id sid tid token lemma pos cord-300848-0igfcixy 1 1 key key NN cord-300848-0igfcixy 1 2 : : : cord-300848-0igfcixy 2 1 cord-300848 cord-300848 NNP cord-300848-0igfcixy 2 2 - - HYPH cord-300848-0igfcixy 2 3 0igfcixy 0igfcixy CD cord-300848-0igfcixy 2 4 authors author NNS cord-300848-0igfcixy 2 5 : : : cord-300848-0igfcixy 2 6 Meijers Meijers NNP cord-300848-0igfcixy 2 7 , , , cord-300848-0igfcixy 2 8 Björn Björn NNP cord-300848-0igfcixy 2 9 ; ; : cord-300848-0igfcixy 2 10 Hilbrands Hilbrands NNP cord-300848-0igfcixy 2 11 , , , cord-300848-0igfcixy 2 12 Luuk Luuk NNP cord-300848-0igfcixy 2 13 B B NNP cord-300848-0igfcixy 2 14 title title NN cord-300848-0igfcixy 2 15 : : : cord-300848-0igfcixy 2 16 The the DT cord-300848-0igfcixy 2 17 clinical clinical JJ cord-300848-0igfcixy 2 18 characteristics characteristic NNS cord-300848-0igfcixy 2 19 of of IN cord-300848-0igfcixy 2 20 coronavirus coronavirus NN cord-300848-0igfcixy 2 21 - - HYPH cord-300848-0igfcixy 2 22 associated associate VBN cord-300848-0igfcixy 2 23 nephropathy nephropathy NN cord-300848-0igfcixy 2 24 date date NN cord-300848-0igfcixy 2 25 : : : cord-300848-0igfcixy 2 26 2020 2020 CD cord-300848-0igfcixy 2 27 - - HYPH cord-300848-0igfcixy 2 28 09 09 CD cord-300848-0igfcixy 2 29 - - HYPH cord-300848-0igfcixy 2 30 02 02 CD cord-300848-0igfcixy 2 31 journal journal NN cord-300848-0igfcixy 2 32 : : : cord-300848-0igfcixy 3 1 Nephrol Nephrol NNP cord-300848-0igfcixy 3 2 Dial Dial NNP cord-300848-0igfcixy 3 3 Transplant Transplant NNP cord-300848-0igfcixy 3 4 DOI doi NN cord-300848-0igfcixy 3 5 : : : cord-300848-0igfcixy 3 6 10.1093 10.1093 CD cord-300848-0igfcixy 3 7 / / SYM cord-300848-0igfcixy 3 8 ndt ndt NNP cord-300848-0igfcixy 3 9 / / SYM cord-300848-0igfcixy 3 10 gfaa197 gfaa197 NNP cord-300848-0igfcixy 3 11 sha sha NNP cord-300848-0igfcixy 3 12 : : : cord-300848-0igfcixy 4 1 968eefafdffe878dc2e65a7cf46d9dab0255b688 968eefafdffe878dc2e65a7cf46d9dab0255b688 NNP cord-300848-0igfcixy 4 2 doc_id doc_id CD cord-300848-0igfcixy 4 3 : : : cord-300848-0igfcixy 5 1 300848 300848 CD cord-300848-0igfcixy 5 2 cord_uid cord_uid NN cord-300848-0igfcixy 5 3 : : : cord-300848-0igfcixy 6 1 0igfcixy 0igfcixy . cord-300848-0igfcixy 7 1 nan nan NNP cord-300848-0igfcixy 8 1 We -PRON- PRP cord-300848-0igfcixy 8 2 are be VBP cord-300848-0igfcixy 8 3 facing face VBG cord-300848-0igfcixy 8 4 a a DT cord-300848-0igfcixy 8 5 full full RB cord-300848-0igfcixy 8 6 - - HYPH cord-300848-0igfcixy 8 7 blown blow VBN cord-300848-0igfcixy 8 8 pandemic pandemic NN cord-300848-0igfcixy 8 9 , , , cord-300848-0igfcixy 8 10 caused cause VBN cord-300848-0igfcixy 8 11 by by IN cord-300848-0igfcixy 8 12 a a DT cord-300848-0igfcixy 8 13 recently recently RB cord-300848-0igfcixy 8 14 identified identify VBN cord-300848-0igfcixy 8 15 beta beta NN cord-300848-0igfcixy 8 16 - - HYPH cord-300848-0igfcixy 8 17 coronavirus coronavirus NN cord-300848-0igfcixy 8 18 [ [ -LRB- cord-300848-0igfcixy 8 19 1 1 CD cord-300848-0igfcixy 8 20 ] ] -RRB- cord-300848-0igfcixy 8 21 now now RB cord-300848-0igfcixy 8 22 known know VBN cord-300848-0igfcixy 8 23 as as IN cord-300848-0igfcixy 8 24 the the DT cord-300848-0igfcixy 8 25 severe severe JJ cord-300848-0igfcixy 8 26 acute acute JJ cord-300848-0igfcixy 8 27 respiratory respiratory JJ cord-300848-0igfcixy 8 28 syndrome syndrome NN cord-300848-0igfcixy 8 29 coronavirus coronavirus NN cord-300848-0igfcixy 8 30 2 2 CD cord-300848-0igfcixy 9 1 ( ( -LRB- cord-300848-0igfcixy 9 2 SARS SARS NNP cord-300848-0igfcixy 9 3 - - HYPH cord-300848-0igfcixy 9 4 CoV-2 CoV-2 NNP cord-300848-0igfcixy 9 5 ) ) -RRB- cord-300848-0igfcixy 9 6 . . . cord-300848-0igfcixy 10 1 The the DT cord-300848-0igfcixy 10 2 clinical clinical JJ cord-300848-0igfcixy 10 3 disease disease NN cord-300848-0igfcixy 10 4 , , , cord-300848-0igfcixy 10 5 coined coin VBN cord-300848-0igfcixy 10 6 coronavirus coronavirus NN cord-300848-0igfcixy 10 7 disease disease NN cord-300848-0igfcixy 10 8 2019 2019 CD cord-300848-0igfcixy 10 9 ( ( -LRB- cord-300848-0igfcixy 10 10 COVID- COVID- NNP cord-300848-0igfcixy 10 11 19 19 CD cord-300848-0igfcixy 10 12 ) ) -RRB- cord-300848-0igfcixy 10 13 , , , cord-300848-0igfcixy 10 14 is be VBZ cord-300848-0igfcixy 10 15 quite quite RB cord-300848-0igfcixy 10 16 heterogeneous heterogeneous JJ cord-300848-0igfcixy 10 17 . . . cord-300848-0igfcixy 11 1 While while IN cord-300848-0igfcixy 11 2 most most JJS cord-300848-0igfcixy 11 3 patients patient NNS cord-300848-0igfcixy 11 4 are be VBP cord-300848-0igfcixy 11 5 asymptomatic asymptomatic JJ cord-300848-0igfcixy 11 6 or or CC cord-300848-0igfcixy 11 7 have have VBP cord-300848-0igfcixy 11 8 minor minor JJ cord-300848-0igfcixy 11 9 symptoms symptom NNS cord-300848-0igfcixy 11 10 , , , cord-300848-0igfcixy 11 11 a a DT cord-300848-0igfcixy 11 12 minority minority NN cord-300848-0igfcixy 11 13 of of IN cord-300848-0igfcixy 11 14 patients patient NNS cord-300848-0igfcixy 11 15 develop develop VBP cord-300848-0igfcixy 11 16 more more RBR cord-300848-0igfcixy 11 17 serious serious JJ cord-300848-0igfcixy 11 18 and and CC cord-300848-0igfcixy 11 19 potentially potentially RB cord-300848-0igfcixy 11 20 life life NN cord-300848-0igfcixy 11 21 - - HYPH cord-300848-0igfcixy 11 22 threatening threaten VBG cord-300848-0igfcixy 11 23 respiratory respiratory JJ cord-300848-0igfcixy 11 24 disease disease NN cord-300848-0igfcixy 11 25 [ [ -LRB- cord-300848-0igfcixy 11 26 2 2 CD cord-300848-0igfcixy 11 27 ] ] -RRB- cord-300848-0igfcixy 11 28 . . . cord-300848-0igfcixy 12 1 In in IN cord-300848-0igfcixy 12 2 this this DT cord-300848-0igfcixy 12 3 issue issue NN cord-300848-0igfcixy 12 4 of of IN cord-300848-0igfcixy 12 5 Nephrology Nephrology NNP cord-300848-0igfcixy 12 6 Dialysis Dialysis NNP cord-300848-0igfcixy 12 7 Transplantation Transplantation NNP cord-300848-0igfcixy 12 8 , , , cord-300848-0igfcixy 12 9 Portolés Portolés NNP cord-300848-0igfcixy 12 10 and and CC cord-300848-0igfcixy 12 11 coworkers coworker NNS cord-300848-0igfcixy 12 12 report report VBP cord-300848-0igfcixy 12 13 on on IN cord-300848-0igfcixy 12 14 a a DT cord-300848-0igfcixy 12 15 large large JJ cord-300848-0igfcixy 12 16 European european JJ cord-300848-0igfcixy 12 17 cohort cohort NN cord-300848-0igfcixy 12 18 of of IN cord-300848-0igfcixy 12 19 patients patient NNS cord-300848-0igfcixy 12 20 with with IN cord-300848-0igfcixy 12 21 COVID-19 COVID-19 NNP cord-300848-0igfcixy 12 22 . . . cord-300848-0igfcixy 13 1 They -PRON- PRP cord-300848-0igfcixy 13 2 explore explore VBP cord-300848-0igfcixy 13 3 kidney kidney NN cord-300848-0igfcixy 13 4 involvement involvement NN cord-300848-0igfcixy 13 5 as as IN cord-300848-0igfcixy 13 6 part part NN cord-300848-0igfcixy 13 7 of of IN cord-300848-0igfcixy 13 8 the the DT cord-300848-0igfcixy 13 9 clinical clinical JJ cord-300848-0igfcixy 13 10 spectrum spectrum NN cord-300848-0igfcixy 13 11 of of IN cord-300848-0igfcixy 13 12 SARS SARS NNP cord-300848-0igfcixy 13 13 - - HYPH cord-300848-0igfcixy 13 14 CoV-2 CoV-2 NNP cord-300848-0igfcixy 13 15 infection infection NN cord-300848-0igfcixy 13 16 [ [ -LRB- cord-300848-0igfcixy 13 17 3 3 CD cord-300848-0igfcixy 13 18 ] ] -RRB- cord-300848-0igfcixy 13 19 . . . cord-300848-0igfcixy 14 1 For for IN cord-300848-0igfcixy 14 2 cell cell NN cord-300848-0igfcixy 14 3 entry entry NN cord-300848-0igfcixy 14 4 , , , cord-300848-0igfcixy 14 5 the the DT cord-300848-0igfcixy 14 6 virus virus NN cord-300848-0igfcixy 14 7 uses use VBZ cord-300848-0igfcixy 14 8 a a DT cord-300848-0igfcixy 14 9 spike spike NN cord-300848-0igfcixy 14 10 protein protein NN cord-300848-0igfcixy 14 11 to to TO cord-300848-0igfcixy 14 12 bind bind VB cord-300848-0igfcixy 14 13 to to IN cord-300848-0igfcixy 14 14 an an DT cord-300848-0igfcixy 14 15 extracellular extracellular JJ cord-300848-0igfcixy 14 16 domain domain NN cord-300848-0igfcixy 14 17 of of IN cord-300848-0igfcixy 14 18 the the DT cord-300848-0igfcixy 14 19 human human JJ cord-300848-0igfcixy 14 20 angiotensin angiotensin NN cord-300848-0igfcixy 14 21 - - HYPH cord-300848-0igfcixy 14 22 converting convert VBG cord-300848-0igfcixy 14 23 enzyme enzyme NN cord-300848-0igfcixy 14 24 2 2 CD cord-300848-0igfcixy 14 25 ( ( -LRB- cord-300848-0igfcixy 14 26 ACE2 ACE2 NNP cord-300848-0igfcixy 14 27 ) ) -RRB- cord-300848-0igfcixy 14 28 [ [ -LRB- cord-300848-0igfcixy 14 29 4 4 CD cord-300848-0igfcixy 14 30 , , , cord-300848-0igfcixy 14 31 5 5 CD cord-300848-0igfcixy 14 32 ] ] -RRB- cord-300848-0igfcixy 14 33 . . . cord-300848-0igfcixy 15 1 ACE2 ACE2 NNP cord-300848-0igfcixy 15 2 is be VBZ cord-300848-0igfcixy 15 3 a a DT cord-300848-0igfcixy 15 4 carboxypeptidase carboxypeptidase NN cord-300848-0igfcixy 15 5 , , , cord-300848-0igfcixy 15 6 hydrolysing hydrolyse VBG cord-300848-0igfcixy 15 7 single single JJ cord-300848-0igfcixy 15 8 C c NN cord-300848-0igfcixy 15 9 - - HYPH cord-300848-0igfcixy 15 10 terminal terminal NN cord-300848-0igfcixy 15 11 amino amino NN cord-300848-0igfcixy 15 12 acids acid NNS cord-300848-0igfcixy 15 13 from from IN cord-300848-0igfcixy 15 14 peptides peptide NNS cord-300848-0igfcixy 15 15 , , , cord-300848-0igfcixy 15 16 e.g. e.g. RB cord-300848-0igfcixy 15 17 angiotensin angiotensin NN cord-300848-0igfcixy 15 18 I I NNP cord-300848-0igfcixy 15 19 and and CC cord-300848-0igfcixy 15 20 angiotensin angiotensin NN cord-300848-0igfcixy 15 21 II II NNP cord-300848-0igfcixy 15 22 [ [ -LRB- cord-300848-0igfcixy 15 23 6 6 CD cord-300848-0igfcixy 15 24 ] ] -RRB- cord-300848-0igfcixy 15 25 . . . cord-300848-0igfcixy 16 1 High high JJ cord-300848-0igfcixy 16 2 expression expression NN cord-300848-0igfcixy 16 3 levels level NNS cord-300848-0igfcixy 16 4 of of IN cord-300848-0igfcixy 16 5 ACE2 ACE2 NNP cord-300848-0igfcixy 16 6 in in IN cord-300848-0igfcixy 16 7 the the DT cord-300848-0igfcixy 16 8 upper upper JJ cord-300848-0igfcixy 16 9 and and CC cord-300848-0igfcixy 16 10 lower low JJR cord-300848-0igfcixy 16 11 airways airway NNS cord-300848-0igfcixy 16 12 explain explain VBP cord-300848-0igfcixy 16 13 the the DT cord-300848-0igfcixy 16 14 respiratory respiratory JJ cord-300848-0igfcixy 16 15 tropism tropism NN cord-300848-0igfcixy 16 16 of of IN cord-300848-0igfcixy 16 17 SARS SARS NNP cord-300848-0igfcixy 16 18 - - HYPH cord-300848-0igfcixy 16 19 CoV-2 CoV-2 NNP cord-300848-0igfcixy 16 20 . . . cord-300848-0igfcixy 17 1 The the DT