id sid tid token lemma pos cord-308293-8y2iaqnl 1 1 key key NN cord-308293-8y2iaqnl 1 2 : : : cord-308293-8y2iaqnl 2 1 cord-308293 cord-308293 NNP cord-308293-8y2iaqnl 2 2 - - HYPH cord-308293-8y2iaqnl 2 3 8y2iaqnl 8y2iaqnl CD cord-308293-8y2iaqnl 2 4 authors author NNS cord-308293-8y2iaqnl 2 5 : : : cord-308293-8y2iaqnl 2 6 Singh Singh NNP cord-308293-8y2iaqnl 2 7 , , , cord-308293-8y2iaqnl 2 8 Vijay Vijay NNP cord-308293-8y2iaqnl 2 9 P. P. NNP cord-308293-8y2iaqnl 2 10 ; ; : cord-308293-8y2iaqnl 2 11 El El NNP cord-308293-8y2iaqnl 2 12 - - HYPH cord-308293-8y2iaqnl 2 13 Kurdi Kurdi NNP cord-308293-8y2iaqnl 2 14 , , , cord-308293-8y2iaqnl 2 15 Bara Bara NNP cord-308293-8y2iaqnl 2 16 ; ; : cord-308293-8y2iaqnl 2 17 Rood Rood NNP cord-308293-8y2iaqnl 2 18 , , , cord-308293-8y2iaqnl 2 19 Christopher Christopher NNP cord-308293-8y2iaqnl 2 20 title title NN cord-308293-8y2iaqnl 2 21 : : : cord-308293-8y2iaqnl 3 1 What what WP cord-308293-8y2iaqnl 3 2 underlies underlie VBZ cord-308293-8y2iaqnl 3 3 the the DT cord-308293-8y2iaqnl 3 4 benefit benefit NN cord-308293-8y2iaqnl 3 5 of of IN cord-308293-8y2iaqnl 3 6 famotidine famotidine NN cord-308293-8y2iaqnl 3 7 formulations formulation NNS cord-308293-8y2iaqnl 3 8 used use VBN cord-308293-8y2iaqnl 3 9 during during IN cord-308293-8y2iaqnl 3 10 COVID-19 COVID-19 NNP cord-308293-8y2iaqnl 3 11 ? ? . cord-308293-8y2iaqnl 3 12 date date NN cord-308293-8y2iaqnl 3 13 : : : cord-308293-8y2iaqnl 3 14 2020 2020 CD cord-308293-8y2iaqnl 3 15 - - HYPH cord-308293-8y2iaqnl 3 16 08 08 CD cord-308293-8y2iaqnl 3 17 - - HYPH cord-308293-8y2iaqnl 3 18 07 07 CD cord-308293-8y2iaqnl 3 19 journal journal NN cord-308293-8y2iaqnl 3 20 : : : cord-308293-8y2iaqnl 4 1 Gastroenterology Gastroenterology NNP cord-308293-8y2iaqnl 4 2 DOI DOI NNP cord-308293-8y2iaqnl 4 3 : : : cord-308293-8y2iaqnl 4 4 10.1053 10.1053 CD cord-308293-8y2iaqnl 4 5 / / SYM cord-308293-8y2iaqnl 4 6 j.gastro.2020.07.051 j.gastro.2020.07.051 CD cord-308293-8y2iaqnl 4 7 sha sha NN cord-308293-8y2iaqnl 4 8 : : : cord-308293-8y2iaqnl 4 9 99601d300942a5f4d8d326f85284bd8e6c341f9d 99601d300942a5f4d8d326f85284bd8e6c341f9d CD cord-308293-8y2iaqnl 4 10 doc_id doc_id CD cord-308293-8y2iaqnl 4 11 : : : cord-308293-8y2iaqnl 4 12 308293 308293 CD cord-308293-8y2iaqnl 4 13 cord_uid cord_uid FW cord-308293-8y2iaqnl 4 14 : : : cord-308293-8y2iaqnl 5 1 8y2iaqnl 8y2iaqnl NNP cord-308293-8y2iaqnl 6 1 nan nan NNP cord-308293-8y2iaqnl 7 1 This this DT cord-308293-8y2iaqnl 7 2 letter letter NN cord-308293-8y2iaqnl 7 3 is be VBZ cord-308293-8y2iaqnl 7 4 in in IN cord-308293-8y2iaqnl 7 5 reference reference NN cord-308293-8y2iaqnl 7 6 to to IN cord-308293-8y2iaqnl 7 7 the the DT cord-308293-8y2iaqnl 7 8 study study NN cord-308293-8y2iaqnl 7 9 by by IN cord-308293-8y2iaqnl 7 10 Freedberg Freedberg NNP cord-308293-8y2iaqnl 7 11 et et NNP cord-308293-8y2iaqnl 7 12 al al NNP cord-308293-8y2iaqnl 7 13 1 1 CD cord-308293-8y2iaqnl 7 14 _SP cord-308293-8y2iaqnl 8 1 This this DT cord-308293-8y2iaqnl 8 2 was be VBD cord-308293-8y2iaqnl 8 3 a a DT cord-308293-8y2iaqnl 8 4 retrospective retrospective JJ cord-308293-8y2iaqnl 8 5 analysis analysis NN cord-308293-8y2iaqnl 8 6 of of IN cord-308293-8y2iaqnl 8 7 an an DT cord-308293-8y2iaqnl 8 8 inpatient inpatient JJ cord-308293-8y2iaqnl 8 9 cohort cohort NN cord-308293-8y2iaqnl 8 10 admitted admit VBD cord-308293-8y2iaqnl 8 11 to to IN cord-308293-8y2iaqnl 8 12 two two CD cord-308293-8y2iaqnl 8 13 hospitals hospital NNS cord-308293-8y2iaqnl 8 14 in in IN cord-308293-8y2iaqnl 8 15 New New NNP cord-308293-8y2iaqnl 8 16 York York NNP cord-308293-8y2iaqnl 8 17 , , , cord-308293-8y2iaqnl 8 18 which which WDT cord-308293-8y2iaqnl 8 19 found find VBD cord-308293-8y2iaqnl 8 20 that that IN cord-308293-8y2iaqnl 8 21 COVID-19 covid-19 CD cord-308293-8y2iaqnl 8 22 patients patient NNS cord-308293-8y2iaqnl 8 23 who who WP cord-308293-8y2iaqnl 8 24 were be VBD cord-308293-8y2iaqnl 8 25 treated treat VBN cord-308293-8y2iaqnl 8 26 with with IN cord-308293-8y2iaqnl 8 27 famotidine famotidine NNP cord-308293-8y2iaqnl 8 28 exhibited exhibit VBD cord-308293-8y2iaqnl 8 29 a a DT cord-308293-8y2iaqnl 8 30 lower low JJR cord-308293-8y2iaqnl 8 31 risk risk NN cord-308293-8y2iaqnl 8 32 of of IN cord-308293-8y2iaqnl 8 33 death death NN cord-308293-8y2iaqnl 8 34 or or CC cord-308293-8y2iaqnl 8 35 mechanical mechanical JJ cord-308293-8y2iaqnl 8 36 ventilation ventilation NN cord-308293-8y2iaqnl 8 37 as as IN cord-308293-8y2iaqnl 8 38 composite composite JJ cord-308293-8y2iaqnl 8 39 outcomes outcome NNS cord-308293-8y2iaqnl 8 40 over over IN cord-308293-8y2iaqnl 8 41 a a DT