id	sid	tid	token	lemma	pos
cord-293701-u4ntxo0y	1	1	key	key	NN
cord-293701-u4ntxo0y	1	2	:	:	:
cord-293701-u4ntxo0y	2	1	cord-293701-u4ntxo0y	cord-293701-u4ntxo0y	JJ
cord-293701-u4ntxo0y	2	2	authors	author	NNS
cord-293701-u4ntxo0y	2	3	:	:	:
cord-293701-u4ntxo0y	2	4	Su	Su	NNP
cord-293701-u4ntxo0y	2	5	,	,	,
cord-293701-u4ntxo0y	2	6	Shan	Shan	NNP
cord-293701-u4ntxo0y	2	7	;	;	:
cord-293701-u4ntxo0y	2	8	Du	Du	NNP
cord-293701-u4ntxo0y	2	9	,	,	,
cord-293701-u4ntxo0y	2	10	Lanying	Lanying	NNP
cord-293701-u4ntxo0y	2	11	;	;	:
cord-293701-u4ntxo0y	2	12	Jiang	Jiang	NNP
cord-293701-u4ntxo0y	2	13	,	,	,
cord-293701-u4ntxo0y	2	14	Shibo	Shibo	NNP
cord-293701-u4ntxo0y	2	15	title	title	NN
cord-293701-u4ntxo0y	2	16	:	:	:
cord-293701-u4ntxo0y	3	1	Learning	learn	VBG
cord-293701-u4ntxo0y	3	2	from	from	IN
cord-293701-u4ntxo0y	3	3	the	the	DT
cord-293701-u4ntxo0y	3	4	past	past	NN
cord-293701-u4ntxo0y	3	5	:	:	:
cord-293701-u4ntxo0y	3	6	development	development	NN
cord-293701-u4ntxo0y	3	7	of	of	IN
cord-293701-u4ntxo0y	3	8	safe	safe	JJ
cord-293701-u4ntxo0y	3	9	and	and	CC
cord-293701-u4ntxo0y	3	10	effective	effective	JJ
cord-293701-u4ntxo0y	3	11	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	3	12	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	3	13	date	date	NN
cord-293701-u4ntxo0y	3	14	:	:	:
cord-293701-u4ntxo0y	3	15	2020	2020	CD
cord-293701-u4ntxo0y	3	16	-	-	SYM
cord-293701-u4ntxo0y	3	17	10	10	CD
cord-293701-u4ntxo0y	3	18	-	-	SYM
cord-293701-u4ntxo0y	3	19	16	16	CD
cord-293701-u4ntxo0y	3	20	journal	journal	NN
cord-293701-u4ntxo0y	3	21	:	:	:
cord-293701-u4ntxo0y	4	1	Nat	Nat	NNP
cord-293701-u4ntxo0y	4	2	Rev	Rev	NNP
cord-293701-u4ntxo0y	4	3	Microbiol	Microbiol	NNP
cord-293701-u4ntxo0y	4	4	DOI	DOI	NNP
cord-293701-u4ntxo0y	4	5	:	:	:
cord-293701-u4ntxo0y	5	1	10.1038	10.1038	CD
cord-293701-u4ntxo0y	5	2	/	/	SYM
cord-293701-u4ntxo0y	5	3	s41579	s41579	NNP
cord-293701-u4ntxo0y	5	4	-	-	HYPH
cord-293701-u4ntxo0y	5	5	020	020	CD
cord-293701-u4ntxo0y	5	6	-	-	HYPH
cord-293701-u4ntxo0y	5	7	00462-y	00462-y	NNS
cord-293701-u4ntxo0y	5	8	sha	sha	NNP
cord-293701-u4ntxo0y	5	9	:	:	:
cord-293701-u4ntxo0y	5	10	77b857067dafa3d813170004d2be714bdc8ef438	77b857067dafa3d813170004d2be714bdc8ef438	CD
cord-293701-u4ntxo0y	5	11	doc_id	doc_id	CD
cord-293701-u4ntxo0y	5	12	:	:	:
cord-293701-u4ntxo0y	5	13	293701	293701	CD
cord-293701-u4ntxo0y	5	14	cord_uid	cord_uid	NNS
cord-293701-u4ntxo0y	5	15	:	:	:
cord-293701-u4ntxo0y	6	1	u4ntxo0y	u4ntxo0y	``
cord-293701-u4ntxo0y	6	2	The	the	DT
cord-293701-u4ntxo0y	6	3	rapid	rapid	JJ
cord-293701-u4ntxo0y	6	4	spread	spread	NN
cord-293701-u4ntxo0y	6	5	of	of	IN
cord-293701-u4ntxo0y	6	6	severe	severe	JJ
cord-293701-u4ntxo0y	6	7	acute	acute	JJ
cord-293701-u4ntxo0y	6	8	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	6	9	syndrome	syndrome	NN
cord-293701-u4ntxo0y	6	10	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	6	11	2	2	CD
cord-293701-u4ntxo0y	7	1	(	(	-LRB-
cord-293701-u4ntxo0y	7	2	SARS	SARS	NNP
cord-293701-u4ntxo0y	7	3	-	-	HYPH
cord-293701-u4ntxo0y	7	4	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	7	5	)	)	-RRB-
cord-293701-u4ntxo0y	7	6	has	have	VBZ
cord-293701-u4ntxo0y	7	7	elicited	elicit	VBN
cord-293701-u4ntxo0y	7	8	an	an	DT
cord-293701-u4ntxo0y	7	9	equally	equally	RB
cord-293701-u4ntxo0y	7	10	rapid	rapid	JJ
cord-293701-u4ntxo0y	7	11	response	response	NN
cord-293701-u4ntxo0y	7	12	aiming	aim	VBG
cord-293701-u4ntxo0y	7	13	to	to	TO
cord-293701-u4ntxo0y	7	14	develop	develop	VB
cord-293701-u4ntxo0y	7	15	a	a	DT
cord-293701-u4ntxo0y	7	16	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	7	17	vaccine	vaccine	NN
cord-293701-u4ntxo0y	7	18	.	.	.
cord-293701-u4ntxo0y	8	1	These	these	DT
cord-293701-u4ntxo0y	8	2	efforts	effort	NNS
cord-293701-u4ntxo0y	8	3	are	be	VBP
cord-293701-u4ntxo0y	8	4	encouraging	encouraging	JJ
cord-293701-u4ntxo0y	8	5	;	;	:
cord-293701-u4ntxo0y	8	6	however	however	RB
cord-293701-u4ntxo0y	8	7	,	,	,
cord-293701-u4ntxo0y	8	8	comprehensive	comprehensive	JJ
cord-293701-u4ntxo0y	8	9	efficacy	efficacy	NN
cord-293701-u4ntxo0y	8	10	and	and	CC
cord-293701-u4ntxo0y	8	11	safety	safety	NN
cord-293701-u4ntxo0y	8	12	evaluations	evaluation	NNS
cord-293701-u4ntxo0y	8	13	are	be	VBP
cord-293701-u4ntxo0y	8	14	essential	essential	JJ
cord-293701-u4ntxo0y	8	15	in	in	IN
cord-293701-u4ntxo0y	8	16	the	the	DT
cord-293701-u4ntxo0y	8	17	development	development	NN
cord-293701-u4ntxo0y	8	18	of	of	IN
cord-293701-u4ntxo0y	8	19	a	a	DT
cord-293701-u4ntxo0y	8	20	vaccine	vaccine	NN
cord-293701-u4ntxo0y	8	21	,	,	,
cord-293701-u4ntxo0y	8	22	and	and	CC
cord-293701-u4ntxo0y	8	23	we	-PRON-	PRP
cord-293701-u4ntxo0y	8	24	can	can	MD
cord-293701-u4ntxo0y	8	25	learn	learn	VB
cord-293701-u4ntxo0y	8	26	from	from	IN
cord-293701-u4ntxo0y	8	27	previous	previous	JJ
cord-293701-u4ntxo0y	8	28	vaccine	vaccine	NN
cord-293701-u4ntxo0y	8	29	development	development	NN
cord-293701-u4ntxo0y	8	30	campaigns	campaign	NNS
cord-293701-u4ntxo0y	8	31	.	.	.
cord-293701-u4ntxo0y	9	1	In	in	IN
cord-293701-u4ntxo0y	9	2	this	this	DT
cord-293701-u4ntxo0y	9	3	Perspective	perspective	NN
cord-293701-u4ntxo0y	9	4	,	,	,
cord-293701-u4ntxo0y	9	5	we	-PRON-	PRP
cord-293701-u4ntxo0y	9	6	summarize	summarize	VBP
cord-293701-u4ntxo0y	9	7	examples	example	NNS
cord-293701-u4ntxo0y	9	8	of	of	IN
cord-293701-u4ntxo0y	9	9	vaccine	vaccine	NN
cord-293701-u4ntxo0y	9	10	-	-	HYPH
cord-293701-u4ntxo0y	9	11	associated	associate	VBN
cord-293701-u4ntxo0y	9	12	disease	disease	NN
cord-293701-u4ntxo0y	9	13	enhancement	enhancement	NN
cord-293701-u4ntxo0y	9	14	in	in	IN
cord-293701-u4ntxo0y	9	15	the	the	DT
cord-293701-u4ntxo0y	9	16	history	history	NN
cord-293701-u4ntxo0y	9	17	of	of	IN
cord-293701-u4ntxo0y	9	18	developing	develop	VBG
cord-293701-u4ntxo0y	9	19	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	9	20	against	against	IN
cord-293701-u4ntxo0y	9	21	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	9	22	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	9	23	virus	virus	NN
cord-293701-u4ntxo0y	9	24	,	,	,
cord-293701-u4ntxo0y	9	25	dengue	dengue	NN
cord-293701-u4ntxo0y	9	26	virus	virus	NN
cord-293701-u4ntxo0y	9	27	,	,	,
cord-293701-u4ntxo0y	9	28	SARS	SARS	NNP
cord-293701-u4ntxo0y	9	29	-	-	HYPH
cord-293701-u4ntxo0y	9	30	CoV	CoV	NNP
cord-293701-u4ntxo0y	9	31	and	and	CC
cord-293701-u4ntxo0y	9	32	Middle	Middle	NNP
cord-293701-u4ntxo0y	9	33	East	East	NNP
cord-293701-u4ntxo0y	9	34	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	9	35	syndrome	syndrome	NN
cord-293701-u4ntxo0y	9	36	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	9	37	,	,	,
cord-293701-u4ntxo0y	9	38	which	which	WDT
cord-293701-u4ntxo0y	9	39	highlight	highlight	VBP
cord-293701-u4ntxo0y	9	40	the	the	DT
cord-293701-u4ntxo0y	9	41	importance	importance	NN
cord-293701-u4ntxo0y	9	42	of	of	IN
cord-293701-u4ntxo0y	9	43	a	a	DT
cord-293701-u4ntxo0y	9	44	robust	robust	JJ
cord-293701-u4ntxo0y	9	45	safety	safety	NN
cord-293701-u4ntxo0y	9	46	and	and	CC
cord-293701-u4ntxo0y	9	47	efficacy	efficacy	NN
cord-293701-u4ntxo0y	9	48	profile	profile	NN
cord-293701-u4ntxo0y	9	49	,	,	,
cord-293701-u4ntxo0y	9	50	and	and	CC
cord-293701-u4ntxo0y	9	51	present	present	JJ
cord-293701-u4ntxo0y	9	52	recommendations	recommendation	NNS
cord-293701-u4ntxo0y	9	53	for	for	IN
cord-293701-u4ntxo0y	9	54	preclinical	preclinical	JJ
cord-293701-u4ntxo0y	9	55	and	and	CC
cord-293701-u4ntxo0y	9	56	clinical	clinical	JJ
cord-293701-u4ntxo0y	9	57	evaluation	evaluation	NN
cord-293701-u4ntxo0y	9	58	of	of	IN
cord-293701-u4ntxo0y	9	59	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	9	60	vaccine	vaccine	NN
cord-293701-u4ntxo0y	9	61	candidates	candidate	NNS
cord-293701-u4ntxo0y	9	62	as	as	RB
cord-293701-u4ntxo0y	9	63	well	well	RB
cord-293701-u4ntxo0y	9	64	as	as	IN
cord-293701-u4ntxo0y	9	65	for	for	IN
cord-293701-u4ntxo0y	9	66	vaccine	vaccine	NN
cord-293701-u4ntxo0y	9	67	design	design	NN
cord-293701-u4ntxo0y	9	68	and	and	CC
cord-293701-u4ntxo0y	9	69	optimization	optimization	NN
cord-293701-u4ntxo0y	9	70	.	.	.
cord-293701-u4ntxo0y	10	1	Since	since	IN
cord-293701-u4ntxo0y	10	2	December	December	NNP
cord-293701-u4ntxo0y	10	3	2019	2019	CD
cord-293701-u4ntxo0y	10	4	,	,	,
cord-293701-u4ntxo0y	10	5	severe	severe	JJ
cord-293701-u4ntxo0y	10	6	acute	acute	JJ
cord-293701-u4ntxo0y	10	7	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	10	8	syndrome	syndrome	NN
cord-293701-u4ntxo0y	10	9	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	10	10	2	2	CD
cord-293701-u4ntxo0y	10	11	(	(	-LRB-
cord-293701-u4ntxo0y	10	12	SARS	SARS	NNP
cord-293701-u4ntxo0y	10	13	-	-	HYPH
cord-293701-u4ntxo0y	10	14	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	10	15	)	)	-RRB-
cord-293701-u4ntxo0y	10	16	has	have	VBZ
cord-293701-u4ntxo0y	10	17	rapidly	rapidly	RB
cord-293701-u4ntxo0y	10	18	spread	spread	VBN
cord-293701-u4ntxo0y	10	19	around	around	IN
cord-293701-u4ntxo0y	10	20	the	the	DT
cord-293701-u4ntxo0y	10	21	globe	globe	NN
cord-293701-u4ntxo0y	10	22	.	.	.
cord-293701-u4ntxo0y	11	1	The	the	DT
cord-293701-u4ntxo0y	11	2	intensity	intensity	NN
cord-293701-u4ntxo0y	11	3	and	and	CC
cord-293701-u4ntxo0y	11	4	rapidity	rapidity	NN
cord-293701-u4ntxo0y	11	5	of	of	IN
cord-293701-u4ntxo0y	11	6	SARS	SARS	NNP
cord-293701-u4ntxo0y	11	7	-	-	HYPH
cord-293701-u4ntxo0y	11	8	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	11	9	transmission	transmission	NN
cord-293701-u4ntxo0y	11	10	have	have	VBP
cord-293701-u4ntxo0y	11	11	led	lead	VBN
cord-293701-u4ntxo0y	11	12	to	to	IN
cord-293701-u4ntxo0y	11	13	substantial	substantial	JJ
cord-293701-u4ntxo0y	11	14	morbidity	morbidity	NN
cord-293701-u4ntxo0y	11	15	and	and	CC
cord-293701-u4ntxo0y	11	16	mortality	mortality	NN
cord-293701-u4ntxo0y	11	17	and	and	CC
cord-293701-u4ntxo0y	11	18	put	put	VBD
cord-293701-u4ntxo0y	11	19	considerable	considerable	JJ
cord-293701-u4ntxo0y	11	20	pressure	pressure	NN
cord-293701-u4ntxo0y	11	21	on	on	IN
cord-293701-u4ntxo0y	11	22	public	public	JJ
cord-293701-u4ntxo0y	11	23	health	health	NN
cord-293701-u4ntxo0y	11	24	systems	system	NNS
cord-293701-u4ntxo0y	11	25	around	around	IN
cord-293701-u4ntxo0y	11	26	the	the	DT
cord-293701-u4ntxo0y	11	27	world	world	NN
cord-293701-u4ntxo0y	11	28	and	and	CC
cord-293701-u4ntxo0y	11	29	the	the	DT
cord-293701-u4ntxo0y	11	30	global	global	JJ
cord-293701-u4ntxo0y	11	31	economy	economy	NN
cord-293701-u4ntxo0y	11	32	.	.	.
cord-293701-u4ntxo0y	12	1	Consequently	consequently	RB
cord-293701-u4ntxo0y	12	2	,	,	,
cord-293701-u4ntxo0y	12	3	developing	develop	VBG
cord-293701-u4ntxo0y	12	4	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	12	5	and	and	CC
cord-293701-u4ntxo0y	12	6	therapeutics	therapeutic	NNS
cord-293701-u4ntxo0y	12	7	against	against	IN
cord-293701-u4ntxo0y	12	8	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	12	9	is	be	VBZ
cord-293701-u4ntxo0y	12	10	of	of	IN
cord-293701-u4ntxo0y	12	11	highest	high	JJS
cord-293701-u4ntxo0y	12	12	priority	priority	NN
cord-293701-u4ntxo0y	12	13	and	and	CC
cord-293701-u4ntxo0y	12	14	a	a	DT
cord-293701-u4ntxo0y	12	15	very	very	RB
cord-293701-u4ntxo0y	12	16	active	active	JJ
cord-293701-u4ntxo0y	12	17	field	field	NN
cord-293701-u4ntxo0y	12	18	1	1	CD
cord-293701-u4ntxo0y	12	19	.	.	.
cord-293701-u4ntxo0y	13	1	Vaccines	vaccine	NNS
cord-293701-u4ntxo0y	13	2	can	can	MD
cord-293701-u4ntxo0y	13	3	prevent	prevent	VB
cord-293701-u4ntxo0y	13	4	disease	disease	NN
cord-293701-u4ntxo0y	13	5	in	in	IN
cord-293701-u4ntxo0y	13	6	large	large	JJ
cord-293701-u4ntxo0y	13	7	populations	population	NNS
cord-293701-u4ntxo0y	13	8	at	at	IN
cord-293701-u4ntxo0y	13	9	relatively	relatively	RB
cord-293701-u4ntxo0y	13	10	low	low	JJ
cord-293701-u4ntxo0y	13	11	cost	cost	NN
cord-293701-u4ntxo0y	13	12	,	,	,
cord-293701-u4ntxo0y	13	13	thus	thus	RB
cord-293701-u4ntxo0y	13	14	being	be	VBG
cord-293701-u4ntxo0y	13	15	a	a	DT
cord-293701-u4ntxo0y	13	16	powerful	powerful	JJ
cord-293701-u4ntxo0y	13	17	tool	tool	NN
cord-293701-u4ntxo0y	13	18	to	to	TO
cord-293701-u4ntxo0y	13	19	mitigate	mitigate	VB
cord-293701-u4ntxo0y	13	20	the	the	DT
cord-293701-u4ntxo0y	13	21	impacts	impact	NNS
cord-293701-u4ntxo0y	13	22	of	of	IN
cord-293701-u4ntxo0y	13	23	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	13	24	.	.	.
cord-293701-u4ntxo0y	14	1	On	on	IN
cord-293701-u4ntxo0y	14	2	16	16	CD
cord-293701-u4ntxo0y	14	3	March	March	NNP
cord-293701-u4ntxo0y	14	4	2020	2020	CD
cord-293701-u4ntxo0y	14	5	,	,	,
cord-293701-u4ntxo0y	14	6	the	the	DT
cord-293701-u4ntxo0y	14	7	mRNA	mRNA	NNP
cord-293701-u4ntxo0y	14	8	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	14	9	vaccine	vaccine	NN
cord-293701-u4ntxo0y	14	10	(	(	-LRB-
cord-293701-u4ntxo0y	14	11	mRNA-1273	mRNA-1273	NNP
cord-293701-u4ntxo0y	14	12	)	)	-RRB-
cord-293701-u4ntxo0y	14	13	from	from	IN
cord-293701-u4ntxo0y	14	14	Moderna	Moderna	NNP
cord-293701-u4ntxo0y	14	15	and	and	CC
cord-293701-u4ntxo0y	14	16	the	the	DT
cord-293701-u4ntxo0y	14	17	non	non	JJ
cord-293701-u4ntxo0y	14	18	-	-	JJ
cord-293701-u4ntxo0y	14	19	replicating	replicating	JJ
cord-293701-u4ntxo0y	14	20	adenovirus	adenovirus	NN
cord-293701-u4ntxo0y	14	21	type	type	NN
cord-293701-u4ntxo0y	14	22	5	5	CD
cord-293701-u4ntxo0y	14	23	(	(	-LRB-
cord-293701-u4ntxo0y	14	24	Ad5)-vectored	ad5)-vectored	JJ
cord-293701-u4ntxo0y	14	25	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	14	26	vaccine	vaccine	NN
cord-293701-u4ntxo0y	14	27	(	(	-LRB-
cord-293701-u4ntxo0y	14	28	Ad5-nCoV	Ad5-nCoV	NNP
cord-293701-u4ntxo0y	14	29	)	)	-RRB-
cord-293701-u4ntxo0y	14	30	from	from	IN
cord-293701-u4ntxo0y	14	31	CanSino	CanSino	NNP
cord-293701-u4ntxo0y	14	32	entered	enter	VBD
cord-293701-u4ntxo0y	14	33	phase	phase	NN
cord-293701-u4ntxo0y	15	1	I	-PRON-	PRP
cord-293701-u4ntxo0y	15	2	clinical	clinical	JJ
cord-293701-u4ntxo0y	15	3	trials	trial	NNS
cord-293701-u4ntxo0y	15	4	2	2	CD
cord-293701-u4ntxo0y	15	5	,	,	,
cord-293701-u4ntxo0y	15	6	3	3	CD
cord-293701-u4ntxo0y	15	7	.	.	.
cord-293701-u4ntxo0y	16	1	In	in	IN
cord-293701-u4ntxo0y	16	2	April	April	NNP
cord-293701-u4ntxo0y	16	3	2020	2020	CD
cord-293701-u4ntxo0y	16	4	,	,	,
cord-293701-u4ntxo0y	16	5	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	16	6	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	16	7	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	16	8	manufactured	manufacture	VBN
cord-293701-u4ntxo0y	16	9	by	by	IN
cord-293701-u4ntxo0y	16	10	Sinovac	Sinovac	NNP
cord-293701-u4ntxo0y	16	11	(	(	-LRB-
cord-293701-u4ntxo0y	16	12	PiCoVacc	PiCoVacc	NNP
cord-293701-u4ntxo0y	16	13	)	)	-RRB-
cord-293701-u4ntxo0y	16	14	,	,	,
cord-293701-u4ntxo0y	16	15	the	the	DT
cord-293701-u4ntxo0y	16	16	Beijing	Beijing	NNP
cord-293701-u4ntxo0y	16	17	Institute	Institute	NNP
cord-293701-u4ntxo0y	16	18	of	of	IN
cord-293701-u4ntxo0y	16	19	Biological	Biological	NNP
cord-293701-u4ntxo0y	16	20	Products	Products	NNP
cord-293701-u4ntxo0y	16	21	(	(	-LRB-
cord-293701-u4ntxo0y	16	22	BBIBP	BBIBP	NNP
cord-293701-u4ntxo0y	16	23	-	-	HYPH
cord-293701-u4ntxo0y	16	24	CorV	CorV	NNP
cord-293701-u4ntxo0y	16	25	)	)	-RRB-
cord-293701-u4ntxo0y	16	26	and	and	CC
cord-293701-u4ntxo0y	16	27	the	the	DT
cord-293701-u4ntxo0y	16	28	Wuhan	Wuhan	NNP
cord-293701-u4ntxo0y	16	29	Institute	Institute	NNP
cord-293701-u4ntxo0y	16	30	of	of	IN
cord-293701-u4ntxo0y	16	31	Biological	Biological	NNP
cord-293701-u4ntxo0y	16	32	Products	Products	NNPS
cord-293701-u4ntxo0y	17	1	(	(	-LRB-
cord-293701-u4ntxo0y	17	2	Sinopharm	Sinopharm	NNP
cord-293701-u4ntxo0y	17	3	-	-	HYPH
cord-293701-u4ntxo0y	17	4	Wuhan	Wuhan	NNP
cord-293701-u4ntxo0y	17	5	inactivated	inactivate	VBD
cord-293701-u4ntxo0y	17	6	vaccine	vaccine	NN
cord-293701-u4ntxo0y	17	7	)	)	-RRB-
cord-293701-u4ntxo0y	17	8	,	,	,
cord-293701-u4ntxo0y	17	9	as	as	RB
cord-293701-u4ntxo0y	17	10	well	well	RB
cord-293701-u4ntxo0y	17	11	as	as	IN
cord-293701-u4ntxo0y	17	12	Inovio	Inovio	NNP
cord-293701-u4ntxo0y	17	13	's	's	POS
cord-293701-u4ntxo0y	17	14	DNA	dna	NN
cord-293701-u4ntxo0y	17	15	vaccine	vaccine	NN
cord-293701-u4ntxo0y	17	16	(	(	-LRB-
cord-293701-u4ntxo0y	17	17	INO-4800	INO-4800	NNP
cord-293701-u4ntxo0y	17	18	)	)	-RRB-
cord-293701-u4ntxo0y	17	19	,	,	,
cord-293701-u4ntxo0y	17	20	entered	enter	VBD
cord-293701-u4ntxo0y	17	21	phase	phase	NN
cord-293701-u4ntxo0y	18	1	I	-PRON-	PRP
cord-293701-u4ntxo0y	18	2	clinical	clinical	JJ
cord-293701-u4ntxo0y	18	3	trials	trial	NNS
cord-293701-u4ntxo0y	18	4	4	4	CD
cord-293701-u4ntxo0y	18	5	.	.	.
cord-293701-u4ntxo0y	19	1	One	one	CD
cord-293701-u4ntxo0y	19	2	month	month	NN
cord-293701-u4ntxo0y	19	3	later	later	RB
cord-293701-u4ntxo0y	19	4	,	,	,
cord-293701-u4ntxo0y	19	5	five	five	CD
cord-293701-u4ntxo0y	19	6	more	more	JJR
cord-293701-u4ntxo0y	19	7	candidates	candidate	NNS
cord-293701-u4ntxo0y	19	8	had	have	VBD
cord-293701-u4ntxo0y	19	9	also	also	RB
cord-293701-u4ntxo0y	19	10	entered	enter	VBN
cord-293701-u4ntxo0y	19	11	phase	phase	NN
cord-293701-u4ntxo0y	19	12	I	-PRON-	PRP
cord-293701-u4ntxo0y	19	13	clinical	clinical	JJ
cord-293701-u4ntxo0y	19	14	trials	trial	NNS
cord-293701-u4ntxo0y	19	15	,	,	,
cord-293701-u4ntxo0y	19	16	and	and	CC
cord-293701-u4ntxo0y	19	17	more	more	JJR
cord-293701-u4ntxo0y	19	18	than	than	IN
cord-293701-u4ntxo0y	19	19	100	100	CD
cord-293701-u4ntxo0y	19	20	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	19	21	vaccine	vaccine	NN
cord-293701-u4ntxo0y	19	22	candidates	candidate	NNS
cord-293701-u4ntxo0y	19	23	were	be	VBD
cord-293701-u4ntxo0y	19	24	in	in	IN
cord-293701-u4ntxo0y	19	25	results	result	NNS
cord-293701-u4ntxo0y	19	26	,	,	,
cord-293701-u4ntxo0y	19	27	all	all	DT
cord-293701-u4ntxo0y	19	28	of	of	IN
cord-293701-u4ntxo0y	19	29	these	these	DT
cord-293701-u4ntxo0y	19	30	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	19	31	induced	induce	VBN
cord-293701-u4ntxo0y	19	32	antibodies	antibody	NNS
cord-293701-u4ntxo0y	19	33	against	against	IN
cord-293701-u4ntxo0y	19	34	the	the	DT
cord-293701-u4ntxo0y	19	35	spike	spike	NN
cord-293701-u4ntxo0y	19	36	protein	protein	NN
cord-293701-u4ntxo0y	19	37	(	(	-LRB-
cord-293701-u4ntxo0y	19	38	S	s	NN
cord-293701-u4ntxo0y	19	39	protein	protein	NN
cord-293701-u4ntxo0y	19	40	)	)	-RRB-
cord-293701-u4ntxo0y	19	41	and	and	CC
cord-293701-u4ntxo0y	19	42	the	the	DT
cord-293701-u4ntxo0y	19	43	receptor	receptor	NN
cord-293701-u4ntxo0y	19	44	-	-	HYPH
cord-293701-u4ntxo0y	19	45	binding	bind	VBG
cord-293701-u4ntxo0y	19	46	domain	domain	NN
cord-293701-u4ntxo0y	19	47	(	(	-LRB-
cord-293701-u4ntxo0y	19	48	RBD	RBD	NNP
cord-293701-u4ntxo0y	19	49	)	)	-RRB-
cord-293701-u4ntxo0y	19	50	,	,	,
cord-293701-u4ntxo0y	19	51	including	include	VBG
cord-293701-u4ntxo0y	19	52	antibodies	antibody	NNS
cord-293701-u4ntxo0y	19	53	that	that	WDT
cord-293701-u4ntxo0y	19	54	neutralized	neutralize	VBD
cord-293701-u4ntxo0y	19	55	pseudotyped	pseudotyped	NNP
cord-293701-u4ntxo0y	19	56	and	and	CC
cord-293701-u4ntxo0y	19	57	live	live	JJ
cord-293701-u4ntxo0y	19	58	SARS	SARS	NNP
cord-293701-u4ntxo0y	19	59	-	-	HYPH
cord-293701-u4ntxo0y	19	60	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	19	61	.	.	.
cord-293701-u4ntxo0y	20	1	Some	some	DT
cord-293701-u4ntxo0y	20	2	reports	report	NNS
cord-293701-u4ntxo0y	20	3	have	have	VBP
cord-293701-u4ntxo0y	20	4	shown	show	VBN
cord-293701-u4ntxo0y	20	5	that	that	IN
cord-293701-u4ntxo0y	20	6	NAb	NAb	NNS
cord-293701-u4ntxo0y	20	7	titres	titre	NNS
cord-293701-u4ntxo0y	20	8	were	be	VBD
cord-293701-u4ntxo0y	20	9	strongly	strongly	RB
cord-293701-u4ntxo0y	20	10	correlated	correlate	VBN
cord-293701-u4ntxo0y	20	11	with	with	IN
cord-293701-u4ntxo0y	20	12	the	the	DT
cord-293701-u4ntxo0y	20	13	concentration	concentration	NN
cord-293701-u4ntxo0y	20	14	of	of	IN
cord-293701-u4ntxo0y	20	15	RBD	RBD	NNP
cord-293701-u4ntxo0y	20	16	-	-	HYPH
cord-293701-u4ntxo0y	20	17	binding	bind	VBG
cord-293701-u4ntxo0y	20	18	IgG	IgG	NNP
cord-293701-u4ntxo0y	20	19	15	15	CD
cord-293701-u4ntxo0y	20	20	,	,	,
cord-293701-u4ntxo0y	20	21	16	16	CD
cord-293701-u4ntxo0y	20	22	.	.	.
cord-293701-u4ntxo0y	21	1	Very	very	RB
cord-293701-u4ntxo0y	21	2	recently	recently	RB
cord-293701-u4ntxo0y	21	3	,	,	,
cord-293701-u4ntxo0y	21	4	AstraZeneca	AstraZeneca	NNP
cord-293701-u4ntxo0y	21	5	announced	announce	VBD
cord-293701-u4ntxo0y	21	6	a	a	DT
cord-293701-u4ntxo0y	21	7	pause	pause	NN
cord-293701-u4ntxo0y	21	8	in	in	IN
cord-293701-u4ntxo0y	21	9	the	the	DT
cord-293701-u4ntxo0y	21	10	phase	phase	NN
cord-293701-u4ntxo0y	21	11	III	iii	CD
cord-293701-u4ntxo0y	21	12	clinical	clinical	JJ
cord-293701-u4ntxo0y	21	13	trial	trial	NN
cord-293701-u4ntxo0y	21	14	of	of	IN
cord-293701-u4ntxo0y	21	15	its	-PRON-	PRP$
cord-293701-u4ntxo0y	21	16	ChAdOx1	ChAdOx1	NNP
cord-293701-u4ntxo0y	21	17	nCoV-19	ncov-19	CD
cord-293701-u4ntxo0y	21	18	vaccine	vaccine	NN
cord-293701-u4ntxo0y	21	19	because	because	IN
cord-293701-u4ntxo0y	21	20	of	of	IN
cord-293701-u4ntxo0y	21	21	an	an	DT
cord-293701-u4ntxo0y	21	22	unexpected	unexpected	JJ
cord-293701-u4ntxo0y	21	23	adverse	adverse	JJ
cord-293701-u4ntxo0y	21	24	reaction	reaction	NN
cord-293701-u4ntxo0y	21	25	,	,	,
cord-293701-u4ntxo0y	21	26	although	although	IN
cord-293701-u4ntxo0y	21	27	the	the	DT
cord-293701-u4ntxo0y	21	28	trial	trial	NN
cord-293701-u4ntxo0y	21	29	has	have	VBZ
cord-293701-u4ntxo0y	21	30	resumed	resume	VBN
cord-293701-u4ntxo0y	21	31	in	in	IN
cord-293701-u4ntxo0y	21	32	the	the	DT
cord-293701-u4ntxo0y	21	33	United	United	NNP
cord-293701-u4ntxo0y	21	34	Kingdom	Kingdom	NNP
cord-293701-u4ntxo0y	21	35	.	.	.
cord-293701-u4ntxo0y	22	1	Furthermore	furthermore	RB
cord-293701-u4ntxo0y	22	2	,	,	,
cord-293701-u4ntxo0y	22	3	Russia	Russia	NNP
cord-293701-u4ntxo0y	22	4	recently	recently	RB
cord-293701-u4ntxo0y	22	5	approved	approve	VBD
cord-293701-u4ntxo0y	22	6	a	a	DT
cord-293701-u4ntxo0y	22	7	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	22	8	Ad26	Ad26	NNP
cord-293701-u4ntxo0y	22	9	and	and	CC
cord-293701-u4ntxo0y	22	10	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	22	11	Ad5	ad5	CD
cord-293701-u4ntxo0y	22	12	vector	vector	NN
cord-293701-u4ntxo0y	22	13	-	-	HYPH
cord-293701-u4ntxo0y	22	14	based	base	VBN
cord-293701-u4ntxo0y	22	15	heterologous	heterologous	NNP
cord-293701-u4ntxo0y	22	16	primeboost	primeboost	NNP
cord-293701-u4ntxo0y	23	1	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	23	2	vaccine	vaccine	NN
cord-293701-u4ntxo0y	23	3	for	for	IN
cord-293701-u4ntxo0y	23	4	use	use	NN
cord-293701-u4ntxo0y	23	5	in	in	IN
cord-293701-u4ntxo0y	23	6	tens	ten	NNS
cord-293701-u4ntxo0y	23	7	of	of	IN
cord-293701-u4ntxo0y	23	8	thousands	thousand	NNS
cord-293701-u4ntxo0y	23	9	of	of	IN
cord-293701-u4ntxo0y	23	10	people	people	NNS
cord-293701-u4ntxo0y	23	11	after	after	IN
cord-293701-u4ntxo0y	23	12	conducting	conduct	VBG
cord-293701-u4ntxo0y	23	13	non	non	JJ
cord-293701-u4ntxo0y	23	14	-	-	JJ
cord-293701-u4ntxo0y	23	15	randomized	randomized	JJ
cord-293701-u4ntxo0y	23	16	phase	phase	NN
cord-293701-u4ntxo0y	23	17	I	I	NNP
cord-293701-u4ntxo0y	23	18	/	/	SYM
cord-293701-u4ntxo0y	23	19	II	II	NNP
cord-293701-u4ntxo0y	23	20	studies	study	NNS
cord-293701-u4ntxo0y	23	21	17	17	CD
cord-293701-u4ntxo0y	23	22	.	.	.
cord-293701-u4ntxo0y	24	1	Vaccine	vaccine	NN
cord-293701-u4ntxo0y	24	2	safety	safety	NN
cord-293701-u4ntxo0y	24	3	remains	remain	VBZ
cord-293701-u4ntxo0y	24	4	a	a	DT
cord-293701-u4ntxo0y	24	5	key	key	JJ
cord-293701-u4ntxo0y	24	6	question	question	NN
cord-293701-u4ntxo0y	24	7	in	in	IN
cord-293701-u4ntxo0y	24	8	phase	phase	NN
cord-293701-u4ntxo0y	24	9	III	iii	CD
cord-293701-u4ntxo0y	24	10	clinical	clinical	JJ
cord-293701-u4ntxo0y	24	11	trials	trial	NNS
cord-293701-u4ntxo0y	24	12	and	and	CC
cord-293701-u4ntxo0y	24	13	in	in	IN
cord-293701-u4ntxo0y	24	14	the	the	DT
cord-293701-u4ntxo0y	24	15	future	future	JJ
cord-293701-u4ntxo0y	24	16	application	application	NN
cord-293701-u4ntxo0y	24	17	of	of	IN
cord-293701-u4ntxo0y	24	18	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	24	19	,	,	,
cord-293701-u4ntxo0y	24	20	in	in	IN
cord-293701-u4ntxo0y	24	21	particular	particular	JJ
cord-293701-u4ntxo0y	24	22	for	for	IN
cord-293701-u4ntxo0y	24	23	vaccine	vaccine	NN
cord-293701-u4ntxo0y	24	24	-	-	HYPH
cord-293701-u4ntxo0y	24	25	related	relate	VBN
cord-293701-u4ntxo0y	24	26	immunopathologies	immunopathology	NNS
cord-293701-u4ntxo0y	24	27	occurring	occur	VBG
cord-293701-u4ntxo0y	24	28	when	when	WRB
cord-293701-u4ntxo0y	24	29	vaccinated	vaccinated	JJ
cord-293701-u4ntxo0y	24	30	people	people	NNS
cord-293701-u4ntxo0y	24	31	are	be	VBP
cord-293701-u4ntxo0y	24	32	naturally	naturally	RB
cord-293701-u4ntxo0y	24	33	infected	infect	VBN
cord-293701-u4ntxo0y	24	34	,	,	,
cord-293701-u4ntxo0y	24	35	as	as	IN
cord-293701-u4ntxo0y	24	36	described	describe	VBN
cord-293701-u4ntxo0y	24	37	below	below	RB
cord-293701-u4ntxo0y	24	38	.	.	.
cord-293701-u4ntxo0y	25	1	In	in	IN
cord-293701-u4ntxo0y	25	2	the	the	DT
cord-293701-u4ntxo0y	25	3	1960s	1960	NNS
cord-293701-u4ntxo0y	25	4	,	,	,
cord-293701-u4ntxo0y	25	5	scientists	scientist	NNS
cord-293701-u4ntxo0y	25	6	found	find	VBD
cord-293701-u4ntxo0y	25	7	that	that	IN
cord-293701-u4ntxo0y	25	8	antiviral	antiviral	JJ
cord-293701-u4ntxo0y	25	9	antisera	antisera	NN
cord-293701-u4ntxo0y	25	10	might	may	MD
cord-293701-u4ntxo0y	25	11	result	result	VB
cord-293701-u4ntxo0y	25	12	in	in	IN
cord-293701-u4ntxo0y	25	13	an	an	DT
cord-293701-u4ntxo0y	25	14	exceptional	exceptional	JJ
cord-293701-u4ntxo0y	25	15	increase	increase	NN
cord-293701-u4ntxo0y	25	16	in	in	IN
cord-293701-u4ntxo0y	25	17	viral	viral	JJ
cord-293701-u4ntxo0y	25	18	infectivity	infectivity	NN
cord-293701-u4ntxo0y	25	19	of	of	IN
cord-293701-u4ntxo0y	25	20	animal	animal	NN
cord-293701-u4ntxo0y	25	21	viruses	virus	NNS
cord-293701-u4ntxo0y	25	22	18	18	CD
cord-293701-u4ntxo0y	25	23	.	.	.
cord-293701-u4ntxo0y	26	1	This	this	DT
cord-293701-u4ntxo0y	26	2	phenomenon	phenomenon	NN
cord-293701-u4ntxo0y	26	3	that	that	IN
cord-293701-u4ntxo0y	26	4	viral	viral	JJ
cord-293701-u4ntxo0y	26	5	infection	infection	NN
cord-293701-u4ntxo0y	26	6	can	can	MD
cord-293701-u4ntxo0y	26	7	be	be	VB
cord-293701-u4ntxo0y	26	8	enhanced	enhance	VBN
cord-293701-u4ntxo0y	26	9	by	by	IN
cord-293701-u4ntxo0y	26	10	internalization	internalization	NN
cord-293701-u4ntxo0y	26	11	associated	associate	VBN
cord-293701-u4ntxo0y	26	12	with	with	IN
cord-293701-u4ntxo0y	26	13	antibody	antibody	NN
cord-293701-u4ntxo0y	26	14	Fc	Fc	NNP
cord-293701-u4ntxo0y	26	15	receptors	receptor	NNS
cord-293701-u4ntxo0y	26	16	(	(	-LRB-
cord-293701-u4ntxo0y	26	17	FcRs	FcRs	NNP
cord-293701-u4ntxo0y	26	18	)	)	-RRB-
cord-293701-u4ntxo0y	26	19	,	,	,
cord-293701-u4ntxo0y	26	20	denoted	denote	VBN
cord-293701-u4ntxo0y	26	21	as	as	IN
cord-293701-u4ntxo0y	26	22	'	'	``
cord-293701-u4ntxo0y	26	23	antibody	antibody	NN
cord-293701-u4ntxo0y	26	24	-	-	HYPH
cord-293701-u4ntxo0y	26	25	dependent	dependent	JJ
cord-293701-u4ntxo0y	26	26	enhancement	enhancement	NN
cord-293701-u4ntxo0y	26	27	'	'	''
cord-293701-u4ntxo0y	26	28	(	(	-LRB-
cord-293701-u4ntxo0y	26	29	ADE	ADE	NNP
cord-293701-u4ntxo0y	26	30	;	;	:
cord-293701-u4ntxo0y	26	31	Box	Box	NNP
cord-293701-u4ntxo0y	26	32	1	1	CD
cord-293701-u4ntxo0y	26	33	)	)	-RRB-
cord-293701-u4ntxo0y	26	34	,	,	,
cord-293701-u4ntxo0y	26	35	was	be	VBD
cord-293701-u4ntxo0y	26	36	then	then	RB
cord-293701-u4ntxo0y	26	37	widely	widely	RB
cord-293701-u4ntxo0y	26	38	reported	report	VBN
cord-293701-u4ntxo0y	26	39	in	in	IN
cord-293701-u4ntxo0y	26	40	infections	infection	NNS
cord-293701-u4ntxo0y	26	41	with	with	IN
cord-293701-u4ntxo0y	26	42	flaviviruses	flavivirus	NNS
cord-293701-u4ntxo0y	26	43	19	19	CD
cord-293701-u4ntxo0y	26	44	,	,	,
cord-293701-u4ntxo0y	26	45	20	20	CD
cord-293701-u4ntxo0y	26	46	and	and	CC
cord-293701-u4ntxo0y	26	47	other	other	JJ
cord-293701-u4ntxo0y	26	48	viruses	virus	NNS
cord-293701-u4ntxo0y	26	49	21	21	CD
cord-293701-u4ntxo0y	26	50	,	,	,
cord-293701-u4ntxo0y	26	51	22	22	CD
cord-293701-u4ntxo0y	26	52	.	.	.
cord-293701-u4ntxo0y	27	1	Later	later	RB
cord-293701-u4ntxo0y	27	2	,	,	,
cord-293701-u4ntxo0y	27	3	more	more	JJR
cord-293701-u4ntxo0y	27	4	antibody	antibody	NN
cord-293701-u4ntxo0y	27	5	FcR	fcr	NN
cord-293701-u4ntxo0y	27	6	-	-	HYPH
cord-293701-u4ntxo0y	27	7	mediated	mediate	VBN
cord-293701-u4ntxo0y	27	8	effects	effect	NNS
cord-293701-u4ntxo0y	27	9	,	,	,
cord-293701-u4ntxo0y	27	10	such	such	JJ
cord-293701-u4ntxo0y	27	11	as	as	IN
cord-293701-u4ntxo0y	27	12	complement	complement	JJ
cord-293701-u4ntxo0y	27	13	activation	activation	NN
cord-293701-u4ntxo0y	27	14	and	and	CC
cord-293701-u4ntxo0y	27	15	release	release	NN
cord-293701-u4ntxo0y	27	16	of	of	IN
cord-293701-u4ntxo0y	27	17	inflammatory	inflammatory	JJ
cord-293701-u4ntxo0y	27	18	cytokines	cytokine	NNS
cord-293701-u4ntxo0y	27	19	,	,	,
cord-293701-u4ntxo0y	27	20	were	be	VBD
cord-293701-u4ntxo0y	27	21	reported	report	VBN
cord-293701-u4ntxo0y	27	22	to	to	TO
cord-293701-u4ntxo0y	27	23	be	be	VB
cord-293701-u4ntxo0y	27	24	involved	involve	VBN
cord-293701-u4ntxo0y	27	25	in	in	IN
cord-293701-u4ntxo0y	27	26	severer	severe	JJR
cord-293701-u4ntxo0y	27	27	disease	disease	NN
cord-293701-u4ntxo0y	27	28	23	23	CD
cord-293701-u4ntxo0y	27	29	.	.	.
cord-293701-u4ntxo0y	28	1	ADE	ADE	NNP
cord-293701-u4ntxo0y	28	2	has	have	VBZ
cord-293701-u4ntxo0y	28	3	also	also	RB
cord-293701-u4ntxo0y	28	4	been	be	VBN
cord-293701-u4ntxo0y	28	5	observed	observe	VBN
cord-293701-u4ntxo0y	28	6	in	in	IN
cord-293701-u4ntxo0y	28	7	vaccinated	vaccinated	JJ
cord-293701-u4ntxo0y	28	8	animals	animal	NNS
cord-293701-u4ntxo0y	28	9	after	after	IN
cord-293701-u4ntxo0y	28	10	viral	viral	JJ
cord-293701-u4ntxo0y	28	11	challenge	challenge	NN
cord-293701-u4ntxo0y	28	12	with	with	IN
cord-293701-u4ntxo0y	28	13	the	the	DT
cord-293701-u4ntxo0y	28	14	corresponding	corresponding	JJ
cord-293701-u4ntxo0y	28	15	virus	virus	NN
cord-293701-u4ntxo0y	28	16	24	24	CD
cord-293701-u4ntxo0y	28	17	.	.	.
cord-293701-u4ntxo0y	29	1	For	for	IN
cord-293701-u4ntxo0y	29	2	example	example	NN
cord-293701-u4ntxo0y	29	3	,	,	,
cord-293701-u4ntxo0y	29	4	cats	cat	NNS
cord-293701-u4ntxo0y	29	5	immunized	immunize	VBN
cord-293701-u4ntxo0y	29	6	with	with	IN
cord-293701-u4ntxo0y	29	7	a	a	DT
cord-293701-u4ntxo0y	29	8	vaccine	vaccine	NN
cord-293701-u4ntxo0y	29	9	expressing	express	VBG
cord-293701-u4ntxo0y	29	10	the	the	DT
cord-293701-u4ntxo0y	29	11	feline	feline	JJ
cord-293701-u4ntxo0y	29	12	infectious	infectious	JJ
cord-293701-u4ntxo0y	29	13	peritonitis	peritonitis	NN
cord-293701-u4ntxo0y	29	14	virus	virus	NN
cord-293701-u4ntxo0y	29	15	(	(	-LRB-
cord-293701-u4ntxo0y	29	16	FIPV	FIPV	NNP
cord-293701-u4ntxo0y	29	17	)	)	-RRB-
cord-293701-u4ntxo0y	29	18	S	s	NN
cord-293701-u4ntxo0y	29	19	protein	protein	NN
cord-293701-u4ntxo0y	29	20	on	on	IN
cord-293701-u4ntxo0y	29	21	a	a	DT
cord-293701-u4ntxo0y	29	22	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	29	23	pox	pox	NN
cord-293701-u4ntxo0y	29	24	virus	virus	NN
cord-293701-u4ntxo0y	29	25	vector	vector	NN
cord-293701-u4ntxo0y	29	26	died	die	VBD
cord-293701-u4ntxo0y	29	27	earlier	early	RBR
cord-293701-u4ntxo0y	29	28	than	than	IN
cord-293701-u4ntxo0y	29	29	control	control	NN
cord-293701-u4ntxo0y	29	30	animals	animal	NNS
cord-293701-u4ntxo0y	29	31	when	when	WRB
cord-293701-u4ntxo0y	29	32	challenged	challenge	VBN
cord-293701-u4ntxo0y	29	33	with	with	IN
cord-293701-u4ntxo0y	29	34	FIPV	FIPV	NNP
cord-293701-u4ntxo0y	29	35	25	25	CD
cord-293701-u4ntxo0y	29	36	.	.	.
cord-293701-u4ntxo0y	30	1	Given	give	VBN
cord-293701-u4ntxo0y	30	2	that	that	DT
cord-293701-u4ntxo0y	30	3	passive	passive	JJ
cord-293701-u4ntxo0y	30	4	immunization	immunization	NN
cord-293701-u4ntxo0y	30	5	with	with	IN
cord-293701-u4ntxo0y	30	6	feline	feline	JJ
cord-293701-u4ntxo0y	30	7	serum	serum	NN
cord-293701-u4ntxo0y	30	8	containing	contain	VBG
cord-293701-u4ntxo0y	30	9	high	high	JJ
cord-293701-u4ntxo0y	30	10	-	-	HYPH
cord-293701-u4ntxo0y	30	11	titre	titre	NN
cord-293701-u4ntxo0y	30	12	antibodies	antibody	NNS
cord-293701-u4ntxo0y	30	13	reactive	reactive	JJ
cord-293701-u4ntxo0y	30	14	with	with	IN
cord-293701-u4ntxo0y	30	15	feline	feline	JJ
cord-293701-u4ntxo0y	30	16	FIPV	FIPV	NNS
cord-293701-u4ntxo0y	30	17	also	also	RB
cord-293701-u4ntxo0y	30	18	resulted	result	VBD
cord-293701-u4ntxo0y	30	19	in	in	IN
cord-293701-u4ntxo0y	30	20	a	a	DT
cord-293701-u4ntxo0y	30	21	more	more	RBR
cord-293701-u4ntxo0y	30	22	rapid	rapid	JJ
cord-293701-u4ntxo0y	30	23	disease	disease	NN
cord-293701-u4ntxo0y	30	24	after	after	IN
cord-293701-u4ntxo0y	30	25	FIPV	FIPV	NNP
cord-293701-u4ntxo0y	30	26	challenge	challenge	VBP
cord-293701-u4ntxo0y	30	27	26	26	CD
cord-293701-u4ntxo0y	30	28	,	,	,
cord-293701-u4ntxo0y	30	29	the	the	DT
cord-293701-u4ntxo0y	30	30	vaccine	vaccine	NN
cord-293701-u4ntxo0y	30	31	-	-	HYPH
cord-293701-u4ntxo0y	30	32	induced	induce	VBN
cord-293701-u4ntxo0y	30	33	disease	disease	NN
cord-293701-u4ntxo0y	30	34	exacerbation	exacerbation	NN
cord-293701-u4ntxo0y	30	35	may	may	MD
cord-293701-u4ntxo0y	30	36	be	be	VB
cord-293701-u4ntxo0y	30	37	attributed	attribute	VBN
cord-293701-u4ntxo0y	30	38	to	to	IN
cord-293701-u4ntxo0y	30	39	ADE	ADE	NNP
cord-293701-u4ntxo0y	30	40	.	.	.
cord-293701-u4ntxo0y	31	1	Apart	apart	RB
cord-293701-u4ntxo0y	31	2	from	from	IN
cord-293701-u4ntxo0y	31	3	ADE	ADE	NNP
cord-293701-u4ntxo0y	31	4	,	,	,
cord-293701-u4ntxo0y	31	5	type	type	NN
cord-293701-u4ntxo0y	31	6	2	2	CD
cord-293701-u4ntxo0y	31	7	T	t	NN
cord-293701-u4ntxo0y	31	8	helper	helper	NN
cord-293701-u4ntxo0y	31	9	cell	cell	NN
cord-293701-u4ntxo0y	31	10	(	(	-LRB-
cord-293701-u4ntxo0y	31	11	T	T	NNP
cord-293701-u4ntxo0y	31	12	H	h	NN
cord-293701-u4ntxo0y	31	13	2	2	CD
cord-293701-u4ntxo0y	31	14	cell)-based	cell)-base	VBN
cord-293701-u4ntxo0y	31	15	immunopathologic	immunopathologic	JJ
cord-293701-u4ntxo0y	31	16	responses	response	NNS
cord-293701-u4ntxo0y	31	17	induced	induce	VBN
cord-293701-u4ntxo0y	31	18	by	by	IN
cord-293701-u4ntxo0y	31	19	homologous	homologous	JJ
cord-293701-u4ntxo0y	31	20	viral	viral	JJ
cord-293701-u4ntxo0y	31	21	laboratory	laboratory	NN
cord-293701-u4ntxo0y	31	22	or	or	CC
cord-293701-u4ntxo0y	31	23	preclinical	preclinical	JJ
cord-293701-u4ntxo0y	31	24	studies	study	NNS
cord-293701-u4ntxo0y	31	25	5	5	CD
cord-293701-u4ntxo0y	31	26	.	.	.
cord-293701-u4ntxo0y	32	1	The	the	DT
cord-293701-u4ntxo0y	32	2	unprecedented	unprecedented	JJ
cord-293701-u4ntxo0y	32	3	speed	speed	NN
cord-293701-u4ntxo0y	32	4	in	in	IN
cord-293701-u4ntxo0y	32	5	the	the	DT
cord-293701-u4ntxo0y	32	6	development	development	NN
cord-293701-u4ntxo0y	32	7	of	of	IN
cord-293701-u4ntxo0y	32	8	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	32	9	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	32	10	is	be	VBZ
cord-293701-u4ntxo0y	32	11	encouraging	encouraging	JJ
cord-293701-u4ntxo0y	32	12	.	.	.
cord-293701-u4ntxo0y	33	1	However	however	RB
cord-293701-u4ntxo0y	33	2	,	,	,
cord-293701-u4ntxo0y	33	3	we	-PRON-	PRP
cord-293701-u4ntxo0y	33	4	and	and	CC
cord-293701-u4ntxo0y	33	5	others	other	NNS
cord-293701-u4ntxo0y	33	6	have	have	VBP
cord-293701-u4ntxo0y	33	7	raised	raise	VBN
cord-293701-u4ntxo0y	33	8	concerns	concern	NNS
cord-293701-u4ntxo0y	33	9	about	about	IN
cord-293701-u4ntxo0y	33	10	the	the	DT
cord-293701-u4ntxo0y	33	11	safety	safety	NN
cord-293701-u4ntxo0y	33	12	of	of	IN
cord-293701-u4ntxo0y	33	13	some	some	DT
cord-293701-u4ntxo0y	33	14	of	of	IN
cord-293701-u4ntxo0y	33	15	the	the	DT
cord-293701-u4ntxo0y	33	16	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	33	17	vaccine	vaccine	NN
cord-293701-u4ntxo0y	33	18	candidates	candidate	NNS
cord-293701-u4ntxo0y	33	19	6	6	CD
cord-293701-u4ntxo0y	33	20	,	,	,
cord-293701-u4ntxo0y	33	21	7	7	CD
cord-293701-u4ntxo0y	33	22	.	.	.
cord-293701-u4ntxo0y	34	1	A	a	DT
cord-293701-u4ntxo0y	34	2	high	high	JJ
cord-293701-u4ntxo0y	34	3	dose	dose	NN
cord-293701-u4ntxo0y	34	4	of	of	IN
cord-293701-u4ntxo0y	34	5	the	the	DT
cord-293701-u4ntxo0y	34	6	mRNA-1273	mrna-1273	XX
cord-293701-u4ntxo0y	34	7	vaccine	vaccine	NN
cord-293701-u4ntxo0y	34	8	protects	protect	VBZ
cord-293701-u4ntxo0y	34	9	mice	mouse	NNS
cord-293701-u4ntxo0y	34	10	against	against	IN
cord-293701-u4ntxo0y	34	11	infection	infection	NN
cord-293701-u4ntxo0y	34	12	by	by	IN
cord-293701-u4ntxo0y	34	13	mouse	mouse	NN
cord-293701-u4ntxo0y	34	14	-	-	HYPH
cord-293701-u4ntxo0y	34	15	adapted	adapt	VBN
cord-293701-u4ntxo0y	34	16	SARS	SARS	NNP
cord-293701-u4ntxo0y	34	17	-	-	HYPH
cord-293701-u4ntxo0y	34	18	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	34	19	challenge	challenge	NN
cord-293701-u4ntxo0y	34	20	without	without	IN
cord-293701-u4ntxo0y	34	21	enhanced	enhance	VBN
cord-293701-u4ntxo0y	34	22	immunopathology	immunopathology	NN
cord-293701-u4ntxo0y	34	23	8	8	CD
cord-293701-u4ntxo0y	34	24	.	.	.
cord-293701-u4ntxo0y	35	1	PiCoVacc	picovacc	NN
cord-293701-u4ntxo0y	35	2	9	9	CD
cord-293701-u4ntxo0y	35	3	and	and	CC
cord-293701-u4ntxo0y	35	4	BBIBP	BBIBP	NNP
cord-293701-u4ntxo0y	35	5	-	-	HYPH
cord-293701-u4ntxo0y	35	6	CorV	CorV	NNP
cord-293701-u4ntxo0y	35	7	10	10	CD
cord-293701-u4ntxo0y	35	8	elicited	elicit	VBD
cord-293701-u4ntxo0y	35	9	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	35	10	antibodies	antibody	NNS
cord-293701-u4ntxo0y	35	11	(	(	-LRB-
cord-293701-u4ntxo0y	35	12	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	35	13	)	)	-RRB-
cord-293701-u4ntxo0y	35	14	in	in	IN
cord-293701-u4ntxo0y	35	15	mice	mouse	NNS
cord-293701-u4ntxo0y	35	16	,	,	,
cord-293701-u4ntxo0y	35	17	rats	rat	NNS
cord-293701-u4ntxo0y	35	18	and	and	CC
cord-293701-u4ntxo0y	35	19	non	non	JJ
cord-293701-u4ntxo0y	35	20	-	-	JJ
cord-293701-u4ntxo0y	35	21	human	human	JJ
cord-293701-u4ntxo0y	35	22	primates	primate	NNS
cord-293701-u4ntxo0y	35	23	,	,	,
cord-293701-u4ntxo0y	35	24	and	and	CC
cord-293701-u4ntxo0y	35	25	nonhuman	nonhuman	NN
cord-293701-u4ntxo0y	35	26	primates	primate	NNS
cord-293701-u4ntxo0y	35	27	in	in	IN
cord-293701-u4ntxo0y	35	28	the	the	DT
cord-293701-u4ntxo0y	35	29	high	high	JJ
cord-293701-u4ntxo0y	35	30	-	-	HYPH
cord-293701-u4ntxo0y	35	31	dose	dose	NN
cord-293701-u4ntxo0y	35	32	group	group	NN
cord-293701-u4ntxo0y	35	33	were	be	VBD
cord-293701-u4ntxo0y	35	34	fully	fully	RB
cord-293701-u4ntxo0y	35	35	protected	protect	VBN
cord-293701-u4ntxo0y	35	36	from	from	IN
cord-293701-u4ntxo0y	35	37	infection	infection	NN
cord-293701-u4ntxo0y	35	38	by	by	IN
cord-293701-u4ntxo0y	35	39	SARS	SARS	NNP
cord-293701-u4ntxo0y	35	40	-	-	HYPH
cord-293701-u4ntxo0y	35	41	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	35	42	with	with	IN
cord-293701-u4ntxo0y	35	43	no	no	DT
cord-293701-u4ntxo0y	35	44	antibody	antibody	NN
cord-293701-u4ntxo0y	35	45	-	-	HYPH
cord-293701-u4ntxo0y	35	46	dependent	dependent	JJ
cord-293701-u4ntxo0y	35	47	enhancement	enhancement	NN
cord-293701-u4ntxo0y	35	48	(	(	-LRB-
cord-293701-u4ntxo0y	35	49	ADE	ADE	NNP
cord-293701-u4ntxo0y	35	50	)	)	-RRB-
cord-293701-u4ntxo0y	35	51	.	.	.
cord-293701-u4ntxo0y	36	1	The	the	DT
cord-293701-u4ntxo0y	36	2	chimpanzee	chimpanzee	NN
cord-293701-u4ntxo0y	36	3	advenovirus	advenovirus	NN
cord-293701-u4ntxo0y	36	4	-	-	HYPH
cord-293701-u4ntxo0y	36	5	vectored	vectore	VBN
cord-293701-u4ntxo0y	36	6	vaccine	vaccine	NN
cord-293701-u4ntxo0y	36	7	developed	develop	VBN
cord-293701-u4ntxo0y	36	8	by	by	IN
cord-293701-u4ntxo0y	36	9	the	the	DT
cord-293701-u4ntxo0y	36	10	University	University	NNP
cord-293701-u4ntxo0y	36	11	of	of	IN
cord-293701-u4ntxo0y	36	12	Oxford	Oxford	NNP
cord-293701-u4ntxo0y	36	13	and	and	CC
cord-293701-u4ntxo0y	36	14	AstraZeneca	AstraZeneca	NNP
cord-293701-u4ntxo0y	36	15	(	(	-LRB-
cord-293701-u4ntxo0y	36	16	ChAdOx1	ChAdOx1	NNP
cord-293701-u4ntxo0y	36	17	nCoV-19	ncov-19	CD
cord-293701-u4ntxo0y	36	18	)	)	-RRB-
cord-293701-u4ntxo0y	36	19	11	11	CD
cord-293701-u4ntxo0y	36	20	and	and	CC
cord-293701-u4ntxo0y	36	21	a	a	DT
cord-293701-u4ntxo0y	36	22	DNA	dna	NN
cord-293701-u4ntxo0y	36	23	vaccine	vaccine	NN
cord-293701-u4ntxo0y	36	24	12	12	CD
cord-293701-u4ntxo0y	36	25	produced	produce	VBN
cord-293701-u4ntxo0y	36	26	by	by	IN
cord-293701-u4ntxo0y	36	27	Harvard	Harvard	NNP
cord-293701-u4ntxo0y	36	28	Medical	Medical	NNP
cord-293701-u4ntxo0y	36	29	School	School	NNP
cord-293701-u4ntxo0y	36	30	were	be	VBD
cord-293701-u4ntxo0y	36	31	also	also	RB
cord-293701-u4ntxo0y	36	32	effective	effective	JJ
cord-293701-u4ntxo0y	36	33	in	in	IN
cord-293701-u4ntxo0y	36	34	reducing	reduce	VBG
cord-293701-u4ntxo0y	36	35	viral	viral	JJ
cord-293701-u4ntxo0y	36	36	load	load	NN
cord-293701-u4ntxo0y	36	37	in	in	IN
cord-293701-u4ntxo0y	36	38	SARS	SARS	NNP
cord-293701-u4ntxo0y	36	39	-	-	HYPH
cord-293701-u4ntxo0y	36	40	CoV-2-challenged	cov-2-challenge	VBN
cord-293701-u4ntxo0y	36	41	non	non	JJ
cord-293701-u4ntxo0y	36	42	-	-	JJ
cord-293701-u4ntxo0y	36	43	human	human	JJ
cord-293701-u4ntxo0y	36	44	primates	primate	NNS
cord-293701-u4ntxo0y	36	45	without	without	IN
cord-293701-u4ntxo0y	36	46	enhanced	enhance	VBN
cord-293701-u4ntxo0y	36	47	immunopathology	immunopathology	NN
cord-293701-u4ntxo0y	36	48	.	.	.
cord-293701-u4ntxo0y	37	1	So	so	RB
cord-293701-u4ntxo0y	37	2	far	far	RB
cord-293701-u4ntxo0y	37	3	,	,	,
cord-293701-u4ntxo0y	37	4	several	several	JJ
cord-293701-u4ntxo0y	37	5	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	37	6	vaccine	vaccine	NN
cord-293701-u4ntxo0y	37	7	phase	phase	NN
cord-293701-u4ntxo0y	37	8	I	I	NNP
cord-293701-u4ntxo0y	37	9	/	/	SYM
cord-293701-u4ntxo0y	37	10	II	II	NNP
cord-293701-u4ntxo0y	37	11	clinical	clinical	JJ
cord-293701-u4ntxo0y	37	12	trials	trial	NNS
cord-293701-u4ntxo0y	37	13	have	have	VBP
cord-293701-u4ntxo0y	37	14	been	be	VBN
cord-293701-u4ntxo0y	37	15	completed	complete	VBN
cord-293701-u4ntxo0y	37	16	,	,	,
cord-293701-u4ntxo0y	37	17	including	include	VBG
cord-293701-u4ntxo0y	37	18	trials	trial	NNS
cord-293701-u4ntxo0y	37	19	of	of	IN
cord-293701-u4ntxo0y	37	20	Ad5-nCoV	Ad5-nCoV	NNP
cord-293701-u4ntxo0y	37	21	3	3	CD
cord-293701-u4ntxo0y	37	22	,	,	,
cord-293701-u4ntxo0y	37	23	mRNA-1273	mRNA-1273	NNP
cord-293701-u4ntxo0y	37	24	(	(	-LRB-
cord-293701-u4ntxo0y	37	25	ref	ref	NN
cord-293701-u4ntxo0y	37	26	.	.	NNP
cord-293701-u4ntxo0y	37	27	2	2	LS
cord-293701-u4ntxo0y	37	28	)	)	-RRB-
cord-293701-u4ntxo0y	37	29	,	,	,
cord-293701-u4ntxo0y	37	30	ChAdOx1	ChAdOx1	NNP
cord-293701-u4ntxo0y	37	31	nCoV-19	nCoV-19	NNP
cord-293701-u4ntxo0y	37	32	(	(	-LRB-
cord-293701-u4ntxo0y	37	33	ref	ref	NN
cord-293701-u4ntxo0y	37	34	.	.	NNP
cord-293701-u4ntxo0y	37	35	13	13	CD
cord-293701-u4ntxo0y	37	36	)	)	-RRB-
cord-293701-u4ntxo0y	37	37	and	and	CC
cord-293701-u4ntxo0y	37	38	an	an	DT
cord-293701-u4ntxo0y	37	39	mRNA	mRNA	NNP
cord-293701-u4ntxo0y	37	40	vaccine	vaccine	NN
cord-293701-u4ntxo0y	37	41	developed	develop	VBN
cord-293701-u4ntxo0y	37	42	by	by	IN
cord-293701-u4ntxo0y	37	43	Pfizer	Pfizer	NNP
cord-293701-u4ntxo0y	37	44	and	and	CC
cord-293701-u4ntxo0y	37	45	BioNTech	BioNTech	NNP
cord-293701-u4ntxo0y	37	46	(	(	-LRB-
cord-293701-u4ntxo0y	37	47	BNT162b1	bnt162b1	CD
cord-293701-u4ntxo0y	37	48	)	)	-RRB-
cord-293701-u4ntxo0y	37	49	14	14	CD
cord-293701-u4ntxo0y	37	50	.	.	.
cord-293701-u4ntxo0y	38	1	According	accord	VBG
cord-293701-u4ntxo0y	38	2	to	to	IN
cord-293701-u4ntxo0y	38	3	the	the	DT
cord-293701-u4ntxo0y	38	4	reported	report	VBN
cord-293701-u4ntxo0y	38	5	challenge	challenge	NN
cord-293701-u4ntxo0y	38	6	after	after	IN
cord-293701-u4ntxo0y	38	7	vaccination	vaccination	NN
cord-293701-u4ntxo0y	38	8	could	could	MD
cord-293701-u4ntxo0y	38	9	also	also	RB
cord-293701-u4ntxo0y	38	10	result	result	VB
cord-293701-u4ntxo0y	38	11	in	in	IN
cord-293701-u4ntxo0y	38	12	disease	disease	NN
cord-293701-u4ntxo0y	38	13	exacerbation	exacerbation	NN
cord-293701-u4ntxo0y	38	14	27	27	CD
cord-293701-u4ntxo0y	38	15	.	.	.
cord-293701-u4ntxo0y	39	1	In	in	IN
cord-293701-u4ntxo0y	39	2	this	this	DT
cord-293701-u4ntxo0y	39	3	Perspective	perspective	NN
cord-293701-u4ntxo0y	39	4	,	,	,
cord-293701-u4ntxo0y	39	5	we	-PRON-	PRP
cord-293701-u4ntxo0y	39	6	use	use	VBP
cord-293701-u4ntxo0y	39	7	the	the	DT
cord-293701-u4ntxo0y	39	8	term	term	NN
cord-293701-u4ntxo0y	39	9	'	'	``
cord-293701-u4ntxo0y	39	10	vaccine	vaccine	NN
cord-293701-u4ntxo0y	39	11	-	-	HYPH
cord-293701-u4ntxo0y	39	12	associated	associate	VBN
cord-293701-u4ntxo0y	39	13	disease	disease	NN
cord-293701-u4ntxo0y	39	14	enhancement	enhancement	NN
cord-293701-u4ntxo0y	39	15	'	'	''
cord-293701-u4ntxo0y	39	16	(	(	-LRB-
cord-293701-u4ntxo0y	39	17	VADE	VADE	NNP
cord-293701-u4ntxo0y	39	18	;	;	:
cord-293701-u4ntxo0y	39	19	Box	Box	NNP
cord-293701-u4ntxo0y	39	20	1	1	CD
cord-293701-u4ntxo0y	39	21	)	)	-RRB-
cord-293701-u4ntxo0y	39	22	to	to	TO
cord-293701-u4ntxo0y	39	23	describe	describe	VB
cord-293701-u4ntxo0y	39	24	both	both	DT
cord-293701-u4ntxo0y	39	25	antibodydependent	antibodydependent	NN
cord-293701-u4ntxo0y	39	26	and	and	CC
cord-293701-u4ntxo0y	39	27	T	T	NNP
cord-293701-u4ntxo0y	39	28	H	h	NN
cord-293701-u4ntxo0y	39	29	2	2	CD
cord-293701-u4ntxo0y	39	30	cell	cell	NN
cord-293701-u4ntxo0y	39	31	-	-	HYPH
cord-293701-u4ntxo0y	39	32	dependent	dependent	JJ
cord-293701-u4ntxo0y	39	33	disease	disease	NN
cord-293701-u4ntxo0y	39	34	exacerbation	exacerbation	NN
cord-293701-u4ntxo0y	39	35	(	(	-LRB-
cord-293701-u4ntxo0y	39	36	fig	fig	NN
cord-293701-u4ntxo0y	39	37	.	.	NNP
cord-293701-u4ntxo0y	39	38	1	1	CD
cord-293701-u4ntxo0y	39	39	)	)	-RRB-
cord-293701-u4ntxo0y	39	40	.	.	.
cord-293701-u4ntxo0y	40	1	We	-PRON-	PRP
cord-293701-u4ntxo0y	40	2	summarize	summarize	VBP
cord-293701-u4ntxo0y	40	3	examples	example	NNS
cord-293701-u4ntxo0y	40	4	of	of	IN
cord-293701-u4ntxo0y	40	5	VADE	VADE	NNP
cord-293701-u4ntxo0y	40	6	in	in	IN
cord-293701-u4ntxo0y	40	7	the	the	DT
cord-293701-u4ntxo0y	40	8	history	history	NN
cord-293701-u4ntxo0y	40	9	of	of	IN
cord-293701-u4ntxo0y	40	10	the	the	DT
cord-293701-u4ntxo0y	40	11	development	development	NN
cord-293701-u4ntxo0y	40	12	of	of	IN
cord-293701-u4ntxo0y	40	13	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	40	14	against	against	IN
cord-293701-u4ntxo0y	40	15	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	40	16	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	40	17	virus	virus	NN
cord-293701-u4ntxo0y	40	18	(	(	-LRB-
cord-293701-u4ntxo0y	40	19	RSV	RSV	NNP
cord-293701-u4ntxo0y	40	20	)	)	-RRB-
cord-293701-u4ntxo0y	40	21	,	,	,
cord-293701-u4ntxo0y	40	22	dengue	dengue	NN
cord-293701-u4ntxo0y	40	23	virus	virus	NN
cord-293701-u4ntxo0y	40	24	(	(	-LRB-
cord-293701-u4ntxo0y	40	25	DENV	DENV	NNP
cord-293701-u4ntxo0y	40	26	)	)	-RRB-
cord-293701-u4ntxo0y	40	27	,	,	,
cord-293701-u4ntxo0y	40	28	SARS	SARS	NNP
cord-293701-u4ntxo0y	40	29	-	-	HYPH
cord-293701-u4ntxo0y	40	30	CoV	CoV	NNP
cord-293701-u4ntxo0y	40	31	and	and	CC
cord-293701-u4ntxo0y	40	32	Middle	Middle	NNP
cord-293701-u4ntxo0y	40	33	East	East	NNP
cord-293701-u4ntxo0y	40	34	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	40	35	syndrome	syndrome	NN
cord-293701-u4ntxo0y	40	36	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	40	37	(	(	-LRB-
cord-293701-u4ntxo0y	40	38	MERS	MERS	NNP
cord-293701-u4ntxo0y	40	39	-	-	HYPH
cord-293701-u4ntxo0y	40	40	CoV	CoV	NNP
cord-293701-u4ntxo0y	40	41	)	)	-RRB-
cord-293701-u4ntxo0y	40	42	,	,	,
cord-293701-u4ntxo0y	40	43	each	each	DT
cord-293701-u4ntxo0y	40	44	of	of	IN
cord-293701-u4ntxo0y	40	45	which	which	WDT
cord-293701-u4ntxo0y	40	46	provides	provide	VBZ
cord-293701-u4ntxo0y	40	47	clues	clue	NNS
cord-293701-u4ntxo0y	40	48	for	for	IN
cord-293701-u4ntxo0y	40	49	safe	safe	JJ
cord-293701-u4ntxo0y	40	50	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	40	51	vaccine	vaccine	NN
cord-293701-u4ntxo0y	40	52	development	development	NN
cord-293701-u4ntxo0y	40	53	and	and	CC
cord-293701-u4ntxo0y	40	54	highlights	highlight	VBZ
cord-293701-u4ntxo0y	40	55	the	the	DT
cord-293701-u4ntxo0y	40	56	need	need	NN
cord-293701-u4ntxo0y	40	57	for	for	IN
cord-293701-u4ntxo0y	40	58	rigorous	rigorous	JJ
cord-293701-u4ntxo0y	40	59	preclinical	preclinical	JJ
cord-293701-u4ntxo0y	40	60	and	and	CC
cord-293701-u4ntxo0y	40	61	clinical	clinical	JJ
cord-293701-u4ntxo0y	40	62	safety	safety	NN
cord-293701-u4ntxo0y	40	63	testing	testing	NN
cord-293701-u4ntxo0y	40	64	.	.	.
cord-293701-u4ntxo0y	41	1	There	there	EX
cord-293701-u4ntxo0y	41	2	have	have	VBP
cord-293701-u4ntxo0y	41	3	been	be	VBN
cord-293701-u4ntxo0y	41	4	warnings	warning	NNS
cord-293701-u4ntxo0y	41	5	that	that	IN
cord-293701-u4ntxo0y	41	6	ADE	ADE	NNP
cord-293701-u4ntxo0y	41	7	should	should	MD
cord-293701-u4ntxo0y	41	8	be	be	VB
cord-293701-u4ntxo0y	41	9	fully	fully	RB
cord-293701-u4ntxo0y	41	10	evaluated	evaluate	VBN
cord-293701-u4ntxo0y	41	11	for	for	IN
cord-293701-u4ntxo0y	41	12	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	41	13	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	41	14	to	to	TO
cord-293701-u4ntxo0y	41	15	avoid	avoid	VB
cord-293701-u4ntxo0y	41	16	repeating	repeat	VBG
cord-293701-u4ntxo0y	41	17	the	the	DT
cord-293701-u4ntxo0y	41	18	tragic	tragic	JJ
cord-293701-u4ntxo0y	41	19	failure	failure	NN
cord-293701-u4ntxo0y	41	20	of	of	IN
cord-293701-u4ntxo0y	41	21	the	the	DT
cord-293701-u4ntxo0y	41	22	RSV	RSV	NNP
cord-293701-u4ntxo0y	41	23	vaccine	vaccine	NN
cord-293701-u4ntxo0y	41	24	28	28	CD
cord-293701-u4ntxo0y	41	25	.	.	.
cord-293701-u4ntxo0y	42	1	The	the	DT
cord-293701-u4ntxo0y	42	2	first	first	JJ
cord-293701-u4ntxo0y	42	3	RSV	RSV	NNP
cord-293701-u4ntxo0y	42	4	vaccine	vaccine	NN
cord-293701-u4ntxo0y	42	5	,	,	,
cord-293701-u4ntxo0y	42	6	based	base	VBN
cord-293701-u4ntxo0y	42	7	on	on	IN
cord-293701-u4ntxo0y	42	8	formalin	formalin	NN
cord-293701-u4ntxo0y	42	9	-	-	HYPH
cord-293701-u4ntxo0y	42	10	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	42	11	RSV	RSV	NNP
cord-293701-u4ntxo0y	42	12	(	(	-LRB-
cord-293701-u4ntxo0y	42	13	FI	FI	NNP
cord-293701-u4ntxo0y	42	14	-	-	HYPH
cord-293701-u4ntxo0y	42	15	RSV	RSV	NNP
cord-293701-u4ntxo0y	42	16	)	)	-RRB-
cord-293701-u4ntxo0y	42	17	,	,	,
cord-293701-u4ntxo0y	42	18	entered	enter	VBD
cord-293701-u4ntxo0y	42	19	a	a	DT
cord-293701-u4ntxo0y	42	20	clinical	clinical	JJ
cord-293701-u4ntxo0y	42	21	trial	trial	NN
cord-293701-u4ntxo0y	42	22	in	in	IN
cord-293701-u4ntxo0y	42	23	1965	1965	CD
cord-293701-u4ntxo0y	42	24	,	,	,
cord-293701-u4ntxo0y	42	25	a	a	DT
cord-293701-u4ntxo0y	42	26	time	time	NN
cord-293701-u4ntxo0y	42	27	when	when	WRB
cord-293701-u4ntxo0y	42	28	several	several	JJ
cord-293701-u4ntxo0y	42	29	other	other	JJ
cord-293701-u4ntxo0y	42	30	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	42	31	or	or	CC
cord-293701-u4ntxo0y	42	32	attenuated	attenuated	JJ
cord-293701-u4ntxo0y	42	33	virus	virus	NN
cord-293701-u4ntxo0y	42	34	-	-	HYPH
cord-293701-u4ntxo0y	42	35	based	base	VBN
cord-293701-u4ntxo0y	42	36	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	42	37	had	have	VBD
cord-293701-u4ntxo0y	42	38	already	already	RB
cord-293701-u4ntxo0y	42	39	been	be	VBN
cord-293701-u4ntxo0y	42	40	successfully	successfully	RB
cord-293701-u4ntxo0y	42	41	developed	develop	VBN
cord-293701-u4ntxo0y	42	42	,	,	,
cord-293701-u4ntxo0y	42	43	such	such	JJ
cord-293701-u4ntxo0y	42	44	as	as	IN
cord-293701-u4ntxo0y	42	45	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	42	46	against	against	IN
cord-293701-u4ntxo0y	42	47	smallpox	smallpox	NN
cord-293701-u4ntxo0y	42	48	29	29	CD
cord-293701-u4ntxo0y	42	49	and	and	CC
cord-293701-u4ntxo0y	42	50	polio	polio	NN
cord-293701-u4ntxo0y	42	51	30	30	CD
cord-293701-u4ntxo0y	42	52	.	.	.
