id sid tid token lemma pos cord-306495-o0ah1gj9 1 1 key key JJ cord-306495-o0ah1gj9 1 2 : : : cord-306495-o0ah1gj9 1 3 cord-306495-o0ah1gj9 cord-306495-o0ah1gj9 JJ cord-306495-o0ah1gj9 1 4 authors author NNS cord-306495-o0ah1gj9 1 5 : : : cord-306495-o0ah1gj9 1 6 Haidar Haidar NNP cord-306495-o0ah1gj9 1 7 , , , cord-306495-o0ah1gj9 1 8 Ghady Ghady NNP cord-306495-o0ah1gj9 1 9 title title NN cord-306495-o0ah1gj9 1 10 : : : cord-306495-o0ah1gj9 1 11 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 1 12 , , , cord-306495-o0ah1gj9 1 13 organ organ NN cord-306495-o0ah1gj9 1 14 transplantation transplantation NN cord-306495-o0ah1gj9 1 15 , , , cord-306495-o0ah1gj9 1 16 and and CC cord-306495-o0ah1gj9 1 17 the the DT cord-306495-o0ah1gj9 1 18 nuances nuance NNS cord-306495-o0ah1gj9 1 19 of of IN cord-306495-o0ah1gj9 1 20 immunomodulation immunomodulation NN cord-306495-o0ah1gj9 1 21 : : : cord-306495-o0ah1gj9 1 22 lessons lesson NNS cord-306495-o0ah1gj9 1 23 learned learn VBN cord-306495-o0ah1gj9 1 24 and and CC cord-306495-o0ah1gj9 1 25 what what WP cord-306495-o0ah1gj9 1 26 comes come VBZ cord-306495-o0ah1gj9 1 27 next next JJ cord-306495-o0ah1gj9 1 28 date date NN cord-306495-o0ah1gj9 1 29 : : : cord-306495-o0ah1gj9 1 30 2020 2020 CD cord-306495-o0ah1gj9 1 31 - - HYPH cord-306495-o0ah1gj9 1 32 08 08 CD cord-306495-o0ah1gj9 1 33 - - HYPH cord-306495-o0ah1gj9 1 34 11 11 CD cord-306495-o0ah1gj9 1 35 journal journal NN cord-306495-o0ah1gj9 1 36 : : : cord-306495-o0ah1gj9 2 1 Clin Clin NNP cord-306495-o0ah1gj9 2 2 Infect infect VB cord-306495-o0ah1gj9 2 3 Dis Dis NNP cord-306495-o0ah1gj9 2 4 DOI doi NN cord-306495-o0ah1gj9 2 5 : : : cord-306495-o0ah1gj9 2 6 10.1093 10.1093 CD cord-306495-o0ah1gj9 2 7 / / SYM cord-306495-o0ah1gj9 2 8 cid cid NN cord-306495-o0ah1gj9 2 9 / / SYM cord-306495-o0ah1gj9 2 10 ciaa1193 ciaa1193 NNP cord-306495-o0ah1gj9 2 11 sha sha NNP cord-306495-o0ah1gj9 2 12 : : : cord-306495-o0ah1gj9 2 13 0e5ae310fe5d10b94ccb81863294a855934fab93 0e5ae310fe5d10b94ccb81863294a855934fab93 CD cord-306495-o0ah1gj9 2 14 doc_id doc_id CD cord-306495-o0ah1gj9 2 15 : : : cord-306495-o0ah1gj9 2 16 306495 306495 CD cord-306495-o0ah1gj9 2 17 cord_uid cord_uid NNS cord-306495-o0ah1gj9 2 18 : : : cord-306495-o0ah1gj9 3 1 o0ah1gj9 o0ah1gj9 NNP cord-306495-o0ah1gj9 3 2 nan nan NNP cord-306495-o0ah1gj9 3 3 M M NNP cord-306495-o0ah1gj9 3 4 a a DT cord-306495-o0ah1gj9 4 1 n n CC cord-306495-o0ah1gj9 4 2 u u NNP cord-306495-o0ah1gj9 4 3 s s NNP cord-306495-o0ah1gj9 4 4 c c NN cord-306495-o0ah1gj9 4 5 r r NN cord-306495-o0ah1gj9 4 6 i i NN cord-306495-o0ah1gj9 4 7 p p NN cord-306495-o0ah1gj9 4 8 t t NN cord-306495-o0ah1gj9 4 9 2 2 CD cord-306495-o0ah1gj9 5 1 The the DT cord-306495-o0ah1gj9 5 2 coronavirus coronavirus NN cord-306495-o0ah1gj9 5 3 disease disease NN cord-306495-o0ah1gj9 5 4 2019 2019 CD cord-306495-o0ah1gj9 5 5 ( ( -LRB- cord-306495-o0ah1gj9 5 6 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 5 7 ) ) -RRB- cord-306495-o0ah1gj9 5 8 pandemic pandemic NN cord-306495-o0ah1gj9 5 9 has have VBZ cord-306495-o0ah1gj9 5 10 caused cause VBN cord-306495-o0ah1gj9 5 11 a a DT cord-306495-o0ah1gj9 5 12 seismic seismic JJ cord-306495-o0ah1gj9 5 13 shift shift NN cord-306495-o0ah1gj9 5 14 in in IN cord-306495-o0ah1gj9 5 15 transplant transplant NN cord-306495-o0ah1gj9 5 16 practices practice NNS cord-306495-o0ah1gj9 5 17 . . . cord-306495-o0ah1gj9 6 1 Many many JJ cord-306495-o0ah1gj9 6 2 centers center NNS cord-306495-o0ah1gj9 6 3 have have VBP cord-306495-o0ah1gj9 6 4 suspended suspend VBN cord-306495-o0ah1gj9 6 5 live live JJ cord-306495-o0ah1gj9 6 6 donor donor NN cord-306495-o0ah1gj9 6 7 transplants transplant NNS cord-306495-o0ah1gj9 6 8 , , , cord-306495-o0ah1gj9 6 9 and and CC cord-306495-o0ah1gj9 6 10 most most JJS cord-306495-o0ah1gj9 6 11 have have VBP cord-306495-o0ah1gj9 6 12 enforced enforce VBN cord-306495-o0ah1gj9 6 13 significant significant JJ cord-306495-o0ah1gj9 6 14 restrictions restriction NNS cord-306495-o0ah1gj9 6 15 to to IN cord-306495-o0ah1gj9 6 16 their -PRON- PRP$ cord-306495-o0ah1gj9 6 17 deceased deceased JJ cord-306495-o0ah1gj9 6 18 donor donor NN cord-306495-o0ah1gj9 6 19 programs program NNS cord-306495-o0ah1gj9 6 20 [ [ -LRB- cord-306495-o0ah1gj9 6 21 1 1 CD cord-306495-o0ah1gj9 6 22 ] ] -RRB- cord-306495-o0ah1gj9 6 23 . . . cord-306495-o0ah1gj9 7 1 Because because IN cord-306495-o0ah1gj9 7 2 of of IN cord-306495-o0ah1gj9 7 3 early early JJ cord-306495-o0ah1gj9 7 4 observations observation NNS cord-306495-o0ah1gj9 7 5 suggesting suggest VBG cord-306495-o0ah1gj9 7 6 a a DT cord-306495-o0ah1gj9 7 7 role role NN cord-306495-o0ah1gj9 7 8 of of IN cord-306495-o0ah1gj9 7 9 proinflammatory proinflammatory JJ cord-306495-o0ah1gj9 7 10 cytokines cytokine NNS cord-306495-o0ah1gj9 7 11 in in IN cord-306495-o0ah1gj9 7 12 the the DT cord-306495-o0ah1gj9 7 13 pathogenesis pathogenesis NN cord-306495-o0ah1gj9 7 14 of of IN cord-306495-o0ah1gj9 7 15 severe severe JJ cord-306495-o0ah1gj9 7 16 COVID-19 covid-19 JJ cord-306495-o0ah1gj9 7 17 [ [ -LRB- cord-306495-o0ah1gj9 7 18 2 2 CD cord-306495-o0ah1gj9 7 19 ] ] -RRB- cord-306495-o0ah1gj9 7 20 , , , cord-306495-o0ah1gj9 7 21 a a DT cord-306495-o0ah1gj9 7 22 prevailing prevail VBG cord-306495-o0ah1gj9 7 23 thought thought NN cord-306495-o0ah1gj9 7 24 has have VBZ cord-306495-o0ah1gj9 7 25 been be VBN cord-306495-o0ah1gj9 7 26 that that IN cord-306495-o0ah1gj9 7 27 the the DT cord-306495-o0ah1gj9 7 28 anti anti JJ cord-306495-o0ah1gj9 7 29 - - JJ cord-306495-o0ah1gj9 7 30 inflammatory inflammatory JJ cord-306495-o0ah1gj9 7 31 effects effect NNS cord-306495-o0ah1gj9 7 32 of of IN cord-306495-o0ah1gj9 7 33 immunosuppressive immunosuppressive JJ cord-306495-o0ah1gj9 7 34 medications medication NNS cord-306495-o0ah1gj9 7 35 may may MD cord-306495-o0ah1gj9 7 36 paradoxically paradoxically RB cord-306495-o0ah1gj9 7 37 diminish diminish VB cord-306495-o0ah1gj9 7 38 disease disease NN cord-306495-o0ah1gj9 7 39 severity severity NN cord-306495-o0ah1gj9 7 40 in in IN cord-306495-o0ah1gj9 7 41 solid solid JJ cord-306495-o0ah1gj9 7 42 organ organ NN cord-306495-o0ah1gj9 7 43 transplant transplant NN cord-306495-o0ah1gj9 7 44 ( ( -LRB- cord-306495-o0ah1gj9 7 45 SOT SOT NNP cord-306495-o0ah1gj9 7 46 ) ) -RRB- cord-306495-o0ah1gj9 7 47 recipients recipient NNS cord-306495-o0ah1gj9 7 48 with with IN cord-306495-o0ah1gj9 7 49 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 7 50 . . . cord-306495-o0ah1gj9 8 1 There there EX cord-306495-o0ah1gj9 8 2 is be VBZ cord-306495-o0ah1gj9 8 3 precedent precedent NN cord-306495-o0ah1gj9 8 4 in in IN cord-306495-o0ah1gj9 8 5 the the DT cord-306495-o0ah1gj9 8 6 literature literature NN cord-306495-o0ah1gj9 8 7 to to TO cord-306495-o0ah1gj9 8 8 support support VB cord-306495-o0ah1gj9 8 9 this this DT cord-306495-o0ah1gj9 8 10 line line NN cord-306495-o0ah1gj9 8 11 of of IN cord-306495-o0ah1gj9 8 12 speculation speculation NN cord-306495-o0ah1gj9 8 13 . . . cord-306495-o0ah1gj9 9 1 For for IN cord-306495-o0ah1gj9 9 2 instance instance NN cord-306495-o0ah1gj9 9 3 , , , cord-306495-o0ah1gj9 9 4 kidney kidney NN cord-306495-o0ah1gj9 9 5 and and CC cord-306495-o0ah1gj9 9 6 liver liver NN cord-306495-o0ah1gj9 9 7 transplant transplant NN cord-306495-o0ah1gj9 9 8 recipients recipient NNS cord-306495-o0ah1gj9 9 9 with with IN cord-306495-o0ah1gj9 9 10 sepsis sepsis NN cord-306495-o0ah1gj9 9 11 were be VBD cord-306495-o0ah1gj9 9 12 shown show VBN cord-306495-o0ah1gj9 9 13 to to TO cord-306495-o0ah1gj9 9 14 have have VB cord-306495-o0ah1gj9 9 15 lower low JJR cord-306495-o0ah1gj9 9 16 mortality mortality NN