id	sid	tid	token	lemma	pos
cord-258708-da6x5rxa	1	1	key	key	NN
cord-258708-da6x5rxa	1	2	:	:	:
cord-258708-da6x5rxa	1	3	cord-258708-da6x5rxa	cord-258708-da6x5rxa	NNP
cord-258708-da6x5rxa	1	4	authors	author	NNS
cord-258708-da6x5rxa	1	5	:	:	:
cord-258708-da6x5rxa	1	6	Hafiane	Hafiane	NNP
cord-258708-da6x5rxa	1	7	,	,	,
cord-258708-da6x5rxa	1	8	Anouar	Anouar	NNP
cord-258708-da6x5rxa	1	9	title	title	NN
cord-258708-da6x5rxa	1	10	:	:	:
cord-258708-da6x5rxa	1	11	SARS	SARS	NNP
cord-258708-da6x5rxa	1	12	-	-	HYPH
cord-258708-da6x5rxa	1	13	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	1	14	and	and	CC
cord-258708-da6x5rxa	1	15	the	the	DT
cord-258708-da6x5rxa	1	16	cardiovascular	cardiovascular	JJ
cord-258708-da6x5rxa	1	17	system	system	NN
cord-258708-da6x5rxa	1	18	date	date	NN
cord-258708-da6x5rxa	1	19	:	:	:
cord-258708-da6x5rxa	1	20	2020	2020	CD
cord-258708-da6x5rxa	1	21	-	-	HYPH
cord-258708-da6x5rxa	1	22	07	07	CD
cord-258708-da6x5rxa	1	23	-	-	HYPH
cord-258708-da6x5rxa	1	24	16	16	CD
cord-258708-da6x5rxa	1	25	journal	journal	NN
cord-258708-da6x5rxa	1	26	:	:	:
cord-258708-da6x5rxa	2	1	Clin	Clin	NNP
cord-258708-da6x5rxa	2	2	Chim	Chim	NNP
cord-258708-da6x5rxa	2	3	Acta	Acta	NNP
cord-258708-da6x5rxa	3	1	DOI	DOI	NNP
cord-258708-da6x5rxa	3	2	:	:	:
cord-258708-da6x5rxa	3	3	10.1016	10.1016	CD
cord-258708-da6x5rxa	3	4	/	/	SYM
cord-258708-da6x5rxa	3	5	j.cca.2020.07.019	j.cca.2020.07.019	NNP
cord-258708-da6x5rxa	3	6	sha	sha	NNP
cord-258708-da6x5rxa	3	7	:	:	:
cord-258708-da6x5rxa	3	8	727e0aa038b84bda7da4c96f6f813ec7622300e8	727e0aa038b84bda7da4c96f6f813ec7622300e8	CD
cord-258708-da6x5rxa	3	9	doc_id	doc_id	CD
cord-258708-da6x5rxa	3	10	:	:	:
cord-258708-da6x5rxa	3	11	258708	258708	CD
cord-258708-da6x5rxa	3	12	cord_uid	cord_uid	NNS
cord-258708-da6x5rxa	3	13	:	:	:
cord-258708-da6x5rxa	4	1	da6x5rxa	da6x5rxa	NNP
cord-258708-da6x5rxa	5	1	The	the	DT
cord-258708-da6x5rxa	5	2	coronavirus	coronavirus	NN
cord-258708-da6x5rxa	5	3	disease	disease	NN
cord-258708-da6x5rxa	5	4	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	5	5	is	be	VBZ
cord-258708-da6x5rxa	5	6	a	a	DT
cord-258708-da6x5rxa	5	7	public	public	JJ
cord-258708-da6x5rxa	5	8	health	health	NN
cord-258708-da6x5rxa	5	9	emergency	emergency	NN
cord-258708-da6x5rxa	5	10	caused	cause	VBN
cord-258708-da6x5rxa	5	11	by	by	IN
cord-258708-da6x5rxa	5	12	a	a	DT
cord-258708-da6x5rxa	5	13	novel	novel	JJ
cord-258708-da6x5rxa	5	14	coronavirus	coronavirus	NN
cord-258708-da6x5rxa	5	15	named	name	VBN
cord-258708-da6x5rxa	5	16	severe	severe	JJ
cord-258708-da6x5rxa	5	17	acute	acute	JJ
cord-258708-da6x5rxa	5	18	respiratory	respiratory	JJ
cord-258708-da6x5rxa	5	19	syndrome	syndrome	NN
cord-258708-da6x5rxa	5	20	coronavirus-2	coronavirus-2	NNP
cord-258708-da6x5rxa	5	21	(	(	-LRB-
cord-258708-da6x5rxa	5	22	SARS	SARS	NNP
cord-258708-da6x5rxa	5	23	-	-	HYPH
cord-258708-da6x5rxa	5	24	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	5	25	)	)	-RRB-
cord-258708-da6x5rxa	5	26	.	.	.
cord-258708-da6x5rxa	6	1	SARS	SARS	NNP
cord-258708-da6x5rxa	6	2	-	-	HYPH
cord-258708-da6x5rxa	6	3	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	6	4	infection	infection	NN
cord-258708-da6x5rxa	6	5	uses	use	VBZ
cord-258708-da6x5rxa	6	6	the	the	DT
cord-258708-da6x5rxa	6	7	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	6	8	-	-	HYPH
cord-258708-da6x5rxa	6	9	converting	convert	VBG
cord-258708-da6x5rxa	6	10	enzyme	enzyme	NN
cord-258708-da6x5rxa	6	11	2	2	CD
cord-258708-da6x5rxa	6	12	(	(	-LRB-
cord-258708-da6x5rxa	6	13	ACE2	ACE2	NNP
cord-258708-da6x5rxa	6	14	)	)	-RRB-
cord-258708-da6x5rxa	6	15	receptor	receptor	NN
cord-258708-da6x5rxa	6	16	,	,	,
cord-258708-da6x5rxa	6	17	and	and	CC
cord-258708-da6x5rxa	6	18	typically	typically	RB
cord-258708-da6x5rxa	6	19	spreads	spread	VBZ
cord-258708-da6x5rxa	6	20	through	through	IN
cord-258708-da6x5rxa	6	21	the	the	DT
cord-258708-da6x5rxa	6	22	respiratory	respiratory	JJ
cord-258708-da6x5rxa	6	23	tract	tract	NN
cord-258708-da6x5rxa	6	24	.	.	.
cord-258708-da6x5rxa	7	1	Invading	invade	VBG
cord-258708-da6x5rxa	7	2	viruses	virus	NNS
cord-258708-da6x5rxa	7	3	can	can	MD
cord-258708-da6x5rxa	7	4	elicit	elicit	VB
cord-258708-da6x5rxa	7	5	an	an	DT
cord-258708-da6x5rxa	7	6	exaggerated	exaggerated	JJ
cord-258708-da6x5rxa	7	7	host	host	NN
cord-258708-da6x5rxa	7	8	immune	immune	JJ
cord-258708-da6x5rxa	7	9	response	response	NN
cord-258708-da6x5rxa	7	10	,	,	,
cord-258708-da6x5rxa	7	11	frequently	frequently	RB
cord-258708-da6x5rxa	7	12	leading	lead	VBG
cord-258708-da6x5rxa	7	13	to	to	IN
cord-258708-da6x5rxa	7	14	a	a	DT
cord-258708-da6x5rxa	7	15	cytokine	cytokine	NN
cord-258708-da6x5rxa	7	16	storm	storm	NN
cord-258708-da6x5rxa	7	17	that	that	WDT
cord-258708-da6x5rxa	7	18	may	may	MD
cord-258708-da6x5rxa	7	19	be	be	VB
cord-258708-da6x5rxa	7	20	fueling	fuel	VBG
cord-258708-da6x5rxa	7	21	some	some	DT
cord-258708-da6x5rxa	7	22	COVID-19	covid-19	CD
cord-258708-da6x5rxa	7	23	death	death	NN
cord-258708-da6x5rxa	7	24	.	.	.
cord-258708-da6x5rxa	8	1	This	this	DT
cord-258708-da6x5rxa	8	2	response	response	NN
cord-258708-da6x5rxa	8	3	contributes	contribute	VBZ
cord-258708-da6x5rxa	8	4	to	to	IN
cord-258708-da6x5rxa	8	5	multi	multi	JJ
cord-258708-da6x5rxa	8	6	-	-	JJ
cord-258708-da6x5rxa	8	7	organ	organ	JJ
cord-258708-da6x5rxa	8	8	dysfunction	dysfunction	NN
cord-258708-da6x5rxa	8	9	.	.	.
cord-258708-da6x5rxa	9	1	Accumulating	accumulate	VBG
cord-258708-da6x5rxa	9	2	data	data	NN
cord-258708-da6x5rxa	9	3	points	point	NNS
cord-258708-da6x5rxa	9	4	to	to	IN
cord-258708-da6x5rxa	9	5	an	an	DT
cord-258708-da6x5rxa	9	6	increased	increase	VBN
cord-258708-da6x5rxa	9	7	cardiovascular	cardiovascular	JJ
cord-258708-da6x5rxa	9	8	disease	disease	NN
cord-258708-da6x5rxa	9	9	morbidity	morbidity	NN
cord-258708-da6x5rxa	9	10	,	,	,
cord-258708-da6x5rxa	9	11	and	and	CC
cord-258708-da6x5rxa	9	12	mortality	mortality	NN
cord-258708-da6x5rxa	9	13	in	in	IN
cord-258708-da6x5rxa	9	14	COVID-19	covid-19	JJ
cord-258708-da6x5rxa	9	15	patients	patient	NNS
cord-258708-da6x5rxa	9	16	.	.	.
cord-258708-da6x5rxa	10	1	This	this	DT
cord-258708-da6x5rxa	10	2	brief	brief	JJ
cord-258708-da6x5rxa	10	3	review	review	NN
cord-258708-da6x5rxa	10	4	explores	explore	VBZ
cord-258708-da6x5rxa	10	5	potential	potential	JJ
cord-258708-da6x5rxa	10	6	available	available	JJ
cord-258708-da6x5rxa	10	7	evidence	evidence	NN
cord-258708-da6x5rxa	10	8	regarding	regard	VBG
cord-258708-da6x5rxa	10	9	the	the	DT
cord-258708-da6x5rxa	10	10	association	association	NN
cord-258708-da6x5rxa	10	11	between	between	IN
cord-258708-da6x5rxa	10	12	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	10	13	,	,	,
cord-258708-da6x5rxa	10	14	and	and	CC
cord-258708-da6x5rxa	10	15	cardiovascular	cardiovascular	JJ
cord-258708-da6x5rxa	10	16	complications	complication	NNS
cord-258708-da6x5rxa	10	17	.	.	.
cord-258708-da6x5rxa	11	1	Epidemic	Epidemic	NNP
cord-258708-da6x5rxa	11	2	Corona	Corona	NNP
cord-258708-da6x5rxa	11	3	Virus	Virus	NNP
cord-258708-da6x5rxa	11	4	Disease	Disease	NNP
cord-258708-da6x5rxa	11	5	2019	2019	CD
cord-258708-da6x5rxa	12	1	(	(	-LRB-
cord-258708-da6x5rxa	12	2	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	12	3	)	)	-RRB-
cord-258708-da6x5rxa	12	4	is	be	VBZ
cord-258708-da6x5rxa	12	5	gradually	gradually	RB
cord-258708-da6x5rxa	12	6	spreading	spread	VBG
cord-258708-da6x5rxa	12	7	by	by	IN
cord-258708-da6x5rxa	12	8	human	human	NN
cord-258708-da6x5rxa	12	9	-	-	HYPH
cord-258708-da6x5rxa	12	10	to	to	IN
cord-258708-da6x5rxa	12	11	-	-	HYPH
cord-258708-da6x5rxa	12	12	human	human	JJ
cord-258708-da6x5rxa	12	13	transmission	transmission	NN
cord-258708-da6x5rxa	12	14	.	.	.
cord-258708-da6x5rxa	13	1	The	the	DT
cord-258708-da6x5rxa	13	2	pathogen	pathogen	NN
cord-258708-da6x5rxa	13	3	has	have	VBZ
cord-258708-da6x5rxa	13	4	been	be	VBN
cord-258708-da6x5rxa	13	5	named	name	VBN
cord-258708-da6x5rxa	13	6	severe	severe	JJ
cord-258708-da6x5rxa	13	7	acute	acute	JJ
cord-258708-da6x5rxa	13	8	respiratory	respiratory	JJ
cord-258708-da6x5rxa	13	9	syndrome	syndrome	NN
cord-258708-da6x5rxa	13	10	coronavirus	coronavirus	NN
cord-258708-da6x5rxa	13	11	2	2	CD
cord-258708-da6x5rxa	14	1	(	(	-LRB-
cord-258708-da6x5rxa	14	2	SARS	SARS	NNP
cord-258708-da6x5rxa	14	3	-	-	HYPH
cord-258708-da6x5rxa	14	4	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	14	5	)	)	-RRB-
cord-258708-da6x5rxa	14	6	(	(	-LRB-
cord-258708-da6x5rxa	14	7	1	1	CD
cord-258708-da6x5rxa	14	8	,	,	,
cord-258708-da6x5rxa	14	9	2	2	CD
cord-258708-da6x5rxa	14	10	)	)	-RRB-
cord-258708-da6x5rxa	14	11	.	.	.
cord-258708-da6x5rxa	15	1	In	in	IN
cord-258708-da6x5rxa	15	2	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	15	3	,	,	,
cord-258708-da6x5rxa	15	4	particular	particular	JJ
cord-258708-da6x5rxa	15	5	attention	attention	NN
cord-258708-da6x5rxa	15	6	has	have	VBZ
cord-258708-da6x5rxa	15	7	been	be	VBN
cord-258708-da6x5rxa	15	8	given	give	VBN
cord-258708-da6x5rxa	15	9	to	to	IN
cord-258708-da6x5rxa	15	10	the	the	DT
cord-258708-da6x5rxa	15	11	role	role	NN
cord-258708-da6x5rxa	15	12	of	of	IN
cord-258708-da6x5rxa	15	13	angiotensin-(Ang	angiotensin-(ang	CD
cord-258708-da6x5rxa	15	14	)	)	-RRB-
cord-258708-da6x5rxa	15	15	converting	convert	VBG
cord-258708-da6x5rxa	15	16	enzyme	enzyme	NN
cord-258708-da6x5rxa	15	17	2	2	CD
cord-258708-da6x5rxa	15	18	(	(	-LRB-
cord-258708-da6x5rxa	15	19	ACE2	ACE2	NNP
cord-258708-da6x5rxa	15	20	)	)	-RRB-
cord-258708-da6x5rxa	15	21	,	,	,
cord-258708-da6x5rxa	15	22	and	and	CC
cord-258708-da6x5rxa	15	23	the	the	DT
cord-258708-da6x5rxa	15	24	binding	binding	NN
cord-258708-da6x5rxa	15	25	site	site	NN
cord-258708-da6x5rxa	15	26	for	for	IN
cord-258708-da6x5rxa	15	27	SARS	SARS	NNP
cord-258708-da6x5rxa	15	28	-	-	HYPH
cord-258708-da6x5rxa	15	29	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	15	30	cellular	cellular	JJ
cord-258708-da6x5rxa	15	31	entry	entry	NN
cord-258708-da6x5rxa	15	32	(	(	-LRB-
cord-258708-da6x5rxa	15	33	3	3	CD
cord-258708-da6x5rxa	15	34	)	)	-RRB-
cord-258708-da6x5rxa	15	35	.	.	.