cord-293701-u4ntxo0y	43	1	The	the	DT
cord-293701-u4ntxo0y	43	2	FI	FI	NNP
cord-293701-u4ntxo0y	43	3	-	-	HYPH
cord-293701-u4ntxo0y	43	4	RSV	RSV	NNP
cord-293701-u4ntxo0y	43	5	vaccine	vaccine	NN
cord-293701-u4ntxo0y	43	6	was	be	VBD
cord-293701-u4ntxo0y	43	7	well	well	RB
cord-293701-u4ntxo0y	43	8	tolerated	tolerate	VBN
cord-293701-u4ntxo0y	43	9	and	and	CC
cord-293701-u4ntxo0y	43	10	appeared	appear	VBD
cord-293701-u4ntxo0y	43	11	to	to	TO
cord-293701-u4ntxo0y	43	12	be	be	VB
cord-293701-u4ntxo0y	43	13	moderately	moderately	RB
cord-293701-u4ntxo0y	43	14	immunogenic	immunogenic	JJ
cord-293701-u4ntxo0y	43	15	at	at	IN
cord-293701-u4ntxo0y	43	16	first	first	RB
cord-293701-u4ntxo0y	43	17	.	.	.
cord-293701-u4ntxo0y	44	1	However	however	RB
cord-293701-u4ntxo0y	44	2	,	,	,
cord-293701-u4ntxo0y	44	3	instead	instead	RB
cord-293701-u4ntxo0y	44	4	of	of	IN
cord-293701-u4ntxo0y	44	5	protecting	protect	VBG
cord-293701-u4ntxo0y	44	6	study	study	NN
cord-293701-u4ntxo0y	44	7	participants	participant	NNS
cord-293701-u4ntxo0y	44	8	,	,	,
cord-293701-u4ntxo0y	44	9	the	the	DT
cord-293701-u4ntxo0y	44	10	FI	FI	NNP
cord-293701-u4ntxo0y	44	11	-	-	HYPH
cord-293701-u4ntxo0y	44	12	RSV	RSV	NNP
cord-293701-u4ntxo0y	44	13	vaccine	vaccine	NN
cord-293701-u4ntxo0y	44	14	exhibited	exhibit	VBD
cord-293701-u4ntxo0y	44	15	a	a	DT
cord-293701-u4ntxo0y	44	16	paradoxical	paradoxical	JJ
cord-293701-u4ntxo0y	44	17	disease	disease	NN
cord-293701-u4ntxo0y	44	18	-	-	HYPH
cord-293701-u4ntxo0y	44	19	strengthening	strengthen	VBG
cord-293701-u4ntxo0y	44	20	effect	effect	NN
cord-293701-u4ntxo0y	44	21	(	(	-LRB-
cord-293701-u4ntxo0y	44	22	enhanced	enhanced	JJ
cord-293701-u4ntxo0y	44	23	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	44	24	disease	disease	NN
cord-293701-u4ntxo0y	44	25	(	(	-LRB-
cord-293701-u4ntxo0y	44	26	ERD	ERD	NNP
cord-293701-u4ntxo0y	44	27	)	)	-RRB-
cord-293701-u4ntxo0y	44	28	;	;	:
cord-293701-u4ntxo0y	44	29	Box	Box	NNP
cord-293701-u4ntxo0y	44	30	1	1	CD
cord-293701-u4ntxo0y	44	31	)	)	-RRB-
cord-293701-u4ntxo0y	44	32	during	during	IN
cord-293701-u4ntxo0y	44	33	subsequent	subsequent	JJ
cord-293701-u4ntxo0y	44	34	natural	natural	JJ
cord-293701-u4ntxo0y	44	35	RSV	RSV	NNP
cord-293701-u4ntxo0y	44	36	infection	infection	NN
cord-293701-u4ntxo0y	44	37	.	.	.
cord-293701-u4ntxo0y	45	1	Among	among	IN
cord-293701-u4ntxo0y	45	2	the	the	DT
cord-293701-u4ntxo0y	45	3	20	20	CD
cord-293701-u4ntxo0y	45	4	infants	infant	NNS
cord-293701-u4ntxo0y	45	5	who	who	WP
cord-293701-u4ntxo0y	45	6	received	receive	VBD
cord-293701-u4ntxo0y	45	7	the	the	DT
cord-293701-u4ntxo0y	45	8	FI	FI	NNP
cord-293701-u4ntxo0y	45	9	-	-	HYPH
cord-293701-u4ntxo0y	45	10	RSV	RSV	NNP
cord-293701-u4ntxo0y	45	11	vaccine	vaccine	NN
cord-293701-u4ntxo0y	45	12	,	,	,
cord-293701-u4ntxo0y	45	13	16	16	CD
cord-293701-u4ntxo0y	45	14	required	require	VBN
cord-293701-u4ntxo0y	45	15	hospitalization	hospitalization	NN
cord-293701-u4ntxo0y	45	16	,	,	,
cord-293701-u4ntxo0y	45	17	including	include	VBG
cord-293701-u4ntxo0y	45	18	two	two	CD
cord-293701-u4ntxo0y	45	19	who	who	WP
cord-293701-u4ntxo0y	45	20	subsequently	subsequently	RB
cord-293701-u4ntxo0y	45	21	died	die	VBD
cord-293701-u4ntxo0y	45	22	,	,	,
cord-293701-u4ntxo0y	45	23	whereas	whereas	IN
cord-293701-u4ntxo0y	45	24	only	only	RB
cord-293701-u4ntxo0y	45	25	one	one	CD
cord-293701-u4ntxo0y	45	26	of	of	IN
cord-293701-u4ntxo0y	45	27	the	the	DT
cord-293701-u4ntxo0y	45	28	21	21	CD
cord-293701-u4ntxo0y	45	29	participants	participant	NNS
cord-293701-u4ntxo0y	45	30	in	in	IN
cord-293701-u4ntxo0y	45	31	the	the	DT
cord-293701-u4ntxo0y	45	32	control	control	NN
cord-293701-u4ntxo0y	45	33	group	group	NN
cord-293701-u4ntxo0y	45	34	was	be	VBD
cord-293701-u4ntxo0y	45	35	hospitalized	hospitalize	VBN
cord-293701-u4ntxo0y	45	36	31	31	CD
cord-293701-u4ntxo0y	45	37	.	.	.
cord-293701-u4ntxo0y	46	1	The	the	DT
cord-293701-u4ntxo0y	46	2	FDA	FDA	NNP
cord-293701-u4ntxo0y	46	3	then	then	RB
cord-293701-u4ntxo0y	46	4	urgently	urgently	RB
cord-293701-u4ntxo0y	46	5	suspended	suspend	VBD
cord-293701-u4ntxo0y	46	6	all	all	DT
cord-293701-u4ntxo0y	46	7	clinical	clinical	JJ
cord-293701-u4ntxo0y	46	8	studies	study	NNS
cord-293701-u4ntxo0y	46	9	of	of	IN
cord-293701-u4ntxo0y	46	10	RSV	RSV	NNP
cord-293701-u4ntxo0y	46	11	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	46	12	.	.	.
cord-293701-u4ntxo0y	47	1	To	to	TO
cord-293701-u4ntxo0y	47	2	elucidate	elucidate	VB
cord-293701-u4ntxo0y	47	3	the	the	DT
cord-293701-u4ntxo0y	47	4	mechanism	mechanism	NN
cord-293701-u4ntxo0y	47	5	of	of	IN
cord-293701-u4ntxo0y	47	6	ERD	ERD	NNP
cord-293701-u4ntxo0y	47	7	in	in	IN
cord-293701-u4ntxo0y	47	8	this	this	DT
cord-293701-u4ntxo0y	47	9	RSV	RSV	NNP
cord-293701-u4ntxo0y	47	10	vaccine	vaccine	NN
cord-293701-u4ntxo0y	47	11	trial	trial	NN
cord-293701-u4ntxo0y	47	12	,	,	,
cord-293701-u4ntxo0y	47	13	the	the	DT
cord-293701-u4ntxo0y	47	14	humoral	humoral	JJ
cord-293701-u4ntxo0y	47	15	and	and	CC
cord-293701-u4ntxo0y	47	16	cellular	cellular	JJ
cord-293701-u4ntxo0y	47	17	immune	immune	JJ
cord-293701-u4ntxo0y	47	18	responses	response	NNS
cord-293701-u4ntxo0y	47	19	after	after	IN
cord-293701-u4ntxo0y	47	20	FI	FI	NNP
cord-293701-u4ntxo0y	47	21	-	-	HYPH
cord-293701-u4ntxo0y	47	22	RSV	RSV	NNP
cord-293701-u4ntxo0y	47	23	inoculation	inoculation	NN
cord-293701-u4ntxo0y	47	24	were	be	VBD
cord-293701-u4ntxo0y	47	25	analysed	analyse	VBN
cord-293701-u4ntxo0y	47	26	.	.	.
cord-293701-u4ntxo0y	48	1	FI	FI	NNP
cord-293701-u4ntxo0y	48	2	-	-	HYPH
cord-293701-u4ntxo0y	48	3	RSV	RSV	NNP
cord-293701-u4ntxo0y	48	4	induced	induce	VBN
cord-293701-u4ntxo0y	48	5	RSV	RSV	NNP
cord-293701-u4ntxo0y	48	6	glycoprotein	glycoprotein	NN
cord-293701-u4ntxo0y	48	7	binding	bind	VBG
cord-293701-u4ntxo0y	48	8	,	,	,
cord-293701-u4ntxo0y	48	9	but	but	CC
cord-293701-u4ntxo0y	48	10	not	not	RB
cord-293701-u4ntxo0y	48	11	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	48	12	,	,	,
cord-293701-u4ntxo0y	48	13	eosinophilia	eosinophilia	NN
cord-293701-u4ntxo0y	48	14	and	and	CC
cord-293701-u4ntxo0y	48	15	an	an	DT
cord-293701-u4ntxo0y	48	16	exaggerated	exaggerated	JJ
cord-293701-u4ntxo0y	48	17	CD4	CD4	NNP
cord-293701-u4ntxo0y	48	18	+	+	CC
cord-293701-u4ntxo0y	48	19	T	T	NNP
cord-293701-u4ntxo0y	48	20	cell	cell	NN
cord-293701-u4ntxo0y	48	21	response	response	NN
cord-293701-u4ntxo0y	48	22	32	32	CD
cord-293701-u4ntxo0y	48	23	,	,	,
cord-293701-u4ntxo0y	48	24	33	33	CD
cord-293701-u4ntxo0y	48	25	.	.	.
cord-293701-u4ntxo0y	49	1	It	-PRON-	PRP
cord-293701-u4ntxo0y	49	2	was	be	VBD
cord-293701-u4ntxo0y	49	3	not	not	RB
cord-293701-u4ntxo0y	49	4	until	until	IN
cord-293701-u4ntxo0y	49	5	the	the	DT
cord-293701-u4ntxo0y	49	6	1990s	1990	NNS
cord-293701-u4ntxo0y	49	7	,	,	,
cord-293701-u4ntxo0y	49	8	three	three	CD
cord-293701-u4ntxo0y	49	9	decades	decade	NNS
cord-293701-u4ntxo0y	49	10	after	after	IN
cord-293701-u4ntxo0y	49	11	the	the	DT
cord-293701-u4ntxo0y	49	12	first	first	JJ
cord-293701-u4ntxo0y	49	13	FI	FI	NNP
cord-293701-u4ntxo0y	49	14	-	-	HYPH
cord-293701-u4ntxo0y	49	15	RSV	RSV	NNP
cord-293701-u4ntxo0y	49	16	trial	trial	NN
cord-293701-u4ntxo0y	49	17	,	,	,
cord-293701-u4ntxo0y	49	18	that	that	IN
cord-293701-u4ntxo0y	49	19	an	an	DT
cord-293701-u4ntxo0y	49	20	enhanced	enhanced	JJ
cord-293701-u4ntxo0y	49	21	inflammatory	inflammatory	JJ
cord-293701-u4ntxo0y	49	22	response	response	NN
cord-293701-u4ntxo0y	49	23	to	to	IN
cord-293701-u4ntxo0y	49	24	the	the	DT
cord-293701-u4ntxo0y	49	25	vaccine	vaccine	NN
cord-293701-u4ntxo0y	49	26	was	be	VBD
cord-293701-u4ntxo0y	49	27	identified	identify	VBN
cord-293701-u4ntxo0y	49	28	,	,	,
cord-293701-u4ntxo0y	49	29	consisting	consist	VBG
cord-293701-u4ntxo0y	49	30	of	of	IN
cord-293701-u4ntxo0y	49	31	a	a	DT
cord-293701-u4ntxo0y	49	32	T	t	NN
cord-293701-u4ntxo0y	49	33	H	h	NN
cord-293701-u4ntxo0y	49	34	2	2	CD
cord-293701-u4ntxo0y	49	35	cell	cell	NN
cord-293701-u4ntxo0y	49	36	-	-	HYPH
cord-293701-u4ntxo0y	49	37	skewed	skewed	JJ
cord-293701-u4ntxo0y	49	38	T	t	NN
cord-293701-u4ntxo0y	49	39	cell	cell	NN
cord-293701-u4ntxo0y	49	40	response	response	NN
cord-293701-u4ntxo0y	49	41	,	,	,
cord-293701-u4ntxo0y	49	42	which	which	WDT
cord-293701-u4ntxo0y	49	43	contributed	contribute	VBD
cord-293701-u4ntxo0y	49	44	to	to	IN
cord-293701-u4ntxo0y	49	45	the	the	DT
cord-293701-u4ntxo0y	49	46	exaggerated	exaggerated	JJ
cord-293701-u4ntxo0y	49	47	proliferation	proliferation	NN
cord-293701-u4ntxo0y	49	48	of	of	IN
cord-293701-u4ntxo0y	49	49	CD4	CD4	NNP
cord-293701-u4ntxo0y	49	50	+	+	CC
cord-293701-u4ntxo0y	49	51	T	T	NNP
cord-293701-u4ntxo0y	49	52	cells	cell	NNS
cord-293701-u4ntxo0y	49	53	and	and	CC
cord-293701-u4ntxo0y	49	54	eosinophils	eosinophil	VBD
cord-293701-u4ntxo0y	49	55	27	27	CD
cord-293701-u4ntxo0y	49	56	,	,	,
cord-293701-u4ntxo0y	49	57	34	34	CD
cord-293701-u4ntxo0y	49	58	,	,	,
cord-293701-u4ntxo0y	49	59	35	35	CD
cord-293701-u4ntxo0y	49	60	.	.	.
cord-293701-u4ntxo0y	50	1	This	this	DT
cord-293701-u4ntxo0y	50	2	T	t	NN
cord-293701-u4ntxo0y	50	3	H	h	NN
cord-293701-u4ntxo0y	50	4	2	2	CD
cord-293701-u4ntxo0y	50	5	cell	cell	NN
cord-293701-u4ntxo0y	50	6	-	-	HYPH
cord-293701-u4ntxo0y	50	7	skewed	skewed	JJ
cord-293701-u4ntxo0y	50	8	pattern	pattern	NN
cord-293701-u4ntxo0y	50	9	led	lead	VBN
cord-293701-u4ntxo0y	50	10	to	to	IN
cord-293701-u4ntxo0y	50	11	poor	poor	JJ
cord-293701-u4ntxo0y	50	12	stimulation	stimulation	NN
cord-293701-u4ntxo0y	50	13	of	of	IN
cord-293701-u4ntxo0y	50	14	natural	natural	JJ
cord-293701-u4ntxo0y	50	15	killer	killer	NN
cord-293701-u4ntxo0y	50	16	cells	cell	NNS
cord-293701-u4ntxo0y	50	17	and	and	CC
cord-293701-u4ntxo0y	50	18	CD8	CD8	NNP
cord-293701-u4ntxo0y	50	19	+	+	CC
cord-293701-u4ntxo0y	50	20	cytotoxic	cytotoxic	JJ
cord-293701-u4ntxo0y	50	21	T	t	NN
cord-293701-u4ntxo0y	50	22	lymphocytes	lymphocyte	NNS
cord-293701-u4ntxo0y	50	23	,	,	,
cord-293701-u4ntxo0y	50	24	which	which	WDT
cord-293701-u4ntxo0y	50	25	otherwise	otherwise	RB
cord-293701-u4ntxo0y	50	26	are	be	VBP
cord-293701-u4ntxo0y	50	27	able	able	JJ
cord-293701-u4ntxo0y	50	28	to	to	TO
cord-293701-u4ntxo0y	50	29	prevent	prevent	VB
cord-293701-u4ntxo0y	50	30	T	T	NNP
cord-293701-u4ntxo0y	50	31	H	h	NN
cord-293701-u4ntxo0y	50	32	2	2	CD
cord-293701-u4ntxo0y	50	33	cell	cell	NN
cord-293701-u4ntxo0y	50	34	and	and	CC
cord-293701-u4ntxo0y	50	35	inflammatory	inflammatory	JJ
cord-293701-u4ntxo0y	50	36	responses	response	NNS
cord-293701-u4ntxo0y	50	37	to	to	IN
cord-293701-u4ntxo0y	50	38	RSV	RSV	NNP
cord-293701-u4ntxo0y	50	39	antigens	antigen	NNS
cord-293701-u4ntxo0y	50	40	36	36	CD
cord-293701-u4ntxo0y	50	41	,	,	,
cord-293701-u4ntxo0y	50	42	37	37	CD
cord-293701-u4ntxo0y	50	43	.	.	.
cord-293701-u4ntxo0y	51	1	Recent	recent	JJ
cord-293701-u4ntxo0y	51	2	work	work	NN
cord-293701-u4ntxo0y	51	3	suggested	suggest	VBD
cord-293701-u4ntxo0y	51	4	that	that	IN
cord-293701-u4ntxo0y	51	5	the	the	DT
cord-293701-u4ntxo0y	51	6	carbonyl	carbonyl	NN
cord-293701-u4ntxo0y	51	7	groups	group	NNS
cord-293701-u4ntxo0y	51	8	caused	cause	VBN
cord-293701-u4ntxo0y	51	9	by	by	IN
cord-293701-u4ntxo0y	51	10	formalin	formalin	NN
cord-293701-u4ntxo0y	51	11	fixation	fixation	NN
cord-293701-u4ntxo0y	51	12	created	create	VBD
cord-293701-u4ntxo0y	51	13	the	the	DT
cord-293701-u4ntxo0y	51	14	enhanced	enhanced	JJ
cord-293701-u4ntxo0y	51	15	T	t	NN
cord-293701-u4ntxo0y	51	16	H	h	NN
cord-293701-u4ntxo0y	51	17	2	2	CD
cord-293701-u4ntxo0y	51	18	cell	cell	NN
cord-293701-u4ntxo0y	51	19	response	response	NN
cord-293701-u4ntxo0y	51	20	38	38	CD
cord-293701-u4ntxo0y	51	21	.	.	.
cord-293701-u4ntxo0y	52	1	However	however	RB
cord-293701-u4ntxo0y	52	2	,	,	,
cord-293701-u4ntxo0y	52	3	ERD	ERD	NNP
cord-293701-u4ntxo0y	52	4	was	be	VBD
cord-293701-u4ntxo0y	52	5	also	also	RB
cord-293701-u4ntxo0y	52	6	observed	observe	VBN
cord-293701-u4ntxo0y	52	7	in	in	IN
cord-293701-u4ntxo0y	52	8	experimental	experimental	JJ
cord-293701-u4ntxo0y	52	9	animals	animal	NNS
cord-293701-u4ntxo0y	52	10	immunized	immunize	VBN
cord-293701-u4ntxo0y	52	11	with	with	IN
cord-293701-u4ntxo0y	52	12	purified	purify	VBN
cord-293701-u4ntxo0y	52	13	RSV	RSV	NNP
cord-293701-u4ntxo0y	52	14	F	F	NNP
cord-293701-u4ntxo0y	52	15	and	and	CC
cord-293701-u4ntxo0y	52	16	G	g	NN
cord-293701-u4ntxo0y	52	17	glycoproteins	glycoprotein	NNS
cord-293701-u4ntxo0y	52	18	that	that	WDT
cord-293701-u4ntxo0y	52	19	were	be	VBD
cord-293701-u4ntxo0y	52	20	not	not	RB
cord-293701-u4ntxo0y	52	21	fixed	fix	VBN
cord-293701-u4ntxo0y	52	22	with	with	IN
cord-293701-u4ntxo0y	52	23	formalin	formalin	NN
cord-293701-u4ntxo0y	52	24	39	39	CD
cord-293701-u4ntxo0y	52	25	,	,	,
cord-293701-u4ntxo0y	52	26	40	40	CD
cord-293701-u4ntxo0y	52	27	,	,	,
cord-293701-u4ntxo0y	52	28	suggesting	suggest	VBG
cord-293701-u4ntxo0y	52	29	that	that	IN
cord-293701-u4ntxo0y	52	30	formalin	formalin	NN
cord-293701-u4ntxo0y	52	31	fixation	fixation	NN
cord-293701-u4ntxo0y	52	32	was	be	VBD
cord-293701-u4ntxo0y	52	33	not	not	RB
cord-293701-u4ntxo0y	52	34	the	the	DT
cord-293701-u4ntxo0y	52	35	determinant	determinant	NN
cord-293701-u4ntxo0y	52	36	for	for	IN
cord-293701-u4ntxo0y	52	37	pathogenic	pathogenic	JJ
cord-293701-u4ntxo0y	52	38	inflammation	inflammation	NN
cord-293701-u4ntxo0y	52	39	.	.	.
cord-293701-u4ntxo0y	53	1	Previous	previous	JJ
cord-293701-u4ntxo0y	53	2	studies	study	NNS
cord-293701-u4ntxo0y	53	3	had	have	VBD
cord-293701-u4ntxo0y	53	4	shown	show	VBN
cord-293701-u4ntxo0y	53	5	that	that	IN
cord-293701-u4ntxo0y	53	6	FI	FI	NNP
cord-293701-u4ntxo0y	53	7	-	-	HYPH
cord-293701-u4ntxo0y	53	8	RSV	RSV	NNP
cord-293701-u4ntxo0y	53	9	induced	induce	VBD
cord-293701-u4ntxo0y	53	10	a	a	DT
cord-293701-u4ntxo0y	53	11	predominant	predominant	JJ
cord-293701-u4ntxo0y	53	12	T	t	NN
cord-293701-u4ntxo0y	53	13	H	h	NN
cord-293701-u4ntxo0y	53	14	2	2	CD
cord-293701-u4ntxo0y	53	15	cell	cell	NN
cord-293701-u4ntxo0y	53	16	-	-	HYPH
cord-293701-u4ntxo0y	53	17	like	like	JJ
cord-293701-u4ntxo0y	53	18	cytokine	cytokine	NN
cord-293701-u4ntxo0y	53	19	profile	profile	NN
cord-293701-u4ntxo0y	53	20	,	,	,
cord-293701-u4ntxo0y	53	21	such	such	JJ
cord-293701-u4ntxo0y	53	22	as	as	IN
cord-293701-u4ntxo0y	53	23	interleukin-5	interleukin-5	NNP
cord-293701-u4ntxo0y	54	1	(	(	-LRB-
cord-293701-u4ntxo0y	54	2	IL-5	IL-5	NNP
cord-293701-u4ntxo0y	54	3	)	)	-RRB-
cord-293701-u4ntxo0y	54	4	and	and	CC
cord-293701-u4ntxo0y	54	5	IL-13	IL-13	NNP
cord-293701-u4ntxo0y	54	6	,	,	,
cord-293701-u4ntxo0y	54	7	whereas	whereas	IN
cord-293701-u4ntxo0y	54	8	live	live	JJ
cord-293701-u4ntxo0y	54	9	RSV	RSV	NNP
cord-293701-u4ntxo0y	54	10	,	,	,
cord-293701-u4ntxo0y	54	11	which	which	WDT
cord-293701-u4ntxo0y	54	12	did	do	VBD
cord-293701-u4ntxo0y	54	13	not	not	RB
cord-293701-u4ntxo0y	54	14	cause	cause	VB
cord-293701-u4ntxo0y	54	15	ERD	ERD	NNP
cord-293701-u4ntxo0y	54	16	,	,	,
cord-293701-u4ntxo0y	54	17	induced	induce	VBD
cord-293701-u4ntxo0y	54	18	a	a	DT
cord-293701-u4ntxo0y	54	19	predominant	predominant	JJ
cord-293701-u4ntxo0y	54	20	type	type	NN
cord-293701-u4ntxo0y	54	21	1	1	CD
cord-293701-u4ntxo0y	54	22	T	t	NN
cord-293701-u4ntxo0y	54	23	helper	helper	NN
cord-293701-u4ntxo0y	54	24	cell	cell	NN
cord-293701-u4ntxo0y	54	25	(	(	-LRB-
cord-293701-u4ntxo0y	54	26	T	T	NNP
cord-293701-u4ntxo0y	54	27	H	h	NN
cord-293701-u4ntxo0y	54	28	1	1	CD
cord-293701-u4ntxo0y	54	29	cell)-like	cell)-like	NN
cord-293701-u4ntxo0y	54	30	cytokine	cytokine	NN
cord-293701-u4ntxo0y	54	31	profile	profile	NN
cord-293701-u4ntxo0y	54	32	,	,	,
cord-293701-u4ntxo0y	54	33	such	such	JJ
cord-293701-u4ntxo0y	54	34	as	as	IN
cord-293701-u4ntxo0y	54	35	IL-10	IL-10	NNP
cord-293701-u4ntxo0y	54	36	(	(	-LRB-
cord-293701-u4ntxo0y	54	37	refs	ref	NNS
cord-293701-u4ntxo0y	54	38	27,41	27,41	CD
cord-293701-u4ntxo0y	54	39	)	)	-RRB-
cord-293701-u4ntxo0y	54	40	.	.	.
cord-293701-u4ntxo0y	55	1	Furthermore	furthermore	RB
cord-293701-u4ntxo0y	55	2	,	,	,
cord-293701-u4ntxo0y	55	3	some	some	DT
cord-293701-u4ntxo0y	55	4	live	live	VBP
cord-293701-u4ntxo0y	55	5	attenuated	attenuated	JJ
cord-293701-u4ntxo0y	55	6	RSV	RSV	NNP
cord-293701-u4ntxo0y	55	7	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	55	8	and	and	CC
cord-293701-u4ntxo0y	55	9	some	some	DT
cord-293701-u4ntxo0y	55	10	RSV	RSV	NNP
cord-293701-u4ntxo0y	55	11	antigens	antigen	NNS
cord-293701-u4ntxo0y	55	12	expressed	express	VBN
cord-293701-u4ntxo0y	55	13	on	on	IN
cord-293701-u4ntxo0y	55	14	viral	viral	JJ
cord-293701-u4ntxo0y	55	15	or	or	CC
cord-293701-u4ntxo0y	55	16	DNA	dna	NN
cord-293701-u4ntxo0y	55	17	vectors	vector	NNS
cord-293701-u4ntxo0y	55	18	did	do	VBD
cord-293701-u4ntxo0y	55	19	not	not	RB
cord-293701-u4ntxo0y	55	20	induce	induce	VB
cord-293701-u4ntxo0y	55	21	,	,	,
cord-293701-u4ntxo0y	55	22	or	or	CC
cord-293701-u4ntxo0y	55	23	only	only	RB
cord-293701-u4ntxo0y	55	24	slightly	slightly	RB
cord-293701-u4ntxo0y	55	25	induced	induce	VBN
cord-293701-u4ntxo0y	55	26	,	,	,
cord-293701-u4ntxo0y	55	27	ERD	ERD	NNP
cord-293701-u4ntxo0y	55	28	in	in	IN
cord-293701-u4ntxo0y	55	29	humans	human	NNS
cord-293701-u4ntxo0y	55	30	[	[	-LRB-
cord-293701-u4ntxo0y	55	31	42	42	CD
cord-293701-u4ntxo0y	55	32	]	]	-RRB-
cord-293701-u4ntxo0y	55	33	[	[	-LRB-
cord-293701-u4ntxo0y	55	34	43	43	CD
cord-293701-u4ntxo0y	55	35	]	]	-RRB-
cord-293701-u4ntxo0y	55	36	[	[	-LRB-
cord-293701-u4ntxo0y	55	37	44	44	CD
cord-293701-u4ntxo0y	55	38	]	]	-RRB-
cord-293701-u4ntxo0y	55	39	.	.	.
cord-293701-u4ntxo0y	56	1	One	one	CD
cord-293701-u4ntxo0y	56	2	of	of	IN
cord-293701-u4ntxo0y	56	3	the	the	DT
cord-293701-u4ntxo0y	56	4	reasons	reason	NNS
cord-293701-u4ntxo0y	56	5	why	why	WRB
cord-293701-u4ntxo0y	56	6	only	only	RB
cord-293701-u4ntxo0y	56	7	certain	certain	JJ
cord-293701-u4ntxo0y	56	8	antigens	antigen	NNS
cord-293701-u4ntxo0y	56	9	induce	induce	VBP
cord-293701-u4ntxo0y	56	10	ERD	ERD	NNP
cord-293701-u4ntxo0y	56	11	may	may	MD
cord-293701-u4ntxo0y	56	12	be	be	VB
cord-293701-u4ntxo0y	56	13	that	that	IN
cord-293701-u4ntxo0y	56	14	the	the	DT
cord-293701-u4ntxo0y	56	15	surface	surface	NN
cord-293701-u4ntxo0y	56	16	glycoprotein	glycoprotein	NN
cord-293701-u4ntxo0y	56	17	of	of	IN
cord-293701-u4ntxo0y	56	18	RSV	RSV	NNP
cord-293701-u4ntxo0y	56	19	displays	display	VBZ
cord-293701-u4ntxo0y	56	20	diverse	diverse	JJ
cord-293701-u4ntxo0y	56	21	structures	structure	NNS
cord-293701-u4ntxo0y	56	22	,	,	,
cord-293701-u4ntxo0y	56	23	thus	thus	RB
cord-293701-u4ntxo0y	56	24	inducing	induce	VBG
cord-293701-u4ntxo0y	56	25	different	different	JJ
cord-293701-u4ntxo0y	56	26	immune	immune	JJ
cord-293701-u4ntxo0y	56	27	responses	response	NNS
cord-293701-u4ntxo0y	56	28	[	[	-LRB-
cord-293701-u4ntxo0y	56	29	45	45	CD
cord-293701-u4ntxo0y	56	30	]	]	-RRB-
cord-293701-u4ntxo0y	56	31	[	[	-LRB-
cord-293701-u4ntxo0y	56	32	46	46	CD
cord-293701-u4ntxo0y	56	33	]	]	-RRB-
cord-293701-u4ntxo0y	56	34	[	[	-LRB-
cord-293701-u4ntxo0y	56	35	47	47	CD
cord-293701-u4ntxo0y	56	36	]	]	-RRB-
cord-293701-u4ntxo0y	56	37	.	.	.
cord-293701-u4ntxo0y	57	1	Indeed	indeed	RB
cord-293701-u4ntxo0y	57	2	,	,	,
cord-293701-u4ntxo0y	57	3	several	several	JJ
cord-293701-u4ntxo0y	57	4	studies	study	NNS
cord-293701-u4ntxo0y	57	5	showed	show	VBD
cord-293701-u4ntxo0y	57	6	that	that	IN
cord-293701-u4ntxo0y	57	7	exposed	expose	VBN
cord-293701-u4ntxo0y	57	8	antigenic	antigenic	JJ
cord-293701-u4ntxo0y	57	9	sites	site	NNS
cord-293701-u4ntxo0y	57	10	differed	differ	VBD
cord-293701-u4ntxo0y	57	11	between	between	IN
cord-293701-u4ntxo0y	57	12	prefusion	prefusion	NN
cord-293701-u4ntxo0y	57	13	and	and	CC
cord-293701-u4ntxo0y	57	14	postfusion	postfusion	NN
cord-293701-u4ntxo0y	57	15	surface	surface	NN
cord-293701-u4ntxo0y	57	16	proteins	protein	NNS
cord-293701-u4ntxo0y	57	17	and	and	CC
cord-293701-u4ntxo0y	57	18	that	that	IN
cord-293701-u4ntxo0y	57	19	even	even	RB
cord-293701-u4ntxo0y	57	20	antibodies	antibody	NNS
cord-293701-u4ntxo0y	57	21	targeting	target	VBG
cord-293701-u4ntxo0y	57	22	a	a	DT
cord-293701-u4ntxo0y	57	23	shared	share	VBN
cord-293701-u4ntxo0y	57	24	site	site	NN
cord-293701-u4ntxo0y	57	25	might	may	MD
cord-293701-u4ntxo0y	57	26	not	not	RB
cord-293701-u4ntxo0y	57	27	bind	bind	VB
cord-293701-u4ntxo0y	57	28	equally	equally	RB
cord-293701-u4ntxo0y	57	29	to	to	IN
cord-293701-u4ntxo0y	57	30	both	both	DT
cord-293701-u4ntxo0y	57	31	conformations	conformation	NNS
cord-293701-u4ntxo0y	57	32	48	48	CD
cord-293701-u4ntxo0y	57	33	.	.	.
cord-293701-u4ntxo0y	58	1	Notably	notably	RB
cord-293701-u4ntxo0y	58	2	,	,	,
cord-293701-u4ntxo0y	58	3	another	another	DT
cord-293701-u4ntxo0y	58	4	study	study	NN
cord-293701-u4ntxo0y	58	5	reported	report	VBD
cord-293701-u4ntxo0y	58	6	that	that	IN
cord-293701-u4ntxo0y	58	7	both	both	DT
cord-293701-u4ntxo0y	58	8	postfusion	postfusion	NN
cord-293701-u4ntxo0y	58	9	and	and	CC
cord-293701-u4ntxo0y	58	10	prefusion	prefusion	NN
cord-293701-u4ntxo0y	58	11	F	F	NNP
cord-293701-u4ntxo0y	58	12	proteins	protein	NNS
cord-293701-u4ntxo0y	58	13	protected	protect	VBD
cord-293701-u4ntxo0y	58	14	vaccinated	vaccinated	JJ
cord-293701-u4ntxo0y	58	15	cotton	cotton	NN
cord-293701-u4ntxo0y	58	16	rats	rat	NNS
cord-293701-u4ntxo0y	58	17	as	as	RB
cord-293701-u4ntxo0y	58	18	long	long	RB
cord-293701-u4ntxo0y	58	19	as	as	IN
cord-293701-u4ntxo0y	58	20	the	the	DT
cord-293701-u4ntxo0y	58	21	antigen	antigen	NN
cord-293701-u4ntxo0y	58	22	concentration	concentration	NN
cord-293701-u4ntxo0y	58	23	was	be	VBD
cord-293701-u4ntxo0y	58	24	high	high	JJ
cord-293701-u4ntxo0y	58	25	and	and	CC
cord-293701-u4ntxo0y	58	26	the	the	DT
cord-293701-u4ntxo0y	58	27	vaccine	vaccine	NN
cord-293701-u4ntxo0y	58	28	contained	contain	VBD
cord-293701-u4ntxo0y	58	29	a	a	DT
cord-293701-u4ntxo0y	58	30	T	t	NN
cord-293701-u4ntxo0y	58	31	H	h	NN
cord-293701-u4ntxo0y	58	32	1	1	CD
cord-293701-u4ntxo0y	58	33	cell	cell	NN
cord-293701-u4ntxo0y	58	34	-	-	HYPH
cord-293701-u4ntxo0y	58	35	biasing	bias	VBG
cord-293701-u4ntxo0y	58	36	adjuvant	adjuvant	NN
cord-293701-u4ntxo0y	58	37	49	49	CD
cord-293701-u4ntxo0y	58	38	.	.	.
cord-293701-u4ntxo0y	59	1	Aside	aside	RB
cord-293701-u4ntxo0y	59	2	from	from	IN
cord-293701-u4ntxo0y	59	3	the	the	DT
cord-293701-u4ntxo0y	59	4	T	t	NN
cord-293701-u4ntxo0y	59	5	H	h	NN
cord-293701-u4ntxo0y	59	6	2	2	CD
cord-293701-u4ntxo0y	59	7	cell	cell	NN
cord-293701-u4ntxo0y	59	8	-	-	HYPH
cord-293701-u4ntxo0y	59	9	skewed	skewed	JJ
cord-293701-u4ntxo0y	59	10	immune	immune	JJ
cord-293701-u4ntxo0y	59	11	response	response	NN
cord-293701-u4ntxo0y	59	12	,	,	,
cord-293701-u4ntxo0y	59	13	antibody	antibody	NN
cord-293701-u4ntxo0y	59	14	-	-	HYPH
cord-293701-u4ntxo0y	59	15	mediated	mediate	VBN
cord-293701-u4ntxo0y	59	16	effects	effect	NNS
cord-293701-u4ntxo0y	59	17	can	can	MD
cord-293701-u4ntxo0y	59	18	also	also	RB
cord-293701-u4ntxo0y	59	19	contribute	contribute	VB
cord-293701-u4ntxo0y	59	20	to	to	IN
cord-293701-u4ntxo0y	59	21	ERD	ERD	NNP
cord-293701-u4ntxo0y	59	22	.	.	.
cord-293701-u4ntxo0y	60	1	The	the	DT
cord-293701-u4ntxo0y	60	2	non	non	JJ
cord-293701-u4ntxo0y	60	3	-	-	JJ
cord-293701-u4ntxo0y	60	4	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	60	5	induced	induce	VBN
cord-293701-u4ntxo0y	60	6	by	by	IN
cord-293701-u4ntxo0y	60	7	FI	FI	NNP
cord-293701-u4ntxo0y	60	8	-	-	HYPH
cord-293701-u4ntxo0y	60	9	RSV	RSV	NNP
cord-293701-u4ntxo0y	60	10	bound	bind	VBD
cord-293701-u4ntxo0y	60	11	antigen	antigen	NN
cord-293701-u4ntxo0y	60	12	,	,	,
cord-293701-u4ntxo0y	60	13	and	and	CC
cord-293701-u4ntxo0y	60	14	the	the	DT
cord-293701-u4ntxo0y	60	15	antibody	antibody	NN
cord-293701-u4ntxo0y	60	16	-	-	HYPH
cord-293701-u4ntxo0y	60	17	antigen	antigen	NN
cord-293701-u4ntxo0y	60	18	complexes	complex	NNS
cord-293701-u4ntxo0y	60	19	then	then	RB
cord-293701-u4ntxo0y	60	20	stimulated	stimulate	VBD
cord-293701-u4ntxo0y	60	21	the	the	DT
cord-293701-u4ntxo0y	60	22	complement	complement	NN
cord-293701-u4ntxo0y	60	23	pathway	pathway	NN
cord-293701-u4ntxo0y	60	24	,	,	,
cord-293701-u4ntxo0y	60	25	thus	thus	RB
cord-293701-u4ntxo0y	60	26	further	further	RB
cord-293701-u4ntxo0y	60	27	strengthening	strengthen	VBG
cord-293701-u4ntxo0y	60	28	the	the	DT
cord-293701-u4ntxo0y	60	29	inflammatory	inflammatory	JJ
cord-293701-u4ntxo0y	60	30	responses	response	NNS
cord-293701-u4ntxo0y	60	31	50	50	CD
cord-293701-u4ntxo0y	60	32	.	.	.
cord-293701-u4ntxo0y	61	1	In	in	IN
cord-293701-u4ntxo0y	61	2	2019	2019	CD
cord-293701-u4ntxo0y	61	3	,	,	,
cord-293701-u4ntxo0y	61	4	an	an	DT
cord-293701-u4ntxo0y	61	5	RSV	RSV	NNP
cord-293701-u4ntxo0y	61	6	vaccine	vaccine	NN
cord-293701-u4ntxo0y	61	7	based	base	VBN
cord-293701-u4ntxo0y	61	8	on	on	IN
cord-293701-u4ntxo0y	61	9	an	an	DT
cord-293701-u4ntxo0y	61	10	adenovirus	adenovirus	NN
cord-293701-u4ntxo0y	61	11	vector	vector	NN
cord-293701-u4ntxo0y	61	12	expressing	express	VBG
cord-293701-u4ntxo0y	61	13	RSV	RSV	NNP
cord-293701-u4ntxo0y	61	14	F	F	NNP
cord-293701-u4ntxo0y	61	15	protein	protein	NN
cord-293701-u4ntxo0y	61	16	stabilized	stabilize	VBD
cord-293701-u4ntxo0y	61	17	in	in	IN
cord-293701-u4ntxo0y	61	18	its	-PRON-	PRP$
cord-293701-u4ntxo0y	61	19	prefusion	prefusion	NN
cord-293701-u4ntxo0y	61	20	conformation	conformation	NN
cord-293701-u4ntxo0y	61	21	(	(	-LRB-
cord-293701-u4ntxo0y	61	22	Ad26.RSV.preF	Ad26.RSV.preF	NNP
cord-293701-u4ntxo0y	61	23	)	)	-RRB-
cord-293701-u4ntxo0y	61	24	passed	pass	VBD
cord-293701-u4ntxo0y	61	25	the	the	DT
cord-293701-u4ntxo0y	61	26	FDA	FDA	NNP
cord-293701-u4ntxo0y	61	27	Breakthrough	Breakthrough	NNP
cord-293701-u4ntxo0y	61	28	Therapy	Therapy	NNP
cord-293701-u4ntxo0y	61	29	Designation	Designation	NNP
cord-293701-u4ntxo0y	61	30	programme	programme	NN
cord-293701-u4ntxo0y	61	31	for	for	IN
cord-293701-u4ntxo0y	61	32	the	the	DT
cord-293701-u4ntxo0y	61	33	prevention	prevention	NN
cord-293701-u4ntxo0y	61	34	of	of	IN
cord-293701-u4ntxo0y	61	35	RSV	RSV	NNP
cord-293701-u4ntxo0y	61	36	in	in	IN
cord-293701-u4ntxo0y	61	37	older	old	JJR
cord-293701-u4ntxo0y	61	38	adults	adult	NNS
cord-293701-u4ntxo0y	61	39	.	.	.
cord-293701-u4ntxo0y	62	1	Ad26.RSV.preF	Ad26.RSV.preF	NNP
cord-293701-u4ntxo0y	62	2	induced	induce	VBD
cord-293701-u4ntxo0y	62	3	a	a	DT
cord-293701-u4ntxo0y	62	4	high	high	JJ
cord-293701-u4ntxo0y	62	5	titre	titre	NN
cord-293701-u4ntxo0y	62	6	of	of	IN
cord-293701-u4ntxo0y	62	7	NAb	NAb	NNS
cord-293701-u4ntxo0y	62	8	and	and	CC
cord-293701-u4ntxo0y	62	9	long	long	RB
cord-293701-u4ntxo0y	62	10	-	-	HYPH
cord-293701-u4ntxo0y	62	11	lasting	last	VBG
cord-293701-u4ntxo0y	62	12	T	t	NN
cord-293701-u4ntxo0y	62	13	H	h	NN
cord-293701-u4ntxo0y	62	14	1	1	CD
cord-293701-u4ntxo0y	62	15	cell	cell	NN
cord-293701-u4ntxo0y	62	16	-	-	HYPH
cord-293701-u4ntxo0y	62	17	biased	bias	VBN
cord-293701-u4ntxo0y	62	18	immunity	immunity	NN
cord-293701-u4ntxo0y	62	19	characterized	characterize	VBN
cord-293701-u4ntxo0y	62	20	by	by	IN
cord-293701-u4ntxo0y	62	21	a	a	DT
cord-293701-u4ntxo0y	62	22	high	high	JJ
cord-293701-u4ntxo0y	62	23	ratio	ratio	NN
cord-293701-u4ntxo0y	62	24	of	of	IN
cord-293701-u4ntxo0y	62	25	interferon	interferon	NN
cord-293701-u4ntxo0y	62	26	-	-	HYPH
cord-293701-u4ntxo0y	62	27	γ	γ	NN
cord-293701-u4ntxo0y	62	28	(	(	-LRB-
cord-293701-u4ntxo0y	62	29	T	T	NNP
cord-293701-u4ntxo0y	62	30	H	H	NNP
cord-293701-u4ntxo0y	62	31	1-type	1-type	CD
cord-293701-u4ntxo0y	62	32	cytokine	cytokine	NN
cord-293701-u4ntxo0y	62	33	)	)	-RRB-
cord-293701-u4ntxo0y	62	34	and	and	CC
cord-293701-u4ntxo0y	62	35	T	T	NNP
cord-293701-u4ntxo0y	62	36	H	H	NNP
cord-293701-u4ntxo0y	62	37	2-type	2-type	CD
cord-293701-u4ntxo0y	62	38	cytokines	cytokine	NNS
cord-293701-u4ntxo0y	62	39	(	(	-LRB-
cord-293701-u4ntxo0y	62	40	IL-4	IL-4	NNP
cord-293701-u4ntxo0y	62	41	,	,	,
cord-293701-u4ntxo0y	62	42	IL-5	IL-5	NNP
cord-293701-u4ntxo0y	62	43	or	or	CC
cord-293701-u4ntxo0y	62	44	IL-10	IL-10	NNP
cord-293701-u4ntxo0y	62	45	)	)	-RRB-
cord-293701-u4ntxo0y	62	46	in	in	IN
cord-293701-u4ntxo0y	62	47	adult	adult	NN
cord-293701-u4ntxo0y	62	48	and	and	CC
cord-293701-u4ntxo0y	62	49	neonatal	neonatal	JJ
cord-293701-u4ntxo0y	62	50	mice	mouse	NNS
cord-293701-u4ntxo0y	62	51	51	51	CD
cord-293701-u4ntxo0y	62	52	.	.	.
cord-293701-u4ntxo0y	63	1	However	however	RB
cord-293701-u4ntxo0y	63	2	,	,	,
cord-293701-u4ntxo0y	63	3	the	the	DT
cord-293701-u4ntxo0y	63	4	clinical	clinical	JJ
cord-293701-u4ntxo0y	63	5	trial	trial	NN
cord-293701-u4ntxo0y	63	6	of	of	IN
cord-293701-u4ntxo0y	63	7	Ad26.RSV	Ad26.RSV	NNP
cord-293701-u4ntxo0y	63	8	.	.	.
cord-293701-u4ntxo0y	64	1	preF	preF	NNP
cord-293701-u4ntxo0y	64	2	was	be	VBD
cord-293701-u4ntxo0y	64	3	done	do	VBN
cord-293701-u4ntxo0y	64	4	only	only	RB
cord-293701-u4ntxo0y	64	5	in	in	IN
cord-293701-u4ntxo0y	64	6	adults	adult	NNS
cord-293701-u4ntxo0y	64	7	aged	age	VBN
cord-293701-u4ntxo0y	64	8	60	60	CD
cord-293701-u4ntxo0y	64	9	years	year	NNS
cord-293701-u4ntxo0y	64	10	or	or	CC
cord-293701-u4ntxo0y	64	11	older	old	JJR
cord-293701-u4ntxo0y	64	12	52	52	CD
cord-293701-u4ntxo0y	64	13	;	;	:
cord-293701-u4ntxo0y	64	14	thus	thus	RB
cord-293701-u4ntxo0y	64	15	,	,	,
cord-293701-u4ntxo0y	64	16	an	an	DT
cord-293701-u4ntxo0y	64	17	RSV	RSV	NNP
cord-293701-u4ntxo0y	64	18	vaccine	vaccine	NN
cord-293701-u4ntxo0y	64	19	for	for	IN
cord-293701-u4ntxo0y	64	20	infants	infant	NNS
cord-293701-u4ntxo0y	64	21	remains	remain	VBZ
cord-293701-u4ntxo0y	64	22	elusive	elusive	JJ
cord-293701-u4ntxo0y	64	23	.	.	.
cord-293701-u4ntxo0y	65	1	Thus	thus	RB
cord-293701-u4ntxo0y	65	2	,	,	,
cord-293701-u4ntxo0y	65	3	throughout	throughout	IN
cord-293701-u4ntxo0y	65	4	the	the	DT
cord-293701-u4ntxo0y	65	5	50-year	50-year	JJ
cord-293701-u4ntxo0y	65	6	history	history	NN
cord-293701-u4ntxo0y	65	7	of	of	IN
cord-293701-u4ntxo0y	65	8	exploring	explore	VBG
cord-293701-u4ntxo0y	65	9	RSV	RSV	NNP
cord-293701-u4ntxo0y	65	10	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	65	11	,	,	,
cord-293701-u4ntxo0y	65	12	we	-PRON-	PRP
cord-293701-u4ntxo0y	65	13	have	have	VBP
cord-293701-u4ntxo0y	65	14	learnt	learn	VBN
cord-293701-u4ntxo0y	65	15	the	the	DT
cord-293701-u4ntxo0y	65	16	absolute	absolute	JJ
cord-293701-u4ntxo0y	65	17	necessity	necessity	NN
cord-293701-u4ntxo0y	65	18	of	of	IN
cord-293701-u4ntxo0y	65	19	tracking	track	VBG
cord-293701-u4ntxo0y	65	20	the	the	DT
cord-293701-u4ntxo0y	65	21	comprehensive	comprehensive	JJ
cord-293701-u4ntxo0y	65	22	safety	safety	NN
cord-293701-u4ntxo0y	65	23	of	of	IN
cord-293701-u4ntxo0y	65	24	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	65	25	before	before	IN
cord-293701-u4ntxo0y	65	26	large	large	JJ
cord-293701-u4ntxo0y	65	27	-	-	HYPH
cord-293701-u4ntxo0y	65	28	scale	scale	NN
cord-293701-u4ntxo0y	65	29	application	application	NN
cord-293701-u4ntxo0y	65	30	,	,	,
cord-293701-u4ntxo0y	65	31	no	no	RB
cord-293701-u4ntxo0y	65	32	matter	matter	RB
cord-293701-u4ntxo0y	65	33	the	the	DT
cord-293701-u4ntxo0y	65	34	urgency	urgency	NN
cord-293701-u4ntxo0y	65	35	of	of	IN
cord-293701-u4ntxo0y	65	36	the	the	DT
cord-293701-u4ntxo0y	65	37	moment	moment	NN
cord-293701-u4ntxo0y	65	38	.	.	.
cord-293701-u4ntxo0y	66	1	From	from	IN
cord-293701-u4ntxo0y	66	2	the	the	DT
cord-293701-u4ntxo0y	66	3	RSV	RSV	NNP
cord-293701-u4ntxo0y	66	4	experience	experience	NN
cord-293701-u4ntxo0y	66	5	,	,	,
cord-293701-u4ntxo0y	66	6	we	-PRON-	PRP
cord-293701-u4ntxo0y	66	7	still	still	RB
cord-293701-u4ntxo0y	66	8	do	do	VBP
cord-293701-u4ntxo0y	66	9	not	not	RB
cord-293701-u4ntxo0y	66	10	know	know	VB
cord-293701-u4ntxo0y	66	11	what	what	WP
cord-293701-u4ntxo0y	66	12	features	feature	VBZ
cord-293701-u4ntxo0y	66	13	of	of	IN
cord-293701-u4ntxo0y	66	14	an	an	DT
cord-293701-u4ntxo0y	66	15	antigen	antigen	NN
cord-293701-u4ntxo0y	66	16	will	will	MD
cord-293701-u4ntxo0y	66	17	create	create	VB
cord-293701-u4ntxo0y	66	18	disease	disease	NN
cord-293701-u4ntxo0y	66	19	exacerbation	exacerbation	NN
cord-293701-u4ntxo0y	66	20	,	,	,
cord-293701-u4ntxo0y	66	21	although	although	IN
cord-293701-u4ntxo0y	66	22	we	-PRON-	PRP
cord-293701-u4ntxo0y	66	23	do	do	VBP
cord-293701-u4ntxo0y	66	24	know	know	VB
cord-293701-u4ntxo0y	66	25	that	that	IN
cord-293701-u4ntxo0y	66	26	antigen	antigen	NN
cord-293701-u4ntxo0y	66	27	conformation	conformation	NN
cord-293701-u4ntxo0y	66	28	and	and	CC
cord-293701-u4ntxo0y	66	29	prefusion	prefusion	NN
cord-293701-u4ntxo0y	66	30	versus	versus	IN
cord-293701-u4ntxo0y	66	31	fusion	fusion	NN
cord-293701-u4ntxo0y	66	32	states	state	NNS
cord-293701-u4ntxo0y	66	33	are	be	VBP
cord-293701-u4ntxo0y	66	34	important	important	JJ
cord-293701-u4ntxo0y	66	35	.	.	.
cord-293701-u4ntxo0y	67	1	We	-PRON-	PRP
cord-293701-u4ntxo0y	67	2	have	have	VBP
cord-293701-u4ntxo0y	67	3	also	also	RB
cord-293701-u4ntxo0y	67	4	learnt	learn	VBN
cord-293701-u4ntxo0y	67	5	that	that	IN
cord-293701-u4ntxo0y	67	6	a	a	DT
cord-293701-u4ntxo0y	67	7	T	t	NN
cord-293701-u4ntxo0y	67	8	H	h	NN
cord-293701-u4ntxo0y	67	9	2	2	CD
cord-293701-u4ntxo0y	67	10	cell	cell	NN
cord-293701-u4ntxo0y	67	11	-	-	HYPH
cord-293701-u4ntxo0y	67	12	biased	bias	VBN
cord-293701-u4ntxo0y	67	13	immune	immune	JJ
cord-293701-u4ntxo0y	67	14	response	response	NN
cord-293701-u4ntxo0y	67	15	is	be	VBZ
cord-293701-u4ntxo0y	67	16	harmful	harmful	JJ
cord-293701-u4ntxo0y	67	17	.	.	.
cord-293701-u4ntxo0y	68	1	For	for	IN
cord-293701-u4ntxo0y	68	2	example	example	NN
cord-293701-u4ntxo0y	68	3	,	,	,
cord-293701-u4ntxo0y	68	4	an	an	DT
cord-293701-u4ntxo0y	68	5	antigen	antigen	NN
cord-293701-u4ntxo0y	68	6	-	-	HYPH
cord-293701-u4ntxo0y	68	7	induced	induce	VBN
cord-293701-u4ntxo0y	68	8	T	t	NN
cord-293701-u4ntxo0y	68	9	H	h	NN
cord-293701-u4ntxo0y	68	10	2	2	CD
cord-293701-u4ntxo0y	68	11	cell	cell	NN
cord-293701-u4ntxo0y	68	12	-	-	HYPH
cord-293701-u4ntxo0y	68	13	like	like	JJ
cord-293701-u4ntxo0y	68	14	cytokine	cytokine	NN
cord-293701-u4ntxo0y	68	15	profile	profile	NN
cord-293701-u4ntxo0y	68	16	,	,	,
cord-293701-u4ntxo0y	68	17	such	such	JJ
cord-293701-u4ntxo0y	68	18	as	as	IN
cord-293701-u4ntxo0y	68	19	IL-5	IL-5	NNP
cord-293701-u4ntxo0y	68	20	and	and	CC
cord-293701-u4ntxo0y	68	21	IL-13	IL-13	NNP
cord-293701-u4ntxo0y	68	22	,	,	,
cord-293701-u4ntxo0y	68	23	could	could	MD
cord-293701-u4ntxo0y	68	24	activate	activate	VB
cord-293701-u4ntxo0y	68	25	CD4	CD4	NNP
cord-293701-u4ntxo0y	68	26	+	+	CC
cord-293701-u4ntxo0y	68	27	T	t	NN
cord-293701-u4ntxo0y	68	28	cells	cell	NNS
cord-293701-u4ntxo0y	68	29	but	but	CC
cord-293701-u4ntxo0y	68	30	poorly	poorly	RB
cord-293701-u4ntxo0y	68	31	stimulate	stimulate	VBP
cord-293701-u4ntxo0y	68	32	natural	natural	JJ
cord-293701-u4ntxo0y	68	33	killer	killer	NN
cord-293701-u4ntxo0y	68	34	cells	cell	NNS
cord-293701-u4ntxo0y	68	35	and	and	CC
cord-293701-u4ntxo0y	68	36	CD8	CD8	NNP
cord-293701-u4ntxo0y	68	37	+	+	CC
cord-293701-u4ntxo0y	68	38	T	T	NNP
cord-293701-u4ntxo0y	68	39	cells	cell	NNS
cord-293701-u4ntxo0y	68	40	in	in	IN
cord-293701-u4ntxo0y	68	41	an	an	DT
cord-293701-u4ntxo0y	68	42	animal	animal	NN
cord-293701-u4ntxo0y	68	43	model	model	NN
cord-293701-u4ntxo0y	68	44	or	or	CC
cord-293701-u4ntxo0y	68	45	human	human	NN
cord-293701-u4ntxo0y	68	46	.	.	.
cord-293701-u4ntxo0y	69	1	Such	such	JJ
cord-293701-u4ntxo0y	69	2	a	a	DT
cord-293701-u4ntxo0y	69	3	T	t	NN
cord-293701-u4ntxo0y	69	4	H	h	NN
cord-293701-u4ntxo0y	69	5	2	2	CD
cord-293701-u4ntxo0y	69	6	cell	cell	NN
cord-293701-u4ntxo0y	69	7	-	-	HYPH
cord-293701-u4ntxo0y	69	8	biased	bias	VBN
cord-293701-u4ntxo0y	69	9	immune	immune	JJ
cord-293701-u4ntxo0y	69	10	response	response	NN
cord-293701-u4ntxo0y	69	11	might	may	MD
cord-293701-u4ntxo0y	69	12	result	result	VB
cord-293701-u4ntxo0y	69	13	in	in	IN
cord-293701-u4ntxo0y	69	14	VADE	VADE	NNP
cord-293701-u4ntxo0y	69	15	under	under	IN
cord-293701-u4ntxo0y	69	16	viral	viral	JJ
cord-293701-u4ntxo0y	69	17	challenge	challenge	NN
cord-293701-u4ntxo0y	69	18	.	.	.
cord-293701-u4ntxo0y	70	1	Furthermore	furthermore	RB
cord-293701-u4ntxo0y	70	2	,	,	,
cord-293701-u4ntxo0y	70	3	we	-PRON-	PRP
cord-293701-u4ntxo0y	70	4	have	have	VBP
cord-293701-u4ntxo0y	70	5	learnt	learn	VBN
cord-293701-u4ntxo0y	70	6	that	that	IN
cord-293701-u4ntxo0y	70	7	the	the	DT
cord-293701-u4ntxo0y	70	8	induction	induction	NN
cord-293701-u4ntxo0y	70	9	of	of	IN
cord-293701-u4ntxo0y	70	10	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	70	11	over	over	IN
cord-293701-u4ntxo0y	70	12	binding	bind	VBG
cord-293701-u4ntxo0y	70	13	antibodies	antibody	NNS
cord-293701-u4ntxo0y	70	14	is	be	VBZ
cord-293701-u4ntxo0y	70	15	crucial	crucial	JJ
cord-293701-u4ntxo0y	70	16	.	.	.
cord-293701-u4ntxo0y	71	1	Similarly	similarly	RB
cord-293701-u4ntxo0y	71	2	to	to	IN
cord-293701-u4ntxo0y	71	3	RSV	RSV	NNP
cord-293701-u4ntxo0y	71	4	,	,	,
cord-293701-u4ntxo0y	71	5	the	the	DT
cord-293701-u4ntxo0y	71	6	development	development	NN
cord-293701-u4ntxo0y	71	7	of	of	IN
cord-293701-u4ntxo0y	71	8	dengue	dengue	NN
cord-293701-u4ntxo0y	71	9	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	71	10	started	start	VBD
cord-293701-u4ntxo0y	71	11	with	with	IN
cord-293701-u4ntxo0y	71	12	an	an	DT
cord-293701-u4ntxo0y	71	13	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	71	14	virus	virus	NN
cord-293701-u4ntxo0y	71	15	-	-	HYPH
cord-293701-u4ntxo0y	71	16	based	base	VBN
cord-293701-u4ntxo0y	71	17	vaccine	vaccine	NN
cord-293701-u4ntxo0y	71	18	.	.	.
cord-293701-u4ntxo0y	72	1	In	in	IN
cord-293701-u4ntxo0y	72	2	the	the	DT
cord-293701-u4ntxo0y	72	3	1920s	1920	NNS
cord-293701-u4ntxo0y	72	4	,	,	,
cord-293701-u4ntxo0y	72	5	Blanc	Blanc	NNP
cord-293701-u4ntxo0y	72	6	Box	Box	NNP
cord-293701-u4ntxo0y	72	7	1	1	CD
cord-293701-u4ntxo0y	72	8	|	|	CD
cord-293701-u4ntxo0y	72	9	Key	key	JJ
cord-293701-u4ntxo0y	72	10	terms	term	NNS
cord-293701-u4ntxo0y	72	11	in	in	IN
cord-293701-u4ntxo0y	72	12	disease	disease	NN
cord-293701-u4ntxo0y	72	13	enhancement	enhancement	NN
cord-293701-u4ntxo0y	72	14	ADE	ADE	NNP
cord-293701-u4ntxo0y	72	15	antibody	antibody	NN
cord-293701-u4ntxo0y	72	16	-	-	HYPH
cord-293701-u4ntxo0y	72	17	dependent	dependent	JJ
cord-293701-u4ntxo0y	72	18	enhancement	enhancement	NN
cord-293701-u4ntxo0y	72	19	(	(	-LRB-
cord-293701-u4ntxo0y	72	20	aDe	aDe	NNS
cord-293701-u4ntxo0y	72	21	)	)	-RRB-
cord-293701-u4ntxo0y	72	22	can	can	MD
cord-293701-u4ntxo0y	72	23	be	be	VB
cord-293701-u4ntxo0y	72	24	mediated	mediate	VBN
cord-293701-u4ntxo0y	72	25	by	by	IN
cord-293701-u4ntxo0y	72	26	antibody	antibody	NN
cord-293701-u4ntxo0y	72	27	Fc	Fc	NNP
cord-293701-u4ntxo0y	72	28	receptor	receptor	NN
cord-293701-u4ntxo0y	72	29	-	-	HYPH
cord-293701-u4ntxo0y	72	30	associated	associate	VBN
cord-293701-u4ntxo0y	72	31	internalization	internalization	NN
cord-293701-u4ntxo0y	72	32	of	of	IN
cord-293701-u4ntxo0y	72	33	a	a	DT
cord-293701-u4ntxo0y	72	34	virus	virus	NN
cord-293701-u4ntxo0y	72	35	,	,	,
cord-293701-u4ntxo0y	72	36	thus	thus	RB
cord-293701-u4ntxo0y	72	37	resulting	result	VBG
cord-293701-u4ntxo0y	72	38	in	in	IN
cord-293701-u4ntxo0y	72	39	more	more	RBR
cord-293701-u4ntxo0y	72	40	extensive	extensive	JJ
cord-293701-u4ntxo0y	72	41	viral	viral	JJ
cord-293701-u4ntxo0y	72	42	replication	replication	NN
cord-293701-u4ntxo0y	72	43	and	and	CC
cord-293701-u4ntxo0y	72	44	cytokine	cytokine	NN
cord-293701-u4ntxo0y	72	45	release	release	NN
cord-293701-u4ntxo0y	72	46	in	in	IN
cord-293701-u4ntxo0y	72	47	the	the	DT
cord-293701-u4ntxo0y	72	48	presence	presence	NN
cord-293701-u4ntxo0y	72	49	of	of	IN
cord-293701-u4ntxo0y	72	50	virus	virus	NN
cord-293701-u4ntxo0y	72	51	-	-	HYPH
cord-293701-u4ntxo0y	72	52	specific	specific	JJ
cord-293701-u4ntxo0y	72	53	antibodies	antibody	NNS
cord-293701-u4ntxo0y	72	54	.	.	.
cord-293701-u4ntxo0y	73	1	aDe	aDe	NNS
cord-293701-u4ntxo0y	73	2	was	be	VBD
cord-293701-u4ntxo0y	73	3	widely	widely	RB
cord-293701-u4ntxo0y	73	4	reported	report	VBN
cord-293701-u4ntxo0y	73	5	in	in	IN
cord-293701-u4ntxo0y	73	6	flavivirus	flavivirus	JJ
cord-293701-u4ntxo0y	73	7	and	and	CC
cord-293701-u4ntxo0y	73	8	other	other	JJ
cord-293701-u4ntxo0y	73	9	viral	viral	JJ
cord-293701-u4ntxo0y	73	10	infections	infection	NNS
cord-293701-u4ntxo0y	73	11	,	,	,
cord-293701-u4ntxo0y	73	12	such	such	JJ
cord-293701-u4ntxo0y	73	13	as	as	IN
cord-293701-u4ntxo0y	73	14	Hiv	Hiv	NNP
cord-293701-u4ntxo0y	73	15	and	and	CC
cord-293701-u4ntxo0y	73	16	influenza	influenza	NN
cord-293701-u4ntxo0y	73	17	virus	virus	NN
cord-293701-u4ntxo0y	73	18	infections	infection	NNS
cord-293701-u4ntxo0y	73	19	.	.	.
cord-293701-u4ntxo0y	74	1	ErD	ErD	NNP
cord-293701-u4ntxo0y	74	2	enhanced	enhance	VBD
cord-293701-u4ntxo0y	74	3	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	74	4	disease	disease	NN
cord-293701-u4ntxo0y	74	5	(	(	-LRB-
cord-293701-u4ntxo0y	74	6	erD	erd	NN
cord-293701-u4ntxo0y	74	7	)	)	-RRB-
cord-293701-u4ntxo0y	74	8	describes	describe	VBZ
cord-293701-u4ntxo0y	74	9	severer	severe	JJR
cord-293701-u4ntxo0y	74	10	clinical	clinical	JJ
cord-293701-u4ntxo0y	74	11	symptoms	symptom	NNS
cord-293701-u4ntxo0y	74	12	after	after	IN
cord-293701-u4ntxo0y	74	13	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	74	14	virus	virus	NN
cord-293701-u4ntxo0y	74	15	infection	infection	NN
cord-293701-u4ntxo0y	74	16	,	,	,
cord-293701-u4ntxo0y	74	17	such	such	JJ
cord-293701-u4ntxo0y	74	18	as	as	IN
cord-293701-u4ntxo0y	74	19	with	with	IN
cord-293701-u4ntxo0y	74	20	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	74	21	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	74	22	virus	virus	NN
cord-293701-u4ntxo0y	74	23	and	and	CC
cord-293701-u4ntxo0y	74	24	influenza	influenza	NN
cord-293701-u4ntxo0y	74	25	virus	virus	NN
cord-293701-u4ntxo0y	74	26	,	,	,
cord-293701-u4ntxo0y	74	27	due	due	IN
cord-293701-u4ntxo0y	74	28	to	to	IN
cord-293701-u4ntxo0y	74	29	previous	previous	JJ
cord-293701-u4ntxo0y	74	30	immune	immune	JJ
cord-293701-u4ntxo0y	74	31	responses	response	NNS
cord-293701-u4ntxo0y	74	32	.	.	.
cord-293701-u4ntxo0y	75	1	erD	erd	PRP$
cord-293701-u4ntxo0y	75	2	usually	usually	RB
cord-293701-u4ntxo0y	75	3	manifests	manifest	VBZ
cord-293701-u4ntxo0y	75	4	itself	-PRON-	PRP
cord-293701-u4ntxo0y	75	5	as	as	IN
cord-293701-u4ntxo0y	75	6	peribronchiolar	peribronchiolar	NN
cord-293701-u4ntxo0y	75	7	monocytic	monocytic	JJ
cord-293701-u4ntxo0y	75	8	infiltration	infiltration	NN
cord-293701-u4ntxo0y	75	9	with	with	IN
cord-293701-u4ntxo0y	75	10	an	an	DT
cord-293701-u4ntxo0y	75	11	excess	excess	NN
cord-293701-u4ntxo0y	75	12	of	of	IN
cord-293701-u4ntxo0y	75	13	eosinophils	eosinophil	NNS
cord-293701-u4ntxo0y	75	14	.	.	.
cord-293701-u4ntxo0y	76	1	erD	erd	EX
cord-293701-u4ntxo0y	76	2	can	can	MD
cord-293701-u4ntxo0y	76	3	happen	happen	VB
cord-293701-u4ntxo0y	76	4	during	during	IN
cord-293701-u4ntxo0y	76	5	homotypic	homotypic	NNP
cord-293701-u4ntxo0y	76	6	or	or	CC
cord-293701-u4ntxo0y	76	7	heterotypic	heterotypic	NNP
cord-293701-u4ntxo0y	76	8	serotype	serotype	NNP
cord-293701-u4ntxo0y	76	9	virus	virus	NN
cord-293701-u4ntxo0y	76	10	infection	infection	NN
cord-293701-u4ntxo0y	76	11	after	after	IN
cord-293701-u4ntxo0y	76	12	vaccination	vaccination	NN
cord-293701-u4ntxo0y	76	13	,	,	,
cord-293701-u4ntxo0y	76	14	natural	natural	JJ
cord-293701-u4ntxo0y	76	15	infection	infection	NN
cord-293701-u4ntxo0y	76	16	or	or	CC
cord-293701-u4ntxo0y	76	17	transfer	transfer	NN
cord-293701-u4ntxo0y	76	18	of	of	IN
cord-293701-u4ntxo0y	76	19	maternal	maternal	JJ
cord-293701-u4ntxo0y	76	20	passive	passive	JJ
cord-293701-u4ntxo0y	76	21	immunity	immunity	NN
cord-293701-u4ntxo0y	76	22	.	.	.
cord-293701-u4ntxo0y	77	1	vaccine	vaccine	NN
cord-293701-u4ntxo0y	77	2	-	-	HYPH
cord-293701-u4ntxo0y	77	3	associated	associate	VBN
cord-293701-u4ntxo0y	77	4	disease	disease	NN
cord-293701-u4ntxo0y	77	5	enhancement	enhancement	NN
cord-293701-u4ntxo0y	77	6	(	(	-LRB-
cord-293701-u4ntxo0y	77	7	vaDe	vade	NN
cord-293701-u4ntxo0y	77	8	)	)	-RRB-
cord-293701-u4ntxo0y	77	9	partially	partially	RB
cord-293701-u4ntxo0y	77	10	overlaps	overlap	VBZ
cord-293701-u4ntxo0y	77	11	with	with	IN
cord-293701-u4ntxo0y	77	12	aDe	aDe	NNS
cord-293701-u4ntxo0y	77	13	and	and	CC
cord-293701-u4ntxo0y	77	14	erD.	erd.	VB
cord-293701-u4ntxo0y	77	15	in	in	IN
cord-293701-u4ntxo0y	77	16	contrast	contrast	NN
cord-293701-u4ntxo0y	77	17	to	to	IN
cord-293701-u4ntxo0y	77	18	erD	erd	NN
cord-293701-u4ntxo0y	77	19	,	,	,
cord-293701-u4ntxo0y	77	20	vaDe	vade	IN
cord-293701-u4ntxo0y	77	21	involves	involve	VBZ
cord-293701-u4ntxo0y	77	22	only	only	RB
cord-293701-u4ntxo0y	77	23	the	the	DT
cord-293701-u4ntxo0y	77	24	vaccine	vaccine	NN
cord-293701-u4ntxo0y	77	25	-	-	HYPH
cord-293701-u4ntxo0y	77	26	associated	associate	VBN
cord-293701-u4ntxo0y	77	27	situation	situation	NN
cord-293701-u4ntxo0y	77	28	,	,	,
cord-293701-u4ntxo0y	77	29	and	and	CC
cord-293701-u4ntxo0y	77	30	,	,	,
cord-293701-u4ntxo0y	77	31	more	more	RBR
cord-293701-u4ntxo0y	77	32	importantly	importantly	RB
cord-293701-u4ntxo0y	77	33	,	,	,
cord-293701-u4ntxo0y	77	34	it	-PRON-	PRP
cord-293701-u4ntxo0y	77	35	is	be	VBZ
cord-293701-u4ntxo0y	77	36	not	not	RB
cord-293701-u4ntxo0y	77	37	limited	limit	VBN
cord-293701-u4ntxo0y	77	38	to	to	IN
cord-293701-u4ntxo0y	77	39	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	77	40	disease	disease	NN
cord-293701-u4ntxo0y	77	41	.	.	.
cord-293701-u4ntxo0y	78	1	For	for	IN
cord-293701-u4ntxo0y	78	2	example	example	NN
cord-293701-u4ntxo0y	78	3	,	,	,
cord-293701-u4ntxo0y	78	4	heterotypic	heterotypic	JJ
cord-293701-u4ntxo0y	78	5	-	-	HYPH
cord-293701-u4ntxo0y	78	6	serotype	serotype	NN
cord-293701-u4ntxo0y	78	7	dengue	dengue	NN
cord-293701-u4ntxo0y	78	8	virus	virus	NN
cord-293701-u4ntxo0y	78	9	infection	infection	NN
cord-293701-u4ntxo0y	78	10	may	may	MD
cord-293701-u4ntxo0y	78	11	cause	cause	VB
cord-293701-u4ntxo0y	78	12	severer	severe	JJR
cord-293701-u4ntxo0y	78	13	dengue	dengue	NN
cord-293701-u4ntxo0y	78	14	haemorrhagic	haemorrhagic	JJ
cord-293701-u4ntxo0y	78	15	fever	fever	NN
cord-293701-u4ntxo0y	78	16	in	in	IN
cord-293701-u4ntxo0y	78	17	vaccinated	vaccinate	VBN
cord-293701-u4ntxo0y	78	18	individuals	individual	NNS
cord-293701-u4ntxo0y	78	19	.	.	.
cord-293701-u4ntxo0y	79	1	this	this	DT
cord-293701-u4ntxo0y	79	2	phenomenon	phenomenon	NN
cord-293701-u4ntxo0y	79	3	is	be	VBZ
cord-293701-u4ntxo0y	79	4	related	relate	VBN
cord-293701-u4ntxo0y	79	5	to	to	IN
cord-293701-u4ntxo0y	79	6	vaDe	vade	NN
cord-293701-u4ntxo0y	79	7	,	,	,
cord-293701-u4ntxo0y	79	8	but	but	CC
cord-293701-u4ntxo0y	79	9	does	do	VBZ
cord-293701-u4ntxo0y	79	10	not	not	RB
cord-293701-u4ntxo0y	79	11	include	include	VB
cord-293701-u4ntxo0y	79	12	erD.	erd.	XX
cord-293701-u4ntxo0y	80	1	vaDe	vade	VBP
cord-293701-u4ntxo0y	80	2	can	can	MD
cord-293701-u4ntxo0y	80	3	be	be	VB
cord-293701-u4ntxo0y	80	4	attributed	attribute	VBN
cord-293701-u4ntxo0y	80	5	to	to	IN
cord-293701-u4ntxo0y	80	6	antibody	antibody	NN
cord-293701-u4ntxo0y	80	7	-	-	HYPH
cord-293701-u4ntxo0y	80	8	dependent	dependent	JJ
cord-293701-u4ntxo0y	80	9	and	and	CC
cord-293701-u4ntxo0y	80	10	type	type	NN
cord-293701-u4ntxo0y	80	11	2	2	CD
cord-293701-u4ntxo0y	80	12	t	t	NN
cord-293701-u4ntxo0y	80	13	helper	helper	NN
cord-293701-u4ntxo0y	80	14	cell	cell	NN
cord-293701-u4ntxo0y	80	15	-	-	HYPH
cord-293701-u4ntxo0y	80	16	dependent	dependent	JJ
cord-293701-u4ntxo0y	80	17	mechanisms	mechanism	NNS
cord-293701-u4ntxo0y	80	18	.	.	.
cord-293701-u4ntxo0y	81	1	www.nature.com/nrmicro	www.nature.com/nrmicro	NNP
cord-293701-u4ntxo0y	81	2	and	and	CC
cord-293701-u4ntxo0y	81	3	Cminopetros	Cminopetros	NNP
cord-293701-u4ntxo0y	81	4	inoculated	inoculate	VBD
cord-293701-u4ntxo0y	81	5	study	study	NN
cord-293701-u4ntxo0y	81	6	participants	participant	NNS
cord-293701-u4ntxo0y	81	7	with	with	IN
cord-293701-u4ntxo0y	81	8	a	a	DT
cord-293701-u4ntxo0y	81	9	bile	bile	NN
cord-293701-u4ntxo0y	81	10	-	-	HYPH
cord-293701-u4ntxo0y	81	11	DENV	denv	NN
cord-293701-u4ntxo0y	81	12	mixture	mixture	NN
cord-293701-u4ntxo0y	81	13	53	53	CD
cord-293701-u4ntxo0y	81	14	.	.	.
cord-293701-u4ntxo0y	82	1	However	however	RB
cord-293701-u4ntxo0y	82	2	,	,	,
cord-293701-u4ntxo0y	82	3	this	this	DT
cord-293701-u4ntxo0y	82	4	vaccine	vaccine	NN
cord-293701-u4ntxo0y	82	5	failed	fail	VBD
cord-293701-u4ntxo0y	82	6	to	to	TO
cord-293701-u4ntxo0y	82	7	protect	protect	VB
cord-293701-u4ntxo0y	82	8	the	the	DT
cord-293701-u4ntxo0y	82	9	participants	participant	NNS
cord-293701-u4ntxo0y	82	10	from	from	IN
cord-293701-u4ntxo0y	82	11	subsequent	subsequent	JJ
cord-293701-u4ntxo0y	82	12	DENV	DENV	NNP
cord-293701-u4ntxo0y	82	13	challenge	challenge	NN
cord-293701-u4ntxo0y	82	14	.	.	.