cord-308293-8y2iaqnl 8 42 30-day 30-day CD cord-308293-8y2iaqnl 8 43 period period NN cord-308293-8y2iaqnl 8 44 . . . cord-308293-8y2iaqnl 9 1 The the DT cord-308293-8y2iaqnl 9 2 study study NN cord-308293-8y2iaqnl 9 3 was be VBD cord-308293-8y2iaqnl 9 4 based base VBN cord-308293-8y2iaqnl 9 5 on on IN cord-308293-8y2iaqnl 9 6 computational computational JJ cord-308293-8y2iaqnl 9 7 modelling modelling NN cord-308293-8y2iaqnl 9 8 , , , cord-308293-8y2iaqnl 9 9 which which WDT cord-308293-8y2iaqnl 9 10 proposed propose VBD cord-308293-8y2iaqnl 9 11 famotidine famotidine NNP cord-308293-8y2iaqnl 9 12 might may MD cord-308293-8y2iaqnl 9 13 inhibit inhibit VB cord-308293-8y2iaqnl 9 14 viral viral JJ cord-308293-8y2iaqnl 9 15 replication replication NN cord-308293-8y2iaqnl 9 16 through through IN cord-308293-8y2iaqnl 9 17 direct direct JJ cord-308293-8y2iaqnl 9 18 interaction interaction NN cord-308293-8y2iaqnl 9 19 with with IN cord-308293-8y2iaqnl 9 20 the the DT cord-308293-8y2iaqnl 9 21 3-chymotrypsin 3-chymotrypsin CD cord-308293-8y2iaqnl 9 22 - - HYPH cord-308293-8y2iaqnl 9 23 like like JJ cord-308293-8y2iaqnl 9 24 protease protease NN cord-308293-8y2iaqnl 9 25 2 2 CD cord-308293-8y2iaqnl 9 26 , , , cord-308293-8y2iaqnl 9 27 and and CC cord-308293-8y2iaqnl 9 28 was be VBD cord-308293-8y2iaqnl 9 29 also also RB cord-308293-8y2iaqnl 9 30 preceded precede VBN cord-308293-8y2iaqnl 9 31 by by IN cord-308293-8y2iaqnl 9 32 a a DT cord-308293-8y2iaqnl 9 33 small small JJ cord-308293-8y2iaqnl 9 34 , , , cord-308293-8y2iaqnl 9 35 short short JJ cord-308293-8y2iaqnl 9 36 - - HYPH cord-308293-8y2iaqnl 9 37 term term NN cord-308293-8y2iaqnl 9 38 follow follow NN cord-308293-8y2iaqnl 9 39 - - HYPH cord-308293-8y2iaqnl 9 40 up up NN cord-308293-8y2iaqnl 9 41 , , , cord-308293-8y2iaqnl 9 42 outpatient outpatient NN cord-308293-8y2iaqnl 9 43 study study NN cord-308293-8y2iaqnl 9 44 suggesting suggest VBG cord-308293-8y2iaqnl 9 45 that that IN cord-308293-8y2iaqnl 9 46 famotidine famotidine NNP cord-308293-8y2iaqnl 9 47 use use NN cord-308293-8y2iaqnl 9 48 was be VBD cord-308293-8y2iaqnl 9 49 associated associate VBN cord-308293-8y2iaqnl 9 50 with with IN cord-308293-8y2iaqnl 9 51 symptomatic symptomatic JJ cord-308293-8y2iaqnl 9 52 improvement improvement NN cord-308293-8y2iaqnl 9 53 3 3 CD cord-308293-8y2iaqnl 9 54 . . . cord-308293-8y2iaqnl 10 1 However however RB cord-308293-8y2iaqnl 10 2 , , , cord-308293-8y2iaqnl 10 3 the the DT cord-308293-8y2iaqnl 10 4 current current JJ cord-308293-8y2iaqnl 10 5 study study NN cord-308293-8y2iaqnl 10 6 published publish VBN cord-308293-8y2iaqnl 10 7 in in IN cord-308293-8y2iaqnl 10 8 Gastroenterology Gastroenterology NNP cord-308293-8y2iaqnl 10 9 provides provide VBZ cord-308293-8y2iaqnl 10 10 additional additional JJ cord-308293-8y2iaqnl 10 11 value value NN cord-308293-8y2iaqnl 10 12 as as IN cord-308293-8y2iaqnl 10 13 the the DT cord-308293-8y2iaqnl 10 14 previous previous JJ cord-308293-8y2iaqnl 10 15 cohort cohort NN cord-308293-8y2iaqnl 10 16 was be VBD cord-308293-8y2iaqnl 10 17 much much RB cord-308293-8y2iaqnl 10 18 smaller small JJR cord-308293-8y2iaqnl 10 19 in in IN cord-308293-8y2iaqnl 10 20 number number NN cord-308293-8y2iaqnl 10 21 , , , cord-308293-8y2iaqnl 10 22 included include VBD cord-308293-8y2iaqnl 10 23 patients patient NNS cord-308293-8y2iaqnl 10 24 without without IN cord-308293-8y2iaqnl 10 25 a a DT cord-308293-8y2iaqnl 10 26 proven prove VBN cord-308293-8y2iaqnl 10 27 COVID-19 covid-19 JJ cord-308293-8y2iaqnl 10 28 diagnosis diagnosis NN cord-308293-8y2iaqnl 10 29 , , , cord-308293-8y2iaqnl 10 30 and and CC cord-308293-8y2iaqnl 10 31 lacked lack VBD cord-308293-8y2iaqnl 10 32 a a DT cord-308293-8y2iaqnl 10 33 control control NN cord-308293-8y2iaqnl 10 34 group group NN cord-308293-8y2iaqnl 10 35 . . . cord-308293-8y2iaqnl 11 1 The the DT cord-308293-8y2iaqnl 11 2 current current JJ cord-308293-8y2iaqnl 11 3 study study NN cord-308293-8y2iaqnl 11 4 by by IN cord-308293-8y2iaqnl 11 5 Freedberg Freedberg NNP cord-308293-8y2iaqnl 11 6 et et NNP cord-308293-8y2iaqnl 11 7 al al NNP cord-308293-8y2iaqnl 11 8 1 1 CD cord-308293-8y2iaqnl 11 9 brings bring VBZ cord-308293-8y2iaqnl 11 10 a a DT cord-308293-8y2iaqnl 11 11 few few JJ cord-308293-8y2iaqnl 11 12 questions question NNS cord-308293-8y2iaqnl 11 13 to to TO cord-308293-8y2iaqnl 11 14 mind mind VB cord-308293-8y2iaqnl 11 15 , , , cord-308293-8y2iaqnl 11 16 which which WDT cord-308293-8y2iaqnl 11 17 we -PRON- PRP cord-308293-8y2iaqnl 11 18 hope hope VBP cord-308293-8y2iaqnl 11 19 the the DT cord-308293-8y2iaqnl 11 20 authors author NNS cord-308293-8y2iaqnl 11 