cord-258708-da6x5rxa	16	1	Besides	besides	IN
cord-258708-da6x5rxa	16	2	severe	severe	JJ
cord-258708-da6x5rxa	16	3	lung	lung	NN
cord-258708-da6x5rxa	16	4	involvement	involvement	NN
cord-258708-da6x5rxa	16	5	,	,	,
cord-258708-da6x5rxa	16	6	invasion	invasion	NN
cord-258708-da6x5rxa	16	7	of	of	IN
cord-258708-da6x5rxa	16	8	the	the	DT
cord-258708-da6x5rxa	16	9	virus	virus	NN
cord-258708-da6x5rxa	16	10	into	into	IN
cord-258708-da6x5rxa	16	11	circulation	circulation	NN
cord-258708-da6x5rxa	16	12	elicits	elicit	VBZ
cord-258708-da6x5rxa	16	13	an	an	DT
cord-258708-da6x5rxa	16	14	exaggerated	exaggerated	JJ
cord-258708-da6x5rxa	16	15	host	host	NN
cord-258708-da6x5rxa	16	16	immune	immune	JJ
cord-258708-da6x5rxa	16	17	response	response	NN
cord-258708-da6x5rxa	16	18	,	,	,
cord-258708-da6x5rxa	16	19	frequently	frequently	RB
cord-258708-da6x5rxa	16	20	leading	lead	VBG
cord-258708-da6x5rxa	16	21	to	to	IN
cord-258708-da6x5rxa	16	22	a	a	DT
cord-258708-da6x5rxa	16	23	cytokine	cytokine	NN
cord-258708-da6x5rxa	16	24	storm	storm	NN
cord-258708-da6x5rxa	16	25	that	that	WDT
cord-258708-da6x5rxa	16	26	is	be	VBZ
cord-258708-da6x5rxa	16	27	associated	associate	VBN
cord-258708-da6x5rxa	16	28	with	with	IN
cord-258708-da6x5rxa	16	29	in	in	IN
cord-258708-da6x5rxa	16	30	-	-	HYPH
cord-258708-da6x5rxa	16	31	hospital	hospital	NN
cord-258708-da6x5rxa	16	32	death	death	NN
cord-258708-da6x5rxa	16	33	(	(	-LRB-
cord-258708-da6x5rxa	16	34	4	4	CD
cord-258708-da6x5rxa	16	35	)	)	-RRB-
cord-258708-da6x5rxa	16	36	.	.	.
cord-258708-da6x5rxa	17	1	At	at	IN
cord-258708-da6x5rxa	17	2	present	present	JJ
cord-258708-da6x5rxa	17	3	,	,	,
cord-258708-da6x5rxa	17	4	there	there	EX
cord-258708-da6x5rxa	17	5	are	be	VBP
cord-258708-da6x5rxa	17	6	very	very	RB
cord-258708-da6x5rxa	17	7	few	few	JJ
cord-258708-da6x5rxa	17	8	evidences	evidence	NNS
cord-258708-da6x5rxa	17	9	supporting	support	VBG
cord-258708-da6x5rxa	17	10	cardiac	cardiac	JJ
cord-258708-da6x5rxa	17	11	involvement	involvement	NN
cord-258708-da6x5rxa	17	12	during	during	IN
cord-258708-da6x5rxa	17	13	SARS	SARS	NNP
cord-258708-da6x5rxa	17	14	-	-	HYPH
cord-258708-da6x5rxa	17	15	Cov-2	Cov-2	NNP
cord-258708-da6x5rxa	17	16	infection	infection	NN
cord-258708-da6x5rxa	17	17	,	,	,
cord-258708-da6x5rxa	17	18	and	and	CC
cord-258708-da6x5rxa	17	19	they	-PRON-	PRP
cord-258708-da6x5rxa	17	20	arose	arise	VBD
cord-258708-da6x5rxa	17	21	mainly	mainly	RB
cord-258708-da6x5rxa	17	22	from	from	IN
cord-258708-da6x5rxa	17	23	observational	observational	JJ
cord-258708-da6x5rxa	17	24	studies	study	NNS
cord-258708-da6x5rxa	17	25	.	.	.
cord-258708-da6x5rxa	18	1	Accumulating	accumulate	VBG
cord-258708-da6x5rxa	18	2	data	data	NN
cord-258708-da6x5rxa	18	3	points	point	NNS
cord-258708-da6x5rxa	18	4	to	to	IN
cord-258708-da6x5rxa	18	5	the	the	DT
cord-258708-da6x5rxa	18	6	implication	implication	NN
cord-258708-da6x5rxa	18	7	of	of	IN
cord-258708-da6x5rxa	18	8	the	the	DT
cord-258708-da6x5rxa	18	9	cardiovascular	cardiovascular	NN
cord-258708-da6x5rxa	18	10	(	(	-LRB-
cord-258708-da6x5rxa	18	11	CV	cv	NN
cord-258708-da6x5rxa	18	12	)	)	-RRB-
cord-258708-da6x5rxa	18	13	system	system	NN
cord-258708-da6x5rxa	18	14	on	on	IN
cord-258708-da6x5rxa	18	15	multiple	multiple	JJ
cord-258708-da6x5rxa	18	16	levels	level	NNS
cord-258708-da6x5rxa	18	17	linking	link	VBG
cord-258708-da6x5rxa	18	18	COVID-19	covid-19	CD
cord-258708-da6x5rxa	18	19	with	with	IN
cord-258708-da6x5rxa	18	20	increased	increase	VBN
cord-258708-da6x5rxa	18	21	morbidity	morbidity	NN
cord-258708-da6x5rxa	18	22	,	,	,
cord-258708-da6x5rxa	18	23	and	and	CC
cord-258708-da6x5rxa	18	24	mortality	mortality	NN
cord-258708-da6x5rxa	18	25	from	from	IN
cord-258708-da6x5rxa	18	26	cardiovascular	cardiovascular	JJ
cord-258708-da6x5rxa	18	27	disease	disease	NN
cord-258708-da6x5rxa	18	28	(	(	-LRB-
cord-258708-da6x5rxa	18	29	CVD	CVD	NNP
cord-258708-da6x5rxa	18	30	)	)	-RRB-
cord-258708-da6x5rxa	18	31	.	.	.
cord-258708-da6x5rxa	19	1	In	in	IN
cord-258708-da6x5rxa	19	2	this	this	DT
cord-258708-da6x5rxa	19	3	review	review	NN
cord-258708-da6x5rxa	19	4	article	article	NN
cord-258708-da6x5rxa	19	5	,	,	,
cord-258708-da6x5rxa	19	6	we	-PRON-	PRP
cord-258708-da6x5rxa	19	7	explore	explore	VBP
cord-258708-da6x5rxa	19	8	SARS	SARS	NNP
cord-258708-da6x5rxa	19	9	-	-	HYPH
cord-258708-da6x5rxa	19	10	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	19	11	associated	associate	VBN
cord-258708-da6x5rxa	19	12	infection	infection	NN
cord-258708-da6x5rxa	19	13	mechanisms	mechanism	NNS
cord-258708-da6x5rxa	19	14	with	with	IN
cord-258708-da6x5rxa	19	15	a	a	DT
cord-258708-da6x5rxa	19	16	special	special	JJ
cord-258708-da6x5rxa	19	17	focus	focus	NN
cord-258708-da6x5rxa	19	18	on	on	IN
cord-258708-da6x5rxa	19	19	CVD	CVD	NNP
cord-258708-da6x5rxa	19	20	and	and	CC
cord-258708-da6x5rxa	19	21	provide	provide	VB
cord-258708-da6x5rxa	19	22	an	an	DT
cord-258708-da6x5rxa	19	23	overview	overview	NN
cord-258708-da6x5rxa	19	24	of	of	IN
cord-258708-da6x5rxa	19	25	this	this	DT
cord-258708-da6x5rxa	19	26	topic	topic	NN
cord-258708-da6x5rxa	19	27	.	.	.
cord-258708-da6x5rxa	20	1	Corona	corona	NN
cord-258708-da6x5rxa	20	2	viruses	virus	NNS
cord-258708-da6x5rxa	20	3	are	be	VBP
cord-258708-da6x5rxa	20	4	miniature	miniature	JJ
cord-258708-da6x5rxa	20	5	in	in	IN
cord-258708-da6x5rxa	20	6	size	size	NN
cord-258708-da6x5rxa	20	7	(	(	-LRB-
cord-258708-da6x5rxa	20	8	60	60	CD
cord-258708-da6x5rxa	20	9	-	-	SYM
cord-258708-da6x5rxa	20	10	140	140	CD
cord-258708-da6x5rxa	20	11	nm	nm	NN
cord-258708-da6x5rxa	20	12	in	in	IN
cord-258708-da6x5rxa	20	13	diameter	diameter	NN
cord-258708-da6x5rxa	20	14	)	)	-RRB-
cord-258708-da6x5rxa	20	15	and	and	CC
cord-258708-da6x5rxa	20	16	contain	contain	VBP
cord-258708-da6x5rxa	20	17	a	a	DT
cord-258708-da6x5rxa	20	18	single	single	JJ
cord-258708-da6x5rxa	20	19	positivestranded	positivestranded	JJ
cord-258708-da6x5rxa	20	20	ribonucleic	ribonucleic	NN
cord-258708-da6x5rxa	20	21	acid	acid	NN
cord-258708-da6x5rxa	20	22	(	(	-LRB-
cord-258708-da6x5rxa	20	23	RNA	RNA	NNP
cord-258708-da6x5rxa	20	24	)	)	-RRB-
cord-258708-da6x5rxa	20	25	,	,	,
cord-258708-da6x5rxa	20	26	typically	typically	RB
cord-258708-da6x5rxa	20	27	ranging	range	VBG
cord-258708-da6x5rxa	20	28	from	from	IN
cord-258708-da6x5rxa	20	29	26	26	CD
cord-258708-da6x5rxa	20	30	to	to	IN
cord-258708-da6x5rxa	20	31	32kbs	32kbs	NN
cord-258708-da6x5rxa	20	32	in	in	IN
cord-258708-da6x5rxa	20	33	length	length	NN
cord-258708-da6x5rxa	20	34	.	.	.
cord-258708-da6x5rxa	21	1	The	the	DT
cord-258708-da6x5rxa	21	2	SARS	SARS	NNP
cord-258708-da6x5rxa	21	3	-	-	HYPH
cord-258708-da6x5rxa	21	4	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	21	5	is	be	VBZ
cord-258708-da6x5rxa	21	6	a	a	DT
cord-258708-da6x5rxa	21	7	novel	novel	NN
cord-258708-da6x5rxa	21	8	β	β	NN
cord-258708-da6x5rxa	21	9	-	-	HYPH
cord-258708-da6x5rxa	21	10	coronavirus	coronavirus	NN
cord-258708-da6x5rxa	21	11	category	category	NN
cord-258708-da6x5rxa	21	12	that	that	WDT
cord-258708-da6x5rxa	21	13	takes	take	VBZ
cord-258708-da6x5rxa	21	14	a	a	DT
cord-258708-da6x5rxa	21	15	round	round	JJ
cord-258708-da6x5rxa	21	16	or	or	CC
cord-258708-da6x5rxa	21	17	elliptic	elliptic	JJ
cord-258708-da6x5rxa	21	18	pleomorphic	pleomorphic	JJ
cord-258708-da6x5rxa	21	19	form	form	NN
cord-258708-da6x5rxa	21	20	(	(	-LRB-
cord-258708-da6x5rxa	21	21	Figure	figure	NN
cord-258708-da6x5rxa	21	22	1	1	CD
cord-258708-da6x5rxa	21	23	)	)	-RRB-
cord-258708-da6x5rxa	21	24	.	.	.
cord-258708-da6x5rxa	22	1	Metagenomics	metagenomic	NNS
cord-258708-da6x5rxa	22	2	analysis	analysis	NN
cord-258708-da6x5rxa	22	3	from	from	IN
cord-258708-da6x5rxa	22	4	next	next	JJ
cord-258708-da6x5rxa	22	5	-	-	HYPH
cord-258708-da6x5rxa	22	6	generation	generation	NN
cord-258708-da6x5rxa	22	7	sequencing	sequencing	NN
cord-258708-da6x5rxa	22	8	convincingly	convincingly	RB
cord-258708-da6x5rxa	22	9	demonstrate	demonstrate	VBP
cord-258708-da6x5rxa	22	10	this	this	DT
cord-258708-da6x5rxa	22	11	virus	virus	NN
cord-258708-da6x5rxa	22	12	consists	consist	VBZ
cord-258708-da6x5rxa	22	13	of	of	IN
cord-258708-da6x5rxa	22	14	six	six	CD
cord-258708-da6x5rxa	22	15	major	major	JJ
cord-258708-da6x5rxa	22	16	open	open	JJ
cord-258708-da6x5rxa	22	17	-	-	HYPH
cord-258708-da6x5rxa	22	18	reading	read	VBG
cord-258708-da6x5rxa	22	19	frames	frame	NNS
cord-258708-da6x5rxa	22	20	(	(	-LRB-
cord-258708-da6x5rxa	22	21	ORFs	ORFs	NNP
cord-258708-da6x5rxa	22	22	)	)	-RRB-
cord-258708-da6x5rxa	22	23	that	that	WDT
cord-258708-da6x5rxa	22	24	are	be	VBP
cord-258708-da6x5rxa	22	25	common	common	JJ
cord-258708-da6x5rxa	22	26	to	to	IN
cord-258708-da6x5rxa	22	27	coronaviruses	coronaviruse	NNS
cord-258708-da6x5rxa	22	28	,	,	,
cord-258708-da6x5rxa	22	29	and	and	CC
cord-258708-da6x5rxa	22	30	a	a	DT
cord-258708-da6x5rxa	22	31	number	number	NN
cord-258708-da6x5rxa	22	32	of	of	IN
cord-258708-da6x5rxa	22	33	other	other	JJ
cord-258708-da6x5rxa	22	34	accessory	accessory	JJ
cord-258708-da6x5rxa	22	35	genes	gene	NNS
cord-258708-da6x5rxa	22	36	(	(	-LRB-
cord-258708-da6x5rxa	22	37	5	5	CD
cord-258708-da6x5rxa	22	38	)	)	-RRB-
cord-258708-da6x5rxa	22	39	.	.	.
cord-258708-da6x5rxa	23	1	Further	further	JJ
cord-258708-da6x5rxa	23	2	analysis	analysis	NN
cord-258708-da6x5rxa	23	3	indicates	indicate	VBZ
cord-258708-da6x5rxa	23	4	some	some	DT
cord-258708-da6x5rxa	23	5	of	of	IN
cord-258708-da6x5rxa	23	6	the	the	DT
cord-258708-da6x5rxa	23	7	expressed	express	VBN
cord-258708-da6x5rxa	23	8	genes	gene	NNS
cord-258708-da6x5rxa	23	9	share	share	VBP
cord-258708-da6x5rxa	23	10	less	less	JJR
cord-258708-da6x5rxa	23	11	than	than	IN
cord-258708-da6x5rxa	23	12	80	80	CD
cord-258708-da6x5rxa	23	13	%	%	NN
cord-258708-da6x5rxa	23	14	nucleotide	nucleotide	JJ
cord-258708-da6x5rxa	23	15	sequence	sequence	NN
cord-258708-da6x5rxa	23	16	identity	identity	NN
cord-258708-da6x5rxa	23	17	to	to	IN
cord-258708-da6x5rxa	23	18	earlier	early	JJR
cord-258708-da6x5rxa	23	19	SARS	SARS	NNP
cord-258708-da6x5rxa	23	20	-	-	HYPH
cord-258708-da6x5rxa	23	21	CoV	CoV	NNP
cord-258708-da6x5rxa	23	22	(	(	-LRB-
cord-258708-da6x5rxa	23	23	6	6	CD
cord-258708-da6x5rxa	23	24	)	)	-RRB-
cord-258708-da6x5rxa	23	25	.	.	.
cord-258708-da6x5rxa	24	1	The	the	DT
cord-258708-da6x5rxa	24	2	SARS	SARS	NNP
cord-258708-da6x5rxa	24	3	-	-	HYPH
cord-258708-da6x5rxa	24	4	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	24	5	RNA	RNA	NNP
cord-258708-da6x5rxa	24	6	genome	genome	NN
cord-258708-da6x5rxa	24	7	contains	contain	VBZ
cord-258708-da6x5rxa	24	8	29891	29891	CD
cord-258708-da6x5rxa	24	9	nucleotides	nucleotide	NNS
cord-258708-da6x5rxa	24	10	,	,	,
cord-258708-da6x5rxa	24	11	encoding	encode	VBG
cord-258708-da6x5rxa	24	12	for	for	IN
cord-258708-da6x5rxa	24	13	9860	9860	CD
cord-258708-da6x5rxa	24	14	amino	amino	JJ
cord-258708-da6x5rxa	24	15	acids	acid	NNS
cord-258708-da6x5rxa	24	16	(	(	-LRB-
cord-258708-da6x5rxa	24	17	6	6	CD
cord-258708-da6x5rxa	24	18	)	)	-RRB-
cord-258708-da6x5rxa	24	19	.	.	.