cord-300848-0igfcixy 17 2 kidney kidney NN cord-300848-0igfcixy 17 3 is be VBZ cord-300848-0igfcixy 17 4 another another DT cord-300848-0igfcixy 17 5 organ organ NN cord-300848-0igfcixy 17 6 with with IN cord-300848-0igfcixy 17 7 ACE2 ACE2 NNP cord-300848-0igfcixy 17 8 expression expression NN cord-300848-0igfcixy 17 9 , , , cord-300848-0igfcixy 17 10 predominantly predominantly RB cord-300848-0igfcixy 17 11 by by IN cord-300848-0igfcixy 17 12 proximal proximal JJ cord-300848-0igfcixy 17 13 tubular tubular JJ cord-300848-0igfcixy 17 14 cells cell NNS cord-300848-0igfcixy 17 15 and and CC cord-300848-0igfcixy 17 16 podocytes podocytes NNP cord-300848-0igfcixy 17 17 [ [ -LRB- cord-300848-0igfcixy 17 18 7 7 CD cord-300848-0igfcixy 17 19 ] ] -RRB- cord-300848-0igfcixy 17 20 . . . cord-300848-0igfcixy 18 1 Until until IN cord-300848-0igfcixy 18 2 very very RB cord-300848-0igfcixy 18 3 recently recently RB cord-300848-0igfcixy 18 4 , , , cord-300848-0igfcixy 18 5 it -PRON- PRP cord-300848-0igfcixy 18 6 was be VBD cord-300848-0igfcixy 18 7 not not RB cord-300848-0igfcixy 18 8 known know VBN cord-300848-0igfcixy 18 9 whether whether IN cord-300848-0igfcixy 18 10 this this DT cord-300848-0igfcixy 18 11 would would MD cord-300848-0igfcixy 18 12 promote promote VB cord-300848-0igfcixy 18 13 kidney kidney NN cord-300848-0igfcixy 18 14 tropism tropism NN cord-300848-0igfcixy 18 15 . . . cord-300848-0igfcixy 19 1 The the DT cord-300848-0igfcixy 19 2 virus virus NN cord-300848-0igfcixy 19 3 that that WDT cord-300848-0igfcixy 19 4 caused cause VBD cord-300848-0igfcixy 19 5 the the DT cord-300848-0igfcixy 19 6 SARS SARS NNP cord-300848-0igfcixy 19 7 epidemic epidemic NN cord-300848-0igfcixy 19 8 in in IN cord-300848-0igfcixy 19 9 2003 2003 CD cord-300848-0igfcixy 19 10 ( ( -LRB- cord-300848-0igfcixy 19 11 SARS SARS NNP cord-300848-0igfcixy 19 12 - - HYPH cord-300848-0igfcixy 19 13 CoV CoV NNP cord-300848-0igfcixy 19 14 ) ) -RRB- cord-300848-0igfcixy 19 15 equally equally RB cord-300848-0igfcixy 19 16 uses use VBZ cord-300848-0igfcixy 19 17 ACE2 ACE2 NNP cord-300848-0igfcixy 19 18 as as IN cord-300848-0igfcixy 19 19 a a DT cord-300848-0igfcixy 19 20 cellular cellular JJ cord-300848-0igfcixy 19 21 receptor receptor NN cord-300848-0igfcixy 19 22 for for IN cord-300848-0igfcixy 19 23 cell cell NN cord-300848-0igfcixy 19 24 entry entry NN cord-300848-0igfcixy 19 25 . . . cord-300848-0igfcixy 20 1 While while IN cord-300848-0igfcixy 20 2 a a DT cord-300848-0igfcixy 20 3 minority minority NN cord-300848-0igfcixy 20 4 of of IN cord-300848-0igfcixy 20 5 SARS SARS NNP cord-300848-0igfcixy 20 6 - - HYPH cord-300848-0igfcixy 20 7 CoV CoV NNP cord-300848-0igfcixy 20 8 patients patient NNS cord-300848-0igfcixy 20 9 did do VBD cord-300848-0igfcixy 20 10 develop develop VB cord-300848-0igfcixy 20 11 acute acute JJ cord-300848-0igfcixy 20 12 kidney kidney NN cord-300848-0igfcixy 20 13 injury injury NN cord-300848-0igfcixy 20 14 ( ( -LRB- cord-300848-0igfcixy 20 15 AKI AKI NNP cord-300848-0igfcixy 20 16 ) ) -RRB- cord-300848-0igfcixy 20 17 , , , cord-300848-0igfcixy 20 18 this this DT cord-300848-0igfcixy 20 19 was be VBD cord-300848-0igfcixy 20 20 attributed attribute VBN cord-300848-0igfcixy 20 21 to to IN cord-300848-0igfcixy 20 22 critical critical JJ cord-300848-0igfcixy 20 23 illness illness NN cord-300848-0igfcixy 20 24 with with IN cord-300848-0igfcixy 20 25 acute acute JJ cord-300848-0igfcixy 20 26 tubular tubular JJ cord-300848-0igfcixy 20 27 necrosis necrosis NN cord-300848-0igfcixy 20 28 in in IN cord-300848-0igfcixy 20 29 post post JJ cord-300848-0igfcixy 20 30 - - JJ cord-300848-0igfcixy 20 31 mortem mortem JJ cord-300848-0igfcixy 20 32 kidney kidney NN cord-300848-0igfcixy 20 33 tissue tissue NN cord-300848-0igfcixy 20 34 . . . cord-300848-0igfcixy 21 1 With with IN cord-300848-0igfcixy 21 2 electron electron NN cord-300848-0igfcixy 21 3 microscopy microscopy NNS cord-300848-0igfcixy 21 4 , , , cord-300848-0igfcixy 21 5 no no DT cord-300848-0igfcixy 21 6 viral viral JJ cord-300848-0igfcixy 21 7 particles particle NNS cord-300848-0igfcixy 21 8 could could MD cord-300848-0igfcixy 21 9 be be VB cord-300848-0igfcixy 21 10 detected detect VBN cord-300848-0igfcixy 21 11 in in IN cord-300848-0igfcixy 21 12 these these DT cord-300848-0igfcixy 21 13 specimens specimen NNS cord-300848-0igfcixy 21 14 [ [ -LRB- cord-300848-0igfcixy 21 15 8 8 CD cord-300848-0igfcixy 21 16 ] ] -RRB- cord-300848-0igfcixy 21 17 . . . cord-300848-0igfcixy 22 1 In in IN cord-300848-0igfcixy 22 2 kidney kidney NN cord-300848-0igfcixy 22 3 tissue tissue NN cord-300848-0igfcixy 22 4 obtained obtain VBN cord-300848-0igfcixy 22 5 at at IN cord-300848-0igfcixy 22 6 autopsy autopsy NN cord-300848-0igfcixy 22 7 of of IN cord-300848-0igfcixy 22 8 26 26 CD cord-300848-0igfcixy 22 9 critically critically RB cord-300848-0igfcixy 22 10 ill ill JJ cord-300848-0igfcixy 22 11 patients patient NNS cord-300848-0igfcixy 22 12 with with IN cord-300848-0igfcixy 22 13 COVID-19 COVID-19 NNP cord-300848-0igfcixy 22 14 , , , cord-300848-0igfcixy 22 15 diffuse diffuse VB cord-300848-0igfcixy 22 16 proximal proximal JJ cord-300848-0igfcixy 22 17 tubule tubule NN cord-300848-0igfcixy 22 18 injury injury NN cord-300848-0igfcixy 22 19 also also RB cord-300848-0igfcixy 22 20 was be VBD cord-300848-0igfcixy 22 21 the the DT cord-300848-0igfcixy 22 22 main main JJ cord-300848-0igfcixy 22 23 finding finding NN cord-300848-0igfcixy 22 24 on on IN cord-300848-0igfcixy 22 25 light light JJ cord-300848-0igfcixy 22 26 microscopy microscopy NNS cord-300848-0igfcixy 22 27 [ [ -LRB- cord-300848-0igfcixy 22 28 9 9 CD cord-300848-0igfcixy 22 29 ] ] -RRB- cord-300848-0igfcixy 22 30 . . . cord-300848-0igfcixy 23 1 In in IN cord-300848-0igfcixy 23 2 a a DT cord-300848-0igfcixy 23 3 second second JJ cord-300848-0igfcixy 23 4 series series NN cord-300848-0igfcixy 23 5 of of IN cord-300848-0igfcixy 23 6 three three CD cord-300848-0igfcixy 23 7 patients patient NNS cord-300848-0igfcixy 23 8 , , , cord-300848-0igfcixy 23 9 of of IN cord-300848-0igfcixy 23 10 which which WDT cord-300848-0igfcixy 23 11 kidney kidney NN cord-300848-0igfcixy 23 12 tissue tissue NN cord-300848-0igfcixy 23 13 was be VBD cord-300848-0igfcixy 23 14 available available JJ cord-300848-0igfcixy 23 15 in in IN cord-300848-0igfcixy 23 16 two two CD cord-300848-0igfcixy 23 17 ( ( -LRB- cord-300848-0igfcixy 23 18 one one CD cord-300848-0igfcixy 23 19 native native JJ cord-300848-0igfcixy 23 20 kidney kidney NN cord-300848-0igfcixy 23 21 and and CC cord-300848-0igfcixy 23 22 one one CD cord-300848-0igfcixy 23 23 transplanted transplant VBN cord-300848-0igfcixy 23 24 kidney kidney NN cord-300848-0igfcixy 23 25 ) ) -RRB- cord-300848-0igfcixy 23 26 , , , cord-300848-0igfcixy 23 27 clear clear JJ cord-300848-0igfcixy 23 28 endotheliitis endotheliitis NNP cord-300848-0igfcixy 23 29 was be VBD cord-300848-0igfcixy 23 30 noted note VBN cord-300848-0igfcixy 23 31 [ [ -LRB- cord-300848-0igfcixy 23 32 10 10 CD cord-300848-0igfcixy 23 33 ] ] -RRB- cord-300848-0igfcixy 23 34 . . . cord-300848-0igfcixy 24 1 In in IN cord-300848-0igfcixy 24 2 these these DT cord-300848-0igfcixy 24 3 studies study NNS cord-300848-0igfcixy 24 4 , , , cord-300848-0igfcixy 24 5 viruslike viruslike JJ cord-300848-0igfcixy 24 6 particles particle NNS cord-300848-0igfcixy 24 7 were be VBD cord-300848-0igfcixy 24 8 observed observe VBN cord-300848-0igfcixy 24 9 on on IN cord-300848-0igfcixy 24 10 electron electron NN cord-300848-0igfcixy 24 11 microscopy microscopy NN cord-300848-0igfcixy 24 12 in in IN cord-300848-0igfcixy 24 13 tubular tubular JJ cord-300848-0igfcixy 24 14 epithelial epithelial JJ cord-300848-0igfcixy 24 15 cells cell NNS cord-300848-0igfcixy 24 16 , , , cord-300848-0igfcixy 24 17 podocytes podocyte NNS cord-300848-0igfcixy 24 18 and and CC cord-300848-0igfcixy 24 19 endothelium endothelium NN cord-300848-0igfcixy 24 20 . . . cord-300848-0igfcixy 25 1 However however RB cord-300848-0igfcixy 25 2 , , , cord-300848-0igfcixy 25 3 whether whether IN cord-300848-0igfcixy 25 4 these these DT cord-300848-0igfcixy 25 5 structures structure NNS cord-300848-0igfcixy 25 6 actually actually RB cord-300848-0igfcixy 25 7 are be VBP cord-300848-0igfcixy 25 8 virions virion NNS cord-300848-0igfcixy 25 9 is be VBZ cord-300848-0igfcixy 25 10 disputed dispute VBN cord-300848-0igfcixy 25 11 by by IN cord-300848-0igfcixy 25 12 others other NNS cord-300848-0igfcixy 25 13 [ [ -LRB- cord-300848-0igfcixy 25 14 11 11 CD cord-300848-0igfcixy 25 15 , , , cord-300848-0igfcixy 25 16 12 12 CD cord-300848-0igfcixy 25 17 ] ] -RRB- cord-300848-0igfcixy 25 18 . . . cord-300848-0igfcixy 26 1 Nevertheless nevertheless RB cord-300848-0igfcixy 26 2 , , , cord-300848-0igfcixy 26 3 the the DT cord-300848-0igfcixy 26 4 presence presence NN cord-300848-0igfcixy 26 5 of of IN cord-300848-0igfcixy 26 6 SARS SARS NNP cord-300848-0igfcixy 26 7 - - HYPH cord-300848-0igfcixy 26 8 CoV-2 CoV-2 NNP cord-300848-0igfcixy 26 9 RNA RNA NNP cord-300848-0igfcixy 26 10 and and CC cord-300848-0igfcixy 26 11 proteins protein NNS cord-300848-0igfcixy 26 12 has have VBZ cord-300848-0igfcixy 26 13 convincingly convincingly RB cord-300848-0igfcixy 26 14 been be VBN cord-300848-0igfcixy 26 15 demonstrated demonstrate VBN cord-300848-0igfcixy 26 16 in in IN cord-300848-0igfcixy 26 17 glomerular glomerular JJ cord-300848-0igfcixy 26 18 epithelial epithelial NN cord-300848-0igfcixy 26 19 , , , cord-300848-0igfcixy 26 20 endothelial endothelial JJ cord-300848-0igfcixy 26 21 and and CC cord-300848-0igfcixy 26 22 tubular tubular JJ cord-300848-0igfcixy 26 23 cells cell NNS cord-300848-0igfcixy 26 24 of of IN cord-300848-0igfcixy 26 25 patients patient NNS cord-300848-0igfcixy 26 26 who who WP cord-300848-0igfcixy 26 27 had have VBD cord-300848-0igfcixy 26 28 died die VBN cord-300848-0igfcixy 26 29 from from IN cord-300848-0igfcixy 26 30 COVID-19 COVID-19 NNP cord-300848-0igfcixy 26 31 [ [ -LRB- cord-300848-0igfcixy 26 32 9 9 CD cord-300848-0igfcixy 26 33 , , , cord-300848-0igfcixy 26 34 13 13 CD cord-300848-0igfcixy 26 35 ] ] -RRB- cord-300848-0igfcixy 26 36 . . . cord-300848-0igfcixy 27 1 These these DT cord-300848-0igfcixy 27 2 findings finding NNS cord-300848-0igfcixy 27 3 indicate indicate VBP cord-300848-0igfcixy 27 4 kidney kidney NN cord-300848-0igfcixy 27 5 tropism tropism NN cord-300848-0igfcixy 27 6 of of IN