21 can can MD cord-308293-8y2iaqnl 11 22 answer answer VB cord-308293-8y2iaqnl 11 23 . . . cord-308293-8y2iaqnl 12 1 In in IN cord-308293-8y2iaqnl 12 2 the the DT cord-308293-8y2iaqnl 12 3 conclusions conclusion NNS cord-308293-8y2iaqnl 12 4 , , , cord-308293-8y2iaqnl 12 5 the the DT cord-308293-8y2iaqnl 12 6 authors author NNS cord-308293-8y2iaqnl 12 7 stated state VBD cord-308293-8y2iaqnl 12 8 , , , cord-308293-8y2iaqnl 12 9 " " `` cord-308293-8y2iaqnl 12 10 The the DT cord-308293-8y2iaqnl 12 11 study study NN cord-308293-8y2iaqnl 12 12 was be VBD cord-308293-8y2iaqnl 12 13 premised premise VBN cord-308293-8y2iaqnl 12 14 on on IN cord-308293-8y2iaqnl 12 15 the the DT cord-308293-8y2iaqnl 12 16 assumption assumption NN cord-308293-8y2iaqnl 12 17 that that IN cord-308293-8y2iaqnl 12 18 use use NN cord-308293-8y2iaqnl 12 19 of of IN cord-308293-8y2iaqnl 12 20 famotidine famotidine NN cord-308293-8y2iaqnl 12 21 represented represent VBD cord-308293-8y2iaqnl 12 22 a a DT cord-308293-8y2iaqnl 12 23 continuation continuation NN cord-308293-8y2iaqnl 12 24 of of IN cord-308293-8y2iaqnl 12 25 home home NN cord-308293-8y2iaqnl 12 26 use use NN cord-308293-8y2iaqnl 12 27 " " '' cord-308293-8y2iaqnl 12 28 . . . cord-308293-8y2iaqnl 13 1 In in IN cord-308293-8y2iaqnl 13 2 the the DT cord-308293-8y2iaqnl 13 3 results result NNS cord-308293-8y2iaqnl 13 4 section section NN cord-308293-8y2iaqnl 13 5 they -PRON- PRP cord-308293-8y2iaqnl 13 6 also also RB cord-308293-8y2iaqnl 13 7 say say VBP cord-308293-8y2iaqnl 13 8 " " `` cord-308293-8y2iaqnl 13 9 Home home NN cord-308293-8y2iaqnl 13 10 use use NN cord-308293-8y2iaqnl 13 11 of of IN cord-308293-8y2iaqnl 13 12 famotidine famotidine NN cord-308293-8y2iaqnl 13 13 was be VBD cord-308293-8y2iaqnl 13 14 documented document VBN cord-308293-8y2iaqnl 13 15 on on IN cord-308293-8y2iaqnl 13 16 admission admission NN cord-308293-8y2iaqnl 13 17 medication medication NN cord-308293-8y2iaqnl 13 18 reconciliation reconciliation NN cord-308293-8y2iaqnl 13 19 in in IN cord-308293-8y2iaqnl 13 20 15 15 CD cord-308293-8y2iaqnl 13 21 % % NN cord-308293-8y2iaqnl 13 22 of of IN cord-308293-8y2iaqnl 13 23 those those DT cord-308293-8y2iaqnl 13 24 who who WP cord-308293-8y2iaqnl 13 25 used use VBD cord-308293-8y2iaqnl 13 26 famotidine famotidine NN cord-308293-8y2iaqnl 13 27 while while IN cord-308293-8y2iaqnl 13 28 hospitalized hospitalize VBN cord-308293-8y2iaqnl 13 29 " " '' cord-308293-8y2iaqnl 13 30 . . . cord-308293-8y2iaqnl 14 1 These these DT cord-308293-8y2iaqnl 14 2 bring bring VBP cord-308293-8y2iaqnl 14 3 up up RP cord-308293-8y2iaqnl 14 4 a a DT cord-308293-8y2iaqnl 14 5 few few JJ cord-308293-8y2iaqnl 14 6 questions question NNS cord-308293-8y2iaqnl 14 7 : : : cord-308293-8y2iaqnl 14 8 1 1 LS cord-308293-8y2iaqnl 14 9 ) ) -RRB- cord-308293-8y2iaqnl 14 10 Does do VBZ cord-308293-8y2iaqnl 14 11 this this DT cord-308293-8y2iaqnl 14 12 indicate indicate VB cord-308293-8y2iaqnl 14 13 that that IN cord-308293-8y2iaqnl 14 14 the the DT cord-308293-8y2iaqnl 14 15 remaining remain VBG cord-308293-8y2iaqnl 14 16 85 85 CD cord-308293-8y2iaqnl 14 17 % % NN cord-308293-8y2iaqnl 14 18 patients patient NNS cord-308293-8y2iaqnl 14 19 given give VBN cord-308293-8y2iaqnl 14 20 famotidine famotidine NN cord-308293-8y2iaqnl 14 21 during during IN cord-308293-8y2iaqnl 14 22 hospitalization hospitalization NN cord-308293-8y2iaqnl 14 23 were be VBD cord-308293-8y2iaqnl 14 24 using use VBG cord-308293-8y2iaqnl 14 25 over over IN cord-308293-8y2iaqnl 14 26 the the DT cord-308293-8y2iaqnl 14 27 counter counter NN cord-308293-8y2iaqnl 14 28 formulations formulation NNS cord-308293-8y2iaqnl 14 29 at at IN cord-308293-8y2iaqnl 14 30 home home NN cord-308293-8y2iaqnl 14 31 which which WDT cord-308293-8y2iaqnl 14 32 were be VBD cord-308293-8y2iaqnl 14 33 not not RB cord-308293-8y2iaqnl 14 34 prescribed prescribe VBN cord-308293-8y2iaqnl 14 35 by by IN cord-308293-8y2iaqnl 14 36 a a DT cord-308293-8y2iaqnl 14 37 physician physician NN cord-308293-8y2iaqnl 14 38 ? ? . cord-308293-8y2iaqnl 15 1 2 2 LS cord-308293-8y2iaqnl 15 2 ) ) -RRB- cord-308293-8y2iaqnl 15 3 Were be VBD cord-308293-8y2iaqnl 15 4 these these DT cord-308293-8y2iaqnl 15 5 formulations formulation NNS cord-308293-8y2iaqnl 15 6 continued continue VBD cord-308293-8y2iaqnl 15 7 in in IN cord-308293-8y2iaqnl 15 8 - - HYPH cord-308293-8y2iaqnl 15 9 patient patient NN cord-308293-8y2iaqnl 15 10 ? ? . cord-308293-8y2iaqnl 16 1 3 3 LS cord-308293-8y2iaqnl 16 2 ) ) -RRB- cord-308293-8y2iaqnl 17 1 What what WP cord-308293-8y2iaqnl 17 2 were be VBD cord-308293-8y2iaqnl 17 3 the the DT cord-308293-8y2iaqnl 