	d614	NN
cord-312486-rumqopg0	433	42	G	g	NN
cord-312486-rumqopg0	433	43	mutation	mutation	NN
cord-312486-rumqopg0	433	44	of	of	IN
cord-312486-rumqopg0	433	45	SARS	SARS	NNP
cord-312486-rumqopg0	433	46	-	-	HYPH
cord-312486-rumqopg0	433	47	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	433	48	spike	spike	NN
cord-312486-rumqopg0	433	49	protein	protein	NN
cord-312486-rumqopg0	433	50	enhances	enhance	VBZ
cord-312486-rumqopg0	433	51	viral	viral	JJ
cord-312486-rumqopg0	433	52	infectivity	infectivity	NN
cord-312486-rumqopg0	433	53	and	and	CC
cord-312486-rumqopg0	433	54	decreases	decrease	VBZ
cord-312486-rumqopg0	433	55	neutralization	neutralization	NN
cord-312486-rumqopg0	433	56	sensitivity	sensitivity	NN
cord-312486-rumqopg0	433	57	to	to	IN
cord-312486-rumqopg0	433	58	J	J	NNP
cord-312486-rumqopg0	433	59	o	o	NN
cord-312486-rumqopg0	433	60	u	u	NN
cord-312486-rumqopg0	433	61	r	r	NN
cord-312486-rumqopg0	433	62	n	n	NN
cord-312486-rumqopg0	433	63	a	a	DT
cord-312486-rumqopg0	433	64	l	l	NN
cord-312486-rumqopg0	433	65	P	p	NN
cord-312486-rumqopg0	433	66	r	r	NN
cord-312486-rumqopg0	433	67	e	e	NN
cord-312486-rumqopg0	433	68	-p	-p	NN
cord-312486-rumqopg0	434	1	r	r	NN
cord-312486-rumqopg0	434	2	o	o	NN
cord-312486-rumqopg0	434	3	o	o	NN
cord-312486-rumqopg0	434	4	f	f	NNP
cord-312486-rumqopg0	434	5	Journal	Journal	NNP
cord-312486-rumqopg0	434	6	Pre	Pre	NNP
cord-312486-rumqopg0	434	7	-	-	JJ
cord-312486-rumqopg0	434	8	proof	proof	JJ
cord-312486-rumqopg0	434	9	individual	individual	JJ
cord-312486-rumqopg0	434	10	convalescent	convalescent	NN
cord-312486-rumqopg0	434	11	sera	sera	NNP
cord-312486-rumqopg0	435	1	The	the	DT
cord-312486-rumqopg0	435	2	D614	d614	NN
cord-312486-rumqopg0	435	3	G	g	NN
cord-312486-rumqopg0	435	4	mutation	mutation	NN
cord-312486-rumqopg0	435	5	in	in	IN
cord-312486-rumqopg0	435	6	the	the	DT
cord-312486-rumqopg0	435	7	SARS	SARS	NNP
cord-312486-rumqopg0	435	8	-	-	HYPH
cord-312486-rumqopg0	435	9	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	435	10	spike	spike	NN
cord-312486-rumqopg0	435	11	protein	protein	NN
cord-312486-rumqopg0	435	12	reduces	reduce	VBZ
cord-312486-rumqopg0	435	13	S1	s1	NN
cord-312486-rumqopg0	435	14	shedding	shedding	NN
cord-312486-rumqopg0	435	15	and	and	CC
cord-312486-rumqopg0	435	16	increases	increase	VBZ
cord-312486-rumqopg0	435	17	infectivity	infectivity	NN
cord-312486-rumqopg0	436	1	A	a	DT
cord-312486-rumqopg0	436	2	Unique	Unique	NNP
cord-312486-rumqopg0	436	3	Clade	Clade	NNP
cord-312486-rumqopg0	436	4	of	of	IN
cord-312486-rumqopg0	436	5	SARS	SARS	NNP
cord-312486-rumqopg0	436	6	-	-	HYPH
cord-312486-rumqopg0	436	7	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	436	8	Viruses	Viruses	NNPS
cord-312486-rumqopg0	436	9	is	be	VBZ
cord-312486-rumqopg0	436	10	Associated	associate	VBN
cord-312486-rumqopg0	436	11	with	with	IN
cord-312486-rumqopg0	436	12	Lower	low	JJR
cord-312486-rumqopg0	436	13	Viral	Viral	NNP
cord-312486-rumqopg0	436	14	Loads	Loads	NNPS
cord-312486-rumqopg0	436	15	in	in	IN
cord-312486-rumqopg0	436	16	Patient	Patient	NNP
cord-312486-rumqopg0	436	17	Upper	Upper	NNP
cord-312486-rumqopg0	436	18	Airways	Airways	NNPS
cord-312486-rumqopg0	437	1	SARS	SARS	NNP
cord-312486-rumqopg0	437	2	-	-	HYPH
cord-312486-rumqopg0	437	3	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	437	4	viral	viral	JJ
cord-312486-rumqopg0	437	5	spike	spike	NN
cord-312486-rumqopg0	437	6	G614	g614	NN
cord-312486-rumqopg0	437	7	mutation	mutation	NN
cord-312486-rumqopg0	437	8	exhibits	exhibit	VBZ
cord-312486-rumqopg0	437	9	higher	high	JJR
cord-312486-rumqopg0	437	10	case	case	NN
cord-312486-rumqopg0	437	11	fatality	fatality	NN
cord-312486-rumqopg0	437	12	rate	rate	NN
cord-312486-rumqopg0	437	13	Receptor	receptor	NN
cord-312486-rumqopg0	437	14	and	and	CC
cord-312486-rumqopg0	437	15	viral	viral	JJ
cord-312486-rumqopg0	437	16	determinants	determinant	NNS
cord-312486-rumqopg0	437	17	of	of	IN
cord-312486-rumqopg0	437	18	SARS	SARS	NNP
cord-312486-rumqopg0	437	19	-	-	HYPH
cord-312486-rumqopg0	437	20	coronavirus	coronavirus	NN
cord-312486-rumqopg0	437	21	adaptation	adaptation	NN
cord-312486-rumqopg0	437	22	to	to	IN
cord-312486-rumqopg0	437	23	human	human	JJ
cord-312486-rumqopg0	437	24	ACE2	ACE2	NNP
cord-312486-rumqopg0	437	25	Comparative	Comparative	NNP
cord-312486-rumqopg0	437	26	genetic	genetic	JJ
cord-312486-rumqopg0	437	27	analysis	analysis	NN
cord-312486-rumqopg0	437	28	of	of	IN
cord-312486-rumqopg0	437	29	the	the	DT
cord-312486-rumqopg0	437	30	novel	novel	JJ
cord-312486-rumqopg0	437	31	coronavirus	coronavirus	NN
cord-312486-rumqopg0	437	32	(	(	-LRB-
cord-312486-rumqopg0	437	33	2019-nCoV	2019-ncov	CD
cord-312486-rumqopg0	437	34	/	/	SYM
cord-312486-rumqopg0	437	35	SARS	SARS	NNP
cord-312486-rumqopg0	437	36	-	-	HYPH
cord-312486-rumqopg0	437	37	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	437	38	)	)	-RRB-
cord-312486-rumqopg0	437	39	receptor	receptor	NN
cord-312486-rumqopg0	437	40	ACE2	ACE2	NNP
cord-312486-rumqopg0	437	41	in	in	IN
cord-312486-rumqopg0	437	42	different	different	JJ
cord-312486-rumqopg0	437	43	populations	population	NNS
cord-312486-rumqopg0	437	44	Age	age	NN
cord-312486-rumqopg0	437	45	-	-	HYPH
cord-312486-rumqopg0	437	46	dependent	dependent	JJ
cord-312486-rumqopg0	437	47	effects	effect	NNS
cord-312486-rumqopg0	437	48	in	in	IN
cord-312486-rumqopg0	437	49	the	the	DT
cord-312486-rumqopg0	437	50	transmission	transmission	NN
cord-312486-rumqopg0	437	51	and	and	CC
cord-312486-rumqopg0	437	52	control	control	NN
cord-312486-rumqopg0	437	53	of	of	IN
cord-312486-rumqopg0	437	54	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	437	55	epidemics	epidemic	NNS
cord-312486-rumqopg0	437	56	Nasal	Nasal	NNP
cord-312486-rumqopg0	437	57	gene	gene	NN
cord-312486-rumqopg0	437	58	expression	expression	NN
cord-312486-rumqopg0	437	59	of	of	IN
cord-312486-rumqopg0	437	60	angiotensin	angiotensin	NN
cord-312486-rumqopg0	437	61	-	-	HYPH
cord-312486-rumqopg0	437	62	converting	convert	VBG
cord-312486-rumqopg0	437	63	enzyme	enzyme	NN
cord-312486-rumqopg0	437	64	2	2	CD
cord-312486-rumqopg0	437	65	in	in	IN
cord-312486-rumqopg0	437	66	children	child	NNS
cord-312486-rumqopg0	437	67	and	and	CC
cord-312486-rumqopg0	437	68	adults	adult	NNS
cord-312486-rumqopg0	437	69	Epidemiology	Epidemiology	NNP
cord-312486-rumqopg0	437	70	of	of	IN
cord-312486-rumqopg0	437	71	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	437	72	among	among	IN
cord-312486-rumqopg0	437	73	children	child	NNS
cord-312486-rumqopg0	437	74	in	in	IN
cord-312486-rumqopg0	437	75	China	China	NNP
cord-312486-rumqopg0	437	76	Angiotensin	Angiotensin	NNP
cord-312486-rumqopg0	437	77	-	-	HYPH
cord-312486-rumqopg0	437	78	converting	convert	VBG
cord-312486-rumqopg0	437	79	enzyme	enzyme	NN
cord-312486-rumqopg0	437	80	2	2	CD
cord-312486-rumqopg0	437	81	protects	protect	VBZ
cord-312486-rumqopg0	437	82	from	from	IN
cord-312486-rumqopg0	437	83	severe	severe	JJ
cord-312486-rumqopg0	437	84	acute	acute	JJ
cord-312486-rumqopg0	437	85	lung	lung	NN
cord-312486-rumqopg0	437	86	failure	failure	NN
cord-312486-rumqopg0	438	1	Angiotensin	angiotensin	NN
cord-312486-rumqopg0	438	2	-	-	HYPH
cord-312486-rumqopg0	438	3	converting	convert	VBG
cord-312486-rumqopg0	438	4	enzyme	enzyme	NN
cord-312486-rumqopg0	438	5	2	2	CD
cord-312486-rumqopg0	438	6	protects	protect	VBZ
cord-312486-rumqopg0	438	7	from	from	IN
cord-312486-rumqopg0	438	8	lethal	lethal	JJ
cord-312486-rumqopg0	438	9	avian	avian	JJ
cord-312486-rumqopg0	438	10	influenza	influenza	NN
cord-312486-rumqopg0	438	11	A	a	DT
cord-312486-rumqopg0	438	12	H5N1	H5N1	NNP
cord-312486-rumqopg0	438	13	infections	infection	NNS
cord-312486-rumqopg0	439	1	Angiotensin	angiotensin	NN
cord-312486-rumqopg0	439	2	-	-	HYPH
cord-312486-rumqopg0	439	3	converting	convert	VBG
cord-312486-rumqopg0	439	4	enzyme	enzyme	NN
cord-312486-rumqopg0	439	5	2	2	CD
cord-312486-rumqopg0	439	6	(	(	-LRB-
cord-312486-rumqopg0	439	7	ACE2	ACE2	NNP
cord-312486-rumqopg0	439	8	)	)	-RRB-
cord-312486-rumqopg0	439	9	mediates	mediate	VBZ
cord-312486-rumqopg0	439	10	influenza	influenza	NN
cord-312486-rumqopg0	439	11	H7N9	H7N9	NNP
cord-312486-rumqopg0	439	12	virus	virus	NN
cord-312486-rumqopg0	439	13	-	-	HYPH
cord-312486-rumqopg0	439	14	induced	induce	VBN
cord-312486-rumqopg0	439	15	acute	acute	JJ
cord-312486-rumqopg0	439	16	lung	lung	NN
cord-312486-rumqopg0	439	17	injury	injury	NN
cord-312486-rumqopg0	439	18	SARS	SARS	NNP
cord-312486-rumqopg0	439	19	-	-	HYPH
cord-312486-rumqopg0	439	20	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	439	21	entry	entry	NN
cord-312486-rumqopg0	439	22	factors	factor	NNS
cord-312486-rumqopg0	439	23	are	be	VBP
cord-312486-rumqopg0	439	24	highly	highly	RB
cord-312486-rumqopg0	439	25	expressed	express	VBN
cord-312486-rumqopg0	439	26	in	in	IN
cord-312486-rumqopg0	439	27	nasal	nasal	JJ
cord-312486-rumqopg0	439	28	epithelial	epithelial	JJ
cord-312486-rumqopg0	439	29	cells	cell	NNS
cord-312486-rumqopg0	439	30	together	together	RB
cord-312486-rumqopg0	439	31	with	with	IN
cord-312486-rumqopg0	439	32	innate	innate	JJ
cord-312486-rumqopg0	439	33	immune	immune	JJ
cord-312486-rumqopg0	439	34	genes	gene	NNS
cord-312486-rumqopg0	440	1	SARS	SARS	NNP
cord-312486-rumqopg0	440	2	-	-	HYPH
cord-312486-rumqopg0	440	3	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	440	4	receptor	receptor	NN
cord-312486-rumqopg0	440	5	ACE2	ACE2	NNP
cord-312486-rumqopg0	440	6	is	be	VBZ
cord-312486-rumqopg0	440	7	an	an	DT
cord-312486-rumqopg0	440	8	interferon	interferon	NN
cord-312486-rumqopg0	440	9	-	-	HYPH
cord-312486-rumqopg0	440	10	stimulated	stimulate	VBN
cord-312486-rumqopg0	440	11	gene	gene	NN
cord-312486-rumqopg0	440	12	in	in	IN
cord-312486-rumqopg0	440	13	human	human	JJ
cord-312486-rumqopg0	440	14	airway	airway	NN
cord-312486-rumqopg0	440	15	epithelial	epithelial	JJ
cord-312486-rumqopg0	440	16	cells	cell	NNS
cord-312486-rumqopg0	440	17	and	and	CC
cord-312486-rumqopg0	440	18	is	be	VBZ
cord-312486-rumqopg0	440	19	detected	detect	VBN
cord-312486-rumqopg0	440	20	in	in	IN
cord-312486-rumqopg0	440	21	specific	specific	JJ
cord-312486-rumqopg0	440	22	cell	cell	NN
cord-312486-rumqopg0	440	23	subsets	subset	NNS
cord-312486-rumqopg0	440	24	across	across	IN
cord-312486-rumqopg0	440	25	tissues	tissue	NNS
cord-312486-rumqopg0	440	26	Clinical	clinical	JJ
cord-312486-rumqopg0	440	27	characteristics	characteristic	NNS
cord-312486-rumqopg0	440	28	of	of	IN