cord-300848-0igfcixy 27 7 SARS SARS NNP cord-300848-0igfcixy 27 8 - - HYPH cord-300848-0igfcixy 27 9 CoV-2 CoV-2 NNP cord-300848-0igfcixy 27 10 and and CC cord-300848-0igfcixy 27 11 may may MD cord-300848-0igfcixy 27 12 promote promote VB cord-300848-0igfcixy 27 13 direct direct JJ cord-300848-0igfcixy 27 14 damage damage NN cord-300848-0igfcixy 27 15 to to IN cord-300848-0igfcixy 27 16 kidney kidney NN cord-300848-0igfcixy 27 17 tissue tissue NN cord-300848-0igfcixy 27 18 in in IN cord-300848-0igfcixy 27 19 addition addition NN cord-300848-0igfcixy 27 20 to to IN cord-300848-0igfcixy 27 21 classical classical JJ cord-300848-0igfcixy 27 22 critical critical JJ cord-300848-0igfcixy 27 23 illness illness NN cord-300848-0igfcixy 27 24 - - HYPH cord-300848-0igfcixy 27 25 associated associate VBN cord-300848-0igfcixy 27 26 acute acute JJ cord-300848-0igfcixy 27 27 kidney kidney NN cord-300848-0igfcixy 27 28 injury injury NN cord-300848-0igfcixy 27 29 . . . cord-300848-0igfcixy 28 1 This this DT cord-300848-0igfcixy 28 2 puts put VBZ cord-300848-0igfcixy 28 3 SARS SARS NNP cord-300848-0igfcixy 28 4 - - HYPH cord-300848-0igfcixy 28 5 CoV-2 CoV-2 NNP cord-300848-0igfcixy 28 6 in in IN cord-300848-0igfcixy 28 7 an an DT cord-300848-0igfcixy 28 8 expanding expand VBG cord-300848-0igfcixy 28 9 list list NN cord-300848-0igfcixy 28 10 of of IN cord-300848-0igfcixy 28 11 other other JJ cord-300848-0igfcixy 28 12 viruses virus NNS cord-300848-0igfcixy 28 13 with with IN cord-300848-0igfcixy 28 14 proven prove VBN cord-300848-0igfcixy 28 15 kidney kidney NN cord-300848-0igfcixy 28 16 tropism tropism NN cord-300848-0igfcixy 28 17 , , , cord-300848-0igfcixy 28 18 including include VBG cord-300848-0igfcixy 28 19 hantavirus hantavirus NN cord-300848-0igfcixy 28 20 [ [ -LRB- cord-300848-0igfcixy 28 21 14 14 CD cord-300848-0igfcixy 28 22 ] ] -RRB- cord-300848-0igfcixy 28 23 , , , cord-300848-0igfcixy 28 24 the the DT cord-300848-0igfcixy 28 25 Middle Middle NNP cord-300848-0igfcixy 28 26 East East NNP cord-300848-0igfcixy 28 27 respiratory respiratory JJ cord-300848-0igfcixy 28 28 syndrome syndrome NN cord-300848-0igfcixy 28 29 coronavirus coronavirus NN cord-300848-0igfcixy 28 30 [ [ -LRB- cord-300848-0igfcixy 28 31 15 15 CD cord-300848-0igfcixy 28 32 ] ] -RRB- cord-300848-0igfcixy 28 33 , , , cord-300848-0igfcixy 28 34 polyomavirus polyomavirus NNP cord-300848-0igfcixy 28 35 ( ( -LRB- cord-300848-0igfcixy 28 36 polyomavirus polyomavirus NNP cord-300848-0igfcixy 28 37 - - HYPH cord-300848-0igfcixy 28 38 associated associate VBN cord-300848-0igfcixy 28 39 nephropathy nephropathy NN cord-300848-0igfcixy 28 40 ) ) -RRB- cord-300848-0igfcixy 28 41 [ [ -LRB- cord-300848-0igfcixy 28 42 16 16 CD cord-300848-0igfcixy 28 43 ] ] -RRB- cord-300848-0igfcixy 28 44 and and CC cord-300848-0igfcixy 28 45 the the DT cord-300848-0igfcixy 28 46 human human JJ cord-300848-0igfcixy 28 47 immunodeficiency immunodeficiency NN cord-300848-0igfcixy 28 48 virus virus NN cord-300848-0igfcixy 28 49 ( ( -LRB- cord-300848-0igfcixy 28 50 HIV HIV NNP cord-300848-0igfcixy 28 51 - - HYPH cord-300848-0igfcixy 28 52 associated associate VBN cord-300848-0igfcixy 28 53 nephropathy nephropathy NN cord-300848-0igfcixy 28 54 ) ) -RRB- cord-300848-0igfcixy 28 55 [ [ -LRB- cord-300848-0igfcixy 28 56 17 17 CD cord-300848-0igfcixy 28 57 ] ] -RRB- cord-300848-0igfcixy 28 58 . . . cord-300848-0igfcixy 29 1 In in IN cord-300848-0igfcixy 29 2 analogy analogy NN cord-300848-0igfcixy 29 3 , , , cord-300848-0igfcixy 29 4 we -PRON- PRP cord-300848-0igfcixy 29 5 propose propose VBP cord-300848-0igfcixy 29 6 to to TO cord-300848-0igfcixy 29 7 use use VB cord-300848-0igfcixy 29 8 the the DT cord-300848-0igfcixy 29 9 term term NN cord-300848-0igfcixy 29 10 coronavirus coronavirus NN cord-300848-0igfcixy 29 11 - - HYPH cord-300848-0igfcixy 29 12 associated associate VBN cord-300848-0igfcixy 29 13 nephropathy nephropathy NN cord-300848-0igfcixy 29 14 ( ( -LRB- cord-300848-0igfcixy 29 15 COVAN COVAN NNP cord-300848-0igfcixy 29 16 ; ; : cord-300848-0igfcixy 29 17 Figure figure NN cord-300848-0igfcixy 29 18 1 1 CD cord-300848-0igfcixy 29 19 ) ) -RRB- cord-300848-0igfcixy 29 20 . . . cord-300848-0igfcixy 30 1 Our -PRON- PRP$ cord-300848-0igfcixy 30 2 understanding understanding NN cord-300848-0igfcixy 30 3 of of IN cord-300848-0igfcixy 30 4 the the DT cord-300848-0igfcixy 30 5 clinical clinical JJ cord-300848-0igfcixy 30 6 picture picture NN cord-300848-0igfcixy 30 7 of of IN cord-300848-0igfcixy 30 8 COVAN COVAN NNP cord-300848-0igfcixy 30 9 remains remain VBZ cord-300848-0igfcixy 30 10 patchy patchy JJ cord-300848-0igfcixy 30 11 . . . cord-300848-0igfcixy 31 1 Correlation correlation NN cord-300848-0igfcixy 31 2 between between IN cord-300848-0igfcixy 31 3 histology histology NN cord-300848-0igfcixy 31 4 and and CC cord-300848-0igfcixy 31 5 functional functional JJ cord-300848-0igfcixy 31 6 findings finding NNS cord-300848-0igfcixy 31 7 is be VBZ cord-300848-0igfcixy 31 8 mostly mostly RB cord-300848-0igfcixy 31 9 lacking lacking JJ cord-300848-0igfcixy 31 10 . . . cord-300848-0igfcixy 32 1 In in IN cord-300848-0igfcixy 32 2 the the DT cord-300848-0igfcixy 32 3 abovementioned abovementioned JJ cord-300848-0igfcixy 32 4 autopsy autopsy JJ cord-300848-0igfcixy 32 5 studies study NNS cord-300848-0igfcixy 32 6 , , , cord-300848-0igfcixy 32 7 urinalysis urinalysis NN cord-300848-0igfcixy 32 8 was be VBD cord-300848-0igfcixy 32 9 available available JJ cord-300848-0igfcixy 32 10 in in IN cord-300848-0igfcixy 32 11 only only RB cord-300848-0igfcixy 32 12 a a DT cord-300848-0igfcixy 32 13 minority minority NN cord-300848-0igfcixy 32 14 of of IN cord-300848-0igfcixy 32 15 patients patient NNS cord-300848-0igfcixy 32 16 [ [ -LRB- cord-300848-0igfcixy 32 17 9 9 CD cord-300848-0igfcixy 32 18 , , , cord-300848-0igfcixy 32 19 13 13 CD cord-300848-0igfcixy 32 20 ] ] -RRB- cord-300848-0igfcixy 32 21 . . . cord-300848-0igfcixy 33 1 Moreover moreover RB cord-300848-0igfcixy 33 2 , , , cord-300848-0igfcixy 33 3 these these DT cord-300848-0igfcixy 33 4 biopsy biopsy NN cord-300848-0igfcixy 33 5 data datum NNS cord-300848-0igfcixy 33 6 originate originate VBP cord-300848-0igfcixy 33 7 from from IN cord-300848-0igfcixy 33 8 a a DT cord-300848-0igfcixy 33 9 highly highly RB cord-300848-0igfcixy 33 10 selected select VBN cord-300848-0igfcixy 33 11 group group NN cord-300848-0igfcixy 33 12 of of IN cord-300848-0igfcixy 33 13 deceased deceased JJ cord-300848-0igfcixy 33 14 patients patient NNS cord-300848-0igfcixy 33 15 , , , cord-300848-0igfcixy 33 16 after after IN cord-300848-0igfcixy 33 17 a a DT cord-300848-0igfcixy 33 18 period period NN cord-300848-0igfcixy 33 19 of of IN cord-300848-0igfcixy 33 20 critical critical JJ cord-300848-0igfcixy 33 21 illness illness NN cord-300848-0igfcixy 33 22 . . . cord-300848-0igfcixy 34 1 To to IN cord-300848-0igfcixy 34 2 date date NN cord-300848-0igfcixy 34 3 , , , cord-300848-0igfcixy 34 4 kidney kidney NN cord-300848-0igfcixy 34 5 histology histology NN cord-300848-0igfcixy 34 6 of of IN cord-300848-0igfcixy 34 7 COVID-19 covid-19 JJ cord-300848-0igfcixy 34 8 patients patient NNS cord-300848-0igfcixy 34 9 with with IN cord-300848-0igfcixy 34 10 a a DT cord-300848-0igfcixy 34 11 less less RBR cord-300848-0igfcixy 34 12 severe severe JJ cord-300848-0igfcixy 34 13 clinical clinical JJ cord-300848-0igfcixy 34 14 course course NN cord-300848-0igfcixy 34 15 has have VBZ cord-300848-0igfcixy 34 16 not not RB cord-300848-0igfcixy 34 17 been be VBN cord-300848-0igfcixy 34 18 reported report VBN cord-300848-0igfcixy 34 19 . . . cord-300848-0igfcixy 35 1 Clinical clinical JJ cord-300848-0igfcixy 35 2 case case NN cord-300848-0igfcixy 35 3 series series NN cord-300848-0igfcixy 35 4 from from IN cord-300848-0igfcixy 35 5 different different JJ cord-300848-0igfcixy 35 6 viral viral JJ cord-300848-0igfcixy 35 7 hotspots hotspot NNS cord-300848-0igfcixy 35 8 can can MD cord-300848-0igfcixy 35 9 partly partly RB cord-300848-0igfcixy 35 10 fill fill VB cord-300848-0igfcixy 35 11 this this DT cord-300848-0igfcixy 35 12 gap gap NN cord-300848-0igfcixy 35 13 . . . cord-300848-0igfcixy 36 1 Early early JJ cord-300848-0igfcixy 36 2 reports report NNS cord-300848-0igfcixy 36 3 , , , cord-300848-0igfcixy 36 4 although although IN cord-300848-0igfcixy 36 5 of of IN cord-300848-0igfcixy 36 6 great great JJ cord-300848-0igfcixy 36 7 importance importance NN cord-300848-0igfcixy 36 8 to to TO cord-300848-0igfcixy 36 9 alert alert VB cord-300848-0igfcixy 36 10 the the DT cord-300848-0igfcixy 36 11 world world NN cord-300848-0igfcixy 36 12 of of IN cord-300848-0igfcixy 36 13 trouble trouble NN cord-300848-0igfcixy 36 14 ahead ahead RB cord-300848-0igfcixy 36 15 , , , cord-300848-0igfcixy 36 16 were be VBD cord-300848-0igfcixy 36 17 hampered hamper VBN cord-300848-0igfcixy 36 18 by by IN cord-300848-0igfcixy 36 19 a a DT cord-300848-0igfcixy 36 20 number number NN cord-300848-0igfcixy 36 21 of of IN cord-300848-0igfcixy 36 22 drawbacks drawback NNS cord-300848-0igfcixy 36 23 , , , cord-300848-0igfcixy 36 24 i.e. i.e. FW cord-300848-0igfcixy 36 25 patient patient JJ cord-300848-0igfcixy 36 26 selection selection NN cord-300848-0igfcixy 36 27 with with IN cord-300848-0igfcixy 36 28 overrepresentation overrepresentation NN cord-300848-0igfcixy 36 29 of of IN cord-300848-0igfcixy 36 30 critically critically RB cord-300848-0igfcixy 36 31 ill ill JJ cord-300848-0igfcixy 36 32 patients patient NNS cord-300848-0igfcixy 36 33 , , , cord-300848-0igfcixy 36 34 as as RB cord-300848-0igfcixy 36 35 well well RB cord-300848-0igfcixy 36 36 as as IN cord-300848-0igfcixy 36 37 retrospective retrospective JJ cord-300848-0igfcixy 36 38 data data NN cord-300848-0igfcixy 36 39 collection collection NN cord-300848-0igfcixy 36 40 [ [ -LRB- cord-300848-0igfcixy 36 41 18 18 CD cord-300848-0igfcixy 36 42 , , , cord-300848-0igfcixy 36 43 19 19 CD cord-300848-0igfcixy 36 44 ] ] -RRB- cord-300848-0igfcixy 36 45 . . . cord-300848-0igfcixy 37 1 The the DT cord-300848-0igfcixy 37 2 latter latter JJ cord-300848-0igfcixy 37 3 is be VBZ cord-300848-0igfcixy 37 4 of of IN cord-300848-0igfcixy 37 5 importance importance NN cord-300848-0igfcixy 37 6 , , , cord-300848-0igfcixy 37 7 as as IN cord-300848-0igfcixy 37 8 urinalysis urinalysis NN cord-300848-0igfcixy 37 9 may may MD cord-300848-0igfcixy 37 10 not not RB cord-300848-0igfcixy 