cord-306495-o0ah1gj9 9 17 rates rate NNS cord-306495-o0ah1gj9 9 18 compared compare VBN cord-306495-o0ah1gj9 9 19 to to IN cord-306495-o0ah1gj9 9 20 non non JJ cord-306495-o0ah1gj9 9 21 - - JJ cord-306495-o0ah1gj9 9 22 transplant transplant JJ cord-306495-o0ah1gj9 9 23 patients patient NNS cord-306495-o0ah1gj9 9 24 [ [ -LRB- cord-306495-o0ah1gj9 9 25 3 3 CD cord-306495-o0ah1gj9 9 26 ] ] -RRB- cord-306495-o0ah1gj9 9 27 , , , cord-306495-o0ah1gj9 9 28 which which WDT cord-306495-o0ah1gj9 9 29 was be VBD cord-306495-o0ah1gj9 9 30 thought think VBN cord-306495-o0ah1gj9 9 31 be be VB cord-306495-o0ah1gj9 9 32 partially partially RB cord-306495-o0ah1gj9 9 33 due due JJ cord-306495-o0ah1gj9 9 34 to to IN cord-306495-o0ah1gj9 9 35 a a DT cord-306495-o0ah1gj9 9 36 dampening dampening NN cord-306495-o0ah1gj9 9 37 of of IN cord-306495-o0ah1gj9 9 38 the the DT cord-306495-o0ah1gj9 9 39 destructive destructive JJ cord-306495-o0ah1gj9 9 40 aspects aspect NNS cord-306495-o0ah1gj9 9 41 of of IN cord-306495-o0ah1gj9 9 42 sepsis sepsis NN cord-306495-o0ah1gj9 9 43 by by IN cord-306495-o0ah1gj9 9 44 immunosuppressive immunosuppressive JJ cord-306495-o0ah1gj9 9 45 agents agent NNS cord-306495-o0ah1gj9 9 46 . . . cord-306495-o0ah1gj9 10 1 Additionally additionally RB cord-306495-o0ah1gj9 10 2 , , , cord-306495-o0ah1gj9 10 3 calcineurin calcineurin NN cord-306495-o0ah1gj9 10 4 inhibitors inhibitor NNS cord-306495-o0ah1gj9 10 5 modulate modulate VBP cord-306495-o0ah1gj9 10 6 the the DT cord-306495-o0ah1gj9 10 7 expression expression NN cord-306495-o0ah1gj9 10 8 of of IN cord-306495-o0ah1gj9 10 9 opportunistic opportunistic JJ cord-306495-o0ah1gj9 10 10 infections infection NNS cord-306495-o0ah1gj9 10 11 such such JJ cord-306495-o0ah1gj9 10 12 as as IN cord-306495-o0ah1gj9 10 13 cryptococcosis cryptococcosis NN cord-306495-o0ah1gj9 10 14 , , , cord-306495-o0ah1gj9 10 15 protecting protect VBG cord-306495-o0ah1gj9 10 16 against against IN cord-306495-o0ah1gj9 10 17 mortality mortality NN cord-306495-o0ah1gj9 10 18 in in IN cord-306495-o0ah1gj9 10 19 SOT SOT NNP cord-306495-o0ah1gj9 10 20 recipients recipient NNS cord-306495-o0ah1gj9 10 21 [ [ -LRB- cord-306495-o0ah1gj9 10 22 4 4 CD cord-306495-o0ah1gj9 10 23 ] ] -RRB- cord-306495-o0ah1gj9 10 24 . . . cord-306495-o0ah1gj9 11 1 However however RB cord-306495-o0ah1gj9 11 2 , , , cord-306495-o0ah1gj9 11 3 these these DT cord-306495-o0ah1gj9 11 4 optimistic optimistic JJ cord-306495-o0ah1gj9 11 5 notions notion NNS cord-306495-o0ah1gj9 11 6 were be VBD cord-306495-o0ah1gj9 11 7 at at IN cord-306495-o0ah1gj9 11 8 odds odd NNS cord-306495-o0ah1gj9 11 9 with with IN cord-306495-o0ah1gj9 11 10 our -PRON- PRP$ cord-306495-o0ah1gj9 11 11 knowledge knowledge NN cord-306495-o0ah1gj9 11 12 that that WDT cord-306495-o0ah1gj9 11 13 SOT SOT NNP cord-306495-o0ah1gj9 11 14 recipients recipient NNS cord-306495-o0ah1gj9 11 15 with with IN cord-306495-o0ah1gj9 11 16 respiratory respiratory JJ cord-306495-o0ah1gj9 11 17 viral viral JJ cord-306495-o0ah1gj9 11 18 infections infection NNS cord-306495-o0ah1gj9 11 19 such such JJ cord-306495-o0ah1gj9 11 20 as as IN cord-306495-o0ah1gj9 11 21 influenza influenza NN cord-306495-o0ah1gj9 11 22 develop develop VB cord-306495-o0ah1gj9 11 23 more more RBR cord-306495-o0ah1gj9 11 24 severe severe JJ cord-306495-o0ah1gj9 11 25 complications complication NNS cord-306495-o0ah1gj9 11 26 than than IN cord-306495-o0ah1gj9 11 27 the the DT cord-306495-o0ah1gj9 11 28 general general JJ cord-306495-o0ah1gj9 11 29 population population NN cord-306495-o0ah1gj9 11 30 . . . cord-306495-o0ah1gj9 12 1 Additionally additionally RB cord-306495-o0ah1gj9 12 2 , , , cord-306495-o0ah1gj9 12 3 transplant transplant NN cord-306495-o0ah1gj9 12 4 patients patient NNS cord-306495-o0ah1gj9 12 5 frequently frequently RB cord-306495-o0ah1gj9 12 6 suffer suffer VBP cord-306495-o0ah1gj9 12 7 from from IN cord-306495-o0ah1gj9 12 8 the the DT cord-306495-o0ah1gj9 12 9 same same JJ cord-306495-o0ah1gj9 12 10 comorbidities comorbiditie NNS cord-306495-o0ah1gj9 12 11 that that WDT cord-306495-o0ah1gj9 12 12 have have VBP cord-306495-o0ah1gj9 12 13 been be VBN cord-306495-o0ah1gj9 12 14 associated associate VBN cord-306495-o0ah1gj9 12 15 with with IN cord-306495-o0ah1gj9 12 16 detrimental detrimental JJ cord-306495-o0ah1gj9 12 17 outcomes outcome NNS cord-306495-o0ah1gj9 12 18 in in IN cord-306495-o0ah1gj9 12 19 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 12 20 . . . cord-306495-o0ah1gj9 13 1 Nonetheless nonetheless RB cord-306495-o0ah1gj9 13 2 , , , cord-306495-o0ah1gj9 13 3 and and CC cord-306495-o0ah1gj9 13 4 despite despite IN cord-306495-o0ah1gj9 13 5 early early JJ cord-306495-o0ah1gj9 13 6 hints hint NNS cord-306495-o0ah1gj9 13 7 that that IN cord-306495-o0ah1gj9 13 8 mortality mortality NN cord-306495-o0ah1gj9 13 9 in in IN cord-306495-o0ah1gj9 13 10 SOT SOT NNP cord-306495-o0ah1gj9 13 11 recipients recipient NNS cord-306495-o0ah1gj9 13 12 may may MD cord-306495-o0ah1gj9 13 13 be be VB cord-306495-o0ah1gj9 13 14 high high JJ cord-306495-o0ah1gj9 13 15 , , , cord-306495-o0ah1gj9 13 16 the the DT cord-306495-o0ah1gj9 13 17 outcomes outcome NNS cord-306495-o0ah1gj9 13 18 of of IN cord-306495-o0ah1gj9 13 19 SOT SOT NNP cord-306495-o0ah1gj9 13 20 recipients recipient NNS cord-306495-o0ah1gj9 13 21 with with IN cord-306495-o0ah1gj9 13 22 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 13 23 have have VBP cord-306495-o0ah1gj9 13 24 remained remain VBN cord-306495-o0ah1gj9 13 25 ill ill RB cord-306495-o0ah1gj9 13 26 - - HYPH cord-306495-o0ah1gj9 13 27 defined define VBN cord-306495-o0ah1gj9 13 28 . . . cord-306495-o0ah1gj9 14 1 In in IN cord-306495-o0ah1gj9 14 2 this this DT cord-306495-o0ah1gj9 14 3 issue issue NN cord-306495-o0ah1gj9 14 4 of of IN cord-306495-o0ah1gj9 14 5 the the DT cord-306495-o0ah1gj9 14 6 journal journal NN cord-306495-o0ah1gj9 14 7 , , , cord-306495-o0ah1gj9 14 8 Kates Kates NNP cord-306495-o0ah1gj9 14 9 and and CC cord-306495-o0ah1gj9 14 10 colleagues colleague NNS cord-306495-o0ah1gj9 14 11 describe describe VBP cord-306495-o0ah1gj9 14 12 the the DT cord-306495-o0ah1gj9 14 13 outcomes outcome NNS cord-306495-o0ah1gj9 14 14 of of IN cord-306495-o0ah1gj9 14 15 482 482 CD cord-306495-o0ah1gj9 14 16 SOT SOT NNP cord-306495-o0ah1gj9 14 17 recipients recipient NNS cord-306495-o0ah1gj9 14 18 with with IN cord-306495-o0ah1gj9 14 19 COVID-19 covid-19 CD cord-306495-o0ah1gj9 14 20 across across IN cord-306495-o0ah1gj9 14 21 over over IN cord-306495-o0ah1gj9 14 22 50 50 CD cord-306495-o0ah1gj9 14 23 transplant transplant NN cord-306495-o0ah1gj9 14 24 centers center NNS cord-306495-o0ah1gj9 14 25 . . . cord-306495-o0ah1gj9 15 1 While while IN cord-306495-o0ah1gj9 15 2 the the DT cord-306495-o0ah1gj9 15 3 majority majority NN cord-306495-o0ah1gj9 15 4 of of IN cord-306495-o0ah1gj9 15 5 patients patient NNS cord-306495-o0ah1gj9 15 6 were be VBD cord-306495-o0ah1gj9 15 7 kidney kidney NN cord-306495-o0ah1gj9 15 8 transplant transplant NN cord-306495-o0ah1gj9 15 9 recipients recipient NNS cord-306495-o0ah1gj9 15 10 , , , cord-306495-o0ah1gj9 15 11 this this DT cord-306495-o0ah1gj9 15 12 is be VBZ cord-306495-o0ah1gj9 15 13 nonetheless nonetheless RB cord-306495-o0ah1gj9 15 14 the the DT cord-306495-o0ah1gj9 15 15 largest large JJS cord-306495-o0ah1gj9 15 16 study study NN cord-306495-o0ah1gj9 15 17 of of IN cord-306495-o0ah1gj9 15 18 SOT SOT NNP cord-306495-o0ah1gj9 15 19 and and CC cord-306495-o0ah1gj9 15 20 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 15 21 to to IN cord-306495-o0ah1gj9 15 22 date date NN cord-306495-o0ah1gj9 15 23 and and CC