cord-258708-da6x5rxa	25	1	Although	although	IN
cord-258708-da6x5rxa	25	2	its	-PRON-	PRP$
cord-258708-da6x5rxa	25	3	probable	probable	JJ
cord-258708-da6x5rxa	25	4	origins	origin	NNS
cord-258708-da6x5rxa	25	5	are	be	VBP
cord-258708-da6x5rxa	25	6	not	not	RB
cord-258708-da6x5rxa	25	7	completely	completely	RB
cord-258708-da6x5rxa	25	8	understood	understand	VBN
cord-258708-da6x5rxa	25	9	,	,	,
cord-258708-da6x5rxa	25	10	genomic	genomic	JJ
cord-258708-da6x5rxa	25	11	analyses	analysis	NNS
cord-258708-da6x5rxa	25	12	suggest	suggest	VBP
cord-258708-da6x5rxa	25	13	that	that	IN
cord-258708-da6x5rxa	25	14	it	-PRON-	PRP
cord-258708-da6x5rxa	25	15	probably	probably	RB
cord-258708-da6x5rxa	25	16	evolved	evolve	VBD
cord-258708-da6x5rxa	25	17	from	from	IN
cord-258708-da6x5rxa	25	18	a	a	DT
cord-258708-da6x5rxa	25	19	strain	strain	NN
cord-258708-da6x5rxa	25	20	found	find	VBN
cord-258708-da6x5rxa	25	21	in	in	IN
cord-258708-da6x5rxa	25	22	bats	bat	NNS
cord-258708-da6x5rxa	25	23	(	(	-LRB-
cord-258708-da6x5rxa	25	24	7	7	CD
cord-258708-da6x5rxa	25	25	,	,	,
cord-258708-da6x5rxa	25	26	8)	8)	NN
cord-258708-da6x5rxa	25	27	.	.	.
cord-258708-da6x5rxa	26	1	Similar	similar	JJ
cord-258708-da6x5rxa	26	2	to	to	IN
cord-258708-da6x5rxa	26	3	most	most	JJS
cord-258708-da6x5rxa	26	4	other	other	JJ
cord-258708-da6x5rxa	26	5	coronaviruses	coronaviruse	NNS
cord-258708-da6x5rxa	26	6	,	,	,
cord-258708-da6x5rxa	26	7	the	the	DT
cord-258708-da6x5rxa	26	8	outer	outer	JJ
cord-258708-da6x5rxa	26	9	membrane	membrane	NN
cord-258708-da6x5rxa	26	10	spike	spike	NN
cord-258708-da6x5rxa	26	11	glycoprotein	glycoprotein	NN
cord-258708-da6x5rxa	26	12	of	of	IN
cord-258708-da6x5rxa	26	13	SARS	SARS	NNP
cord-258708-da6x5rxa	26	14	-	-	HYPH
cord-258708-da6x5rxa	26	15	Cov-2	Cov-2	NNP
cord-258708-da6x5rxa	26	16	,	,	,
cord-258708-da6x5rxa	26	17	is	be	VBZ
cord-258708-da6x5rxa	26	18	the	the	DT
cord-258708-da6x5rxa	26	19	prime	prime	NN
cord-258708-da6x5rxa	26	20	interacting	interact	VBG
cord-258708-da6x5rxa	26	21	protein	protein	NN
cord-258708-da6x5rxa	26	22	with	with	IN
cord-258708-da6x5rxa	26	23	host	host	NN
cord-258708-da6x5rxa	26	24	cell	cell	NN
cord-258708-da6x5rxa	26	25	target	target	NN
cord-258708-da6x5rxa	26	26	receptors	receptor	NNS
cord-258708-da6x5rxa	26	27	(	(	-LRB-
cord-258708-da6x5rxa	26	28	such	such	JJ
cord-258708-da6x5rxa	26	29	as	as	IN
cord-258708-da6x5rxa	26	30	ACE2	ACE2	NNP
cord-258708-da6x5rxa	26	31	,	,	,
cord-258708-da6x5rxa	26	32	CD26	CD26	NNP
cord-258708-da6x5rxa	26	33	,	,	,
cord-258708-da6x5rxa	26	34	Ezrin	Ezrin	NNP
cord-258708-da6x5rxa	26	35	,	,	,
cord-258708-da6x5rxa	26	36	cyclophilins	cyclophilins	NNP
cord-258708-da6x5rxa	26	37	)	)	-RRB-
cord-258708-da6x5rxa	26	38	which	which	WDT
cord-258708-da6x5rxa	26	39	are	be	VBP
cord-258708-da6x5rxa	26	40	important	important	JJ
cord-258708-da6x5rxa	26	41	for	for	IN
cord-258708-da6x5rxa	26	42	cell	cell	NN
cord-258708-da6x5rxa	26	43	adhesion	adhesion	NN
cord-258708-da6x5rxa	26	44	,	,	,
cord-258708-da6x5rxa	26	45	and	and	CC
cord-258708-da6x5rxa	26	46	virulence	virulence	NN
cord-258708-da6x5rxa	26	47	(	(	-LRB-
cord-258708-da6x5rxa	26	48	9	9	CD
cord-258708-da6x5rxa	26	49	)	)	-RRB-
cord-258708-da6x5rxa	26	50	.	.	.
cord-258708-da6x5rxa	27	1	Under	under	IN
cord-258708-da6x5rxa	27	2	an	an	DT
cord-258708-da6x5rxa	27	3	electron	electron	NN
cord-258708-da6x5rxa	27	4	microscope	microscope	NN
cord-258708-da6x5rxa	27	5	,	,	,
cord-258708-da6x5rxa	27	6	the	the	DT
cord-258708-da6x5rxa	27	7	SARS	SARS	NNP
cord-258708-da6x5rxa	27	8	-	-	HYPH
cord-258708-da6x5rxa	27	9	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	27	10	surface	surface	NN
cord-258708-da6x5rxa	27	11	morphology	morphology	NN
cord-258708-da6x5rxa	27	12	possesses	possess	VBZ
cord-258708-da6x5rxa	27	13	multiple	multiple	JJ
cord-258708-da6x5rxa	27	14	polyproteins	polyprotein	NNS
cord-258708-da6x5rxa	27	15	,	,	,
cord-258708-da6x5rxa	27	16	nucleoproteins	nucleoprotein	NNS
cord-258708-da6x5rxa	27	17	,	,	,
cord-258708-da6x5rxa	27	18	and	and	CC
cord-258708-da6x5rxa	27	19	membrane	membrane	NN
cord-258708-da6x5rxa	27	20	proteins	protein	NNS
cord-258708-da6x5rxa	27	21	,	,	,
cord-258708-da6x5rxa	27	22	such	such	JJ
cord-258708-da6x5rxa	27	23	as	as	IN
cord-258708-da6x5rxa	27	24	spike	spike	NN
cord-258708-da6x5rxa	27	25	glycoproteins	glycoprotein	NNS
cord-258708-da6x5rxa	27	26	S	s	NN
cord-258708-da6x5rxa	27	27	(	(	-LRB-
cord-258708-da6x5rxa	27	28	10	10	CD
cord-258708-da6x5rxa	27	29	)	)	-RRB-
cord-258708-da6x5rxa	27	30	.	.	.
cord-258708-da6x5rxa	28	1	The	the	DT
cord-258708-da6x5rxa	28	2	latter	latter	JJ
cord-258708-da6x5rxa	28	3	involves	involve	VBZ
cord-258708-da6x5rxa	28	4	homotrimers	homotrimer	NNS
cord-258708-da6x5rxa	28	5	protruding	protrude	VBG
cord-258708-da6x5rxa	28	6	far	far	RB
cord-258708-da6x5rxa	28	7	from	from	IN
cord-258708-da6x5rxa	28	8	the	the	DT
cord-258708-da6x5rxa	28	9	viral	viral	JJ
cord-258708-da6x5rxa	28	10	surface	surface	NN
cord-258708-da6x5rxa	28	11	,	,	,
cord-258708-da6x5rxa	28	12	giving	give	VBG
cord-258708-da6x5rxa	28	13	it	-PRON-	PRP
cord-258708-da6x5rxa	28	14	a	a	DT
cord-258708-da6x5rxa	28	15	halo	halo	NN
cord-258708-da6x5rxa	28	16	like	like	IN
cord-258708-da6x5rxa	28	17	appearance	appearance	NN
cord-258708-da6x5rxa	28	18	or	or	CC
cord-258708-da6x5rxa	28	19	corona	corona	NN
cord-258708-da6x5rxa	28	20	as	as	IN
cord-258708-da6x5rxa	28	21	illustrated	illustrate	VBN
cord-258708-da6x5rxa	28	22	in	in	IN
cord-258708-da6x5rxa	28	23	Figure	Figure	NNP
cord-258708-da6x5rxa	28	24	1	1	CD
cord-258708-da6x5rxa	28	25	.	.	.
cord-258708-da6x5rxa	29	1	COVID-19	covid-19	JJ
cord-258708-da6x5rxa	29	2	patients	patient	NNS
cord-258708-da6x5rxa	29	3	presented	present	VBN
cord-258708-da6x5rxa	29	4	with	with	IN
cord-258708-da6x5rxa	29	5	mild	mild	JJ
cord-258708-da6x5rxa	29	6	flu	flu	NN
cord-258708-da6x5rxa	29	7	-	-	HYPH
cord-258708-da6x5rxa	29	8	like	like	JJ
cord-258708-da6x5rxa	29	9	symptoms	symptom	NNS
cord-258708-da6x5rxa	29	10	,	,	,
cord-258708-da6x5rxa	29	11	and	and	CC
cord-258708-da6x5rxa	29	12	a	a	DT
cord-258708-da6x5rxa	29	13	few	few	JJ
cord-258708-da6x5rxa	29	14	patients	patient	NNS
cord-258708-da6x5rxa	29	15	rapidly	rapidly	RB
cord-258708-da6x5rxa	29	16	develop	develop	VBP
cord-258708-da6x5rxa	29	17	acute	acute	JJ
cord-258708-da6x5rxa	29	18	respiratory	respiratory	JJ
cord-258708-da6x5rxa	29	19	distress	distress	NN
cord-258708-da6x5rxa	29	20	syndrome	syndrome	NN
cord-258708-da6x5rxa	29	21	,	,	,
cord-258708-da6x5rxa	29	22	respiratory	respiratory	JJ
cord-258708-da6x5rxa	29	23	failure	failure	NN
cord-258708-da6x5rxa	29	24	,	,	,
cord-258708-da6x5rxa	29	25	multiple	multiple	JJ
cord-258708-da6x5rxa	29	26	organ	organ	NN
cord-258708-da6x5rxa	29	27	failure	failure	NN
cord-258708-da6x5rxa	29	28	,	,	,
cord-258708-da6x5rxa	29	29	and	and	CC
cord-258708-da6x5rxa	29	30	even	even	RB
cord-258708-da6x5rxa	29	31	deaths	death	NNS
cord-258708-da6x5rxa	29	32	(	(	-LRB-
cord-258708-da6x5rxa	29	33	Table	table	NN
cord-258708-da6x5rxa	29	34	1	1	CD
cord-258708-da6x5rxa	29	35	)	)	-RRB-
cord-258708-da6x5rxa	29	36	.	.	.
cord-258708-da6x5rxa	30	1	In	in	IN
cord-258708-da6x5rxa	30	2	the	the	DT
cord-258708-da6x5rxa	30	3	initial	initial	JJ
cord-258708-da6x5rxa	30	4	step	step	NN
cord-258708-da6x5rxa	30	5	of	of	IN
cord-258708-da6x5rxa	30	6	the	the	DT
cord-258708-da6x5rxa	30	7	infection	infection	NN
cord-258708-da6x5rxa	30	8	,	,	,
cord-258708-da6x5rxa	30	9	studies	study	NNS
cord-258708-da6x5rxa	30	10	support	support	VBP
cord-258708-da6x5rxa	30	11	a	a	DT
cord-258708-da6x5rxa	30	12	potential	potential	JJ
cord-258708-da6x5rxa	30	13	interaction	interaction	NN
cord-258708-da6x5rxa	30	14	between	between	IN
cord-258708-da6x5rxa	30	15	SARS	SARS	NNP
cord-258708-da6x5rxa	30	16	-	-	HYPH
cord-258708-da6x5rxa	30	17	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	30	18	,	,	,
cord-258708-da6x5rxa	30	19	and	and	CC
cord-258708-da6x5rxa	30	20	ACE2	ACE2	NNP
cord-258708-da6x5rxa	30	21	receptor	receptor	NN
cord-258708-da6x5rxa	30	22	as	as	IN
cord-258708-da6x5rxa	30	23	a	a	DT
cord-258708-da6x5rxa	30	24	portal	portal	NN
cord-258708-da6x5rxa	30	25	of	of	IN
cord-258708-da6x5rxa	30	26	infection	infection	NN
cord-258708-da6x5rxa	30	27	(	(	-LRB-
cord-258708-da6x5rxa	30	28	Figure	figure	NN
cord-258708-da6x5rxa	30	29	2	2	CD
cord-258708-da6x5rxa	30	30	)	)	-RRB-
cord-258708-da6x5rxa	30	31	(	(	-LRB-
cord-258708-da6x5rxa	30	32	9	9	CD
cord-258708-da6x5rxa	30	33	,	,	,
cord-258708-da6x5rxa	30	34	11	11	CD
cord-258708-da6x5rxa	30	35	)	)	-RRB-
cord-258708-da6x5rxa	30	36	.	.	.
cord-258708-da6x5rxa	31	1	ACE2	ACE2	NNP
cord-258708-da6x5rxa	31	2	is	be	VBZ
cord-258708-da6x5rxa	31	3	a	a	DT
cord-258708-da6x5rxa	31	4	type	type	NN
cord-258708-da6x5rxa	31	5	1	1	CD
cord-258708-da6x5rxa	31	6	transmembrane	transmembrane	NN
cord-258708-da6x5rxa	31	7	protein	protein	NN
cord-258708-da6x5rxa	31	8	predominantly	predominantly	RB
cord-258708-da6x5rxa	31	9	expressed	express	VBN
cord-258708-da6x5rxa	31	10	by	by	IN
cord-258708-da6x5rxa	31	11	epithelial	epithelial	JJ
cord-258708-da6x5rxa	31	12	cells	cell	NNS
cord-258708-da6x5rxa	31	13	of	of	IN
cord-258708-da6x5rxa	31	14	the	the	DT
cord-258708-da6x5rxa	31	15	lung	lung	NN
cord-258708-da6x5rxa	31	16	(	(	-LRB-
cord-258708-da6x5rxa	31	17	12	12	CD
cord-258708-da6x5rxa	31	18	)	)	-RRB-
cord-258708-da6x5rxa	31	19	.	.	.
cord-258708-da6x5rxa	32	1	When	when	WRB
cord-258708-da6x5rxa	32	2	compared	compare	VBN
cord-258708-da6x5rxa	32	3	to	to	IN
cord-258708-da6x5rxa	32	4	other	other	JJ
cord-258708-da6x5rxa	32	5	viruses	virus	NNS
cord-258708-da6x5rxa	32	6	that	that	WDT
cord-258708-da6x5rxa	32	7	cause	cause	VBP
cord-258708-da6x5rxa	32	8	SARS	SARS	NNP
cord-258708-da6x5rxa	32	9	,	,	,
cord-258708-da6x5rxa	32	10	there	there	EX
cord-258708-da6x5rxa	32	11	are	be	VBP
cord-258708-da6x5rxa	32	12	some	some	DT
cord-258708-da6x5rxa	32	13	differences	difference	NNS
cord-258708-da6x5rxa	32	14	in	in	IN
cord-258708-da6x5rxa	32	15	the	the	DT
cord-258708-da6x5rxa	32	16	precise	precise	JJ
cord-258708-da6x5rxa	32	17	amino	amino	NN
cord-258708-da6x5rxa	32	18	acids	acid	NNS
cord-258708-da6x5rxa	32	19	belong	belong	VBP
cord-258708-da6x5rxa	32	20	to	to	IN
cord-258708-da6x5rxa	32	21	spike	spike	NN
cord-258708-da6x5rxa	32	22	glycoprotein	glycoprotein	NN
cord-258708-da6x5rxa	32	23	used	use	VBN
cord-258708-da6x5rxa	32	24	to	to	TO
cord-258708-da6x5rxa	32	25	bind	bind	VB
cord-258708-da6x5rxa	32	26	SARS	SARS	NNP
cord-258708-da6x5rxa	32	27	-	-	HYPH
cord-258708-da6x5rxa	32	28	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	32	29	to	to	IN
cord-258708-da6x5rxa	32	30	that	that	DT
cord-258708-da6x5rxa	32	31	ACE2	ACE2	NNP
cord-258708-da6x5rxa	32	32	receptor	receptor	NN
cord-258708-da6x5rxa	32	33	.	.	.
