id	sid	tid	token	lemma	pos
cord-311730-189vax2m	1	1	key	key	JJ
cord-311730-189vax2m	1	2	:	:	:
cord-311730-189vax2m	1	3	cord-311730	cord-311730	NNP
cord-311730-189vax2m	1	4	-	-	HYPH
cord-311730-189vax2m	1	5	189vax2	189vax2	CD
cord-311730-189vax2m	1	6	m	m	CD
cord-311730-189vax2m	1	7	authors	author	NNS
cord-311730-189vax2m	1	8	:	:	:
cord-311730-189vax2m	1	9	Becker	Becker	NNP
cord-311730-189vax2m	1	10	,	,	,
cord-311730-189vax2m	1	11	Richard	Richard	NNP
cord-311730-189vax2m	1	12	C.	C.	NNP
cord-311730-189vax2m	1	13	title	title	NN
cord-311730-189vax2m	1	14	:	:	:
cord-311730-189vax2m	2	1	Covid-19	Covid-19	NNP
cord-311730-189vax2m	2	2	treatment	treatment	NN
cord-311730-189vax2m	2	3	update	update	NN
cord-311730-189vax2m	2	4	:	:	:
cord-311730-189vax2m	2	5	follow	follow	VB
cord-311730-189vax2m	2	6	the	the	DT
cord-311730-189vax2m	2	7	scientific	scientific	JJ
cord-311730-189vax2m	2	8	evidence	evidence	NN
cord-311730-189vax2m	2	9	date	date	NN
cord-311730-189vax2m	2	10	:	:	:
cord-311730-189vax2m	2	11	2020	2020	CD
cord-311730-189vax2m	2	12	-	-	HYPH
cord-311730-189vax2m	2	13	04	04	CD
cord-311730-189vax2m	2	14	-	-	HYPH
cord-311730-189vax2m	2	15	27	27	CD
cord-311730-189vax2m	2	16	journal	journal	NN
cord-311730-189vax2m	2	17	:	:	:
cord-311730-189vax2m	2	18	J	J	NNP
cord-311730-189vax2m	2	19	Thromb	Thromb	NNP
cord-311730-189vax2m	2	20	Thrombolysis	Thrombolysis	NNP
cord-311730-189vax2m	2	21	DOI	DOI	NNP
cord-311730-189vax2m	2	22	:	:	:
cord-311730-189vax2m	2	23	10.1007	10.1007	CD
cord-311730-189vax2m	2	24	/	/	SYM
cord-311730-189vax2m	2	25	s11239	s11239	CD
cord-311730-189vax2m	2	26	-	-	HYPH
cord-311730-189vax2m	2	27	020	020	CD
cord-311730-189vax2m	2	28	-	-	HYPH
cord-311730-189vax2m	2	29	02120	02120	CD
cord-311730-189vax2m	2	30	-	-	SYM
cord-311730-189vax2m	2	31	9	9	CD
cord-311730-189vax2m	2	32	sha	sha	NN
cord-311730-189vax2m	2	33	:	:	:
cord-311730-189vax2m	2	34	52a4643720cdc949e1277802ffbfb19dfc0ab6d2	52a4643720cdc949e1277802ffbfb19dfc0ab6d2	NNS
cord-311730-189vax2m	2	35	doc_id	doc_id	CD
cord-311730-189vax2m	2	36	:	:	:
cord-311730-189vax2m	2	37	311730	311730	CD
cord-311730-189vax2m	2	38	cord_uid	cord_uid	NNS
cord-311730-189vax2m	2	39	:	:	:
cord-311730-189vax2m	3	1	189vax2	189vax2	CD
cord-311730-189vax2m	3	2	m	m	NNP
cord-311730-189vax2m	3	3	nan	nan	NNP
cord-311730-189vax2m	4	1	There	there	EX
cord-311730-189vax2m	4	2	is	be	VBZ
cord-311730-189vax2m	4	3	not	not	RB
cord-311730-189vax2m	4	4	an	an	DT
cord-311730-189vax2m	4	5	FDA	FDA	NNP
cord-311730-189vax2m	4	6	-	-	HYPH
cord-311730-189vax2m	4	7	approved	approve	VBN
cord-311730-189vax2m	4	8	treatment	treatment	NN
cord-311730-189vax2m	4	9	for	for	IN
cord-311730-189vax2m	4	10	COVID-19	covid-19	NN
cord-311730-189vax2m	4	11	at	at	IN
cord-311730-189vax2m	4	12	this	this	DT
cord-311730-189vax2m	4	13	time	time	NN
cord-311730-189vax2m	4	14	;	;	:
cord-311730-189vax2m	4	15	however	however	RB
cord-311730-189vax2m	4	16	,	,	,
cord-311730-189vax2m	4	17	high	high	JJ
cord-311730-189vax2m	4	18	-	-	HYPH
cord-311730-189vax2m	4	19	level	level	NN
cord-311730-189vax2m	4	20	effort	effort	NN
cord-311730-189vax2m	4	21	and	and	CC
cord-311730-189vax2m	4	22	investigations	investigation	NNS
cord-311730-189vax2m	4	23	remain	remain	VBP
cord-311730-189vax2m	4	24	and	and	CC
cord-311730-189vax2m	4	25	are	be	VBP
cord-311730-189vax2m	4	26	in	in	IN
cord-311730-189vax2m	4	27	progress	progress	NN
cord-311730-189vax2m	4	28	,	,	,
cord-311730-189vax2m	4	29	respectively	respectively	RB
cord-311730-189vax2m	4	30	.	.	.
cord-311730-189vax2m	5	1	Taking	take	VBG
cord-311730-189vax2m	5	2	a	a	DT
cord-311730-189vax2m	5	3	SARS	SARS	NNP
cord-311730-189vax2m	5	4	-	-	HYPH
cord-311730-189vax2m	5	5	CoV-2	CoV-2	NNP
cord-311730-189vax2m	5	6	specific	specific	JJ
cord-311730-189vax2m	5	7	approach	approach	NN
cord-311730-189vax2m	5	8	to	to	IN
cord-311730-189vax2m	5	9	drug	drug	NN
cord-311730-189vax2m	5	10	development	development	NN
cord-311730-189vax2m	5	11	is	be	VBZ
cord-311730-189vax2m	5	12	logical	logical	JJ
cord-311730-189vax2m	5	13	and	and	CC
cord-311730-189vax2m	5	14	was	be	VBD
cord-311730-189vax2m	5	15	recently	recently	RB
cord-311730-189vax2m	5	16	summarized	summarize	VBN
cord-311730-189vax2m	5	17	by	by	IN
cord-311730-189vax2m	5	18	Kupferschmidt	Kupferschmidt	NNP
cord-311730-189vax2m	5	19	et	et	FW
cord-311730-189vax2m	5	20	al	al	NNP
cord-311730-189vax2m	5	21	.	.	.
cord-311730-189vax2m	6	1	[	[	-LRB-
cord-311730-189vax2m	6	2	3	3	CD
cord-311730-189vax2m	6	3	]	]	-RRB-
cord-311730-189vax2m	7	1	(	(	-LRB-
cord-311730-189vax2m	7	2	On	on	IN
cord-311730-189vax2m	7	3	March	March	NNP
cord-311730-189vax2m	7	4	28	28	CD
cord-311730-189vax2m	7	5	,	,	,
cord-311730-189vax2m	7	6	2020	2020	CD
cord-311730-189vax2m	7	7	the	the	DT
cord-311730-189vax2m	7	8	United	United	NNP
cord-311730-189vax2m	7	9	States	States	NNP
cord-311730-189vax2m	7	10	Food	Food	NNP
cord-311730-189vax2m	7	11	and	and	CC
cord-311730-189vax2m	7	12	Drug	Drug	NNP
cord-311730-189vax2m	7	13	Administration	Administration	NNP
cord-311730-189vax2m	7	14	(	(	-LRB-
cord-311730-189vax2m	7	15	FDA	FDA	NNP
cord-311730-189vax2m	7	16	issued	issue	VBD
cord-311730-189vax2m	7	17	)	)	-RRB-
cord-311730-189vax2m	7	18	an	an	DT
cord-311730-189vax2m	7	19	emergency	emergency	NN
cord-311730-189vax2m	7	20	use	use	NN
cord-311730-189vax2m	7	21	authorization	authorization	NN
cord-311730-189vax2m	7	22	(	(	-LRB-
cord-311730-189vax2m	7	23	EUA	EUA	NNP
cord-311730-189vax2m	7	24	)	)	-RRB-
cord-311730-189vax2m	7	25	permitting	permit	VBG
cord-311730-189vax2m	7	26	chloroquine	chloroquine	NN
cord-311730-189vax2m	7	27	phosphate	phosphate	NN
cord-311730-189vax2m	7	28	(	(	-LRB-
cord-311730-189vax2m	7	29	medical	medical	JJ
cord-311730-189vax2m	7	30	grade	grade	NN
cord-311730-189vax2m	7	31	)	)	-RRB-
cord-311730-189vax2m	7	32	and	and	CC
cord-311730-189vax2m	7	33	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	7	34	sulfate	sulfate	NN
cord-311730-189vax2m	7	35	to	to	TO
cord-311730-189vax2m	7	36	be	be	VB
cord-311730-189vax2m	7	37	added	add	VBN
cord-311730-189vax2m	7	38	to	to	IN
cord-311730-189vax2m	7	39	the	the	DT
cord-311730-189vax2m	7	40	strategic	strategic	JJ
cord-311730-189vax2m	7	41	national	national	JJ
cord-311730-189vax2m	7	42	stockpile	stockpile	NN
cord-311730-189vax2m	7	43	(	(	-LRB-
cord-311730-189vax2m	7	44	SNS	SNS	NNP
cord-311730-189vax2m	7	45	)	)	-RRB-
cord-311730-189vax2m	7	46	(	(	-LRB-
cord-311730-189vax2m	7	47	Fig	Fig	NNP
cord-311730-189vax2m	7	48	.	.	NNP
cord-311730-189vax2m	7	49	2	2	CD
cord-311730-189vax2m	7	50	)	)	-RRB-
cord-311730-189vax2m	7	51	.	.	.
cord-311730-189vax2m	8	1	The	the	DT
cord-311730-189vax2m	8	2	SNS	SNS	NNP
cord-311730-189vax2m	8	3	exists	exist	VBZ
cord-311730-189vax2m	8	4	under	under	IN
cord-311730-189vax2m	8	5	the	the	DT
cord-311730-189vax2m	8	6	authority	authority	NN
cord-311730-189vax2m	8	7	of	of	IN
cord-311730-189vax2m	8	8	the	the	DT
cord-311730-189vax2m	8	9	United	United	NNP
cord-311730-189vax2m	8	10	States	States	NNP
cord-311730-189vax2m	8	11	Department	Department	NNP
cord-311730-189vax2m	8	12	of	of	IN
cord-311730-189vax2m	8	13	Health	Health	NNP
cord-311730-189vax2m	8	14	and	and	CC
cord-311730-189vax2m	8	15	Human	Human	NNP
cord-311730-189vax2m	8	16	Services	Services	NNPS
cord-311730-189vax2m	8	17	(	(	-LRB-
cord-311730-189vax2m	8	18	HHS	HHS	NNP
cord-311730-189vax2m	8	19	)	)	-RRB-
cord-311730-189vax2m	8	20	and	and	CC
cord-311730-189vax2m	8	21	accepted	accept	VBD
cord-311730-189vax2m	8	22	30	30	CD
cord-311730-189vax2m	8	23	million	million	CD
cord-311730-189vax2m	8	24	doses	dose	NNS
cord-311730-189vax2m	8	25	of	of	IN
cord-311730-189vax2m	8	26	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	8	27	sulfate	sulfate	NN
cord-311730-189vax2m	8	28	donated	donate	VBN
cord-311730-189vax2m	8	29	by	by	IN
cord-311730-189vax2m	8	30	Sandoz	Sandoz	NNP
cord-311730-189vax2m	8	31	™	™	NN
cord-311730-189vax2m	8	32	,	,	,
cord-311730-189vax2m	8	33	the	the	DT
cord-311730-189vax2m	8	34	Novartis	Novartis	NNP
cord-311730-189vax2m	8	35	™	™	HYPH
cord-311730-189vax2m	8	36	generics	generic	NNS
cord-311730-189vax2m	8	37	and	and	CC
cord-311730-189vax2m	8	38	biosimilars	biosimilars	NNP
cord-311730-189vax2m	8	39	division	division	NN
cord-311730-189vax2m	8	40	,	,	,
cord-311730-189vax2m	8	41	and	and	CC
cord-311730-189vax2m	8	42	one	one	CD
cord-311730-189vax2m	8	43	million	million	CD
cord-311730-189vax2m	8	44	doses	dose	NNS
cord-311730-189vax2m	8	45	of	of	IN
cord-311730-189vax2m	8	46	chloroquine	chloroquine	NN
cord-311730-189vax2m	8	47	phosphate	phosphate	NN
cord-311730-189vax2m	8	48	donated	donate	VBN
cord-311730-189vax2m	8	49	by	by	IN
cord-311730-189vax2m	8	50	Bayer	Bayer	NNP
cord-311730-189vax2m	8	51	Pharmaceuticals	Pharmaceuticals	NNP
cord-311730-189vax2m	8	52	™	™	NN
cord-311730-189vax2m	8	53	for	for	IN
cord-311730-189vax2m	8	54	potential	potential	JJ
cord-311730-189vax2m	8	55	use	use	NN
cord-311730-189vax2m	8	56	in	in	IN
cord-311730-189vax2m	8	57	treating	treat	VBG
cord-311730-189vax2m	8	58	patients	patient	NNS
cord-311730-189vax2m	8	59	who	who	WP
cord-311730-189vax2m	8	60	were	be	VBD
cord-311730-189vax2m	8	61	hospitalized	hospitalize	VBN
cord-311730-189vax2m	8	62	with	with	IN
cord-311730-189vax2m	8	63	COVID-19	covid-19	CD
cord-311730-189vax2m	8	64	or	or	CC
cord-311730-189vax2m	8	65	for	for	IN
cord-311730-189vax2m	8	66	use	use	NN
cord-311730-189vax2m	8	67	in	in	IN
cord-311730-189vax2m	8	68	clinical	clinical	JJ
cord-311730-189vax2m	8	69	trials	trial	NNS
cord-311730-189vax2m	8	70	.	.	.
cord-311730-189vax2m	9	1	In	in	IN
cord-311730-189vax2m	9	2	addition	addition	NN
cord-311730-189vax2m	9	3	to	to	IN
cord-311730-189vax2m	9	4	the	the	DT
cord-311730-189vax2m	9	5	SNS	SNS	NNP
cord-311730-189vax2m	9	6	donations	donation	NNS
cord-311730-189vax2m	9	7	,	,	,
cord-311730-189vax2m	9	8	these	these	DT
cord-311730-189vax2m	9	9	companies	company	NNS
cord-311730-189vax2m	9	10	and	and	CC
cord-311730-189vax2m	9	11	potentially	potentially	RB
cord-311730-189vax2m	9	12	others	other	NNS
cord-311730-189vax2m	9	13	could	could	MD
cord-311730-189vax2m	9	14	offer	offer	VB
cord-311730-189vax2m	9	15	additional	additional	JJ
cord-311730-189vax2m	9	16	doses	dose	NNS
cord-311730-189vax2m	9	17	(	(	-LRB-
cord-311730-189vax2m	9	18	www	www	NN
cord-311730-189vax2m	9	19	.	.	.
cord-311730-189vax2m	10	1	fda.gov	fda.gov	NNP
cord-311730-189vax2m	10	2	)	)	-RRB-
cord-311730-189vax2m	10	3	.	.	.
cord-311730-189vax2m	11	1	There	there	EX
cord-311730-189vax2m	11	2	was	be	VBD
cord-311730-189vax2m	11	3	an	an	DT
cord-311730-189vax2m	11	4	expectation	expectation	NN
cord-311730-189vax2m	11	5	that	that	IN
cord-311730-189vax2m	11	6	companies	company	NNS
cord-311730-189vax2m	11	7	would	would	MD
cord-311730-189vax2m	11	8	increase	increase	VB
cord-311730-189vax2m	11	9	production	production	NN
cord-311730-189vax2m	11	10	for	for	IN
cord-311730-189vax2m	11	11	the	the	DT
cord-311730-189vax2m	11	12	commercial	commercial	JJ
cord-311730-189vax2m	11	13	market	market	NN
cord-311730-189vax2m	11	14	as	as	RB
cord-311730-189vax2m	11	15	well	well	RB
cord-311730-189vax2m	11	16	to	to	TO
cord-311730-189vax2m	11	17	avoid	avoid	VB
cord-311730-189vax2m	11	18	shortages	shortage	NNS
cord-311730-189vax2m	11	19	for	for	IN
cord-311730-189vax2m	11	20	patients	patient	NNS
cord-311730-189vax2m	11	21	with	with	IN
cord-311730-189vax2m	11	22	autoimmune	autoimmune	JJ
cord-311730-189vax2m	11	23	disease	disease	NN
cord-311730-189vax2m	11	24	who	who	WP
cord-311730-189vax2m	11	25	rely	rely	VBP
cord-311730-189vax2m	11	26	on	on	IN
cord-311730-189vax2m	11	27	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	11	28	sulfate	sulfate	NN
cord-311730-189vax2m	11	29	(	(	-LRB-
cord-311730-189vax2m	11	30	Plaquenil	Plaquenil	NNP
cord-311730-189vax2m	11	31	®	®	.
cord-311730-189vax2m	11	32	)	)	-RRB-
cord-311730-189vax2m	11	33	for	for	IN
cord-311730-189vax2m	11	34	routine	routine	JJ
cord-311730-189vax2m	11	35	treatment	treatment	NN
cord-311730-189vax2m	11	36	[	[	-LRB-
cord-311730-189vax2m	11	37	4	4	CD
cord-311730-189vax2m	11	38	]	]	-RRB-
cord-311730-189vax2m	11	39	.	.	.
cord-311730-189vax2m	12	1	The	the	DT
cord-311730-189vax2m	12	2	coordinated	coordinated	JJ
cord-311730-189vax2m	12	3	use	use	NN
cord-311730-189vax2m	12	4	of	of	IN
cord-311730-189vax2m	12	5	chloroquine	chloroquine	NN
cord-311730-189vax2m	12	6	phosphate	phosphate	NN
cord-311730-189vax2m	12	7	and	and	CC
cord-311730-189vax2m	12	8	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	12	9	sulfate	sulfate	NN
cord-311730-189vax2m	12	10	is	be	VBZ
cord-311730-189vax2m	12	11	governed	govern	VBN
cord-311730-189vax2m	12	12	by	by	IN
cord-311730-189vax2m	12	13	the	the	DT
cord-311730-189vax2m	12	14	HHS	HHS	NNP
cord-311730-189vax2m	12	15	office	office	NN
cord-311730-189vax2m	12	16	of	of	IN
cord-311730-189vax2m	12	17	the	the	DT
cord-311730-189vax2m	12	18	Assistant	Assistant	NNP
cord-311730-189vax2m	12	19	Secretary	Secretary	NNP
cord-311730-189vax2m	12	20	of	of	IN
cord-311730-189vax2m	12	21	Preparedness	Preparedness	NNP
cord-311730-189vax2m	12	22	and	and	CC
cord-311730-189vax2m	12	23	Response	Response	NNP
cord-311730-189vax2m	12	24	(	(	-LRB-
cord-311730-189vax2m	12	25	ASPR	ASPR	NNP
cord-311730-189vax2m	12	26	)	)	-RRB-
cord-311730-189vax2m	12	27	.	.	.
cord-311730-189vax2m	13	1	In	in	IN
cord-311730-189vax2m	13	2	turn	turn	NN
cord-311730-189vax2m	13	3	,	,	,
cord-311730-189vax2m	13	4	APSR	APSR	NNP
cord-311730-189vax2m	13	5	's	's	POS
cord-311730-189vax2m	13	6	Biomedical	Biomedical	NNP
cord-311730-189vax2m	13	7	Advanced	Advanced	NNP
cord-311730-189vax2m	13	8	Research	Research	NNP
cord-311730-189vax2m	13	9	and	and	CC
cord-311730-189vax2m	13	10	Development	Development	NNP
cord-311730-189vax2m	13	11	Authority	Authority	NNP
cord-311730-189vax2m	13	12	(	(	-LRB-
cord-311730-189vax2m	13	13	BARDA	BARDA	NNP
cord-311730-189vax2m	13	14	)	)	-RRB-
cord-311730-189vax2m	13	15	works	work	VBZ
cord-311730-189vax2m	13	16	collaboratively	collaboratively	RB
cord-311730-189vax2m	13	17	with	with	IN
cord-311730-189vax2m	13	18	the	the	DT
cord-311730-189vax2m	13	19	National	National	NNP
cord-311730-189vax2m	13	20	Institutes	Institutes	NNPS
cord-311730-189vax2m	13	21	of	of	IN
cord-311730-189vax2m	13	22	Health	Health	NNP
cord-311730-189vax2m	13	23	(	(	-LRB-
cord-311730-189vax2m	13	24	NIH	NIH	NNP
cord-311730-189vax2m	13	25	)	)	-RRB-
cord-311730-189vax2m	13	26	and	and	CC
cord-311730-189vax2m	13	27	FDA	FDA	NNP
cord-311730-189vax2m	13	28	to	to	TO
cord-311730-189vax2m	13	29	assure	assure	VB
cord-311730-189vax2m	13	30	safety	safety	NN
cord-311730-189vax2m	13	31	and	and	CC
cord-311730-189vax2m	13	32	the	the	DT
cord-311730-189vax2m	13	33	drugs	drug	NNS
cord-311730-189vax2m	13	34	appropriate	appropriate	JJ
cord-311730-189vax2m	13	35	use	use	NN
cord-311730-189vax2m	13	36	to	to	TO
cord-311730-189vax2m	13	37	include	include	VB
cord-311730-189vax2m	13	38	well	well	RB
cord-311730-189vax2m	13	39	-	-	HYPH
cord-311730-189vax2m	13	40	designed	design	VBN
cord-311730-189vax2m	13	41	clinical	clinical	JJ
cord-311730-189vax2m	13	42	trials	trial	NNS
cord-311730-189vax2m	13	43	(	(	-LRB-
cord-311730-189vax2m	13	44	Fig	Fig	NNP
cord-311730-189vax2m	13	45	.	.	.
cord-311730-189vax2m	13	46	3	3	CD
cord-311730-189vax2m	13	47	)	)	-RRB-
cord-311730-189vax2m	13	48	.	.	.
cord-311730-189vax2m	14	1	The	the	DT
cord-311730-189vax2m	14	2	EUA	EUA	NNP
cord-311730-189vax2m	14	3	grants	grant	NNS
cord-311730-189vax2m	14	4	permission	permission	NN
cord-311730-189vax2m	14	5	to	to	IN
cord-311730-189vax2m	14	6	BARDA	BARDA	NNP
cord-311730-189vax2m	14	7	allowing	allow	VBG
cord-311730-189vax2m	14	8	chloroquine	chloroquine	NN
cord-311730-189vax2m	14	9	phosphate	phosphate	NN
cord-311730-189vax2m	14	10	and	and	CC
cord-311730-189vax2m	14	11	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	14	12	sulfate	sulfate	NN
cord-311730-189vax2m	14	13	to	to	TO
cord-311730-189vax2m	14	14	be	be	VB
cord-311730-189vax2m	14	15	distributed	distribute	VBN
cord-311730-189vax2m	14	16	and	and	CC
cord-311730-189vax2m	14	17	prescribed	prescribe	VBN
cord-311730-189vax2m	14	18	by	by	IN
cord-311730-189vax2m	14	19	physicians	physician	NNS
cord-311730-189vax2m	14	20	to	to	IN
cord-311730-189vax2m	14	21	hospitalized	hospitalize	VBN
cord-311730-189vax2m	14	22	teen	teen	NN
cord-311730-189vax2m	14	23	and	and	CC
cord-311730-189vax2m	14	24	adult	adult	NN
cord-311730-189vax2m	14	25	patients	patient	NNS
cord-311730-189vax2m	14	26	with	with	IN
cord-311730-189vax2m	14	27	Covid-19	Covid-19	NNP
cord-311730-189vax2m	14	28	,	,	,
cord-311730-189vax2m	14	29	when	when	WRB
cord-311730-189vax2m	14	30	deemed	deem	VBN
cord-311730-189vax2m	14	31	appropriate	appropriate	JJ
cord-311730-189vax2m	14	32	,	,	,
cord-311730-189vax2m	14	33	if	if	IN
cord-311730-189vax2m	14	34	a	a	DT
cord-311730-189vax2m	14	35	clinical	clinical	JJ
cord-311730-189vax2m	14	36	trial	trial	NN
cord-311730-189vax2m	14	37	is	be	VBZ
cord-311730-189vax2m	14	38	either	either	CC
cord-311730-189vax2m	14	39	not	not	RB
cord-311730-189vax2m	14	40	available	available	JJ
cord-311730-189vax2m	14	41	or	or	CC
cord-311730-189vax2m	14	42	feasible	feasible	JJ
cord-311730-189vax2m	14	43	.	.	.
cord-311730-189vax2m	15	1	The	the	DT
cord-311730-189vax2m	15	2	EUA	EUA	NNP
cord-311730-189vax2m	15	3	mandates	mandate	NNS
cord-311730-189vax2m	15	4	that	that	WDT
cord-311730-189vax2m	15	5	fact	fact	NN
cord-311730-189vax2m	15	6	sheets	sheet	NNS
cord-311730-189vax2m	15	7	summarizing	summarize	VBG
cord-311730-189vax2m	15	8	important	important	JJ
cord-311730-189vax2m	15	9	information	information	NN
cord-311730-189vax2m	15	10	about	about	IN
cord-311730-189vax2m	15	11	the	the	DT
cord-311730-189vax2m	15	12	drugs	drug	NNS
cord-311730-189vax2m	15	13	and	and	CC
cord-311730-189vax2m	15	14	their	-PRON-	PRP$
cord-311730-189vax2m	15	15	administration	administration	NN
cord-311730-189vax2m	15	16	are	be	VBP
cord-311730-189vax2m	15	17	made	make	VBN
cord-311730-189vax2m	15	18	availability	availability	NN
cord-311730-189vax2m	15	19	to	to	IN
cord-311730-189vax2m	15	20	patients	patient	NNS
cord-311730-189vax2m	15	21	and	and	CC
cord-311730-189vax2m	15	22	prescribers	prescriber	NNS
cord-311730-189vax2m	15	23	,	,	,
cord-311730-189vax2m	15	24	including	include	VBG
cord-311730-189vax2m	15	25	potential	potential	JJ
cord-311730-189vax2m	15	26	risk	risk	NN
cord-311730-189vax2m	15	27	and	and	CC
cord-311730-189vax2m	15	28	drug	drug	NN
cord-311730-189vax2m	15	29	interactions	interaction	NNS
cord-311730-189vax2m	15	30	.	.	.
cord-311730-189vax2m	16	1	Drug	drug	NN
cord-311730-189vax2m	16	2	shipments	shipment	NNS
cord-311730-189vax2m	16	3	to	to	IN
cord-311730-189vax2m	16	4	individual	individual	JJ
cord-311730-189vax2m	16	5	states	state	NNS
cord-311730-189vax2m	16	6	is	be	VBZ
cord-311730-189vax2m	16	7	overseen	oversee	VBN
cord-311730-189vax2m	16	8	by	by	IN
cord-311730-189vax2m	16	9	the	the	DT
cord-311730-189vax2m	16	10	Federal	Federal	NNP
cord-311730-189vax2m	16	11	Emergency	Emergency	NNP
cord-311730-189vax2m	16	12	Management	Management	NNP
cord-311730-189vax2m	16	13	Agency	Agency	NNP
cord-311730-189vax2m	16	14	(	(	-LRB-
cord-311730-189vax2m	16	15	FEMA	FEMA	NNP
cord-311730-189vax2m	16	16	)	)	-RRB-
cord-311730-189vax2m	16	17	who	who	WP
cord-311730-189vax2m	16	18	works	work	VBZ
cord-311730-189vax2m	16	19	closely	closely	RB
cord-311730-189vax2m	16	20	with	with	IN
cord-311730-189vax2m	16	21	the	the	DT
cord-311730-189vax2m	16	22	Department	Department	NNP
cord-311730-189vax2m	16	23	of	of	IN
cord-311730-189vax2m	16	24	State	State	NNP
cord-311730-189vax2m	16	25	and	and	CC
cord-311730-189vax2m	16	26	Department	Department	NNP
cord-311730-189vax2m	16	27	of	of	IN
cord-311730-189vax2m	16	28	Homeland	Homeland	NNP
cord-311730-189vax2m	16	29	Security	Security	NNP
cord-311730-189vax2m	16	30	to	to	TO
cord-311730-189vax2m	16	31	secure	secure	VB
cord-311730-189vax2m	16	32	donated	donate	VBN
cord-311730-189vax2m	16	33	shipments	shipment	NNS
cord-311730-189vax2m	16	34	.	.	.
cord-311730-189vax2m	17	1	What	what	WP
cord-311730-189vax2m	17	2	is	be	VBZ
cord-311730-189vax2m	17	3	chloroquine	chloroquine	NN
cord-311730-189vax2m	17	4	,	,	,
cord-311730-189vax2m	17	5	how	how	WRB
cord-311730-189vax2m	17	6	does	do	VBZ
cord-311730-189vax2m	17	7	it	-PRON-	PRP
cord-311730-189vax2m	17	8	work	work	VB
cord-311730-189vax2m	18	1	and	and	CC
cord-311730-189vax2m	18	2	why	why	WRB
cord-311730-189vax2m	18	3	might	may	MD
cord-311730-189vax2m	18	4	it	-PRON-	PRP
cord-311730-189vax2m	18	5	be	be	VB
cord-311730-189vax2m	18	6	effective	effective	JJ
cord-311730-189vax2m	18	7	in	in	IN
cord-311730-189vax2m	18	8	the	the	DT
cord-311730-189vax2m	18	9	treatment	treatment	NN
cord-311730-189vax2m	18	10	of	of	IN
cord-311730-189vax2m	18	11	COVID-19	COVID-19	NNP
cord-311730-189vax2m	18	12	?	?	.
cord-311730-189vax2m	19	1	Chloroquine	Chloroquine	NNP
cord-311730-189vax2m	19	2	was	be	VBD
cord-311730-189vax2m	19	3	discovered	discover	VBN
cord-311730-189vax2m	19	4	in	in	IN
cord-311730-189vax2m	19	5	the	the	DT
cord-311730-189vax2m	19	6	early	early	JJ
cord-311730-189vax2m	19	7	1930′s	1930′s	CD
cord-311730-189vax2m	19	8	by	by	IN
cord-311730-189vax2m	19	9	Hans	Hans	NNP
cord-311730-189vax2m	19	10	Andersag	Andersag	NNP
cord-311730-189vax2m	19	11	,	,	,
cord-311730-189vax2m	19	12	a	a	DT
cord-311730-189vax2m	19	13	scientists	scientist	NNS
cord-311730-189vax2m	19	14	working	work	VBG
cord-311730-189vax2m	19	15	for	for	IN
cord-311730-189vax2m	19	16	Bayer	Bayer	NNP
cord-311730-189vax2m	19	17	AG	AG	NNP
cord-311730-189vax2m	19	18	™	™	NN
cord-311730-189vax2m	19	19	on	on	IN
cord-311730-189vax2m	19	20	compounds	compound	NNS
cord-311730-189vax2m	19	21	with	with	IN
cord-311730-189vax2m	19	22	anti	anti	JJ
cord-311730-189vax2m	19	23	-	-	JJ
cord-311730-189vax2m	19	24	malarial	malarial	JJ
cord-311730-189vax2m	19	25	properties	property	NNS
cord-311730-189vax2m	19	26	.	.	.
cord-311730-189vax2m	20	1	It	-PRON-	PRP
cord-311730-189vax2m	20	2	is	be	VBZ
cord-311730-189vax2m	20	3	a	a	DT
cord-311730-189vax2m	20	4	4-aminoquinoline	4-aminoquinoline	CD
cord-311730-189vax2m	20	5	compound	compound	NN
cord-311730-189vax2m	20	6	taken	take	VBN
cord-311730-189vax2m	20	7	by	by	IN
cord-311730-189vax2m	20	8	mouth	mouth	NN
cord-311730-189vax2m	20	9	and	and	CC
cord-311730-189vax2m	20	10	has	have	VBZ
cord-311730-189vax2m	20	11	a	a	DT
cord-311730-189vax2m	20	12	long	long	JJ
cord-311730-189vax2m	20	13	track	track	NN
cord-311730-189vax2m	20	14	record	record	NN
cord-311730-189vax2m	20	15	of	of	IN
cord-311730-189vax2m	20	16	mass	mass	NNP
cord-311730-189vax2m	20	17	administration	administration	NNP
cord-311730-189vax2m	20	18	for	for	IN
cord-311730-189vax2m	20	19	the	the	DT
cord-311730-189vax2m	20	20	prevention	prevention	NN
cord-311730-189vax2m	20	21	of	of	IN
cord-311730-189vax2m	20	22	malaria	malaria	NN
cord-311730-189vax2m	20	23	to	to	TO
cord-311730-189vax2m	20	24	include	include	VB
cord-311730-189vax2m	20	25	plasmodium	plasmodium	NN
cord-311730-189vax2m	20	26	vivax	vivax	NN
cord-311730-189vax2m	20	27	,	,	,
cord-311730-189vax2m	20	28	plasmodium	plasmodium	NN
cord-311730-189vax2m	20	29	ovale	ovale	NN
cord-311730-189vax2m	20	30	and	and	CC
cord-311730-189vax2m	20	31	plasmodium	plasmodium	NN
cord-311730-189vax2m	20	32	malariae	malariae	NNP
cord-311730-189vax2m	20	33	.	.	.
cord-311730-189vax2m	21	1	It	-PRON-	PRP
cord-311730-189vax2m	21	2	is	be	VBZ
cord-311730-189vax2m	21	3	typically	typically	RB
cord-311730-189vax2m	21	4	not	not	RB
cord-311730-189vax2m	21	5	used	use	VBN
cord-311730-189vax2m	21	6	for	for	IN
cord-311730-189vax2m	21	7	plasmodium	plasmodium	NN
cord-311730-189vax2m	21	8	falciparum	falciparum	NN
cord-311730-189vax2m	21	9	given	give	VBN
cord-311730-189vax2m	21	10	well	well	RB
cord-311730-189vax2m	21	11	-	-	HYPH
cord-311730-189vax2m	21	12	documented	document	VBN
cord-311730-189vax2m	21	13	resistance	resistance	NN
cord-311730-189vax2m	21	14	[	[	-LRB-
cord-311730-189vax2m	21	15	5	5	CD
cord-311730-189vax2m	21	16	]	]	-RRB-
cord-311730-189vax2m	21	17	.	.	.
cord-311730-189vax2m	22	1	Chloroquine	Chloroquine	NNP
cord-311730-189vax2m	22	2	is	be	VBZ
cord-311730-189vax2m	22	3	absorbed	absorb	VBN
cord-311730-189vax2m	22	4	rapidly	rapidly	RB
cord-311730-189vax2m	22	5	and	and	CC
cord-311730-189vax2m	22	6	has	have	VBZ
cord-311730-189vax2m	22	7	a	a	DT
cord-311730-189vax2m	22	8	wide	wide	JJ
cord-311730-189vax2m	22	9	volume	volume	NN
cord-311730-189vax2m	22	10	of	of	IN
cord-311730-189vax2m	22	11	distribution	distribution	NN
cord-311730-189vax2m	22	12	and	and	CC
cord-311730-189vax2m	22	13	undergoes	undergo	VBZ
cord-311730-189vax2m	22	14	hepatic	hepatic	JJ
cord-311730-189vax2m	22	15	metabolism	metabolism	NN
cord-311730-189vax2m	22	16	giving	give	VBG
cord-311730-189vax2m	22	17	rise	rise	NN
cord-311730-189vax2m	22	18	to	to	IN
cord-311730-189vax2m	22	19	its	-PRON-	PRP$
cord-311730-189vax2m	22	20	primary	primary	JJ
cord-311730-189vax2m	22	21	metabolite	metabolite	JJ
cord-311730-189vax2m	22	22	desethylchloroquine	desethylchloroquine	NN
cord-311730-189vax2m	22	23	.	.	.
cord-311730-189vax2m	23	1	Approximately	approximately	RB
cord-311730-189vax2m	23	2	,	,	,
cord-311730-189vax2m	23	3	50	50	CD
cord-311730-189vax2m	23	4	%	%	NN
cord-311730-189vax2m	23	5	of	of	IN
cord-311730-189vax2m	23	6	the	the	DT
cord-311730-189vax2m	23	7	drug	drug	NN
cord-311730-189vax2m	23	8	is	be	VBZ
cord-311730-189vax2m	23	9	excreted	excrete	VBN
cord-311730-189vax2m	23	10	unchanged	unchanged	JJ
cord-311730-189vax2m	23	11	in	in	IN
cord-311730-189vax2m	23	12	the	the	DT
cord-311730-189vax2m	23	13	urine	urine	NN
cord-311730-189vax2m	23	14	.	.	.
cord-311730-189vax2m	24	1	Chloroquine	chloroquine	NN
cord-311730-189vax2m	24	2	accumulates	accumulate	VBZ
cord-311730-189vax2m	24	3	within	within	IN
cord-311730-189vax2m	24	4	lysosomes	lysosome	NNS
cord-311730-189vax2m	24	5	where	where	WRB
cord-311730-189vax2m	24	6	it	-PRON-	PRP
cord-311730-189vax2m	24	7	alters	alter	VBZ
cord-311730-189vax2m	24	8	cellular	cellular	JJ
cord-311730-189vax2m	24	9	pH	ph	NN
cord-311730-189vax2m	24	10	and	and	CC
cord-311730-189vax2m	24	11	is	be	VBZ
cord-311730-189vax2m	24	12	stored	store	VBN
cord-311730-189vax2m	24	13	in	in	IN
cord-311730-189vax2m	24	14	a	a	DT
cord-311730-189vax2m	24	15	protonated	protonated	JJ
cord-311730-189vax2m	24	16	form	form	NN
cord-311730-189vax2m	24	17	.	.	.
cord-311730-189vax2m	25	1	The	the	DT
cord-311730-189vax2m	25	2	antiviral	antiviral	JJ
cord-311730-189vax2m	25	3	effect	effect	NN
cord-311730-189vax2m	25	4	is	be	VBZ
cord-311730-189vax2m	25	5	believed	believe	VBN
cord-311730-189vax2m	25	6	to	to	TO
cord-311730-189vax2m	25	7	be	be	VB
cord-311730-189vax2m	25	8	from	from	IN
cord-311730-189vax2m	25	9	chloroquine	chloroquine	NN
cord-311730-189vax2m	25	10	's	's	POS
cord-311730-189vax2m	25	11	ability	ability	NN
cord-311730-189vax2m	25	12	to	to	TO
cord-311730-189vax2m	25	13	increase	increase	VB
cord-311730-189vax2m	25	14	endosomal	endosomal	NNP
cord-311730-189vax2m	25	15	and	and	CC
cord-311730-189vax2m	25	16	lysosomal	lysosomal	JJ
cord-311730-189vax2m	26	1	pH	pH	NNP
cord-311730-189vax2m	26	2	thereby	thereby	RB
cord-311730-189vax2m	26	3	attenuating	attenuate	VBG
cord-311730-189vax2m	26	4	the	the	DT
cord-311730-189vax2m	26	5	ability	ability	NN
cord-311730-189vax2m	26	6	of	of	IN
cord-311730-189vax2m	26	7	the	the	DT
cord-311730-189vax2m	26	8	virus	virus	NN
cord-311730-189vax2m	26	9	to	to	TO
cord-311730-189vax2m	26	10	release	release	VB
cord-311730-189vax2m	26	11	its	-PRON-	PRP$
cord-311730-189vax2m	26	12	genetic	genetic	JJ
cord-311730-189vax2m	26	13	material	material	NN
cord-311730-189vax2m	26	14	into	into	IN
cord-311730-189vax2m	26	15	the	the	DT
cord-311730-189vax2m	26	16	cell	cell	NN
cord-311730-189vax2m	26	17	and	and	CC
cord-311730-189vax2m	26	18	replicate	replicate	VB
cord-311730-189vax2m	26	19	.	.	.