cord-306495-o0ah1gj9 15 24 confirms confirm VBZ cord-306495-o0ah1gj9 15 25 the the DT cord-306495-o0ah1gj9 15 26 ominous ominous JJ cord-306495-o0ah1gj9 15 27 findings finding NNS cord-306495-o0ah1gj9 15 28 from from IN cord-306495-o0ah1gj9 15 29 smaller small JJR cord-306495-o0ah1gj9 15 30 cohorts cohort NNS cord-306495-o0ah1gj9 15 31 : : : cord-306495-o0ah1gj9 15 32 in in IN cord-306495-o0ah1gj9 15 33 short short JJ cord-306495-o0ah1gj9 15 34 , , , cord-306495-o0ah1gj9 15 35 SOT SOT NNP cord-306495-o0ah1gj9 15 36 recipients recipient NNS cord-306495-o0ah1gj9 15 37 with with IN cord-306495-o0ah1gj9 15 38 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 15 39 are be VBP cord-306495-o0ah1gj9 15 40 at at IN cord-306495-o0ah1gj9 15 41 high high JJ cord-306495-o0ah1gj9 15 42 risk risk NN cord-306495-o0ah1gj9 15 43 for for IN cord-306495-o0ah1gj9 15 44 complications complication NNS cord-306495-o0ah1gj9 15 45 and and CC cord-306495-o0ah1gj9 15 46 death death NN cord-306495-o0ah1gj9 15 47 . . . cord-306495-o0ah1gj9 16 1 The the DT cord-306495-o0ah1gj9 16 2 authors author NNS cord-306495-o0ah1gj9 16 3 demonstrate demonstrate VBP cord-306495-o0ah1gj9 16 4 that that IN cord-306495-o0ah1gj9 16 5 78 78 CD cord-306495-o0ah1gj9 16 6 % % NN cord-306495-o0ah1gj9 16 7 , , , cord-306495-o0ah1gj9 16 8 34 34 CD cord-306495-o0ah1gj9 16 9 % % NN cord-306495-o0ah1gj9 16 10 , , , cord-306495-o0ah1gj9 16 11 and and CC cord-306495-o0ah1gj9 16 12 27 27 CD cord-306495-o0ah1gj9 16 13 % % NN cord-306495-o0ah1gj9 16 14 of of IN cord-306495-o0ah1gj9 16 15 SOT SOT NNP cord-306495-o0ah1gj9 16 16 recipients recipient NNS cord-306495-o0ah1gj9 16 17 with with IN cord-306495-o0ah1gj9 16 18 COVID-19 covid-19 DT cord-306495-o0ah1gj9 16 19 require require JJ cord-306495-o0ah1gj9 16 20 hospitalization hospitalization NN cord-306495-o0ah1gj9 16 21 , , , cord-306495-o0ah1gj9 16 22 intensive intensive JJ cord-306495-o0ah1gj9 16 23 care care NN cord-306495-o0ah1gj9 16 24 , , , cord-306495-o0ah1gj9 16 25 and and CC cord-306495-o0ah1gj9 16 26 mechanical mechanical JJ cord-306495-o0ah1gj9 16 27 ventilation ventilation NN cord-306495-o0ah1gj9 16 28 , , , cord-306495-o0ah1gj9 16 29 respectively respectively RB cord-306495-o0ah1gj9 16 30 . . . cord-306495-o0ah1gj9 17 1 Additionally additionally RB cord-306495-o0ah1gj9 17 2 , , , cord-306495-o0ah1gj9 17 3 the the DT cord-306495-o0ah1gj9 17 4 inpatient inpatient JJ cord-306495-o0ah1gj9 17 5 mortality mortality NN cord-306495-o0ah1gj9 17 6 rate rate NN cord-306495-o0ah1gj9 17 7 was be VBD cord-306495-o0ah1gj9 17 8 ~20 ~20 NFP cord-306495-o0ah1gj9 17 9 % % NN cord-306495-o0ah1gj9 17 10 , , , cord-306495-o0ah1gj9 17 11 which which WDT cord-306495-o0ah1gj9 17 12 is be VBZ cord-306495-o0ah1gj9 17 13 similar similar JJ cord-306495-o0ah1gj9 17 14 to to IN cord-306495-o0ah1gj9 17 15 the the DT cord-306495-o0ah1gj9 17 16 pooled pool VBN cord-306495-o0ah1gj9 17 17 weighed weigh VBN cord-306495-o0ah1gj9 17 18 mortality mortality NN cord-306495-o0ah1gj9 17 19 rate rate NN cord-306495-o0ah1gj9 17 20 of of IN cord-306495-o0ah1gj9 17 21 ~19 ~19 CD cord-306495-o0ah1gj9 17 22 % % NN cord-306495-o0ah1gj9 18 1 ( ( -LRB- cord-306495-o0ah1gj9 18 2 range range NNP cord-306495-o0ah1gj9 18 3 8 8 CD cord-306495-o0ah1gj9 18 4 - - SYM cord-306495-o0ah1gj9 18 5 33 33 CD cord-306495-o0ah1gj9 18 6 % % NN cord-306495-o0ah1gj9 18 7 ) ) -RRB- cord-306495-o0ah1gj9 18 8 reported report VBD cord-306495-o0ah1gj9 18 9 in in IN cord-306495-o0ah1gj9 18 10 studies study NNS cord-306495-o0ah1gj9 18 11 from from IN cord-306495-o0ah1gj9 18 12 the the DT cord-306495-o0ah1gj9 18 13 general general JJ cord-306495-o0ah1gj9 18 14 population population NN cord-306495-o0ah1gj9 18 15 with with IN cord-306495-o0ah1gj9 18 16 a a DT cord-306495-o0ah1gj9 18 17 similar similar JJ cord-306495-o0ah1gj9 18 18 median median NN cord-306495-o0ah1gj9 18 19 age age NN cord-306495-o0ah1gj9 18 20 and and CC cord-306495-o0ah1gj9 18 21 prevalence prevalence NN cord-306495-o0ah1gj9 18 22 of of IN cord-306495-o0ah1gj9 18 23 comorbidities comorbiditie NNS cord-306495-o0ah1gj9 18 24 . . . cord-306495-o0ah1gj9 19 1 Indeed indeed RB cord-306495-o0ah1gj9 19 2 , , , cord-306495-o0ah1gj9 19 3 over over IN cord-306495-o0ah1gj9 19 4 90 90 CD cord-306495-o0ah1gj9 19 5 % % NN cord-306495-o0ah1gj9 19 6 of of IN cord-306495-o0ah1gj9 19 7 SOT SOT NNP cord-306495-o0ah1gj9 19 8 recipients recipient NNS cord-306495-o0ah1gj9 19 9 with with IN cord-306495-o0ah1gj9 19 10 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 19 11 had have VBD cord-306495-o0ah1gj9 19 12 chronic chronic JJ cord-306495-o0ah1gj9 19 13 medical medical JJ cord-306495-o0ah1gj9 19 14 conditions condition NNS cord-306495-o0ah1gj9 19 15 , , , cord-306495-o0ah1gj9 19 16 and and CC cord-306495-o0ah1gj9 19 17 nearly nearly RB cord-306495-o0ah1gj9 19 18 a a DT cord-306495-o0ah1gj9 19 19 third third JJ cord-306495-o0ah1gj9 19 20 were be VBD cord-306495-o0ah1gj9 19 21 over over IN cord-306495-o0ah1gj9 19 22 65 65 CD cord-306495-o0ah1gj9 19 23 years year NNS cord-306495-o0ah1gj9 19 24 of of IN cord-306495-o0ah1gj9 19 25 age age NN cord-306495-o0ah1gj9 19 26 . . . cord-306495-o0ah1gj9 20 1 The the DT cord-306495-o0ah1gj9 20 2 authors author NNS cord-306495-o0ah1gj9 20 3 should should MD cord-306495-o0ah1gj9 20 4 be be VB cord-306495-o0ah1gj9 20 5 commended commend VBN cord-306495-o0ah1gj9 20 6 for for IN cord-306495-o0ah1gj9 20 7 appropriately appropriately RB cord-306495-o0ah1gj9 20 8 navigating navigate VBG cord-306495-o0ah1gj9 20 9 the the DT cord-306495-o0ah1gj9 20 10 epidemiological epidemiological JJ cord-306495-o0ah1gj9 20 11 quagmire quagmire NN cord-306495-o0ah1gj9 20 12 of of IN cord-306495-o0ah1gj9 20 13 case case NN cord-306495-o0ah1gj9 20 14 fatality fatality NN cord-306495-o0ah1gj9 20 15 rates rate NNS cord-306495-o0ah1gj9 20 16 in in IN cord-306495-o0ah1gj9 20 17 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 20 18 , , , cord-306495-o0ah1gj9 20 19 as as IN cord-306495-o0ah1gj9 20 20 comparisons comparison NNS cord-306495-o0ah1gj9 20 21 with with IN cord-306495-o0ah1gj9 20 22 studies study NNS cord-306495-o0ah1gj9 20 23 of of IN cord-306495-o0ah1gj9 20 24 younger young JJR cord-306495-o0ah1gj9 20 25 and and CC cord-306495-o0ah1gj9 20 26 healthier healthy JJR cord-306495-o0ah1gj9 20 27 patients patient NNS cord-306495-o0ah1gj9 20 28 - - , cord-306495-o0ah1gj9 20 29 such such JJ cord-306495-o0ah1gj9 20 30 as as IN cord-306495-o0ah1gj9 20 31 the the DT cord-306495-o0ah1gj9 20 32 Chinese Chinese NNP cord-306495-o0ah1gj9 20 33 Center Center NNP cord-306495-o0ah1gj9 20 34 for for IN cord-306495-o0ah1gj9 20 35 Disease Disease NNP cord-306495-o0ah1gj9 20 36 Control Control NNP cord-306495-o0ah1gj9 20 37 study study NN cord-306495-o0ah1gj9 20 38 which which WDT cord-306495-o0ah1gj9 20 39 reported report VBD cord-306495-o0ah1gj9 20 40 a a DT cord-306495-o0ah1gj9 20 41 mortality mortality NN cord-306495-o0ah1gj9 20 42 rate rate NN cord-306495-o0ah1gj9 20 43 of of IN cord-306495-o0ah1gj9 20 44 2.3%[5]-would 2.3%[5]-would NNP cord-306495-o0ah1gj9 20 45 not not RB cord-306495-o0ah1gj9 20 46 have have VBP cord-306495-o0ah1gj9 20 47 been be VBN cord-306495-o0ah1gj9 20 48 suitable suitable JJ cord-306495-o0ah1gj9 20 49 . . . cord-306495-o0ah1gj9 21 1 The the DT cord-306495-o0ah1gj9 21 2 only only JJ cord-306495-o0ah1gj9 21 3 predictors predictor NNS cord-306495-o0ah1gj9 21 4 of of IN cord-306495-o0ah1gj9 21 5 mortality mortality NN cord-306495-o0ah1gj9 21 6 in in IN cord-306495-o0ah1gj9 21 7 the the DT cord-306495-o0ah1gj9 21 8 current current JJ cord-306495-o0ah1gj9 21 9 study study NN cord-306495-o0ah1gj9 