cord-312486-rumqopg0	440	29	113	113	CD
cord-312486-rumqopg0	440	30	deceased	deceased	JJ
cord-312486-rumqopg0	440	31	patients	patient	NNS
cord-312486-rumqopg0	440	32	with	with	IN
cord-312486-rumqopg0	440	33	coronavirus	coronavirus	NN
cord-312486-rumqopg0	440	34	disease	disease	NN
cord-312486-rumqopg0	440	35	2019	2019	CD
cord-312486-rumqopg0	440	36	:	:	:
cord-312486-rumqopg0	441	1	Retrospective	retrospective	JJ
cord-312486-rumqopg0	441	2	study	study	NN
cord-312486-rumqopg0	441	3	Clinical	clinical	JJ
cord-312486-rumqopg0	441	4	predictors	predictor	NNS
cord-312486-rumqopg0	441	5	of	of	IN
cord-312486-rumqopg0	441	6	mortality	mortality	NN
cord-312486-rumqopg0	441	7	due	due	IN
cord-312486-rumqopg0	441	8	to	to	IN
cord-312486-rumqopg0	441	9	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	441	10	based	base	VBN
cord-312486-rumqopg0	441	11	on	on	IN
cord-312486-rumqopg0	441	12	an	an	DT
cord-312486-rumqopg0	441	13	analysis	analysis	NN
cord-312486-rumqopg0	441	14	of	of	IN
cord-312486-rumqopg0	441	15	data	datum	NNS
cord-312486-rumqopg0	441	16	of	of	IN
cord-312486-rumqopg0	441	17	150	150	CD
cord-312486-rumqopg0	441	18	patients	patient	NNS
cord-312486-rumqopg0	441	19	from	from	IN
cord-312486-rumqopg0	441	20	Wuhan	Wuhan	NNP
cord-312486-rumqopg0	441	21	,	,	,
cord-312486-rumqopg0	441	22	China	China	NNP
cord-312486-rumqopg0	441	23	Individual	individual	JJ
cord-312486-rumqopg0	441	24	variation	variation	NN
cord-312486-rumqopg0	441	25	of	of	IN
cord-312486-rumqopg0	441	26	the	the	DT
cord-312486-rumqopg0	441	27	SARS	SARS	NNP
cord-312486-rumqopg0	441	28	-	-	HYPH
cord-312486-rumqopg0	441	29	CoV2	CoV2	NNP
cord-312486-rumqopg0	441	30	Receptor	Receptor	NNP
cord-312486-rumqopg0	441	31	ACE2	ACE2	NNP
cord-312486-rumqopg0	441	32	gene	gene	NN
cord-312486-rumqopg0	441	33	expression	expression	NN
cord-312486-rumqopg0	441	34	and	and	CC
cord-312486-rumqopg0	441	35	regulation	regulation	NN
cord-312486-rumqopg0	441	36	Nasal	nasal	NN
cord-312486-rumqopg0	441	37	ACE2	ACE2	NNP
cord-312486-rumqopg0	441	38	Levels	Levels	NNPS
cord-312486-rumqopg0	441	39	and	and	CC
cord-312486-rumqopg0	441	40	COVID-19	covid-19	VB
cord-312486-rumqopg0	441	41	in	in	IN
cord-312486-rumqopg0	441	42	Children	Children	NNP
cord-312486-rumqopg0	441	43	Efficient	Efficient	NNP
cord-312486-rumqopg0	441	44	activation	activation	NN
cord-312486-rumqopg0	441	45	of	of	IN
cord-312486-rumqopg0	441	46	the	the	DT
cord-312486-rumqopg0	441	47	severe	severe	JJ
cord-312486-rumqopg0	441	48	acute	acute	JJ
cord-312486-rumqopg0	441	49	respiratory	respiratory	JJ
cord-312486-rumqopg0	441	50	syndrome	syndrome	NN
cord-312486-rumqopg0	441	51	coronavirus	coronavirus	NN
cord-312486-rumqopg0	441	52	spike	spike	NN
cord-312486-rumqopg0	441	53	protein	protein	NN
cord-312486-rumqopg0	441	54	by	by	IN
cord-312486-rumqopg0	441	55	the	the	DT
cord-312486-rumqopg0	441	56	transmembrane	transmembrane	NNP
cord-312486-rumqopg0	441	57	protease	protease	NN
cord-312486-rumqopg0	441	58	TMPRSS2	TMPRSS2	NNP
cord-312486-rumqopg0	441	59	Middle	Middle	NNP
cord-312486-rumqopg0	441	60	East	East	NNP
cord-312486-rumqopg0	441	61	respiratory	respiratory	JJ
cord-312486-rumqopg0	441	62	syndrome	syndrome	NN
cord-312486-rumqopg0	441	63	coronavirus	coronavirus	NN
cord-312486-rumqopg0	441	64	infection	infection	NN
cord-312486-rumqopg0	441	65	mediated	mediate	VBN
cord-312486-rumqopg0	441	66	by	by	IN
cord-312486-rumqopg0	441	67	the	the	DT
cord-312486-rumqopg0	441	68	transmembrane	transmembrane	NNP
cord-312486-rumqopg0	441	69	serine	serine	NN
cord-312486-rumqopg0	441	70	protease	protease	NN
cord-312486-rumqopg0	441	71	TMPRSS2	TMPRSS2	NNP
cord-312486-rumqopg0	441	72	TMPRSS2	TMPRSS2	NNP
cord-312486-rumqopg0	441	73	activates	activate	VBZ
cord-312486-rumqopg0	441	74	the	the	DT
cord-312486-rumqopg0	441	75	human	human	JJ
cord-312486-rumqopg0	441	76	coronavirus	coronavirus	NN
cord-312486-rumqopg0	441	77	229E	229e	CD
cord-312486-rumqopg0	441	78	for	for	IN
cord-312486-rumqopg0	441	79	cathepsin	cathepsin	NN
cord-312486-rumqopg0	441	80	-	-	HYPH
cord-312486-rumqopg0	441	81	independent	independent	JJ
cord-312486-rumqopg0	441	82	host	host	NN
cord-312486-rumqopg0	441	83	cell	cell	NN
cord-312486-rumqopg0	441	84	entry	entry	NN
cord-312486-rumqopg0	441	85	and	and	CC
cord-312486-rumqopg0	441	86	is	be	VBZ
cord-312486-rumqopg0	441	87	expressed	express	VBN
cord-312486-rumqopg0	441	88	in	in	IN
cord-312486-rumqopg0	441	89	viral	viral	JJ
cord-312486-rumqopg0	441	90	target	target	NN
cord-312486-rumqopg0	441	91	cells	cell	NNS
cord-312486-rumqopg0	441	92	in	in	IN
cord-312486-rumqopg0	441	93	the	the	DT
cord-312486-rumqopg0	441	94	respiratory	respiratory	JJ
cord-312486-rumqopg0	441	95	epithelium	epithelium	NN
cord-312486-rumqopg0	442	1	TMPRSS2	TMPRSS2	NNP
cord-312486-rumqopg0	442	2	contributes	contribute	VBZ
cord-312486-rumqopg0	442	3	to	to	IN
cord-312486-rumqopg0	442	4	virus	virus	NN
cord-312486-rumqopg0	442	5	spread	spread	VB
cord-312486-rumqopg0	442	6	and	and	CC
cord-312486-rumqopg0	442	7	immunopathology	immunopathology	NN
cord-312486-rumqopg0	442	8	in	in	IN
cord-312486-rumqopg0	442	9	the	the	DT
cord-312486-rumqopg0	442	10	airways	airway	NNS
cord-312486-rumqopg0	442	11	of	of	IN
cord-312486-rumqopg0	442	12	murine	murine	JJ
cord-312486-rumqopg0	442	13	models	model	NNS
cord-312486-rumqopg0	442	14	after	after	IN
cord-312486-rumqopg0	442	15	coronavirus	coronavirus	NN
cord-312486-rumqopg0	442	16	infection	infection	NN
cord-312486-rumqopg0	442	17	Proteolytic	Proteolytic	NNP
cord-312486-rumqopg0	442	18	activation	activation	NN
cord-312486-rumqopg0	442	19	of	of	IN
cord-312486-rumqopg0	442	20	influenza	influenza	NN
cord-312486-rumqopg0	442	21	viruses	virus	NNS
cord-312486-rumqopg0	442	22	by	by	IN
cord-312486-rumqopg0	442	23	serine	serine	NN
cord-312486-rumqopg0	442	24	proteases	protease	NNS
cord-312486-rumqopg0	442	25	TMPRSS2	TMPRSS2	NNP
cord-312486-rumqopg0	442	26	and	and	CC
cord-312486-rumqopg0	442	27	HAT	HAT	NNP
cord-312486-rumqopg0	442	28	from	from	IN
cord-312486-rumqopg0	442	29	human	human	JJ
cord-312486-rumqopg0	442	30	airway	airway	NN
cord-312486-rumqopg0	442	31	epithelium	epithelium	NN
cord-312486-rumqopg0	442	32	Identification	Identification	NNP
cord-312486-rumqopg0	442	33	of	of	IN
cord-312486-rumqopg0	442	34	TMPRSS2	TMPRSS2	NNP
cord-312486-rumqopg0	442	35	as	as	IN
cord-312486-rumqopg0	442	36	a	a	DT
cord-312486-rumqopg0	442	37	susceptibility	susceptibility	NN
cord-312486-rumqopg0	442	38	gene	gene	NN
cord-312486-rumqopg0	442	39	for	for	IN
cord-312486-rumqopg0	442	40	severe	severe	JJ
cord-312486-rumqopg0	442	41	2009	2009	CD
cord-312486-rumqopg0	442	42	pandemic	pandemic	NN
cord-312486-rumqopg0	442	43	A(H1N1	A(H1N1	NNP
cord-312486-rumqopg0	442	44	)	)	-RRB-
cord-312486-rumqopg0	442	45	influenza	influenza	NN
cord-312486-rumqopg0	442	46	and	and	CC
cord-312486-rumqopg0	442	47	A(H7N9	A(H7N9	NNP
cord-312486-rumqopg0	442	48	)	)	-RRB-
cord-312486-rumqopg0	443	1	influenza	influenza	NNP
cord-312486-rumqopg0	443	2	ACE2	ACE2	NNP
cord-312486-rumqopg0	443	3	and	and	CC
cord-312486-rumqopg0	443	4	TMPRSS2	TMPRSS2	NNP
cord-312486-rumqopg0	443	5	variants	variant	NNS
cord-312486-rumqopg0	443	6	and	and	CC
cord-312486-rumqopg0	443	7	expression	expression	NN
cord-312486-rumqopg0	443	8	as	as	IN
cord-312486-rumqopg0	443	9	candidates	candidate	NNS
cord-312486-rumqopg0	443	10	to	to	IN
cord-312486-rumqopg0	443	11	sex	sex	NN
cord-312486-rumqopg0	443	12	and	and	CC
cord-312486-rumqopg0	443	13	country	country	NN
cord-312486-rumqopg0	443	14	differences	difference	NNS
cord-312486-rumqopg0	443	15	in	in	IN
cord-312486-rumqopg0	443	16	COVID-19	covid-19	JJ
cord-312486-rumqopg0	443	17	severity	severity	NN
cord-312486-rumqopg0	443	18	in	in	IN
cord-312486-rumqopg0	443	19	Italy	Italy	NNP
cord-312486-rumqopg0	444	1	A	a	DT
cord-312486-rumqopg0	444	2	functional	functional	JJ
cord-312486-rumqopg0	444	3	genomic	genomic	JJ
cord-312486-rumqopg0	444	4	approach	approach	NN
cord-312486-rumqopg0	444	5	to	to	TO
cord-312486-rumqopg0	444	6	understand	understand	VB
cord-312486-rumqopg0	444	7	variation	variation	NN
cord-312486-rumqopg0	444	8	in	in	IN
cord-312486-rumqopg0	444	9	cytokine	cytokine	NN
cord-312486-rumqopg0	444	10	production	production	NN
cord-312486-rumqopg0	444	11	Linking	link	VBG
cord-312486-rumqopg0	444	12	the	the	DT
cord-312486-rumqopg0	444	13	human	human	JJ
cord-312486-rumqopg0	444	14	gut	gut	NN
cord-312486-rumqopg0	444	15	microbiome	microbiome	NN
cord-312486-rumqopg0	444	16	to	to	IN
cord-312486-rumqopg0	444	17	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	444	18	cytokine	cytokine	NN
cord-312486-rumqopg0	444	19	production	production	NN
cord-312486-rumqopg0	444	20	capacity	capacity	NN
cord-312486-rumqopg0	444	21	Tumor	tumor	NN
cord-312486-rumqopg0	444	22	necrosis	necrosis	NN
cord-312486-rumqopg0	444	23	factor	factor	NN
cord-312486-rumqopg0	444	24	-	-	HYPH
cord-312486-rumqopg0	444	25	alpha	alpha	NN
cord-312486-rumqopg0	444	26	in	in	IN
cord-312486-rumqopg0	444	27	murine	murine	JJ
cord-312486-rumqopg0	444	28	autoimmune	autoimmune	NN
cord-312486-rumqopg0	445	1	'	'	``
cord-312486-rumqopg0	445	2	lupus	lupus	NN
cord-312486-rumqopg0	445	3	'	'	''
cord-312486-rumqopg0	445	4	nephritis	nephritis	NN
cord-312486-rumqopg0	445	5	Heritable	heritable	JJ
cord-312486-rumqopg0	445	6	major	major	JJ
cord-312486-rumqopg0	445	7	histocompatibility	histocompatibility	NN
cord-312486-rumqopg0	445	8	complex	complex	JJ
cord-312486-rumqopg0	445	9	class	class	NN
cord-312486-rumqopg0	445	10	II	ii	NN
cord-312486-rumqopg0	445	11	-	-	HYPH
cord-312486-rumqopg0	445	12	associated	associate	VBN
cord-312486-rumqopg0	445	13	differences	difference	NNS
cord-312486-rumqopg0	445	14	in	in	IN
cord-312486-rumqopg0	445	15	production	production	NN
cord-312486-rumqopg0	445	16	of	of	IN
cord-312486-rumqopg0	445	17	tumor	tumor	NN
cord-312486-rumqopg0	445	18	necrosis	necrosis	NN
cord-312486-rumqopg0	445	19	factor	factor	NN
cord-312486-rumqopg0	445	20	alpha	alpha	NN
cord-312486-rumqopg0	445	21	:	:	:
cord-312486-rumqopg0	445	22	relevance	relevance	NN
cord-312486-rumqopg0	445	23	to	to	IN
cord-312486-rumqopg0	445	24	genetic	genetic	JJ
cord-312486-rumqopg0	445	25	predisposition	predisposition	NN
cord-312486-rumqopg0	445	26	to	to	IN
cord-312486-rumqopg0	445	27	systemic	systemic	JJ
cord-312486-rumqopg0	445	28	lupus	lupus	NN
cord-312486-rumqopg0	446	1	erythematosus	erythematosus	NN
cord-312486-rumqopg0	447	1	Racial	racial	JJ
cord-312486-rumqopg0	447	2	disparity	disparity	NN