cord-311730-189vax2m	27	1	The	the	DT
cord-311730-189vax2m	27	2	drug	drug	NN
cord-311730-189vax2m	27	3	also	also	RB
cord-311730-189vax2m	27	4	inhibits	inhibit	VBZ
cord-311730-189vax2m	27	5	important	important	JJ
cord-311730-189vax2m	27	6	post	post	JJ
cord-311730-189vax2m	27	7	-	-	JJ
cord-311730-189vax2m	27	8	translational	translational	JJ
cord-311730-189vax2m	27	9	steps	step	NNS
cord-311730-189vax2m	27	10	in	in	IN
cord-311730-189vax2m	27	11	newly	newly	RB
cord-311730-189vax2m	27	12	formed	form	VBN
cord-311730-189vax2m	27	13	proteins	protein	NNS
cord-311730-189vax2m	27	14	,	,	,
cord-311730-189vax2m	27	15	acts	act	VBZ
cord-311730-189vax2m	27	16	as	as	IN
cord-311730-189vax2m	27	17	a	a	DT
cord-311730-189vax2m	27	18	zinc	zinc	NN
cord-311730-189vax2m	27	19	ionophore	ionophore	NN
cord-311730-189vax2m	27	20	that	that	WDT
cord-311730-189vax2m	27	21	increases	increase	VBZ
cord-311730-189vax2m	27	22	intracellular	intracellular	JJ
cord-311730-189vax2m	27	23	zinc	zinc	NN
cord-311730-189vax2m	27	24	concentration	concentration	NN
cord-311730-189vax2m	27	25	and	and	CC
cord-311730-189vax2m	27	26	inhibits	inhibit	VBZ
cord-311730-189vax2m	27	27	RNAdependent	rnadependent	NN
cord-311730-189vax2m	27	28	polymerases	polymerase	NNS
cord-311730-189vax2m	27	29	,	,	,
cord-311730-189vax2m	27	30	decreases	decrease	VBZ
cord-311730-189vax2m	27	31	endosomal	endosomal	NNP
cord-311730-189vax2m	27	32	release	release	NN
cord-311730-189vax2m	27	33	of	of	IN
cord-311730-189vax2m	27	34	iron	iron	NN
cord-311730-189vax2m	27	35	required	require	VBN
cord-311730-189vax2m	27	36	for	for	IN
cord-311730-189vax2m	27	37	the	the	DT
cord-311730-189vax2m	27	38	replication	replication	NN
cord-311730-189vax2m	27	39	of	of	IN
cord-311730-189vax2m	27	40	DNA	dna	NN
cord-311730-189vax2m	27	41	and	and	CC
cord-311730-189vax2m	27	42	inhibits	inhibit	VBZ
cord-311730-189vax2m	27	43	glycosylation	glycosylation	NN
cord-311730-189vax2m	27	44	of	of	IN
cord-311730-189vax2m	27	45	envelope	envelope	NN
cord-311730-189vax2m	27	46	glycoproteins	glycoprotein	NNS
cord-311730-189vax2m	27	47	(	(	-LRB-
cord-311730-189vax2m	27	48	reviewed	review	VBN
cord-311730-189vax2m	27	49	in	in	IN
cord-311730-189vax2m	27	50	Savarino	Savarino	NNP
cord-311730-189vax2m	27	51	[	[	-LRB-
cord-311730-189vax2m	27	52	6	6	CD
cord-311730-189vax2m	27	53	]	]	-RRB-
cord-311730-189vax2m	27	54	)	)	-RRB-
cord-311730-189vax2m	27	55	.	.	.
cord-311730-189vax2m	28	1	There	there	EX
cord-311730-189vax2m	28	2	has	have	VBZ
cord-311730-189vax2m	28	3	been	be	VBN
cord-311730-189vax2m	28	4	interest	interest	NN
cord-311730-189vax2m	28	5	in	in	IN
cord-311730-189vax2m	28	6	the	the	DT
cord-311730-189vax2m	28	7	potential	potential	JJ
cord-311730-189vax2m	28	8	antithrombotic	antithrombotic	JJ
cord-311730-189vax2m	28	9	effects	effect	NNS
cord-311730-189vax2m	28	10	of	of	IN
cord-311730-189vax2m	28	11	chloroquine	chloroquine	NN
cord-311730-189vax2m	28	12	.	.	.
cord-311730-189vax2m	29	1	While	while	IN
cord-311730-189vax2m	29	2	the	the	DT
cord-311730-189vax2m	29	3	contribution	contribution	NN
cord-311730-189vax2m	29	4	to	to	IN
cord-311730-189vax2m	29	5	its	-PRON-	PRP$
cord-311730-189vax2m	29	6	overall	overall	JJ
cord-311730-189vax2m	29	7	benefit	benefit	NN
cord-311730-189vax2m	29	8	may	may	MD
cord-311730-189vax2m	29	9	be	be	VB
cord-311730-189vax2m	29	10	modest	modest	JJ
cord-311730-189vax2m	29	11	and	and	CC
cord-311730-189vax2m	29	12	largely	largely	RB
cord-311730-189vax2m	29	13	unknown	unknown	JJ
cord-311730-189vax2m	29	14	in	in	IN
cord-311730-189vax2m	29	15	patients	patient	NNS
cord-311730-189vax2m	29	16	with	with	IN
cord-311730-189vax2m	29	17	Covid-19	Covid-19	NNP
cord-311730-189vax2m	29	18	,	,	,
cord-311730-189vax2m	29	19	chloroquine	chloroquine	NN
cord-311730-189vax2m	29	20	reduces	reduce	VBZ
cord-311730-189vax2m	29	21	neutrophil	neutrophil	NN
cord-311730-189vax2m	29	22	extracellular	extracellular	JJ
cord-311730-189vax2m	29	23	trap	trap	NN
cord-311730-189vax2m	29	24	(	(	-LRB-
cord-311730-189vax2m	29	25	NET	net	NN
cord-311730-189vax2m	29	26	)	)	-RRB-
cord-311730-189vax2m	29	27	formation	formation	NN
cord-311730-189vax2m	29	28	,	,	,
cord-311730-189vax2m	29	29	platelet	platelet	NN
cord-311730-189vax2m	29	30	aggregation	aggregation	NN
cord-311730-189vax2m	29	31	and	and	CC
cord-311730-189vax2m	29	32	circulating	circulate	VBG
cord-311730-189vax2m	29	33	tissue	tissue	NN
cord-311730-189vax2m	29	34	factor	factor	NN
cord-311730-189vax2m	29	35	in	in	IN
cord-311730-189vax2m	29	36	mice	mouse	NNS
cord-311730-189vax2m	29	37	[	[	-LRB-
cord-311730-189vax2m	29	38	7	7	CD
cord-311730-189vax2m	29	39	]	]	-RRB-
cord-311730-189vax2m	29	40	.	.	.
cord-311730-189vax2m	30	1	Chloroquine	Chloroquine	NNP
cord-311730-189vax2m	30	2	has	have	VBZ
cord-311730-189vax2m	30	3	been	be	VBN
cord-311730-189vax2m	30	4	shown	show	VBN
cord-311730-189vax2m	30	5	to	to	TO
cord-311730-189vax2m	30	6	differentially	differentially	RB
cord-311730-189vax2m	30	7	modulate	modulate	VB
cord-311730-189vax2m	30	8	coronary	coronary	JJ
cord-311730-189vax2m	30	9	arterial	arterial	JJ
cord-311730-189vax2m	30	10	vasodilation	vasodilation	NN
cord-311730-189vax2m	30	11	in	in	IN
cord-311730-189vax2m	30	12	diabetic	diabetic	JJ
cord-311730-189vax2m	30	13	mice	mouse	NNS
cord-311730-189vax2m	30	14	[	[	-LRB-
cord-311730-189vax2m	30	15	8	8	CD
cord-311730-189vax2m	30	16	]	]	-RRB-
cord-311730-189vax2m	30	17	.	.	.
cord-311730-189vax2m	31	1	In	in	IN
cord-311730-189vax2m	31	2	humans	human	NNS
cord-311730-189vax2m	31	3	,	,	,
cord-311730-189vax2m	31	4	it	-PRON-	PRP
cord-311730-189vax2m	31	5	decreases	decrease	VBZ
cord-311730-189vax2m	31	6	nitric	nitric	NN
cord-311730-189vax2m	31	7	oxide	oxide	NN
cord-311730-189vax2m	31	8	production	production	NN
cord-311730-189vax2m	31	9	in	in	IN
cord-311730-189vax2m	31	10	coronary	coronary	JJ
cord-311730-189vax2m	31	11	artery	artery	NN
cord-311730-189vax2m	31	12	endothelial	endothelial	JJ
cord-311730-189vax2m	31	13	cells	cell	NNS
cord-311730-189vax2m	31	14	.	.	.
cord-311730-189vax2m	32	1	The	the	DT
cord-311730-189vax2m	32	2	potential	potential	JJ
cord-311730-189vax2m	32	3	clinical	clinical	JJ
cord-311730-189vax2m	32	4	impact	impact	NN
cord-311730-189vax2m	32	5	in	in	IN
cord-311730-189vax2m	32	6	Fig	Fig	NNP
cord-311730-189vax2m	32	7	.	.	.
cord-311730-189vax2m	33	1	1	1	LS
cord-311730-189vax2m	34	1	Targeted	target	VBN
cord-311730-189vax2m	34	2	approach	approach	NN
cord-311730-189vax2m	34	3	to	to	IN
cord-311730-189vax2m	34	4	drug	drug	NN
cord-311730-189vax2m	34	5	development	development	NN
cord-311730-189vax2m	34	6	for	for	IN
cord-311730-189vax2m	34	7	SARS	SARS	NNP
cord-311730-189vax2m	34	8	-	-	HYPH
cord-311730-189vax2m	34	9	CoV-2	CoV-2	NNP
cord-311730-189vax2m	34	10	.	.	.
cord-311730-189vax2m	35	1	The	the	DT
cord-311730-189vax2m	35	2	lines	line	NNS
cord-311730-189vax2m	35	3	of	of	IN
cord-311730-189vax2m	35	4	attack	attack	NN
cord-311730-189vax2m	35	5	against	against	IN
cord-311730-189vax2m	35	6	SARS	SARS	NNP
cord-311730-189vax2m	35	7	-	-	HYPH
cord-311730-189vax2m	35	8	CoV-2	CoV-2	NNP
cord-311730-189vax2m	35	9	,	,	,
cord-311730-189vax2m	35	10	numbered	number	VBD
cord-311730-189vax2m	35	11	1	1	CD
cord-311730-189vax2m	35	12	-	-	SYM
cord-311730-189vax2m	35	13	6	6	CD
cord-311730-189vax2m	35	14	,	,	,
cord-311730-189vax2m	35	15	include	include	VBP
cord-311730-189vax2m	35	16	inhibition	inhibition	NN
cord-311730-189vax2m	35	17	of	of	IN
cord-311730-189vax2m	35	18	:	:	:
cord-311730-189vax2m	35	19	(	(	-LRB-
cord-311730-189vax2m	35	20	1	1	LS
cord-311730-189vax2m	35	21	)	)	-RRB-
cord-311730-189vax2m	35	22	fusion	fusion	NN
cord-311730-189vax2m	35	23	;	;	,
cord-311730-189vax2m	35	24	(	(	-LRB-
cord-311730-189vax2m	35	25	2	2	LS
cord-311730-189vax2m	35	26	)	)	-RRB-
cord-311730-189vax2m	35	27	translation	translation	NN
cord-311730-189vax2m	35	28	;	;	,
cord-311730-189vax2m	35	29	(	(	-LRB-
cord-311730-189vax2m	35	30	3	3	LS
cord-311730-189vax2m	35	31	)	)	-RRB-
cord-311730-189vax2m	35	32	proteolysis	proteolysis	NN
cord-311730-189vax2m	35	33	;	;	:
cord-311730-189vax2m	35	34	(	(	-LRB-
cord-311730-189vax2m	35	35	4	4	LS
cord-311730-189vax2m	35	36	)	)	-RRB-
cord-311730-189vax2m	35	37	translation	translation	NN
cord-311730-189vax2m	35	38	and	and	CC
cord-311730-189vax2m	35	39	RNA	RNA	NNP
cord-311730-189vax2m	35	40	replication	replication	NN
cord-311730-189vax2m	35	41	;	;	,
cord-311730-189vax2m	35	42	(	(	-LRB-
cord-311730-189vax2m	35	43	5	5	LS
cord-311730-189vax2m	35	44	)	)	-RRB-
cord-311730-189vax2m	35	45	packaging	packaging	NN
cord-311730-189vax2m	35	46	and	and	CC
cord-311730-189vax2m	35	47	;	;	,
cord-311730-189vax2m	35	48	(	(	-LRB-
cord-311730-189vax2m	35	49	6	6	LS
cord-311730-189vax2m	35	50	)	)	-RRB-
cord-311730-189vax2m	35	51	virion	virion	NN
cord-311730-189vax2m	35	52	release	release	NN
cord-311730-189vax2m	35	53	.	.	.
cord-311730-189vax2m	36	1	From	from	IN
cord-311730-189vax2m	36	2	Kupferschmidt	Kupferschmidt	NNP
cord-311730-189vax2m	36	3	and	and	CC
cord-311730-189vax2m	36	4	Cohen	Cohen	NNP
cord-311730-189vax2m	36	5	[	[	-LRB-
cord-311730-189vax2m	36	6	3	3	CD
cord-311730-189vax2m	36	7	]	]	-RRB-
cord-311730-189vax2m	36	8	.	.	.
cord-311730-189vax2m	37	1	With	with	IN
cord-311730-189vax2m	37	2	permission	permission	NN
cord-311730-189vax2m	37	3	patients	patient	NNS
cord-311730-189vax2m	37	4	with	with	IN
cord-311730-189vax2m	37	5	coronary	coronary	JJ
cord-311730-189vax2m	37	6	artery	artery	NN
cord-311730-189vax2m	37	7	disease	disease	NN
cord-311730-189vax2m	37	8	is	be	VBZ
cord-311730-189vax2m	37	9	unknown	unknown	JJ
cord-311730-189vax2m	37	10	.	.	.
cord-311730-189vax2m	38	1	Chloroquine	Chloroquine	NNP
cord-311730-189vax2m	38	2	has	have	VBZ
cord-311730-189vax2m	38	3	been	be	VBN
cord-311730-189vax2m	38	4	shown	show	VBN
cord-311730-189vax2m	38	5	in	in	IN
cord-311730-189vax2m	38	6	animal	animal	NN
cord-311730-189vax2m	38	7	models	model	NNS
cord-311730-189vax2m	38	8	to	to	TO
cord-311730-189vax2m	38	9	inhibit	inhibit	VB
cord-311730-189vax2m	38	10	autophagy	autophagy	NN
cord-311730-189vax2m	38	11	with	with	IN
cord-311730-189vax2m	38	12	a	a	DT
cord-311730-189vax2m	38	13	resulting	result	VBG
cord-311730-189vax2m	38	14	improvement	improvement	NN
cord-311730-189vax2m	38	15	in	in	IN
cord-311730-189vax2m	38	16	diastolic	diastolic	JJ
cord-311730-189vax2m	38	17	performance	performance	NN
cord-311730-189vax2m	38	18	in	in	IN
cord-311730-189vax2m	38	19	diabetic	diabetic	JJ
cord-311730-189vax2m	38	20	mice	mouse	NNS
cord-311730-189vax2m	38	21	[	[	-LRB-
cord-311730-189vax2m	38	22	9	9	CD
cord-311730-189vax2m	38	23	]	]	-RRB-
cord-311730-189vax2m	38	24	.	.	.
cord-311730-189vax2m	39	1	The	the	DT
cord-311730-189vax2m	39	2	potential	potential	JJ
cord-311730-189vax2m	39	3	mechanism(s	mechanism(s	NN
cord-311730-189vax2m	39	4	)	)	-RRB-
cord-311730-189vax2m	39	5	 	 	_SP
cord-311730-189vax2m	40	1	Cardiovascular	cardiovascular	JJ
cord-311730-189vax2m	40	2	effects	effect	NNS
cord-311730-189vax2m	40	3	,	,	,
cord-311730-189vax2m	40	4	including	include	VBG
cord-311730-189vax2m	40	5	vasodilation	vasodilation	NN
cord-311730-189vax2m	40	6	,	,	,
cord-311730-189vax2m	40	7	hypotension	hypotension	NN
cord-311730-189vax2m	40	8	,	,	,
cord-311730-189vax2m	40	9	decreased	decrease	VBD
cord-311730-189vax2m	40	10	myocardial	myocardial	JJ
cord-311730-189vax2m	40	11	performance	performance	NN
cord-311730-189vax2m	40	12	and	and	CC
cord-311730-189vax2m	40	13	arrhythmias	arrhythmia	NNS
cord-311730-189vax2m	40	14	have	have	VBP
cord-311730-189vax2m	40	15	been	be	VBN
cord-311730-189vax2m	40	16	reported	report	VBN
cord-311730-189vax2m	40	17	following	follow	VBG
cord-311730-189vax2m	40	18	chloroquine	chloroquine	NNP
cord-311730-189vax2m	40	19	administration	administration	NN
cord-311730-189vax2m	40	20	at	at	IN
cord-311730-189vax2m	40	21	high	high	JJ
cord-311730-189vax2m	40	22	doses	dose	NNS
cord-311730-189vax2m	40	23	(	(	-LRB-
cord-311730-189vax2m	40	24	reviewed	review	VBN
cord-311730-189vax2m	40	25	in	in	IN
cord-311730-189vax2m	40	26	Ben	Ben	NNP
cord-311730-189vax2m	40	27	-	-	HYPH
cord-311730-189vax2m	40	28	Zvi	Zvi	NNP
cord-311730-189vax2m	40	29	[	[	-LRB-
cord-311730-189vax2m	40	30	10	10	CD
cord-311730-189vax2m	40	31	]	]	-RRB-
cord-311730-189vax2m	40	32	)	)	-RRB-
cord-311730-189vax2m	40	33	.	.	.
cord-311730-189vax2m	41	1	The	the	DT
cord-311730-189vax2m	41	2	potential	potential	JJ
cord-311730-189vax2m	41	3	cardiotoxic	cardiotoxic	JJ
cord-311730-189vax2m	41	4	effects	effect	NNS
cord-311730-189vax2m	41	5	of	of	IN
cord-311730-189vax2m	41	6	chloroquine	chloroquine	NN
cord-311730-189vax2m	41	7	have	have	VBP
cord-311730-189vax2m	41	8	been	be	VBN
cord-311730-189vax2m	41	9	summarized	summarize	VBN
cord-311730-189vax2m	41	10	by	by	IN
cord-311730-189vax2m	41	11	several	several	JJ
cord-311730-189vax2m	41	12	groups	group	NNS
cord-311730-189vax2m	41	13	.	.	.
cord-311730-189vax2m	42	1	Blignaut	Blignaut	NNP
cord-311730-189vax2m	42	2	and	and	CC
cord-311730-189vax2m	42	3	colleagues	colleague	NNS
cord-311730-189vax2m	42	4	investigated	investigate	VBD
cord-311730-189vax2m	42	5	several	several	JJ
cord-311730-189vax2m	42	6	specific	specific	JJ
cord-311730-189vax2m	42	7	functional	functional	JJ
cord-311730-189vax2m	42	8	effects	effect	NNS
cord-311730-189vax2m	42	9	,	,	,
cord-311730-189vax2m	42	10	including	include	VBG
cord-311730-189vax2m	42	11	ex	ex	NN
cord-311730-189vax2m	42	12	vivo	vivo	FW
cord-311730-189vax2m	42	13	myocardial	myocardial	JJ
cord-311730-189vax2m	42	14	performance	performance	NN
cord-311730-189vax2m	42	15	and	and	CC
cord-311730-189vax2m	42	16	glucose	glucose	NN
cord-311730-189vax2m	42	17	uptake	uptake	NN
cord-311730-189vax2m	42	18	,	,	,
cord-311730-189vax2m	42	19	mitochondrial	mitochondrial	JJ
cord-311730-189vax2m	42	20	function	function	NN
cord-311730-189vax2m	42	21	and	and	CC
cord-311730-189vax2m	42	22	in	in	IN
cord-311730-189vax2m	42	23	vivo	vivo	NNP
cord-311730-189vax2m	42	24	heart	heart	NN
cord-311730-189vax2m	42	25	function	function	NN
cord-311730-189vax2m	42	26	[	[	-LRB-
cord-311730-189vax2m	42	27	11	11	CD
cord-311730-189vax2m	42	28	]	]	-RRB-
cord-311730-189vax2m	42	29	.	.	.
cord-311730-189vax2m	43	1	Control	control	NN
cord-311730-189vax2m	43	2	or	or	CC
cord-311730-189vax2m	43	3	obese	obese	JJ
cord-311730-189vax2m	43	4	male	male	JJ
cord-311730-189vax2m	43	5	Wister	Wister	NNP
cord-311730-189vax2m	43	6	rats	rat	NNS
cord-311730-189vax2m	43	7	were	be	VBD
cord-311730-189vax2m	43	8	used	use	VBN
cord-311730-189vax2m	43	9	in	in	IN
cord-311730-189vax2m	43	10	the	the	DT
cord-311730-189vax2m	43	11	experiments	experiment	NNS
cord-311730-189vax2m	43	12	and	and	CC
cord-311730-189vax2m	43	13	exposed	expose	VBN
cord-311730-189vax2m	43	14	to	to	IN
cord-311730-189vax2m	43	15	varying	vary	VBG
cord-311730-189vax2m	43	16	concentrations	concentration	NNS
cord-311730-189vax2m	43	17	of	of	IN
cord-311730-189vax2m	43	18	chloroquine	chloroquine	NN
cord-311730-189vax2m	43	19	.	.	.
cord-311730-189vax2m	44	1	Doses	dose	NNS
cord-311730-189vax2m	44	2	that	that	WDT
cord-311730-189vax2m	44	3	achieved	achieve	VBD
cord-311730-189vax2m	44	4	a	a	DT
cord-311730-189vax2m	44	5	concentration	concentration	NN
cord-311730-189vax2m	44	6	of	of	IN
cord-311730-189vax2m	44	7	10uM	10um	CD
cord-311730-189vax2m	44	8	or	or	CC
cord-311730-189vax2m	44	9	higher	high	JJR
cord-311730-189vax2m	44	10	decreased	decrease	VBD
cord-311730-189vax2m	44	11	heart	heart	NN
cord-311730-189vax2m	44	12	function	function	NN
cord-311730-189vax2m	44	13	.	.	.
cord-311730-189vax2m	45	1	Ex	Ex	NNP
cord-311730-189vax2m	45	2	vivo	vivo	NN
cord-311730-189vax2m	45	3	exposure	exposure	NN
cord-311730-189vax2m	45	4	did	do	VBD
cord-311730-189vax2m	45	5	not	not	RB
cord-311730-189vax2m	45	6	affect	affect	VB
cord-311730-189vax2m	45	7	mitochondrial	mitochondrial	JJ
cord-311730-189vax2m	45	8	function	function	NN
cord-311730-189vax2m	45	9	,	,	,
cord-311730-189vax2m	45	10	but	but	CC
cord-311730-189vax2m	45	11	chronic	chronic	JJ
cord-311730-189vax2m	45	12	exposure	exposure	NN
cord-311730-189vax2m	45	13	decreased	decrease	VBD
cord-311730-189vax2m	45	14	cardiac	cardiac	JJ
cord-311730-189vax2m	45	15	output	output	NN
cord-311730-189vax2m	45	16	.	.	.
cord-311730-189vax2m	46	1	The	the	DT
cord-311730-189vax2m	46	2	Centers	Centers	NNPS
cord-311730-189vax2m	46	3	for	for	IN
cord-311730-189vax2m	46	4	Disease	Disease	NNP
cord-311730-189vax2m	46	5	Control	Control	NNP
cord-311730-189vax2m	46	6	and	and	CC
cord-311730-189vax2m	46	7	Prevention	Prevention	NNP
cord-311730-189vax2m	46	8	(	(	-LRB-
cord-311730-189vax2m	46	9	CDC	CDC	NNP
cord-311730-189vax2m	46	10	)	)	-RRB-
cord-311730-189vax2m	46	11	posted	post	VBD
cord-311730-189vax2m	46	12	a	a	DT
cord-311730-189vax2m	46	13	warning	warning	NN
cord-311730-189vax2m	46	14	on	on	IN
cord-311730-189vax2m	46	15	their	-PRON-	PRP$
cord-311730-189vax2m	46	16	website	website	NN
cord-311730-189vax2m	46	17	about	about	IN
cord-311730-189vax2m	46	18	non	non	JJ
cord-311730-189vax2m	46	19	-	-	JJ
cord-311730-189vax2m	46	20	medicinal	medicinal	JJ
cord-311730-189vax2m	46	21	chloroquine	chloroquine	NN
cord-311730-189vax2m	46	22	phosphate	phosphate	NN
cord-311730-189vax2m	46	23	products	product	NNS
cord-311730-189vax2m	46	24	and	and	CC
cord-311730-189vax2m	46	25	their	-PRON-	PRP$
cord-311730-189vax2m	46	26	potential	potential	JJ
cord-311730-189vax2m	46	27	risks	risk	NNS
cord-311730-189vax2m	46	28	to	to	IN
cord-311730-189vax2m	46	29	humans	human	NNS
cord-311730-189vax2m	46	30	after	after	IN
cord-311730-189vax2m	46	31	ingestion	ingestion	NN
cord-311730-189vax2m	46	32	,	,	,
cord-311730-189vax2m	46	33	including	include	VBG
cord-311730-189vax2m	46	34	death	death	NN
cord-311730-189vax2m	46	35	(	(	-LRB-
cord-311730-189vax2m	46	36	www.cdc.com	www.cdc.com	ADD
cord-311730-189vax2m	46	37	)	)	-RRB-
cord-311730-189vax2m	46	38	.	.	.
cord-311730-189vax2m	47	1	It	-PRON-	PRP
cord-311730-189vax2m	47	2	is	be	VBZ
cord-311730-189vax2m	47	3	also	also	RB
cord-311730-189vax2m	47	4	important	important	JJ
cord-311730-189vax2m	47	5	to	to	TO
cord-311730-189vax2m	47	6	be	be	VB
cord-311730-189vax2m	47	7	mindful	mindful	JJ
cord-311730-189vax2m	47	8	of	of	IN
cord-311730-189vax2m	47	9	and	and	CC
cord-311730-189vax2m	47	10	attentive	attentive	JJ
cord-311730-189vax2m	47	11	to	to	IN
cord-311730-189vax2m	47	12	the	the	DT
cord-311730-189vax2m	47	13	potential	potential	JJ
cord-311730-189vax2m	47	14	risk	risk	NN
cord-311730-189vax2m	47	15	of	of	IN
cord-311730-189vax2m	47	16	medicinal	medicinal	JJ
cord-311730-189vax2m	47	17	chloroquine	chloroquine	NNP
cord-311730-189vax2m	47	18	and	and	CC
cord-311730-189vax2m	47	19	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	47	20	(	(	-LRB-
cord-311730-189vax2m	47	21	to	to	TO
cord-311730-189vax2m	47	22	be	be	VB
cord-311730-189vax2m	47	23	discussed	discuss	VBN
cord-311730-189vax2m	47	24	)	)	-RRB-
cord-311730-189vax2m	47	25	when	when	WRB
cord-311730-189vax2m	47	26	taken	take	VBN
cord-311730-189vax2m	47	27	in	in	RP
cord-311730-189vax2m	47	28	doses	dose	NNS
cord-311730-189vax2m	47	29	higher	higher	RBR
cord-311730-189vax2m	47	30	that	that	DT
cord-311730-189vax2m	47	31	recommended	recommend	VBD
cord-311730-189vax2m	47	32	.	.	.
cord-311730-189vax2m	48	1	Cardiac	cardiac	JJ
cord-311730-189vax2m	48	2	arrhythmias	arrhythmia	NNS
cord-311730-189vax2m	48	3	,	,	,
cord-311730-189vax2m	48	4	including	include	VBG
cord-311730-189vax2m	48	5	torsades	torsades	NNP
cord-311730-189vax2m	48	6	de	de	NNP
cord-311730-189vax2m	48	7	pointe	pointe	NNP
cord-311730-189vax2m	48	8	ventricular	ventricular	JJ
cord-311730-189vax2m	48	9	tachycardia	tachycardia	NN
cord-311730-189vax2m	48	10	stemming	stem	VBG
cord-311730-189vax2m	48	11	from	from	IN
cord-311730-189vax2m	48	12	Q	Q	NNP
cord-311730-189vax2m	48	13	-	-	HYPH
cord-311730-189vax2m	48	14	Tc	Tc	NNP
cord-311730-189vax2m	48	15	prolongation	prolongation	NN
cord-311730-189vax2m	48	16	and	and	CC
cord-311730-189vax2m	48	17	often	often	RB
cord-311730-189vax2m	48	18	,	,	,
cord-311730-189vax2m	48	19	but	but	CC
cord-311730-189vax2m	48	20	not	not	RB
cord-311730-189vax2m	48	21	always	always	RB
cord-311730-189vax2m	48	22	concomitant	concomitant	JJ
cord-311730-189vax2m	48	23	hypokalemia	hypokalemia	NN
cord-311730-189vax2m	48	24	can	can	MD
cord-311730-189vax2m	48	25	occur	occur	VB
cord-311730-189vax2m	48	26	(	(	-LRB-
cord-311730-189vax2m	48	27	Figs	fig	NNS
cord-311730-189vax2m	48	28	.	.	.
cord-311730-189vax2m	48	29	4	4	CD
cord-311730-189vax2m	48	30	and	and	CC
cord-311730-189vax2m	48	31	5	5	CD
cord-311730-189vax2m	48	32	)	)	-RRB-
cord-311730-189vax2m	48	33	.	.	.
cord-311730-189vax2m	49	1	Additional	additional	JJ
cord-311730-189vax2m	49	2	electrocardiographic	electrocardiographic	JJ
cord-311730-189vax2m	49	3	effects	effect	NNS
cord-311730-189vax2m	49	4	include	include	VBP
cord-311730-189vax2m	49	5	bundle	bundle	NN
cord-311730-189vax2m	49	6	branch	branch	NN
cord-311730-189vax2m	49	7	block	block	NN
cord-311730-189vax2m	49	8	and	and	CC
cord-311730-189vax2m	49	9	atrioventricular	atrioventricular	JJ
cord-311730-189vax2m	49	10	(	(	-LRB-
cord-311730-189vax2m	49	11	AV	av	NN
cord-311730-189vax2m	49	12	)	)	-RRB-
cord-311730-189vax2m	49	13	block	block	NN
cord-311730-189vax2m	49	14	.	.	.
cord-311730-189vax2m	50	1	Non	non	JJ
cord-311730-189vax2m	50	2	-	-	JJ
cord-311730-189vax2m	50	3	cardiovascular	cardiovascular	JJ
cord-311730-189vax2m	50	4	adverse	adverse	JJ
cord-311730-189vax2m	50	5	effects	effect	NNS
cord-311730-189vax2m	50	6	that	that	WDT
cord-311730-189vax2m	50	7	have	have	VBP
cord-311730-189vax2m	50	8	been	be	VBN
cord-311730-189vax2m	50	9	reported	report	VBN
cord-311730-189vax2m	50	10	range	range	NN
cord-311730-189vax2m	50	11	from	from	IN
cord-311730-189vax2m	50	12	nausea	nausea	NN
cord-311730-189vax2m	50	13	,	,	,
cord-311730-189vax2m	50	14	vomiting	vomiting	NN
cord-311730-189vax2m	50	15	and	and	CC
cord-311730-189vax2m	50	16	diarrhea	diarrhea	NN
cord-311730-189vax2m	50	17	to	to	IN
cord-311730-189vax2m	50	18	thrombocytopenia	thrombocytopenia	NN
cord-311730-189vax2m	50	19	,	,	,
cord-311730-189vax2m	50	20	aplastic	aplastic	JJ
cord-311730-189vax2m	50	21	anemia	anemia	NN
cord-311730-189vax2m	50	22	,	,	,
cord-311730-189vax2m	50	23	shock	shock	NN
cord-311730-189vax2m	50	24	,	,	,
cord-311730-189vax2m	50	25	seizures	seizure	NNS
cord-311730-189vax2m	50	26	,	,	,
cord-311730-189vax2m	50	27	coma	coma	NN
cord-311730-189vax2m	50	28	and	and	CC
cord-311730-189vax2m	50	29	death	death	NN
cord-311730-189vax2m	50	30	.	.	.
cord-311730-189vax2m	51	1	There	there	EX
cord-311730-189vax2m	51	2	are	be	VBP
cord-311730-189vax2m	51	3	in	in	IN
cord-311730-189vax2m	51	4	vitro	vitro	FW
cord-311730-189vax2m	51	5	data	datum	NNS
cord-311730-189vax2m	51	6	for	for	IN
cord-311730-189vax2m	51	7	chloroquine	chloroquine	NN
cord-311730-189vax2m	51	8	and	and	CC
cord-311730-189vax2m	51	9	SARS	SARS	NNP
cord-311730-189vax2m	51	10	-	-	HYPH
cord-311730-189vax2m	51	11	CoV	cov	NN
cord-311730-189vax2m	51	12	replication	replication	NN
cord-311730-189vax2m	51	13	[	[	-LRB-
cord-311730-189vax2m	51	14	12	12	CD
cord-311730-189vax2m	51	15	]	]	-RRB-
cord-311730-189vax2m	51	16	.	.	.
cord-311730-189vax2m	52	1	Kayaerts	Kayaerts	NNP
cord-311730-189vax2m	52	2	et	et	NNP
cord-311730-189vax2m	52	3	al	al	NNP
cord-311730-189vax2m	52	4	.	.	.
cord-311730-189vax2m	53	1	tested	test	VBD
cord-311730-189vax2m	53	2	its	-PRON-	PRP$
cord-311730-189vax2m	53	3	antiviral	antiviral	JJ
cord-311730-189vax2m	53	4	potential	potential	NN
cord-311730-189vax2m	53	5	against	against	IN
cord-311730-189vax2m	53	6	SARS	SARS	NNP
cord-311730-189vax2m	53	7	-	-	HYPH
cord-311730-189vax2m	53	8	CoV	CoV	NNP
cord-311730-189vax2m	53	9	-	-	HYPH
cord-311730-189vax2m	53	10	induced	induce	VBN
cord-311730-189vax2m	53	11	cytopathicity	cytopathicity	NN
cord-311730-189vax2m	53	12	in	in	IN
cord-311730-189vax2m	53	13	Vero	Vero	NNP
cord-311730-189vax2m	53	14	E6	E6	NNP
cord-311730-189vax2m	53	15	cell	cell	NN
cord-311730-189vax2m	53	16	culture	culture	NN
cord-311730-189vax2m	53	17	.	.	.
cord-311730-189vax2m	54	1	The	the	DT
cord-311730-189vax2m	54	2	IC50	IC50	NNP
cord-311730-189vax2m	54	3	of	of	IN
cord-311730-189vax2m	54	4	chloroquine	chloroquine	NN
cord-311730-189vax2m	54	5	for	for	IN
cord-311730-189vax2m	54	6	antiviral	antiviral	JJ
cord-311730-189vax2m	54	7	activity	activity	NN
cord-311730-189vax2m	54	8	(	(	-LRB-
cord-311730-189vax2m	54	9	8.8	8.8	CD
cord-311730-189vax2m	54	10	±	±	CD
cord-311730-189vax2m	54	11	1.2	1.2	CD
cord-311730-189vax2m	54	12	μM	μM	NNP
cord-311730-189vax2m	54	13	)	)	-RRB-
cord-311730-189vax2m	54	14	was	be	VBD
cord-311730-189vax2m	54	15	significantly	significantly	RB
cord-311730-189vax2m	54	16	lower	low	JJR
cord-311730-189vax2m	54	17	than	than	IN
cord-311730-189vax2m	54	18	its	-PRON-	PRP$
cord-311730-189vax2m	54	19	cytostatic	cytostatic	JJ
cord-311730-189vax2m	54	20	activity	activity	NN
cord-311730-189vax2m	54	21	;	;	:
cord-311730-189vax2m	54	22	CC50	CC50	NNP
cord-311730-189vax2m	54	23	(	(	-LRB-
cord-311730-189vax2m	54	24	261.3	261.3	CD
cord-311730-189vax2m	54	25	±	±	CD
cord-311730-189vax2m	54	26	14.5	14.5	CD
cord-311730-189vax2m	54	27	μM	μM	NNP
cord-311730-189vax2m	54	28	)	)	-RRB-
cord-311730-189vax2m	54	29	and	and	CC
cord-311730-189vax2m	54	30	approximated	approximate	VBD
cord-311730-189vax2m	54	31	the	the	DT
cord-311730-189vax2m	54	32	plasma	plasma	NN
cord-311730-189vax2m	54	33	concentrations	concentration	NNS
cord-311730-189vax2m	54	34	commonly	commonly	RB
cord-311730-189vax2m	54	35	achieved	achieve	VBN
cord-311730-189vax2m	54	36	during	during	IN
cord-311730-189vax2m	54	37	treatment	treatment	NN
cord-311730-189vax2m	54	38	of	of	IN
cord-311730-189vax2m	54	39	malaria	malaria	NN
cord-311730-189vax2m	54	40	.	.	.
cord-311730-189vax2m	55	1	The	the	DT
cord-311730-189vax2m	55	2	same	same	JJ
cord-311730-189vax2m	55	3	group	group	NN
cord-311730-189vax2m	55	4	[	[	-LRB-
cord-311730-189vax2m	55	5	13	13	CD
cord-311730-189vax2m	55	6	]	]	-RRB-
cord-311730-189vax2m	55	7	investigated	investigate	VBN
cord-311730-189vax2m	55	8	whether	whether	IN
cord-311730-189vax2m	55	9	chloroquine	chloroquine	NN
cord-311730-189vax2m	55	10	,	,	,
cord-311730-189vax2m	55	11	provided	provide	VBN
cord-311730-189vax2m	55	12	either	either	CC
cord-311730-189vax2m	55	13	transplacentally	transplacentally	RB
cord-311730-189vax2m	55	14	or	or	CC
cord-311730-189vax2m	55	15	via	via	IN
cord-311730-189vax2m	55	16	maternal	maternal	JJ
cord-311730-189vax2m	55	17	milk	milk	NN
cord-311730-189vax2m	55	18	could	could	MD
cord-311730-189vax2m	55	19	prevent	prevent	VB
cord-311730-189vax2m	55	20	Electrocardiographic	Electrocardiographic	NNP
cord-311730-189vax2m	55	21	QTc	qtc	VB
cord-311730-189vax2m	55	22	interval	interval	NN
cord-311730-189vax2m	55	23	prolongation	prolongation	NN
cord-311730-189vax2m	55	24	.	.	.
cord-311730-189vax2m	56	1	The	the	DT
cord-311730-189vax2m	56	2	QT	QT	NNP
cord-311730-189vax2m	56	3	interval	interval	NN
cord-311730-189vax2m	56	4	represents	represent	VBZ
cord-311730-189vax2m	56	5	the	the	DT
cord-311730-189vax2m	56	6	period	period	NN
cord-311730-189vax2m	56	7	of	of	IN
cord-311730-189vax2m	56	8	ventricular	ventricular	JJ
cord-311730-189vax2m	56	9	depolarization	depolarization	NN
cord-311730-189vax2m	56	10	(	(	-LRB-
cord-311730-189vax2m	56	11	QRS	qrs	NN
cord-311730-189vax2m	56	12	interval	interval	NN
cord-311730-189vax2m	56	13	)	)	-RRB-
cord-311730-189vax2m	56	14	and	and	CC
cord-311730-189vax2m	56	15	repolarization	repolarization	NN
cord-311730-189vax2m	56	16	(	(	-LRB-
cord-311730-189vax2m	56	17	ST	ST	NNP
cord-311730-189vax2m	56	18	interval	interval	NN
cord-311730-189vax2m	56	19	)	)	-RRB-
cord-311730-189vax2m	56	20	.	.	.