17 4 formulations formulation NNS cord-308293-8y2iaqnl 17 5 of of IN cord-308293-8y2iaqnl 17 6 famotidine famotidine NN cord-308293-8y2iaqnl 17 7 used use VBN cord-308293-8y2iaqnl 17 8 by by IN cord-308293-8y2iaqnl 17 9 the the DT cord-308293-8y2iaqnl 17 10 hospital hospital NN cord-308293-8y2iaqnl 17 11 pharmacies pharmacy NNS cord-308293-8y2iaqnl 17 12 ? ? . cord-308293-8y2iaqnl 18 1 4 4 LS cord-308293-8y2iaqnl 18 2 ) ) -RRB- cord-308293-8y2iaqnl 19 1 Did do VBD cord-308293-8y2iaqnl 19 2 some some DT cord-308293-8y2iaqnl 19 3 included include VBN cord-308293-8y2iaqnl 19 4 patients patient NNS cord-308293-8y2iaqnl 19 5 receive receive VB cord-308293-8y2iaqnl 19 6 concomitant concomitant JJ cord-308293-8y2iaqnl 19 7 treatment treatment NN cord-308293-8y2iaqnl 19 8 with with IN cord-308293-8y2iaqnl 19 9 antacids antacid NNS cord-308293-8y2iaqnl 19 10 , , , cord-308293-8y2iaqnl 19 11 particularly particularly RB cord-308293-8y2iaqnl 19 12 calcium calcium NN cord-308293-8y2iaqnl 19 13 - - HYPH cord-308293-8y2iaqnl 19 14 containing contain VBG cord-308293-8y2iaqnl 19 15 compounds compound NNS cord-308293-8y2iaqnl 19 16 ? ? . cord-308293-8y2iaqnl 20 1 5 5 LS cord-308293-8y2iaqnl 20 2 ) ) -RRB- cord-308293-8y2iaqnl 21 1 It -PRON- PRP cord-308293-8y2iaqnl 21 2 is be VBZ cord-308293-8y2iaqnl 21 3 also also RB cord-308293-8y2iaqnl 21 4 mentioned mention VBN cord-308293-8y2iaqnl 21 5 that that IN cord-308293-8y2iaqnl 21 6 28 28 CD cord-308293-8y2iaqnl 21 7 % % NN cord-308293-8y2iaqnl 21 8 hospitalized hospitalize VBD cord-308293-8y2iaqnl 21 9 COVID-19 COVID-19 , cord-308293-8y2iaqnl 21 10 patients patient NNS cord-308293-8y2iaqnl 21 11 received receive VBD cord-308293-8y2iaqnl 21 12 famotidine famotidine NNP cord-308293-8y2iaqnl 21 13 intravenously intravenously RB cord-308293-8y2iaqnl 21 14 . . . cord-308293-8y2iaqnl 22 1 Was be VBD cord-308293-8y2iaqnl 22 2 there there EX cord-308293-8y2iaqnl 22 3 a a DT cord-308293-8y2iaqnl 22 4 difference difference NN cord-308293-8y2iaqnl 22 5 in in IN cord-308293-8y2iaqnl 22 6 outcomes outcome NNS cord-308293-8y2iaqnl 22 7 between between IN cord-308293-8y2iaqnl 22 8 the the DT cord-308293-8y2iaqnl 22 9 intravenously intravenously RB cord-308293-8y2iaqnl 22 10 treated treat VBN cord-308293-8y2iaqnl 22 11 group group NN cord-308293-8y2iaqnl 22 12 and and CC cord-308293-8y2iaqnl 22 13 the the DT cord-308293-8y2iaqnl 22 14 orally orally RB cord-308293-8y2iaqnl 22 15 treated treat VBN cord-308293-8y2iaqnl 22 16 group group NN cord-308293-8y2iaqnl 22 17 ? ? . cord-308293-8y2iaqnl 23 1 We -PRON- PRP cord-308293-8y2iaqnl 23 2 ask ask VBP cord-308293-8y2iaqnl 23 3 since since IN cord-308293-8y2iaqnl 23 4 popular popular JJ cord-308293-8y2iaqnl 23 5 over over IN cord-308293-8y2iaqnl 23 6 the the DT cord-308293-8y2iaqnl 23 7 counter counter JJ cord-308293-8y2iaqnl 23 8 famotidine famotidine NN cord-308293-8y2iaqnl 23 9 formulations formulation NNS cord-308293-8y2iaqnl 23 10 such such JJ cord-308293-8y2iaqnl 23 11 as as IN cord-308293-8y2iaqnl 23 12 Pepcid Pepcid NNP cord-308293-8y2iaqnl 23 13 complete complete NN cord-308293-8y2iaqnl 23 14 ® ® VBP cord-308293-8y2iaqnl 23 15 commonly commonly RB cord-308293-8y2iaqnl 23 16 contain contain VB cord-308293-8y2iaqnl 23 17 800 800 CD cord-308293-8y2iaqnl 23 18 mg mg NN cord-308293-8y2iaqnl 23 19 calcium calcium NN cord-308293-8y2iaqnl 23 20 carbonate carbonate NN cord-308293-8y2iaqnl 23 21 per per IN cord-308293-8y2iaqnl 23 22 10 10 CD cord-308293-8y2iaqnl 23 23 mg mg NNP cord-308293-8y2iaqnl 23 24 famotidine famotidine NN cord-308293-8y2iaqnl 23 25 . . . cord-308293-8y2iaqnl 24 1 The the DT cord-308293-8y2iaqnl 24 2 answers answer NNS cord-308293-8y2iaqnl 24 3 to to IN cord-308293-8y2iaqnl 24 4 these these DT cord-308293-8y2iaqnl 24 5 questions question NNS cord-308293-8y2iaqnl 24 6 are be VBP cord-308293-8y2iaqnl 24 7 pathophysiologically pathophysiologically RB cord-308293-8y2iaqnl 24 8 relevant relevant JJ cord-308293-8y2iaqnl 24 9 as as IN cord-308293-8y2iaqnl 24 10 we -PRON- PRP cord-308293-8y2iaqnl 24 11 have have VBP cord-308293-8y2iaqnl 24 12 recently recently RB cord-308293-8y2iaqnl 24 13 published publish VBN cord-308293-8y2iaqnl 24 14 a a DT cord-308293-8y2iaqnl 24 15 report report NN cord-308293-8y2iaqnl 24 16 in in IN cord-308293-8y2iaqnl 24 17 your -PRON- PRP$ cord-308293-8y2iaqnl 24 18 journal journal NN cord-308293-8y2iaqnl 24 19 4 4 CD cord-308293-8y2iaqnl 24 20 , , , cord-308293-8y2iaqnl 24 21 suggesting suggest VBG cord-308293-8y2iaqnl 24 22 that that IN cord-308293-8y2iaqnl 24 23 the the DT cord-308293-8y2iaqnl 24 24 hypocalcemia hypocalcemia NN cord-308293-8y2iaqnl 24 