cord-312486-rumqopg0	447	3	in	in	IN
cord-312486-rumqopg0	447	4	Covid-19	covid-19	NN
cord-312486-rumqopg0	447	5	mortality	mortality	NN
cord-312486-rumqopg0	447	6	rates	rate	NNS
cord-312486-rumqopg0	448	1	-A	-A	:
cord-312486-rumqopg0	448	2	plausible	plausible	JJ
cord-312486-rumqopg0	448	3	explanation	explanation	NN
cord-312486-rumqopg0	449	1	Genomewide	Genomewide	NNP
cord-312486-rumqopg0	449	2	association	association	NN
cord-312486-rumqopg0	449	3	study	study	NN
cord-312486-rumqopg0	449	4	of	of	IN
cord-312486-rumqopg0	449	5	severe	severe	JJ
cord-312486-rumqopg0	449	6	Covid-19	covid-19	NN
cord-312486-rumqopg0	449	7	with	with	IN
cord-312486-rumqopg0	449	8	respiratory	respiratory	JJ
cord-312486-rumqopg0	449	9	failure	failure	NN
cord-312486-rumqopg0	449	10	Human	human	JJ
cord-312486-rumqopg0	449	11	intestine	intestine	NN
cord-312486-rumqopg0	449	12	luminal	luminal	JJ
cord-312486-rumqopg0	449	13	ACE2	ACE2	NNP
cord-312486-rumqopg0	449	14	and	and	CC
cord-312486-rumqopg0	449	15	amino	amino	NN
cord-312486-rumqopg0	449	16	acid	acid	NN
cord-312486-rumqopg0	449	17	transporter	transporter	NN
cord-312486-rumqopg0	449	18	expression	expression	NN
cord-312486-rumqopg0	449	19	increased	increase	VBN
cord-312486-rumqopg0	449	20	by	by	IN
cord-312486-rumqopg0	449	21	ACEinhibitors	aceinhibitor	NNS
cord-312486-rumqopg0	450	1	The	the	DT
cord-312486-rumqopg0	450	2	tryptophan	tryptophan	NN
cord-312486-rumqopg0	450	3	catabolite	catabolite	JJ
cord-312486-rumqopg0	450	4	picolinic	picolinic	NN
cord-312486-rumqopg0	450	5	acid	acid	NN
cord-312486-rumqopg0	450	6	selectively	selectively	RB
cord-312486-rumqopg0	450	7	induces	induce	VBZ
cord-312486-rumqopg0	450	8	the	the	DT
cord-312486-rumqopg0	450	9	chemokines	chemokine	NNS
cord-312486-rumqopg0	450	10	macrophage	macrophage	NN
cord-312486-rumqopg0	450	11	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	450	12	protein-1	protein-1	NNP
cord-312486-rumqopg0	450	13	alpha	alpha	NN
cord-312486-rumqopg0	451	1	and	and	CC
cord-312486-rumqopg0	451	2	-1	-1	NN
cord-312486-rumqopg0	451	3	beta	beta	NN
cord-312486-rumqopg0	451	4	in	in	IN
cord-312486-rumqopg0	451	5	macrophages	macrophage	NNS
cord-312486-rumqopg0	451	6	Influence	influence	NN
cord-312486-rumqopg0	451	7	of	of	IN
cord-312486-rumqopg0	451	8	glutamine	glutamine	NN
cord-312486-rumqopg0	451	9	on	on	IN
cord-312486-rumqopg0	451	10	cytokine	cytokine	NN
cord-312486-rumqopg0	451	11	production	production	NN
cord-312486-rumqopg0	451	12	by	by	IN
cord-312486-rumqopg0	451	13	human	human	JJ
cord-312486-rumqopg0	451	14	gut	gut	NN
cord-312486-rumqopg0	451	15	in	in	IN
cord-312486-rumqopg0	451	16	vitro	vitro	FW
cord-312486-rumqopg0	451	17	Genome	Genome	NNP
cord-312486-rumqopg0	451	18	-	-	HYPH
cord-312486-rumqopg0	451	19	wide	wide	JJ
cord-312486-rumqopg0	451	20	association	association	NN
cord-312486-rumqopg0	451	21	study	study	NN
cord-312486-rumqopg0	451	22	of	of	IN
cord-312486-rumqopg0	451	23	spontaneous	spontaneous	JJ
cord-312486-rumqopg0	451	24	resolution	resolution	NN
cord-312486-rumqopg0	451	25	of	of	IN
cord-312486-rumqopg0	451	26	hepatitis	hepatitis	NN
cord-312486-rumqopg0	451	27	C	C	NNP
cord-312486-rumqopg0	451	28	virus	virus	NN
cord-312486-rumqopg0	451	29	infection	infection	NN
cord-312486-rumqopg0	451	30	:	:	:
cord-312486-rumqopg0	451	31	data	datum	NNS
cord-312486-rumqopg0	451	32	from	from	IN
cord-312486-rumqopg0	451	33	multiple	multiple	JJ
cord-312486-rumqopg0	451	34	cohorts	cohort	NNS
cord-312486-rumqopg0	452	1	A	a	DT
cord-312486-rumqopg0	452	2	whole	whole	JJ
cord-312486-rumqopg0	452	3	-	-	HYPH
cord-312486-rumqopg0	452	4	genome	genome	NN
cord-312486-rumqopg0	452	5	association	association	NN
cord-312486-rumqopg0	452	6	study	study	NN
cord-312486-rumqopg0	452	7	of	of	IN
cord-312486-rumqopg0	452	8	major	major	JJ
cord-312486-rumqopg0	452	9	determinants	determinant	NNS
cord-312486-rumqopg0	452	10	for	for	IN
cord-312486-rumqopg0	452	11	host	host	NN
cord-312486-rumqopg0	452	12	control	control	NN
cord-312486-rumqopg0	452	13	of	of	IN
cord-312486-rumqopg0	453	1	HIV-1	HIV-1	NNP
cord-312486-rumqopg0	453	2	IFN	IFN	NNP
cord-312486-rumqopg0	453	3	-	-	HYPH
cord-312486-rumqopg0	453	4	I	-PRON-	PRP
cord-312486-rumqopg0	453	5	response	response	NN
cord-312486-rumqopg0	453	6	timing	timing	NN
cord-312486-rumqopg0	453	7	relative	relative	JJ
cord-312486-rumqopg0	453	8	to	to	IN
cord-312486-rumqopg0	453	9	virus	virus	NN
cord-312486-rumqopg0	453	10	replication	replication	NN
cord-312486-rumqopg0	453	11	determines	determine	VBZ
cord-312486-rumqopg0	453	12	MERS	MERS	NNP
cord-312486-rumqopg0	453	13	coronavirus	coronavirus	NN
cord-312486-rumqopg0	453	14	infection	infection	NN
cord-312486-rumqopg0	453	15	outcomes	outcome	NNS
cord-312486-rumqopg0	453	16	LY6E	LY6E	NNP
cord-312486-rumqopg0	453	17	impairs	impair	VBZ
cord-312486-rumqopg0	453	18	coronavirus	coronavirus	NN
cord-312486-rumqopg0	453	19	fusion	fusion	NN
cord-312486-rumqopg0	453	20	and	and	CC
cord-312486-rumqopg0	453	21	confers	confer	VBZ
cord-312486-rumqopg0	453	22	immune	immune	JJ
cord-312486-rumqopg0	453	23	control	control	NN
cord-312486-rumqopg0	453	24	of	of	IN
cord-312486-rumqopg0	453	25	viral	viral	JJ
cord-312486-rumqopg0	453	26	disease	disease	NN
cord-312486-rumqopg0	454	1	Distinct	distinct	JJ
cord-312486-rumqopg0	454	2	patterns	pattern	NNS
cord-312486-rumqopg0	454	3	of	of	IN
cord-312486-rumqopg0	454	4	IFITM	ifitm	NN
cord-312486-rumqopg0	454	5	-	-	HYPH
cord-312486-rumqopg0	454	6	mediated	mediate	VBN
cord-312486-rumqopg0	454	7	restriction	restriction	NN
cord-312486-rumqopg0	454	8	of	of	IN
cord-312486-rumqopg0	454	9	filoviruses	filovirus	NNS
cord-312486-rumqopg0	454	10	,	,	,
cord-312486-rumqopg0	454	11	SARS	SARS	NNP
cord-312486-rumqopg0	454	12	coronavirus	coronavirus	NN
cord-312486-rumqopg0	454	13	,	,	,
cord-312486-rumqopg0	454	14	and	and	CC
cord-312486-rumqopg0	454	15	influenza	influenza	NN
cord-312486-rumqopg0	454	16	A	a	DT
cord-312486-rumqopg0	454	17	virus	virus	NN
cord-312486-rumqopg0	455	1	SARS	SARS	NNP
cord-312486-rumqopg0	455	2	-	-	HYPH
cord-312486-rumqopg0	455	3	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	456	1	ORF3b	ORF3b	NNP
cord-312486-rumqopg0	456	2	is	be	VBZ
cord-312486-rumqopg0	456	3	a	a	DT
cord-312486-rumqopg0	456	4	potent	potent	JJ
cord-312486-rumqopg0	456	5	interferon	interferon	NN
cord-312486-rumqopg0	456	6	antagonist	antagonist	NN
cord-312486-rumqopg0	456	7	whose	whose	WP$
cord-312486-rumqopg0	456	8	activity	activity	NN
cord-312486-rumqopg0	456	9	is	be	VBZ
cord-312486-rumqopg0	456	10	further	far	RBR
cord-312486-rumqopg0	456	11	increased	increase	VBN
cord-312486-rumqopg0	456	12	by	by	IN
cord-312486-rumqopg0	456	13	a	a	DT
cord-312486-rumqopg0	456	14	naturally	naturally	RB
cord-312486-rumqopg0	456	15	occurring	occur	VBG
cord-312486-rumqopg0	456	16	elongation	elongation	NN
cord-312486-rumqopg0	456	17	variant	variant	NN
cord-312486-rumqopg0	456	18	Impaired	impair	VBN
cord-312486-rumqopg0	456	19	type	type	NN
cord-312486-rumqopg0	457	1	I	-PRON-	PRP
cord-312486-rumqopg0	457	2	interferon	interferon	VBD
cord-312486-rumqopg0	457	3	activity	activity	NN
cord-312486-rumqopg0	457	4	and	and	CC
cord-312486-rumqopg0	457	5	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	457	6	responses	response	NNS
cord-312486-rumqopg0	457	7	in	in	IN
cord-312486-rumqopg0	457	8	severe	severe	JJ
cord-312486-rumqopg0	457	9	COVID-19	covid-19	JJ
cord-312486-rumqopg0	457	10	patients	patient	NNS
cord-312486-rumqopg0	457	11	Imbalanced	imbalanced	JJ
cord-312486-rumqopg0	457	12	host	host	NN
cord-312486-rumqopg0	457	13	response	response	NN
cord-312486-rumqopg0	457	14	to	to	IN
cord-312486-rumqopg0	457	15	SARS	SARS	NNP
cord-312486-rumqopg0	457	16	-	-	HYPH
cord-312486-rumqopg0	457	17	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	457	18	drives	drive	VBZ
cord-312486-rumqopg0	457	19	development	development	NN
cord-312486-rumqopg0	457	20	of	of	IN
cord-312486-rumqopg0	457	21	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	457	22	Severe	severe	JJ
cord-312486-rumqopg0	457	23	acute	acute	JJ
cord-312486-rumqopg0	457	24	respiratory	respiratory	JJ
cord-312486-rumqopg0	457	25	syndrome	syndrome	NN
cord-312486-rumqopg0	457	26	coronavirus	coronavirus	NN
cord-312486-rumqopg0	457	27	viroporin	viroporin	NNP
cord-312486-rumqopg0	457	28	3a	3a	NNP
cord-312486-rumqopg0	457	29	activates	activate	VBZ
cord-312486-rumqopg0	457	30	the	the	DT
cord-312486-rumqopg0	457	31	NLRP3	NLRP3	NNP
cord-312486-rumqopg0	457	32	inflammasome	inflammasome	NNP
cord-312486-rumqopg0	457	33	Virus	Virus	NNP
cord-312486-rumqopg0	457	34	-	-	HYPH
cord-312486-rumqopg0	457	35	host	host	NN
cord-312486-rumqopg0	457	36	interactome	interactome	NNP
cord-312486-rumqopg0	457	37	and	and	CC
cord-312486-rumqopg0	457	38	proteomic	proteomic	JJ
cord-312486-rumqopg0	457	39	survey	survey	NN
cord-312486-rumqopg0	457	40	of	of	IN
cord-312486-rumqopg0	457	41	PBMCs	PBMCs	NNPS
cord-312486-rumqopg0	457	42	from	from	IN
cord-312486-rumqopg0	457	43	COVID-19	covid-19	CD
cord-312486-rumqopg0	457	44	patients	patient	NNS
cord-312486-rumqopg0	457	45	reveal	reveal	VBP
cord-312486-rumqopg0	457	46	potential	potential	JJ
cord-312486-rumqopg0	457	47	virulence	virulence	NN
cord-312486-rumqopg0	457	48	factors	factor	NNS
cord-312486-rumqopg0	457	49	influencing	influence	VBG
cord-312486-rumqopg0	457	50	SARS	SARS	NNP
cord-312486-rumqopg0	457	51	-	-	HYPH
cord-312486-rumqopg0	457	52	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	457	53	pathogenesis	pathogenesis	NN
cord-312486-rumqopg0	457	54	Immunology	Immunology	NNP
cord-312486-rumqopg0	457	55	of	of	IN
cord-312486-rumqopg0	457	56	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	457	57	:	:	:
cord-312486-rumqopg0	457	58	current	current	JJ
cord-312486-rumqopg0	457	59	state	state	NN
cord-312486-rumqopg0	457	60	of	of	IN
cord-312486-rumqopg0	457	61	the	the	DT
cord-312486-rumqopg0	457	62	science	science	NN
cord-312486-rumqopg0	457	63	Clinical	clinical	JJ
cord-312486-rumqopg0	457	64	progression	progression	NN
cord-312486-rumqopg0	457	65	and	and	CC
cord-312486-rumqopg0	457	66	viral	viral	JJ
cord-312486-rumqopg0	457	67	load	load	NN
cord-312486-rumqopg0	457	68	in	in	IN
cord-312486-rumqopg0	457	69	a	a	DT
cord-312486-rumqopg0	457	70	community	community	NN
cord-312486-rumqopg0	457	71	outbreak	outbreak	NN
cord-312486-rumqopg0	457	72	of	of	IN
cord-312486-rumqopg0	457	73	coronavirus	coronavirus	NN
cord-312486-rumqopg0	457	74	-	-	HYPH