cord-311730-189vax2m	57	1	It	-PRON-	PRP
cord-311730-189vax2m	57	2	is	be	VBZ
cord-311730-189vax2m	57	3	corrected	correct	VBN
cord-311730-189vax2m	57	4	for	for	IN
cord-311730-189vax2m	57	5	the	the	DT
cord-311730-189vax2m	57	6	heart	heart	NN
cord-311730-189vax2m	57	7	rate	rate	NN
cord-311730-189vax2m	57	8	and	and	CC
cord-311730-189vax2m	57	9	referred	refer	VBD
cord-311730-189vax2m	57	10	to	to	IN
cord-311730-189vax2m	57	11	as	as	IN
cord-311730-189vax2m	57	12	the	the	DT
cord-311730-189vax2m	57	13	QTc	QTc	NNP
cord-311730-189vax2m	57	14	interval	interval	NN
cord-311730-189vax2m	57	15	.	.	.
cord-311730-189vax2m	58	1	Prolongation	prolongation	NN
cord-311730-189vax2m	58	2	of	of	IN
cord-311730-189vax2m	58	3	repolarization	repolarization	NN
cord-311730-189vax2m	58	4	is	be	VBZ
cord-311730-189vax2m	58	5	caused	cause	VBN
cord-311730-189vax2m	58	6	by	by	IN
cord-311730-189vax2m	58	7	an	an	DT
cord-311730-189vax2m	58	8	increase	increase	NN
cord-311730-189vax2m	58	9	of	of	IN
cord-311730-189vax2m	58	10	inward	inward	JJ
cord-311730-189vax2m	58	11	current	current	JJ
cord-311730-189vax2m	58	12	through	through	IN
cord-311730-189vax2m	58	13	sodium	sodium	NN
cord-311730-189vax2m	58	14	or	or	CC
cord-311730-189vax2m	58	15	calcium	calcium	NN
cord-311730-189vax2m	58	16	channels	channel	NNS
cord-311730-189vax2m	58	17	or	or	CC
cord-311730-189vax2m	58	18	a	a	DT
cord-311730-189vax2m	58	19	decrease	decrease	NN
cord-311730-189vax2m	58	20	in	in	IN
cord-311730-189vax2m	58	21	outward	outward	JJ
cord-311730-189vax2m	58	22	current	current	JJ
cord-311730-189vax2m	58	23	through	through	IN
cord-311730-189vax2m	58	24	potassium	potassium	NN
cord-311730-189vax2m	58	25	channels	channel	NNS
cord-311730-189vax2m	58	26	.	.	.
cord-311730-189vax2m	59	1	The	the	DT
cord-311730-189vax2m	59	2	normal	normal	JJ
cord-311730-189vax2m	59	3	value	value	NN
cord-311730-189vax2m	59	4	in	in	IN
cord-311730-189vax2m	59	5	adults	adult	NNS
cord-311730-189vax2m	59	6	is	be	VBZ
cord-311730-189vax2m	59	7	470	470	CD
cord-311730-189vax2m	59	8	ms	m	NNS
cord-311730-189vax2m	59	9	in	in	IN
cord-311730-189vax2m	59	10	men	man	NNS
cord-311730-189vax2m	59	11	and	and	CC
cord-311730-189vax2m	59	12	480	480	CD
cord-311730-189vax2m	59	13	ms	m	NNS
cord-311730-189vax2m	59	14	in	in	IN
cord-311730-189vax2m	59	15	women	woman	NNS
cord-311730-189vax2m	59	16	.	.	.
cord-311730-189vax2m	60	1	The	the	DT
cord-311730-189vax2m	60	2	normal	normal	JJ
cord-311730-189vax2m	60	3	QTc	qtc	NN
cord-311730-189vax2m	60	4	interval	interval	NN
cord-311730-189vax2m	60	5	is	be	VBZ
cord-311730-189vax2m	60	6	shorter	short	JJR
cord-311730-189vax2m	60	7	in	in	IN
cord-311730-189vax2m	60	8	children	child	NNS
cord-311730-189vax2m	60	9	.	.	.
cord-311730-189vax2m	61	1	A	a	DT
cord-311730-189vax2m	61	2	sudden	sudden	JJ
cord-311730-189vax2m	61	3	prolongation	prolongation	NN
cord-311730-189vax2m	61	4	of	of	IN
cord-311730-189vax2m	61	5	QTc	QTc	NNP
cord-311730-189vax2m	61	6	interval	interval	NN
cord-311730-189vax2m	61	7	(	(	-LRB-
cord-311730-189vax2m	61	8	greater	great	JJR
cord-311730-189vax2m	61	9	than	than	IN
cord-311730-189vax2m	61	10	20	20	CD
cord-311730-189vax2m	61	11	-	-	SYM
cord-311730-189vax2m	61	12	30	30	CD
cord-311730-189vax2m	61	13	%	%	NN
cord-311730-189vax2m	61	14	above	above	IN
cord-311730-189vax2m	61	15	baseline	baseline	NN
cord-311730-189vax2m	61	16	)	)	-RRB-
cord-311730-189vax2m	61	17	or	or	CC
cord-311730-189vax2m	61	18	an	an	DT
cord-311730-189vax2m	61	19	absolute	absolute	JJ
cord-311730-189vax2m	61	20	value	value	NN
cord-311730-189vax2m	61	21	>	>	XX
cord-311730-189vax2m	62	1	500	500	CD
cord-311730-189vax2m	62	2	ms	ms	NNP
cord-311730-189vax2m	62	3	increases	increase	VBZ
cord-311730-189vax2m	62	4	the	the	DT
cord-311730-189vax2m	62	5	risk	risk	NN
cord-311730-189vax2m	62	6	for	for	IN
cord-311730-189vax2m	62	7	ventricular	ventricular	JJ
cord-311730-189vax2m	62	8	tachycardia	tachycardia	NN
cord-311730-189vax2m	62	9	that	that	WDT
cord-311730-189vax2m	62	10	can	can	MD
cord-311730-189vax2m	62	11	be	be	VB
cord-311730-189vax2m	62	12	life	life	NN
cord-311730-189vax2m	62	13	-	-	HYPH
cord-311730-189vax2m	62	14	threatening	threaten	VBG
cord-311730-189vax2m	62	15	.	.	.
cord-311730-189vax2m	63	1	Other	other	JJ
cord-311730-189vax2m	63	2	intervals	interval	NNS
cord-311730-189vax2m	63	3	,	,	,
cord-311730-189vax2m	63	4	including	include	VBG
cord-311730-189vax2m	63	5	the	the	DT
cord-311730-189vax2m	63	6	PR	pr	NN
cord-311730-189vax2m	63	7	(	(	-LRB-
cord-311730-189vax2m	63	8	atrial	atrial	JJ
cord-311730-189vax2m	63	9	depolarization	depolarization	NN
cord-311730-189vax2m	63	10	and	and	CC
cord-311730-189vax2m	63	11	conduction	conduction	NN
cord-311730-189vax2m	63	12	leading	lead	VBG
cord-311730-189vax2m	63	13	up	up	IN
cord-311730-189vax2m	63	14	to	to	IN
cord-311730-189vax2m	63	15	ventricular	ventricular	JJ
cord-311730-189vax2m	63	16	depolarization	depolarization	NN
cord-311730-189vax2m	63	17	)	)	-RRB-
cord-311730-189vax2m	63	18	are	be	VBP
cord-311730-189vax2m	63	19	shown	show	VBN
cord-311730-189vax2m	63	20	HCoV	HCoV	NNP
cord-311730-189vax2m	63	21	-	-	HYPH
cord-311730-189vax2m	63	22	OC43-induced	oc43-induce	VBN
cord-311730-189vax2m	63	23	death	death	NN
cord-311730-189vax2m	63	24	in	in	IN
cord-311730-189vax2m	63	25	newborn	newborn	JJ
cord-311730-189vax2m	63	26	mice	mouse	NNS
cord-311730-189vax2m	63	27	.	.	.
cord-311730-189vax2m	64	1	The	the	DT
cord-311730-189vax2m	64	2	highest	high	JJS
cord-311730-189vax2m	64	3	survival	survival	NN
cord-311730-189vax2m	64	4	rate	rate	NN
cord-311730-189vax2m	64	5	(	(	-LRB-
cord-311730-189vax2m	64	6	98.6	98.6	CD
cord-311730-189vax2m	64	7	%	%	NN
cord-311730-189vax2m	64	8	)	)	-RRB-
cord-311730-189vax2m	64	9	occurred	occur	VBD
cord-311730-189vax2m	64	10	when	when	WRB
cord-311730-189vax2m	64	11	mother	mother	NN
cord-311730-189vax2m	64	12	mice	mouse	NNS
cord-311730-189vax2m	64	13	received	receive	VBD
cord-311730-189vax2m	64	14	15	15	CD
cord-311730-189vax2m	64	15	mg	mg	NN
cord-311730-189vax2m	64	16	of	of	IN
cord-311730-189vax2m	64	17	chloroquine	chloroquine	NN
cord-311730-189vax2m	64	18	per	per	IN
cord-311730-189vax2m	64	19	kg	kg	NNS
cord-311730-189vax2m	64	20	of	of	IN
cord-311730-189vax2m	64	21	body	body	NN
cord-311730-189vax2m	64	22	weight	weight	NN
cord-311730-189vax2m	64	23	daily	daily	RB
cord-311730-189vax2m	64	24	.	.	.
cord-311730-189vax2m	65	1	Wang	Wang	NNP
cord-311730-189vax2m	65	2	and	and	CC
cord-311730-189vax2m	65	3	colleagues	colleague	NNS
cord-311730-189vax2m	65	4	[	[	-LRB-
cord-311730-189vax2m	65	5	14	14	CD
cord-311730-189vax2m	65	6	]	]	-RRB-
cord-311730-189vax2m	65	7	tested	test	VBD
cord-311730-189vax2m	65	8	the	the	DT
cord-311730-189vax2m	65	9	in	in	FW
cord-311730-189vax2m	65	10	vitro	vitro	FW
cord-311730-189vax2m	65	11	antiviral	antiviral	JJ
cord-311730-189vax2m	65	12	activity	activity	NN
cord-311730-189vax2m	65	13	of	of	IN
cord-311730-189vax2m	65	14	chloroquine	chloroquine	NN
cord-311730-189vax2m	65	15	in	in	IN
cord-311730-189vax2m	65	16	Vero	Vero	NNP
cord-311730-189vax2m	65	17	E6	E6	NNP
cord-311730-189vax2m	65	18	cells	cell	NNS
cord-311730-189vax2m	65	19	infected	infect	VBN
cord-311730-189vax2m	65	20	with	with	IN
cord-311730-189vax2m	65	21	nCoV-2019BetaCoV	ncov-2019betacov	NN
cord-311730-189vax2m	66	1	/Wuhan	/Wuhan	,
cord-311730-189vax2m	66	2	/	/	SYM
cord-311730-189vax2m	66	3	WIV04/2019	WIV04/2019	NNP
cord-311730-189vax2m	66	4	at	at	IN
cord-311730-189vax2m	66	5	a	a	DT
cord-311730-189vax2m	66	6	multiplicity	multiplicity	NN
cord-311730-189vax2m	66	7	of	of	IN
cord-311730-189vax2m	66	8	infection	infection	NN
cord-311730-189vax2m	66	9	(	(	-LRB-
cord-311730-189vax2m	66	10	MOI	MOI	NNP
cord-311730-189vax2m	66	11	)	)	-RRB-
cord-311730-189vax2m	66	12	of	of	IN
cord-311730-189vax2m	66	13	0.05	0.05	CD
cord-311730-189vax2m	66	14	.	.	.
cord-311730-189vax2m	67	1	Chloroquine	Chloroquine	NNP
cord-311730-189vax2m	67	2	(	(	-LRB-
cord-311730-189vax2m	67	3	EC	EC	NNP
cord-311730-189vax2m	67	4	50	50	CD
cord-311730-189vax2m	67	5	=	=	SYM
cord-311730-189vax2m	67	6	1.13	1.13	CD
cord-311730-189vax2m	68	1	μM	μM	NNP
cord-311730-189vax2m	69	1	;	;	:
cord-311730-189vax2m	69	2	CC	CC	NNP
cord-311730-189vax2m	69	3	50	50	CD
cord-311730-189vax2m	69	4	>	>	XX
cord-311730-189vax2m	70	1	100	100	CD
cord-311730-189vax2m	70	2	μM	μm	NN
cord-311730-189vax2m	70	3	,	,	,
cord-311730-189vax2m	70	4	SI	SI	NNP
cord-311730-189vax2m	70	5	>	>	XX
cord-311730-189vax2m	70	6	88.50	88.50	CD
cord-311730-189vax2m	70	7	)	)	-RRB-
cord-311730-189vax2m	71	1	blocked	block	VBN
cord-311730-189vax2m	71	2	virus	virus	NN
cord-311730-189vax2m	71	3	infection	infection	NN
cord-311730-189vax2m	71	4	at	at	IN
cord-311730-189vax2m	71	5	lowmicromolar	lowmicromolar	NNP
cord-311730-189vax2m	71	6	concentrations	concentration	NNS
cord-311730-189vax2m	71	7	at	at	IN
cord-311730-189vax2m	71	8	both	both	DT
cord-311730-189vax2m	71	9	entry	entry	NN
cord-311730-189vax2m	71	10	,	,	,
cord-311730-189vax2m	71	11	and	and	CC
cord-311730-189vax2m	71	12	at	at	IN
cord-311730-189vax2m	71	13	post	post	JJ
cord-311730-189vax2m	71	14	-	-	JJ
cord-311730-189vax2m	71	15	entry	entry	JJ
cord-311730-189vax2m	71	16	stages	stage	NNS
cord-311730-189vax2m	71	17	.	.	.
cord-311730-189vax2m	72	1	Huang	Huang	NNP
cord-311730-189vax2m	72	2	and	and	CC
cord-311730-189vax2m	72	3	colleagues	colleague	NNS
cord-311730-189vax2m	72	4	[	[	-LRB-
cord-311730-189vax2m	72	5	15	15	CD
cord-311730-189vax2m	72	6	]	]	-RRB-
cord-311730-189vax2m	72	7	conducted	conduct	VBD
cord-311730-189vax2m	72	8	a	a	DT
cord-311730-189vax2m	72	9	small	small	JJ
cord-311730-189vax2m	72	10	pilot	pilot	NN
cord-311730-189vax2m	72	11	study	study	NN
cord-311730-189vax2m	72	12	in	in	IN
cord-311730-189vax2m	72	13	patients	patient	NNS
cord-311730-189vax2m	72	14	with	with	IN
cord-311730-189vax2m	72	15	Covid-19	covid-19	NN
cord-311730-189vax2m	72	16	.	.	.
cord-311730-189vax2m	73	1	A	a	DT
cord-311730-189vax2m	73	2	total	total	NN
cord-311730-189vax2m	73	3	of	of	IN
cord-311730-189vax2m	73	4	22	22	CD
cord-311730-189vax2m	73	5	patients	patient	NNS
cord-311730-189vax2m	73	6	were	be	VBD
cord-311730-189vax2m	73	7	divided	divide	VBN
cord-311730-189vax2m	73	8	into	into	IN
cord-311730-189vax2m	73	9	two	two	CD
cord-311730-189vax2m	73	10	groups	group	NNS
cord-311730-189vax2m	73	11	:	:	:
cord-311730-189vax2m	73	12	one	one	CD
cord-311730-189vax2m	73	13	(	(	-LRB-
cord-311730-189vax2m	73	14	n	n	NN
cord-311730-189vax2m	73	15	=	=	SYM
cord-311730-189vax2m	73	16	10	10	CD
cord-311730-189vax2m	73	17	)	)	-RRB-
cord-311730-189vax2m	73	18	treated	treat	VBN
cord-311730-189vax2m	73	19	with	with	IN
cord-311730-189vax2m	73	20	chloroquine	chloroquine	NN
cord-311730-189vax2m	73	21	(	(	-LRB-
cord-311730-189vax2m	73	22	500	500	CD
cord-311730-189vax2m	73	23	mg	mg	NNP
cord-311730-189vax2m	73	24	,	,	,
cord-311730-189vax2m	73	25	oral	oral	JJ
cord-311730-189vax2m	73	26	administration	administration	NN
cord-311730-189vax2m	73	27	,	,	,
cord-311730-189vax2m	73	28	twice	twice	RB
cord-311730-189vax2m	73	29	daily	daily	JJ
cord-311730-189vax2m	73	30	)	)	-RRB-
cord-311730-189vax2m	73	31	and	and	CC
cord-311730-189vax2m	73	32	another	another	DT
cord-311730-189vax2m	73	33	(	(	-LRB-
cord-311730-189vax2m	73	34	n	n	NN
cord-311730-189vax2m	73	35	=	=	SYM
cord-311730-189vax2m	73	36	12	12	CD
cord-311730-189vax2m	73	37	)	)	-RRB-
cord-311730-189vax2m	73	38	with	with	IN
cord-311730-189vax2m	73	39	lopinavir	lopinavir	NNS
cord-311730-189vax2m	73	40	/	/	SYM
cord-311730-189vax2m	73	41	ritonavir	ritonavir	NNP
cord-311730-189vax2m	73	42	(	(	-LRB-
cord-311730-189vax2m	73	43	400/100	400/100	CD
cord-311730-189vax2m	73	44	mg	mg	NNP
cord-311730-189vax2m	73	45	,	,	,
cord-311730-189vax2m	73	46	oral	oral	JJ
cord-311730-189vax2m	73	47	administration	administration	NN
cord-311730-189vax2m	73	48	,	,	,
cord-311730-189vax2m	73	49	twice	twice	RB
cord-311730-189vax2m	73	50	daily	daily	RB
cord-311730-189vax2m	73	51	)	)	-RRB-
cord-311730-189vax2m	73	52	for	for	IN
cord-311730-189vax2m	73	53	10	10	CD
cord-311730-189vax2m	73	54	days	day	NNS
cord-311730-189vax2m	73	55	and	and	CC
cord-311730-189vax2m	73	56	monitored	monitor	VBD
cord-311730-189vax2m	73	57	for	for	IN
cord-311730-189vax2m	73	58	a	a	DT
cord-311730-189vax2m	73	59	total	total	NN
cord-311730-189vax2m	73	60	of	of	IN
cord-311730-189vax2m	73	61	14	14	CD
cord-311730-189vax2m	73	62	days	day	NNS
cord-311730-189vax2m	73	63	.	.	.
cord-311730-189vax2m	74	1	Chloroquine	chloroquine	NN
cord-311730-189vax2m	74	2	treated	treat	VBD
cord-311730-189vax2m	74	3	patients	patient	NNS
cord-311730-189vax2m	74	4	were	be	VBD
cord-311730-189vax2m	74	5	more	more	RBR
cord-311730-189vax2m	74	6	likely	likely	JJ
cord-311730-189vax2m	74	7	to	to	TO
cord-311730-189vax2m	74	8	turn	turn	VB
cord-311730-189vax2m	74	9	negative	negative	JJ
cord-311730-189vax2m	74	10	for	for	IN
cord-311730-189vax2m	74	11	viral	viral	JJ
cord-311730-189vax2m	74	12	RNA	RNA	NNP
cord-311730-189vax2m	74	13	.	.	.
cord-311730-189vax2m	75	1	In	in	IN
cord-311730-189vax2m	75	2	fact	fact	NN
cord-311730-189vax2m	75	3	,	,	,
cord-311730-189vax2m	75	4	by	by	IN
cord-311730-189vax2m	75	5	day	day	NN
cord-311730-189vax2m	75	6	13	13	CD
cord-311730-189vax2m	75	7	,	,	,
cord-311730-189vax2m	75	8	all	all	PDT
cord-311730-189vax2m	75	9	the	the	DT
cord-311730-189vax2m	75	10	chloroquine	chloroquine	NN
cord-311730-189vax2m	75	11	-	-	HYPH
cord-311730-189vax2m	75	12	treated	treat	VBN
cord-311730-189vax2m	75	13	patients	patient	NNS
cord-311730-189vax2m	75	14	became	become	VBD
cord-311730-189vax2m	75	15	negative	negative	JJ
cord-311730-189vax2m	75	16	for	for	IN
cord-311730-189vax2m	75	17	viral	viral	JJ
cord-311730-189vax2m	75	18	RNA	RNA	NNP
cord-311730-189vax2m	75	19	test	test	NN
cord-311730-189vax2m	75	20	.	.	.
cord-311730-189vax2m	76	1	In	in	IN
cord-311730-189vax2m	76	2	the	the	DT
cord-311730-189vax2m	76	3	lopinavir	lopinavir	NNS
cord-311730-189vax2m	76	4	/	/	SYM
cord-311730-189vax2m	76	5	ritonavir	ritonavir	NNP
cord-311730-189vax2m	76	6	treated	treat	VBN
cord-311730-189vax2m	76	7	patients	patient	NNS
cord-311730-189vax2m	76	8	,	,	,
cord-311730-189vax2m	76	9	11	11	CD
cord-311730-189vax2m	76	10	out	out	IN
cord-311730-189vax2m	76	11	of	of	IN
cord-311730-189vax2m	76	12	12	12	CD
cord-311730-189vax2m	76	13	turned	turn	VBN
cord-311730-189vax2m	76	14	negative	negative	JJ
cord-311730-189vax2m	76	15	by	by	IN
cord-311730-189vax2m	76	16	Day	Day	NNP
cord-311730-189vax2m	76	17	14	14	CD
cord-311730-189vax2m	76	18	.	.	.
cord-311730-189vax2m	77	1	Improvement	improvement	NN
cord-311730-189vax2m	77	2	in	in	IN
cord-311730-189vax2m	77	3	pulmonary	pulmonary	JJ
cord-311730-189vax2m	77	4	CT	CT	NNP
cord-311730-189vax2m	77	5	scans	scan	NNS
cord-311730-189vax2m	77	6	occurred	occur	VBD
cord-311730-189vax2m	77	7	at	at	IN
cord-311730-189vax2m	77	8	twice	twice	RB
cord-311730-189vax2m	77	9	the	the	DT
cord-311730-189vax2m	77	10	rate	rate	NN
cord-311730-189vax2m	77	11	in	in	IN
cord-311730-189vax2m	77	12	chloroquine	chloroquine	NN
cord-311730-189vax2m	77	13	-	-	HYPH
cord-311730-189vax2m	77	14	treated	treat	VBN
cord-311730-189vax2m	77	15	patients	patient	NNS
cord-311730-189vax2m	77	16	compared	compare	VBN
cord-311730-189vax2m	77	17	to	to	IN
cord-311730-189vax2m	77	18	those	those	DT
cord-311730-189vax2m	77	19	receiving	receive	VBG
cord-311730-189vax2m	77	20	lopinavar	lopinavar	NNS
cord-311730-189vax2m	77	21	/	/	SYM
cord-311730-189vax2m	77	22	ritonavir	ritonavir	NNS
cord-311730-189vax2m	77	23	and	and	CC
cord-311730-189vax2m	77	24	duration	duration	NN
cord-311730-189vax2m	77	25	of	of	IN
cord-311730-189vax2m	77	26	hospitalization	hospitalization	NN
cord-311730-189vax2m	77	27	was	be	VBD
cord-311730-189vax2m	77	28	shorter	short	JJR
cord-311730-189vax2m	77	29	in	in	IN
cord-311730-189vax2m	77	30	the	the	DT
cord-311730-189vax2m	77	31	former	former	JJ
cord-311730-189vax2m	77	32	group	group	NN
cord-311730-189vax2m	77	33	as	as	RB
cord-311730-189vax2m	77	34	well	well	RB
cord-311730-189vax2m	77	35	.	.	.
cord-311730-189vax2m	78	1	Serious	serious	JJ
cord-311730-189vax2m	78	2	adverse	adverse	JJ
cord-311730-189vax2m	78	3	events	event	NNS
cord-311730-189vax2m	78	4	were	be	VBD
cord-311730-189vax2m	78	5	not	not	RB
cord-311730-189vax2m	78	6	reported	report	VBN
cord-311730-189vax2m	78	7	in	in	IN
cord-311730-189vax2m	78	8	either	either	DT
cord-311730-189vax2m	78	9	treatment	treatment	NN
cord-311730-189vax2m	78	10	group	group	NN
cord-311730-189vax2m	78	11	.	.	.
cord-311730-189vax2m	79	1	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-311730-189vax2m	79	2	was	be	VBD
cord-311730-189vax2m	79	3	developed	develop	VBN
cord-311730-189vax2m	79	4	and	and	CC
cord-311730-189vax2m	79	5	subsequently	subsequently	RB
cord-311730-189vax2m	79	6	approved	approve	VBD
cord-311730-189vax2m	79	7	for	for	IN
cord-311730-189vax2m	79	8	the	the	DT
cord-311730-189vax2m	79	9	treatment	treatment	NN
cord-311730-189vax2m	79	10	of	of	IN
cord-311730-189vax2m	79	11	malaria	malaria	NN
cord-311730-189vax2m	79	12	in	in	IN
cord-311730-189vax2m	79	13	1955	1955	CD
cord-311730-189vax2m	79	14	(	(	-LRB-
cord-311730-189vax2m	79	15	reviewed	review	VBN
cord-311730-189vax2m	79	16	in	in	IN
cord-311730-189vax2m	79	17	Al	Al	NNP
cord-311730-189vax2m	79	18	-	-	HYPH
cord-311730-189vax2m	79	19	Bari	Bari	NNP
cord-311730-189vax2m	79	20	;	;	:
cord-311730-189vax2m	79	21	[	[	-LRB-
cord-311730-189vax2m	79	22	16	16	CD
cord-311730-189vax2m	79	23	]	]	-RRB-
cord-311730-189vax2m	79	24	)	)	-RRB-
cord-311730-189vax2m	79	25	.	.	.
cord-311730-189vax2m	80	1	Like	like	IN
cord-311730-189vax2m	80	2	chloroquine	chloroquine	NN
cord-311730-189vax2m	80	3	,	,	,
cord-311730-189vax2m	80	4	but	but	CC
cord-311730-189vax2m	80	5	with	with	IN
cord-311730-189vax2m	80	6	a	a	DT
cord-311730-189vax2m	80	7	better	well	JJR
cord-311730-189vax2m	80	8	safety	safety	NN
cord-311730-189vax2m	80	9	profile	profile	NN
cord-311730-189vax2m	80	10	,	,	,
cord-311730-189vax2m	80	11	particularly	particularly	RB
cord-311730-189vax2m	80	12	with	with	IN
cord-311730-189vax2m	80	13	prolonged	prolong	VBN
cord-311730-189vax2m	80	14	use	use	NN
cord-311730-189vax2m	80	15	,	,	,
cord-311730-189vax2m	80	16	it	-PRON-	PRP
cord-311730-189vax2m	80	17	is	be	VBZ
cord-311730-189vax2m	80	18	included	include	VBN
cord-311730-189vax2m	80	19	on	on	IN
cord-311730-189vax2m	80	20	the	the	DT
cord-311730-189vax2m	80	21	World	World	NNP
cord-311730-189vax2m	80	22	Health	Health	NNP
cord-311730-189vax2m	80	23	Organization	Organization	NNP
cord-311730-189vax2m	80	24	's	's	POS
cord-311730-189vax2m	80	25	list	list	NN
cord-311730-189vax2m	80	26	of	of	IN
cord-311730-189vax2m	80	27	essential	essential	JJ
cord-311730-189vax2m	80	28	medications	medication	NNS
cord-311730-189vax2m	80	29	with	with	IN
cord-311730-189vax2m	80	30	indications	indication	NNS
cord-311730-189vax2m	80	31	for	for	IN
cord-311730-189vax2m	80	32	administration	administration	NN
cord-311730-189vax2m	80	33	that	that	WDT
cord-311730-189vax2m	80	34	have	have	VBP
cord-311730-189vax2m	80	35	expanded	expand	VBN
cord-311730-189vax2m	80	36	over	over	IN
cord-311730-189vax2m	80	37	the	the	DT
cord-311730-189vax2m	80	38	years	year	NNS
cord-311730-189vax2m	80	39	to	to	TO
cord-311730-189vax2m	80	40	include	include	VB
cord-311730-189vax2m	80	41	autoimmune	autoimmune	JJ
cord-311730-189vax2m	80	42	diseases	disease	NNS
cord-311730-189vax2m	80	43	such	such	JJ
cord-311730-189vax2m	80	44	as	as	IN
cord-311730-189vax2m	80	45	rheumatoid	rheumatoid	JJ
cord-311730-189vax2m	80	46	arthritis	arthritis	NN
cord-311730-189vax2m	80	47	,	,	,
cord-311730-189vax2m	80	48	Sjogren	Sjogren	NNP
cord-311730-189vax2m	80	49	's	's	POS
cord-311730-189vax2m	80	50	syndrome	syndrome	NN
cord-311730-189vax2m	80	51	,	,	,
cord-311730-189vax2m	80	52	systemic	systemic	JJ
cord-311730-189vax2m	80	53	lupus	lupus	NN
cord-311730-189vax2m	80	54	erythematosus	erythematosus	NN
cord-311730-189vax2m	80	55	and	and	CC
cord-311730-189vax2m	80	56	post	post	AFX
cord-311730-189vax2m	80	57	-	-	NNP
cord-311730-189vax2m	80	58	Lyme	Lyme	NNP
cord-311730-189vax2m	80	59	's	's	POS
cord-311730-189vax2m	80	60	disease	disease	NN
cord-311730-189vax2m	80	61	arthritis	arthritis	NN
cord-311730-189vax2m	80	62	(	(	-LRB-
cord-311730-189vax2m	80	63	reviewed	review	VBN
cord-311730-189vax2m	80	64	in	in	IN
cord-311730-189vax2m	80	65	Plantone	Plantone	NNP
cord-311730-189vax2m	80	66	;	;	:
cord-311730-189vax2m	80	67	[	[	-LRB-
cord-311730-189vax2m	80	68	17	17	CD
cord-311730-189vax2m	80	69	]	]	-RRB-
cord-311730-189vax2m	80	70	)	)	-RRB-
cord-311730-189vax2m	80	71	.	.	.
cord-311730-189vax2m	81	1	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-311730-189vax2m	81	2	exhibits	exhibit	VBZ
cord-311730-189vax2m	81	3	anti	anti	JJ
cord-311730-189vax2m	81	4	-	-	JJ
cord-311730-189vax2m	81	5	inflammatory	inflammatory	JJ
cord-311730-189vax2m	81	6	,	,	,
cord-311730-189vax2m	81	7	immunomodulating	immunomodulating	JJ
cord-311730-189vax2m	81	8	,	,	,
cord-311730-189vax2m	81	9	anti	anti	JJ
cord-311730-189vax2m	81	10	-	-	JJ
cord-311730-189vax2m	81	11	infective	infective	JJ
cord-311730-189vax2m	81	12	,	,	,
cord-311730-189vax2m	81	13	antithrombotic	antithrombotic	JJ
cord-311730-189vax2m	81	14	,	,	,
cord-311730-189vax2m	81	15	and	and	CC
cord-311730-189vax2m	81	16	metabolic	metabolic	JJ
cord-311730-189vax2m	81	17	effects	effect	NNS
cord-311730-189vax2m	81	18	.	.	.
cord-311730-189vax2m	82	1	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-311730-189vax2m	82	2	is	be	VBZ
cord-311730-189vax2m	82	3	absorbed	absorb	VBN
cord-311730-189vax2m	82	4	rapidly	rapidly	RB
cord-311730-189vax2m	82	5	after	after	IN
cord-311730-189vax2m	82	6	oral	oral	JJ
cord-311730-189vax2m	82	7	administration	administration	NN
cord-311730-189vax2m	82	8	,	,	,
cord-311730-189vax2m	82	9	metabolized	metabolize	VBN
cord-311730-189vax2m	82	10	by	by	IN
cord-311730-189vax2m	82	11	hepatic	hepatic	JJ
cord-311730-189vax2m	82	12	P450	p450	JJ
cord-311730-189vax2m	82	13	enzymes	enzyme	NNS
cord-311730-189vax2m	82	14	and	and	CC
cord-311730-189vax2m	82	15	cleared	clear	VBN
cord-311730-189vax2m	82	16	by	by	IN
cord-311730-189vax2m	82	17	the	the	DT
cord-311730-189vax2m	82	18	kidneys	kidney	NNS
cord-311730-189vax2m	82	19	.	.	.
cord-311730-189vax2m	83	1	As	as	IN
cord-311730-189vax2m	83	2	a	a	DT
cord-311730-189vax2m	83	3	result	result	NN
cord-311730-189vax2m	83	4	of	of	IN
cord-311730-189vax2m	83	5	its	-PRON-	PRP$
cord-311730-189vax2m	83	6	lipophilic	lipophilic	JJ
cord-311730-189vax2m	83	7	properties	property	NNS
cord-311730-189vax2m	83	8	and	and	CC
cord-311730-189vax2m	83	9	relatively	relatively	RB
cord-311730-189vax2m	83	10	high	high	JJ
cord-311730-189vax2m	83	11	pH	ph	NN
cord-311730-189vax2m	83	12	,	,	,
cord-311730-189vax2m	83	13	hydroxychloroquine	hydroxychloroquine	NNP
cord-311730-189vax2m	83	14	enters	enter	VBZ
cord-311730-189vax2m	83	15	cell	cell	NN
cord-311730-189vax2m	83	16	readily	readily	RB
cord-311730-189vax2m	83	17	and	and	CC
cord-311730-189vax2m	83	18	Torsades	Torsades	NNP
cord-311730-189vax2m	83	19	de	de	NNP
cord-311730-189vax2m	83	20	Pointes	Pointes	NNP
cord-311730-189vax2m	83	21	or	or	CC
cord-311730-189vax2m	83	22	"	"	``
cord-311730-189vax2m	83	23	twisting	twist	VBG
cord-311730-189vax2m	83	24	of	of	IN
cord-311730-189vax2m	83	25	the	the	DT
cord-311730-189vax2m	83	26	points	point	NNS
cord-311730-189vax2m	83	27	or	or	CC
cord-311730-189vax2m	83	28	peaks	peak	NNS
cord-311730-189vax2m	83	29	"	"	``
cord-311730-189vax2m	83	30	ventricular	ventricular	JJ
cord-311730-189vax2m	83	31	tachycardia	tachycardia	NN
cord-311730-189vax2m	83	32	occurs	occur	VBZ
cord-311730-189vax2m	83	33	in	in	IN
cord-311730-189vax2m	83	34	the	the	DT
cord-311730-189vax2m	83	35	setting	setting	NN
cord-311730-189vax2m	83	36	of	of	IN
cord-311730-189vax2m	83	37	a	a	DT
cord-311730-189vax2m	83	38	prolonged	prolonged	JJ
cord-311730-189vax2m	83	39	QTc	qtc	NN
cord-311730-189vax2m	83	40	interval	interval	NN
cord-311730-189vax2m	83	41	that	that	WDT
cord-311730-189vax2m	83	42	is	be	VBZ
cord-311730-189vax2m	83	43	either	either	CC
cord-311730-189vax2m	83	44	inherited	inherit	VBN
cord-311730-189vax2m	83	45	or	or	CC
cord-311730-189vax2m	83	46	acquired	acquire	VBN
cord-311730-189vax2m	83	47	or	or	CC
cord-311730-189vax2m	83	48	both	both	DT
cord-311730-189vax2m	83	49	.	.	.
cord-311730-189vax2m	84	1	Some	some	DT
cord-311730-189vax2m	84	2	individuals	individual	NNS
cord-311730-189vax2m	84	3	with	with	IN
cord-311730-189vax2m	84	4	familial	familial	JJ
cord-311730-189vax2m	84	5	long	long	JJ
cord-311730-189vax2m	84	6	QTc	qtc	NN
cord-311730-189vax2m	84	7	Syndrome	syndrome	NN
cord-311730-189vax2m	84	8	(	(	-LRB-
cord-311730-189vax2m	84	9	LQTS	LQTS	NNP
cord-311730-189vax2m	84	10	)	)	-RRB-
cord-311730-189vax2m	84	11	are	be	VBP
cord-311730-189vax2m	84	12	not	not	RB
cord-311730-189vax2m	84	13	aware	aware	JJ
cord-311730-189vax2m	84	14	of	of	IN
cord-311730-189vax2m	84	15	their	-PRON-	PRP$
cord-311730-189vax2m	84	16	condition	condition	NN
cord-311730-189vax2m	84	17	and	and	CC
cord-311730-189vax2m	84	18	symptoms	symptom	NNS
cord-311730-189vax2m	84	19	may	may	MD
cord-311730-189vax2m	84	20	not	not	RB
cord-311730-189vax2m	84	21	occur	occur	VB
cord-311730-189vax2m	84	22	until	until	IN
cord-311730-189vax2m	84	23	a	a	DT
cord-311730-189vax2m	84	24	medication	medication	NN
cord-311730-189vax2m	84	25	with	with	IN
cord-311730-189vax2m	84	26	QTc	qtc	NN
cord-311730-189vax2m	84	27	-	-	HYPH
cord-311730-189vax2m	84	28	prolonging	prolong	VBG
cord-311730-189vax2m	84	29	capabilities	capability	NNS
cord-311730-189vax2m	84	30	is	be	VBZ
cord-311730-189vax2m	84	31	administered	administer	VBN
cord-311730-189vax2m	84	32	.	.	.
cord-311730-189vax2m	85	1	The	the	DT
cord-311730-189vax2m	85	2	ventricular	ventricular	JJ
cord-311730-189vax2m	85	3	rate	rate	NN
cord-311730-189vax2m	85	4	is	be	VBZ
cord-311730-189vax2m	85	5	fast	fast	JJ
cord-311730-189vax2m	85	6	and	and	CC
cord-311730-189vax2m	85	7	almost	almost	RB
cord-311730-189vax2m	85	8	always	always	RB
cord-311730-189vax2m	85	9	causes	cause	VBZ
cord-311730-189vax2m	85	10	low	low	JJ
cord-311730-189vax2m	85	11	blood	blood	NN
cord-311730-189vax2m	85	12	pressure	pressure	NN
cord-311730-189vax2m	85	13	and	and	CC
cord-311730-189vax2m	85	14	hemodynamic	hemodynamic	JJ
cord-311730-189vax2m	85	15	compromise	compromise	NN
cord-311730-189vax2m	85	16	.	.	.
cord-311730-189vax2m	86	1	It	-PRON-	PRP
cord-311730-189vax2m	86	2	is	be	VBZ
cord-311730-189vax2m	86	3	a	a	DT
cord-311730-189vax2m	86	4	cause	cause	NN
cord-311730-189vax2m	86	5	of	of	IN
cord-311730-189vax2m	86	6	sudden	sudden	JJ
cord-311730-189vax2m	86	7	cardiac	cardiac	JJ
cord-311730-189vax2m	86	8	death	death	NN
cord-311730-189vax2m	86	9	accumulates	accumulate	VBZ
cord-311730-189vax2m	86	10	within	within	IN
cord-311730-189vax2m	86	11	lysosomes	lysosome	NNS
cord-311730-189vax2m	86	12	.	.	.