37 11 be be VB cord-300848-0igfcixy 37 12 routinely routinely RB cord-300848-0igfcixy 37 13 ( ( -LRB- cord-300848-0igfcixy 37 14 nor nor CC cord-300848-0igfcixy 37 15 be be VB cord-300848-0igfcixy 37 16 repeatedly repeatedly RB cord-300848-0igfcixy 37 17 ) ) -RRB- cord-300848-0igfcixy 37 18 performed perform VBN cord-300848-0igfcixy 37 19 in in IN cord-300848-0igfcixy 37 20 patients patient NNS cord-300848-0igfcixy 37 21 with with IN cord-300848-0igfcixy 37 22 predominantly predominantly RB cord-300848-0igfcixy 37 23 respiratory respiratory JJ cord-300848-0igfcixy 37 24 symptoms symptom NNS cord-300848-0igfcixy 37 25 . . . cord-300848-0igfcixy 38 1 Two two CD cord-300848-0igfcixy 38 2 reports report NNS cord-300848-0igfcixy 38 3 from from IN cord-300848-0igfcixy 38 4 the the DT cord-300848-0igfcixy 38 5 same same JJ cord-300848-0igfcixy 38 6 group group NN cord-300848-0igfcixy 38 7 ( ( -LRB- cord-300848-0igfcixy 38 8 Tongji Tongji NNP cord-300848-0igfcixy 38 9 University University NNP cord-300848-0igfcixy 38 10 , , , cord-300848-0igfcixy 38 11 Wuhan Wuhan NNP cord-300848-0igfcixy 38 12 ) ) -RRB- cord-300848-0igfcixy 38 13 focused focus VBD cord-300848-0igfcixy 38 14 on on IN cord-300848-0igfcixy 38 15 markers marker NNS cord-300848-0igfcixy 38 16 of of IN cord-300848-0igfcixy 38 17 kidney kidney NN cord-300848-0igfcixy 38 18 function function NN cord-300848-0igfcixy 38 19 [ [ -LRB- cord-300848-0igfcixy 38 20 20 20 CD cord-300848-0igfcixy 38 21 , , , cord-300848-0igfcixy 38 22 21 21 CD cord-300848-0igfcixy 38 23 ] ] -RRB- cord-300848-0igfcixy 38 24 . . . cord-300848-0igfcixy 39 1 They -PRON- PRP cord-300848-0igfcixy 39 2 performed perform VBD cord-300848-0igfcixy 39 3 a a DT cord-300848-0igfcixy 39 4 prospective prospective JJ cord-300848-0igfcixy 39 5 cohort cohort NN cord-300848-0igfcixy 39 6 study study NN cord-300848-0igfcixy 39 7 in in IN cord-300848-0igfcixy 39 8 701 701 CD cord-300848-0igfcixy 39 9 patients patient NNS cord-300848-0igfcixy 39 10 , , , cord-300848-0igfcixy 39 11 admitted admit VBD cord-300848-0igfcixy 39 12 to to IN cord-300848-0igfcixy 39 13 a a DT cord-300848-0igfcixy 39 14 designated designated JJ cord-300848-0igfcixy 39 15 tertiary tertiary JJ cord-300848-0igfcixy 39 16 care care NN cord-300848-0igfcixy 39 17 hospital hospital NN cord-300848-0igfcixy 39 18 . . . cord-300848-0igfcixy 40 1 Of of IN cord-300848-0igfcixy 40 2 these these DT cord-300848-0igfcixy 40 3 , , , cord-300848-0igfcixy 40 4 5.1 5.1 CD cord-300848-0igfcixy 40 5 % % NN cord-300848-0igfcixy 40 6 developed develop VBD cord-300848-0igfcixy 40 7 AKI AKI NNP cord-300848-0igfcixy 40 8 . . . cord-300848-0igfcixy 41 1 More More JJR cord-300848-0igfcixy 41 2 than than IN cord-300848-0igfcixy 41 3 40 40 CD cord-300848-0igfcixy 41 4 % % NN cord-300848-0igfcixy 41 5 of of IN cord-300848-0igfcixy 41 6 all all DT cord-300848-0igfcixy 41 7 patients patient NNS cord-300848-0igfcixy 41 8 had have VBD cord-300848-0igfcixy 41 9 proteinuria proteinuria NN cord-300848-0igfcixy 41 10 and and CC cord-300848-0igfcixy 41 11 $ $ $ cord-300848-0igfcixy 41 12 25 25 CD cord-300848-0igfcixy 41 13 % % NN cord-300848-0igfcixy 41 14 had have VBD cord-300848-0igfcixy 41 15 haematuria haematuria NNS cord-300848-0igfcixy 41 16 . . . cord-300848-0igfcixy 42 1 Of of IN cord-300848-0igfcixy 42 2 note note NN cord-300848-0igfcixy 42 3 , , , cord-300848-0igfcixy 42 4 despite despite IN cord-300848-0igfcixy 42 5 the the DT cord-300848-0igfcixy 42 6 fact fact NN cord-300848-0igfcixy 42 7 that that IN cord-300848-0igfcixy 42 8 this this DT cord-300848-0igfcixy 42 9 was be VBD cord-300848-0igfcixy 42 10 a a DT cord-300848-0igfcixy 42 11 prospective prospective JJ cord-300848-0igfcixy 42 12 study study NN cord-300848-0igfcixy 42 13 , , , cord-300848-0igfcixy 42 14 missing miss VBG cord-300848-0igfcixy 42 15 data datum NNS cord-300848-0igfcixy 42 16 are be VBP cord-300848-0igfcixy 42 17 nonnegligible nonnegligible JJ cord-300848-0igfcixy 42 18 . . . cord-300848-0igfcixy 43 1 Proteinuria Proteinuria NNP cord-300848-0igfcixy 43 2 and and CC cord-300848-0igfcixy 43 3 haematuria haematuria NNS cord-300848-0igfcixy 43 4 were be VBD cord-300848-0igfcixy 43 5 measured measure VBN cord-300848-0igfcixy 43 6 in in IN cord-300848-0igfcixy 43 7 442 442 CD cord-300848-0igfcixy 43 8 of of IN cord-300848-0igfcixy 43 9 the the DT cord-300848-0igfcixy 43 10 701 701 CD cord-300848-0igfcixy 43 11 included include VBD cord-300848-0igfcixy 43 12 patients patient NNS cord-300848-0igfcixy 43 13 ( ( -LRB- cord-300848-0igfcixy 43 14 37 37 CD cord-300848-0igfcixy 43 15 % % NN cord-300848-0igfcixy 43 16 missing miss VBG cord-300848-0igfcixy 43 17 data datum NNS cord-300848-0igfcixy 43 18 ) ) -RRB- cord-300848-0igfcixy 43 19 [ [ -LRB- cord-300848-0igfcixy 43 20 21 21 CD cord-300848-0igfcixy 43 21 ] ] -RRB- cord-300848-0igfcixy 43 22 . . . cord-300848-0igfcixy 44 1 They -PRON- PRP cord-300848-0igfcixy 44 2 also also RB cord-300848-0igfcixy 44 3 performed perform VBD cord-300848-0igfcixy 44 4 a a DT cord-300848-0igfcixy 44 5 retrospective retrospective JJ cord-300848-0igfcixy 44 6 study study NN cord-300848-0igfcixy 44 7 in in IN cord-300848-0igfcixy 44 8 467 467 CD cord-300848-0igfcixy 44 9 patients patient NNS cord-300848-0igfcixy 44 10 , , , cord-300848-0igfcixy 44 11 of of IN cord-300848-0igfcixy 44 12 which which WDT cord-300848-0igfcixy 44 13 333 333 CD cord-300848-0igfcixy 44 14 patients patient NNS cord-300848-0igfcixy 44 15 had have VBD cord-300848-0igfcixy 44 16 dipstick dipstick NN cord-300848-0igfcixy 44 17 analysis analysis NN cord-300848-0igfcixy 44 18 upon upon IN cord-300848-0igfcixy 44 19 submission submission NN cord-300848-0igfcixy 44 20 . . . cord-300848-0igfcixy 45 1 Noteworthy noteworthy JJ cord-300848-0igfcixy 45 2 , , , cord-300848-0igfcixy 45 3 254/333 254/333 NNP cord-300848-0igfcixy 45 4 ( ( -LRB- cord-300848-0igfcixy 45 5 76 76 CD cord-300848-0igfcixy 45 6 % % NN cord-300848-0igfcixy 45 7 ) ) -RRB- cord-300848-0igfcixy 46 1 patients patient NNS cord-300848-0igfcixy 46 2 were be VBD cord-300848-0igfcixy 46 3 also also RB cord-300848-0igfcixy 46 4 included include VBN cord-300848-0igfcixy 46 5 in in IN cord-300848-0igfcixy 46 6 the the DT cord-300848-0igfcixy 46 7 first first JJ cord-300848-0igfcixy 46 8 ( ( -LRB- cord-300848-0igfcixy 46 9 prospective prospective JJ cord-300848-0igfcixy 46 10 ) ) -RRB- cord-300848-0igfcixy 46 11 study study NN cord-300848-0igfcixy 46 12 cohort cohort NN cord-300848-0igfcixy 46 13 . . . cord-300848-0igfcixy 47 1 In in IN cord-300848-0igfcixy 47 2 the the DT cord-300848-0igfcixy 47 3 retrospective retrospective JJ cord-300848-0igfcixy 47 4 cohort cohort NN cord-300848-0igfcixy 47 5 , , , cord-300848-0igfcixy 47 6 10.5 10.5 CD cord-300848-0igfcixy 47 7 % % NN cord-300848-0igfcixy 47 8 developed develop VBD cord-300848-0igfcixy 47 9 AKI AKI NNP cord-300848-0igfcixy 47 10 , , , cord-300848-0igfcixy 47 11 66 66 CD cord-300848-0igfcixy 47 12 % % NN cord-300848-0igfcixy 47 13 had have VBD cord-300848-0igfcixy 47 14 proteinuria proteinuria NN cord-300848-0igfcixy 47 15 and and CC cord-300848-0igfcixy 47 16 42 42 CD cord-300848-0igfcixy 47 17 % % NN cord-300848-0igfcixy 47 18 had have VBD cord-300848-0igfcixy 47 19 haematuria haematuria NNS cord-300848-0igfcixy 47 20 [ [ -LRB- cord-300848-0igfcixy 47 21 20 20 CD cord-300848-0igfcixy 47 22 ] ] -RRB- cord-300848-0igfcixy 47 23 . . . cord-300848-0igfcixy 48 1 Of of IN cord-300848-0igfcixy 48 2 5449 5449 CD cord-300848-0igfcixy 48 3 patients patient NNS cord-300848-0igfcixy 48 4 with with IN cord-300848-0igfcixy 48 5 COVID-19 COVID-19 NNP cord-300848-0igfcixy 48 6 admitted admit VBN cord-300848-0igfcixy 48 7 to to IN cord-300848-0igfcixy 48 8 13 13 CD cord-300848-0igfcixy 48 9 academic academic JJ cord-300848-0igfcixy 48 10 and and CC cord-300848-0igfcixy 48 11 community community NN cord-300848-0igfcixy 48 12 hospitals hospital NNS cord-300848-0igfcixy 48 13 in in IN cord-300848-0igfcixy 48 14 metropolitan metropolitan JJ cord-300848-0igfcixy 48 15 New New NNP cord-300848-0igfcixy 48 16 York York NNP cord-300848-0igfcixy 48 17 , , , cord-300848-0igfcixy 48 18 36.6 36.6 CD cord-300848-0igfcixy 48 19 % % NN cord-300848-0igfcixy 48 20 developed develop VBD cord-300848-0igfcixy 48 21 AKI AKI NNP cord-300848-0igfcixy 48 22 , , , cord-300848-0igfcixy 48 23 which which WDT cord-300848-0igfcixy 48 24 was be VBD cord-300848-0igfcixy 48 25 strongly strongly RB cord-300848-0igfcixy 48 26 associated associate VBN cord-300848-0igfcixy 48 27 with with IN cord-300848-0igfcixy 48 28 the the DT cord-300848-0igfcixy 48 29 need need NN cord-300848-0igfcixy 48 30 for for IN cord-300848-0igfcixy 48 31 mechanical mechanical JJ cord-300848-0igfcixy 48 32 ventilation ventilation NN cord-300848-0igfcixy 48 33 . . . cord-300848-0igfcixy 49 1 Urine urine NN cord-300848-0igfcixy 49 2 dipstick dipstick NN cord-300848-0igfcixy 49 3 studies study NNS cord-300848-0igfcixy 49 4 were be VBD cord-300848-0igfcixy 49 5 available available JJ cord-300848-0igfcixy 49 6 in in IN cord-300848-0igfcixy 49 7 one one CD cord-300848-0igfcixy 49 8 - - HYPH cord-300848-0igfcixy 49 9 third third NN cord-300848-0igfcixy 49 10 of of IN cord-300848-0igfcixy 49 11 the the DT cord-300848-0igfcixy 49 12 patients patient NNS cord-300848-0igfcixy 49 13 with with IN cord-300848-0igfcixy 49 14 AKI AKI NNP cord-300848-0igfcixy 49 15 and and CC cord-300848-0igfcixy 49 16 showed show VBD cord-300848-0igfcixy 49 17 > > NNP cord-300848-0igfcixy 49 18 1þ 1þ CD cord-300848-0igfcixy 49 19 haematuria haematuria NNP cord-300848-0igfcixy 49 20 in in IN cord-300848-0igfcixy 49 21 46 46 CD cord-300848-0igfcixy 49 22 % % NN cord-300848-0igfcixy 49 23 of of IN cord-300848-0igfcixy 49 24 patients patient NNS cord-300848-0igfcixy 49 25 and and CC cord-300848-0igfcixy 49 26 > > XX cord-300848-0igfcixy 49 27 1þ 1þ CD cord-300848-0igfcixy 49 28 proteinuria proteinuria NN cord-300848-0igfcixy 49 29 in in IN cord-300848-0igfcixy 49 30 26 26 CD cord-300848-0igfcixy 49 31 % % NN cord-300848-0igfcixy 49 32 [ [ -LRB- cord-300848-0igfcixy 49 33 22 22 CD cord-300848-0igfcixy 49 34 ] ] -RRB- cord-300848-0igfcixy 49 35 . . . cord-300848-0igfcixy 50 1 Together together RB cord-300848-0igfcixy 50 2 , , , cord-300848-0igfcixy 50 3 these these DT cord-300848-0igfcixy 50 4 data datum NNS cord-300848-0igfcixy 50 5 suggest suggest VBP cord-300848-0igfcixy 50 6 that that