cord-293701-u4ntxo0y	83	1	Afterwards	afterwards	RB
cord-293701-u4ntxo0y	83	2	,	,	,
cord-293701-u4ntxo0y	83	3	many	many	JJ
cord-293701-u4ntxo0y	83	4	studies	study	NNS
cord-293701-u4ntxo0y	83	5	found	find	VBD
cord-293701-u4ntxo0y	83	6	that	that	IN
cord-293701-u4ntxo0y	83	7	natural	natural	JJ
cord-293701-u4ntxo0y	83	8	DENV	DENV	NNP
cord-293701-u4ntxo0y	83	9	infection	infection	NN
cord-293701-u4ntxo0y	83	10	induced	induce	VBD
cord-293701-u4ntxo0y	83	11	high	high	JJ
cord-293701-u4ntxo0y	83	12	-	-	HYPH
cord-293701-u4ntxo0y	83	13	titre	titre	NN
cord-293701-u4ntxo0y	83	14	and	and	CC
cord-293701-u4ntxo0y	83	15	sustained	sustain	VBD
cord-293701-u4ntxo0y	83	16	NAb	nab	JJ
cord-293701-u4ntxo0y	83	17	responses	response	NNS
cord-293701-u4ntxo0y	83	18	towards	towards	IN
cord-293701-u4ntxo0y	83	19	homologous	homologous	JJ
cord-293701-u4ntxo0y	83	20	DENV	DENV	NNP
cord-293701-u4ntxo0y	83	21	in	in	IN
cord-293701-u4ntxo0y	83	22	patients	patient	NNS
cord-293701-u4ntxo0y	83	23	54	54	CD
cord-293701-u4ntxo0y	83	24	,	,	,
cord-293701-u4ntxo0y	83	25	55	55	CD
cord-293701-u4ntxo0y	83	26	.	.	.
cord-293701-u4ntxo0y	84	1	A	a	DT
cord-293701-u4ntxo0y	84	2	group	group	NN
cord-293701-u4ntxo0y	84	3	of	of	IN
cord-293701-u4ntxo0y	84	4	researchers	researcher	NNS
cord-293701-u4ntxo0y	84	5	obtained	obtain	VBD
cord-293701-u4ntxo0y	84	6	an	an	DT
cord-293701-u4ntxo0y	84	7	attenuated	attenuated	JJ
cord-293701-u4ntxo0y	84	8	DENV	DENV	NNP
cord-293701-u4ntxo0y	84	9	strain	strain	NN
cord-293701-u4ntxo0y	84	10	by	by	IN
cord-293701-u4ntxo0y	84	11	serial	serial	JJ
cord-293701-u4ntxo0y	84	12	passage	passage	NN
cord-293701-u4ntxo0y	84	13	of	of	IN
cord-293701-u4ntxo0y	84	14	DENV	DENV	NNP
cord-293701-u4ntxo0y	84	15	in	in	IN
cord-293701-u4ntxo0y	84	16	mouse	mouse	NN
cord-293701-u4ntxo0y	84	17	brains	brain	NNS
cord-293701-u4ntxo0y	84	18	56	56	CD
cord-293701-u4ntxo0y	84	19	.	.	.
cord-293701-u4ntxo0y	85	1	One	one	CD
cord-293701-u4ntxo0y	85	2	dose	dose	NN
cord-293701-u4ntxo0y	85	3	of	of	IN
cord-293701-u4ntxo0y	85	4	the	the	DT
cord-293701-u4ntxo0y	85	5	attenuated	attenuated	JJ
cord-293701-u4ntxo0y	85	6	vaccine	vaccine	NN
cord-293701-u4ntxo0y	85	7	was	be	VBD
cord-293701-u4ntxo0y	85	8	adequate	adequate	JJ
cord-293701-u4ntxo0y	85	9	to	to	TO
cord-293701-u4ntxo0y	85	10	induce	induce	VB
cord-293701-u4ntxo0y	85	11	NAb	NAb	NNS
cord-293701-u4ntxo0y	85	12	in	in	IN
cord-293701-u4ntxo0y	85	13	vaccinated	vaccinated	JJ
cord-293701-u4ntxo0y	85	14	volunteers	volunteer	NNS
cord-293701-u4ntxo0y	85	15	.	.	.
cord-293701-u4ntxo0y	86	1	DENV	DENV	NNP
cord-293701-u4ntxo0y	86	2	has	have	VBZ
cord-293701-u4ntxo0y	86	3	four	four	CD
cord-293701-u4ntxo0y	86	4	serotypes	serotype	NNS
cord-293701-u4ntxo0y	86	5	(	(	-LRB-
cord-293701-u4ntxo0y	86	6	DENV1-DENV4	DENV1-DENV4	NNP
cord-293701-u4ntxo0y	86	7	)	)	-RRB-
cord-293701-u4ntxo0y	86	8	,	,	,
cord-293701-u4ntxo0y	86	9	which	which	WDT
cord-293701-u4ntxo0y	86	10	share	share	VBP
cord-293701-u4ntxo0y	86	11	a	a	DT
cord-293701-u4ntxo0y	86	12	considerable	considerable	JJ
cord-293701-u4ntxo0y	86	13	similarity	similarity	NN
cord-293701-u4ntxo0y	86	14	in	in	IN
cord-293701-u4ntxo0y	86	15	antigenic	antigenic	JJ
cord-293701-u4ntxo0y	86	16	epitopes	epitope	NNS
cord-293701-u4ntxo0y	86	17	.	.	.
cord-293701-u4ntxo0y	87	1	The	the	DT
cord-293701-u4ntxo0y	87	2	induced	induce	VBN
cord-293701-u4ntxo0y	87	3	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	87	4	not	not	RB
cord-293701-u4ntxo0y	87	5	only	only	RB
cord-293701-u4ntxo0y	87	6	protected	protect	VBD
cord-293701-u4ntxo0y	87	7	the	the	DT
cord-293701-u4ntxo0y	87	8	patient	patient	NN
cord-293701-u4ntxo0y	87	9	from	from	IN
cord-293701-u4ntxo0y	87	10	homologous	homologous	JJ
cord-293701-u4ntxo0y	87	11	viral	viral	JJ
cord-293701-u4ntxo0y	87	12	infection	infection	NN
cord-293701-u4ntxo0y	87	13	but	but	CC
cord-293701-u4ntxo0y	87	14	were	be	VBD
cord-293701-u4ntxo0y	87	15	also	also	RB
cord-293701-u4ntxo0y	87	16	cross	cross	JJ
cord-293701-u4ntxo0y	87	17	-	-	JJ
cord-293701-u4ntxo0y	87	18	reactive	reactive	JJ
cord-293701-u4ntxo0y	87	19	with	with	IN
cord-293701-u4ntxo0y	87	20	heterologous	heterologous	JJ
cord-293701-u4ntxo0y	87	21	DENVs	denv	NNS
cord-293701-u4ntxo0y	87	22	.	.	.
cord-293701-u4ntxo0y	88	1	However	however	RB
cord-293701-u4ntxo0y	88	2	,	,	,
cord-293701-u4ntxo0y	88	3	the	the	DT
cord-293701-u4ntxo0y	88	4	latter	latter	JJ
cord-293701-u4ntxo0y	88	5	protection	protection	NN
cord-293701-u4ntxo0y	88	6	was	be	VBD
cord-293701-u4ntxo0y	88	7	short	short	RB
cord-293701-u4ntxo0y	88	8	-	-	HYPH
cord-293701-u4ntxo0y	88	9	lived	live	VBN
cord-293701-u4ntxo0y	88	10	at	at	IN
cord-293701-u4ntxo0y	88	11	3	3	CD
cord-293701-u4ntxo0y	88	12	months	month	NNS
cord-293701-u4ntxo0y	88	13	to	to	IN
cord-293701-u4ntxo0y	88	14	2	2	CD
cord-293701-u4ntxo0y	88	15	years	year	NNS
cord-293701-u4ntxo0y	88	16	57	57	CD
cord-293701-u4ntxo0y	88	17	.	.	.
cord-293701-u4ntxo0y	89	1	Importantly	importantly	RB
cord-293701-u4ntxo0y	89	2	,	,	,
cord-293701-u4ntxo0y	89	3	the	the	DT
cord-293701-u4ntxo0y	89	4	cross	cross	JJ
cord-293701-u4ntxo0y	89	5	-	-	JJ
cord-293701-u4ntxo0y	89	6	specific	specific	JJ
cord-293701-u4ntxo0y	89	7	antibodies	antibody	NNS
cord-293701-u4ntxo0y	89	8	,	,	,
cord-293701-u4ntxo0y	89	9	once	once	RB
cord-293701-u4ntxo0y	89	10	falling	fall	VBG
cord-293701-u4ntxo0y	89	11	into	into	IN
cord-293701-u4ntxo0y	89	12	suboptimal	suboptimal	JJ
cord-293701-u4ntxo0y	89	13	concentrations	concentration	NNS
cord-293701-u4ntxo0y	89	14	,	,	,
cord-293701-u4ntxo0y	89	15	caused	cause	VBD
cord-293701-u4ntxo0y	89	16	a	a	DT
cord-293701-u4ntxo0y	89	17	higher	high	JJR
cord-293701-u4ntxo0y	89	18	risk	risk	NN
cord-293701-u4ntxo0y	89	19	of	of	IN
cord-293701-u4ntxo0y	89	20	severe	severe	JJ
cord-293701-u4ntxo0y	89	21	dengue	dengue	NN
cord-293701-u4ntxo0y	89	22	symptoms	symptom	NNS
cord-293701-u4ntxo0y	89	23	following	follow	VBG
cord-293701-u4ntxo0y	89	24	natural	natural	JJ
cord-293701-u4ntxo0y	89	25	infection	infection	NN
cord-293701-u4ntxo0y	89	26	with	with	IN
cord-293701-u4ntxo0y	89	27	heterologous	heterologous	JJ
cord-293701-u4ntxo0y	89	28	DENV	DENV	NNP
cord-293701-u4ntxo0y	89	29	than	than	IN
cord-293701-u4ntxo0y	89	30	in	in	IN
cord-293701-u4ntxo0y	89	31	naive	naive	JJ
cord-293701-u4ntxo0y	89	32	individuals	individual	NNS
cord-293701-u4ntxo0y	89	33	58	58	CD
cord-293701-u4ntxo0y	89	34	.	.	.
cord-293701-u4ntxo0y	90	1	This	this	DT
cord-293701-u4ntxo0y	90	2	phenomenon	phenomenon	NN
cord-293701-u4ntxo0y	90	3	was	be	VBD
cord-293701-u4ntxo0y	90	4	widely	widely	RB
cord-293701-u4ntxo0y	90	5	investigated	investigate	VBN
cord-293701-u4ntxo0y	90	6	.	.	.
cord-293701-u4ntxo0y	91	1	The	the	DT
cord-293701-u4ntxo0y	91	2	cross	cross	JJ
cord-293701-u4ntxo0y	91	3	-	-	JJ
cord-293701-u4ntxo0y	91	4	reactive	reactive	JJ
cord-293701-u4ntxo0y	91	5	antibodies	antibody	NNS
cord-293701-u4ntxo0y	91	6	bound	bind	VBN
cord-293701-u4ntxo0y	91	7	heterologous	heterologous	NNP
cord-293701-u4ntxo0y	91	8	DENV	DENV	NNP
cord-293701-u4ntxo0y	91	9	,	,	,
cord-293701-u4ntxo0y	91	10	thus	thus	RB
cord-293701-u4ntxo0y	91	11	facilitating	facilitate	VBG
cord-293701-u4ntxo0y	91	12	viral	viral	JJ
cord-293701-u4ntxo0y	91	13	entry	entry	NN
cord-293701-u4ntxo0y	91	14	into	into	IN
cord-293701-u4ntxo0y	91	15	target	target	NN
cord-293701-u4ntxo0y	91	16	cells	cell	NNS
cord-293701-u4ntxo0y	91	17	with	with	IN
cord-293701-u4ntxo0y	91	18	FcRs	FcRs	NNP
cord-293701-u4ntxo0y	91	19	,	,	,
cord-293701-u4ntxo0y	92	1	such	such	JJ
cord-293701-u4ntxo0y	92	2	In	in	IN
cord-293701-u4ntxo0y	92	3	the	the	DT
cord-293701-u4ntxo0y	92	4	normal	normal	JJ
cord-293701-u4ntxo0y	92	5	condition	condition	NN
cord-293701-u4ntxo0y	92	6	,	,	,
cord-293701-u4ntxo0y	92	7	when	when	WRB
cord-293701-u4ntxo0y	92	8	the	the	DT
cord-293701-u4ntxo0y	92	9	homologous	homologous	JJ
cord-293701-u4ntxo0y	92	10	virus	virus	NN
cord-293701-u4ntxo0y	92	11	enters	enter	VBZ
cord-293701-u4ntxo0y	92	12	an	an	DT
cord-293701-u4ntxo0y	92	13	immunized	immunize	VBN
cord-293701-u4ntxo0y	92	14	body	body	NN
cord-293701-u4ntxo0y	92	15	,	,	,
cord-293701-u4ntxo0y	92	16	it	-PRON-	PRP
cord-293701-u4ntxo0y	92	17	will	will	MD
cord-293701-u4ntxo0y	92	18	be	be	VB
cord-293701-u4ntxo0y	92	19	neutralized	neutralize	VBN
cord-293701-u4ntxo0y	92	20	or	or	CC
cord-293701-u4ntxo0y	92	21	cleared	clear	VBN
cord-293701-u4ntxo0y	92	22	by	by	IN
cord-293701-u4ntxo0y	92	23	vaccine	vaccine	NN
cord-293701-u4ntxo0y	92	24	-	-	HYPH
cord-293701-u4ntxo0y	92	25	induced	induce	VBN
cord-293701-u4ntxo0y	92	26	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	92	27	antibodies	antibody	NNS
cord-293701-u4ntxo0y	92	28	(	(	-LRB-
cord-293701-u4ntxo0y	92	29	Abs	abs	NN
cord-293701-u4ntxo0y	92	30	)	)	-RRB-
cord-293701-u4ntxo0y	92	31	or	or	CC
cord-293701-u4ntxo0y	92	32	specific	specific	JJ
cord-293701-u4ntxo0y	92	33	T	t	NN
cord-293701-u4ntxo0y	92	34	cells	cell	NNS
cord-293701-u4ntxo0y	92	35	,	,	,
cord-293701-u4ntxo0y	92	36	respectively	respectively	RB
cord-293701-u4ntxo0y	92	37	.	.	.
cord-293701-u4ntxo0y	93	1	In	in	IN
cord-293701-u4ntxo0y	93	2	the	the	DT
cord-293701-u4ntxo0y	93	3	context	context	NN
cord-293701-u4ntxo0y	93	4	of	of	IN
cord-293701-u4ntxo0y	93	5	vaccine	vaccine	NN
cord-293701-u4ntxo0y	93	6	-	-	HYPH
cord-293701-u4ntxo0y	93	7	associated	associate	VBN
cord-293701-u4ntxo0y	93	8	disease	disease	NN
cord-293701-u4ntxo0y	93	9	enhancement	enhancement	NN
cord-293701-u4ntxo0y	93	10	,	,	,
cord-293701-u4ntxo0y	93	11	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	93	12	mainly	mainly	RB
cord-293701-u4ntxo0y	93	13	induce	induce	VBP
cord-293701-u4ntxo0y	93	14	non	non	JJ
cord-293701-u4ntxo0y	93	15	-	-	JJ
cord-293701-u4ntxo0y	93	16	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	93	17	Abs	abs	NN
cord-293701-u4ntxo0y	93	18	or	or	CC
cord-293701-u4ntxo0y	93	19	low	low	JJ
cord-293701-u4ntxo0y	93	20	titres	titre	NNS
cord-293701-u4ntxo0y	93	21	of	of	IN
cord-293701-u4ntxo0y	93	22	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	93	23	Abs	abs	NN
cord-293701-u4ntxo0y	93	24	(	(	-LRB-
cord-293701-u4ntxo0y	93	25	suboptimal	suboptimal	JJ
cord-293701-u4ntxo0y	93	26	concentration	concentration	NN
cord-293701-u4ntxo0y	93	27	)	)	-RRB-
cord-293701-u4ntxo0y	93	28	or	or	CC
cord-293701-u4ntxo0y	93	29	type	type	NN
cord-293701-u4ntxo0y	93	30	2	2	CD
cord-293701-u4ntxo0y	93	31	T	t	NN
cord-293701-u4ntxo0y	93	32	helper	helper	NN
cord-293701-u4ntxo0y	93	33	cell	cell	NN
cord-293701-u4ntxo0y	93	34	(	(	-LRB-
cord-293701-u4ntxo0y	93	35	T	T	NNP
cord-293701-u4ntxo0y	93	36	H	h	NN
cord-293701-u4ntxo0y	93	37	2	2	CD
cord-293701-u4ntxo0y	93	38	cell)-biased	cell)-biased	NNP
cord-293701-u4ntxo0y	93	39	T	t	NN
cord-293701-u4ntxo0y	93	40	cell	cell	NN
cord-293701-u4ntxo0y	93	41	responses	response	NNS
cord-293701-u4ntxo0y	93	42	.	.	.
cord-293701-u4ntxo0y	94	1	When	when	WRB
cord-293701-u4ntxo0y	94	2	these	these	DT
cord-293701-u4ntxo0y	94	3	vaccinated	vaccinate	VBN
cord-293701-u4ntxo0y	94	4	individuals	individual	NNS
cord-293701-u4ntxo0y	94	5	are	be	VBP
cord-293701-u4ntxo0y	94	6	challenged	challenge	VBN
cord-293701-u4ntxo0y	94	7	by	by	IN
cord-293701-u4ntxo0y	94	8	homotypic	homotypic	NNP
cord-293701-u4ntxo0y	94	9	or	or	CC
cord-293701-u4ntxo0y	94	10	heterotypic	heterotypic	NNP
cord-293701-u4ntxo0y	94	11	serotype	serotype	NN
cord-293701-u4ntxo0y	94	12	viruses	virus	NNS
cord-293701-u4ntxo0y	94	13	,	,	,
cord-293701-u4ntxo0y	94	14	the	the	DT
cord-293701-u4ntxo0y	94	15	antibodies	antibody	NNS
cord-293701-u4ntxo0y	94	16	will	will	MD
cord-293701-u4ntxo0y	94	17	immediately	immediately	RB
cord-293701-u4ntxo0y	94	18	recognize	recognize	VB
cord-293701-u4ntxo0y	94	19	the	the	DT
cord-293701-u4ntxo0y	94	20	viruses	virus	NNS
cord-293701-u4ntxo0y	94	21	and	and	CC
cord-293701-u4ntxo0y	94	22	mediate	mediate	VB
cord-293701-u4ntxo0y	94	23	antibody	antibody	NN
cord-293701-u4ntxo0y	94	24	-	-	HYPH
cord-293701-u4ntxo0y	94	25	dependent	dependent	JJ
cord-293701-u4ntxo0y	94	26	disease	disease	NN
cord-293701-u4ntxo0y	94	27	exacerbation	exacerbation	NN
cord-293701-u4ntxo0y	94	28	in	in	IN
cord-293701-u4ntxo0y	94	29	two	two	CD
cord-293701-u4ntxo0y	94	30	ways	way	NNS
cord-293701-u4ntxo0y	94	31	.	.	.
cord-293701-u4ntxo0y	95	1	First	first	RB
cord-293701-u4ntxo0y	95	2	,	,	,
cord-293701-u4ntxo0y	95	3	virus	virus	NN
cord-293701-u4ntxo0y	95	4	-	-	HYPH
cord-293701-u4ntxo0y	95	5	antibody	antibody	NN
cord-293701-u4ntxo0y	95	6	complexes	complex	NNS
cord-293701-u4ntxo0y	95	7	might	may	MD
cord-293701-u4ntxo0y	95	8	enter	enter	VB
cord-293701-u4ntxo0y	95	9	Fc	Fc	NNP
cord-293701-u4ntxo0y	95	10	receptor	receptor	NN
cord-293701-u4ntxo0y	95	11	(	(	-LRB-
cord-293701-u4ntxo0y	95	12	FcR)-bearing	fcr)-beare	VBG
cord-293701-u4ntxo0y	95	13	cells	cell	NNS
cord-293701-u4ntxo0y	95	14	,	,	,
cord-293701-u4ntxo0y	95	15	such	such	JJ
cord-293701-u4ntxo0y	95	16	as	as	IN
cord-293701-u4ntxo0y	95	17	dendritic	dendritic	JJ
cord-293701-u4ntxo0y	95	18	cells	cell	NNS
cord-293701-u4ntxo0y	95	19	and	and	CC
cord-293701-u4ntxo0y	95	20	monocytes	monocyte	NNS
cord-293701-u4ntxo0y	95	21	,	,	,
cord-293701-u4ntxo0y	95	22	by	by	IN
cord-293701-u4ntxo0y	95	23	FcR	fcr	NN
cord-293701-u4ntxo0y	95	24	-	-	HYPH
cord-293701-u4ntxo0y	95	25	mediated	mediate	VBN
cord-293701-u4ntxo0y	95	26	internalization	internalization	NN
cord-293701-u4ntxo0y	95	27	,	,	,
cord-293701-u4ntxo0y	95	28	which	which	WDT
cord-293701-u4ntxo0y	95	29	is	be	VBZ
cord-293701-u4ntxo0y	95	30	termed	term	VBN
cord-293701-u4ntxo0y	95	31	'	'	``
cord-293701-u4ntxo0y	95	32	antibody	antibody	NN
cord-293701-u4ntxo0y	95	33	-	-	HYPH
cord-293701-u4ntxo0y	95	34	dependent	dependent	JJ
cord-293701-u4ntxo0y	95	35	enhancement	enhancement	NN
cord-293701-u4ntxo0y	95	36	'	'	''
cord-293701-u4ntxo0y	95	37	(	(	-LRB-
cord-293701-u4ntxo0y	95	38	ADE	ADE	NNP
cord-293701-u4ntxo0y	95	39	)	)	-RRB-
cord-293701-u4ntxo0y	95	40	.	.	.
cord-293701-u4ntxo0y	96	1	For	for	IN
cord-293701-u4ntxo0y	96	2	viruses	virus	NNS
cord-293701-u4ntxo0y	96	3	with	with	IN
cord-293701-u4ntxo0y	96	4	innate	innate	JJ
cord-293701-u4ntxo0y	96	5	tropism	tropism	NN
cord-293701-u4ntxo0y	96	6	for	for	IN
cord-293701-u4ntxo0y	96	7	FcR	fcr	NN
cord-293701-u4ntxo0y	96	8	-	-	HYPH
cord-293701-u4ntxo0y	96	9	bearing	bear	VBG
cord-293701-u4ntxo0y	96	10	cells	cell	NNS
cord-293701-u4ntxo0y	96	11	,	,	,
cord-293701-u4ntxo0y	96	12	such	such	JJ
cord-293701-u4ntxo0y	96	13	as	as	IN
cord-293701-u4ntxo0y	96	14	dengue	dengue	NN
cord-293701-u4ntxo0y	96	15	virus	virus	NN
cord-293701-u4ntxo0y	96	16	,	,	,
cord-293701-u4ntxo0y	96	17	ADE	ADE	NNP
cord-293701-u4ntxo0y	96	18	will	will	MD
cord-293701-u4ntxo0y	96	19	result	result	VB
cord-293701-u4ntxo0y	96	20	in	in	IN
cord-293701-u4ntxo0y	96	21	higher	high	JJR
cord-293701-u4ntxo0y	96	22	viral	viral	JJ
cord-293701-u4ntxo0y	96	23	loads	load	NNS
cord-293701-u4ntxo0y	96	24	than	than	IN
cord-293701-u4ntxo0y	96	25	in	in	IN
cord-293701-u4ntxo0y	96	26	conditions	condition	NNS
cord-293701-u4ntxo0y	96	27	without	without	IN
cord-293701-u4ntxo0y	96	28	antibodies	antibody	NNS
cord-293701-u4ntxo0y	96	29	.	.	.
cord-293701-u4ntxo0y	97	1	a	a	DT
cord-293701-u4ntxo0y	97	2	|	|	CD
cord-293701-u4ntxo0y	98	1	After	after	IN
cord-293701-u4ntxo0y	98	2	entry	entry	NN
cord-293701-u4ntxo0y	98	3	,	,	,
cord-293701-u4ntxo0y	98	4	the	the	DT
cord-293701-u4ntxo0y	98	5	virus	virus	NN
cord-293701-u4ntxo0y	98	6	,	,	,
cord-293701-u4ntxo0y	98	7	no	no	RB
cord-293701-u4ntxo0y	98	8	matter	matter	RB
cord-293701-u4ntxo0y	98	9	whether	whether	IN
cord-293701-u4ntxo0y	98	10	it	-PRON-	PRP
cord-293701-u4ntxo0y	98	11	replicates	replicate	VBZ
cord-293701-u4ntxo0y	98	12	or	or	CC
cord-293701-u4ntxo0y	98	13	does	do	VBZ
cord-293701-u4ntxo0y	98	14	not	not	RB
cord-293701-u4ntxo0y	98	15	replicate	replicate	VB
cord-293701-u4ntxo0y	98	16	,	,	,
cord-293701-u4ntxo0y	98	17	may	may	MD
cord-293701-u4ntxo0y	98	18	activate	activate	VB
cord-293701-u4ntxo0y	98	19	a	a	DT
cord-293701-u4ntxo0y	98	20	harmful	harmful	JJ
cord-293701-u4ntxo0y	98	21	immune	immune	JJ
cord-293701-u4ntxo0y	98	22	response	response	NN
cord-293701-u4ntxo0y	98	23	,	,	,
cord-293701-u4ntxo0y	98	24	resulting	result	VBG
cord-293701-u4ntxo0y	98	25	in	in	IN
cord-293701-u4ntxo0y	98	26	the	the	DT
cord-293701-u4ntxo0y	98	27	release	release	NN
cord-293701-u4ntxo0y	98	28	of	of	IN
cord-293701-u4ntxo0y	98	29	proinflammatory	proinflammatory	JJ
cord-293701-u4ntxo0y	98	30	cytokines	cytokine	NNS
cord-293701-u4ntxo0y	98	31	.	.	.
cord-293701-u4ntxo0y	99	1	b	b	LS
cord-293701-u4ntxo0y	99	2	|	|	NNP
cord-293701-u4ntxo0y	100	1	Aside	aside	RB
cord-293701-u4ntxo0y	100	2	from	from	IN
cord-293701-u4ntxo0y	100	3	ADE	ADE	NNP
cord-293701-u4ntxo0y	100	4	,	,	,
cord-293701-u4ntxo0y	100	5	antibody	antibody	NN
cord-293701-u4ntxo0y	100	6	-	-	HYPH
cord-293701-u4ntxo0y	100	7	antigen	antigen	NN
cord-293701-u4ntxo0y	100	8	complexes	complex	NNS
cord-293701-u4ntxo0y	100	9	can	can	MD
cord-293701-u4ntxo0y	100	10	stimulate	stimulate	VB
cord-293701-u4ntxo0y	100	11	the	the	DT
cord-293701-u4ntxo0y	100	12	complement	complement	JJ
cord-293701-u4ntxo0y	100	13	pathway	pathway	NN
cord-293701-u4ntxo0y	100	14	through	through	IN
cord-293701-u4ntxo0y	100	15	activation	activation	NN
cord-293701-u4ntxo0y	100	16	of	of	IN
cord-293701-u4ntxo0y	100	17	the	the	DT
cord-293701-u4ntxo0y	100	18	C1q	C1q	NNP
cord-293701-u4ntxo0y	100	19	pathway	pathway	NN
cord-293701-u4ntxo0y	100	20	,	,	,
cord-293701-u4ntxo0y	100	21	thus	thus	RB
cord-293701-u4ntxo0y	100	22	further	further	RB
cord-293701-u4ntxo0y	100	23	strengthening	strengthen	VBG
cord-293701-u4ntxo0y	100	24	the	the	DT
cord-293701-u4ntxo0y	100	25	inflammatory	inflammatory	JJ
cord-293701-u4ntxo0y	100	26	responses	response	NNS
cord-293701-u4ntxo0y	100	27	c	c	NN
cord-293701-u4ntxo0y	100	28	|	|	:
cord-293701-u4ntxo0y	100	29	Vaccine	vaccine	NN
cord-293701-u4ntxo0y	100	30	-	-	HYPH
cord-293701-u4ntxo0y	100	31	associated	associate	VBN
cord-293701-u4ntxo0y	100	32	disease	disease	NN
cord-293701-u4ntxo0y	100	33	enhancement	enhancement	NN
cord-293701-u4ntxo0y	100	34	can	can	MD
cord-293701-u4ntxo0y	100	35	also	also	RB
cord-293701-u4ntxo0y	100	36	involve	involve	VB
cord-293701-u4ntxo0y	100	37	a	a	DT
cord-293701-u4ntxo0y	100	38	T	t	NN
cord-293701-u4ntxo0y	100	39	H	h	NN
cord-293701-u4ntxo0y	100	40	2	2	CD
cord-293701-u4ntxo0y	100	41	cell	cell	NN
cord-293701-u4ntxo0y	100	42	-	-	HYPH
cord-293701-u4ntxo0y	100	43	biased	bias	VBN
cord-293701-u4ntxo0y	100	44	immune	immune	JJ
cord-293701-u4ntxo0y	100	45	response	response	NN
cord-293701-u4ntxo0y	100	46	.	.	.
cord-293701-u4ntxo0y	101	1	The	the	DT
cord-293701-u4ntxo0y	101	2	activated	activate	VBN
cord-293701-u4ntxo0y	101	3	T	t	NN
cord-293701-u4ntxo0y	101	4	H	h	NN
cord-293701-u4ntxo0y	101	5	2	2	CD
cord-293701-u4ntxo0y	101	6	cells	cell	NNS
cord-293701-u4ntxo0y	101	7	contribute	contribute	VBP
cord-293701-u4ntxo0y	101	8	to	to	IN
cord-293701-u4ntxo0y	101	9	the	the	DT
cord-293701-u4ntxo0y	101	10	activation	activation	NN
cord-293701-u4ntxo0y	101	11	of	of	IN
cord-293701-u4ntxo0y	101	12	antibody	antibody	NN
cord-293701-u4ntxo0y	101	13	production	production	NN
cord-293701-u4ntxo0y	101	14	.	.	.
cord-293701-u4ntxo0y	102	1	However	however	RB
cord-293701-u4ntxo0y	102	2	,	,	,
cord-293701-u4ntxo0y	102	3	they	-PRON-	PRP
cord-293701-u4ntxo0y	102	4	release	release	VBP
cord-293701-u4ntxo0y	102	5	interleukin-4	interleukin-4	NNP
cord-293701-u4ntxo0y	102	6	(	(	-LRB-
cord-293701-u4ntxo0y	102	7	IL-4	IL-4	NNP
cord-293701-u4ntxo0y	102	8	)	)	-RRB-
cord-293701-u4ntxo0y	102	9	,	,	,
cord-293701-u4ntxo0y	102	10	IL-13	IL-13	NNP
cord-293701-u4ntxo0y	102	11	and	and	CC
cord-293701-u4ntxo0y	102	12	IL-5	IL-5	NNP
cord-293701-u4ntxo0y	102	13	,	,	,
cord-293701-u4ntxo0y	102	14	as	as	RB
cord-293701-u4ntxo0y	102	15	well	well	RB
cord-293701-u4ntxo0y	102	16	as	as	IN
cord-293701-u4ntxo0y	102	17	eosinophil	eosinophil	JJ
cord-293701-u4ntxo0y	102	18	chemoattractant	chemoattractant	NN
cord-293701-u4ntxo0y	102	19	,	,	,
cord-293701-u4ntxo0y	102	20	thus	thus	RB
cord-293701-u4ntxo0y	102	21	resulting	result	VBG
cord-293701-u4ntxo0y	102	22	in	in	IN
cord-293701-u4ntxo0y	102	23	eosinophil	eosinophil	JJ
cord-293701-u4ntxo0y	102	24	infiltration	infiltration	NN
cord-293701-u4ntxo0y	102	25	and	and	CC
cord-293701-u4ntxo0y	102	26	proinflammatory	proinflammatory	JJ
cord-293701-u4ntxo0y	102	27	cytokine	cytokine	NN
cord-293701-u4ntxo0y	102	28	production	production	NN
cord-293701-u4ntxo0y	102	29	in	in	IN
cord-293701-u4ntxo0y	102	30	the	the	DT
cord-293701-u4ntxo0y	102	31	lung	lung	NN
cord-293701-u4ntxo0y	102	32	.	.	.
cord-293701-u4ntxo0y	103	1	d	d	NNP
cord-293701-u4ntxo0y	103	2	|	|	NNP
cord-293701-u4ntxo0y	103	3	Natural	Natural	NNP
cord-293701-u4ntxo0y	103	4	killer	killer	NN
cord-293701-u4ntxo0y	103	5	(	(	-LRB-
cord-293701-u4ntxo0y	103	6	NK	NK	NNP
cord-293701-u4ntxo0y	103	7	)	)	-RRB-
cord-293701-u4ntxo0y	103	8	cells	cell	NNS
cord-293701-u4ntxo0y	103	9	and	and	CC
cord-293701-u4ntxo0y	103	10	CD8	CD8	NNP
cord-293701-u4ntxo0y	103	11	+	+	CC
cord-293701-u4ntxo0y	103	12	cytotoxic	cytotoxic	JJ
cord-293701-u4ntxo0y	103	13	T	t	NN
cord-293701-u4ntxo0y	103	14	lymphocytes	lymphocyte	NNS
cord-293701-u4ntxo0y	103	15	(	(	-LRB-
cord-293701-u4ntxo0y	103	16	CTLs	CTLs	NNP
cord-293701-u4ntxo0y	103	17	)	)	-RRB-
cord-293701-u4ntxo0y	103	18	are	be	VBP
cord-293701-u4ntxo0y	103	19	poorly	poorly	RB
cord-293701-u4ntxo0y	103	20	stimulated	stimulate	VBN
cord-293701-u4ntxo0y	103	21	in	in	IN
cord-293701-u4ntxo0y	103	22	T	T	NNP
cord-293701-u4ntxo0y	103	23	H	h	NN
cord-293701-u4ntxo0y	103	24	2	2	CD
cord-293701-u4ntxo0y	103	25	cell	cell	NN
cord-293701-u4ntxo0y	103	26	-	-	HYPH
cord-293701-u4ntxo0y	103	27	skewed	skew	VBN
cord-293701-u4ntxo0y	103	28	immune	immune	JJ
cord-293701-u4ntxo0y	103	29	responses	response	NNS
cord-293701-u4ntxo0y	103	30	.	.	.
cord-293701-u4ntxo0y	104	1	The	the	DT
cord-293701-u4ntxo0y	104	2	exaggerated	exaggerated	JJ
cord-293701-u4ntxo0y	104	3	cytokine	cytokine	NN
cord-293701-u4ntxo0y	104	4	release	release	NN
cord-293701-u4ntxo0y	104	5	(	(	-LRB-
cord-293701-u4ntxo0y	104	6	part	part	NN
cord-293701-u4ntxo0y	104	7	b	b	NNP
cord-293701-u4ntxo0y	104	8	)	)	-RRB-
cord-293701-u4ntxo0y	104	9	,	,	,
cord-293701-u4ntxo0y	104	10	activation	activation	NN
cord-293701-u4ntxo0y	104	11	of	of	IN
cord-293701-u4ntxo0y	104	12	the	the	DT
cord-293701-u4ntxo0y	104	13	complement	complement	JJ
cord-293701-u4ntxo0y	104	14	pathway	pathway	NN
cord-293701-u4ntxo0y	104	15	(	(	-LRB-
cord-293701-u4ntxo0y	104	16	part	part	NN
cord-293701-u4ntxo0y	104	17	c	c	NNP
cord-293701-u4ntxo0y	104	18	)	)	-RRB-
cord-293701-u4ntxo0y	104	19	and	and	CC
cord-293701-u4ntxo0y	104	20	the	the	DT
cord-293701-u4ntxo0y	104	21	excessive	excessive	JJ
cord-293701-u4ntxo0y	104	22	mobilization	mobilization	NN
cord-293701-u4ntxo0y	104	23	of	of	IN
cord-293701-u4ntxo0y	104	24	eosinophils	eosinophil	NNS
cord-293701-u4ntxo0y	104	25	all	all	DT
cord-293701-u4ntxo0y	104	26	contribute	contribute	VBP
cord-293701-u4ntxo0y	104	27	to	to	IN
cord-293701-u4ntxo0y	104	28	the	the	DT
cord-293701-u4ntxo0y	104	29	infiltration	infiltration	NN
cord-293701-u4ntxo0y	104	30	of	of	IN
cord-293701-u4ntxo0y	104	31	the	the	DT
cord-293701-u4ntxo0y	104	32	lung	lung	NN
cord-293701-u4ntxo0y	104	33	by	by	IN
cord-293701-u4ntxo0y	104	34	eosinophils	eosinophil	NNS
cord-293701-u4ntxo0y	104	35	,	,	,
cord-293701-u4ntxo0y	104	36	neutrophils	neutrophil	NNS
cord-293701-u4ntxo0y	104	37	and	and	CC
cord-293701-u4ntxo0y	104	38	lymphocytes	lymphocyte	NNS
cord-293701-u4ntxo0y	104	39	,	,	,
cord-293701-u4ntxo0y	104	40	and	and	CC
cord-293701-u4ntxo0y	104	41	production	production	NN
cord-293701-u4ntxo0y	104	42	of	of	IN
cord-293701-u4ntxo0y	104	43	inflammatory	inflammatory	JJ
cord-293701-u4ntxo0y	104	44	cytokines	cytokine	NNS
cord-293701-u4ntxo0y	104	45	(	(	-LRB-
cord-293701-u4ntxo0y	104	46	part	part	NN
cord-293701-u4ntxo0y	104	47	d	d	NNP
cord-293701-u4ntxo0y	104	48	)	)	-RRB-
cord-293701-u4ntxo0y	104	49	,	,	,
cord-293701-u4ntxo0y	104	50	leading	lead	VBG
cord-293701-u4ntxo0y	104	51	to	to	IN
cord-293701-u4ntxo0y	104	52	acute	acute	JJ
cord-293701-u4ntxo0y	104	53	lung	lung	NN
cord-293701-u4ntxo0y	104	54	injury	injury	NN
cord-293701-u4ntxo0y	104	55	or	or	CC
cord-293701-u4ntxo0y	104	56	acute	acute	JJ
cord-293701-u4ntxo0y	104	57	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	104	58	distress	distress	NN
cord-293701-u4ntxo0y	104	59	syndrome	syndrome	NN
cord-293701-u4ntxo0y	104	60	.	.	.
cord-293701-u4ntxo0y	105	1	as	as	IN
cord-293701-u4ntxo0y	105	2	monocytes	monocyte	NNS
cord-293701-u4ntxo0y	105	3	,	,	,
cord-293701-u4ntxo0y	105	4	macrophages	macrophage	NNS
cord-293701-u4ntxo0y	105	5	and	and	CC
cord-293701-u4ntxo0y	105	6	dendritic	dendritic	JJ
cord-293701-u4ntxo0y	105	7	cells	cell	NNS
cord-293701-u4ntxo0y	105	8	19	19	CD
cord-293701-u4ntxo0y	105	9	,	,	,
cord-293701-u4ntxo0y	105	10	59	59	CD
cord-293701-u4ntxo0y	105	11	.	.	.
cord-293701-u4ntxo0y	106	1	Meanwhile	meanwhile	RB
cord-293701-u4ntxo0y	106	2	,	,	,
cord-293701-u4ntxo0y	106	3	epidemiological	epidemiological	JJ
cord-293701-u4ntxo0y	106	4	studies	study	NNS
cord-293701-u4ntxo0y	106	5	showed	show	VBD
cord-293701-u4ntxo0y	106	6	that	that	IN
cord-293701-u4ntxo0y	106	7	the	the	DT
cord-293701-u4ntxo0y	106	8	occurrence	occurrence	NN
cord-293701-u4ntxo0y	106	9	of	of	IN
cord-293701-u4ntxo0y	106	10	severe	severe	JJ
cord-293701-u4ntxo0y	106	11	dengue	dengue	NN
cord-293701-u4ntxo0y	106	12	was	be	VBD
cord-293701-u4ntxo0y	106	13	associated	associate	VBN
cord-293701-u4ntxo0y	106	14	with	with	IN
cord-293701-u4ntxo0y	106	15	a	a	DT
cord-293701-u4ntxo0y	106	16	certain	certain	JJ
cord-293701-u4ntxo0y	106	17	range	range	NN
cord-293701-u4ntxo0y	106	18	(	(	-LRB-
cord-293701-u4ntxo0y	106	19	DENV	DENV	NNP
cord-293701-u4ntxo0y	106	20	antibody	antibody	NN
cord-293701-u4ntxo0y	106	21	titres	titre	NNS
cord-293701-u4ntxo0y	106	22	of	of	IN
cord-293701-u4ntxo0y	106	23	1:21	1:21	CD
cord-293701-u4ntxo0y	106	24	to	to	IN
cord-293701-u4ntxo0y	106	25	1:80	1:80	CD
cord-293701-u4ntxo0y	106	26	)	)	-RRB-
cord-293701-u4ntxo0y	106	27	of	of	IN
cord-293701-u4ntxo0y	106	28	cross	cross	JJ
cord-293701-u4ntxo0y	106	29	-	-	JJ
cord-293701-u4ntxo0y	106	30	reactive	reactive	JJ
cord-293701-u4ntxo0y	106	31	antibody	antibody	NN
cord-293701-u4ntxo0y	106	32	titres	titre	NNS
cord-293701-u4ntxo0y	106	33	60	60	CD
cord-293701-u4ntxo0y	106	34	,	,	,
cord-293701-u4ntxo0y	106	35	61	61	CD
cord-293701-u4ntxo0y	106	36	.	.	.
cord-293701-u4ntxo0y	107	1	Aside	aside	RB
cord-293701-u4ntxo0y	107	2	from	from	IN
cord-293701-u4ntxo0y	107	3	entry	entry	NN
cord-293701-u4ntxo0y	107	4	enhancement	enhancement	NN
cord-293701-u4ntxo0y	107	5	,	,	,
cord-293701-u4ntxo0y	107	6	non	non	NNP
cord-293701-u4ntxo0y	107	7	-	-	NNP
cord-293701-u4ntxo0y	107	8	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	107	9	,	,	,
cord-293701-u4ntxo0y	107	10	or	or	CC
cord-293701-u4ntxo0y	107	11	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	107	12	below	below	IN
cord-293701-u4ntxo0y	107	13	the	the	DT
cord-293701-u4ntxo0y	107	14	optimal	optimal	JJ
cord-293701-u4ntxo0y	107	15	concentration	concentration	NN
cord-293701-u4ntxo0y	107	16	,	,	,
cord-293701-u4ntxo0y	107	17	could	could	MD
cord-293701-u4ntxo0y	107	18	form	form	VB
cord-293701-u4ntxo0y	107	19	complexes	complex	NNS
cord-293701-u4ntxo0y	107	20	with	with	IN
cord-293701-u4ntxo0y	107	21	DENV	DENV	NNP
cord-293701-u4ntxo0y	107	22	particles	particle	NNS
cord-293701-u4ntxo0y	107	23	,	,	,
cord-293701-u4ntxo0y	107	24	which	which	WDT
cord-293701-u4ntxo0y	107	25	then	then	RB
cord-293701-u4ntxo0y	107	26	induced	induce	VBD
cord-293701-u4ntxo0y	107	27	inflammatory	inflammatory	JJ
cord-293701-u4ntxo0y	107	28	responses	response	NNS
cord-293701-u4ntxo0y	107	29	through	through	IN
cord-293701-u4ntxo0y	107	30	the	the	DT
cord-293701-u4ntxo0y	107	31	FcR	fcr	NN
cord-293701-u4ntxo0y	107	32	-	-	HYPH
cord-293701-u4ntxo0y	107	33	mediated	mediate	VBN
cord-293701-u4ntxo0y	107	34	immune	immune	JJ
cord-293701-u4ntxo0y	107	35	regulatory	regulatory	JJ
cord-293701-u4ntxo0y	107	36	pathway	pathway	NN
cord-293701-u4ntxo0y	107	37	62	62	CD
cord-293701-u4ntxo0y	107	38	,	,	,
cord-293701-u4ntxo0y	107	39	further	further	RB
cord-293701-u4ntxo0y	107	40	increasing	increase	VBG
cord-293701-u4ntxo0y	107	41	the	the	DT
cord-293701-u4ntxo0y	107	42	risk	risk	NN
cord-293701-u4ntxo0y	107	43	of	of	IN
cord-293701-u4ntxo0y	107	44	severe	severe	JJ
cord-293701-u4ntxo0y	107	45	dengue	dengue	NN
cord-293701-u4ntxo0y	107	46	.	.	.
cord-293701-u4ntxo0y	108	1	It	-PRON-	PRP
cord-293701-u4ntxo0y	108	2	was	be	VBD
cord-293701-u4ntxo0y	108	3	clear	clear	JJ
cord-293701-u4ntxo0y	108	4	that	that	IN
cord-293701-u4ntxo0y	108	5	reinfection	reinfection	NN
cord-293701-u4ntxo0y	108	6	by	by	IN
cord-293701-u4ntxo0y	108	7	heterotypic	heterotypic	NNP
cord-293701-u4ntxo0y	108	8	serotype	serotype	NN
cord-293701-u4ntxo0y	108	9	DENV	DENV	NNP
cord-293701-u4ntxo0y	108	10	resulted	result	VBD
cord-293701-u4ntxo0y	108	11	in	in	IN
cord-293701-u4ntxo0y	108	12	ADE	ADE	NNP
cord-293701-u4ntxo0y	108	13	.	.	.
cord-293701-u4ntxo0y	109	1	Therefore	therefore	RB
cord-293701-u4ntxo0y	109	2	,	,	,
cord-293701-u4ntxo0y	109	3	the	the	DT
cord-293701-u4ntxo0y	109	4	next	next	JJ
cord-293701-u4ntxo0y	109	5	challenge	challenge	NN
cord-293701-u4ntxo0y	109	6	in	in	IN
cord-293701-u4ntxo0y	109	7	dengue	dengue	NN
cord-293701-u4ntxo0y	109	8	vaccine	vaccine	NN
cord-293701-u4ntxo0y	109	9	development	development	NN
cord-293701-u4ntxo0y	109	10	was	be	VBD
cord-293701-u4ntxo0y	109	11	the	the	DT
cord-293701-u4ntxo0y	109	12	induction	induction	NN
cord-293701-u4ntxo0y	109	13	of	of	IN
cord-293701-u4ntxo0y	109	14	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	109	15	against	against	IN
cord-293701-u4ntxo0y	109	16	all	all	DT
cord-293701-u4ntxo0y	109	17	four	four	CD
cord-293701-u4ntxo0y	109	18	DENV	DENV	NNP
cord-293701-u4ntxo0y	109	19	serotypes	serotype	NNS
cord-293701-u4ntxo0y	109	20	.	.	.
cord-293701-u4ntxo0y	110	1	It	-PRON-	PRP
cord-293701-u4ntxo0y	110	2	was	be	VBD
cord-293701-u4ntxo0y	110	3	not	not	RB
cord-293701-u4ntxo0y	110	4	until	until	IN
cord-293701-u4ntxo0y	110	5	2006	2006	CD
cord-293701-u4ntxo0y	110	6	,	,	,
cord-293701-u4ntxo0y	110	7	77	77	CD
cord-293701-u4ntxo0y	110	8	years	year	NNS
cord-293701-u4ntxo0y	110	9	after	after	IN
cord-293701-u4ntxo0y	110	10	the	the	DT
cord-293701-u4ntxo0y	110	11	first	first	JJ
cord-293701-u4ntxo0y	110	12	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	110	13	dengue	dengue	NN
cord-293701-u4ntxo0y	110	14	vaccine	vaccine	NN
cord-293701-u4ntxo0y	110	15	had	have	VBD
cord-293701-u4ntxo0y	110	16	been	be	VBN
cord-293701-u4ntxo0y	110	17	tested	test	VBN
cord-293701-u4ntxo0y	110	18	in	in	IN
cord-293701-u4ntxo0y	110	19	humans	human	NNS
cord-293701-u4ntxo0y	110	20	,	,	,
cord-293701-u4ntxo0y	110	21	that	that	IN
cord-293701-u4ntxo0y	110	22	the	the	DT
cord-293701-u4ntxo0y	110	23	first	first	JJ
cord-293701-u4ntxo0y	110	24	tetravalent	tetravalent	NN
cord-293701-u4ntxo0y	110	25	dengue	dengue	NN
cord-293701-u4ntxo0y	110	26	vaccine	vaccine	NN
cord-293701-u4ntxo0y	110	27	,	,	,
cord-293701-u4ntxo0y	110	28	CYD	CYD	NNP
cord-293701-u4ntxo0y	110	29	-	-	HYPH
cord-293701-u4ntxo0y	110	30	TDV	TDV	NNP
cord-293701-u4ntxo0y	110	31	,	,	,
cord-293701-u4ntxo0y	110	32	entered	enter	VBD
cord-293701-u4ntxo0y	110	33	clinical	clinical	JJ
cord-293701-u4ntxo0y	110	34	trials	trial	NNS
cord-293701-u4ntxo0y	110	35	(	(	-LRB-
cord-293701-u4ntxo0y	110	36	NCT00384670	NCT00384670	NNP
cord-293701-u4ntxo0y	110	37	)	)	-RRB-
cord-293701-u4ntxo0y	110	38	.	.	.
cord-293701-u4ntxo0y	111	1	CYD	CYD	NNP
cord-293701-u4ntxo0y	111	2	-	-	HYPH
cord-293701-u4ntxo0y	111	3	TDV	TDV	NNP
cord-293701-u4ntxo0y	111	4	is	be	VBZ
cord-293701-u4ntxo0y	111	5	a	a	DT
cord-293701-u4ntxo0y	111	6	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	111	7	,	,	,
cord-293701-u4ntxo0y	111	8	live	live	JJ
cord-293701-u4ntxo0y	111	9	attenuated	attenuated	JJ
cord-293701-u4ntxo0y	111	10	vaccine	vaccine	NN
cord-293701-u4ntxo0y	111	11	with	with	IN
cord-293701-u4ntxo0y	111	12	four	four	CD
cord-293701-u4ntxo0y	111	13	serotypes	serotype	NNS
cord-293701-u4ntxo0y	111	14	of	of	IN
cord-293701-u4ntxo0y	111	15	DENV	DENV	NNP
cord-293701-u4ntxo0y	111	16	expressed	express	VBD
cord-293701-u4ntxo0y	111	17	on	on	IN
cord-293701-u4ntxo0y	111	18	the	the	DT
cord-293701-u4ntxo0y	111	19	yellow	yellow	JJ
cord-293701-u4ntxo0y	111	20	fever	fever	NN
cord-293701-u4ntxo0y	111	21	backbone	backbone	NN
cord-293701-u4ntxo0y	111	22	63	63	CD
cord-293701-u4ntxo0y	111	23	.	.	.
cord-293701-u4ntxo0y	112	1	In	in	IN
cord-293701-u4ntxo0y	112	2	2018	2018	CD
cord-293701-u4ntxo0y	112	3	,	,	,
cord-293701-u4ntxo0y	112	4	the	the	DT
cord-293701-u4ntxo0y	112	5	FDA	FDA	NNP
cord-293701-u4ntxo0y	112	6	approved	approve	VBD
cord-293701-u4ntxo0y	112	7	the	the	DT
cord-293701-u4ntxo0y	112	8	CYD	CYD	NNP
cord-293701-u4ntxo0y	112	9	-	-	HYPH
cord-293701-u4ntxo0y	112	10	TDV	TDV	NNP
cord-293701-u4ntxo0y	112	11	vaccine	vaccine	NN
cord-293701-u4ntxo0y	112	12	for	for	IN
cord-293701-u4ntxo0y	112	13	preventing	prevent	VBG
cord-293701-u4ntxo0y	112	14	dengue	dengue	NN
cord-293701-u4ntxo0y	112	15	caused	cause	VBN
cord-293701-u4ntxo0y	112	16	by	by	IN
cord-293701-u4ntxo0y	112	17	all	all	DT
cord-293701-u4ntxo0y	112	18	serotypes	serotype	NNS
cord-293701-u4ntxo0y	112	19	(	(	-LRB-
cord-293701-u4ntxo0y	112	20	DENV1-DENV4	DENV1-DENV4	NNP
cord-293701-u4ntxo0y	112	21	)	)	-RRB-
cord-293701-u4ntxo0y	112	22	.	.	.
cord-293701-u4ntxo0y	113	1	However	however	RB
cord-293701-u4ntxo0y	113	2	,	,	,
cord-293701-u4ntxo0y	113	3	administration	administration	NN
cord-293701-u4ntxo0y	113	4	of	of	IN
cord-293701-u4ntxo0y	113	5	this	this	DT
cord-293701-u4ntxo0y	113	6	vaccine	vaccine	NN
cord-293701-u4ntxo0y	113	7	was	be	VBD
cord-293701-u4ntxo0y	113	8	not	not	RB
cord-293701-u4ntxo0y	113	9	permitted	permit	VBN
cord-293701-u4ntxo0y	113	10	in	in	IN
cord-293701-u4ntxo0y	113	11	individuals	individual	NNS
cord-293701-u4ntxo0y	113	12	not	not	RB
cord-293701-u4ntxo0y	113	13	previously	previously	RB
cord-293701-u4ntxo0y	113	14	infected	infect	VBN
cord-293701-u4ntxo0y	113	15	with	with	IN
cord-293701-u4ntxo0y	113	16	DENV	DENV	NNP
cord-293701-u4ntxo0y	113	17	.	.	.
cord-293701-u4ntxo0y	114	1	This	this	DT
cord-293701-u4ntxo0y	114	2	decision	decision	NN
cord-293701-u4ntxo0y	114	3	was	be	VBD
cord-293701-u4ntxo0y	114	4	made	make	VBN
cord-293701-u4ntxo0y	114	5	because	because	IN
cord-293701-u4ntxo0y	114	6	clinical	clinical	JJ
cord-293701-u4ntxo0y	114	7	analyses	analysis	NNS
cord-293701-u4ntxo0y	114	8	revealed	reveal	VBD
cord-293701-u4ntxo0y	114	9	an	an	DT
cord-293701-u4ntxo0y	114	10	excess	excess	JJ
cord-293701-u4ntxo0y	114	11	risk	risk	NN
cord-293701-u4ntxo0y	114	12	of	of	IN
cord-293701-u4ntxo0y	114	13	severe	severe	JJ
cord-293701-u4ntxo0y	114	14	dengue	dengue	NN
cord-293701-u4ntxo0y	114	15	in	in	IN
cord-293701-u4ntxo0y	114	16	seronegative	seronegative	JJ
cord-293701-u4ntxo0y	114	17	vaccinated	vaccinate	VBN
cord-293701-u4ntxo0y	114	18	individuals	individual	NNS
cord-293701-u4ntxo0y	114	19	compared	compare	VBN
cord-293701-u4ntxo0y	114	20	with	with	IN
cord-293701-u4ntxo0y	114	21	seronegative	seronegative	JJ
cord-293701-u4ntxo0y	114	22	non	non	JJ
cord-293701-u4ntxo0y	114	23	-	-	JJ
cord-293701-u4ntxo0y	114	24	vaccinated	vaccinated	JJ
cord-293701-u4ntxo0y	114	25	individuals	individual	NNS
cord-293701-u4ntxo0y	114	26	64	64	CD
cord-293701-u4ntxo0y	114	27	.	.	.
cord-293701-u4ntxo0y	115	1	Because	because	IN
cord-293701-u4ntxo0y	115	2	DENV	DENV	NNP
cord-293701-u4ntxo0y	115	3	can	can	MD
cord-293701-u4ntxo0y	115	4	infect	infect	VB
cord-293701-u4ntxo0y	115	5	FcR	fcr	NN
cord-293701-u4ntxo0y	115	6	-	-	HYPH
cord-293701-u4ntxo0y	115	7	bearing	bear	VBG
cord-293701-u4ntxo0y	115	8	cells	cell	NNS
cord-293701-u4ntxo0y	115	9	whereas	whereas	IN
cord-293701-u4ntxo0y	115	10	SARS	SARS	NNP
cord-293701-u4ntxo0y	115	11	-	-	HYPH
cord-293701-u4ntxo0y	115	12	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	115	13	can	can	MD
cord-293701-u4ntxo0y	115	14	not	not	RB
cord-293701-u4ntxo0y	115	15	,	,	,
cord-293701-u4ntxo0y	115	16	ADE	ADE	NNP
cord-293701-u4ntxo0y	115	17	of	of	IN
cord-293701-u4ntxo0y	115	18	viral	viral	JJ
cord-293701-u4ntxo0y	115	19	infection	infection	NN
cord-293701-u4ntxo0y	115	20	and	and	CC
cord-293701-u4ntxo0y	115	21	disease	disease	NN
cord-293701-u4ntxo0y	115	22	may	may	MD
cord-293701-u4ntxo0y	115	23	be	be	VB
cord-293701-u4ntxo0y	115	24	more	more	RBR
cord-293701-u4ntxo0y	115	25	prominent	prominent	JJ
cord-293701-u4ntxo0y	115	26	in	in	IN
cord-293701-u4ntxo0y	115	27	dengue	dengue	NN
cord-293701-u4ntxo0y	115	28	than	than	IN
cord-293701-u4ntxo0y	115	29	in	in	IN
cord-293701-u4ntxo0y	115	30	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	115	31	,	,	,
cord-293701-u4ntxo0y	115	32	in	in	IN
cord-293701-u4ntxo0y	115	33	which	which	WDT
cord-293701-u4ntxo0y	115	34	it	-PRON-	PRP
cord-293701-u4ntxo0y	115	35	might	may	MD
cord-293701-u4ntxo0y	115	36	be	be	VB
cord-293701-u4ntxo0y	115	37	milder	mild	JJR
cord-293701-u4ntxo0y	115	38	or	or	CC
cord-293701-u4ntxo0y	115	39	even	even	RB
cord-293701-u4ntxo0y	115	40	absent	absent	JJ
cord-293701-u4ntxo0y	115	41	.	.	.
cord-293701-u4ntxo0y	116	1	Besides	besides	RB
cord-293701-u4ntxo0y	116	2	,	,	,
cord-293701-u4ntxo0y	116	3	the	the	DT
cord-293701-u4ntxo0y	116	4	pathophysiology	pathophysiology	NN
cord-293701-u4ntxo0y	116	5	of	of	IN
cord-293701-u4ntxo0y	116	6	dengue	dengue	NN
cord-293701-u4ntxo0y	116	7	is	be	VBZ
cord-293701-u4ntxo0y	116	8	not	not	RB
cord-293701-u4ntxo0y	116	9	comparable	comparable	JJ
cord-293701-u4ntxo0y	116	10	to	to	IN
cord-293701-u4ntxo0y	116	11	that	that	DT
cord-293701-u4ntxo0y	116	12	of	of	IN
cord-293701-u4ntxo0y	116	13	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	116	14	;	;	:
cord-293701-u4ntxo0y	116	15	thus	thus	RB
cord-293701-u4ntxo0y	116	16	,	,	,
cord-293701-u4ntxo0y	116	17	the	the	DT
cord-293701-u4ntxo0y	116	18	VADE	VADE	NNP
cord-293701-u4ntxo0y	116	19	mechanisms	mechanism	NNS
cord-293701-u4ntxo0y	116	20	of	of	IN
cord-293701-u4ntxo0y	116	21	DENV	DENV	NNP
cord-293701-u4ntxo0y	116	22	are	be	VBP
cord-293701-u4ntxo0y	116	23	possibly	possibly	RB
cord-293701-u4ntxo0y	116	24	not	not	RB
cord-293701-u4ntxo0y	116	25	related	relate	VBN
cord-293701-u4ntxo0y	116	26	to	to	IN
cord-293701-u4ntxo0y	116	27	those	those	DT
cord-293701-u4ntxo0y	116	28	in	in	IN
cord-293701-u4ntxo0y	116	29	SARS	SARS	NNP
cord-293701-u4ntxo0y	116	30	-	-	HYPH
cord-293701-u4ntxo0y	116	31	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	116	32	.	.	.
cord-293701-u4ntxo0y	117	1	Still	still	RB
cord-293701-u4ntxo0y	117	2	,	,	,
cord-293701-u4ntxo0y	117	3	valuable	valuable	JJ
cord-293701-u4ntxo0y	117	4	lessons	lesson	NNS
cord-293701-u4ntxo0y	117	5	can	can	MD
cord-293701-u4ntxo0y	117	6	be	be	VB
cord-293701-u4ntxo0y	117	7	learnt	learn	VBN
cord-293701-u4ntxo0y	117	8	from	from	IN
cord-293701-u4ntxo0y	117	9	the	the	DT
cord-293701-u4ntxo0y	117	10	long	long	JJ
cord-293701-u4ntxo0y	117	11	and	and	CC
cord-293701-u4ntxo0y	117	12	challenging	challenging	JJ
cord-293701-u4ntxo0y	117	13	task	task	NN
cord-293701-u4ntxo0y	117	14	of	of	IN
cord-293701-u4ntxo0y	117	15	developing	develop	VBG
cord-293701-u4ntxo0y	117	16	a	a	DT
cord-293701-u4ntxo0y	117	17	dengue	dengue	NN
cord-293701-u4ntxo0y	117	18	vaccine	vaccine	NN
cord-293701-u4ntxo0y	117	19	.	.	.
cord-293701-u4ntxo0y	118	1	First	first	RB
cord-293701-u4ntxo0y	118	2	,	,	,
cord-293701-u4ntxo0y	118	3	aside	aside	RB
cord-293701-u4ntxo0y	118	4	from	from	IN
cord-293701-u4ntxo0y	118	5	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	118	6	activity	activity	NN
cord-293701-u4ntxo0y	118	7	,	,	,
cord-293701-u4ntxo0y	118	8	we	-PRON-	PRP
cord-293701-u4ntxo0y	118	9	know	know	VBP
cord-293701-u4ntxo0y	118	10	that	that	IN
cord-293701-u4ntxo0y	118	11	the	the	DT
cord-293701-u4ntxo0y	118	12	titre	titre	NN
cord-293701-u4ntxo0y	118	13	of	of	IN
cord-293701-u4ntxo0y	118	14	antibodies	antibody	NNS
cord-293701-u4ntxo0y	118	15	induced	induce	VBN
cord-293701-u4ntxo0y	118	16	by	by	IN
cord-293701-u4ntxo0y	118	17	any	any	DT
cord-293701-u4ntxo0y	118	18	vaccine	vaccine	NN
cord-293701-u4ntxo0y	118	19	should	should	MD
cord-293701-u4ntxo0y	118	20	be	be	VB
cord-293701-u4ntxo0y	118	21	fully	fully	RB
cord-293701-u4ntxo0y	118	22	evaluated	evaluate	VBN
cord-293701-u4ntxo0y	118	23	.	.	.
cord-293701-u4ntxo0y	119	1	Low	low	JJ
cord-293701-u4ntxo0y	119	2	titres	titre	NNS
cord-293701-u4ntxo0y	119	3	of	of	IN
cord-293701-u4ntxo0y	119	4	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	119	5	caused	cause	VBD
cord-293701-u4ntxo0y	119	6	ADE	ade	NN
cord-293701-u4ntxo0y	119	7	in	in	IN
cord-293701-u4ntxo0y	119	8	subsequent	subsequent	JJ
cord-293701-u4ntxo0y	119	9	infection	infection	NN
cord-293701-u4ntxo0y	119	10	,	,	,
cord-293701-u4ntxo0y	119	11	instead	instead	RB
cord-293701-u4ntxo0y	119	12	of	of	IN
cord-293701-u4ntxo0y	119	13	providing	provide	VBG
cord-293701-u4ntxo0y	119	14	protection	protection	NN
cord-293701-u4ntxo0y	119	15	,	,	,
cord-293701-u4ntxo0y	119	16	as	as	IN
cord-293701-u4ntxo0y	119	17	observed	observe	VBN
cord-293701-u4ntxo0y	119	18	in	in	IN
cord-293701-u4ntxo0y	119	19	both	both	CC
cord-293701-u4ntxo0y	119	20	DENV	DENV	NNP
cord-293701-u4ntxo0y	119	21	infection	infection	NN
cord-293701-u4ntxo0y	119	22	58	58	CD
cord-293701-u4ntxo0y	119	23	and	and	CC
cord-293701-u4ntxo0y	119	24	RSV	RSV	NNP
cord-293701-u4ntxo0y	119	25	infection	infection	NN
cord-293701-u4ntxo0y	119	26	50	50	CD
cord-293701-u4ntxo0y	119	27	.	.	.
cord-293701-u4ntxo0y	120	1	Second	second	JJ
cord-293701-u4ntxo0y	120	2	,	,	,
cord-293701-u4ntxo0y	120	3	population	population	NN
cord-293701-u4ntxo0y	120	4	genetic	genetic	JJ
cord-293701-u4ntxo0y	120	5	analyses	analysis	NNS
cord-293701-u4ntxo0y	120	6	of	of	IN
cord-293701-u4ntxo0y	120	7	103	103	CD
cord-293701-u4ntxo0y	120	8	SARS	SARS	NNP
cord-293701-u4ntxo0y	120	9	-	-	HYPH
cord-293701-u4ntxo0y	120	10	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	120	11	genomes	genome	NNS
cord-293701-u4ntxo0y	120	12	indicated	indicate	VBD
cord-293701-u4ntxo0y	120	13	that	that	IN
cord-293701-u4ntxo0y	120	14	SARS	SARS	NNP
cord-293701-u4ntxo0y	120	15	-	-	HYPH
cord-293701-u4ntxo0y	120	16	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	120	17	had	have	VBD
cord-293701-u4ntxo0y	120	18	evolved	evolve	VBN
cord-293701-u4ntxo0y	120	19	into	into	IN
cord-293701-u4ntxo0y	120	20	two	two	CD
cord-293701-u4ntxo0y	120	21	major	major	JJ
cord-293701-u4ntxo0y	120	22	types	type	NNS
cord-293701-u4ntxo0y	120	23	(	(	-LRB-
cord-293701-u4ntxo0y	120	24	L	L	NNP
cord-293701-u4ntxo0y	120	25	and	and	CC
cord-293701-u4ntxo0y	120	26	S	S	NNP
cord-293701-u4ntxo0y	120	27	)	)	-RRB-
cord-293701-u4ntxo0y	120	28	based	base	VBN
cord-293701-u4ntxo0y	120	29	on	on	IN
cord-293701-u4ntxo0y	120	30	different	different	JJ
cord-293701-u4ntxo0y	120	31	gene	gene	NN
cord-293701-u4ntxo0y	120	32	mutations	mutation	NNS
cord-293701-u4ntxo0y	120	33	in	in	IN
cord-293701-u4ntxo0y	120	34	ORF1ab	ORF1ab	NNP
cord-293701-u4ntxo0y	120	35	and	and	CC
cord-293701-u4ntxo0y	120	36	ORF8	ORF8	NNP
cord-293701-u4ntxo0y	120	37	(	(	-LRB-
cord-293701-u4ntxo0y	120	38	ref	ref	NN
cord-293701-u4ntxo0y	120	39	.	.	.
cord-293701-u4ntxo0y	120	40	65	65	CD
cord-293701-u4ntxo0y	120	41	)	)	-RRB-
cord-293701-u4ntxo0y	120	42	.	.	.
cord-293701-u4ntxo0y	121	1	A	a	DT
cord-293701-u4ntxo0y	121	2	further	further	JJ
cord-293701-u4ntxo0y	121	3	study	study	NN
cord-293701-u4ntxo0y	121	4	discovered	discover	VBD
cord-293701-u4ntxo0y	121	5	a	a	DT
cord-293701-u4ntxo0y	121	6	382-nucleotide	382-nucleotide	CD
cord-293701-u4ntxo0y	121	7	deletion	deletion	NN
cord-293701-u4ntxo0y	121	8	in	in	IN
cord-293701-u4ntxo0y	121	9	ORF8	ORF8	NNP
cord-293701-u4ntxo0y	121	10	during	during	IN
cord-293701-u4ntxo0y	121	11	the	the	DT
cord-293701-u4ntxo0y	121	12	early	early	JJ
cord-293701-u4ntxo0y	121	13	evolution	evolution	NN
cord-293701-u4ntxo0y	121	14	of	of	IN
cord-293701-u4ntxo0y	121	15	SARS	SARS	NNP
cord-293701-u4ntxo0y	121	16	-	-	HYPH
cord-293701-u4ntxo0y	121	17	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	121	18	(	(	-LRB-
cord-293701-u4ntxo0y	121	19	ref	ref	NN
cord-293701-u4ntxo0y	121	20	.	.	.
cord-293701-u4ntxo0y	122	1	66	66	CD
cord-293701-u4ntxo0y	122	2	)	)	-RRB-
cord-293701-u4ntxo0y	122	3	.	.	.
cord-293701-u4ntxo0y	123	1	The	the	DT
cord-293701-u4ntxo0y	123	2	SARS	SARS	NNP
cord-293701-u4ntxo0y	123	3	-	-	HYPH
cord-293701-u4ntxo0y	123	4	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	123	5	variant	variant	NN
cord-293701-u4ntxo0y	123	6	carrying	carry	VBG
cord-293701-u4ntxo0y	123	7	a	a	DT
cord-293701-u4ntxo0y	123	8	D614	d614	NN
cord-293701-u4ntxo0y	123	9	G	g	NN
cord-293701-u4ntxo0y	123	10	alteration	alteration	NN
cord-293701-u4ntxo0y	123	11	in	in	IN
cord-293701-u4ntxo0y	123	12	the	the	DT
cord-293701-u4ntxo0y	123	13	S	S	NNP
cord-293701-u4ntxo0y	123	14	protein	protein	NN
cord-293701-u4ntxo0y	123	15	became	become	VBD
cord-293701-u4ntxo0y	123	16	the	the	DT
cord-293701-u4ntxo0y	123	17	most	most	RBS
cord-293701-u4ntxo0y	123	18	prevalent	prevalent	JJ
cord-293701-u4ntxo0y	123	19	in	in	IN
cord-293701-u4ntxo0y	123	20	the	the	DT
cord-293701-u4ntxo0y	123	21	global	global	JJ
cord-293701-u4ntxo0y	123	22	pandemic	pandemic	NN
cord-293701-u4ntxo0y	123	23	67	67	CD
cord-293701-u4ntxo0y	123	24	.	.	.
cord-293701-u4ntxo0y	124	1	More	More	JJR
cord-293701-u4ntxo0y	124	2	than	than	IN
cord-293701-u4ntxo0y	124	3	six	six	CD
cord-293701-u4ntxo0y	124	4	human	human	JJ
cord-293701-u4ntxo0y	124	5	coronaviruses	coronaviruse	NNS
cord-293701-u4ntxo0y	124	6	are	be	VBP
cord-293701-u4ntxo0y	124	7	prevalent	prevalent	JJ
cord-293701-u4ntxo0y	124	8	in	in	IN
cord-293701-u4ntxo0y	124	9	human	human	JJ
cord-293701-u4ntxo0y	124	10	populations	population	NNS
cord-293701-u4ntxo0y	124	11	,	,	,
cord-293701-u4ntxo0y	124	12	and	and	CC
cord-293701-u4ntxo0y	124	13	many	many	JJ
cord-293701-u4ntxo0y	124	14	more	more	JJR
cord-293701-u4ntxo0y	124	15	are	be	VBP
cord-293701-u4ntxo0y	124	16	prevalent	prevalent	JJ
cord-293701-u4ntxo0y	124	17	in	in	IN
cord-293701-u4ntxo0y	124	18	wild	wild	JJ
cord-293701-u4ntxo0y	124	19	animal	animal	NN
cord-293701-u4ntxo0y	124	20	species	specie	NNS
cord-293701-u4ntxo0y	124	21	.	.	.
cord-293701-u4ntxo0y	125	1	It	-PRON-	PRP
cord-293701-u4ntxo0y	125	2	is	be	VBZ
cord-293701-u4ntxo0y	125	3	unclear	unclear	JJ
cord-293701-u4ntxo0y	125	4	so	so	RB
cord-293701-u4ntxo0y	125	5	far	far	RB
cord-293701-u4ntxo0y	125	6	whether	whether	IN
cord-293701-u4ntxo0y	125	7	the	the	DT
cord-293701-u4ntxo0y	125	8	continuing	continue	VBG
cord-293701-u4ntxo0y	125	9	mutation	mutation	NN
cord-293701-u4ntxo0y	125	10	and	and	CC
cord-293701-u4ntxo0y	125	11	recombination	recombination	NN
cord-293701-u4ntxo0y	125	12	of	of	IN
cord-293701-u4ntxo0y	125	13	SARS	SARS	NNP
cord-293701-u4ntxo0y	125	14	-	-	HYPH
cord-293701-u4ntxo0y	125	15	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	125	16	could	could	MD
cord-293701-u4ntxo0y	125	17	create	create	VB
cord-293701-u4ntxo0y	125	18	other	other	JJ
cord-293701-u4ntxo0y	125	19	serotypes	serotype	NNS
cord-293701-u4ntxo0y	125	20	of	of	IN
cord-293701-u4ntxo0y	125	21	SARS	SARS	NNP
cord-293701-u4ntxo0y	125	22	-	-	HYPH
cord-293701-u4ntxo0y	125	23	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	125	24	,	,	,
cord-293701-u4ntxo0y	125	25	or	or	CC
cord-293701-u4ntxo0y	125	26	even	even	RB
cord-293701-u4ntxo0y	125	27	another	another	DT
cord-293701-u4ntxo0y	125	28	novel	novel	JJ
cord-293701-u4ntxo0y	125	29	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	125	30	.	.	.
cord-293701-u4ntxo0y	126	1	Therefore	therefore	RB
cord-293701-u4ntxo0y	126	2	,	,	,
cord-293701-u4ntxo0y	126	3	vaccine	vaccine	NN
cord-293701-u4ntxo0y	126	4	candidates	candidate	NNS
cord-293701-u4ntxo0y	126	5	that	that	WDT
cord-293701-u4ntxo0y	126	6	can	can	MD
cord-293701-u4ntxo0y	126	7	provide	provide	VB
cord-293701-u4ntxo0y	126	8	protection	protection	NN
cord-293701-u4ntxo0y	126	9	from	from	IN
cord-293701-u4ntxo0y	126	10	divergent	divergent	JJ
cord-293701-u4ntxo0y	126	11	coronaviruses	coronaviruse	NNS
cord-293701-u4ntxo0y	126	12	would	would	MD
cord-293701-u4ntxo0y	126	13	be	be	VB
cord-293701-u4ntxo0y	126	14	ideal	ideal	JJ
cord-293701-u4ntxo0y	126	15	.	.	.
cord-293701-u4ntxo0y	127	1	Third	third	JJ
cord-293701-u4ntxo0y	127	2	,	,	,
cord-293701-u4ntxo0y	127	3	clinical	clinical	JJ
cord-293701-u4ntxo0y	127	4	data	datum	NNS
cord-293701-u4ntxo0y	127	5	from	from	IN
cord-293701-u4ntxo0y	127	6	a	a	DT
cord-293701-u4ntxo0y	127	7	large	large	JJ
cord-293701-u4ntxo0y	127	8	cohort	cohort	NN
cord-293701-u4ntxo0y	127	9	revealed	reveal	VBD
cord-293701-u4ntxo0y	127	10	that	that	IN
cord-293701-u4ntxo0y	127	11	dengue	dengue	NN
cord-293701-u4ntxo0y	127	12	vaccine	vaccine	NN
cord-293701-u4ntxo0y	127	13	performance	performance	NN
cord-293701-u4ntxo0y	127	14	and	and	CC
cord-293701-u4ntxo0y	127	15	efficacy	efficacy	NN
cord-293701-u4ntxo0y	127	16	could	could	MD
cord-293701-u4ntxo0y	127	17	be	be	VB
cord-293701-u4ntxo0y	127	18	influenced	influence	VBN
cord-293701-u4ntxo0y	127	19	by	by	IN
cord-293701-u4ntxo0y	127	20	the	the	DT
cord-293701-u4ntxo0y	127	21	serotype	serotype	NN
cord-293701-u4ntxo0y	127	22	,	,	,
cord-293701-u4ntxo0y	127	23	baseline	baseline	JJ
cord-293701-u4ntxo0y	127	24	serostatus	serostatus	NN
cord-293701-u4ntxo0y	127	25	and	and	CC
cord-293701-u4ntxo0y	127	26	age	age	NN
cord-293701-u4ntxo0y	127	27	63	63	CD
cord-293701-u4ntxo0y	127	28	,	,	,
cord-293701-u4ntxo0y	127	29	68	68	CD
cord-293701-u4ntxo0y	127	30	.	.	.
cord-293701-u4ntxo0y	128	1	These	these	DT
cord-293701-u4ntxo0y	128	2	results	result	NNS
cord-293701-u4ntxo0y	128	3	constitute	constitute	VBP
cord-293701-u4ntxo0y	128	4	a	a	DT
cord-293701-u4ntxo0y	128	5	warning	warning	NN
cord-293701-u4ntxo0y	128	6	that	that	WDT
cord-293701-u4ntxo0y	128	7	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	128	8	vaccine	vaccine	NN
cord-293701-u4ntxo0y	128	9	candidates	candidate	NNS
cord-293701-u4ntxo0y	128	10	should	should	MD
cord-293701-u4ntxo0y	128	11	be	be	VB
cord-293701-u4ntxo0y	128	12	comprehensively	comprehensively	RB
cord-293701-u4ntxo0y	128	13	assessed	assess	VBN
cord-293701-u4ntxo0y	128	14	in	in	IN
cord-293701-u4ntxo0y	128	15	diverse	diverse	JJ
cord-293701-u4ntxo0y	128	16	animal	animal	NN
cord-293701-u4ntxo0y	128	17	models	model	NNS
cord-293701-u4ntxo0y	128	18	(	(	-LRB-
cord-293701-u4ntxo0y	128	19	that	that	RB
cord-293701-u4ntxo0y	128	20	is	is	RB
cord-293701-u4ntxo0y	128	21	,	,	,
cord-293701-u4ntxo0y	128	22	young	young	JJ
cord-293701-u4ntxo0y	128	23	and	and	CC
cord-293701-u4ntxo0y	128	24	old	old	JJ
cord-293701-u4ntxo0y	128	25	animals	animal	NNS
cord-293701-u4ntxo0y	128	26	,	,	,
cord-293701-u4ntxo0y	128	27	and	and	CC
cord-293701-u4ntxo0y	128	28	male	male	JJ
cord-293701-u4ntxo0y	128	29	and	and	CC
cord-293701-u4ntxo0y	128	30	female	female	JJ
cord-293701-u4ntxo0y	128	31	animals	animal	NNS
cord-293701-u4ntxo0y	128	32	)	)	-RRB-
cord-293701-u4ntxo0y	128	33	to	to	TO
cord-293701-u4ntxo0y	128	34	confirm	confirm	VB
cord-293701-u4ntxo0y	128	35	their	-PRON-	PRP$
cord-293701-u4ntxo0y	128	36	safety	safety	NN
cord-293701-u4ntxo0y	128	37	and	and	CC
cord-293701-u4ntxo0y	128	38	efficacy	efficacy	NN
cord-293701-u4ntxo0y	128	39	and	and	CC
cord-293701-u4ntxo0y	128	40	that	that	IN
cord-293701-u4ntxo0y	128	41	human	human	JJ
cord-293701-u4ntxo0y	128	42	study	study	NN
cord-293701-u4ntxo0y	128	43	participants	participant	NNS
cord-293701-u4ntxo0y	128	44	should	should	MD
cord-293701-u4ntxo0y	128	45	reflect	reflect	VB
cord-293701-u4ntxo0y	128	46	diverse	diverse	JJ
cord-293701-u4ntxo0y	128	47	populations	population	NNS
cord-293701-u4ntxo0y	128	48	.	.	.