cord-311730-189vax2m	87	1	There	there	EX
cord-311730-189vax2m	87	2	is	be	VBZ
cord-311730-189vax2m	87	3	a	a	DT
cord-311730-189vax2m	87	4	resulting	result	VBG
cord-311730-189vax2m	87	5	increase	increase	NN
cord-311730-189vax2m	87	6	in	in	IN
cord-311730-189vax2m	87	7	pH	ph	NN
cord-311730-189vax2m	87	8	from	from	IN
cord-311730-189vax2m	87	9	4	4	CD
cord-311730-189vax2m	87	10	to	to	IN
cord-311730-189vax2m	87	11	6	6	CD
cord-311730-189vax2m	87	12	that	that	WDT
cord-311730-189vax2m	87	13	attenuates	attenuate	VBZ
cord-311730-189vax2m	87	14	glycosylation	glycosylation	NN
cord-311730-189vax2m	87	15	and	and	CC
cord-311730-189vax2m	87	16	release	release	NN
cord-311730-189vax2m	87	17	of	of	IN
cord-311730-189vax2m	87	18	antigenic	antigenic	JJ
cord-311730-189vax2m	87	19	proteins	protein	NNS
cord-311730-189vax2m	87	20	,	,	,
cord-311730-189vax2m	87	21	interference	interference	NN
cord-311730-189vax2m	87	22	of	of	IN
cord-311730-189vax2m	87	23	lysosomal	lysosomal	JJ
cord-311730-189vax2m	87	24	acidification	acidification	NN
cord-311730-189vax2m	87	25	,	,	,
cord-311730-189vax2m	87	26	decreased	decrease	VBD
cord-311730-189vax2m	87	27	macrophage	macrophage	NN
cord-311730-189vax2m	87	28	cytokine	cytokine	NN
cord-311730-189vax2m	87	29	production	production	NN
cord-311730-189vax2m	87	30	to	to	TO
cord-311730-189vax2m	87	31	include	include	VB
cord-311730-189vax2m	87	32	interleukins	interleukin	NNS
cord-311730-189vax2m	87	33	and	and	CC
cord-311730-189vax2m	87	34	tumor	tumor	NN
cord-311730-189vax2m	87	35	necrosis	necrosis	NN
cord-311730-189vax2m	87	36	factor	factor	NN
cord-311730-189vax2m	87	37	(	(	-LRB-
cord-311730-189vax2m	87	38	TNF)-α	TNF)-α	NNP
cord-311730-189vax2m	87	39	,	,	,
cord-311730-189vax2m	87	40	antagonist	antagonist	NN
cord-311730-189vax2m	87	41	effects	effect	NNS
cord-311730-189vax2m	87	42	on	on	IN
cord-311730-189vax2m	87	43	prostaglandins	prostaglandin	NNS
cord-311730-189vax2m	87	44	,	,	,
cord-311730-189vax2m	87	45	binding	bind	VBG
cord-311730-189vax2m	87	46	and	and	CC
cord-311730-189vax2m	87	47	stabilizing	stabilizing	NN
cord-311730-189vax2m	87	48	of	of	IN
cord-311730-189vax2m	87	49	nucleic	nucleic	JJ
cord-311730-189vax2m	87	50	acids	acid	NNS
cord-311730-189vax2m	87	51	,	,	,
cord-311730-189vax2m	87	52	inhibition	inhibition	NN
cord-311730-189vax2m	87	53	of	of	IN
cord-311730-189vax2m	87	54	T	t	NN
cord-311730-189vax2m	87	55	and	and	CC
cord-311730-189vax2m	87	56	B	b	NN
cord-311730-189vax2m	87	57	-	-	HYPH
cord-311730-189vax2m	87	58	cell	cell	NN
cord-311730-189vax2m	87	59	signaling	signaling	NN
cord-311730-189vax2m	87	60	,	,	,
cord-311730-189vax2m	87	61	inhibition	inhibition	NN
cord-311730-189vax2m	87	62	of	of	IN
cord-311730-189vax2m	87	63	matrix	matrix	NN
cord-311730-189vax2m	87	64	metalloproteinases	metalloproteinase	NNS
cord-311730-189vax2m	87	65	[	[	-LRB-
cord-311730-189vax2m	87	66	18	18	CD
cord-311730-189vax2m	87	67	]	]	-RRB-
cord-311730-189vax2m	87	68	[	[	-LRB-
cord-311730-189vax2m	87	69	19	19	CD
cord-311730-189vax2m	87	70	]	]	-RRB-
cord-311730-189vax2m	87	71	[	[	-LRB-
cord-311730-189vax2m	87	72	20	20	CD
cord-311730-189vax2m	87	73	]	]	-RRB-
cord-311730-189vax2m	87	74	,	,	,
cord-311730-189vax2m	87	75	chemotaxis	chemotaxis	NN
cord-311730-189vax2m	87	76	,	,	,
cord-311730-189vax2m	87	77	superoxide	superoxide	NN
cord-311730-189vax2m	87	78	production	production	NN
cord-311730-189vax2m	87	79	and	and	CC
cord-311730-189vax2m	87	80	phagocytosis	phagocytosis	NN
cord-311730-189vax2m	87	81	of	of	IN
cord-311730-189vax2m	87	82	neutrophils	neutrophil	NNS
cord-311730-189vax2m	87	83	,	,	,
cord-311730-189vax2m	87	84	a	a	DT
cord-311730-189vax2m	87	85	reduction	reduction	NN
cord-311730-189vax2m	87	86	in	in	IN
cord-311730-189vax2m	87	87	Toll	Toll	NNP
cord-311730-189vax2m	87	88	-	-	HYPH
cord-311730-189vax2m	87	89	like	like	JJ
cord-311730-189vax2m	87	90	receptor	receptor	NN
cord-311730-189vax2m	87	91	signaling	signaling	NN
cord-311730-189vax2m	87	92	and	and	CC
cord-311730-189vax2m	87	93	attenuated	attenuated	JJ
cord-311730-189vax2m	87	94	activation	activation	NN
cord-311730-189vax2m	87	95	of	of	IN
cord-311730-189vax2m	87	96	dendritic	dendritic	JJ
cord-311730-189vax2m	87	97	cells	cell	NNS
cord-311730-189vax2m	87	98	.	.	.
cord-311730-189vax2m	88	1	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-311730-189vax2m	88	2	has	have	VBZ
cord-311730-189vax2m	88	3	also	also	RB
cord-311730-189vax2m	88	4	been	be	VBN
cord-311730-189vax2m	88	5	shown	show	VBN
cord-311730-189vax2m	88	6	to	to	TO
cord-311730-189vax2m	88	7	bind	bind	VB
cord-311730-189vax2m	88	8	cell	cell	NN
cord-311730-189vax2m	88	9	surface	surface	NN
cord-311730-189vax2m	88	10	sialic	sialic	NN
cord-311730-189vax2m	88	11	acid	acid	NN
cord-311730-189vax2m	88	12	and	and	CC
cord-311730-189vax2m	88	13	gangliosides	ganglioside	NNS
cord-311730-189vax2m	88	14	with	with	IN
cord-311730-189vax2m	88	15	high	high	JJ
cord-311730-189vax2m	88	16	affinity	affinity	NN
cord-311730-189vax2m	88	17	,	,	,
cord-311730-189vax2m	88	18	thereby	thereby	RB
cord-311730-189vax2m	88	19	impairing	impair	VBG
cord-311730-189vax2m	88	20	SARS	SARS	NNP
cord-311730-189vax2m	88	21	-	-	HYPH
cord-311730-189vax2m	88	22	CoV-2	CoV-2	NNP
cord-311730-189vax2m	88	23	spike	spike	NN
cord-311730-189vax2m	88	24	protein	protein	NN
cord-311730-189vax2m	88	25	recognition	recognition	NN
cord-311730-189vax2m	88	26	and	and	CC
cord-311730-189vax2m	88	27	binding	bind	VBG
cord-311730-189vax2m	88	28	to	to	TO
cord-311730-189vax2m	88	29	host	host	VB
cord-311730-189vax2m	88	30	cell	cell	NN
cord-311730-189vax2m	88	31	angiotensin	angiotensin	NN
cord-311730-189vax2m	88	32	converting	convert	VBG
cord-311730-189vax2m	88	33	enzyme	enzyme	NN
cord-311730-189vax2m	88	34	(	(	-LRB-
cord-311730-189vax2m	88	35	ACE)-2	ace)-2	NN
cord-311730-189vax2m	88	36	receptors	receptor	NNS
cord-311730-189vax2m	88	37	[	[	-LRB-
cord-311730-189vax2m	88	38	21	21	CD
cord-311730-189vax2m	88	39	]	]	-RRB-
cord-311730-189vax2m	88	40	.	.	.
cord-311730-189vax2m	89	1	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-311730-189vax2m	89	2	's	's	POS
cord-311730-189vax2m	89	3	blockade	blockade	NN
cord-311730-189vax2m	89	4	of	of	IN
cord-311730-189vax2m	89	5	TNF	TNF	NNP
cord-311730-189vax2m	89	6	-	-	HYPH
cord-311730-189vax2m	89	7	α	α	NNP
cord-311730-189vax2m	89	8	has	have	VBZ
cord-311730-189vax2m	89	9	been	be	VBN
cord-311730-189vax2m	89	10	associated	associate	VBN
cord-311730-189vax2m	89	11	with	with	IN
cord-311730-189vax2m	89	12	a	a	DT
cord-311730-189vax2m	89	13	reduction	reduction	NN
cord-311730-189vax2m	89	14	of	of	IN
cord-311730-189vax2m	89	15	atherosclerotic	atherosclerotic	JJ
cord-311730-189vax2m	89	16	cardiovascular	cardiovascular	JJ
cord-311730-189vax2m	89	17	disease	disease	NN
cord-311730-189vax2m	89	18	-	-	HYPH
cord-311730-189vax2m	89	19	associated	associate	VBN
cord-311730-189vax2m	89	20	events	event	NNS
cord-311730-189vax2m	89	21	among	among	IN
cord-311730-189vax2m	89	22	patients	patient	NNS
cord-311730-189vax2m	89	23	with	with	IN
cord-311730-189vax2m	89	24	autoimmune	autoimmune	JJ
cord-311730-189vax2m	89	25	rheumatologic	rheumatologic	JJ
cord-311730-189vax2m	89	26	disease	disease	NN
cord-311730-189vax2m	89	27	[	[	-LRB-
cord-311730-189vax2m	89	28	22	22	CD
cord-311730-189vax2m	89	29	]	]	-RRB-
cord-311730-189vax2m	89	30	(	(	-LRB-
cord-311730-189vax2m	89	31	age	age	NN
cord-311730-189vax2m	89	32	adjusted	adjust	VBN
cord-311730-189vax2m	89	33	rate	rate	NN
cord-311730-189vax2m	89	34	ratio	ratio	NN
cord-311730-189vax2m	89	35	0.46	0.46	CD
cord-311730-189vax2m	89	36	,	,	,
cord-311730-189vax2m	89	37	95	95	CD
cord-311730-189vax2m	89	38	%	%	NN
cord-311730-189vax2m	89	39	CI	CI	NNP
cord-311730-189vax2m	89	40	0.25	0.25	CD
cord-311730-189vax2m	89	41	-0.85	-0.85	CD
cord-311730-189vax2m	89	42	)	)	-RRB-
cord-311730-189vax2m	89	43	.	.	.
cord-311730-189vax2m	90	1	Interleukin	Interleukin	NNP
cord-311730-189vax2m	90	2	(	(	-LRB-
cord-311730-189vax2m	90	3	IL)-1	IL)-1	``
cord-311730-189vax2m	90	4	inhibition	inhibition	NN
cord-311730-189vax2m	90	5	has	have	VBZ
cord-311730-189vax2m	90	6	also	also	RB
cord-311730-189vax2m	90	7	been	be	VBN
cord-311730-189vax2m	90	8	shown	show	VBN
cord-311730-189vax2m	90	9	to	to	TO
cord-311730-189vax2m	90	10	reduce	reduce	VB
cord-311730-189vax2m	90	11	cardiovascular	cardiovascular	JJ
cord-311730-189vax2m	90	12	events	event	NNS
cord-311730-189vax2m	90	13	(	(	-LRB-
cord-311730-189vax2m	90	14	reviewed	review	VBN
cord-311730-189vax2m	90	15	in	in	IN
cord-311730-189vax2m	90	16	Ali	Ali	NNP
cord-311730-189vax2m	90	17	and	and	CC
cord-311730-189vax2m	90	18	Becker	Becker	NNP
cord-311730-189vax2m	90	19	[	[	-LRB-
cord-311730-189vax2m	90	20	23	23	CD
cord-311730-189vax2m	90	21	,	,	,
cord-311730-189vax2m	90	22	24	24	CD
cord-311730-189vax2m	90	23	]	]	-RRB-
cord-311730-189vax2m	90	24	)	)	-RRB-
cord-311730-189vax2m	90	25	and	and	CC
cord-311730-189vax2m	90	26	reduced	reduce	VBN
cord-311730-189vax2m	90	27	synthesis	synthesis	NN
cord-311730-189vax2m	90	28	of	of	IN
cord-311730-189vax2m	90	29	MMP-9	MMP-9	NNP
cord-311730-189vax2m	90	30	may	may	MD
cord-311730-189vax2m	90	31	lessen	lessen	VB
cord-311730-189vax2m	90	32	atherosclerotic	atherosclerotic	JJ
cord-311730-189vax2m	90	33	plaque	plaque	NN
cord-311730-189vax2m	90	34	disruption	disruption	NN
cord-311730-189vax2m	90	35	.	.	.
cord-311730-189vax2m	91	1	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-311730-189vax2m	91	2	's	's	POS
cord-311730-189vax2m	91	3	ability	ability	NN
cord-311730-189vax2m	91	4	to	to	TO
cord-311730-189vax2m	91	5	lower	lower	VB
cord-311730-189vax2m	91	6	cholesterol	cholesterol	NN
cord-311730-189vax2m	91	7	and	and	CC
cord-311730-189vax2m	91	8	hemoglobin	hemoglobin	NN
cord-311730-189vax2m	91	9	AIC	AIC	NNP
cord-311730-189vax2m	91	10	in	in	IN
cord-311730-189vax2m	91	11	diabetes	diabetes	NN
cord-311730-189vax2m	91	12	may	may	MD
cord-311730-189vax2m	91	13	not	not	RB
cord-311730-189vax2m	91	14	contribute	contribute	VB
cord-311730-189vax2m	91	15	to	to	TO
cord-311730-189vax2m	91	16	benefit	benefit	VB
cord-311730-189vax2m	91	17	with	with	IN
cord-311730-189vax2m	91	18	short	short	JJ
cord-311730-189vax2m	91	19	courses	course	NNS
cord-311730-189vax2m	91	20	of	of	IN
cord-311730-189vax2m	91	21	treatment	treatment	NN
cord-311730-189vax2m	91	22	[	[	-LRB-
cord-311730-189vax2m	91	23	25	25	CD
cord-311730-189vax2m	91	24	]	]	-RRB-
cord-311730-189vax2m	91	25	.	.	.
cord-311730-189vax2m	92	1	However	however	RB
cord-311730-189vax2m	92	2	,	,	,
cord-311730-189vax2m	92	3	if	if	IN
cord-311730-189vax2m	92	4	ongoing	ongoing	JJ
cord-311730-189vax2m	92	5	studies	study	NNS
cord-311730-189vax2m	92	6	show	show	VBP
cord-311730-189vax2m	92	7	that	that	IN
cord-311730-189vax2m	92	8	it	-PRON-	PRP
cord-311730-189vax2m	92	9	offers	offer	VBZ
cord-311730-189vax2m	92	10	protection	protection	NN
cord-311730-189vax2m	92	11	against	against	IN
cord-311730-189vax2m	92	12	SARS	SARS	NNP
cord-311730-189vax2m	92	13	-	-	HYPH
cord-311730-189vax2m	92	14	CoV-2	CoV-2	NNP
cord-311730-189vax2m	92	15	infection	infection	NN
cord-311730-189vax2m	92	16	,	,	,
cord-311730-189vax2m	92	17	then	then	RB
cord-311730-189vax2m	92	18	longer	long	JJR
cord-311730-189vax2m	92	19	courses	course	NNS
cord-311730-189vax2m	92	20	of	of	IN
cord-311730-189vax2m	92	21	drug	drug	NN
cord-311730-189vax2m	92	22	administration	administration	NN
cord-311730-189vax2m	92	23	may	may	MD
cord-311730-189vax2m	92	24	be	be	VB
cord-311730-189vax2m	92	25	recommended	recommend	VBN
cord-311730-189vax2m	92	26	.	.	.
cord-311730-189vax2m	93	1	The	the	DT
cord-311730-189vax2m	93	2	platelet	platelet	NN
cord-311730-189vax2m	93	3	inhibiting	inhibit	VBG
cord-311730-189vax2m	93	4	properties	property	NNS
cord-311730-189vax2m	93	5	of	of	IN
cord-311730-189vax2m	93	6	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	93	7	,	,	,
cord-311730-189vax2m	93	8	either	either	CC
cord-311730-189vax2m	93	9	alone	alone	RB
cord-311730-189vax2m	93	10	or	or	CC
cord-311730-189vax2m	93	11	in	in	IN
cord-311730-189vax2m	93	12	combination	combination	NN
cord-311730-189vax2m	93	13	with	with	IN
cord-311730-189vax2m	93	14	aspirin	aspirin	NN
cord-311730-189vax2m	93	15	[	[	-LRB-
cord-311730-189vax2m	93	16	26	26	CD
cord-311730-189vax2m	93	17	]	]	-RRB-
cord-311730-189vax2m	93	18	may	may	MD
cord-311730-189vax2m	93	19	be	be	VB
cord-311730-189vax2m	93	20	attractive	attractive	JJ
cord-311730-189vax2m	93	21	with	with	IN
cord-311730-189vax2m	93	22	either	either	CC
cord-311730-189vax2m	93	23	short	short	JJ
cord-311730-189vax2m	93	24	or	or	CC
cord-311730-189vax2m	93	25	more	more	RBR
cord-311730-189vax2m	93	26	prolonged	prolonged	JJ
cord-311730-189vax2m	93	27	courses	course	NNS
cord-311730-189vax2m	93	28	of	of	IN
cord-311730-189vax2m	93	29	treatment	treatment	NN
cord-311730-189vax2m	93	30	[	[	-LRB-
cord-311730-189vax2m	93	31	27	27	CD
cord-311730-189vax2m	93	32	]	]	-RRB-
cord-311730-189vax2m	93	33	.	.	.
cord-311730-189vax2m	94	1	Chatre	Chatre	NNP
cord-311730-189vax2m	94	2	et	et	NNP
cord-311730-189vax2m	94	3	al	al	NNP
cord-311730-189vax2m	94	4	.	.	.
cord-311730-189vax2m	95	1	[	[	-LRB-
cord-311730-189vax2m	95	2	28	28	CD
cord-311730-189vax2m	95	3	]	]	-RRB-
cord-311730-189vax2m	95	4	performed	perform	VBD
cord-311730-189vax2m	95	5	a	a	DT
cord-311730-189vax2m	95	6	systematic	systematic	JJ
cord-311730-189vax2m	95	7	review	review	NN
cord-311730-189vax2m	95	8	of	of	IN
cord-311730-189vax2m	95	9	cardiac	cardiac	JJ
cord-311730-189vax2m	95	10	complications	complication	NNS
cord-311730-189vax2m	95	11	attributable	attributable	JJ
cord-311730-189vax2m	95	12	to	to	IN
cord-311730-189vax2m	95	13	hydroxychloroquine	hydroxychloroquine	NNP
cord-311730-189vax2m	95	14	(	(	-LRB-
cord-311730-189vax2m	95	15	and	and	CC
cord-311730-189vax2m	95	16	chloroquine	chloroquine	NN
cord-311730-189vax2m	95	17	)	)	-RRB-
cord-311730-189vax2m	95	18	.	.	.
cord-311730-189vax2m	96	1	There	there	EX
cord-311730-189vax2m	96	2	were	be	VBD
cord-311730-189vax2m	96	3	a	a	DT
cord-311730-189vax2m	96	4	total	total	NN
cord-311730-189vax2m	96	5	of	of	IN
cord-311730-189vax2m	96	6	127	127	CD
cord-311730-189vax2m	96	7	patients	patient	NNS
cord-311730-189vax2m	96	8	from	from	IN
cord-311730-189vax2m	96	9	individual	individual	JJ
cord-311730-189vax2m	96	10	case	case	NN
cord-311730-189vax2m	96	11	reports	report	NNS
cord-311730-189vax2m	96	12	and	and	CC
cord-311730-189vax2m	96	13	case	case	NN
cord-311730-189vax2m	96	14	series	series	NN
cord-311730-189vax2m	96	15	.	.	.
cord-311730-189vax2m	97	1	The	the	DT
cord-311730-189vax2m	97	2	median	median	JJ
cord-311730-189vax2m	97	3	duration	duration	NN
cord-311730-189vax2m	97	4	of	of	IN
cord-311730-189vax2m	97	5	treatment	treatment	NN
cord-311730-189vax2m	97	6	was	be	VBD
cord-311730-189vax2m	97	7	7	7	CD
cord-311730-189vax2m	97	8	years	year	NNS
cord-311730-189vax2m	97	9	,	,	,
cord-311730-189vax2m	97	10	with	with	IN
cord-311730-189vax2m	97	11	a	a	DT
cord-311730-189vax2m	97	12	range	range	NN
cord-311730-189vax2m	97	13	from	from	IN
cord-311730-189vax2m	97	14	3	3	CD
cord-311730-189vax2m	97	15	days	day	NNS
cord-311730-189vax2m	97	16	to	to	IN
cord-311730-189vax2m	97	17	35	35	CD
cord-311730-189vax2m	97	18	years	year	NNS
cord-311730-189vax2m	97	19	.	.	.
cord-311730-189vax2m	98	1	The	the	DT
cord-311730-189vax2m	98	2	cumulative	cumulative	JJ
cord-311730-189vax2m	98	3	doses	dose	NNS
cord-311730-189vax2m	98	4	were	be	VBD
cord-311730-189vax2m	98	5	1000	1000	CD
cord-311730-189vax2m	98	6	g	g	NN
cord-311730-189vax2m	98	7	or	or	CC
cord-311730-189vax2m	98	8	more	more	JJR
cord-311730-189vax2m	98	9	.	.	.
cord-311730-189vax2m	99	1	The	the	DT
cord-311730-189vax2m	99	2	most	most	JJS
cord-311730-189vax2m	99	3	comment	comment	NN
cord-311730-189vax2m	99	4	adverse	adverse	JJ
cord-311730-189vax2m	99	5	cardiovascular	cardiovascular	JJ
cord-311730-189vax2m	99	6	effect	effect	NN
cord-311730-189vax2m	99	7	was	be	VBD
cord-311730-189vax2m	99	8	AV	av	NN
cord-311730-189vax2m	99	9	conduction	conduction	NN
cord-311730-189vax2m	99	10	abnormalities	abnormality	NNS
cord-311730-189vax2m	99	11	(	(	-LRB-
cord-311730-189vax2m	99	12	85	85	CD
cord-311730-189vax2m	99	13	%	%	NN
cord-311730-189vax2m	99	14	of	of	IN
cord-311730-189vax2m	99	15	patients	patient	NNS
cord-311730-189vax2m	99	16	)	)	-RRB-
cord-311730-189vax2m	99	17	.	.	.
cord-311730-189vax2m	100	1	Reduced	reduce	VBN
cord-311730-189vax2m	100	2	ventricular	ventricular	JJ
cord-311730-189vax2m	100	3	performance	performance	NN
cord-311730-189vax2m	100	4	was	be	VBD
cord-311730-189vax2m	100	5	observed	observe	VBN
cord-311730-189vax2m	100	6	as	as	IN
cord-311730-189vax2m	100	7	was	be	VBD
cord-311730-189vax2m	100	8	heart	heart	NN
cord-311730-189vax2m	100	9	failure	failure	NN
cord-311730-189vax2m	100	10	with	with	IN
cord-311730-189vax2m	100	11	the	the	DT
cord-311730-189vax2m	100	12	former	former	JJ
cord-311730-189vax2m	100	13	recovering	recovering	NN
cord-311730-189vax2m	100	14	in	in	IN
cord-311730-189vax2m	100	15	nearly	nearly	RB
cord-311730-189vax2m	100	16	half	half	NN
cord-311730-189vax2m	100	17	of	of	IN
cord-311730-189vax2m	100	18	patients	patient	NNS
cord-311730-189vax2m	100	19	after	after	IN
cord-311730-189vax2m	100	20	drug	drug	NN
cord-311730-189vax2m	100	21	withdrawal	withdrawal	NN
cord-311730-189vax2m	100	22	.	.	.
cord-311730-189vax2m	101	1	It	-PRON-	PRP
cord-311730-189vax2m	101	2	is	be	VBZ
cord-311730-189vax2m	101	3	important	important	JJ
cord-311730-189vax2m	101	4	to	to	TO
cord-311730-189vax2m	101	5	acknowledge	acknowledge	VB
cord-311730-189vax2m	101	6	that	that	DT
cord-311730-189vax2m	101	7	may	may	NNP
cord-311730-189vax2m	101	8	of	of	IN
cord-311730-189vax2m	101	9	the	the	DT
cord-311730-189vax2m	101	10	patients	patient	NNS
cord-311730-189vax2m	101	11	included	include	VBN
cord-311730-189vax2m	101	12	in	in	IN
cord-311730-189vax2m	101	13	the	the	DT
cord-311730-189vax2m	101	14	systematic	systematic	JJ
cord-311730-189vax2m	101	15	review	review	NN
cord-311730-189vax2m	101	16	were	be	VBD
cord-311730-189vax2m	101	17	being	be	VBG
cord-311730-189vax2m	101	18	treated	treat	VBN
cord-311730-189vax2m	101	19	for	for	IN
cord-311730-189vax2m	101	20	autoimmune	autoimmune	JJ
cord-311730-189vax2m	101	21	disease	disease	NN
cord-311730-189vax2m	101	22	.	.	.
cord-311730-189vax2m	102	1	The	the	DT
cord-311730-189vax2m	102	2	adverse	adverse	JJ
cord-311730-189vax2m	102	3	effects	effect	NNS
cord-311730-189vax2m	102	4	associated	associate	VBN
cord-311730-189vax2m	102	5	with	with	IN
cord-311730-189vax2m	102	6	taking	take	VBG
cord-311730-189vax2m	102	7	hydroxychloroquine	hydroxychloroquine	NNP
cord-311730-189vax2m	102	8	are	be	VBP
cord-311730-189vax2m	102	9	similar	similar	JJ
cord-311730-189vax2m	102	10	to	to	IN
cord-311730-189vax2m	102	11	those	those	DT
cord-311730-189vax2m	102	12	observed	observe	VBN
cord-311730-189vax2m	102	13	with	with	IN
cord-311730-189vax2m	102	14	chloroquine	chloroquine	NN
cord-311730-189vax2m	102	15	and	and	CC
cord-311730-189vax2m	102	16	include	include	VBP
cord-311730-189vax2m	102	17	nausea	nausea	NN
cord-311730-189vax2m	102	18	,	,	,
cord-311730-189vax2m	102	19	vomiting	vomiting	NN
cord-311730-189vax2m	102	20	,	,	,
cord-311730-189vax2m	102	21	diarrhea	diarrhea	NN
cord-311730-189vax2m	102	22	,	,	,
cord-311730-189vax2m	102	23	AV	av	NN
cord-311730-189vax2m	102	24	conduction	conduction	NN
cord-311730-189vax2m	102	25	defects	defect	NNS
cord-311730-189vax2m	102	26	,	,	,
cord-311730-189vax2m	102	27	a	a	DT
cord-311730-189vax2m	102	28	prolonged	prolonged	JJ
cord-311730-189vax2m	102	29	QTc	qtc	NN
cord-311730-189vax2m	102	30	interval	interval	NN
cord-311730-189vax2m	102	31	with	with	IN
cord-311730-189vax2m	102	32	torsades	torsades	NNP
cord-311730-189vax2m	102	33	de	de	NNP
cord-311730-189vax2m	102	34	pointe	pointe	NNP
cord-311730-189vax2m	102	35	ventricular	ventricular	JJ
cord-311730-189vax2m	102	36	tachycardia	tachycardia	NN
cord-311730-189vax2m	102	37	,	,	,
cord-311730-189vax2m	102	38	hypokalemia	hypokalemia	NN
cord-311730-189vax2m	102	39	,	,	,
cord-311730-189vax2m	102	40	hypotension	hypotension	NN
cord-311730-189vax2m	102	41	and	and	CC
cord-311730-189vax2m	102	42	circulatory	circulatory	JJ
cord-311730-189vax2m	102	43	collapse	collapse	NN
cord-311730-189vax2m	102	44	.	.	.
cord-311730-189vax2m	103	1	The	the	DT
cord-311730-189vax2m	103	2	hemodynamic	hemodynamic	JJ
cord-311730-189vax2m	103	3	complications	complication	NNS
cord-311730-189vax2m	103	4	are	be	VBP
cord-311730-189vax2m	103	5	much	much	RB
cord-311730-189vax2m	103	6	more	more	RBR
cord-311730-189vax2m	103	7	likely	likely	JJ
cord-311730-189vax2m	103	8	to	to	TO
cord-311730-189vax2m	103	9	occur	occur	VB
cord-311730-189vax2m	103	10	with	with	IN
cord-311730-189vax2m	103	11	excessively	excessively	RB
cord-311730-189vax2m	103	12	large	large	JJ
cord-311730-189vax2m	103	13	doses	dose	NNS
cord-311730-189vax2m	103	14	;	;	:
cord-311730-189vax2m	103	15	however	however	RB
cord-311730-189vax2m	103	16	,	,	,
cord-311730-189vax2m	103	17	QTc	QTc	NNP
cord-311730-189vax2m	103	18	prolongation	prolongation	NN
cord-311730-189vax2m	103	19	can	can	MD
cord-311730-189vax2m	103	20	be	be	VB
cord-311730-189vax2m	103	21	seen	see	VBN
cord-311730-189vax2m	103	22	with	with	IN
cord-311730-189vax2m	103	23	standard	standard	JJ
cord-311730-189vax2m	103	24	recommended	recommend	VBN
cord-311730-189vax2m	103	25	doses	dose	NNS
cord-311730-189vax2m	103	26	even	even	RB
cord-311730-189vax2m	103	27	in	in	IN
cord-311730-189vax2m	103	28	the	the	DT
cord-311730-189vax2m	103	29	absence	absence	NN
cord-311730-189vax2m	103	30	of	of	IN
cord-311730-189vax2m	103	31	concomitant	concomitant	JJ
cord-311730-189vax2m	103	32	electrolyte	electrolyte	JJ
cord-311730-189vax2m	103	33	abnormalities	abnormality	NNS
cord-311730-189vax2m	103	34	(	(	-LRB-
cord-311730-189vax2m	103	35	low	low	JJ
cord-311730-189vax2m	103	36	potassium	potassium	NN
cord-311730-189vax2m	103	37	,	,	,
cord-311730-189vax2m	103	38	magnesium	magnesium	NN
cord-311730-189vax2m	103	39	or	or	CC
cord-311730-189vax2m	103	40	calcium	calcium	NN
cord-311730-189vax2m	103	41	)	)	-RRB-
cord-311730-189vax2m	103	42	.	.	.
cord-311730-189vax2m	104	1	Drug	drug	NN
cord-311730-189vax2m	104	2	-	-	HYPH
cord-311730-189vax2m	104	3	drug	drug	NN
cord-311730-189vax2m	104	4	interactions	interaction	NNS
cord-311730-189vax2m	104	5	must	must	MD
cord-311730-189vax2m	104	6	be	be	VB
cord-311730-189vax2m	104	7	considered	consider	VBN
cord-311730-189vax2m	104	8	in	in	IN
cord-311730-189vax2m	104	9	patients	patient	NNS
cord-311730-189vax2m	104	10	taking	take	VBG
cord-311730-189vax2m	104	11	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	104	12	and	and	CC
cord-311730-189vax2m	104	13	include	include	VBP
cord-311730-189vax2m	104	14	digoxin	digoxin	NN
cord-311730-189vax2m	104	15	(	(	-LRB-
cord-311730-189vax2m	104	16	increased	increase	VBN
cord-311730-189vax2m	104	17	levels	level	NNS
cord-311730-189vax2m	104	18	)	)	-RRB-
cord-311730-189vax2m	104	19	,	,	,
cord-311730-189vax2m	104	20	insulin	insulin	NN
cord-311730-189vax2m	104	21	and	and	CC
cord-311730-189vax2m	104	22	oral	oral	JJ
cord-311730-189vax2m	104	23	hypoglycemic	hypoglycemic	JJ
cord-311730-189vax2m	104	24	agents	agent	NNS
cord-311730-189vax2m	104	25	(	(	-LRB-
cord-311730-189vax2m	104	26	heighted	heighted	JJ
cord-311730-189vax2m	104	27	responses	response	NNS
cord-311730-189vax2m	104	28	and	and	CC
cord-311730-189vax2m	104	29	hypoglycemia	hypoglycemia	NN
cord-311730-189vax2m	104	30	)	)	-RRB-
cord-311730-189vax2m	104	31	,	,	,
cord-311730-189vax2m	104	32	antiepileptic	antiepileptic	JJ
cord-311730-189vax2m	104	33	drugs	drug	NNS
cord-311730-189vax2m	104	34	,	,	,
cord-311730-189vax2m	104	35	methotrexate	methotrexate	NNP
cord-311730-189vax2m	104	36	,	,	,
cord-311730-189vax2m	104	37	cyclosporine	cyclosporine	NN
cord-311730-189vax2m	104	38	and	and	CC
cord-311730-189vax2m	104	39	drugs	drug	NNS
cord-311730-189vax2m	104	40	that	that	WDT
cord-311730-189vax2m	104	41	prolong	prolong	VBP
cord-311730-189vax2m	104	42	the	the	DT
cord-311730-189vax2m	104	43	QTc	qtc	NN
cord-311730-189vax2m	104	44	.	.	.
cord-311730-189vax2m	105	1	The	the	DT
cord-311730-189vax2m	105	2	antiviral	antiviral	JJ
cord-311730-189vax2m	105	3	properties	property	NNS
cord-311730-189vax2m	105	4	of	of	IN
cord-311730-189vax2m	105	5	hydroxychloroquine	hydroxychloroquine	NNP
cord-311730-189vax2m	105	6	have	have	VBP
cord-311730-189vax2m	105	7	been	be	VBN
cord-311730-189vax2m	105	8	summarized	summarize	VBN
cord-311730-189vax2m	105	9	and	and	CC
cord-311730-189vax2m	105	10	provide	provide	VB
cord-311730-189vax2m	105	11	a	a	DT
cord-311730-189vax2m	105	12	foundation	foundation	NN
cord-311730-189vax2m	105	13	for	for	IN
cord-311730-189vax2m	105	14	additional	additional	JJ
cord-311730-189vax2m	105	15	formative	formative	JJ
cord-311730-189vax2m	105	16	discussion	discussion	NN
cord-311730-189vax2m	105	17	.	.	.
cord-311730-189vax2m	106	1	Yao	Yao	NNP
cord-311730-189vax2m	106	2	and	and	CC
cord-311730-189vax2m	106	3	colleagues	colleague	NNS
cord-311730-189vax2m	106	4	[	[	-LRB-
cord-311730-189vax2m	106	5	29	29	CD
cord-311730-189vax2m	106	6	]	]	-RRB-
cord-311730-189vax2m	106	7	determined	determine	VBD
cord-311730-189vax2m	106	8	the	the	DT
cord-311730-189vax2m	106	9	pharmacological	pharmacological	JJ
cord-311730-189vax2m	106	10	activity	activity	NN
cord-311730-189vax2m	106	11	of	of	IN
cord-311730-189vax2m	106	12	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	106	13	employing	employ	VBG
cord-311730-189vax2m	106	14	SARS	SARS	NNP
cord-311730-189vax2m	106	15	-	-	HYPH
cord-311730-189vax2m	106	16	CoV-2	CoV-2	NNP
cord-311730-189vax2m	106	17	infected	infected	JJ
cord-311730-189vax2m	106	18	Vero	Vero	NNP
cord-311730-189vax2m	106	19	cells	cell	NNS
cord-311730-189vax2m	106	20	.	.	.
cord-311730-189vax2m	107	1	Pharmacokinetic	pharmacokinetic	JJ
cord-311730-189vax2m	107	2	models	model	NNS
cord-311730-189vax2m	107	3	were	be	VBD
cord-311730-189vax2m	107	4	constructed	construct	VBN
cord-311730-189vax2m	107	5	by	by	IN
cord-311730-189vax2m	107	6	integrating	integrate	VBG
cord-311730-189vax2m	107	7	vitro	vitro	FW
cord-311730-189vax2m	107	8	data	datum	NNS
cord-311730-189vax2m	107	9	.	.	.
cord-311730-189vax2m	108	1	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-311730-189vax2m	108	2	concentrations	concentration	NNS
cord-311730-189vax2m	108	3	in	in	IN
cord-311730-189vax2m	108	4	lung	lung	NN
cord-311730-189vax2m	108	5	fluid	fluid	NN
cord-311730-189vax2m	108	6	were	be	VBD
cord-311730-189vax2m	108	7	simulated	simulate	VBN
cord-311730-189vax2m	108	8	.	.	.
cord-311730-189vax2m	109	1	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-311730-189vax2m	109	2	(	(	-LRB-
cord-311730-189vax2m	109	3	EC50	EC50	NNP
cord-311730-189vax2m	109	4	=	=	SYM
cord-311730-189vax2m	109	5	0.72	0.72	CD
cord-311730-189vax2m	109	6	μM	μM	NNP
cord-311730-189vax2m	109	7	)	)	-RRB-
cord-311730-189vax2m	109	8	was	be	VBD
cord-311730-189vax2m	109	9	found	find	VBN
cord-311730-189vax2m	109	10	to	to	TO
cord-311730-189vax2m	109	11	be	be	VB
cord-311730-189vax2m	109	12	more	more	RBR
cord-311730-189vax2m	109	13	potent	potent	JJ
cord-311730-189vax2m	109	14	than	than	IN
cord-311730-189vax2m	109	15	chloroquine	chloroquine	NN
cord-311730-189vax2m	109	16	(	(	-LRB-
cord-311730-189vax2m	109	17	EC50	EC50	NNP
cord-311730-189vax2m	109	18	=	=	SYM
cord-311730-189vax2m	109	19	5.47	5.47	CD
cord-311730-189vax2m	109	20	μM	μM	NNP
cord-311730-189vax2m	109	21	)	)	-RRB-
cord-311730-189vax2m	109	22	.	.	.
cord-311730-189vax2m	110	1	Based	base	VBN
cord-311730-189vax2m	110	2	on	on	IN
cord-311730-189vax2m	110	3	modeling	modeling	NN
cord-311730-189vax2m	110	4	,	,	,
cord-311730-189vax2m	110	5	a	a	DT
cord-311730-189vax2m	110	6	loading	loading	NN
cord-311730-189vax2m	110	7	dose	dose	NN
cord-311730-189vax2m	110	8	of	of	IN
cord-311730-189vax2m	110	9	400	400	CD
cord-311730-189vax2m	110	10	mg	mg	NNS
cord-311730-189vax2m	110	11	twice	twice	RB
cord-311730-189vax2m	110	12	daily	daily	RB
cord-311730-189vax2m	110	13	of	of	IN
cord-311730-189vax2m	110	14	hydroxychloroquine	hydroxychloroquine	NNP
cord-311730-189vax2m	110	15	sulfate	sulfate	NN
cord-311730-189vax2m	110	16	given	give	VBN
cord-311730-189vax2m	110	17	orally	orally	RB
cord-311730-189vax2m	110	18	,	,	,
cord-311730-189vax2m	110	19	followed	follow	VBN
cord-311730-189vax2m	110	20	by	by	IN
cord-311730-189vax2m	110	21	a	a	DT
cord-311730-189vax2m	110	22	maintenance	maintenance	NN
cord-311730-189vax2m	110	23	dose	dose	NN
cord-311730-189vax2m	110	24	of	of	IN
cord-311730-189vax2m	110	25	200	200	CD
cord-311730-189vax2m	110	26	mg	mg	NNS
cord-311730-189vax2m	110	27	given	give	VBN
cord-311730-189vax2m	110	28	twice	twice	RB
cord-311730-189vax2m	110	29	daily	daily	RB
cord-311730-189vax2m	110	30	for	for	IN
cord-311730-189vax2m	110	31	4	4	CD
cord-311730-189vax2m	110	32	days	day	NNS
cord-311730-189vax2m	110	33	may	may	MD
cord-311730-189vax2m	110	34	be	be	VB
cord-311730-189vax2m	110	35	recommended	recommend	VBN
cord-311730-189vax2m	110	36	for	for	IN
cord-311730-189vax2m	110	37	SARS	SARS	NNP
cord-311730-189vax2m	110	38	-	-	HYPH
cord-311730-189vax2m	110	39	CoV-2	CoV-2	NNP
cord-311730-189vax2m	110	40	infection	infection	NN
cord-311730-189vax2m	110	41	.	.	.