cord-312486-rumqopg0	457	75	associated	associate	VBN
cord-312486-rumqopg0	457	76	SARS	SARS	NNP
cord-312486-rumqopg0	457	77	pneumonia	pneumonia	NN
cord-312486-rumqopg0	457	78	:	:	:
cord-312486-rumqopg0	457	79	a	a	DT
cord-312486-rumqopg0	457	80	prospective	prospective	JJ
cord-312486-rumqopg0	457	81	study	study	NN
cord-312486-rumqopg0	457	82	Temporal	temporal	JJ
cord-312486-rumqopg0	457	83	relationship	relationship	NN
cord-312486-rumqopg0	457	84	of	of	IN
cord-312486-rumqopg0	457	85	viral	viral	JJ
cord-312486-rumqopg0	457	86	load	load	NN
cord-312486-rumqopg0	457	87	,	,	,
cord-312486-rumqopg0	457	88	ribavirin	ribavirin	RB
cord-312486-rumqopg0	457	89	,	,	,
cord-312486-rumqopg0	457	90	interleukin	interleukin	FW
cord-312486-rumqopg0	457	91	(	(	-LRB-
cord-312486-rumqopg0	457	92	IL)-6	IL)-6	NNP
cord-312486-rumqopg0	457	93	,	,	,
cord-312486-rumqopg0	457	94	IL-8	IL-8	NNP
cord-312486-rumqopg0	457	95	,	,	,
cord-312486-rumqopg0	457	96	and	and	CC
cord-312486-rumqopg0	457	97	clinical	clinical	JJ
cord-312486-rumqopg0	457	98	progression	progression	NN
cord-312486-rumqopg0	457	99	in	in	IN
cord-312486-rumqopg0	457	100	patients	patient	NNS
cord-312486-rumqopg0	457	101	with	with	IN
cord-312486-rumqopg0	457	102	severe	severe	JJ
cord-312486-rumqopg0	457	103	acute	acute	JJ
cord-312486-rumqopg0	457	104	respiratory	respiratory	JJ
cord-312486-rumqopg0	457	105	syndrome	syndrome	NN
cord-312486-rumqopg0	458	1	Presenting	present	VBG
cord-312486-rumqopg0	458	2	characteristics	characteristic	NNS
cord-312486-rumqopg0	458	3	,	,	,
cord-312486-rumqopg0	458	4	comorbidities	comorbiditie	NNS
cord-312486-rumqopg0	458	5	,	,	,
cord-312486-rumqopg0	458	6	and	and	CC
cord-312486-rumqopg0	458	7	outcomes	outcome	NNS
cord-312486-rumqopg0	458	8	among	among	IN
cord-312486-rumqopg0	458	9	5700	5700	CD
cord-312486-rumqopg0	458	10	patients	patient	NNS
cord-312486-rumqopg0	458	11	hospitalized	hospitalize	VBN
cord-312486-rumqopg0	458	12	with	with	IN
cord-312486-rumqopg0	458	13	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	458	14	in	in	IN
cord-312486-rumqopg0	458	15	the	the	DT
cord-312486-rumqopg0	458	16	New	New	NNP
cord-312486-rumqopg0	458	17	York	York	NNP
cord-312486-rumqopg0	458	18	City	City	NNP
cord-312486-rumqopg0	458	19	area	area	NN
cord-312486-rumqopg0	458	20	Host	host	NN
cord-312486-rumqopg0	458	21	and	and	CC
cord-312486-rumqopg0	458	22	environmental	environmental	JJ
cord-312486-rumqopg0	458	23	factors	factor	NNS
cord-312486-rumqopg0	458	24	influencing	influence	VBG
cord-312486-rumqopg0	458	25	individual	individual	JJ
cord-312486-rumqopg0	458	26	human	human	JJ
cord-312486-rumqopg0	458	27	cytokine	cytokine	NN
cord-312486-rumqopg0	458	28	responses	response	NNS
cord-312486-rumqopg0	458	29	COVID-19	covid-19	VBP
cord-312486-rumqopg0	458	30	:	:	:
cord-312486-rumqopg0	458	31	consider	consider	VB
cord-312486-rumqopg0	458	32	cytokine	cytokine	JJ
cord-312486-rumqopg0	458	33	storm	storm	NN
cord-312486-rumqopg0	458	34	syndromes	syndrome	NNS
cord-312486-rumqopg0	458	35	and	and	CC
cord-312486-rumqopg0	458	36	immunosuppression	immunosuppression	NN
cord-312486-rumqopg0	459	1	A	a	DT
cord-312486-rumqopg0	459	2	single	single	JJ
cord-312486-rumqopg0	459	3	-	-	HYPH
cord-312486-rumqopg0	459	4	cell	cell	NN
cord-312486-rumqopg0	459	5	atlas	atlas	NN
cord-312486-rumqopg0	459	6	of	of	IN
cord-312486-rumqopg0	459	7	the	the	DT
cord-312486-rumqopg0	459	8	peripheral	peripheral	JJ
cord-312486-rumqopg0	459	9	immune	immune	JJ
cord-312486-rumqopg0	459	10	response	response	NN
cord-312486-rumqopg0	459	11	in	in	IN
cord-312486-rumqopg0	459	12	patients	patient	NNS
cord-312486-rumqopg0	459	13	with	with	IN
cord-312486-rumqopg0	459	14	severe	severe	JJ
cord-312486-rumqopg0	459	15	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	459	16	Inhibition	Inhibition	NNP
cord-312486-rumqopg0	459	17	of	of	IN
cord-312486-rumqopg0	459	18	natural	natural	JJ
cord-312486-rumqopg0	459	19	killer	killer	NN
cord-312486-rumqopg0	459	20	cell	cell	NN
cord-312486-rumqopg0	459	21	cytotoxicity	cytotoxicity	NN
cord-312486-rumqopg0	459	22	by	by	IN
cord-312486-rumqopg0	459	23	interleukin-6	interleukin-6	NNP
cord-312486-rumqopg0	459	24	:	:	:
cord-312486-rumqopg0	459	25	implications	implication	NNS
cord-312486-rumqopg0	459	26	for	for	IN
cord-312486-rumqopg0	459	27	the	the	DT
cord-312486-rumqopg0	459	28	pathogenesis	pathogenesis	NN
cord-312486-rumqopg0	459	29	of	of	IN
cord-312486-rumqopg0	459	30	macrophage	macrophage	NN
cord-312486-rumqopg0	459	31	activation	activation	NN
cord-312486-rumqopg0	459	32	syndrome	syndrome	NN
cord-312486-rumqopg0	459	33	Neutrophil	Neutrophil	NNP
cord-312486-rumqopg0	459	34	-	-	HYPH
cord-312486-rumqopg0	459	35	to	to	IN
cord-312486-rumqopg0	459	36	-	-	HYPH
cord-312486-rumqopg0	459	37	lymphocyte	lymphocyte	NN
cord-312486-rumqopg0	459	38	ratio	ratio	NN
cord-312486-rumqopg0	459	39	predicts	predict	VBZ
cord-312486-rumqopg0	459	40	critical	critical	JJ
cord-312486-rumqopg0	459	41	illness	illness	NN
cord-312486-rumqopg0	459	42	patients	patient	NNS
cord-312486-rumqopg0	459	43	with	with	IN
cord-312486-rumqopg0	459	44	2019	2019	CD
cord-312486-rumqopg0	459	45	coronavirus	coronavirus	NN
cord-312486-rumqopg0	459	46	disease	disease	NN
cord-312486-rumqopg0	459	47	in	in	IN
cord-312486-rumqopg0	459	48	the	the	DT
cord-312486-rumqopg0	459	49	early	early	JJ
cord-312486-rumqopg0	459	50	stage	stage	NN
cord-312486-rumqopg0	459	51	Dysregulation	Dysregulation	NNP
cord-312486-rumqopg0	459	52	of	of	IN
cord-312486-rumqopg0	459	53	immune	immune	JJ
cord-312486-rumqopg0	459	54	response	response	NN
cord-312486-rumqopg0	459	55	in	in	IN
cord-312486-rumqopg0	459	56	patients	patient	NNS
cord-312486-rumqopg0	459	57	with	with	IN
cord-312486-rumqopg0	459	58	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	459	59	in	in	IN
cord-312486-rumqopg0	459	60	Wuhan	Wuhan	NNP
cord-312486-rumqopg0	459	61	,	,	,
cord-312486-rumqopg0	459	62	China	China	NNP
cord-312486-rumqopg0	459	63	Heightened	heighten	VBD
cord-312486-rumqopg0	459	64	innate	innate	JJ
cord-312486-rumqopg0	459	65	immune	immune	JJ
cord-312486-rumqopg0	459	66	responses	response	NNS
cord-312486-rumqopg0	459	67	in	in	IN
cord-312486-rumqopg0	459	68	the	the	DT
cord-312486-rumqopg0	459	69	respiratory	respiratory	JJ
cord-312486-rumqopg0	459	70	tract	tract	NN
cord-312486-rumqopg0	459	71	of	of	IN
cord-312486-rumqopg0	459	72	COVID-19	covid-19	CD
cord-312486-rumqopg0	459	73	patients	patient	NNS
cord-312486-rumqopg0	459	74	Clinical	clinical	JJ
cord-312486-rumqopg0	459	75	features	feature	NNS
cord-312486-rumqopg0	459	76	of	of	IN
cord-312486-rumqopg0	459	77	patients	patient	NNS
cord-312486-rumqopg0	459	78	infected	infect	VBN
cord-312486-rumqopg0	459	79	with	with	IN
cord-312486-rumqopg0	459	80	2019	2019	CD
cord-312486-rumqopg0	459	81	novel	novel	JJ
cord-312486-rumqopg0	459	82	coronavirus	coronavirus	NN
cord-312486-rumqopg0	459	83	in	in	IN
cord-312486-rumqopg0	459	84	Transcriptomic	Transcriptomic	NNP
cord-312486-rumqopg0	459	85	characteristics	characteristic	NNS
cord-312486-rumqopg0	459	86	of	of	IN
cord-312486-rumqopg0	459	87	bronchoalveolar	bronchoalveolar	NNP
cord-312486-rumqopg0	459	88	lavage	lavage	NN
cord-312486-rumqopg0	459	89	fluid	fluid	NN
cord-312486-rumqopg0	459	90	and	and	CC
cord-312486-rumqopg0	459	91	peripheral	peripheral	JJ
cord-312486-rumqopg0	459	92	blood	blood	NN
cord-312486-rumqopg0	459	93	mononuclear	mononuclear	NN
cord-312486-rumqopg0	459	94	cells	cell	NNS
cord-312486-rumqopg0	459	95	in	in	IN
cord-312486-rumqopg0	459	96	COVID-19	covid-19	CD
cord-312486-rumqopg0	459	97	patients	patient	NNS
cord-312486-rumqopg0	460	1	Dysregulated	Dysregulated	NNP
cord-312486-rumqopg0	460	2	type	type	NN
cord-312486-rumqopg0	461	1	I	-PRON-	PRP
cord-312486-rumqopg0	461	2	interferon	interferon	VBD
cord-312486-rumqopg0	461	3	and	and	CC
cord-312486-rumqopg0	461	4	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	461	5	monocyte	monocyte	JJ
cord-312486-rumqopg0	461	6	-	-	HYPH
cord-312486-rumqopg0	461	7	macrophage	macrophage	NN
cord-312486-rumqopg0	461	8	responses	response	NNS
cord-312486-rumqopg0	461	9	cause	cause	VBP
cord-312486-rumqopg0	461	10	lethal	lethal	JJ
cord-312486-rumqopg0	461	11	pneumonia	pneumonia	NN
cord-312486-rumqopg0	461	12	in	in	IN
cord-312486-rumqopg0	461	13	SARS	SARS	NNP
cord-312486-rumqopg0	461	14	-	-	HYPH
cord-312486-rumqopg0	461	15	CoV	CoV	NNP
cord-312486-rumqopg0	461	16	-	-	HYPH
cord-312486-rumqopg0	461	17	infected	infect	VBN
cord-312486-rumqopg0	461	18	mice	mouse	NNS
cord-312486-rumqopg0	461	19	Complement	complement	VBP
cord-312486-rumqopg0	461	20	evasion	evasion	NN
cord-312486-rumqopg0	461	21	strategies	strategy	NNS
cord-312486-rumqopg0	461	22	of	of	IN
cord-312486-rumqopg0	461	23	viruses	virus	NNS
cord-312486-rumqopg0	461	24	:	:	:
cord-312486-rumqopg0	462	1	an	an	DT
cord-312486-rumqopg0	462	2	overview	overview	NN
cord-312486-rumqopg0	462	3	The	the	DT
cord-312486-rumqopg0	462	4	Complement	Complement	NNP
cord-312486-rumqopg0	462	5	System	System	NNP
cord-312486-rumqopg0	462	6	in	in	IN
cord-312486-rumqopg0	462	7	COVID-19	covid-19	NN
cord-312486-rumqopg0	462	8	:	:	:
cord-312486-rumqopg0	462	9	Friend	friend	NN
cord-312486-rumqopg0	462	10	and	and	CC
cord-312486-rumqopg0	462	11	Foe	Foe	NNP
cord-312486-rumqopg0	462	12	?	?	.
cord-312486-rumqopg0	463	1	Complement	complement	JJ
cord-312486-rumqopg0	463	2	activation	activation	NN
cord-312486-rumqopg0	463	3	contributes	contribute	VBZ
cord-312486-rumqopg0	463	4	to	to	IN
cord-312486-rumqopg0	463	5	severe	severe	JJ
cord-312486-rumqopg0	463	6	acute	acute	JJ
cord-312486-rumqopg0	463	7	respiratory	respiratory	JJ
cord-312486-rumqopg0	463	8	syndrome	syndrome	NN
cord-312486-rumqopg0	463	9	coronavirus	coronavirus	NN
cord-312486-rumqopg0	463	10	pathogenesis	pathogenesis	NN
cord-312486-rumqopg0	464	1	Highly	highly	RB
cord-312486-rumqopg0	464	2	pathogenic	pathogenic	JJ
cord-312486-rumqopg0	464	3	coronavirus	coronavirus	NN
cord-312486-rumqopg0	464	4	N	n	CD
cord-312486-rumqopg0	464	5	protein	protein	NN
cord-312486-rumqopg0	464	6	aggravates	aggravate	VBZ
cord-312486-rumqopg0	464	7	lung	lung	NN
cord-312486-rumqopg0	464	8	injury	injury	NN
cord-312486-rumqopg0	464	9	by	by	IN
cord-312486-rumqopg0	464	10	MASP-2-mediated	masp-2-mediate	VBN
cord-312486-rumqopg0	464	11	complement	complement	VB
cord-312486-rumqopg0	464	12	over	over	IN
cord-312486-rumqopg0	464	13	-	-	HYPH
cord-312486-rumqopg0	464	14	activation	activation	NN
cord-312486-rumqopg0	464	15	.	.	.