cord-258708-da6x5rxa	33	1	Distinctly	distinctly	RB
cord-258708-da6x5rxa	33	2	,	,	,
cord-258708-da6x5rxa	33	3	a	a	DT
cord-258708-da6x5rxa	33	4	larger	large	JJR
cord-258708-da6x5rxa	33	5	sequence	sequence	NN
cord-258708-da6x5rxa	33	6	difference	difference	NN
cord-258708-da6x5rxa	33	7	(	(	-LRB-
cord-258708-da6x5rxa	33	8	∼55	∼55	NN
cord-258708-da6x5rxa	33	9	%	%	NN
cord-258708-da6x5rxa	33	10	identity	identity	NN
cord-258708-da6x5rxa	33	11	)	)	-RRB-
cord-258708-da6x5rxa	33	12	between	between	IN
cord-258708-da6x5rxa	33	13	SARS	SARS	NNP
cord-258708-da6x5rxa	33	14	-	-	HYPH
cord-258708-da6x5rxa	33	15	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	33	16	,	,	,
cord-258708-da6x5rxa	33	17	and	and	CC
cord-258708-da6x5rxa	33	18	SARS	SARS	NNP
cord-258708-da6x5rxa	33	19	-	-	HYPH
cord-258708-da6x5rxa	33	20	CoV	CoV	NNP
cord-258708-da6x5rxa	33	21	was	be	VBD
cord-258708-da6x5rxa	33	22	found	find	VBN
cord-258708-da6x5rxa	33	23	in	in	IN
cord-258708-da6x5rxa	33	24	the	the	DT
cord-258708-da6x5rxa	33	25	S1	S1	NNP
cord-258708-da6x5rxa	33	26	domain	domain	NN
cord-258708-da6x5rxa	33	27	of	of	IN
cord-258708-da6x5rxa	33	28	the	the	DT
cord-258708-da6x5rxa	33	29	spike	spike	NN
cord-258708-da6x5rxa	33	30	glycoprotein	glycoprotein	NN
cord-258708-da6x5rxa	33	31	S	s	NN
cord-258708-da6x5rxa	33	32	(	(	-LRB-
cord-258708-da6x5rxa	33	33	aa01-aa550	aa01-aa550	RB
cord-258708-da6x5rxa	33	34	)	)	-RRB-
cord-258708-da6x5rxa	33	35	(	(	-LRB-
cord-258708-da6x5rxa	33	36	9	9	CD
cord-258708-da6x5rxa	33	37	)	)	-RRB-
cord-258708-da6x5rxa	33	38	.	.	.
cord-258708-da6x5rxa	34	1	This	this	DT
cord-258708-da6x5rxa	34	2	domain	domain	NN
cord-258708-da6x5rxa	34	3	is	be	VBZ
cord-258708-da6x5rxa	34	4	recognized	recognize	VBN
cord-258708-da6x5rxa	34	5	for	for	IN
cord-258708-da6x5rxa	34	6	host	host	NN
cord-258708-da6x5rxa	34	7	cell	cell	NN
cord-258708-da6x5rxa	34	8	target	target	NN
cord-258708-da6x5rxa	34	9	contact	contact	NN
cord-258708-da6x5rxa	34	10	(	(	-LRB-
cord-258708-da6x5rxa	34	11	9	9	CD
cord-258708-da6x5rxa	34	12	)	)	-RRB-
cord-258708-da6x5rxa	34	13	.	.	.
cord-258708-da6x5rxa	35	1	The	the	DT
cord-258708-da6x5rxa	35	2	receptor	receptor	NN
cord-258708-da6x5rxa	35	3	-	-	HYPH
cord-258708-da6x5rxa	35	4	binding	bind	VBG
cord-258708-da6x5rxa	35	5	domain	domain	NN
cord-258708-da6x5rxa	35	6	(	(	-LRB-
cord-258708-da6x5rxa	35	7	RBD	RBD	NNP
cord-258708-da6x5rxa	35	8	)	)	-RRB-
cord-258708-da6x5rxa	35	9	of	of	IN
cord-258708-da6x5rxa	35	10	SARS	SARS	NNP
cord-258708-da6x5rxa	35	11	-	-	HYPH
cord-258708-da6x5rxa	35	12	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	35	13	,	,	,
cord-258708-da6x5rxa	35	14	and	and	CC
cord-258708-da6x5rxa	35	15	SARS	SARS	NNP
cord-258708-da6x5rxa	35	16	-	-	HYPH
cord-258708-da6x5rxa	35	17	CoV	CoV	NNP
cord-258708-da6x5rxa	35	18	interacts	interact	VBZ
cord-258708-da6x5rxa	35	19	with	with	IN
cord-258708-da6x5rxa	35	20	ACE2	ACE2	NNP
cord-258708-da6x5rxa	35	21	receptor	receptor	NN
cord-258708-da6x5rxa	35	22	(	(	-LRB-
cord-258708-da6x5rxa	35	23	9	9	CD
cord-258708-da6x5rxa	35	24	)	)	-RRB-
cord-258708-da6x5rxa	35	25	.	.	.
cord-258708-da6x5rxa	36	1	Interface	interface	NN
cord-258708-da6x5rxa	36	2	comparison	comparison	NN
cord-258708-da6x5rxa	36	3	between	between	IN
cord-258708-da6x5rxa	36	4	the	the	DT
cord-258708-da6x5rxa	36	5	RBD	RBD	NNP
cord-258708-da6x5rxa	36	6	in	in	IN
cord-258708-da6x5rxa	36	7	SARS	SARS	NNP
cord-258708-da6x5rxa	36	8	-	-	HYPH
cord-258708-da6x5rxa	36	9	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	36	10	,	,	,
cord-258708-da6x5rxa	36	11	and	and	CC
cord-258708-da6x5rxa	36	12	SARS	SARS	NNP
cord-258708-da6x5rxa	36	13	-	-	HYPH
cord-258708-da6x5rxa	36	14	CoV	CoV	NNP
cord-258708-da6x5rxa	36	15	indicates	indicate	VBZ
cord-258708-da6x5rxa	36	16	that	that	IN
cord-258708-da6x5rxa	36	17	the	the	DT
cord-258708-da6x5rxa	36	18	most	most	RBS
cord-258708-da6x5rxa	36	19	prominent	prominent	JJ
cord-258708-da6x5rxa	36	20	alteration	alteration	NN
cord-258708-da6x5rxa	36	21	is	be	VBZ
cord-258708-da6x5rxa	36	22	the	the	DT
cord-258708-da6x5rxa	36	23	substitution	substitution	NN
cord-258708-da6x5rxa	36	24	of	of	IN
cord-258708-da6x5rxa	36	25	Val404	val404	NN
cord-258708-da6x5rxa	36	26	in	in	IN
cord-258708-da6x5rxa	36	27	the	the	DT
cord-258708-da6x5rxa	36	28	SARS	SARS	NNP
cord-258708-da6x5rxa	36	29	-	-	HYPH
cord-258708-da6x5rxa	36	30	CoV	CoV	NNP
cord-258708-da6x5rxa	36	31	-	-	HYPH
cord-258708-da6x5rxa	36	32	RBD	RBD	NNP
cord-258708-da6x5rxa	36	33	with	with	IN
cord-258708-da6x5rxa	36	34	Lys417	Lys417	NFP
cord-258708-da6x5rxa	36	35	in	in	IN
cord-258708-da6x5rxa	36	36	the	the	DT
cord-258708-da6x5rxa	36	37	SARS	SARS	NNP
cord-258708-da6x5rxa	36	38	-	-	HYPH
cord-258708-da6x5rxa	36	39	CoV-2-RBD	CoV-2-RBD	NNP
cord-258708-da6x5rxa	36	40	(	(	-LRB-
cord-258708-da6x5rxa	36	41	11	11	CD
cord-258708-da6x5rxa	36	42	)	)	-RRB-
cord-258708-da6x5rxa	36	43	.	.	.
cord-258708-da6x5rxa	37	1	The	the	DT
cord-258708-da6x5rxa	37	2	high	high	JJ
cord-258708-da6x5rxa	37	3	infectivity	infectivity	NN
cord-258708-da6x5rxa	37	4	of	of	IN
cord-258708-da6x5rxa	37	5	the	the	DT
cord-258708-da6x5rxa	37	6	SARS	SARS	NNP
cord-258708-da6x5rxa	37	7	-	-	HYPH
cord-258708-da6x5rxa	37	8	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	37	9	virus	virus	NN
cord-258708-da6x5rxa	37	10	is	be	VBZ
cord-258708-da6x5rxa	37	11	in	in	IN
cord-258708-da6x5rxa	37	12	part	part	NN
cord-258708-da6x5rxa	37	13	related	relate	VBN
cord-258708-da6x5rxa	37	14	to	to	IN
cord-258708-da6x5rxa	37	15	new	new	JJ
cord-258708-da6x5rxa	37	16	mutations	mutation	NNS
cord-258708-da6x5rxa	37	17	in	in	IN
cord-258708-da6x5rxa	37	18	the	the	DT
cord-258708-da6x5rxa	37	19	RBD	RBD	NNP
cord-258708-da6x5rxa	37	20	,	,	,
cord-258708-da6x5rxa	37	21	and	and	CC
cord-258708-da6x5rxa	37	22	acquisition	acquisition	NN
cord-258708-da6x5rxa	37	23	of	of	IN
cord-258708-da6x5rxa	37	24	a	a	DT
cord-258708-da6x5rxa	37	25	furin	furin	NN
cord-258708-da6x5rxa	37	26	cleavage	cleavage	NN
cord-258708-da6x5rxa	37	27	site	site	NN
cord-258708-da6x5rxa	37	28	.	.	.
cord-258708-da6x5rxa	38	1	The	the	DT
cord-258708-da6x5rxa	38	2	latter	latter	JJ
cord-258708-da6x5rxa	38	3	mutation	mutation	NN
cord-258708-da6x5rxa	38	4	is	be	VBZ
cord-258708-da6x5rxa	38	5	inserted	insert	VBN
cord-258708-da6x5rxa	38	6	at	at	IN
cord-258708-da6x5rxa	38	7	the	the	DT
cord-258708-da6x5rxa	38	8	boundary	boundary	NN
cord-258708-da6x5rxa	38	9	of	of	IN
cord-258708-da6x5rxa	38	10	the	the	DT
cord-258708-da6x5rxa	38	11	S1	S1	NNP
cord-258708-da6x5rxa	38	12	/	/	SYM
cord-258708-da6x5rxa	38	13	S2	S2	NNP
cord-258708-da6x5rxa	38	14	subunits	subunit	NNS
cord-258708-da6x5rxa	38	15	of	of	IN
cord-258708-da6x5rxa	38	16	the	the	DT
cord-258708-da6x5rxa	38	17	spike	spike	NN
cord-258708-da6x5rxa	38	18	S	s	NN
cord-258708-da6x5rxa	38	19	-	-	HYPH
cord-258708-da6x5rxa	38	20	protein	protein	NN
cord-258708-da6x5rxa	38	21	(	(	-LRB-
cord-258708-da6x5rxa	38	22	13	13	CD
cord-258708-da6x5rxa	38	23	)	)	-RRB-
cord-258708-da6x5rxa	38	24	.	.	.
cord-258708-da6x5rxa	39	1	Moreover	moreover	RB
cord-258708-da6x5rxa	39	2	,	,	,
cord-258708-da6x5rxa	39	3	the	the	DT
cord-258708-da6x5rxa	39	4	furin	furin	NN
cord-258708-da6x5rxa	39	5	binding	bind	VBG
cord-258708-da6x5rxa	39	6	site	site	NN
cord-258708-da6x5rxa	39	7	can	can	MD
cord-258708-da6x5rxa	39	8	enhance	enhance	VB
cord-258708-da6x5rxa	39	9	the	the	DT
cord-258708-da6x5rxa	39	10	virus	virus	NN
cord-258708-da6x5rxa	39	11	ability	ability	NN
cord-258708-da6x5rxa	39	12	to	to	TO
cord-258708-da6x5rxa	39	13	internalize	internalize	VB
cord-258708-da6x5rxa	39	14	into	into	IN
cord-258708-da6x5rxa	39	15	cells	cell	NNS
cord-258708-da6x5rxa	39	16	(	(	-LRB-
cord-258708-da6x5rxa	39	17	12	12	CD
cord-258708-da6x5rxa	39	18	)	)	-RRB-
cord-258708-da6x5rxa	39	19	.	.	.
cord-258708-da6x5rxa	40	1	Initially	initially	RB
cord-258708-da6x5rxa	40	2	,	,	,
cord-258708-da6x5rxa	40	3	membrane	membrane	NN
cord-258708-da6x5rxa	40	4	bound	bind	VBN
cord-258708-da6x5rxa	40	5	ACE2	ACE2	NNP
cord-258708-da6x5rxa	40	6	proteins	protein	NNS
cord-258708-da6x5rxa	40	7	are	be	VBP
cord-258708-da6x5rxa	40	8	cleaved	cleave	VBN
cord-258708-da6x5rxa	40	9	by	by	IN
cord-258708-da6x5rxa	40	10	A	a	DT
cord-258708-da6x5rxa	40	11	Disintegrin	Disintegrin	NNP
cord-258708-da6x5rxa	40	12	And	and	CC
cord-258708-da6x5rxa	40	13	Metalloproteases	Metalloproteases	NNP
cord-258708-da6x5rxa	40	14	17	17	CD
cord-258708-da6x5rxa	40	15	(	(	-LRB-
cord-258708-da6x5rxa	40	16	ADAM17	adam17	NN
cord-258708-da6x5rxa	40	17	)	)	-RRB-
cord-258708-da6x5rxa	40	18	that	that	WDT
cord-258708-da6x5rxa	40	19	is	be	VBZ
cord-258708-da6x5rxa	40	20	upregulated	upregulate	VBN
cord-258708-da6x5rxa	40	21	by	by	IN
cord-258708-da6x5rxa	40	22	endocytosed	endocytose	VBN
cord-258708-da6x5rxa	40	23	SARS	SARS	NNP
cord-258708-da6x5rxa	40	24	-	-	HYPH
cord-258708-da6x5rxa	40	25	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	40	26	spike	spike	NN
cord-258708-da6x5rxa	40	27	S	s	NN
cord-258708-da6x5rxa	40	28	proteins	protein	NNS
cord-258708-da6x5rxa	40	29	(	(	-LRB-
cord-258708-da6x5rxa	40	30	Figure	figure	NN
cord-258708-da6x5rxa	40	31	2	2	CD
cord-258708-da6x5rxa	40	32	)	)	-RRB-
cord-258708-da6x5rxa	40	33	.	.	.
cord-258708-da6x5rxa	41	1	Moreover	moreover	RB
cord-258708-da6x5rxa	41	2	,	,	,
cord-258708-da6x5rxa	41	3	ACE2	ACE2	NNP
cord-258708-da6x5rxa	41	4	contains	contain	VBZ
cord-258708-da6x5rxa	41	5	an	an	DT
cord-258708-da6x5rxa	41	6	enzymatic	enzymatic	JJ
cord-258708-da6x5rxa	41	7	domain	domain	NN
cord-258708-da6x5rxa	41	8	located	locate	VBN
cord-258708-da6x5rxa	41	9	on	on	IN
cord-258708-da6x5rxa	41	10	the	the	DT
cord-258708-da6x5rxa	41	11	cell	cell	NN
cord-258708-da6x5rxa	41	12	surface	surface	NN
cord-258708-da6x5rxa	41	13	where	where	WRB
cord-258708-da6x5rxa	41	14	it	-PRON-	PRP
cord-258708-da6x5rxa	41	15	converts	convert	VBZ
cord-258708-da6x5rxa	41	16	Ang	Ang	NNP
cord-258708-da6x5rxa	41	17	II	II	NNP
cord-258708-da6x5rxa	41	18	(	(	-LRB-
cord-258708-da6x5rxa	41	19	1	1	CD
cord-258708-da6x5rxa	41	20	-	-	SYM
cord-258708-da6x5rxa	41	21	9	9	CD
cord-258708-da6x5rxa	41	22	)	)	-RRB-
cord-258708-da6x5rxa	41	23	to	to	IN
cord-258708-da6x5rxa	41	24	Ang	Ang	NNP
cord-258708-da6x5rxa	41	25	1	1	CD
cord-258708-da6x5rxa	41	26	-	-	SYM
cord-258708-da6x5rxa	41	27	7	7	CD
cord-258708-da6x5rxa	41	28	(	(	-LRB-
cord-258708-da6x5rxa	41	29	14	14	CD
cord-258708-da6x5rxa	41	30	)	)	-RRB-
cord-258708-da6x5rxa	41	31	.	.	.