cord-311730-189vax2m	111	1	The	the	DT
cord-311730-189vax2m	111	2	in	in	IN
cord-311730-189vax2m	111	3	vitro	vitro	FW
cord-311730-189vax2m	111	4	cytotoxicity	cytotoxicity	NN
cord-311730-189vax2m	111	5	of	of	IN
cord-311730-189vax2m	111	6	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	111	7	was	be	VBD
cord-311730-189vax2m	111	8	determined	determine	VBN
cord-311730-189vax2m	111	9	in	in	IN
cord-311730-189vax2m	111	10	VeroE6	veroe6	NN
cord-311730-189vax2m	111	11	cells	cell	NNS
cord-311730-189vax2m	111	12	and	and	CC
cord-311730-189vax2m	111	13	showed	show	VBD
cord-311730-189vax2m	111	14	that	that	IN
cord-311730-189vax2m	111	15	the	the	DT
cord-311730-189vax2m	111	16	50	50	CD
cord-311730-189vax2m	111	17	%	%	NN
cord-311730-189vax2m	111	18	cytotoxic	cytotoxic	JJ
cord-311730-189vax2m	111	19	concentration	concentration	NN
cord-311730-189vax2m	111	20	(	(	-LRB-
cord-311730-189vax2m	111	21	CC	CC	NNP
cord-311730-189vax2m	111	22	50	50	CD
cord-311730-189vax2m	111	23	)	)	-RRB-
cord-311730-189vax2m	111	24	value	value	NN
cord-311730-189vax2m	111	25	for	for	IN
cord-311730-189vax2m	111	26	HCQ	HCQ	NNP
cord-311730-189vax2m	111	27	was	be	VBD
cord-311730-189vax2m	111	28	249.50	249.50	CD
cord-311730-189vax2m	111	29	μM	μM	.
cord-311730-189vax2m	111	30	[	[	-LRB-
cord-311730-189vax2m	111	31	30	30	CD
cord-311730-189vax2m	111	32	]	]	-RRB-
cord-311730-189vax2m	111	33	.	.	.
cord-311730-189vax2m	111	34	 	 	_SP
cord-311730-189vax2m	112	1	There	there	EX
cord-311730-189vax2m	112	2	are	be	VBP
cord-311730-189vax2m	112	3	patient	patient	JJ
cord-311730-189vax2m	112	4	demographics	demographic	NNS
cord-311730-189vax2m	112	5	and	and	CC
cord-311730-189vax2m	112	6	characteristics	characteristic	NNS
cord-311730-189vax2m	112	7	that	that	WDT
cord-311730-189vax2m	112	8	are	be	VBP
cord-311730-189vax2m	112	9	associated	associate	VBN
cord-311730-189vax2m	112	10	with	with	IN
cord-311730-189vax2m	112	11	a	a	DT
cord-311730-189vax2m	112	12	higher	high	JJR
cord-311730-189vax2m	112	13	likelihood	likelihood	NN
cord-311730-189vax2m	112	14	of	of	IN
cord-311730-189vax2m	112	15	developing	develop	VBG
cord-311730-189vax2m	112	16	drugrelated	drugrelated	JJ
cord-311730-189vax2m	112	17	QTc	QTc	NNP
cord-311730-189vax2m	112	18	prolongation	prolongation	NN
cord-311730-189vax2m	112	19	(	(	-LRB-
cord-311730-189vax2m	112	20	Table	table	NN
cord-311730-189vax2m	112	21	1	1	CD
cord-311730-189vax2m	112	22	)	)	-RRB-
cord-311730-189vax2m	112	23	.	.	.
cord-311730-189vax2m	113	1	All	all	DT
cord-311730-189vax2m	113	2	clinicians	clinician	NNS
cord-311730-189vax2m	113	3	and	and	CC
cord-311730-189vax2m	113	4	prescribing	prescribe	VBG
cord-311730-189vax2m	113	5	health	health	NN
cord-311730-189vax2m	113	6	providers	provider	NNS
cord-311730-189vax2m	113	7	should	should	MD
cord-311730-189vax2m	113	8	be	be	VB
cord-311730-189vax2m	113	9	familiar	familiar	JJ
cord-311730-189vax2m	113	10	with	with	IN
cord-311730-189vax2m	113	11	each	each	DT
cord-311730-189vax2m	113	12	.	.	.
cord-311730-189vax2m	114	1	The	the	DT
cord-311730-189vax2m	114	2	number	number	NN
cord-311730-189vax2m	114	3	of	of	IN
cord-311730-189vax2m	114	4	drugs	drug	NNS
cord-311730-189vax2m	114	5	that	that	WDT
cord-311730-189vax2m	114	6	can	can	MD
cord-311730-189vax2m	114	7	prolong	prolong	VB
cord-311730-189vax2m	114	8	the	the	DT
cord-311730-189vax2m	114	9	QTc	qtc	NN
cord-311730-189vax2m	114	10	is	be	VBZ
cord-311730-189vax2m	114	11	substantial	substantial	JJ
cord-311730-189vax2m	114	12	(	(	-LRB-
cord-311730-189vax2m	114	13	−	−	CD
cord-311730-189vax2m	114	14	220	220	CD
cord-311730-189vax2m	114	15	known	know	VBN
cord-311730-189vax2m	114	16	)	)	-RRB-
cord-311730-189vax2m	114	17	and	and	CC
cord-311730-189vax2m	114	18	typically	typically	RB
cord-311730-189vax2m	114	19	divided	divide	VBN
cord-311730-189vax2m	114	20	into	into	IN
cord-311730-189vax2m	114	21	those	those	DT
cord-311730-189vax2m	114	22	with	with	IN
cord-311730-189vax2m	114	23	a	a	DT
cord-311730-189vax2m	114	24	known	know	VBN
cord-311730-189vax2m	114	25	risk	risk	NN
cord-311730-189vax2m	114	26	of	of	IN
cord-311730-189vax2m	114	27	QTc	qtc	NN
cord-311730-189vax2m	114	28	prolongation	prolongation	NN
cord-311730-189vax2m	114	29	or	or	CC
cord-311730-189vax2m	114	30	torsades	torsades	FW
cord-311730-189vax2m	114	31	de	de	FW
cord-311730-189vax2m	114	32	pointes	pointes	FW
cord-311730-189vax2m	114	33	ventricular	ventricular	JJ
cord-311730-189vax2m	114	34	tachycardia	tachycardia	NN
cord-311730-189vax2m	114	35	,	,	,
cord-311730-189vax2m	114	36	possible	possible	JJ
cord-311730-189vax2m	114	37	risk	risk	NN
cord-311730-189vax2m	114	38	and	and	CC
cord-311730-189vax2m	114	39	conditional	conditional	JJ
cord-311730-189vax2m	114	40	risk	risk	NN
cord-311730-189vax2m	114	41	(	(	-LRB-
cord-311730-189vax2m	114	42	i.e.	i.e.	FW
cord-311730-189vax2m	114	43	if	if	IN
cord-311730-189vax2m	114	44	administered	administer	VBN
cord-311730-189vax2m	114	45	with	with	IN
cord-311730-189vax2m	114	46	another	another	DT
cord-311730-189vax2m	114	47	QTc	QTc	NNP
cord-311730-189vax2m	114	48	prolonging	prolong	VBG
cord-311730-189vax2m	114	49	drug	drug	NN
cord-311730-189vax2m	114	50	;	;	:
cord-311730-189vax2m	114	51	in	in	IN
cord-311730-189vax2m	114	52	the	the	DT
cord-311730-189vax2m	114	53	setting	setting	NN
cord-311730-189vax2m	114	54	of	of	IN
cord-311730-189vax2m	114	55	hypokalemia	hypokalemia	NN
cord-311730-189vax2m	114	56	or	or	CC
cord-311730-189vax2m	114	57	in	in	IN
cord-311730-189vax2m	114	58	patients	patient	NNS
cord-311730-189vax2m	114	59	with	with	IN
cord-311730-189vax2m	114	60	predisposing	predisposing	JJ
cord-311730-189vax2m	114	61	conditions	condition	NNS
cord-311730-189vax2m	114	62	such	such	JJ
cord-311730-189vax2m	114	63	as	as	IN
cord-311730-189vax2m	114	64	familial	familial	JJ
cord-311730-189vax2m	114	65	long	long	JJ
cord-311730-189vax2m	114	66	QT	qt	NN
cord-311730-189vax2m	114	67	syndrome	syndrome	NN
cord-311730-189vax2m	114	68	)	)	-RRB-
cord-311730-189vax2m	114	69	.	.	.
cord-311730-189vax2m	115	1	(	(	-LRB-
cord-311730-189vax2m	115	2	Crediblemeds.org	crediblemeds.org	NN
cord-311730-189vax2m	115	3	)	)	-RRB-
cord-311730-189vax2m	116	1	[	[	-LRB-
cord-311730-189vax2m	116	2	32	32	CD
cord-311730-189vax2m	116	3	]	]	-RRB-
cord-311730-189vax2m	117	1	In	in	IN
cord-311730-189vax2m	117	2	the	the	DT
cord-311730-189vax2m	117	3	context	context	NN
cord-311730-189vax2m	117	4	of	of	IN
cord-311730-189vax2m	117	5	current	current	JJ
cord-311730-189vax2m	117	6	treatment	treatment	NN
cord-311730-189vax2m	117	7	for	for	IN
cord-311730-189vax2m	117	8	COVID-19	COVID-19	NNP
cord-311730-189vax2m	117	9	,	,	,
cord-311730-189vax2m	117	10	including	include	VBG
cord-311730-189vax2m	117	11	empiric	empiric	JJ
cord-311730-189vax2m	117	12	regimens	regimen	NNS
cord-311730-189vax2m	117	13	being	be	VBG
cord-311730-189vax2m	117	14	employed	employ	VBN
cord-311730-189vax2m	117	15	by	by	IN
cord-311730-189vax2m	117	16	clinicians	clinician	NNS
cord-311730-189vax2m	117	17	as	as	IN
cord-311730-189vax2m	117	18	they	-PRON-	PRP
cord-311730-189vax2m	117	19	await	await	VBP
cord-311730-189vax2m	117	20	the	the	DT
cord-311730-189vax2m	117	21	results	result	NNS
cord-311730-189vax2m	117	22	of	of	IN
cord-311730-189vax2m	117	23	clinical	clinical	JJ
cord-311730-189vax2m	117	24	trials	trial	NNS
cord-311730-189vax2m	117	25	,	,	,
cord-311730-189vax2m	117	26	azithromycin	azithromycin	NNP
cord-311730-189vax2m	117	27	's	's	POS
cord-311730-189vax2m	117	28	effect	effect	NN
cord-311730-189vax2m	117	29	on	on	IN
cord-311730-189vax2m	117	30	QTc	QTc	NNS
cord-311730-189vax2m	117	31	must	must	MD
cord-311730-189vax2m	117	32	be	be	VB
cord-311730-189vax2m	117	33	recognized	recognize	VBN
cord-311730-189vax2m	117	34	and	and	CC
cord-311730-189vax2m	117	35	included	include	VBN
cord-311730-189vax2m	117	36	in	in	IN
cord-311730-189vax2m	117	37	the	the	DT
cord-311730-189vax2m	117	38	equation	equation	NN
cord-311730-189vax2m	117	39	.	.	.
cord-311730-189vax2m	118	1	The	the	DT
cord-311730-189vax2m	118	2	FDA	FDA	NNP
cord-311730-189vax2m	118	3	issued	issue	VBD
cord-311730-189vax2m	118	4	a	a	DT
cord-311730-189vax2m	118	5	warning	warning	NN
cord-311730-189vax2m	118	6	on	on	IN
cord-311730-189vax2m	118	7	May	May	NNP
cord-311730-189vax2m	118	8	17	17	CD
cord-311730-189vax2m	118	9	,	,	,
cord-311730-189vax2m	118	10	2012	2012	CD
cord-311730-189vax2m	118	11	on	on	IN
cord-311730-189vax2m	118	12	the	the	DT
cord-311730-189vax2m	118	13	risk	risk	NN
cord-311730-189vax2m	118	14	of	of	IN
cord-311730-189vax2m	118	15	potentially	potentially	RB
cord-311730-189vax2m	118	16	fatal	fatal	JJ
cord-311730-189vax2m	118	17	heart	heart	NN
cord-311730-189vax2m	118	18	rhythm	rhythm	NN
cord-311730-189vax2m	118	19	abnormalities	abnormality	NNS
cord-311730-189vax2m	118	20	associated	associate	VBN
cord-311730-189vax2m	118	21	with	with	IN
cord-311730-189vax2m	118	22	the	the	DT
cord-311730-189vax2m	118	23	drug	drug	NN
cord-311730-189vax2m	118	24	.	.	.
cord-311730-189vax2m	119	1	Employing	employ	VBG
cord-311730-189vax2m	119	2	a	a	DT
cord-311730-189vax2m	119	3	large	large	JJ
cord-311730-189vax2m	119	4	claims	claim	NNS
cord-311730-189vax2m	119	5	database	database	NN
cord-311730-189vax2m	119	6	of	of	IN
cord-311730-189vax2m	119	7	over	over	IN
cord-311730-189vax2m	119	8	12	12	CD
cord-311730-189vax2m	119	9	million	million	CD
cord-311730-189vax2m	119	10	patients	patient	NNS
cord-311730-189vax2m	119	11	with	with	IN
cord-311730-189vax2m	119	12	greater	great	JJR
cord-311730-189vax2m	119	13	than	than	IN
cord-311730-189vax2m	119	14	23	23	CD
cord-311730-189vax2m	119	15	million	million	CD
cord-311730-189vax2m	119	16	azithromycin	azithromycin	NNS
cord-311730-189vax2m	119	17	prescriptions	prescription	NNS
cord-311730-189vax2m	119	18	,	,	,
cord-311730-189vax2m	119	19	Patel	Patel	NNP
cord-311730-189vax2m	119	20	and	and	CC
cord-311730-189vax2m	119	21	colleagues	colleague	NNS
cord-311730-189vax2m	119	22	[	[	-LRB-
cord-311730-189vax2m	119	23	33	33	CD
cord-311730-189vax2m	119	24	]	]	-RRB-
cord-311730-189vax2m	119	25	identified	identify	VBD
cord-311730-189vax2m	119	26	nearly	nearly	RB
cord-311730-189vax2m	119	27	25	25	CD
cord-311730-189vax2m	119	28	%	%	NN
cord-311730-189vax2m	119	29	of	of	IN
cord-311730-189vax2m	119	30	patients	patient	NNS
cord-311730-189vax2m	119	31	were	be	VBD
cord-311730-189vax2m	119	32	receiving	receive	VBG
cord-311730-189vax2m	119	33	another	another	DT
cord-311730-189vax2m	119	34	drug	drug	NN
cord-311730-189vax2m	119	35	with	with	IN
cord-311730-189vax2m	119	36	QTc	QTc	NNS
cord-311730-189vax2m	119	37	producing	produce	VBG
cord-311730-189vax2m	119	38	effects	effect	NNS
cord-311730-189vax2m	119	39	.	.	.
cord-311730-189vax2m	120	1	The	the	DT
cord-311730-189vax2m	120	2	presence	presence	NN
cord-311730-189vax2m	120	3	of	of	IN
cord-311730-189vax2m	120	4	pre	pre	JJ
cord-311730-189vax2m	120	5	-	-	JJ
cord-311730-189vax2m	120	6	existing	existing	JJ
cord-311730-189vax2m	120	7	cardiac	cardiac	JJ
cord-311730-189vax2m	120	8	conditions	condition	NNS
cord-311730-189vax2m	120	9	was	be	VBD
cord-311730-189vax2m	120	10	~	~	CD
cord-311730-189vax2m	120	11	8.0	8.0	CD
cord-311730-189vax2m	120	12	%	%	NN
cord-311730-189vax2m	120	13	.	.	.
cord-311730-189vax2m	121	1	Neither	neither	CC
cord-311730-189vax2m	121	2	concomitant	concomitant	JJ
cord-311730-189vax2m	121	3	QTc	qtc	NN
cord-311730-189vax2m	121	4	prolonging	prolong	VBG
cord-311730-189vax2m	121	5	drugs	drug	NNS
cord-311730-189vax2m	121	6	nor	nor	CC
cord-311730-189vax2m	121	7	cardiac	cardiac	JJ
cord-311730-189vax2m	121	8	conditions	condition	NNS
cord-311730-189vax2m	121	9	differed	differ	VBD
cord-311730-189vax2m	121	10	after	after	IN
cord-311730-189vax2m	121	11	as	as	IN
cord-311730-189vax2m	121	12	compared	compare	VBN
cord-311730-189vax2m	121	13	with	with	IN
cord-311730-189vax2m	121	14	before	before	IN
cord-311730-189vax2m	121	15	the	the	DT
cord-311730-189vax2m	121	16	FDA	FDA	NNP
cord-311730-189vax2m	121	17	warning	warning	NN
cord-311730-189vax2m	121	18	.	.	.
cord-311730-189vax2m	122	1	The	the	DT
cord-311730-189vax2m	122	2	clinical	clinical	JJ
cord-311730-189vax2m	122	3	community	community	NN
cord-311730-189vax2m	122	4	to	to	TO
cord-311730-189vax2m	122	5	include	include	VB
cord-311730-189vax2m	122	6	emergency	emergency	NN
cord-311730-189vax2m	122	7	room	room	NN
cord-311730-189vax2m	122	8	physicians	physician	NNS
cord-311730-189vax2m	122	9	,	,	,
cord-311730-189vax2m	122	10	nurse	nurse	NN
cord-311730-189vax2m	122	11	practitioners	practitioner	NNS
cord-311730-189vax2m	122	12	,	,	,
cord-311730-189vax2m	122	13	physician	physician	NN
cord-311730-189vax2m	122	14	assistants	assistant	NNS
cord-311730-189vax2m	122	15	and	and	CC
cord-311730-189vax2m	122	16	pharmacists	pharmacist	NNS
cord-311730-189vax2m	122	17	,	,	,
cord-311730-189vax2m	122	18	as	as	RB
cord-311730-189vax2m	122	19	well	well	RB
cord-311730-189vax2m	122	20	as	as	IN
cord-311730-189vax2m	122	21	others	other	NNS
cord-311730-189vax2m	122	22	employing	employ	VBG
cord-311730-189vax2m	122	23	a	a	DT
cord-311730-189vax2m	122	24	tele	tele	NNP
cord-311730-189vax2m	122	25	-	-	HYPH
cord-311730-189vax2m	122	26	health	health	NNP
cord-311730-189vax2m	122	27	platform	platform	NN
cord-311730-189vax2m	122	28	must	must	MD
cord-311730-189vax2m	122	29	adopt	adopt	VB
cord-311730-189vax2m	122	30	a	a	DT
cord-311730-189vax2m	122	31	well	well	RB
cord-311730-189vax2m	122	32	-	-	HYPH
cord-311730-189vax2m	122	33	informed	inform	VBN
cord-311730-189vax2m	122	34	and	and	CC
cord-311730-189vax2m	122	35	consistent	consistent	JJ
cord-311730-189vax2m	122	36	approach	approach	NN
cord-311730-189vax2m	122	37	to	to	TO
cord-311730-189vax2m	122	38	safely	safely	RB
cord-311730-189vax2m	122	39	prescribe	prescribe	VB
cord-311730-189vax2m	122	40	drugs	drug	NNS
cord-311730-189vax2m	122	41	with	with	IN
cord-311730-189vax2m	122	42	QTc	QTc	NNS
cord-311730-189vax2m	122	43	prolonging	prolong	VBG
cord-311730-189vax2m	122	44	or	or	CC
cord-311730-189vax2m	122	45	proarrhythmic	proarrhythmic	JJ
cord-311730-189vax2m	122	46	potential	potential	NN
cord-311730-189vax2m	122	47	[	[	-LRB-
cord-311730-189vax2m	122	48	34	34	CD
cord-311730-189vax2m	122	49	]	]	-RRB-
cord-311730-189vax2m	122	50	.	.	.
cord-311730-189vax2m	123	1	A	a	DT
cord-311730-189vax2m	123	2	management	management	NN
cord-311730-189vax2m	123	3	algorithm	algorithm	NN
cord-311730-189vax2m	123	4	must	must	MD
cord-311730-189vax2m	123	5	include	include	VB
cord-311730-189vax2m	123	6	a	a	DT
cord-311730-189vax2m	123	7	comprehensive	comprehensive	JJ
cord-311730-189vax2m	123	8	understanding	understanding	NN
cord-311730-189vax2m	123	9	of	of	IN
cord-311730-189vax2m	123	10	drug	drug	NN
cord-311730-189vax2m	123	11	pharmacology	pharmacology	NN
cord-311730-189vax2m	123	12	,	,	,
cord-311730-189vax2m	123	13	risk	risk	NN
cord-311730-189vax2m	123	14	-	-	HYPH
cord-311730-189vax2m	123	15	benefit	benefit	NN
cord-311730-189vax2m	123	16	relationships	relationship	NNS
cord-311730-189vax2m	123	17	and	and	CC
cord-311730-189vax2m	123	18	a	a	DT
cord-311730-189vax2m	123	19	track	track	NN
cord-311730-189vax2m	123	20	record	record	NN
cord-311730-189vax2m	123	21	of	of	IN
cord-311730-189vax2m	123	22	safety	safety	NN
cord-311730-189vax2m	123	23	.	.	.
cord-311730-189vax2m	124	1	In	in	IN
cord-311730-189vax2m	124	2	addition	addition	NN
cord-311730-189vax2m	124	3	,	,	,
cord-311730-189vax2m	124	4	there	there	EX
cord-311730-189vax2m	124	5	must	must	MD
cord-311730-189vax2m	124	6	be	be	VB
cord-311730-189vax2m	124	7	a	a	DT
cord-311730-189vax2m	124	8	thorough	thorough	JJ
cord-311730-189vax2m	124	9	evaluation	evaluation	NN
cord-311730-189vax2m	124	10	of	of	IN
cord-311730-189vax2m	124	11	patient	patient	JJ
cord-311730-189vax2m	124	12	history	history	NN
cord-311730-189vax2m	124	13	focusing	focus	VBG
cord-311730-189vax2m	124	14	on	on	IN
cord-311730-189vax2m	124	15	conditions	condition	NNS
cord-311730-189vax2m	124	16	known	know	VBN
cord-311730-189vax2m	124	17	to	to	TO
cord-311730-189vax2m	124	18	be	be	VB
cord-311730-189vax2m	124	19	associated	associate	VBN
cord-311730-189vax2m	124	20	with	with	IN
cord-311730-189vax2m	124	21	arrhythmias	arrhythmia	NNS
cord-311730-189vax2m	124	22	,	,	,
cord-311730-189vax2m	124	23	as	as	RB
cord-311730-189vax2m	124	24	well	well	RB
cord-311730-189vax2m	124	25	as	as	IN
cord-311730-189vax2m	124	26	a	a	DT
cord-311730-189vax2m	124	27	detailed	detailed	JJ
cord-311730-189vax2m	124	28	family	family	NN
cord-311730-189vax2m	124	29	history	history	NN
cord-311730-189vax2m	124	30	of	of	IN
cord-311730-189vax2m	124	31	cardiomyopathy	cardiomyopathy	NN
cord-311730-189vax2m	124	32	,	,	,
cord-311730-189vax2m	124	33	arrhythmias	arrhythmias	RB
cord-311730-189vax2m	124	34	,	,	,
cord-311730-189vax2m	124	35	sudden	sudden	JJ
cord-311730-189vax2m	124	36	cardiac	cardiac	JJ
cord-311730-189vax2m	124	37	death	death	NN
cord-311730-189vax2m	124	38	and	and	CC
cord-311730-189vax2m	124	39	internal	internal	JJ
cord-311730-189vax2m	124	40	cardioverter	cardioverter	NN
cord-311730-189vax2m	124	41	-	-	HYPH
cord-311730-189vax2m	124	42	defibrillator	defibrillator	NN
cord-311730-189vax2m	124	43	(	(	-LRB-
cord-311730-189vax2m	124	44	ICD	ICD	NNP
cord-311730-189vax2m	124	45	)	)	-RRB-
cord-311730-189vax2m	124	46	insertion	insertion	NN
cord-311730-189vax2m	124	47	(	(	-LRB-
cord-311730-189vax2m	124	48	see	see	VB
cord-311730-189vax2m	124	49	Table	table	NN
cord-311730-189vax2m	124	50	1	1	CD
cord-311730-189vax2m	124	51	)	)	-RRB-
cord-311730-189vax2m	124	52	.	.	.
cord-311730-189vax2m	125	1	Last	last	JJ
cord-311730-189vax2m	125	2	,	,	,
cord-311730-189vax2m	125	3	dose	dose	NN
cord-311730-189vax2m	125	4	adjustments	adjustment	NNS
cord-311730-189vax2m	125	5	,	,	,
cord-311730-189vax2m	125	6	monitoring	monitoring	NN
cord-311730-189vax2m	125	7	of	of	IN
cord-311730-189vax2m	125	8	electrolytes	electrolyte	NNS
cord-311730-189vax2m	125	9	and	and	CC
cord-311730-189vax2m	125	10	serial	serial	JJ
cord-311730-189vax2m	125	11	electrocardiograms	electrocardiogram	NNS
cord-311730-189vax2m	125	12	should	should	MD
cord-311730-189vax2m	125	13	be	be	VB
cord-311730-189vax2m	125	14	included	include	VBN
cord-311730-189vax2m	125	15	in	in	IN
cord-311730-189vax2m	125	16	the	the	DT
cord-311730-189vax2m	125	17	management	management	NN
cord-311730-189vax2m	125	18	plan	plan	NN
cord-311730-189vax2m	125	19	when	when	WRB
cord-311730-189vax2m	125	20	indicated	indicate	VBN
cord-311730-189vax2m	125	21	.	.	.
cord-311730-189vax2m	126	1	Consensus	consensus	NN
cord-311730-189vax2m	126	2	recommendations	recommendation	NNS
cord-311730-189vax2m	126	3	from	from	IN
cord-311730-189vax2m	126	4	the	the	DT
cord-311730-189vax2m	126	5	Internal	Internal	NNP
cord-311730-189vax2m	126	6	Council	Council	NNP
cord-311730-189vax2m	126	7	for	for	IN
cord-311730-189vax2m	126	8	Harmonization	Harmonization	NNP
cord-311730-189vax2m	126	9	of	of	IN
cord-311730-189vax2m	126	10	Technical	Technical	NNP
cord-311730-189vax2m	126	11	Requirements	Requirements	NNPS
cord-311730-189vax2m	126	12	of	of	IN
cord-311730-189vax2m	126	13	Pharmaceuticals	Pharmaceuticals	NNPS
cord-311730-189vax2m	126	14	for	for	IN
cord-311730-189vax2m	126	15	Human	Human	NNP
cord-311730-189vax2m	126	16	Use	Use	NNP
cord-311730-189vax2m	126	17	(	(	-LRB-
cord-311730-189vax2m	126	18	ICH	ICH	NNP
cord-311730-189vax2m	126	19	)	)	-RRB-
cord-311730-189vax2m	126	20	should	should	MD
cord-311730-189vax2m	126	21	be	be	VB
cord-311730-189vax2m	126	22	followed	follow	VBN
cord-311730-189vax2m	126	23	(	(	-LRB-
cord-311730-189vax2m	126	24	www.ich.org	www.ich.org	NNP
cord-311730-189vax2m	126	25	)	)	-RRB-
cord-311730-189vax2m	126	26	.	.	.
cord-311730-189vax2m	127	1	Vandael	Vandael	NNP
cord-311730-189vax2m	127	2	et	et	FW
cord-311730-189vax2m	127	3	al	al	NNP
cord-311730-189vax2m	127	4	.	.	.
cord-311730-189vax2m	128	1	[	[	-LRB-
cord-311730-189vax2m	128	2	35	35	CD
cord-311730-189vax2m	128	3	]	]	-RRB-
cord-311730-189vax2m	128	4	developed	develop	VBD
cord-311730-189vax2m	128	5	a	a	DT
cord-311730-189vax2m	128	6	risk	risk	NN
cord-311730-189vax2m	128	7	score	score	NN
cord-311730-189vax2m	128	8	for	for	IN
cord-311730-189vax2m	128	9	QTc	qtc	NN
cord-311730-189vax2m	128	10	prolongation	prolongation	NN
cord-311730-189vax2m	128	11	following	follow	VBG
cord-311730-189vax2m	128	12	treatment	treatment	NN
cord-311730-189vax2m	128	13	with	with	IN
cord-311730-189vax2m	128	14	a	a	DT
cord-311730-189vax2m	128	15	drug	drug	NN
cord-311730-189vax2m	128	16	known	know	VBN
cord-311730-189vax2m	128	17	to	to	TO
cord-311730-189vax2m	128	18	have	have	VB
cord-311730-189vax2m	128	19	this	this	DT
cord-311730-189vax2m	128	20	potential	potential	JJ
cord-311730-189vax2m	128	21	effect	effect	NN
cord-311730-189vax2m	128	22	.	.	.
cord-311730-189vax2m	129	1	In	in	IN
cord-311730-189vax2m	129	2	a	a	DT
cord-311730-189vax2m	129	3	majority	majority	NN
cord-311730-189vax2m	129	4	of	of	IN
cord-311730-189vax2m	129	5	patients	patient	NNS
cord-311730-189vax2m	129	6	(	(	-LRB-
cord-311730-189vax2m	129	7	25	25	CD
cord-311730-189vax2m	129	8	of	of	IN
cord-311730-189vax2m	129	9	26	26	CD
cord-311730-189vax2m	129	10	)	)	-RRB-
cord-311730-189vax2m	129	11	,	,	,
cord-311730-189vax2m	129	12	the	the	DT
cord-311730-189vax2m	129	13	RISQ	RISQ	NNP
cord-311730-189vax2m	129	14	-	-	HYPH
cord-311730-189vax2m	129	15	PATH	path	NN
cord-311730-189vax2m	129	16	score	score	NN
cord-311730-189vax2m	129	17	was	be	VBD
cord-311730-189vax2m	129	18	≥	≥	CD
cord-311730-189vax2m	129	19	10	10	CD
cord-311730-189vax2m	130	1	(	(	-LRB-
cord-311730-189vax2m	130	2	Table	table	NN
cord-311730-189vax2m	130	3	2	2	CD
cord-311730-189vax2m	130	4	)	)	-RRB-
cord-311730-189vax2m	130	5	.	.	.
cord-311730-189vax2m	131	1	The	the	DT
cord-311730-189vax2m	131	2	score	score	NN
cord-311730-189vax2m	131	3	had	have	VBD
cord-311730-189vax2m	131	4	a	a	DT
cord-311730-189vax2m	131	5	sensitivity	sensitivity	NN
cord-311730-189vax2m	131	6	of	of	IN
cord-311730-189vax2m	131	7	92.6	92.6	CD
cord-311730-189vax2m	131	8	%	%	NN
cord-311730-189vax2m	131	9	(	(	-LRB-
cord-311730-189vax2m	131	10	95	95	CD
cord-311730-189vax2m	131	11	%	%	NN
cord-311730-189vax2m	131	12	CI	CI	NNP
cord-311730-189vax2m	131	13	78.4	78.4	CD
cord-311730-189vax2m	131	14	-	-	HYPH
cord-311730-189vax2m	131	15	99.8	99.8	CD
cord-311730-189vax2m	131	16	%	%	NN
cord-311730-189vax2m	131	17	)	)	-RRB-
cord-311730-189vax2m	131	18	and	and	CC
cord-311730-189vax2m	131	19	a	a	DT
cord-311730-189vax2m	131	20	negative	negative	JJ
cord-311730-189vax2m	131	21	predictive	predictive	JJ
cord-311730-189vax2m	131	22	value	value	NN
cord-311730-189vax2m	131	23	of	of	IN
cord-311730-189vax2m	131	24	98	98	CD
cord-311730-189vax2m	131	25	%	%	NN
cord-311730-189vax2m	131	26	(	(	-LRB-
cord-311730-189vax2m	131	27	95	95	CD
cord-311730-189vax2m	131	28	%	%	NN
cord-311730-189vax2m	131	29	CI	CI	NNP
cord-311730-189vax2m	131	30	88.2	88.2	CD
cord-311730-189vax2m	131	31	-	-	HYPH
cord-311730-189vax2m	131	32	99.9	99.9	CD
cord-311730-189vax2m	131	33	%	%	NN
cord-311730-189vax2m	131	34	)	)	-RRB-
cord-311730-189vax2m	131	35	.	.	.
cord-311730-189vax2m	132	1	The	the	DT
cord-311730-189vax2m	132	2	Brazilian	brazilian	JJ
cord-311730-189vax2m	132	3	study	study	NN
cord-311730-189vax2m	132	4	of	of	IN
cord-311730-189vax2m	132	5	chloroquine	chloroquine	NN
cord-311730-189vax2m	132	6	underscores	underscore	VBZ
cord-311730-189vax2m	132	7	the	the	DT
cord-311730-189vax2m	132	8	importance	importance	NN
cord-311730-189vax2m	132	9	of	of	IN
cord-311730-189vax2m	132	10	cardiovascular	cardiovascular	JJ
cord-311730-189vax2m	132	11	safety	safety	NN
cord-311730-189vax2m	132	12	when	when	WRB
cord-311730-189vax2m	132	13	using	use	VBG
cord-311730-189vax2m	132	14	or	or	CC
cord-311730-189vax2m	132	15	studying	study	VBG
cord-311730-189vax2m	132	16	antimalarial	antimalarial	JJ
cord-311730-189vax2m	132	17	drugs	drug	NNS
cord-311730-189vax2m	132	18	[	[	-LRB-
cord-311730-189vax2m	132	19	36	36	CD
cord-311730-189vax2m	132	20	]	]	-RRB-
cord-311730-189vax2m	132	21	.	.	.
cord-311730-189vax2m	133	1	The	the	DT
cord-311730-189vax2m	133	2	study	study	NN
cord-311730-189vax2m	133	3	included	include	VBD
cord-311730-189vax2m	133	4	81	81	CD
cord-311730-189vax2m	133	5	hospitalized	hospitalize	VBN
cord-311730-189vax2m	133	6	Covid-19	covid-19	NN
cord-311730-189vax2m	133	7	confirmed	confirm	VBD
cord-311730-189vax2m	133	8	patients	patient	NNS
cord-311730-189vax2m	133	9	of	of	IN
cord-311730-189vax2m	133	10	whom	whom	WP
cord-311730-189vax2m	133	11	approximately	approximately	RB
cord-311730-189vax2m	133	12	half	half	RB
cord-311730-189vax2m	133	13	received	receive	VBD
cord-311730-189vax2m	133	14	450	450	CD
cord-311730-189vax2m	133	15	mg	mg	NNP
cord-311730-189vax2m	133	16	chloroquine	chloroquine	NN
cord-311730-189vax2m	133	17	twice	twice	RB
cord-311730-189vax2m	133	18	daily	daily	RB
cord-311730-189vax2m	133	19	for	for	IN
cord-311730-189vax2m	133	20	five	five	CD
cord-311730-189vax2m	133	21	days	day	NNS
cord-311730-189vax2m	133	22	and	and	CC
cord-311730-189vax2m	133	23	the	the	DT
cord-311730-189vax2m	133	24	remainder	remainder	NN
cord-311730-189vax2m	133	25	received	receive	VBD
cord-311730-189vax2m	133	26	600	600	CD
cord-311730-189vax2m	133	27	mg	mg	NNS
cord-311730-189vax2m	133	28	twice	twice	RB
cord-311730-189vax2m	133	29	daily	daily	RB
cord-311730-189vax2m	133	30	for	for	IN
cord-311730-189vax2m	133	31	10	10	CD
cord-311730-189vax2m	133	32	days	day	NNS
cord-311730-189vax2m	133	33	.	.	.
cord-311730-189vax2m	134	1	The	the	DT
cord-311730-189vax2m	134	2	CloroCovid-19	CloroCovid-19	NNP
cord-311730-189vax2m	134	3	study	study	NN
cord-311730-189vax2m	134	4	was	be	VBD
cord-311730-189vax2m	134	5	performed	perform	VBN
cord-311730-189vax2m	134	6	on	on	IN
cord-311730-189vax2m	134	7	a	a	DT
cord-311730-189vax2m	134	8	background	background	NN
cord-311730-189vax2m	134	9	of	of	IN
cord-311730-189vax2m	134	10	treatment	treatment	NN
cord-311730-189vax2m	134	11	with	with	IN
cord-311730-189vax2m	134	12	azithromycin	azithromycin	NN
cord-311730-189vax2m	134	13	and	and	CC
cord-311730-189vax2m	134	14	ceftriaxone	ceftriaxone	NN
cord-311730-189vax2m	134	15	.	.	.
cord-311730-189vax2m	135	1	Arrhythmias	arrhythmia	NNS
cord-311730-189vax2m	135	2	were	be	VBD
cord-311730-189vax2m	135	3	observed	observe	VBN
cord-311730-189vax2m	135	4	within	within	IN
cord-311730-189vax2m	135	5	three	three	CD
cord-311730-189vax2m	135	6	days	day	NNS
cord-311730-189vax2m	135	7	of	of	IN
cord-311730-189vax2m	135	8	study	study	NN
cord-311730-189vax2m	135	9	initiation	initiation	NN
cord-311730-189vax2m	135	10	and	and	CC
cord-311730-189vax2m	135	11	by	by	IN
cord-311730-189vax2m	135	12	six	six	CD
cord-311730-189vax2m	135	13	days	day	NNS
cord-311730-189vax2m	135	14	11	11	CD
cord-311730-189vax2m	135	15	patients	patient	NNS
cord-311730-189vax2m	135	16	had	have	VBD
cord-311730-189vax2m	135	17	died	die	VBN
cord-311730-189vax2m	135	18	.	.	.
cord-311730-189vax2m	136	1	There	there	EX
cord-311730-189vax2m	136	2	was	be	VBD
cord-311730-189vax2m	136	3	a	a	DT
cord-311730-189vax2m	136	4	greater	great	JJR
cord-311730-189vax2m	136	5	likelihood	likelihood	NN
cord-311730-189vax2m	136	6	of	of	IN
cord-311730-189vax2m	136	7	having	have	VBG
cord-311730-189vax2m	136	8	a	a	DT
cord-311730-189vax2m	136	9	QTc	qtc	NN
cord-311730-189vax2m	136	10	interval	interval	NN
cord-311730-189vax2m	136	11	>	>	XX
cord-311730-189vax2m	137	1	500	500	CD
cord-311730-189vax2m	137	2	ms	m	NNS
cord-311730-189vax2m	137	3	(	(	-LRB-
cord-311730-189vax2m	137	4	25	25	CD
cord-311730-189vax2m	137	5	%	%	NN
cord-311730-189vax2m	137	6	)	)	-RRB-
cord-311730-189vax2m	137	7	in	in	IN
cord-311730-189vax2m	137	8	patients	patient	NNS
cord-311730-189vax2m	137	9	receiving	receive	VBG
cord-311730-189vax2m	137	10	high	high	JJ
cord-311730-189vax2m	137	11	-	-	HYPH
cord-311730-189vax2m	137	12	dose	dose	NN
cord-311730-189vax2m	137	13	chloroquine	chloroquine	NN
cord-311730-189vax2m	137	14	.	.	.
cord-311730-189vax2m	138	1	Accordingly	accordingly	RB
cord-311730-189vax2m	138	2	,	,	,
cord-311730-189vax2m	138	3	this	this	DT
cord-311730-189vax2m	138	4	arm	arm	NN
cord-311730-189vax2m	138	5	of	of	IN
cord-311730-189vax2m	138	6	the	the	DT
cord-311730-189vax2m	138	7	study	study	NN
cord-311730-189vax2m	138	8	was	be	VBD
cord-311730-189vax2m	138	9	terminated	terminate	VBN
cord-311730-189vax2m	138	10	.	.	.