21 10 were be VBD cord-306495-o0ah1gj9 21 11 age age NN cord-306495-o0ah1gj9 21 12 ( ( -LRB- cord-306495-o0ah1gj9 21 13 > > NFP cord-306495-o0ah1gj9 21 14 65 65 CD cord-306495-o0ah1gj9 21 15 years year NNS cord-306495-o0ah1gj9 21 16 ) ) -RRB- cord-306495-o0ah1gj9 21 17 , , , cord-306495-o0ah1gj9 21 18 heart heart NN cord-306495-o0ah1gj9 21 19 failure failure NN cord-306495-o0ah1gj9 21 20 , , , cord-306495-o0ah1gj9 21 21 chronic chronic JJ cord-306495-o0ah1gj9 21 22 lung lung NN cord-306495-o0ah1gj9 21 23 disease disease NN cord-306495-o0ah1gj9 21 24 , , , cord-306495-o0ah1gj9 21 25 obesity obesity NN cord-306495-o0ah1gj9 21 26 , , , cord-306495-o0ah1gj9 21 27 pneumonia pneumonia NN cord-306495-o0ah1gj9 21 28 , , , cord-306495-o0ah1gj9 21 29 and and CC cord-306495-o0ah1gj9 21 30 lymphopenia lymphopenia NNP cord-306495-o0ah1gj9 21 31 . . . cord-306495-o0ah1gj9 22 1 In in IN cord-306495-o0ah1gj9 22 2 contrast contrast NN cord-306495-o0ah1gj9 22 3 , , , cord-306495-o0ah1gj9 22 4 the the DT cord-306495-o0ah1gj9 22 5 " " `` cord-306495-o0ah1gj9 22 6 net net JJ cord-306495-o0ah1gj9 22 7 state state NN cord-306495-o0ah1gj9 22 8 of of IN cord-306495-o0ah1gj9 22 9 immunosuppression immunosuppression NN cord-306495-o0ah1gj9 22 10 " " '' cord-306495-o0ah1gj9 22 11 had have VBD cord-306495-o0ah1gj9 22 12 no no DT cord-306495-o0ah1gj9 22 13 impact impact NN cord-306495-o0ah1gj9 22 14 on on IN cord-306495-o0ah1gj9 22 15 mortality mortality NN cord-306495-o0ah1gj9 22 16 , , , cord-306495-o0ah1gj9 22 17 neither neither CC cord-306495-o0ah1gj9 22 18 did do VBD cord-306495-o0ah1gj9 22 19 time time NN cord-306495-o0ah1gj9 22 20 from from IN cord-306495-o0ah1gj9 22 21 transplant transplant NN cord-306495-o0ah1gj9 22 22 . . . cord-306495-o0ah1gj9 23 1 Thus thus RB cord-306495-o0ah1gj9 23 2 , , , cord-306495-o0ah1gj9 23 3 while while IN cord-306495-o0ah1gj9 23 4 morbidity morbidity NN cord-306495-o0ah1gj9 23 5 and and CC cord-306495-o0ah1gj9 23 6 mortality mortality NN cord-306495-o0ah1gj9 23 7 related relate VBN cord-306495-o0ah1gj9 23 8 to to IN cord-306495-o0ah1gj9 23 9 COVID-19 covid-19 VB cord-306495-o0ah1gj9 23 10 in in IN cord-306495-o0ah1gj9 23 11 SOT SOT NNP cord-306495-o0ah1gj9 23 12 recipients recipient NNS cord-306495-o0ah1gj9 23 13 are be VBP cord-306495-o0ah1gj9 23 14 substantial substantial JJ cord-306495-o0ah1gj9 23 15 , , , cord-306495-o0ah1gj9 23 16 A a DT cord-306495-o0ah1gj9 23 17 c c NN cord-306495-o0ah1gj9 23 18 c c NN cord-306495-o0ah1gj9 23 19 e e NN cord-306495-o0ah1gj9 23 20 p p NN cord-306495-o0ah1gj9 23 21 t t NN cord-306495-o0ah1gj9 23 22 e e NN cord-306495-o0ah1gj9 23 23 d d NNP cord-306495-o0ah1gj9 23 24 M M NNP cord-306495-o0ah1gj9 23 25 a a NNP cord-306495-o0ah1gj9 23 26 n n NN cord-306495-o0ah1gj9 23 27 u u NNP cord-306495-o0ah1gj9 23 28 s s NNP cord-306495-o0ah1gj9 23 29 c c NN cord-306495-o0ah1gj9 23 30 r r NN cord-306495-o0ah1gj9 23 31 i i NN cord-306495-o0ah1gj9 23 32 p p NN cord-306495-o0ah1gj9 23 33 t t NN cord-306495-o0ah1gj9 23 34 3 3 CD cord-306495-o0ah1gj9 24 1 they -PRON- PRP cord-306495-o0ah1gj9 24 2 appear appear VBP cord-306495-o0ah1gj9 24 3 to to TO cord-306495-o0ah1gj9 24 4 be be VB cord-306495-o0ah1gj9 24 5 driven drive VBN cord-306495-o0ah1gj9 24 6 by by IN cord-306495-o0ah1gj9 24 7 age age NN cord-306495-o0ah1gj9 24 8 and and CC cord-306495-o0ah1gj9 24 9 underlying underlying JJ cord-306495-o0ah1gj9 24 10 medical medical JJ cord-306495-o0ah1gj9 24 11 conditions condition NNS cord-306495-o0ah1gj9 24 12 and and CC cord-306495-o0ah1gj9 24 13 unaffected unaffected JJ cord-306495-o0ah1gj9 24 14 by by IN cord-306495-o0ah1gj9 24 15 immunosuppression immunosuppression NN cord-306495-o0ah1gj9 24 16 , , , cord-306495-o0ah1gj9 24 17 corroborating corroborate VBG cord-306495-o0ah1gj9 24 18 the the DT cord-306495-o0ah1gj9 24 19 results result NNS cord-306495-o0ah1gj9 24 20 of of IN cord-306495-o0ah1gj9 24 21 other other JJ cord-306495-o0ah1gj9 24 22 studies study NNS cord-306495-o0ah1gj9 24 23 in in IN cord-306495-o0ah1gj9 24 24 the the DT cord-306495-o0ah1gj9 24 25 general general JJ cord-306495-o0ah1gj9 24 26 population population NN cord-306495-o0ah1gj9 24 27 . . . cord-306495-o0ah1gj9 25 1 The the DT cord-306495-o0ah1gj9 25 2 study study NN cord-306495-o0ah1gj9 25 3 included include VBD cord-306495-o0ah1gj9 25 4 only only RB cord-306495-o0ah1gj9 25 5 30 30 CD cord-306495-o0ah1gj9 25 6 lung lung NN cord-306495-o0ah1gj9 25 7 transplant transplant NN cord-306495-o0ah1gj9 25 8 recipients recipient NNS cord-306495-o0ah1gj9 25 9 was be VBD cord-306495-o0ah1gj9 25 10 therefore therefore RB cord-306495-o0ah1gj9 25 11 unable unable JJ cord-306495-o0ah1gj9 25 12 to to TO cord-306495-o0ah1gj9 25 13 assess assess VB cord-306495-o0ah1gj9 25 14 whether whether IN cord-306495-o0ah1gj9 25 15 mortality mortality NN cord-306495-o0ah1gj9 25 16 in in IN cord-306495-o0ah1gj9 25 17 these these DT cord-306495-o0ah1gj9 25 18 patients patient NNS cord-306495-o0ah1gj9 25 19 is be VBZ cord-306495-o0ah1gj9 25 20 greatest great JJS cord-306495-o0ah1gj9 25 21 ( ( -LRB- cord-306495-o0ah1gj9 25 22 as as IN cord-306495-o0ah1gj9 25 23 is be VBZ cord-306495-o0ah1gj9 25 24 the the DT cord-306495-o0ah1gj9 25 25 case case NN cord-306495-o0ah1gj9 25 26 with with IN cord-306495-o0ah1gj9 25 27 sepsis sepsis NN cord-306495-o0ah1gj9 25 28 [ [ -LRB- cord-306495-o0ah1gj9 25 29 3 3 CD cord-306495-o0ah1gj9 25 30 ] ] -RRB- cord-306495-o0ah1gj9 25 31 ) ) -RRB- cord-306495-o0ah1gj9 25 32 , , , cord-306495-o0ah1gj9 25 33 or or CC cord-306495-o0ah1gj9 25 34 whether whether IN cord-306495-o0ah1gj9 25 35 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 25 36 precipitates precipitate VBZ cord-306495-o0ah1gj9 25 37 acute acute JJ cord-306495-o0ah1gj9 25 38 or or CC cord-306495-o0ah1gj9 25 39 chronic chronic JJ cord-306495-o0ah1gj9 25 40 lung lung NN cord-306495-o0ah1gj9 25 41 allograft allograft NN cord-306495-o0ah1gj9 25 42 rejection rejection NN cord-306495-o0ah1gj9 25 43 . . . cord-306495-o0ah1gj9 26 1 Furthermore furthermore RB cord-306495-o0ah1gj9 26 2 , , , cord-306495-o0ah1gj9 26 3 since since IN cord-306495-o0ah1gj9 26 4 all all DT cord-306495-o0ah1gj9 26 5 laboratory laboratory NN cord-306495-o0ah1gj9 26 6 testing testing NN cord-306495-o0ah1gj9 26 7 was be VBD cord-306495-o0ah1gj9 26 8 done do VBN cord-306495-o0ah1gj9 26 9 as as IN cord-306495-o0ah1gj9 26 10 standard standard NN cord-306495-o0ah1gj9 26 11 of of IN cord-306495-o0ah1gj9 26 12 care care NN cord-306495-o0ah1gj9 26 13 , , , cord-306495-o0ah1gj9 26 14 the the DT cord-306495-o0ah1gj9 26 15 study study NN cord-306495-o0ah1gj9 26 16 could could MD cord-306495-o0ah1gj9 26 17 not not RB cord-306495-o0ah1gj9 26 18 evaluate evaluate VB cord-306495-o0ah1gj9 26 19 severe severe JJ cord-306495-o0ah1gj9 26 20 acute acute JJ cord-306495-o0ah1gj9 26 21 respiratory respiratory JJ cord-306495-o0ah1gj9 26 22 syndrome syndrome NN cord-306495-o0ah1gj9 26 23 coronavirus coronavirus NN cord-306495-o0ah1gj9 26 24 2 2 CD cord-306495-o0ah1gj9 26 25 ( ( -LRB- cord-306495-o0ah1gj9 26 26 SARS SARS NNP cord-306495-o0ah1gj9 26 27 - - HYPH cord-306495-o0ah1gj9 26 28 CoV-2 CoV-2 NNP cord-306495-o0ah1gj9 26 29 ) ) -RRB- cord-306495-o0ah1gj9 26 30 viremia viremia NN cord-306495-o0ah1gj9 26 31 or or CC cord-306495-o0ah1gj9 26 32 the the DT cord-306495-o0ah1gj9 26 33 duration duration NN cord-306495-o0ah1gj9 26 34 of of IN cord-306495-o0ah1gj9 26 35 SARS SARS NNP cord-306495-o0ah1gj9 26 36 - - HYPH cord-306495-o0ah1gj9 26 37 CoV-2 CoV-2 NNP cord-306495-o0ah1gj9 26 38 PCR PCR NNP cord-306495-o0ah1gj9 26 39 positivity positivity NN cord-306495-o0ah1gj9 26 40 , , , cord-306495-o0ah1gj9 26 41 which which WDT cord-306495-o0ah1gj9 26 42 may may MD cord-306495-o0ah1gj9 26 43 be be VB cord-306495-o0ah1gj9 26 44 longer long JJR cord-306495-o0ah1gj9 26 45 than than IN cord-306495-o0ah1gj9 26 46 that that DT cord-306495-o0ah1gj9 26 47 of of IN cord-306495-o0ah1gj9 26 48 non non JJ cord-306495-o0ah1gj9 26 49 - - JJ cord-306495-o0ah1gj9 26 50 transplant transplant JJ cord-306495-o0ah1gj9 26 51 patients patient NNS cord-306495-o0ah1gj9 26 52 . . . cord-306495-o0ah1gj9 27 1 While while IN cord-306495-o0ah1gj9 27 2 prolonged prolong VBN cord-306495-o0ah1gj9 27 3 viral viral JJ cord-306495-o0ah1gj9 27 4 shedding shedding NN cord-306495-o0ah1gj9 27 5 is be VBZ cord-306495-o0ah1gj9 27 6 common common JJ cord-306495-o0ah1gj9 27 7 and and CC cord-306495-o0ah1gj9 27 8 does do VBZ cord-306495-o0ah1gj9 27 9 not not RB cord-306495-o0ah1gj9 27 10 imply imply VB cord-306495-o0ah1gj9 27 11 infectivity infectivity NN cord-306495-o0ah1gj9 27 12 [ [ -LRB- cord-306495-o0ah1gj9 27 13 6 6 CD cord-306495-o0ah1gj9 27 14 ] ] -RRB- cord-306495-o0ah1gj9 27 15 , , . cord-306495-o0ah1gj9 28 1 critically critically RB cord-306495-o0ah1gj9 28 2 ill ill JJ cord-306495-o0ah1gj9 28 3 SOT SOT NNP cord-306495-o0ah1gj9 28 4 recipients recipient NNS cord-306495-o0ah1gj9 28 5 who who WP cord-306495-o0ah1gj9 28 6 are be VBP cord-306495-o0ah1gj9 28 7 Indeed indeed RB cord-306495-o0ah1gj9 28 8 , , , cord-306495-o0ah1gj9 29 1 a a DT cord-306495-o0ah1gj9 29 2 recent recent JJ cord-306495-o0ah1gj9 29 3 study study NN cord-306495-o0ah1gj9 29 4 of of IN cord-306495-o0ah1gj9 29 5 deep deep JJ cord-306495-o0ah1gj9 29 6 immune immune JJ cord-306495-o0ah1gj9 29 7 profiling profiling NN cord-306495-o0ah1gj9 29 8 of of IN cord-306495-o0ah1gj9 29 9 patients patient NNS cord-306495-o0ah1gj9 29 10 with with IN cord-306495-o0ah1gj9 29 11 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 29 12 revealed reveal VBD cord-306495-o0ah1gj9 29 13 several several JJ cord-306495-o0ah1gj9 29 14 " " `` cord-306495-o0ah1gj9 29 15 immunotypes immunotype NNS cord-306495-o0ah1gj9 29 16 " " '' cord-306495-o0ah1gj9 29 17 ranging range VBG cord-306495-o0ah1gj9 29 18 from from IN cord-306495-o0ah1gj9 29 19 robust robust JJ cord-306495-o0ah1gj9 29 20 CD4 CD4 NNP cord-306495-o0ah1gj9 29 21 and/or and/or CC cord-306495-o0ah1gj9 29 22 CD8 CD8 NNP cord-306495-o0ah1gj9 29 23 responses response NNS cord-306495-o0ah1gj9 29 24 to to IN cord-306495-o0ah1gj9 29 25 minimal minimal JJ cord-306495-o0ah1gj9 29 26 lymphocyte lymphocyte NN cord-306495-o0ah1gj9 29 27 responses response NNS cord-306495-o0ah1gj9 29 28 to to IN cord-306495-o0ah1gj9 29 29 infection infection NN cord-306495-o0ah1gj9 29 30 [ [ -LRB- cord-306495-o0ah1gj9 29 31 8 8 CD cord-306495-o0ah1gj9 29 32 ] ] -RRB- cord-306495-o0ah1gj9 29 33 . . . cord-306495-o0ah1gj9 30 1 Furthermore furthermore RB cord-306495-o0ah1gj9 30 2 , , , cord-306495-o0ah1gj9 30 3 the the DT cord-306495-o0ah1gj9 30 4 mortality mortality NN cord-306495-o0ah1gj9 30 5 benefit benefit NN cord-306495-o0ah1gj9 30 6 of of IN cord-306495-o0ah1gj9 30 7 dexamethasone dexamethasone NN cord-306495-o0ah1gj9 30 8 among among IN cord-306495-o0ah1gj9 30 9 patients patient NNS cord-306495-o0ah1gj9 30 10 with with IN cord-306495-o0ah1gj9 30 11 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 30 12 who who WP cord-306495-o0ah1gj9 30 13 require require VBP cord-306495-o0ah1gj9 30 14 supplemental supplemental JJ cord-306495-o0ah1gj9 30 15 oxygen oxygen NN cord-306495-o0ah1gj9 30 16 , , , cord-306495-o0ah1gj9 30 17 particularly particularly RB cord-306495-o0ah1gj9 30 18 those those DT cord-306495-o0ah1gj9 30 19 who who WP cord-306495-o0ah1gj9 30 20 received receive VBD cord-306495-o0ah1gj9 30 21 the the DT cord-306495-o0ah1gj9 30 22 drug drug NN cord-306495-o0ah1gj9 30 23 after after IN cord-306495-o0ah1gj9 30 24 their -PRON- PRP$ cord-306495-o0ah1gj9 30 25 first first JJ cord-306495-o0ah1gj9 30 26 week week NN cord-306495-o0ah1gj9 30 27 of of IN cord-306495-o0ah1gj9 30 28 illness illness NN cord-306495-o0ah1gj9 30 29 [ [ -LRB- cord-306495-o0ah1gj9 30 30 9 9 CD cord-306495-o0ah1gj9 30 31 ] ] -RRB- cord-306495-o0ah1gj9 30 32 , , , cord-306495-o0ah1gj9 30 33 lends lend VBZ cord-306495-o0ah1gj9 30 34 some some DT cord-306495-o0ah1gj9 30 35 credence credence NN cord-306495-o0ah1gj9 30 36 to to IN cord-306495-o0ah1gj9 30 37 the the DT cord-306495-o0ah1gj9 30 38 notion notion NN cord-306495-o0ah1gj9 30 39 that that IN cord-306495-o0ah1gj9 30 40 Several several JJ cord-306495-o0ah1gj9 30 41 issues issue NNS cord-306495-o0ah1gj9 30 42 unique unique JJ cord-306495-o0ah1gj9 30 43 to to IN cord-306495-o0ah1gj9 30 44 transplantation transplantation NN cord-306495-o0ah1gj9 30 45 will will MD cord-306495-o0ah1gj9 30 46 require require VB cord-306495-o0ah1gj9 30 47 re re NN cord-306495-o0ah1gj9 30 48 - - NN cord-306495-o0ah1gj9 30 49 evaluation evaluation NN cord-306495-o0ah1gj9 30 50 as as IN cord-306495-o0ah1gj9 30 51 the the DT cord-306495-o0ah1gj9 30 52 pandemic pandemic NN cord-306495-o0ah1gj9 30 53 evolves evolve VBZ cord-306495-o0ah1gj9 30 54 . . . cord-306495-o0ah1gj9 31 1 First first RB cord-306495-o0ah1gj9 31 2 , , , cord-306495-o0ah1gj9 31 3 programs program NNS cord-306495-o0ah1gj9 31 4 need need VBP cord-306495-o0ah1gj9 31 5 to to TO cord-306495-o0ah1gj9 31 6 be be VB cord-306495-o0ah1gj9 31 7 flexible flexible JJ cord-306495-o0ah1gj9 31 8 in in IN cord-306495-o0ah1gj9 31 9 how how WRB cord-306495-o0ah1gj9 31 10 they -PRON- PRP cord-306495-o0ah1gj9 31 11 adapt adapt VBP cord-306495-o0ah1gj9 31 12 to to IN cord-306495-o0ah1gj9 31 13 rising rise VBG cord-306495-o0ah1gj9 31 14 cases case NNS cord-306495-o0ah1gj9 31 15 in in IN cord-306495-o0ah1gj9 31 16 their -PRON- PRP$ cord-306495-o0ah1gj9 31 17 regions region NNS cord-306495-o0ah1gj9 31 18 , , , cord-306495-o0ah1gj9 31 19 relying rely VBG cord-306495-o0ah1gj9 31 20 on on IN cord-306495-o0ah1gj9 31 21 a a DT cord-306495-o0ah1gj9 31 22 tiered tiered JJ cord-306495-o0ah1gj9 31 23 approach approach NN cord-306495-o0ah1gj9 31 24 for for IN cord-306495-o0ah1gj9 31 25 adjusting adjust VBG cord-306495-o0ah1gj9 31 26 transplant transplant NN cord-306495-o0ah1gj9 31 27 activity activity NN cord-306495-o0ah1gj9 31 28 based base VBN cord-306495-o0ah1gj9 31 29 on on IN cord-306495-o0ah1gj9 31 30 the the DT cord-306495-o0ah1gj9 31 31 burden burden NN cord-306495-o0ah1gj9 31 32 of of IN cord-306495-o0ah1gj9 31 33 COVID-19 covid-19 NN cord-306495-o0ah1gj9 31 34 in in IN cord-306495-o0ah1gj9 31 35 the the DT cord-306495-o0ah1gj9 31 36 region region NN cord-306495-o0ah1gj9 31 37 and and CC cord-306495-o0ah1gj9 31 38 hospital hospital NN cord-306495-o0ah1gj9 31 39 . . . cord-306495-o0ah1gj9 32 1 Moreover moreover RB cord-306495-o0ah1gj9 32 2 , , , cord-306495-o0ah1gj9 32 3 centers center NNS cord-306495-o0ah1gj9 32 4 that that WDT cord-306495-o0ah1gj9 32 5 have have VBP cord-306495-o0ah1gj9 32 6 remained remain VBN cord-306495-o0ah1gj9 32 7 unaffected unaffected JJ cord-306495-o0ah1gj9 32 8 by by IN cord-306495-o0ah1gj9 32 9 the the DT cord-306495-o0ah1gj9 32 10 pandemic pandemic NN cord-306495-o0ah1gj9 32 11 may may MD cord-306495-o0ah1gj9 32 12 need need VB cord-306495-o0ah1gj9 32 13 to to TO cord-306495-o0ah1gj9 32 14 resort resort VB cord-306495-o0ah1gj9 32 15 to to IN cord-306495-o0ah1gj9 32 16 temporary temporary JJ cord-306495-o0ah1gj9 32 17 cessation cessation NN cord-306495-o0ah1gj9 32 18 of of IN cord-306495-o0ah1gj9 32 19 transplants transplant NNS cord-306495-o0ah1gj9 32 20 if if IN cord-306495-o0ah1gj9 32 21 COVID-19 covid-19 JJ cord-306495-o0ah1gj9 32 22 cases case NNS