cord-258708-da6x5rxa	42	1	At	at	IN
cord-258708-da6x5rxa	42	2	this	this	DT
cord-258708-da6x5rxa	42	3	phase	phase	NN
cord-258708-da6x5rxa	42	4	negative	negative	JJ
cord-258708-da6x5rxa	42	5	regulation	regulation	NN
cord-258708-da6x5rxa	42	6	of	of	IN
cord-258708-da6x5rxa	42	7	the	the	DT
cord-258708-da6x5rxa	42	8	renin	renin	NN
cord-258708-da6x5rxa	42	9	-	-	HYPH
cord-258708-da6x5rxa	42	10	Ang	Ang	NNP
cord-258708-da6x5rxa	42	11	system	system	NN
cord-258708-da6x5rxa	42	12	,	,	,
cord-258708-da6x5rxa	42	13	with	with	IN
cord-258708-da6x5rxa	42	14	down	down	JJ
cord-258708-da6x5rxa	42	15	regulation	regulation	NN
cord-258708-da6x5rxa	42	16	of	of	IN
cord-258708-da6x5rxa	42	17	ACE2	ACE2	NNP
cord-258708-da6x5rxa	42	18	by	by	IN
cord-258708-da6x5rxa	42	19	SARS	SARS	NNP
cord-258708-da6x5rxa	42	20	-	-	HYPH
cord-258708-da6x5rxa	42	21	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	42	22	may	may	MD
cord-258708-da6x5rxa	42	23	magnify	magnify	VB
cord-258708-da6x5rxa	42	24	the	the	DT
cord-258708-da6x5rxa	42	25	cytokine	cytokine	NN
cord-258708-da6x5rxa	42	26	storm	storm	NN
cord-258708-da6x5rxa	42	27	,	,	,
cord-258708-da6x5rxa	42	28	resulting	result	VBG
cord-258708-da6x5rxa	42	29	in	in	IN
cord-258708-da6x5rxa	42	30	an	an	DT
cord-258708-da6x5rxa	42	31	overwhelming	overwhelming	JJ
cord-258708-da6x5rxa	42	32	inflammatory	inflammatory	JJ
cord-258708-da6x5rxa	42	33	response	response	NN
cord-258708-da6x5rxa	42	34	(	(	-LRB-
cord-258708-da6x5rxa	42	35	Figure	figure	NN
cord-258708-da6x5rxa	42	36	2	2	CD
cord-258708-da6x5rxa	42	37	)	)	-RRB-
cord-258708-da6x5rxa	42	38	(	(	-LRB-
cord-258708-da6x5rxa	42	39	12	12	CD
cord-258708-da6x5rxa	42	40	)	)	-RRB-
cord-258708-da6x5rxa	42	41	.	.	.
cord-258708-da6x5rxa	43	1	In	in	IN
cord-258708-da6x5rxa	43	2	order	order	NN
cord-258708-da6x5rxa	43	3	to	to	TO
cord-258708-da6x5rxa	43	4	be	be	VB
cord-258708-da6x5rxa	43	5	active	active	JJ
cord-258708-da6x5rxa	43	6	,	,	,
cord-258708-da6x5rxa	43	7	the	the	DT
cord-258708-da6x5rxa	43	8	ACE2	ACE2	NNP
cord-258708-da6x5rxa	43	9	complex	complex	NN
cord-258708-da6x5rxa	43	10	is	be	VBZ
cord-258708-da6x5rxa	43	11	assembled	assemble	VBN
cord-258708-da6x5rxa	43	12	as	as	IN
cord-258708-da6x5rxa	43	13	a	a	DT
cord-258708-da6x5rxa	43	14	stable	stable	JJ
cord-258708-da6x5rxa	43	15	dimer	dimer	NN
cord-258708-da6x5rxa	43	16	of	of	IN
cord-258708-da6x5rxa	43	17	heterodimers	heterodimer	NNS
cord-258708-da6x5rxa	43	18	through	through	IN
cord-258708-da6x5rxa	43	19	interactions	interaction	NNS
cord-258708-da6x5rxa	43	20	of	of	IN
cord-258708-da6x5rxa	43	21	the	the	DT
cord-258708-da6x5rxa	43	22	collectrin	collectrin	NN
cord-258708-da6x5rxa	43	23	-	-	HYPH
cord-258708-da6x5rxa	43	24	like	like	JJ
cord-258708-da6x5rxa	43	25	domain	domain	NN
cord-258708-da6x5rxa	43	26	of	of	IN
cord-258708-da6x5rxa	43	27	ACE2	ACE2	NNP
cord-258708-da6x5rxa	43	28	(	(	-LRB-
cord-258708-da6x5rxa	43	29	11	11	CD
cord-258708-da6x5rxa	43	30	)	)	-RRB-
cord-258708-da6x5rxa	43	31	.	.	.
cord-258708-da6x5rxa	44	1	The	the	DT
cord-258708-da6x5rxa	44	2	resultant	resultant	JJ
cord-258708-da6x5rxa	44	3	homodimer	homodimer	NN
cord-258708-da6x5rxa	44	4	is	be	VBZ
cord-258708-da6x5rxa	44	5	able	able	JJ
cord-258708-da6x5rxa	44	6	to	to	TO
cord-258708-da6x5rxa	44	7	bind	bind	VB
cord-258708-da6x5rxa	44	8	two	two	CD
cord-258708-da6x5rxa	44	9	SARS	SARS	NNP
cord-258708-da6x5rxa	44	10	-	-	HYPH
cord-258708-da6x5rxa	44	11	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	44	12	S	S	NNP
cord-258708-da6x5rxa	44	13	protein	protein	NN
cord-258708-da6x5rxa	44	14	trimers	trimer	NNS
cord-258708-da6x5rxa	44	15	simultaneously	simultaneously	RB
cord-258708-da6x5rxa	44	16	.	.	.
cord-258708-da6x5rxa	45	1	In	in	IN
cord-258708-da6x5rxa	45	2	this	this	DT
cord-258708-da6x5rxa	45	3	interaction	interaction	NN
cord-258708-da6x5rxa	45	4	,	,	,
cord-258708-da6x5rxa	45	5	the	the	DT
cord-258708-da6x5rxa	45	6	cleavage	cleavage	NN
cord-258708-da6x5rxa	45	7	of	of	IN
cord-258708-da6x5rxa	45	8	S	s	NN
cord-258708-da6x5rxa	45	9	protein	protein	NN
cord-258708-da6x5rxa	45	10	into	into	IN
cord-258708-da6x5rxa	45	11	subunits	subunit	NNS
cord-258708-da6x5rxa	45	12	,	,	,
cord-258708-da6x5rxa	45	13	S1	S1	NNP
cord-258708-da6x5rxa	45	14	and	and	CC
cord-258708-da6x5rxa	45	15	S2	S2	NNP
cord-258708-da6x5rxa	45	16	facilitates	facilitate	VBZ
cord-258708-da6x5rxa	45	17	target	target	NN
cord-258708-da6x5rxa	45	18	cell	cell	NN
cord-258708-da6x5rxa	45	19	internalization	internalization	NN
cord-258708-da6x5rxa	45	20	following	follow	VBG
cord-258708-da6x5rxa	45	21	activation	activation	NN
cord-258708-da6x5rxa	45	22	of	of	IN
cord-258708-da6x5rxa	45	23	the	the	DT
cord-258708-da6x5rxa	45	24	spike	spike	NN
cord-258708-da6x5rxa	45	25	protein	protein	NN
cord-258708-da6x5rxa	45	26	by	by	IN
cord-258708-da6x5rxa	45	27	transmembrane	transmembrane	NN
cord-258708-da6x5rxa	45	28	protease	protease	NN
cord-258708-da6x5rxa	45	29	serine	serine	NN
cord-258708-da6x5rxa	45	30	2	2	CD
cord-258708-da6x5rxa	45	31	(	(	-LRB-
cord-258708-da6x5rxa	45	32	TMPRSS2	TMPRSS2	NNP
cord-258708-da6x5rxa	45	33	)	)	-RRB-
cord-258708-da6x5rxa	45	34	(	(	-LRB-
cord-258708-da6x5rxa	45	35	12	12	CD
cord-258708-da6x5rxa	45	36	)	)	-RRB-
cord-258708-da6x5rxa	45	37	.	.	.
cord-258708-da6x5rxa	46	1	The	the	DT
cord-258708-da6x5rxa	46	2	S1	S1	NNP
cord-258708-da6x5rxa	46	3	subunit	subunit	NN
cord-258708-da6x5rxa	46	4	of	of	IN
cord-258708-da6x5rxa	46	5	S	S	NNP
cord-258708-da6x5rxa	46	6	protein	protein	NN
cord-258708-da6x5rxa	46	7	contains	contain	VBZ
cord-258708-da6x5rxa	46	8	the	the	DT
cord-258708-da6x5rxa	46	9	RBD	RBD	NNP
cord-258708-da6x5rxa	46	10	which	which	WDT
cord-258708-da6x5rxa	46	11	allows	allow	VBZ
cord-258708-da6x5rxa	46	12	coronaviruses	coronaviruse	NNS
cord-258708-da6x5rxa	46	13	to	to	TO
cord-258708-da6x5rxa	46	14	directly	directly	RB
cord-258708-da6x5rxa	46	15	bind	bind	VB
cord-258708-da6x5rxa	46	16	to	to	IN
cord-258708-da6x5rxa	46	17	the	the	DT
cord-258708-da6x5rxa	46	18	peptidase	peptidase	NN
cord-258708-da6x5rxa	46	19	domain	domain	NN
cord-258708-da6x5rxa	46	20	(	(	-LRB-
cord-258708-da6x5rxa	46	21	PD	PD	NNP
cord-258708-da6x5rxa	46	22	)	)	-RRB-
cord-258708-da6x5rxa	46	23	of	of	IN
cord-258708-da6x5rxa	46	24	ACE2	ACE2	NNP
cord-258708-da6x5rxa	46	25	(	(	-LRB-
cord-258708-da6x5rxa	46	26	11	11	CD
cord-258708-da6x5rxa	46	27	)	)	-RRB-
cord-258708-da6x5rxa	46	28	.	.	.
cord-258708-da6x5rxa	47	1	S2	S2	NNP
cord-258708-da6x5rxa	47	2	likely	likely	RB
cord-258708-da6x5rxa	47	3	plays	play	VBZ
cord-258708-da6x5rxa	47	4	a	a	DT
cord-258708-da6x5rxa	47	5	role	role	NN
cord-258708-da6x5rxa	47	6	in	in	IN
cord-258708-da6x5rxa	47	7	membrane	membrane	NN
cord-258708-da6x5rxa	47	8	fusion	fusion	NN
cord-258708-da6x5rxa	47	9	where	where	WRB
cord-258708-da6x5rxa	47	10	S1	s1	NN
cord-258708-da6x5rxa	47	11	domain	domain	NN
cord-258708-da6x5rxa	47	12	potentially	potentially	RB
cord-258708-da6x5rxa	47	13	interacts	interact	VBZ
cord-258708-da6x5rxa	47	14	with	with	IN
cord-258708-da6x5rxa	47	15	the	the	DT
cord-258708-da6x5rxa	47	16	human	human	JJ
cord-258708-da6x5rxa	47	17	CD26	CD26	NNPS
cord-258708-da6x5rxa	47	18	that	that	WDT
cord-258708-da6x5rxa	47	19	is	be	VBZ
cord-258708-da6x5rxa	47	20	involved	involve	VBN
cord-258708-da6x5rxa	47	21	in	in	IN
cord-258708-da6x5rxa	47	22	the	the	DT
cord-258708-da6x5rxa	47	23	T	t	NN
cord-258708-da6x5rxa	47	24	-	-	HYPH
cord-258708-da6x5rxa	47	25	cell	cell	NN
cord-258708-da6x5rxa	47	26	immune	immune	JJ
cord-258708-da6x5rxa	47	27	response	response	NN
cord-258708-da6x5rxa	47	28	(	(	-LRB-
cord-258708-da6x5rxa	47	29	15	15	CD
cord-258708-da6x5rxa	47	30	)	)	-RRB-
cord-258708-da6x5rxa	47	31	.	.	.
cord-258708-da6x5rxa	48	1	It	-PRON-	PRP
cord-258708-da6x5rxa	48	2	is	be	VBZ
cord-258708-da6x5rxa	48	3	speculated	speculate	VBN
cord-258708-da6x5rxa	48	4	that	that	IN
cord-258708-da6x5rxa	48	5	increased	increase	VBN
cord-258708-da6x5rxa	48	6	expression	expression	NN
cord-258708-da6x5rxa	48	7	of	of	IN
cord-258708-da6x5rxa	48	8	ACE2	ACE2	NNP
cord-258708-da6x5rxa	48	9	could	could	MD
cord-258708-da6x5rxa	48	10	potentially	potentially	RB
cord-258708-da6x5rxa	48	11	facilitate	facilitate	VB
cord-258708-da6x5rxa	48	12	SARS	SARS	NNP
cord-258708-da6x5rxa	48	13	-	-	HYPH
cord-258708-da6x5rxa	48	14	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	48	15	infection	infection	NN
cord-258708-da6x5rxa	48	16	(	(	-LRB-
cord-258708-da6x5rxa	48	17	16	16	CD
cord-258708-da6x5rxa	48	18	)	)	-RRB-
cord-258708-da6x5rxa	48	19	.	.	.
cord-258708-da6x5rxa	49	1	The	the	DT
cord-258708-da6x5rxa	49	2	SARS	SARS	NNP
cord-258708-da6x5rxa	49	3	-	-	HYPH
cord-258708-da6x5rxa	49	4	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	49	5	binding	binding	NN
cord-258708-da6x5rxa	49	6	site	site	NN
cord-258708-da6x5rxa	49	7	shows	show	VBZ
cord-258708-da6x5rxa	49	8	that	that	IN
cord-258708-da6x5rxa	49	9	it	-PRON-	PRP
cord-258708-da6x5rxa	49	10	has	have	VBZ
cord-258708-da6x5rxa	49	11	improved	improve	VBN
cord-258708-da6x5rxa	49	12	binding	bind	VBG
cord-258708-da6x5rxa	49	13	stability	stability	NN
cord-258708-da6x5rxa	49	14	,	,	,
cord-258708-da6x5rxa	49	15	and	and	CC
cord-258708-da6x5rxa	49	16	potentially	potentially	RB
cord-258708-da6x5rxa	49	17	enhanced	enhance	VBN
cord-258708-da6x5rxa	49	18	ACE2	ACE2	NNP
cord-258708-da6x5rxa	49	19	receptor	receptor	NN
cord-258708-da6x5rxa	49	20	binding	bind	VBG
cord-258708-da6x5rxa	49	21	affinity	affinity	NN
cord-258708-da6x5rxa	49	22	(	(	-LRB-
cord-258708-da6x5rxa	49	23	11	11	CD
cord-258708-da6x5rxa	49	24	)	)	-RRB-
cord-258708-da6x5rxa	49	25	.	.	.
cord-258708-da6x5rxa	50	1	Lastly	lastly	RB
cord-258708-da6x5rxa	50	2	,	,	,
cord-258708-da6x5rxa	50	3	structure	structure	NN
cord-258708-da6x5rxa	50	4	-	-	HYPH
cord-258708-da6x5rxa	50	5	based	base	VBN
cord-258708-da6x5rxa	50	6	rational	rational	JJ
cord-258708-da6x5rxa	50	7	affinity	affinity	NN
cord-258708-da6x5rxa	50	8	interaction	interaction	NN
cord-258708-da6x5rxa	50	9	to	to	IN
cord-258708-da6x5rxa	50	10	either	either	CC
cord-258708-da6x5rxa	50	11	ACE2	ACE2	NNP
cord-258708-da6x5rxa	50	12	or	or	CC
cord-258708-da6x5rxa	50	13	the	the	DT
cord-258708-da6x5rxa	50	14	S	S	NNP
cord-258708-da6x5rxa	50	15	protein	protein	NN
cord-258708-da6x5rxa	50	16	of	of	IN
cord-258708-da6x5rxa	50	17	SARS	SARS	NNP
cord-258708-da6x5rxa	50	18	-	-	HYPH
cord-258708-da6x5rxa	50	19	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	50	20	provides	provide	VBZ
cord-258708-da6x5rxa	50	21	invaluable	invaluable	JJ
cord-258708-da6x5rxa	50	22	insights	insight	NNS
cord-258708-da6x5rxa	50	23	into	into	IN
cord-258708-da6x5rxa	50	24	the	the	DT
cord-258708-da6x5rxa	50	25	molecular	molecular	JJ
cord-258708-da6x5rxa	50	26	basis	basis	NN
cord-258708-da6x5rxa	50	27	for	for	IN
cord-258708-da6x5rxa	50	28	coronavirus	coronavirus	NN
cord-258708-da6x5rxa	50	29	recognition	recognition	NN
cord-258708-da6x5rxa	50	30	,	,	,
cord-258708-da6x5rxa	50	31	and	and	CC
cord-258708-da6x5rxa	50	32	infection	infection	NN
cord-258708-da6x5rxa	50	33	.	.	.