cord-311730-189vax2m	139	1	While	while	IN
cord-311730-189vax2m	139	2	more	more	RBR
cord-311730-189vax2m	139	3	detailed	detailed	JJ
cord-311730-189vax2m	139	4	information	information	NN
cord-311730-189vax2m	139	5	is	be	VBZ
cord-311730-189vax2m	139	6	needed	need	VBN
cord-311730-189vax2m	139	7	,	,	,
cord-311730-189vax2m	139	8	high	high	JJ
cord-311730-189vax2m	139	9	-	-	HYPH
cord-311730-189vax2m	139	10	dose	dose	NN
cord-311730-189vax2m	139	11	chloroquine	chloroquine	NN
cord-311730-189vax2m	139	12	may	may	MD
cord-311730-189vax2m	139	13	not	not	RB
cord-311730-189vax2m	139	14	be	be	VB
cord-311730-189vax2m	139	15	safe	safe	JJ
cord-311730-189vax2m	139	16	in	in	IN
cord-311730-189vax2m	139	17	the	the	DT
cord-311730-189vax2m	139	18	treatment	treatment	NN
cord-311730-189vax2m	139	19	of	of	IN
cord-311730-189vax2m	139	20	Covid-19	covid-19	NN
cord-311730-189vax2m	139	21	.	.	.
cord-311730-189vax2m	140	1	The	the	DT
cord-311730-189vax2m	140	2	safety	safety	NN
cord-311730-189vax2m	140	3	of	of	IN
cord-311730-189vax2m	140	4	lower	low	JJR
cord-311730-189vax2m	140	5	doses	dose	NNS
cord-311730-189vax2m	140	6	must	must	MD
cord-311730-189vax2m	140	7	be	be	VB
cord-311730-189vax2m	140	8	established	establish	VBN
cord-311730-189vax2m	140	9	in	in	IN
cord-311730-189vax2m	140	10	Covid-19	covid-19	NN
cord-311730-189vax2m	140	11	.	.	.
cord-311730-189vax2m	141	1	It	-PRON-	PRP
cord-311730-189vax2m	141	2	is	be	VBZ
cord-311730-189vax2m	141	3	vital	vital	JJ
cord-311730-189vax2m	141	4	to	to	TO
cord-311730-189vax2m	141	5	educate	educate	VB
cord-311730-189vax2m	141	6	the	the	DT
cord-311730-189vax2m	141	7	lay	lay	NN
cord-311730-189vax2m	141	8	community	community	NN
cord-311730-189vax2m	141	9	about	about	IN
cord-311730-189vax2m	141	10	the	the	DT
cord-311730-189vax2m	141	11	potential	potential	JJ
cord-311730-189vax2m	141	12	risks	risk	NNS
cord-311730-189vax2m	141	13	associated	associate	VBN
cord-311730-189vax2m	141	14	with	with	IN
cord-311730-189vax2m	141	15	non	non	JJ
cord-311730-189vax2m	141	16	-	-	JJ
cord-311730-189vax2m	141	17	medicinal	medicinal	JJ
cord-311730-189vax2m	141	18	chloroquine	chloroquine	NN
cord-311730-189vax2m	141	19	products	product	NNS
cord-311730-189vax2m	141	20	.	.	.
cord-311730-189vax2m	142	1	Similarly	similarly	RB
cord-311730-189vax2m	142	2	,	,	,
cord-311730-189vax2m	142	3	patients	patient	NNS
cord-311730-189vax2m	142	4	with	with	IN
cord-311730-189vax2m	142	5	Covid-19	covid-19	NN
cord-311730-189vax2m	142	6	for	for	IN
cord-311730-189vax2m	142	7	whom	whom	WP
cord-311730-189vax2m	142	8	a	a	DT
cord-311730-189vax2m	142	9	clinician	clinician	NN
cord-311730-189vax2m	142	10	believes	believe	VBZ
cord-311730-189vax2m	142	11	that	that	IN
cord-311730-189vax2m	142	12	either	either	CC
cord-311730-189vax2m	142	13	chloroquine	chloroquine	NN
cord-311730-189vax2m	142	14	or	or	CC
cord-311730-189vax2m	142	15	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	142	16	is	be	VBZ
cord-311730-189vax2m	142	17	indicated	indicate	VBN
cord-311730-189vax2m	142	18	must	must	MD
cord-311730-189vax2m	142	19	receive	receive	VB
cord-311730-189vax2m	142	20	information	information	NN
cord-311730-189vax2m	142	21	,	,	,
cord-311730-189vax2m	142	22	preferably	preferably	RB
cord-311730-189vax2m	142	23	in	in	IN
cord-311730-189vax2m	142	24	the	the	DT
cord-311730-189vax2m	142	25	form	form	NN
cord-311730-189vax2m	142	26	of	of	IN
cord-311730-189vax2m	142	27	a	a	DT
cord-311730-189vax2m	142	28	fact	fact	NN
cord-311730-189vax2m	142	29	sheet	sheet	NN
cord-311730-189vax2m	142	30	that	that	WDT
cord-311730-189vax2m	142	31	clearly	clearly	RB
cord-311730-189vax2m	142	32	summarized	summarize	VBD
cord-311730-189vax2m	142	33	the	the	DT
cord-311730-189vax2m	142	34	dose	dose	NN
cord-311730-189vax2m	142	35	,	,	,
cord-311730-189vax2m	142	36	duration	duration	NN
cord-311730-189vax2m	142	37	of	of	IN
cord-311730-189vax2m	142	38	treatment	treatment	NN
cord-311730-189vax2m	142	39	,	,	,
cord-311730-189vax2m	142	40	potential	potential	JJ
cord-311730-189vax2m	142	41	risks	risk	NNS
cord-311730-189vax2m	142	42	,	,	,
cord-311730-189vax2m	142	43	side	side	NN
cord-311730-189vax2m	142	44	-	-	HYPH
cord-311730-189vax2m	142	45	effects	effect	NNS
cord-311730-189vax2m	142	46	and	and	CC
cord-311730-189vax2m	142	47	drug	drug	NN
cord-311730-189vax2m	142	48	-	-	HYPH
cord-311730-189vax2m	142	49	drug	drug	NN
cord-311730-189vax2m	142	50	interactions	interaction	NNS
cord-311730-189vax2m	142	51	.	.	.
cord-311730-189vax2m	142	52	 	 	_SP
cord-311730-189vax2m	143	1	The	the	DT
cord-311730-189vax2m	143	2	number	number	NN
cord-311730-189vax2m	143	3	of	of	IN
cord-311730-189vax2m	143	4	clinical	clinical	JJ
cord-311730-189vax2m	143	5	trials	trial	NNS
cord-311730-189vax2m	143	6	in	in	IN
cord-311730-189vax2m	143	7	Covid-19	covid-19	NN
cord-311730-189vax2m	143	8	patients	patient	NNS
cord-311730-189vax2m	143	9	,	,	,
cord-311730-189vax2m	143	10	either	either	CC
cord-311730-189vax2m	143	11	planned	plan	VBN
cord-311730-189vax2m	143	12	or	or	CC
cord-311730-189vax2m	143	13	ongoing	ongoing	JJ
cord-311730-189vax2m	143	14	is	be	VBZ
cord-311730-189vax2m	143	15	increasing	increase	VBG
cord-311730-189vax2m	143	16	on	on	IN
cord-311730-189vax2m	143	17	a	a	DT
cord-311730-189vax2m	143	18	daily	daily	JJ
cord-311730-189vax2m	143	19	basis	basis	NN
cord-311730-189vax2m	143	20	.	.	.
cord-311730-189vax2m	144	1	The	the	DT
cord-311730-189vax2m	144	2	reader	reader	NN
cord-311730-189vax2m	144	3	is	be	VBZ
cord-311730-189vax2m	144	4	referred	refer	VBN
cord-311730-189vax2m	144	5	to	to	IN
cord-311730-189vax2m	144	6	clinicaltrial.gov	clinicaltrial.gov	NNP
cord-311730-189vax2m	144	7	for	for	IN
cord-311730-189vax2m	144	8	regular	regular	JJ
cord-311730-189vax2m	144	9	updates	update	NNS
cord-311730-189vax2m	144	10	.	.	.
cord-311730-189vax2m	145	1	The	the	DT
cord-311730-189vax2m	145	2	World	World	NNP
cord-311730-189vax2m	145	3	Health	Health	NNP
cord-311730-189vax2m	145	4	Organization	Organization	NNP
cord-311730-189vax2m	145	5	(	(	-LRB-
cord-311730-189vax2m	145	6	WHO	who	WP
cord-311730-189vax2m	145	7	)	)	-RRB-
cord-311730-189vax2m	145	8	working	work	VBG
cord-311730-189vax2m	145	9	with	with	IN
cord-311730-189vax2m	145	10	the	the	DT
cord-311730-189vax2m	145	11	Global	Global	NNP
cord-311730-189vax2m	145	12	Research	Research	NNP
cord-311730-189vax2m	145	13	Collaborative	Collaborative	NNP
cord-311730-189vax2m	145	14	for	for	IN
cord-311730-189vax2m	145	15	Infectious	Infectious	NNP
cord-311730-189vax2m	145	16	Disease	Disease	NNP
cord-311730-189vax2m	145	17	Preparedness	Preparedness	NNP
cord-311730-189vax2m	145	18	(	(	-LRB-
cord-311730-189vax2m	145	19	GLOPID	GLOPID	NNP
cord-311730-189vax2m	145	20	-	-	HYPH
cord-311730-189vax2m	145	21	R	R	NNP
cord-311730-189vax2m	145	22	)	)	-RRB-
cord-311730-189vax2m	145	23	established	establish	VBD
cord-311730-189vax2m	145	24	a	a	DT
cord-311730-189vax2m	145	25	Covid-19	covid-19	NN
cord-311730-189vax2m	145	26	research	research	NN
cord-311730-189vax2m	145	27	roadmap	roadmap	NN
cord-311730-189vax2m	145	28	(	(	-LRB-
cord-311730-189vax2m	145	29	www.glopi	www.glopi	NNP
cord-311730-189vax2m	145	30	d-r.org	d-r.org	NN
cord-311730-189vax2m	145	31	)	)	-RRB-
cord-311730-189vax2m	145	32	in	in	IN
cord-311730-189vax2m	145	33	January	January	NNP
cord-311730-189vax2m	145	34	2020	2020	CD
cord-311730-189vax2m	145	35	.	.	.
cord-311730-189vax2m	146	1	The	the	DT
cord-311730-189vax2m	146	2	design	design	NN
cord-311730-189vax2m	146	3	is	be	VBZ
cord-311730-189vax2m	146	4	tailored	tailor	VBN
cord-311730-189vax2m	146	5	for	for	IN
cord-311730-189vax2m	146	6	a	a	DT
cord-311730-189vax2m	146	7	global	global	JJ
cord-311730-189vax2m	146	8	research	research	NN
cord-311730-189vax2m	146	9	response	response	NN
cord-311730-189vax2m	146	10	that	that	WDT
cord-311730-189vax2m	146	11	embraces	embrace	VBZ
cord-311730-189vax2m	146	12	cross	cross	JJ
cord-311730-189vax2m	146	13	-	-	JJ
cord-311730-189vax2m	146	14	border	border	JJ
cord-311730-189vax2m	146	15	collaborations	collaboration	NNS
cord-311730-189vax2m	146	16	and	and	CC
cord-311730-189vax2m	146	17	partnerships	partnership	NNS
cord-311730-189vax2m	146	18	across	across	IN
cord-311730-189vax2m	146	19	professional	professional	JJ
cord-311730-189vax2m	146	20	disciplines	discipline	NNS
cord-311730-189vax2m	146	21	worldwide	worldwide	RB
cord-311730-189vax2m	146	22	.	.	.
cord-311730-189vax2m	147	1	A	a	DT
cord-311730-189vax2m	147	2	major	major	JJ
cord-311730-189vax2m	147	3	focus	focus	NN
cord-311730-189vax2m	147	4	of	of	IN
cord-311730-189vax2m	147	5	GLOPID	GLOPID	NNP
cord-311730-189vax2m	147	6	-	-	HYPH
cord-311730-189vax2m	147	7	R	R	NNP
cord-311730-189vax2m	147	8	is	be	VBZ
cord-311730-189vax2m	147	9	data	datum	NNS
cord-311730-189vax2m	147	10	sharing	sharing	NN
cord-311730-189vax2m	147	11	based	base	VBN
cord-311730-189vax2m	147	12	on	on	IN
cord-311730-189vax2m	147	13	filling	fill	VBG
cord-311730-189vax2m	147	14	knowledge	knowledge	NN
cord-311730-189vax2m	147	15	gaps	gap	NNS
cord-311730-189vax2m	147	16	,	,	,
cord-311730-189vax2m	147	17	establishing	establish	VBG
cord-311730-189vax2m	147	18	research	research	NN
cord-311730-189vax2m	147	19	priorities	priority	NNS
cord-311730-189vax2m	147	20	and	and	CC
cord-311730-189vax2m	147	21	accelerating	accelerate	VBG
cord-311730-189vax2m	147	22	the	the	DT
cord-311730-189vax2m	147	23	generation	generation	NN
cord-311730-189vax2m	147	24	of	of	IN
cord-311730-189vax2m	147	25	scientific	scientific	JJ
cord-311730-189vax2m	147	26	information	information	NN
cord-311730-189vax2m	147	27	required	require	VBN
cord-311730-189vax2m	147	28	to	to	TO
cord-311730-189vax2m	147	29	address	address	VB
cord-311730-189vax2m	147	30	the	the	DT
cord-311730-189vax2m	147	31	Covid-19	covid-19	NN
cord-311730-189vax2m	147	32	pandemic	pandemic	NN
cord-311730-189vax2m	147	33	.	.	.
cord-311730-189vax2m	148	1	An	an	DT
cord-311730-189vax2m	148	2	initial	initial	JJ
cord-311730-189vax2m	148	3	evaluation	evaluation	NN
cord-311730-189vax2m	148	4	by	by	IN
cord-311730-189vax2m	148	5	the	the	DT
cord-311730-189vax2m	148	6	WHO	WHO	NNP
cord-311730-189vax2m	148	7	called	call	VBD
cord-311730-189vax2m	148	8	for	for	IN
cord-311730-189vax2m	148	9	priority	priority	NN
cord-311730-189vax2m	148	10	to	to	TO
cord-311730-189vax2m	148	11	embark	embark	VB
cord-311730-189vax2m	148	12	upon	upon	IN
cord-311730-189vax2m	148	13	global	global	JJ
cord-311730-189vax2m	148	14	research	research	NN
cord-311730-189vax2m	148	15	built	build	VBN
cord-311730-189vax2m	148	16	on	on	IN
cord-311730-189vax2m	148	17	common	common	JJ
cord-311730-189vax2m	148	18	platforms	platform	NNS
cord-311730-189vax2m	148	19	for	for	IN
cord-311730-189vax2m	148	20	standardized	standardized	JJ
cord-311730-189vax2m	148	21	processes	process	NNS
cord-311730-189vax2m	148	22	,	,	,
cord-311730-189vax2m	148	23	protocols	protocol	NNS
cord-311730-189vax2m	148	24	and	and	CC
cord-311730-189vax2m	148	25	tools	tool	NNS
cord-311730-189vax2m	148	26	.	.	.
cord-311730-189vax2m	149	1	It	-PRON-	PRP
cord-311730-189vax2m	149	2	also	also	RB
cord-311730-189vax2m	149	3	emphasized	emphasize	VBD
cord-311730-189vax2m	149	4	several	several	JJ
cord-311730-189vax2m	149	5	knowledge	knowledge	NN
cord-311730-189vax2m	149	6	gaps	gap	NNS
cord-311730-189vax2m	149	7	about	about	IN
cord-311730-189vax2m	149	8	SARS	SARS	NNP
cord-311730-189vax2m	149	9	-	-	HYPH
cord-311730-189vax2m	149	10	CoV-2	CoV-2	NNP
cord-311730-189vax2m	149	11	to	to	TO
cord-311730-189vax2m	149	12	include	include	VB
cord-311730-189vax2m	149	13	compartments	compartment	NNS
cord-311730-189vax2m	149	14	of	of	IN
cord-311730-189vax2m	149	15	replication	replication	NN
cord-311730-189vax2m	149	16	,	,	,
cord-311730-189vax2m	149	17	the	the	DT
cord-311730-189vax2m	149	18	prognostic	prognostic	JJ
cord-311730-189vax2m	149	19	importance	importance	NN
cord-311730-189vax2m	149	20	of	of	IN
cord-311730-189vax2m	149	21	viral	viral	JJ
cord-311730-189vax2m	149	22	load	load	NN
cord-311730-189vax2m	149	23	,	,	,
cord-311730-189vax2m	149	24	immune	immune	NN
cord-311730-189vax2m	149	25	-	-	HYPH
cord-311730-189vax2m	149	26	biomarkers	biomarker	NNS
cord-311730-189vax2m	149	27	,	,	,
cord-311730-189vax2m	149	28	genotype	genotype	NN
cord-311730-189vax2m	149	29	-	-	HYPH
cord-311730-189vax2m	149	30	phenotype	phenotype	NN
cord-311730-189vax2m	149	31	relationships	relationship	NNS
cord-311730-189vax2m	149	32	,	,	,
cord-311730-189vax2m	149	33	genotype	genotype	NN
cord-311730-189vax2m	149	34	drifts	drift	NNS
cord-311730-189vax2m	149	35	that	that	WDT
cord-311730-189vax2m	149	36	might	may	MD
cord-311730-189vax2m	149	37	impact	impact	VB
cord-311730-189vax2m	149	38	diagnostic	diagnostic	JJ
cord-311730-189vax2m	149	39	assays	assay	NNS
cord-311730-189vax2m	149	40	and	and	CC
cord-311730-189vax2m	149	41	technical	technical	JJ
cord-311730-189vax2m	149	42	limitations	limitation	NNS
cord-311730-189vax2m	149	43	for	for	IN
cord-311730-189vax2m	149	44	serologic	serologic	NNP
cord-311730-189vax2m	149	45	assay	assay	NN
cord-311730-189vax2m	149	46	development	development	NN
cord-311730-189vax2m	149	47	(	(	-LRB-
cord-311730-189vax2m	150	1	simple	simple	JJ
cord-311730-189vax2m	150	2	immunofluorescence	immunofluorescence	NN
cord-311730-189vax2m	150	3	assay	assay	NN
cord-311730-189vax2m	150	4	[	[	-LRB-
cord-311730-189vax2m	150	5	IFA	IFA	NNP
cord-311730-189vax2m	150	6	]	]	-RRB-
cord-311730-189vax2m	150	7	,	,	,
cord-311730-189vax2m	150	8	differential	differential	JJ
cord-311730-189vax2m	150	9	IFA	IFA	NNP
cord-311730-189vax2m	150	10	,	,	,
cord-311730-189vax2m	150	11	enzyme	enzyme	NN
cord-311730-189vax2m	150	12	linked	link	VBN
cord-311730-189vax2m	150	13	immunoabsorbance	immunoabsorbance	NN
cord-311730-189vax2m	150	14	assay	assay	NN
cord-311730-189vax2m	150	15	[	[	-LRB-
cord-311730-189vax2m	150	16	ELISA	ELISA	NNP
cord-311730-189vax2m	150	17	]	]	-RRB-
cord-311730-189vax2m	150	18	and	and	CC
cord-311730-189vax2m	150	19	neutralization	neutralization	NN
cord-311730-189vax2m	150	20	assays	assay	NNS
cord-311730-189vax2m	150	21	)	)	-RRB-
cord-311730-189vax2m	150	22	.	.	.
cord-311730-189vax2m	151	1	The	the	DT
cord-311730-189vax2m	151	2	group	group	NN
cord-311730-189vax2m	151	3	exhibited	exhibit	VBD
cord-311730-189vax2m	151	4	substantial	substantial	JJ
cord-311730-189vax2m	151	5	foresight	foresight	NN
cord-311730-189vax2m	151	6	and	and	CC
cord-311730-189vax2m	151	7	raised	raise	VBD
cord-311730-189vax2m	151	8	questions	question	NNS
cord-311730-189vax2m	151	9	about	about	IN
cord-311730-189vax2m	151	10	the	the	DT
cord-311730-189vax2m	151	11	development	development	NN
cord-311730-189vax2m	151	12	of	of	IN
cord-311730-189vax2m	151	13	point	point	NN
cord-311730-189vax2m	151	14	-	-	HYPH
cord-311730-189vax2m	151	15	of	of	IN
cord-311730-189vax2m	151	16	-	-	HYPH
cord-311730-189vax2m	151	17	care	care	NN
cord-311730-189vax2m	151	18	testing	testing	NN
cord-311730-189vax2m	151	19	,	,	,
cord-311730-189vax2m	151	20	the	the	DT
cord-311730-189vax2m	151	21	identification	identification	NN
cord-311730-189vax2m	151	22	of	of	IN
cord-311730-189vax2m	151	23	prognostic	prognostic	JJ
cord-311730-189vax2m	151	24	markers	marker	NNS
cord-311730-189vax2m	151	25	and	and	CC
cord-311730-189vax2m	151	26	digital	digital	JJ
cord-311730-189vax2m	151	27	solutions	solution	NNS
cord-311730-189vax2m	151	28	for	for	IN
cord-311730-189vax2m	151	29	field	field	NN
cord-311730-189vax2m	151	30	laboratory	laboratory	NN
cord-311730-189vax2m	151	31	needs	need	NNS
cord-311730-189vax2m	151	32	.	.	.
cord-311730-189vax2m	152	1	They	-PRON-	PRP
cord-311730-189vax2m	152	2	also	also	RB
cord-311730-189vax2m	152	3	emphasized	emphasize	VBD
cord-311730-189vax2m	152	4	the	the	DT
cord-311730-189vax2m	152	5	importance	importance	NN
cord-311730-189vax2m	152	6	of	of	IN
cord-311730-189vax2m	152	7	ethical	ethical	JJ
cord-311730-189vax2m	152	8	considerations	consideration	NNS
cord-311730-189vax2m	152	9	as	as	IN
cord-311730-189vax2m	152	10	being	be	VBG
cord-311730-189vax2m	152	11	crucial	crucial	JJ
cord-311730-189vax2m	152	12	to	to	IN
cord-311730-189vax2m	152	13	governance	governance	NN
cord-311730-189vax2m	152	14	,	,	,
cord-311730-189vax2m	152	15	transparency	transparency	NN
cord-311730-189vax2m	152	16	,	,	,
cord-311730-189vax2m	152	17	accountability	accountability	NN
cord-311730-189vax2m	152	18	,	,	,
cord-311730-189vax2m	152	19	equity	equity	NN
cord-311730-189vax2m	152	20	and	and	CC
cord-311730-189vax2m	152	21	trust	trust	NN
cord-311730-189vax2m	152	22	.	.	.
cord-311730-189vax2m	153	1	Last	last	RB
cord-311730-189vax2m	153	2	,	,	,
cord-311730-189vax2m	153	3	the	the	DT
cord-311730-189vax2m	153	4	group	group	NN
cord-311730-189vax2m	153	5	underscored	underscore	VBD
cord-311730-189vax2m	153	6	the	the	DT
cord-311730-189vax2m	153	7	importance	importance	NN
cord-311730-189vax2m	153	8	of	of	IN
cord-311730-189vax2m	153	9	establishing	establish	VBG
cord-311730-189vax2m	153	10	a	a	DT
cord-311730-189vax2m	153	11	framework	framework	NN
cord-311730-189vax2m	153	12	for	for	IN
cord-311730-189vax2m	153	13	social	social	JJ
cord-311730-189vax2m	153	14	science	science	NN
cord-311730-189vax2m	153	15	research	research	NN
cord-311730-189vax2m	153	16	,	,	,
cord-311730-189vax2m	153	17	global	global	JJ
cord-311730-189vax2m	153	18	social	social	JJ
cord-311730-189vax2m	153	19	science	science	NN
cord-311730-189vax2m	153	20	researchers	researcher	NNS
cord-311730-189vax2m	153	21	and	and	CC
cord-311730-189vax2m	153	22	understanding	understand	VBG
cord-311730-189vax2m	153	23	social	social	JJ
cord-311730-189vax2m	153	24	and	and	CC
cord-311730-189vax2m	153	25	behavioral	behavioral	JJ
cord-311730-189vax2m	153	26	dynamics	dynamic	NNS
cord-311730-189vax2m	153	27	during	during	IN
cord-311730-189vax2m	153	28	the	the	DT
cord-311730-189vax2m	153	29	Covid-19	covid-19	NN
cord-311730-189vax2m	153	30	pandemic	pandemic	NN
cord-311730-189vax2m	153	31	(	(	-LRB-
cord-311730-189vax2m	153	32	Table	Table	NNP
cord-311730-189vax2m	153	33	3	3	CD
cord-311730-189vax2m	153	34	)	)	-RRB-
cord-311730-189vax2m	153	35	.	.	.
cord-311730-189vax2m	154	1	The	the	DT
cord-311730-189vax2m	154	2	medical	medical	JJ
cord-311730-189vax2m	154	3	and	and	CC
cord-311730-189vax2m	154	4	scientific	scientific	JJ
cord-311730-189vax2m	154	5	community	community	NN
cord-311730-189vax2m	154	6	's	's	POS
cord-311730-189vax2m	154	7	collective	collective	JJ
cord-311730-189vax2m	154	8	response	response	NN
cord-311730-189vax2m	154	9	to	to	IN
cord-311730-189vax2m	154	10	the	the	DT
cord-311730-189vax2m	154	11	Covid-19	covid-19	JJ
cord-311730-189vax2m	154	12	pandemic	pandemic	NN
cord-311730-189vax2m	154	13	is	be	VBZ
cord-311730-189vax2m	154	14	predicated	predicate	VBN
cord-311730-189vax2m	154	15	on	on	IN
cord-311730-189vax2m	154	16	obtaining	obtain	VBG
cord-311730-189vax2m	154	17	the	the	DT
cord-311730-189vax2m	154	18	best	good	JJS
cord-311730-189vax2m	154	19	available	available	JJ
cord-311730-189vax2m	154	20	evidence	evidence	NN
cord-311730-189vax2m	154	21	from	from	IN
cord-311730-189vax2m	154	22	prevention	prevention	NN
cord-311730-189vax2m	154	23	,	,	,
cord-311730-189vax2m	154	24	treatment	treatment	NN
cord-311730-189vax2m	154	25	and	and	CC
cord-311730-189vax2m	154	26	overall	overall	JJ
cord-311730-189vax2m	154	27	management	management	NN
cord-311730-189vax2m	154	28	.	.	.
cord-311730-189vax2m	155	1	The	the	DT
cord-311730-189vax2m	155	2	evidence	evidence	NN
cord-311730-189vax2m	155	3	will	will	MD
cord-311730-189vax2m	155	4	come	come	VB
cord-311730-189vax2m	155	5	from	from	IN
cord-311730-189vax2m	155	6	well	well	RB
cord-311730-189vax2m	155	7	-	-	HYPH
cord-311730-189vax2m	155	8	designed	design	VBN
cord-311730-189vax2m	155	9	and	and	CC
cord-311730-189vax2m	155	10	conducted	conduct	VBN
cord-311730-189vax2m	155	11	clinical	clinical	JJ
cord-311730-189vax2m	155	12	trials	trial	NNS
cord-311730-189vax2m	155	13	.	.	.
cord-311730-189vax2m	156	1	It	-PRON-	PRP
cord-311730-189vax2m	156	2	is	be	VBZ
cord-311730-189vax2m	156	3	particularly	particularly	RB
cord-311730-189vax2m	156	4	important	important	JJ
cord-311730-189vax2m	156	5	in	in	IN
cord-311730-189vax2m	156	6	the	the	DT
cord-311730-189vax2m	156	7	context	context	NN
cord-311730-189vax2m	156	8	of	of	IN
cord-311730-189vax2m	156	9	current	current	JJ
cord-311730-189vax2m	156	10	events	event	NNS
cord-311730-189vax2m	156	11	to	to	TO
cord-311730-189vax2m	156	12	employ	employ	VB
cord-311730-189vax2m	156	13	a	a	DT
cord-311730-189vax2m	156	14	framework	framework	NN
cord-311730-189vax2m	156	15	that	that	WDT
cord-311730-189vax2m	156	16	can	can	MD
cord-311730-189vax2m	156	17	be	be	VB
cord-311730-189vax2m	156	18	applied	apply	VBN
cord-311730-189vax2m	156	19	and	and	CC
cord-311730-189vax2m	156	20	adapted	adapt	VBN
cord-311730-189vax2m	156	21	to	to	IN
cord-311730-189vax2m	156	22	environments	environment	NNS
cord-311730-189vax2m	156	23	and	and	CC
cord-311730-189vax2m	156	24	conditions	condition	NNS
cord-311730-189vax2m	156	25	,	,	,
cord-311730-189vax2m	156	26	maintain	maintain	VB
cord-311730-189vax2m	156	27	operational	operational	JJ
cord-311730-189vax2m	156	28	rigor	rigor	NN
cord-311730-189vax2m	156	29	and	and	CC
cord-311730-189vax2m	156	30	interpret	interpret	VB
cord-311730-189vax2m	156	31	the	the	DT
cord-311730-189vax2m	156	32	results	result	NNS
cord-311730-189vax2m	156	33	according	accord	VBG
cord-311730-189vax2m	156	34	to	to	IN
cord-311730-189vax2m	156	35	the	the	DT
cord-311730-189vax2m	156	36	data	datum	NNS
cord-311730-189vax2m	156	37	.	.	.
cord-311730-189vax2m	157	1	While	while	IN
cord-311730-189vax2m	157	2	all	all	DT
cord-311730-189vax2m	157	3	investigators	investigator	NNS
cord-311730-189vax2m	157	4	strive	strive	VBP
cord-311730-189vax2m	157	5	to	to	TO
cord-311730-189vax2m	157	6	answer	answer	VB
cord-311730-189vax2m	157	7	complex	complex	JJ
cord-311730-189vax2m	157	8	questions	question	NNS
cord-311730-189vax2m	157	9	about	about	IN
cord-311730-189vax2m	157	10	Covid-19	covid-19	NN
cord-311730-189vax2m	157	11	and	and	CC
cord-311730-189vax2m	157	12	make	make	VB
cord-311730-189vax2m	157	13	major	major	JJ
cord-311730-189vax2m	157	14	contributions	contribution	NNS
cord-311730-189vax2m	157	15	,	,	,
cord-311730-189vax2m	157	16	reporting	reporting	NN
cord-311730-189vax2m	157	17	and	and	CC
cord-311730-189vax2m	157	18	publishing	publish	VBG
cord-311730-189vax2m	157	19	negative	negative	JJ
cord-311730-189vax2m	157	20	trials	trial	NNS
cord-311730-189vax2m	157	21	are	be	VBP
cord-311730-189vax2m	157	22	equally	equally	RB
cord-311730-189vax2m	157	23	,	,	,
cord-311730-189vax2m	157	24	and	and	CC
cord-311730-189vax2m	157	25	not	not	RB
cord-311730-189vax2m	157	26	infrequently	infrequently	RB
cord-311730-189vax2m	157	27	,	,	,
cord-311730-189vax2m	157	28	more	more	RBR
cord-311730-189vax2m	157	29	important	important	JJ
cord-311730-189vax2m	157	30	than	than	IN
cord-311730-189vax2m	157	31	positive	positive	JJ
cord-311730-189vax2m	157	32	trials	trial	NNS
cord-311730-189vax2m	157	33	.	.	.
cord-311730-189vax2m	158	1	The	the	DT
cord-311730-189vax2m	158	2	R	r	NN
cord-311730-189vax2m	158	3	&	&	CC
cord-311730-189vax2m	158	4	D	D	NNP
cord-311730-189vax2m	158	5	Blueprint	Blueprint	NNP
cord-311730-189vax2m	158	6	working	work	VBG
cord-311730-189vax2m	158	7	group	group	NN
cord-311730-189vax2m	158	8	has	have	VBZ
cord-311730-189vax2m	158	9	advocated	advocate	VBN
cord-311730-189vax2m	158	10	for	for	IN
cord-311730-189vax2m	158	11	the	the	DT
cord-311730-189vax2m	158	12	use	use	NN
cord-311730-189vax2m	158	13	of	of	IN
cord-311730-189vax2m	158	14	"	"	``
cord-311730-189vax2m	158	15	core	core	NN
cord-311730-189vax2m	158	16	protocols	protocol	NNS
cord-311730-189vax2m	158	17	"	"	''
cord-311730-189vax2m	158	18	when	when	WRB
cord-311730-189vax2m	158	19	designing	design	VBG
cord-311730-189vax2m	158	20	clinical	clinical	JJ
cord-311730-189vax2m	158	21	trials	trial	NNS
cord-311730-189vax2m	158	22	during	during	IN
cord-311730-189vax2m	158	23	public	public	JJ
cord-311730-189vax2m	158	24	health	health	NN
cord-311730-189vax2m	158	25	emergencies	emergency	NNS
cord-311730-189vax2m	158	26	like	like	IN
cord-311730-189vax2m	158	27	Covid-19	Covid-19	NNP
cord-311730-189vax2m	158	28	[	[	-LRB-
cord-311730-189vax2m	158	29	37	37	CD
cord-311730-189vax2m	158	30	,	,	,
cord-311730-189vax2m	158	31	38	38	CD
cord-311730-189vax2m	158	32	]	]	-RRB-
cord-311730-189vax2m	158	33	.	.	.
cord-311730-189vax2m	159	1	In	in	IN
cord-311730-189vax2m	159	2	addition	addition	NN
cord-311730-189vax2m	159	3	to	to	IN
cord-311730-189vax2m	159	4	providing	provide	VBG
cord-311730-189vax2m	159	5	a	a	DT
cord-311730-189vax2m	159	6	strong	strong	JJ
cord-311730-189vax2m	159	7	research	research	NN
cord-311730-189vax2m	159	8	platform	platform	NN
cord-311730-189vax2m	159	9	in	in	IN
cord-311730-189vax2m	159	10	the	the	DT
cord-311730-189vax2m	159	11	midst	midst	NN
cord-311730-189vax2m	159	12	of	of	IN
cord-311730-189vax2m	159	13	highly	highly	RB
cord-311730-189vax2m	159	14	dynamic	dynamic	JJ
cord-311730-189vax2m	159	15	settings	setting	NNS
cord-311730-189vax2m	159	16	encountered	encounter	VBN
cord-311730-189vax2m	159	17	during	during	IN
cord-311730-189vax2m	159	18	public	public	JJ
cord-311730-189vax2m	159	19	health	health	NN
cord-311730-189vax2m	159	20	emergencies	emergency	NNS
cord-311730-189vax2m	159	21	,	,	,
cord-311730-189vax2m	159	22	core	core	NN
cord-311730-189vax2m	159	23	or	or	CC
cord-311730-189vax2m	159	24	master	master	NN
cord-311730-189vax2m	159	25	protocols	protocol	NNS
cord-311730-189vax2m	159	26	,	,	,
cord-311730-189vax2m	159	27	inclusion	inclusion	NN
cord-311730-189vax2m	159	28	of	of	IN
cord-311730-189vax2m	159	29	independent	independent	JJ
cord-311730-189vax2m	159	30	monitoring	monitoring	NN
cord-311730-189vax2m	159	31	committees	committee	NNS
cord-311730-189vax2m	159	32	,	,	,
cord-311730-189vax2m	159	33	"	"	''
cord-311730-189vax2m	159	34	pause	pause	VB
cord-311730-189vax2m	159	35	or	or	CC
cord-311730-189vax2m	159	36	stopping	stop	VBG
cord-311730-189vax2m	159	37	"	"	''
cord-311730-189vax2m	159	38	rules	rule	NNS
cord-311730-189vax2m	159	39	,	,	,
cord-311730-189vax2m	159	40	publication	publication	NN
cord-311730-189vax2m	159	41	metric	metric	JJ
cord-311730-189vax2m	159	42	requirements	requirement	NNS
cord-311730-189vax2m	159	43	and	and	CC
cord-311730-189vax2m	159	44	clear	clear	JJ
cord-311730-189vax2m	159	45	ground	ground	NN
cord-311730-189vax2m	159	46	rules	rule	NNS
cord-311730-189vax2m	159	47	for	for	IN
cord-311730-189vax2m	159	48	public	public	JJ
cord-311730-189vax2m	159	49	messaging	messaging	NN
cord-311730-189vax2m	159	50	are	be	VBP
cord-311730-189vax2m	159	51	needed	need	VBN
cord-311730-189vax2m	159	52	[	[	-LRB-
cord-311730-189vax2m	159	53	38	38	CD
cord-311730-189vax2m	159	54	]	]	-RRB-
cord-311730-189vax2m	159	55	.	.	.
cord-311730-189vax2m	160	1	Among	among	IN
cord-311730-189vax2m	160	2	the	the	DT
cord-311730-189vax2m	160	3	many	many	JJ
cord-311730-189vax2m	160	4	attractive	attractive	JJ
cord-311730-189vax2m	160	5	features	feature	NNS
cord-311730-189vax2m	160	6	of	of	IN
cord-311730-189vax2m	160	7	core	core	NN
cord-311730-189vax2m	160	8	protocols	protocol	NNS
cord-311730-189vax2m	160	9	,	,	,
cord-311730-189vax2m	160	10	their	-PRON-	PRP$
cord-311730-189vax2m	160	11	inherent	inherent	JJ
cord-311730-189vax2m	160	12	design	design	NN
cord-311730-189vax2m	160	13	is	be	VBZ
cord-311730-189vax2m	160	14	collaborative	collaborative	JJ
cord-311730-189vax2m	160	15	in	in	IN
cord-311730-189vax2m	160	16	nature	nature	NN
cord-311730-189vax2m	160	17	,	,	,
cord-311730-189vax2m	160	18	engaging	engage	VBG
cord-311730-189vax2m	160	19	investigators	investigator	NNS
cord-311730-189vax2m	160	20	and	and	CC
cord-311730-189vax2m	160	21	stakeholders	stakeholder	NNS
cord-311730-189vax2m	160	22	early	early	RB
cord-311730-189vax2m	160	23	in	in	IN
cord-311730-189vax2m	160	24	the	the	DT
cord-311730-189vax2m	160	25	public	public	JJ
cord-311730-189vax2m	160	26	health	health	NN
cord-311730-189vax2m	160	27	emergency	emergency	NN
cord-311730-189vax2m	160	28	to	to	TO
cord-311730-189vax2m	160	29	determine	determine	VB
cord-311730-189vax2m	160	30	the	the	DT
cord-311730-189vax2m	160	31	most	most	RBS
cord-311730-189vax2m	160	32	important	important	JJ
cord-311730-189vax2m	160	33	research	research	NN
cord-311730-189vax2m	160	34	question(s	question(s	NNP
cord-311730-189vax2m	160	35	)	)	-RRB-
cord-311730-189vax2m	160	36	,	,	,
cord-311730-189vax2m	160	37	optimal	optimal	JJ
cord-311730-189vax2m	160	38	study	study	NN
cord-311730-189vax2m	160	39	design	design	NN
cord-311730-189vax2m	160	40	,	,	,
cord-311730-189vax2m	160	41	ethic	ethic	NN
cord-311730-189vax2m	160	42	and	and	CC
cord-311730-189vax2m	160	43	regulatory	regulatory	JJ
cord-311730-189vax2m	160	44	needs	need	NNS
cord-311730-189vax2m	160	45	,	,	,
cord-311730-189vax2m	160	46	funding	funding	NN
cord-311730-189vax2m	160	47	sources	source	NNS
cord-311730-189vax2m	160	48	,	,	,
cord-311730-189vax2m	160	49	country	country	NN
cord-311730-189vax2m	160	50	health	health	NN
cord-311730-189vax2m	160	51	authority	authority	NN
cord-311730-189vax2m	160	52	and	and	CC
cord-311730-189vax2m	160	53	governmental	governmental	JJ
cord-311730-189vax2m	160	54	integration	integration	NN
cord-311730-189vax2m	160	55	,	,	,
cord-311730-189vax2m	160	56	communications	communication	NNS
cord-311730-189vax2m	160	57	,	,	,
cord-311730-189vax2m	160	58	data	datum	NNS
cord-311730-189vax2m	160	59	security	security	NN
cord-311730-189vax2m	160	60	,	,	,
cord-311730-189vax2m	160	61	oversight	oversight	NN
cord-311730-189vax2m	160	62	and	and	CC
cord-311730-189vax2m	160	63	clinical	clinical	JJ
cord-311730-189vax2m	160	64	operations	operation	NNS
cord-311730-189vax2m	160	65	.	.	.