cord-312486-rumqopg0	465	1	medRxiv	medRxiv	NNP
cord-312486-rumqopg0	465	2	Expression	expression	NN
cord-312486-rumqopg0	465	3	of	of	IN
cord-312486-rumqopg0	465	4	ABO	ABO	NNP
cord-312486-rumqopg0	465	5	or	or	CC
cord-312486-rumqopg0	465	6	related	relate	VBN
cord-312486-rumqopg0	465	7	antigenic	antigenic	JJ
cord-312486-rumqopg0	465	8	carbohydrates	carbohydrate	NNS
cord-312486-rumqopg0	465	9	on	on	IN
cord-312486-rumqopg0	465	10	viral	viral	JJ
cord-312486-rumqopg0	465	11	envelopes	envelope	NNS
cord-312486-rumqopg0	465	12	leads	lead	VBZ
cord-312486-rumqopg0	465	13	to	to	IN
cord-312486-rumqopg0	465	14	neutralization	neutralization	NN
cord-312486-rumqopg0	465	15	in	in	IN
cord-312486-rumqopg0	465	16	the	the	DT
cord-312486-rumqopg0	465	17	presence	presence	NN
cord-312486-rumqopg0	465	18	of	of	IN
cord-312486-rumqopg0	465	19	serum	serum	NN
cord-312486-rumqopg0	465	20	containing	contain	VBG
cord-312486-rumqopg0	465	21	specific	specific	JJ
cord-312486-rumqopg0	465	22	natural	natural	JJ
cord-312486-rumqopg0	465	23	antibodies	antibody	NNS
cord-312486-rumqopg0	465	24	and	and	CC
cord-312486-rumqopg0	465	25	complement	complement	VB
cord-312486-rumqopg0	465	26	The	the	DT
cord-312486-rumqopg0	465	27	vascular	vascular	JJ
cord-312486-rumqopg0	465	28	endothelium	endothelium	NN
cord-312486-rumqopg0	465	29	:	:	:
cord-312486-rumqopg0	465	30	the	the	DT
cord-312486-rumqopg0	465	31	cornerstone	cornerstone	NNP
cord-312486-rumqopg0	465	32	of	of	IN
cord-312486-rumqopg0	465	33	organ	organ	NN
cord-312486-rumqopg0	465	34	dysfunction	dysfunction	NN
cord-312486-rumqopg0	465	35	in	in	IN
cord-312486-rumqopg0	465	36	severe	severe	JJ
cord-312486-rumqopg0	465	37	SARS	SARS	NNP
cord-312486-rumqopg0	465	38	-	-	HYPH
cord-312486-rumqopg0	465	39	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	465	40	infection	infection	NN
cord-312486-rumqopg0	465	41	Inhibition	inhibition	NN
cord-312486-rumqopg0	465	42	of	of	IN
cord-312486-rumqopg0	465	43	SARS	SARS	NNP
cord-312486-rumqopg0	465	44	-	-	HYPH
cord-312486-rumqopg0	465	45	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	465	46	infections	infection	NNS
cord-312486-rumqopg0	465	47	in	in	IN
cord-312486-rumqopg0	465	48	engineered	engineer	VBN
cord-312486-rumqopg0	465	49	human	human	JJ
cord-312486-rumqopg0	465	50	tissues	tissue	NNS
cord-312486-rumqopg0	465	51	using	use	VBG
cord-312486-rumqopg0	465	52	clinical	clinical	JJ
cord-312486-rumqopg0	465	53	-	-	HYPH
cord-312486-rumqopg0	465	54	grade	grade	NN
cord-312486-rumqopg0	465	55	soluble	soluble	JJ
cord-312486-rumqopg0	465	56	human	human	JJ
cord-312486-rumqopg0	465	57	ACE2	ACE2	NNP
cord-312486-rumqopg0	465	58	Endothelial	Endothelial	NNP
cord-312486-rumqopg0	465	59	cell	cell	NN
cord-312486-rumqopg0	465	60	infection	infection	NN
cord-312486-rumqopg0	465	61	and	and	CC
cord-312486-rumqopg0	465	62	endotheliitis	endotheliitis	NN
cord-312486-rumqopg0	465	63	in	in	IN
cord-312486-rumqopg0	465	64	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	465	65	Pathophysiology	Pathophysiology	NNP
cord-312486-rumqopg0	465	66	of	of	IN
cord-312486-rumqopg0	465	67	SARS	SARS	NNP
cord-312486-rumqopg0	465	68	-	-	HYPH
cord-312486-rumqopg0	465	69	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	465	70	:	:	:
cord-312486-rumqopg0	465	71	targeting	target	VBG
cord-312486-rumqopg0	465	72	of	of	IN
cord-312486-rumqopg0	465	73	endothelial	endothelial	JJ
cord-312486-rumqopg0	465	74	cells	cell	NNS
cord-312486-rumqopg0	465	75	renders	render	VBZ
cord-312486-rumqopg0	465	76	a	a	DT
cord-312486-rumqopg0	465	77	complex	complex	JJ
cord-312486-rumqopg0	465	78	disease	disease	NN
cord-312486-rumqopg0	465	79	with	with	IN
cord-312486-rumqopg0	465	80	thrombotic	thrombotic	JJ
cord-312486-rumqopg0	465	81	microangiopathy	microangiopathy	NNP
cord-312486-rumqopg0	465	82	and	and	CC
cord-312486-rumqopg0	465	83	aberrant	aberrant	JJ
cord-312486-rumqopg0	465	84	immune	immune	JJ
cord-312486-rumqopg0	465	85	response	response	NN
cord-312486-rumqopg0	465	86	.	.	.
cord-312486-rumqopg0	466	1	The	the	DT
cord-312486-rumqopg0	466	2	Mount	Mount	NNP
cord-312486-rumqopg0	466	3	Sinai	Sinai	NNP
cord-312486-rumqopg0	466	4	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	466	5	autopsy	autopsy	JJ
cord-312486-rumqopg0	466	6	experience	experience	NN
cord-312486-rumqopg0	467	1	Endothelial	endothelial	JJ
cord-312486-rumqopg0	467	2	dysfunction	dysfunction	NN
cord-312486-rumqopg0	468	1	-a	-a	:
cord-312486-rumqopg0	468	2	marker	marker	NN
cord-312486-rumqopg0	468	3	of	of	IN
cord-312486-rumqopg0	468	4	atherosclerosis	atherosclerosis	NN
cord-312486-rumqopg0	468	5	risk	risk	NN
cord-312486-rumqopg0	468	6	Neutrophil	Neutrophil	NNP
cord-312486-rumqopg0	468	7	extracellular	extracellular	JJ
cord-312486-rumqopg0	468	8	traps	trap	NNS
cord-312486-rumqopg0	468	9	induce	induce	VBP
cord-312486-rumqopg0	468	10	endothelial	endothelial	JJ
cord-312486-rumqopg0	468	11	cell	cell	NN
cord-312486-rumqopg0	468	12	activation	activation	NN
cord-312486-rumqopg0	468	13	and	and	CC
cord-312486-rumqopg0	468	14	tissue	tissue	NN
cord-312486-rumqopg0	468	15	factor	factor	NN
cord-312486-rumqopg0	468	16	production	production	NN
cord-312486-rumqopg0	468	17	through	through	IN
cord-312486-rumqopg0	468	18	interleukin-1alpha	interleukin-1alpha	NN
cord-312486-rumqopg0	468	19	and	and	CC
cord-312486-rumqopg0	468	20	cathepsin	cathepsin	NN
cord-312486-rumqopg0	468	21	G	g	NN
cord-312486-rumqopg0	468	22	Endothelial	endothelial	NN
cord-312486-rumqopg0	468	23	cell	cell	NN
cord-312486-rumqopg0	468	24	responses	response	NNS
cord-312486-rumqopg0	468	25	to	to	IN
cord-312486-rumqopg0	468	26	hypoxia	hypoxia	NN
cord-312486-rumqopg0	468	27	:	:	:
cord-312486-rumqopg0	468	28	initiation	initiation	NN
cord-312486-rumqopg0	468	29	of	of	IN
cord-312486-rumqopg0	468	30	a	a	DT
cord-312486-rumqopg0	468	31	cascade	cascade	NN
cord-312486-rumqopg0	468	32	of	of	IN
cord-312486-rumqopg0	468	33	cellular	cellular	JJ
cord-312486-rumqopg0	468	34	interactions	interaction	NNS
cord-312486-rumqopg0	469	1	Neutrophil	Neutrophil	NNP
cord-312486-rumqopg0	469	2	extracellular	extracellular	JJ
cord-312486-rumqopg0	469	3	traps	trap	NNS
cord-312486-rumqopg0	469	4	in	in	IN
cord-312486-rumqopg0	469	5	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	469	6	Targeting	target	VBG
cord-312486-rumqopg0	469	7	potential	potential	JJ
cord-312486-rumqopg0	469	8	drivers	driver	NNS
cord-312486-rumqopg0	469	9	of	of	IN
cord-312486-rumqopg0	469	10	COVID-19	covid-19	NN
cord-312486-rumqopg0	469	11	:	:	:
cord-312486-rumqopg0	469	12	neutrophil	neutrophil	NN
cord-312486-rumqopg0	469	13	extracellular	extracellular	JJ
cord-312486-rumqopg0	469	14	traps	trap	NNS
cord-312486-rumqopg0	470	1	Severe	severe	JJ
cord-312486-rumqopg0	471	1	COVID-19	covid-19	JJ
cord-312486-rumqopg0	471	2	infection	infection	NN
cord-312486-rumqopg0	471	3	and	and	CC
cord-312486-rumqopg0	471	4	thrombotic	thrombotic	JJ
cord-312486-rumqopg0	471	5	microangiopathy	microangiopathy	NN
cord-312486-rumqopg0	471	6	:	:	:
cord-312486-rumqopg0	471	7	success	success	NN
cord-312486-rumqopg0	471	8	does	do	VBZ
cord-312486-rumqopg0	471	9	not	not	RB
cord-312486-rumqopg0	471	10	come	come	VB
cord-312486-rumqopg0	471	11	easily	easily	RB
cord-312486-rumqopg0	471	12	Clinical	clinical	JJ
cord-312486-rumqopg0	471	13	course	course	NN
cord-312486-rumqopg0	471	14	and	and	CC
cord-312486-rumqopg0	471	15	risk	risk	NN
cord-312486-rumqopg0	471	16	factors	factor	NNS
cord-312486-rumqopg0	471	17	for	for	IN
cord-312486-rumqopg0	471	18	mortality	mortality	NN
cord-312486-rumqopg0	471	19	of	of	IN
cord-312486-rumqopg0	471	20	adult	adult	NN
cord-312486-rumqopg0	471	21	inpatients	inpatient	NNS
cord-312486-rumqopg0	471	22	with	with	IN
cord-312486-rumqopg0	471	23	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	471	24	in	in	IN
cord-312486-rumqopg0	471	25	Wuhan	Wuhan	NNP
cord-312486-rumqopg0	471	26	,	,	,
cord-312486-rumqopg0	471	27	China	China	NNP
cord-312486-rumqopg0	471	28	:	:	:
cord-312486-rumqopg0	471	29	a	a	DT
cord-312486-rumqopg0	471	30	retrospective	retrospective	JJ
cord-312486-rumqopg0	471	31	cohort	cohort	NN
cord-312486-rumqopg0	471	32	study	study	NN
cord-312486-rumqopg0	471	33	Early	early	JJ
cord-312486-rumqopg0	471	34	predictors	predictor	NNS
cord-312486-rumqopg0	471	35	of	of	IN
cord-312486-rumqopg0	471	36	clinical	clinical	JJ
cord-312486-rumqopg0	471	37	outcomes	outcome	NNS
cord-312486-rumqopg0	471	38	of	of	IN
cord-312486-rumqopg0	471	39	COVID-19	covid-19	JJ
cord-312486-rumqopg0	471	40	outbreak	outbreak	NN
cord-312486-rumqopg0	471	41	in	in	IN
cord-312486-rumqopg0	471	42	Complement	complement	NN
cord-312486-rumqopg0	471	43	and	and	CC
cord-312486-rumqopg0	471	44	coagulation	coagulation	NN
cord-312486-rumqopg0	471	45	:	:	:
cord-312486-rumqopg0	471	46	cross	cross	NN
cord-312486-rumqopg0	471	47	talk	talk	NN
cord-312486-rumqopg0	471	48	through	through	IN
cord-312486-rumqopg0	471	49	time	time	NN
cord-312486-rumqopg0	471	50	Clinical	clinical	JJ
cord-312486-rumqopg0	471	51	and	and	CC
cord-312486-rumqopg0	471	52	autoimmune	autoimmune	JJ
cord-312486-rumqopg0	471	53	characteristics	characteristic	NNS
cord-312486-rumqopg0	471	54	of	of	IN
cord-312486-rumqopg0	471	55	severe	severe	JJ
cord-312486-rumqopg0	471	56	and	and	CC
cord-312486-rumqopg0	471	57	critical	critical	JJ
cord-312486-rumqopg0	471	58	cases	case	NNS
cord-312486-rumqopg0	471	59	of	of	IN
cord-312486-rumqopg0	471	60	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	471	61	Coagulopathy	Coagulopathy	NNP
cord-312486-rumqopg0	471	62	and	and	CC
cord-312486-rumqopg0	471	63	antiphospholipid	antiphospholipid	NNP
cord-312486-rumqopg0	471	64	antibodies	antibody	NNS
cord-312486-rumqopg0	471	65	in	in	IN
cord-312486-rumqopg0	471	66	patients	patient	NNS
cord-312486-rumqopg0	471	67	with	with	IN
cord-312486-rumqopg0	471	68	Covid-19	Covid-19	NNP
cord-312486-rumqopg0	471	69	High	high	JJ
cord-312486-rumqopg0	471	70	prevalence	prevalence	NN
cord-312486-rumqopg0	471	71	of	of	IN
cord-312486-rumqopg0	471	72	antinuclear	antinuclear	JJ
cord-312486-rumqopg0	471	73	antibodies	antibody	NNS
cord-312486-rumqopg0	471	74	and	and	CC
cord-312486-rumqopg0	471	75	lupus	lupus	NN
cord-312486-rumqopg0	471	76	anticoagulant	anticoagulant	NN
cord-312486-rumqopg0	471	77	in	in	IN
cord-312486-rumqopg0	471	78	patients	patient	NNS
cord-312486-rumqopg0	471	79	hospitalized	hospitalize	VBN
cord-312486-rumqopg0	471	80	for	for	IN
cord-312486-rumqopg0	471	81	SARS	SARS	NNP
cord-312486-rumqopg0	471	82	-	-	HYPH
cord-312486-rumqopg0	471	83	CoV2	CoV2	NNP
cord-312486-rumqopg0	471	84	pneumonia	pneumonia	NN
cord-312486-rumqopg0	471	85	International	international	JJ
cord-312486-rumqopg0	471	86	consensus	consensus	NN
cord-312486-rumqopg0	471	87	statement	statement	NN
cord-312486-rumqopg0	471	88	on	on	IN
cord-312486-rumqopg0	471	89	an	an	DT
cord-312486-rumqopg0	471	90	update	update	NN
cord-312486-rumqopg0	471	91	of	of	IN
cord-312486-rumqopg0	471	92	the	the	DT
cord-312486-rumqopg0	471	93	classification	classification	NN
cord-312486-rumqopg0	471	94	criteria	criterion	NNS
cord-312486-rumqopg0	471	95	for	for	IN
cord-312486-rumqopg0	471	96	definite	definite	JJ
cord-312486-rumqopg0	471	97	antiphospholipid	antiphospholipid	NNP
cord-312486-rumqopg0	471	98	syndrome	syndrome	NN
cord-312486-rumqopg0	471	99	(	(	-LRB-
cord-312486-rumqopg0	471	100	APS	APS	NNP
cord-312486-rumqopg0	471	101	)	)	-RRB-
cord-312486-rumqopg0	472	1	Viral	viral	JJ
cord-312486-rumqopg0	472	2	infections	infection	NNS
cord-312486-rumqopg0	472	3	and	and	CC
cord-312486-rumqopg0	472	4	their	-PRON-	PRP$
cord-312486-rumqopg0	472	5	relationship	relationship	NN