25 commonly commonly RB cord-308293-8y2iaqnl 24 26 seen see VBN cord-308293-8y2iaqnl 24 27 in in IN cord-308293-8y2iaqnl 24 28 severe severe JJ cord-308293-8y2iaqnl 24 29 COVID-19 covid-19 JJ cord-308293-8y2iaqnl 24 30 disease disease NN cord-308293-8y2iaqnl 24 31 is be VBZ cord-308293-8y2iaqnl 24 32 prognostically prognostically RB cord-308293-8y2iaqnl 24 33 and and CC cord-308293-8y2iaqnl 24 34 mechanistically mechanistically RB cord-308293-8y2iaqnl 24 35 relevant relevant JJ cord-308293-8y2iaqnl 24 36 to to IN cord-308293-8y2iaqnl 24 37 disease disease NN cord-308293-8y2iaqnl 24 38 outcomes outcome NNS cord-308293-8y2iaqnl 24 39 . . . cord-308293-8y2iaqnl 25 1 We -PRON- PRP cord-308293-8y2iaqnl 25 2 proposed propose VBD cord-308293-8y2iaqnl 25 3 that that IN cord-308293-8y2iaqnl 25 4 calcium calcium NN cord-308293-8y2iaqnl 25 5 supplementation supplementation NN cord-308293-8y2iaqnl 25 6 early early RB cord-308293-8y2iaqnl 25 7 in in IN cord-308293-8y2iaqnl 25 8 the the DT cord-308293-8y2iaqnl 25 9 disease disease NN cord-308293-8y2iaqnl 25 10 can can MD cord-308293-8y2iaqnl 25 11 , , , cord-308293-8y2iaqnl 25 12 by by IN cord-308293-8y2iaqnl 25 13 interacting interact VBG cord-308293-8y2iaqnl 25 14 with with IN cord-308293-8y2iaqnl 25 15 fatty fatty JJ cord-308293-8y2iaqnl 25 16 acids acid NNS cord-308293-8y2iaqnl 25 17 , , , cord-308293-8y2iaqnl 25 18 reduce reduce VB cord-308293-8y2iaqnl 25 19 the the DT cord-308293-8y2iaqnl 25 20 lipotoxicity lipotoxicity NN cord-308293-8y2iaqnl 25 21 which which WDT cord-308293-8y2iaqnl 25 22 may may MD cord-308293-8y2iaqnl 25 23 exacerbate exacerbate VB cord-308293-8y2iaqnl 25 24 the the DT cord-308293-8y2iaqnl 25 25 disease disease NN cord-308293-8y2iaqnl 25 26 , , , cord-308293-8y2iaqnl 25 27 and and CC cord-308293-8y2iaqnl 25 28 result result VB cord-308293-8y2iaqnl 25 29 in in IN cord-308293-8y2iaqnl 25 30 organ organ NN cord-308293-8y2iaqnl 25 31 failure failure NN cord-308293-8y2iaqnl 25 32 . . . cord-308293-8y2iaqnl 26 1 Using use VBG cord-308293-8y2iaqnl 26 2 in in IN cord-308293-8y2iaqnl 26 3 silico silico NN cord-308293-8y2iaqnl 26 4 molecular molecular JJ cord-308293-8y2iaqnl 26 5 docking docking NN cord-308293-8y2iaqnl 26 6 screens screen NNS cord-308293-8y2iaqnl 26 7 , , , cord-308293-8y2iaqnl 26 8 famotidine famotidine NNP cord-308293-8y2iaqnl 26 9 has have VBZ cord-308293-8y2iaqnl 26 10 been be VBN cord-308293-8y2iaqnl 26 11 characterized characterize VBN cord-308293-8y2iaqnl 26 12 as as IN cord-308293-8y2iaqnl 26 13 potentially potentially RB cord-308293-8y2iaqnl 26 14 being be VBG cord-308293-8y2iaqnl 26 15 able able JJ cord-308293-8y2iaqnl 26 16 to to TO cord-308293-8y2iaqnl 26 17 bind bind VB cord-308293-8y2iaqnl 26 18 papain papain NN cord-308293-8y2iaqnl 26 19 - - HYPH cord-308293-8y2iaqnl 26 20 like like JJ cord-308293-8y2iaqnl 26 21 protease protease NN cord-308293-8y2iaqnl 26 22 ( ( -LRB- cord-308293-8y2iaqnl 26 23 PLpro PLpro NNP cord-308293-8y2iaqnl 26 24 ) ) -RRB- cord-308293-8y2iaqnl 26 25 and and CC cord-308293-8y2iaqnl 26 26 3 3 CD cord-308293-8y2iaqnl 26 27 chymotrypsin chymotrypsin VB cord-308293-8y2iaqnl 26 28 - - HYPH cord-308293-8y2iaqnl 26 29 like like JJ cord-308293-8y2iaqnl 26 30 protease protease NN cord-308293-8y2iaqnl 26 31 ( ( -LRB- cord-308293-8y2iaqnl 26 32 Mpro Mpro NNP cord-308293-8y2iaqnl 26 33 ) ) -RRB- cord-308293-8y2iaqnl 26 34 of of IN cord-308293-8y2iaqnl 26 35 SARS SARS NNP cord-308293-8y2iaqnl 26 36 - - HYPH cord-308293-8y2iaqnl 26 37 CoV-2 CoV-2 NNP cord-308293-8y2iaqnl 26 38 2 2 CD cord-308293-8y2iaqnl 26 39 5 5 CD cord-308293-8y2iaqnl 26 40 . . . cord-308293-8y2iaqnl 27 1 To to TO cord-308293-8y2iaqnl 27 2 explore explore VB cord-308293-8y2iaqnl 27 3 this this DT cord-308293-8y2iaqnl 27 4 further further RB cord-308293-8y2iaqnl 27 5 , , , cord-308293-8y2iaqnl 27 6 we -PRON- PRP cord-308293-8y2iaqnl 27 7 downloaded download VBD cord-308293-8y2iaqnl 27 8 crystal crystal NN cord-308293-8y2iaqnl 27 9 structures structure NNS cord-308293-8y2iaqnl 27 10 of of IN cord-308293-8y2iaqnl 27 11 PLpro PLpro NNP cord-308293-8y2iaqnl 27 12 and and CC cord-308293-8y2iaqnl 27 13 Mpro Mpro NNP cord-308293-8y2iaqnl 27 14 from from IN cord-308293-8y2iaqnl 27 15 RCSB.org RCSB.org NNP cord-308293-8y2iaqnl 27 16 ( ( -LRB- cord-308293-8y2iaqnl 27 17 PDB PDB NNP cord-308293-8y2iaqnl 27 18 IDs id NNS cord-308293-8y2iaqnl 27 19 6WX4 6wx4 CD cord-308293-8y2iaqnl 27 20 and and CC cord-308293-8y2iaqnl 27 21 6LU7 6lu7 CD cord-308293-8y2iaqnl 27 22 , , , cord-308293-8y2iaqnl 27 23 respectively respectively RB cord-308293-8y2iaqnl 27 24 ) ) -RRB- cord-308293-8y2iaqnl 27 25 and and CC