cord-311730-189vax2m	161	1	An	an	DT
cord-311730-189vax2m	161	2	ability	ability	NN
cord-311730-189vax2m	161	3	to	to	TO
cord-311730-189vax2m	161	4	conduct	conduct	VB
cord-311730-189vax2m	161	5	high	high	JJ
cord-311730-189vax2m	161	6	quality	quality	NN
cord-311730-189vax2m	161	7	research	research	NN
cord-311730-189vax2m	161	8	that	that	WDT
cord-311730-189vax2m	161	9	is	be	VBZ
cord-311730-189vax2m	161	10	valuable	valuable	JJ
cord-311730-189vax2m	161	11	and	and	CC
cord-311730-189vax2m	161	12	worthy	worthy	JJ
cord-311730-189vax2m	161	13	of	of	IN
cord-311730-189vax2m	161	14	serious	serious	JJ
cord-311730-189vax2m	161	15	consideration	consideration	NN
cord-311730-189vax2m	161	16	by	by	IN
cord-311730-189vax2m	161	17	the	the	DT
cord-311730-189vax2m	161	18	scientific	scientific	JJ
cord-311730-189vax2m	161	19	community	community	NN
cord-311730-189vax2m	161	20	requires	require	VBZ
cord-311730-189vax2m	161	21	a	a	DT
cord-311730-189vax2m	161	22	research	research	NN
cord-311730-189vax2m	161	23	quality	quality	NN
cord-311730-189vax2m	161	24	framework	framework	NN
cord-311730-189vax2m	161	25	(	(	-LRB-
cord-311730-189vax2m	161	26	RQF	RQF	NNP
cord-311730-189vax2m	161	27	)	)	-RRB-
cord-311730-189vax2m	161	28	.	.	.
cord-311730-189vax2m	162	1	While	while	IN
cord-311730-189vax2m	162	2	experienced	experienced	JJ
cord-311730-189vax2m	162	3	investigators	investigator	NNS
cord-311730-189vax2m	162	4	have	have	VBP
cord-311730-189vax2m	162	5	been	be	VBN
cord-311730-189vax2m	162	6	using	use	VBG
cord-311730-189vax2m	162	7	RQF	RQF	NNP
cord-311730-189vax2m	162	8	's	's	POS
cord-311730-189vax2m	162	9	for	for	IN
cord-311730-189vax2m	162	10	many	many	JJ
cord-311730-189vax2m	162	11	years	year	NNS
cord-311730-189vax2m	162	12	,	,	,
cord-311730-189vax2m	162	13	a	a	DT
cord-311730-189vax2m	162	14	reminder	reminder	NN
cord-311730-189vax2m	162	15	of	of	IN
cord-311730-189vax2m	162	16	its	-PRON-	PRP$
cord-311730-189vax2m	162	17	vital	vital	JJ
cord-311730-189vax2m	162	18	role	role	NN
cord-311730-189vax2m	162	19	and	and	CC
cord-311730-189vax2m	162	20	component	component	NN
cord-311730-189vax2m	162	21	parts	part	NNS
cord-311730-189vax2m	162	22	is	be	VBZ
cord-311730-189vax2m	162	23	fitting	fit	VBG
cord-311730-189vax2m	162	24	given	give	VBN
cord-311730-189vax2m	162	25	the	the	DT
cord-311730-189vax2m	162	26	Covid-19	covid-19	NN
cord-311730-189vax2m	162	27	pandemic	pandemic	NN
cord-311730-189vax2m	162	28	and	and	CC
cord-311730-189vax2m	162	29	desire	desire	NN
cord-311730-189vax2m	162	30	for	for	IN
cord-311730-189vax2m	162	31	study	study	NN
cord-311730-189vax2m	162	32	results	result	NNS
cord-311730-189vax2m	162	33	to	to	TO
cord-311730-189vax2m	162	34	emerge	emerge	VB
cord-311730-189vax2m	162	35	as	as	RB
cord-311730-189vax2m	162	36	rapidly	rapidly	RB
cord-311730-189vax2m	162	37	as	as	IN
cord-311730-189vax2m	162	38	possible	possible	JJ
cord-311730-189vax2m	162	39	.	.	.
cord-311730-189vax2m	163	1	The	the	DT
cord-311730-189vax2m	163	2	key	key	JJ
cord-311730-189vax2m	163	3	processes	process	NNS
cord-311730-189vax2m	163	4	,	,	,
cord-311730-189vax2m	163	5	metrics	metric	NNS
cord-311730-189vax2m	163	6	and	and	CC
cord-311730-189vax2m	163	7	tenets	tenet	NNS
cord-311730-189vax2m	163	8	of	of	IN
cord-311730-189vax2m	163	9	a	a	DT
cord-311730-189vax2m	163	10	RQF	rqf	NN
cord-311730-189vax2m	163	11	are	be	VBP
cord-311730-189vax2m	163	12	as	as	IN
cord-311730-189vax2m	163	13	follows	follow	VBZ
cord-311730-189vax2m	163	14	:	:	:
cord-311730-189vax2m	164	1	•	•	NNP
cord-311730-189vax2m	165	1	Data	data	NN
cord-311730-189vax2m	165	2	provenance	provenance	NN
cord-311730-189vax2m	165	3	(	(	-LRB-
cord-311730-189vax2m	165	4	internal	internal	JJ
cord-311730-189vax2m	165	5	and	and	CC
cord-311730-189vax2m	165	6	external	external	JJ
cord-311730-189vax2m	165	7	reproducible	reproducible	NN
cord-311730-189vax2m	165	8	of	of	IN
cord-311730-189vax2m	165	9	the	the	DT
cord-311730-189vax2m	165	10	findings	finding	NNS
cord-311730-189vax2m	165	11	)	)	-RRB-
cord-311730-189vax2m	166	1	•	•	NNP
cord-311730-189vax2m	167	1	Quantitative	quantitative	JJ
cord-311730-189vax2m	167	2	expertise	expertise	NN
cord-311730-189vax2m	167	3	(	(	-LRB-
cord-311730-189vax2m	167	4	applied	apply	VBN
cord-311730-189vax2m	167	5	under	under	IN
cord-311730-189vax2m	167	6	proper	proper	JJ
cord-311730-189vax2m	167	7	standards	standard	NNS
cord-311730-189vax2m	167	8	to	to	IN
cord-311730-189vax2m	167	9	the	the	DT
cord-311730-189vax2m	167	10	design	design	NN
cord-311730-189vax2m	167	11	,	,	,
cord-311730-189vax2m	167	12	conduct	conduct	VB
cord-311730-189vax2m	167	13	analysis	analysis	NN
cord-311730-189vax2m	167	14	and	and	CC
cord-311730-189vax2m	167	15	presentation	presentation	NN
cord-311730-189vax2m	167	16	of	of	IN
cord-311730-189vax2m	167	17	the	the	DT
cord-311730-189vax2m	167	18	results	result	NNS
cord-311730-189vax2m	167	19	)	)	-RRB-
cord-311730-189vax2m	168	1	•	•	NNP
cord-311730-189vax2m	168	2	Governance	Governance	NNP
cord-311730-189vax2m	168	3	and	and	CC
cord-311730-189vax2m	168	4	oversight	oversight	NN
cord-311730-189vax2m	169	1	•	•	NNP
cord-311730-189vax2m	170	1	Special	special	JJ
cord-311730-189vax2m	170	2	review	review	NN
cord-311730-189vax2m	170	3	of	of	IN
cord-311730-189vax2m	170	4	potential	potential	JJ
cord-311730-189vax2m	170	5	conflicts	conflict	NNS
cord-311730-189vax2m	170	6	of	of	IN
cord-311730-189vax2m	170	7	interests	interest	NNS
cord-311730-189vax2m	171	1	•	•	NNP
cord-311730-189vax2m	172	1	Comprehensive	comprehensive	JJ
cord-311730-189vax2m	172	2	vetting	vetting	NN
cord-311730-189vax2m	172	3	,	,	,
cord-311730-189vax2m	172	4	implementation	implementation	NN
cord-311730-189vax2m	172	5	and	and	CC
cord-311730-189vax2m	172	6	assessment	assessment	NN
cord-311730-189vax2m	172	7	of	of	IN
cord-311730-189vax2m	172	8	research	research	NN
cord-311730-189vax2m	172	9	practices	practice	NNS
cord-311730-189vax2m	172	10	based	base	VBN
cord-311730-189vax2m	172	11	on	on	IN
cord-311730-189vax2m	172	12	instrumental	instrumental	JJ
cord-311730-189vax2m	172	13	,	,	,
cord-311730-189vax2m	172	14	research	research	NN
cord-311730-189vax2m	172	15	network	network	NN
cord-311730-189vax2m	172	16	or	or	CC
cord-311730-189vax2m	172	17	organizational	organizational	JJ
cord-311730-189vax2m	172	18	standards	standard	NNS
cord-311730-189vax2m	173	1	•	•	NNP
cord-311730-189vax2m	174	1	Transparency	transparency	NN
cord-311730-189vax2m	174	2	of	of	IN
cord-311730-189vax2m	174	3	processes	process	NNS
cord-311730-189vax2m	174	4	.	.	.
cord-311730-189vax2m	175	1	1	1	LS
cord-311730-189vax2m	175	2	.	.	.
cord-311730-189vax2m	176	1	Mobilize	mobilize	VB
cord-311730-189vax2m	176	2	research	research	NN
cord-311730-189vax2m	176	3	on	on	IN
cord-311730-189vax2m	176	4	rapid	rapid	JJ
cord-311730-189vax2m	176	5	point	point	NN
cord-311730-189vax2m	176	6	of	of	IN
cord-311730-189vax2m	176	7	care	care	NN
cord-311730-189vax2m	176	8	diagnostics	diagnostic	NNS
cord-311730-189vax2m	176	9	for	for	IN
cord-311730-189vax2m	176	10	use	use	NN
cord-311730-189vax2m	176	11	at	at	IN
cord-311730-189vax2m	176	12	the	the	DT
cord-311730-189vax2m	176	13	community	community	NN
cord-311730-189vax2m	176	14	level	level	NN
cord-311730-189vax2m	176	15	-	-	:
cord-311730-189vax2m	176	16	this	this	DT
cord-311730-189vax2m	176	17	is	be	VBZ
cord-311730-189vax2m	176	18	critical	critical	JJ
cord-311730-189vax2m	176	19	to	to	TO
cord-311730-189vax2m	176	20	be	be	VB
cord-311730-189vax2m	176	21	able	able	JJ
cord-311730-189vax2m	176	22	to	to	TO
cord-311730-189vax2m	176	23	quickly	quickly	RB
cord-311730-189vax2m	176	24	identify	identify	VB
cord-311730-189vax2m	176	25	sick	sick	JJ
cord-311730-189vax2m	176	26	people	people	NNS
cord-311730-189vax2m	176	27	,	,	,
cord-311730-189vax2m	176	28	treat	treat	VB
cord-311730-189vax2m	176	29	them	-PRON-	PRP
cord-311730-189vax2m	176	30	and	and	CC
cord-311730-189vax2m	176	31	better	well	JJR
cord-311730-189vax2m	176	32	estimate	estimate	VB
cord-311730-189vax2m	176	33	how	how	WRB
cord-311730-189vax2m	176	34	widely	widely	RB
cord-311730-189vax2m	176	35	the	the	DT
cord-311730-189vax2m	176	36	virus	virus	NN
cord-311730-189vax2m	176	37	has	have	VBZ
cord-311730-189vax2m	176	38	spread	spread	VBN
cord-311730-189vax2m	176	39	2	2	CD
cord-311730-189vax2m	176	40	.	.	.
cord-311730-189vax2m	177	1	Immediately	immediately	RB
cord-311730-189vax2m	177	2	assess	assess	VB
cord-311730-189vax2m	177	3	available	available	JJ
cord-311730-189vax2m	177	4	data	datum	NNS
cord-311730-189vax2m	177	5	to	to	TO
cord-311730-189vax2m	177	6	learn	learn	VB
cord-311730-189vax2m	177	7	what	what	WDT
cord-311730-189vax2m	177	8	standard	standard	NN
cord-311730-189vax2m	177	9	of	of	IN
cord-311730-189vax2m	177	10	care	care	NN
cord-311730-189vax2m	177	11	approaches	approach	NNS
cord-311730-189vax2m	177	12	from	from	IN
cord-311730-189vax2m	177	13	China	China	NNP
cord-311730-189vax2m	177	14	and	and	CC
cord-311730-189vax2m	177	15	elsewhere	elsewhere	RB
cord-311730-189vax2m	177	16	are	be	VBP
cord-311730-189vax2m	177	17	the	the	DT
cord-311730-189vax2m	177	18	most	most	RBS
cord-311730-189vax2m	177	19	effective	effective	JJ
cord-311730-189vax2m	177	20	-	-	:
cord-311730-189vax2m	177	21	there	there	EX
cord-311730-189vax2m	177	22	is	be	VBZ
cord-311730-189vax2m	177	23	an	an	DT
cord-311730-189vax2m	177	24	imperative	imperative	NN
cord-311730-189vax2m	177	25	to	to	TO
cord-311730-189vax2m	177	26	optimize	optimize	VB
cord-311730-189vax2m	177	27	standard	standard	NN
cord-311730-189vax2m	177	28	of	of	IN
cord-311730-189vax2m	177	29	care	care	NN
cord-311730-189vax2m	177	30	given	give	VBN
cord-311730-189vax2m	177	31	to	to	IN
cord-311730-189vax2m	177	32	patients	patient	NNS
cord-311730-189vax2m	177	33	at	at	IN
cord-311730-189vax2m	177	34	different	different	JJ
cord-311730-189vax2m	177	35	stages	stage	NNS
cord-311730-189vax2m	177	36	of	of	IN
cord-311730-189vax2m	177	37	the	the	DT
cord-311730-189vax2m	177	38	disease	disease	NN
cord-311730-189vax2m	177	39	and	and	CC
cord-311730-189vax2m	177	40	take	take	VB
cord-311730-189vax2m	177	41	advantages	advantage	NNS
cord-311730-189vax2m	177	42	of	of	IN
cord-311730-189vax2m	177	43	all	all	DT
cord-311730-189vax2m	177	44	available	available	JJ
cord-311730-189vax2m	177	45	technological	technological	JJ
cord-311730-189vax2m	177	46	innovations	innovation	NNS
cord-311730-189vax2m	177	47	to	to	TO
cord-311730-189vax2m	177	48	improve	improve	VB
cord-311730-189vax2m	177	49	survival	survival	NN
cord-311730-189vax2m	177	50	and	and	CC
cord-311730-189vax2m	177	51	recovery	recovery	NN
cord-311730-189vax2m	177	52	3	3	CD
cord-311730-189vax2m	177	53	.	.	.
cord-311730-189vax2m	178	1	Evaluate	evaluate	VB
cord-311730-189vax2m	178	2	as	as	RB
cord-311730-189vax2m	178	3	fast	fast	RB
cord-311730-189vax2m	178	4	as	as	IN
cord-311730-189vax2m	178	5	possible	possible	JJ
cord-311730-189vax2m	178	6	the	the	DT
cord-311730-189vax2m	178	7	effect	effect	NN
cord-311730-189vax2m	178	8	of	of	IN
cord-311730-189vax2m	178	9	adjunctive	adjunctive	JJ
cord-311730-189vax2m	178	10	and	and	CC
cord-311730-189vax2m	178	11	supportive	supportive	JJ
cord-311730-189vax2m	178	12	therapies-	therapies-	NN
cord-311730-189vax2m	179	1	The	the	DT
cord-311730-189vax2m	179	2	global	global	JJ
cord-311730-189vax2m	179	3	research	research	NN
cord-311730-189vax2m	179	4	community	community	NN
cord-311730-189vax2m	179	5	need	need	VBP
cord-311730-189vax2m	179	6	to	to	TO
cord-311730-189vax2m	179	7	understand	understand	VB
cord-311730-189vax2m	179	8	what	what	WP
cord-311730-189vax2m	179	9	other	other	JJ
cord-311730-189vax2m	179	10	adjunctive	adjunctive	JJ
cord-311730-189vax2m	179	11	treatments	treatment	NNS
cord-311730-189vax2m	179	12	than	than	IN
cord-311730-189vax2m	179	13	currently	currently	RB
cord-311730-189vax2m	179	14	being	be	VBG
cord-311730-189vax2m	179	15	used	use	VBN
cord-311730-189vax2m	179	16	are	be	VBP
cord-311730-189vax2m	179	17	at	at	IN
cord-311730-189vax2m	179	18	our	-PRON-	PRP$
cord-311730-189vax2m	179	19	disposal	disposal	NN
cord-311730-189vax2m	179	20	that	that	WDT
cord-311730-189vax2m	179	21	may	may	MD
cord-311730-189vax2m	179	22	help	help	VB
cord-311730-189vax2m	179	23	with	with	IN
cord-311730-189vax2m	179	24	the	the	DT
cord-311730-189vax2m	179	25	standard	standard	NN
cord-311730-189vax2m	179	26	of	of	IN
cord-311730-189vax2m	179	27	care	care	NN
cord-311730-189vax2m	179	28	provided	provide	VBN
cord-311730-189vax2m	179	29	to	to	IN
cord-311730-189vax2m	179	30	patients	patient	NNS
cord-311730-189vax2m	179	31	,	,	,
cord-311730-189vax2m	179	32	including	include	VBG
cord-311730-189vax2m	179	33	the	the	DT
cord-311730-189vax2m	179	34	quick	quick	JJ
cord-311730-189vax2m	179	35	evaluation	evaluation	NN
cord-311730-189vax2m	179	36	of	of	IN
cord-311730-189vax2m	179	37	interventions	intervention	NNS
cord-311730-189vax2m	179	38	such	such	JJ
cord-311730-189vax2m	179	39	as	as	IN
cord-311730-189vax2m	179	40	steroids	steroid	NNS
cord-311730-189vax2m	179	41	and	and	CC
cord-311730-189vax2m	179	42	high	high	JJ
cord-311730-189vax2m	179	43	flow	flow	NN
cord-311730-189vax2m	179	44	oxygen	oxygen	NN
cord-311730-189vax2m	179	45	4	4	CD
cord-311730-189vax2m	179	46	.	.	.
cord-311730-189vax2m	180	1	Optimize	optimize	VB
cord-311730-189vax2m	180	2	use	use	NN
cord-311730-189vax2m	180	3	of	of	IN
cord-311730-189vax2m	180	4	protective	protective	JJ
cord-311730-189vax2m	180	5	equipment	equipment	NN
cord-311730-189vax2m	180	6	and	and	CC
cord-311730-189vax2m	180	7	other	other	JJ
cord-311730-189vax2m	180	8	infection	infection	NN
cord-311730-189vax2m	180	9	prevention	prevention	NN
cord-311730-189vax2m	180	10	and	and	CC
cord-311730-189vax2m	180	11	control	control	NN
cord-311730-189vax2m	180	12	measures	measure	NNS
cord-311730-189vax2m	180	13	in	in	IN
cord-311730-189vax2m	180	14	health	health	NN
cord-311730-189vax2m	180	15	care	care	NN
cord-311730-189vax2m	180	16	and	and	CC
cord-311730-189vax2m	180	17	community	community	NN
cord-311730-189vax2m	180	18	settings	setting	NNS
cord-311730-189vax2m	181	1	-It	-It	:
cord-311730-189vax2m	181	2	is	be	VBZ
cord-311730-189vax2m	181	3	critical	critical	JJ
cord-311730-189vax2m	181	4	to	to	TO
cord-311730-189vax2m	181	5	protect	protect	VB
cord-311730-189vax2m	181	6	health	health	NN
cord-311730-189vax2m	181	7	care	care	NN
cord-311730-189vax2m	181	8	workers	worker	NNS
cord-311730-189vax2m	181	9	and	and	CC
cord-311730-189vax2m	181	10	the	the	DT
cord-311730-189vax2m	181	11	community	community	NN
cord-311730-189vax2m	181	12	from	from	IN
cord-311730-189vax2m	181	13	transmission	transmission	NN
cord-311730-189vax2m	181	14	and	and	CC
cord-311730-189vax2m	181	15	create	create	VB
cord-311730-189vax2m	181	16	a	a	DT
cord-311730-189vax2m	181	17	safe	safe	JJ
cord-311730-189vax2m	181	18	working	working	NN
cord-311730-189vax2m	181	19	environment	environment	NN
cord-311730-189vax2m	181	20	5	5	CD
cord-311730-189vax2m	181	21	.	.	.
cord-311730-189vax2m	182	1	Review	review	VB
cord-311730-189vax2m	182	2	all	all	DT
cord-311730-189vax2m	182	3	evidence	evidence	NN
cord-311730-189vax2m	182	4	available	available	JJ
cord-311730-189vax2m	182	5	to	to	TO
cord-311730-189vax2m	182	6	identify	identify	VB
cord-311730-189vax2m	182	7	animal	animal	NN
cord-311730-189vax2m	182	8	host(s	host(s	NNP
cord-311730-189vax2m	182	9	)	)	-RRB-
cord-311730-189vax2m	182	10	,	,	,
cord-311730-189vax2m	182	11	to	to	TO
cord-311730-189vax2m	182	12	prevent	prevent	VB
cord-311730-189vax2m	182	13	continued	continued	JJ
cord-311730-189vax2m	182	14	spill	spill	NN
cord-311730-189vax2m	182	15	over	over	RP
cord-311730-189vax2m	182	16	and	and	CC
cord-311730-189vax2m	182	17	to	to	TO
cord-311730-189vax2m	182	18	better	better	RB
cord-311730-189vax2m	182	19	understand	understand	VB
cord-311730-189vax2m	182	20	the	the	DT
cord-311730-189vax2m	182	21	virus	virus	NN
cord-311730-189vax2m	182	22	transmissibility	transmissibility	NN
cord-311730-189vax2m	182	23	in	in	IN
cord-311730-189vax2m	182	24	different	different	JJ
cord-311730-189vax2m	182	25	contexts	context	NNS
cord-311730-189vax2m	182	26	over	over	IN
cord-311730-189vax2m	182	27	time	time	NN
cord-311730-189vax2m	182	28	,	,	,
cord-311730-189vax2m	182	29	the	the	DT
cord-311730-189vax2m	182	30	severity	severity	NN
cord-311730-189vax2m	182	31	of	of	IN
cord-311730-189vax2m	182	32	disease	disease	NN
cord-311730-189vax2m	182	33	and	and	CC
cord-311730-189vax2m	182	34	who	who	WP
cord-311730-189vax2m	182	35	is	be	VBZ
cord-311730-189vax2m	182	36	more	more	RBR
cord-311730-189vax2m	182	37	susceptible	susceptible	JJ
cord-311730-189vax2m	182	38	to	to	IN
cord-311730-189vax2m	182	39	infection	infection	NN
cord-311730-189vax2m	183	1	-Understanding	-understande	VBG
cord-311730-189vax2m	183	2	transmission	transmission	NN
cord-311730-189vax2m	183	3	dynamics	dynamic	NNS
cord-311730-189vax2m	183	4	would	would	MD
cord-311730-189vax2m	183	5	help	help	VB
cord-311730-189vax2m	183	6	us	-PRON-	PRP
cord-311730-189vax2m	183	7	appreciate	appreciate	VB
cord-311730-189vax2m	183	8	the	the	DT
cord-311730-189vax2m	183	9	full	full	JJ
cord-311730-189vax2m	183	10	spectrum	spectrum	NN
cord-311730-189vax2m	183	11	of	of	IN
cord-311730-189vax2m	183	12	the	the	DT
cord-311730-189vax2m	183	13	disease	disease	NN
cord-311730-189vax2m	183	14	,	,	,
cord-311730-189vax2m	183	15	in	in	IN
cord-311730-189vax2m	183	16	terms	term	NNS
cord-311730-189vax2m	183	17	of	of	IN
cord-311730-189vax2m	183	18	at	at	IN
cord-311730-189vax2m	183	19	risk	risk	NN
cord-311730-189vax2m	183	20	groups	group	NNS
cord-311730-189vax2m	183	21	,	,	,
cord-311730-189vax2m	183	22	and	and	CC
cord-311730-189vax2m	183	23	conditions	condition	NNS
cord-311730-189vax2m	183	24	that	that	WDT
cord-311730-189vax2m	183	25	make	make	VBP
cord-311730-189vax2m	183	26	the	the	DT
cord-311730-189vax2m	183	27	disease	disease	NN
cord-311730-189vax2m	183	28	more	more	RBR
cord-311730-189vax2m	183	29	severe	severe	JJ
cord-311730-189vax2m	183	30	as	as	RB
cord-311730-189vax2m	183	31	well	well	RB
cord-311730-189vax2m	183	32	as	as	IN
cord-311730-189vax2m	183	33	the	the	DT
cord-311730-189vax2m	183	34	effectiveness	effectiveness	NN
cord-311730-189vax2m	183	35	of	of	IN
cord-311730-189vax2m	183	36	certain	certain	JJ
cord-311730-189vax2m	183	37	public	public	JJ
cord-311730-189vax2m	183	38	health	health	NN
cord-311730-189vax2m	183	39	interventions	intervention	NNS
cord-311730-189vax2m	183	40	6	6	CD
cord-311730-189vax2m	183	41	.	.	.
cord-311730-189vax2m	184	1	Accelerate	accelerate	VB
cord-311730-189vax2m	184	2	the	the	DT
cord-311730-189vax2m	184	3	evaluation	evaluation	NN
cord-311730-189vax2m	184	4	of	of	IN
cord-311730-189vax2m	184	5	investigational	investigational	JJ
cord-311730-189vax2m	184	6	therapeutics	therapeutic	NNS
cord-311730-189vax2m	184	7	and	and	CC
cord-311730-189vax2m	184	8	vaccines	vaccine	NNS
cord-311730-189vax2m	184	9	by	by	IN
cord-311730-189vax2m	184	10	using	use	VBG
cord-311730-189vax2m	184	11	"	"	``
cord-311730-189vax2m	184	12	Master	Master	NNP
cord-311730-189vax2m	184	13	Protocols"-Rapidly	Protocols"-Rapidly	NNP
cord-311730-189vax2m	184	14	developing	develop	VBG
cord-311730-189vax2m	184	15	master	master	NN
cord-311730-189vax2m	184	16	protocols	protocol	NNS
cord-311730-189vax2m	184	17	for	for	IN
cord-311730-189vax2m	184	18	clinical	clinical	JJ
cord-311730-189vax2m	184	19	trials	trial	NNS
cord-311730-189vax2m	184	20	will	will	MD
cord-311730-189vax2m	184	21	accelerate	accelerate	VB
cord-311730-189vax2m	184	22	the	the	DT
cord-311730-189vax2m	184	23	potential	potential	NN
cord-311730-189vax2m	184	24	to	to	TO
cord-311730-189vax2m	184	25	assess	assess	VB
cord-311730-189vax2m	184	26	what	what	WP
cord-311730-189vax2m	184	27	works	work	VBZ
cord-311730-189vax2m	184	28	and	and	CC
cord-311730-189vax2m	184	29	what	what	WP
cord-311730-189vax2m	184	30	does	do	VBZ
cord-311730-189vax2m	184	31	not	not	RB
cord-311730-189vax2m	184	32	,	,	,
cord-311730-189vax2m	184	33	improve	improve	VB
cord-311730-189vax2m	184	34	collaboration	collaboration	NN
cord-311730-189vax2m	184	35	and	and	CC
cord-311730-189vax2m	184	36	comparison	comparison	NN
cord-311730-189vax2m	184	37	across	across	IN
cord-311730-189vax2m	184	38	different	different	JJ
cord-311730-189vax2m	184	39	studies	study	NNS
cord-311730-189vax2m	184	40	,	,	,
cord-311730-189vax2m	184	41	streamline	streamline	VB
cord-311730-189vax2m	184	42	ethics	ethic	NNS
cord-311730-189vax2m	184	43	review	review	NN
cord-311730-189vax2m	184	44	and	and	CC
cord-311730-189vax2m	184	45	optimize	optimize	VB
cord-311730-189vax2m	184	46	the	the	DT
cord-311730-189vax2m	184	47	evaluation	evaluation	NN
cord-311730-189vax2m	184	48	of	of	IN
cord-311730-189vax2m	184	49	new	new	JJ
cord-311730-189vax2m	184	50	investigational	investigational	JJ
cord-311730-189vax2m	184	51	drugs	drug	NNS
cord-311730-189vax2m	184	52	,	,	,
cord-311730-189vax2m	184	53	vaccines	vaccine	NNS
cord-311730-189vax2m	184	54	and	and	CC
cord-311730-189vax2m	184	55	diagnostics	diagnostic	NNS
cord-311730-189vax2m	184	56	7	7	CD
cord-311730-189vax2m	184	57	.	.	.
cord-311730-189vax2m	185	1	Maintain	maintain	VB
cord-311730-189vax2m	185	2	a	a	DT
cord-311730-189vax2m	185	3	high	high	JJ
cord-311730-189vax2m	185	4	degree	degree	NN
cord-311730-189vax2m	185	5	of	of	IN
cord-311730-189vax2m	185	6	communication	communication	NN
cord-311730-189vax2m	185	7	and	and	CC
cord-311730-189vax2m	185	8	interaction	interaction	NN
cord-311730-189vax2m	185	9	among	among	IN
cord-311730-189vax2m	185	10	funders	funder	NNS
cord-311730-189vax2m	185	11	so	so	IN
cord-311730-189vax2m	185	12	that	that	IN
cord-311730-189vax2m	185	13	critical	critical	JJ
cord-311730-189vax2m	185	14	research	research	NN
cord-311730-189vax2m	185	15	is	be	VBZ
cord-311730-189vax2m	185	16	implemented	implement	VBN
cord-311730-189vax2m	185	17	-	-	:
cord-311730-189vax2m	185	18	Funders	funder	NNS
cord-311730-189vax2m	185	19	reiterated	reiterate	VBD
cord-311730-189vax2m	185	20	their	-PRON-	PRP$
cord-311730-189vax2m	185	21	current	current	JJ
cord-311730-189vax2m	185	22	financial	financial	JJ
cord-311730-189vax2m	185	23	commitments	commitment	NNS
cord-311730-189vax2m	185	24	to	to	IN
cord-311730-189vax2m	185	25	tackling	tackle	VBG
cord-311730-189vax2m	185	26	this	this	DT
cord-311730-189vax2m	185	27	outbreak	outbreak	NN
cord-311730-189vax2m	185	28	and	and	CC
cord-311730-189vax2m	185	29	agreed	agree	VBD
cord-311730-189vax2m	185	30	that	that	IN
cord-311730-189vax2m	185	31	the	the	DT
cord-311730-189vax2m	185	32	priorities	priority	NNS
cord-311730-189vax2m	185	33	agreed	agree	VBD
cord-311730-189vax2m	185	34	at	at	IN
cord-311730-189vax2m	185	35	the	the	DT
cord-311730-189vax2m	185	36	Forum	Forum	NNP
cord-311730-189vax2m	185	37	would	would	MD
cord-311730-189vax2m	185	38	help	help	VB
cord-311730-189vax2m	185	39	to	to	TO
cord-311730-189vax2m	185	40	coordinate	coordinate	VB
cord-311730-189vax2m	185	41	existing	exist	VBG
cord-311730-189vax2m	185	42	investments	investment	NNS
cord-311730-189vax2m	185	43	and	and	CC
cord-311730-189vax2m	185	44	inform	inform	VB
cord-311730-189vax2m	185	45	mobilization	mobilization	NN
cord-311730-189vax2m	185	46	of	of	IN
cord-311730-189vax2m	185	47	additional	additional	JJ
cord-311730-189vax2m	185	48	resources	resource	NNS
cord-311730-189vax2m	185	49	in	in	IN
cord-311730-189vax2m	185	50	the	the	DT
cord-311730-189vax2m	185	51	coming	come	VBG
cord-311730-189vax2m	185	52	days	day	NNS
cord-311730-189vax2m	185	53	,	,	,
cord-311730-189vax2m	185	54	weeks	week	NNS
cord-311730-189vax2m	185	55	and	and	CC
cord-311730-189vax2m	185	56	months	month	NNS
cord-311730-189vax2m	185	57	8	8	CD
cord-311730-189vax2m	185	58	.	.	.
cord-311730-189vax2m	186	1	Broadly	broadly	RB
cord-311730-189vax2m	186	2	and	and	CC
cord-311730-189vax2m	186	3	rapidly	rapidly	RB
cord-311730-189vax2m	186	4	share	share	VBP
cord-311730-189vax2m	186	5	virus	virus	NN
cord-311730-189vax2m	186	6	materials	material	NNS
cord-311730-189vax2m	186	7	,	,	,
cord-311730-189vax2m	186	8	clinical	clinical	JJ
cord-311730-189vax2m	186	9	samples	sample	NNS
cord-311730-189vax2m	186	10	and	and	CC
cord-311730-189vax2m	186	11	data	datum	NNS
cord-311730-189vax2m	186	12	for	for	IN
cord-311730-189vax2m	186	13	immediate	immediate	JJ
cord-311730-189vax2m	186	14	public	public	JJ
cord-311730-189vax2m	186	15	health	health	NN
cord-311730-189vax2m	186	16	purposes	purpose	NNS
cord-311730-189vax2m	187	1	-It	-It	:
cord-311730-189vax2m	187	2	was	be	VBD
cord-311730-189vax2m	187	3	agreed	agree	VBN
cord-311730-189vax2m	187	4	that	that	IN
cord-311730-189vax2m	187	5	virus	virus	NN
cord-311730-189vax2m	187	6	materials	material	NNS
cord-311730-189vax2m	187	7	,	,	,
cord-311730-189vax2m	187	8	clinical	clinical	JJ
cord-311730-189vax2m	187	9	samples	sample	NNS
cord-311730-189vax2m	187	10	and	and	CC
cord-311730-189vax2m	187	11	associated	associated	JJ
cord-311730-189vax2m	187	12	data	datum	NNS
cord-311730-189vax2m	187	13	should	should	MD
cord-311730-189vax2m	187	14	be	be	VB
cord-311730-189vax2m	187	15	rapidly	rapidly	RB
cord-311730-189vax2m	187	16	shared	share	VBN
cord-311730-189vax2m	187	17	for	for	IN
cord-311730-189vax2m	187	18	immediate	immediate	JJ
cord-311730-189vax2m	187	19	public	public	JJ
cord-311730-189vax2m	187	20	health	health	NN
cord-311730-189vax2m	187	21	purposes	purpose	NNS
cord-311730-189vax2m	187	22	and	and	CC
cord-311730-189vax2m	187	23	that	that	IN
cord-311730-189vax2m	187	24	fair	fair	JJ
cord-311730-189vax2m	187	25	and	and	CC
cord-311730-189vax2m	187	26	equitable	equitable	JJ
cord-311730-189vax2m	187	27	access	access	NN
cord-311730-189vax2m	187	28	to	to	IN
cord-311730-189vax2m	187	29	any	any	DT
cord-311730-189vax2m	187	30	medical	medical	JJ
cord-311730-189vax2m	187	31	products	product	NNS
cord-311730-189vax2m	187	32	or	or	CC
cord-311730-189vax2m	187	33	innovations	innovation	NNS
cord-311730-189vax2m	187	34	that	that	WDT
cord-311730-189vax2m	187	35	are	be	VBP
cord-311730-189vax2m	187	36	developed	develop	VBN
cord-311730-189vax2m	187	37	using	use	VBG
cord-311730-189vax2m	187	38	the	the	DT
cord-311730-189vax2m	187	39	materials	material	NNS
cord-311730-189vax2m	187	40	must	must	MD
cord-311730-189vax2m	187	41	be	be	VB
cord-311730-189vax2m	187	42	part	part	NN
cord-311730-189vax2m	187	43	of	of	IN
cord-311730-189vax2m	187	44	such	such	JJ
cord-311730-189vax2m	187	45	sharing	sharing	NN
cord-311730-189vax2m	187	46	The	the	DT
cord-311730-189vax2m	187	47	Covid-19	covid-19	JJ
cord-311730-189vax2m	187	48	pandemic	pandemic	NN
cord-311730-189vax2m	187	49	has	have	VBZ
cord-311730-189vax2m	187	50	touched	touch	VBN
cord-311730-189vax2m	187	51	everyone	everyone	NN
cord-311730-189vax2m	187	52	on	on	IN
cord-311730-189vax2m	187	53	Earth	Earth	NNP
cord-311730-189vax2m	187	54	in	in	IN
cord-311730-189vax2m	187	55	many	many	JJ
cord-311730-189vax2m	187	56	ways	way	NNS
cord-311730-189vax2m	187	57	.	.	.
cord-311730-189vax2m	188	1	Its	-PRON-	PRP$
cord-311730-189vax2m	188	2	scope	scope	NN
cord-311730-189vax2m	188	3	and	and	CC
cord-311730-189vax2m	188	4	impact	impact	NN
cord-311730-189vax2m	188	5	on	on	IN
cord-311730-189vax2m	188	6	health	health	NN
cord-311730-189vax2m	188	7	,	,	,
cord-311730-189vax2m	188	8	well	well	RB
cord-311730-189vax2m	188	9	-	-	HYPH
cord-311730-189vax2m	188	10	being	be	VBG
cord-311730-189vax2m	188	11	,	,	,
cord-311730-189vax2m	188	12	economic	economic	JJ
cord-311730-189vax2m	188	13	stability	stability	NN
cord-311730-189vax2m	188	14	and	and	CC
cord-311730-189vax2m	188	15	daily	daily	JJ
cord-311730-189vax2m	188	16	life	life	NN
cord-311730-189vax2m	188	17	is	be	VBZ
cord-311730-189vax2m	188	18	tragic	tragic	JJ
cord-311730-189vax2m	188	19	,	,	,
cord-311730-189vax2m	188	20	heart	heart	NN
cord-311730-189vax2m	188	21	-	-	HYPH
cord-311730-189vax2m	188	22	breaking	break	VBG
cord-311730-189vax2m	188	23	and	and	CC
cord-311730-189vax2m	188	24	quite	quite	RB
cord-311730-189vax2m	188	25	personal	personal	JJ
cord-311730-189vax2m	188	26	.	.	.
cord-311730-189vax2m	189	1	Despite	despite	IN
cord-311730-189vax2m	189	2	an	an	DT
cord-311730-189vax2m	189	3	honest	honest	JJ
cord-311730-189vax2m	189	4	and	and	CC
cord-311730-189vax2m	189	5	natural	natural	JJ
cord-311730-189vax2m	189	6	human	human	JJ
cord-311730-189vax2m	189	7	response	response	NN
cord-311730-189vax2m	189	8	to	to	IN
cord-311730-189vax2m	189	9	a	a	DT
cord-311730-189vax2m	189	10	clear	clear	JJ
cord-311730-189vax2m	189	11	threat	threat	NN
cord-311730-189vax2m	189	12	,	,	,
cord-311730-189vax2m	189	13	this	this	DT
cord-311730-189vax2m	189	14	is	be	VBZ
cord-311730-189vax2m	189	15	not	not	RB
cord-311730-189vax2m	189	16	a	a	DT
cord-311730-189vax2m	189	17	time	time	NN
cord-311730-189vax2m	189	18	for	for	IN
cord-311730-189vax2m	189	19	reactions	reaction	NNS
cord-311730-189vax2m	189	20	;	;	:
cord-311730-189vax2m	189	21	this	this	DT
cord-311730-189vax2m	189	22	is	be	VBZ
cord-311730-189vax2m	189	23	not	not	RB
cord-311730-189vax2m	189	24	a	a	DT
cord-311730-189vax2m	189	25	time	time	NN
cord-311730-189vax2m	189	26	for	for	IN
cord-311730-189vax2m	189	27	assumptions	assumption	NNS
cord-311730-189vax2m	189	28	;	;	:
cord-311730-189vax2m	189	29	this	this	DT
cord-311730-189vax2m	189	30	is	be	VBZ
cord-311730-189vax2m	189	31	not	not	RB
cord-311730-189vax2m	189	32	a	a	DT
cord-311730-189vax2m	189	33	time	time	NN
cord-311730-189vax2m	189	34	for	for	IN
cord-311730-189vax2m	189	35	desperate	desperate	JJ
cord-311730-189vax2m	189	36	measures	measure	NNS
cord-311730-189vax2m	189	37	;	;	:
cord-311730-189vax2m	189	38	this	this	DT
cord-311730-189vax2m	189	39	is	be	VBZ
cord-311730-189vax2m	189	40	not	not	RB
cord-311730-189vax2m	189	41	a	a	DT
cord-311730-189vax2m	189	42	time	time	NN
cord-311730-189vax2m	189	43	for	for	IN
cord-311730-189vax2m	189	44	guessing	guess	VBG
cord-311730-189vax2m	189	45	what	what	WP
cord-311730-189vax2m	189	46	might	may	MD
cord-311730-189vax2m	189	47	be	be	VB
cord-311730-189vax2m	189	48	a	a	DT
cord-311730-189vax2m	189	49	safe	safe	JJ
cord-311730-189vax2m	189	50	and	and	CC
cord-311730-189vax2m	189	51	effective	effective	JJ
cord-311730-189vax2m	189	52	treatment	treatment	NN
cord-311730-189vax2m	189	53	.	.	.