cord-293701-u4ntxo0y	129	1	This	this	DT
cord-293701-u4ntxo0y	129	2	is	be	VBZ
cord-293701-u4ntxo0y	129	3	further	far	RBR
cord-293701-u4ntxo0y	129	4	underscored	underscore	VBN
cord-293701-u4ntxo0y	129	5	by	by	IN
cord-293701-u4ntxo0y	129	6	the	the	DT
cord-293701-u4ntxo0y	129	7	different	different	JJ
cord-293701-u4ntxo0y	129	8	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	129	9	severity	severity	NN
cord-293701-u4ntxo0y	129	10	according	accord	VBG
cord-293701-u4ntxo0y	129	11	to	to	IN
cord-293701-u4ntxo0y	129	12	age	age	NN
cord-293701-u4ntxo0y	129	13	and	and	CC
cord-293701-u4ntxo0y	129	14	sex	sex	NN
cord-293701-u4ntxo0y	129	15	,	,	,
cord-293701-u4ntxo0y	129	16	with	with	IN
cord-293701-u4ntxo0y	129	17	older	old	JJR
cord-293701-u4ntxo0y	129	18	and	and	CC
cord-293701-u4ntxo0y	129	19	male	male	JJ
cord-293701-u4ntxo0y	129	20	individuals	individual	NNS
cord-293701-u4ntxo0y	129	21	at	at	IN
cord-293701-u4ntxo0y	129	22	higher	high	JJR
cord-293701-u4ntxo0y	129	23	risk	risk	NN
cord-293701-u4ntxo0y	129	24	of	of	IN
cord-293701-u4ntxo0y	129	25	severe	severe	JJ
cord-293701-u4ntxo0y	129	26	disease	disease	NN
cord-293701-u4ntxo0y	129	27	during	during	IN
cord-293701-u4ntxo0y	129	28	primary	primary	JJ
cord-293701-u4ntxo0y	129	29	infection	infection	NN
cord-293701-u4ntxo0y	129	30	69	69	CD
cord-293701-u4ntxo0y	129	31	.	.	.
cord-293701-u4ntxo0y	130	1	The	the	DT
cord-293701-u4ntxo0y	130	2	genomes	genome	NNS
cord-293701-u4ntxo0y	130	3	of	of	IN
cord-293701-u4ntxo0y	130	4	SARS	SARS	NNP
cord-293701-u4ntxo0y	130	5	-	-	HYPH
cord-293701-u4ntxo0y	130	6	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	130	7	and	and	CC
cord-293701-u4ntxo0y	130	8	SARS	SARS	NNP
cord-293701-u4ntxo0y	130	9	-	-	HYPH
cord-293701-u4ntxo0y	130	10	CoV	CoV	NNP
cord-293701-u4ntxo0y	130	11	share	share	NN
cord-293701-u4ntxo0y	130	12	79.6	79.6	CD
cord-293701-u4ntxo0y	130	13	%	%	NN
cord-293701-u4ntxo0y	130	14	sequence	sequence	NN
cord-293701-u4ntxo0y	130	15	identity	identity	NN
cord-293701-u4ntxo0y	130	16	70	70	CD
cord-293701-u4ntxo0y	130	17	,	,	,
cord-293701-u4ntxo0y	130	18	and	and	CC
cord-293701-u4ntxo0y	130	19	they	-PRON-	PRP
cord-293701-u4ntxo0y	130	20	use	use	VBP
cord-293701-u4ntxo0y	130	21	the	the	DT
cord-293701-u4ntxo0y	130	22	same	same	JJ
cord-293701-u4ntxo0y	130	23	receptor	receptor	NN
cord-293701-u4ntxo0y	130	24	,	,	,
cord-293701-u4ntxo0y	130	25	angiotensin	angiotensin	NN
cord-293701-u4ntxo0y	130	26	-	-	HYPH
cord-293701-u4ntxo0y	130	27	converting	convert	VBG
cord-293701-u4ntxo0y	130	28	enzyme	enzyme	NN
cord-293701-u4ntxo0y	130	29	2	2	CD
cord-293701-u4ntxo0y	130	30	(	(	-LRB-
cord-293701-u4ntxo0y	130	31	ACE2	ACE2	NNP
cord-293701-u4ntxo0y	130	32	)	)	-RRB-
cord-293701-u4ntxo0y	130	33	,	,	,
cord-293701-u4ntxo0y	130	34	to	to	TO
cord-293701-u4ntxo0y	130	35	enter	enter	VB
cord-293701-u4ntxo0y	130	36	cells	cell	NNS
cord-293701-u4ntxo0y	130	37	71	71	CD
cord-293701-u4ntxo0y	130	38	.	.	.
cord-293701-u4ntxo0y	131	1	Therefore	therefore	RB
cord-293701-u4ntxo0y	131	2	,	,	,
cord-293701-u4ntxo0y	131	3	SARS	SARS	NNP
cord-293701-u4ntxo0y	131	4	vaccine	vaccine	NN
cord-293701-u4ntxo0y	131	5	-	-	HYPH
cord-293701-u4ntxo0y	131	6	induced	induce	VBN
cord-293701-u4ntxo0y	131	7	immune	immune	JJ
cord-293701-u4ntxo0y	131	8	responses	response	NNS
cord-293701-u4ntxo0y	131	9	,	,	,
cord-293701-u4ntxo0y	131	10	which	which	WDT
cord-293701-u4ntxo0y	131	11	have	have	VBP
cord-293701-u4ntxo0y	131	12	already	already	RB
cord-293701-u4ntxo0y	131	13	been	be	VBN
cord-293701-u4ntxo0y	131	14	studied	study	VBN
cord-293701-u4ntxo0y	131	15	,	,	,
cord-293701-u4ntxo0y	131	16	would	would	MD
cord-293701-u4ntxo0y	131	17	be	be	VB
cord-293701-u4ntxo0y	131	18	useful	useful	JJ
cord-293701-u4ntxo0y	131	19	in	in	IN
cord-293701-u4ntxo0y	131	20	the	the	DT
cord-293701-u4ntxo0y	131	21	evaluation	evaluation	NN
cord-293701-u4ntxo0y	131	22	of	of	IN
cord-293701-u4ntxo0y	131	23	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	131	24	candidate	candidate	NN
cord-293701-u4ntxo0y	131	25	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	131	26	.	.	.
cord-293701-u4ntxo0y	132	1	In	in	IN
cord-293701-u4ntxo0y	132	2	2003	2003	CD
cord-293701-u4ntxo0y	132	3	,	,	,
cord-293701-u4ntxo0y	132	4	soon	soon	RB
cord-293701-u4ntxo0y	132	5	after	after	IN
cord-293701-u4ntxo0y	132	6	isolation	isolation	NN
cord-293701-u4ntxo0y	132	7	of	of	IN
cord-293701-u4ntxo0y	132	8	SARS	SARS	NNP
cord-293701-u4ntxo0y	132	9	-	-	HYPH
cord-293701-u4ntxo0y	132	10	CoV	CoV	NNP
cord-293701-u4ntxo0y	132	11	viral	viral	JJ
cord-293701-u4ntxo0y	132	12	particles	particle	NNS
cord-293701-u4ntxo0y	132	13	and	and	CC
cord-293701-u4ntxo0y	132	14	release	release	NN
cord-293701-u4ntxo0y	132	15	of	of	IN
cord-293701-u4ntxo0y	132	16	the	the	DT
cord-293701-u4ntxo0y	132	17	viral	viral	JJ
cord-293701-u4ntxo0y	132	18	genome	genome	NN
cord-293701-u4ntxo0y	132	19	sequence	sequence	NN
cord-293701-u4ntxo0y	132	20	,	,	,
cord-293701-u4ntxo0y	132	21	SARS	SARS	NNP
cord-293701-u4ntxo0y	132	22	vaccine	vaccine	NN
cord-293701-u4ntxo0y	132	23	design	design	NN
cord-293701-u4ntxo0y	132	24	began	begin	VBD
cord-293701-u4ntxo0y	132	25	.	.	.
cord-293701-u4ntxo0y	133	1	Similarly	similarly	RB
cord-293701-u4ntxo0y	133	2	to	to	TO
cord-293701-u4ntxo0y	133	3	COVID-19	covid-19	VB
cord-293701-u4ntxo0y	133	4	vaccine	vaccine	NN
cord-293701-u4ntxo0y	133	5	developers	developer	NNS
cord-293701-u4ntxo0y	133	6	,	,	,
cord-293701-u4ntxo0y	133	7	researchers	researcher	NNS
cord-293701-u4ntxo0y	133	8	first	first	RB
cord-293701-u4ntxo0y	133	9	sought	seek	VBD
cord-293701-u4ntxo0y	133	10	SARS	SARS	NNP
cord-293701-u4ntxo0y	133	11	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	133	12	based	base	VBN
cord-293701-u4ntxo0y	133	13	on	on	IN
cord-293701-u4ntxo0y	133	14	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	133	15	virus	virus	NN
cord-293701-u4ntxo0y	133	16	,	,	,
cord-293701-u4ntxo0y	133	17	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	133	18	subunit	subunit	NN
cord-293701-u4ntxo0y	133	19	proteins	protein	NNS
cord-293701-u4ntxo0y	133	20	and	and	CC
cord-293701-u4ntxo0y	133	21	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	133	22	vectors	vector	NNS
cord-293701-u4ntxo0y	133	23	.	.	.
cord-293701-u4ntxo0y	134	1	Also	also	RB
cord-293701-u4ntxo0y	134	2	in	in	IN
cord-293701-u4ntxo0y	134	3	2003	2003	CD
cord-293701-u4ntxo0y	134	4	,	,	,
cord-293701-u4ntxo0y	134	5	an	an	DT
cord-293701-u4ntxo0y	134	6	Ad5	ad5	CD
cord-293701-u4ntxo0y	134	7	vector	vector	NN
cord-293701-u4ntxo0y	134	8	-	-	HYPH
cord-293701-u4ntxo0y	134	9	based	base	VBN
cord-293701-u4ntxo0y	134	10	vaccine	vaccine	NN
cord-293701-u4ntxo0y	134	11	that	that	WDT
cord-293701-u4ntxo0y	134	12	expresses	express	VBZ
cord-293701-u4ntxo0y	134	13	the	the	DT
cord-293701-u4ntxo0y	134	14	SARS	SARS	NNP
cord-293701-u4ntxo0y	134	15	-	-	HYPH
cord-293701-u4ntxo0y	134	16	CoV	CoV	NNP
cord-293701-u4ntxo0y	134	17	S1	S1	NNP
cord-293701-u4ntxo0y	134	18	protein	protein	NN
cord-293701-u4ntxo0y	134	19	,	,	,
cord-293701-u4ntxo0y	134	20	membrane	membrane	NN
cord-293701-u4ntxo0y	134	21	(	(	-LRB-
cord-293701-u4ntxo0y	134	22	M	M	NNP
cord-293701-u4ntxo0y	134	23	)	)	-RRB-
cord-293701-u4ntxo0y	134	24	protein	protein	NN
cord-293701-u4ntxo0y	134	25	and	and	CC
cord-293701-u4ntxo0y	134	26	nucleocapsid	nucleocapsid	NN
cord-293701-u4ntxo0y	134	27	(	(	-LRB-
cord-293701-u4ntxo0y	134	28	N	N	NNP
cord-293701-u4ntxo0y	134	29	)	)	-RRB-
cord-293701-u4ntxo0y	134	30	protein	protein	NN
cord-293701-u4ntxo0y	134	31	was	be	VBD
cord-293701-u4ntxo0y	134	32	tested	test	VBN
cord-293701-u4ntxo0y	134	33	in	in	IN
cord-293701-u4ntxo0y	134	34	rhesus	rhesu	NNS
cord-293701-u4ntxo0y	134	35	macaques	macaque	NNS
cord-293701-u4ntxo0y	134	36	.	.	.
cord-293701-u4ntxo0y	135	1	These	these	DT
cord-293701-u4ntxo0y	135	2	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	135	3	induced	induce	VBN
cord-293701-u4ntxo0y	135	4	SARS	SARS	NNP
cord-293701-u4ntxo0y	135	5	-	-	HYPH
cord-293701-u4ntxo0y	135	6	CoV	cov	NN
cord-293701-u4ntxo0y	135	7	-	-	HYPH
cord-293701-u4ntxo0y	135	8	specific	specific	JJ
cord-293701-u4ntxo0y	135	9	T	t	NN
cord-293701-u4ntxo0y	135	10	cell	cell	NN
cord-293701-u4ntxo0y	135	11	and	and	CC
cord-293701-u4ntxo0y	135	12	NAb	nab	VBP
cord-293701-u4ntxo0y	135	13	responses	response	NNS
cord-293701-u4ntxo0y	135	14	72	72	CD
cord-293701-u4ntxo0y	135	15	.	.	.
cord-293701-u4ntxo0y	136	1	Ad5-SARS	Ad5-SARS	NNP
cord-293701-u4ntxo0y	136	2	-	-	HYPH
cord-293701-u4ntxo0y	136	3	CoV	CoV	NNP
cord-293701-u4ntxo0y	136	4	-	-	HYPH
cord-293701-u4ntxo0y	136	5	S	S	NNP
cord-293701-u4ntxo0y	136	6	led	lead	VBD
cord-293701-u4ntxo0y	136	7	to	to	IN
cord-293701-u4ntxo0y	136	8	a	a	DT
cord-293701-u4ntxo0y	136	9	substantial	substantial	JJ
cord-293701-u4ntxo0y	136	10	reduction	reduction	NN
cord-293701-u4ntxo0y	136	11	in	in	IN
cord-293701-u4ntxo0y	136	12	viral	viral	JJ
cord-293701-u4ntxo0y	136	13	load	load	NN
cord-293701-u4ntxo0y	136	14	and	and	CC
cord-293701-u4ntxo0y	136	15	prevented	prevent	VBD
cord-293701-u4ntxo0y	136	16	severe	severe	JJ
cord-293701-u4ntxo0y	136	17	pneumonia	pneumonia	NN
cord-293701-u4ntxo0y	136	18	in	in	IN
cord-293701-u4ntxo0y	136	19	ferrets	ferret	NNS
cord-293701-u4ntxo0y	136	20	73	73	CD
cord-293701-u4ntxo0y	136	21	.	.	.
cord-293701-u4ntxo0y	137	1	A	a	DT
cord-293701-u4ntxo0y	137	2	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	137	3	modified	modify	VBN
cord-293701-u4ntxo0y	137	4	vaccinia	vaccinia	NN
cord-293701-u4ntxo0y	137	5	virus	virus	NN
cord-293701-u4ntxo0y	137	6	Ankara	Ankara	NNP
cord-293701-u4ntxo0y	137	7	vector	vector	NN
cord-293701-u4ntxo0y	137	8	expressing	express	VBG
cord-293701-u4ntxo0y	138	1	SARS	SARS	NNP
cord-293701-u4ntxo0y	138	2	-	-	HYPH
cord-293701-u4ntxo0y	138	3	CoV	CoV	NNP
cord-293701-u4ntxo0y	138	4	S	S	NNP
cord-293701-u4ntxo0y	138	5	protein	protein	NN
cord-293701-u4ntxo0y	138	6	elicited	elicit	VBD
cord-293701-u4ntxo0y	138	7	a	a	DT
cord-293701-u4ntxo0y	138	8	rapid	rapid	JJ
cord-293701-u4ntxo0y	138	9	and	and	CC
cord-293701-u4ntxo0y	138	10	vigorous	vigorous	JJ
cord-293701-u4ntxo0y	138	11	NAb	NAb	NNS
cord-293701-u4ntxo0y	138	12	response	response	NN
cord-293701-u4ntxo0y	138	13	in	in	IN
cord-293701-u4ntxo0y	138	14	ferrets	ferret	NNS
cord-293701-u4ntxo0y	138	15	;	;	:
cord-293701-u4ntxo0y	138	16	however	however	RB
cord-293701-u4ntxo0y	138	17	,	,	,
cord-293701-u4ntxo0y	138	18	a	a	DT
cord-293701-u4ntxo0y	138	19	strong	strong	JJ
cord-293701-u4ntxo0y	138	20	inflammatory	inflammatory	JJ
cord-293701-u4ntxo0y	138	21	response	response	NN
cord-293701-u4ntxo0y	138	22	in	in	IN
cord-293701-u4ntxo0y	138	23	the	the	DT
cord-293701-u4ntxo0y	138	24	liver	liver	NN
cord-293701-u4ntxo0y	138	25	of	of	IN
cord-293701-u4ntxo0y	138	26	immunized	immunize	VBN
cord-293701-u4ntxo0y	138	27	ferrets	ferret	NNS
cord-293701-u4ntxo0y	138	28	occurred	occur	VBD
cord-293701-u4ntxo0y	138	29	after	after	IN
cord-293701-u4ntxo0y	138	30	challenge	challenge	NN
cord-293701-u4ntxo0y	138	31	with	with	IN
cord-293701-u4ntxo0y	138	32	SARS	SARS	NNP
cord-293701-u4ntxo0y	138	33	-	-	HYPH
cord-293701-u4ntxo0y	138	34	CoV	CoV	NNP
cord-293701-u4ntxo0y	138	35	74	74	CD
cord-293701-u4ntxo0y	138	36	,	,	,
cord-293701-u4ntxo0y	138	37	75	75	CD
cord-293701-u4ntxo0y	138	38	.	.	.
cord-293701-u4ntxo0y	139	1	More	More	JJR
cord-293701-u4ntxo0y	139	2	studies	study	NNS
cord-293701-u4ntxo0y	139	3	then	then	RB
cord-293701-u4ntxo0y	139	4	demonstrated	demonstrate	VBD
cord-293701-u4ntxo0y	139	5	that	that	IN
cord-293701-u4ntxo0y	139	6	SARS	SARS	NNP
cord-293701-u4ntxo0y	139	7	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	139	8	,	,	,
cord-293701-u4ntxo0y	139	9	based	base	VBN
cord-293701-u4ntxo0y	139	10	on	on	IN
cord-293701-u4ntxo0y	139	11	either	either	CC
cord-293701-u4ntxo0y	139	12	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	139	13	virus	virus	NN
cord-293701-u4ntxo0y	139	14	or	or	CC
cord-293701-u4ntxo0y	139	15	a	a	DT
cord-293701-u4ntxo0y	139	16	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	139	17	vector	vector	NN
cord-293701-u4ntxo0y	139	18	,	,	,
cord-293701-u4ntxo0y	139	19	could	could	MD
cord-293701-u4ntxo0y	139	20	induce	induce	VB
cord-293701-u4ntxo0y	139	21	eosinophils	eosinophil	NNS
cord-293701-u4ntxo0y	139	22	and	and	CC
cord-293701-u4ntxo0y	139	23	T	t	NN
cord-293701-u4ntxo0y	139	24	H	h	NN
cord-293701-u4ntxo0y	139	25	2	2	CD
cord-293701-u4ntxo0y	139	26	cell	cell	NN
cord-293701-u4ntxo0y	139	27	-	-	HYPH
cord-293701-u4ntxo0y	139	28	skewed	skew	VBN
cord-293701-u4ntxo0y	139	29	immune	immune	JJ
cord-293701-u4ntxo0y	139	30	responses	response	NNS
cord-293701-u4ntxo0y	139	31	on	on	IN
cord-293701-u4ntxo0y	139	32	subsequent	subsequent	JJ
cord-293701-u4ntxo0y	139	33	challenge	challenge	NN
cord-293701-u4ntxo0y	139	34	with	with	IN
cord-293701-u4ntxo0y	139	35	SARS	SARS	NNP
cord-293701-u4ntxo0y	139	36	-	-	HYPH
cord-293701-u4ntxo0y	139	37	CoV	CoV	NNP
cord-293701-u4ntxo0y	139	38	in	in	IN
cord-293701-u4ntxo0y	139	39	a	a	DT
cord-293701-u4ntxo0y	139	40	mouse	mouse	NN
cord-293701-u4ntxo0y	139	41	model	model	NN
cord-293701-u4ntxo0y	139	42	[	[	-LRB-
cord-293701-u4ntxo0y	139	43	76	76	CD
cord-293701-u4ntxo0y	139	44	]	]	-RRB-
cord-293701-u4ntxo0y	139	45	[	[	-LRB-
cord-293701-u4ntxo0y	139	46	77	77	CD
cord-293701-u4ntxo0y	139	47	]	]	-RRB-
cord-293701-u4ntxo0y	139	48	[	[	-LRB-
cord-293701-u4ntxo0y	139	49	78	78	CD
cord-293701-u4ntxo0y	139	50	]	]	-RRB-
cord-293701-u4ntxo0y	139	51	,	,	,
cord-293701-u4ntxo0y	139	52	which	which	WDT
cord-293701-u4ntxo0y	139	53	is	be	VBZ
cord-293701-u4ntxo0y	139	54	reminiscent	reminiscent	JJ
cord-293701-u4ntxo0y	139	55	of	of	IN
cord-293701-u4ntxo0y	139	56	RSV	RSV	NNP
cord-293701-u4ntxo0y	139	57	vaccine	vaccine	NN
cord-293701-u4ntxo0y	139	58	-	-	HYPH
cord-293701-u4ntxo0y	139	59	induced	induce	VBN
cord-293701-u4ntxo0y	139	60	ERD	ERD	NNP
cord-293701-u4ntxo0y	139	61	in	in	IN
cord-293701-u4ntxo0y	139	62	infants	infant	NNS
cord-293701-u4ntxo0y	139	63	.	.	.
cord-293701-u4ntxo0y	140	1	Similarly	similarly	RB
cord-293701-u4ntxo0y	140	2	,	,	,
cord-293701-u4ntxo0y	140	3	an	an	DT
cord-293701-u4ntxo0y	140	4	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	140	5	SARS	SARS	NNP
cord-293701-u4ntxo0y	140	6	-	-	HYPH
cord-293701-u4ntxo0y	140	7	CoV	CoV	NNP
cord-293701-u4ntxo0y	140	8	vaccine	vaccine	NN
cord-293701-u4ntxo0y	140	9	and	and	CC
cord-293701-u4ntxo0y	140	10	a	a	DT
cord-293701-u4ntxo0y	140	11	SARS	SARS	NNP
cord-293701-u4ntxo0y	140	12	-	-	HYPH
cord-293701-u4ntxo0y	140	13	CoV	CoV	NNP
cord-293701-u4ntxo0y	140	14	S	S	NNP
cord-293701-u4ntxo0y	140	15	protein	protein	NN
cord-293701-u4ntxo0y	140	16	-	-	HYPH
cord-293701-u4ntxo0y	140	17	derived	derive	VBN
cord-293701-u4ntxo0y	140	18	peptide	peptide	JJ
cord-293701-u4ntxo0y	140	19	vaccine	vaccine	NN
cord-293701-u4ntxo0y	140	20	both	both	DT
cord-293701-u4ntxo0y	140	21	induced	induce	VBN
cord-293701-u4ntxo0y	140	22	severer	severe	JJR
cord-293701-u4ntxo0y	140	23	lung	lung	NN
cord-293701-u4ntxo0y	140	24	damage	damage	NN
cord-293701-u4ntxo0y	140	25	in	in	IN
cord-293701-u4ntxo0y	140	26	rhesus	rhesus	NN
cord-293701-u4ntxo0y	140	27	macaques	macaque	NNS
cord-293701-u4ntxo0y	140	28	after	after	IN
cord-293701-u4ntxo0y	140	29	SARS	SARS	NNP
cord-293701-u4ntxo0y	140	30	-	-	HYPH
cord-293701-u4ntxo0y	140	31	CoV	CoV	NNP
cord-293701-u4ntxo0y	140	32	challenge	challenge	NN
cord-293701-u4ntxo0y	140	33	79	79	CD
cord-293701-u4ntxo0y	140	34	.	.	.
cord-293701-u4ntxo0y	141	1	A	a	DT
cord-293701-u4ntxo0y	141	2	DNA	dna	NN
cord-293701-u4ntxo0y	141	3	vaccine	vaccine	NN
cord-293701-u4ntxo0y	141	4	encoding	encode	VBG
cord-293701-u4ntxo0y	141	5	the	the	DT
cord-293701-u4ntxo0y	141	6	S	S	NNP
cord-293701-u4ntxo0y	141	7	protein	protein	NN
cord-293701-u4ntxo0y	141	8	of	of	IN
cord-293701-u4ntxo0y	141	9	SARS	SARS	NNP
cord-293701-u4ntxo0y	141	10	-	-	HYPH
cord-293701-u4ntxo0y	141	11	CoV	CoV	NNP
cord-293701-u4ntxo0y	142	1	induced	induce	VBN
cord-293701-u4ntxo0y	142	2	CD4	CD4	NNP
cord-293701-u4ntxo0y	142	3	+	+	CC
cord-293701-u4ntxo0y	142	4	and	and	CC
cord-293701-u4ntxo0y	142	5	CD8	CD8	NNP
cord-293701-u4ntxo0y	142	6	+	+	CC
cord-293701-u4ntxo0y	142	7	T	T	NNP
cord-293701-u4ntxo0y	142	8	cell	cell	NN
cord-293701-u4ntxo0y	142	9	and	and	CC
cord-293701-u4ntxo0y	142	10	NAb	nab	VBP
cord-293701-u4ntxo0y	142	11	responses	response	NNS
cord-293701-u4ntxo0y	142	12	in	in	IN
cord-293701-u4ntxo0y	142	13	a	a	DT
cord-293701-u4ntxo0y	142	14	mouse	mouse	NN
cord-293701-u4ntxo0y	142	15	model	model	NN
cord-293701-u4ntxo0y	142	16	and	and	CC
cord-293701-u4ntxo0y	142	17	in	in	IN
cord-293701-u4ntxo0y	142	18	a	a	DT
cord-293701-u4ntxo0y	142	19	phase	phase	NN
cord-293701-u4ntxo0y	142	20	I	-PRON-	PRP
cord-293701-u4ntxo0y	142	21	clinical	clinical	JJ
cord-293701-u4ntxo0y	142	22	trial	trial	NN
cord-293701-u4ntxo0y	142	23	80	80	CD
cord-293701-u4ntxo0y	142	24	,	,	,
cord-293701-u4ntxo0y	142	25	81	81	CD
cord-293701-u4ntxo0y	142	26	.	.	.
cord-293701-u4ntxo0y	143	1	ADE	ADE	NNP
cord-293701-u4ntxo0y	143	2	was	be	VBD
cord-293701-u4ntxo0y	143	3	also	also	RB
cord-293701-u4ntxo0y	143	4	observed	observe	VBN
cord-293701-u4ntxo0y	143	5	in	in	IN
cord-293701-u4ntxo0y	143	6	SARS	SARS	NNP
cord-293701-u4ntxo0y	143	7	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	143	8	.	.	.
cord-293701-u4ntxo0y	144	1	A	a	DT
cord-293701-u4ntxo0y	144	2	SARS	SARS	NNP
cord-293701-u4ntxo0y	144	3	vaccine	vaccine	NN
cord-293701-u4ntxo0y	144	4	based	base	VBN
cord-293701-u4ntxo0y	144	5	on	on	IN
cord-293701-u4ntxo0y	144	6	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	144	7	SARS	SARS	NNP
cord-293701-u4ntxo0y	144	8	-	-	HYPH
cord-293701-u4ntxo0y	144	9	CoV	CoV	NNP
cord-293701-u4ntxo0y	144	10	S	S	NNP
cord-293701-u4ntxo0y	144	11	protein	protein	NN
cord-293701-u4ntxo0y	144	12	protected	protect	VBD
cord-293701-u4ntxo0y	144	13	hamsters	hamster	NNS
cord-293701-u4ntxo0y	144	14	from	from	IN
cord-293701-u4ntxo0y	144	15	SARS	SARS	NNP
cord-293701-u4ntxo0y	144	16	-	-	HYPH
cord-293701-u4ntxo0y	144	17	CoV	CoV	NNP
cord-293701-u4ntxo0y	144	18	infection	infection	NN
cord-293701-u4ntxo0y	144	19	;	;	:
cord-293701-u4ntxo0y	144	20	however	however	RB
cord-293701-u4ntxo0y	144	21	,	,	,
cord-293701-u4ntxo0y	144	22	the	the	DT
cord-293701-u4ntxo0y	144	23	S	S	NNP
cord-293701-u4ntxo0y	144	24	protein	protein	NN
cord-293701-u4ntxo0y	144	25	-	-	HYPH
cord-293701-u4ntxo0y	144	26	specific	specific	JJ
cord-293701-u4ntxo0y	144	27	antibodies	antibody	NNS
cord-293701-u4ntxo0y	144	28	could	could	MD
cord-293701-u4ntxo0y	144	29	mediate	mediate	VB
cord-293701-u4ntxo0y	144	30	FcR	fcr	NN
cord-293701-u4ntxo0y	144	31	-	-	HYPH
cord-293701-u4ntxo0y	144	32	dependent	dependent	JJ
cord-293701-u4ntxo0y	144	33	entry	entry	NN
cord-293701-u4ntxo0y	144	34	into	into	IN
cord-293701-u4ntxo0y	144	35	B	b	NN
cord-293701-u4ntxo0y	144	36	cells	cell	NNS
cord-293701-u4ntxo0y	144	37	in	in	IN
cord-293701-u4ntxo0y	144	38	vitro	vitro	NNP
cord-293701-u4ntxo0y	144	39	82	82	CD
cord-293701-u4ntxo0y	144	40	,	,	,
cord-293701-u4ntxo0y	144	41	83	83	CD
cord-293701-u4ntxo0y	144	42	.	.	.
cord-293701-u4ntxo0y	145	1	Furthermore	furthermore	RB
cord-293701-u4ntxo0y	145	2	,	,	,
cord-293701-u4ntxo0y	145	3	diluted	dilute	VBN
cord-293701-u4ntxo0y	145	4	SARS	SARS	NNP
cord-293701-u4ntxo0y	145	5	-	-	HYPH
cord-293701-u4ntxo0y	145	6	CoV	CoV	NNP
cord-293701-u4ntxo0y	145	7	S	S	NNP
cord-293701-u4ntxo0y	145	8	protein	protein	NN
cord-293701-u4ntxo0y	145	9	-	-	HYPH
cord-293701-u4ntxo0y	145	10	specific	specific	JJ
cord-293701-u4ntxo0y	145	11	antibodies	antibody	NNS
cord-293701-u4ntxo0y	145	12	resulted	result	VBD
cord-293701-u4ntxo0y	145	13	in	in	IN
cord-293701-u4ntxo0y	145	14	increased	increase	VBN
cord-293701-u4ntxo0y	145	15	virus	virus	NN
cord-293701-u4ntxo0y	145	16	infectivity	infectivity	NN
cord-293701-u4ntxo0y	145	17	and	and	CC
cord-293701-u4ntxo0y	145	18	cytopathic	cytopathic	JJ
cord-293701-u4ntxo0y	145	19	effect	effect	NN
cord-293701-u4ntxo0y	145	20	in	in	IN
cord-293701-u4ntxo0y	145	21	an	an	DT
cord-293701-u4ntxo0y	145	22	HL	HL	NNP
cord-293701-u4ntxo0y	145	23	-	-	HYPH
cord-293701-u4ntxo0y	145	24	CZ	CZ	NNP
cord-293701-u4ntxo0y	145	25	human	human	JJ
cord-293701-u4ntxo0y	145	26	promonocyte	promonocyte	NN
cord-293701-u4ntxo0y	145	27	cell	cell	NN
cord-293701-u4ntxo0y	145	28	line	line	NN
cord-293701-u4ntxo0y	145	29	84	84	CD
cord-293701-u4ntxo0y	145	30	.	.	.
cord-293701-u4ntxo0y	146	1	Except	except	IN
cord-293701-u4ntxo0y	146	2	for	for	IN
cord-293701-u4ntxo0y	146	3	the	the	DT
cord-293701-u4ntxo0y	146	4	ADE	ade	NN
cord-293701-u4ntxo0y	146	5	,	,	,
cord-293701-u4ntxo0y	146	6	antibody	antibody	NN
cord-293701-u4ntxo0y	146	7	-	-	HYPH
cord-293701-u4ntxo0y	146	8	mediated	mediate	VBN
cord-293701-u4ntxo0y	146	9	unbalanced	unbalanced	JJ
cord-293701-u4ntxo0y	146	10	macrophage	macrophage	NN
cord-293701-u4ntxo0y	146	11	activation	activation	NN
cord-293701-u4ntxo0y	146	12	has	have	VBZ
cord-293701-u4ntxo0y	146	13	been	be	VBN
cord-293701-u4ntxo0y	146	14	reported	report	VBN
cord-293701-u4ntxo0y	146	15	to	to	TO
cord-293701-u4ntxo0y	146	16	be	be	VB
cord-293701-u4ntxo0y	146	17	associated	associate	VBN
cord-293701-u4ntxo0y	146	18	with	with	IN
cord-293701-u4ntxo0y	146	19	obvious	obvious	JJ
cord-293701-u4ntxo0y	146	20	lung	lung	NN
cord-293701-u4ntxo0y	146	21	injury	injury	NN
cord-293701-u4ntxo0y	146	22	in	in	IN
cord-293701-u4ntxo0y	146	23	vivo	vivo	NNP
cord-293701-u4ntxo0y	146	24	.	.	.
cord-293701-u4ntxo0y	147	1	Passive	passive	JJ
cord-293701-u4ntxo0y	147	2	transfer	transfer	NN
cord-293701-u4ntxo0y	147	3	of	of	IN
cord-293701-u4ntxo0y	147	4	anti	anti	JJ
cord-293701-u4ntxo0y	147	5	-	-	JJ
cord-293701-u4ntxo0y	147	6	S	s	JJ
cord-293701-u4ntxo0y	147	7	IgG	igg	NN
cord-293701-u4ntxo0y	147	8	abrogated	abrogate	VBD
cord-293701-u4ntxo0y	147	9	wound	wound	NN
cord-293701-u4ntxo0y	147	10	-	-	HYPH
cord-293701-u4ntxo0y	147	11	healing	heal	VBG
cord-293701-u4ntxo0y	147	12	responses	response	NNS
cord-293701-u4ntxo0y	147	13	and	and	CC
cord-293701-u4ntxo0y	147	14	promoted	promote	VBD
cord-293701-u4ntxo0y	147	15	proinflammatory	proinflammatory	JJ
cord-293701-u4ntxo0y	147	16	monocyte	monocyte	NNP
cord-293701-u4ntxo0y	147	17	and	and	CC
cord-293701-u4ntxo0y	147	18	macrophage	macrophage	NN
cord-293701-u4ntxo0y	147	19	recruitment	recruitment	NN
cord-293701-u4ntxo0y	147	20	and	and	CC
cord-293701-u4ntxo0y	147	21	accumulation	accumulation	NN
cord-293701-u4ntxo0y	147	22	in	in	IN
cord-293701-u4ntxo0y	147	23	the	the	DT
cord-293701-u4ntxo0y	147	24	lungs	lung	NNS
cord-293701-u4ntxo0y	147	25	of	of	IN
cord-293701-u4ntxo0y	147	26	macaques	macaque	NNS
cord-293701-u4ntxo0y	147	27	after	after	IN
cord-293701-u4ntxo0y	147	28	viral	viral	JJ
cord-293701-u4ntxo0y	147	29	challenge	challenge	NN
cord-293701-u4ntxo0y	147	30	,	,	,
cord-293701-u4ntxo0y	147	31	indicating	indicate	VBG
cord-293701-u4ntxo0y	147	32	that	that	IN
cord-293701-u4ntxo0y	147	33	SARS	SARS	NNP
cord-293701-u4ntxo0y	147	34	-	-	HYPH
cord-293701-u4ntxo0y	147	35	CoV	CoV	NNP
cord-293701-u4ntxo0y	147	36	S	S	NNP
cord-293701-u4ntxo0y	147	37	protein	protein	NN
cord-293701-u4ntxo0y	147	38	-	-	HYPH
cord-293701-u4ntxo0y	147	39	specific	specific	JJ
cord-293701-u4ntxo0y	147	40	antibodies	antibody	NNS
cord-293701-u4ntxo0y	147	41	could	could	MD
cord-293701-u4ntxo0y	147	42	elicit	elicit	VB
cord-293701-u4ntxo0y	147	43	pathogenic	pathogenic	JJ
cord-293701-u4ntxo0y	147	44	immune	immune	JJ
cord-293701-u4ntxo0y	147	45	responses	response	NNS
cord-293701-u4ntxo0y	147	46	,	,	,
cord-293701-u4ntxo0y	147	47	as	as	RB
cord-293701-u4ntxo0y	147	48	well	well	RB
cord-293701-u4ntxo0y	147	49	as	as	IN
cord-293701-u4ntxo0y	147	50	enhance	enhance	VB
cord-293701-u4ntxo0y	147	51	disease	disease	NN
cord-293701-u4ntxo0y	147	52	severity	severity	NN
cord-293701-u4ntxo0y	147	53	after	after	IN
cord-293701-u4ntxo0y	147	54	SARS	SARS	NNP
cord-293701-u4ntxo0y	147	55	-	-	HYPH
cord-293701-u4ntxo0y	147	56	CoV	CoV	NNP
cord-293701-u4ntxo0y	147	57	infection	infection	NN
cord-293701-u4ntxo0y	147	58	24	24	CD
cord-293701-u4ntxo0y	147	59	.	.	.
cord-293701-u4ntxo0y	148	1	Notably	notably	RB
cord-293701-u4ntxo0y	148	2	,	,	,
cord-293701-u4ntxo0y	148	3	the	the	DT
cord-293701-u4ntxo0y	148	4	evidence	evidence	NN
cord-293701-u4ntxo0y	148	5	for	for	IN
cord-293701-u4ntxo0y	148	6	anti	anti	JJ
cord-293701-u4ntxo0y	148	7	-	-	JJ
cord-293701-u4ntxo0y	148	8	S	s	JJ
cord-293701-u4ntxo0y	148	9	IgG	igg	NN
cord-293701-u4ntxo0y	148	10	-	-	HYPH
cord-293701-u4ntxo0y	148	11	mediated	mediate	VBN
cord-293701-u4ntxo0y	148	12	ADE	ADE	NNP
cord-293701-u4ntxo0y	148	13	was	be	VBD
cord-293701-u4ntxo0y	148	14	observed	observe	VBN
cord-293701-u4ntxo0y	148	15	only	only	RB
cord-293701-u4ntxo0y	148	16	in	in	IN
cord-293701-u4ntxo0y	148	17	vitro	vitro	FW
cord-293701-u4ntxo0y	148	18	.	.	.
cord-293701-u4ntxo0y	149	1	Therefore	therefore	RB
cord-293701-u4ntxo0y	149	2	,	,	,
cord-293701-u4ntxo0y	149	3	ADE	ADE	NNP
cord-293701-u4ntxo0y	149	4	seems	seem	VBZ
cord-293701-u4ntxo0y	149	5	a	a	DT
cord-293701-u4ntxo0y	149	6	less	less	RBR
cord-293701-u4ntxo0y	149	7	critical	critical	JJ
cord-293701-u4ntxo0y	149	8	issue	issue	NN
cord-293701-u4ntxo0y	149	9	than	than	IN
cord-293701-u4ntxo0y	149	10	other	other	JJ
cord-293701-u4ntxo0y	149	11	antibody	antibody	NN
cord-293701-u4ntxo0y	149	12	-	-	:
cord-293701-u4ntxo0y	149	13	and	and	CC
cord-293701-u4ntxo0y	149	14	T	T	NNP
cord-293701-u4ntxo0y	149	15	H	h	NN
cord-293701-u4ntxo0y	149	16	2	2	CD
cord-293701-u4ntxo0y	149	17	cell	cell	NN
cord-293701-u4ntxo0y	149	18	-	-	HYPH
cord-293701-u4ntxo0y	149	19	mediated	mediate	VBN
cord-293701-u4ntxo0y	149	20	immunopathology	immunopathology	NN
cord-293701-u4ntxo0y	149	21	in	in	IN
cord-293701-u4ntxo0y	149	22	vivo	vivo	NN
cord-293701-u4ntxo0y	149	23	.	.	.
cord-293701-u4ntxo0y	150	1	MERS	MERS	NNP
cord-293701-u4ntxo0y	150	2	-	-	HYPH
cord-293701-u4ntxo0y	150	3	CoV	CoV	NNP
cord-293701-u4ntxo0y	150	4	belongs	belong	VBZ
cord-293701-u4ntxo0y	150	5	to	to	IN
cord-293701-u4ntxo0y	150	6	the	the	DT
cord-293701-u4ntxo0y	150	7	genus	genus	NN
cord-293701-u4ntxo0y	150	8	Betacoronavirus	Betacoronavirus	NNP
cord-293701-u4ntxo0y	150	9	,	,	,
cord-293701-u4ntxo0y	150	10	which	which	WDT
cord-293701-u4ntxo0y	150	11	also	also	RB
cord-293701-u4ntxo0y	150	12	includes	include	VBZ
cord-293701-u4ntxo0y	150	13	SARS	SARS	NNP
cord-293701-u4ntxo0y	150	14	-	-	HYPH
cord-293701-u4ntxo0y	150	15	CoV	CoV	NNP
cord-293701-u4ntxo0y	150	16	and	and	CC
cord-293701-u4ntxo0y	150	17	SARS	SARS	NNP
cord-293701-u4ntxo0y	150	18	-	-	HYPH
cord-293701-u4ntxo0y	150	19	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	150	20	.	.	.
cord-293701-u4ntxo0y	151	1	Since	since	IN
cord-293701-u4ntxo0y	151	2	the	the	DT
cord-293701-u4ntxo0y	151	3	virus	virus	NN
cord-293701-u4ntxo0y	151	4	was	be	VBD
cord-293701-u4ntxo0y	151	5	first	first	RB
cord-293701-u4ntxo0y	151	6	identified	identify	VBN
cord-293701-u4ntxo0y	151	7	in	in	IN
cord-293701-u4ntxo0y	151	8	Saudi	Saudi	NNP
cord-293701-u4ntxo0y	151	9	Arabia	Arabia	NNP
cord-293701-u4ntxo0y	151	10	in	in	IN
cord-293701-u4ntxo0y	151	11	2012	2012	CD
cord-293701-u4ntxo0y	151	12	,	,	,
cord-293701-u4ntxo0y	151	13	many	many	JJ
cord-293701-u4ntxo0y	151	14	vaccine	vaccine	NN
cord-293701-u4ntxo0y	151	15	techniques	technique	NNS
cord-293701-u4ntxo0y	151	16	,	,	,
cord-293701-u4ntxo0y	151	17	including	include	VBG
cord-293701-u4ntxo0y	151	18	subunit	subunit	NN
cord-293701-u4ntxo0y	151	19	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	151	20	,	,	,
cord-293701-u4ntxo0y	151	21	viral	viral	JJ
cord-293701-u4ntxo0y	151	22	vector	vector	NN
cord-293701-u4ntxo0y	151	23	and	and	CC
cord-293701-u4ntxo0y	151	24	DNA	dna	NN
cord-293701-u4ntxo0y	151	25	-	-	HYPH
cord-293701-u4ntxo0y	151	26	based	base	VBN
cord-293701-u4ntxo0y	151	27	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	151	28	,	,	,
cord-293701-u4ntxo0y	151	29	and	and	CC
cord-293701-u4ntxo0y	151	30	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	151	31	and	and	CC
cord-293701-u4ntxo0y	151	32	live	live	JJ
cord-293701-u4ntxo0y	151	33	attenuated	attenuated	JJ
cord-293701-u4ntxo0y	151	34	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	151	35	,	,	,
cord-293701-u4ntxo0y	151	36	have	have	VBP
cord-293701-u4ntxo0y	151	37	been	be	VBN
cord-293701-u4ntxo0y	151	38	applied	apply	VBN
cord-293701-u4ntxo0y	151	39	to	to	TO
cord-293701-u4ntxo0y	151	40	develop	develop	VB
cord-293701-u4ntxo0y	151	41	MERS	MERS	NNP
cord-293701-u4ntxo0y	151	42	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	151	43	85	85	CD
cord-293701-u4ntxo0y	151	44	.	.	.
cord-293701-u4ntxo0y	152	1	Many	many	JJ
cord-293701-u4ntxo0y	152	2	of	of	IN
cord-293701-u4ntxo0y	152	3	them	-PRON-	PRP
cord-293701-u4ntxo0y	152	4	could	could	MD
cord-293701-u4ntxo0y	152	5	induce	induce	VB
cord-293701-u4ntxo0y	152	6	adequate	adequate	JJ
cord-293701-u4ntxo0y	152	7	immune	immune	JJ
cord-293701-u4ntxo0y	152	8	responses	response	NNS
cord-293701-u4ntxo0y	152	9	and	and	CC
cord-293701-u4ntxo0y	152	10	protect	protect	VB
cord-293701-u4ntxo0y	152	11	vaccinated	vaccinated	JJ
cord-293701-u4ntxo0y	152	12	animals	animal	NNS
cord-293701-u4ntxo0y	152	13	from	from	IN
cord-293701-u4ntxo0y	152	14	subsequent	subsequent	JJ
cord-293701-u4ntxo0y	152	15	MERS	MERS	NNP
cord-293701-u4ntxo0y	152	16	-	-	HYPH
cord-293701-u4ntxo0y	152	17	CoV	CoV	NNP
cord-293701-u4ntxo0y	152	18	infection	infection	NN
cord-293701-u4ntxo0y	152	19	86	86	CD
cord-293701-u4ntxo0y	152	20	.	.	.
cord-293701-u4ntxo0y	153	1	However	however	RB
cord-293701-u4ntxo0y	153	2	,	,	,
cord-293701-u4ntxo0y	153	3	two	two	CD
cord-293701-u4ntxo0y	153	4	studies	study	NNS
cord-293701-u4ntxo0y	153	5	independently	independently	RB
cord-293701-u4ntxo0y	153	6	reported	report	VBD
cord-293701-u4ntxo0y	153	7	that	that	IN
cord-293701-u4ntxo0y	153	8	mice	mouse	NNS
cord-293701-u4ntxo0y	153	9	vaccinated	vaccinate	VBN
cord-293701-u4ntxo0y	153	10	with	with	IN
cord-293701-u4ntxo0y	153	11	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	153	12	MERS	MERS	NNP
cord-293701-u4ntxo0y	153	13	-	-	HYPH
cord-293701-u4ntxo0y	153	14	CoV	CoV	NNP
cord-293701-u4ntxo0y	153	15	developed	develop	VBD
cord-293701-u4ntxo0y	153	16	T	T	NNP
cord-293701-u4ntxo0y	153	17	H	H	NNP
cord-293701-u4ntxo0y	153	18	2	2	CD
cord-293701-u4ntxo0y	153	19	cell	cell	NN
cord-293701-u4ntxo0y	153	20	-	-	HYPH
cord-293701-u4ntxo0y	153	21	biased	bias	VBN
cord-293701-u4ntxo0y	153	22	immune	immune	JJ
cord-293701-u4ntxo0y	153	23	responses	response	NNS
cord-293701-u4ntxo0y	153	24	and	and	CC
cord-293701-u4ntxo0y	153	25	increased	increase	VBN
cord-293701-u4ntxo0y	153	26	eosinophil	eosinophil	NN
cord-293701-u4ntxo0y	153	27	infiltrates	infiltrate	VBZ
cord-293701-u4ntxo0y	153	28	after	after	IN
cord-293701-u4ntxo0y	153	29	viral	viral	JJ
cord-293701-u4ntxo0y	153	30	www.nature.com/nrmicro	www.nature.com/nrmicro	NNP
cord-293701-u4ntxo0y	153	31	challenge	challenge	NN
cord-293701-u4ntxo0y	153	32	87	87	CD
cord-293701-u4ntxo0y	153	33	,	,	,
cord-293701-u4ntxo0y	153	34	88	88	CD
cord-293701-u4ntxo0y	153	35	.	.	.
cord-293701-u4ntxo0y	154	1	Several	several	JJ
cord-293701-u4ntxo0y	154	2	lines	line	NNS
cord-293701-u4ntxo0y	154	3	of	of	IN
cord-293701-u4ntxo0y	154	4	evidence	evidence	NN
cord-293701-u4ntxo0y	154	5	have	have	VBP
cord-293701-u4ntxo0y	154	6	demonstrated	demonstrate	VBN
cord-293701-u4ntxo0y	154	7	that	that	IN
cord-293701-u4ntxo0y	154	8	MERS	MERS	NNP
cord-293701-u4ntxo0y	154	9	S	S	NNP
cord-293701-u4ntxo0y	154	10	protein	protein	NN
cord-293701-u4ntxo0y	154	11	-	-	HYPH
cord-293701-u4ntxo0y	154	12	specific	specific	JJ
cord-293701-u4ntxo0y	154	13	antibodies	antibody	NNS
cord-293701-u4ntxo0y	154	14	are	be	VBP
cord-293701-u4ntxo0y	154	15	able	able	JJ
cord-293701-u4ntxo0y	154	16	to	to	TO
cord-293701-u4ntxo0y	154	17	mediate	mediate	VB
cord-293701-u4ntxo0y	154	18	ADE	ADE	NNP
cord-293701-u4ntxo0y	154	19	.	.	.
cord-293701-u4ntxo0y	155	1	A	a	DT
cord-293701-u4ntxo0y	155	2	monoclonal	monoclonal	JJ
cord-293701-u4ntxo0y	155	3	antibody	antibody	NN
cord-293701-u4ntxo0y	155	4	induced	induce	VBN
cord-293701-u4ntxo0y	155	5	by	by	IN
cord-293701-u4ntxo0y	155	6	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	155	7	MERS	MERS	NNP
cord-293701-u4ntxo0y	155	8	-	-	HYPH
cord-293701-u4ntxo0y	155	9	CoV	CoV	NNP
cord-293701-u4ntxo0y	155	10	S1	s1	NN
cord-293701-u4ntxo0y	155	11	bound	bind	VBN
cord-293701-u4ntxo0y	155	12	to	to	IN
cord-293701-u4ntxo0y	155	13	cell	cell	NN
cord-293701-u4ntxo0y	155	14	surface	surface	NN
cord-293701-u4ntxo0y	155	15	IgG	IgG	NNP
cord-293701-u4ntxo0y	155	16	FcR	FcR	NNP
cord-293701-u4ntxo0y	155	17	and	and	CC
cord-293701-u4ntxo0y	155	18	mediated	mediate	VBN
cord-293701-u4ntxo0y	155	19	viral	viral	JJ
cord-293701-u4ntxo0y	155	20	entry	entry	NN
cord-293701-u4ntxo0y	155	21	into	into	IN
cord-293701-u4ntxo0y	155	22	HEK293	HEK293	NNP
cord-293701-u4ntxo0y	155	23	T	T	NNP
cord-293701-u4ntxo0y	155	24	cells	cell	NNS
cord-293701-u4ntxo0y	155	25	exogenously	exogenously	RB
cord-293701-u4ntxo0y	155	26	expressing	express	VBG
cord-293701-u4ntxo0y	155	27	FcRs	FcRs	NNP
cord-293701-u4ntxo0y	155	28	and	and	CC
cord-293701-u4ntxo0y	155	29	macrophages	macrophage	NNS
cord-293701-u4ntxo0y	155	30	(	(	-LRB-
cord-293701-u4ntxo0y	155	31	induced	induce	VBN
cord-293701-u4ntxo0y	155	32	from	from	IN
cord-293701-u4ntxo0y	155	33	THP-1	THP-1	NNP
cord-293701-u4ntxo0y	155	34	monocytes	monocyte	NNS
cord-293701-u4ntxo0y	155	35	)	)	-RRB-
cord-293701-u4ntxo0y	155	36	endogenously	endogenously	RB
cord-293701-u4ntxo0y	155	37	expressing	express	VBG
cord-293701-u4ntxo0y	155	38	FcRs	FcRs	NNP
cord-293701-u4ntxo0y	155	39	through	through	IN
cord-293701-u4ntxo0y	155	40	canonical	canonical	JJ
cord-293701-u4ntxo0y	155	41	viral	viral	JJ
cord-293701-u4ntxo0y	155	42	receptor	receptor	NN
cord-293701-u4ntxo0y	155	43	-	-	HYPH
cord-293701-u4ntxo0y	155	44	dependent	dependent	JJ
cord-293701-u4ntxo0y	155	45	pathways	pathway	NNS
cord-293701-u4ntxo0y	155	46	89	89	CD
cord-293701-u4ntxo0y	155	47	.	.	.
cord-293701-u4ntxo0y	156	1	Rabbits	rabbit	NNS
cord-293701-u4ntxo0y	156	2	infected	infect	VBN
cord-293701-u4ntxo0y	156	3	with	with	IN
cord-293701-u4ntxo0y	156	4	MERS	MERS	NNP
cord-293701-u4ntxo0y	156	5	-	-	HYPH
cord-293701-u4ntxo0y	156	6	CoV	CoV	NNP
cord-293701-u4ntxo0y	156	7	developed	develop	VBD
cord-293701-u4ntxo0y	156	8	MERS	MERS	NNP
cord-293701-u4ntxo0y	156	9	-	-	HYPH
cord-293701-u4ntxo0y	156	10	CoV	CoV	NNP
cord-293701-u4ntxo0y	156	11	S	S	NNP
cord-293701-u4ntxo0y	156	12	protein	protein	NN
cord-293701-u4ntxo0y	156	13	-	-	HYPH
cord-293701-u4ntxo0y	156	14	specific	specific	JJ
cord-293701-u4ntxo0y	156	15	antibodies	antibody	NNS
cord-293701-u4ntxo0y	156	16	without	without	IN
cord-293701-u4ntxo0y	156	17	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	156	18	activity	activity	NN
cord-293701-u4ntxo0y	156	19	and	and	CC
cord-293701-u4ntxo0y	156	20	protection	protection	NN
cord-293701-u4ntxo0y	156	21	of	of	IN
cord-293701-u4ntxo0y	156	22	animals	animal	NNS
cord-293701-u4ntxo0y	156	23	against	against	IN
cord-293701-u4ntxo0y	156	24	reinfection	reinfection	NN
cord-293701-u4ntxo0y	156	25	,	,	,
cord-293701-u4ntxo0y	156	26	and	and	CC
cord-293701-u4ntxo0y	156	27	concerningly	concerningly	NN
cord-293701-u4ntxo0y	156	28	,	,	,
cord-293701-u4ntxo0y	156	29	MERS	MERS	NNP
cord-293701-u4ntxo0y	156	30	-	-	HYPH
cord-293701-u4ntxo0y	156	31	CoV	cov	NN
cord-293701-u4ntxo0y	156	32	-	-	HYPH
cord-293701-u4ntxo0y	156	33	reinfected	reinfecte	VBN
cord-293701-u4ntxo0y	156	34	rabbits	rabbit	NNS
cord-293701-u4ntxo0y	156	35	showed	show	VBD
cord-293701-u4ntxo0y	156	36	enhanced	enhanced	JJ
cord-293701-u4ntxo0y	156	37	pulmonary	pulmonary	JJ
cord-293701-u4ntxo0y	156	38	inflammation	inflammation	NN
cord-293701-u4ntxo0y	156	39	associated	associate	VBN
cord-293701-u4ntxo0y	156	40	with	with	IN
cord-293701-u4ntxo0y	156	41	complement	complement	JJ
cord-293701-u4ntxo0y	156	42	activation	activation	NN
cord-293701-u4ntxo0y	156	43	90	90	CD
cord-293701-u4ntxo0y	156	44	.	.	.
cord-293701-u4ntxo0y	157	1	Overall	overall	RB
cord-293701-u4ntxo0y	157	2	,	,	,
cord-293701-u4ntxo0y	157	3	signs	sign	NNS
cord-293701-u4ntxo0y	157	4	of	of	IN
cord-293701-u4ntxo0y	157	5	VADE	VADE	NNP
cord-293701-u4ntxo0y	157	6	are	be	VBP
cord-293701-u4ntxo0y	157	7	less	less	RBR
cord-293701-u4ntxo0y	157	8	prominent	prominent	JJ
cord-293701-u4ntxo0y	157	9	for	for	IN
cord-293701-u4ntxo0y	157	10	MERS	MERS	NNP
cord-293701-u4ntxo0y	157	11	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	157	12	than	than	IN
cord-293701-u4ntxo0y	157	13	for	for	IN
cord-293701-u4ntxo0y	157	14	SARS	SARS	NNP
cord-293701-u4ntxo0y	157	15	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	157	16	.	.	.
cord-293701-u4ntxo0y	158	1	Currently	currently	RB
cord-293701-u4ntxo0y	158	2	,	,	,
cord-293701-u4ntxo0y	158	3	one	one	CD
cord-293701-u4ntxo0y	158	4	DNA	dna	NN
cord-293701-u4ntxo0y	158	5	MERS	MERS	NNP
cord-293701-u4ntxo0y	158	6	vaccine	vaccine	NN
cord-293701-u4ntxo0y	158	7	(	(	-LRB-
cord-293701-u4ntxo0y	158	8	INO-4700	INO-4700	NNP
cord-293701-u4ntxo0y	158	9	)	)	-RRB-
cord-293701-u4ntxo0y	158	10	and	and	CC
cord-293701-u4ntxo0y	158	11	two	two	CD
cord-293701-u4ntxo0y	158	12	viral	viral	JJ
cord-293701-u4ntxo0y	158	13	-	-	HYPH
cord-293701-u4ntxo0y	158	14	vectored	vectored	JJ
cord-293701-u4ntxo0y	158	15	MERS	MERS	NNP
cord-293701-u4ntxo0y	158	16	S	S	NNP
cord-293701-u4ntxo0y	158	17	protein	protein	NN
cord-293701-u4ntxo0y	158	18	-	-	HYPH
cord-293701-u4ntxo0y	158	19	based	base	VBN
cord-293701-u4ntxo0y	158	20	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	158	21	have	have	VBP
cord-293701-u4ntxo0y	158	22	shown	show	VBN
cord-293701-u4ntxo0y	158	23	a	a	DT
cord-293701-u4ntxo0y	158	24	favourable	favourable	JJ
cord-293701-u4ntxo0y	158	25	safety	safety	NN
cord-293701-u4ntxo0y	158	26	profile	profile	NN
cord-293701-u4ntxo0y	158	27	and	and	CC
cord-293701-u4ntxo0y	158	28	induced	induce	VBN
cord-293701-u4ntxo0y	158	29	humoral	humoral	JJ
cord-293701-u4ntxo0y	158	30	and	and	CC
cord-293701-u4ntxo0y	158	31	cellular	cellular	JJ
cord-293701-u4ntxo0y	158	32	immune	immune	JJ
cord-293701-u4ntxo0y	158	33	responses	response	NNS
cord-293701-u4ntxo0y	158	34	against	against	IN
cord-293701-u4ntxo0y	158	35	MERS	MERS	NNP
cord-293701-u4ntxo0y	158	36	-	-	HYPH
cord-293701-u4ntxo0y	158	37	CoV	CoV	NNP
cord-293701-u4ntxo0y	158	38	in	in	IN
cord-293701-u4ntxo0y	158	39	phase	phase	NN
cord-293701-u4ntxo0y	159	1	I	-PRON-	PRP
cord-293701-u4ntxo0y	159	2	clinical	clinical	JJ
cord-293701-u4ntxo0y	159	3	trials	trial	NNS
cord-293701-u4ntxo0y	159	4	[	[	-LRB-
cord-293701-u4ntxo0y	159	5	91	91	CD
cord-293701-u4ntxo0y	159	6	]	]	-RRB-
cord-293701-u4ntxo0y	160	1	[	[	-LRB-
cord-293701-u4ntxo0y	160	2	92	92	CD
cord-293701-u4ntxo0y	160	3	]	]	-RRB-
cord-293701-u4ntxo0y	160	4	[	[	-LRB-
cord-293701-u4ntxo0y	160	5	93	93	CD
cord-293701-u4ntxo0y	160	6	]	]	-RRB-
cord-293701-u4ntxo0y	160	7	.	.	.
cord-293701-u4ntxo0y	161	1	The	the	DT
cord-293701-u4ntxo0y	161	2	VADE	VADE	NNP
cord-293701-u4ntxo0y	161	3	phenomena	phenomena	JJ
cord-293701-u4ntxo0y	161	4	in	in	IN
cord-293701-u4ntxo0y	161	5	SARS	SARS	NNP
cord-293701-u4ntxo0y	161	6	and	and	CC
cord-293701-u4ntxo0y	161	7	MERS	MERS	NNP
cord-293701-u4ntxo0y	161	8	vaccine	vaccine	NN
cord-293701-u4ntxo0y	161	9	development	development	NN
cord-293701-u4ntxo0y	161	10	described	describe	VBN
cord-293701-u4ntxo0y	161	11	above	above	IN
cord-293701-u4ntxo0y	161	12	further	further	RB
cord-293701-u4ntxo0y	161	13	highlight	highlight	VB
cord-293701-u4ntxo0y	161	14	the	the	DT
cord-293701-u4ntxo0y	161	15	lessons	lesson	NNS
cord-293701-u4ntxo0y	161	16	we	-PRON-	PRP
cord-293701-u4ntxo0y	161	17	have	have	VBP
cord-293701-u4ntxo0y	161	18	learnt	learn	VBN
cord-293701-u4ntxo0y	161	19	from	from	IN
cord-293701-u4ntxo0y	161	20	RSV	RSV	NNP
cord-293701-u4ntxo0y	161	21	and	and	CC
cord-293701-u4ntxo0y	161	22	DENV	DENV	NNP
cord-293701-u4ntxo0y	161	23	.	.	.
cord-293701-u4ntxo0y	162	1	First	first	RB
cord-293701-u4ntxo0y	162	2	,	,	,
cord-293701-u4ntxo0y	162	3	the	the	DT
cord-293701-u4ntxo0y	162	4	vaccine	vaccine	NN
cord-293701-u4ntxo0y	162	5	candidate	candidate	NN
cord-293701-u4ntxo0y	162	6	for	for	IN
cord-293701-u4ntxo0y	162	7	SARS	SARS	NNP
cord-293701-u4ntxo0y	162	8	-	-	HYPH
cord-293701-u4ntxo0y	162	9	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	162	10	should	should	MD
cord-293701-u4ntxo0y	162	11	induce	induce	VB
cord-293701-u4ntxo0y	162	12	a	a	DT
cord-293701-u4ntxo0y	162	13	balanced	balanced	JJ
cord-293701-u4ntxo0y	162	14	T	T	NNP
cord-293701-u4ntxo0y	162	15	cell	cell	NN
cord-293701-u4ntxo0y	162	16	response	response	NN
cord-293701-u4ntxo0y	162	17	.	.	.
cord-293701-u4ntxo0y	163	1	Particularly	particularly	RB
cord-293701-u4ntxo0y	163	2	,	,	,
cord-293701-u4ntxo0y	163	3	the	the	DT
cord-293701-u4ntxo0y	163	4	T	T	NNP
cord-293701-u4ntxo0y	163	5	H	h	NN
cord-293701-u4ntxo0y	163	6	1	1	CD
cord-293701-u4ntxo0y	163	7	cell	cell	NN
cord-293701-u4ntxo0y	163	8	and	and	CC
cord-293701-u4ntxo0y	163	9	T	t	NN
cord-293701-u4ntxo0y	163	10	H	h	NN
cord-293701-u4ntxo0y	163	11	2	2	CD
cord-293701-u4ntxo0y	163	12	cell	cell	NN
cord-293701-u4ntxo0y	163	13	immune	immune	JJ
cord-293701-u4ntxo0y	163	14	response	response	NN
cord-293701-u4ntxo0y	163	15	should	should	MD
cord-293701-u4ntxo0y	163	16	be	be	VB
cord-293701-u4ntxo0y	163	17	evaluated	evaluate	VBN
cord-293701-u4ntxo0y	163	18	in	in	IN
cord-293701-u4ntxo0y	163	19	animals	animal	NNS
cord-293701-u4ntxo0y	163	20	and	and	CC
cord-293701-u4ntxo0y	163	21	humans	human	NNS
cord-293701-u4ntxo0y	163	22	after	after	IN
cord-293701-u4ntxo0y	163	23	vaccination	vaccination	NN
cord-293701-u4ntxo0y	163	24	.	.	.
cord-293701-u4ntxo0y	164	1	Second	second	RB
cord-293701-u4ntxo0y	164	2	,	,	,
cord-293701-u4ntxo0y	164	3	the	the	DT
cord-293701-u4ntxo0y	164	4	phenomenon	phenomenon	NN
cord-293701-u4ntxo0y	164	5	that	that	IN
cord-293701-u4ntxo0y	164	6	only	only	RB
cord-293701-u4ntxo0y	164	7	diluted	dilute	VBN
cord-293701-u4ntxo0y	164	8	SARS	SARS	NNP
cord-293701-u4ntxo0y	164	9	-	-	HYPH
cord-293701-u4ntxo0y	164	10	CoV	CoV	NNP
cord-293701-u4ntxo0y	164	11	S	S	NNP
cord-293701-u4ntxo0y	164	12	protein	protein	NN
cord-293701-u4ntxo0y	164	13	-	-	HYPH
cord-293701-u4ntxo0y	164	14	specific	specific	JJ
cord-293701-u4ntxo0y	164	15	antibodies	antibody	NNS
cord-293701-u4ntxo0y	164	16	resulted	result	VBD
cord-293701-u4ntxo0y	164	17	in	in	IN
cord-293701-u4ntxo0y	164	18	increased	increase	VBN
cord-293701-u4ntxo0y	164	19	viral	viral	JJ
cord-293701-u4ntxo0y	164	20	infectivity	infectivity	NN
cord-293701-u4ntxo0y	164	21	84	84	CD
cord-293701-u4ntxo0y	164	22	indicates	indicate	VBZ
cord-293701-u4ntxo0y	164	23	that	that	IN
cord-293701-u4ntxo0y	164	24	VADE	VADE	NNP
cord-293701-u4ntxo0y	164	25	is	be	VBZ
cord-293701-u4ntxo0y	164	26	related	relate	VBN
cord-293701-u4ntxo0y	164	27	to	to	IN
cord-293701-u4ntxo0y	164	28	the	the	DT
cord-293701-u4ntxo0y	164	29	antibody	antibody	NN
cord-293701-u4ntxo0y	164	30	titre	titre	NN
cord-293701-u4ntxo0y	164	31	in	in	IN
cord-293701-u4ntxo0y	164	32	immunized	immunize	VBN
cord-293701-u4ntxo0y	164	33	subjects	subject	NNS
cord-293701-u4ntxo0y	164	34	.	.	.
cord-293701-u4ntxo0y	165	1	The	the	DT
cord-293701-u4ntxo0y	165	2	putative	putative	JJ
cord-293701-u4ntxo0y	165	3	mechanisms	mechanism	NNS
cord-293701-u4ntxo0y	165	4	of	of	IN
cord-293701-u4ntxo0y	165	5	VADE	VADE	NNP
cord-293701-u4ntxo0y	166	1	Currently	currently	RB
cord-293701-u4ntxo0y	166	2	,	,	,
cord-293701-u4ntxo0y	166	3	the	the	DT
cord-293701-u4ntxo0y	166	4	mechanisms	mechanism	NNS
cord-293701-u4ntxo0y	166	5	that	that	WDT
cord-293701-u4ntxo0y	166	6	underlie	underlie	VBP
cord-293701-u4ntxo0y	166	7	VADE	VADE	NNP
cord-293701-u4ntxo0y	166	8	have	have	VBP
cord-293701-u4ntxo0y	166	9	not	not	RB
cord-293701-u4ntxo0y	166	10	been	be	VBN
cord-293701-u4ntxo0y	166	11	clearly	clearly	RB
cord-293701-u4ntxo0y	166	12	defined	define	VBN
cord-293701-u4ntxo0y	166	13	because	because	IN
cord-293701-u4ntxo0y	166	14	its	-PRON-	PRP$
cord-293701-u4ntxo0y	166	15	emergence	emergence	NN
cord-293701-u4ntxo0y	166	16	is	be	VBZ
cord-293701-u4ntxo0y	166	17	highly	highly	RB
cord-293701-u4ntxo0y	166	18	virus	virus	NN
cord-293701-u4ntxo0y	166	19	,	,	,
cord-293701-u4ntxo0y	166	20	host	host	NN
cord-293701-u4ntxo0y	166	21	and	and	CC
cord-293701-u4ntxo0y	166	22	antigen	antigen	NN
cord-293701-u4ntxo0y	166	23	specific	specific	JJ
cord-293701-u4ntxo0y	166	24	.	.	.
cord-293701-u4ntxo0y	167	1	However	however	RB
cord-293701-u4ntxo0y	167	2	,	,	,
cord-293701-u4ntxo0y	167	3	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	167	4	have	have	VBP
cord-293701-u4ntxo0y	167	5	several	several	JJ
cord-293701-u4ntxo0y	167	6	features	feature	NNS
cord-293701-u4ntxo0y	167	7	in	in	IN
cord-293701-u4ntxo0y	167	8	common	common	JJ
cord-293701-u4ntxo0y	167	9	that	that	WDT
cord-293701-u4ntxo0y	167	10	can	can	MD
cord-293701-u4ntxo0y	167	11	induce	induce	VB
cord-293701-u4ntxo0y	167	12	VADE	VADE	NNP
cord-293701-u4ntxo0y	167	13	in	in	IN
cord-293701-u4ntxo0y	167	14	vivo	vivo	NN
cord-293701-u4ntxo0y	167	15	.	.	.
cord-293701-u4ntxo0y	168	1	First	first	RB
cord-293701-u4ntxo0y	168	2	,	,	,
cord-293701-u4ntxo0y	168	3	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	168	4	for	for	IN
cord-293701-u4ntxo0y	168	5	infection	infection	NN
cord-293701-u4ntxo0y	168	6	by	by	IN
cord-293701-u4ntxo0y	168	7	viruses	virus	NNS
cord-293701-u4ntxo0y	168	8	that	that	WDT
cord-293701-u4ntxo0y	168	9	target	target	VBP
cord-293701-u4ntxo0y	168	10	and	and	CC
cord-293701-u4ntxo0y	168	11	replicate	replicate	VBP
cord-293701-u4ntxo0y	168	12	in	in	IN
cord-293701-u4ntxo0y	168	13	cells	cell	NNS
cord-293701-u4ntxo0y	168	14	with	with	IN
cord-293701-u4ntxo0y	168	15	FcRs	FcRs	NNP
cord-293701-u4ntxo0y	168	16	,	,	,
cord-293701-u4ntxo0y	168	17	including	include	VBG
cord-293701-u4ntxo0y	168	18	DENV	DENV	NNP
cord-293701-u4ntxo0y	168	19	and	and	CC
cord-293701-u4ntxo0y	168	20	Ebola	Ebola	NNP
cord-293701-u4ntxo0y	168	21	virus	virus	NN
cord-293701-u4ntxo0y	168	22	,	,	,
cord-293701-u4ntxo0y	168	23	are	be	VBP
cord-293701-u4ntxo0y	168	24	likely	likely	JJ
cord-293701-u4ntxo0y	168	25	to	to	TO
cord-293701-u4ntxo0y	168	26	induce	induce	VB
cord-293701-u4ntxo0y	168	27	VADE	VADE	NNP
cord-293701-u4ntxo0y	168	28	94	94	CD
cord-293701-u4ntxo0y	168	29	,	,	,
cord-293701-u4ntxo0y	168	30	especially	especially	RB
cord-293701-u4ntxo0y	168	31	ADE	ADE	NNP
cord-293701-u4ntxo0y	168	32	.	.	.
cord-293701-u4ntxo0y	169	1	Up	up	IN
cord-293701-u4ntxo0y	169	2	to	to	IN
cord-293701-u4ntxo0y	169	3	now	now	RB
cord-293701-u4ntxo0y	169	4	,	,	,
cord-293701-u4ntxo0y	169	5	only	only	RB
cord-293701-u4ntxo0y	169	6	one	one	CD
cord-293701-u4ntxo0y	169	7	study	study	NN
cord-293701-u4ntxo0y	169	8	has	have	VBZ
cord-293701-u4ntxo0y	169	9	reported	report	VBN
cord-293701-u4ntxo0y	169	10	that	that	IN
cord-293701-u4ntxo0y	169	11	monocytes	monocyte	NNS
cord-293701-u4ntxo0y	169	12	,	,	,
cord-293701-u4ntxo0y	169	13	as	as	RB
cord-293701-u4ntxo0y	169	14	well	well	RB
cord-293701-u4ntxo0y	169	15	as	as	IN
cord-293701-u4ntxo0y	169	16	B	b	NN
cord-293701-u4ntxo0y	169	17	and	and	CC
cord-293701-u4ntxo0y	169	18	T	t	NN
cord-293701-u4ntxo0y	169	19	lymphocytes	lymphocyte	NNS
cord-293701-u4ntxo0y	169	20	,	,	,
cord-293701-u4ntxo0y	169	21	are	be	VBP
cord-293701-u4ntxo0y	169	22	susceptible	susceptible	JJ
cord-293701-u4ntxo0y	169	23	to	to	IN
cord-293701-u4ntxo0y	169	24	SARS	SARS	NNP
cord-293701-u4ntxo0y	169	25	-	-	HYPH
cord-293701-u4ntxo0y	169	26	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	169	27	active	active	JJ
cord-293701-u4ntxo0y	169	28	infection	infection	NN
cord-293701-u4ntxo0y	169	29	,	,	,
cord-293701-u4ntxo0y	169	30	and	and	CC
cord-293701-u4ntxo0y	169	31	this	this	DT
cord-293701-u4ntxo0y	169	32	report	report	NN
cord-293701-u4ntxo0y	169	33	has	have	VBZ
cord-293701-u4ntxo0y	169	34	not	not	RB
cord-293701-u4ntxo0y	169	35	been	be	VBN
cord-293701-u4ntxo0y	169	36	peer	peer	NN
cord-293701-u4ntxo0y	169	37	-	-	HYPH
cord-293701-u4ntxo0y	169	38	reviewed	review	VBN
cord-293701-u4ntxo0y	169	39	95	95	CD
cord-293701-u4ntxo0y	169	40	.	.	.
cord-293701-u4ntxo0y	170	1	Therefore	therefore	RB
cord-293701-u4ntxo0y	170	2	,	,	,
cord-293701-u4ntxo0y	170	3	more	more	JJR
cord-293701-u4ntxo0y	170	4	effort	effort	NN
cord-293701-u4ntxo0y	170	5	is	be	VBZ
cord-293701-u4ntxo0y	170	6	needed	need	VBN
cord-293701-u4ntxo0y	170	7	to	to	TO
cord-293701-u4ntxo0y	170	8	relieve	relieve	VB
cord-293701-u4ntxo0y	170	9	this	this	DT
cord-293701-u4ntxo0y	170	10	concern	concern	NN
cord-293701-u4ntxo0y	170	11	.	.	.
cord-293701-u4ntxo0y	171	1	Second	second	RB
cord-293701-u4ntxo0y	171	2	,	,	,
cord-293701-u4ntxo0y	171	3	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	171	4	for	for	IN
cord-293701-u4ntxo0y	171	5	infection	infection	NN
cord-293701-u4ntxo0y	171	6	by	by	IN
cord-293701-u4ntxo0y	171	7	viruses	virus	NNS
cord-293701-u4ntxo0y	171	8	that	that	WDT
cord-293701-u4ntxo0y	171	9	will	will	MD
cord-293701-u4ntxo0y	171	10	cause	cause	VB
cord-293701-u4ntxo0y	171	11	inflammatory	inflammatory	JJ
cord-293701-u4ntxo0y	171	12	damage	damage	NN
cord-293701-u4ntxo0y	171	13	are	be	VBP
cord-293701-u4ntxo0y	171	14	likely	likely	JJ
cord-293701-u4ntxo0y	171	15	to	to	TO
cord-293701-u4ntxo0y	171	16	result	result	VB
cord-293701-u4ntxo0y	171	17	in	in	IN
cord-293701-u4ntxo0y	171	18	VADE	VADE	NNP
cord-293701-u4ntxo0y	171	19	;	;	:
cord-293701-u4ntxo0y	171	20	for	for	IN
cord-293701-u4ntxo0y	171	21	example	example	NN
cord-293701-u4ntxo0y	171	22	,	,	,
cord-293701-u4ntxo0y	171	23	SARS	SARS	NNP
cord-293701-u4ntxo0y	171	24	-	-	HYPH
cord-293701-u4ntxo0y	171	25	CoV	CoV	NNP
cord-293701-u4ntxo0y	171	26	and	and	CC
cord-293701-u4ntxo0y	171	27	RSV	RSV	NNP
cord-293701-u4ntxo0y	171	28	96	96	CD
cord-293701-u4ntxo0y	171	29	.	.	.
cord-293701-u4ntxo0y	172	1	About	about	RB
cord-293701-u4ntxo0y	172	2	13.9	13.9	CD
cord-293701-u4ntxo0y	172	3	%	%	NN
cord-293701-u4ntxo0y	172	4	of	of	IN
cord-293701-u4ntxo0y	172	5	patients	patient	NNS
cord-293701-u4ntxo0y	172	6	with	with	IN
cord-293701-u4ntxo0y	172	7	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	172	8	advanced	advanced	JJ
cord-293701-u4ntxo0y	172	9	to	to	IN
cord-293701-u4ntxo0y	172	10	severe	severe	JJ
cord-293701-u4ntxo0y	172	11	pneumonia	pneumonia	NN
cord-293701-u4ntxo0y	172	12	97	97	CD
cord-293701-u4ntxo0y	172	13	,	,	,
cord-293701-u4ntxo0y	172	14	in	in	IN
cord-293701-u4ntxo0y	172	15	which	which	WDT
cord-293701-u4ntxo0y	172	16	inflammatory	inflammatory	JJ
cord-293701-u4ntxo0y	172	17	responses	response	NNS
cord-293701-u4ntxo0y	172	18	contributed	contribute	VBD
cord-293701-u4ntxo0y	172	19	to	to	IN
cord-293701-u4ntxo0y	172	20	pathology	pathology	NN
cord-293701-u4ntxo0y	172	21	.	.	.