cord-312486-rumqopg0	472	6	with	with	IN
cord-312486-rumqopg0	472	7	catastrophic	catastrophic	JJ
cord-312486-rumqopg0	472	8	antiphospholipid	antiphospholipid	NNP
cord-312486-rumqopg0	472	9	syndrome	syndrome	NN
cord-312486-rumqopg0	472	10	:	:	:
cord-312486-rumqopg0	472	11	a	a	DT
cord-312486-rumqopg0	472	12	possible	possible	JJ
cord-312486-rumqopg0	472	13	pathogenic	pathogenic	JJ
cord-312486-rumqopg0	472	14	mechanism	mechanism	NN
cord-312486-rumqopg0	472	15	of	of	IN
cord-312486-rumqopg0	472	16	severe	severe	JJ
cord-312486-rumqopg0	472	17	COVID-19	covid-19	JJ
cord-312486-rumqopg0	472	18	thrombotic	thrombotic	JJ
cord-312486-rumqopg0	472	19	complications	complication	NNS
cord-312486-rumqopg0	472	20	Pulmonary	pulmonary	JJ
cord-312486-rumqopg0	472	21	intravascular	intravascular	JJ
cord-312486-rumqopg0	472	22	coagulopathy	coagulopathy	NN
cord-312486-rumqopg0	472	23	in	in	IN
cord-312486-rumqopg0	472	24	COVID-19	covid-19	JJ
cord-312486-rumqopg0	472	25	pneumonia	pneumonia	NN
cord-312486-rumqopg0	472	26	Immunothrombotic	Immunothrombotic	NNP
cord-312486-rumqopg0	472	27	dysregulation	dysregulation	NN
cord-312486-rumqopg0	472	28	in	in	IN
cord-312486-rumqopg0	473	1	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	473	2	pneumonia	pneumonia	NN
cord-312486-rumqopg0	473	3	is	be	VBZ
cord-312486-rumqopg0	473	4	associated	associate	VBN
cord-312486-rumqopg0	473	5	with	with	IN
cord-312486-rumqopg0	473	6	respiratory	respiratory	JJ
cord-312486-rumqopg0	473	7	failure	failure	NN
cord-312486-rumqopg0	473	8	and	and	CC
cord-312486-rumqopg0	473	9	coagulopathy	coagulopathy	NN
cord-312486-rumqopg0	473	10	Characteristics	characteristic	NNS
cord-312486-rumqopg0	473	11	of	of	IN
cord-312486-rumqopg0	473	12	peripheral	peripheral	JJ
cord-312486-rumqopg0	473	13	lymphocyte	lymphocyte	NN
cord-312486-rumqopg0	473	14	subset	subset	VBN
cord-312486-rumqopg0	473	15	alteration	alteration	NN
cord-312486-rumqopg0	473	16	in	in	IN
cord-312486-rumqopg0	473	17	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	473	18	pneumonia	pneumonia	NN
cord-312486-rumqopg0	473	19	Reduction	reduction	NN
cord-312486-rumqopg0	473	20	and	and	CC
cord-312486-rumqopg0	473	21	functional	functional	JJ
cord-312486-rumqopg0	473	22	exhaustion	exhaustion	NN
cord-312486-rumqopg0	473	23	of	of	IN
cord-312486-rumqopg0	473	24	T	T	NNP
cord-312486-rumqopg0	473	25	Cells	cell	NNS
cord-312486-rumqopg0	473	26	in	in	IN
cord-312486-rumqopg0	473	27	patients	patient	NNS
cord-312486-rumqopg0	473	28	with	with	IN
cord-312486-rumqopg0	473	29	Coronavirus	Coronavirus	NNP
cord-312486-rumqopg0	473	30	Disease	Disease	NNP
cord-312486-rumqopg0	473	31	2019	2019	CD
cord-312486-rumqopg0	473	32	(	(	-LRB-
cord-312486-rumqopg0	473	33	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	473	34	)	)	-RRB-
cord-312486-rumqopg0	473	35	Functional	functional	JJ
cord-312486-rumqopg0	473	36	exhaustion	exhaustion	NN
cord-312486-rumqopg0	473	37	of	of	IN
cord-312486-rumqopg0	473	38	antiviral	antiviral	JJ
cord-312486-rumqopg0	473	39	lymphocytes	lymphocyte	NNS
cord-312486-rumqopg0	473	40	in	in	IN
cord-312486-rumqopg0	473	41	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	473	42	patients	patient	NNS
cord-312486-rumqopg0	473	43	Clinical	clinical	JJ
cord-312486-rumqopg0	473	44	and	and	CC
cord-312486-rumqopg0	473	45	immunological	immunological	JJ
cord-312486-rumqopg0	473	46	features	feature	NNS
cord-312486-rumqopg0	473	47	of	of	IN
cord-312486-rumqopg0	473	48	severe	severe	JJ
cord-312486-rumqopg0	473	49	and	and	CC
cord-312486-rumqopg0	473	50	moderate	moderate	JJ
cord-312486-rumqopg0	473	51	coronavirus	coronavirus	NN
cord-312486-rumqopg0	473	52	disease	disease	NN
cord-312486-rumqopg0	473	53	2019	2019	CD
cord-312486-rumqopg0	473	54	Complex	complex	JJ
cord-312486-rumqopg0	473	55	immune	immune	JJ
cord-312486-rumqopg0	473	56	dysregulation	dysregulation	NN
cord-312486-rumqopg0	473	57	in	in	IN
cord-312486-rumqopg0	473	58	COVID-19	covid-19	JJ
cord-312486-rumqopg0	473	59	patients	patient	NNS
cord-312486-rumqopg0	473	60	with	with	IN
cord-312486-rumqopg0	473	61	severe	severe	JJ
cord-312486-rumqopg0	473	62	respiratory	respiratory	JJ
cord-312486-rumqopg0	473	63	failure	failure	NN
cord-312486-rumqopg0	474	1	Impaired	impaired	JJ
cord-312486-rumqopg0	474	2	immune	immune	JJ
cord-312486-rumqopg0	474	3	cell	cell	NN
cord-312486-rumqopg0	474	4	cytotoxicity	cytotoxicity	NN
cord-312486-rumqopg0	474	5	in	in	IN
cord-312486-rumqopg0	474	6	severe	severe	JJ
cord-312486-rumqopg0	474	7	COVID-19	covid-19	NN
cord-312486-rumqopg0	474	8	is	be	VBZ
cord-312486-rumqopg0	474	9	IL-6	IL-6	NNP
cord-312486-rumqopg0	474	10	dependent	dependent	JJ
cord-312486-rumqopg0	474	11	Coronaviruses	Coronaviruses	NNPS
cord-312486-rumqopg0	474	12	and	and	CC
cord-312486-rumqopg0	474	13	immunosuppressed	immunosuppressed	JJ
cord-312486-rumqopg0	474	14	patients	patient	NNS
cord-312486-rumqopg0	474	15	:	:	:
cord-312486-rumqopg0	474	16	the	the	DT
cord-312486-rumqopg0	474	17	facts	fact	NNS
cord-312486-rumqopg0	474	18	during	during	IN
cord-312486-rumqopg0	474	19	the	the	DT
cord-312486-rumqopg0	474	20	third	third	JJ
cord-312486-rumqopg0	474	21	epidemic	epidemic	NN
cord-312486-rumqopg0	475	1	Uneventful	uneventful	JJ
cord-312486-rumqopg0	475	2	course	course	NN
cord-312486-rumqopg0	475	3	in	in	IN
cord-312486-rumqopg0	475	4	patients	patient	NNS
cord-312486-rumqopg0	475	5	with	with	IN
cord-312486-rumqopg0	475	6	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	475	7	bowel	bowel	NN
cord-312486-rumqopg0	475	8	disease	disease	NN
cord-312486-rumqopg0	475	9	during	during	IN
cord-312486-rumqopg0	475	10	the	the	DT
cord-312486-rumqopg0	475	11	severe	severe	JJ
cord-312486-rumqopg0	475	12	acute	acute	JJ
cord-312486-rumqopg0	475	13	respiratory	respiratory	JJ
cord-312486-rumqopg0	475	14	syndrome	syndrome	NN
cord-312486-rumqopg0	475	15	coronavirus	coronavirus	NN
cord-312486-rumqopg0	475	16	2	2	CD
cord-312486-rumqopg0	475	17	Outbreak	outbreak	NN
cord-312486-rumqopg0	475	18	in	in	IN
cord-312486-rumqopg0	475	19	Northern	Northern	NNP
cord-312486-rumqopg0	475	20	Italy	Italy	NNP
cord-312486-rumqopg0	475	21	Single	single	JJ
cord-312486-rumqopg0	475	22	-	-	HYPH
cord-312486-rumqopg0	475	23	cell	cell	NN
cord-312486-rumqopg0	475	24	landscape	landscape	NN
cord-312486-rumqopg0	475	25	of	of	IN
cord-312486-rumqopg0	475	26	bronchoalveolar	bronchoalveolar	JJ
cord-312486-rumqopg0	475	27	immune	immune	JJ
cord-312486-rumqopg0	475	28	cells	cell	NNS
cord-312486-rumqopg0	475	29	in	in	IN
cord-312486-rumqopg0	475	30	patients	patient	NNS
cord-312486-rumqopg0	475	31	with	with	IN
cord-312486-rumqopg0	475	32	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	475	33	The	the	DT
cord-312486-rumqopg0	475	34	novel	novel	JJ
cord-312486-rumqopg0	475	35	severe	severe	JJ
cord-312486-rumqopg0	475	36	acute	acute	JJ
cord-312486-rumqopg0	475	37	respiratory	respiratory	JJ
cord-312486-rumqopg0	475	38	syndrome	syndrome	NN
cord-312486-rumqopg0	475	39	coronavirus	coronavirus	NN
cord-312486-rumqopg0	475	40	2	2	CD
cord-312486-rumqopg0	476	1	(	(	-LRB-
cord-312486-rumqopg0	476	2	SARS	SARS	NNP
cord-312486-rumqopg0	476	3	-	-	HYPH
cord-312486-rumqopg0	476	4	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	476	5	)	)	-RRB-
cord-312486-rumqopg0	476	6	directly	directly	RB
cord-312486-rumqopg0	476	7	decimates	decimate	VBZ
cord-312486-rumqopg0	476	8	human	human	JJ
cord-312486-rumqopg0	476	9	spleens	spleen	NNS
cord-312486-rumqopg0	476	10	and	and	CC
cord-312486-rumqopg0	476	11	lymph	lymph	NN
cord-312486-rumqopg0	476	12	nodes	node	NNS
cord-312486-rumqopg0	477	1	Deep	deep	JJ
cord-312486-rumqopg0	477	2	immune	immune	JJ
cord-312486-rumqopg0	477	3	profiling	profiling	NN
cord-312486-rumqopg0	477	4	of	of	IN
cord-312486-rumqopg0	477	5	COVID-19	covid-19	JJ
cord-312486-rumqopg0	477	6	patients	patient	NNS
cord-312486-rumqopg0	477	7	reveals	reveal	VBZ
cord-312486-rumqopg0	477	8	distinct	distinct	JJ
cord-312486-rumqopg0	477	9	immunotypes	immunotype	NNS
cord-312486-rumqopg0	477	10	with	with	IN
cord-312486-rumqopg0	477	11	therapeutic	therapeutic	JJ
cord-312486-rumqopg0	477	12	implication	implication	NN
cord-312486-rumqopg0	478	1	Longitudinal	longitudinal	JJ
cord-312486-rumqopg0	478	2	analyses	analysis	NNS
cord-312486-rumqopg0	478	3	reveal	reveal	VBP
cord-312486-rumqopg0	478	4	immunological	immunological	JJ
cord-312486-rumqopg0	478	5	misfiring	misfiring	NN
cord-312486-rumqopg0	478	6	in	in	IN
cord-312486-rumqopg0	478	7	severe	severe	JJ
cord-312486-rumqopg0	478	8	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	478	9	Mouse	Mouse	NNP
cord-312486-rumqopg0	478	10	model	model	NN
cord-312486-rumqopg0	478	11	of	of	IN
cord-312486-rumqopg0	478	12	SARS	SARS	NNP
cord-312486-rumqopg0	478	13	-	-	HYPH
cord-312486-rumqopg0	478	14	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	479	1	reveals	reveal	VBZ
cord-312486-rumqopg0	479	2	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	479	3	role	role	NN
cord-312486-rumqopg0	479	4	of	of	IN
cord-312486-rumqopg0	479	5	type	type	NN
cord-312486-rumqopg0	479	6	I	-PRON-	PRP
cord-312486-rumqopg0	479	7	Interferon	Interferon	NNP
cord-312486-rumqopg0	479	8	signaling	signal	VBG
cord-312486-rumqopg0	479	9	Persistence	persistence	NN
cord-312486-rumqopg0	479	10	of	of	IN
cord-312486-rumqopg0	479	11	memory	memory	NN
cord-312486-rumqopg0	479	12	in	in	IN
cord-312486-rumqopg0	479	13	times	time	NNS
cord-312486-rumqopg0	479	14	of	of	IN
cord-312486-rumqopg0	479	15	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	479	16	Targets	Targets	NNPS
cord-312486-rumqopg0	479	17	of	of	IN
cord-312486-rumqopg0	479	18	T	T	NNP
cord-312486-rumqopg0	479	19	cell	cell	NN
cord-312486-rumqopg0	479	20	responses	response	NNS
cord-312486-rumqopg0	479	21	to	to	IN
cord-312486-rumqopg0	479	22	SARS	SARS	NNP
cord-312486-rumqopg0	479	23	-	-	HYPH
cord-312486-rumqopg0	479	24	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	479	25	coronavirus	coronavirus	NN
cord-312486-rumqopg0	479	26	in	in	IN
cord-312486-rumqopg0	479	27	humans	human	NNS
cord-312486-rumqopg0	479	28	with	with	IN
cord-312486-rumqopg0	479	29	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	479	30	disease	disease	NN
cord-312486-rumqopg0	479	31	and	and	CC
cord-312486-rumqopg0	479	32	unexposed	unexposed	JJ
cord-312486-rumqopg0	479	33	individuals	individual	NNS
cord-312486-rumqopg0	479	34	SARS	SARS	NNP
cord-312486-rumqopg0	479	35	-	-	HYPH
cord-312486-rumqopg0	479	36	CoV-2-specific	CoV-2-specific	NNP
cord-312486-rumqopg0	479	37	T	t	NN
cord-312486-rumqopg0	479	38	cell	cell	NN
cord-312486-rumqopg0	479	39	immunity	immunity	NN
cord-312486-rumqopg0	479	40	in	in	IN
cord-312486-rumqopg0	479	41	cases	case	NNS
cord-312486-rumqopg0	479	42	of	of	IN
cord-312486-rumqopg0	479	43	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	479	44	and	and	CC
cord-312486-rumqopg0	479	45	SARS	SARS	NNP
cord-312486-rumqopg0	479	46	,	,	,
cord-312486-rumqopg0	479	47	and	and	CC
cord-312486-rumqopg0	479	48	uninfected	uninfected	JJ
cord-312486-rumqopg0	479	49	controls	control	NNS
cord-312486-rumqopg0	480	1	No	no	DT
cord-312486-rumqopg0	480	2	one	one	NN
cord-312486-rumqopg0	480	3	is	be	VBZ
cord-312486-rumqopg0	480	4	naïve	naïve	JJ
cord-312486-rumqopg0	480	5	:	:	:
cord-312486-rumqopg0	480	6	the	the	DT
cord-312486-rumqopg0	480	7	significance	significance	NN
cord-312486-rumqopg0	480	8	of	of	IN
cord-312486-rumqopg0	480	9	heterologous	heterologous	NNP
cord-312486-rumqopg0	480	10	T	T	NNP
cord-312486-rumqopg0	480	11	-	-	HYPH
cord-312486-rumqopg0	480	12	cell	cell	NN
cord-312486-rumqopg0	480	13	immunity	immunity	NN
cord-312486-rumqopg0	480	14	Heterologous	Heterologous	NNP