cord-308293-8y2iaqnl 27 26 imported import VBD cord-308293-8y2iaqnl 27 27 these these DT cord-308293-8y2iaqnl 27 28 to to IN cord-308293-8y2iaqnl 27 29 Schrodinger Schrodinger NNP cord-308293-8y2iaqnl 27 30 Maestro Maestro NNP cord-308293-8y2iaqnl 27 31 . . . cord-308293-8y2iaqnl 28 1 The the DT cord-308293-8y2iaqnl 28 2 structures structure NNS cord-308293-8y2iaqnl 28 3 were be VBD cord-308293-8y2iaqnl 28 4 prepared prepare VBN cord-308293-8y2iaqnl 28 5 for for IN cord-308293-8y2iaqnl 28 6 docking docking NN cord-308293-8y2iaqnl 28 7 , , , cord-308293-8y2iaqnl 28 8 and and CC cord-308293-8y2iaqnl 28 9 famotidine famotidine NN cord-308293-8y2iaqnl 28 10 was be VBD cord-308293-8y2iaqnl 28 11 docked dock VBN cord-308293-8y2iaqnl 28 12 to to IN cord-308293-8y2iaqnl 28 13 both both DT cord-308293-8y2iaqnl 28 14 proteases protease NNS cord-308293-8y2iaqnl 28 15 using use VBG cord-308293-8y2iaqnl 28 16 the the DT cord-308293-8y2iaqnl 28 17 XP XP NNP cord-308293-8y2iaqnl 28 18 docking docking NN cord-308293-8y2iaqnl 28 19 protocol protocol NN cord-308293-8y2iaqnl 28 20 . . . cord-308293-8y2iaqnl 29 1 Famotidine Famotidine NNP cord-308293-8y2iaqnl 29 2 was be VBD cord-308293-8y2iaqnl 29 3 found find VBN cord-308293-8y2iaqnl 29 4 to to TO cord-308293-8y2iaqnl 29 5 dock dock VB cord-308293-8y2iaqnl 29 6 to to IN cord-308293-8y2iaqnl 29 7 PLpro PLpro NNP cord-308293-8y2iaqnl 29 8 with with IN cord-308293-8y2iaqnl 29 9 a a DT cord-308293-8y2iaqnl 29 10 GlideScore GlideScore NNP cord-308293-8y2iaqnl 29 11 of of IN cord-308293-8y2iaqnl 29 12 -6.86 -6.86 : cord-308293-8y2iaqnl 29 13 kcal kcal NNP cord-308293-8y2iaqnl 29 14 / / SYM cord-308293-8y2iaqnl 29 15 mol mol NN cord-308293-8y2iaqnl 29 16 and and CC cord-308293-8y2iaqnl 29 17 to to IN cord-308293-8y2iaqnl 29 18 Mpro Mpro NNP cord-308293-8y2iaqnl 29 19 with with IN cord-308293-8y2iaqnl 29 20 a a DT cord-308293-8y2iaqnl 29 21 GlideScore GlideScore NNP cord-308293-8y2iaqnl 29 22 of of IN cord-308293-8y2iaqnl 29 23 -4.05 -4.05 CD cord-308293-8y2iaqnl 29 24 kcal kcal NNP cord-308293-8y2iaqnl 29 25 / / SYM cord-308293-8y2iaqnl 29 26 mol mol NN cord-308293-8y2iaqnl 29 27 . . . cord-308293-8y2iaqnl 30 1 This this DT cord-308293-8y2iaqnl 30 2 represents represent VBZ cord-308293-8y2iaqnl 30 3 weak weak JJ cord-308293-8y2iaqnl 30 4 , , , cord-308293-8y2iaqnl 30 5 nonspecific nonspecific JJ cord-308293-8y2iaqnl 30 6 binding binding NN cord-308293-8y2iaqnl 30 7 of of IN cord-308293-8y2iaqnl 30 8 famotidine famotidine NN cord-308293-8y2iaqnl 30 9 to to IN cord-308293-8y2iaqnl 30 10 both both DT cord-308293-8y2iaqnl 30 11 PLpro PLpro NNP cord-308293-8y2iaqnl 30 12 and and CC cord-308293-8y2iaqnl 30 13 Mpro Mpro NNP cord-308293-8y2iaqnl 30 14 , , , cord-308293-8y2iaqnl 30 15 and and CC cord-308293-8y2iaqnl 30 16 is be VBZ cord-308293-8y2iaqnl 30 17 in in IN cord-308293-8y2iaqnl 30 18 contradiction contradiction NN cord-308293-8y2iaqnl 30 19 to to IN cord-308293-8y2iaqnl 30 20 previous previous JJ cord-308293-8y2iaqnl 30 21 molecular molecular JJ cord-308293-8y2iaqnl 30 22 docking docking NN cord-308293-8y2iaqnl 30 23 studies study NNS cord-308293-8y2iaqnl 30 24 . . . cord-308293-8y2iaqnl 31 1 Recently recently RB cord-308293-8y2iaqnl 31 2 , , , cord-308293-8y2iaqnl 31 3 in in IN cord-308293-8y2iaqnl 31 4 vitro vitro FW cord-308293-8y2iaqnl 31 5 experiments experiment NNS cord-308293-8y2iaqnl 31 6 have have VBP cord-308293-8y2iaqnl 31 7 shown show VBN cord-308293-8y2iaqnl 31 8 that that IN cord-308293-8y2iaqnl 31 9 famotidine famotidine NN cord-308293-8y2iaqnl 31 10 DOES do VBZ cord-308293-8y2iaqnl 31 11 NOT not RB cord-308293-8y2iaqnl 31 12 inhibit inhibit VB cord-308293-8y2iaqnl 31 13 PLpro PLpro NNP cord-308293-8y2iaqnl 31 14 or or CC cord-308293-8y2iaqnl 31 15 Mpro Mpro NNP cord-308293-8y2iaqnl 31 16 , , , cord-308293-8y2iaqnl 31 17 and and CC cord-308293-8y2iaqnl 31 18 it -PRON- PRP cord-308293-8y2iaqnl 31 19 does do VBZ cord-308293-8y2iaqnl 31 20 not not RB cord-308293-8y2iaqnl 31 21 directly directly RB cord-308293-8y2iaqnl 31 22 inhibit inhibit VB cord-308293-8y2iaqnl 31 23 SARS SARS NNP cord-308293-8y2iaqnl 31 24 - - HYPH cord-308293-8y2iaqnl 31 25 CoV-2 CoV-2 NNP cord-308293-8y2iaqnl 31 26 infection infection NN cord-308293-8y2iaqnl 31 27 6 6 CD cord-308293-8y2iaqnl 31 28 7 7 CD cord-308293-8y2iaqnl 31 29 , , , cord-308293-8y2iaqnl 31 30 supporting support VBG cord-308293-8y2iaqnl 31 31 our -PRON- PRP$ cord-308293-8y2iaqnl 31 32 molecular molecular JJ cord-308293-8y2iaqnl 31 33 docking docking NN cord-308293-8y2iaqnl 31 34 data datum NNS cord-308293-8y2iaqnl 31 35 that that WDT cord-308293-8y2iaqnl 31 36 famotidine