cord-258708-da6x5rxa	51	1	These	these	DT
cord-258708-da6x5rxa	51	2	mechanisms	mechanism	NNS
cord-258708-da6x5rxa	51	3	may	may	MD
cord-258708-da6x5rxa	51	4	uncover	uncover	VB
cord-258708-da6x5rxa	51	5	a	a	DT
cord-258708-da6x5rxa	51	6	potential	potential	JJ
cord-258708-da6x5rxa	51	7	target	target	NN
cord-258708-da6x5rxa	51	8	of	of	IN
cord-258708-da6x5rxa	51	9	novel	novel	NN
cord-258708-da6x5rxa	51	10	neutralizing	neutralize	VBG
cord-258708-da6x5rxa	51	11	antibodies	antibody	NNS
cord-258708-da6x5rxa	51	12	to	to	TO
cord-258708-da6x5rxa	51	13	suppress	suppress	VB
cord-258708-da6x5rxa	51	14	infection	infection	NN
cord-258708-da6x5rxa	51	15	by	by	IN
cord-258708-da6x5rxa	51	16	new	new	JJ
cord-258708-da6x5rxa	51	17	viruses	virus	NNS
cord-258708-da6x5rxa	51	18	.	.	.
cord-258708-da6x5rxa	52	1	SARS	SARS	NNP
cord-258708-da6x5rxa	52	2	-	-	HYPH
cord-258708-da6x5rxa	52	3	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	52	4	infection	infection	NN
cord-258708-da6x5rxa	52	5	and	and	CC
cord-258708-da6x5rxa	52	6	its	-PRON-	PRP$
cord-258708-da6x5rxa	52	7	possible	possible	JJ
cord-258708-da6x5rxa	52	8	implication	implication	NN
cord-258708-da6x5rxa	52	9	to	to	IN
cord-258708-da6x5rxa	52	10	myocarditis	myocarditis	NN
cord-258708-da6x5rxa	52	11	is	be	VBZ
cord-258708-da6x5rxa	52	12	still	still	RB
cord-258708-da6x5rxa	52	13	not	not	RB
cord-258708-da6x5rxa	52	14	well	well	RB
cord-258708-da6x5rxa	52	15	documented	document	VBN
cord-258708-da6x5rxa	52	16	despite	despite	IN
cord-258708-da6x5rxa	52	17	some	some	DT
cord-258708-da6x5rxa	52	18	case	case	NN
cord-258708-da6x5rxa	52	19	report	report	NN
cord-258708-da6x5rxa	52	20	(	(	-LRB-
cord-258708-da6x5rxa	52	21	17	17	CD
cord-258708-da6x5rxa	52	22	)	)	-RRB-
cord-258708-da6x5rxa	52	23	.	.	.
cord-258708-da6x5rxa	53	1	Early	early	JJ
cord-258708-da6x5rxa	53	2	data	datum	NNS
cord-258708-da6x5rxa	53	3	indicated	indicate	VBD
cord-258708-da6x5rxa	53	4	that	that	IN
cord-258708-da6x5rxa	53	5	25	25	CD
cord-258708-da6x5rxa	53	6	%	%	NN
cord-258708-da6x5rxa	53	7	of	of	IN
cord-258708-da6x5rxa	53	8	hospitalized	hospitalize	VBN
cord-258708-da6x5rxa	53	9	,	,	,
cord-258708-da6x5rxa	53	10	and	and	CC
cord-258708-da6x5rxa	53	11	treated	treat	VBN
cord-258708-da6x5rxa	53	12	patients	patient	NNS
cord-258708-da6x5rxa	53	13	in	in	IN
cord-258708-da6x5rxa	53	14	Wuhan	Wuhan	NNP
cord-258708-da6x5rxa	53	15	had	have	VBD
cord-258708-da6x5rxa	53	16	CVD	CVD	NNP
cord-258708-da6x5rxa	53	17	(	(	-LRB-
cord-258708-da6x5rxa	53	18	18	18	CD
cord-258708-da6x5rxa	53	19	)	)	-RRB-
cord-258708-da6x5rxa	53	20	.	.	.
cord-258708-da6x5rxa	54	1	Independent	independent	JJ
cord-258708-da6x5rxa	54	2	studies	study	NNS
cord-258708-da6x5rxa	54	3	recognized	recognize	VBD
cord-258708-da6x5rxa	54	4	a	a	DT
cord-258708-da6x5rxa	54	5	primary	primary	JJ
cord-258708-da6x5rxa	54	6	role	role	NN
cord-258708-da6x5rxa	54	7	of	of	IN
cord-258708-da6x5rxa	54	8	ACE2	ACE2	NNP
cord-258708-da6x5rxa	54	9	in	in	IN
cord-258708-da6x5rxa	54	10	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	54	11	infection	infection	NN
cord-258708-da6x5rxa	54	12	(	(	-LRB-
cord-258708-da6x5rxa	54	13	19	19	CD
cord-258708-da6x5rxa	54	14	)	)	-RRB-
cord-258708-da6x5rxa	54	15	.	.	.
cord-258708-da6x5rxa	55	1	Of	of	IN
cord-258708-da6x5rxa	55	2	interest	interest	NN
cord-258708-da6x5rxa	55	3	,	,	,
cord-258708-da6x5rxa	55	4	ACE2	ACE2	NNP
cord-258708-da6x5rxa	55	5	is	be	VBZ
cord-258708-da6x5rxa	55	6	localized	localize	VBN
cord-258708-da6x5rxa	55	7	in	in	IN
cord-258708-da6x5rxa	55	8	cardiomyocytes	cardiomyocyte	NNS
cord-258708-da6x5rxa	55	9	,	,	,
cord-258708-da6x5rxa	55	10	cardiac	cardiac	JJ
cord-258708-da6x5rxa	55	11	fibroblasts	fibroblast	NNS
cord-258708-da6x5rxa	55	12	,	,	,
cord-258708-da6x5rxa	55	13	pericytes	pericyte	NNS
cord-258708-da6x5rxa	55	14	,	,	,
cord-258708-da6x5rxa	55	15	vascular	vascular	JJ
cord-258708-da6x5rxa	55	16	endothelium	endothelium	NN
cord-258708-da6x5rxa	55	17	,	,	,
cord-258708-da6x5rxa	55	18	and	and	CC
cord-258708-da6x5rxa	55	19	vascular	vascular	JJ
cord-258708-da6x5rxa	55	20	smooth	smooth	JJ
cord-258708-da6x5rxa	55	21	cells	cell	NNS
cord-258708-da6x5rxa	55	22	(	(	-LRB-
cord-258708-da6x5rxa	55	23	16	16	CD
cord-258708-da6x5rxa	55	24	,	,	,
cord-258708-da6x5rxa	55	25	20	20	CD
cord-258708-da6x5rxa	55	26	)	)	-RRB-
cord-258708-da6x5rxa	55	27	.	.	.
cord-258708-da6x5rxa	56	1	Whether	whether	IN
cord-258708-da6x5rxa	56	2	SARS	SARS	NNP
cord-258708-da6x5rxa	56	3	-	-	HYPH
cord-258708-da6x5rxa	56	4	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	56	5	can	can	MD
cord-258708-da6x5rxa	56	6	directly	directly	RB
cord-258708-da6x5rxa	56	7	proliferate	proliferate	VB
cord-258708-da6x5rxa	56	8	in	in	IN
cord-258708-da6x5rxa	56	9	the	the	DT
cord-258708-da6x5rxa	56	10	heart	heart	NN
cord-258708-da6x5rxa	56	11	is	be	VBZ
cord-258708-da6x5rxa	56	12	unidentified	unidentified	JJ
cord-258708-da6x5rxa	56	13	.	.	.
cord-258708-da6x5rxa	57	1	COVID-19	covid-19	JJ
cord-258708-da6x5rxa	57	2	patients	patient	NNS
cord-258708-da6x5rxa	57	3	with	with	IN
cord-258708-da6x5rxa	57	4	pre	pre	JJ
cord-258708-da6x5rxa	57	5	-	-	JJ
cord-258708-da6x5rxa	57	6	existing	existing	JJ
cord-258708-da6x5rxa	57	7	CVD	CVD	NNP
cord-258708-da6x5rxa	57	8	,	,	,
cord-258708-da6x5rxa	57	9	hypertension	hypertension	NN
cord-258708-da6x5rxa	57	10	,	,	,
cord-258708-da6x5rxa	57	11	and	and	CC
cord-258708-da6x5rxa	57	12	related	related	JJ
cord-258708-da6x5rxa	57	13	conditions	condition	NNS
cord-258708-da6x5rxa	57	14	experience	experience	VBP
cord-258708-da6x5rxa	57	15	disproportionately	disproportionately	RB
cord-258708-da6x5rxa	57	16	worse	bad	JJR
cord-258708-da6x5rxa	57	17	outcomes	outcome	NNS
cord-258708-da6x5rxa	57	18	(	(	-LRB-
cord-258708-da6x5rxa	57	19	21	21	CD
cord-258708-da6x5rxa	57	20	)	)	-RRB-
cord-258708-da6x5rxa	57	21	.	.	.
cord-258708-da6x5rxa	58	1	There	there	EX
cord-258708-da6x5rxa	58	2	are	be	VBP
cord-258708-da6x5rxa	58	3	a	a	DT
cord-258708-da6x5rxa	58	4	very	very	RB
cord-258708-da6x5rxa	58	5	few	few	JJ
cord-258708-da6x5rxa	58	6	pathological	pathological	JJ
cord-258708-da6x5rxa	58	7	studies	study	NNS
cord-258708-da6x5rxa	58	8	conducted	conduct	VBN
cord-258708-da6x5rxa	58	9	on	on	IN
cord-258708-da6x5rxa	58	10	the	the	DT
cord-258708-da6x5rxa	58	11	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	58	12	patients	patient	NNS
cord-258708-da6x5rxa	58	13	.	.	.
cord-258708-da6x5rxa	59	1	One	one	CD
cord-258708-da6x5rxa	59	2	of	of	IN
cord-258708-da6x5rxa	59	3	the	the	DT
cord-258708-da6x5rxa	59	4	clinical	clinical	JJ
cord-258708-da6x5rxa	59	5	features	feature	NNS
cord-258708-da6x5rxa	59	6	of	of	IN
cord-258708-da6x5rxa	59	7	patients	patient	NNS
cord-258708-da6x5rxa	59	8	infected	infect	VBN
cord-258708-da6x5rxa	59	9	with	with	IN
cord-258708-da6x5rxa	59	10	SARS	SARS	NNP
cord-258708-da6x5rxa	59	11	-	-	HYPH
cord-258708-da6x5rxa	59	12	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	59	13	included	include	VBD
cord-258708-da6x5rxa	59	14	abnormal	abnormal	JJ
cord-258708-da6x5rxa	59	15	features	feature	NNS
cord-258708-da6x5rxa	59	16	such	such	JJ
cord-258708-da6x5rxa	59	17	as	as	IN
cord-258708-da6x5rxa	59	18	acute	acute	JJ
cord-258708-da6x5rxa	59	19	cardiac	cardiac	JJ
cord-258708-da6x5rxa	59	20	injury	injury	NN
cord-258708-da6x5rxa	59	21	(	(	-LRB-
cord-258708-da6x5rxa	59	22	12	12	CD
cord-258708-da6x5rxa	59	23	%	%	NN
cord-258708-da6x5rxa	59	24	)	)	-RRB-
cord-258708-da6x5rxa	59	25	(	(	-LRB-
cord-258708-da6x5rxa	59	26	22	22	CD
cord-258708-da6x5rxa	59	27	)	)	-RRB-
cord-258708-da6x5rxa	59	28	.	.	.
cord-258708-da6x5rxa	60	1	Available	available	JJ
cord-258708-da6x5rxa	60	2	clinical	clinical	JJ
cord-258708-da6x5rxa	60	3	data	datum	NNS
cord-258708-da6x5rxa	60	4	revealed	reveal	VBD
cord-258708-da6x5rxa	60	5	that	that	IN
cord-258708-da6x5rxa	60	6	15	15	CD
cord-258708-da6x5rxa	60	7	%	%	NN
cord-258708-da6x5rxa	60	8	to	to	TO
cord-258708-da6x5rxa	60	9	30	30	CD
cord-258708-da6x5rxa	60	10	%	%	NN
cord-258708-da6x5rxa	60	11	of	of	IN
cord-258708-da6x5rxa	60	12	the	the	DT
cord-258708-da6x5rxa	60	13	COVID-19	covid-19	JJ
cord-258708-da6x5rxa	60	14	patients	patient	NNS
cord-258708-da6x5rxa	60	15	present	present	JJ
cord-258708-da6x5rxa	60	16	with	with	IN
cord-258708-da6x5rxa	60	17	hypertension	hypertension	NN
cord-258708-da6x5rxa	60	18	,	,	,
cord-258708-da6x5rxa	60	19	and	and	CC
cord-258708-da6x5rxa	60	20	2.5	2.5	CD
cord-258708-da6x5rxa	60	21	%	%	NN
cord-258708-da6x5rxa	60	22	to	to	TO
cord-258708-da6x5rxa	60	23	15	15	CD
cord-258708-da6x5rxa	60	24	%	%	NN
cord-258708-da6x5rxa	60	25	with	with	IN
cord-258708-da6x5rxa	60	26	coronary	coronary	JJ
cord-258708-da6x5rxa	60	27	heart	heart	NN
cord-258708-da6x5rxa	60	28	disease	disease	NN
cord-258708-da6x5rxa	60	29	(	(	-LRB-
cord-258708-da6x5rxa	60	30	18	18	CD
cord-258708-da6x5rxa	60	31	,	,	,
cord-258708-da6x5rxa	60	32	23	23	CD
cord-258708-da6x5rxa	60	33	)	)	-RRB-
cord-258708-da6x5rxa	60	34	.	.	.
cord-258708-da6x5rxa	61	1	Viral	viral	JJ
cord-258708-da6x5rxa	61	2	involvement	involvement	NN
cord-258708-da6x5rxa	61	3	of	of	IN
cord-258708-da6x5rxa	61	4	cardiomyocytes	cardiomyocyte	NNS
cord-258708-da6x5rxa	61	5	,	,	,
cord-258708-da6x5rxa	61	6	and	and	CC
cord-258708-da6x5rxa	61	7	the	the	DT
cord-258708-da6x5rxa	61	8	effect	effect	NN
cord-258708-da6x5rxa	61	9	of	of	IN
cord-258708-da6x5rxa	61	10	systemic	systemic	JJ
cord-258708-da6x5rxa	61	11	inflammation	inflammation	NN
cord-258708-da6x5rxa	61	12	seem	seem	VBP
cord-258708-da6x5rxa	61	13	to	to	TO
cord-258708-da6x5rxa	61	14	be	be	VB
cord-258708-da6x5rxa	61	15	the	the	DT
cord-258708-da6x5rxa	61	16	most	most	RBS
cord-258708-da6x5rxa	61	17	common	common	JJ
cord-258708-da6x5rxa	61	18	mechanisms	mechanism	NNS
cord-258708-da6x5rxa	61	19	responsible	responsible	JJ
cord-258708-da6x5rxa	61	20	for	for	IN
cord-258708-da6x5rxa	61	21	cardiac	cardiac	JJ
cord-258708-da6x5rxa	61	22	injury	injury	NN
cord-258708-da6x5rxa	61	23	(	(	-LRB-
cord-258708-da6x5rxa	61	24	20	20	CD
cord-258708-da6x5rxa	61	25	)	)	-RRB-
cord-258708-da6x5rxa	62	1	(	(	-LRB-
cord-258708-da6x5rxa	62	2	Figure	figure	NN
cord-258708-da6x5rxa	62	3	2	2	CD
cord-258708-da6x5rxa	62	4	)	)	-RRB-
cord-258708-da6x5rxa	62	5	.	.	.
cord-258708-da6x5rxa	63	1	Thus	thus	RB
cord-258708-da6x5rxa	63	2	,	,	,
cord-258708-da6x5rxa	63	3	suggesting	suggest	VBG
cord-258708-da6x5rxa	63	4	that	that	IN
cord-258708-da6x5rxa	63	5	inflammation	inflammation	NN
cord-258708-da6x5rxa	63	6	may	may	MD
cord-258708-da6x5rxa	63	7	be	be	VB
cord-258708-da6x5rxa	63	8	a	a	DT
cord-258708-da6x5rxa	63	9	potential	potential	JJ
cord-258708-da6x5rxa	63	10	mechanism	mechanism	NN
cord-258708-da6x5rxa	63	11	for	for	IN
cord-258708-da6x5rxa	63	12	myocardial	myocardial	JJ
cord-258708-da6x5rxa	63	13	injury	injury	NN
cord-258708-da6x5rxa	63	14	.	.	.