cord-311730-189vax2m	190	1	This	this	DT
cord-311730-189vax2m	190	2	is	be	VBZ
cord-311730-189vax2m	190	3	a	a	DT
cord-311730-189vax2m	190	4	time	time	NN
cord-311730-189vax2m	190	5	for	for	IN
cord-311730-189vax2m	190	6	facts	fact	NNS
cord-311730-189vax2m	190	7	,	,	,
cord-311730-189vax2m	190	8	measured	measure	VBN
cord-311730-189vax2m	190	9	steps	step	NNS
cord-311730-189vax2m	190	10	,	,	,
cord-311730-189vax2m	190	11	thoughtful	thoughtful	JJ
cord-311730-189vax2m	190	12	responses	response	NNS
cord-311730-189vax2m	190	13	and	and	CC
cord-311730-189vax2m	190	14	collaborations	collaboration	NNS
cord-311730-189vax2m	190	15	without	without	IN
cord-311730-189vax2m	190	16	borders	border	NNS
cord-311730-189vax2m	190	17	.	.	.
cord-311730-189vax2m	191	1	This	this	DT
cord-311730-189vax2m	191	2	is	be	VBZ
cord-311730-189vax2m	191	3	without	without	IN
cord-311730-189vax2m	191	4	question	question	NN
cord-311730-189vax2m	191	5	a	a	DT
cord-311730-189vax2m	191	6	time	time	NN
cord-311730-189vax2m	191	7	to	to	TO
cord-311730-189vax2m	191	8	follow	follow	VB
cord-311730-189vax2m	191	9	the	the	DT
cord-311730-189vax2m	191	10	scientific	scientific	JJ
cord-311730-189vax2m	191	11	evidence	evidence	NN
cord-311730-189vax2m	191	12	.	.	.
cord-311730-189vax2m	192	1	Escaping	escape	VBG
cord-311730-189vax2m	192	2	Pandora	Pandora	NNP
cord-311730-189vax2m	192	3	's	's	POS
cord-311730-189vax2m	192	4	box	box	NN
cord-311730-189vax2m	192	5	-	-	:
cord-311730-189vax2m	192	6	another	another	DT
cord-311730-189vax2m	192	7	novel	novel	JJ
cord-311730-189vax2m	192	8	Coronavirus	Coronavirus	NNP
cord-311730-189vax2m	192	9	Characteristics	Characteristics	NNPS
cord-311730-189vax2m	192	10	of	of	IN
cord-311730-189vax2m	192	11	and	and	CC
cord-311730-189vax2m	192	12	important	important	JJ
cord-311730-189vax2m	192	13	lessons	lesson	NNS
cord-311730-189vax2m	192	14	from	from	IN
cord-311730-189vax2m	192	15	the	the	DT
cord-311730-189vax2m	192	16	Coronavirus	Coronavirus	NNP
cord-311730-189vax2m	192	17	disease	disease	NN
cord-311730-189vax2m	192	18	2019	2019	CD
cord-311730-189vax2m	192	19	(	(	-LRB-
cord-311730-189vax2m	192	20	COVID-19	COVID-19	NNP
cord-311730-189vax2m	192	21	)	)	-RRB-
cord-311730-189vax2m	192	22	outbreak	outbreak	NN
cord-311730-189vax2m	192	23	in	in	IN
cord-311730-189vax2m	192	24	China	China	NNP
cord-311730-189vax2m	192	25	:	:	:
cord-311730-189vax2m	192	26	summary	summary	NN
cord-311730-189vax2m	192	27	of	of	IN
cord-311730-189vax2m	192	28	a	a	DT
cord-311730-189vax2m	192	29	report	report	NN
cord-311730-189vax2m	192	30	of	of	IN
cord-311730-189vax2m	192	31	72314	72314	CD
cord-311730-189vax2m	192	32	cases	case	NNS
cord-311730-189vax2m	192	33	from	from	IN
cord-311730-189vax2m	192	34	the	the	DT
cord-311730-189vax2m	192	35	Chinese	Chinese	NNP
cord-311730-189vax2m	192	36	Center	Center	NNP
cord-311730-189vax2m	192	37	for	for	IN
cord-311730-189vax2m	192	38	disease	disease	NNP
cord-311730-189vax2m	192	39	control	control	NN
cord-311730-189vax2m	192	40	and	and	CC
cord-311730-189vax2m	192	41	prevention	prevention	NN
cord-311730-189vax2m	192	42	Race	race	NN
cord-311730-189vax2m	192	43	to	to	TO
cord-311730-189vax2m	192	44	find	find	VB
cord-311730-189vax2m	192	45	COVID-19	covid-19	JJ
cord-311730-189vax2m	192	46	treatments	treatment	NNS
cord-311730-189vax2m	192	47	accelerates	accelerate	VBZ
cord-311730-189vax2m	192	48	Potential	Potential	NNP
cord-311730-189vax2m	192	49	of	of	IN
cord-311730-189vax2m	192	50	chloroquine	chloroquine	NNP
cord-311730-189vax2m	192	51	and	and	CC
cord-311730-189vax2m	192	52	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	192	53	to	to	TO
cord-311730-189vax2m	192	54	treat	treat	VB
cord-311730-189vax2m	193	1	COVID-19	COVID-19	NNP
cord-311730-189vax2m	193	2	causes	cause	VBZ
cord-311730-189vax2m	193	3	fears	fear	NNS
cord-311730-189vax2m	193	4	of	of	IN
cord-311730-189vax2m	193	5	shortages	shortage	NNS
cord-311730-189vax2m	193	6	among	among	IN
cord-311730-189vax2m	193	7	people	people	NNS
cord-311730-189vax2m	193	8	with	with	IN
cord-311730-189vax2m	193	9	systemic	systemic	JJ
cord-311730-189vax2m	193	10	lupus	lupus	NN
cord-311730-189vax2m	193	11	erythematosus	erythematosus	NN
cord-311730-189vax2m	193	12	Antimalarial	Antimalarial	NNP
cord-311730-189vax2m	193	13	drug	drug	NN
cord-311730-189vax2m	193	14	resistance	resistance	NN
cord-311730-189vax2m	193	15	in	in	IN
cord-311730-189vax2m	193	16	Africa	Africa	NNP
cord-311730-189vax2m	193	17	:	:	:
cord-311730-189vax2m	193	18	strategies	strategy	NNS
cord-311730-189vax2m	193	19	for	for	IN
cord-311730-189vax2m	193	20	monitoring	monitoring	NN
cord-311730-189vax2m	193	21	and	and	CC
cord-311730-189vax2m	193	22	deterrence	deterrence	NN
cord-311730-189vax2m	193	23	Effects	effect	NNS
cord-311730-189vax2m	193	24	of	of	IN
cord-311730-189vax2m	193	25	chloroquine	chloroquine	NN
cord-311730-189vax2m	193	26	on	on	IN
cord-311730-189vax2m	193	27	viral	viral	JJ
cord-311730-189vax2m	193	28	infections	infection	NNS
cord-311730-189vax2m	193	29	:	:	:
cord-311730-189vax2m	193	30	an	an	DT
cord-311730-189vax2m	193	31	old	old	JJ
cord-311730-189vax2m	193	32	drug	drug	NN
cord-311730-189vax2m	193	33	against	against	IN
cord-311730-189vax2m	193	34	today	today	NN
cord-311730-189vax2m	193	35	's	's	POS
cord-311730-189vax2m	193	36	diseases	disease	NNS
cord-311730-189vax2m	194	1	Chloroquine	Chloroquine	NNP
cord-311730-189vax2m	194	2	reduces	reduce	VBZ
cord-311730-189vax2m	194	3	hypercoagulability	hypercoagulability	NN
cord-311730-189vax2m	194	4	in	in	IN
cord-311730-189vax2m	194	5	pancreatic	pancreatic	JJ
cord-311730-189vax2m	194	6	cancer	cancer	NN
cord-311730-189vax2m	194	7	through	through	IN
cord-311730-189vax2m	194	8	inhibition	inhibition	NN
cord-311730-189vax2m	194	9	of	of	IN
cord-311730-189vax2m	194	10	neutrophil	neutrophil	NN
cord-311730-189vax2m	194	11	extracellular	extracellular	JJ
cord-311730-189vax2m	194	12	traps	trap	NNS
cord-311730-189vax2m	195	1	Chloroquine	Chloroquine	NNP
cord-311730-189vax2m	195	2	differentially	differentially	RB
cord-311730-189vax2m	195	3	modulates	modulate	VBZ
cord-311730-189vax2m	195	4	coronary	coronary	JJ
cord-311730-189vax2m	195	5	vasodilation	vasodilation	NN
cord-311730-189vax2m	195	6	in	in	IN
cord-311730-189vax2m	195	7	control	control	NN
cord-311730-189vax2m	195	8	and	and	CC
cord-311730-189vax2m	195	9	diabetic	diabetic	JJ
cord-311730-189vax2m	195	10	mice	mouse	NNS
cord-311730-189vax2m	196	1	Chloroquine	Chloroquine	NNP
cord-311730-189vax2m	196	2	improves	improve	VBZ
cord-311730-189vax2m	196	3	left	leave	VBN
cord-311730-189vax2m	196	4	ventricle	ventricle	NN
cord-311730-189vax2m	196	5	diastolic	diastolic	JJ
cord-311730-189vax2m	196	6	function	function	NN
cord-311730-189vax2m	196	7	in	in	IN
cord-311730-189vax2m	196	8	streptozotocin	streptozotocin	NN
cord-311730-189vax2m	196	9	-	-	HYPH
cord-311730-189vax2m	196	10	induced	induce	VBN
cord-311730-189vax2m	196	11	diabetic	diabetic	JJ
cord-311730-189vax2m	196	12	mice	mice	NN
cord-311730-189vax2m	196	13	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-311730-189vax2m	196	14	:	:	:
cord-311730-189vax2m	196	15	from	from	IN
cord-311730-189vax2m	196	16	malaria	malaria	NN
cord-311730-189vax2m	196	17	to	to	IN
cord-311730-189vax2m	196	18	autoimmunity	autoimmunity	NN
cord-311730-189vax2m	196	19	Revisiting	revisit	VBG
cord-311730-189vax2m	196	20	the	the	DT
cord-311730-189vax2m	196	21	cardiotoxic	cardiotoxic	JJ
cord-311730-189vax2m	196	22	effect	effect	NN
cord-311730-189vax2m	196	23	of	of	IN
cord-311730-189vax2m	196	24	chloroquine	chloroquine	NN
cord-311730-189vax2m	197	1	In	in	IN
cord-311730-189vax2m	197	2	vitro	vitro	FW
cord-311730-189vax2m	197	3	inhibition	inhibition	NN
cord-311730-189vax2m	197	4	of	of	IN
cord-311730-189vax2m	197	5	severe	severe	JJ
cord-311730-189vax2m	197	6	acute	acute	JJ
cord-311730-189vax2m	197	7	respiratory	respiratory	JJ
cord-311730-189vax2m	197	8	syndrome	syndrome	NN
cord-311730-189vax2m	197	9	coronavirus	coronavirus	NN
cord-311730-189vax2m	197	10	by	by	IN
cord-311730-189vax2m	197	11	chloroquine	chloroquine	NN
cord-311730-189vax2m	197	12	Antiviral	antiviral	JJ
cord-311730-189vax2m	197	13	activity	activity	NN
cord-311730-189vax2m	197	14	of	of	IN
cord-311730-189vax2m	197	15	chloroquine	chloroquine	NN
cord-311730-189vax2m	197	16	against	against	IN
cord-311730-189vax2m	197	17	human	human	JJ
cord-311730-189vax2m	197	18	Coronavirus	Coronavirus	NNP
cord-311730-189vax2m	197	19	OC43	OC43	NNP
cord-311730-189vax2m	197	20	infection	infection	NN
cord-311730-189vax2m	197	21	in	in	IN
cord-311730-189vax2m	197	22	newborn	newborn	JJ
cord-311730-189vax2m	197	23	mice	mouse	NNS
cord-311730-189vax2m	197	24	Remdesivir	Remdesivir	NNP
cord-311730-189vax2m	197	25	and	and	CC
cord-311730-189vax2m	197	26	chloroquine	chloroquine	NN
cord-311730-189vax2m	197	27	effectively	effectively	RB
cord-311730-189vax2m	197	28	inhibit	inhibit	VBP
cord-311730-189vax2m	197	29	the	the	DT
cord-311730-189vax2m	197	30	recently	recently	RB
cord-311730-189vax2m	197	31	emerged	emerge	VBN
cord-311730-189vax2m	197	32	novel	novel	JJ
cord-311730-189vax2m	197	33	coronavirus	coronavirus	NN
cord-311730-189vax2m	197	34	(	(	-LRB-
cord-311730-189vax2m	197	35	2019-nCoV	2019-ncov	CD
cord-311730-189vax2m	197	36	)	)	-RRB-
cord-311730-189vax2m	197	37	in	in	IN
cord-311730-189vax2m	197	38	vitro	vitro	FW
cord-311730-189vax2m	197	39	Treating	treat	VBG
cord-311730-189vax2m	197	40	COVID-19	covid-19	CD
cord-311730-189vax2m	197	41	with	with	IN
cord-311730-189vax2m	197	42	chloroquine	chloroquine	NN
cord-311730-189vax2m	197	43	Chloroquine	Chloroquine	NNP
cord-311730-189vax2m	197	44	analogues	analogue	NNS
cord-311730-189vax2m	197	45	in	in	IN
cord-311730-189vax2m	197	46	drug	drug	NN
cord-311730-189vax2m	197	47	discovery	discovery	NN
cord-311730-189vax2m	197	48	:	:	:
cord-311730-189vax2m	197	49	new	new	JJ
cord-311730-189vax2m	197	50	directions	direction	NNS
cord-311730-189vax2m	197	51	of	of	IN
cord-311730-189vax2m	197	52	uses	use	NNS
cord-311730-189vax2m	197	53	,	,	,
cord-311730-189vax2m	197	54	mechanisms	mechanism	NNS
cord-311730-189vax2m	197	55	of	of	IN
cord-311730-189vax2m	197	56	actions	action	NNS
cord-311730-189vax2m	197	57	and	and	CC
cord-311730-189vax2m	197	58	toxic	toxic	JJ
cord-311730-189vax2m	197	59	manifestations	manifestation	NNS
cord-311730-189vax2m	197	60	from	from	IN
cord-311730-189vax2m	197	61	malaria	malaria	NN
cord-311730-189vax2m	197	62	to	to	IN
cord-311730-189vax2m	197	63	multifarious	multifarious	JJ
cord-311730-189vax2m	197	64	diseases	disease	NNS
cord-311730-189vax2m	197	65	Current	current	JJ
cord-311730-189vax2m	197	66	and	and	CC
cord-311730-189vax2m	197	67	future	future	JJ
cord-311730-189vax2m	197	68	use	use	NN
cord-311730-189vax2m	197	69	of	of	IN
cord-311730-189vax2m	197	70	chloroquine	chloroquine	NN
cord-311730-189vax2m	197	71	and	and	CC
cord-311730-189vax2m	197	72	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	197	73	in	in	IN
cord-311730-189vax2m	197	74	infectious	infectious	JJ
cord-311730-189vax2m	197	75	,	,	,
cord-311730-189vax2m	197	76	immune	immune	JJ
cord-311730-189vax2m	197	77	,	,	,
cord-311730-189vax2m	197	78	neoplastic	neoplastic	JJ
cord-311730-189vax2m	197	79	,	,	,
cord-311730-189vax2m	197	80	and	and	CC
cord-311730-189vax2m	197	81	neurological	neurological	JJ
cord-311730-189vax2m	197	82	diseases	disease	NNS
cord-311730-189vax2m	197	83	:	:	:
cord-311730-189vax2m	198	1	a	a	DT
cord-311730-189vax2m	198	2	mini	mini	JJ
cord-311730-189vax2m	198	3	-	-	NN
cord-311730-189vax2m	198	4	review	review	NN
cord-311730-189vax2m	198	5	Fluorescence	Fluorescence	NNP
cord-311730-189vax2m	198	6	probe	probe	NN
cord-311730-189vax2m	198	7	measurement	measurement	NN
cord-311730-189vax2m	198	8	of	of	IN
cord-311730-189vax2m	198	9	the	the	DT
cord-311730-189vax2m	198	10	intralysosomal	intralysosomal	NNP
cord-311730-189vax2m	198	11	pH	pH	NNP
cord-311730-189vax2m	199	1	in	in	IN
cord-311730-189vax2m	199	2	living	live	VBG
cord-311730-189vax2m	199	3	cells	cell	NNS
cord-311730-189vax2m	199	4	and	and	CC
cord-311730-189vax2m	199	5	the	the	DT
cord-311730-189vax2m	199	6	perturbation	perturbation	NN
cord-311730-189vax2m	199	7	of	of	IN
cord-311730-189vax2m	199	8	pH	ph	NN
cord-311730-189vax2m	199	9	by	by	IN
cord-311730-189vax2m	199	10	various	various	JJ
cord-311730-189vax2m	199	11	agents	agent	NNS
cord-311730-189vax2m	199	12	Selective	selective	JJ
cord-311730-189vax2m	199	13	regulation	regulation	NN
cord-311730-189vax2m	199	14	of	of	IN
cord-311730-189vax2m	199	15	cytokine	cytokine	JJ
cord-311730-189vax2m	199	16	secretion	secretion	NN
cord-311730-189vax2m	199	17	by	by	IN
cord-311730-189vax2m	199	18	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	199	19	:	:	:
cord-311730-189vax2m	199	20	inhibition	inhibition	NN
cord-311730-189vax2m	199	21	of	of	IN
cord-311730-189vax2m	199	22	interleukin	interleukin	NN
cord-311730-189vax2m	199	23	1	1	CD
cord-311730-189vax2m	199	24	alpha	alpha	NN
cord-311730-189vax2m	199	25	(	(	-LRB-
cord-311730-189vax2m	199	26	IL-1-alpha	IL-1-alpha	''
cord-311730-189vax2m	199	27	)	)	-RRB-
cord-311730-189vax2m	199	28	and	and	CC
cord-311730-189vax2m	199	29	IL-6	IL-6	NNP
cord-311730-189vax2m	199	30	in	in	IN
cord-311730-189vax2m	199	31	human	human	JJ
cord-311730-189vax2m	199	32	monocytes	monocyte	NNS
cord-311730-189vax2m	199	33	and	and	CC
cord-311730-189vax2m	199	34	T	t	NN
cord-311730-189vax2m	199	35	cells	cell	NNS
cord-311730-189vax2m	200	1	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-311730-189vax2m	200	2	inhibits	inhibit	VBZ
cord-311730-189vax2m	200	3	calcium	calcium	NN
cord-311730-189vax2m	200	4	signals	signal	NNS
cord-311730-189vax2m	200	5	in	in	IN
cord-311730-189vax2m	200	6	T	T	NNP
cord-311730-189vax2m	200	7	cells	cell	NNS
cord-311730-189vax2m	200	8	:	:	:
cord-311730-189vax2m	201	1	a	a	DT
cord-311730-189vax2m	201	2	new	new	JJ
cord-311730-189vax2m	201	3	mechanism	mechanism	NN
cord-311730-189vax2m	201	4	to	to	TO
cord-311730-189vax2m	201	5	explain	explain	VB
cord-311730-189vax2m	201	6	its	-PRON-	PRP$
cord-311730-189vax2m	201	7	immunomodulatory	immunomodulatory	JJ
cord-311730-189vax2m	201	8	properties	property	NNS
cord-311730-189vax2m	201	9	Structural	structural	JJ
cord-311730-189vax2m	201	10	and	and	CC
cord-311730-189vax2m	201	11	molecular	molecular	JJ
cord-311730-189vax2m	201	12	modeling	modeling	NN
cord-311730-189vax2m	201	13	studies	study	NNS
cord-311730-189vax2m	201	14	reveal	reveal	VBP
cord-311730-189vax2m	201	15	a	a	DT
cord-311730-189vax2m	201	16	new	new	JJ
cord-311730-189vax2m	201	17	mechanism	mechanism	NN
cord-311730-189vax2m	201	18	of	of	IN
cord-311730-189vax2m	201	19	action	action	NN
cord-311730-189vax2m	201	20	of	of	IN
cord-311730-189vax2m	201	21	chloroquine	chloroquine	NNP
cord-311730-189vax2m	201	22	and	and	CC
cord-311730-189vax2m	201	23	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	201	24	against	against	IN
cord-311730-189vax2m	201	25	SARS	SARS	NNP
cord-311730-189vax2m	201	26	-	-	HYPH
cord-311730-189vax2m	201	27	CoV-2	CoV-2	NNP
cord-311730-189vax2m	201	28	infection	infection	NN
cord-311730-189vax2m	201	29	Treatment	treatment	NN
cord-311730-189vax2m	201	30	with	with	IN
cord-311730-189vax2m	201	31	tumor	tumor	NN
cord-311730-189vax2m	201	32	necrosis	necrosis	NN
cord-311730-189vax2m	201	33	factor	factor	NN
cord-311730-189vax2m	201	34	blockers	blocker	NNS
cord-311730-189vax2m	201	35	is	be	VBZ
cord-311730-189vax2m	201	36	associated	associate	VBN
cord-311730-189vax2m	201	37	with	with	IN
cord-311730-189vax2m	201	38	a	a	DT
cord-311730-189vax2m	201	39	lower	low	JJR
cord-311730-189vax2m	201	40	incidence	incidence	NN
cord-311730-189vax2m	201	41	of	of	IN
cord-311730-189vax2m	201	42	first	first	JJ
cord-311730-189vax2m	201	43	cardiovascular	cardiovascular	JJ
cord-311730-189vax2m	201	44	events	event	NNS
cord-311730-189vax2m	201	45	in	in	IN
cord-311730-189vax2m	201	46	patients	patient	NNS
cord-311730-189vax2m	201	47	with	with	IN
cord-311730-189vax2m	201	48	rheumatoid	rheumatoid	NN
cord-311730-189vax2m	201	49	arthritis	arthritis	NN
cord-311730-189vax2m	201	50	Inflammation	inflammation	NN
cord-311730-189vax2m	201	51	and	and	CC
cord-311730-189vax2m	201	52	coronary	coronary	JJ
cord-311730-189vax2m	201	53	artery	artery	NN
cord-311730-189vax2m	201	54	disease	disease	NN
cord-311730-189vax2m	201	55	:	:	:
cord-311730-189vax2m	201	56	from	from	IN
cord-311730-189vax2m	201	57	pathophysiology	pathophysiology	NN
cord-311730-189vax2m	201	58	to	to	IN
cord-311730-189vax2m	201	59	Canakinumab	Canakinumab	NNP
cord-311730-189vax2m	201	60	anti	anti	JJ
cord-311730-189vax2m	201	61	-	-	JJ
cord-311730-189vax2m	201	62	inflammatory	inflammatory	JJ
cord-311730-189vax2m	201	63	thrombosis	thrombosis	NN
cord-311730-189vax2m	201	64	outcomes	outcome	NNS
cord-311730-189vax2m	201	65	study	study	NN
cord-311730-189vax2m	201	66	(	(	-LRB-
cord-311730-189vax2m	201	67	CANTOS	CANTOS	NNP
cord-311730-189vax2m	201	68	)	)	-RRB-
cord-311730-189vax2m	202	1	Metalloproteinases	metalloproteinase	NNS
cord-311730-189vax2m	202	2	promote	promote	VBP
cord-311730-189vax2m	202	3	plaque	plaque	NN
cord-311730-189vax2m	202	4	rupture	rupture	NN
cord-311730-189vax2m	202	5	and	and	CC
cord-311730-189vax2m	202	6	myocardial	myocardial	JJ
cord-311730-189vax2m	202	7	infarction	infarction	NN
cord-311730-189vax2m	202	8	:	:	:
cord-311730-189vax2m	202	9	a	a	DT
cord-311730-189vax2m	202	10	persuasive	persuasive	JJ
cord-311730-189vax2m	202	11	concept	concept	NN
cord-311730-189vax2m	202	12	waiting	wait	VBG
cord-311730-189vax2m	202	13	for	for	IN
cord-311730-189vax2m	202	14	clinical	clinical	JJ
cord-311730-189vax2m	202	15	translation	translation	NN
cord-311730-189vax2m	202	16	Cholesterol	cholesterol	NN
cord-311730-189vax2m	202	17	-	-	HYPH
cord-311730-189vax2m	202	18	lowering	lower	VBG
cord-311730-189vax2m	202	19	effect	effect	NN
cord-311730-189vax2m	202	20	of	of	IN
cord-311730-189vax2m	202	21	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	202	22	in	in	IN
cord-311730-189vax2m	202	23	patients	patient	NNS
cord-311730-189vax2m	202	24	with	with	IN
cord-311730-189vax2m	202	25	rheumatic	rheumatic	JJ
cord-311730-189vax2m	202	26	disease	disease	NN
cord-311730-189vax2m	202	27	:	:	:
cord-311730-189vax2m	202	28	reversal	reversal	NN
cord-311730-189vax2m	202	29	of	of	IN
cord-311730-189vax2m	202	30	deleterious	deleterious	JJ
cord-311730-189vax2m	202	31	effects	effect	NNS
cord-311730-189vax2m	202	32	of	of	IN
cord-311730-189vax2m	202	33	steroids	steroid	NNS
cord-311730-189vax2m	202	34	on	on	IN
cord-311730-189vax2m	202	35	lipids	lipid	NNS
cord-311730-189vax2m	202	36	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-311730-189vax2m	202	37	's	's	POS
cord-311730-189vax2m	202	38	efficacy	efficacy	NN
cord-311730-189vax2m	202	39	as	as	IN
cord-311730-189vax2m	202	40	an	an	DT
cord-311730-189vax2m	202	41	antiplatelet	antiplatelet	JJ
cord-311730-189vax2m	202	42	agent	agent	NN
cord-311730-189vax2m	202	43	study	study	NN
cord-311730-189vax2m	202	44	in	in	IN
cord-311730-189vax2m	202	45	healthy	healthy	JJ
cord-311730-189vax2m	202	46	volunteers	volunteer	NNS
cord-311730-189vax2m	202	47	:	:	:
cord-311730-189vax2m	202	48	a	a	DT
cord-311730-189vax2m	202	49	proof	proof	NN
cord-311730-189vax2m	202	50	of	of	IN
cord-311730-189vax2m	202	51	concept	concept	NN
cord-311730-189vax2m	202	52	study	study	NN
cord-311730-189vax2m	202	53	The	the	DT
cord-311730-189vax2m	202	54	protective	protective	JJ
cord-311730-189vax2m	202	55	effect	effect	NN
cord-311730-189vax2m	202	56	of	of	IN
cord-311730-189vax2m	202	57	antimalarial	antimalarial	JJ
cord-311730-189vax2m	202	58	drugs	drug	NNS
cord-311730-189vax2m	202	59	on	on	IN
cord-311730-189vax2m	202	60	thrombovascular	thrombovascular	NNP
cord-311730-189vax2m	202	61	events	event	NNS
cord-311730-189vax2m	202	62	in	in	IN
cord-311730-189vax2m	202	63	systemic	systemic	JJ
cord-311730-189vax2m	202	64	lupus	lupus	NN
cord-311730-189vax2m	202	65	erythematosus	erythematosu	VBG
cord-311730-189vax2m	202	66	Cardiac	cardiac	JJ
cord-311730-189vax2m	202	67	complications	complication	NNS
cord-311730-189vax2m	202	68	attributed	attribute	VBN
cord-311730-189vax2m	202	69	to	to	IN
cord-311730-189vax2m	202	70	chloroquine	chloroquine	NN
cord-311730-189vax2m	202	71	and	and	CC
cord-311730-189vax2m	202	72	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	202	73	:	:	:
cord-311730-189vax2m	202	74	a	a	DT
cord-311730-189vax2m	202	75	systematic	systematic	JJ
cord-311730-189vax2m	202	76	review	review	NN
cord-311730-189vax2m	202	77	of	of	IN
cord-311730-189vax2m	202	78	the	the	DT
cord-311730-189vax2m	202	79	literature	literature	NN
cord-311730-189vax2m	203	1	In	in	IN
cord-311730-189vax2m	203	2	vitro	vitro	FW
cord-311730-189vax2m	203	3	antiviral	antiviral	JJ
cord-311730-189vax2m	203	4	activity	activity	NN
cord-311730-189vax2m	203	5	and	and	CC
cord-311730-189vax2m	203	6	projection	projection	NN
cord-311730-189vax2m	203	7	of	of	IN
cord-311730-189vax2m	203	8	optimized	optimize	VBN
cord-311730-189vax2m	203	9	dosing	dosing	NN
cord-311730-189vax2m	203	10	design	design	NN
cord-311730-189vax2m	203	11	of	of	IN
cord-311730-189vax2m	203	12	hydroxychloroquine	hydroxychloroquine	NN
cord-311730-189vax2m	203	13	for	for	IN
cord-311730-189vax2m	203	14	the	the	DT
cord-311730-189vax2m	203	15	treatment	treatment	NN
cord-311730-189vax2m	203	16	of	of	IN
cord-311730-189vax2m	203	17	severe	severe	JJ
cord-311730-189vax2m	203	18	acute	acute	JJ
cord-311730-189vax2m	203	19	respiratory	respiratory	JJ
cord-311730-189vax2m	203	20	syndrome	syndrome	NN
cord-311730-189vax2m	203	21	Coronavirus	Coronavirus	NNP
cord-311730-189vax2m	203	22	2	2	CD
cord-311730-189vax2m	204	1	(	(	-LRB-
cord-311730-189vax2m	204	2	SARS	SARS	NNP
cord-311730-189vax2m	204	3	-	-	HYPH
cord-311730-189vax2m	204	4	CoV-2	CoV-2	NNP
cord-311730-189vax2m	204	5	)	)	-RRB-
cord-311730-189vax2m	204	6	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-311730-189vax2m	204	7	,	,	,
cord-311730-189vax2m	204	8	a	a	DT
cord-311730-189vax2m	204	9	less	less	RBR
cord-311730-189vax2m	204	10	toxic	toxic	JJ
cord-311730-189vax2m	204	11	derivative	derivative	NN
cord-311730-189vax2m	204	12	of	of	IN
cord-311730-189vax2m	204	13	chloroquine	chloroquine	NN
cord-311730-189vax2m	204	14	,	,	,
cord-311730-189vax2m	204	15	is	be	VBZ
cord-311730-189vax2m	204	16	effective	effective	JJ
cord-311730-189vax2m	204	17	in	in	IN
cord-311730-189vax2m	204	18	inhibiting	inhibit	VBG
cord-311730-189vax2m	204	19	SARS	SARS	NNP
cord-311730-189vax2m	204	20	-	-	HYPH
cord-311730-189vax2m	204	21	CoV-2	CoV-2	NNP
cord-311730-189vax2m	204	22	infection	infection	NN
cord-311730-189vax2m	204	23	in	in	IN
cord-311730-189vax2m	204	24	vitro	vitro	FW
cord-311730-189vax2m	204	25	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-311730-189vax2m	204	26	and	and	CC
cord-311730-189vax2m	204	27	azithromycin	azithromycin	NNP
cord-311730-189vax2m	204	28	as	as	IN
cord-311730-189vax2m	204	29	a	a	DT
cord-311730-189vax2m	204	30	treatment	treatment	NN
cord-311730-189vax2m	204	31	of	of	IN
cord-311730-189vax2m	204	32	COVID-19	covid-19	NN
cord-311730-189vax2m	204	33	:	:	:
cord-311730-189vax2m	204	34	results	result	NNS
cord-311730-189vax2m	204	35	of	of	IN
cord-311730-189vax2m	204	36	an	an	DT
cord-311730-189vax2m	204	37	openlabel	openlabel	NN
cord-311730-189vax2m	204	38	non	non	JJ
cord-311730-189vax2m	204	39	-	-	JJ
cord-311730-189vax2m	204	40	randomized	randomized	JJ
cord-311730-189vax2m	204	41	clinical	clinical	JJ
cord-311730-189vax2m	204	42	trial	trial	NN
cord-311730-189vax2m	205	1	Credible-Meds.org	Credible-Meds.org	NNP
cord-311730-189vax2m	205	2	:	:	:
cord-311730-189vax2m	206	1	What	what	WP
cord-311730-189vax2m	206	2	does	do	VBZ
cord-311730-189vax2m	206	3	it	-PRON-	PRP
cord-311730-189vax2m	206	4	offer	offer	VB
cord-311730-189vax2m	206	5	?	?	.
cord-311730-189vax2m	207	1	Impact	impact	NN
cord-311730-189vax2m	207	2	of	of	IN
cord-311730-189vax2m	207	3	the	the	DT
cord-311730-189vax2m	207	4	FDA	FDA	NNP
cord-311730-189vax2m	207	5	Warning	Warning	NNP
cord-311730-189vax2m	207	6	for	for	IN
cord-311730-189vax2m	207	7	Azithromycin	Azithromycin	NNP
cord-311730-189vax2m	207	8	and	and	CC
cord-311730-189vax2m	207	9	Risk	risk	NN
cord-311730-189vax2m	207	10	for	for	IN
cord-311730-189vax2m	207	11	QT	QT	NNP
cord-311730-189vax2m	207	12	Prolongation	Prolongation	NNP
cord-311730-189vax2m	207	13	on	on	IN
cord-311730-189vax2m	207	14	Utilization	Utilization	NNP
cord-311730-189vax2m	207	15	at	at	IN
cord-311730-189vax2m	207	16	an	an	DT
cord-311730-189vax2m	207	17	Academic	Academic	NNP
cord-311730-189vax2m	207	18	Medical	Medical	NNP
cord-311730-189vax2m	207	19	Center	Center	NNP
cord-311730-189vax2m	207	20	How	how	WRB
cord-311730-189vax2m	207	21	to	to	TO
cord-311730-189vax2m	207	22	prescribe	prescribe	VB
cord-311730-189vax2m	207	23	drugs	drug	NNS
cord-311730-189vax2m	207	24	with	with	IN
cord-311730-189vax2m	207	25	an	an	DT
cord-311730-189vax2m	207	26	identified	identify	VBN
cord-311730-189vax2m	207	27	proarrhythmic	proarrhythmic	JJ
cord-311730-189vax2m	207	28	liability	liability	NN
cord-311730-189vax2m	207	29	Development	Development	NNP
cord-311730-189vax2m	207	30	of	of	IN
cord-311730-189vax2m	207	31	a	a	DT
cord-311730-189vax2m	207	32	risk	risk	NN
cord-311730-189vax2m	207	33	score	score	NN
cord-311730-189vax2m	207	34	for	for	IN
cord-311730-189vax2m	207	35	QTc	qtc	NN
cord-311730-189vax2m	207	36	-	-	HYPH
cord-311730-189vax2m	207	37	prolongation	prolongation	NN
cord-311730-189vax2m	207	38	:	:	:
cord-311730-189vax2m	207	39	the	the	DT
cord-311730-189vax2m	207	40	RISQ	RISQ	NNP
cord-311730-189vax2m	207	41	-	-	HYPH
cord-311730-189vax2m	207	42	PATH	path	NN
cord-311730-189vax2m	207	43	study	study	NN
cord-311730-189vax2m	207	44	Chloroquine	Chloroquine	NNP
cord-311730-189vax2m	207	45	diphosphate	diphosphate	JJ
cord-311730-189vax2m	207	46	in	in	IN
cord-311730-189vax2m	207	47	two	two	CD
cord-311730-189vax2m	207	48	different	different	JJ
cord-311730-189vax2m	207	49	dosages	dosage	NNS
cord-311730-189vax2m	207	50	as	as	IN
cord-311730-189vax2m	207	51	adjunctive	adjunctive	JJ
cord-311730-189vax2m	207	52	therapy	therapy	NN
cord-311730-189vax2m	207	53	of	of	IN
cord-311730-189vax2m	207	54	hospitalized	hospitalize	VBN
cord-311730-189vax2m	207	55	patients	patient	NNS
cord-311730-189vax2m	207	56	with	with	IN
cord-311730-189vax2m	207	57	severe	severe	JJ
cord-311730-189vax2m	207	58	respiratory	respiratory	JJ
cord-311730-189vax2m	207	59	syndrome	syndrome	NN
cord-311730-189vax2m	207	60	in	in	IN
cord-311730-189vax2m	207	61	the	the	DT
cord-311730-189vax2m	207	62	context	context	NN
cord-311730-189vax2m	207	63	of	of	IN
cord-311730-189vax2m	207	64	coronavirus	coronavirus	NN
cord-311730-189vax2m	207	65	(	(	-LRB-
cord-311730-189vax2m	207	66	SARS	SARS	NNP
cord-311730-189vax2m	207	67	-	-	HYPH
cord-311730-189vax2m	207	68	CoV-2	CoV-2	NNP
cord-311730-189vax2m	207	69	)	)	-RRB-
cord-311730-189vax2m	207	70	infection	infection	NN
cord-311730-189vax2m	207	71	:	:	:
cord-311730-189vax2m	208	1	Preliminary	preliminary	JJ
cord-311730-189vax2m	208	2	safety	safety	NN
cord-311730-189vax2m	208	3	results	result	NNS
cord-311730-189vax2m	208	4	of	of	IN
cord-311730-189vax2m	208	5	a	a	DT
cord-311730-189vax2m	208	6	randomized	randomized	JJ
cord-311730-189vax2m	208	7	,	,	,
cord-311730-189vax2m	208	8	double	double	JJ
cord-311730-189vax2m	208	9	-	-	HYPH
cord-311730-189vax2m	208	10	blinded	blinded	JJ
cord-311730-189vax2m	208	11	WHO	who	WP
cord-311730-189vax2m	209	1	R&D	R&D	NNP
cord-311730-189vax2m	209	2	Blueprint	Blueprint	NNP
cord-311730-189vax2m	209	3	:	:	:
cord-311730-189vax2m	209	4	a	a	DT
cord-311730-189vax2m	209	5	global	global	JJ
cord-311730-189vax2m	209	6	coordination	coordination	NN
cord-311730-189vax2m	209	7	mechanism	mechanism	NN
cord-311730-189vax2m	209	8	for	for	IN
cord-311730-189vax2m	209	9	R&D	r&d	NN
cord-311730-189vax2m	209	10	preparedness	preparedness	NN
cord-311730-189vax2m	209	11	Master	Master	NNP
cord-311730-189vax2m	209	12	protocols	protocol	NNS
cord-311730-189vax2m	209	13	to	to	TO
cord-311730-189vax2m	209	14	study	study	VB
cord-311730-189vax2m	209	15	multiple	multiple	JJ
cord-311730-189vax2m	209	16	therapies	therapy	NNS
cord-311730-189vax2m	209	17	,	,	,
cord-311730-189vax2m	209	18	multiple	multiple	JJ
cord-311730-189vax2m	209	19	diseases	disease	NNS
cord-311730-189vax2m	209	20	,	,	,
cord-311730-189vax2m	209	21	or	or	CC
cord-311730-189vax2m	209	22	both	both	DT