famotidine NNP cord-308293-8y2iaqnl 31 37 does do VBZ cord-308293-8y2iaqnl 31 38 not not RB cord-308293-8y2iaqnl 31 39 bind bind VB cord-308293-8y2iaqnl 31 40 to to IN cord-308293-8y2iaqnl 31 41 either either DT cord-308293-8y2iaqnl 31 42 protease protease NN cord-308293-8y2iaqnl 31 43 . . . cord-308293-8y2iaqnl 32 1 It -PRON- PRP cord-308293-8y2iaqnl 32 2 has have VBZ cord-308293-8y2iaqnl 32 3 been be VBN cord-308293-8y2iaqnl 32 4 hypothesized hypothesize VBN cord-308293-8y2iaqnl 32 5 that that IN cord-308293-8y2iaqnl 32 6 famotidine famotidine NNP cord-308293-8y2iaqnl 32 7 could could MD cord-308293-8y2iaqnl 32 8 indirectly indirectly RB cord-308293-8y2iaqnl 32 9 treat treat VB cord-308293-8y2iaqnl 32 10 COVID-19 COVID-19 NNP cord-308293-8y2iaqnl 32 11 through through IN cord-308293-8y2iaqnl 32 12 antagonism antagonism NN cord-308293-8y2iaqnl 32 13 or or CC cord-308293-8y2iaqnl 32 14 inverse inverse JJ cord-308293-8y2iaqnl 32 15 agonism agonism NN cord-308293-8y2iaqnl 32 16 of of IN cord-308293-8y2iaqnl 32 17 histamine histamine NN cord-308293-8y2iaqnl 32 18 signaling signal VBG cord-308293-8y2iaqnl 32 19 as as IN cord-308293-8y2iaqnl 32 20 a a DT cord-308293-8y2iaqnl 32 21 result result NN cord-308293-8y2iaqnl 32 22 of of IN cord-308293-8y2iaqnl 32 23 binding bind VBG cord-308293-8y2iaqnl 32 24 to to IN cord-308293-8y2iaqnl 32 25 the the DT cord-308293-8y2iaqnl 32 26 H2 H2 NNP cord-308293-8y2iaqnl 32 27 receptor receptor NN cord-308293-8y2iaqnl 32 28 6 6 CD cord-308293-8y2iaqnl 32 29 , , , cord-308293-8y2iaqnl 32 30 but but CC cord-308293-8y2iaqnl 32 31 this this DT cord-308293-8y2iaqnl 32 32 has have VBZ cord-308293-8y2iaqnl 32 33 yet yet RB cord-308293-8y2iaqnl 32 34 to to TO cord-308293-8y2iaqnl 32 35 be be VB cord-308293-8y2iaqnl 32 36 rigorously rigorously RB cord-308293-8y2iaqnl 32 37 tested test VBN cord-308293-8y2iaqnl 32 38 . . . cord-308293-8y2iaqnl 33 1 While while IN cord-308293-8y2iaqnl 33 2 results result NNS cord-308293-8y2iaqnl 33 3 of of IN cord-308293-8y2iaqnl 33 4 the the DT cord-308293-8y2iaqnl 33 5 randomized randomized JJ cord-308293-8y2iaqnl 33 6 clinical clinical JJ cord-308293-8y2iaqnl 33 7 trial trial NN cord-308293-8y2iaqnl 33 8 on on IN cord-308293-8y2iaqnl 33 9 the the DT cord-308293-8y2iaqnl 33 10 benefits benefit NNS cord-308293-8y2iaqnl 33 11 of of IN cord-308293-8y2iaqnl 33 12 intravenous intravenous JJ cord-308293-8y2iaqnl 33 13 famotidine famotidine NN cord-308293-8y2iaqnl 33 14 in in IN cord-308293-8y2iaqnl 33 15 treating treat VBG cord-308293-8y2iaqnl 33 16 COVID-19 COVID-19 NNP cord-308293-8y2iaqnl 33 17 ( ( -LRB- cord-308293-8y2iaqnl 33 18 NCT04370262 NCT04370262 NNP cord-308293-8y2iaqnl 33 19 ) ) -RRB- cord-308293-8y2iaqnl 33 20 are be VBP cord-308293-8y2iaqnl 33 21 excitedly excitedly RB cord-308293-8y2iaqnl 33 22 awaited await VBN cord-308293-8y2iaqnl 33 23 ; ; : cord-308293-8y2iaqnl 33 24 the the DT cord-308293-8y2iaqnl 33 25 clues clue NNS cord-308293-8y2iaqnl 33 26 gained gain VBN cord-308293-8y2iaqnl 33 27 by by IN cord-308293-8y2iaqnl 33 28 the the DT cord-308293-8y2iaqnl 33 29 studies study NNS cord-308293-8y2iaqnl 33 30 published publish VBN cord-308293-8y2iaqnl 33 31 in in IN cord-308293-8y2iaqnl 33 32 both both DT cord-308293-8y2iaqnl 33 33 Gastroenterology Gastroenterology NNP cord-308293-8y2iaqnl 33 34 1 1 CD cord-308293-8y2iaqnl 33 35 4 4 CD cord-308293-8y2iaqnl 33 36 and and CC cord-308293-8y2iaqnl 33 37 Gut Gut NNP cord-308293-8y2iaqnl 33 38 3 3 CD cord-308293-8y2iaqnl 33 39 , , , cord-308293-8y2iaqnl 33 40 give give VB cord-308293-8y2iaqnl 33 41 hope hope NN cord-308293-8y2iaqnl 33 42 that that IN cord-308293-8y2iaqnl 33 43 COVID-19 COVID-19 NNP cord-308293-8y2iaqnl 33 44 could could MD cord-308293-8y2iaqnl 33 45 be be VB cord-308293-8y2iaqnl 33 46 combated combat VBN cord-308293-8y2iaqnl 33 47 by by IN cord-308293-8y2iaqnl 33 48 delving delve VBG cord-308293-8y2iaqnl 33 49 deeper deeply RBR cord-308293-8y2iaqnl 33 50 into into IN cord-308293-8y2iaqnl 33 51 , , , cord-308293-8y2iaqnl 33 52 and and CC cord-308293-8y2iaqnl 33 53 understanding understand VBG cord-308293-8y2iaqnl 33 54 the the DT cord-308293-8y2iaqnl 33 55 mechanistic mechanistic JJ cord-308293-8y2iaqnl 33 56 basis basis NN cord-308293-8y2iaqnl 33 57 of of IN cord-308293-8y2iaqnl 33 58 what what WP cord-308293-8y2iaqnl 33 59 was be VBD cord-308293-8y2iaqnl 33 60 observed observe VBN cord-308293-8y2iaqnl 33 61 . . . cord-308293-8y2iaqnl 34 1 Famotidine Famotidine NNP cord-308293-8y2iaqnl 34 2 Use Use NNP cord-308293-8y2iaqnl 34 3 is be VBZ cord-308293-8y2iaqnl 34 4 Associated associate VBN cord-308293-8y2iaqnl 34 5 with with IN