cord-258708-da6x5rxa	64	1	Various	various	JJ
cord-258708-da6x5rxa	64	2	diseases	disease	NNS
cord-258708-da6x5rxa	64	3	including	include	VBG
cord-258708-da6x5rxa	64	4	heart	heart	NN
cord-258708-da6x5rxa	64	5	failure	failure	NN
cord-258708-da6x5rxa	64	6	,	,	,
cord-258708-da6x5rxa	64	7	hypertension	hypertension	NN
cord-258708-da6x5rxa	64	8	,	,	,
cord-258708-da6x5rxa	64	9	and	and	CC
cord-258708-da6x5rxa	64	10	diabetes	diabetes	NN
cord-258708-da6x5rxa	64	11	are	be	VBP
cord-258708-da6x5rxa	64	12	characterized	characterize	VBN
cord-258708-da6x5rxa	64	13	by	by	IN
cord-258708-da6x5rxa	64	14	a	a	DT
cord-258708-da6x5rxa	64	15	relative	relative	JJ
cord-258708-da6x5rxa	64	16	ACE2-deficient	ACE2-deficient	NNP
cord-258708-da6x5rxa	64	17	state	state	NN
cord-258708-da6x5rxa	64	18	(	(	-LRB-
cord-258708-da6x5rxa	64	19	24	24	CD
cord-258708-da6x5rxa	64	20	)	)	-RRB-
cord-258708-da6x5rxa	64	21	.	.	.
cord-258708-da6x5rxa	65	1	Genetic	genetic	JJ
cord-258708-da6x5rxa	65	2	data	data	NN
cord-258708-da6x5rxa	65	3	shows	show	VBZ
cord-258708-da6x5rxa	65	4	that	that	IN
cord-258708-da6x5rxa	65	5	ACE2	ACE2	NNP
cord-258708-da6x5rxa	65	6	is	be	VBZ
cord-258708-da6x5rxa	65	7	an	an	DT
cord-258708-da6x5rxa	65	8	essential	essential	JJ
cord-258708-da6x5rxa	65	9	regulator	regulator	NN
cord-258708-da6x5rxa	65	10	of	of	IN
cord-258708-da6x5rxa	65	11	heart	heart	NN
cord-258708-da6x5rxa	65	12	function	function	NN
cord-258708-da6x5rxa	65	13	in	in	IN
cord-258708-da6x5rxa	65	14	vivo	vivo	NNP
cord-258708-da6x5rxa	65	15	(	(	-LRB-
cord-258708-da6x5rxa	65	16	25	25	CD
cord-258708-da6x5rxa	65	17	)	)	-RRB-
cord-258708-da6x5rxa	65	18	.	.	.
cord-258708-da6x5rxa	66	1	Activation	activation	NN
cord-258708-da6x5rxa	66	2	of	of	IN
cord-258708-da6x5rxa	66	3	renin	renin	NN
cord-258708-da6x5rxa	66	4	-	-	HYPH
cord-258708-da6x5rxa	66	5	Ang	Ang	NNP
cord-258708-da6x5rxa	66	6	system	system	NN
cord-258708-da6x5rxa	66	7	,	,	,
cord-258708-da6x5rxa	66	8	and	and	CC
cord-258708-da6x5rxa	66	9	the	the	DT
cord-258708-da6x5rxa	66	10	downregulation	downregulation	NN
cord-258708-da6x5rxa	66	11	of	of	IN
cord-258708-da6x5rxa	66	12	ACE2	ACE2	NNP
cord-258708-da6x5rxa	66	13	expression	expression	NN
cord-258708-da6x5rxa	66	14	play	play	VBP
cord-258708-da6x5rxa	66	15	a	a	DT
cord-258708-da6x5rxa	66	16	key	key	JJ
cord-258708-da6x5rxa	66	17	role	role	NN
cord-258708-da6x5rxa	66	18	in	in	IN
cord-258708-da6x5rxa	66	19	several	several	JJ
cord-258708-da6x5rxa	66	20	diseases	disease	NNS
cord-258708-da6x5rxa	66	21	including	include	VBG
cord-258708-da6x5rxa	66	22	CV	cv	NN
cord-258708-da6x5rxa	66	23	pathologies	pathology	NNS
cord-258708-da6x5rxa	66	24	(	(	-LRB-
cord-258708-da6x5rxa	66	25	Figure	figure	NN
cord-258708-da6x5rxa	66	26	2	2	CD
cord-258708-da6x5rxa	66	27	)	)	-RRB-
cord-258708-da6x5rxa	66	28	(	(	-LRB-
cord-258708-da6x5rxa	66	29	16	16	CD
cord-258708-da6x5rxa	66	30	)	)	-RRB-
cord-258708-da6x5rxa	66	31	.	.	.
cord-258708-da6x5rxa	67	1	Accordingly	accordingly	RB
cord-258708-da6x5rxa	67	2	,	,	,
cord-258708-da6x5rxa	67	3	ACE2	ACE2	NNP
cord-258708-da6x5rxa	67	4	blockade	blockade	NN
cord-258708-da6x5rxa	67	5	delayed	delay	VBN
cord-258708-da6x5rxa	67	6	CV	cv	NN
cord-258708-da6x5rxa	67	7	damage	damage	NN
cord-258708-da6x5rxa	67	8	in	in	IN
cord-258708-da6x5rxa	67	9	diabetic	diabetic	JJ
cord-258708-da6x5rxa	67	10	patients	patient	NNS
cord-258708-da6x5rxa	67	11	(	(	-LRB-
cord-258708-da6x5rxa	67	12	16	16	CD
cord-258708-da6x5rxa	67	13	,	,	,
cord-258708-da6x5rxa	67	14	26	26	CD
cord-258708-da6x5rxa	67	15	)	)	-RRB-
cord-258708-da6x5rxa	67	16	.	.	.
cord-258708-da6x5rxa	68	1	Experimental	experimental	JJ
cord-258708-da6x5rxa	68	2	evidence	evidence	NN
cord-258708-da6x5rxa	68	3	suggested	suggest	VBD
cord-258708-da6x5rxa	68	4	a	a	DT
cord-258708-da6x5rxa	68	5	beneficial	beneficial	JJ
cord-258708-da6x5rxa	68	6	role	role	NN
cord-258708-da6x5rxa	68	7	of	of	IN
cord-258708-da6x5rxa	68	8	ACE2	ACE2	NNP
cord-258708-da6x5rxa	68	9	in	in	IN
cord-258708-da6x5rxa	68	10	CV	CV	NNP
cord-258708-da6x5rxa	68	11	function	function	NN
cord-258708-da6x5rxa	68	12	(	(	-LRB-
cord-258708-da6x5rxa	68	13	14	14	CD
cord-258708-da6x5rxa	68	14	)	)	-RRB-
cord-258708-da6x5rxa	68	15	.	.	.
cord-258708-da6x5rxa	69	1	Genetic	genetic	JJ
cord-258708-da6x5rxa	69	2	manipulation	manipulation	NN
cord-258708-da6x5rxa	69	3	of	of	IN
cord-258708-da6x5rxa	69	4	ACE2	ACE2	NNP
cord-258708-da6x5rxa	69	5	expression	expression	NN
cord-258708-da6x5rxa	69	6	points	point	VBZ
cord-258708-da6x5rxa	69	7	to	to	IN
cord-258708-da6x5rxa	69	8	the	the	DT
cord-258708-da6x5rxa	69	9	possible	possible	JJ
cord-258708-da6x5rxa	69	10	significance	significance	NN
cord-258708-da6x5rxa	69	11	of	of	IN
cord-258708-da6x5rxa	69	12	this	this	DT
cord-258708-da6x5rxa	69	13	enzyme	enzyme	NN
cord-258708-da6x5rxa	69	14	in	in	IN
cord-258708-da6x5rxa	69	15	cardiac	cardiac	JJ
cord-258708-da6x5rxa	69	16	function	function	NN
cord-258708-da6x5rxa	69	17	,	,	,
cord-258708-da6x5rxa	69	18	and	and	CC
cord-258708-da6x5rxa	69	19	vulnerability	vulnerability	NN
cord-258708-da6x5rxa	69	20	to	to	IN
cord-258708-da6x5rxa	69	21	heart	heart	NN
cord-258708-da6x5rxa	69	22	failure	failure	NN
cord-258708-da6x5rxa	69	23	(	(	-LRB-
cord-258708-da6x5rxa	69	24	14	14	CD
cord-258708-da6x5rxa	69	25	,	,	,
cord-258708-da6x5rxa	69	26	19	19	CD
cord-258708-da6x5rxa	69	27	)	)	-RRB-
cord-258708-da6x5rxa	69	28	.	.	.
cord-258708-da6x5rxa	70	1	In	in	IN
cord-258708-da6x5rxa	70	2	the	the	DT
cord-258708-da6x5rxa	70	3	established	establish	VBN
cord-258708-da6x5rxa	70	4	heart	heart	NN
cord-258708-da6x5rxa	70	5	failure	failure	NN
cord-258708-da6x5rxa	70	6	,	,	,
cord-258708-da6x5rxa	70	7	expression	expression	NN
cord-258708-da6x5rxa	70	8	of	of	IN
cord-258708-da6x5rxa	70	9	ACE2	ACE2	NNP
cord-258708-da6x5rxa	70	10	on	on	IN
cord-258708-da6x5rxa	70	11	the	the	DT
cord-258708-da6x5rxa	70	12	cell	cell	NN
cord-258708-da6x5rxa	70	13	surface	surface	NN
cord-258708-da6x5rxa	70	14	is	be	VBZ
cord-258708-da6x5rxa	70	15	downregulated	downregulate	VBN
cord-258708-da6x5rxa	70	16	;	;	:
cord-258708-da6x5rxa	70	17	however	however	RB
cord-258708-da6x5rxa	70	18	,	,	,
cord-258708-da6x5rxa	70	19	there	there	EX
cord-258708-da6x5rxa	70	20	is	be	VBZ
cord-258708-da6x5rxa	70	21	an	an	DT
cord-258708-da6x5rxa	70	22	increase	increase	NN
cord-258708-da6x5rxa	70	23	in	in	IN
cord-258708-da6x5rxa	70	24	circulating	circulate	VBG
cord-258708-da6x5rxa	70	25	ACE2	ACE2	NNP
cord-258708-da6x5rxa	70	26	levels	level	NNS
cord-258708-da6x5rxa	70	27	,	,	,
cord-258708-da6x5rxa	70	28	and	and	CC
cord-258708-da6x5rxa	70	29	activity	activity	NN
cord-258708-da6x5rxa	70	30	when	when	WRB
cord-258708-da6x5rxa	70	31	compared	compare	VBN
cord-258708-da6x5rxa	70	32	to	to	IN
cord-258708-da6x5rxa	70	33	healthy	healthy	JJ
cord-258708-da6x5rxa	70	34	individuals	individual	NNS
cord-258708-da6x5rxa	70	35	(	(	-LRB-
cord-258708-da6x5rxa	70	36	14	14	CD
cord-258708-da6x5rxa	70	37	,	,	,
cord-258708-da6x5rxa	70	38	27	27	CD
cord-258708-da6x5rxa	70	39	)	)	-RRB-
cord-258708-da6x5rxa	70	40	.	.	.
cord-258708-da6x5rxa	71	1	It	-PRON-	PRP
cord-258708-da6x5rxa	71	2	is	be	VBZ
cord-258708-da6x5rxa	71	3	assumed	assume	VBN
cord-258708-da6x5rxa	71	4	that	that	IN
cord-258708-da6x5rxa	71	5	shedding	shed	VBG
cord-258708-da6x5rxa	71	6	of	of	IN
cord-258708-da6x5rxa	71	7	the	the	DT
cord-258708-da6x5rxa	71	8	membrane	membrane	NN
cord-258708-da6x5rxa	71	9	-	-	HYPH
cord-258708-da6x5rxa	71	10	bound	bind	VBN
cord-258708-da6x5rxa	71	11	ACE2	ACE2	NNP
cord-258708-da6x5rxa	71	12	may	may	MD
cord-258708-da6x5rxa	71	13	be	be	VB
cord-258708-da6x5rxa	71	14	responsible	responsible	JJ
cord-258708-da6x5rxa	71	15	for	for	IN
cord-258708-da6x5rxa	71	16	the	the	DT
cord-258708-da6x5rxa	71	17	increased	increase	VBN
cord-258708-da6x5rxa	71	18	circulating	circulate	VBG
cord-258708-da6x5rxa	71	19	endogenous	endogenous	JJ
cord-258708-da6x5rxa	71	20	ACE2	ACE2	NNP
cord-258708-da6x5rxa	71	21	activity	activity	NN
cord-258708-da6x5rxa	71	22	in	in	IN
cord-258708-da6x5rxa	71	23	COVID-19	covid-19	JJ
cord-258708-da6x5rxa	71	24	patients	patient	NNS
cord-258708-da6x5rxa	71	25	(	(	-LRB-
cord-258708-da6x5rxa	71	26	28	28	CD
cord-258708-da6x5rxa	71	27	)	)	-RRB-
cord-258708-da6x5rxa	71	28	.	.	.
cord-258708-da6x5rxa	72	1	Circulating	circulate	VBG
cord-258708-da6x5rxa	72	2	levels	level	NNS
cord-258708-da6x5rxa	72	3	of	of	IN
cord-258708-da6x5rxa	72	4	soluble	soluble	JJ
cord-258708-da6x5rxa	72	5	ACE2	ACE2	NNP
cord-258708-da6x5rxa	72	6	are	be	VBP
cord-258708-da6x5rxa	72	7	usually	usually	RB
cord-258708-da6x5rxa	72	8	low	low	JJ
cord-258708-da6x5rxa	72	9	to	to	IN
cord-258708-da6x5rxa	72	10	nondetectable	nondetectable	JJ
cord-258708-da6x5rxa	72	11	.	.	.
cord-258708-da6x5rxa	73	1	Soluble	soluble	JJ
cord-258708-da6x5rxa	73	2	ACE2	ACE2	NNP
cord-258708-da6x5rxa	73	3	would	would	MD
cord-258708-da6x5rxa	73	4	therefore	therefore	RB
cord-258708-da6x5rxa	73	5	not	not	RB
cord-258708-da6x5rxa	73	6	sufficiently	sufficiently	RB
cord-258708-da6x5rxa	73	7	sequester	sequester	VB
cord-258708-da6x5rxa	73	8	SARS	SARS	NNP
cord-258708-da6x5rxa	73	9	-	-	HYPH
cord-258708-da6x5rxa	73	10	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	73	11	in	in	IN
cord-258708-da6x5rxa	73	12	the	the	DT
cord-258708-da6x5rxa	73	13	circulation	circulation	NN
cord-258708-da6x5rxa	73	14	to	to	TO
cord-258708-da6x5rxa	73	15	prevent	prevent	VB
cord-258708-da6x5rxa	73	16	viral	viral	JJ
cord-258708-da6x5rxa	73	17	dissemination	dissemination	NN
cord-258708-da6x5rxa	73	18	(	(	-LRB-
cord-258708-da6x5rxa	73	19	19	19	CD
cord-258708-da6x5rxa	73	20	)	)	-RRB-
cord-258708-da6x5rxa	73	21	.	.	.
cord-258708-da6x5rxa	74	1	However	however	RB
cord-258708-da6x5rxa	74	2	,	,	,
cord-258708-da6x5rxa	74	3	the	the	DT
cord-258708-da6x5rxa	74	4	extent	extent	NN
cord-258708-da6x5rxa	74	5	to	to	TO
cord-258708-da6x5rxa	74	6	which	which	WDT
cord-258708-da6x5rxa	74	7	soluble	soluble	JJ
cord-258708-da6x5rxa	74	8	ACE2	ACE2	NNP
cord-258708-da6x5rxa	74	9	would	would	MD
cord-258708-da6x5rxa	74	10	compete	compete	VB
cord-258708-da6x5rxa	74	11	for	for	IN
cord-258708-da6x5rxa	74	12	SARS	SARS	NNP
cord-258708-da6x5rxa	74	13	-	-	HYPH
cord-258708-da6x5rxa	74	14	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	74	15	binding	bind	VBG
cord-258708-da6x5rxa	74	16	to	to	TO
cord-258708-da6x5rxa	74	17	reduce	reduce	VB
cord-258708-da6x5rxa	74	18	viremia	viremia	NN
cord-258708-da6x5rxa	74	19	infection	infection	NN
cord-258708-da6x5rxa	74	20	and	and	CC
cord-258708-da6x5rxa	74	21	alleviate	alleviate	VB
cord-258708-da6x5rxa	74	22	tissue	tissue	NN
cord-258708-da6x5rxa	74	23	injury	injury	NN
cord-258708-da6x5rxa	74	24	is	be	VBZ
cord-258708-da6x5rxa	74	25	unknown	unknown	JJ
cord-258708-da6x5rxa	74	26	.	.	.