IN cord-300848-0igfcixy 50 7 the the DT cord-300848-0igfcixy 50 8 clinical clinical JJ cord-300848-0igfcixy 50 9 picture picture NN cord-300848-0igfcixy 50 10 of of IN cord-300848-0igfcixy 50 11 COVID-19-related covid-19-related JJ cord-300848-0igfcixy 50 12 kidney kidney NN cord-300848-0igfcixy 50 13 disease disease NN cord-300848-0igfcixy 50 14 is be VBZ cord-300848-0igfcixy 50 15 broader broad JJR cord-300848-0igfcixy 50 16 than than IN cord-300848-0igfcixy 50 17 an an DT cord-300848-0igfcixy 50 18 acute acute JJ cord-300848-0igfcixy 50 19 decrease decrease NN cord-300848-0igfcixy 50 20 in in IN cord-300848-0igfcixy 50 21 glomerular glomerular JJ cord-300848-0igfcixy 50 22 filtration filtration NN cord-300848-0igfcixy 50 23 rate rate NN cord-300848-0igfcixy 50 24 due due IN cord-300848-0igfcixy 50 25 to to IN cord-300848-0igfcixy 50 26 acute acute JJ cord-300848-0igfcixy 50 27 tubular tubular JJ cord-300848-0igfcixy 50 28 necrosis necrosis NN cord-300848-0igfcixy 50 29 . . . cord-300848-0igfcixy 51 1 In in IN cord-300848-0igfcixy 51 2 this this DT cord-300848-0igfcixy 51 3 issue issue NN cord-300848-0igfcixy 51 4 of of IN cord-300848-0igfcixy 51 5 Nephrology Nephrology NNP cord-300848-0igfcixy 51 6 Dialysis Dialysis NNP cord-300848-0igfcixy 51 7 Transplantation Transplantation NNP cord-300848-0igfcixy 51 8 , , , cord-300848-0igfcixy 51 9 data datum NNS cord-300848-0igfcixy 51 10 from from IN cord-300848-0igfcixy 51 11 a a DT cord-300848-0igfcixy 51 12 large large JJ cord-300848-0igfcixy 51 13 European european JJ cord-300848-0igfcixy 51 14 cohort cohort NN cord-300848-0igfcixy 51 15 study study NN cord-300848-0igfcixy 51 16 of of IN cord-300848-0igfcixy 51 17 patients patient NNS cord-300848-0igfcixy 51 18 with with IN cord-300848-0igfcixy 51 19 COVID-19 COVID-19 NNP cord-300848-0igfcixy 51 20 are be VBP cord-300848-0igfcixy 51 21 reported report VBN cord-300848-0igfcixy 51 22 [ [ -LRB- cord-300848-0igfcixy 51 23 3 3 CD cord-300848-0igfcixy 51 24 ] ] -RRB- cord-300848-0igfcixy 51 25 . . . cord-300848-0igfcixy 52 1 The the DT cord-300848-0igfcixy 52 2 Puerta Puerta NNP cord-300848-0igfcixy 52 3 de de NNP cord-300848-0igfcixy 52 4 Hierro Hierro NNP cord-300848-0igfcixy 52 5 Hospital Hospital NNP cord-300848-0igfcixy 52 6 is be VBZ cord-300848-0igfcixy 52 7 located locate VBN cord-300848-0igfcixy 52 8 in in IN cord-300848-0igfcixy 52 9 Madrid Madrid NNP cord-300848-0igfcixy 52 10 , , , cord-300848-0igfcixy 52 11 one one CD cord-300848-0igfcixy 52 12 of of IN cord-300848-0igfcixy 52 13 the the DT cord-300848-0igfcixy 52 14 European european JJ cord-300848-0igfcixy 52 15 regions region NNS cord-300848-0igfcixy 52 16 most most RBS cord-300848-0igfcixy 52 17 affected affect VBN cord-300848-0igfcixy 52 18 by by IN cord-300848-0igfcixy 52 19 COVID-19 COVID-19 NNP cord-300848-0igfcixy 52 20 . . . cord-300848-0igfcixy 53 1 Strengths strength NNS cord-300848-0igfcixy 53 2 of of IN cord-300848-0igfcixy 53 3 the the DT cord-300848-0igfcixy 53 4 cohort cohort NN cord-300848-0igfcixy 53 5 study study NN cord-300848-0igfcixy 53 6 are be VBP cord-300848-0igfcixy 53 7 standardized standardized JJ cord-300848-0igfcixy 53 8 data datum NNS cord-300848-0igfcixy 53 9 collection collection NN cord-300848-0igfcixy 53 10 at at IN cord-300848-0igfcixy 53 11 admission admission NN cord-300848-0igfcixy 53 12 and and CC cord-300848-0igfcixy 53 13 follow follow NN cord-300848-0igfcixy 53 14 - - HYPH cord-300848-0igfcixy 53 15 up up NN cord-300848-0igfcixy 53 16 , , , cord-300848-0igfcixy 53 17 inclusion inclusion NN cord-300848-0igfcixy 53 18 of of IN cord-300848-0igfcixy 53 19 all all DT cord-300848-0igfcixy 53 20 patients patient NNS cord-300848-0igfcixy 53 21 ( ( -LRB- cord-300848-0igfcixy 53 22 less less JJR cord-300848-0igfcixy 53 23 focus focus NN cord-300848-0igfcixy 53 24 on on IN cord-300848-0igfcixy 53 25 intensive intensive JJ cord-300848-0igfcixy 53 26 care care NN cord-300848-0igfcixy 53 27 unit unit NN cord-300848-0igfcixy 53 28 ) ) -RRB- cord-300848-0igfcixy 53 29 , , , cord-300848-0igfcixy 53 30 knowledge knowledge NN cord-300848-0igfcixy 53 31 of of IN cord-300848-0igfcixy 53 32 pre pre JJ cord-300848-0igfcixy 53 33 - - JJ cord-300848-0igfcixy 53 34 existent existent JJ cord-300848-0igfcixy 53 35 chronic chronic JJ cord-300848-0igfcixy 53 36 kidney kidney NN cord-300848-0igfcixy 53 37 disease disease NN cord-300848-0igfcixy 53 38 ( ( -LRB- cord-300848-0igfcixy 53 39 CKD CKD NNP cord-300848-0igfcixy 53 40 ) ) -RRB- cord-300848-0igfcixy 53 41 and and CC cord-300848-0igfcixy 53 42 availability availability NN cord-300848-0igfcixy 53 43 of of IN cord-300848-0igfcixy 53 44 spot spot NN cord-300848-0igfcixy 53 45 urine urine NN cord-300848-0igfcixy 53 46 samples sample NNS cord-300848-0igfcixy 53 47 . . . cord-300848-0igfcixy 54 1 A a DT cord-300848-0igfcixy 54 2 total total NN cord-300848-0igfcixy 54 3 of of IN cord-300848-0igfcixy 54 4 1603 1603 CD cord-300848-0igfcixy 54 5 patients patient NNS cord-300848-0igfcixy 54 6 were be VBD cord-300848-0igfcixy 54 7 included include VBN cord-300848-0igfcixy 54 8 . . . cord-300848-0igfcixy 55 1 About about RB cord-300848-0igfcixy 55 2 a a DT cord-300848-0igfcixy 55 3 fifth fifth NN cord-300848-0igfcixy 55 4 of of IN cord-300848-0igfcixy 55 5 hospitalized hospitalize VBN cord-300848-0igfcixy 55 6 patients patient NNS cord-300848-0igfcixy 55 7 had have VBD cord-300848-0igfcixy 55 8 elevated elevate VBN cord-300848-0igfcixy 55 9 creatinine creatinine NN cord-300848-0igfcixy 55 10 levels level NNS cord-300848-0igfcixy 55 11 upon upon IN cord-300848-0igfcixy 55 12 admission admission NN cord-300848-0igfcixy 55 13 . . . cord-300848-0igfcixy 56 1 Of of IN cord-300848-0igfcixy 56 2 these these DT cord-300848-0igfcixy 56 3 , , , cord-300848-0igfcixy 56 4 $ $ $ cord-300848-0igfcixy 56 5 40 40 CD cord-300848-0igfcixy 56 6 % % NN cord-300848-0igfcixy 56 7 were be VBD cord-300848-0igfcixy 56 8 known know VBN cord-300848-0igfcixy 56 9 to to TO cord-300848-0igfcixy 56 10 have have VB cord-300848-0igfcixy 56 11 pre pre JJ cord-300848-0igfcixy 56 12 - - JJ cord-300848-0igfcixy 56 13 existent existent JJ cord-300848-0igfcixy 56 14 CKD CKD NNP cord-300848-0igfcixy 56 15 . . . cord-300848-0igfcixy 57 1 Proteinuria Proteinuria NNP cord-300848-0igfcixy 57 2 was be VBD cord-300848-0igfcixy 57 3 found find VBN cord-300848-0igfcixy 57 4 in in IN cord-300848-0igfcixy 57 5 nearly nearly RB cord-300848-0igfcixy 57 6 40 40 CD cord-300848-0igfcixy 57 7 % % NN cord-300848-0igfcixy 57 8 , , , cord-300848-0igfcixy 57 9 and and CC cord-300848-0igfcixy 57 10 haematuria haematuria NN cord-300848-0igfcixy 57 11 in in IN cord-300848-0igfcixy 57 12 slightly slightly RB cord-300848-0igfcixy 57 13 over over IN cord-300848-0igfcixy 57 14 half half NN cord-300848-0igfcixy 57 15 of of IN cord-300848-0igfcixy 57 16 the the DT cord-300848-0igfcixy 57 17 patients patient NNS cord-300848-0igfcixy 57 18 . . . cord-300848-0igfcixy 58 1 Differences difference NNS cord-300848-0igfcixy 58 2 in in IN cord-300848-0igfcixy 58 3 the the DT cord-300848-0igfcixy 58 4 composition composition NN cord-300848-0igfcixy 58 5 of of IN cord-300848-0igfcixy 58 6 the the DT cord-300848-0igfcixy 58 7 cohorts cohort NNS cord-300848-0igfcixy 58 8 , , , cord-300848-0igfcixy 58 9 the the DT cord-300848-0igfcixy 58 10 different different JJ cord-300848-0igfcixy 58 11 genetic genetic JJ cord-300848-0igfcixy 58 12 backgrounds background NNS cord-300848-0igfcixy 58 13 ( ( -LRB- cord-300848-0igfcixy 58 14 Han Han NNP cord-300848-0igfcixy 58 15 Chinese Chinese NNP cord-300848-0igfcixy 58 16 versus versus IN cord-300848-0igfcixy 58 17 multiracial multiracial JJ cord-300848-0igfcixy 58 18 versus versus IN cord-300848-0igfcixy 58 19 Caucasian caucasian JJ cord-300848-0igfcixy 58 20 ) ) -RRB- cord-300848-0igfcixy 58 21 and and CC cord-300848-0igfcixy 58 22 differences difference NNS cord-300848-0igfcixy 58 23 in in IN cord-300848-0igfcixy 58 24 the the DT cord-300848-0igfcixy 58 25 organization organization NNP cord-300848-0igfcixy 58 26 of of IN cord-300848-0igfcixy 58 27 healthcare healthcare NNP cord-300848-0igfcixy 58 28 , , , cord-300848-0igfcixy 58 29 could could MD cord-300848-0igfcixy 58 30 all all RB cord-300848-0igfcixy 58 31 explain explain VB cord-300848-0igfcixy 58 32 why why WRB cord-300848-0igfcixy 58 33 the the DT cord-300848-0igfcixy 58 34 prevalence prevalence NN cord-300848-0igfcixy 58 35 of of IN cord-300848-0igfcixy 58 36 AKI AKI NNP cord-300848-0igfcixy 58 37 varied varied JJ cord-300848-0igfcixy 58 38 from from IN cord-300848-0igfcixy 58 39 5.1 5.1 CD cord-300848-0igfcixy 58 40 to to IN cord-300848-0igfcixy 58 41 36.6 36.6 CD cord-300848-0igfcixy 58 42 % % NN cord-300848-0igfcixy 58 43 . . . cord-300848-0igfcixy 59 1 Nevertheless nevertheless RB cord-300848-0igfcixy 59 2 , , , cord-300848-0igfcixy 59 3 the the DT cord-300848-0igfcixy 59 4 prevalence prevalence NN cord-300848-0igfcixy 59 5 of of IN cord-300848-0igfcixy 59 6 proteinuria proteinuria NN cord-300848-0igfcixy 59 7 and and CC cord-300848-0igfcixy 59 8 haematuria haematuria NN cord-300848-0igfcixy 59 9 in in IN cord-300848-0igfcixy 59 10 a a DT cord-300848-0igfcixy 59 11 significant significant JJ cord-300848-0igfcixy 59 12 proportion proportion NN cord-300848-0igfcixy 59 13 of of IN cord-300848-0igfcixy 59 14 patients patient NNS cord-300848-0igfcixy 59 15 is be VBZ cord-300848-0igfcixy 59 16 quite quite PDT cord-300848-0igfcixy 59 17 a a DT cord-300848-0igfcixy 59 18 common common JJ cord-300848-0igfcixy 59 19 finding finding NN cord-300848-0igfcixy 59 20 , , , cord-300848-0igfcixy 59 21 supporting support VBG cord-300848-0igfcixy 59 22 the the DT cord-300848-0igfcixy 59 23 existence existence NN cord-300848-0igfcixy 59 24 of of IN cord-300848-0igfcixy 59 25 COVAN COVAN NNP cord-300848-0igfcixy 59 26 as as IN cord-300848-0igfcixy 59 27 a a DT cord-300848-0igfcixy 59 28 separate separate JJ cord-300848-0igfcixy 59 29 disease disease NN cord-300848-0igfcixy 59 30 entity entity NN cord-300848-0igfcixy 59 31 . . . cord-300848-0igfcixy 60 1 The the DT cord-300848-0igfcixy 60 2 challenge challenge NN cord-300848-0igfcixy 60 3 for for IN cord-300848-0igfcixy 60 4 the the DT cord-300848-0igfcixy 60 5 nephrological nephrological JJ cord-300848-0igfcixy 60 6 community community NN cord-300848-0igfcixy 60 7 is be VBZ cord-300848-0igfcixy 60 8 to to TO cord-300848-0igfcixy 60 9 