cord-308293-8y2iaqnl 34 6 Improved Improved NNP cord-308293-8y2iaqnl 34 7 Clinical Clinical NNP cord-308293-8y2iaqnl 34 8 Outcomes Outcomes NNPS cord-308293-8y2iaqnl 34 9 in in IN cord-308293-8y2iaqnl 34 10 Hospitalized Hospitalized NNP cord-308293-8y2iaqnl 34 11 COVID-19 COVID-19 NNP cord-308293-8y2iaqnl 34 12 Patients patient NNS cord-308293-8y2iaqnl 34 13 : : : cord-308293-8y2iaqnl 35 1 A a DT cord-308293-8y2iaqnl 36 1 Propensity propensity NN cord-308293-8y2iaqnl 36 2 Score Score NNP cord-308293-8y2iaqnl 36 3 Matched match VBD cord-308293-8y2iaqnl 36 4 Retrospective Retrospective NNP cord-308293-8y2iaqnl 36 5 Cohort Cohort NNP cord-308293-8y2iaqnl 36 6 Study Study NNP cord-308293-8y2iaqnl 36 7 Analysis Analysis NNP cord-308293-8y2iaqnl 36 8 of of IN cord-308293-8y2iaqnl 36 9 therapeutic therapeutic JJ cord-308293-8y2iaqnl 36 10 targets target NNS cord-308293-8y2iaqnl 36 11 for for IN cord-308293-8y2iaqnl 36 12 SARS SARS NNP cord-308293-8y2iaqnl 36 13 - - HYPH cord-308293-8y2iaqnl 36 14 CoV-2 CoV-2 NNP cord-308293-8y2iaqnl 36 15 and and CC cord-308293-8y2iaqnl 36 16 discovery discovery NN cord-308293-8y2iaqnl 36 17 of of IN cord-308293-8y2iaqnl 36 18 potential potential JJ cord-308293-8y2iaqnl 36 19 drugs drug NNS cord-308293-8y2iaqnl 36 20 by by IN cord-308293-8y2iaqnl 36 21 computational computational JJ cord-308293-8y2iaqnl 36 22 methods method NNS cord-308293-8y2iaqnl 37 1 Famotidine Famotidine NNP cord-308293-8y2iaqnl 37 2 use use NN cord-308293-8y2iaqnl 37 3 and and CC cord-308293-8y2iaqnl 37 4 quantitative quantitative JJ cord-308293-8y2iaqnl 37 5 symptom symptom NN cord-308293-8y2iaqnl 37 6 tracking tracking NN cord-308293-8y2iaqnl 37 7 for for IN cord-308293-8y2iaqnl 37 8 COVID-19 COVID-19 NNP cord-308293-8y2iaqnl 37 9 in in IN cord-308293-8y2iaqnl 37 10 non non JJ cord-308293-8y2iaqnl 37 11 - - JJ cord-308293-8y2iaqnl 37 12 hospitalised hospitalised JJ cord-308293-8y2iaqnl 37 13 patients patient NNS cord-308293-8y2iaqnl 37 14 : : : cord-308293-8y2iaqnl 37 15 a a DT cord-308293-8y2iaqnl 37 16 case case NN cord-308293-8y2iaqnl 37 17 series series NN cord-308293-8y2iaqnl 37 18 Mortality mortality NN cord-308293-8y2iaqnl 37 19 from from IN cord-308293-8y2iaqnl 37 20 Covid-19 Covid-19 NNP cord-308293-8y2iaqnl 37 21 Increases Increases NNPS cord-308293-8y2iaqnl 37 22 with with IN cord-308293-8y2iaqnl 37 23 Unsaturated Unsaturated NNP cord-308293-8y2iaqnl 37 24 Fat Fat NNP cord-308293-8y2iaqnl 37 25 , , , cord-308293-8y2iaqnl 37 26 and and CC cord-308293-8y2iaqnl 38 1 May May MD cord-308293-8y2iaqnl 38 2 Be be VB cord-308293-8y2iaqnl 38 3 Reduced reduce VBN cord-308293-8y2iaqnl 38 4 by by IN cord-308293-8y2iaqnl 38 5 Early early JJ cord-308293-8y2iaqnl 38 6 Calcium Calcium NNP cord-308293-8y2iaqnl 38 7 and and CC cord-308293-8y2iaqnl 38 8 Albumin Albumin NNP cord-308293-8y2iaqnl 38 9 Supplementation Supplementation NNP cord-308293-8y2iaqnl 39 1 Binding bind VBG cord-308293-8y2iaqnl 39 2 insight insight NN cord-308293-8y2iaqnl 39 3 of of IN cord-308293-8y2iaqnl 39 4 clinically clinically RB cord-308293-8y2iaqnl 39 5 oriented orient VBN cord-308293-8y2iaqnl 39 6 drug drug NN cord-308293-8y2iaqnl 39 7 famotidine famotidine NN cord-308293-8y2iaqnl 39 8 with with IN cord-308293-8y2iaqnl 39 9 the the DT cord-308293-8y2iaqnl 39 10 identified identify VBN cord-308293-8y2iaqnl 39 11 potential potential JJ cord-308293-8y2iaqnl 39 12 target target NN cord-308293-8y2iaqnl 39 13 of of IN cord-308293-8y2iaqnl 39 14 SARS SARS NNP cord-308293-8y2iaqnl 39 15 - - HYPH cord-308293-8y2iaqnl 39 16 CoV-2 CoV-2 NNP cord-308293-8y2iaqnl 40 1 COVID-19 covid-19 LS cord-308293-8y2iaqnl 40 2 : : : cord-308293-8y2iaqnl 40 3 Famotidine Famotidine NNP cord-308293-8y2iaqnl 40 4 , , , cord-308293-8y2iaqnl 40 5 Histamine histamine NN cord-308293-8y2iaqnl 40 6 , , , cord-308293-8y2iaqnl 40 7 Mast Mast NNP cord-308293-8y2iaqnl 40 8 Cells Cells NNPS cord-308293-8y2iaqnl 40 9 , , , cord-308293-8y2iaqnl 40 10 and and CC cord-308293-8y2iaqnl 40 11 Mechanisms Mechanisms NNP cord-308293-8y2iaqnl 40 12 Broad Broad NNP cord-308293-8y2iaqnl 40 13 - - HYPH cord-308293-8y2iaqnl 40 14 spectrum spectrum NN cord-308293-8y2iaqnl 40 15 inhibition inhibition NN cord-308293-8y2iaqnl 40 16 of of IN cord-308293-8y2iaqnl 40 17 coronavirus coronavirus NN cord-308293-8y2iaqnl 40 18 main main JJ cord-308293-8y2iaqnl 40 19 and and CC cord-308293-8y2iaqnl 40 20 papain papain NN cord-308293-8y2iaqnl 40 21 - - HYPH cord-308293-8y2iaqnl 40 22 like like JJ cord-308293-8y2iaqnl 40 23 proteases protease NNS cord-308293-8y2iaqnl 40 24 by by IN cord-308293-8y2iaqnl 40 25 HCV HCV NNP cord-308293-8y2iaqnl 40 26 drugs drug NNS