cord-293701-u4ntxo0y	173	1	A	a	DT
cord-293701-u4ntxo0y	173	2	preliminary	preliminary	JJ
cord-293701-u4ntxo0y	173	3	report	report	NN
cord-293701-u4ntxo0y	173	4	showed	show	VBD
cord-293701-u4ntxo0y	173	5	that	that	IN
cord-293701-u4ntxo0y	173	6	the	the	DT
cord-293701-u4ntxo0y	173	7	28-day	28-day	CD
cord-293701-u4ntxo0y	173	8	mortality	mortality	NN
cord-293701-u4ntxo0y	173	9	was	be	VBD
cord-293701-u4ntxo0y	173	10	lower	low	JJR
cord-293701-u4ntxo0y	173	11	in	in	IN
cord-293701-u4ntxo0y	173	12	the	the	DT
cord-293701-u4ntxo0y	173	13	group	group	NN
cord-293701-u4ntxo0y	173	14	of	of	IN
cord-293701-u4ntxo0y	173	15	patients	patient	NNS
cord-293701-u4ntxo0y	173	16	with	with	IN
cord-293701-u4ntxo0y	173	17	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	173	18	receiving	receive	VBG
cord-293701-u4ntxo0y	173	19	dexamethasone	dexamethasone	NN
cord-293701-u4ntxo0y	173	20	,	,	,
cord-293701-u4ntxo0y	173	21	which	which	WDT
cord-293701-u4ntxo0y	173	22	has	have	VBZ
cord-293701-u4ntxo0y	173	23	anti	anti	JJ
cord-293701-u4ntxo0y	173	24	-	-	JJ
cord-293701-u4ntxo0y	173	25	inflammatory	inflammatory	JJ
cord-293701-u4ntxo0y	173	26	effects	effect	NNS
cord-293701-u4ntxo0y	173	27	,	,	,
cord-293701-u4ntxo0y	173	28	plus	plus	CC
cord-293701-u4ntxo0y	173	29	usual	usual	JJ
cord-293701-u4ntxo0y	173	30	care	care	NN
cord-293701-u4ntxo0y	173	31	compared	compare	VBN
cord-293701-u4ntxo0y	173	32	with	with	IN
cord-293701-u4ntxo0y	173	33	the	the	DT
cord-293701-u4ntxo0y	173	34	patients	patient	NNS
cord-293701-u4ntxo0y	173	35	who	who	WP
cord-293701-u4ntxo0y	173	36	received	receive	VBD
cord-293701-u4ntxo0y	173	37	usual	usual	JJ
cord-293701-u4ntxo0y	173	38	care	care	NN
cord-293701-u4ntxo0y	173	39	alone	alone	RB
cord-293701-u4ntxo0y	173	40	in	in	IN
cord-293701-u4ntxo0y	173	41	a	a	DT
cord-293701-u4ntxo0y	173	42	randomized	randomized	JJ
cord-293701-u4ntxo0y	173	43	trial	trial	NN
cord-293701-u4ntxo0y	173	44	98	98	CD
cord-293701-u4ntxo0y	173	45	.	.	.
cord-293701-u4ntxo0y	174	1	However	however	RB
cord-293701-u4ntxo0y	174	2	,	,	,
cord-293701-u4ntxo0y	174	3	pathology	pathology	NN
cord-293701-u4ntxo0y	174	4	seems	seem	VBZ
cord-293701-u4ntxo0y	174	5	highly	highly	RB
cord-293701-u4ntxo0y	174	6	host	host	NN
cord-293701-u4ntxo0y	174	7	specific	specific	JJ
cord-293701-u4ntxo0y	174	8	;	;	:
cord-293701-u4ntxo0y	174	9	thus	thus	RB
cord-293701-u4ntxo0y	174	10	,	,	,
cord-293701-u4ntxo0y	174	11	no	no	DT
cord-293701-u4ntxo0y	174	12	confirmed	confirm	VBN
cord-293701-u4ntxo0y	174	13	marker	marker	NN
cord-293701-u4ntxo0y	174	14	has	have	VBZ
cord-293701-u4ntxo0y	174	15	been	be	VBN
cord-293701-u4ntxo0y	174	16	identified	identify	VBN
cord-293701-u4ntxo0y	174	17	with	with	IN
cord-293701-u4ntxo0y	174	18	the	the	DT
cord-293701-u4ntxo0y	174	19	ability	ability	NN
cord-293701-u4ntxo0y	174	20	to	to	TO
cord-293701-u4ntxo0y	174	21	predict	predict	VB
cord-293701-u4ntxo0y	174	22	which	which	WDT
cord-293701-u4ntxo0y	174	23	patient	patient	NN
cord-293701-u4ntxo0y	174	24	will	will	MD
cord-293701-u4ntxo0y	174	25	progress	progress	VB
cord-293701-u4ntxo0y	174	26	to	to	IN
cord-293701-u4ntxo0y	174	27	acute	acute	JJ
cord-293701-u4ntxo0y	174	28	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	174	29	distress	distress	NN
cord-293701-u4ntxo0y	174	30	syndrome	syndrome	NN
cord-293701-u4ntxo0y	174	31	.	.	.
cord-293701-u4ntxo0y	175	1	Similarly	similarly	RB
cord-293701-u4ntxo0y	175	2	,	,	,
cord-293701-u4ntxo0y	175	3	it	-PRON-	PRP
cord-293701-u4ntxo0y	175	4	remains	remain	VBZ
cord-293701-u4ntxo0y	175	5	hard	hard	JJ
cord-293701-u4ntxo0y	175	6	to	to	TO
cord-293701-u4ntxo0y	175	7	predict	predict	VB
cord-293701-u4ntxo0y	175	8	which	which	WDT
cord-293701-u4ntxo0y	175	9	antigen	antigen	NN
cord-293701-u4ntxo0y	175	10	will	will	MD
cord-293701-u4ntxo0y	175	11	cause	cause	VB
cord-293701-u4ntxo0y	175	12	VADE	VADE	NNP
cord-293701-u4ntxo0y	175	13	.	.	.
cord-293701-u4ntxo0y	176	1	Third	third	RB
cord-293701-u4ntxo0y	176	2	,	,	,
cord-293701-u4ntxo0y	176	3	antigens	antigen	NNS
cord-293701-u4ntxo0y	176	4	that	that	WDT
cord-293701-u4ntxo0y	176	5	elicit	elicit	VBP
cord-293701-u4ntxo0y	176	6	non	non	JJ
cord-293701-u4ntxo0y	176	7	-	-	JJ
cord-293701-u4ntxo0y	176	8	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	176	9	antibodies	antibody	NNS
cord-293701-u4ntxo0y	176	10	,	,	,
cord-293701-u4ntxo0y	176	11	or	or	CC
cord-293701-u4ntxo0y	176	12	insufficient	insufficient	JJ
cord-293701-u4ntxo0y	176	13	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	176	14	,	,	,
cord-293701-u4ntxo0y	176	15	are	be	VBP
cord-293701-u4ntxo0y	176	16	likely	likely	JJ
cord-293701-u4ntxo0y	176	17	to	to	TO
cord-293701-u4ntxo0y	176	18	cause	cause	VB
cord-293701-u4ntxo0y	176	19	VADE	VADE	NNP
cord-293701-u4ntxo0y	176	20	.	.	.
cord-293701-u4ntxo0y	177	1	Several	several	JJ
cord-293701-u4ntxo0y	177	2	lines	line	NNS
cord-293701-u4ntxo0y	177	3	of	of	IN
cord-293701-u4ntxo0y	177	4	evidence	evidence	NN
cord-293701-u4ntxo0y	177	5	have	have	VBP
cord-293701-u4ntxo0y	177	6	shown	show	VBN
cord-293701-u4ntxo0y	177	7	that	that	IN
cord-293701-u4ntxo0y	177	8	both	both	DT
cord-293701-u4ntxo0y	177	9	RBD	RBD	NNP
cord-293701-u4ntxo0y	177	10	-	-	HYPH
cord-293701-u4ntxo0y	177	11	specific	specific	JJ
cord-293701-u4ntxo0y	177	12	IgG	igg	NN
cord-293701-u4ntxo0y	177	13	and	and	CC
cord-293701-u4ntxo0y	177	14	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	177	15	are	be	VBP
cord-293701-u4ntxo0y	177	16	detectable	detectable	JJ
cord-293701-u4ntxo0y	177	17	in	in	IN
cord-293701-u4ntxo0y	177	18	patients	patient	NNS
cord-293701-u4ntxo0y	177	19	recovering	recover	VBG
cord-293701-u4ntxo0y	177	20	from	from	IN
cord-293701-u4ntxo0y	177	21	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	177	22	(	(	-LRB-
cord-293701-u4ntxo0y	177	23	refs	ref	NNS
cord-293701-u4ntxo0y	177	24	99,100	99,100	CD
cord-293701-u4ntxo0y	177	25	)	)	-RRB-
cord-293701-u4ntxo0y	177	26	.	.	.
cord-293701-u4ntxo0y	178	1	However	however	RB
cord-293701-u4ntxo0y	178	2	,	,	,
cord-293701-u4ntxo0y	178	3	both	both	CC
cord-293701-u4ntxo0y	178	4	the	the	DT
cord-293701-u4ntxo0y	178	5	duration	duration	NN
cord-293701-u4ntxo0y	178	6	of	of	IN
cord-293701-u4ntxo0y	178	7	antibody	antibody	NN
cord-293701-u4ntxo0y	178	8	responses	response	NNS
cord-293701-u4ntxo0y	178	9	and	and	CC
cord-293701-u4ntxo0y	178	10	the	the	DT
cord-293701-u4ntxo0y	178	11	potential	potential	NN
cord-293701-u4ntxo0y	178	12	for	for	IN
cord-293701-u4ntxo0y	178	13	long	long	JJ
cord-293701-u4ntxo0y	178	14	-	-	HYPH
cord-293701-u4ntxo0y	178	15	term	term	NN
cord-293701-u4ntxo0y	178	16	protection	protection	NN
cord-293701-u4ntxo0y	178	17	against	against	IN
cord-293701-u4ntxo0y	178	18	subsequent	subsequent	JJ
cord-293701-u4ntxo0y	178	19	natural	natural	JJ
cord-293701-u4ntxo0y	178	20	infection	infection	NN
cord-293701-u4ntxo0y	178	21	are	be	VBP
cord-293701-u4ntxo0y	178	22	unknown	unknown	JJ
cord-293701-u4ntxo0y	178	23	.	.	.
cord-293701-u4ntxo0y	179	1	There	there	EX
cord-293701-u4ntxo0y	179	2	are	be	VBP
cord-293701-u4ntxo0y	179	3	disparities	disparity	NNS
cord-293701-u4ntxo0y	179	4	in	in	IN
cord-293701-u4ntxo0y	179	5	the	the	DT
cord-293701-u4ntxo0y	179	6	reported	report	VBN
cord-293701-u4ntxo0y	179	7	kinetics	kinetics	NN
cord-293701-u4ntxo0y	179	8	of	of	IN
cord-293701-u4ntxo0y	179	9	antibody	antibody	NN
cord-293701-u4ntxo0y	179	10	responses	response	NNS
cord-293701-u4ntxo0y	179	11	to	to	IN
cord-293701-u4ntxo0y	179	12	SARS	SARS	NNP
cord-293701-u4ntxo0y	179	13	-	-	HYPH
cord-293701-u4ntxo0y	179	14	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	179	15	infection	infection	NN
cord-293701-u4ntxo0y	179	16	.	.	.
cord-293701-u4ntxo0y	180	1	For	for	IN
cord-293701-u4ntxo0y	180	2	example	example	NN
cord-293701-u4ntxo0y	180	3	,	,	,
cord-293701-u4ntxo0y	180	4	one	one	CD
cord-293701-u4ntxo0y	180	5	study	study	NN
cord-293701-u4ntxo0y	180	6	reported	report	VBD
cord-293701-u4ntxo0y	180	7	that	that	IN
cord-293701-u4ntxo0y	180	8	"	"	``
cord-293701-u4ntxo0y	180	9	severe	severe	JJ
cord-293701-u4ntxo0y	180	10	infections	infection	NNS
cord-293701-u4ntxo0y	180	11	were	be	VBD
cord-293701-u4ntxo0y	180	12	associated	associate	VBN
cord-293701-u4ntxo0y	180	13	with	with	IN
cord-293701-u4ntxo0y	180	14	earlier	early	JJR
cord-293701-u4ntxo0y	180	15	seroconversion	seroconversion	NN
cord-293701-u4ntxo0y	180	16	"	"	''
cord-293701-u4ntxo0y	180	17	101	101	CD
cord-293701-u4ntxo0y	180	18	,	,	,
cord-293701-u4ntxo0y	180	19	whereas	whereas	IN
cord-293701-u4ntxo0y	180	20	another	another	DT
cord-293701-u4ntxo0y	180	21	reported	report	VBD
cord-293701-u4ntxo0y	180	22	that	that	IN
cord-293701-u4ntxo0y	180	23	"	"	``
cord-293701-u4ntxo0y	180	24	delayed	delay	VBN
cord-293701-u4ntxo0y	180	25	,	,	,
cord-293701-u4ntxo0y	180	26	but	but	CC
cord-293701-u4ntxo0y	180	27	stronger	strong	JJR
cord-293701-u4ntxo0y	180	28	antibody	antibody	NN
cord-293701-u4ntxo0y	180	29	responses	response	NNS
cord-293701-u4ntxo0y	180	30	were	be	VBD
cord-293701-u4ntxo0y	180	31	observed	observe	VBN
cord-293701-u4ntxo0y	180	32	in	in	IN
cord-293701-u4ntxo0y	180	33	critical	critical	JJ
cord-293701-u4ntxo0y	180	34	patients	patient	NNS
cord-293701-u4ntxo0y	180	35	"	"	''
cord-293701-u4ntxo0y	180	36	102	102	CD
cord-293701-u4ntxo0y	180	37	.	.	.
cord-293701-u4ntxo0y	181	1	Besides	besides	RB
cord-293701-u4ntxo0y	181	2	,	,	,
cord-293701-u4ntxo0y	181	3	two	two	CD
cord-293701-u4ntxo0y	181	4	recent	recent	JJ
cord-293701-u4ntxo0y	181	5	cases	case	NNS
cord-293701-u4ntxo0y	181	6	of	of	IN
cord-293701-u4ntxo0y	181	7	reinfection	reinfection	NN
cord-293701-u4ntxo0y	181	8	with	with	IN
cord-293701-u4ntxo0y	181	9	SARS	SARS	NNP
cord-293701-u4ntxo0y	181	10	-	-	HYPH
cord-293701-u4ntxo0y	181	11	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	181	12	,	,	,
cord-293701-u4ntxo0y	181	13	in	in	IN
cord-293701-u4ntxo0y	181	14	the	the	DT
cord-293701-u4ntxo0y	181	15	United	United	NNP
cord-293701-u4ntxo0y	181	16	States	States	NNP
cord-293701-u4ntxo0y	181	17	and	and	CC
cord-293701-u4ntxo0y	181	18	Ecuador	Ecuador	NNP
cord-293701-u4ntxo0y	181	19	,	,	,
cord-293701-u4ntxo0y	181	20	showed	show	VBD
cord-293701-u4ntxo0y	181	21	severer	severe	JJR
cord-293701-u4ntxo0y	181	22	symptoms	symptom	NNS
cord-293701-u4ntxo0y	181	23	in	in	IN
cord-293701-u4ntxo0y	181	24	the	the	DT
cord-293701-u4ntxo0y	181	25	second	second	JJ
cord-293701-u4ntxo0y	181	26	round	round	NN
cord-293701-u4ntxo0y	181	27	of	of	IN
cord-293701-u4ntxo0y	181	28	infection	infection	NN
cord-293701-u4ntxo0y	181	29	103	103	CD
cord-293701-u4ntxo0y	181	30	,	,	,
cord-293701-u4ntxo0y	181	31	104	104	CD
cord-293701-u4ntxo0y	181	32	,	,	,
cord-293701-u4ntxo0y	181	33	whereas	whereas	IN
cord-293701-u4ntxo0y	181	34	two	two	CD
cord-293701-u4ntxo0y	181	35	reinfection	reinfection	NN
cord-293701-u4ntxo0y	181	36	cases	case	NNS
cord-293701-u4ntxo0y	181	37	in	in	IN
cord-293701-u4ntxo0y	181	38	Hong	Hong	NNP
cord-293701-u4ntxo0y	181	39	Kong	Kong	NNP
cord-293701-u4ntxo0y	181	40	and	and	CC
cord-293701-u4ntxo0y	181	41	Europe	Europe	NNP
cord-293701-u4ntxo0y	181	42	showed	show	VBD
cord-293701-u4ntxo0y	181	43	milder	mild	JJR
cord-293701-u4ntxo0y	181	44	symptoms	symptom	NNS
cord-293701-u4ntxo0y	181	45	in	in	IN
cord-293701-u4ntxo0y	181	46	the	the	DT
cord-293701-u4ntxo0y	181	47	second	second	JJ
cord-293701-u4ntxo0y	181	48	round	round	NN
cord-293701-u4ntxo0y	181	49	105	105	CD
cord-293701-u4ntxo0y	181	50	,	,	,
cord-293701-u4ntxo0y	181	51	106	106	CD
cord-293701-u4ntxo0y	181	52	.	.	.
cord-293701-u4ntxo0y	182	1	Notably	notably	RB
cord-293701-u4ntxo0y	182	2	,	,	,
cord-293701-u4ntxo0y	182	3	the	the	DT
cord-293701-u4ntxo0y	182	4	first	first	JJ
cord-293701-u4ntxo0y	182	5	round	round	NN
cord-293701-u4ntxo0y	182	6	of	of	IN
cord-293701-u4ntxo0y	182	7	infection	infection	NN
cord-293701-u4ntxo0y	182	8	did	do	VBD
cord-293701-u4ntxo0y	182	9	not	not	RB
cord-293701-u4ntxo0y	182	10	elicit	elicit	VB
cord-293701-u4ntxo0y	182	11	seroconversion	seroconversion	NN
cord-293701-u4ntxo0y	182	12	in	in	IN
cord-293701-u4ntxo0y	182	13	the	the	DT
cord-293701-u4ntxo0y	182	14	patient	patient	NN
cord-293701-u4ntxo0y	182	15	in	in	IN
cord-293701-u4ntxo0y	182	16	Hong	Hong	NNP
cord-293701-u4ntxo0y	182	17	Kong	Kong	NNP
cord-293701-u4ntxo0y	182	18	,	,	,
cord-293701-u4ntxo0y	182	19	which	which	WDT
cord-293701-u4ntxo0y	182	20	may	may	MD
cord-293701-u4ntxo0y	182	21	be	be	VB
cord-293701-u4ntxo0y	182	22	the	the	DT
cord-293701-u4ntxo0y	182	23	most	most	RBS
cord-293701-u4ntxo0y	182	24	critical	critical	JJ
cord-293701-u4ntxo0y	182	25	determinant	determinant	NN
cord-293701-u4ntxo0y	182	26	of	of	IN
cord-293701-u4ntxo0y	182	27	the	the	DT
cord-293701-u4ntxo0y	182	28	second	second	JJ
cord-293701-u4ntxo0y	182	29	round	round	NN
cord-293701-u4ntxo0y	182	30	of	of	IN
cord-293701-u4ntxo0y	182	31	infection	infection	NN
cord-293701-u4ntxo0y	182	32	.	.	.
cord-293701-u4ntxo0y	183	1	In	in	IN
cord-293701-u4ntxo0y	183	2	conclusion	conclusion	NN
cord-293701-u4ntxo0y	183	3	,	,	,
cord-293701-u4ntxo0y	183	4	we	-PRON-	PRP
cord-293701-u4ntxo0y	183	5	still	still	RB
cord-293701-u4ntxo0y	183	6	do	do	VBP
cord-293701-u4ntxo0y	183	7	not	not	RB
cord-293701-u4ntxo0y	183	8	fully	fully	RB
cord-293701-u4ntxo0y	183	9	understand	understand	VB
cord-293701-u4ntxo0y	183	10	the	the	DT
cord-293701-u4ntxo0y	183	11	antibody	antibody	NN
cord-293701-u4ntxo0y	183	12	dynamics	dynamic	NNS
cord-293701-u4ntxo0y	183	13	of	of	IN
cord-293701-u4ntxo0y	183	14	patients	patient	NNS
cord-293701-u4ntxo0y	183	15	with	with	IN
cord-293701-u4ntxo0y	183	16	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	183	17	,	,	,
cord-293701-u4ntxo0y	183	18	and	and	CC
cord-293701-u4ntxo0y	183	19	that	that	DT
cord-293701-u4ntxo0y	183	20	is	be	VBZ
cord-293701-u4ntxo0y	183	21	why	why	WRB
cord-293701-u4ntxo0y	183	22	we	-PRON-	PRP
cord-293701-u4ntxo0y	183	23	need	need	VBP
cord-293701-u4ntxo0y	183	24	to	to	TO
cord-293701-u4ntxo0y	183	25	carefully	carefully	RB
cord-293701-u4ntxo0y	183	26	assess	assess	VB
cord-293701-u4ntxo0y	183	27	the	the	DT
cord-293701-u4ntxo0y	183	28	immune	immune	JJ
cord-293701-u4ntxo0y	183	29	responses	response	NNS
cord-293701-u4ntxo0y	183	30	of	of	IN
cord-293701-u4ntxo0y	183	31	vaccine	vaccine	NN
cord-293701-u4ntxo0y	183	32	candidates	candidate	NNS
cord-293701-u4ntxo0y	183	33	in	in	IN
cord-293701-u4ntxo0y	183	34	animal	animal	NN
cord-293701-u4ntxo0y	183	35	models	model	NNS
cord-293701-u4ntxo0y	183	36	and	and	CC
cord-293701-u4ntxo0y	183	37	clinical	clinical	JJ
cord-293701-u4ntxo0y	183	38	trials	trial	NNS
cord-293701-u4ntxo0y	183	39	,	,	,
cord-293701-u4ntxo0y	183	40	which	which	WDT
cord-293701-u4ntxo0y	183	41	is	be	VBZ
cord-293701-u4ntxo0y	183	42	discussed	discuss	VBN
cord-293701-u4ntxo0y	183	43	next	next	RB
cord-293701-u4ntxo0y	183	44	.	.	.
cord-293701-u4ntxo0y	184	1	A	a	DT
cord-293701-u4ntxo0y	184	2	vaccine	vaccine	NN
cord-293701-u4ntxo0y	184	3	should	should	MD
cord-293701-u4ntxo0y	184	4	be	be	VB
cord-293701-u4ntxo0y	184	5	highly	highly	RB
cord-293701-u4ntxo0y	184	6	effective	effective	JJ
cord-293701-u4ntxo0y	184	7	in	in	IN
cord-293701-u4ntxo0y	184	8	triggering	trigger	VBG
cord-293701-u4ntxo0y	184	9	humoral	humoral	JJ
cord-293701-u4ntxo0y	184	10	and	and	CC
cord-293701-u4ntxo0y	184	11	cellular	cellular	JJ
cord-293701-u4ntxo0y	184	12	responses	response	NNS
cord-293701-u4ntxo0y	184	13	in	in	IN
cord-293701-u4ntxo0y	184	14	vivo	vivo	NN
cord-293701-u4ntxo0y	184	15	because	because	IN
cord-293701-u4ntxo0y	184	16	low	low	JJ
cord-293701-u4ntxo0y	184	17	titres	titre	NNS
cord-293701-u4ntxo0y	184	18	of	of	IN
cord-293701-u4ntxo0y	184	19	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	184	20	58	58	CD
cord-293701-u4ntxo0y	184	21	and	and	CC
cord-293701-u4ntxo0y	184	22	deficient	deficient	JJ
cord-293701-u4ntxo0y	184	23	activation	activation	NN
cord-293701-u4ntxo0y	184	24	of	of	IN
cord-293701-u4ntxo0y	184	25	CD8	CD8	NNP
cord-293701-u4ntxo0y	184	26	+	+	CC
cord-293701-u4ntxo0y	184	27	T	T	NNP
cord-293701-u4ntxo0y	184	28	cells	cell	NNS
cord-293701-u4ntxo0y	184	29	12	12	CD
cord-293701-u4ntxo0y	184	30	are	be	VBP
cord-293701-u4ntxo0y	184	31	both	both	DT
cord-293701-u4ntxo0y	184	32	risk	risk	NN
cord-293701-u4ntxo0y	184	33	factors	factor	NNS
cord-293701-u4ntxo0y	184	34	for	for	IN
cord-293701-u4ntxo0y	184	35	VADE	VADE	NNP
cord-293701-u4ntxo0y	184	36	.	.	.
cord-293701-u4ntxo0y	185	1	Meanwhile	meanwhile	RB
cord-293701-u4ntxo0y	185	2	,	,	,
cord-293701-u4ntxo0y	185	3	we	-PRON-	PRP
cord-293701-u4ntxo0y	185	4	see	see	VBP
cord-293701-u4ntxo0y	185	5	two	two	CD
cord-293701-u4ntxo0y	185	6	major	major	JJ
cord-293701-u4ntxo0y	185	7	barriers	barrier	NNS
cord-293701-u4ntxo0y	185	8	for	for	IN
cord-293701-u4ntxo0y	185	9	the	the	DT
cord-293701-u4ntxo0y	185	10	evaluation	evaluation	NN
cord-293701-u4ntxo0y	185	11	of	of	IN
cord-293701-u4ntxo0y	185	12	safety	safety	NN
cord-293701-u4ntxo0y	185	13	.	.	.
cord-293701-u4ntxo0y	186	1	First	first	RB
cord-293701-u4ntxo0y	186	2	,	,	,
cord-293701-u4ntxo0y	186	3	it	-PRON-	PRP
cord-293701-u4ntxo0y	186	4	usually	usually	RB
cord-293701-u4ntxo0y	186	5	takes	take	VBZ
cord-293701-u4ntxo0y	186	6	a	a	DT
cord-293701-u4ntxo0y	186	7	long	long	JJ
cord-293701-u4ntxo0y	186	8	time	time	NN
cord-293701-u4ntxo0y	186	9	to	to	TO
cord-293701-u4ntxo0y	186	10	observe	observe	VB
cord-293701-u4ntxo0y	186	11	VADE	VADE	NNP
cord-293701-u4ntxo0y	186	12	because	because	IN
cord-293701-u4ntxo0y	186	13	it	-PRON-	PRP
cord-293701-u4ntxo0y	186	14	appears	appear	VBZ
cord-293701-u4ntxo0y	186	15	mainly	mainly	RB
cord-293701-u4ntxo0y	186	16	in	in	IN
cord-293701-u4ntxo0y	186	17	subsequent	subsequent	JJ
cord-293701-u4ntxo0y	186	18	challenge	challenge	NN
cord-293701-u4ntxo0y	186	19	or	or	CC
cord-293701-u4ntxo0y	186	20	natural	natural	JJ
cord-293701-u4ntxo0y	186	21	infection	infection	NN
cord-293701-u4ntxo0y	186	22	,	,	,
cord-293701-u4ntxo0y	186	23	by	by	IN
cord-293701-u4ntxo0y	186	24	homologous	homologous	JJ
cord-293701-u4ntxo0y	186	25	or	or	CC
cord-293701-u4ntxo0y	186	26	heterologous	heterologous	JJ
cord-293701-u4ntxo0y	186	27	viral	viral	JJ
cord-293701-u4ntxo0y	186	28	strains	strain	NNS
cord-293701-u4ntxo0y	186	29	,	,	,
cord-293701-u4ntxo0y	186	30	and	and	CC
cord-293701-u4ntxo0y	186	31	the	the	DT
cord-293701-u4ntxo0y	186	32	occurrence	occurrence	NN
cord-293701-u4ntxo0y	186	33	is	be	VBZ
cord-293701-u4ntxo0y	186	34	often	often	RB
cord-293701-u4ntxo0y	186	35	related	relate	VBN
cord-293701-u4ntxo0y	186	36	to	to	IN
cord-293701-u4ntxo0y	186	37	antibody	antibody	NN
cord-293701-u4ntxo0y	186	38	titres	titre	NNS
cord-293701-u4ntxo0y	186	39	that	that	WDT
cord-293701-u4ntxo0y	186	40	have	have	VBP
cord-293701-u4ntxo0y	186	41	decreased	decrease	VBN
cord-293701-u4ntxo0y	186	42	to	to	IN
cord-293701-u4ntxo0y	186	43	suboptimal	suboptimal	JJ
cord-293701-u4ntxo0y	186	44	levels	level	NNS
cord-293701-u4ntxo0y	186	45	47	47	CD
cord-293701-u4ntxo0y	186	46	.	.	.
cord-293701-u4ntxo0y	187	1	Second	second	RB
cord-293701-u4ntxo0y	187	2	,	,	,
cord-293701-u4ntxo0y	187	3	it	-PRON-	PRP
cord-293701-u4ntxo0y	187	4	is	be	VBZ
cord-293701-u4ntxo0y	187	5	unclear	unclear	JJ
cord-293701-u4ntxo0y	187	6	whether	whether	IN
cord-293701-u4ntxo0y	187	7	experimental	experimental	JJ
cord-293701-u4ntxo0y	187	8	animals	animal	NNS
cord-293701-u4ntxo0y	187	9	accurately	accurately	RB
cord-293701-u4ntxo0y	187	10	represent	represent	VBP
cord-293701-u4ntxo0y	187	11	human	human	JJ
cord-293701-u4ntxo0y	187	12	responses	response	NNS
cord-293701-u4ntxo0y	187	13	.	.	.
cord-293701-u4ntxo0y	188	1	From	from	IN
cord-293701-u4ntxo0y	188	2	the	the	DT
cord-293701-u4ntxo0y	188	3	experience	experience	NN
cord-293701-u4ntxo0y	188	4	and	and	CC
cord-293701-u4ntxo0y	188	5	lessons	lesson	NNS
cord-293701-u4ntxo0y	188	6	derived	derive	VBN
cord-293701-u4ntxo0y	188	7	from	from	IN
cord-293701-u4ntxo0y	188	8	past	past	JJ
cord-293701-u4ntxo0y	188	9	development	development	NN
cord-293701-u4ntxo0y	188	10	of	of	IN
cord-293701-u4ntxo0y	188	11	RSV	RSV	NNP
cord-293701-u4ntxo0y	188	12	,	,	,
cord-293701-u4ntxo0y	188	13	dengue	dengue	NN
cord-293701-u4ntxo0y	188	14	,	,	,
cord-293701-u4ntxo0y	188	15	SARS	SARS	NNP
cord-293701-u4ntxo0y	188	16	and	and	CC
cord-293701-u4ntxo0y	188	17	MERS	MERS	NNP
cord-293701-u4ntxo0y	188	18	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	188	19	,	,	,
cord-293701-u4ntxo0y	188	20	we	-PRON-	PRP
cord-293701-u4ntxo0y	188	21	offer	offer	VBP
cord-293701-u4ntxo0y	188	22	the	the	DT
cord-293701-u4ntxo0y	188	23	following	follow	VBG
cord-293701-u4ntxo0y	188	24	recommendations	recommendation	NNS
cord-293701-u4ntxo0y	188	25	to	to	IN
cord-293701-u4ntxo0y	188	26	developers	developer	NNS
cord-293701-u4ntxo0y	188	27	of	of	IN
cord-293701-u4ntxo0y	188	28	a	a	DT
cord-293701-u4ntxo0y	188	29	safe	safe	JJ
cord-293701-u4ntxo0y	188	30	and	and	CC
cord-293701-u4ntxo0y	188	31	effective	effective	JJ
cord-293701-u4ntxo0y	188	32	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	188	33	vaccine	vaccine	NN
cord-293701-u4ntxo0y	188	34	.	.	.
cord-293701-u4ntxo0y	189	1	First	first	RB
cord-293701-u4ntxo0y	189	2	,	,	,
cord-293701-u4ntxo0y	189	3	the	the	DT
cord-293701-u4ntxo0y	189	4	safety	safety	NN
cord-293701-u4ntxo0y	189	5	of	of	IN
cord-293701-u4ntxo0y	189	6	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	189	7	vaccine	vaccine	NN
cord-293701-u4ntxo0y	189	8	candidates	candidate	NNS
cord-293701-u4ntxo0y	189	9	should	should	MD
cord-293701-u4ntxo0y	189	10	be	be	VB
cord-293701-u4ntxo0y	189	11	evaluated	evaluate	VBN
cord-293701-u4ntxo0y	189	12	in	in	IN
cord-293701-u4ntxo0y	189	13	diverse	diverse	JJ
cord-293701-u4ntxo0y	189	14	animal	animal	NN
cord-293701-u4ntxo0y	189	15	models	model	NNS
cord-293701-u4ntxo0y	189	16	.	.	.
cord-293701-u4ntxo0y	190	1	As	as	IN
cord-293701-u4ntxo0y	190	2	no	no	DT
cord-293701-u4ntxo0y	190	3	animal	animal	NN
cord-293701-u4ntxo0y	190	4	model	model	NN
cord-293701-u4ntxo0y	190	5	can	can	MD
cord-293701-u4ntxo0y	190	6	accurately	accurately	RB
cord-293701-u4ntxo0y	190	7	mimic	mimic	VB
cord-293701-u4ntxo0y	190	8	the	the	DT
cord-293701-u4ntxo0y	190	9	human	human	JJ
cord-293701-u4ntxo0y	190	10	immune	immune	JJ
cord-293701-u4ntxo0y	190	11	response	response	NN
cord-293701-u4ntxo0y	190	12	to	to	IN
cord-293701-u4ntxo0y	190	13	vaccine	vaccine	NN
cord-293701-u4ntxo0y	190	14	candidates	candidate	NNS
cord-293701-u4ntxo0y	190	15	,	,	,
cord-293701-u4ntxo0y	190	16	evaluation	evaluation	NN
cord-293701-u4ntxo0y	190	17	in	in	IN
cord-293701-u4ntxo0y	190	18	several	several	JJ
cord-293701-u4ntxo0y	190	19	animal	animal	NN
cord-293701-u4ntxo0y	190	20	models	model	NNS
cord-293701-u4ntxo0y	190	21	could	could	MD
cord-293701-u4ntxo0y	190	22	avoid	avoid	VB
cord-293701-u4ntxo0y	190	23	the	the	DT
cord-293701-u4ntxo0y	190	24	risk	risk	NN
cord-293701-u4ntxo0y	190	25	of	of	IN
cord-293701-u4ntxo0y	190	26	missing	miss	VBG
cord-293701-u4ntxo0y	190	27	pathogenic	pathogenic	JJ
cord-293701-u4ntxo0y	190	28	responses	response	NNS
cord-293701-u4ntxo0y	190	29	.	.	.
cord-293701-u4ntxo0y	191	1	Second	second	JJ
cord-293701-u4ntxo0y	191	2	,	,	,
cord-293701-u4ntxo0y	191	3	challenge	challenge	NN
cord-293701-u4ntxo0y	191	4	with	with	IN
cord-293701-u4ntxo0y	191	5	heterogeneous	heterogeneous	JJ
cord-293701-u4ntxo0y	191	6	viral	viral	JJ
cord-293701-u4ntxo0y	191	7	strains	strain	NNS
cord-293701-u4ntxo0y	191	8	should	should	MD
cord-293701-u4ntxo0y	191	9	be	be	VB
cord-293701-u4ntxo0y	191	10	applied	apply	VBN
cord-293701-u4ntxo0y	191	11	in	in	IN
cord-293701-u4ntxo0y	191	12	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	191	13	vaccine	vaccine	NN
cord-293701-u4ntxo0y	191	14	evaluations	evaluation	NNS
cord-293701-u4ntxo0y	191	15	with	with	IN
cord-293701-u4ntxo0y	191	16	antibodies	antibody	NNS
cord-293701-u4ntxo0y	191	17	cross	cross	VBP
cord-293701-u4ntxo0y	191	18	-	-	JJ
cord-293701-u4ntxo0y	191	19	reactive	reactive	JJ
cord-293701-u4ntxo0y	191	20	to	to	IN
cord-293701-u4ntxo0y	191	21	SARS	SARS	NNP
cord-293701-u4ntxo0y	191	22	-	-	HYPH
cord-293701-u4ntxo0y	191	23	CoV	CoV	NNP
cord-293701-u4ntxo0y	191	24	and	and	CC
cord-293701-u4ntxo0y	191	25	SARS	SARS	NNP
cord-293701-u4ntxo0y	191	26	-	-	HYPH
cord-293701-u4ntxo0y	191	27	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	191	28	(	(	-LRB-
cord-293701-u4ntxo0y	191	29	ref	ref	NN
cord-293701-u4ntxo0y	191	30	.	.	.
cord-293701-u4ntxo0y	192	1	107	107	LS
cord-293701-u4ntxo0y	192	2	)	)	-RRB-
cord-293701-u4ntxo0y	192	3	.	.	.
cord-293701-u4ntxo0y	193	1	Third	third	JJ
cord-293701-u4ntxo0y	193	2	,	,	,
cord-293701-u4ntxo0y	193	3	experiments	experiment	NNS
cord-293701-u4ntxo0y	193	4	should	should	MD
cord-293701-u4ntxo0y	193	5	be	be	VB
cord-293701-u4ntxo0y	193	6	repeated	repeat	VBN
cord-293701-u4ntxo0y	193	7	in	in	IN
cord-293701-u4ntxo0y	193	8	the	the	DT
cord-293701-u4ntxo0y	193	9	same	same	JJ
cord-293701-u4ntxo0y	193	10	animal	animal	NN
cord-293701-u4ntxo0y	193	11	model	model	NN
cord-293701-u4ntxo0y	193	12	at	at	IN
cord-293701-u4ntxo0y	193	13	different	different	JJ
cord-293701-u4ntxo0y	193	14	ages	age	NNS
cord-293701-u4ntxo0y	193	15	.	.	.
cord-293701-u4ntxo0y	194	1	Previous	previous	JJ
cord-293701-u4ntxo0y	194	2	studies	study	NNS
cord-293701-u4ntxo0y	194	3	proved	prove	VBD
cord-293701-u4ntxo0y	194	4	that	that	IN
cord-293701-u4ntxo0y	194	5	dengue	dengue	NN
cord-293701-u4ntxo0y	194	6	vaccine	vaccine	NN
cord-293701-u4ntxo0y	194	7	performance	performance	NN
cord-293701-u4ntxo0y	194	8	and	and	CC
cord-293701-u4ntxo0y	194	9	efficacy	efficacy	NN
cord-293701-u4ntxo0y	194	10	could	could	MD
cord-293701-u4ntxo0y	194	11	be	be	VB
cord-293701-u4ntxo0y	194	12	influenced	influence	VBN
cord-293701-u4ntxo0y	194	13	by	by	IN
cord-293701-u4ntxo0y	194	14	serotype	serotype	NN
cord-293701-u4ntxo0y	194	15	,	,	,
cord-293701-u4ntxo0y	194	16	baseline	baseline	JJ
cord-293701-u4ntxo0y	194	17	serostatus	serostatus	NN
cord-293701-u4ntxo0y	194	18	and	and	CC
cord-293701-u4ntxo0y	194	19	age	age	NN
cord-293701-u4ntxo0y	194	20	63	63	CD
cord-293701-u4ntxo0y	194	21	,	,	,
cord-293701-u4ntxo0y	194	22	68	68	CD
cord-293701-u4ntxo0y	194	23	.	.	.
cord-293701-u4ntxo0y	195	1	T	T	NNP
cord-293701-u4ntxo0y	195	2	H	h	NN
cord-293701-u4ntxo0y	195	3	2	2	CD
cord-293701-u4ntxo0y	195	4	cell	cell	NN
cord-293701-u4ntxo0y	195	5	-	-	HYPH
cord-293701-u4ntxo0y	195	6	biased	bias	VBN
cord-293701-u4ntxo0y	195	7	immunopathology	immunopathology	NN
cord-293701-u4ntxo0y	195	8	was	be	VBD
cord-293701-u4ntxo0y	195	9	observed	observe	VBN
cord-293701-u4ntxo0y	195	10	mainly	mainly	RB
cord-293701-u4ntxo0y	195	11	in	in	IN
cord-293701-u4ntxo0y	195	12	ageing	age	VBG
cord-293701-u4ntxo0y	195	13	mice	mouse	NNS
cord-293701-u4ntxo0y	195	14	immunized	immunize	VBN
cord-293701-u4ntxo0y	195	15	with	with	IN
cord-293701-u4ntxo0y	195	16	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	195	17	SARS	SARS	NNP
cord-293701-u4ntxo0y	195	18	-	-	HYPH
cord-293701-u4ntxo0y	195	19	CoV	CoV	NNP
cord-293701-u4ntxo0y	195	20	and	and	CC
cord-293701-u4ntxo0y	195	21	alum	alum	NN
cord-293701-u4ntxo0y	195	22	adjuvant	adjuvant	NNP
cord-293701-u4ntxo0y	195	23	76	76	CD
cord-293701-u4ntxo0y	195	24	.	.	.
cord-293701-u4ntxo0y	196	1	Venezuelan	venezuelan	JJ
cord-293701-u4ntxo0y	196	2	equine	equine	NN
cord-293701-u4ntxo0y	196	3	encephalitis	encephalitis	NN
cord-293701-u4ntxo0y	196	4	virus	virus	NN
cord-293701-u4ntxo0y	196	5	replicon	replicon	NN
cord-293701-u4ntxo0y	196	6	particles	particle	NNS
cord-293701-u4ntxo0y	196	7	expressing	express	VBG
cord-293701-u4ntxo0y	196	8	SARS	SARS	NNP
cord-293701-u4ntxo0y	196	9	-	-	HYPH
cord-293701-u4ntxo0y	196	10	CoV	CoV	NNP
cord-293701-u4ntxo0y	196	11	S	S	NNP
cord-293701-u4ntxo0y	196	12	protein	protein	NN
cord-293701-u4ntxo0y	196	13	provided	provide	VBD
cord-293701-u4ntxo0y	196	14	complete	complete	JJ
cord-293701-u4ntxo0y	196	15	short	short	JJ
cord-293701-u4ntxo0y	196	16	-	-	HYPH
cord-293701-u4ntxo0y	196	17	term	term	NN
cord-293701-u4ntxo0y	196	18	protection	protection	NN
cord-293701-u4ntxo0y	196	19	against	against	IN
cord-293701-u4ntxo0y	196	20	heterologous	heterologous	NNP
cord-293701-u4ntxo0y	196	21	SARS	SARS	NNP
cord-293701-u4ntxo0y	196	22	-	-	HYPH
cord-293701-u4ntxo0y	196	23	CoV	CoV	NNP
cord-293701-u4ntxo0y	196	24	challenge	challenge	NN
cord-293701-u4ntxo0y	196	25	in	in	IN
cord-293701-u4ntxo0y	196	26	young	young	JJ
cord-293701-u4ntxo0y	196	27	mice	mouse	NNS
cord-293701-u4ntxo0y	196	28	,	,	,
cord-293701-u4ntxo0y	196	29	whereas	whereas	IN
cord-293701-u4ntxo0y	196	30	only	only	RB
cord-293701-u4ntxo0y	196	31	limited	limited	JJ
cord-293701-u4ntxo0y	196	32	protection	protection	NN
cord-293701-u4ntxo0y	196	33	was	be	VBD
cord-293701-u4ntxo0y	196	34	seen	see	VBN
cord-293701-u4ntxo0y	196	35	in	in	IN
cord-293701-u4ntxo0y	196	36	vaccinated	vaccinated	JJ
cord-293701-u4ntxo0y	196	37	senescent	senescent	JJ
cord-293701-u4ntxo0y	196	38	animals	animal	NNS
cord-293701-u4ntxo0y	196	39	108	108	CD
cord-293701-u4ntxo0y	196	40	.	.	.
cord-293701-u4ntxo0y	197	1	Given	give	VBN
cord-293701-u4ntxo0y	197	2	that	that	IN
cord-293701-u4ntxo0y	197	3	older	old	JJR
cord-293701-u4ntxo0y	197	4	individuals	individual	NNS
cord-293701-u4ntxo0y	197	5	are	be	VBP
cord-293701-u4ntxo0y	197	6	the	the	DT
cord-293701-u4ntxo0y	197	7	population	population	NN
cord-293701-u4ntxo0y	197	8	most	most	RBS
cord-293701-u4ntxo0y	197	9	vulnerable	vulnerable	JJ
cord-293701-u4ntxo0y	197	10	to	to	IN
cord-293701-u4ntxo0y	197	11	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	197	12	,	,	,
cord-293701-u4ntxo0y	197	13	safety	safety	NN
cord-293701-u4ntxo0y	197	14	and	and	CC
cord-293701-u4ntxo0y	197	15	efficacy	efficacy	NN
cord-293701-u4ntxo0y	197	16	assessment	assessment	NN
cord-293701-u4ntxo0y	197	17	in	in	IN
cord-293701-u4ntxo0y	197	18	ageing	age	VBG
cord-293701-u4ntxo0y	197	19	animal	animal	NN
cord-293701-u4ntxo0y	197	20	models	model	NNS
cord-293701-u4ntxo0y	197	21	and	and	CC
cord-293701-u4ntxo0y	197	22	humans	human	NNS
cord-293701-u4ntxo0y	197	23	is	be	VBZ
cord-293701-u4ntxo0y	197	24	essential	essential	JJ
cord-293701-u4ntxo0y	197	25	.	.	.
cord-293701-u4ntxo0y	198	1	Fourth	fourth	RB
cord-293701-u4ntxo0y	198	2	,	,	,
cord-293701-u4ntxo0y	198	3	animal	animal	NN
cord-293701-u4ntxo0y	198	4	experiments	experiment	NNS
cord-293701-u4ntxo0y	198	5	and	and	CC
cord-293701-u4ntxo0y	198	6	clinical	clinical	JJ
cord-293701-u4ntxo0y	198	7	trials	trial	NNS
cord-293701-u4ntxo0y	198	8	should	should	MD
cord-293701-u4ntxo0y	198	9	also	also	RB
cord-293701-u4ntxo0y	198	10	be	be	VB
cord-293701-u4ntxo0y	198	11	performed	perform	VBN
cord-293701-u4ntxo0y	198	12	in	in	IN
cord-293701-u4ntxo0y	198	13	animal	animal	NN
cord-293701-u4ntxo0y	198	14	models	model	NNS
cord-293701-u4ntxo0y	198	15	and	and	CC
cord-293701-u4ntxo0y	198	16	humans	human	NNS
cord-293701-u4ntxo0y	198	17	with	with	IN
cord-293701-u4ntxo0y	198	18	co	co	NNS
cord-293701-u4ntxo0y	198	19	-	-	NNS
cord-293701-u4ntxo0y	198	20	morbidities	morbidity	NNS
cord-293701-u4ntxo0y	198	21	,	,	,
cord-293701-u4ntxo0y	198	22	considering	consider	VBG
cord-293701-u4ntxo0y	198	23	that	that	IN
cord-293701-u4ntxo0y	198	24	patients	patient	NNS
cord-293701-u4ntxo0y	198	25	with	with	IN
cord-293701-u4ntxo0y	198	26	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	198	27	with	with	IN
cord-293701-u4ntxo0y	198	28	co	co	NN
cord-293701-u4ntxo0y	198	29	-	-	NN
cord-293701-u4ntxo0y	198	30	morbidity	morbidity	NN
cord-293701-u4ntxo0y	198	31	were	be	VBD
cord-293701-u4ntxo0y	198	32	shown	show	VBN
cord-293701-u4ntxo0y	198	33	to	to	TO
cord-293701-u4ntxo0y	198	34	have	have	VB
cord-293701-u4ntxo0y	198	35	poorer	poor	JJR
cord-293701-u4ntxo0y	198	36	clinical	clinical	JJ
cord-293701-u4ntxo0y	198	37	outcomes	outcome	NNS
cord-293701-u4ntxo0y	198	38	than	than	IN
cord-293701-u4ntxo0y	198	39	those	those	DT
cord-293701-u4ntxo0y	198	40	without	without	IN
cord-293701-u4ntxo0y	198	41	,	,	,
cord-293701-u4ntxo0y	198	42	and	and	CC
cord-293701-u4ntxo0y	198	43	increasing	increase	VBG
cord-293701-u4ntxo0y	198	44	co	co	JJ
cord-293701-u4ntxo0y	198	45	-	-	NN
cord-293701-u4ntxo0y	198	46	morbidity	morbidity	JJ
cord-293701-u4ntxo0y	198	47	correlated	correlate	VBN
cord-293701-u4ntxo0y	198	48	with	with	IN
cord-293701-u4ntxo0y	198	49	much	much	RB
cord-293701-u4ntxo0y	198	50	poorer	poor	JJR
cord-293701-u4ntxo0y	198	51	clinical	clinical	JJ
cord-293701-u4ntxo0y	198	52	outcomes	outcome	NNS
cord-293701-u4ntxo0y	198	53	109	109	CD
cord-293701-u4ntxo0y	198	54	.	.	.
cord-293701-u4ntxo0y	199	1	Previously	previously	RB
cord-293701-u4ntxo0y	199	2	,	,	,
cord-293701-u4ntxo0y	199	3	several	several	JJ
cord-293701-u4ntxo0y	199	4	parameters	parameter	NNS
cord-293701-u4ntxo0y	199	5	were	be	VBD
cord-293701-u4ntxo0y	199	6	proposed	propose	VBN
cord-293701-u4ntxo0y	199	7	as	as	IN
cord-293701-u4ntxo0y	199	8	essential	essential	JJ
cord-293701-u4ntxo0y	199	9	in	in	IN
cord-293701-u4ntxo0y	199	10	the	the	DT
cord-293701-u4ntxo0y	199	11	evaluation	evaluation	NN
cord-293701-u4ntxo0y	199	12	of	of	IN
cord-293701-u4ntxo0y	199	13	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	199	14	vaccine	vaccine	NN
cord-293701-u4ntxo0y	199	15	safety	safety	NN
cord-293701-u4ntxo0y	199	16	and	and	CC
cord-293701-u4ntxo0y	199	17	efficacy	efficacy	NN
cord-293701-u4ntxo0y	199	18	,	,	,
cord-293701-u4ntxo0y	199	19	including	include	VBG
cord-293701-u4ntxo0y	199	20	the	the	DT
cord-293701-u4ntxo0y	199	21	geometric	geometric	JJ
cord-293701-u4ntxo0y	199	22	mean	mean	NN
cord-293701-u4ntxo0y	199	23	titre	titre	NN
cord-293701-u4ntxo0y	199	24	of	of	IN
cord-293701-u4ntxo0y	199	25	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	199	26	,	,	,
cord-293701-u4ntxo0y	199	27	the	the	DT
cord-293701-u4ntxo0y	199	28	ratio	ratio	NN
cord-293701-u4ntxo0y	199	29	of	of	IN
cord-293701-u4ntxo0y	199	30	NAb	NAb	NNP
cord-293701-u4ntxo0y	199	31	titre	titre	NN
cord-293701-u4ntxo0y	199	32	to	to	IN
cord-293701-u4ntxo0y	199	33	non	non	JJ
cord-293701-u4ntxo0y	199	34	-	-	JJ
cord-293701-u4ntxo0y	199	35	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	199	36	antibody	antibody	NN
cord-293701-u4ntxo0y	199	37	titre	titre	NN
cord-293701-u4ntxo0y	199	38	,	,	,
cord-293701-u4ntxo0y	199	39	antibody	antibody	NN
cord-293701-u4ntxo0y	199	40	affinity	affinity	NN
cord-293701-u4ntxo0y	199	41	,	,	,
cord-293701-u4ntxo0y	199	42	T	T	NNP
cord-293701-u4ntxo0y	199	43	cell	cell	NN
cord-293701-u4ntxo0y	199	44	response	response	NN
cord-293701-u4ntxo0y	199	45	profile	profile	NN
cord-293701-u4ntxo0y	199	46	,	,	,
cord-293701-u4ntxo0y	199	47	virus	virus	NN
cord-293701-u4ntxo0y	199	48	titres	titre	NNS
cord-293701-u4ntxo0y	199	49	in	in	IN
cord-293701-u4ntxo0y	199	50	the	the	DT
cord-293701-u4ntxo0y	199	51	upper	upper	JJ
cord-293701-u4ntxo0y	199	52	and	and	CC
cord-293701-u4ntxo0y	199	53	lower	low	JJR
cord-293701-u4ntxo0y	199	54	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	199	55	tract	tract	NN
cord-293701-u4ntxo0y	199	56	,	,	,
cord-293701-u4ntxo0y	199	57	and	and	CC
cord-293701-u4ntxo0y	199	58	characterization	characterization	NN
cord-293701-u4ntxo0y	199	59	of	of	IN
cord-293701-u4ntxo0y	199	60	lung	lung	NN
cord-293701-u4ntxo0y	199	61	histopathology	histopathology	NN
cord-293701-u4ntxo0y	199	62	with	with	IN
cord-293701-u4ntxo0y	199	63	immunohistochemistry	immunohistochemistry	NN
cord-293701-u4ntxo0y	199	64	for	for	IN
cord-293701-u4ntxo0y	199	65	viral	viral	JJ
cord-293701-u4ntxo0y	199	66	antigen	antigen	NN
cord-293701-u4ntxo0y	199	67	and	and	CC
cord-293701-u4ntxo0y	199	68	immune	immune	JJ
cord-293701-u4ntxo0y	199	69	cell	cell	NN
cord-293701-u4ntxo0y	199	70	markers	marker	NNS
cord-293701-u4ntxo0y	199	71	110	110	CD
cord-293701-u4ntxo0y	199	72	.	.	.
cord-293701-u4ntxo0y	200	1	The	the	DT
cord-293701-u4ntxo0y	200	2	titre	titre	NN
cord-293701-u4ntxo0y	200	3	of	of	IN
cord-293701-u4ntxo0y	200	4	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	200	5	induced	induce	VBN
cord-293701-u4ntxo0y	200	6	by	by	IN
cord-293701-u4ntxo0y	200	7	a	a	DT
cord-293701-u4ntxo0y	200	8	vaccine	vaccine	NN
cord-293701-u4ntxo0y	200	9	is	be	VBZ
cord-293701-u4ntxo0y	200	10	the	the	DT
cord-293701-u4ntxo0y	200	11	most	most	RBS
cord-293701-u4ntxo0y	200	12	important	important	JJ
cord-293701-u4ntxo0y	200	13	indicator	indicator	NN
cord-293701-u4ntxo0y	200	14	for	for	IN
cord-293701-u4ntxo0y	200	15	efficacy	efficacy	NN
cord-293701-u4ntxo0y	200	16	and	and	CC
cord-293701-u4ntxo0y	200	17	safety	safety	NN
cord-293701-u4ntxo0y	200	18	evaluation	evaluation	NN
cord-293701-u4ntxo0y	200	19	because	because	IN
cord-293701-u4ntxo0y	200	20	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	200	21	at	at	IN
cord-293701-u4ntxo0y	200	22	a	a	DT
cord-293701-u4ntxo0y	200	23	suboptimal	suboptimal	JJ
cord-293701-u4ntxo0y	200	24	concentration	concentration	NN
cord-293701-u4ntxo0y	200	25	do	do	VBP
cord-293701-u4ntxo0y	200	26	not	not	RB
cord-293701-u4ntxo0y	200	27	effectively	effectively	RB
cord-293701-u4ntxo0y	200	28	neutralize	neutralize	VB
cord-293701-u4ntxo0y	200	29	and	and	CC
cord-293701-u4ntxo0y	200	30	may	may	MD
cord-293701-u4ntxo0y	200	31	enhance	enhance	VB
cord-293701-u4ntxo0y	200	32	SARS	SARS	NNP
cord-293701-u4ntxo0y	200	33	-	-	HYPH
cord-293701-u4ntxo0y	200	34	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	200	35	infection	infection	NN
cord-293701-u4ntxo0y	200	36	111	111	CD
cord-293701-u4ntxo0y	200	37	.	.	.
cord-293701-u4ntxo0y	201	1	Moore	Moore	NNP
cord-293701-u4ntxo0y	201	2	and	and	CC
cord-293701-u4ntxo0y	201	3	Klasse	Klasse	NNP
cord-293701-u4ntxo0y	201	4	concluded	conclude	VBD
cord-293701-u4ntxo0y	201	5	in	in	IN
cord-293701-u4ntxo0y	201	6	a	a	DT
cord-293701-u4ntxo0y	201	7	review	review	NN
cord-293701-u4ntxo0y	201	8	that	that	IN
cord-293701-u4ntxo0y	201	9	"	"	``
cord-293701-u4ntxo0y	201	10	it	-PRON-	PRP
cord-293701-u4ntxo0y	201	11	is	be	VBZ
cord-293701-u4ntxo0y	201	12	not	not	RB
cord-293701-u4ntxo0y	201	13	known	know	VBN
cord-293701-u4ntxo0y	201	14	what	what	WDT
cord-293701-u4ntxo0y	201	15	benchmark	benchmark	NN
cord-293701-u4ntxo0y	201	16	serum	serum	NN
cord-293701-u4ntxo0y	201	17	antibody	antibody	NN
cord-293701-u4ntxo0y	201	18	and	and	CC
cord-293701-u4ntxo0y	201	19	NAb	nab	VBP
cord-293701-u4ntxo0y	201	20	titers	titer	NNS
cord-293701-u4ntxo0y	201	21	must	must	MD
cord-293701-u4ntxo0y	201	22	be	be	VB
cord-293701-u4ntxo0y	201	23	reached	reach	VBN
cord-293701-u4ntxo0y	201	24	for	for	IN
cord-293701-u4ntxo0y	201	25	a	a	DT
cord-293701-u4ntxo0y	201	26	SARS	SARS	NNP
cord-293701-u4ntxo0y	201	27	-	-	HYPH
cord-293701-u4ntxo0y	201	28	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	201	29	S	S	NNP
cord-293701-u4ntxo0y	201	30	-	-	HYPH
cord-293701-u4ntxo0y	201	31	protein	protein	NN
cord-293701-u4ntxo0y	201	32	vaccine	vaccine	NN
cord-293701-u4ntxo0y	201	33	to	to	TO
cord-293701-u4ntxo0y	201	34	protect	protect	VB
cord-293701-u4ntxo0y	201	35	humans	human	NNS
cord-293701-u4ntxo0y	201	36	.	.	.
cord-293701-u4ntxo0y	202	1	The	the	DT
cord-293701-u4ntxo0y	202	2	animal	animal	NN
cord-293701-u4ntxo0y	202	3	challenge	challenge	NN
cord-293701-u4ntxo0y	202	4	experiments	experiment	NNS
cord-293701-u4ntxo0y	202	5	reviewed	review	VBN
cord-293701-u4ntxo0y	202	6	above	above	RB
cord-293701-u4ntxo0y	202	7	suggest	suggest	VBP
cord-293701-u4ntxo0y	202	8	that	that	IN
cord-293701-u4ntxo0y	202	9	a	a	DT
cord-293701-u4ntxo0y	202	10	serum	serum	NN
cord-293701-u4ntxo0y	202	11	NAb	nab	NN
cord-293701-u4ntxo0y	202	12	ID	ID	NNP
cord-293701-u4ntxo0y	202	13	50	50	CD
cord-293701-u4ntxo0y	202	14	titer	titer	NN
cord-293701-u4ntxo0y	202	15	in	in	IN
cord-293701-u4ntxo0y	202	16	the	the	DT
cord-293701-u4ntxo0y	202	17	approximate	approximate	JJ
cord-293701-u4ntxo0y	202	18	range	range	NN
cord-293701-u4ntxo0y	202	19	of	of	IN
cord-293701-u4ntxo0y	202	20	100	100	CD
cord-293701-u4ntxo0y	202	21	to	to	TO
cord-293701-u4ntxo0y	202	22	500	500	CD
cord-293701-u4ntxo0y	202	23	is	be	VBZ
cord-293701-u4ntxo0y	202	24	required	require	VBN
cord-293701-u4ntxo0y	202	25	for	for	IN
cord-293701-u4ntxo0y	202	26	sterilizing	sterilize	VBG
cord-293701-u4ntxo0y	202	27	immunity	immunity	NN
cord-293701-u4ntxo0y	202	28	"	"	``
cord-293701-u4ntxo0y	202	29	112	112	CD
cord-293701-u4ntxo0y	202	30	.	.	.
cord-293701-u4ntxo0y	203	1	We	-PRON-	PRP
cord-293701-u4ntxo0y	203	2	also	also	RB
cord-293701-u4ntxo0y	203	3	noticed	notice	VBD
cord-293701-u4ntxo0y	203	4	an	an	DT
cord-293701-u4ntxo0y	203	5	absence	absence	NN
cord-293701-u4ntxo0y	203	6	of	of	IN
cord-293701-u4ntxo0y	203	7	detectable	detectable	JJ
cord-293701-u4ntxo0y	203	8	SARS	SARS	NNP
cord-293701-u4ntxo0y	203	9	-	-	HYPH
cord-293701-u4ntxo0y	203	10	CoV	CoV	NNP
cord-293701-u4ntxo0y	203	11	RNA	RNA	NNP
cord-293701-u4ntxo0y	203	12	in	in	IN
cord-293701-u4ntxo0y	203	13	lung	lung	NN
cord-293701-u4ntxo0y	203	14	tissues	tissue	NNS
cord-293701-u4ntxo0y	203	15	of	of	IN
cord-293701-u4ntxo0y	203	16	vaccinated	vaccinated	JJ
cord-293701-u4ntxo0y	203	17	mice	mouse	NNS
cord-293701-u4ntxo0y	203	18	with	with	IN
cord-293701-u4ntxo0y	203	19	serum	serum	NN
cord-293701-u4ntxo0y	203	20	NAb	NAb	NNS
cord-293701-u4ntxo0y	203	21	titres	titre	NNS
cord-293701-u4ntxo0y	203	22	of	of	IN
cord-293701-u4ntxo0y	203	23	1:189	1:189	CD
cord-293701-u4ntxo0y	203	24	or	or	CC
cord-293701-u4ntxo0y	203	25	higher	high	JJR
cord-293701-u4ntxo0y	203	26	113	113	CD
cord-293701-u4ntxo0y	203	27	.	.	.
cord-293701-u4ntxo0y	204	1	The	the	DT
cord-293701-u4ntxo0y	204	2	FDA	FDA	NNP
cord-293701-u4ntxo0y	204	3	recommended	recommend	VBD
cord-293701-u4ntxo0y	204	4	that	that	IN
cord-293701-u4ntxo0y	204	5	the	the	DT
cord-293701-u4ntxo0y	204	6	NAb	NAb	NNS
cord-293701-u4ntxo0y	204	7	titres	titre	NNS
cord-293701-u4ntxo0y	204	8	of	of	IN
cord-293701-u4ntxo0y	204	9	convalescent	convalescent	JJ
cord-293701-u4ntxo0y	204	10	plasma	plasma	NN
cord-293701-u4ntxo0y	204	11	for	for	IN
cord-293701-u4ntxo0y	204	12	passive	passive	JJ
cord-293701-u4ntxo0y	204	13	therapy	therapy	NN
cord-293701-u4ntxo0y	204	14	be	be	VB
cord-293701-u4ntxo0y	204	15	at	at	IN
cord-293701-u4ntxo0y	204	16	least	least	JJS
cord-293701-u4ntxo0y	204	17	1:160	1:160	CD
cord-293701-u4ntxo0y	204	18	(	(	-LRB-
cord-293701-u4ntxo0y	204	19	ref	ref	NN
cord-293701-u4ntxo0y	204	20	.	.	.
cord-293701-u4ntxo0y	204	21	114	114	CD
cord-293701-u4ntxo0y	204	22	)	)	-RRB-
cord-293701-u4ntxo0y	204	23	.	.	.
cord-293701-u4ntxo0y	205	1	Accordingly	accordingly	RB
cord-293701-u4ntxo0y	205	2	,	,	,
cord-293701-u4ntxo0y	205	3	we	-PRON-	PRP
cord-293701-u4ntxo0y	205	4	propose	propose	VBP
cord-293701-u4ntxo0y	205	5	that	that	IN
cord-293701-u4ntxo0y	205	6	an	an	DT
cord-293701-u4ntxo0y	205	7	effective	effective	JJ
cord-293701-u4ntxo0y	205	8	and	and	CC
cord-293701-u4ntxo0y	205	9	safe	safe	JJ
cord-293701-u4ntxo0y	205	10	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	205	11	vaccine	vaccine	NN
cord-293701-u4ntxo0y	205	12	should	should	MD
cord-293701-u4ntxo0y	205	13	be	be	VB
cord-293701-u4ntxo0y	205	14	able	able	JJ
cord-293701-u4ntxo0y	205	15	to	to	TO
cord-293701-u4ntxo0y	205	16	induce	induce	VB
cord-293701-u4ntxo0y	205	17	antiserum	antiserum	NN
cord-293701-u4ntxo0y	205	18	in	in	IN
cord-293701-u4ntxo0y	205	19	a	a	DT
cord-293701-u4ntxo0y	205	20	mouse	mouse	NN
cord-293701-u4ntxo0y	205	21	model	model	NN
cord-293701-u4ntxo0y	205	22	with	with	IN
cord-293701-u4ntxo0y	205	23	a	a	DT
cord-293701-u4ntxo0y	205	24	neutralization	neutralization	NN
cord-293701-u4ntxo0y	205	25	titre	titre	NN
cord-293701-u4ntxo0y	205	26	of	of	IN
cord-293701-u4ntxo0y	205	27	at	at	RB
cord-293701-u4ntxo0y	205	28	least	least	JJS
cord-293701-u4ntxo0y	205	29	1:160	1:160	CD
cord-293701-u4ntxo0y	205	30	against	against	IN
cord-293701-u4ntxo0y	205	31	live	live	JJ
cord-293701-u4ntxo0y	205	32	SARS	SARS	NNP
cord-293701-u4ntxo0y	205	33	-	-	HYPH
cord-293701-u4ntxo0y	205	34	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	205	35	infection	infection	NN
cord-293701-u4ntxo0y	205	36	.	.	.
cord-293701-u4ntxo0y	206	1	Enhanced	enhanced	JJ
cord-293701-u4ntxo0y	206	2	eosinophil	eosinophil	JJ
cord-293701-u4ntxo0y	206	3	filtration	filtration	NN
cord-293701-u4ntxo0y	206	4	in	in	IN
cord-293701-u4ntxo0y	206	5	the	the	DT
cord-293701-u4ntxo0y	206	6	lung	lung	NN
cord-293701-u4ntxo0y	206	7	is	be	VBZ
cord-293701-u4ntxo0y	206	8	one	one	CD
cord-293701-u4ntxo0y	206	9	of	of	IN
cord-293701-u4ntxo0y	206	10	the	the	DT
cord-293701-u4ntxo0y	206	11	strongest	strong	JJS
cord-293701-u4ntxo0y	206	12	indicators	indicator	NNS
cord-293701-u4ntxo0y	206	13	of	of	IN
cord-293701-u4ntxo0y	206	14	VADE	VADE	NNP
cord-293701-u4ntxo0y	206	15	caused	cause	VBN
cord-293701-u4ntxo0y	206	16	by	by	IN
cord-293701-u4ntxo0y	206	17	SARS	SARS	NNP
cord-293701-u4ntxo0y	206	18	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	206	19	[	[	-LRB-
cord-293701-u4ntxo0y	206	20	76	76	CD
cord-293701-u4ntxo0y	206	21	]	]	-RRB-
cord-293701-u4ntxo0y	206	22	[	[	-LRB-
cord-293701-u4ntxo0y	206	23	77	77	CD
cord-293701-u4ntxo0y	206	24	]	]	-RRB-
cord-293701-u4ntxo0y	206	25	[	[	-LRB-
cord-293701-u4ntxo0y	206	26	78	78	CD
cord-293701-u4ntxo0y	206	27	]	]	-RRB-
cord-293701-u4ntxo0y	206	28	or	or	CC
cord-293701-u4ntxo0y	206	29	MERS	MERS	NNP
cord-293701-u4ntxo0y	206	30	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	206	31	87	87	CD
cord-293701-u4ntxo0y	206	32	,	,	,
cord-293701-u4ntxo0y	206	33	88	88	CD
cord-293701-u4ntxo0y	206	34	,	,	,
cord-293701-u4ntxo0y	206	35	which	which	WDT
cord-293701-u4ntxo0y	206	36	should	should	MD
cord-293701-u4ntxo0y	206	37	also	also	RB
cord-293701-u4ntxo0y	206	38	be	be	VB
cord-293701-u4ntxo0y	206	39	monitored	monitor	VBN
cord-293701-u4ntxo0y	206	40	when	when	WRB
cord-293701-u4ntxo0y	206	41	one	one	CD
cord-293701-u4ntxo0y	206	42	is	be	VBZ
cord-293701-u4ntxo0y	206	43	evaluating	evaluate	VBG
cord-293701-u4ntxo0y	206	44	the	the	DT
cord-293701-u4ntxo0y	206	45	safety	safety	NN
cord-293701-u4ntxo0y	206	46	of	of	IN
cord-293701-u4ntxo0y	206	47	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	206	48	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	206	49	after	after	IN
cord-293701-u4ntxo0y	206	50	viral	viral	JJ
cord-293701-u4ntxo0y	206	51	challenge	challenge	NN
cord-293701-u4ntxo0y	206	52	or	or	CC
cord-293701-u4ntxo0y	206	53	natural	natural	JJ
cord-293701-u4ntxo0y	206	54	viral	viral	JJ
cord-293701-u4ntxo0y	206	55	infection	infection	NN
cord-293701-u4ntxo0y	206	56	.	.	.
cord-293701-u4ntxo0y	207	1	On	on	IN
cord-293701-u4ntxo0y	207	2	the	the	DT
cord-293701-u4ntxo0y	207	3	basis	basis	NN
cord-293701-u4ntxo0y	207	4	of	of	IN
cord-293701-u4ntxo0y	207	5	report	report	NN
cord-293701-u4ntxo0y	207	6	by	by	IN
cord-293701-u4ntxo0y	207	7	Chen	Chen	NNP
cord-293701-u4ntxo0y	207	8	et	et	NNP
cord-293701-u4ntxo0y	207	9	al	al	NNP
cord-293701-u4ntxo0y	207	10	.	.	.
cord-293701-u4ntxo0y	208	1	115	115	CD
cord-293701-u4ntxo0y	208	2	,	,	,
cord-293701-u4ntxo0y	208	3	the	the	DT
cord-293701-u4ntxo0y	208	4	eosinophil	eosinophil	JJ
cord-293701-u4ntxo0y	208	5	content	content	NN
cord-293701-u4ntxo0y	208	6	in	in	IN
cord-293701-u4ntxo0y	208	7	the	the	DT
cord-293701-u4ntxo0y	208	8	lung	lung	NN
cord-293701-u4ntxo0y	208	9	of	of	IN
cord-293701-u4ntxo0y	208	10	a	a	DT
cord-293701-u4ntxo0y	208	11	mouse	mouse	NN
cord-293701-u4ntxo0y	208	12	immunized	immunize	VBN
cord-293701-u4ntxo0y	208	13	with	with	IN
cord-293701-u4ntxo0y	208	14	a	a	DT
cord-293701-u4ntxo0y	208	15	safe	safe	JJ
cord-293701-u4ntxo0y	208	16	SARS	SARS	NNP
cord-293701-u4ntxo0y	208	17	vaccine	vaccine	NN
cord-293701-u4ntxo0y	208	18	should	should	MD
cord-293701-u4ntxo0y	208	19	be	be	VB
cord-293701-u4ntxo0y	208	20	less	less	JJR
cord-293701-u4ntxo0y	208	21	than	than	IN
cord-293701-u4ntxo0y	208	22	5	5	CD
cord-293701-u4ntxo0y	208	23	%	%	NN
cord-293701-u4ntxo0y	208	24	of	of	IN
cord-293701-u4ntxo0y	208	25	infiltrating	infiltrate	VBG
cord-293701-u4ntxo0y	208	26	cells	cell	NNS
cord-293701-u4ntxo0y	208	27	after	after	IN
cord-293701-u4ntxo0y	208	28	viral	viral	JJ
cord-293701-u4ntxo0y	208	29	challenge	challenge	NN
cord-293701-u4ntxo0y	208	30	.	.	.
cord-293701-u4ntxo0y	209	1	Accordingly	accordingly	RB
cord-293701-u4ntxo0y	209	2	,	,	,
cord-293701-u4ntxo0y	209	3	we	-PRON-	PRP
cord-293701-u4ntxo0y	209	4	propose	propose	VBP
cord-293701-u4ntxo0y	209	5	that	that	IN
cord-293701-u4ntxo0y	209	6	eosinophil	eosinophil	NN
cord-293701-u4ntxo0y	209	7	infiltrates	infiltrate	VBZ
cord-293701-u4ntxo0y	209	8	of	of	IN
cord-293701-u4ntxo0y	209	9	5	5	CD
cord-293701-u4ntxo0y	209	10	%	%	NN
cord-293701-u4ntxo0y	209	11	or	or	CC
cord-293701-u4ntxo0y	209	12	greater	great	JJR
cord-293701-u4ntxo0y	209	13	in	in	IN
cord-293701-u4ntxo0y	209	14	the	the	DT
cord-293701-u4ntxo0y	209	15	lung	lung	NN
cord-293701-u4ntxo0y	209	16	of	of	IN
cord-293701-u4ntxo0y	209	17	a	a	DT
cord-293701-u4ntxo0y	209	18	vaccinated	vaccinated	JJ
cord-293701-u4ntxo0y	209	19	mouse	mouse	NN
cord-293701-u4ntxo0y	209	20	after	after	IN
cord-293701-u4ntxo0y	209	21	viral	viral	JJ
cord-293701-u4ntxo0y	209	22	challenge	challenge	NN
cord-293701-u4ntxo0y	209	23	should	should	MD
cord-293701-u4ntxo0y	209	24	be	be	VB
cord-293701-u4ntxo0y	209	25	considered	consider	VBN
cord-293701-u4ntxo0y	209	26	as	as	IN
cord-293701-u4ntxo0y	209	27	a	a	DT
cord-293701-u4ntxo0y	209	28	putative	putative	JJ
cord-293701-u4ntxo0y	209	29	parameter	parameter	NN
cord-293701-u4ntxo0y	209	30	for	for	IN
cord-293701-u4ntxo0y	209	31	VADE	VADE	NNP
cord-293701-u4ntxo0y	209	32	.	.	.
cord-293701-u4ntxo0y	210	1	How	how	WRB
cord-293701-u4ntxo0y	210	2	long	long	JJ
cord-293701-u4ntxo0y	210	3	the	the	DT
cord-293701-u4ntxo0y	210	4	vaccine	vaccine	NN
cord-293701-u4ntxo0y	210	5	-	-	HYPH
cord-293701-u4ntxo0y	210	6	induced	induce	VBN
cord-293701-u4ntxo0y	210	7	NAb	NAb	NNP
cord-293701-u4ntxo0y	210	8	response	response	NN
cord-293701-u4ntxo0y	210	9	can	can	MD
cord-293701-u4ntxo0y	210	10	last	last	VB
cord-293701-u4ntxo0y	210	11	is	be	VBZ
cord-293701-u4ntxo0y	210	12	another	another	DT
cord-293701-u4ntxo0y	210	13	parameter	parameter	NN
cord-293701-u4ntxo0y	210	14	for	for	IN
cord-293701-u4ntxo0y	210	15	evaluation	evaluation	NN
cord-293701-u4ntxo0y	210	16	of	of	IN
cord-293701-u4ntxo0y	210	17	the	the	DT
cord-293701-u4ntxo0y	210	18	safety	safety	NN
cord-293701-u4ntxo0y	210	19	and	and	CC
cord-293701-u4ntxo0y	210	20	efficacy	efficacy	NN
cord-293701-u4ntxo0y	210	21	of	of	IN
cord-293701-u4ntxo0y	210	22	a	a	DT
cord-293701-u4ntxo0y	210	23	vaccine	vaccine	NN
cord-293701-u4ntxo0y	210	24	.	.	.
cord-293701-u4ntxo0y	211	1	Seow	Seow	NNP
cord-293701-u4ntxo0y	211	2	et	et	NNP
cord-293701-u4ntxo0y	211	3	al	al	NNP
cord-293701-u4ntxo0y	211	4	.	.	.
cord-293701-u4ntxo0y	212	1	recently	recently	RB
cord-293701-u4ntxo0y	212	2	reported	report	VBD
cord-293701-u4ntxo0y	212	3	that	that	IN
cord-293701-u4ntxo0y	212	4	the	the	DT
cord-293701-u4ntxo0y	212	5	NAb	NAb	NNS
cord-293701-u4ntxo0y	212	6	titre	titre	NN
cord-293701-u4ntxo0y	212	7	of	of	IN
cord-293701-u4ntxo0y	212	8	some	some	DT
cord-293701-u4ntxo0y	212	9	recovered	recover	VBN
cord-293701-u4ntxo0y	212	10	patients	patient	NNS
cord-293701-u4ntxo0y	212	11	with	with	IN
cord-293701-u4ntxo0y	212	12	a	a	DT
cord-293701-u4ntxo0y	212	13	lower	low	JJR
cord-293701-u4ntxo0y	212	14	peak	peak	NN
cord-293701-u4ntxo0y	212	15	titre	titre	NN
cord-293701-u4ntxo0y	212	16	waned	wane	VBD
cord-293701-u4ntxo0y	212	17	to	to	IN
cord-293701-u4ntxo0y	212	18	an	an	DT
cord-293701-u4ntxo0y	212	19	undetectable	undetectable	JJ
cord-293701-u4ntxo0y	212	20	level	level	NN
cord-293701-u4ntxo0y	212	21	in	in	IN
cord-293701-u4ntxo0y	212	22	2	2	CD
cord-293701-u4ntxo0y	212	23	-	-	SYM
cord-293701-u4ntxo0y	212	24	3	3	CD
cord-293701-u4ntxo0y	212	25	months	month	NNS
cord-293701-u4ntxo0y	212	26	116	116	CD
cord-293701-u4ntxo0y	212	27	,	,	,
cord-293701-u4ntxo0y	212	28	indicating	indicate	VBG
cord-293701-u4ntxo0y	212	29	that	that	IN
cord-293701-u4ntxo0y	212	30	the	the	DT
cord-293701-u4ntxo0y	212	31	duration	duration	NN
cord-293701-u4ntxo0y	212	32	of	of	IN
cord-293701-u4ntxo0y	212	33	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	212	34	may	may	MD
cord-293701-u4ntxo0y	212	35	not	not	RB
cord-293701-u4ntxo0y	212	36	be	be	VB
cord-293701-u4ntxo0y	212	37	long	long	JJ
cord-293701-u4ntxo0y	212	38	.	.	.