characterize characterize VB cord-300848-0igfcixy 60 10 the the DT cord-300848-0igfcixy 60 11 renal renal JJ cord-300848-0igfcixy 60 12 phenotype phenotype NN cord-300848-0igfcixy 60 13 of of IN cord-300848-0igfcixy 60 14 COVID-19 COVID-19 NNP cord-300848-0igfcixy 60 15 in in IN cord-300848-0igfcixy 60 16 more more JJR cord-300848-0igfcixy 60 17 detail detail NN cord-300848-0igfcixy 60 18 . . . cord-300848-0igfcixy 61 1 Relevant relevant JJ cord-300848-0igfcixy 61 2 questions question NNS cord-300848-0igfcixy 61 3 are be VBP cord-300848-0igfcixy 61 4 whether whether IN cord-300848-0igfcixy 61 5 the the DT cord-300848-0igfcixy 61 6 haematuria haematuria NN cord-300848-0igfcixy 61 7 is be VBZ cord-300848-0igfcixy 61 8 of of IN cord-300848-0igfcixy 61 9 glomerular glomerular JJ cord-300848-0igfcixy 61 10 or or CC cord-300848-0igfcixy 61 11 non non JJ cord-300848-0igfcixy 61 12 - - JJ cord-300848-0igfcixy 61 13 glomerular glomerular JJ cord-300848-0igfcixy 61 14 origin origin NN cord-300848-0igfcixy 61 15 and and CC cord-300848-0igfcixy 61 16 whether whether IN cord-300848-0igfcixy 61 17 the the DT cord-300848-0igfcixy 61 18 proteinuria proteinuria NN cord-300848-0igfcixy 61 19 is be VBZ cord-300848-0igfcixy 61 20 associated associate VBN cord-300848-0igfcixy 61 21 with with IN cord-300848-0igfcixy 61 22 haematuria haematuria NNS cord-300848-0igfcixy 61 23 . . . cord-300848-0igfcixy 62 1 In in IN cord-300848-0igfcixy 62 2 addition addition NN cord-300848-0igfcixy 62 3 , , , cord-300848-0igfcixy 62 4 the the DT cord-300848-0igfcixy 62 5 type type NN cord-300848-0igfcixy 62 6 of of IN cord-300848-0igfcixy 62 7 proteins protein NNS cord-300848-0igfcixy 62 8 that that WDT cord-300848-0igfcixy 62 9 are be VBP cord-300848-0igfcixy 62 10 predominantly predominantly RB cord-300848-0igfcixy 62 11 present present JJ cord-300848-0igfcixy 62 12 in in IN cord-300848-0igfcixy 62 13 the the DT cord-300848-0igfcixy 62 14 urine urine NN cord-300848-0igfcixy 62 15 should should MD cord-300848-0igfcixy 62 16 be be VB cord-300848-0igfcixy 62 17 assessed assess VBN cord-300848-0igfcixy 62 18 . . . cord-300848-0igfcixy 63 1 Kidney kidney NN cord-300848-0igfcixy 63 2 biopsies biopsy NNS cord-300848-0igfcixy 63 3 could could MD cord-300848-0igfcixy 63 4 be be VB cord-300848-0igfcixy 63 5 helpful helpful JJ cord-300848-0igfcixy 63 6 to to TO cord-300848-0igfcixy 63 7 correlate correlate VB cord-300848-0igfcixy 63 8 laboratory laboratory NN cord-300848-0igfcixy 63 9 findings finding NNS cord-300848-0igfcixy 63 10 to to IN cord-300848-0igfcixy 63 11 histological histological JJ cord-300848-0igfcixy 63 12 changes change NNS cord-300848-0igfcixy 63 13 as as IN cord-300848-0igfcixy 63 14 evaluated evaluate VBN cord-300848-0igfcixy 63 15 by by IN cord-300848-0igfcixy 63 16 light light JJ cord-300848-0igfcixy 63 17 microscopy microscopy NN cord-300848-0igfcixy 63 18 , , , cord-300848-0igfcixy 63 19 immunofluorescence immunofluorescence NN cord-300848-0igfcixy 63 20 and and CC cord-300848-0igfcixy 63 21 electron electron NN cord-300848-0igfcixy 63 22 microscopy microscopy NN cord-300848-0igfcixy 63 23 . . . cord-300848-0igfcixy 64 1 A a DT cord-300848-0igfcixy 64 2 next next JJ cord-300848-0igfcixy 64 3 important important JJ cord-300848-0igfcixy 64 4 question question NN cord-300848-0igfcixy 64 5 is be VBZ cord-300848-0igfcixy 64 6 what what WP cord-300848-0igfcixy 64 7 COVAN COVAN NNP cord-300848-0igfcixy 64 8 portents portent NNS cord-300848-0igfcixy 64 9 in in IN cord-300848-0igfcixy 64 10 the the DT cord-300848-0igfcixy 64 11 short short JJ cord-300848-0igfcixy 64 12 and and CC cord-300848-0igfcixy 64 13 the the DT cord-300848-0igfcixy 64 14 long long JJ cord-300848-0igfcixy 64 15 term term NN cord-300848-0igfcixy 64 16 . . . cord-300848-0igfcixy 65 1 Portolés Portolés NNP cord-300848-0igfcixy 65 2 et et IN cord-300848-0igfcixy 65 3 al al NNP cord-300848-0igfcixy 65 4 . . . cord-300848-0igfcixy 66 1 found find VBD cord-300848-0igfcixy 66 2 a a DT cord-300848-0igfcixy 66 3 clear clear JJ cord-300848-0igfcixy 66 4 association association NN cord-300848-0igfcixy 66 5 between between IN cord-300848-0igfcixy 66 6 loss loss NN cord-300848-0igfcixy 66 7 of of IN cord-300848-0igfcixy 66 8 kidney kidney NN cord-300848-0igfcixy 66 9 function function NN cord-300848-0igfcixy 66 10 and and CC cord-300848-0igfcixy 66 11 an an DT cord-300848-0igfcixy 66 12 increase increase NN cord-300848-0igfcixy 66 13 in in IN cord-300848-0igfcixy 66 14 short short JJ cord-300848-0igfcixy 66 15 - - HYPH cord-300848-0igfcixy 66 16 term term NN cord-300848-0igfcixy 66 17 mortality mortality NN cord-300848-0igfcixy 66 18 [ [ -LRB- cord-300848-0igfcixy 66 19 3 3 CD cord-300848-0igfcixy 66 20 ] ] -RRB- cord-300848-0igfcixy 66 21 . . . cord-300848-0igfcixy 67 1 This this DT cord-300848-0igfcixy 67 2 is be VBZ cord-300848-0igfcixy 67 3 in in IN cord-300848-0igfcixy 67 4 line line NN cord-300848-0igfcixy 67 5 with with IN cord-300848-0igfcixy 67 6 the the DT cord-300848-0igfcixy 67 7 Wuhan Wuhan NNP cord-300848-0igfcixy 67 8 and and CC cord-300848-0igfcixy 67 9 New New NNP cord-300848-0igfcixy 67 10 York York NNP cord-300848-0igfcixy 67 11 data datum NNS cord-300848-0igfcixy 67 12 [ [ -LRB- cord-300848-0igfcixy 67 13 21 21 CD cord-300848-0igfcixy 67 14 , , , cord-300848-0igfcixy 67 15 22 22 CD cord-300848-0igfcixy 67 16 ] ] -RRB- cord-300848-0igfcixy 67 17 . . . cord-300848-0igfcixy 68 1 Such such JJ cord-300848-0igfcixy 68 2 associations association NNS cord-300848-0igfcixy 68 3 , , , cord-300848-0igfcixy 68 4 however however RB cord-300848-0igfcixy 68 5 , , , cord-300848-0igfcixy 68 6 are be VBP cord-300848-0igfcixy 68 7 not not RB cord-300848-0igfcixy 68 8 specific specific JJ cord-300848-0igfcixy 68 9 for for IN cord-300848-0igfcixy 68 10 COVID-19 COVID-19 NNP cord-300848-0igfcixy 68 11 . . . cord-300848-0igfcixy 69 1 Critical critical JJ cord-300848-0igfcixy 69 2 illness illness NN cord-300848-0igfcixy 69 3 is be VBZ cord-300848-0igfcixy 69 4 associated associate VBN cord-300848-0igfcixy 69 5 with with IN cord-300848-0igfcixy 69 6 both both DT cord-300848-0igfcixy 69 7 poor poor JJ cord-300848-0igfcixy 69 8 outcomes outcome NNS cord-300848-0igfcixy 69 9 and and CC cord-300848-0igfcixy 69 10 risk risk NN cord-300848-0igfcixy 69 11 of of IN cord-300848-0igfcixy 69 12 AKI AKI NNP cord-300848-0igfcixy 69 13 , , , cord-300848-0igfcixy 69 14 and and CC cord-300848-0igfcixy 69 15 it -PRON- PRP cord-300848-0igfcixy 69 16 is be VBZ cord-300848-0igfcixy 69 17 near near RB cord-300848-0igfcixy 69 18 - - HYPH cord-300848-0igfcixy 69 19 impossible impossible JJ cord-300848-0igfcixy 69 20 to to TO cord-300848-0igfcixy 69 21 disentangle disentangle VB cord-300848-0igfcixy 69 22 cause cause NN cord-300848-0igfcixy 69 23 and and CC cord-300848-0igfcixy 69 24 consequence consequence NN cord-300848-0igfcixy 69 25 . . . cord-300848-0igfcixy 70 1 Of of IN cord-300848-0igfcixy 70 2 greater great JJR cord-300848-0igfcixy 70 3 relevance relevance NN cord-300848-0igfcixy 70 4 is be VBZ cord-300848-0igfcixy 70 5 the the DT cord-300848-0igfcixy 70 6 observation observation NN cord-300848-0igfcixy 70 7 that that IN cord-300848-0igfcixy 70 8 new new JJ cord-300848-0igfcixy 70 9 - - HYPH cord-300848-0igfcixy 70 10 onset onset NN cord-300848-0igfcixy 70 11 haematuria haematuria NN cord-300848-0igfcixy 70 12 is be VBZ cord-300848-0igfcixy 70 13 associated associate VBN cord-300848-0igfcixy 70 14 with with IN cord-300848-0igfcixy 70 15 higher high JJR cord-300848-0igfcixy 70 16 mortality mortality NN cord-300848-0igfcixy 70 17 . . . cord-300848-0igfcixy 71 1 The the DT cord-300848-0igfcixy 71 2 Tongji Tongji NNP cord-300848-0igfcixy 71 3 data datum NNS cord-300848-0igfcixy 71 4 equally equally RB cord-300848-0igfcixy 71 5 show show VBP cord-300848-0igfcixy 71 6 that that IN cord-300848-0igfcixy 71 7 haematuria haematuria NN cord-300848-0igfcixy 71 8 and and CC cord-300848-0igfcixy 71 9 proteinuria proteinuria NN cord-300848-0igfcixy 71 10 predict predict VBP cord-300848-0igfcixy 71 11 short short JJ cord-300848-0igfcixy 71 12 - - HYPH cord-300848-0igfcixy 71 13 term term NN cord-300848-0igfcixy 71 14 mortality mortality NN cord-300848-0igfcixy 71 15 [ [ -LRB- cord-300848-0igfcixy 71 16 21 21 CD cord-300848-0igfcixy 71 17 ] ] -RRB- cord-300848-0igfcixy 71 18 . . . cord-300848-0igfcixy 72 1 It -PRON- PRP cord-300848-0igfcixy 72 2 is be VBZ cord-300848-0igfcixy 72 3 not not RB cord-300848-0igfcixy 72 4 yet yet RB cord-300848-0igfcixy 72 5 clear clear JJ cord-300848-0igfcixy 72 6 how how WRB cord-300848-0igfcixy 72 7 to to TO cord-300848-0igfcixy 72 8 understand understand VB cord-300848-0igfcixy 72 9 this this DT cord-300848-0igfcixy 72 10 observation observation NN cord-300848-0igfcixy 72 11 . . . cord-300848-0igfcixy 73 1 The the DT cord-300848-0igfcixy 73 2 number number NN cord-300848-0igfcixy 73 3 of of IN cord-300848-0igfcixy 73 4 patients patient NNS cord-300848-0igfcixy 73 5 diagnosed diagnose VBN cord-300848-0igfcixy 73 6 with with IN cord-300848-0igfcixy 73 7 haematuria haematuria NNP cord-300848-0igfcixy 73 8 is be VBZ cord-300848-0igfcixy 73 9 higher high JJR cord-300848-0igfcixy 73 10 than than IN cord-300848-0igfcixy 73 11 the the DT cord-300848-0igfcixy 73 12 number number NN cord-300848-0igfcixy 73 13 of of IN cord-300848-0igfcixy 73 14 patients patient NNS cord-300848-0igfcixy 73 15 experiencing experience VBG cord-300848-0igfcixy 73 16 loss loss NN cord-300848-0igfcixy 73 17 of of IN cord-300848-0igfcixy 73 18 glomerular glomerular JJ cord-300848-0igfcixy 73 19 filtration filtration NN cord-300848-0igfcixy 73 20 rate rate NN cord-300848-0igfcixy 73 21 . . . cord-300848-0igfcixy 74 1 Is be VBZ cord-300848-0igfcixy 74 2 haematuria haematuria NNP cord-300848-0igfcixy 74 3 a a DT cord-300848-0igfcixy 74 4 marker marker NN cord-300848-0igfcixy 74 5 of of IN cord-300848-0igfcixy 74 6 more more RBR cord-300848-0igfcixy 74 7 severe severe JJ cord-300848-0igfcixy 74 8 COVID-19 covid-19 NN cord-300848-0igfcixy 74 9 ( ( -LRB- cord-300848-0igfcixy 74 10 and and CC cord-300848-0igfcixy 74 11 need need NN cord-300848-0igfcixy 74 12 of of IN cord-300848-0igfcixy 74 13 urinary urinary JJ cord-300848-0igfcixy 74 14 catheter catheter NN cord-300848-0igfcixy 74 15 insertion insertion NN cord-300848-0igfcixy 74 16 ) ) -RRB- cord-300848-0igfcixy 74 17 , , , cord-300848-0igfcixy 74 18 or or CC