cord-312486-rumqopg0	480	15	immunity	immunity	NN
cord-312486-rumqopg0	480	16	between	between	IN
cord-312486-rumqopg0	480	17	viruses	virus	NNS
cord-312486-rumqopg0	480	18	Heterologous	Heterologous	NNP
cord-312486-rumqopg0	480	19	T	t	NN
cord-312486-rumqopg0	480	20	cell	cell	NN
cord-312486-rumqopg0	480	21	immunity	immunity	NN
cord-312486-rumqopg0	480	22	in	in	IN
cord-312486-rumqopg0	480	23	severe	severe	JJ
cord-312486-rumqopg0	480	24	hepatitis	hepatitis	NN
cord-312486-rumqopg0	480	25	C	c	NN
cord-312486-rumqopg0	480	26	virus	virus	NN
cord-312486-rumqopg0	480	27	infection	infection	NN
cord-312486-rumqopg0	480	28	Immune	immune	JJ
cord-312486-rumqopg0	480	29	cell	cell	NN
cord-312486-rumqopg0	480	30	profiling	profiling	NN
cord-312486-rumqopg0	480	31	of	of	IN
cord-312486-rumqopg0	480	32	COVID-19	covid-19	JJ
cord-312486-rumqopg0	480	33	patients	patient	NNS
cord-312486-rumqopg0	480	34	in	in	IN
cord-312486-rumqopg0	480	35	the	the	DT
cord-312486-rumqopg0	480	36	recovery	recovery	NN
cord-312486-rumqopg0	480	37	stage	stage	NN
cord-312486-rumqopg0	480	38	by	by	IN
cord-312486-rumqopg0	480	39	single	single	JJ
cord-312486-rumqopg0	480	40	-	-	HYPH
cord-312486-rumqopg0	480	41	cell	cell	NN
cord-312486-rumqopg0	480	42	sequencing	sequencing	NN
cord-312486-rumqopg0	480	43	Neutralizing	neutralize	VBG
cord-312486-rumqopg0	480	44	Antibody	Antibody	NNP
cord-312486-rumqopg0	480	45	Responses	response	NNS
cord-312486-rumqopg0	480	46	to	to	IN
cord-312486-rumqopg0	480	47	SARS	SARS	NNP
cord-312486-rumqopg0	480	48	-	-	HYPH
cord-312486-rumqopg0	480	49	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	480	50	in	in	IN
cord-312486-rumqopg0	480	51	a	a	DT
cord-312486-rumqopg0	480	52	COVID-19	covid-19	JJ
cord-312486-rumqopg0	480	53	recovered	recover	VBN
cord-312486-rumqopg0	480	54	patient	patient	JJ
cord-312486-rumqopg0	480	55	cohort	cohort	NN
cord-312486-rumqopg0	480	56	and	and	CC
cord-312486-rumqopg0	480	57	their	-PRON-	PRP$
cord-312486-rumqopg0	480	58	implications	implication	NNS
cord-312486-rumqopg0	480	59	Convergent	convergent	JJ
cord-312486-rumqopg0	480	60	antibody	antibody	NN
cord-312486-rumqopg0	480	61	responses	response	NNS
cord-312486-rumqopg0	480	62	to	to	IN
cord-312486-rumqopg0	480	63	SARS	SARS	NNP
cord-312486-rumqopg0	480	64	-	-	HYPH
cord-312486-rumqopg0	480	65	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	480	66	in	in	IN
cord-312486-rumqopg0	480	67	convalescent	convalescent	JJ
cord-312486-rumqopg0	480	68	individuals	individual	NNS
cord-312486-rumqopg0	480	69	Clinical	clinical	JJ
cord-312486-rumqopg0	480	70	and	and	CC
cord-312486-rumqopg0	480	71	immunological	immunological	JJ
cord-312486-rumqopg0	480	72	assessment	assessment	NN
cord-312486-rumqopg0	480	73	of	of	IN
cord-312486-rumqopg0	480	74	asymptomatic	asymptomatic	JJ
cord-312486-rumqopg0	480	75	SARS	SARS	NNP
cord-312486-rumqopg0	480	76	-	-	HYPH
cord-312486-rumqopg0	480	77	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	480	78	infections	infection	NNS
cord-312486-rumqopg0	480	79	Antibody	Antibody	NNP
cord-312486-rumqopg0	480	80	responses	response	NNS
cord-312486-rumqopg0	480	81	to	to	IN
cord-312486-rumqopg0	480	82	SARS	SARS	NNP
cord-312486-rumqopg0	480	83	-	-	HYPH
cord-312486-rumqopg0	480	84	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	480	85	in	in	IN
cord-312486-rumqopg0	480	86	patients	patient	NNS
cord-312486-rumqopg0	480	87	of	of	IN
cord-312486-rumqopg0	480	88	novel	novel	JJ
cord-312486-rumqopg0	480	89	coronavirus	coronavirus	NN
cord-312486-rumqopg0	480	90	disease	disease	NN
cord-312486-rumqopg0	480	91	2019	2019	CD
cord-312486-rumqopg0	480	92	SARS	SARS	NNP
cord-312486-rumqopg0	480	93	-	-	HYPH
cord-312486-rumqopg0	480	94	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	480	95	proteome	proteome	NN
cord-312486-rumqopg0	480	96	microarray	microarray	NN
cord-312486-rumqopg0	480	97	for	for	IN
cord-312486-rumqopg0	480	98	global	global	JJ
cord-312486-rumqopg0	480	99	profiling	profiling	NN
cord-312486-rumqopg0	480	100	of	of	IN
cord-312486-rumqopg0	480	101	COVID-19	covid-19	DT
cord-312486-rumqopg0	480	102	specific	specific	JJ
cord-312486-rumqopg0	480	103	IgG	IgG	NNP
cord-312486-rumqopg0	480	104	and	and	CC
cord-312486-rumqopg0	480	105	IgM	IgM	NNP
cord-312486-rumqopg0	480	106	responses	response	NNS
cord-312486-rumqopg0	481	1	Viral	viral	JJ
cord-312486-rumqopg0	481	2	kinetics	kinetic	NNS
cord-312486-rumqopg0	481	3	and	and	CC
cord-312486-rumqopg0	481	4	antibody	antibody	NN
cord-312486-rumqopg0	481	5	responses	response	NNS
cord-312486-rumqopg0	481	6	in	in	IN
cord-312486-rumqopg0	481	7	patients	patient	NNS
cord-312486-rumqopg0	481	8	with	with	IN
cord-312486-rumqopg0	481	9	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	481	10	.	.	.
cord-312486-rumqopg0	482	1	medRxiv	medRxiv	NNP
cord-312486-rumqopg0	482	2	Serum	Serum	NNP
cord-312486-rumqopg0	482	3	IgA	IgA	NNP
cord-312486-rumqopg0	482	4	,	,	,
cord-312486-rumqopg0	482	5	IgM	IgM	NNP
cord-312486-rumqopg0	482	6	,	,	,
cord-312486-rumqopg0	482	7	and	and	CC
cord-312486-rumqopg0	482	8	IgG	IgG	NNP
cord-312486-rumqopg0	482	9	responses	response	NNS
cord-312486-rumqopg0	482	10	in	in	IN
cord-312486-rumqopg0	482	11	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	482	12	Anti	Anti	NNP
cord-312486-rumqopg0	482	13	-	-	NNP
cord-312486-rumqopg0	482	14	SARS	SARS	NNP
cord-312486-rumqopg0	482	15	-	-	HYPH
cord-312486-rumqopg0	482	16	CoV	CoV	NNP
cord-312486-rumqopg0	482	17	IgG	IgG	NNP
cord-312486-rumqopg0	482	18	response	response	NN
cord-312486-rumqopg0	482	19	in	in	IN
cord-312486-rumqopg0	482	20	relation	relation	NN
cord-312486-rumqopg0	482	21	to	to	IN
cord-312486-rumqopg0	482	22	disease	disease	NN
cord-312486-rumqopg0	482	23	severity	severity	NN
cord-312486-rumqopg0	482	24	of	of	IN
cord-312486-rumqopg0	482	25	severe	severe	JJ
cord-312486-rumqopg0	482	26	acute	acute	JJ
cord-312486-rumqopg0	482	27	respiratory	respiratory	JJ
cord-312486-rumqopg0	482	28	syndrome	syndrome	NN
cord-312486-rumqopg0	482	29	Anti	anti	JJ
cord-312486-rumqopg0	482	30	-	-	JJ
cord-312486-rumqopg0	482	31	spike	spike	JJ
cord-312486-rumqopg0	482	32	IgG	igg	NN
cord-312486-rumqopg0	482	33	causes	cause	VBZ
cord-312486-rumqopg0	482	34	severe	severe	JJ
cord-312486-rumqopg0	482	35	acute	acute	JJ
cord-312486-rumqopg0	482	36	lung	lung	NN
cord-312486-rumqopg0	482	37	injury	injury	NN
cord-312486-rumqopg0	482	38	by	by	IN
cord-312486-rumqopg0	482	39	skewing	skew	VBG
cord-312486-rumqopg0	482	40	macrophage	macrophage	NN
cord-312486-rumqopg0	482	41	responses	response	NNS
cord-312486-rumqopg0	482	42	during	during	IN
cord-312486-rumqopg0	482	43	acute	acute	JJ
cord-312486-rumqopg0	482	44	SARS	SARS	NNP
cord-312486-rumqopg0	482	45	-	-	HYPH
cord-312486-rumqopg0	482	46	CoV	CoV	NNP
cord-312486-rumqopg0	482	47	infection	infection	NN
cord-312486-rumqopg0	482	48	Antibodydependent	Antibodydependent	NNP
cord-312486-rumqopg0	482	49	infection	infection	NN
cord-312486-rumqopg0	482	50	of	of	IN
cord-312486-rumqopg0	482	51	human	human	JJ
cord-312486-rumqopg0	482	52	macrophages	macrophage	NNS
cord-312486-rumqopg0	482	53	by	by	IN
cord-312486-rumqopg0	482	54	severe	severe	JJ
cord-312486-rumqopg0	482	55	acute	acute	JJ
cord-312486-rumqopg0	482	56	respiratory	respiratory	JJ
cord-312486-rumqopg0	482	57	syndrome	syndrome	NN
cord-312486-rumqopg0	482	58	coronavirus	coronavirus	NN
cord-312486-rumqopg0	482	59	Molecular	Molecular	NNP
cord-312486-rumqopg0	482	60	mechanism	mechanism	NN
cord-312486-rumqopg0	482	61	for	for	IN
cord-312486-rumqopg0	482	62	antibodydependent	antibodydependent	NN
cord-312486-rumqopg0	482	63	enhancement	enhancement	NN
cord-312486-rumqopg0	482	64	of	of	IN
cord-312486-rumqopg0	482	65	coronavirus	coronavirus	NN
cord-312486-rumqopg0	482	66	entry	entry	NN
cord-312486-rumqopg0	482	67	Clinical	clinical	JJ
cord-312486-rumqopg0	482	68	efficiency	efficiency	NN
cord-312486-rumqopg0	482	69	of	of	IN
cord-312486-rumqopg0	482	70	intravenous	intravenous	JJ
cord-312486-rumqopg0	482	71	immunoglobulin	immunoglobulin	NN
cord-312486-rumqopg0	482	72	therapy	therapy	NN
cord-312486-rumqopg0	482	73	in	in	IN
cord-312486-rumqopg0	482	74	critical	critical	JJ
cord-312486-rumqopg0	482	75	patients	patient	NNS
cord-312486-rumqopg0	482	76	with	with	IN
cord-312486-rumqopg0	482	77	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	482	78	:	:	:
cord-312486-rumqopg0	482	79	a	a	DT
cord-312486-rumqopg0	482	80	multicenter	multicenter	JJ
cord-312486-rumqopg0	482	81	retrospective	retrospective	JJ
cord-312486-rumqopg0	482	82	cohort	cohort	NN
cord-312486-rumqopg0	482	83	study	study	NN
cord-312486-rumqopg0	482	84	The	the	DT
cord-312486-rumqopg0	482	85	potential	potential	JJ
cord-312486-rumqopg0	482	86	danger	danger	NN
cord-312486-rumqopg0	482	87	of	of	IN
cord-312486-rumqopg0	482	88	suboptimal	suboptimal	JJ
cord-312486-rumqopg0	482	89	antibody	antibody	NN
cord-312486-rumqopg0	482	90	responses	response	NNS
cord-312486-rumqopg0	482	91	in	in	IN
cord-312486-rumqopg0	482	92	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	482	93	Frequency	Frequency	NNP
cord-312486-rumqopg0	482	94	of	of	IN
cord-312486-rumqopg0	482	95	infection	infection	NN
cord-312486-rumqopg0	482	96	in	in	IN
cord-312486-rumqopg0	482	97	patients	patient	NNS
cord-312486-rumqopg0	482	98	with	with	IN
cord-312486-rumqopg0	482	99	Rheumatoid	Rheumatoid	NNP
cord-312486-rumqopg0	482	100	Arthritis	arthritis	NN
cord-312486-rumqopg0	482	101	compared	compare	VBN
cord-312486-rumqopg0	482	102	with	with	IN
cord-312486-rumqopg0	482	103	controls	control	NNS
cord-312486-rumqopg0	482	104	:	:	:
cord-312486-rumqopg0	482	105	a	a	DT
cord-312486-rumqopg0	482	106	population	population	NN
cord-312486-rumqopg0	482	107	study	study	NN
cord-312486-rumqopg0	482	108	Risk	risk	NN
cord-312486-rumqopg0	482	109	of	of	IN
cord-312486-rumqopg0	482	110	severe	severe	JJ
cord-312486-rumqopg0	482	111	herpes	herpes	NN
cord-312486-rumqopg0	482	112	simplex	simplex	NN
cord-312486-rumqopg0	482	113	virus	virus	NN
cord-312486-rumqopg0	482	114	infection	infection	NN
cord-312486-rumqopg0	482	115	in	in	IN
cord-312486-rumqopg0	482	116	SLE	SLE	NNP
cord-312486-rumqopg0	482	117	:	:	:
cord-312486-rumqopg0	482	118	analysis	analysis	NN
cord-312486-rumqopg0	482	119	of	of	IN
cord-312486-rumqopg0	482	120	epidemiology	epidemiology	NN
cord-312486-rumqopg0	482	121	and	and	CC
cord-312486-rumqopg0	482	122	risk	risk	NN
cord-312486-rumqopg0	482	123	factors	factor	NNS
cord-312486-rumqopg0	482	124	analysis	analysis	NN
cord-312486-rumqopg0	482	125	in	in	IN
cord-312486-rumqopg0	482	126	Taiwan	Taiwan	NNP
cord-312486-rumqopg0	482	127	Incidence	Incidence	NNP
cord-312486-rumqopg0	482	128	of	of	IN
cord-312486-rumqopg0	482	129	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	482	130	in	in	IN
cord-312486-rumqopg0	482	131	patients	patient	NNS
cord-312486-rumqopg0	482	132	with	with	IN
cord-312486-rumqopg0	482	133	rheumatic	rheumatic	JJ
cord-312486-rumqopg0	482	134	diseases	disease	NNS
cord-312486-rumqopg0	482	135	treated	treat	VBN
cord-312486-rumqopg0	482	136	with	with	IN
cord-312486-rumqopg0	482	137	targeted	targeted	JJ
cord-312486-rumqopg0	482	138	immunosuppressive	immunosuppressive	JJ
cord-312486-rumqopg0	482	139	drugs	drug	NNS
cord-312486-rumqopg0	482	140	:	:	:
cord-312486-rumqopg0	482	141	what	what	WP
cord-312486-rumqopg0	482	142	can	can	MD
cord-312486-rumqopg0	482	143	we	-PRON-	PRP
cord-312486-rumqopg0	482	144	learn	learn	VB
cord-312486-rumqopg0	482	145	from	from	IN
cord-312486-rumqopg0	482	146	observational	observational	JJ
cord-312486-rumqopg0	482	147	data	datum	NNS
cord-312486-rumqopg0	482	148	?	?	.