cord-293701-u4ntxo0y	213	1	By	by	IN
cord-293701-u4ntxo0y	213	2	contrast	contrast	NN
cord-293701-u4ntxo0y	213	3	,	,	,
cord-293701-u4ntxo0y	213	4	a	a	DT
cord-293701-u4ntxo0y	213	5	large	large	JJ
cord-293701-u4ntxo0y	213	6	-	-	HYPH
cord-293701-u4ntxo0y	213	7	scale	scale	NN
cord-293701-u4ntxo0y	213	8	study	study	NN
cord-293701-u4ntxo0y	213	9	in	in	IN
cord-293701-u4ntxo0y	213	10	Iceland	Iceland	NNP
cord-293701-u4ntxo0y	213	11	demonstrated	demonstrate	VBD
cord-293701-u4ntxo0y	213	12	that	that	IN
cord-293701-u4ntxo0y	213	13	antiviral	antiviral	JJ
cord-293701-u4ntxo0y	213	14	antibodies	antibody	NNS
cord-293701-u4ntxo0y	213	15	to	to	IN
cord-293701-u4ntxo0y	213	16	SARS	SARS	NNP
cord-293701-u4ntxo0y	213	17	-	-	HYPH
cord-293701-u4ntxo0y	213	18	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	213	19	could	could	MD
cord-293701-u4ntxo0y	213	20	last	last	VB
cord-293701-u4ntxo0y	213	21	for	for	IN
cord-293701-u4ntxo0y	213	22	at	at	RB
cord-293701-u4ntxo0y	213	23	least	least	JJS
cord-293701-u4ntxo0y	213	24	4	4	CD
cord-293701-u4ntxo0y	213	25	months	month	NNS
cord-293701-u4ntxo0y	213	26	117	117	CD
cord-293701-u4ntxo0y	213	27	.	.	.
cord-293701-u4ntxo0y	214	1	Another	another	DT
cord-293701-u4ntxo0y	214	2	study	study	NN
cord-293701-u4ntxo0y	214	3	found	find	VBD
cord-293701-u4ntxo0y	214	4	that	that	IN
cord-293701-u4ntxo0y	214	5	SARS	SARS	NNP
cord-293701-u4ntxo0y	214	6	-	-	HYPH
cord-293701-u4ntxo0y	214	7	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	214	8	S	S	NNP
cord-293701-u4ntxo0y	214	9	protein	protein	NN
cord-293701-u4ntxo0y	214	10	-	-	HYPH
cord-293701-u4ntxo0y	214	11	specific	specific	JJ
cord-293701-u4ntxo0y	214	12	memory	memory	NN
cord-293701-u4ntxo0y	214	13	B	b	NN
cord-293701-u4ntxo0y	214	14	cells	cell	NNS
cord-293701-u4ntxo0y	214	15	and	and	CC
cord-293701-u4ntxo0y	214	16	circulating	circulate	VBG
cord-293701-u4ntxo0y	214	17	follicular	follicular	JJ
cord-293701-u4ntxo0y	214	18	helper	helper	NN
cord-293701-u4ntxo0y	214	19	T	t	NN
cord-293701-u4ntxo0y	214	20	cells	cell	NNS
cord-293701-u4ntxo0y	214	21	are	be	VBP
cord-293701-u4ntxo0y	214	22	positively	positively	RB
cord-293701-u4ntxo0y	214	23	associated	associate	VBN
cord-293701-u4ntxo0y	214	24	with	with	IN
cord-293701-u4ntxo0y	214	25	plasma	plasma	NN
cord-293701-u4ntxo0y	214	26	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	214	27	activity	activity	NN
cord-293701-u4ntxo0y	214	28	118	118	CD
cord-293701-u4ntxo0y	214	29	.	.	.
cord-293701-u4ntxo0y	215	1	Therefore	therefore	RB
cord-293701-u4ntxo0y	215	2	,	,	,
cord-293701-u4ntxo0y	215	3	these	these	DT
cord-293701-u4ntxo0y	215	4	two	two	CD
cord-293701-u4ntxo0y	215	5	indicators	indicator	NNS
cord-293701-u4ntxo0y	215	6	may	may	MD
cord-293701-u4ntxo0y	215	7	be	be	VB
cord-293701-u4ntxo0y	215	8	useful	useful	JJ
cord-293701-u4ntxo0y	215	9	for	for	IN
cord-293701-u4ntxo0y	215	10	the	the	DT
cord-293701-u4ntxo0y	215	11	surveillance	surveillance	NN
cord-293701-u4ntxo0y	215	12	of	of	IN
cord-293701-u4ntxo0y	215	13	the	the	DT
cord-293701-u4ntxo0y	215	14	longevity	longevity	NN
cord-293701-u4ntxo0y	215	15	of	of	IN
cord-293701-u4ntxo0y	215	16	immune	immune	JJ
cord-293701-u4ntxo0y	215	17	responses	response	NNS
cord-293701-u4ntxo0y	215	18	to	to	IN
cord-293701-u4ntxo0y	215	19	SARS	SARS	NNP
cord-293701-u4ntxo0y	215	20	-	-	HYPH
cord-293701-u4ntxo0y	215	21	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	215	22	after	after	IN
cord-293701-u4ntxo0y	215	23	vaccination	vaccination	NN
cord-293701-u4ntxo0y	215	24	.	.	.
cord-293701-u4ntxo0y	216	1	Our	-PRON-	PRP$
cord-293701-u4ntxo0y	216	2	previous	previous	JJ
cord-293701-u4ntxo0y	216	3	study	study	NN
cord-293701-u4ntxo0y	216	4	showed	show	VBD
cord-293701-u4ntxo0y	216	5	that	that	IN
cord-293701-u4ntxo0y	216	6	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	216	7	in	in	IN
cord-293701-u4ntxo0y	216	8	the	the	DT
cord-293701-u4ntxo0y	216	9	sera	sera	NNP
cord-293701-u4ntxo0y	216	10	of	of	IN
cord-293701-u4ntxo0y	216	11	mice	mouse	NNS
cord-293701-u4ntxo0y	216	12	immunized	immunize	VBN
cord-293701-u4ntxo0y	216	13	with	with	IN
cord-293701-u4ntxo0y	216	14	an	an	DT
cord-293701-u4ntxo0y	216	15	RBDbased	rbdbase	VBN
cord-293701-u4ntxo0y	216	16	SARS	SARS	NNP
cord-293701-u4ntxo0y	216	17	vaccine	vaccine	NN
cord-293701-u4ntxo0y	216	18	can	can	MD
cord-293701-u4ntxo0y	216	19	be	be	VB
cord-293701-u4ntxo0y	216	20	maintained	maintain	VBN
cord-293701-u4ntxo0y	216	21	at	at	IN
cord-293701-u4ntxo0y	216	22	a	a	DT
cord-293701-u4ntxo0y	216	23	high	high	JJ
cord-293701-u4ntxo0y	216	24	titre	titre	NN
cord-293701-u4ntxo0y	216	25	(	(	-LRB-
cord-293701-u4ntxo0y	216	26	1:580	1:580	CD
cord-293701-u4ntxo0y	216	27	)	)	-RRB-
cord-293701-u4ntxo0y	216	28	for	for	IN
cord-293701-u4ntxo0y	216	29	6	6	CD
cord-293701-u4ntxo0y	216	30	months	month	NNS
cord-293701-u4ntxo0y	216	31	113	113	CD
cord-293701-u4ntxo0y	216	32	.	.	.
cord-293701-u4ntxo0y	217	1	Therefore	therefore	RB
cord-293701-u4ntxo0y	217	2	,	,	,
cord-293701-u4ntxo0y	217	3	we	-PRON-	PRP
cord-293701-u4ntxo0y	217	4	propose	propose	VBP
cord-293701-u4ntxo0y	217	5	that	that	IN
cord-293701-u4ntxo0y	217	6	NAb	nab	JJ
cord-293701-u4ntxo0y	217	7	responses	response	NNS
cord-293701-u4ntxo0y	217	8	elicited	elicit	VBN
cord-293701-u4ntxo0y	217	9	by	by	IN
cord-293701-u4ntxo0y	217	10	a	a	DT
cord-293701-u4ntxo0y	217	11	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	217	12	vaccine	vaccine	NN
cord-293701-u4ntxo0y	217	13	should	should	MD
cord-293701-u4ntxo0y	217	14	last	last	VB
cord-293701-u4ntxo0y	217	15	for	for	IN
cord-293701-u4ntxo0y	217	16	at	at	RB
cord-293701-u4ntxo0y	217	17	least	least	RBS
cord-293701-u4ntxo0y	217	18	6	6	CD
cord-293701-u4ntxo0y	217	19	months	month	NNS
cord-293701-u4ntxo0y	217	20	in	in	IN
cord-293701-u4ntxo0y	217	21	vaccinated	vaccinated	JJ
cord-293701-u4ntxo0y	217	22	mice	mouse	NNS
cord-293701-u4ntxo0y	217	23	.	.	.
cord-293701-u4ntxo0y	218	1	An	an	DT
cord-293701-u4ntxo0y	218	2	ideal	ideal	JJ
cord-293701-u4ntxo0y	218	3	antigen	antigen	NN
cord-293701-u4ntxo0y	218	4	should	should	MD
cord-293701-u4ntxo0y	218	5	be	be	VB
cord-293701-u4ntxo0y	218	6	selected	select	VBN
cord-293701-u4ntxo0y	218	7	for	for	IN
cord-293701-u4ntxo0y	218	8	the	the	DT
cord-293701-u4ntxo0y	218	9	development	development	NN
cord-293701-u4ntxo0y	218	10	of	of	IN
cord-293701-u4ntxo0y	218	11	a	a	DT
cord-293701-u4ntxo0y	218	12	safe	safe	JJ
cord-293701-u4ntxo0y	218	13	and	and	CC
cord-293701-u4ntxo0y	218	14	effective	effective	JJ
cord-293701-u4ntxo0y	218	15	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	218	16	vaccine	vaccine	NN
cord-293701-u4ntxo0y	218	17	.	.	.
cord-293701-u4ntxo0y	219	1	The	the	DT
cord-293701-u4ntxo0y	219	2	S	S	NNP
cord-293701-u4ntxo0y	219	3	protein	protein	NN
cord-293701-u4ntxo0y	219	4	is	be	VBZ
cord-293701-u4ntxo0y	219	5	the	the	DT
cord-293701-u4ntxo0y	219	6	major	major	JJ
cord-293701-u4ntxo0y	219	7	antigen	antigen	NN
cord-293701-u4ntxo0y	219	8	in	in	IN
cord-293701-u4ntxo0y	219	9	most	most	JJS
cord-293701-u4ntxo0y	219	10	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	219	11	vaccine	vaccine	NN
cord-293701-u4ntxo0y	219	12	candidates	candidate	NNS
cord-293701-u4ntxo0y	219	13	under	under	IN
cord-293701-u4ntxo0y	219	14	development	development	NN
cord-293701-u4ntxo0y	219	15	as	as	IN
cord-293701-u4ntxo0y	219	16	it	-PRON-	PRP
cord-293701-u4ntxo0y	219	17	contains	contain	VBZ
cord-293701-u4ntxo0y	219	18	the	the	DT
cord-293701-u4ntxo0y	219	19	major	major	JJ
cord-293701-u4ntxo0y	219	20	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	219	21	epitopes	epitope	NNS
cord-293701-u4ntxo0y	219	22	and	and	CC
cord-293701-u4ntxo0y	219	23	is	be	VBZ
cord-293701-u4ntxo0y	219	24	located	locate	VBN
cord-293701-u4ntxo0y	219	25	on	on	IN
cord-293701-u4ntxo0y	219	26	the	the	DT
cord-293701-u4ntxo0y	219	27	surface	surface	NN
cord-293701-u4ntxo0y	219	28	of	of	IN
cord-293701-u4ntxo0y	219	29	the	the	DT
cord-293701-u4ntxo0y	219	30	viral	viral	JJ
cord-293701-u4ntxo0y	219	31	particle	particle	NN
cord-293701-u4ntxo0y	219	32	.	.	.
cord-293701-u4ntxo0y	220	1	However	however	RB
cord-293701-u4ntxo0y	220	2	,	,	,
cord-293701-u4ntxo0y	220	3	the	the	DT
cord-293701-u4ntxo0y	220	4	full	full	JJ
cord-293701-u4ntxo0y	220	5	-	-	HYPH
cord-293701-u4ntxo0y	220	6	length	length	NN
cord-293701-u4ntxo0y	220	7	S	s	NN
cord-293701-u4ntxo0y	220	8	protein	protein	NN
cord-293701-u4ntxo0y	220	9	of	of	IN
cord-293701-u4ntxo0y	220	10	SARS	SARS	NNP
cord-293701-u4ntxo0y	220	11	-	-	HYPH
cord-293701-u4ntxo0y	220	12	CoV	CoV	NNP
cord-293701-u4ntxo0y	220	13	also	also	RB
cord-293701-u4ntxo0y	220	14	contains	contain	VBZ
cord-293701-u4ntxo0y	220	15	several	several	JJ
cord-293701-u4ntxo0y	220	16	immunodominant	immunodominant	JJ
cord-293701-u4ntxo0y	220	17	sites	site	NNS
cord-293701-u4ntxo0y	220	18	that	that	WDT
cord-293701-u4ntxo0y	220	19	can	can	MD
cord-293701-u4ntxo0y	220	20	induce	induce	VB
cord-293701-u4ntxo0y	220	21	non	non	JJ
cord-293701-u4ntxo0y	220	22	-	-	JJ
cord-293701-u4ntxo0y	220	23	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	220	24	antibodies	antibody	NNS
cord-293701-u4ntxo0y	220	25	,	,	,
cord-293701-u4ntxo0y	220	26	including	include	VBG
cord-293701-u4ntxo0y	220	27	those	those	DT
cord-293701-u4ntxo0y	220	28	associated	associate	VBN
cord-293701-u4ntxo0y	220	29	with	with	IN
cord-293701-u4ntxo0y	220	30	ADE	ADE	NNP
cord-293701-u4ntxo0y	220	31	,	,	,
cord-293701-u4ntxo0y	220	32	or	or	CC
cord-293701-u4ntxo0y	220	33	harmful	harmful	JJ
cord-293701-u4ntxo0y	220	34	immune	immune	JJ
cord-293701-u4ntxo0y	220	35	responses	response	NNS
cord-293701-u4ntxo0y	220	36	78	78	CD
cord-293701-u4ntxo0y	220	37	,	,	,
cord-293701-u4ntxo0y	220	38	79	79	CD
cord-293701-u4ntxo0y	220	39	,	,	,
cord-293701-u4ntxo0y	220	40	83	83	CD
cord-293701-u4ntxo0y	220	41	,	,	,
cord-293701-u4ntxo0y	220	42	84	84	CD
cord-293701-u4ntxo0y	220	43	,	,	,
cord-293701-u4ntxo0y	220	44	119	119	CD
cord-293701-u4ntxo0y	220	45	,	,	,
cord-293701-u4ntxo0y	220	46	120	120	CD
cord-293701-u4ntxo0y	220	47	.	.	.
cord-293701-u4ntxo0y	221	1	For	for	IN
cord-293701-u4ntxo0y	221	2	example	example	NN
cord-293701-u4ntxo0y	221	3	,	,	,
cord-293701-u4ntxo0y	221	4	antibodies	antibody	NNS
cord-293701-u4ntxo0y	221	5	targeting	target	VBG
cord-293701-u4ntxo0y	221	6	the	the	DT
cord-293701-u4ntxo0y	221	7	S597	S597	NNPS
cord-293701-u4ntxo0y	221	8	-	-	:
cord-293701-u4ntxo0y	221	9	603	603	CD
cord-293701-u4ntxo0y	221	10	epitope	epitope	NN
cord-293701-u4ntxo0y	221	11	,	,	,
cord-293701-u4ntxo0y	221	12	which	which	WDT
cord-293701-u4ntxo0y	221	13	is	be	VBZ
cord-293701-u4ntxo0y	221	14	located	locate	VBN
cord-293701-u4ntxo0y	221	15	close	close	RB
cord-293701-u4ntxo0y	221	16	to	to	IN
cord-293701-u4ntxo0y	221	17	the	the	DT
cord-293701-u4ntxo0y	221	18	carboxy	carboxy	JJ
cord-293701-u4ntxo0y	221	19	terminus	terminus	NN
cord-293701-u4ntxo0y	221	20	of	of	IN
cord-293701-u4ntxo0y	221	21	the	the	DT
cord-293701-u4ntxo0y	221	22	RBD	RBD	NNP
cord-293701-u4ntxo0y	221	23	of	of	IN
cord-293701-u4ntxo0y	221	24	SARS	SARS	NNP
cord-293701-u4ntxo0y	221	25	-	-	HYPH
cord-293701-u4ntxo0y	221	26	CoV	CoV	NNP
cord-293701-u4ntxo0y	221	27	S	S	NNP
cord-293701-u4ntxo0y	221	28	protein	protein	NN
cord-293701-u4ntxo0y	221	29	,	,	,
cord-293701-u4ntxo0y	221	30	markedly	markedly	RB
cord-293701-u4ntxo0y	221	31	enhanced	enhance	VBN
cord-293701-u4ntxo0y	221	32	SARS	SARS	NNP
cord-293701-u4ntxo0y	221	33	-	-	HYPH
cord-293701-u4ntxo0y	221	34	CoV	cov	NN
cord-293701-u4ntxo0y	221	35	infection	infection	NN
cord-293701-u4ntxo0y	221	36	of	of	IN
cord-293701-u4ntxo0y	221	37	Vero	Vero	NNP
cord-293701-u4ntxo0y	221	38	E6	E6	NNP
cord-293701-u4ntxo0y	221	39	cells	cell	NNS
cord-293701-u4ntxo0y	221	40	compared	compare	VBN
cord-293701-u4ntxo0y	221	41	with	with	IN
cord-293701-u4ntxo0y	221	42	antibodies	antibody	NNS
cord-293701-u4ntxo0y	221	43	from	from	IN
cord-293701-u4ntxo0y	221	44	unimmunized	unimmunized	JJ
cord-293701-u4ntxo0y	221	45	macaques	macaque	NNS
cord-293701-u4ntxo0y	221	46	79	79	CD
cord-293701-u4ntxo0y	221	47	.	.	.
cord-293701-u4ntxo0y	222	1	The	the	DT
cord-293701-u4ntxo0y	222	2	RBD	RBD	NNP
cord-293701-u4ntxo0y	222	3	subunit	subunit	NN
cord-293701-u4ntxo0y	222	4	of	of	IN
cord-293701-u4ntxo0y	222	5	SARS	SARS	NNP
cord-293701-u4ntxo0y	222	6	-	-	HYPH
cord-293701-u4ntxo0y	222	7	CoV	CoV	NNP
cord-293701-u4ntxo0y	222	8	S	S	NNP
cord-293701-u4ntxo0y	222	9	protein	protein	NN
cord-293701-u4ntxo0y	222	10	elicited	elicit	VBD
cord-293701-u4ntxo0y	222	11	a	a	DT
cord-293701-u4ntxo0y	222	12	strong	strong	JJ
cord-293701-u4ntxo0y	222	13	NAb	NAb	NNS
cord-293701-u4ntxo0y	222	14	response	response	NN
cord-293701-u4ntxo0y	222	15	and	and	CC
cord-293701-u4ntxo0y	222	16	protected	protect	VBN
cord-293701-u4ntxo0y	222	17	against	against	IN
cord-293701-u4ntxo0y	222	18	SARS	SARS	NNP
cord-293701-u4ntxo0y	222	19	-	-	HYPH
cord-293701-u4ntxo0y	222	20	CoV	CoV	NNP
cord-293701-u4ntxo0y	222	21	challenge	challenge	NN
cord-293701-u4ntxo0y	222	22	,	,	,
cord-293701-u4ntxo0y	222	23	without	without	IN
cord-293701-u4ntxo0y	222	24	obvious	obvious	JJ
cord-293701-u4ntxo0y	222	25	VADE	vade	NN
cord-293701-u4ntxo0y	222	26	,	,	,
cord-293701-u4ntxo0y	222	27	in	in	IN
cord-293701-u4ntxo0y	222	28	a	a	DT
cord-293701-u4ntxo0y	222	29	mouse	mouse	NN
cord-293701-u4ntxo0y	222	30	model	model	NN
cord-293701-u4ntxo0y	222	31	121	121	CD
cord-293701-u4ntxo0y	222	32	,	,	,
cord-293701-u4ntxo0y	222	33	122	122	CD
cord-293701-u4ntxo0y	222	34	.	.	.
cord-293701-u4ntxo0y	223	1	Our	-PRON-	PRP$
cord-293701-u4ntxo0y	223	2	previous	previous	JJ
cord-293701-u4ntxo0y	223	3	studies	study	NNS
cord-293701-u4ntxo0y	223	4	demonstrated	demonstrate	VBD
cord-293701-u4ntxo0y	223	5	that	that	IN
cord-293701-u4ntxo0y	223	6	the	the	DT
cord-293701-u4ntxo0y	223	7	RBD	RBD	NNP
cord-293701-u4ntxo0y	223	8	contains	contain	VBZ
cord-293701-u4ntxo0y	223	9	the	the	DT
cord-293701-u4ntxo0y	223	10	main	main	JJ
cord-293701-u4ntxo0y	223	11	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	223	12	epitopes	epitope	NNS
cord-293701-u4ntxo0y	223	13	in	in	IN
cord-293701-u4ntxo0y	223	14	the	the	DT
cord-293701-u4ntxo0y	223	15	S	S	NNP
cord-293701-u4ntxo0y	223	16	protein	protein	NN
cord-293701-u4ntxo0y	223	17	able	able	JJ
cord-293701-u4ntxo0y	223	18	to	to	TO
cord-293701-u4ntxo0y	223	19	induce	induce	VB
cord-293701-u4ntxo0y	223	20	higher	high	JJR
cord-293701-u4ntxo0y	223	21	titres	titre	NNS
cord-293701-u4ntxo0y	223	22	of	of	IN
cord-293701-u4ntxo0y	223	23	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	223	24	,	,	,
cord-293701-u4ntxo0y	223	25	but	but	CC
cord-293701-u4ntxo0y	223	26	lower	low	JJR
cord-293701-u4ntxo0y	223	27	levels	level	NNS
cord-293701-u4ntxo0y	223	28	of	of	IN
cord-293701-u4ntxo0y	223	29	non	non	JJ
cord-293701-u4ntxo0y	223	30	-	-	JJ
cord-293701-u4ntxo0y	223	31	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	223	32	antibodies	antibody	NNS
cord-293701-u4ntxo0y	223	33	,	,	,
cord-293701-u4ntxo0y	223	34	compared	compare	VBN
cord-293701-u4ntxo0y	223	35	with	with	IN
cord-293701-u4ntxo0y	223	36	the	the	DT
cord-293701-u4ntxo0y	223	37	S1	s1	NN
cord-293701-u4ntxo0y	223	38	subunit	subunit	NN
cord-293701-u4ntxo0y	223	39	or	or	CC
cord-293701-u4ntxo0y	223	40	full	full	JJ
cord-293701-u4ntxo0y	223	41	-	-	HYPH
cord-293701-u4ntxo0y	223	42	length	length	NN
cord-293701-u4ntxo0y	223	43	S	s	NN
cord-293701-u4ntxo0y	223	44	protein	protein	NN
cord-293701-u4ntxo0y	223	45	[	[	-LRB-
cord-293701-u4ntxo0y	223	46	123	123	CD
cord-293701-u4ntxo0y	223	47	]	]	-RRB-
cord-293701-u4ntxo0y	223	48	[	[	-LRB-
cord-293701-u4ntxo0y	223	49	124	124	CD
cord-293701-u4ntxo0y	223	50	]	]	-RRB-
cord-293701-u4ntxo0y	223	51	[	[	-LRB-
cord-293701-u4ntxo0y	223	52	125	125	CD
cord-293701-u4ntxo0y	223	53	]	]	-RRB-
cord-293701-u4ntxo0y	223	54	[	[	-LRB-
cord-293701-u4ntxo0y	223	55	126	126	CD
cord-293701-u4ntxo0y	223	56	]	]	-RRB-
cord-293701-u4ntxo0y	223	57	[	[	-LRB-
cord-293701-u4ntxo0y	223	58	127	127	CD
cord-293701-u4ntxo0y	223	59	]	]	-RRB-
cord-293701-u4ntxo0y	223	60	.	.	.
cord-293701-u4ntxo0y	224	1	SARS	SARS	NNP
cord-293701-u4ntxo0y	224	2	-	-	HYPH
cord-293701-u4ntxo0y	224	3	CoV	cov	NN
cord-293701-u4ntxo0y	224	4	RBD	RBD	NNP
cord-293701-u4ntxo0y	224	5	with	with	IN
cord-293701-u4ntxo0y	224	6	Alhydrogel	Alhydrogel	NNP
cord-293701-u4ntxo0y	224	7	(	(	-LRB-
cord-293701-u4ntxo0y	224	8	1:25	1:25	CD
cord-293701-u4ntxo0y	224	9	)	)	-RRB-
cord-293701-u4ntxo0y	224	10	as	as	IN
cord-293701-u4ntxo0y	224	11	an	an	DT
cord-293701-u4ntxo0y	224	12	adjuvant	adjuvant	NN
cord-293701-u4ntxo0y	224	13	induced	induce	VBN
cord-293701-u4ntxo0y	224	14	strong	strong	JJ
cord-293701-u4ntxo0y	224	15	protection	protection	NN
cord-293701-u4ntxo0y	224	16	without	without	IN
cord-293701-u4ntxo0y	224	17	signs	sign	NNS
cord-293701-u4ntxo0y	224	18	of	of	IN
cord-293701-u4ntxo0y	224	19	VADE	VADE	NNP
cord-293701-u4ntxo0y	224	20	,	,	,
cord-293701-u4ntxo0y	224	21	whereas	whereas	IN
cord-293701-u4ntxo0y	224	22	full	full	JJ
cord-293701-u4ntxo0y	224	23	-	-	HYPH
cord-293701-u4ntxo0y	224	24	length	length	NN
cord-293701-u4ntxo0y	224	25	SARS	SARS	NNP
cord-293701-u4ntxo0y	224	26	-	-	HYPH
cord-293701-u4ntxo0y	224	27	CoV	CoV	NNP
cord-293701-u4ntxo0y	224	28	S	S	NNP
cord-293701-u4ntxo0y	224	29	protein	protein	NN
cord-293701-u4ntxo0y	224	30	induced	induce	VBD
cord-293701-u4ntxo0y	224	31	weak	weak	JJ
cord-293701-u4ntxo0y	224	32	protection	protection	NN
cord-293701-u4ntxo0y	224	33	and	and	CC
cord-293701-u4ntxo0y	224	34	strong	strong	JJ
cord-293701-u4ntxo0y	224	35	VADE	vade	NN
cord-293701-u4ntxo0y	224	36	in	in	IN
cord-293701-u4ntxo0y	224	37	a	a	DT
cord-293701-u4ntxo0y	224	38	mouse	mouse	NN
cord-293701-u4ntxo0y	224	39	model	model	NN
cord-293701-u4ntxo0y	224	40	115	115	CD
cord-293701-u4ntxo0y	224	41	.	.	.
cord-293701-u4ntxo0y	225	1	Meanwhile	meanwhile	RB
cord-293701-u4ntxo0y	225	2	,	,	,
cord-293701-u4ntxo0y	225	3	most	most	JJS
cord-293701-u4ntxo0y	225	4	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	225	5	isolated	isolate	VBN
cord-293701-u4ntxo0y	225	6	from	from	IN
cord-293701-u4ntxo0y	225	7	the	the	DT
cord-293701-u4ntxo0y	225	8	serum	serum	NN
cord-293701-u4ntxo0y	225	9	of	of	IN
cord-293701-u4ntxo0y	225	10	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	225	11	-	-	HYPH
cord-293701-u4ntxo0y	225	12	infected	infect	VBN
cord-293701-u4ntxo0y	225	13	patients	patient	NNS
cord-293701-u4ntxo0y	225	14	target	target	VBP
cord-293701-u4ntxo0y	225	15	the	the	DT
cord-293701-u4ntxo0y	225	16	RBD	RBD	NNP
cord-293701-u4ntxo0y	225	17	128	128	CD
cord-293701-u4ntxo0y	225	18	,	,	,
cord-293701-u4ntxo0y	225	19	129	129	CD
cord-293701-u4ntxo0y	225	20	.	.	.
cord-293701-u4ntxo0y	226	1	Furthermore	furthermore	RB
cord-293701-u4ntxo0y	226	2	,	,	,
cord-293701-u4ntxo0y	226	3	the	the	DT
cord-293701-u4ntxo0y	226	4	SARS	SARS	NNP
cord-293701-u4ntxo0y	226	5	-	-	HYPH
cord-293701-u4ntxo0y	226	6	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	226	7	RBD	RBD	NNP
cord-293701-u4ntxo0y	226	8	elicited	elicit	VBD
cord-293701-u4ntxo0y	226	9	a	a	DT
cord-293701-u4ntxo0y	226	10	potent	potent	JJ
cord-293701-u4ntxo0y	226	11	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	226	12	response	response	NN
cord-293701-u4ntxo0y	226	13	without	without	IN
cord-293701-u4ntxo0y	226	14	ADE	ADE	NNP
cord-293701-u4ntxo0y	226	15	in	in	IN
cord-293701-u4ntxo0y	226	16	mice	mice	NN
cord-293701-u4ntxo0y	226	17	130	130	CD
cord-293701-u4ntxo0y	226	18	.	.	.
cord-293701-u4ntxo0y	227	1	RBDdimer	RBDdimer	NNP
cord-293701-u4ntxo0y	227	2	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	227	3	against	against	IN
cord-293701-u4ntxo0y	227	4	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	227	5	,	,	,
cord-293701-u4ntxo0y	227	6	SARS	SARS	NNP
cord-293701-u4ntxo0y	227	7	or	or	CC
cord-293701-u4ntxo0y	227	8	MERS	MERS	NNP
cord-293701-u4ntxo0y	227	9	induced	induce	VBD
cord-293701-u4ntxo0y	227	10	NAb	nab	VBP
cord-293701-u4ntxo0y	227	11	responses	response	NNS
cord-293701-u4ntxo0y	227	12	to	to	IN
cord-293701-u4ntxo0y	227	13	the	the	DT
cord-293701-u4ntxo0y	227	14	corresponding	corresponding	JJ
cord-293701-u4ntxo0y	227	15	virus	virus	NN
cord-293701-u4ntxo0y	227	16	and	and	CC
cord-293701-u4ntxo0y	227	17	showed	show	VBD
cord-293701-u4ntxo0y	227	18	high	high	JJ
cord-293701-u4ntxo0y	227	19	yields	yield	NNS
cord-293701-u4ntxo0y	227	20	in	in	IN
cord-293701-u4ntxo0y	227	21	pilot	pilot	NN
cord-293701-u4ntxo0y	227	22	-	-	HYPH
cord-293701-u4ntxo0y	227	23	scale	scale	NN
cord-293701-u4ntxo0y	227	24	production	production	NN
cord-293701-u4ntxo0y	227	25	131	131	CD
cord-293701-u4ntxo0y	227	26	.	.	.
cord-293701-u4ntxo0y	228	1	Our	-PRON-	PRP$
cord-293701-u4ntxo0y	228	2	recent	recent	JJ
cord-293701-u4ntxo0y	228	3	study	study	NN
cord-293701-u4ntxo0y	228	4	demonstrated	demonstrate	VBD
cord-293701-u4ntxo0y	228	5	that	that	IN
cord-293701-u4ntxo0y	228	6	a	a	DT
cord-293701-u4ntxo0y	228	7	lipid	lipid	NN
cord-293701-u4ntxo0y	228	8	nanoparticleencapsulated	nanoparticleencapsulate	VBN
cord-293701-u4ntxo0y	228	9	RBD	RBD	NNP
cord-293701-u4ntxo0y	228	10	-	-	HYPH
cord-293701-u4ntxo0y	228	11	based	base	VBN
cord-293701-u4ntxo0y	228	12	mRNA	mRNA	NNP
cord-293701-u4ntxo0y	228	13	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	228	14	vaccine	vaccine	NN
cord-293701-u4ntxo0y	228	15	elicited	elicit	VBD
cord-293701-u4ntxo0y	228	16	robust	robust	JJ
cord-293701-u4ntxo0y	228	17	T	T	NNP
cord-293701-u4ntxo0y	228	18	cell	cell	NN
cord-293701-u4ntxo0y	228	19	responses	response	NNS
cord-293701-u4ntxo0y	228	20	and	and	CC
cord-293701-u4ntxo0y	228	21	highly	highly	RB
cord-293701-u4ntxo0y	228	22	potent	potent	JJ
cord-293701-u4ntxo0y	228	23	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	228	24	against	against	IN
cord-293701-u4ntxo0y	228	25	live	live	JJ
cord-293701-u4ntxo0y	228	26	SARS	SARS	NNP
cord-293701-u4ntxo0y	228	27	-	-	HYPH
cord-293701-u4ntxo0y	228	28	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	228	29	infection	infection	NN
cord-293701-u4ntxo0y	228	30	with	with	IN
cord-293701-u4ntxo0y	228	31	an	an	DT
cord-293701-u4ntxo0y	228	32	NAb	NAb	NNP
cord-293701-u4ntxo0y	228	33	titre	titre	NN
cord-293701-u4ntxo0y	228	34	of	of	IN
cord-293701-u4ntxo0y	228	35	1:540	1:540	CD
cord-293701-u4ntxo0y	228	36	at	at	IN
cord-293701-u4ntxo0y	228	37	70	70	CD
cord-293701-u4ntxo0y	228	38	days	day	NNS
cord-293701-u4ntxo0y	228	39	after	after	IN
cord-293701-u4ntxo0y	228	40	boost	boost	NN
cord-293701-u4ntxo0y	228	41	immunization	immunization	NN
cord-293701-u4ntxo0y	228	42	in	in	IN
cord-293701-u4ntxo0y	228	43	mice	mouse	NNS
cord-293701-u4ntxo0y	228	44	132	132	CD
cord-293701-u4ntxo0y	228	45	.	.	.
cord-293701-u4ntxo0y	229	1	These	these	DT
cord-293701-u4ntxo0y	229	2	antibodies	antibody	NNS
cord-293701-u4ntxo0y	229	3	could	could	MD
cord-293701-u4ntxo0y	229	4	also	also	RB
cord-293701-u4ntxo0y	229	5	cross	cross	VB
cord-293701-u4ntxo0y	229	6	-	-	JJ
cord-293701-u4ntxo0y	229	7	neutralize	neutralize	VB
cord-293701-u4ntxo0y	229	8	SARS	SARS	NNP
cord-293701-u4ntxo0y	229	9	-	-	HYPH
cord-293701-u4ntxo0y	229	10	CoV	CoV	NNP
cord-293701-u4ntxo0y	229	11	pseudoviruses	pseudoviruse	NNS
cord-293701-u4ntxo0y	229	12	expressing	express	VBG
cord-293701-u4ntxo0y	229	13	A	a	DT
cord-293701-u4ntxo0y	229	14	proteins	protein	NNS
cord-293701-u4ntxo0y	229	15	of	of	IN
cord-293701-u4ntxo0y	229	16	human	human	JJ
cord-293701-u4ntxo0y	229	17	SARS	SARS	NNP
cord-293701-u4ntxo0y	229	18	-	-	HYPH
cord-293701-u4ntxo0y	229	19	CoV	CoV	NNP
cord-293701-u4ntxo0y	229	20	strains	strain	VBZ
cord-293701-u4ntxo0y	229	21	Tor2	Tor2	NNP
cord-293701-u4ntxo0y	229	22	and	and	CC
cord-293701-u4ntxo0y	229	23	GD03	GD03	NNP
cord-293701-u4ntxo0y	229	24	,	,	,
cord-293701-u4ntxo0y	229	25	as	as	RB
cord-293701-u4ntxo0y	229	26	well	well	RB
cord-293701-u4ntxo0y	229	27	as	as	IN
cord-293701-u4ntxo0y	230	1	palm	palm	NNP
cord-293701-u4ntxo0y	230	2	civet	civet	NNP
cord-293701-u4ntxo0y	230	3	strain	strain	VBP
cord-293701-u4ntxo0y	230	4	SZ3	SZ3	NNP
cord-293701-u4ntxo0y	230	5	,	,	,
cord-293701-u4ntxo0y	230	6	suggesting	suggest	VBG
cord-293701-u4ntxo0y	230	7	that	that	IN
cord-293701-u4ntxo0y	230	8	this	this	DT
cord-293701-u4ntxo0y	230	9	RBD	RBD	NNP
cord-293701-u4ntxo0y	230	10	-	-	HYPH
cord-293701-u4ntxo0y	230	11	based	base	VBN
cord-293701-u4ntxo0y	230	12	mRNA	mRNA	NNP
cord-293701-u4ntxo0y	230	13	vaccine	vaccine	NN
cord-293701-u4ntxo0y	230	14	has	have	VBZ
cord-293701-u4ntxo0y	230	15	potential	potential	JJ
cord-293701-u4ntxo0y	230	16	to	to	TO
cord-293701-u4ntxo0y	230	17	be	be	VB
cord-293701-u4ntxo0y	230	18	further	further	RB
cord-293701-u4ntxo0y	230	19	developed	develop	VBN
cord-293701-u4ntxo0y	230	20	as	as	IN
cord-293701-u4ntxo0y	230	21	a	a	DT
cord-293701-u4ntxo0y	230	22	safe	safe	JJ
cord-293701-u4ntxo0y	230	23	and	and	CC
cord-293701-u4ntxo0y	230	24	effective	effective	JJ
cord-293701-u4ntxo0y	230	25	vaccine	vaccine	NN
cord-293701-u4ntxo0y	230	26	to	to	TO
cord-293701-u4ntxo0y	230	27	prevent	prevent	VB
cord-293701-u4ntxo0y	230	28	both	both	DT
cord-293701-u4ntxo0y	230	29	SARS	SARS	NNP
cord-293701-u4ntxo0y	230	30	-	-	HYPH
cord-293701-u4ntxo0y	230	31	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	230	32	and	and	CC
cord-293701-u4ntxo0y	230	33	SARS	SARS	NNP
cord-293701-u4ntxo0y	230	34	-	-	HYPH
cord-293701-u4ntxo0y	230	35	CoV	CoV	NNP
cord-293701-u4ntxo0y	230	36	infection	infection	NN
cord-293701-u4ntxo0y	230	37	.	.	.
cord-293701-u4ntxo0y	231	1	Another	another	DT
cord-293701-u4ntxo0y	231	2	lipid	lipid	NN
cord-293701-u4ntxo0y	231	3	nanoparticle	nanoparticle	NN
cord-293701-u4ntxo0y	231	4	-	-	HYPH
cord-293701-u4ntxo0y	231	5	encapsulated	encapsulate	VBN
cord-293701-u4ntxo0y	231	6	SARS	SARS	NNP
cord-293701-u4ntxo0y	231	7	-	-	HYPH
cord-293701-u4ntxo0y	231	8	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	231	9	RBD	RBD	NNP
cord-293701-u4ntxo0y	231	10	-	-	HYPH
cord-293701-u4ntxo0y	231	11	based	base	VBN
cord-293701-u4ntxo0y	231	12	mRNA	mRNA	NNP
cord-293701-u4ntxo0y	231	13	vaccine	vaccine	NN
cord-293701-u4ntxo0y	231	14	(	(	-LRB-
cord-293701-u4ntxo0y	231	15	ARCoV	ARCoV	NNP
cord-293701-u4ntxo0y	231	16	)	)	-RRB-
cord-293701-u4ntxo0y	231	17	elicited	elicit	VBD
cord-293701-u4ntxo0y	231	18	robust	robust	JJ
cord-293701-u4ntxo0y	231	19	NAbs	NAbs	NNP
cord-293701-u4ntxo0y	231	20	and	and	CC
cord-293701-u4ntxo0y	231	21	T	T	NNP
cord-293701-u4ntxo0y	231	22	H	h	NN
cord-293701-u4ntxo0y	231	23	1	1	CD
cord-293701-u4ntxo0y	231	24	cellbiased	cellbiase	VBN
cord-293701-u4ntxo0y	231	25	cellular	cellular	JJ
cord-293701-u4ntxo0y	231	26	response	response	NN
cord-293701-u4ntxo0y	231	27	in	in	IN
cord-293701-u4ntxo0y	231	28	mice	mouse	NNS
cord-293701-u4ntxo0y	231	29	and	and	CC
cord-293701-u4ntxo0y	231	30	nonhuman	nonhuman	NN
cord-293701-u4ntxo0y	231	31	primates	primate	NNS
cord-293701-u4ntxo0y	231	32	,	,	,
cord-293701-u4ntxo0y	231	33	while	while	IN
cord-293701-u4ntxo0y	231	34	conferring	confer	VBG
cord-293701-u4ntxo0y	231	35	complete	complete	JJ
cord-293701-u4ntxo0y	231	36	protection	protection	NN
cord-293701-u4ntxo0y	231	37	against	against	IN
cord-293701-u4ntxo0y	231	38	mouse	mouse	NN
cord-293701-u4ntxo0y	231	39	-	-	HYPH
cord-293701-u4ntxo0y	231	40	adapted	adapt	VBN
cord-293701-u4ntxo0y	231	41	SARS	SARS	NNP
cord-293701-u4ntxo0y	231	42	-	-	HYPH
cord-293701-u4ntxo0y	231	43	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	231	44	challenge	challenge	NN
cord-293701-u4ntxo0y	231	45	in	in	IN
cord-293701-u4ntxo0y	231	46	the	the	DT
cord-293701-u4ntxo0y	231	47	former	former	JJ
cord-293701-u4ntxo0y	231	48	model	model	NN
cord-293701-u4ntxo0y	231	49	133	133	CD
cord-293701-u4ntxo0y	231	50	.	.	.
cord-293701-u4ntxo0y	232	1	In	in	IN
cord-293701-u4ntxo0y	232	2	addition	addition	NN
cord-293701-u4ntxo0y	232	3	,	,	,
cord-293701-u4ntxo0y	232	4	several	several	JJ
cord-293701-u4ntxo0y	232	5	groups	group	NNS
cord-293701-u4ntxo0y	232	6	have	have	VBP
cord-293701-u4ntxo0y	232	7	reported	report	VBN
cord-293701-u4ntxo0y	232	8	the	the	DT
cord-293701-u4ntxo0y	232	9	identification	identification	NN
cord-293701-u4ntxo0y	232	10	of	of	IN
cord-293701-u4ntxo0y	232	11	RBD	RBD	NNP
cord-293701-u4ntxo0y	232	12	-	-	HYPH
cord-293701-u4ntxo0y	232	13	targeting	targeting	NN
cord-293701-u4ntxo0y	232	14	and	and	CC
cord-293701-u4ntxo0y	232	15	cross	cross	JJ
cord-293701-u4ntxo0y	232	16	-	-	JJ
cord-293701-u4ntxo0y	232	17	reactive	reactive	JJ
cord-293701-u4ntxo0y	232	18	antibodies	antibody	NNS
cord-293701-u4ntxo0y	232	19	to	to	IN
cord-293701-u4ntxo0y	232	20	SARS	SARS	NNP
cord-293701-u4ntxo0y	232	21	-	-	HYPH
cord-293701-u4ntxo0y	232	22	CoV	CoV	NNP
cord-293701-u4ntxo0y	232	23	and	and	CC
cord-293701-u4ntxo0y	232	24	other	other	JJ
cord-293701-u4ntxo0y	232	25	human	human	JJ
cord-293701-u4ntxo0y	232	26	coronaviruses	coronaviruse	NNS
cord-293701-u4ntxo0y	232	27	,	,	,
cord-293701-u4ntxo0y	232	28	indicating	indicate	VBG
cord-293701-u4ntxo0y	232	29	that	that	IN
cord-293701-u4ntxo0y	232	30	some	some	DT
cord-293701-u4ntxo0y	232	31	conserved	conserved	JJ
cord-293701-u4ntxo0y	232	32	epitopes	epitope	NNS
cord-293701-u4ntxo0y	232	33	may	may	MD
cord-293701-u4ntxo0y	232	34	exist	exist	VB
cord-293701-u4ntxo0y	232	35	in	in	IN
cord-293701-u4ntxo0y	232	36	RBD	RBD	NNP
cord-293701-u4ntxo0y	232	37	.	.	.
cord-293701-u4ntxo0y	233	1	A	a	DT
cord-293701-u4ntxo0y	233	2	study	study	NN
cord-293701-u4ntxo0y	233	3	identified	identify	VBD
cord-293701-u4ntxo0y	233	4	eight	eight	CD
cord-293701-u4ntxo0y	233	5	RBD	RBD	NNP
cord-293701-u4ntxo0y	233	6	-	-	HYPH
cord-293701-u4ntxo0y	233	7	targeted	target	VBN
cord-293701-u4ntxo0y	233	8	antibodies	antibody	NNS
cord-293701-u4ntxo0y	233	9	derived	derive	VBN
cord-293701-u4ntxo0y	233	10	from	from	IN
cord-293701-u4ntxo0y	233	11	patients	patient	NNS
cord-293701-u4ntxo0y	233	12	with	with	IN
cord-293701-u4ntxo0y	233	13	SERS	SERS	NNP
cord-293701-u4ntxo0y	233	14	that	that	WDT
cord-293701-u4ntxo0y	233	15	neutralized	neutralize	VBD
cord-293701-u4ntxo0y	233	16	authentic	authentic	JJ
cord-293701-u4ntxo0y	233	17	SARS	SARS	NNP
cord-293701-u4ntxo0y	233	18	-	-	HYPH
cord-293701-u4ntxo0y	233	19	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	233	20	,	,	,
cord-293701-u4ntxo0y	233	21	SARS	SARS	NNP
cord-293701-u4ntxo0y	233	22	-	-	HYPH
cord-293701-u4ntxo0y	233	23	CoV	CoV	NNP
cord-293701-u4ntxo0y	233	24	and	and	CC
cord-293701-u4ntxo0y	233	25	WIV1	WIV1	NNP
cord-293701-u4ntxo0y	233	26	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	233	27	with	with	IN
cord-293701-u4ntxo0y	233	28	half	half	PDT
cord-293701-u4ntxo0y	233	29	maximal	maximal	JJ
cord-293701-u4ntxo0y	233	30	inhibitory	inhibitory	JJ
cord-293701-u4ntxo0y	233	31	concentrations	concentration	NNS
cord-293701-u4ntxo0y	233	32	of	of	IN
cord-293701-u4ntxo0y	233	33	0.05	0.05	CD
cord-293701-u4ntxo0y	233	34	-	-	SYM
cord-293701-u4ntxo0y	233	35	1.4	1.4	CD
cord-293701-u4ntxo0y	233	36	,	,	,
cord-293701-u4ntxo0y	233	37	0.004	0.004	CD
cord-293701-u4ntxo0y	233	38	-	-	HYPH
cord-293701-u4ntxo0y	233	39	0.06	0.06	CD
cord-293701-u4ntxo0y	233	40	and	and	CC
cord-293701-u4ntxo0y	233	41	0.076	0.076	CD
cord-293701-u4ntxo0y	233	42	-	-	SYM
cord-293701-u4ntxo0y	233	43	1.7	1.7	CD
cord-293701-u4ntxo0y	233	44	μg	μg	NNP
cord-293701-u4ntxo0y	233	45	ml	ml	NNP
cord-293701-u4ntxo0y	233	46	−1	−1	NNP
cord-293701-u4ntxo0y	233	47	,	,	,
cord-293701-u4ntxo0y	233	48	respectively	respectively	RB
cord-293701-u4ntxo0y	233	49	134	134	CD
cord-293701-u4ntxo0y	233	50	.	.	.
cord-293701-u4ntxo0y	234	1	Another	another	DT
cord-293701-u4ntxo0y	234	2	study	study	NN
cord-293701-u4ntxo0y	234	3	isolated	isolate	VBD
cord-293701-u4ntxo0y	234	4	an	an	DT
cord-293701-u4ntxo0y	234	5	RBD	RBD	NNP
cord-293701-u4ntxo0y	234	6	-	-	HYPH
cord-293701-u4ntxo0y	234	7	specific	specific	JJ
cord-293701-u4ntxo0y	234	8	antibody	antibody	NN
cord-293701-u4ntxo0y	234	9	,	,	,
cord-293701-u4ntxo0y	234	10	S309	S309	NNP
cord-293701-u4ntxo0y	234	11	,	,	,
cord-293701-u4ntxo0y	234	12	from	from	IN
cord-293701-u4ntxo0y	234	13	memory	memory	NN
cord-293701-u4ntxo0y	234	14	B	b	NN
cord-293701-u4ntxo0y	234	15	cells	cell	NNS
cord-293701-u4ntxo0y	234	16	of	of	IN
cord-293701-u4ntxo0y	234	17	a	a	DT
cord-293701-u4ntxo0y	234	18	patient	patient	NN
cord-293701-u4ntxo0y	234	19	with	with	IN
cord-293701-u4ntxo0y	234	20	SARS	SARS	NNP
cord-293701-u4ntxo0y	234	21	.	.	.
cord-293701-u4ntxo0y	235	1	It	-PRON-	PRP
cord-293701-u4ntxo0y	235	2	potently	potently	RB
cord-293701-u4ntxo0y	235	3	neutralized	neutralize	VBD
cord-293701-u4ntxo0y	235	4	SARS	SARS	NNP
cord-293701-u4ntxo0y	235	5	-	-	HYPH
cord-293701-u4ntxo0y	235	6	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	235	7	and	and	CC
cord-293701-u4ntxo0y	235	8	SARS	SARS	NNP
cord-293701-u4ntxo0y	235	9	-	-	HYPH
cord-293701-u4ntxo0y	235	10	CoV	CoV	NNP
cord-293701-u4ntxo0y	235	11	infection	infection	NN
cord-293701-u4ntxo0y	235	12	135	135	CD
cord-293701-u4ntxo0y	235	13	.	.	.
cord-293701-u4ntxo0y	236	1	The	the	DT
cord-293701-u4ntxo0y	236	2	RBD	RBD	NNP
cord-293701-u4ntxo0y	236	3	from	from	IN
cord-293701-u4ntxo0y	236	4	a	a	DT
cord-293701-u4ntxo0y	236	5	human	human	JJ
cord-293701-u4ntxo0y	236	6	strain	strain	NN
cord-293701-u4ntxo0y	236	7	(	(	-LRB-
cord-293701-u4ntxo0y	236	8	GD03	GD03	NNP
cord-293701-u4ntxo0y	236	9	)	)	-RRB-
cord-293701-u4ntxo0y	236	10	and	and	CC
cord-293701-u4ntxo0y	236	11	a	a	DT
cord-293701-u4ntxo0y	236	12	palm	palm	NN
cord-293701-u4ntxo0y	236	13	civet	civet	NN
cord-293701-u4ntxo0y	236	14	strain	strain	NN
cord-293701-u4ntxo0y	236	15	(	(	-LRB-
cord-293701-u4ntxo0y	236	16	SZ16	SZ16	NNP
cord-293701-u4ntxo0y	236	17	)	)	-RRB-
cord-293701-u4ntxo0y	236	18	of	of	IN
cord-293701-u4ntxo0y	236	19	SARS	SARS	NNP
cord-293701-u4ntxo0y	236	20	-	-	HYPH
cord-293701-u4ntxo0y	236	21	CoV	CoV	NNP
cord-293701-u4ntxo0y	236	22	elicited	elicit	VBD
cord-293701-u4ntxo0y	236	23	antibodies	antibody	NNS
cord-293701-u4ntxo0y	236	24	in	in	IN
cord-293701-u4ntxo0y	236	25	rabbits	rabbit	NNS
cord-293701-u4ntxo0y	236	26	that	that	WDT
cord-293701-u4ntxo0y	236	27	strongly	strongly	RB
cord-293701-u4ntxo0y	236	28	reacted	react	VBD
cord-293701-u4ntxo0y	236	29	with	with	IN
cord-293701-u4ntxo0y	236	30	and	and	CC
cord-293701-u4ntxo0y	236	31	potently	potently	RB
cord-293701-u4ntxo0y	236	32	neutralized	neutralize	VBN
cord-293701-u4ntxo0y	236	33	SARS	SARS	NNP
cord-293701-u4ntxo0y	236	34	-	-	HYPH
cord-293701-u4ntxo0y	236	35	CoV	CoV	NNP
cord-293701-u4ntxo0y	236	36	and	and	CC
cord-293701-u4ntxo0y	236	37	SARS	SARS	NNP
cord-293701-u4ntxo0y	236	38	-	-	HYPH
cord-293701-u4ntxo0y	236	39	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	236	40	,	,	,
cord-293701-u4ntxo0y	236	41	indicating	indicate	VBG
cord-293701-u4ntxo0y	236	42	that	that	IN
cord-293701-u4ntxo0y	236	43	the	the	DT
cord-293701-u4ntxo0y	236	44	RBD	RBD	NNP
cord-293701-u4ntxo0y	236	45	can	can	MD
cord-293701-u4ntxo0y	236	46	induce	induce	VB
cord-293701-u4ntxo0y	236	47	cross	cross	JJ
cord-293701-u4ntxo0y	236	48	-	-	JJ
cord-293701-u4ntxo0y	236	49	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	236	50	antibodies	antibody	NNS
cord-293701-u4ntxo0y	236	51	to	to	IN
cord-293701-u4ntxo0y	236	52	both	both	DT
cord-293701-u4ntxo0y	236	53	SARS	SARS	NNP
cord-293701-u4ntxo0y	236	54	-	-	HYPH
cord-293701-u4ntxo0y	236	55	CoV	CoV	NNP
cord-293701-u4ntxo0y	236	56	and	and	CC
cord-293701-u4ntxo0y	236	57	SARS	SARS	NNP
cord-293701-u4ntxo0y	236	58	-	-	HYPH
cord-293701-u4ntxo0y	236	59	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	236	60	(	(	-LRB-
cord-293701-u4ntxo0y	236	61	ref	ref	NN
cord-293701-u4ntxo0y	236	62	.	.	.
cord-293701-u4ntxo0y	236	63	136	136	CD
cord-293701-u4ntxo0y	236	64	)	)	-RRB-
cord-293701-u4ntxo0y	236	65	.	.	.
cord-293701-u4ntxo0y	237	1	These	these	DT
cord-293701-u4ntxo0y	237	2	studies	study	NNS
cord-293701-u4ntxo0y	237	3	further	far	RBR
cord-293701-u4ntxo0y	237	4	support	support	VBP
cord-293701-u4ntxo0y	237	5	the	the	DT
cord-293701-u4ntxo0y	237	6	development	development	NN
cord-293701-u4ntxo0y	237	7	of	of	IN
cord-293701-u4ntxo0y	237	8	RBD	RBD	NNP
cord-293701-u4ntxo0y	237	9	-	-	HYPH
cord-293701-u4ntxo0y	237	10	based	base	VBN
cord-293701-u4ntxo0y	237	11	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	237	12	.	.	.
cord-293701-u4ntxo0y	238	1	Optimization	optimization	NN
cord-293701-u4ntxo0y	238	2	of	of	IN
cord-293701-u4ntxo0y	238	3	the	the	DT
cord-293701-u4ntxo0y	238	4	RBD	RBD	NNP
cord-293701-u4ntxo0y	238	5	by	by	IN
cord-293701-u4ntxo0y	238	6	covering	cover	VBG
cord-293701-u4ntxo0y	238	7	the	the	DT
cord-293701-u4ntxo0y	238	8	non	non	JJ
cord-293701-u4ntxo0y	238	9	-	-	JJ
cord-293701-u4ntxo0y	238	10	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	238	11	antibody	antibody	NN
cord-293701-u4ntxo0y	238	12	epitopes	epitope	NNS
cord-293701-u4ntxo0y	238	13	with	with	IN
cord-293701-u4ntxo0y	238	14	glycosylation	glycosylation	NN
cord-293701-u4ntxo0y	238	15	137	137	CD
cord-293701-u4ntxo0y	238	16	and	and	CC
cord-293701-u4ntxo0y	238	17	exposing	expose	VBG
cord-293701-u4ntxo0y	238	18	the	the	DT
cord-293701-u4ntxo0y	238	19	NAb	NAb	NNS
cord-293701-u4ntxo0y	238	20	epitopes	epitope	NNS
cord-293701-u4ntxo0y	238	21	with	with	IN
cord-293701-u4ntxo0y	238	22	deglycosylation	deglycosylation	NN
cord-293701-u4ntxo0y	238	23	138	138	CD
cord-293701-u4ntxo0y	238	24	is	be	VBZ
cord-293701-u4ntxo0y	238	25	expected	expect	VBN
cord-293701-u4ntxo0y	238	26	to	to	TO
cord-293701-u4ntxo0y	238	27	enhance	enhance	VB
cord-293701-u4ntxo0y	238	28	its	-PRON-	PRP$
cord-293701-u4ntxo0y	238	29	protective	protective	JJ
cord-293701-u4ntxo0y	238	30	immunity	immunity	NN
cord-293701-u4ntxo0y	238	31	and	and	CC
cord-293701-u4ntxo0y	238	32	reduce	reduce	VB
cord-293701-u4ntxo0y	238	33	its	-PRON-	PRP$
cord-293701-u4ntxo0y	238	34	potential	potential	NN
cord-293701-u4ntxo0y	238	35	to	to	TO
cord-293701-u4ntxo0y	238	36	induce	induce	VB
cord-293701-u4ntxo0y	238	37	non	non	JJ
cord-293701-u4ntxo0y	238	38	-	-	JJ
cord-293701-u4ntxo0y	238	39	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	238	40	antibodies	antibody	NNS
cord-293701-u4ntxo0y	238	41	,	,	,
cord-293701-u4ntxo0y	238	42	suggesting	suggest	VBG
cord-293701-u4ntxo0y	238	43	that	that	IN
cord-293701-u4ntxo0y	238	44	an	an	DT
cord-293701-u4ntxo0y	238	45	optimized	optimize	VBN
cord-293701-u4ntxo0y	238	46	RBD	RBD	NNP
cord-293701-u4ntxo0y	238	47	is	be	VBZ
cord-293701-u4ntxo0y	238	48	an	an	DT
cord-293701-u4ntxo0y	238	49	ideal	ideal	JJ
cord-293701-u4ntxo0y	238	50	antigen	antigen	NN
cord-293701-u4ntxo0y	238	51	for	for	IN
cord-293701-u4ntxo0y	238	52	development	development	NN
cord-293701-u4ntxo0y	238	53	of	of	IN
cord-293701-u4ntxo0y	238	54	safe	safe	JJ
cord-293701-u4ntxo0y	238	55	and	and	CC
cord-293701-u4ntxo0y	238	56	effective	effective	JJ
cord-293701-u4ntxo0y	238	57	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	238	58	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	238	59	,	,	,
cord-293701-u4ntxo0y	238	60	although	although	IN
cord-293701-u4ntxo0y	238	61	other	other	JJ
cord-293701-u4ntxo0y	238	62	approaches	approach	NNS
cord-293701-u4ntxo0y	238	63	might	may	MD
cord-293701-u4ntxo0y	238	64	also	also	RB
cord-293701-u4ntxo0y	238	65	turn	turn	VB
cord-293701-u4ntxo0y	238	66	out	out	RP
cord-293701-u4ntxo0y	238	67	to	to	TO
cord-293701-u4ntxo0y	238	68	be	be	VB
cord-293701-u4ntxo0y	238	69	safe	safe	JJ
cord-293701-u4ntxo0y	238	70	and	and	CC
cord-293701-u4ntxo0y	238	71	effective	effective	JJ
cord-293701-u4ntxo0y	238	72	.	.	.
cord-293701-u4ntxo0y	239	1	In	in	IN
cord-293701-u4ntxo0y	239	2	May	May	NNP
cord-293701-u4ntxo0y	239	3	1796	1796	CD
cord-293701-u4ntxo0y	239	4	,	,	,
cord-293701-u4ntxo0y	239	5	a	a	DT
cord-293701-u4ntxo0y	239	6	little	little	JJ
cord-293701-u4ntxo0y	239	7	boy	boy	NN
cord-293701-u4ntxo0y	239	8	was	be	VBD
cord-293701-u4ntxo0y	239	9	inoculated	inoculate	VBN
cord-293701-u4ntxo0y	239	10	with	with	IN
cord-293701-u4ntxo0y	239	11	the	the	DT
cord-293701-u4ntxo0y	239	12	fester	fester	NN
cord-293701-u4ntxo0y	239	13	from	from	IN
cord-293701-u4ntxo0y	239	14	a	a	DT
cord-293701-u4ntxo0y	239	15	cowpox	cowpox	NN
cord-293701-u4ntxo0y	239	16	-	-	HYPH
cord-293701-u4ntxo0y	239	17	infected	infect	VBN
cord-293701-u4ntxo0y	239	18	patient	patient	NN
cord-293701-u4ntxo0y	239	19	,	,	,
cord-293701-u4ntxo0y	239	20	thus	thus	RB
cord-293701-u4ntxo0y	239	21	initiating	initiate	VBG
cord-293701-u4ntxo0y	239	22	the	the	DT
cord-293701-u4ntxo0y	239	23	history	history	NN
cord-293701-u4ntxo0y	239	24	of	of	IN
cord-293701-u4ntxo0y	239	25	vaccination	vaccination	NN
cord-293701-u4ntxo0y	239	26	.	.	.
cord-293701-u4ntxo0y	240	1	From	from	IN
cord-293701-u4ntxo0y	240	2	then	then	RB
cord-293701-u4ntxo0y	240	3	on	on	RB
cord-293701-u4ntxo0y	240	4	,	,	,
cord-293701-u4ntxo0y	240	5	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	240	6	have	have	VBP
cord-293701-u4ntxo0y	240	7	been	be	VBN
cord-293701-u4ntxo0y	240	8	instrumental	instrumental	JJ
cord-293701-u4ntxo0y	240	9	in	in	IN
cord-293701-u4ntxo0y	240	10	combating	combat	VBG
cord-293701-u4ntxo0y	240	11	many	many	JJ
cord-293701-u4ntxo0y	240	12	viral	viral	JJ
cord-293701-u4ntxo0y	240	13	diseases	disease	NNS
cord-293701-u4ntxo0y	240	14	,	,	,
cord-293701-u4ntxo0y	240	15	such	such	JJ
cord-293701-u4ntxo0y	240	16	as	as	IN
cord-293701-u4ntxo0y	240	17	smallpox	smallpox	NN
cord-293701-u4ntxo0y	240	18	,	,	,
cord-293701-u4ntxo0y	240	19	rabies	rabies	NN
cord-293701-u4ntxo0y	240	20	and	and	CC
cord-293701-u4ntxo0y	240	21	polio	polio	NN
cord-293701-u4ntxo0y	240	22	.	.	.
cord-293701-u4ntxo0y	241	1	The	the	DT
cord-293701-u4ntxo0y	241	2	phenomenon	phenomenon	NN
cord-293701-u4ntxo0y	241	3	of	of	IN
cord-293701-u4ntxo0y	241	4	VADE	VADE	NNP
cord-293701-u4ntxo0y	241	5	has	have	VBZ
cord-293701-u4ntxo0y	241	6	,	,	,
cord-293701-u4ntxo0y	241	7	however	however	RB
cord-293701-u4ntxo0y	241	8	,	,	,
cord-293701-u4ntxo0y	241	9	erected	erect	VBD
cord-293701-u4ntxo0y	241	10	substantial	substantial	JJ
cord-293701-u4ntxo0y	241	11	barriers	barrier	NNS
cord-293701-u4ntxo0y	241	12	to	to	IN
cord-293701-u4ntxo0y	241	13	the	the	DT
cord-293701-u4ntxo0y	241	14	development	development	NN
cord-293701-u4ntxo0y	241	15	of	of	IN
cord-293701-u4ntxo0y	241	16	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	241	17	for	for	IN
cord-293701-u4ntxo0y	241	18	some	some	DT
cord-293701-u4ntxo0y	241	19	viruses	virus	NNS
cord-293701-u4ntxo0y	241	20	,	,	,
cord-293701-u4ntxo0y	241	21	including	include	VBG
cord-293701-u4ntxo0y	241	22	,	,	,
cord-293701-u4ntxo0y	241	23	RSV	RSV	NNP
cord-293701-u4ntxo0y	241	24	,	,	,
cord-293701-u4ntxo0y	241	25	DENV	DENV	NNP
cord-293701-u4ntxo0y	241	26	,	,	,
cord-293701-u4ntxo0y	241	27	SARS	SARS	NNP
cord-293701-u4ntxo0y	241	28	-	-	HYPH
cord-293701-u4ntxo0y	241	29	CoV	CoV	NNP
cord-293701-u4ntxo0y	241	30	and	and	CC
cord-293701-u4ntxo0y	241	31	MERS	MERS	NNP
cord-293701-u4ntxo0y	241	32	-	-	HYPH
cord-293701-u4ntxo0y	241	33	CoV.	CoV.	NNP
cord-293701-u4ntxo0y	242	1	Currently	currently	RB
cord-293701-u4ntxo0y	242	2	,	,	,
cord-293701-u4ntxo0y	242	3	the	the	DT
cord-293701-u4ntxo0y	242	4	unabated	unabated	JJ
cord-293701-u4ntxo0y	242	5	spread	spread	NN
cord-293701-u4ntxo0y	242	6	of	of	IN
cord-293701-u4ntxo0y	242	7	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	242	8	has	have	VBZ
cord-293701-u4ntxo0y	242	9	prompted	prompt	VBN
cord-293701-u4ntxo0y	242	10	several	several	JJ
cord-293701-u4ntxo0y	242	11	countries	country	NNS
cord-293701-u4ntxo0y	242	12	to	to	TO
cord-293701-u4ntxo0y	242	13	rush	rush	VB
cord-293701-u4ntxo0y	242	14	into	into	IN
cord-293701-u4ntxo0y	242	15	local	local	JJ
cord-293701-u4ntxo0y	242	16	vaccine	vaccine	NN
cord-293701-u4ntxo0y	242	17	approval	approval	NN
cord-293701-u4ntxo0y	242	18	without	without	IN
cord-293701-u4ntxo0y	242	19	a	a	DT
cord-293701-u4ntxo0y	242	20	comprehensive	comprehensive	JJ
cord-293701-u4ntxo0y	242	21	safety	safety	NN
cord-293701-u4ntxo0y	242	22	evaluation	evaluation	NN
cord-293701-u4ntxo0y	242	23	.	.	.
cord-293701-u4ntxo0y	243	1	Vaccines	vaccine	NNS
cord-293701-u4ntxo0y	243	2	for	for	IN
cord-293701-u4ntxo0y	243	3	viruses	virus	NNS
cord-293701-u4ntxo0y	243	4	with	with	IN
cord-293701-u4ntxo0y	243	5	high	high	JJ
cord-293701-u4ntxo0y	243	6	transmissibility	transmissibility	NN
cord-293701-u4ntxo0y	243	7	but	but	CC
cord-293701-u4ntxo0y	243	8	low	low	JJ
cord-293701-u4ntxo0y	243	9	case	case	NN
cord-293701-u4ntxo0y	243	10	fatality	fatality	NN
cord-293701-u4ntxo0y	243	11	,	,	,
cord-293701-u4ntxo0y	243	12	such	such	JJ
cord-293701-u4ntxo0y	243	13	as	as	IN
cord-293701-u4ntxo0y	243	14	SARS	SARS	NNP
cord-293701-u4ntxo0y	243	15	-	-	HYPH
cord-293701-u4ntxo0y	243	16	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	243	17	,	,	,
cord-293701-u4ntxo0y	243	18	should	should	MD
cord-293701-u4ntxo0y	243	19	usually	usually	RB
cord-293701-u4ntxo0y	243	20	have	have	VB
cord-293701-u4ntxo0y	243	21	a	a	DT
cord-293701-u4ntxo0y	243	22	higher	high	JJR
cord-293701-u4ntxo0y	243	23	www.nature.com/nrmicro	www.nature.com/nrmicro	NNP
cord-293701-u4ntxo0y	243	24	bar	bar	NN
cord-293701-u4ntxo0y	243	25	for	for	IN
cord-293701-u4ntxo0y	243	26	safety	safety	NN
cord-293701-u4ntxo0y	243	27	than	than	IN
cord-293701-u4ntxo0y	243	28	those	those	DT
cord-293701-u4ntxo0y	243	29	for	for	IN
cord-293701-u4ntxo0y	243	30	viruses	virus	NNS
cord-293701-u4ntxo0y	243	31	with	with	IN
cord-293701-u4ntxo0y	243	32	low	low	JJ
cord-293701-u4ntxo0y	243	33	transmissibility	transmissibility	NN
cord-293701-u4ntxo0y	243	34	but	but	CC
cord-293701-u4ntxo0y	243	35	high	high	JJ
cord-293701-u4ntxo0y	243	36	case	case	NN
cord-293701-u4ntxo0y	243	37	fatality	fatality	NN
cord-293701-u4ntxo0y	243	38	,	,	,
cord-293701-u4ntxo0y	243	39	such	such	JJ
cord-293701-u4ntxo0y	243	40	as	as	IN
cord-293701-u4ntxo0y	243	41	Ebola	Ebola	NNP
cord-293701-u4ntxo0y	243	42	virus	virus	NN
cord-293701-u4ntxo0y	243	43	,	,	,
cord-293701-u4ntxo0y	243	44	because	because	IN
cord-293701-u4ntxo0y	243	45	many	many	JJ
cord-293701-u4ntxo0y	243	46	more	more	RBR
cord-293701-u4ntxo0y	243	47	healthy	healthy	JJ
cord-293701-u4ntxo0y	243	48	individuals	individual	NNS
cord-293701-u4ntxo0y	243	49	will	will	MD
cord-293701-u4ntxo0y	243	50	have	have	VB
cord-293701-u4ntxo0y	243	51	to	to	TO
cord-293701-u4ntxo0y	243	52	use	use	VB
cord-293701-u4ntxo0y	243	53	them	-PRON-	PRP
cord-293701-u4ntxo0y	243	54	.	.	.
cord-293701-u4ntxo0y	244	1	On	on	IN
cord-293701-u4ntxo0y	244	2	15	15	CD
cord-293701-u4ntxo0y	244	3	July	July	NNP
cord-293701-u4ntxo0y	244	4	2020	2020	CD
cord-293701-u4ntxo0y	244	5	,	,	,
cord-293701-u4ntxo0y	244	6	the	the	DT
cord-293701-u4ntxo0y	244	7	WHO	who	WP
cord-293701-u4ntxo0y	244	8	announced	announce	VBD
cord-293701-u4ntxo0y	244	9	that	that	IN
cord-293701-u4ntxo0y	244	10	more	more	JJR
cord-293701-u4ntxo0y	244	11	than	than	IN
cord-293701-u4ntxo0y	244	12	150	150	CD
cord-293701-u4ntxo0y	244	13	countries	country	NNS
cord-293701-u4ntxo0y	244	14	are	be	VBP
cord-293701-u4ntxo0y	244	15	engaged	engage	VBN
cord-293701-u4ntxo0y	244	16	in	in	IN
cord-293701-u4ntxo0y	244	17	the	the	DT
cord-293701-u4ntxo0y	244	18	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	244	19	Vaccine	Vaccine	NNP
cord-293701-u4ntxo0y	244	20	Global	Global	NNP
cord-293701-u4ntxo0y	244	21	Access	Access	NNP
cord-293701-u4ntxo0y	244	22	(	(	-LRB-
cord-293701-u4ntxo0y	244	23	COVAX	COVAX	NNP
cord-293701-u4ntxo0y	244	24	)	)	-RRB-
cord-293701-u4ntxo0y	244	25	initiative	initiative	NN
cord-293701-u4ntxo0y	244	26	,	,	,
cord-293701-u4ntxo0y	244	27	a	a	DT
cord-293701-u4ntxo0y	244	28	mechanism	mechanism	NN
cord-293701-u4ntxo0y	244	29	designed	design	VBN
cord-293701-u4ntxo0y	244	30	to	to	TO
cord-293701-u4ntxo0y	244	31	guarantee	guarantee	VB
cord-293701-u4ntxo0y	244	32	rapid	rapid	JJ
cord-293701-u4ntxo0y	244	33	,	,	,
cord-293701-u4ntxo0y	244	34	fair	fair	JJ
cord-293701-u4ntxo0y	244	35	and	and	CC
cord-293701-u4ntxo0y	244	36	equitable	equitable	JJ
cord-293701-u4ntxo0y	244	37	access	access	NN
cord-293701-u4ntxo0y	244	38	to	to	IN
cord-293701-u4ntxo0y	244	39	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	244	40	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	244	41	worldwide	worldwide	RB
cord-293701-u4ntxo0y	244	42	139	139	CD
cord-293701-u4ntxo0y	244	43	.	.	.
cord-293701-u4ntxo0y	245	1	This	this	DT
cord-293701-u4ntxo0y	245	2	further	further	RB
cord-293701-u4ntxo0y	245	3	raises	raise	VBZ
cord-293701-u4ntxo0y	245	4	the	the	DT
cord-293701-u4ntxo0y	245	5	safety	safety	NN
cord-293701-u4ntxo0y	245	6	bar	bar	NN
cord-293701-u4ntxo0y	245	7	for	for	IN
cord-293701-u4ntxo0y	245	8	a	a	DT
cord-293701-u4ntxo0y	245	9	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	245	10	vaccine	vaccine	NN
cord-293701-u4ntxo0y	245	11	as	as	IN
cord-293701-u4ntxo0y	245	12	it	-PRON-	PRP
cord-293701-u4ntxo0y	245	13	should	should	MD
cord-293701-u4ntxo0y	245	14	be	be	VB
cord-293701-u4ntxo0y	245	15	safe	safe	JJ
cord-293701-u4ntxo0y	245	16	for	for	IN
cord-293701-u4ntxo0y	245	17	all	all	DT
cord-293701-u4ntxo0y	245	18	people	people	NNS
cord-293701-u4ntxo0y	245	19	in	in	IN
cord-293701-u4ntxo0y	245	20	the	the	DT
cord-293701-u4ntxo0y	245	21	world	world	NN
cord-293701-u4ntxo0y	245	22	,	,	,
cord-293701-u4ntxo0y	245	23	irrespective	irrespective	RB
cord-293701-u4ntxo0y	245	24	of	of	IN
cord-293701-u4ntxo0y	245	25	age	age	NN
cord-293701-u4ntxo0y	245	26	,	,	,
cord-293701-u4ntxo0y	245	27	gender	gender	NN
cord-293701-u4ntxo0y	245	28	,	,	,
cord-293701-u4ntxo0y	245	29	race	race	NN
cord-293701-u4ntxo0y	245	30	and	and	CC
cord-293701-u4ntxo0y	245	31	those	those	DT
cord-293701-u4ntxo0y	245	32	with	with	IN
cord-293701-u4ntxo0y	245	33	or	or	CC
cord-293701-u4ntxo0y	245	34	without	without	IN
cord-293701-u4ntxo0y	245	35	co	co	NNS
cord-293701-u4ntxo0y	245	36	-	-	NNS
cord-293701-u4ntxo0y	245	37	morbidities	morbidity	NNS
cord-293701-u4ntxo0y	245	38	.	.	.
cord-293701-u4ntxo0y	246	1	If	if	IN
cord-293701-u4ntxo0y	246	2	the	the	DT
cord-293701-u4ntxo0y	246	3	adverse	adverse	JJ
cord-293701-u4ntxo0y	246	4	reaction	reaction	NN
cord-293701-u4ntxo0y	246	5	rate	rate	NN
cord-293701-u4ntxo0y	246	6	of	of	IN
cord-293701-u4ntxo0y	246	7	a	a	DT
cord-293701-u4ntxo0y	246	8	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	246	9	vaccine	vaccine	NN
cord-293701-u4ntxo0y	246	10	is	be	VBZ
cord-293701-u4ntxo0y	246	11	only	only	RB
cord-293701-u4ntxo0y	246	12	1	1	CD
cord-293701-u4ntxo0y	246	13	%	%	NN
cord-293701-u4ntxo0y	246	14	,	,	,
cord-293701-u4ntxo0y	246	15	about	about	RB
cord-293701-u4ntxo0y	246	16	78	78	CD
cord-293701-u4ntxo0y	246	17	million	million	CD
cord-293701-u4ntxo0y	246	18	individuals	individual	NNS
cord-293701-u4ntxo0y	246	19	will	will	MD
cord-293701-u4ntxo0y	246	20	be	be	VB
cord-293701-u4ntxo0y	246	21	affected	affect	VBN
cord-293701-u4ntxo0y	246	22	if	if	IN
cord-293701-u4ntxo0y	246	23	the	the	DT
cord-293701-u4ntxo0y	246	24	whole	whole	JJ
cord-293701-u4ntxo0y	246	25	world	world	NN
cord-293701-u4ntxo0y	246	26	population	population	NN
cord-293701-u4ntxo0y	246	27	is	be	VBZ
cord-293701-u4ntxo0y	246	28	vaccinated	vaccinate	VBN
cord-293701-u4ntxo0y	246	29	.	.	.
cord-293701-u4ntxo0y	247	1	The	the	DT
cord-293701-u4ntxo0y	247	2	adverse	adverse	JJ
cord-293701-u4ntxo0y	247	3	reaction	reaction	NN
cord-293701-u4ntxo0y	247	4	rate	rate	NN
cord-293701-u4ntxo0y	247	5	of	of	IN
cord-293701-u4ntxo0y	247	6	a	a	DT
cord-293701-u4ntxo0y	247	7	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	247	8	vaccine	vaccine	NN
cord-293701-u4ntxo0y	247	9	should	should	MD
cord-293701-u4ntxo0y	247	10	be	be	VB
cord-293701-u4ntxo0y	247	11	kept	keep	VBN
cord-293701-u4ntxo0y	247	12	extremely	extremely	RB
cord-293701-u4ntxo0y	247	13	low	low	JJ
cord-293701-u4ntxo0y	247	14	if	if	IN
cord-293701-u4ntxo0y	247	15	it	-PRON-	PRP
cord-293701-u4ntxo0y	247	16	is	be	VBZ
cord-293701-u4ntxo0y	247	17	distributed	distribute	VBN
cord-293701-u4ntxo0y	247	18	globally	globally	RB
cord-293701-u4ntxo0y	247	19	.	.	.
cord-293701-u4ntxo0y	248	1	The	the	DT
cord-293701-u4ntxo0y	248	2	comprehensive	comprehensive	JJ
cord-293701-u4ntxo0y	248	3	safety	safety	NN
cord-293701-u4ntxo0y	248	4	evaluation	evaluation	NN
cord-293701-u4ntxo0y	248	5	in	in	IN
cord-293701-u4ntxo0y	248	6	different	different	JJ
cord-293701-u4ntxo0y	248	7	animal	animal	NN
cord-293701-u4ntxo0y	248	8	models	model	NNS
cord-293701-u4ntxo0y	248	9	and	and	CC
cord-293701-u4ntxo0y	248	10	clinical	clinical	JJ
cord-293701-u4ntxo0y	248	11	trials	trial	NNS
cord-293701-u4ntxo0y	248	12	and	and	CC
cord-293701-u4ntxo0y	248	13	rational	rational	JJ
cord-293701-u4ntxo0y	248	14	design	design	NN
cord-293701-u4ntxo0y	248	15	of	of	IN
cord-293701-u4ntxo0y	248	16	antigens	antigen	NNS
cord-293701-u4ntxo0y	248	17	and	and	CC
cord-293701-u4ntxo0y	248	18	adjuvants	adjuvant	NNS
cord-293701-u4ntxo0y	248	19	will	will	MD
cord-293701-u4ntxo0y	248	20	contribute	contribute	VB
cord-293701-u4ntxo0y	248	21	to	to	IN
cord-293701-u4ntxo0y	248	22	lower	low	JJR
cord-293701-u4ntxo0y	248	23	incidence	incidence	NN
cord-293701-u4ntxo0y	248	24	of	of	IN
cord-293701-u4ntxo0y	248	25	VADE	VADE	NNP
cord-293701-u4ntxo0y	248	26	.	.	.