cord-300848-0igfcixy 74 19 does do VBZ cord-300848-0igfcixy 74 20 this this DT cord-300848-0igfcixy 74 21 indicate indicate VB cord-300848-0igfcixy 74 22 a a DT cord-300848-0igfcixy 74 23 subgroup subgroup NN cord-300848-0igfcixy 74 24 of of IN cord-300848-0igfcixy 74 25 patients patient NNS cord-300848-0igfcixy 74 26 in in IN cord-300848-0igfcixy 74 27 which which WDT cord-300848-0igfcixy 74 28 kidney kidney NN cord-300848-0igfcixy 74 29 tropism tropism NN cord-300848-0igfcixy 74 30 , , , cord-300848-0igfcixy 74 31 resulting result VBG cord-300848-0igfcixy 74 32 in in IN cord-300848-0igfcixy 74 33 COVAN COVAN NNP cord-300848-0igfcixy 74 34 , , , cord-300848-0igfcixy 74 35 contributes contribute VBZ cord-300848-0igfcixy 74 36 to to IN cord-300848-0igfcixy 74 37 worse bad JJR cord-300848-0igfcixy 74 38 outcome outcome NN cord-300848-0igfcixy 74 39 ? ? . cord-300848-0igfcixy 75 1 As as IN cord-300848-0igfcixy 75 2 the the DT cord-300848-0igfcixy 75 3 pandemic pandemic NN cord-300848-0igfcixy 75 4 unfolds unfold VBZ cord-300848-0igfcixy 75 5 , , , cord-300848-0igfcixy 75 6 our -PRON- PRP$ cord-300848-0igfcixy 75 7 understanding understanding NN cord-300848-0igfcixy 75 8 of of IN cord-300848-0igfcixy 75 9 COVID-19 COVID-19 NNP cord-300848-0igfcixy 75 10 continues continue VBZ cord-300848-0igfcixy 75 11 to to TO cord-300848-0igfcixy 75 12 grow grow VB cord-300848-0igfcixy 75 13 . . . cord-300848-0igfcixy 76 1 The the DT cord-300848-0igfcixy 76 2 Madrid Madrid NNP cord-300848-0igfcixy 76 3 dataset dataset NN cord-300848-0igfcixy 76 4 provides provide VBZ cord-300848-0igfcixy 76 5 further further JJ cord-300848-0igfcixy 76 6 support support NN cord-300848-0igfcixy 76 7 for for IN cord-300848-0igfcixy 76 8 COVAN COVAN NNP cord-300848-0igfcixy 76 9 as as IN cord-300848-0igfcixy 76 10 part part NN cord-300848-0igfcixy 76 11 of of IN cord-300848-0igfcixy 76 12 the the DT cord-300848-0igfcixy 76 13 clinical clinical JJ cord-300848-0igfcixy 76 14 spectrum spectrum NN cord-300848-0igfcixy 76 15 . . . cord-300848-0igfcixy 77 1 What what WP cord-300848-0igfcixy 77 2 is be VBZ cord-300848-0igfcixy 77 3 not not RB cord-300848-0igfcixy 77 4 known know VBN cord-300848-0igfcixy 77 5 at at IN cord-300848-0igfcixy 77 6 this this DT cord-300848-0igfcixy 77 7 time time NN cord-300848-0igfcixy 77 8 is be VBZ cord-300848-0igfcixy 77 9 whether whether IN cord-300848-0igfcixy 77 10 this this DT cord-300848-0igfcixy 77 11 is be VBZ cord-300848-0igfcixy 77 12 a a DT cord-300848-0igfcixy 77 13 transient transient JJ cord-300848-0igfcixy 77 14 phenomenon phenomenon NN cord-300848-0igfcixy 77 15 without without IN cord-300848-0igfcixy 77 16 long long JJ cord-300848-0igfcixy 77 17 - - HYPH cord-300848-0igfcixy 77 18 term term NN cord-300848-0igfcixy 77 19 consequences consequence NNS cord-300848-0igfcixy 77 20 . . . cord-300848-0igfcixy 78 1 Will Will MD cord-300848-0igfcixy 78 2 kidney kidney NN cord-300848-0igfcixy 78 3 tropism tropism NN cord-300848-0igfcixy 78 4 of of IN cord-300848-0igfcixy 78 5 SARS SARS NNP cord-300848-0igfcixy 78 6 - - HYPH cord-300848-0igfcixy 78 7 CoV-2 CoV-2 NNP cord-300848-0igfcixy 78 8 result result NN cord-300848-0igfcixy 78 9 in in IN cord-300848-0igfcixy 78 10 an an DT cord-300848-0igfcixy 78 11 increased increase VBN cord-300848-0igfcixy 78 12 risk risk NN cord-300848-0igfcixy 78 13 for for IN cord-300848-0igfcixy 78 14 progressive progressive JJ cord-300848-0igfcixy 78 15 CKD CKD NNP cord-300848-0igfcixy 78 16 ? ? . cord-300848-0igfcixy 79 1 Ideally ideally RB cord-300848-0igfcixy 79 2 , , , cord-300848-0igfcixy 79 3 part part NN cord-300848-0igfcixy 79 4 of of IN cord-300848-0igfcixy 79 5 the the DT cord-300848-0igfcixy 79 6 Spanish spanish JJ cord-300848-0igfcixy 79 7 cohort cohort NN cord-300848-0igfcixy 79 8 will will MD cord-300848-0igfcixy 79 9 be be VB cord-300848-0igfcixy 79 10 followed follow VBN cord-300848-0igfcixy 79 11 over over IN cord-300848-0igfcixy 79 12 time time NN cord-300848-0igfcixy 79 13 . . . cord-300848-0igfcixy 80 1 Also also RB cord-300848-0igfcixy 80 2 , , , cord-300848-0igfcixy 80 3 we -PRON- PRP cord-300848-0igfcixy 80 4 do do VBP cord-300848-0igfcixy 80 5 not not RB cord-300848-0igfcixy 80 6 know know VB cord-300848-0igfcixy 80 7 whether whether IN cord-300848-0igfcixy 80 8 asymptomatic asymptomatic JJ cord-300848-0igfcixy 80 9 individuals individual NNS cord-300848-0igfcixy 80 10 infected infect VBN cord-300848-0igfcixy 80 11 by by IN cord-300848-0igfcixy 80 12 SARS SARS NNP cord-300848-0igfcixy 80 13 - - HYPH cord-300848-0igfcixy 80 14 CoV-2 CoV-2 NNP cord-300848-0igfcixy 80 15 , , , cord-300848-0igfcixy 80 16 or or CC cord-300848-0igfcixy 80 17 those those DT cord-300848-0igfcixy 80 18 with with IN cord-300848-0igfcixy 80 19 COVID-19 covid-19 JJ cord-300848-0igfcixy 80 20 and and CC cord-300848-0igfcixy 80 21 minor minor JJ cord-300848-0igfcixy 80 22 respiratory respiratory JJ cord-300848-0igfcixy 80 23 symptoms symptom NNS cord-300848-0igfcixy 80 24 , , , cord-300848-0igfcixy 80 25 will will MD cord-300848-0igfcixy 80 26 develop develop VB cord-300848-0igfcixy 80 27 COVAN COVAN NNP cord-300848-0igfcixy 80 28 that that WDT cord-300848-0igfcixy 80 29 is be VBZ cord-300848-0igfcixy 80 30 detectable detectable JJ cord-300848-0igfcixy 80 31 via via IN cord-300848-0igfcixy 80 32 urinary urinary JJ cord-300848-0igfcixy 80 33 indices index NNS cord-300848-0igfcixy 80 34 . . . cord-300848-0igfcixy 81 1 If if IN cord-300848-0igfcixy 81 2 this this DT cord-300848-0igfcixy 81 3 were be VBD cord-300848-0igfcixy 81 4 to to TO cord-300848-0igfcixy 81 5 be be VB cord-300848-0igfcixy 81 6 the the DT cord-300848-0igfcixy 81 7 case case NN cord-300848-0igfcixy 81 8 , , , cord-300848-0igfcixy 81 9 then then RB cord-300848-0igfcixy 81 10 unexplained unexplained JJ cord-300848-0igfcixy 81 11 haematuria haematuria NNS cord-300848-0igfcixy 81 12 and/or and/or CC cord-300848-0igfcixy 81 13 proteinuria proteinuria NN cord-300848-0igfcixy 81 14 should should MD cord-300848-0igfcixy 81 15 warrant warrant VB cord-300848-0igfcixy 81 16 testing testing NN cord-300848-0igfcixy 81 17 for for IN cord-300848-0igfcixy 81 18 COVID-19 COVID-19 NNP cord-300848-0igfcixy 81 19 . . . cord-300848-0igfcixy 82 1 We -PRON- PRP cord-300848-0igfcixy 82 2 believe believe VBP cord-300848-0igfcixy 82 3 the the DT cord-300848-0igfcixy 82 4 evidence evidence NN cord-300848-0igfcixy 82 5 is be VBZ cord-300848-0igfcixy 82 6 insufficient insufficient JJ cord-300848-0igfcixy 82 7 to to TO cord-300848-0igfcixy 82 8 draw draw VB cord-300848-0igfcixy 82 9 this this DT cord-300848-0igfcixy 82 10 conclusion conclusion NN cord-300848-0igfcixy 82 11 . . . cord-300848-0igfcixy 83 1 At at IN cord-300848-0igfcixy 83 2 the the DT cord-300848-0igfcixy 83 3 same same JJ cord-300848-0igfcixy 83 4 time time NN cord-300848-0igfcixy 83 5 , , , cord-300848-0igfcixy 83 6 we -PRON- PRP cord-300848-0igfcixy 83 7 believe believe VBP cord-300848-0igfcixy 83 8 the the DT cord-300848-0igfcixy 83 9 evidence evidence NN cord-300848-0igfcixy 83 10 is be VBZ cord-300848-0igfcixy 83 11 sufficient sufficient JJ cord-300848-0igfcixy 83 12 to to TO cord-300848-0igfcixy 83 13 consider consider VB cord-300848-0igfcixy 83 14 COVAN COVAN NNP cord-300848-0igfcixy 83 15 as as IN cord-300848-0igfcixy 83 16 part part NN cord-300848-0igfcixy 83 17 of of IN cord-300848-0igfcixy 83 18 the the DT cord-300848-0igfcixy 83 19 clinical clinical JJ cord-300848-0igfcixy 83 20 spectrum spectrum NN cord-300848-0igfcixy 83 21 of of IN cord-300848-0igfcixy 83 22 COVID-19 COVID-19 NNP cord-300848-0igfcixy 83 23 . . . cord-300848-0igfcixy 84 1 The the DT cord-300848-0igfcixy 84 2 authors author NNS cord-300848-0igfcixy 84 3 report report VBP cord-300848-0igfcixy 84 4 no no DT cord-300848-0igfcixy 84 5 conflict conflict NN cord-300848-0igfcixy 84 6 of of IN cord-300848-0igfcixy 84 7 interest interest NN cord-300848-0igfcixy 84 8 related relate VBN cord-300848-0igfcixy 84 9 to to IN cord-300848-0igfcixy 84 10 the the DT cord-300848-0igfcixy 84 11 content content NN cord-300848-0igfcixy 84 12 of of IN cord-300848-0igfcixy 84 13 this this DT cord-300848-0igfcixy 84 14 manuscript manuscript NN cord-300848-0igfcixy 84 15 . . . cord-300848-0igfcixy 84 16 _SP cord-300848-0igfcixy 85 1 A a DT cord-300848-0igfcixy 85 2 novel novel JJ cord-300848-0igfcixy 85 3 coronavirus coronavirus NN cord-300848-0igfcixy 85 4 from from IN cord-300848-0igfcixy 85 5 patients patient NNS cord-300848-0igfcixy 85 6 with with IN cord-300848-0igfcixy 85 7 pneumonia pneumonia NN cord-300848-0igfcixy 85 8 in in IN cord-300848-0igfcixy 85 9 China China NNP cord-300848-0igfcixy 85 10 Clinical clinical JJ cord-300848-0igfcixy 85 11 characteristics characteristic NNS cord-300848-0igfcixy 85 12 of of IN cord-300848-0igfcixy 85 13 coronavirus coronavirus NN cord-300848-0igfcixy 85 14 disease disease NN cord-300848-0igfcixy 85 15 2019 2019 CD cord-300848-0igfcixy 85 16 in in IN cord-300848-0igfcixy 85 17 China China NNP cord-300848-0igfcixy 85 18 Chronic Chronic NNP cord-300848-0igfcixy 85 19 kidney kidney NN cord-300848-0igfcixy 85 20 disease disease NN cord-300848-0igfcixy 85 21 and and CC cord-300848-0igfcixy 85 22 acute acute JJ cord-300848-0igfcixy 85 23 kidney kidney NN cord-300848-0igfcixy 85 24 injury injury NN cord-300848-0igfcixy 85 25 in in IN cord-300848-0igfcixy 85 26 the the DT cord-300848-0igfcixy 85 27 COVID-19 covid-19 JJ cord-300848-0igfcixy 85 28 Spanish spanish JJ cord-300848-0igfcixy 85 29 outbreak outbreak NN cord-300848-0igfcixy 85 30 Structural structural JJ cord-300848-0igfcixy 85 31 basis basis NN cord-300848-0igfcixy 85 32 for for IN cord-300848-0igfcixy 85 33 the the DT cord-300848-0igfcixy 85 34 recognition recognition NN cord-300848-0igfcixy 85 35 of of IN cord-300848-0igfcixy 85 36 SARS SARS NNP cord-300848-0igfcixy 85 37 - - HYPH cord-300848-0igfcixy 85 38 CoV-2 CoV-2 NNP cord-300848-0igfcixy 85 39 by by IN cord-300848-0igfcixy 85 40 full full JJ cord-300848-0igfcixy 85 41 - - HYPH cord-300848-0igfcixy 85 42 length length NN cord-300848-0igfcixy 85 43 human human JJ cord-300848-0igfcixy 85 44 ACE2 ACE2 NNP cord-300848-0igfcixy 85 45 SARS SARS NNP cord-300848-0igfcixy 85 46 - - HYPH cord-300848-0igfcixy 85 47 CoV-2 CoV-2 NNP cord-300848-0igfcixy 85 48 cell cell NN cord-300848-0igfcixy 85 49 entry entry NN cord-300848-0igfcixy 85 50 depends depend VBZ cord-300848-0igfcixy 85 51 on on