cord-306495-o0ah1gj9 32 23 surge surge VBP cord-306495-o0ah1gj9 32 24 . . . cord-306495-o0ah1gj9 33 1 Second second RB cord-306495-o0ah1gj9 33 2 , , , cord-306495-o0ah1gj9 33 3 centers center NNS cord-306495-o0ah1gj9 33 4 performing perform VBG cord-306495-o0ah1gj9 33 5 pre pre JJ cord-306495-o0ah1gj9 33 6 - - JJ cord-306495-o0ah1gj9 33 7 operative operative JJ cord-306495-o0ah1gj9 33 8 SARS SARS NNP cord-306495-o0ah1gj9 33 9 - - HYPH cord-306495-o0ah1gj9 33 10 CoV-2 CoV-2 NNP cord-306495-o0ah1gj9 33 11 PCR PCR NNP cord-306495-o0ah1gj9 33 12 screening screening NN cord-306495-o0ah1gj9 33 13 for for IN cord-306495-o0ah1gj9 33 14 asymptomatic asymptomatic JJ cord-306495-o0ah1gj9 33 15 transplant transplant NN cord-306495-o0ah1gj9 33 16 candidates candidate NNS cord-306495-o0ah1gj9 33 17 must must MD cord-306495-o0ah1gj9 33 18 publish publish VB cord-306495-o0ah1gj9 33 19 their -PRON- PRP$ cord-306495-o0ah1gj9 33 20 experiences experience NNS cord-306495-o0ah1gj9 33 21 . . . cord-306495-o0ah1gj9 34 1 These these DT cord-306495-o0ah1gj9 34 2 studies study NNS cord-306495-o0ah1gj9 34 3 should should MD cord-306495-o0ah1gj9 34 4 focus focus VB cord-306495-o0ah1gj9 34 5 on on IN cord-306495-o0ah1gj9 34 6 the the DT cord-306495-o0ah1gj9 34 7 impact impact NN cord-306495-o0ah1gj9 34 8 that that WDT cord-306495-o0ah1gj9 34 9 cancelling cancel VBG cord-306495-o0ah1gj9 34 10 cases case NNS cord-306495-o0ah1gj9 34 11 due due JJ cord-306495-o0ah1gj9 34 12 to to IN cord-306495-o0ah1gj9 34 13 positive positive JJ cord-306495-o0ah1gj9 34 14 PCRs pcr NNS cord-306495-o0ah1gj9 34 15 has have VBZ cord-306495-o0ah1gj9 34 16 on on IN cord-306495-o0ah1gj9 34 17 waitlist waitlist NN cord-306495-o0ah1gj9 34 18 mortality mortality NN cord-306495-o0ah1gj9 34 19 , , , cord-306495-o0ah1gj9 34 20 and and CC cord-306495-o0ah1gj9 34 21 on on IN cord-306495-o0ah1gj9 34 22 the the DT cord-306495-o0ah1gj9 34 23 optimal optimal JJ cord-306495-o0ah1gj9 34 24 timing timing NN cord-306495-o0ah1gj9 34 25 of of IN cord-306495-o0ah1gj9 34 26 reactivating reactivate VBG cord-306495-o0ah1gj9 34 27 a a DT cord-306495-o0ah1gj9 34 28 SARS SARS NNP cord-306495-o0ah1gj9 34 29 - - HYPH cord-306495-o0ah1gj9 34 30 CoV-2-positive cov-2-positive JJ cord-306495-o0ah1gj9 34 31 transplant transplant NN cord-306495-o0ah1gj9 34 32 candidate candidate NN cord-306495-o0ah1gj9 34 33 . . . cord-306495-o0ah1gj9 35 1 Third third JJ cord-306495-o0ah1gj9 35 2 , , , cord-306495-o0ah1gj9 35 3 universal universal JJ cord-306495-o0ah1gj9 35 4 SARS SARS NNP cord-306495-o0ah1gj9 35 5 - - HYPH cord-306495-o0ah1gj9 35 6 CoV-2 CoV-2 NNP cord-306495-o0ah1gj9 35 7 testing testing NN cord-306495-o0ah1gj9 35 8 of of IN cord-306495-o0ah1gj9 35 9 deceased deceased JJ cord-306495-o0ah1gj9 35 10 donors donor NNS cord-306495-o0ah1gj9 35 11 , , , cord-306495-o0ah1gj9 35 12 which which WDT cord-306495-o0ah1gj9 35 13 is be VBZ cord-306495-o0ah1gj9 35 14 currently currently RB cord-306495-o0ah1gj9 35 15 recommended recommend VBN cord-306495-o0ah1gj9 35 16 by by IN cord-306495-o0ah1gj9 35 17 the the DT cord-306495-o0ah1gj9 35 18 AST[7 AST[7 NNP cord-306495-o0ah1gj9 35 19 ] ] -RRB- cord-306495-o0ah1gj9 35 20 , , , cord-306495-o0ah1gj9 35 21 may may MD cord-306495-o0ah1gj9 35 22 one one CD cord-306495-o0ah1gj9 35 23 day day NN cord-306495-o0ah1gj9 35 24 be be VB cord-306495-o0ah1gj9 35 25 relaxed relax VBN cord-306495-o0ah1gj9 35 26 as as IN cord-306495-o0ah1gj9 35 27 herd herd NN cord-306495-o0ah1gj9 35 28 immunity immunity NN cord-306495-o0ah1gj9 35 29 develops develop VBZ cord-306495-o0ah1gj9 35 30 and and CC cord-306495-o0ah1gj9 35 31 once once RB cord-306495-o0ah1gj9 35 32 SARS SARS NNP cord-306495-o0ah1gj9 35 33 - - HYPH cord-306495-o0ah1gj9 35 34 CoV-2 CoV-2 NNP cord-306495-o0ah1gj9 35 35 becomes become VBZ cord-306495-o0ah1gj9 35 36 seasonal seasonal JJ cord-306495-o0ah1gj9 35 37 circulating circulate VBG cord-306495-o0ah1gj9 35 38 virus virus NN cord-306495-o0ah1gj9 35 39 . . . cord-306495-o0ah1gj9 36 1 Finally finally RB cord-306495-o0ah1gj9 36 2 , , , cord-306495-o0ah1gj9 36 3 while while IN cord-306495-o0ah1gj9 36 4 it -PRON- PRP cord-306495-o0ah1gj9 36 5 is be VBZ cord-306495-o0ah1gj9 36 6 permissible permissible JJ cord-306495-o0ah1gj9 36 7 to to TO cord-306495-o0ah1gj9 36 8 use use VB cord-306495-o0ah1gj9 36 9 organs organ NNS cord-306495-o0ah1gj9 36 10 other other JJ cord-306495-o0ah1gj9 36 11 than than IN cord-306495-o0ah1gj9 36 12 lungs lung NNS cord-306495-o0ah1gj9 36 13 and and CC cord-306495-o0ah1gj9 36 14 intestines intestine NNS cord-306495-o0ah1gj9 36 15 from from IN cord-306495-o0ah1gj9 36 16 donors donor NNS cord-306495-o0ah1gj9 36 17 with with IN cord-306495-o0ah1gj9 36 18 influenza influenza NN cord-306495-o0ah1gj9 36 19 , , , cord-306495-o0ah1gj9 36 20 whether whether IN cord-306495-o0ah1gj9 36 21 organs organ NNS cord-306495-o0ah1gj9 36 22 from from IN cord-306495-o0ah1gj9 36 23 a a DT cord-306495-o0ah1gj9 36 24 donor donor NN cord-306495-o0ah1gj9 36 25 with with IN cord-306495-o0ah1gj9 36 26 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 36 27 can can MD cord-306495-o0ah1gj9 36 28 ever ever RB cord-306495-o0ah1gj9 36 29 be be VB cord-306495-o0ah1gj9 36 30 transplanted transplant VBN cord-306495-o0ah1gj9 36 31 warrants warrant NNS cord-306495-o0ah1gj9 36 32 careful careful JJ cord-306495-o0ah1gj9 36 33 evaluation evaluation NN cord-306495-o0ah1gj9 36 34 . . . cord-306495-o0ah1gj9 37 1 Issues issue NNS cord-306495-o0ah1gj9 37 2 to to TO cord-306495-o0ah1gj9 37 3 consider consider VB cord-306495-o0ah1gj9 37 4 include include VB cord-306495-o0ah1gj9 37 5 a a DT cord-306495-o0ah1gj9 37 6 ) ) -RRB- cord-306495-o0ah1gj9 37 7 the the DT cord-306495-o0ah1gj9 37 8 repercussions repercussion NNS cord-306495-o0ah1gj9 37 9 of of IN cord-306495-o0ah1gj9 37 10 SARS SARS NNP cord-306495-o0ah1gj9 37 11 - - HYPH cord-306495-o0ah1gj9 37 12 CoV-2 CoV-2 NNP cord-306495-o0ah1gj9 37 13 viremia viremia NN cord-306495-o0ah1gj9 37 14 ( ( -LRB- cord-306495-o0ah1gj9 37 15 which which WDT cord-306495-o0ah1gj9 37 16 is be VBZ cord-306495-o0ah1gj9 37 17 uncommon uncommon JJ cord-306495-o0ah1gj9 37 18 and and CC cord-306495-o0ah1gj9 37 19 of of IN cord-306495-o0ah1gj9 37 20 unclear unclear JJ cord-306495-o0ah1gj9 37 21 significance significance NN cord-306495-o0ah1gj9 37 22 ) ) -RRB- cord-306495-o0ah1gj9 37 23 [ [ -LRB- cord-306495-o0ah1gj9 37 24 2 2 CD cord-306495-o0ah1gj9 37 25 ] ] -RRB- cord-306495-o0ah1gj9 37 26 in in IN cord-306495-o0ah1gj9 37 27 the the DT cord-306495-o0ah1gj9 37 28 deceased deceased JJ cord-306495-o0ah1gj9 37 29 donor donor NN cord-306495-o0ah1gj9 37 30 and and CC cord-306495-o0ah1gj9 37 31 b b LS cord-306495-o0ah1gj9 37 32 ) ) -RRB- cord-306495-o0ah1gj9 37 33 whether whether IN cord-306495-o0ah1gj9 37 34 the the DT cord-306495-o0ah1gj9 37 35 use use NN cord-306495-o0ah1gj9 37 36 of of IN cord-306495-o0ah1gj9 37 37 any any DT cord-306495-o0ah1gj9 37 38 organ organ NN cord-306495-o0ah1gj9 37 39 is be VBZ cord-306495-o0ah1gj9 37 40 safe safe JJ cord-306495-o0ah1gj9 37 41 , , , cord-306495-o0ah1gj9 37 42 given give VBN cord-306495-o0ah1gj9 37 43 the the DT cord-306495-o0ah1gj9 37 44 dissemination dissemination NN cord-306495-o0ah1gj9 37 45 of of IN cord-306495-o0ah1gj9 37 46 SARS SARS NNP cord-306495-o0ah1gj9 37 47 - - HYPH cord-306495-o0ah1gj9 37 48 CoV-2 CoV-2 NNP cord-306495-o0ah1gj9 37 49 to to IN cord-306495-o0ah1gj9 37 50 kidneys kidney NNS cord-306495-o0ah1gj9 37 51 and and CC cord-306495-o0ah1gj9 37 52 other other JJ cord-306495-o0ah1gj9 37 53 organs organ NNS cord-306495-o0ah1gj9 37 54 in in IN cord-306495-o0ah1gj9 37 55 some some DT