cord-293701-u4ntxo0y	249	1	Jiang	Jiang	NNP
cord-293701-u4ntxo0y	249	2	1	1	CD
cord-293701-u4ntxo0y	249	3	,	,	,
cord-293701-u4ntxo0y	249	4	2	2	CD
cord-293701-u4ntxo0y	249	5	✉	✉	JJ
cord-293701-u4ntxo0y	249	6	 	 	_SP
cord-293701-u4ntxo0y	250	1	Rapid	Rapid	NNP
cord-293701-u4ntxo0y	250	2	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	250	3	vaccine	vaccine	NN
cord-293701-u4ntxo0y	250	4	development	development	NN
cord-293701-u4ntxo0y	251	1	An	an	DT
cord-293701-u4ntxo0y	251	2	mRNA	mrna	NN
cord-293701-u4ntxo0y	251	3	vaccine	vaccine	NN
cord-293701-u4ntxo0y	251	4	against	against	IN
cord-293701-u4ntxo0y	251	5	SARS	SARS	NNP
cord-293701-u4ntxo0y	251	6	-	-	HYPH
cord-293701-u4ntxo0y	251	7	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	252	1	-preliminary	-preliminary	JJ
cord-293701-u4ntxo0y	252	2	report	report	NN
cord-293701-u4ntxo0y	252	3	Safety	Safety	NNP
cord-293701-u4ntxo0y	252	4	,	,	,
cord-293701-u4ntxo0y	252	5	tolerability	tolerability	NN
cord-293701-u4ntxo0y	252	6	,	,	,
cord-293701-u4ntxo0y	252	7	and	and	CC
cord-293701-u4ntxo0y	252	8	immunogenicity	immunogenicity	NN
cord-293701-u4ntxo0y	252	9	of	of	IN
cord-293701-u4ntxo0y	252	10	a	a	DT
cord-293701-u4ntxo0y	252	11	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	252	12	adenovirus	adenovirus	NN
cord-293701-u4ntxo0y	252	13	type-5	type-5	IN
cord-293701-u4ntxo0y	252	14	vectored	vectore	VBN
cord-293701-u4ntxo0y	252	15	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	252	16	vaccine	vaccine	NN
cord-293701-u4ntxo0y	252	17	:	:	:
cord-293701-u4ntxo0y	252	18	a	a	DT
cord-293701-u4ntxo0y	252	19	dose	dose	NN
cord-293701-u4ntxo0y	252	20	-	-	HYPH
cord-293701-u4ntxo0y	252	21	escalation	escalation	NN
cord-293701-u4ntxo0y	252	22	,	,	,
cord-293701-u4ntxo0y	252	23	open	open	JJ
cord-293701-u4ntxo0y	252	24	-	-	HYPH
cord-293701-u4ntxo0y	252	25	label	label	NN
cord-293701-u4ntxo0y	252	26	,	,	,
cord-293701-u4ntxo0y	252	27	non	non	JJ
cord-293701-u4ntxo0y	252	28	-	-	JJ
cord-293701-u4ntxo0y	252	29	randomised	randomised	JJ
cord-293701-u4ntxo0y	252	30	,	,	,
cord-293701-u4ntxo0y	252	31	first	first	JJ
cord-293701-u4ntxo0y	252	32	-	-	HYPH
cord-293701-u4ntxo0y	252	33	in	in	IN
cord-293701-u4ntxo0y	252	34	-	-	HYPH
cord-293701-u4ntxo0y	252	35	human	human	JJ
cord-293701-u4ntxo0y	252	36	trial	trial	NN
cord-293701-u4ntxo0y	252	37	The	the	DT
cord-293701-u4ntxo0y	252	38	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	252	39	vaccine	vaccine	NN
cord-293701-u4ntxo0y	252	40	development	development	NN
cord-293701-u4ntxo0y	252	41	landscape	landscape	NN
cord-293701-u4ntxo0y	252	42	Immunology	Immunology	NNP
cord-293701-u4ntxo0y	252	43	of	of	IN
cord-293701-u4ntxo0y	252	44	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	252	45	:	:	:
cord-293701-u4ntxo0y	252	46	current	current	JJ
cord-293701-u4ntxo0y	252	47	state	state	NN
cord-293701-u4ntxo0y	252	48	of	of	IN
cord-293701-u4ntxo0y	252	49	the	the	DT
cord-293701-u4ntxo0y	252	50	science	science	NN
cord-293701-u4ntxo0y	252	51	Do	do	VBP
cord-293701-u4ntxo0y	252	52	n't	not	RB
cord-293701-u4ntxo0y	252	53	rush	rush	VB
cord-293701-u4ntxo0y	252	54	to	to	TO
cord-293701-u4ntxo0y	252	55	deploy	deploy	VB
cord-293701-u4ntxo0y	252	56	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	252	57	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	252	58	and	and	CC
cord-293701-u4ntxo0y	252	59	drugs	drug	NNS
cord-293701-u4ntxo0y	252	60	without	without	IN
cord-293701-u4ntxo0y	252	61	sufficient	sufficient	JJ
cord-293701-u4ntxo0y	252	62	safety	safety	NN
cord-293701-u4ntxo0y	252	63	guarantees	guarantee	VBZ
cord-293701-u4ntxo0y	252	64	Coronavirus	Coronavirus	NNP
cord-293701-u4ntxo0y	252	65	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	252	66	:	:	:
cord-293701-u4ntxo0y	252	67	five	five	CD
cord-293701-u4ntxo0y	252	68	key	key	JJ
cord-293701-u4ntxo0y	252	69	questions	question	NNS
cord-293701-u4ntxo0y	252	70	as	as	IN
cord-293701-u4ntxo0y	252	71	trials	trial	NNS
cord-293701-u4ntxo0y	252	72	begin	begin	VBP
cord-293701-u4ntxo0y	252	73	SARS	SARS	NNP
cord-293701-u4ntxo0y	252	74	-	-	HYPH
cord-293701-u4ntxo0y	252	75	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	253	1	mRNA	mRNA	NNP
cord-293701-u4ntxo0y	253	2	vaccine	vaccine	NN
cord-293701-u4ntxo0y	253	3	design	design	NN
cord-293701-u4ntxo0y	253	4	enabled	enable	VBN
cord-293701-u4ntxo0y	253	5	by	by	IN
cord-293701-u4ntxo0y	253	6	prototype	prototype	NN
cord-293701-u4ntxo0y	253	7	pathogen	pathogen	NN
cord-293701-u4ntxo0y	253	8	preparedness	preparedness	NN
cord-293701-u4ntxo0y	253	9	Rapid	Rapid	NNP
cord-293701-u4ntxo0y	253	10	development	development	NN
cord-293701-u4ntxo0y	253	11	of	of	IN
cord-293701-u4ntxo0y	253	12	an	an	DT
cord-293701-u4ntxo0y	253	13	inactivated	inactivated	JJ
cord-293701-u4ntxo0y	253	14	vaccine	vaccine	NN
cord-293701-u4ntxo0y	253	15	candidate	candidate	NN
cord-293701-u4ntxo0y	253	16	for	for	IN
cord-293701-u4ntxo0y	253	17	SARS	SARS	NNP
cord-293701-u4ntxo0y	253	18	-	-	HYPH
cord-293701-u4ntxo0y	253	19	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	253	20	Development	Development	NNP
cord-293701-u4ntxo0y	253	21	of	of	IN
cord-293701-u4ntxo0y	253	22	an	an	DT
cord-293701-u4ntxo0y	253	23	inactivated	inactivated	JJ
cord-293701-u4ntxo0y	253	24	vaccine	vaccine	NN
cord-293701-u4ntxo0y	253	25	candidate	candidate	NN
cord-293701-u4ntxo0y	253	26	,	,	,
cord-293701-u4ntxo0y	253	27	BBIBP	BBIBP	NNP
cord-293701-u4ntxo0y	253	28	-	-	HYPH
cord-293701-u4ntxo0y	253	29	CorV	CorV	NNP
cord-293701-u4ntxo0y	253	30	,	,	,
cord-293701-u4ntxo0y	253	31	with	with	IN
cord-293701-u4ntxo0y	253	32	potent	potent	JJ
cord-293701-u4ntxo0y	253	33	protection	protection	NN
cord-293701-u4ntxo0y	253	34	against	against	IN
cord-293701-u4ntxo0y	253	35	SARS	SARS	NNP
cord-293701-u4ntxo0y	253	36	-	-	HYPH
cord-293701-u4ntxo0y	253	37	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	253	38	ChAdOx1	ChAdOx1	NNP
cord-293701-u4ntxo0y	253	39	nCoV-19	ncov-19	DT
cord-293701-u4ntxo0y	253	40	vaccine	vaccine	NN
cord-293701-u4ntxo0y	253	41	prevents	prevent	VBZ
cord-293701-u4ntxo0y	253	42	SARS	SARS	NNP
cord-293701-u4ntxo0y	253	43	-	-	HYPH
cord-293701-u4ntxo0y	253	44	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	253	45	pneumonia	pneumonia	NN
cord-293701-u4ntxo0y	253	46	in	in	IN
cord-293701-u4ntxo0y	253	47	rhesus	rhesu	NNS
cord-293701-u4ntxo0y	253	48	macaques	macaque	NNS
cord-293701-u4ntxo0y	253	49	DNA	DNA	NNP
cord-293701-u4ntxo0y	253	50	vaccine	vaccine	NN
cord-293701-u4ntxo0y	253	51	protection	protection	NN
cord-293701-u4ntxo0y	253	52	against	against	IN
cord-293701-u4ntxo0y	253	53	SARS	SARS	NNP
cord-293701-u4ntxo0y	253	54	-	-	HYPH
cord-293701-u4ntxo0y	253	55	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	253	56	in	in	IN
cord-293701-u4ntxo0y	253	57	rhesus	rhesu	NNS
cord-293701-u4ntxo0y	253	58	macaques	macaque	NNS
cord-293701-u4ntxo0y	253	59	Safety	safety	NN
cord-293701-u4ntxo0y	253	60	and	and	CC
cord-293701-u4ntxo0y	253	61	immunogenicity	immunogenicity	NN
cord-293701-u4ntxo0y	253	62	of	of	IN
cord-293701-u4ntxo0y	253	63	the	the	DT
cord-293701-u4ntxo0y	253	64	ChAdOx1	ChAdOx1	NNP
cord-293701-u4ntxo0y	253	65	nCoV-19	ncov-19	CD
cord-293701-u4ntxo0y	253	66	vaccine	vaccine	NN
cord-293701-u4ntxo0y	253	67	against	against	IN
cord-293701-u4ntxo0y	253	68	SARS	SARS	NNP
cord-293701-u4ntxo0y	253	69	-	-	HYPH
cord-293701-u4ntxo0y	253	70	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	253	71	:	:	:
cord-293701-u4ntxo0y	253	72	a	a	DT
cord-293701-u4ntxo0y	253	73	preliminary	preliminary	JJ
cord-293701-u4ntxo0y	253	74	report	report	NN
cord-293701-u4ntxo0y	253	75	of	of	IN
cord-293701-u4ntxo0y	253	76	a	a	DT
cord-293701-u4ntxo0y	253	77	phase	phase	NN
cord-293701-u4ntxo0y	253	78	1/2	1/2	CD
cord-293701-u4ntxo0y	253	79	,	,	,
cord-293701-u4ntxo0y	253	80	single	single	JJ
cord-293701-u4ntxo0y	253	81	-	-	HYPH
cord-293701-u4ntxo0y	253	82	blind	blind	JJ
cord-293701-u4ntxo0y	253	83	,	,	,
cord-293701-u4ntxo0y	253	84	randomised	randomised	JJ
cord-293701-u4ntxo0y	253	85	controlled	control	VBN
cord-293701-u4ntxo0y	253	86	trial	trial	NN
cord-293701-u4ntxo0y	253	87	Phase	phase	NN
cord-293701-u4ntxo0y	253	88	1/2	1/2	CD
cord-293701-u4ntxo0y	253	89	study	study	NN
cord-293701-u4ntxo0y	253	90	of	of	IN
cord-293701-u4ntxo0y	253	91	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	253	92	RNA	RNA	NNP
cord-293701-u4ntxo0y	253	93	vaccine	vaccine	NN
cord-293701-u4ntxo0y	253	94	BNT162b1	BNT162b1	NNS
cord-293701-u4ntxo0y	253	95	in	in	IN
cord-293701-u4ntxo0y	253	96	adults	adult	NNS
cord-293701-u4ntxo0y	254	1	Concurrent	concurrent	JJ
cord-293701-u4ntxo0y	254	2	human	human	JJ
cord-293701-u4ntxo0y	254	3	antibody	antibody	NN
cord-293701-u4ntxo0y	254	4	and	and	CC
cord-293701-u4ntxo0y	254	5	TH1	TH1	NNP
cord-293701-u4ntxo0y	254	6	type	type	NN
cord-293701-u4ntxo0y	254	7	T	t	NN
cord-293701-u4ntxo0y	254	8	-	-	HYPH
cord-293701-u4ntxo0y	254	9	cell	cell	NN
cord-293701-u4ntxo0y	254	10	responses	response	NNS
cord-293701-u4ntxo0y	254	11	elicited	elicit	VBN
cord-293701-u4ntxo0y	254	12	by	by	IN
cord-293701-u4ntxo0y	254	13	a	a	DT
cord-293701-u4ntxo0y	254	14	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	254	15	RNA	RNA	NNP
cord-293701-u4ntxo0y	254	16	vaccine	vaccine	NN
cord-293701-u4ntxo0y	254	17	The	the	DT
cord-293701-u4ntxo0y	254	18	receptor	receptor	NN
cord-293701-u4ntxo0y	254	19	binding	bind	VBG
cord-293701-u4ntxo0y	254	20	domain	domain	NN
cord-293701-u4ntxo0y	254	21	of	of	IN
cord-293701-u4ntxo0y	254	22	SARS	SARS	NNP
cord-293701-u4ntxo0y	254	23	-	-	HYPH
cord-293701-u4ntxo0y	254	24	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	254	25	spike	spike	NN
cord-293701-u4ntxo0y	254	26	is	be	VBZ
cord-293701-u4ntxo0y	254	27	the	the	DT
cord-293701-u4ntxo0y	254	28	key	key	JJ
cord-293701-u4ntxo0y	254	29	target	target	NN
cord-293701-u4ntxo0y	254	30	of	of	IN
cord-293701-u4ntxo0y	254	31	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	254	32	antibody	antibody	NN
cord-293701-u4ntxo0y	254	33	in	in	IN
cord-293701-u4ntxo0y	254	34	human	human	JJ
cord-293701-u4ntxo0y	254	35	polyclonal	polyclonal	JJ
cord-293701-u4ntxo0y	254	36	sera	sera	NNP
cord-293701-u4ntxo0y	254	37	Safety	Safety	NNP
cord-293701-u4ntxo0y	254	38	and	and	CC
cord-293701-u4ntxo0y	254	39	immunogenicity	immunogenicity	NN
cord-293701-u4ntxo0y	254	40	of	of	IN
cord-293701-u4ntxo0y	254	41	an	an	DT
cord-293701-u4ntxo0y	254	42	rAd26	rad26	NN
cord-293701-u4ntxo0y	254	43	and	and	CC
cord-293701-u4ntxo0y	254	44	rAd5	rad5	PRP$
cord-293701-u4ntxo0y	254	45	vector	vector	NN
cord-293701-u4ntxo0y	254	46	-	-	HYPH
cord-293701-u4ntxo0y	254	47	based	base	VBN
cord-293701-u4ntxo0y	254	48	heterologous	heterologous	JJ
cord-293701-u4ntxo0y	254	49	prime	prime	JJ
cord-293701-u4ntxo0y	254	50	-	-	HYPH
cord-293701-u4ntxo0y	254	51	boost	boost	NN
cord-293701-u4ntxo0y	254	52	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	254	53	vaccine	vaccine	NN
cord-293701-u4ntxo0y	254	54	in	in	IN
cord-293701-u4ntxo0y	254	55	two	two	CD
cord-293701-u4ntxo0y	254	56	formulations	formulation	NNS
cord-293701-u4ntxo0y	254	57	:	:	:
cord-293701-u4ntxo0y	254	58	two	two	CD
cord-293701-u4ntxo0y	254	59	open	open	JJ
cord-293701-u4ntxo0y	254	60	,	,	,
cord-293701-u4ntxo0y	254	61	non	non	JJ
cord-293701-u4ntxo0y	254	62	-	-	JJ
cord-293701-u4ntxo0y	254	63	randomised	randomised	JJ
cord-293701-u4ntxo0y	254	64	phase	phase	NN
cord-293701-u4ntxo0y	254	65	1/2	1/2	CD
cord-293701-u4ntxo0y	254	66	studies	study	NNS
cord-293701-u4ntxo0y	254	67	from	from	IN
cord-293701-u4ntxo0y	254	68	Russia	Russia	NNP
cord-293701-u4ntxo0y	254	69	Enhancement	Enhancement	NNP
cord-293701-u4ntxo0y	254	70	of	of	IN
cord-293701-u4ntxo0y	254	71	the	the	DT
cord-293701-u4ntxo0y	254	72	infectivity	infectivity	NN
cord-293701-u4ntxo0y	254	73	of	of	IN
cord-293701-u4ntxo0y	254	74	arboviruses	arbovirus	NNS
cord-293701-u4ntxo0y	254	75	by	by	IN
cord-293701-u4ntxo0y	254	76	specific	specific	JJ
cord-293701-u4ntxo0y	254	77	antisera	antisera	NN
cord-293701-u4ntxo0y	254	78	produced	produce	VBN
cord-293701-u4ntxo0y	254	79	in	in	IN
cord-293701-u4ntxo0y	254	80	domestic	domestic	JJ
cord-293701-u4ntxo0y	254	81	fowls	fowl	NNS
cord-293701-u4ntxo0y	254	82	Dengue	dengue	NN
cord-293701-u4ntxo0y	254	83	viruses	virus	NNS
cord-293701-u4ntxo0y	254	84	and	and	CC
cord-293701-u4ntxo0y	254	85	mononuclear	mononuclear	JJ
cord-293701-u4ntxo0y	254	86	phagocytes	phagocyte	NNS
cord-293701-u4ntxo0y	254	87	.	.	.
cord-293701-u4ntxo0y	255	1	I.	I.	NNP
cord-293701-u4ntxo0y	255	2	Infection	infection	NN
cord-293701-u4ntxo0y	255	3	enhancement	enhancement	NN
cord-293701-u4ntxo0y	255	4	by	by	IN
cord-293701-u4ntxo0y	255	5	non	non	JJ
cord-293701-u4ntxo0y	255	6	-	-	JJ
cord-293701-u4ntxo0y	255	7	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	255	8	antibody	antibody	NN
cord-293701-u4ntxo0y	255	9	Antibody	antibody	NN
cord-293701-u4ntxo0y	255	10	-	-	HYPH
cord-293701-u4ntxo0y	255	11	mediated	mediate	VBN
cord-293701-u4ntxo0y	255	12	enhancement	enhancement	NN
cord-293701-u4ntxo0y	255	13	of	of	IN
cord-293701-u4ntxo0y	255	14	Flavivirus	Flavivirus	NNP
cord-293701-u4ntxo0y	255	15	replication	replication	NN
cord-293701-u4ntxo0y	255	16	in	in	IN
cord-293701-u4ntxo0y	255	17	macrophagelike	macrophagelike	JJ
cord-293701-u4ntxo0y	255	18	cell	cell	NN
cord-293701-u4ntxo0y	255	19	lines	line	NNS
cord-293701-u4ntxo0y	255	20	Antibody	Antibody	NNP
cord-293701-u4ntxo0y	255	21	-	-	HYPH
cord-293701-u4ntxo0y	255	22	dependent	dependent	JJ
cord-293701-u4ntxo0y	255	23	enhancement	enhancement	NN
cord-293701-u4ntxo0y	255	24	of	of	IN
cord-293701-u4ntxo0y	255	25	human	human	JJ
cord-293701-u4ntxo0y	255	26	immunodeficiency	immunodeficiency	NN
cord-293701-u4ntxo0y	255	27	virus	virus	NN
cord-293701-u4ntxo0y	255	28	type	type	NN
cord-293701-u4ntxo0y	255	29	1	1	CD
cord-293701-u4ntxo0y	255	30	infection	infection	NN
cord-293701-u4ntxo0y	255	31	Infection	infection	NN
cord-293701-u4ntxo0y	255	32	enhancement	enhancement	NN
cord-293701-u4ntxo0y	255	33	of	of	IN
cord-293701-u4ntxo0y	255	34	influenza	influenza	NN
cord-293701-u4ntxo0y	255	35	A	a	DT
cord-293701-u4ntxo0y	255	36	NWS	NWS	NNP
cord-293701-u4ntxo0y	255	37	virus	virus	NN
cord-293701-u4ntxo0y	255	38	in	in	IN
cord-293701-u4ntxo0y	255	39	primary	primary	JJ
cord-293701-u4ntxo0y	255	40	murine	murine	JJ
cord-293701-u4ntxo0y	255	41	macrophages	macrophage	NNS
cord-293701-u4ntxo0y	255	42	by	by	IN
cord-293701-u4ntxo0y	255	43	antihemagglutinin	antihemagglutinin	NNP
cord-293701-u4ntxo0y	255	44	monoclonal	monoclonal	JJ
cord-293701-u4ntxo0y	255	45	antibody	antibody	NN
cord-293701-u4ntxo0y	255	46	Antibody	Antibody	NNP
cord-293701-u4ntxo0y	255	47	-	-	HYPH
cord-293701-u4ntxo0y	255	48	dependent	dependent	JJ
cord-293701-u4ntxo0y	255	49	enhancement	enhancement	NN
cord-293701-u4ntxo0y	255	50	and	and	CC
cord-293701-u4ntxo0y	255	51	SARS	SARS	NNP
cord-293701-u4ntxo0y	255	52	-	-	HYPH
cord-293701-u4ntxo0y	255	53	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	255	54	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	255	55	and	and	CC
cord-293701-u4ntxo0y	255	56	therapies	therapy	NNS
cord-293701-u4ntxo0y	255	57	Anti	anti	JJ
cord-293701-u4ntxo0y	255	58	-	-	JJ
cord-293701-u4ntxo0y	255	59	spike	spike	JJ
cord-293701-u4ntxo0y	255	60	IgG	igg	NN
cord-293701-u4ntxo0y	255	61	causes	cause	VBZ
cord-293701-u4ntxo0y	255	62	severe	severe	JJ
cord-293701-u4ntxo0y	255	63	acute	acute	JJ
cord-293701-u4ntxo0y	255	64	lung	lung	NN
cord-293701-u4ntxo0y	255	65	injury	injury	NN
cord-293701-u4ntxo0y	255	66	by	by	IN
cord-293701-u4ntxo0y	255	67	skewing	skew	VBG
cord-293701-u4ntxo0y	255	68	macrophage	macrophage	NN
cord-293701-u4ntxo0y	255	69	responses	response	NNS
cord-293701-u4ntxo0y	255	70	during	during	IN
cord-293701-u4ntxo0y	255	71	acute	acute	JJ
cord-293701-u4ntxo0y	255	72	SARS	SARS	NNP
cord-293701-u4ntxo0y	255	73	-	-	HYPH
cord-293701-u4ntxo0y	255	74	CoV	CoV	NNP
cord-293701-u4ntxo0y	255	75	infection	infection	NN
cord-293701-u4ntxo0y	255	76	Early	early	JJ
cord-293701-u4ntxo0y	255	77	death	death	NN
cord-293701-u4ntxo0y	255	78	after	after	IN
cord-293701-u4ntxo0y	255	79	feline	feline	JJ
cord-293701-u4ntxo0y	255	80	infectious	infectious	JJ
cord-293701-u4ntxo0y	255	81	peritonitis	peritonitis	NN
cord-293701-u4ntxo0y	255	82	virus	virus	NN
cord-293701-u4ntxo0y	255	83	challenge	challenge	NN
cord-293701-u4ntxo0y	255	84	due	due	JJ
cord-293701-u4ntxo0y	255	85	to	to	IN
cord-293701-u4ntxo0y	255	86	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	255	87	vaccinia	vaccinia	NN
cord-293701-u4ntxo0y	255	88	virus	virus	NN
cord-293701-u4ntxo0y	255	89	immunization	immunization	NN
cord-293701-u4ntxo0y	255	90	Antibody	Antibody	NNP
cord-293701-u4ntxo0y	255	91	-	-	HYPH
cord-293701-u4ntxo0y	255	92	mediated	mediate	VBN
cord-293701-u4ntxo0y	255	93	enhancement	enhancement	NN
cord-293701-u4ntxo0y	255	94	of	of	IN
cord-293701-u4ntxo0y	255	95	disease	disease	NN
cord-293701-u4ntxo0y	255	96	in	in	IN
cord-293701-u4ntxo0y	255	97	feline	feline	JJ
cord-293701-u4ntxo0y	255	98	infectious	infectious	JJ
cord-293701-u4ntxo0y	255	99	peritonitis	peritonitis	NN
cord-293701-u4ntxo0y	255	100	:	:	:
cord-293701-u4ntxo0y	255	101	comparisons	comparison	NNS
cord-293701-u4ntxo0y	255	102	with	with	IN
cord-293701-u4ntxo0y	255	103	dengue	dengue	NN
cord-293701-u4ntxo0y	255	104	hemorrhagic	hemorrhagic	JJ
cord-293701-u4ntxo0y	255	105	fever	fever	NN
cord-293701-u4ntxo0y	255	106	Respiratory	respiratory	JJ
cord-293701-u4ntxo0y	255	107	synctial	synctial	JJ
cord-293701-u4ntxo0y	255	108	virus	virus	NN
cord-293701-u4ntxo0y	255	109	infection	infection	NN
cord-293701-u4ntxo0y	255	110	in	in	IN
cord-293701-u4ntxo0y	255	111	BALB	BALB	NNP
cord-293701-u4ntxo0y	255	112	/	/	SYM
cord-293701-u4ntxo0y	255	113	c	c	NN
cord-293701-u4ntxo0y	255	114	mice	mouse	NNS
cord-293701-u4ntxo0y	255	115	previously	previously	RB
cord-293701-u4ntxo0y	255	116	immunized	immunize	VBN
cord-293701-u4ntxo0y	255	117	with	with	IN
cord-293701-u4ntxo0y	255	118	formalininactivated	formalininactivated	JJ
cord-293701-u4ntxo0y	255	119	virus	virus	NN
cord-293701-u4ntxo0y	255	120	induces	induce	VBZ
cord-293701-u4ntxo0y	255	121	enhanced	enhance	VBN
cord-293701-u4ntxo0y	255	122	pulmonary	pulmonary	JJ
cord-293701-u4ntxo0y	255	123	inflammatory	inflammatory	JJ
cord-293701-u4ntxo0y	255	124	response	response	NN
cord-293701-u4ntxo0y	255	125	with	with	IN
cord-293701-u4ntxo0y	255	126	a	a	DT
cord-293701-u4ntxo0y	255	127	predominant	predominant	JJ
cord-293701-u4ntxo0y	255	128	Th2-like	th2-like	JJ
cord-293701-u4ntxo0y	255	129	cytokine	cytokine	NN
cord-293701-u4ntxo0y	255	130	pattern	pattern	NN
cord-293701-u4ntxo0y	255	131	Another	another	DT
cord-293701-u4ntxo0y	255	132	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	255	133	,	,	,
cord-293701-u4ntxo0y	255	134	another	another	DT
cord-293701-u4ntxo0y	255	135	epidemic	epidemic	NN
cord-293701-u4ntxo0y	255	136	,	,	,
cord-293701-u4ntxo0y	255	137	another	another	DT
cord-293701-u4ntxo0y	255	138	warning	warn	VBG
cord-293701-u4ntxo0y	255	139	Smallpox	smallpox	NN
cord-293701-u4ntxo0y	255	140	and	and	CC
cord-293701-u4ntxo0y	255	141	smallpox	smallpox	NN
cord-293701-u4ntxo0y	255	142	vaccination	vaccination	NN
cord-293701-u4ntxo0y	255	143	policy	policy	NN
cord-293701-u4ntxo0y	255	144	Effective	effective	JJ
cord-293701-u4ntxo0y	255	145	poliomyelitis	poliomyelitis	NN
cord-293701-u4ntxo0y	256	1	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	256	2	Respiratory	respiratory	JJ
cord-293701-u4ntxo0y	256	3	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	256	4	virus	virus	NN
cord-293701-u4ntxo0y	256	5	disease	disease	NN
cord-293701-u4ntxo0y	256	6	in	in	IN
cord-293701-u4ntxo0y	256	7	infants	infant	NNS
cord-293701-u4ntxo0y	256	8	despite	despite	IN
cord-293701-u4ntxo0y	256	9	prior	prior	JJ
cord-293701-u4ntxo0y	256	10	administration	administration	NN
cord-293701-u4ntxo0y	256	11	of	of	IN
cord-293701-u4ntxo0y	256	12	antigenic	antigenic	JJ
cord-293701-u4ntxo0y	256	13	inactivated	inactivated	JJ
cord-293701-u4ntxo0y	256	14	vaccine	vaccine	NN
cord-293701-u4ntxo0y	256	15	Dissociation	Dissociation	NNP
cord-293701-u4ntxo0y	256	16	between	between	IN
cord-293701-u4ntxo0y	256	17	serum	serum	NN
cord-293701-u4ntxo0y	256	18	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	256	19	and	and	CC
cord-293701-u4ntxo0y	256	20	glycoprotein	glycoprotein	NN
cord-293701-u4ntxo0y	256	21	antibody	antibody	NN
cord-293701-u4ntxo0y	256	22	responses	response	NNS
cord-293701-u4ntxo0y	256	23	of	of	IN
cord-293701-u4ntxo0y	256	24	infants	infant	NNS
cord-293701-u4ntxo0y	256	25	and	and	CC
cord-293701-u4ntxo0y	256	26	children	child	NNS
cord-293701-u4ntxo0y	256	27	who	who	WP
cord-293701-u4ntxo0y	256	28	received	receive	VBD
cord-293701-u4ntxo0y	256	29	inactivated	inactivated	JJ
cord-293701-u4ntxo0y	256	30	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	256	31	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	256	32	virus	virus	NN
cord-293701-u4ntxo0y	256	33	vaccine	vaccine	NN
cord-293701-u4ntxo0y	256	34	Cell	cell	NN
cord-293701-u4ntxo0y	256	35	-	-	HYPH
cord-293701-u4ntxo0y	256	36	mediated	mediate	VBN
cord-293701-u4ntxo0y	256	37	immunity	immunity	NN
cord-293701-u4ntxo0y	256	38	to	to	IN
cord-293701-u4ntxo0y	256	39	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	256	40	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	256	41	virus	virus	NN
cord-293701-u4ntxo0y	256	42	induced	induce	VBN
cord-293701-u4ntxo0y	256	43	by	by	IN
cord-293701-u4ntxo0y	256	44	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	256	45	vaccine	vaccine	NN
cord-293701-u4ntxo0y	256	46	or	or	CC
cord-293701-u4ntxo0y	256	47	by	by	IN
cord-293701-u4ntxo0y	256	48	infection	infection	NN
cord-293701-u4ntxo0y	256	49	Pulmonary	pulmonary	JJ
cord-293701-u4ntxo0y	256	50	histopathology	histopathology	NN
cord-293701-u4ntxo0y	256	51	induced	induce	VBN
cord-293701-u4ntxo0y	256	52	by	by	IN
cord-293701-u4ntxo0y	256	53	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	256	54	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	256	55	virus	virus	NN
cord-293701-u4ntxo0y	256	56	(	(	-LRB-
cord-293701-u4ntxo0y	256	57	RSV	RSV	NNP
cord-293701-u4ntxo0y	256	58	)	)	-RRB-
cord-293701-u4ntxo0y	256	59	challenge	challenge	NN
cord-293701-u4ntxo0y	256	60	of	of	IN
cord-293701-u4ntxo0y	256	61	formalin	formalin	NN
cord-293701-u4ntxo0y	256	62	-	-	HYPH
cord-293701-u4ntxo0y	256	63	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	256	64	RSV	rsv	NN
cord-293701-u4ntxo0y	256	65	-	-	HYPH
cord-293701-u4ntxo0y	256	66	immunized	immunize	VBN
cord-293701-u4ntxo0y	256	67	BALB	BALB	NNP
cord-293701-u4ntxo0y	256	68	/	/	SYM
cord-293701-u4ntxo0y	256	69	c	c	NN
cord-293701-u4ntxo0y	256	70	mice	mouse	NNS
cord-293701-u4ntxo0y	256	71	is	be	VBZ
cord-293701-u4ntxo0y	256	72	abrogated	abrogate	VBN
cord-293701-u4ntxo0y	256	73	by	by	IN
cord-293701-u4ntxo0y	256	74	depletion	depletion	NN
cord-293701-u4ntxo0y	256	75	of	of	IN
cord-293701-u4ntxo0y	256	76	CD4	CD4	NNP
cord-293701-u4ntxo0y	256	77	+	+	CC
cord-293701-u4ntxo0y	256	78	T	t	NN
cord-293701-u4ntxo0y	256	79	cells	cell	NNS
cord-293701-u4ntxo0y	257	1	Enhanced	enhanced	JJ
cord-293701-u4ntxo0y	257	2	pulmonary	pulmonary	JJ
cord-293701-u4ntxo0y	257	3	histopathology	histopathology	NN
cord-293701-u4ntxo0y	257	4	induced	induce	VBN
cord-293701-u4ntxo0y	257	5	by	by	IN
cord-293701-u4ntxo0y	257	6	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	257	7	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	257	8	virus	virus	NN
cord-293701-u4ntxo0y	257	9	(	(	-LRB-
cord-293701-u4ntxo0y	257	10	RSV	RSV	NNP
cord-293701-u4ntxo0y	257	11	)	)	-RRB-
cord-293701-u4ntxo0y	257	12	challenge	challenge	NN
cord-293701-u4ntxo0y	257	13	of	of	IN
cord-293701-u4ntxo0y	257	14	formalin	formalin	NN
cord-293701-u4ntxo0y	257	15	-	-	HYPH
cord-293701-u4ntxo0y	257	16	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	257	17	RSV	rsv	NN
cord-293701-u4ntxo0y	257	18	-	-	HYPH
cord-293701-u4ntxo0y	257	19	immunized	immunize	VBN
cord-293701-u4ntxo0y	257	20	BALB	BALB	NNP
cord-293701-u4ntxo0y	257	21	/	/	SYM
cord-293701-u4ntxo0y	257	22	c	c	NN
cord-293701-u4ntxo0y	257	23	mice	mouse	NNS
cord-293701-u4ntxo0y	257	24	is	be	VBZ
cord-293701-u4ntxo0y	257	25	abrogated	abrogate	VBN
cord-293701-u4ntxo0y	257	26	by	by	IN
cord-293701-u4ntxo0y	257	27	depletion	depletion	NN
cord-293701-u4ntxo0y	257	28	of	of	IN
cord-293701-u4ntxo0y	257	29	interleukin-4	interleukin-4	NNP
cord-293701-u4ntxo0y	257	30	(	(	-LRB-
cord-293701-u4ntxo0y	257	31	IL-4	IL-4	NNP
cord-293701-u4ntxo0y	257	32	)	)	-RRB-
cord-293701-u4ntxo0y	257	33	and	and	CC
cord-293701-u4ntxo0y	257	34	IL-10	IL-10	NNP
cord-293701-u4ntxo0y	257	35	Virus	virus	NN
cord-293701-u4ntxo0y	257	36	-	-	HYPH
cord-293701-u4ntxo0y	257	37	specific	specific	JJ
cord-293701-u4ntxo0y	257	38	CD8	CD8	NNP
cord-293701-u4ntxo0y	257	39	+	+	CC
cord-293701-u4ntxo0y	257	40	T	t	NN
cord-293701-u4ntxo0y	257	41	lymphocytes	lymphocyte	NNS
cord-293701-u4ntxo0y	257	42	downregulate	downregulate	VBP
cord-293701-u4ntxo0y	257	43	T	T	NNP
cord-293701-u4ntxo0y	257	44	helper	helper	NN
cord-293701-u4ntxo0y	257	45	cell	cell	NN
cord-293701-u4ntxo0y	257	46	type	type	NN
cord-293701-u4ntxo0y	257	47	2	2	CD
cord-293701-u4ntxo0y	257	48	cytokine	cytokine	NN
cord-293701-u4ntxo0y	257	49	secretion	secretion	NN
cord-293701-u4ntxo0y	257	50	and	and	CC
cord-293701-u4ntxo0y	257	51	pulmonary	pulmonary	JJ
cord-293701-u4ntxo0y	257	52	eosinophilia	eosinophilia	NN
cord-293701-u4ntxo0y	257	53	during	during	IN
cord-293701-u4ntxo0y	257	54	experimental	experimental	JJ
cord-293701-u4ntxo0y	257	55	murine	murine	JJ
cord-293701-u4ntxo0y	257	56	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	257	57	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	257	58	virus	virus	NN
cord-293701-u4ntxo0y	257	59	infection	infection	NN
cord-293701-u4ntxo0y	258	1	Cellular	cellular	JJ
cord-293701-u4ntxo0y	258	2	immune	immune	NN
cord-293701-u4ntxo0y	258	3	correlates	correlate	VBZ
cord-293701-u4ntxo0y	258	4	preventing	prevent	VBG
cord-293701-u4ntxo0y	258	5	disease	disease	NN
cord-293701-u4ntxo0y	258	6	against	against	IN
cord-293701-u4ntxo0y	258	7	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	258	8	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	258	9	virus	virus	NN
cord-293701-u4ntxo0y	258	10	by	by	IN
cord-293701-u4ntxo0y	258	11	vaccination	vaccination	NN
cord-293701-u4ntxo0y	258	12	with	with	IN
cord-293701-u4ntxo0y	258	13	virus	virus	NN
cord-293701-u4ntxo0y	258	14	-	-	HYPH
cord-293701-u4ntxo0y	258	15	like	like	JJ
cord-293701-u4ntxo0y	258	16	nanoparticles	nanoparticle	NNS
cord-293701-u4ntxo0y	258	17	carrying	carry	VBG
cord-293701-u4ntxo0y	258	18	fusion	fusion	NN
cord-293701-u4ntxo0y	258	19	proteins	protein	NNS
cord-293701-u4ntxo0y	259	1	A	a	DT
cord-293701-u4ntxo0y	259	2	potential	potential	JJ
cord-293701-u4ntxo0y	259	3	molecular	molecular	JJ
cord-293701-u4ntxo0y	259	4	mechanism	mechanism	NN
cord-293701-u4ntxo0y	259	5	for	for	IN
cord-293701-u4ntxo0y	259	6	hypersensitivity	hypersensitivity	NN
cord-293701-u4ntxo0y	259	7	caused	cause	VBN
cord-293701-u4ntxo0y	259	8	by	by	IN
cord-293701-u4ntxo0y	259	9	formalin	formalin	NN
cord-293701-u4ntxo0y	259	10	-	-	HYPH
cord-293701-u4ntxo0y	259	11	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	259	12	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	259	13	Enhanced	enhance	VBN
cord-293701-u4ntxo0y	259	14	pulmonary	pulmonary	JJ
cord-293701-u4ntxo0y	259	15	histopathology	histopathology	NN
cord-293701-u4ntxo0y	259	16	is	be	VBZ
cord-293701-u4ntxo0y	259	17	observed	observe	VBN
cord-293701-u4ntxo0y	259	18	in	in	IN
cord-293701-u4ntxo0y	259	19	cotton	cotton	NN
cord-293701-u4ntxo0y	259	20	rats	rat	NNS
cord-293701-u4ntxo0y	259	21	immunized	immunize	VBN
cord-293701-u4ntxo0y	259	22	with	with	IN
cord-293701-u4ntxo0y	259	23	formalin	formalin	NN
cord-293701-u4ntxo0y	259	24	-	-	HYPH
cord-293701-u4ntxo0y	259	25	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	259	26	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	259	27	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	259	28	virus	virus	NN
cord-293701-u4ntxo0y	259	29	(	(	-LRB-
cord-293701-u4ntxo0y	259	30	RSV	RSV	NNP
cord-293701-u4ntxo0y	259	31	)	)	-RRB-
cord-293701-u4ntxo0y	259	32	or	or	CC
cord-293701-u4ntxo0y	259	33	purified	purify	VBN
cord-293701-u4ntxo0y	259	34	F	F	NNP
cord-293701-u4ntxo0y	259	35	glycoprotein	glycoprotein	NN
cord-293701-u4ntxo0y	259	36	and	and	CC
cord-293701-u4ntxo0y	259	37	challenged	challenge	VBN
cord-293701-u4ntxo0y	259	38	with	with	IN
cord-293701-u4ntxo0y	259	39	RSV	RSV	NNP
cord-293701-u4ntxo0y	259	40	3	3	CD
cord-293701-u4ntxo0y	259	41	-	-	SYM
cord-293701-u4ntxo0y	259	42	6	6	CD
cord-293701-u4ntxo0y	259	43	months	month	NNS
cord-293701-u4ntxo0y	259	44	after	after	IN
cord-293701-u4ntxo0y	259	45	immunization	immunization	NN
cord-293701-u4ntxo0y	259	46	Generation	generation	NN
cord-293701-u4ntxo0y	259	47	of	of	IN
cord-293701-u4ntxo0y	259	48	atypical	atypical	JJ
cord-293701-u4ntxo0y	259	49	pulmonary	pulmonary	JJ
cord-293701-u4ntxo0y	259	50	inflammatory	inflammatory	JJ
cord-293701-u4ntxo0y	259	51	responses	response	NNS
cord-293701-u4ntxo0y	259	52	in	in	IN
cord-293701-u4ntxo0y	259	53	BALB	BALB	NNP
cord-293701-u4ntxo0y	259	54	/	/	SYM
cord-293701-u4ntxo0y	259	55	c	c	NN
cord-293701-u4ntxo0y	259	56	mice	mouse	NNS
cord-293701-u4ntxo0y	259	57	after	after	IN
cord-293701-u4ntxo0y	259	58	immunization	immunization	NN
cord-293701-u4ntxo0y	259	59	with	with	IN
cord-293701-u4ntxo0y	259	60	the	the	DT
cord-293701-u4ntxo0y	259	61	native	native	JJ
cord-293701-u4ntxo0y	259	62	attachment	attachment	NN
cord-293701-u4ntxo0y	259	63	(	(	-LRB-
cord-293701-u4ntxo0y	259	64	G	g	NN
cord-293701-u4ntxo0y	259	65	)	)	-RRB-
cord-293701-u4ntxo0y	259	66	glycoprotein	glycoprotein	NN
cord-293701-u4ntxo0y	259	67	of	of	IN
cord-293701-u4ntxo0y	259	68	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	259	69	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	259	70	virus	virus	NN
cord-293701-u4ntxo0y	259	71	Priming	prime	VBG
cord-293701-u4ntxo0y	259	72	immunization	immunization	NN
cord-293701-u4ntxo0y	259	73	determines	determine	VBZ
cord-293701-u4ntxo0y	259	74	T	T	NNP
cord-293701-u4ntxo0y	259	75	helper	helper	NN
cord-293701-u4ntxo0y	259	76	cytokine	cytokine	NN
cord-293701-u4ntxo0y	259	77	mRNA	mrna	NN
cord-293701-u4ntxo0y	259	78	expression	expression	NN
cord-293701-u4ntxo0y	259	79	patterns	pattern	NNS
cord-293701-u4ntxo0y	259	80	in	in	IN
cord-293701-u4ntxo0y	259	81	lungs	lung	NNS
cord-293701-u4ntxo0y	259	82	of	of	IN
cord-293701-u4ntxo0y	259	83	mice	mouse	NNS
cord-293701-u4ntxo0y	259	84	challenged	challenge	VBN
cord-293701-u4ntxo0y	259	85	with	with	IN
cord-293701-u4ntxo0y	259	86	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	259	87	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	259	88	virus	virus	NN
cord-293701-u4ntxo0y	259	89	Live	live	RB
cord-293701-u4ntxo0y	259	90	-	-	HYPH
cord-293701-u4ntxo0y	259	91	attenuated	attenuated	JJ
cord-293701-u4ntxo0y	259	92	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	259	93	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	259	94	virus	virus	NN
cord-293701-u4ntxo0y	259	95	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	259	96	The	the	DT
cord-293701-u4ntxo0y	259	97	absence	absence	NN
cord-293701-u4ntxo0y	259	98	of	of	IN
cord-293701-u4ntxo0y	259	99	enhanced	enhance	VBN
cord-293701-u4ntxo0y	259	100	disease	disease	NN
cord-293701-u4ntxo0y	259	101	with	with	IN
cord-293701-u4ntxo0y	259	102	wild	wild	JJ
cord-293701-u4ntxo0y	259	103	type	type	NN
cord-293701-u4ntxo0y	259	104	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	259	105	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	259	106	virus	virus	NN
cord-293701-u4ntxo0y	259	107	infection	infection	NN
cord-293701-u4ntxo0y	259	108	occurring	occur	VBG
cord-293701-u4ntxo0y	259	109	after	after	IN
cord-293701-u4ntxo0y	259	110	receipt	receipt	NN
cord-293701-u4ntxo0y	259	111	of	of	IN
cord-293701-u4ntxo0y	259	112	live	live	JJ
cord-293701-u4ntxo0y	259	113	,	,	,
cord-293701-u4ntxo0y	259	114	attenuated	attenuated	JJ
cord-293701-u4ntxo0y	259	115	,	,	,
cord-293701-u4ntxo0y	259	116	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	259	117	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	259	118	virus	virus	NN
cord-293701-u4ntxo0y	259	119	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	259	120	Progress	Progress	NNP
cord-293701-u4ntxo0y	259	121	in	in	IN
cord-293701-u4ntxo0y	259	122	understanding	understanding	NN
cord-293701-u4ntxo0y	259	123	and	and	CC
cord-293701-u4ntxo0y	259	124	controlling	control	VBG
cord-293701-u4ntxo0y	259	125	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	259	126	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	259	127	virus	virus	NN
cord-293701-u4ntxo0y	259	128	:	:	:
cord-293701-u4ntxo0y	259	129	still	still	RB
cord-293701-u4ntxo0y	259	130	crazy	crazy	JJ
cord-293701-u4ntxo0y	259	131	after	after	RB
cord-293701-u4ntxo0y	259	132	all	all	PDT
cord-293701-u4ntxo0y	259	133	these	these	DT
cord-293701-u4ntxo0y	259	134	years	year	NNS
cord-293701-u4ntxo0y	259	135	Prefusion	Prefusion	NNP
cord-293701-u4ntxo0y	259	136	F	F	NNP
cord-293701-u4ntxo0y	259	137	-	-	HYPH
cord-293701-u4ntxo0y	259	138	specific	specific	JJ
cord-293701-u4ntxo0y	259	139	antibodies	antibody	NNS
cord-293701-u4ntxo0y	259	140	determine	determine	VBP
cord-293701-u4ntxo0y	259	141	the	the	DT
cord-293701-u4ntxo0y	259	142	magnitude	magnitude	NN
cord-293701-u4ntxo0y	259	143	of	of	IN
cord-293701-u4ntxo0y	259	144	RSV	RSV	NNP
cord-293701-u4ntxo0y	259	145	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	259	146	activity	activity	NN
cord-293701-u4ntxo0y	259	147	in	in	IN
cord-293701-u4ntxo0y	259	148	human	human	JJ
cord-293701-u4ntxo0y	259	149	sera	sera	NNP
cord-293701-u4ntxo0y	259	150	Neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	259	151	antibodies	antibody	NNS
cord-293701-u4ntxo0y	259	152	against	against	IN
cord-293701-u4ntxo0y	259	153	the	the	DT
cord-293701-u4ntxo0y	259	154	preactive	preactive	JJ
cord-293701-u4ntxo0y	259	155	form	form	NN
cord-293701-u4ntxo0y	259	156	of	of	IN
cord-293701-u4ntxo0y	259	157	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	259	158	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	259	159	virus	virus	NN
cord-293701-u4ntxo0y	259	160	fusion	fusion	NN
cord-293701-u4ntxo0y	259	161	protein	protein	NN
cord-293701-u4ntxo0y	259	162	offer	offer	VBP
cord-293701-u4ntxo0y	259	163	unique	unique	JJ
cord-293701-u4ntxo0y	259	164	possibilities	possibility	NNS
cord-293701-u4ntxo0y	259	165	for	for	IN
cord-293701-u4ntxo0y	259	166	clinical	clinical	JJ
cord-293701-u4ntxo0y	259	167	intervention	intervention	NN
cord-293701-u4ntxo0y	259	168	Conformational	Conformational	NNP
cord-293701-u4ntxo0y	259	169	flexibility	flexibility	NN
cord-293701-u4ntxo0y	259	170	in	in	IN
cord-293701-u4ntxo0y	259	171	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	259	172	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	259	173	virus	virus	NN
cord-293701-u4ntxo0y	259	174	G	g	NN
cord-293701-u4ntxo0y	259	175	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	259	176	epitopes	epitope	NNS
cord-293701-u4ntxo0y	259	177	Epitope	epitope	NN
cord-293701-u4ntxo0y	259	178	-	-	HYPH
cord-293701-u4ntxo0y	259	179	specific	specific	JJ
cord-293701-u4ntxo0y	259	180	serological	serological	JJ
cord-293701-u4ntxo0y	259	181	assays	assay	NNS
cord-293701-u4ntxo0y	259	182	for	for	IN
cord-293701-u4ntxo0y	259	183	RSV	RSV	NNP
cord-293701-u4ntxo0y	259	184	:	:	:
cord-293701-u4ntxo0y	260	1	conformation	conformation	NN
cord-293701-u4ntxo0y	260	2	matters	matter	VBZ
cord-293701-u4ntxo0y	260	3	Immunization	Immunization	NNP
cord-293701-u4ntxo0y	260	4	with	with	IN
cord-293701-u4ntxo0y	260	5	low	low	JJ
cord-293701-u4ntxo0y	260	6	doses	dose	NNS
cord-293701-u4ntxo0y	260	7	of	of	IN
cord-293701-u4ntxo0y	260	8	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	260	9	postfusion	postfusion	NN
cord-293701-u4ntxo0y	260	10	or	or	CC
cord-293701-u4ntxo0y	260	11	prefusion	prefusion	NN
cord-293701-u4ntxo0y	260	12	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	260	13	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	260	14	virus	virus	NN
cord-293701-u4ntxo0y	260	15	f	f	CD
cord-293701-u4ntxo0y	260	16	primes	prime	NNS
cord-293701-u4ntxo0y	260	17	for	for	IN
cord-293701-u4ntxo0y	260	18	vaccine	vaccine	NN
cord-293701-u4ntxo0y	260	19	-	-	HYPH
cord-293701-u4ntxo0y	260	20	enhanced	enhance	VBN
cord-293701-u4ntxo0y	260	21	disease	disease	NN
cord-293701-u4ntxo0y	260	22	in	in	IN
cord-293701-u4ntxo0y	260	23	the	the	DT
cord-293701-u4ntxo0y	260	24	cotton	cotton	NN
cord-293701-u4ntxo0y	260	25	rat	rat	NN
cord-293701-u4ntxo0y	260	26	model	model	NN
cord-293701-u4ntxo0y	261	1	independently	independently	RB
cord-293701-u4ntxo0y	261	2	of	of	IN
cord-293701-u4ntxo0y	261	3	the	the	DT
cord-293701-u4ntxo0y	261	4	presence	presence	NN
cord-293701-u4ntxo0y	261	5	of	of	IN
cord-293701-u4ntxo0y	261	6	a	a	DT
cord-293701-u4ntxo0y	261	7	Th1-biasing	Th1-biasing	NNP
cord-293701-u4ntxo0y	261	8	C5	C5	NNP
cord-293701-u4ntxo0y	261	9	modulates	modulate	VBZ
cord-293701-u4ntxo0y	261	10	airway	airway	NNP
cord-293701-u4ntxo0y	261	11	hyperreactivity	hyperreactivity	NN
cord-293701-u4ntxo0y	261	12	and	and	CC
cord-293701-u4ntxo0y	261	13	pulmonary	pulmonary	JJ
cord-293701-u4ntxo0y	261	14	eosinophilia	eosinophilia	NN
cord-293701-u4ntxo0y	261	15	during	during	IN
cord-293701-u4ntxo0y	261	16	enhanced	enhanced	JJ
cord-293701-u4ntxo0y	261	17	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	261	18	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	261	19	virus	virus	NN
cord-293701-u4ntxo0y	261	20	disease	disease	NN
cord-293701-u4ntxo0y	261	21	by	by	IN
cord-293701-u4ntxo0y	261	22	decreasing	decrease	VBG
cord-293701-u4ntxo0y	261	23	C3a	C3a	NNP
cord-293701-u4ntxo0y	261	24	receptor	receptor	NN
cord-293701-u4ntxo0y	261	25	expression	expression	NN
cord-293701-u4ntxo0y	261	26	Adenovector	Adenovector	NNP
cord-293701-u4ntxo0y	261	27	26	26	CD
cord-293701-u4ntxo0y	262	1	encoded	encode	VBN
cord-293701-u4ntxo0y	262	2	prefusion	prefusion	NN
cord-293701-u4ntxo0y	262	3	conformation	conformation	NN
cord-293701-u4ntxo0y	262	4	stabilized	stabilize	VBD
cord-293701-u4ntxo0y	262	5	RSV	RSV	NNP
cord-293701-u4ntxo0y	262	6	-	-	HYPH
cord-293701-u4ntxo0y	262	7	F	F	NNP
cord-293701-u4ntxo0y	262	8	protein	protein	NN
cord-293701-u4ntxo0y	262	9	induces	induce	VBZ
cord-293701-u4ntxo0y	262	10	long	long	RB
cord-293701-u4ntxo0y	262	11	-	-	HYPH
cord-293701-u4ntxo0y	262	12	lasting	last	VBG
cord-293701-u4ntxo0y	262	13	Th1-biased	th1-biased	JJ
cord-293701-u4ntxo0y	262	14	immunity	immunity	NN
cord-293701-u4ntxo0y	262	15	in	in	IN
cord-293701-u4ntxo0y	262	16	neonatal	neonatal	JJ
cord-293701-u4ntxo0y	262	17	mice	mouse	NNS
cord-293701-u4ntxo0y	262	18	Phase	phase	NN
cord-293701-u4ntxo0y	262	19	1	1	CD
cord-293701-u4ntxo0y	262	20	safety	safety	NN
cord-293701-u4ntxo0y	262	21	and	and	CC
cord-293701-u4ntxo0y	262	22	immunogenicity	immunogenicity	NN
cord-293701-u4ntxo0y	262	23	study	study	NN
cord-293701-u4ntxo0y	262	24	of	of	IN
cord-293701-u4ntxo0y	262	25	a	a	DT
cord-293701-u4ntxo0y	262	26	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	262	27	syncytial	syncytial	JJ
cord-293701-u4ntxo0y	262	28	virus	virus	NN
cord-293701-u4ntxo0y	262	29	vaccine	vaccine	NN
cord-293701-u4ntxo0y	262	30	with	with	IN
cord-293701-u4ntxo0y	262	31	an	an	DT
cord-293701-u4ntxo0y	262	32	adenovirus	adenovirus	NN
cord-293701-u4ntxo0y	262	33	26	26	CD
cord-293701-u4ntxo0y	262	34	vector	vector	NN
cord-293701-u4ntxo0y	262	35	encoding	encoding	NN
cord-293701-u4ntxo0y	262	36	prefusion	prefusion	NNP
cord-293701-u4ntxo0y	262	37	F	F	NNP
cord-293701-u4ntxo0y	262	38	(	(	-LRB-
cord-293701-u4ntxo0y	262	39	Ad26.RSV.preF	Ad26.RSV.preF	NNP
cord-293701-u4ntxo0y	262	40	)	)	-RRB-
cord-293701-u4ntxo0y	262	41	in	in	IN
cord-293701-u4ntxo0y	262	42	adults	adult	NNS
cord-293701-u4ntxo0y	262	43	aged	age	VBN
cord-293701-u4ntxo0y	263	1	>	>	XX
cord-293701-u4ntxo0y	264	1	/=60	/=60	NNP
cord-293701-u4ntxo0y	264	2	years	year	NNS
cord-293701-u4ntxo0y	265	1	Contributions	contribution	NNS
cord-293701-u4ntxo0y	265	2	to	to	IN
cord-293701-u4ntxo0y	265	3	the	the	DT
cord-293701-u4ntxo0y	265	4	study	study	NN
cord-293701-u4ntxo0y	265	5	of	of	IN
cord-293701-u4ntxo0y	265	6	vaccination	vaccination	NN
cord-293701-u4ntxo0y	265	7	against	against	IN
cord-293701-u4ntxo0y	265	8	dengue	dengue	NN
cord-293701-u4ntxo0y	265	9	A	a	DT
cord-293701-u4ntxo0y	265	10	study	study	NN
cord-293701-u4ntxo0y	265	11	on	on	IN
cord-293701-u4ntxo0y	265	12	susceptibility	susceptibility	NN
cord-293701-u4ntxo0y	265	13	of	of	IN
cord-293701-u4ntxo0y	265	14	Indonesia	Indonesia	NNP
cord-293701-u4ntxo0y	265	15	colonies	colony	NNS
cord-293701-u4ntxo0y	265	16	of	of	IN
cord-293701-u4ntxo0y	265	17	Aedes	Aedes	NNP
cord-293701-u4ntxo0y	265	18	aegypti	aegypti	NN
cord-293701-u4ntxo0y	265	19	and	and	CC
cord-293701-u4ntxo0y	265	20	Aedes	Aedes	NNP
cord-293701-u4ntxo0y	265	21	albopictus	albopictus	NN
cord-293701-u4ntxo0y	265	22	mosquitoes	mosquito	NNS
cord-293701-u4ntxo0y	265	23	to	to	IN
cord-293701-u4ntxo0y	265	24	experimental	experimental	JJ
cord-293701-u4ntxo0y	265	25	infection	infection	NN
cord-293701-u4ntxo0y	265	26	with	with	IN
cord-293701-u4ntxo0y	265	27	dengue	dengue	NN
cord-293701-u4ntxo0y	265	28	type	type	NN
cord-293701-u4ntxo0y	265	29	3	3	CD
cord-293701-u4ntxo0y	265	30	and	and	CC
cord-293701-u4ntxo0y	265	31	chikungunya	chikungunya	NN
cord-293701-u4ntxo0y	265	32	viruses	virus	NNS
cord-293701-u4ntxo0y	266	1	The	the	DT
cord-293701-u4ntxo0y	266	2	human	human	JJ
cord-293701-u4ntxo0y	266	3	antibody	antibody	NN
cord-293701-u4ntxo0y	266	4	response	response	NN
cord-293701-u4ntxo0y	266	5	to	to	IN
cord-293701-u4ntxo0y	266	6	dengue	dengue	NN
cord-293701-u4ntxo0y	266	7	virus	virus	NN
cord-293701-u4ntxo0y	266	8	infection	infection	NN
cord-293701-u4ntxo0y	266	9	Clinical	clinical	JJ
cord-293701-u4ntxo0y	266	10	and	and	CC
cord-293701-u4ntxo0y	266	11	serologic	serologic	JJ
cord-293701-u4ntxo0y	266	12	response	response	NN
cord-293701-u4ntxo0y	266	13	of	of	IN
cord-293701-u4ntxo0y	266	14	man	man	NN
cord-293701-u4ntxo0y	266	15	to	to	IN
cord-293701-u4ntxo0y	266	16	immunization	immunization	NN
cord-293701-u4ntxo0y	266	17	with	with	IN
cord-293701-u4ntxo0y	266	18	attenuated	attenuated	JJ
cord-293701-u4ntxo0y	266	19	dengue	dengue	NN
cord-293701-u4ntxo0y	266	20	and	and	CC
cord-293701-u4ntxo0y	266	21	yellow	yellow	JJ
cord-293701-u4ntxo0y	266	22	fever	fever	NN
cord-293701-u4ntxo0y	266	23	viruses	virus	NNS
cord-293701-u4ntxo0y	266	24	Review	Review	NNP
cord-293701-u4ntxo0y	266	25	article	article	NN
cord-293701-u4ntxo0y	266	26	:	:	:
cord-293701-u4ntxo0y	267	1	research	research	NN
cord-293701-u4ntxo0y	267	2	on	on	IN
cord-293701-u4ntxo0y	267	3	dengue	dengue	NN
cord-293701-u4ntxo0y	267	4	during	during	IN
cord-293701-u4ntxo0y	267	5	World	World	NNP
cord-293701-u4ntxo0y	267	6	War	War	NNP
cord-293701-u4ntxo0y	267	7	II	II	NNP
cord-293701-u4ntxo0y	267	8	revisited	revisit	VBD
cord-293701-u4ntxo0y	267	9	Evidence	evidence	NN
cord-293701-u4ntxo0y	267	10	that	that	IN
cord-293701-u4ntxo0y	267	11	maternal	maternal	JJ
cord-293701-u4ntxo0y	267	12	dengue	dengue	NN
cord-293701-u4ntxo0y	267	13	antibodies	antibody	NNS
cord-293701-u4ntxo0y	267	14	are	be	VBP
cord-293701-u4ntxo0y	267	15	important	important	JJ
cord-293701-u4ntxo0y	267	16	in	in	IN
cord-293701-u4ntxo0y	267	17	the	the	DT
cord-293701-u4ntxo0y	267	18	development	development	NN
cord-293701-u4ntxo0y	267	19	of	of	IN
cord-293701-u4ntxo0y	267	20	dengue	dengue	NN
cord-293701-u4ntxo0y	267	21	hemorrhagic	hemorrhagic	JJ
cord-293701-u4ntxo0y	267	22	fever	fever	NN
cord-293701-u4ntxo0y	267	23	in	in	IN
cord-293701-u4ntxo0y	267	24	infants	infant	NNS
cord-293701-u4ntxo0y	267	25	Observations	observation	NNS
cord-293701-u4ntxo0y	267	26	related	relate	VBN
cord-293701-u4ntxo0y	267	27	to	to	IN
cord-293701-u4ntxo0y	267	28	pathogenesis	pathogenesis	NN
cord-293701-u4ntxo0y	267	29	of	of	IN
cord-293701-u4ntxo0y	267	30	dengue	dengue	NN
cord-293701-u4ntxo0y	267	31	hemorrhagic	hemorrhagic	JJ
cord-293701-u4ntxo0y	267	32	fever	fever	NN
cord-293701-u4ntxo0y	267	33	.	.	.
cord-293701-u4ntxo0y	268	1	IV	IV	NNP
cord-293701-u4ntxo0y	268	2	.	.	.