cord-312486-rumqopg0	483	1	Management	management	NN
cord-312486-rumqopg0	483	2	of	of	IN
cord-312486-rumqopg0	483	3	patients	patient	NNS
cord-312486-rumqopg0	483	4	with	with	IN
cord-312486-rumqopg0	483	5	Crohn	Crohn	NNP
cord-312486-rumqopg0	483	6	's	's	POS
cord-312486-rumqopg0	483	7	Disease	Disease	NNP
cord-312486-rumqopg0	483	8	and	and	CC
cord-312486-rumqopg0	483	9	Ulcerative	Ulcerative	NNP
cord-312486-rumqopg0	483	10	Colitis	Colitis	NNP
cord-312486-rumqopg0	483	11	during	during	IN
cord-312486-rumqopg0	483	12	the	the	DT
cord-312486-rumqopg0	483	13	coronavirus	coronavirus	NN
cord-312486-rumqopg0	483	14	disease-2019	disease-2019	NNP
cord-312486-rumqopg0	483	15	pandemic	pandemic	NN
cord-312486-rumqopg0	483	16	:	:	:
cord-312486-rumqopg0	483	17	results	result	NNS
cord-312486-rumqopg0	483	18	of	of	IN
cord-312486-rumqopg0	483	19	an	an	DT
cord-312486-rumqopg0	483	20	international	international	JJ
cord-312486-rumqopg0	483	21	meeting	meeting	NN
cord-312486-rumqopg0	483	22	Factors	factor	NNS
cord-312486-rumqopg0	483	23	associated	associate	VBN
cord-312486-rumqopg0	483	24	with	with	IN
cord-312486-rumqopg0	483	25	COVID-19-related	covid-19-related	JJ
cord-312486-rumqopg0	483	26	death	death	NN
cord-312486-rumqopg0	483	27	using	use	VBG
cord-312486-rumqopg0	483	28	OpenSAFELY	OpenSAFELY	NNP
cord-312486-rumqopg0	483	29	Epigenetic	epigenetic	JJ
cord-312486-rumqopg0	483	30	dysregulation	dysregulation	NN
cord-312486-rumqopg0	483	31	of	of	IN
cord-312486-rumqopg0	483	32	ACE2	ACE2	NNP
cord-312486-rumqopg0	483	33	and	and	CC
cord-312486-rumqopg0	483	34	interferon	interferon	NN
cord-312486-rumqopg0	483	35	-	-	HYPH
cord-312486-rumqopg0	483	36	regulated	regulate	VBN
cord-312486-rumqopg0	483	37	genes	gene	NNS
cord-312486-rumqopg0	483	38	might	may	MD
cord-312486-rumqopg0	483	39	suggest	suggest	VB
cord-312486-rumqopg0	483	40	increased	increase	VBN
cord-312486-rumqopg0	483	41	COVID-19	covid-19	JJ
cord-312486-rumqopg0	483	42	susceptibility	susceptibility	NN
cord-312486-rumqopg0	483	43	and	and	CC
cord-312486-rumqopg0	483	44	severity	severity	NN
cord-312486-rumqopg0	483	45	in	in	IN
cord-312486-rumqopg0	483	46	lupus	lupus	NN
cord-312486-rumqopg0	483	47	patients	patient	NNS
cord-312486-rumqopg0	483	48	On	on	IN
cord-312486-rumqopg0	483	49	the	the	DT
cord-312486-rumqopg0	483	50	alert	alert	NN
cord-312486-rumqopg0	483	51	for	for	IN
cord-312486-rumqopg0	483	52	cytokine	cytokine	JJ
cord-312486-rumqopg0	483	53	storm	storm	NN
cord-312486-rumqopg0	483	54	:	:	:
cord-312486-rumqopg0	483	55	immunopathology	immunopathology	NN
cord-312486-rumqopg0	483	56	in	in	IN
cord-312486-rumqopg0	483	57	COVID-19	COVID-19	NNP
cord-312486-rumqopg0	483	58	COVID-19-induced	COVID-19-induced	NNP
cord-312486-rumqopg0	483	59	acute	acute	JJ
cord-312486-rumqopg0	483	60	respiratory	respiratory	JJ
cord-312486-rumqopg0	483	61	failure	failure	NN
cord-312486-rumqopg0	483	62	-	-	:
cord-312486-rumqopg0	483	63	an	an	DT
cord-312486-rumqopg0	483	64	exacerbation	exacerbation	NN
cord-312486-rumqopg0	483	65	of	of	IN
cord-312486-rumqopg0	483	66	organ	organ	NN
cord-312486-rumqopg0	483	67	-	-	HYPH
cord-312486-rumqopg0	483	68	specific	specific	JJ
cord-312486-rumqopg0	483	69	autoimmunity	autoimmunity	NN
cord-312486-rumqopg0	483	70	?	?	.
cord-312486-rumqopg0	484	1	medRxiv	medRxiv	NNS
cord-312486-rumqopg0	484	2	High	high	JJ
cord-312486-rumqopg0	484	3	risk	risk	NN
cord-312486-rumqopg0	484	4	of	of	IN
cord-312486-rumqopg0	484	5	thrombosis	thrombosis	NN
cord-312486-rumqopg0	484	6	in	in	IN
cord-312486-rumqopg0	484	7	patients	patient	NNS
cord-312486-rumqopg0	484	8	with	with	IN
cord-312486-rumqopg0	484	9	severe	severe	JJ
cord-312486-rumqopg0	484	10	SARS	SARS	NNP
cord-312486-rumqopg0	484	11	-	-	HYPH
cord-312486-rumqopg0	484	12	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	484	13	infection	infection	NN
cord-312486-rumqopg0	484	14	:	:	:
cord-312486-rumqopg0	485	1	a	a	DT
cord-312486-rumqopg0	485	2	multicenter	multicenter	JJ
cord-312486-rumqopg0	485	3	prospective	prospective	JJ
cord-312486-rumqopg0	485	4	cohort	cohort	NN
cord-312486-rumqopg0	485	5	study	study	NN
cord-312486-rumqopg0	485	6	An	an	DT
cord-312486-rumqopg0	485	7	outbreak	outbreak	NN
cord-312486-rumqopg0	485	8	of	of	IN
cord-312486-rumqopg0	485	9	severe	severe	JJ
cord-312486-rumqopg0	485	10	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	485	11	-	-	HYPH
cord-312486-rumqopg0	485	12	like	like	JJ
cord-312486-rumqopg0	485	13	disease	disease	NN
cord-312486-rumqopg0	485	14	at	at	IN
cord-312486-rumqopg0	485	15	the	the	DT
cord-312486-rumqopg0	485	16	Italian	italian	JJ
cord-312486-rumqopg0	485	17	epicenter	epicenter	NN
cord-312486-rumqopg0	485	18	of	of	IN
cord-312486-rumqopg0	485	19	the	the	DT
cord-312486-rumqopg0	485	20	SARS	SARS	NNP
cord-312486-rumqopg0	485	21	-	-	HYPH
cord-312486-rumqopg0	485	22	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	485	23	epidemic	epidemic	NN
cord-312486-rumqopg0	485	24	:	:	:
cord-312486-rumqopg0	486	1	an	an	DT
cord-312486-rumqopg0	486	2	observational	observational	JJ
cord-312486-rumqopg0	486	3	cohort	cohort	NN
cord-312486-rumqopg0	486	4	study	study	NN
cord-312486-rumqopg0	486	5	Clinical	clinical	JJ
cord-312486-rumqopg0	486	6	characteristics	characteristic	NNS
cord-312486-rumqopg0	486	7	of	of	IN
cord-312486-rumqopg0	486	8	58	58	CD
cord-312486-rumqopg0	486	9	children	child	NNS
cord-312486-rumqopg0	486	10	with	with	IN
cord-312486-rumqopg0	486	11	a	a	DT
cord-312486-rumqopg0	486	12	pediatric	pediatric	JJ
cord-312486-rumqopg0	486	13	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	486	14	multisystem	multisystem	JJ
cord-312486-rumqopg0	486	15	syndrome	syndrome	NN
cord-312486-rumqopg0	486	16	temporally	temporally	RB
cord-312486-rumqopg0	486	17	associated	associate	VBN
cord-312486-rumqopg0	486	18	with	with	IN
cord-312486-rumqopg0	486	19	SARS	SARS	NNP
cord-312486-rumqopg0	486	20	-	-	HYPH
cord-312486-rumqopg0	486	21	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	486	22	Multisystem	Multisystem	NNP
cord-312486-rumqopg0	486	23	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	486	24	syndrome	syndrome	NN
cord-312486-rumqopg0	486	25	in	in	IN
cord-312486-rumqopg0	486	26	children	child	NNS
cord-312486-rumqopg0	486	27	in	in	IN
cord-312486-rumqopg0	486	28	New	New	NNP
cord-312486-rumqopg0	486	29	York	York	NNP
cord-312486-rumqopg0	486	30	State	State	NNP
cord-312486-rumqopg0	486	31	Multisystem	Multisystem	NNP
cord-312486-rumqopg0	486	32	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	486	33	syndrome	syndrome	NN
cord-312486-rumqopg0	486	34	in	in	IN
cord-312486-rumqopg0	486	35	U.S.	U.S.	NNP
cord-312486-rumqopg0	486	36	children	child	NNS
cord-312486-rumqopg0	486	37	and	and	CC
cord-312486-rumqopg0	486	38	adolescents	adolescent	NNS
cord-312486-rumqopg0	486	39	Acute	acute	JJ
cord-312486-rumqopg0	486	40	heart	heart	NN
cord-312486-rumqopg0	486	41	failure	failure	NN
cord-312486-rumqopg0	486	42	in	in	IN
cord-312486-rumqopg0	486	43	multisystem	multisystem	JJ
cord-312486-rumqopg0	486	44	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	486	45	syndrome	syndrome	NN
cord-312486-rumqopg0	486	46	in	in	IN
cord-312486-rumqopg0	486	47	children	child	NNS
cord-312486-rumqopg0	486	48	(	(	-LRB-
cord-312486-rumqopg0	486	49	MIS	MIS	NNP
cord-312486-rumqopg0	486	50	-	-	HYPH
cord-312486-rumqopg0	486	51	C	C	NNP
cord-312486-rumqopg0	486	52	)	)	-RRB-
cord-312486-rumqopg0	486	53	in	in	IN
cord-312486-rumqopg0	486	54	the	the	DT
cord-312486-rumqopg0	486	55	context	context	NN
cord-312486-rumqopg0	486	56	of	of	IN
cord-312486-rumqopg0	486	57	global	global	JJ
cord-312486-rumqopg0	486	58	SARS	SARS	NNP
cord-312486-rumqopg0	486	59	-	-	HYPH
cord-312486-rumqopg0	486	60	CoV-2	CoV-2	NNP
cord-312486-rumqopg0	486	61	pandemic	pandemic	NN
cord-312486-rumqopg0	486	62	Kawasaki	Kawasaki	NNP
cord-312486-rumqopg0	486	63	-	-	HYPH
cord-312486-rumqopg0	486	64	like	like	JJ
cord-312486-rumqopg0	486	65	multisystem	multisystem	JJ
cord-312486-rumqopg0	486	66	inflammatory	inflammatory	JJ
cord-312486-rumqopg0	486	67	syndrome	syndrome	NN
cord-312486-rumqopg0	486	68	in	in	IN
cord-312486-rumqopg0	486	69	children	child	NNS
cord-312486-rumqopg0	486	70	during	during	IN
cord-312486-rumqopg0	486	71	the	the	DT
cord-312486-rumqopg0	486	72	covid-19	covid-19	CD
cord-312486-rumqopg0	486	73	pandemic	pandemic	NN
cord-312486-rumqopg0	486	74	Long	long	JJ
cord-312486-rumqopg0	486	75	term	term	NN
cord-312486-rumqopg0	486	76	sequalae	sequalae	NNS
cord-312486-rumqopg0	486	77	of	of	IN
cord-312486-rumqopg0	486	78	SARS	SARS	NNP
cord-312486-rumqopg0	486	79	:	:	:
cord-312486-rumqopg0	486	80	physical	physical	JJ
cord-312486-rumqopg0	486	81	,	,	,
cord-312486-rumqopg0	486	82	neuropsychiatric	neuropsychiatric	JJ
cord-312486-rumqopg0	486	83	,	,	,
cord-312486-rumqopg0	486	84	and	and	CC
cord-312486-rumqopg0	486	85	quality	quality	NN
cord-312486-rumqopg0	486	86	-	-	HYPH
cord-312486-rumqopg0	486	87	of	of	IN
cord-312486-rumqopg0	486	88	-	-	HYPH
cord-312486-rumqopg0	486	89	life	life	NN
cord-312486-rumqopg0	486	90	assessment	assessment	NN
cord-312486-rumqopg0	486	91	On	on	IN
cord-312486-rumqopg0	486	92	the	the	DT
cord-312486-rumqopg0	486	93	Normal	normal	JJ
cord-312486-rumqopg0	486	94	and	and	CC
cord-312486-rumqopg0	486	95	the	the	DT
cord-312486-rumqopg0	486	96	Pathological	pathological	JJ
cord-312486-rumqopg0	487	1	The	the	DT
cord-312486-rumqopg0	487	2	triple	triple	JJ
cord-312486-rumqopg0	487	3	helix	helix	NN
cord-312486-rumqopg0	488	1	Some	some	DT
cord-312486-rumqopg0	488	2	savage	savage	NN
cord-312486-rumqopg0	488	3	cuts	cut	NNS
cord-312486-rumqopg0	488	4	in	in	IN
cord-312486-rumqopg0	488	5	defense	defense	NN
cord-312486-rumqopg0	489	1	I	-PRON-	PRP
cord-312486-rumqopg0	489	2	thank	thank	VBP
cord-312486-rumqopg0	489	3	Tamar	Tamar	NNP
cord-312486-rumqopg0	489	4	Jacob	Jacob	NNP
cord-312486-rumqopg0	489	5	-	-	HYPH
cord-312486-rumqopg0	489	6	Eliasi	Eliasi	NNP
cord-312486-rumqopg0	489	7	for	for	IN
cord-312486-rumqopg0	489	8	invaluable	invaluable	JJ
cord-312486-rumqopg0	489	9	help	help	NN
cord-312486-rumqopg0	489	10	with	with	IN
cord-312486-rumqopg0	489	11	editing	editing	NN
cord-312486-rumqopg0	489	12	and	and	CC
cord-312486-rumqopg0	489	13	proofreading	proofread	VBG
cord-312486-rumqopg0	489	14	the	the	DT
cord-312486-rumqopg0	489	15	manuscript	manuscript	NN
cord-312486-rumqopg0	489	16	.	.	.
cord-312486-rumqopg0	490	1	COJ	COJ	NNP
cord-312486-rumqopg0	490	2	is	be	VBZ
cord-312486-rumqopg0	490	3	funded	fund	VBN
cord-312486-rumqopg0	490	4	by	by	IN
cord-312486-rumqopg0	490	5	NIH	NIH	NNP
cord-312486-rumqopg0	490	6	grant	grant	NN
cord-312486-rumqopg0	490	7	R01AR072212	R01AR072212	NNP
cord-312486-rumqopg0	490	8	.	.	.