cord-306495-o0ah1gj9 37 56 patients patient NNS cord-306495-o0ah1gj9 37 57 [ [ -LRB- cord-306495-o0ah1gj9 37 58 10 10 CD cord-306495-o0ah1gj9 37 59 ] ] -RRB- cord-306495-o0ah1gj9 37 60 . . . cord-306495-o0ah1gj9 38 1 Current current JJ cord-306495-o0ah1gj9 38 2 guidelines guideline NNS cord-306495-o0ah1gj9 38 3 recommend recommend VBP cord-306495-o0ah1gj9 38 4 against against IN cord-306495-o0ah1gj9 38 5 the the DT cord-306495-o0ah1gj9 38 6 use use NN cord-306495-o0ah1gj9 38 7 of of IN cord-306495-o0ah1gj9 38 8 donors donor NNS cord-306495-o0ah1gj9 38 9 with with IN cord-306495-o0ah1gj9 38 10 a a DT cord-306495-o0ah1gj9 38 11 history history NN cord-306495-o0ah1gj9 38 12 of of IN cord-306495-o0ah1gj9 38 13 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 38 14 unless unless IN cord-306495-o0ah1gj9 38 15 a a DT cord-306495-o0ah1gj9 38 16 negative negative JJ cord-306495-o0ah1gj9 38 17 SARS SARS NNP cord-306495-o0ah1gj9 38 18 - - HYPH cord-306495-o0ah1gj9 38 19 CoV-2 CoV-2 NNP cord-306495-o0ah1gj9 38 20 PCR PCR NNP cord-306495-o0ah1gj9 38 21 result result NN cord-306495-o0ah1gj9 38 22 is be VBZ cord-306495-o0ah1gj9 38 23 documented[7 documented[7 NNP cord-306495-o0ah1gj9 38 24 ] ] -RRB- cord-306495-o0ah1gj9 38 25 . . . cord-306495-o0ah1gj9 39 1 Since since IN cord-306495-o0ah1gj9 39 2 chronic chronic JJ cord-306495-o0ah1gj9 39 3 nasopharyngeal nasopharyngeal JJ cord-306495-o0ah1gj9 39 4 shedding shedding NN cord-306495-o0ah1gj9 39 5 of of IN cord-306495-o0ah1gj9 39 6 ostensibly ostensibly RB cord-306495-o0ah1gj9 39 7 inert inert JJ cord-306495-o0ah1gj9 39 8 SARS SARS NNP cord-306495-o0ah1gj9 39 9 - - HYPH cord-306495-o0ah1gj9 39 10 CoV-2 CoV-2 NNP cord-306495-o0ah1gj9 39 11 appears appear VBZ cord-306495-o0ah1gj9 39 12 to to TO cord-306495-o0ah1gj9 39 13 be be VB cord-306495-o0ah1gj9 39 14 common common JJ cord-306495-o0ah1gj9 39 15 [ [ -LRB- cord-306495-o0ah1gj9 39 16 6 6 CD cord-306495-o0ah1gj9 39 17 ] ] -RRB- cord-306495-o0ah1gj9 39 18 , , , cord-306495-o0ah1gj9 39 19 these these DT cord-306495-o0ah1gj9 39 20 recommendations recommendation NNS cord-306495-o0ah1gj9 39 21 may may MD cord-306495-o0ah1gj9 39 22 be be VB cord-306495-o0ah1gj9 39 23 modified modify VBN cord-306495-o0ah1gj9 39 24 in in IN cord-306495-o0ah1gj9 39 25 the the DT cord-306495-o0ah1gj9 39 26 coming come VBG cord-306495-o0ah1gj9 39 27 years year NNS cord-306495-o0ah1gj9 39 28 . . . cord-306495-o0ah1gj9 40 1 Once once IN cord-306495-o0ah1gj9 40 2 an an DT cord-306495-o0ah1gj9 40 3 effective effective JJ cord-306495-o0ah1gj9 40 4 vaccine vaccine NN cord-306495-o0ah1gj9 40 5 is be VBZ cord-306495-o0ah1gj9 40 6 developed develop VBN cord-306495-o0ah1gj9 40 7 and and CC cord-306495-o0ah1gj9 40 8 mass mass NN cord-306495-o0ah1gj9 40 9 - - HYPH cord-306495-o0ah1gj9 40 10 administered administer VBN cord-306495-o0ah1gj9 40 11 , , , cord-306495-o0ah1gj9 40 12 these these DT cord-306495-o0ah1gj9 40 13 paradigms paradigm NNS cord-306495-o0ah1gj9 40 14 and and CC cord-306495-o0ah1gj9 40 15 many many JJ cord-306495-o0ah1gj9 40 16 others other NNS cord-306495-o0ah1gj9 40 17 will will MD cord-306495-o0ah1gj9 40 18 need need VB cord-306495-o0ah1gj9 40 19 to to TO cord-306495-o0ah1gj9 40 20 be be VB cord-306495-o0ah1gj9 40 21 revisited revisit VBN cord-306495-o0ah1gj9 40 22 . . . cord-306495-o0ah1gj9 41 1 In in IN cord-306495-o0ah1gj9 41 2 the the DT cord-306495-o0ah1gj9 41 3 past past JJ cord-306495-o0ah1gj9 41 4 decades decade NNS cord-306495-o0ah1gj9 41 5 , , , cord-306495-o0ah1gj9 41 6 the the DT cord-306495-o0ah1gj9 41 7 transplant transplant NN cord-306495-o0ah1gj9 41 8 community community NN cord-306495-o0ah1gj9 41 9 has have VBZ cord-306495-o0ah1gj9 41 10 had have VBN cord-306495-o0ah1gj9 41 11 to to TO cord-306495-o0ah1gj9 41 12 respond respond VB cord-306495-o0ah1gj9 41 13 to to IN cord-306495-o0ah1gj9 41 14 SARS SARS NNP cord-306495-o0ah1gj9 41 15 - - HYPH cord-306495-o0ah1gj9 41 16 CoV CoV NNP cord-306495-o0ah1gj9 41 17 , , , cord-306495-o0ah1gj9 41 18 pandemic pandemic JJ cord-306495-o0ah1gj9 41 19 H1N1 H1N1 NNP cord-306495-o0ah1gj9 41 20 , , , cord-306495-o0ah1gj9 41 21 MERS MERS NNP cord-306495-o0ah1gj9 41 22 - - HYPH cord-306495-o0ah1gj9 41 23 CoV CoV NNP cord-306495-o0ah1gj9 41 24 , , , cord-306495-o0ah1gj9 41 25 Ebolavirus Ebolavirus NNP cord-306495-o0ah1gj9 41 26 , , , cord-306495-o0ah1gj9 41 27 Zika Zika NNP cord-306495-o0ah1gj9 41 28 virus virus NN cord-306495-o0ah1gj9 41 29 , , , cord-306495-o0ah1gj9 41 30 and and CC cord-306495-o0ah1gj9 41 31 others other NNS cord-306495-o0ah1gj9 41 32 . . . cord-306495-o0ah1gj9 42 1 While while IN cord-306495-o0ah1gj9 42 2 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 42 3 is be VBZ cord-306495-o0ah1gj9 42 4 a a DT cord-306495-o0ah1gj9 42 5 pandemic pandemic NN cord-306495-o0ah1gj9 42 6 of of IN cord-306495-o0ah1gj9 42 7 unparalleled unparalleled JJ cord-306495-o0ah1gj9 42 8 proportions proportion NNS cord-306495-o0ah1gj9 42 9 , , , cord-306495-o0ah1gj9 42 10 transplant transplant NN cord-306495-o0ah1gj9 42 11 providers provider NNS cord-306495-o0ah1gj9 42 12 have have VBP cord-306495-o0ah1gj9 42 13 learned learn VBN cord-306495-o0ah1gj9 42 14 to to TO cord-306495-o0ah1gj9 42 15 adjust adjust VB cord-306495-o0ah1gj9 42 16 to to IN cord-306495-o0ah1gj9 42 17 a a DT cord-306495-o0ah1gj9 42 18 new new JJ cord-306495-o0ah1gj9 42 19 normal normal JJ cord-306495-o0ah1gj9 42 20 . . . cord-306495-o0ah1gj9 43 1 Looking look VBG cord-306495-o0ah1gj9 43 2 beyond beyond IN cord-306495-o0ah1gj9 43 3 the the DT cord-306495-o0ah1gj9 43 4 current current JJ cord-306495-o0ah1gj9 43 5 crisis crisis NN cord-306495-o0ah1gj9 43 6 , , , cord-306495-o0ah1gj9 43 7 transplant transplant NN cord-306495-o0ah1gj9 43 8 research research NN cord-306495-o0ah1gj9 43 9 efforts effort NNS cord-306495-o0ah1gj9 43 10 should should MD cord-306495-o0ah1gj9 43 11 focus focus VB cord-306495-o0ah1gj9 43 12 on on IN cord-306495-o0ah1gj9 43 13 pathogenesis pathogenesis NN cord-306495-o0ah1gj9 43 14 and and CC cord-306495-o0ah1gj9 43 15 virology virology NN cord-306495-o0ah1gj9 43 16 , , , cord-306495-o0ah1gj9 43 17 immunosuppression immunosuppression NN cord-306495-o0ah1gj9 43 18 strategies strategy NNS cord-306495-o0ah1gj9 43 19 , , , cord-306495-o0ah1gj9 43 20 donor donor NN cord-306495-o0ah1gj9 43 21 and and CC cord-306495-o0ah1gj9 43 22 recipient recipient NN cord-306495-o0ah1gj9 43 23 screening screening NN cord-306495-o0ah1gj9 43 24 issues issue NNS cord-306495-o0ah1gj9 43 25 , , , cord-306495-o0ah1gj9 43 26 and and CC cord-306495-o0ah1gj9 43 27 vaccine vaccine NN cord-306495-o0ah1gj9 43 28 and and CC cord-306495-o0ah1gj9 43 29 drug drug NN cord-306495-o0ah1gj9 43 30 trials trial NNS cord-306495-o0ah1gj9 43 31 in in IN cord-306495-o0ah1gj9 43 32 SOT SOT NNP cord-306495-o0ah1gj9 43 33 . . . cord-306495-o0ah1gj9 44 1 Finally finally RB cord-306495-o0ah1gj9 44 2 , , , cord-306495-o0ah1gj9 44 3 we -PRON- PRP cord-306495-o0ah1gj9 44 4 must must MD cord-306495-o0ah1gj9 44 5 prioritize prioritize VB cord-306495-o0ah1gj9 44 6 protecting protect VBG cord-306495-o0ah1gj9 44 7 SOT SOT NNP cord-306495-o0ah1gj9 44 8 A A NNP cord-306495-o0ah1gj9 44 9 c c NN cord-306495-o0ah1gj9 44 10 c c NN cord-306495-o0ah1gj9 44 11 e e NN cord-306495-o0ah1gj9 44 12 p p NN cord-306495-o0ah1gj9 44 13 t t NN cord-306495-o0ah1gj9 44 14 e e NN cord-306495-o0ah1gj9 44 15 d d NNP cord-306495-o0ah1gj9 44 16 M M NNP cord-306495-o0ah1gj9 44 17 a a NNP cord-306495-o0ah1gj9 44 18 n n NN cord-306495-o0ah1gj9 44 19 u u NNP cord-306495-o0ah1gj9 44 20 s s NNP cord-306495-o0ah1gj9 44 21 c c NN cord-306495-o0ah1gj9 44 22 r r NN cord-306495-o0ah1gj9 44 