cord-293701-u4ntxo0y	269	1	Relation	relation	NN
cord-293701-u4ntxo0y	269	2	of	of	IN
cord-293701-u4ntxo0y	269	3	disease	disease	NN
cord-293701-u4ntxo0y	269	4	severity	severity	NN
cord-293701-u4ntxo0y	269	5	to	to	IN
cord-293701-u4ntxo0y	269	6	antibody	antibody	NN
cord-293701-u4ntxo0y	269	7	response	response	NN
cord-293701-u4ntxo0y	269	8	and	and	CC
cord-293701-u4ntxo0y	269	9	virus	virus	NN
cord-293701-u4ntxo0y	269	10	recovered	recover	VBD
cord-293701-u4ntxo0y	269	11	Antibody	antibody	NN
cord-293701-u4ntxo0y	269	12	-	-	HYPH
cord-293701-u4ntxo0y	269	13	dependent	dependent	JJ
cord-293701-u4ntxo0y	269	14	enhancement	enhancement	NN
cord-293701-u4ntxo0y	269	15	of	of	IN
cord-293701-u4ntxo0y	269	16	severe	severe	JJ
cord-293701-u4ntxo0y	269	17	dengue	dengue	NN
cord-293701-u4ntxo0y	269	18	disease	disease	NN
cord-293701-u4ntxo0y	269	19	in	in	IN
cord-293701-u4ntxo0y	269	20	humans	human	NNS
cord-293701-u4ntxo0y	269	21	Reconstruction	Reconstruction	NNP
cord-293701-u4ntxo0y	269	22	of	of	IN
cord-293701-u4ntxo0y	269	23	antibody	antibody	NN
cord-293701-u4ntxo0y	269	24	dynamics	dynamic	NNS
cord-293701-u4ntxo0y	269	25	and	and	CC
cord-293701-u4ntxo0y	269	26	infection	infection	NN
cord-293701-u4ntxo0y	269	27	histories	history	NNS
cord-293701-u4ntxo0y	269	28	to	to	TO
cord-293701-u4ntxo0y	269	29	evaluate	evaluate	VB
cord-293701-u4ntxo0y	269	30	dengue	dengue	NN
cord-293701-u4ntxo0y	269	31	risk	risk	NN
cord-293701-u4ntxo0y	269	32	Immunity	immunity	NN
cord-293701-u4ntxo0y	269	33	to	to	IN
cord-293701-u4ntxo0y	269	34	dengue	dengue	NN
cord-293701-u4ntxo0y	269	35	virus	virus	NN
cord-293701-u4ntxo0y	269	36	:	:	:
cord-293701-u4ntxo0y	269	37	a	a	DT
cord-293701-u4ntxo0y	269	38	tale	tale	NN
cord-293701-u4ntxo0y	269	39	of	of	IN
cord-293701-u4ntxo0y	269	40	original	original	JJ
cord-293701-u4ntxo0y	269	41	antigenic	antigenic	JJ
cord-293701-u4ntxo0y	269	42	sin	sin	NN
cord-293701-u4ntxo0y	269	43	and	and	CC
cord-293701-u4ntxo0y	269	44	tropical	tropical	JJ
cord-293701-u4ntxo0y	269	45	cytokine	cytokine	NN
cord-293701-u4ntxo0y	269	46	storms	storm	NNS
cord-293701-u4ntxo0y	269	47	Clinical	clinical	JJ
cord-293701-u4ntxo0y	269	48	efficacy	efficacy	NN
cord-293701-u4ntxo0y	269	49	and	and	CC
cord-293701-u4ntxo0y	269	50	safety	safety	NN
cord-293701-u4ntxo0y	269	51	of	of	IN
cord-293701-u4ntxo0y	269	52	a	a	DT
cord-293701-u4ntxo0y	269	53	novel	novel	JJ
cord-293701-u4ntxo0y	269	54	tetravalent	tetravalent	NN
cord-293701-u4ntxo0y	269	55	dengue	dengue	NN
cord-293701-u4ntxo0y	269	56	vaccine	vaccine	NN
cord-293701-u4ntxo0y	269	57	in	in	IN
cord-293701-u4ntxo0y	269	58	healthy	healthy	JJ
cord-293701-u4ntxo0y	269	59	children	child	NNS
cord-293701-u4ntxo0y	269	60	in	in	IN
cord-293701-u4ntxo0y	269	61	Asia	Asia	NNP
cord-293701-u4ntxo0y	269	62	:	:	:
cord-293701-u4ntxo0y	269	63	a	a	DT
cord-293701-u4ntxo0y	269	64	phase	phase	NN
cord-293701-u4ntxo0y	269	65	3	3	CD
cord-293701-u4ntxo0y	269	66	,	,	,
cord-293701-u4ntxo0y	269	67	randomised	randomised	JJ
cord-293701-u4ntxo0y	269	68	,	,	,
cord-293701-u4ntxo0y	269	69	observer	observer	NN
cord-293701-u4ntxo0y	269	70	-	-	HYPH
cord-293701-u4ntxo0y	269	71	masked	mask	VBN
cord-293701-u4ntxo0y	269	72	,	,	,
cord-293701-u4ntxo0y	269	73	placebo	placebo	NN
cord-293701-u4ntxo0y	269	74	-	-	HYPH
cord-293701-u4ntxo0y	269	75	controlled	control	VBN
cord-293701-u4ntxo0y	269	76	trial	trial	NN
cord-293701-u4ntxo0y	269	77	Effect	effect	NN
cord-293701-u4ntxo0y	269	78	of	of	IN
cord-293701-u4ntxo0y	269	79	dengue	dengue	NN
cord-293701-u4ntxo0y	269	80	serostatus	serostatus	NN
cord-293701-u4ntxo0y	269	81	on	on	IN
cord-293701-u4ntxo0y	269	82	dengue	dengue	NN
cord-293701-u4ntxo0y	269	83	vaccine	vaccine	NN
cord-293701-u4ntxo0y	269	84	safety	safety	NN
cord-293701-u4ntxo0y	269	85	and	and	CC
cord-293701-u4ntxo0y	269	86	efficacy	efficacy	NN
cord-293701-u4ntxo0y	270	1	On	on	IN
cord-293701-u4ntxo0y	270	2	the	the	DT
cord-293701-u4ntxo0y	270	3	origin	origin	NN
cord-293701-u4ntxo0y	270	4	and	and	CC
cord-293701-u4ntxo0y	270	5	continuing	continue	VBG
cord-293701-u4ntxo0y	270	6	evolution	evolution	NN
cord-293701-u4ntxo0y	270	7	of	of	IN
cord-293701-u4ntxo0y	270	8	SARS	SARS	NNP
cord-293701-u4ntxo0y	270	9	-	-	HYPH
cord-293701-u4ntxo0y	270	10	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	270	11	Discovery	Discovery	NNP
cord-293701-u4ntxo0y	270	12	and	and	CC
cord-293701-u4ntxo0y	270	13	genomic	genomic	JJ
cord-293701-u4ntxo0y	270	14	characterization	characterization	NN
cord-293701-u4ntxo0y	270	15	of	of	IN
cord-293701-u4ntxo0y	270	16	a	a	DT
cord-293701-u4ntxo0y	270	17	382-nucleotide	382-nucleotide	CD
cord-293701-u4ntxo0y	270	18	deletion	deletion	NN
cord-293701-u4ntxo0y	270	19	in	in	IN
cord-293701-u4ntxo0y	270	20	ORF7b	ORF7b	NNP
cord-293701-u4ntxo0y	270	21	and	and	CC
cord-293701-u4ntxo0y	270	22	ORF8	ORF8	NNP
cord-293701-u4ntxo0y	270	23	during	during	IN
cord-293701-u4ntxo0y	270	24	the	the	DT
cord-293701-u4ntxo0y	270	25	early	early	JJ
cord-293701-u4ntxo0y	270	26	evolution	evolution	NN
cord-293701-u4ntxo0y	270	27	of	of	IN
cord-293701-u4ntxo0y	270	28	SARS	SARS	NNP
cord-293701-u4ntxo0y	270	29	-	-	HYPH
cord-293701-u4ntxo0y	270	30	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	270	31	Tracking	tracking	NN
cord-293701-u4ntxo0y	270	32	changes	change	NNS
cord-293701-u4ntxo0y	270	33	in	in	IN
cord-293701-u4ntxo0y	270	34	SARS	SARS	NNP
cord-293701-u4ntxo0y	270	35	-	-	HYPH
cord-293701-u4ntxo0y	270	36	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	270	37	spike	spike	NN
cord-293701-u4ntxo0y	270	38	:	:	:
cord-293701-u4ntxo0y	270	39	evidence	evidence	NN
cord-293701-u4ntxo0y	270	40	that	that	IN
cord-293701-u4ntxo0y	270	41	D614	d614	CD
cord-293701-u4ntxo0y	270	42	G	g	NN
cord-293701-u4ntxo0y	270	43	increases	increase	VBZ
cord-293701-u4ntxo0y	270	44	infectivity	infectivity	NN
cord-293701-u4ntxo0y	270	45	of	of	IN
cord-293701-u4ntxo0y	270	46	the	the	DT
cord-293701-u4ntxo0y	270	47	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	270	48	virus	virus	NN
cord-293701-u4ntxo0y	270	49	Efficacy	Efficacy	NNP
cord-293701-u4ntxo0y	270	50	of	of	IN
cord-293701-u4ntxo0y	270	51	a	a	DT
cord-293701-u4ntxo0y	270	52	tetravalent	tetravalent	NN
cord-293701-u4ntxo0y	270	53	dengue	dengue	NN
cord-293701-u4ntxo0y	270	54	vaccine	vaccine	NN
cord-293701-u4ntxo0y	270	55	in	in	IN
cord-293701-u4ntxo0y	270	56	children	child	NNS
cord-293701-u4ntxo0y	270	57	in	in	IN
cord-293701-u4ntxo0y	270	58	Latin	Latin	NNP
cord-293701-u4ntxo0y	270	59	America	America	NNP
cord-293701-u4ntxo0y	270	60	Factors	Factors	NNP
cord-293701-u4ntxo0y	270	61	associated	associate	VBN
cord-293701-u4ntxo0y	270	62	with	with	IN
cord-293701-u4ntxo0y	270	63	hospital	hospital	NN
cord-293701-u4ntxo0y	270	64	admission	admission	NN
cord-293701-u4ntxo0y	270	65	and	and	CC
cord-293701-u4ntxo0y	270	66	critical	critical	JJ
cord-293701-u4ntxo0y	270	67	illness	illness	NN
cord-293701-u4ntxo0y	270	68	among	among	IN
cord-293701-u4ntxo0y	270	69	5279	5279	CD
cord-293701-u4ntxo0y	270	70	people	people	NNS
cord-293701-u4ntxo0y	270	71	with	with	IN
cord-293701-u4ntxo0y	270	72	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	270	73	disease	disease	NN
cord-293701-u4ntxo0y	271	1	A	a	DT
cord-293701-u4ntxo0y	271	2	pneumonia	pneumonia	NN
cord-293701-u4ntxo0y	271	3	outbreak	outbreak	NN
cord-293701-u4ntxo0y	271	4	associated	associate	VBN
cord-293701-u4ntxo0y	271	5	with	with	IN
cord-293701-u4ntxo0y	271	6	a	a	DT
cord-293701-u4ntxo0y	271	7	new	new	JJ
cord-293701-u4ntxo0y	271	8	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	271	9	of	of	IN
cord-293701-u4ntxo0y	271	10	probable	probable	JJ
cord-293701-u4ntxo0y	271	11	bat	bat	NN
cord-293701-u4ntxo0y	271	12	origin	origin	NN
cord-293701-u4ntxo0y	271	13	Structure	structure	NN
cord-293701-u4ntxo0y	271	14	,	,	,
cord-293701-u4ntxo0y	271	15	function	function	NN
cord-293701-u4ntxo0y	271	16	,	,	,
cord-293701-u4ntxo0y	271	17	and	and	CC
cord-293701-u4ntxo0y	271	18	antigenicity	antigenicity	NN
cord-293701-u4ntxo0y	271	19	of	of	IN
cord-293701-u4ntxo0y	271	20	the	the	DT
cord-293701-u4ntxo0y	271	21	SARS	SARS	NNP
cord-293701-u4ntxo0y	271	22	-	-	HYPH
cord-293701-u4ntxo0y	271	23	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	271	24	spike	spike	NN
cord-293701-u4ntxo0y	271	25	glycoprotein	glycoprotein	NN
cord-293701-u4ntxo0y	271	26	Effects	effect	NNS
cord-293701-u4ntxo0y	271	27	of	of	IN
cord-293701-u4ntxo0y	271	28	a	a	DT
cord-293701-u4ntxo0y	271	29	SARS	SARS	NNP
cord-293701-u4ntxo0y	271	30	-	-	HYPH
cord-293701-u4ntxo0y	271	31	associated	associate	VBN
cord-293701-u4ntxo0y	271	32	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	271	33	vaccine	vaccine	NN
cord-293701-u4ntxo0y	271	34	in	in	IN
cord-293701-u4ntxo0y	271	35	monkeys	monkey	NNS
cord-293701-u4ntxo0y	271	36	Adenovirus	Adenovirus	NNP
cord-293701-u4ntxo0y	271	37	-	-	HYPH
cord-293701-u4ntxo0y	271	38	based	base	VBN
cord-293701-u4ntxo0y	271	39	vaccine	vaccine	NN
cord-293701-u4ntxo0y	271	40	prevents	prevent	VBZ
cord-293701-u4ntxo0y	271	41	pneumonia	pneumonia	NN
cord-293701-u4ntxo0y	271	42	in	in	IN
cord-293701-u4ntxo0y	271	43	ferrets	ferret	NNS
cord-293701-u4ntxo0y	271	44	challenged	challenge	VBN
cord-293701-u4ntxo0y	271	45	with	with	IN
cord-293701-u4ntxo0y	271	46	the	the	DT
cord-293701-u4ntxo0y	271	47	SARS	SARS	NNP
cord-293701-u4ntxo0y	271	48	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	271	49	and	and	CC
cord-293701-u4ntxo0y	271	50	stimulates	stimulate	VBZ
cord-293701-u4ntxo0y	271	51	robust	robust	JJ
cord-293701-u4ntxo0y	271	52	immune	immune	JJ
cord-293701-u4ntxo0y	271	53	responses	response	NNS
cord-293701-u4ntxo0y	271	54	in	in	IN
cord-293701-u4ntxo0y	271	55	macaques	macaque	NNS
cord-293701-u4ntxo0y	271	56	Immunization	Immunization	NNP
cord-293701-u4ntxo0y	271	57	with	with	IN
cord-293701-u4ntxo0y	271	58	modified	modify	VBN
cord-293701-u4ntxo0y	271	59	vaccinia	vaccinia	NN
cord-293701-u4ntxo0y	271	60	virus	virus	NN
cord-293701-u4ntxo0y	271	61	Ankara	Ankara	NNP
cord-293701-u4ntxo0y	271	62	-	-	HYPH
cord-293701-u4ntxo0y	271	63	based	base	VBN
cord-293701-u4ntxo0y	271	64	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	271	65	vaccine	vaccine	NN
cord-293701-u4ntxo0y	271	66	against	against	IN
cord-293701-u4ntxo0y	271	67	severe	severe	JJ
cord-293701-u4ntxo0y	271	68	acute	acute	JJ
cord-293701-u4ntxo0y	271	69	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	271	70	syndrome	syndrome	NN
cord-293701-u4ntxo0y	271	71	is	be	VBZ
cord-293701-u4ntxo0y	271	72	associated	associate	VBN
cord-293701-u4ntxo0y	271	73	with	with	IN
cord-293701-u4ntxo0y	271	74	enhanced	enhance	VBN
cord-293701-u4ntxo0y	271	75	hepatitis	hepatitis	NN
cord-293701-u4ntxo0y	271	76	in	in	IN
cord-293701-u4ntxo0y	271	77	ferrets	ferret	NNS
cord-293701-u4ntxo0y	271	78	Evaluation	Evaluation	NNP
cord-293701-u4ntxo0y	271	79	of	of	IN
cord-293701-u4ntxo0y	271	80	modified	modify	VBN
cord-293701-u4ntxo0y	271	81	vaccinia	vaccinia	NN
cord-293701-u4ntxo0y	271	82	virus	virus	NN
cord-293701-u4ntxo0y	272	1	Ankara	Ankara	NNP
cord-293701-u4ntxo0y	272	2	based	base	VBN
cord-293701-u4ntxo0y	272	3	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	272	4	SARS	SARS	NNP
cord-293701-u4ntxo0y	272	5	vaccine	vaccine	NN
cord-293701-u4ntxo0y	272	6	in	in	IN
cord-293701-u4ntxo0y	272	7	ferrets	ferret	NNS
cord-293701-u4ntxo0y	273	1	A	a	DT
cord-293701-u4ntxo0y	273	2	double	double	RB
cord-293701-u4ntxo0y	273	3	-	-	HYPH
cord-293701-u4ntxo0y	273	4	inactivated	inactivated	JJ
cord-293701-u4ntxo0y	273	5	severe	severe	JJ
cord-293701-u4ntxo0y	273	6	acute	acute	JJ
cord-293701-u4ntxo0y	273	7	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	273	8	syndrome	syndrome	NN
cord-293701-u4ntxo0y	273	9	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	273	10	vaccine	vaccine	NN
cord-293701-u4ntxo0y	273	11	provides	provide	VBZ
cord-293701-u4ntxo0y	273	12	incomplete	incomplete	JJ
cord-293701-u4ntxo0y	273	13	protection	protection	NN
cord-293701-u4ntxo0y	273	14	in	in	IN
cord-293701-u4ntxo0y	273	15	mice	mouse	NNS
cord-293701-u4ntxo0y	273	16	and	and	CC
cord-293701-u4ntxo0y	273	17	induces	induce	VBZ
cord-293701-u4ntxo0y	273	18	increased	increase	VBN
cord-293701-u4ntxo0y	273	19	eosinophilic	eosinophilic	JJ
cord-293701-u4ntxo0y	273	20	proinflammatory	proinflammatory	JJ
cord-293701-u4ntxo0y	273	21	pulmonary	pulmonary	JJ
cord-293701-u4ntxo0y	273	22	response	response	NN
cord-293701-u4ntxo0y	273	23	upon	upon	IN
cord-293701-u4ntxo0y	273	24	challenge	challenge	NN
cord-293701-u4ntxo0y	274	1	Prior	prior	JJ
cord-293701-u4ntxo0y	274	2	immunization	immunization	NN
cord-293701-u4ntxo0y	274	3	with	with	IN
cord-293701-u4ntxo0y	274	4	severe	severe	JJ
cord-293701-u4ntxo0y	274	5	acute	acute	JJ
cord-293701-u4ntxo0y	274	6	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	274	7	syndrome	syndrome	NN
cord-293701-u4ntxo0y	274	8	(	(	-LRB-
cord-293701-u4ntxo0y	274	9	SARS)-associated	sars)-associated	CD
cord-293701-u4ntxo0y	274	10	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	274	11	(	(	-LRB-
cord-293701-u4ntxo0y	274	12	SARS	SARS	NNP
cord-293701-u4ntxo0y	274	13	-	-	HYPH
cord-293701-u4ntxo0y	274	14	CoV	CoV	NNP
cord-293701-u4ntxo0y	274	15	)	)	-RRB-
cord-293701-u4ntxo0y	275	1	nucleocapsid	nucleocapsid	NNP
cord-293701-u4ntxo0y	275	2	protein	protein	NN
cord-293701-u4ntxo0y	275	3	causes	cause	VBZ
cord-293701-u4ntxo0y	275	4	severe	severe	JJ
cord-293701-u4ntxo0y	275	5	pneumonia	pneumonia	NN
cord-293701-u4ntxo0y	275	6	in	in	IN
cord-293701-u4ntxo0y	275	7	mice	mouse	NNS
cord-293701-u4ntxo0y	275	8	infected	infect	VBN
cord-293701-u4ntxo0y	275	9	with	with	IN
cord-293701-u4ntxo0y	275	10	SARS	SARS	NNP
cord-293701-u4ntxo0y	275	11	-	-	HYPH
cord-293701-u4ntxo0y	275	12	CoV	CoV	NNP
cord-293701-u4ntxo0y	275	13	Immunization	Immunization	NNP
cord-293701-u4ntxo0y	275	14	with	with	IN
cord-293701-u4ntxo0y	276	1	SARS	SARS	NNP
cord-293701-u4ntxo0y	276	2	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	276	3	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	276	4	leads	lead	VBZ
cord-293701-u4ntxo0y	276	5	to	to	IN
cord-293701-u4ntxo0y	276	6	pulmonary	pulmonary	JJ
cord-293701-u4ntxo0y	276	7	immunopathology	immunopathology	NN
cord-293701-u4ntxo0y	276	8	on	on	IN
cord-293701-u4ntxo0y	276	9	challenge	challenge	NN
cord-293701-u4ntxo0y	276	10	with	with	IN
cord-293701-u4ntxo0y	276	11	the	the	DT
cord-293701-u4ntxo0y	276	12	SARS	SARS	NNP
cord-293701-u4ntxo0y	276	13	virus	virus	NN
cord-293701-u4ntxo0y	277	1	Immunodominant	Immunodominant	NNP
cord-293701-u4ntxo0y	277	2	SARS	SARS	NNP
cord-293701-u4ntxo0y	277	3	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	277	4	epitopes	epitope	NNS
cord-293701-u4ntxo0y	277	5	in	in	IN
cord-293701-u4ntxo0y	277	6	humans	human	NNS
cord-293701-u4ntxo0y	277	7	elicited	elicit	VBD
cord-293701-u4ntxo0y	277	8	both	both	DT
cord-293701-u4ntxo0y	277	9	enhancing	enhance	VBG
cord-293701-u4ntxo0y	277	10	and	and	CC
cord-293701-u4ntxo0y	277	11	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	277	12	effects	effect	NNS
cord-293701-u4ntxo0y	277	13	on	on	IN
cord-293701-u4ntxo0y	277	14	infection	infection	NN
cord-293701-u4ntxo0y	277	15	in	in	IN
cord-293701-u4ntxo0y	277	16	non	non	JJ
cord-293701-u4ntxo0y	277	17	-	-	JJ
cord-293701-u4ntxo0y	277	18	human	human	JJ
cord-293701-u4ntxo0y	277	19	primates	primate	NNS
cord-293701-u4ntxo0y	278	1	A	a	DT
cord-293701-u4ntxo0y	278	2	DNA	dna	NN
cord-293701-u4ntxo0y	278	3	vaccine	vaccine	NN
cord-293701-u4ntxo0y	278	4	induces	induce	VBZ
cord-293701-u4ntxo0y	278	5	SARS	SARS	NNP
cord-293701-u4ntxo0y	278	6	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	278	7	neutralization	neutralization	NN
cord-293701-u4ntxo0y	278	8	and	and	CC
cord-293701-u4ntxo0y	278	9	protective	protective	JJ
cord-293701-u4ntxo0y	278	10	immunity	immunity	NN
cord-293701-u4ntxo0y	278	11	in	in	IN
cord-293701-u4ntxo0y	278	12	mice	mouse	NNS
cord-293701-u4ntxo0y	279	1	A	a	DT
cord-293701-u4ntxo0y	279	2	SARS	SARS	NNP
cord-293701-u4ntxo0y	279	3	DNA	DNA	NNP
cord-293701-u4ntxo0y	279	4	vaccine	vaccine	NN
cord-293701-u4ntxo0y	279	5	induces	induce	VBZ
cord-293701-u4ntxo0y	279	6	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	279	7	antibody	antibody	NN
cord-293701-u4ntxo0y	279	8	and	and	CC
cord-293701-u4ntxo0y	279	9	cellular	cellular	JJ
cord-293701-u4ntxo0y	279	10	immune	immune	JJ
cord-293701-u4ntxo0y	279	11	responses	response	NNS
cord-293701-u4ntxo0y	279	12	in	in	IN
cord-293701-u4ntxo0y	279	13	healthy	healthy	JJ
cord-293701-u4ntxo0y	279	14	adults	adult	NNS
cord-293701-u4ntxo0y	279	15	in	in	IN
cord-293701-u4ntxo0y	279	16	a	a	DT
cord-293701-u4ntxo0y	279	17	phase	phase	NN
cord-293701-u4ntxo0y	279	18	I	-PRON-	PRP
cord-293701-u4ntxo0y	279	19	clinical	clinical	JJ
cord-293701-u4ntxo0y	279	20	trial	trial	NN
cord-293701-u4ntxo0y	279	21	Antibodies	Antibodies	NNPS
cord-293701-u4ntxo0y	279	22	against	against	IN
cord-293701-u4ntxo0y	279	23	trimeric	trimeric	NNP
cord-293701-u4ntxo0y	279	24	S	S	NNP
cord-293701-u4ntxo0y	279	25	glycoprotein	glycoprotein	NN
cord-293701-u4ntxo0y	279	26	protect	protect	VBP
cord-293701-u4ntxo0y	279	27	hamsters	hamster	NNS
cord-293701-u4ntxo0y	279	28	against	against	IN
cord-293701-u4ntxo0y	279	29	SARS	SARS	NNP
cord-293701-u4ntxo0y	279	30	-	-	HYPH
cord-293701-u4ntxo0y	279	31	CoV	CoV	NNP
cord-293701-u4ntxo0y	279	32	challenge	challenge	NN
cord-293701-u4ntxo0y	279	33	despite	despite	IN
cord-293701-u4ntxo0y	279	34	their	-PRON-	PRP$
cord-293701-u4ntxo0y	279	35	capacity	capacity	NN
cord-293701-u4ntxo0y	279	36	to	to	TO
cord-293701-u4ntxo0y	279	37	mediate	mediate	VB
cord-293701-u4ntxo0y	279	38	FcgammaRII	FcgammaRII	NNP
cord-293701-u4ntxo0y	279	39	-	-	HYPH
cord-293701-u4ntxo0y	279	40	dependent	dependent	JJ
cord-293701-u4ntxo0y	279	41	entry	entry	NN
cord-293701-u4ntxo0y	279	42	into	into	IN
cord-293701-u4ntxo0y	279	43	B	b	NN
cord-293701-u4ntxo0y	279	44	cells	cell	NNS
cord-293701-u4ntxo0y	279	45	in	in	IN
cord-293701-u4ntxo0y	279	46	vitro	vitro	FW
cord-293701-u4ntxo0y	279	47	Antibody	antibody	NN
cord-293701-u4ntxo0y	279	48	-	-	HYPH
cord-293701-u4ntxo0y	279	49	dependent	dependent	JJ
cord-293701-u4ntxo0y	279	50	infection	infection	NN
cord-293701-u4ntxo0y	279	51	of	of	IN
cord-293701-u4ntxo0y	279	52	human	human	JJ
cord-293701-u4ntxo0y	279	53	macrophages	macrophage	NNS
cord-293701-u4ntxo0y	279	54	by	by	IN
cord-293701-u4ntxo0y	279	55	severe	severe	JJ
cord-293701-u4ntxo0y	279	56	acute	acute	JJ
cord-293701-u4ntxo0y	279	57	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	279	58	syndrome	syndrome	NN
cord-293701-u4ntxo0y	279	59	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	279	60	Antibody	antibody	NN
cord-293701-u4ntxo0y	279	61	-	-	HYPH
cord-293701-u4ntxo0y	279	62	dependent	dependent	JJ
cord-293701-u4ntxo0y	279	63	SARS	SARS	NNP
cord-293701-u4ntxo0y	279	64	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	279	65	infection	infection	NN
cord-293701-u4ntxo0y	279	66	is	be	VBZ
cord-293701-u4ntxo0y	279	67	mediated	mediate	VBN
cord-293701-u4ntxo0y	279	68	by	by	IN
cord-293701-u4ntxo0y	279	69	antibodies	antibody	NNS
cord-293701-u4ntxo0y	279	70	against	against	IN
cord-293701-u4ntxo0y	279	71	spike	spike	NN
cord-293701-u4ntxo0y	279	72	proteins	protein	NNS
cord-293701-u4ntxo0y	280	1	Recent	recent	JJ
cord-293701-u4ntxo0y	280	2	advances	advance	NNS
cord-293701-u4ntxo0y	280	3	in	in	IN
cord-293701-u4ntxo0y	280	4	the	the	DT
cord-293701-u4ntxo0y	280	5	vaccine	vaccine	NN
cord-293701-u4ntxo0y	280	6	development	development	NN
cord-293701-u4ntxo0y	280	7	against	against	IN
cord-293701-u4ntxo0y	280	8	middle	middle	NNP
cord-293701-u4ntxo0y	280	9	east	east	NNP
cord-293701-u4ntxo0y	280	10	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	280	11	syndrome	syndrome	NN
cord-293701-u4ntxo0y	280	12	-	-	HYPH
cord-293701-u4ntxo0y	280	13	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	280	14	Vaccines	vaccine	NNS
cord-293701-u4ntxo0y	280	15	for	for	IN
cord-293701-u4ntxo0y	280	16	the	the	DT
cord-293701-u4ntxo0y	280	17	prevention	prevention	NN
cord-293701-u4ntxo0y	280	18	against	against	IN
cord-293701-u4ntxo0y	280	19	the	the	DT
cord-293701-u4ntxo0y	280	20	threat	threat	NN
cord-293701-u4ntxo0y	280	21	of	of	IN
cord-293701-u4ntxo0y	280	22	MERS	MERS	NNP
cord-293701-u4ntxo0y	280	23	-	-	HYPH
cord-293701-u4ntxo0y	280	24	CoV	CoV	NNP
cord-293701-u4ntxo0y	280	25	Immunization	Immunization	NNP
cord-293701-u4ntxo0y	280	26	with	with	IN
cord-293701-u4ntxo0y	280	27	inactivated	inactivate	VBN
cord-293701-u4ntxo0y	280	28	middle	middle	NNP
cord-293701-u4ntxo0y	280	29	east	east	NNP
cord-293701-u4ntxo0y	280	30	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	280	31	syndrome	syndrome	NN
cord-293701-u4ntxo0y	280	32	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	280	33	vaccine	vaccine	NN
cord-293701-u4ntxo0y	280	34	leads	lead	VBZ
cord-293701-u4ntxo0y	280	35	to	to	IN
cord-293701-u4ntxo0y	280	36	lung	lung	NN
cord-293701-u4ntxo0y	280	37	immunopathology	immunopathology	NN
cord-293701-u4ntxo0y	280	38	on	on	IN
cord-293701-u4ntxo0y	280	39	challenge	challenge	NN
cord-293701-u4ntxo0y	280	40	with	with	IN
cord-293701-u4ntxo0y	280	41	live	live	JJ
cord-293701-u4ntxo0y	280	42	virus	virus	NN
cord-293701-u4ntxo0y	280	43	Single	single	JJ
cord-293701-u4ntxo0y	280	44	-	-	HYPH
cord-293701-u4ntxo0y	280	45	dose	dose	NN
cord-293701-u4ntxo0y	280	46	,	,	,
cord-293701-u4ntxo0y	280	47	intranasal	intranasal	NN
cord-293701-u4ntxo0y	280	48	immunization	immunization	NN
cord-293701-u4ntxo0y	280	49	with	with	IN
cord-293701-u4ntxo0y	280	50	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	280	51	parainfluenza	parainfluenza	NNP
cord-293701-u4ntxo0y	280	52	virus	virus	NNP
cord-293701-u4ntxo0y	280	53	5	5	CD
cord-293701-u4ntxo0y	280	54	expressing	express	VBG
cord-293701-u4ntxo0y	280	55	middle	middle	NNP
cord-293701-u4ntxo0y	280	56	east	east	NNP
cord-293701-u4ntxo0y	280	57	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	280	58	syndrome	syndrome	NN
cord-293701-u4ntxo0y	280	59	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	280	60	(	(	-LRB-
cord-293701-u4ntxo0y	280	61	MERS	MERS	NNP
cord-293701-u4ntxo0y	280	62	-	-	HYPH
cord-293701-u4ntxo0y	280	63	CoV	CoV	NNP
cord-293701-u4ntxo0y	280	64	)	)	-RRB-
cord-293701-u4ntxo0y	281	1	spike	spike	NN
cord-293701-u4ntxo0y	281	2	protein	protein	NN
cord-293701-u4ntxo0y	281	3	protects	protect	VBZ
cord-293701-u4ntxo0y	281	4	mice	mouse	NNS
cord-293701-u4ntxo0y	281	5	from	from	IN
cord-293701-u4ntxo0y	281	6	fatal	fatal	JJ
cord-293701-u4ntxo0y	281	7	MERS	MERS	NNP
cord-293701-u4ntxo0y	281	8	-	-	HYPH
cord-293701-u4ntxo0y	281	9	CoV	CoV	NNP
cord-293701-u4ntxo0y	281	10	infection	infection	NN
cord-293701-u4ntxo0y	281	11	Molecular	Molecular	NNP
cord-293701-u4ntxo0y	281	12	mechanism	mechanism	NN
cord-293701-u4ntxo0y	281	13	for	for	IN
cord-293701-u4ntxo0y	281	14	antibodydependent	antibodydependent	NN
cord-293701-u4ntxo0y	281	15	enhancement	enhancement	NN
cord-293701-u4ntxo0y	281	16	of	of	IN
cord-293701-u4ntxo0y	281	17	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	281	18	entry	entry	NN
cord-293701-u4ntxo0y	281	19	Enhanced	enhance	VBN
cord-293701-u4ntxo0y	281	20	inflammation	inflammation	NN
cord-293701-u4ntxo0y	281	21	in	in	IN
cord-293701-u4ntxo0y	281	22	New	New	NNP
cord-293701-u4ntxo0y	281	23	Zealand	Zealand	NNP
cord-293701-u4ntxo0y	281	24	white	white	JJ
cord-293701-u4ntxo0y	281	25	rabbits	rabbit	NNS
cord-293701-u4ntxo0y	282	1	when	when	WRB
cord-293701-u4ntxo0y	282	2	MERS	MERS	NNP
cord-293701-u4ntxo0y	282	3	-	-	HYPH
cord-293701-u4ntxo0y	282	4	CoV	CoV	NNP
cord-293701-u4ntxo0y	282	5	reinfection	reinfection	NN
cord-293701-u4ntxo0y	282	6	occurs	occur	VBZ
cord-293701-u4ntxo0y	282	7	in	in	IN
cord-293701-u4ntxo0y	282	8	the	the	DT
cord-293701-u4ntxo0y	282	9	absence	absence	NN
cord-293701-u4ntxo0y	282	10	of	of	IN
cord-293701-u4ntxo0y	282	11	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	282	12	antibody	antibody	NN
cord-293701-u4ntxo0y	282	13	Safety	safety	NN
cord-293701-u4ntxo0y	282	14	and	and	CC
cord-293701-u4ntxo0y	282	15	immunogenicity	immunogenicity	NN
cord-293701-u4ntxo0y	282	16	of	of	IN
cord-293701-u4ntxo0y	282	17	an	an	DT
cord-293701-u4ntxo0y	282	18	anti	anti	JJ
cord-293701-u4ntxo0y	282	19	-	-	JJ
cord-293701-u4ntxo0y	282	20	Middle	Middle	NNP
cord-293701-u4ntxo0y	282	21	East	East	NNP
cord-293701-u4ntxo0y	282	22	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	282	23	syndrome	syndrome	NN
cord-293701-u4ntxo0y	282	24	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	282	25	DNA	dna	NN
cord-293701-u4ntxo0y	282	26	vaccine	vaccine	NN
cord-293701-u4ntxo0y	282	27	:	:	:
cord-293701-u4ntxo0y	282	28	a	a	DT
cord-293701-u4ntxo0y	282	29	phase	phase	NN
cord-293701-u4ntxo0y	282	30	1	1	CD
cord-293701-u4ntxo0y	282	31	,	,	,
cord-293701-u4ntxo0y	282	32	open	open	JJ
cord-293701-u4ntxo0y	282	33	-	-	HYPH
cord-293701-u4ntxo0y	282	34	label	label	NN
cord-293701-u4ntxo0y	282	35	,	,	,
cord-293701-u4ntxo0y	282	36	single	single	JJ
cord-293701-u4ntxo0y	282	37	-	-	HYPH
cord-293701-u4ntxo0y	282	38	arm	arm	NN
cord-293701-u4ntxo0y	282	39	,	,	,
cord-293701-u4ntxo0y	282	40	dose	dose	NN
cord-293701-u4ntxo0y	282	41	-	-	HYPH
cord-293701-u4ntxo0y	282	42	escalation	escalation	NN
cord-293701-u4ntxo0y	282	43	trial	trial	NN
cord-293701-u4ntxo0y	282	44	Safety	safety	NN
cord-293701-u4ntxo0y	282	45	and	and	CC
cord-293701-u4ntxo0y	282	46	immunogenicity	immunogenicity	NN
cord-293701-u4ntxo0y	282	47	of	of	IN
cord-293701-u4ntxo0y	282	48	a	a	DT
cord-293701-u4ntxo0y	282	49	modified	modify	VBN
cord-293701-u4ntxo0y	282	50	vaccinia	vaccinia	NN
cord-293701-u4ntxo0y	282	51	virus	virus	NN
cord-293701-u4ntxo0y	282	52	Ankara	Ankara	NNP
cord-293701-u4ntxo0y	282	53	vector	vector	NN
cord-293701-u4ntxo0y	282	54	vaccine	vaccine	NN
cord-293701-u4ntxo0y	282	55	candidate	candidate	NN
cord-293701-u4ntxo0y	282	56	for	for	IN
cord-293701-u4ntxo0y	282	57	Middle	Middle	NNP
cord-293701-u4ntxo0y	282	58	East	East	NNP
cord-293701-u4ntxo0y	282	59	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	282	60	syndrome	syndrome	NN
cord-293701-u4ntxo0y	282	61	:	:	:
cord-293701-u4ntxo0y	282	62	an	an	DT
cord-293701-u4ntxo0y	282	63	open	open	JJ
cord-293701-u4ntxo0y	282	64	-	-	HYPH
cord-293701-u4ntxo0y	282	65	label	label	NN
cord-293701-u4ntxo0y	282	66	,	,	,
cord-293701-u4ntxo0y	282	67	phase	phase	NN
cord-293701-u4ntxo0y	282	68	1	1	CD
cord-293701-u4ntxo0y	282	69	trial	trial	NN
cord-293701-u4ntxo0y	282	70	Safety	safety	NN
cord-293701-u4ntxo0y	282	71	and	and	CC
cord-293701-u4ntxo0y	282	72	immunogenicity	immunogenicity	NN
cord-293701-u4ntxo0y	282	73	of	of	IN
cord-293701-u4ntxo0y	282	74	a	a	DT
cord-293701-u4ntxo0y	282	75	candidate	candidate	NN
cord-293701-u4ntxo0y	282	76	Middle	Middle	NNP
cord-293701-u4ntxo0y	282	77	East	East	NNP
cord-293701-u4ntxo0y	282	78	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	282	79	syndrome	syndrome	NN
cord-293701-u4ntxo0y	282	80	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	282	81	viral	viral	RB
cord-293701-u4ntxo0y	282	82	-	-	HYPH
cord-293701-u4ntxo0y	282	83	vectored	vectore	VBN
cord-293701-u4ntxo0y	282	84	vaccine	vaccine	NN
cord-293701-u4ntxo0y	282	85	:	:	:
cord-293701-u4ntxo0y	282	86	a	a	DT
cord-293701-u4ntxo0y	282	87	dose	dose	NN
cord-293701-u4ntxo0y	282	88	-	-	HYPH
cord-293701-u4ntxo0y	282	89	escalation	escalation	NN
cord-293701-u4ntxo0y	282	90	,	,	,
cord-293701-u4ntxo0y	282	91	open	open	JJ
cord-293701-u4ntxo0y	282	92	-	-	HYPH
cord-293701-u4ntxo0y	282	93	label	label	NN
cord-293701-u4ntxo0y	282	94	,	,	,
cord-293701-u4ntxo0y	282	95	non	non	JJ
cord-293701-u4ntxo0y	282	96	-	-	JJ
cord-293701-u4ntxo0y	282	97	randomised	randomised	JJ
cord-293701-u4ntxo0y	282	98	,	,	,
cord-293701-u4ntxo0y	282	99	uncontrolled	uncontrolled	JJ
cord-293701-u4ntxo0y	282	100	,	,	,
cord-293701-u4ntxo0y	282	101	phase	phase	NN
cord-293701-u4ntxo0y	282	102	1	1	CD
cord-293701-u4ntxo0y	282	103	trial	trial	NN
cord-293701-u4ntxo0y	282	104	Antibody	antibody	NN
cord-293701-u4ntxo0y	282	105	-	-	HYPH
cord-293701-u4ntxo0y	282	106	dependent	dependent	JJ
cord-293701-u4ntxo0y	282	107	enhancement	enhancement	NN
cord-293701-u4ntxo0y	282	108	of	of	IN
cord-293701-u4ntxo0y	282	109	Ebola	Ebola	NNP
cord-293701-u4ntxo0y	282	110	virus	virus	NN
cord-293701-u4ntxo0y	282	111	infection	infection	NN
cord-293701-u4ntxo0y	282	112	Infection	infection	NN
cord-293701-u4ntxo0y	282	113	of	of	IN
cord-293701-u4ntxo0y	282	114	human	human	JJ
cord-293701-u4ntxo0y	282	115	lymphomononuclear	lymphomononuclear	NN
cord-293701-u4ntxo0y	282	116	cells	cell	NNS
cord-293701-u4ntxo0y	282	117	by	by	IN
cord-293701-u4ntxo0y	282	118	SARS	SARS	NNP
cord-293701-u4ntxo0y	282	119	-	-	HYPH
cord-293701-u4ntxo0y	282	120	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	282	121	Differential	differential	JJ
cord-293701-u4ntxo0y	282	122	chemokine	chemokine	NN
cord-293701-u4ntxo0y	282	123	expression	expression	NN
cord-293701-u4ntxo0y	282	124	following	follow	VBG
cord-293701-u4ntxo0y	282	125	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	282	126	virus	virus	NN
cord-293701-u4ntxo0y	282	127	infection	infection	NN
cord-293701-u4ntxo0y	282	128	reflects	reflect	VBZ
cord-293701-u4ntxo0y	282	129	Th1-or	Th1-or	NNP
cord-293701-u4ntxo0y	282	130	Th2-biased	th2-biase	VBN
cord-293701-u4ntxo0y	282	131	immunopathology	immunopathology	NN
cord-293701-u4ntxo0y	282	132	Novel	novel	JJ
cord-293701-u4ntxo0y	282	133	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	282	134	infection	infection	NN
cord-293701-u4ntxo0y	282	135	(	(	-LRB-
cord-293701-u4ntxo0y	282	136	COVID-19	covid-19	VB
cord-293701-u4ntxo0y	282	137	)	)	-RRB-
cord-293701-u4ntxo0y	282	138	in	in	IN
cord-293701-u4ntxo0y	282	139	humans	human	NNS
cord-293701-u4ntxo0y	282	140	:	:	:
cord-293701-u4ntxo0y	282	141	a	a	DT
cord-293701-u4ntxo0y	282	142	scoping	scoping	NN
cord-293701-u4ntxo0y	282	143	review	review	NN
cord-293701-u4ntxo0y	282	144	and	and	CC
cord-293701-u4ntxo0y	282	145	meta	meta	NNP
cord-293701-u4ntxo0y	282	146	-	-	HYPH
cord-293701-u4ntxo0y	282	147	analysis	analysis	NN
cord-293701-u4ntxo0y	282	148	Dexamethasone	Dexamethasone	NNP
cord-293701-u4ntxo0y	282	149	for	for	IN
cord-293701-u4ntxo0y	282	150	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	282	151	:	:	:
cord-293701-u4ntxo0y	282	152	preliminary	preliminary	JJ
cord-293701-u4ntxo0y	282	153	findings	finding	NNS
cord-293701-u4ntxo0y	283	1	Temporal	temporal	JJ
cord-293701-u4ntxo0y	283	2	profiles	profile	NNS
cord-293701-u4ntxo0y	283	3	of	of	IN
cord-293701-u4ntxo0y	283	4	viral	viral	JJ
cord-293701-u4ntxo0y	283	5	load	load	NN
cord-293701-u4ntxo0y	283	6	in	in	IN
cord-293701-u4ntxo0y	283	7	posterior	posterior	JJ
cord-293701-u4ntxo0y	283	8	oropharyngeal	oropharyngeal	JJ
cord-293701-u4ntxo0y	283	9	saliva	saliva	NN
cord-293701-u4ntxo0y	283	10	samples	sample	NNS
cord-293701-u4ntxo0y	283	11	and	and	CC
cord-293701-u4ntxo0y	283	12	serum	serum	NN
cord-293701-u4ntxo0y	283	13	antibody	antibody	NN
cord-293701-u4ntxo0y	283	14	responses	response	NNS
cord-293701-u4ntxo0y	283	15	during	during	IN
cord-293701-u4ntxo0y	283	16	infection	infection	NN
cord-293701-u4ntxo0y	283	17	by	by	IN
cord-293701-u4ntxo0y	283	18	SARS	SARS	NNP
cord-293701-u4ntxo0y	283	19	-	-	HYPH
cord-293701-u4ntxo0y	283	20	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	283	21	:	:	:
cord-293701-u4ntxo0y	283	22	an	an	DT
cord-293701-u4ntxo0y	283	23	observational	observational	JJ
cord-293701-u4ntxo0y	283	24	cohort	cohort	NN
cord-293701-u4ntxo0y	283	25	study	study	NN
cord-293701-u4ntxo0y	283	26	Detection	Detection	NNP
cord-293701-u4ntxo0y	283	27	of	of	IN
cord-293701-u4ntxo0y	283	28	SARS	SARS	NNP
cord-293701-u4ntxo0y	283	29	-	-	HYPH
cord-293701-u4ntxo0y	283	30	CoV-2-specific	CoV-2-specific	NNP
cord-293701-u4ntxo0y	283	31	humoral	humoral	JJ
cord-293701-u4ntxo0y	283	32	and	and	CC
cord-293701-u4ntxo0y	283	33	cellular	cellular	JJ
cord-293701-u4ntxo0y	283	34	immunity	immunity	NN
cord-293701-u4ntxo0y	283	35	in	in	IN
cord-293701-u4ntxo0y	283	36	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	283	37	convalescent	convalescent	JJ
cord-293701-u4ntxo0y	283	38	individuals	individual	NNS
cord-293701-u4ntxo0y	283	39	Viral	viral	JJ
cord-293701-u4ntxo0y	283	40	dynamics	dynamic	NNS
cord-293701-u4ntxo0y	283	41	and	and	CC
cord-293701-u4ntxo0y	283	42	immune	immune	JJ
cord-293701-u4ntxo0y	283	43	correlates	correlate	NNS
cord-293701-u4ntxo0y	283	44	of	of	IN
cord-293701-u4ntxo0y	283	45	COVID-19	covid-19	JJ
cord-293701-u4ntxo0y	283	46	disease	disease	NN
cord-293701-u4ntxo0y	283	47	severity	severity	NN
cord-293701-u4ntxo0y	283	48	Profile	Profile	NNP
cord-293701-u4ntxo0y	283	49	of	of	IN
cord-293701-u4ntxo0y	283	50	IgG	IgG	NNP
cord-293701-u4ntxo0y	283	51	and	and	CC
cord-293701-u4ntxo0y	283	52	IgM	IgM	NNP
cord-293701-u4ntxo0y	283	53	antibodies	antibody	NNS
cord-293701-u4ntxo0y	283	54	against	against	IN
cord-293701-u4ntxo0y	283	55	severe	severe	JJ
cord-293701-u4ntxo0y	283	56	acute	acute	JJ
cord-293701-u4ntxo0y	283	57	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	283	58	syndrome	syndrome	NN
cord-293701-u4ntxo0y	283	59	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	283	60	2	2	CD
cord-293701-u4ntxo0y	284	1	(	(	-LRB-
cord-293701-u4ntxo0y	284	2	SARS	SARS	NNP
cord-293701-u4ntxo0y	284	3	-	-	HYPH
cord-293701-u4ntxo0y	284	4	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	284	5	)	)	-RRB-
cord-293701-u4ntxo0y	284	6	Nevada	Nevada	NNP
cord-293701-u4ntxo0y	284	7	State	State	NNP
cord-293701-u4ntxo0y	284	8	Public	Public	NNP
cord-293701-u4ntxo0y	284	9	Health	Health	NNP
cord-293701-u4ntxo0y	284	10	Lab	Lab	NNP
cord-293701-u4ntxo0y	284	11	-	-	HYPH
cord-293701-u4ntxo0y	284	12	led	lead	VBN
cord-293701-u4ntxo0y	284	13	team	team	NN
cord-293701-u4ntxo0y	284	14	studying	study	VBG
cord-293701-u4ntxo0y	284	15	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	284	16	reinfection	reinfection	NN
cord-293701-u4ntxo0y	284	17	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	284	18	Re	re	NN
cord-293701-u4ntxo0y	284	19	-	-	NN
cord-293701-u4ntxo0y	284	20	infection	infection	NN
cord-293701-u4ntxo0y	284	21	by	by	IN
cord-293701-u4ntxo0y	284	22	a	a	DT
cord-293701-u4ntxo0y	284	23	phylogenetically	phylogenetically	RB
cord-293701-u4ntxo0y	284	24	distinct	distinct	JJ
cord-293701-u4ntxo0y	284	25	SARS	SARS	NNP
cord-293701-u4ntxo0y	284	26	-	-	HYPH
cord-293701-u4ntxo0y	284	27	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	284	28	variant	variant	NN
cord-293701-u4ntxo0y	284	29	,	,	,
cord-293701-u4ntxo0y	284	30	first	first	RB
cord-293701-u4ntxo0y	284	31	confirmed	confirm	VBN
cord-293701-u4ntxo0y	284	32	event	event	NN
cord-293701-u4ntxo0y	284	33	in	in	IN
cord-293701-u4ntxo0y	284	34	South	South	NNP
cord-293701-u4ntxo0y	284	35	America	America	NNP
cord-293701-u4ntxo0y	284	36	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	284	37	re	re	NN
cord-293701-u4ntxo0y	284	38	-	-	NN
cord-293701-u4ntxo0y	284	39	infection	infection	NN
cord-293701-u4ntxo0y	284	40	by	by	IN
cord-293701-u4ntxo0y	284	41	a	a	DT
cord-293701-u4ntxo0y	284	42	phylogenetically	phylogenetically	RB
cord-293701-u4ntxo0y	284	43	distinct	distinct	JJ
cord-293701-u4ntxo0y	284	44	SARS	SARS	NNP
cord-293701-u4ntxo0y	284	45	-	-	HYPH
cord-293701-u4ntxo0y	284	46	coronavirus-2	coronavirus-2	NNP
cord-293701-u4ntxo0y	284	47	strain	strain	NN
cord-293701-u4ntxo0y	284	48	confirmed	confirm	VBN
cord-293701-u4ntxo0y	284	49	by	by	IN
cord-293701-u4ntxo0y	284	50	whole	whole	JJ
cord-293701-u4ntxo0y	284	51	genome	genome	NN
cord-293701-u4ntxo0y	284	52	sequencing	sequencing	NN
cord-293701-u4ntxo0y	284	53	Symptomatic	symptomatic	JJ
cord-293701-u4ntxo0y	284	54	SARS	SARS	NNP
cord-293701-u4ntxo0y	284	55	-	-	HYPH
cord-293701-u4ntxo0y	284	56	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	284	57	reinfection	reinfection	NN
cord-293701-u4ntxo0y	284	58	by	by	IN
cord-293701-u4ntxo0y	284	59	a	a	DT
cord-293701-u4ntxo0y	284	60	phylogenetically	phylogenetically	RB
cord-293701-u4ntxo0y	284	61	distinct	distinct	JJ
cord-293701-u4ntxo0y	284	62	strain	strain	NN
cord-293701-u4ntxo0y	284	63	Identification	identification	NN
cord-293701-u4ntxo0y	284	64	of	of	IN
cord-293701-u4ntxo0y	284	65	human	human	JJ
cord-293701-u4ntxo0y	284	66	single	single	JJ
cord-293701-u4ntxo0y	284	67	-	-	HYPH
cord-293701-u4ntxo0y	284	68	domain	domain	NN
cord-293701-u4ntxo0y	284	69	antibodies	antibody	NNS
cord-293701-u4ntxo0y	284	70	against	against	IN
cord-293701-u4ntxo0y	284	71	SARS	SARS	NNP
cord-293701-u4ntxo0y	284	72	-	-	HYPH
cord-293701-u4ntxo0y	284	73	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	284	74	Vaccine	Vaccine	NNP
cord-293701-u4ntxo0y	284	75	efficacy	efficacy	NN
cord-293701-u4ntxo0y	284	76	in	in	IN
cord-293701-u4ntxo0y	284	77	senescent	senescent	JJ
cord-293701-u4ntxo0y	284	78	mice	mouse	NNS
cord-293701-u4ntxo0y	284	79	challenged	challenge	VBN
cord-293701-u4ntxo0y	284	80	with	with	IN
cord-293701-u4ntxo0y	284	81	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	284	82	SARS	SARS	NNP
cord-293701-u4ntxo0y	284	83	-	-	HYPH
cord-293701-u4ntxo0y	284	84	CoV	CoV	NNP
cord-293701-u4ntxo0y	284	85	bearing	bearing	NN
cord-293701-u4ntxo0y	284	86	epidemic	epidemic	NN
cord-293701-u4ntxo0y	284	87	and	and	CC
cord-293701-u4ntxo0y	284	88	zoonotic	zoonotic	JJ
cord-293701-u4ntxo0y	284	89	spike	spike	NN
cord-293701-u4ntxo0y	284	90	variants	variant	NNS
cord-293701-u4ntxo0y	284	91	Comorbidity	comorbidity	NN
cord-293701-u4ntxo0y	284	92	and	and	CC
cord-293701-u4ntxo0y	284	93	its	-PRON-	PRP$
cord-293701-u4ntxo0y	284	94	impact	impact	NN
cord-293701-u4ntxo0y	284	95	on	on	IN
cord-293701-u4ntxo0y	284	96	1590	1590	CD
cord-293701-u4ntxo0y	284	97	patients	patient	NNS
cord-293701-u4ntxo0y	284	98	with	with	IN
cord-293701-u4ntxo0y	284	99	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	284	100	in	in	IN
cord-293701-u4ntxo0y	284	101	China	China	NNP
cord-293701-u4ntxo0y	284	102	:	:	:
cord-293701-u4ntxo0y	284	103	a	a	DT
cord-293701-u4ntxo0y	284	104	nationwide	nationwide	JJ
cord-293701-u4ntxo0y	284	105	analysis	analysis	NN
cord-293701-u4ntxo0y	284	106	Consensus	Consensus	NNP
cord-293701-u4ntxo0y	284	107	summary	summary	NN
cord-293701-u4ntxo0y	284	108	report	report	NN
cord-293701-u4ntxo0y	284	109	for	for	IN
cord-293701-u4ntxo0y	284	110	CEPI	CEPI	NNP
cord-293701-u4ntxo0y	284	111	/	/	SYM
cord-293701-u4ntxo0y	284	112	BC	BC	NNP
cord-293701-u4ntxo0y	284	113	March	March	NNP
cord-293701-u4ntxo0y	284	114	12	12	CD
cord-293701-u4ntxo0y	284	115	-	-	SYM
cord-293701-u4ntxo0y	284	116	13	13	CD
cord-293701-u4ntxo0y	284	117	,	,	,
cord-293701-u4ntxo0y	284	118	2020	2020	CD
cord-293701-u4ntxo0y	284	119	meeting	meeting	NN
cord-293701-u4ntxo0y	284	120	:	:	:
cord-293701-u4ntxo0y	284	121	assessment	assessment	NN
cord-293701-u4ntxo0y	284	122	of	of	IN
cord-293701-u4ntxo0y	284	123	risk	risk	NN
cord-293701-u4ntxo0y	284	124	of	of	IN
cord-293701-u4ntxo0y	284	125	disease	disease	NN
cord-293701-u4ntxo0y	284	126	enhancement	enhancement	NN
cord-293701-u4ntxo0y	284	127	with	with	IN
cord-293701-u4ntxo0y	284	128	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	284	129	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	284	130	COVID-19	covid-19	VBP
cord-293701-u4ntxo0y	284	131	:	:	:
cord-293701-u4ntxo0y	284	132	immunopathology	immunopathology	NN
cord-293701-u4ntxo0y	284	133	and	and	CC
cord-293701-u4ntxo0y	284	134	its	-PRON-	PRP$
cord-293701-u4ntxo0y	284	135	implications	implication	NNS
cord-293701-u4ntxo0y	284	136	for	for	IN
cord-293701-u4ntxo0y	284	137	therapy	therapy	NN
cord-293701-u4ntxo0y	284	138	SARS	SARS	NNP
cord-293701-u4ntxo0y	284	139	-	-	HYPH
cord-293701-u4ntxo0y	284	140	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	284	141	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	284	142	:	:	:
cord-293701-u4ntxo0y	284	143	'	'	``
cord-293701-u4ntxo0y	284	144	warp	warp	NN
cord-293701-u4ntxo0y	284	145	speed	speed	NN
cord-293701-u4ntxo0y	284	146	'	'	''
cord-293701-u4ntxo0y	284	147	needs	need	VBZ
cord-293701-u4ntxo0y	284	148	mind	mind	NN
cord-293701-u4ntxo0y	284	149	melds	meld	VBZ
cord-293701-u4ntxo0y	284	150	not	not	RB
cord-293701-u4ntxo0y	284	151	warped	warped	JJ
cord-293701-u4ntxo0y	284	152	minds	mind	NNS
cord-293701-u4ntxo0y	284	153	Receptor	receptor	NN
cord-293701-u4ntxo0y	284	154	-	-	HYPH
cord-293701-u4ntxo0y	284	155	binding	bind	VBG
cord-293701-u4ntxo0y	284	156	domain	domain	NN
cord-293701-u4ntxo0y	284	157	of	of	IN
cord-293701-u4ntxo0y	284	158	SARS	SARS	NNP
cord-293701-u4ntxo0y	284	159	-	-	HYPH
cord-293701-u4ntxo0y	284	160	CoV	CoV	NNP
cord-293701-u4ntxo0y	284	161	spike	spike	NN
cord-293701-u4ntxo0y	284	162	protein	protein	NN
cord-293701-u4ntxo0y	284	163	induces	induce	VBZ
cord-293701-u4ntxo0y	284	164	long	long	JJ
cord-293701-u4ntxo0y	284	165	-	-	HYPH
cord-293701-u4ntxo0y	284	166	term	term	NN
cord-293701-u4ntxo0y	284	167	protective	protective	JJ
cord-293701-u4ntxo0y	284	168	immunity	immunity	NN
cord-293701-u4ntxo0y	284	169	in	in	IN
cord-293701-u4ntxo0y	284	170	an	an	DT
cord-293701-u4ntxo0y	284	171	animal	animal	NN
cord-293701-u4ntxo0y	284	172	model	model	NN
cord-293701-u4ntxo0y	284	173	FDA	FDA	NNP
cord-293701-u4ntxo0y	284	174	.	.	.
cord-293701-u4ntxo0y	285	1	Recommendations	recommendation	NNS
cord-293701-u4ntxo0y	285	2	for	for	IN
cord-293701-u4ntxo0y	285	3	Investigational	Investigational	NNP
cord-293701-u4ntxo0y	285	4	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	285	5	Convalescent	Convalescent	NNP
cord-293701-u4ntxo0y	285	6	Plasma	Plasma	NNP
cord-293701-u4ntxo0y	285	7	Yeast	Yeast	NNP
cord-293701-u4ntxo0y	285	8	-	-	HYPH
cord-293701-u4ntxo0y	285	9	expressed	express	VBN
cord-293701-u4ntxo0y	285	10	SARS	SARS	NNP
cord-293701-u4ntxo0y	285	11	-	-	HYPH
cord-293701-u4ntxo0y	285	12	CoV	CoV	NNP
cord-293701-u4ntxo0y	285	13	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	285	14	receptor	receptor	NN
cord-293701-u4ntxo0y	285	15	-	-	HYPH
cord-293701-u4ntxo0y	285	16	binding	bind	VBG
cord-293701-u4ntxo0y	285	17	domain	domain	NN
cord-293701-u4ntxo0y	285	18	(	(	-LRB-
cord-293701-u4ntxo0y	285	19	RBD219-N1	RBD219-N1	NNP
cord-293701-u4ntxo0y	285	20	)	)	-RRB-
cord-293701-u4ntxo0y	285	21	formulated	formulate	VBN
cord-293701-u4ntxo0y	285	22	with	with	IN
cord-293701-u4ntxo0y	285	23	alum	alum	NN
cord-293701-u4ntxo0y	285	24	induces	induce	VBZ
cord-293701-u4ntxo0y	285	25	protective	protective	JJ
cord-293701-u4ntxo0y	285	26	immunity	immunity	NN
cord-293701-u4ntxo0y	285	27	and	and	CC
cord-293701-u4ntxo0y	285	28	reduces	reduce	VBZ
cord-293701-u4ntxo0y	285	29	immune	immune	JJ
cord-293701-u4ntxo0y	285	30	enhancement	enhancement	NN
cord-293701-u4ntxo0y	285	31	Longitudinal	longitudinal	JJ
cord-293701-u4ntxo0y	285	32	evaluation	evaluation	NN
cord-293701-u4ntxo0y	285	33	and	and	CC
cord-293701-u4ntxo0y	285	34	decline	decline	NN
cord-293701-u4ntxo0y	285	35	of	of	IN
cord-293701-u4ntxo0y	285	36	antibody	antibody	NN
cord-293701-u4ntxo0y	285	37	responses	response	NNS
cord-293701-u4ntxo0y	285	38	in	in	IN
cord-293701-u4ntxo0y	285	39	SARS	SARS	NNP
cord-293701-u4ntxo0y	285	40	-	-	HYPH
cord-293701-u4ntxo0y	285	41	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	285	42	infection	infection	NN
cord-293701-u4ntxo0y	286	1	Humoral	Humoral	NNP
cord-293701-u4ntxo0y	286	2	immune	immune	JJ
cord-293701-u4ntxo0y	286	3	response	response	NN
cord-293701-u4ntxo0y	286	4	to	to	IN
cord-293701-u4ntxo0y	286	5	SARS	SARS	NNP
cord-293701-u4ntxo0y	286	6	-	-	HYPH
cord-293701-u4ntxo0y	286	7	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	286	8	in	in	IN
cord-293701-u4ntxo0y	286	9	Iceland	Iceland	NNP
cord-293701-u4ntxo0y	286	10	Humoral	Humoral	NNP
cord-293701-u4ntxo0y	286	11	and	and	CC
cord-293701-u4ntxo0y	286	12	circulating	circulate	VBG
cord-293701-u4ntxo0y	286	13	follicular	follicular	JJ
cord-293701-u4ntxo0y	286	14	helper	helper	NN
cord-293701-u4ntxo0y	286	15	T	t	NN
cord-293701-u4ntxo0y	286	16	cell	cell	NN
cord-293701-u4ntxo0y	286	17	responses	response	NNS
cord-293701-u4ntxo0y	286	18	in	in	IN
cord-293701-u4ntxo0y	286	19	recovered	recover	VBN
cord-293701-u4ntxo0y	286	20	patients	patient	NNS
cord-293701-u4ntxo0y	286	21	with	with	IN
cord-293701-u4ntxo0y	286	22	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	286	23	Identification	Identification	NNP
cord-293701-u4ntxo0y	286	24	of	of	IN
cord-293701-u4ntxo0y	286	25	immunodominant	immunodominant	JJ
cord-293701-u4ntxo0y	286	26	sites	site	NNS
cord-293701-u4ntxo0y	286	27	on	on	IN
cord-293701-u4ntxo0y	286	28	the	the	DT
cord-293701-u4ntxo0y	286	29	spike	spike	NN
cord-293701-u4ntxo0y	286	30	protein	protein	NN
cord-293701-u4ntxo0y	286	31	of	of	IN
cord-293701-u4ntxo0y	286	32	severe	severe	JJ
cord-293701-u4ntxo0y	286	33	acute	acute	JJ
cord-293701-u4ntxo0y	286	34	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	286	35	syndrome	syndrome	NN
cord-293701-u4ntxo0y	286	36	(	(	-LRB-
cord-293701-u4ntxo0y	286	37	SARS	SARS	NNP
cord-293701-u4ntxo0y	286	38	)	)	-RRB-
cord-293701-u4ntxo0y	286	39	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	286	40	:	:	:
cord-293701-u4ntxo0y	286	41	implication	implication	NN
cord-293701-u4ntxo0y	286	42	for	for	IN
cord-293701-u4ntxo0y	286	43	developing	develop	VBG
cord-293701-u4ntxo0y	286	44	SARS	SARS	NNP
cord-293701-u4ntxo0y	286	45	diagnostics	diagnostic	NNS
cord-293701-u4ntxo0y	286	46	and	and	CC
cord-293701-u4ntxo0y	286	47	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	286	48	Neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	286	49	human	human	JJ
cord-293701-u4ntxo0y	286	50	monoclonal	monoclonal	JJ
cord-293701-u4ntxo0y	286	51	antibodies	antibody	NNS
cord-293701-u4ntxo0y	286	52	to	to	TO
cord-293701-u4ntxo0y	286	53	severe	severe	JJ
cord-293701-u4ntxo0y	286	54	acute	acute	JJ
cord-293701-u4ntxo0y	286	55	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	286	56	syndrome	syndrome	NN
cord-293701-u4ntxo0y	286	57	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	286	58	:	:	:
cord-293701-u4ntxo0y	286	59	target	target	NN
cord-293701-u4ntxo0y	286	60	,	,	,
cord-293701-u4ntxo0y	286	61	mechanism	mechanism	NN
cord-293701-u4ntxo0y	286	62	of	of	IN
cord-293701-u4ntxo0y	286	63	action	action	NN
cord-293701-u4ntxo0y	286	64	,	,	,
cord-293701-u4ntxo0y	286	65	and	and	CC
cord-293701-u4ntxo0y	286	66	therapeutic	therapeutic	JJ
cord-293701-u4ntxo0y	286	67	potential	potential	JJ
cord-293701-u4ntxo0y	286	68	Intranasal	Intranasal	NNP
cord-293701-u4ntxo0y	286	69	vaccination	vaccination	NN
cord-293701-u4ntxo0y	286	70	of	of	IN
cord-293701-u4ntxo0y	286	71	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	286	72	adeno	adeno	NN
cord-293701-u4ntxo0y	286	73	-	-	HYPH
cord-293701-u4ntxo0y	286	74	associated	associate	VBN
cord-293701-u4ntxo0y	286	75	virus	virus	NN
cord-293701-u4ntxo0y	286	76	encoding	encode	VBG
cord-293701-u4ntxo0y	286	77	receptor	receptor	NN
cord-293701-u4ntxo0y	286	78	-	-	HYPH
cord-293701-u4ntxo0y	286	79	binding	bind	VBG
cord-293701-u4ntxo0y	286	80	domain	domain	NN
cord-293701-u4ntxo0y	286	81	of	of	IN
cord-293701-u4ntxo0y	286	82	severe	severe	JJ
cord-293701-u4ntxo0y	286	83	acute	acute	JJ
cord-293701-u4ntxo0y	286	84	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	286	85	syndrome	syndrome	NN
cord-293701-u4ntxo0y	286	86	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	286	87	(	(	-LRB-
cord-293701-u4ntxo0y	286	88	SARS	SARS	NNP
cord-293701-u4ntxo0y	286	89	-	-	HYPH
cord-293701-u4ntxo0y	286	90	CoV	CoV	NNP
cord-293701-u4ntxo0y	286	91	)	)	-RRB-
cord-293701-u4ntxo0y	287	1	spike	spike	NN
cord-293701-u4ntxo0y	287	2	protein	protein	NN
cord-293701-u4ntxo0y	287	3	induces	induce	VBZ
cord-293701-u4ntxo0y	287	4	strong	strong	JJ
cord-293701-u4ntxo0y	287	5	mucosal	mucosal	JJ
cord-293701-u4ntxo0y	287	6	immune	immune	JJ
cord-293701-u4ntxo0y	287	7	responses	response	NNS
cord-293701-u4ntxo0y	287	8	and	and	CC
cord-293701-u4ntxo0y	287	9	provides	provide	VBZ
cord-293701-u4ntxo0y	287	10	long	long	JJ
cord-293701-u4ntxo0y	287	11	-	-	HYPH
cord-293701-u4ntxo0y	287	12	term	term	NN
cord-293701-u4ntxo0y	287	13	protection	protection	NN
cord-293701-u4ntxo0y	287	14	against	against	IN
cord-293701-u4ntxo0y	287	15	SARS	SARS	NNP
cord-293701-u4ntxo0y	287	16	-	-	HYPH
cord-293701-u4ntxo0y	287	17	CoV	CoV	NNP
cord-293701-u4ntxo0y	287	18	infection	infection	NN
cord-293701-u4ntxo0y	287	19	Receptorbinding	Receptorbinding	NNP
cord-293701-u4ntxo0y	287	20	domains	domain	NNS
cord-293701-u4ntxo0y	287	21	of	of	IN
cord-293701-u4ntxo0y	287	22	spike	spike	NN
cord-293701-u4ntxo0y	287	23	proteins	protein	NNS
cord-293701-u4ntxo0y	287	24	of	of	IN
cord-293701-u4ntxo0y	287	25	emerging	emerge	VBG
cord-293701-u4ntxo0y	287	26	or	or	CC
cord-293701-u4ntxo0y	287	27	re	re	VB
cord-293701-u4ntxo0y	287	28	-	-	JJ
cord-293701-u4ntxo0y	287	29	emerging	emerge	VBG
cord-293701-u4ntxo0y	287	30	viruses	virus	NNS
cord-293701-u4ntxo0y	287	31	as	as	IN
cord-293701-u4ntxo0y	287	32	targets	target	NNS
cord-293701-u4ntxo0y	287	33	for	for	IN
cord-293701-u4ntxo0y	287	34	development	development	NN
cord-293701-u4ntxo0y	287	35	of	of	IN
cord-293701-u4ntxo0y	287	36	antiviral	antiviral	JJ
cord-293701-u4ntxo0y	287	37	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	287	38	Receptor	receptor	NN
cord-293701-u4ntxo0y	287	39	-	-	HYPH
cord-293701-u4ntxo0y	287	40	binding	bind	VBG
cord-293701-u4ntxo0y	287	41	domain	domain	NN
cord-293701-u4ntxo0y	287	42	of	of	IN
cord-293701-u4ntxo0y	287	43	SARS	SARS	NNP
cord-293701-u4ntxo0y	287	44	-	-	HYPH
cord-293701-u4ntxo0y	287	45	CoV	CoV	NNP
cord-293701-u4ntxo0y	287	46	spike	spike	NN
cord-293701-u4ntxo0y	287	47	protein	protein	NN
cord-293701-u4ntxo0y	287	48	induces	induce	VBZ
cord-293701-u4ntxo0y	287	49	highly	highly	RB
cord-293701-u4ntxo0y	287	50	potent	potent	JJ
cord-293701-u4ntxo0y	287	51	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	287	52	antibodies	antibody	NNS
cord-293701-u4ntxo0y	287	53	:	:	:
cord-293701-u4ntxo0y	288	1	implication	implication	NN
cord-293701-u4ntxo0y	288	2	for	for	IN
cord-293701-u4ntxo0y	288	3	developing	develop	VBG
cord-293701-u4ntxo0y	288	4	subunit	subunit	JJ
cord-293701-u4ntxo0y	288	5	vaccine	vaccine	NN
cord-293701-u4ntxo0y	288	6	Receptor	receptor	NN
cord-293701-u4ntxo0y	288	7	-	-	HYPH
cord-293701-u4ntxo0y	288	8	binding	bind	VBG
cord-293701-u4ntxo0y	288	9	domain	domain	NN
cord-293701-u4ntxo0y	288	10	of	of	IN
cord-293701-u4ntxo0y	288	11	severe	severe	JJ
cord-293701-u4ntxo0y	288	12	acute	acute	JJ
cord-293701-u4ntxo0y	288	13	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	288	14	syndrome	syndrome	NN
cord-293701-u4ntxo0y	288	15	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	288	16	spike	spike	NN
cord-293701-u4ntxo0y	288	17	protein	protein	NN
cord-293701-u4ntxo0y	288	18	contains	contain	VBZ
cord-293701-u4ntxo0y	288	19	multiple	multiple	JJ
cord-293701-u4ntxo0y	288	20	conformation	conformation	NN
cord-293701-u4ntxo0y	288	21	-	-	HYPH
cord-293701-u4ntxo0y	288	22	dependent	dependent	JJ
cord-293701-u4ntxo0y	288	23	epitopes	epitope	NNS
cord-293701-u4ntxo0y	288	24	that	that	WDT
cord-293701-u4ntxo0y	288	25	induce	induce	VBP
cord-293701-u4ntxo0y	288	26	highly	highly	RB
cord-293701-u4ntxo0y	288	27	potent	potent	JJ
cord-293701-u4ntxo0y	288	28	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	288	29	antibodies	antibody	NNS
cord-293701-u4ntxo0y	289	1	The	the	DT
cord-293701-u4ntxo0y	289	2	spike	spike	NN
cord-293701-u4ntxo0y	289	3	protein	protein	NN
cord-293701-u4ntxo0y	289	4	of	of	IN
cord-293701-u4ntxo0y	289	5	SARS	SARS	NNP
cord-293701-u4ntxo0y	289	6	-	-	HYPH
cord-293701-u4ntxo0y	289	7	CoV	CoV	NNP
cord-293701-u4ntxo0y	289	8	-	-	:
cord-293701-u4ntxo0y	289	9	a	a	DT
cord-293701-u4ntxo0y	289	10	target	target	NN
cord-293701-u4ntxo0y	289	11	for	for	IN
cord-293701-u4ntxo0y	289	12	vaccine	vaccine	NN
cord-293701-u4ntxo0y	289	13	and	and	CC
cord-293701-u4ntxo0y	289	14	therapeutic	therapeutic	JJ
cord-293701-u4ntxo0y	289	15	development	development	NN
cord-293701-u4ntxo0y	289	16	Cross	cross	NN
cord-293701-u4ntxo0y	289	17	-	-	NN
cord-293701-u4ntxo0y	289	18	neutralization	neutralization	NN
cord-293701-u4ntxo0y	289	19	of	of	IN
cord-293701-u4ntxo0y	289	20	human	human	JJ
cord-293701-u4ntxo0y	289	21	and	and	CC
cord-293701-u4ntxo0y	289	22	palm	palm	NN
cord-293701-u4ntxo0y	289	23	civet	civet	NN
cord-293701-u4ntxo0y	289	24	severe	severe	JJ
cord-293701-u4ntxo0y	289	25	acute	acute	JJ
cord-293701-u4ntxo0y	289	26	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	289	27	syndrome	syndrome	NN
cord-293701-u4ntxo0y	289	28	coronaviruses	coronaviruse	NNS
cord-293701-u4ntxo0y	289	29	by	by	IN
cord-293701-u4ntxo0y	289	30	antibodies	antibody	NNS
cord-293701-u4ntxo0y	289	31	targeting	target	VBG
cord-293701-u4ntxo0y	289	32	the	the	DT
cord-293701-u4ntxo0y	289	33	receptor	receptor	NN
cord-293701-u4ntxo0y	289	34	-	-	HYPH
cord-293701-u4ntxo0y	289	35	binding	bind	VBG
cord-293701-u4ntxo0y	289	36	domain	domain	NN
cord-293701-u4ntxo0y	289	37	of	of	IN
cord-293701-u4ntxo0y	289	38	spike	spike	NN
cord-293701-u4ntxo0y	289	39	protein	protein	NN
cord-293701-u4ntxo0y	289	40	SARS	SARS	NNP
cord-293701-u4ntxo0y	289	41	CoV	CoV	NNP
cord-293701-u4ntxo0y	289	42	subunit	subunit	NNP
cord-293701-u4ntxo0y	289	43	vaccine	vaccine	NN
cord-293701-u4ntxo0y	289	44	:	:	:
cord-293701-u4ntxo0y	289	45	antibodymediated	antibodymediated	JJ
cord-293701-u4ntxo0y	289	46	neutralisation	neutralisation	NN
cord-293701-u4ntxo0y	289	47	and	and	CC
cord-293701-u4ntxo0y	289	48	enhancement	enhancement	NN
cord-293701-u4ntxo0y	289	49	Exceptionally	exceptionally	RB
cord-293701-u4ntxo0y	289	50	potent	potent	JJ
cord-293701-u4ntxo0y	289	51	neutralization	neutralization	NN
cord-293701-u4ntxo0y	289	52	of	of	IN
cord-293701-u4ntxo0y	289	53	Middle	Middle	NNP
cord-293701-u4ntxo0y	289	54	East	East	NNP
cord-293701-u4ntxo0y	289	55	respiratory	respiratory	JJ
cord-293701-u4ntxo0y	289	56	syndrome	syndrome	NN
cord-293701-u4ntxo0y	289	57	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	289	58	by	by	IN
cord-293701-u4ntxo0y	289	59	human	human	JJ
cord-293701-u4ntxo0y	289	60	monoclonal	monoclonal	JJ
cord-293701-u4ntxo0y	289	61	antibodies	antibody	NNS
cord-293701-u4ntxo0y	289	62	Neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	289	63	epitopes	epitope	NNS
cord-293701-u4ntxo0y	289	64	of	of	IN
cord-293701-u4ntxo0y	289	65	the	the	DT
cord-293701-u4ntxo0y	289	66	SARS	SARS	NNP
cord-293701-u4ntxo0y	289	67	-	-	HYPH
cord-293701-u4ntxo0y	289	68	CoV	CoV	NNP
cord-293701-u4ntxo0y	289	69	S	S	NNP
cord-293701-u4ntxo0y	289	70	-	-	HYPH
cord-293701-u4ntxo0y	289	71	protein	protein	NN
cord-293701-u4ntxo0y	289	72	cluster	cluster	NN
cord-293701-u4ntxo0y	289	73	independent	independent	JJ
cord-293701-u4ntxo0y	289	74	of	of	IN
cord-293701-u4ntxo0y	289	75	repertoire	repertoire	NN
cord-293701-u4ntxo0y	289	76	,	,	,
cord-293701-u4ntxo0y	289	77	antigen	antigen	NN
cord-293701-u4ntxo0y	289	78	structure	structure	NN
cord-293701-u4ntxo0y	289	79	or	or	CC
cord-293701-u4ntxo0y	289	80	mAb	mab	NN
cord-293701-u4ntxo0y	289	81	technology	technology	NN
cord-293701-u4ntxo0y	290	1	The	the	DT
cord-293701-u4ntxo0y	290	2	SARS	SARS	NNP
cord-293701-u4ntxo0y	290	3	-	-	HYPH
cord-293701-u4ntxo0y	290	4	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	290	5	receptor	receptor	NN
cord-293701-u4ntxo0y	290	6	-	-	HYPH
cord-293701-u4ntxo0y	290	7	binding	bind	VBG
cord-293701-u4ntxo0y	290	8	domain	domain	NN
cord-293701-u4ntxo0y	290	9	elicits	elicit	VBZ
cord-293701-u4ntxo0y	290	10	a	a	DT
cord-293701-u4ntxo0y	290	11	potent	potent	JJ
cord-293701-u4ntxo0y	290	12	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	290	13	response	response	NN
cord-293701-u4ntxo0y	290	14	without	without	IN
cord-293701-u4ntxo0y	290	15	antibody	antibody	NN
cord-293701-u4ntxo0y	290	16	-	-	HYPH
cord-293701-u4ntxo0y	290	17	dependent	dependent	JJ
cord-293701-u4ntxo0y	290	18	enhancement	enhancement	NN
cord-293701-u4ntxo0y	290	19	A	a	DT
cord-293701-u4ntxo0y	290	20	universal	universal	JJ
cord-293701-u4ntxo0y	290	21	design	design	NN
cord-293701-u4ntxo0y	290	22	of	of	IN
cord-293701-u4ntxo0y	290	23	betacoronavirus	betacoronavirus	NN
cord-293701-u4ntxo0y	290	24	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	290	25	against	against	IN
cord-293701-u4ntxo0y	290	26	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	290	27	,	,	,
cord-293701-u4ntxo0y	290	28	MERS	MERS	NNP
cord-293701-u4ntxo0y	290	29	,	,	,
cord-293701-u4ntxo0y	290	30	and	and	CC
cord-293701-u4ntxo0y	290	31	SARS	SARS	NNP
cord-293701-u4ntxo0y	291	1	A	a	DT
cord-293701-u4ntxo0y	291	2	novel	novel	JJ
cord-293701-u4ntxo0y	291	3	receptor	receptor	NN
cord-293701-u4ntxo0y	291	4	-	-	HYPH
cord-293701-u4ntxo0y	291	5	binding	bind	VBG
cord-293701-u4ntxo0y	291	6	domain	domain	NN
cord-293701-u4ntxo0y	291	7	(	(	-LRB-
cord-293701-u4ntxo0y	291	8	RBD)-based	rbd)-base	VBN
cord-293701-u4ntxo0y	291	9	mRNA	mrna	NN
cord-293701-u4ntxo0y	291	10	vaccine	vaccine	NN
cord-293701-u4ntxo0y	291	11	against	against	IN
cord-293701-u4ntxo0y	291	12	SARS	SARS	NNP
cord-293701-u4ntxo0y	291	13	-	-	HYPH
cord-293701-u4ntxo0y	291	14	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	292	1	A	a	DT
cord-293701-u4ntxo0y	292	2	thermostable	thermostable	JJ
cord-293701-u4ntxo0y	292	3	mRNA	mRNA	NNP
cord-293701-u4ntxo0y	292	4	vaccine	vaccine	NN
cord-293701-u4ntxo0y	292	5	against	against	IN
cord-293701-u4ntxo0y	292	6	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	292	7	Broad	Broad	NNP
cord-293701-u4ntxo0y	292	8	neutralization	neutralization	NN
cord-293701-u4ntxo0y	292	9	of	of	IN
cord-293701-u4ntxo0y	292	10	SARS	SARS	NNP
cord-293701-u4ntxo0y	292	11	-	-	HYPH
cord-293701-u4ntxo0y	292	12	related	relate	VBN
cord-293701-u4ntxo0y	292	13	viruses	virus	NNS
cord-293701-u4ntxo0y	292	14	by	by	IN
cord-293701-u4ntxo0y	292	15	human	human	JJ
cord-293701-u4ntxo0y	292	16	monoclonal	monoclonal	JJ
cord-293701-u4ntxo0y	292	17	antibodies	antibody	NNS
cord-293701-u4ntxo0y	292	18	Cross	Cross	NNP
cord-293701-u4ntxo0y	292	19	-	-	NN
cord-293701-u4ntxo0y	292	20	neutralization	neutralization	NN
cord-293701-u4ntxo0y	292	21	of	of	IN
cord-293701-u4ntxo0y	292	22	SARS	SARS	NNP
cord-293701-u4ntxo0y	292	23	-	-	HYPH
cord-293701-u4ntxo0y	292	24	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	292	25	by	by	IN
cord-293701-u4ntxo0y	292	26	a	a	DT
cord-293701-u4ntxo0y	292	27	human	human	JJ
cord-293701-u4ntxo0y	292	28	monoclonal	monoclonal	JJ
cord-293701-u4ntxo0y	292	29	SARS	SARS	NNP
cord-293701-u4ntxo0y	292	30	-	-	HYPH
cord-293701-u4ntxo0y	292	31	CoV	CoV	NNP
cord-293701-u4ntxo0y	292	32	antibody	antibody	NN
cord-293701-u4ntxo0y	292	33	Cross	Cross	NNP
cord-293701-u4ntxo0y	292	34	-	-	JJ
cord-293701-u4ntxo0y	292	35	reactive	reactive	JJ
cord-293701-u4ntxo0y	292	36	neutralization	neutralization	NN
cord-293701-u4ntxo0y	292	37	of	of	IN
cord-293701-u4ntxo0y	292	38	SARS	SARS	NNP
cord-293701-u4ntxo0y	292	39	-	-	HYPH
cord-293701-u4ntxo0y	292	40	CoV-2	CoV-2	NNP
cord-293701-u4ntxo0y	292	41	by	by	IN
cord-293701-u4ntxo0y	292	42	serum	serum	NN
cord-293701-u4ntxo0y	292	43	antibodies	antibody	NNS
cord-293701-u4ntxo0y	292	44	from	from	IN
cord-293701-u4ntxo0y	292	45	recovered	recover	VBN
cord-293701-u4ntxo0y	292	46	SARS	SARS	NNP
cord-293701-u4ntxo0y	292	47	patients	patient	NNS
cord-293701-u4ntxo0y	292	48	and	and	CC
cord-293701-u4ntxo0y	292	49	immunized	immunize	VBN
cord-293701-u4ntxo0y	292	50	animals	animal	NNS
cord-293701-u4ntxo0y	293	1	Introduction	introduction	NN
cord-293701-u4ntxo0y	293	2	of	of	IN
cord-293701-u4ntxo0y	293	3	neutralizing	neutralize	VBG
cord-293701-u4ntxo0y	293	4	immunogenicity	immunogenicity	NN
cord-293701-u4ntxo0y	293	5	index	index	NN
cord-293701-u4ntxo0y	293	6	to	to	IN
cord-293701-u4ntxo0y	293	7	the	the	DT
cord-293701-u4ntxo0y	293	8	rational	rational	JJ
cord-293701-u4ntxo0y	293	9	design	design	NN
cord-293701-u4ntxo0y	293	10	of	of	IN
cord-293701-u4ntxo0y	293	11	MERS	MERS	NNP
cord-293701-u4ntxo0y	293	12	coronavirus	coronavirus	NN
cord-293701-u4ntxo0y	293	13	subunit	subunit	NN
cord-293701-u4ntxo0y	293	14	vaccines	vaccine	NNS
cord-293701-u4ntxo0y	293	15	Yeast	yeast	NN
cord-293701-u4ntxo0y	293	16	-	-	HYPH
cord-293701-u4ntxo0y	293	17	expressed	express	VBN
cord-293701-u4ntxo0y	293	18	recombinant	recombinant	JJ
cord-293701-u4ntxo0y	293	19	protein	protein	NN
cord-293701-u4ntxo0y	293	20	of	of	IN
cord-293701-u4ntxo0y	293	21	the	the	DT
cord-293701-u4ntxo0y	293	22	receptor	receptor	NN
cord-293701-u4ntxo0y	293	23	-	-	HYPH
cord-293701-u4ntxo0y	293	24	binding	bind	VBG
cord-293701-u4ntxo0y	293	25	domain	domain	NN
cord-293701-u4ntxo0y	293	26	in	in	IN
cord-293701-u4ntxo0y	293	27	SARS	SARS	NNP
cord-293701-u4ntxo0y	293	28	-	-	HYPH
cord-293701-u4ntxo0y	293	29	CoV	CoV	NNP
cord-293701-u4ntxo0y	293	30	spike	spike	NN
cord-293701-u4ntxo0y	293	31	protein	protein	NN
cord-293701-u4ntxo0y	293	32	with	with	IN
cord-293701-u4ntxo0y	293	33	deglycosylated	deglycosylated	JJ
cord-293701-u4ntxo0y	293	34	forms	form	NNS
cord-293701-u4ntxo0y	293	35	as	as	IN
cord-293701-u4ntxo0y	293	36	a	a	DT
cord-293701-u4ntxo0y	293	37	SARS	SARS	NNP
cord-293701-u4ntxo0y	293	38	vaccine	vaccine	NN
cord-293701-u4ntxo0y	293	39	candidate	candidate	NN
cord-293701-u4ntxo0y	293	40	More	More	JJR
cord-293701-u4ntxo0y	293	41	than	than	IN
cord-293701-u4ntxo0y	293	42	150	150	CD
cord-293701-u4ntxo0y	293	43	countries	country	NNS
cord-293701-u4ntxo0y	293	44	engaged	engage	VBN
cord-293701-u4ntxo0y	293	45	in	in	IN
cord-293701-u4ntxo0y	293	46	COVID-19	COVID-19	NNP
cord-293701-u4ntxo0y	293	47	vaccine	vaccine	NN
cord-293701-u4ntxo0y	293	48	global	global	JJ
cord-293701-u4ntxo0y	293	49	access	access	NN
cord-293701-u4ntxo0y	293	50	facility	facility	NN
cord-293701-u4ntxo0y	294	1	The	the	DT
cord-293701-u4ntxo0y	294	2	authors	author	NNS
cord-293701-u4ntxo0y	294	3	thank	thank	VBP
cord-293701-u4ntxo0y	294	4	L.	L.	NNP
cord-293701-u4ntxo0y	294	5	Lu	Lu	NNP
cord-293701-u4ntxo0y	294	6	at	at	IN
cord-293701-u4ntxo0y	294	7	the	the	DT
cord-293701-u4ntxo0y	294	8	School	School	NNP
cord-293701-u4ntxo0y	294	9	of	of	IN
cord-293701-u4ntxo0y	294	10	Basic	Basic	NNP
cord-293701-u4ntxo0y	294	11	Medical	Medical	NNP
cord-293701-u4ntxo0y	294	12	Sciences	Sciences	NNPS
cord-293701-u4ntxo0y	294	13	,	,	,
cord-293701-u4ntxo0y	294	14	Fudan	Fudan	NNP
cord-293701-u4ntxo0y	294	15	University	University	NNP
cord-293701-u4ntxo0y	294	16	,	,	,
cord-293701-u4ntxo0y	294	17	for	for	IN
cord-293701-u4ntxo0y	294	18	providing	provide	VBG
cord-293701-u4ntxo0y	294	19	his	-PRON-	PRP$
cord-293701-u4ntxo0y	294	20	valuable	valuable	JJ
cord-293701-u4ntxo0y	294	21	comments	comment	NNS
cord-293701-u4ntxo0y	294	22	and	and	CC
cord-293701-u4ntxo0y	294	23	suggestions	suggestion	NNS
cord-293701-u4ntxo0y	294	24	to	to	TO
cord-293701-u4ntxo0y	294	25	improve	improve	VB
cord-293701-u4ntxo0y	294	26	the	the	DT
cord-293701-u4ntxo0y	294	27	manuscript	manuscript	NN
cord-293701-u4ntxo0y	294	28	.	.	.
cord-293701-u4ntxo0y	295	1	S.J.	S.J.	NNP
cord-293701-u4ntxo0y	295	2	contributed	contribute	VBD
cord-293701-u4ntxo0y	295	3	to	to	IN
cord-293701-u4ntxo0y	295	4	discussion	discussion	NN
cord-293701-u4ntxo0y	295	5	of	of	IN
cord-293701-u4ntxo0y	295	6	the	the	DT
cord-293701-u4ntxo0y	295	7	content	content	NN
cord-293701-u4ntxo0y	295	8	,	,	,
cord-293701-u4ntxo0y	295	9	S.S.	S.S.	NNP
cord-293701-u4ntxo0y	295	10	wrote	write	VBD
cord-293701-u4ntxo0y	295	11	the	the	DT
cord-293701-u4ntxo0y	295	12	article	article	NN
cord-293701-u4ntxo0y	295	13	and	and	CC
cord-293701-u4ntxo0y	295	14	L.D.	L.D.	NNP
cord-293701-u4ntxo0y	295	15	and	and	CC
cord-293701-u4ntxo0y	295	16	S.J.	S.J.	NNP
cord-293701-u4ntxo0y	295	17	reviewed	review	VBD
cord-293701-u4ntxo0y	295	18	and	and	CC
cord-293701-u4ntxo0y	295	19	edited	edit	VBD
cord-293701-u4ntxo0y	295	20	the	the	DT
cord-293701-u4ntxo0y	295	21	manuscript	manuscript	NN
cord-293701-u4ntxo0y	295	22	before	before	IN
cord-293701-u4ntxo0y	295	23	submission	submission	NN
cord-293701-u4ntxo0y	295	24	.	.	.
cord-293701-u4ntxo0y	296	1	The	the	DT
cord-293701-u4ntxo0y	296	2	authors	author	NNS
cord-293701-u4ntxo0y	296	3	declare	declare	VBP
cord-293701-u4ntxo0y	296	4	no	no	DT
cord-293701-u4ntxo0y	296	5	competing	compete	VBG
cord-293701-u4ntxo0y	296	6	interests	interest	NNS
cord-293701-u4ntxo0y	296	7	.	.	.
cord-293701-u4ntxo0y	297	1	Nature	Nature	NNP
cord-293701-u4ntxo0y	297	2	Reviews	Reviews	NNPS
cord-293701-u4ntxo0y	297	3	Microbiology	Microbiology	NNP
cord-293701-u4ntxo0y	297	4	thanks	thank	NNS
cord-293701-u4ntxo0y	297	5	Akiko	Akiko	NNP
cord-293701-u4ntxo0y	297	6	Iwasaki	Iwasaki	NNP
cord-293701-u4ntxo0y	297	7	,	,	,
cord-293701-u4ntxo0y	297	8	Vincent	Vincent	NNP
cord-293701-u4ntxo0y	297	9	Munster	Munster	NNP
cord-293701-u4ntxo0y	297	10	,	,	,
cord-293701-u4ntxo0y	297	11	and	and	CC
cord-293701-u4ntxo0y	297	12	the	the	DT
cord-293701-u4ntxo0y	297	13	other	other	JJ
cord-293701-u4ntxo0y	297	14	,	,	,
cord-293701-u4ntxo0y	297	15	anonymous	anonymous	JJ
cord-293701-u4ntxo0y	297	16	,	,	,
cord-293701-u4ntxo0y	297	17	reviewer(s	reviewer(s	NNP
cord-293701-u4ntxo0y	297	18	)	)	-RRB-
cord-293701-u4ntxo0y	297	19	for	for	IN
cord-293701-u4ntxo0y	297	20	their	-PRON-	PRP$
cord-293701-u4ntxo0y	297	21	contribution	contribution	NN
cord-293701-u4ntxo0y	297	22	to	to	IN
cord-293701-u4ntxo0y	297	23	the	the	DT
cord-293701-u4ntxo0y	297	24	peer	peer	NN
cord-293701-u4ntxo0y	297	25	review	review	NN
cord-293701-u4ntxo0y	297	26	of	of	IN
cord-293701-u4ntxo0y	297	27	this	this	DT
cord-293701-u4ntxo0y	297	28	work	work	NN
cord-293701-u4ntxo0y	297	29	.	.	.