IN cord-300848-0igfcixy 85 52 ACE2 ACE2 NNP cord-300848-0igfcixy 85 53 and and CC cord-300848-0igfcixy 85 54 TMPRSS2 TMPRSS2 NNP cord-300848-0igfcixy 85 55 and and CC cord-300848-0igfcixy 85 56 is be VBZ cord-300848-0igfcixy 85 57 blocked block VBN cord-300848-0igfcixy 85 58 by by IN cord-300848-0igfcixy 85 59 a a DT cord-300848-0igfcixy 85 60 clinically clinically RB cord-300848-0igfcixy 85 61 proven prove VBN cord-300848-0igfcixy 85 62 protease protease NN cord-300848-0igfcixy 85 63 inhibitor inhibitor NN cord-300848-0igfcixy 86 1 Should Should MD cord-300848-0igfcixy 87 1 COVID-19 covid-19 JJ cord-300848-0igfcixy 87 2 concern concern NN cord-300848-0igfcixy 87 3 nephrologists nephrologist NNS cord-300848-0igfcixy 87 4 ? ? . cord-300848-0igfcixy 88 1 Why why WRB cord-300848-0igfcixy 88 2 and and CC cord-300848-0igfcixy 88 3 to to TO cord-300848-0igfcixy 88 4 what what WDT cord-300848-0igfcixy 88 5 extent extent NN cord-300848-0igfcixy 88 6 ? ? . cord-300848-0igfcixy 89 1 The the DT cord-300848-0igfcixy 89 2 emerging emerge VBG cord-300848-0igfcixy 89 3 impasse impasse NN cord-300848-0igfcixy 89 4 of of IN cord-300848-0igfcixy 89 5 angiotensin angiotensin NN cord-300848-0igfcixy 89 6 blockade blockade NN cord-300848-0igfcixy 89 7 Identification Identification NNP cord-300848-0igfcixy 89 8 of of IN cord-300848-0igfcixy 89 9 a a DT cord-300848-0igfcixy 89 10 potential potential JJ cord-300848-0igfcixy 89 11 mechanism mechanism NN cord-300848-0igfcixy 89 12 of of IN cord-300848-0igfcixy 89 13 acute acute JJ cord-300848-0igfcixy 89 14 kidney kidney NN cord-300848-0igfcixy 89 15 injury injury NN cord-300848-0igfcixy 89 16 during during IN cord-300848-0igfcixy 89 17 the the DT cord-300848-0igfcixy 89 18 COVID-19 COVID-19 NNP cord-300848-0igfcixy 89 19 outbreak outbreak NN cord-300848-0igfcixy 89 20 : : : cord-300848-0igfcixy 89 21 a a DT cord-300848-0igfcixy 89 22 study study NN cord-300848-0igfcixy 89 23 based base VBN cord-300848-0igfcixy 89 24 on on IN cord-300848-0igfcixy 89 25 single single JJ cord-300848-0igfcixy 89 26 - - HYPH cord-300848-0igfcixy 89 27 cell cell NN cord-300848-0igfcixy 89 28 transcriptome transcriptome NN cord-300848-0igfcixy 89 29 analysis analysis NN cord-300848-0igfcixy 89 30 Acute acute JJ cord-300848-0igfcixy 89 31 renal renal JJ cord-300848-0igfcixy 89 32 impairment impairment NN cord-300848-0igfcixy 89 33 in in IN cord-300848-0igfcixy 89 34 coronavirusassociated coronavirusassociate VBN cord-300848-0igfcixy 89 35 severe severe JJ cord-300848-0igfcixy 89 36 acute acute JJ cord-300848-0igfcixy 89 37 respiratory respiratory JJ cord-300848-0igfcixy 89 38 syndrome syndrome NN cord-300848-0igfcixy 90 1 Renal renal JJ cord-300848-0igfcixy 90 2 histopathological histopathological JJ cord-300848-0igfcixy 90 3 analysis analysis NN cord-300848-0igfcixy 90 4 of of IN cord-300848-0igfcixy 90 5 26 26 CD cord-300848-0igfcixy 90 6 postmortem postmortem JJ cord-300848-0igfcixy 90 7 findings finding NNS cord-300848-0igfcixy 90 8 of of IN cord-300848-0igfcixy 90 9 patients patient NNS cord-300848-0igfcixy 90 10 with with IN cord-300848-0igfcixy 90 11 COVID-19 COVID-19 NNP cord-300848-0igfcixy 90 12 in in IN cord-300848-0igfcixy 90 13 China China NNP cord-300848-0igfcixy 90 14 Endothelial endothelial JJ cord-300848-0igfcixy 90 15 cell cell NN cord-300848-0igfcixy 90 16 infection infection NN cord-300848-0igfcixy 90 17 and and CC cord-300848-0igfcixy 90 18 endotheliitis endotheliitis NN cord-300848-0igfcixy 90 19 in in IN cord-300848-0igfcixy 90 20 COVID-19 COVID-19 NNP cord-300848-0igfcixy 90 21 Electron Electron NNP cord-300848-0igfcixy 90 22 microscopy microscopy NN cord-300848-0igfcixy 90 23 of of IN cord-300848-0igfcixy 90 24 SARS SARS NNP cord-300848-0igfcixy 90 25 - - HYPH cord-300848-0igfcixy 90 26 CoV-2 CoV-2 NNP cord-300848-0igfcixy 90 27 : : : cord-300848-0igfcixy 90 28 a a DT cord-300848-0igfcixy 90 29 challenging challenging JJ cord-300848-0igfcixy 90 30 task task NN cord-300848-0igfcixy 90 31 Visualization visualization NN cord-300848-0igfcixy 90 32 of of IN cord-300848-0igfcixy 90 33 putative putative JJ cord-300848-0igfcixy 90 34 coronavirus coronavirus NN cord-300848-0igfcixy 90 35 in in IN cord-300848-0igfcixy 90 36 kidney kidney NN cord-300848-0igfcixy 90 37 Multiorgan Multiorgan NNP cord-300848-0igfcixy 90 38 and and CC cord-300848-0igfcixy 90 39 renal renal JJ cord-300848-0igfcixy 90 40 tropism tropism NN cord-300848-0igfcixy 90 41 of of IN cord-300848-0igfcixy 90 42 SARS SARS NNP cord-300848-0igfcixy 90 43 - - HYPH cord-300848-0igfcixy 90 44 CoV-2 CoV-2 NNP cord-300848-0igfcixy 90 45 Identification identification NN cord-300848-0igfcixy 90 46 of of IN cord-300848-0igfcixy 90 47 Hantaan Hantaan NNP cord-300848-0igfcixy 90 48 virus virus NN cord-300848-0igfcixy 90 49 - - HYPH cord-300848-0igfcixy 90 50 related relate VBN cord-300848-0igfcixy 90 51 structures structure NNS cord-300848-0igfcixy 90 52 in in IN cord-300848-0igfcixy 90 53 kidneys kidney NNS cord-300848-0igfcixy 90 54 of of IN cord-300848-0igfcixy 90 55 cadavers cadaver NNS cord-300848-0igfcixy 90 56 with with IN cord-300848-0igfcixy 90 57 haemorrhagic haemorrhagic JJ cord-300848-0igfcixy 90 58 fever fever NN cord-300848-0igfcixy 90 59 with with IN cord-300848-0igfcixy 90 60 renal renal JJ cord-300848-0igfcixy 90 61 syndrome syndrome NN cord-300848-0igfcixy 90 62 Histopathology Histopathology NNP cord-300848-0igfcixy 90 63 of of IN cord-300848-0igfcixy 90 64 Middle Middle NNP cord-300848-0igfcixy 90 65 East East NNP cord-300848-0igfcixy 91 1 respiratory respiratory JJ cord-300848-0igfcixy 91 2 syndrome syndrome NN cord-300848-0igfcixy 91 3 coronovirus coronovirus NNP cord-300848-0igfcixy 91 4 ( ( -LRB- cord-300848-0igfcixy 91 5 MERS MERS NNP cord-300848-0igfcixy 91 6 - - HYPH cord-300848-0igfcixy 91 7 CoV CoV NNP cord-300848-0igfcixy 91 8 ) ) -RRB- cord-300848-0igfcixy 91 9 infection infection NN cord-300848-0igfcixy 91 10 -clinicopathological -clinicopathological JJ cord-300848-0igfcixy 91 11 and and CC cord-300848-0igfcixy 91 12 ultrastructural ultrastructural JJ cord-300848-0igfcixy 91 13 study study NNP cord-300848-0igfcixy 91 14 Human Human NNP cord-300848-0igfcixy 91 15 polyoma polyoma NNP cord-300848-0igfcixy 91 16 virusassociated virusassociate VBN cord-300848-0igfcixy 91 17 interstitial interstitial JJ cord-300848-0igfcixy 91 18 nephritis nephritis NN cord-300848-0igfcixy 91 19 in in IN cord-300848-0igfcixy 91 20 the the DT cord-300848-0igfcixy 91 21 allograft allograft NN cord-300848-0igfcixy 91 22 kidney kidney NN cord-300848-0igfcixy 92 1 The the DT cord-300848-0igfcixy 92 2 kidney kidney NN cord-300848-0igfcixy 92 3 as as IN cord-300848-0igfcixy 92 4 a a DT cord-300848-0igfcixy 92 5 reservoir reservoir NN cord-300848-0igfcixy 92 6 for for IN cord-300848-0igfcixy 92 7 HIV-1 HIV-1 NNP cord-300848-0igfcixy 92 8 after after IN cord-300848-0igfcixy 92 9 renal renal JJ cord-300848-0igfcixy 92 10 transplantation transplantation NN cord-300848-0igfcixy 93 1 Clinical clinical JJ cord-300848-0igfcixy 93 2 course course NN cord-300848-0igfcixy 93 3 and and CC cord-300848-0igfcixy 93 4 outcomes outcome NNS cord-300848-0igfcixy 93 5 of of IN cord-300848-0igfcixy 93 6 critically critically RB cord-300848-0igfcixy 93 7 ill ill JJ cord-300848-0igfcixy 93 8 patients patient NNS cord-300848-0igfcixy 93 9 with with IN cord-300848-0igfcixy 93 10 SARS SARS NNP cord-300848-0igfcixy 93 11 - - HYPH cord-300848-0igfcixy 93 12 CoV-2 CoV-2 NNP cord-300848-0igfcixy 93 13 pneumonia pneumonia NN cord-300848-0igfcixy 93 14 in in IN cord-300848-0igfcixy 93 15 Wuhan Wuhan NNP cord-300848-0igfcixy 93 16 , , , cord-300848-0igfcixy 93 17 China China NNP cord-300848-0igfcixy 93 18 : : : cord-300848-0igfcixy 93 19 a a DT cord-300848-0igfcixy 93 20 single single RB cord-300848-0igfcixy 93 21 - - HYPH cord-300848-0igfcixy 93 22 centered centered JJ cord-300848-0igfcixy 93 23 , , , cord-300848-0igfcixy 93 24 retrospective retrospective JJ cord-300848-0igfcixy 93 25 , , , cord-300848-0igfcixy 93 26 observational observational JJ cord-300848-0igfcixy 93 27 study study NN cord-300848-0igfcixy 93 28 Nowcasting Nowcasting NNP cord-300848-0igfcixy 93 29 and and CC cord-300848-0igfcixy 93 30 forecasting forecast VBG cord-300848-0igfcixy 93 31 the the DT cord-300848-0igfcixy 93 32 potential potential JJ cord-300848-0igfcixy 93 33 domestic domestic JJ cord-300848-0igfcixy 93 34 and and CC cord-300848-0igfcixy 93 35 international international JJ cord-300848-0igfcixy 93 36 spread spread NN cord-300848-0igfcixy 93 37 of of IN cord-300848-0igfcixy 93 38 the the DT cord-300848-0igfcixy 93 39 2019-nCoV 2019-ncov CD cord-300848-0igfcixy 93 40 outbreak outbreak NN cord-300848-0igfcixy 93 41 originating originate VBG cord-300848-0igfcixy 93 42 in in IN cord-300848-0igfcixy 93 43 Wuhan Wuhan NNP cord-300848-0igfcixy 93 44 , , , cord-300848-0igfcixy 93 45 China China NNP cord-300848-0igfcixy 93 46 : : : cord-300848-0igfcixy 94 1 a a DT cord-300848-0igfcixy 94 2 modelling modelling NN cord-300848-0igfcixy 94 3 study study NN cord-300848-0igfcixy 94 4 Renal renal JJ cord-300848-0igfcixy 94 5 involvement involvement NN cord-300848-0igfcixy 94 6 and and CC cord-300848-0igfcixy 94 7 early early JJ cord-300848-0igfcixy 94 8 prognosis prognosis NN cord-300848-0igfcixy 94 9 in in IN cord-300848-0igfcixy 94 10 patients patient NNS cord-300848-0igfcixy 94 11 with with IN cord-300848-0igfcixy 94 12 COVID-19 COVID-19 NNP cord-300848-0igfcixy 94 13 Pneumonia Pneumonia NNP cord-300848-0igfcixy 94 14 Kidney Kidney NNP cord-300848-0igfcixy 94 15 disease disease NN cord-300848-0igfcixy 94 16 is be VBZ cord-300848-0igfcixy 94 17 associated associate VBN cord-300848-0igfcixy 94 18 with with IN cord-300848-0igfcixy 94 19 in in IN cord-300848-0igfcixy 94 20 - - HYPH cord-300848-0igfcixy 94 21 hospital hospital NN cord-300848-0igfcixy 94 22 death death NN cord-300848-0igfcixy 94 23 of of IN cord-300848-0igfcixy 94 24 patients patient NNS cord-300848-0igfcixy 94 25 with with IN cord-300848-0igfcixy 94 26 COVID-19 COVID-19 NNP cord-300848-0igfcixy 94 27 Acute acute JJ cord-300848-0igfcixy 94 28 kidney kidney NN cord-300848-0igfcixy 94 29 injury injury NN cord-300848-0igfcixy 94 30 in in IN cord-300848-0igfcixy 94 31 patients patient NNS cord-300848-0igfcixy 94 32 hospitalized hospitalize VBN cord-300848-0igfcixy 94 33 with with IN cord-300848-0igfcixy 94 34 COVID-19 COVID-19 NNP