23 i i NN cord-306495-o0ah1gj9 44 24 p p NN cord-306495-o0ah1gj9 44 25 t t NN cord-306495-o0ah1gj9 44 26 5 5 CD cord-306495-o0ah1gj9 44 27 recipients recipient NNS cord-306495-o0ah1gj9 44 28 from from IN cord-306495-o0ah1gj9 44 29 SARS SARS NNP cord-306495-o0ah1gj9 44 30 - - HYPH cord-306495-o0ah1gj9 44 31 CoV-2 CoV-2 NNP cord-306495-o0ah1gj9 44 32 infection infection NN cord-306495-o0ah1gj9 44 33 by by IN cord-306495-o0ah1gj9 44 34 enforcing enforce VBG cord-306495-o0ah1gj9 44 35 social social JJ cord-306495-o0ah1gj9 44 36 distancing distancing NN cord-306495-o0ah1gj9 44 37 , , , cord-306495-o0ah1gj9 44 38 implementing implement VBG cord-306495-o0ah1gj9 44 39 universal universal JJ cord-306495-o0ah1gj9 44 40 masking masking NN cord-306495-o0ah1gj9 44 41 , , , cord-306495-o0ah1gj9 44 42 and and CC cord-306495-o0ah1gj9 44 43 utilizing utilize VBG cord-306495-o0ah1gj9 44 44 telemedicine telemedicine NN cord-306495-o0ah1gj9 44 45 services service NNS cord-306495-o0ah1gj9 44 46 to to TO cord-306495-o0ah1gj9 44 47 provide provide VB cord-306495-o0ah1gj9 44 48 care care NN cord-306495-o0ah1gj9 44 49 . . . cord-306495-o0ah1gj9 45 1 Funding funding NN cord-306495-o0ah1gj9 45 2 : : : cord-306495-o0ah1gj9 46 1 This this DT cord-306495-o0ah1gj9 46 2 work work NN cord-306495-o0ah1gj9 46 3 was be VBD cord-306495-o0ah1gj9 46 4 supported support VBN cord-306495-o0ah1gj9 46 5 by by IN cord-306495-o0ah1gj9 46 6 the the DT cord-306495-o0ah1gj9 46 7 National National NNP cord-306495-o0ah1gj9 46 8 Institutes Institutes NNPS cord-306495-o0ah1gj9 46 9 of of IN cord-306495-o0ah1gj9 46 10 Health Health NNP cord-306495-o0ah1gj9 46 11 through through IN cord-306495-o0ah1gj9 46 12 grant grant NN cord-306495-o0ah1gj9 46 13 number number NN cord-306495-o0ah1gj9 46 14 KL2TR001856 KL2TR001856 NNP cord-306495-o0ah1gj9 46 15 awarded award VBN cord-306495-o0ah1gj9 46 16 to to IN cord-306495-o0ah1gj9 46 17 G.H. G.H. NNP cord-306495-o0ah1gj9 46 18 Early early JJ cord-306495-o0ah1gj9 46 19 impact impact NN cord-306495-o0ah1gj9 46 20 of of IN cord-306495-o0ah1gj9 46 21 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 46 22 on on IN cord-306495-o0ah1gj9 46 23 transplant transplant NN cord-306495-o0ah1gj9 46 24 center center NN cord-306495-o0ah1gj9 46 25 practices practice NNS cord-306495-o0ah1gj9 46 26 and and CC cord-306495-o0ah1gj9 46 27 policies policy NNS cord-306495-o0ah1gj9 46 28 in in IN cord-306495-o0ah1gj9 46 29 the the DT cord-306495-o0ah1gj9 46 30 United United NNP cord-306495-o0ah1gj9 46 31 States States NNP cord-306495-o0ah1gj9 46 32 Clinical Clinical NNP cord-306495-o0ah1gj9 46 33 features feature NNS cord-306495-o0ah1gj9 46 34 of of IN cord-306495-o0ah1gj9 46 35 patients patient NNS cord-306495-o0ah1gj9 46 36 infected infect VBN cord-306495-o0ah1gj9 46 37 with with IN cord-306495-o0ah1gj9 46 38 2019 2019 CD cord-306495-o0ah1gj9 46 39 novel novel JJ cord-306495-o0ah1gj9 46 40 coronavirus coronavirus NN cord-306495-o0ah1gj9 46 41 in in IN cord-306495-o0ah1gj9 46 42 Wuhan Wuhan NNP cord-306495-o0ah1gj9 46 43 , , , cord-306495-o0ah1gj9 46 44 China China NNP cord-306495-o0ah1gj9 46 45 Inpatient Inpatient NNP cord-306495-o0ah1gj9 46 46 Mortality Mortality NNP cord-306495-o0ah1gj9 46 47 Among among IN cord-306495-o0ah1gj9 46 48 Solid Solid NNP cord-306495-o0ah1gj9 46 49 Organ Organ NNP cord-306495-o0ah1gj9 46 50 Transplant Transplant NNP cord-306495-o0ah1gj9 46 51 Recipients recipient NNS cord-306495-o0ah1gj9 46 52 Hospitalized hospitalize VBN cord-306495-o0ah1gj9 46 53 for for IN cord-306495-o0ah1gj9 46 54 Sepsis sepsis NN cord-306495-o0ah1gj9 46 55 and and CC cord-306495-o0ah1gj9 46 56 Severe severe JJ cord-306495-o0ah1gj9 46 57 Sepsis Sepsis NNP cord-306495-o0ah1gj9 46 58 Cryptococcus Cryptococcus NNP cord-306495-o0ah1gj9 46 59 neoformans neoforman VBZ cord-306495-o0ah1gj9 46 60 in in IN cord-306495-o0ah1gj9 46 61 organ organ NN cord-306495-o0ah1gj9 46 62 transplant transplant NN cord-306495-o0ah1gj9 46 63 recipients recipient NNS cord-306495-o0ah1gj9 46 64 : : : cord-306495-o0ah1gj9 46 65 impact impact NN cord-306495-o0ah1gj9 46 66 of of IN cord-306495-o0ah1gj9 46 67 calcineurin calcineurin NN cord-306495-o0ah1gj9 46 68 - - HYPH cord-306495-o0ah1gj9 46 69 inhibitor inhibitor NN cord-306495-o0ah1gj9 46 70 agents agent NNS cord-306495-o0ah1gj9 46 71 on on IN cord-306495-o0ah1gj9 46 72 mortality mortality NN cord-306495-o0ah1gj9 46 73 Characteristics characteristic NNS cord-306495-o0ah1gj9 46 74 of of IN cord-306495-o0ah1gj9 46 75 and and CC cord-306495-o0ah1gj9 46 76 Important important JJ cord-306495-o0ah1gj9 46 77 Lessons lesson NNS cord-306495-o0ah1gj9 46 78 From from IN cord-306495-o0ah1gj9 46 79 the the DT cord-306495-o0ah1gj9 46 80 Coronavirus Coronavirus NNP cord-306495-o0ah1gj9 46 81 Disease Disease NNP cord-306495-o0ah1gj9 46 82 2019 2019 CD cord-306495-o0ah1gj9 47 1 ( ( -LRB- cord-306495-o0ah1gj9 47 2 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 47 3 ) ) -RRB- cord-306495-o0ah1gj9 47 4 Outbreak outbreak NN cord-306495-o0ah1gj9 47 5 in in IN cord-306495-o0ah1gj9 47 6 China China NNP cord-306495-o0ah1gj9 47 7 : : : cord-306495-o0ah1gj9 48 1 Summary summary NN cord-306495-o0ah1gj9 48 2 of of IN cord-306495-o0ah1gj9 48 3 a a DT cord-306495-o0ah1gj9 48 4 Report Report NNP cord-306495-o0ah1gj9 48 5 of of IN cord-306495-o0ah1gj9 48 6 72314 72314 CD cord-306495-o0ah1gj9 48 7 Cases case NNS cord-306495-o0ah1gj9 48 8 From from IN cord-306495-o0ah1gj9 48 9 the the DT cord-306495-o0ah1gj9 48 10 Chinese Chinese NNP cord-306495-o0ah1gj9 48 11 Center Center NNP cord-306495-o0ah1gj9 48 12 for for IN cord-306495-o0ah1gj9 48 13 Disease Disease NNP cord-306495-o0ah1gj9 48 14 Control Control NNP cord-306495-o0ah1gj9 48 15 and and CC cord-306495-o0ah1gj9 49 1 Prevention prevention NN cord-306495-o0ah1gj9 49 2 Virological virological JJ cord-306495-o0ah1gj9 49 3 assessment assessment NN cord-306495-o0ah1gj9 49 4 of of IN cord-306495-o0ah1gj9 49 5 hospitalized hospitalize VBN cord-306495-o0ah1gj9 49 6 patients patient NNS cord-306495-o0ah1gj9 49 7 with with IN cord-306495-o0ah1gj9 49 8 COVID-2019 COVID-2019 NNP cord-306495-o0ah1gj9 49 9 Deep Deep NNP cord-306495-o0ah1gj9 49 10 immune immune JJ cord-306495-o0ah1gj9 49 11 profiling profiling NN cord-306495-o0ah1gj9 49 12 of of IN cord-306495-o0ah1gj9 49 13 COVID-19 covid-19 JJ cord-306495-o0ah1gj9 49 14 patients patient NNS cord-306495-o0ah1gj9 49 15 reveals reveal VBZ cord-306495-o0ah1gj9 49 16 distinct distinct JJ cord-306495-o0ah1gj9 49 17 immunotypes immunotype NNS cord-306495-o0ah1gj9 49 18 with with IN cord-306495-o0ah1gj9 49 19 therapeutic therapeutic JJ cord-306495-o0ah1gj9 49 20 implications implication NNS cord-306495-o0ah1gj9 50 1 Dexamethasone dexamethasone NN cord-306495-o0ah1gj9 50 2 in in IN cord-306495-o0ah1gj9 50 3 Hospitalized Hospitalized NNP cord-306495-o0ah1gj9 50 4 Patients Patients NNP cord-306495-o0ah1gj9 50 5 with with IN cord-306495-o0ah1gj9 50 6 Covid-19 Covid-19 NNP cord-306495-o0ah1gj9 50 7 -Preliminary -Preliminary NNP cord-306495-o0ah1gj9 50 8 Report Report NNP cord-306495-o0ah1gj9 50 9 Renal Renal NNP cord-306495-o0ah1gj9 50 10 histopathological histopathological JJ cord-306495-o0ah1gj9 50 11 analysis analysis NN cord-306495-o0ah1gj9 50 12 of of IN cord-306495-o0ah1gj9 50 13 26 26 CD cord-306495-o0ah1gj9 50 14 postmortem postmortem JJ cord-306495-o0ah1gj9 50 15 findings finding NNS cord-306495-o0ah1gj9 50 16 of of IN cord-306495-o0ah1gj9 50 17 patients patient NNS cord-306495-o0ah1gj9 50 18 with with IN cord-306495-o0ah1gj9 50 19 COVID-19 COVID-19 NNP cord-306495-o0ah1gj9 50 20 in in IN cord-306495-o0ah1gj9 50 21 China China NNP