cord-258708-da6x5rxa	75	1	The	the	DT
cord-258708-da6x5rxa	75	2	occurrence	occurrence	NN
cord-258708-da6x5rxa	75	3	of	of	IN
cord-258708-da6x5rxa	75	4	fulminant	fulminant	JJ
cord-258708-da6x5rxa	75	5	myocarditis	myocarditis	NN
cord-258708-da6x5rxa	75	6	,	,	,
cord-258708-da6x5rxa	75	7	and	and	CC
cord-258708-da6x5rxa	75	8	cardiogenic	cardiogenic	JJ
cord-258708-da6x5rxa	75	9	shock	shock	NN
cord-258708-da6x5rxa	75	10	seems	seem	VBZ
cord-258708-da6x5rxa	75	11	low	low	JJ
cord-258708-da6x5rxa	75	12	in	in	IN
cord-258708-da6x5rxa	75	13	patients	patient	NNS
cord-258708-da6x5rxa	75	14	with	with	IN
cord-258708-da6x5rxa	75	15	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	75	16	(	(	-LRB-
cord-258708-da6x5rxa	75	17	29	29	CD
cord-258708-da6x5rxa	75	18	,	,	,
cord-258708-da6x5rxa	75	19	30	30	CD
cord-258708-da6x5rxa	75	20	)	)	-RRB-
cord-258708-da6x5rxa	75	21	.	.	.
cord-258708-da6x5rxa	76	1	Despite	despite	IN
cord-258708-da6x5rxa	76	2	this	this	DT
cord-258708-da6x5rxa	76	3	,	,	,
cord-258708-da6x5rxa	76	4	a	a	DT
cord-258708-da6x5rxa	76	5	predisposition	predisposition	NN
cord-258708-da6x5rxa	76	6	to	to	IN
cord-258708-da6x5rxa	76	7	acute	acute	JJ
cord-258708-da6x5rxa	76	8	cardiac	cardiac	JJ
cord-258708-da6x5rxa	76	9	complications	complication	NNS
cord-258708-da6x5rxa	76	10	related	relate	VBN
cord-258708-da6x5rxa	76	11	to	to	IN
cord-258708-da6x5rxa	76	12	underlying	underlying	JJ
cord-258708-da6x5rxa	76	13	atherosclerotic	atherosclerotic	JJ
cord-258708-da6x5rxa	76	14	CVD	CVD	NNP
cord-258708-da6x5rxa	76	15	may	may	MD
cord-258708-da6x5rxa	76	16	significantly	significantly	RB
cord-258708-da6x5rxa	76	17	increase	increase	VB
cord-258708-da6x5rxa	76	18	the	the	DT
cord-258708-da6x5rxa	76	19	severity	severity	NN
cord-258708-da6x5rxa	76	20	of	of	IN
cord-258708-da6x5rxa	76	21	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	76	22	in	in	IN
cord-258708-da6x5rxa	76	23	vulnerable	vulnerable	JJ
cord-258708-da6x5rxa	76	24	individuals	individual	NNS
cord-258708-da6x5rxa	76	25	(	(	-LRB-
cord-258708-da6x5rxa	76	26	30	30	CD
cord-258708-da6x5rxa	76	27	)	)	-RRB-
cord-258708-da6x5rxa	76	28	.	.	.
cord-258708-da6x5rxa	77	1	The	the	DT
cord-258708-da6x5rxa	77	2	exact	exact	JJ
cord-258708-da6x5rxa	77	3	mechanism	mechanism	NN
cord-258708-da6x5rxa	77	4	of	of	IN
cord-258708-da6x5rxa	77	5	cardiac	cardiac	JJ
cord-258708-da6x5rxa	77	6	involvement	involvement	NN
cord-258708-da6x5rxa	77	7	in	in	IN
cord-258708-da6x5rxa	77	8	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	77	9	is	be	VBZ
cord-258708-da6x5rxa	77	10	still	still	RB
cord-258708-da6x5rxa	77	11	under	under	IN
cord-258708-da6x5rxa	77	12	investigation	investigation	NN
cord-258708-da6x5rxa	77	13	.	.	.
cord-258708-da6x5rxa	78	1	As	as	IN
cord-258708-da6x5rxa	78	2	presented	present	VBN
cord-258708-da6x5rxa	78	3	above	above	RB
cord-258708-da6x5rxa	78	4	,	,	,
cord-258708-da6x5rxa	78	5	one	one	CD
cord-258708-da6x5rxa	78	6	potential	potential	JJ
cord-258708-da6x5rxa	78	7	mechanism	mechanism	NN
cord-258708-da6x5rxa	78	8	is	be	VBZ
cord-258708-da6x5rxa	78	9	direct	direct	JJ
cord-258708-da6x5rxa	78	10	myocardial	myocardial	JJ
cord-258708-da6x5rxa	78	11	involvement	involvement	NN
cord-258708-da6x5rxa	78	12	mediated	mediate	VBN
cord-258708-da6x5rxa	78	13	by	by	IN
cord-258708-da6x5rxa	78	14	ACE2	ACE2	NNP
cord-258708-da6x5rxa	78	15	.	.	.
cord-258708-da6x5rxa	79	1	Other	other	JJ
cord-258708-da6x5rxa	79	2	mechanisms	mechanism	NNS
cord-258708-da6x5rxa	79	3	of	of	IN
cord-258708-da6x5rxa	79	4	COVID-19	covid-19	JJ
cord-258708-da6x5rxa	79	5	morbidity	morbidity	NN
cord-258708-da6x5rxa	79	6	related	relate	VBN
cord-258708-da6x5rxa	79	7	to	to	IN
cord-258708-da6x5rxa	79	8	cardiac	cardiac	JJ
cord-258708-da6x5rxa	79	9	complications	complication	NNS
cord-258708-da6x5rxa	79	10	are	be	VBP
cord-258708-da6x5rxa	79	11	discussed	discuss	VBN
cord-258708-da6x5rxa	79	12	below	below	RB
cord-258708-da6x5rxa	79	13	.	.	.
cord-258708-da6x5rxa	80	1	Renin	renin	NN
cord-258708-da6x5rxa	80	2	-	-	HYPH
cord-258708-da6x5rxa	80	3	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	80	4	-	-	HYPH
cord-258708-da6x5rxa	80	5	aldosterone	aldosterone	NN
cord-258708-da6x5rxa	80	6	system	system	NN
cord-258708-da6x5rxa	80	7	(	(	-LRB-
cord-258708-da6x5rxa	80	8	RAAS	RAAS	NNP
cord-258708-da6x5rxa	80	9	)	)	-RRB-
cord-258708-da6x5rxa	81	1	inhibitors	inhibitor	NNS
cord-258708-da6x5rxa	81	2	are	be	VBP
cord-258708-da6x5rxa	81	3	predominantly	predominantly	RB
cord-258708-da6x5rxa	81	4	including	include	VBG
cord-258708-da6x5rxa	81	5	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	81	6	-	-	HYPH
cord-258708-da6x5rxa	81	7	converting	convert	VBG
cord-258708-da6x5rxa	81	8	enzyme	enzyme	NN
cord-258708-da6x5rxa	81	9	(	(	-LRB-
cord-258708-da6x5rxa	81	10	ACE	ACE	NNP
cord-258708-da6x5rxa	81	11	)	)	-RRB-
cord-258708-da6x5rxa	81	12	inhibitors	inhibitor	NNS
cord-258708-da6x5rxa	81	13	,	,	,
cord-258708-da6x5rxa	81	14	and	and	CC
cord-258708-da6x5rxa	81	15	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	81	16	II	II	NNP
cord-258708-da6x5rxa	81	17	-	-	HYPH
cord-258708-da6x5rxa	81	18	receptor	receptor	NN
cord-258708-da6x5rxa	81	19	blockers	blocker	NNS
cord-258708-da6x5rxa	81	20	(	(	-LRB-
cord-258708-da6x5rxa	81	21	ARBs	arb	NNS
cord-258708-da6x5rxa	81	22	)	)	-RRB-
cord-258708-da6x5rxa	81	23	(	(	-LRB-
cord-258708-da6x5rxa	81	24	Figure	figure	NN
cord-258708-da6x5rxa	81	25	2	2	CD
cord-258708-da6x5rxa	81	26	)	)	-RRB-
cord-258708-da6x5rxa	81	27	.	.	.
cord-258708-da6x5rxa	82	1	RAAS	RAAS	NNP
cord-258708-da6x5rxa	82	2	inhibitors	inhibitor	NNS
cord-258708-da6x5rxa	82	3	are	be	VBP
cord-258708-da6x5rxa	82	4	often	often	RB
cord-258708-da6x5rxa	82	5	prescribed	prescribe	VBN
cord-258708-da6x5rxa	82	6	to	to	TO
cord-258708-da6x5rxa	82	7	treat	treat	VB
cord-258708-da6x5rxa	82	8	patients	patient	NNS
cord-258708-da6x5rxa	82	9	with	with	IN
cord-258708-da6x5rxa	82	10	hypertension	hypertension	NN
cord-258708-da6x5rxa	82	11	,	,	,
cord-258708-da6x5rxa	82	12	or	or	CC
cord-258708-da6x5rxa	82	13	diabetes	diabetes	NN
cord-258708-da6x5rxa	82	14	who	who	WP
cord-258708-da6x5rxa	82	15	are	be	VBP
cord-258708-da6x5rxa	82	16	infected	infect	VBN
cord-258708-da6x5rxa	82	17	with	with	IN
cord-258708-da6x5rxa	82	18	SARS	SARS	NNP
cord-258708-da6x5rxa	82	19	-	-	HYPH
cord-258708-da6x5rxa	82	20	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	82	21	(	(	-LRB-
cord-258708-da6x5rxa	82	22	31	31	CD
cord-258708-da6x5rxa	82	23	)	)	-RRB-
cord-258708-da6x5rxa	82	24	.	.	.
cord-258708-da6x5rxa	83	1	Data	datum	NNS
cord-258708-da6x5rxa	83	2	from	from	IN
cord-258708-da6x5rxa	83	3	experimental	experimental	JJ
cord-258708-da6x5rxa	83	4	mouse	mouse	NN
cord-258708-da6x5rxa	83	5	models	model	NNS
cord-258708-da6x5rxa	83	6	,	,	,
cord-258708-da6x5rxa	83	7	revealed	reveal	VBD
cord-258708-da6x5rxa	83	8	that	that	IN
cord-258708-da6x5rxa	83	9	injection	injection	NN
cord-258708-da6x5rxa	83	10	of	of	IN
cord-258708-da6x5rxa	83	11	SARS	SARS	NNP
cord-258708-da6x5rxa	83	12	-	-	HYPH
cord-258708-da6x5rxa	83	13	CoV-1	CoV-1	NNP
cord-258708-da6x5rxa	83	14	induced	induce	VBD
cord-258708-da6x5rxa	83	15	acute	acute	JJ
cord-258708-da6x5rxa	83	16	lung	lung	NN
cord-258708-da6x5rxa	83	17	injury	injury	NN
cord-258708-da6x5rxa	83	18	,	,	,
cord-258708-da6x5rxa	83	19	which	which	WDT
cord-258708-da6x5rxa	83	20	is	be	VBZ
cord-258708-da6x5rxa	83	21	limited	limit	VBN
cord-258708-da6x5rxa	83	22	by	by	IN
cord-258708-da6x5rxa	83	23	blocking	block	VBG
cord-258708-da6x5rxa	83	24	the	the	DT
cord-258708-da6x5rxa	83	25	RA	RA	NNP
cord-258708-da6x5rxa	83	26	pathway	pathway	NN
cord-258708-da6x5rxa	83	27	(	(	-LRB-
cord-258708-da6x5rxa	83	28	27	27	CD
cord-258708-da6x5rxa	83	29	)	)	-RRB-
cord-258708-da6x5rxa	83	30	.	.	.
cord-258708-da6x5rxa	84	1	Intravenous	intravenous	JJ
cord-258708-da6x5rxa	84	2	recombinant	recombinant	JJ
cord-258708-da6x5rxa	84	3	human	human	JJ
cord-258708-da6x5rxa	84	4	ACE2	ACE2	NNP
cord-258708-da6x5rxa	84	5	(	(	-LRB-
cord-258708-da6x5rxa	84	6	rhACE2	rhACE2	NNP
cord-258708-da6x5rxa	84	7	;	;	:
cord-258708-da6x5rxa	84	8	APN01	APN01	NNP
cord-258708-da6x5rxa	84	9	,	,	,
cord-258708-da6x5rxa	84	10	GSK2586881	GSK2586881	NNP
cord-258708-da6x5rxa	84	11	)	)	-RRB-
cord-258708-da6x5rxa	84	12	was	be	VBD
cord-258708-da6x5rxa	84	13	given	give	VBN
cord-258708-da6x5rxa	84	14	to	to	IN
cord-258708-da6x5rxa	84	15	healthy	healthy	JJ
cord-258708-da6x5rxa	84	16	subjects	subject	NNS
cord-258708-da6x5rxa	84	17	in	in	IN
cord-258708-da6x5rxa	84	18	a	a	DT
cord-258708-da6x5rxa	84	19	randomized	randomized	JJ
cord-258708-da6x5rxa	84	20	clinical	clinical	JJ
cord-258708-da6x5rxa	84	21	trial	trial	NN
cord-258708-da6x5rxa	84	22	phase	phase	NN
cord-258708-da6x5rxa	84	23	2	2	CD
cord-258708-da6x5rxa	85	1	(	(	-LRB-
cord-258708-da6x5rxa	85	2	ClinicalTrials.gov	ClinicalTrials.gov	NNP
cord-258708-da6x5rxa	85	3	number	number	NN
cord-258708-da6x5rxa	85	4	NCT01597635	NCT01597635	NNP
cord-258708-da6x5rxa	85	5	)	)	-RRB-
cord-258708-da6x5rxa	85	6	safely	safely	RB
cord-258708-da6x5rxa	85	7	reduced	reduce	VBN
cord-258708-da6x5rxa	85	8	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	85	9	II	ii	CD
cord-258708-da6x5rxa	85	10	levels	level	NNS
cord-258708-da6x5rxa	85	11	,	,	,
cord-258708-da6x5rxa	85	12	is	be	VBZ
cord-258708-da6x5rxa	85	13	evaluated	evaluate	VBN
cord-258708-da6x5rxa	85	14	in	in	IN
cord-258708-da6x5rxa	85	15	humans	human	NNS
cord-258708-da6x5rxa	85	16	with	with	IN
cord-258708-da6x5rxa	85	17	acute	acute	JJ
cord-258708-da6x5rxa	85	18	respiratory	respiratory	JJ
cord-258708-da6x5rxa	85	19	distress	distress	NN
cord-258708-da6x5rxa	85	20	syndrome	syndrome	NN
cord-258708-da6x5rxa	85	21	.	.	.
cord-258708-da6x5rxa	86	1	In	in	IN
cord-258708-da6x5rxa	86	2	this	this	DT
cord-258708-da6x5rxa	86	3	trial	trial	NN
cord-258708-da6x5rxa	86	4	,	,	,
cord-258708-da6x5rxa	86	5	the	the	DT
cord-258708-da6x5rxa	86	6	observed	observed	JJ
cord-258708-da6x5rxa	86	7	restoration	restoration	NN
cord-258708-da6x5rxa	86	8	of	of	IN
cord-258708-da6x5rxa	86	9	ACE2	ACE2	NNP
cord-258708-da6x5rxa	86	10	through	through	IN
cord-258708-da6x5rxa	86	11	the	the	DT
cord-258708-da6x5rxa	86	12	administration	administration	NN
cord-258708-da6x5rxa	86	13	of	of	IN
cord-258708-da6x5rxa	86	14	(	(	-LRB-
cord-258708-da6x5rxa	86	15	GSK2586881	GSK2586881	NNP
cord-258708-da6x5rxa	86	16	)	)	-RRB-
cord-258708-da6x5rxa	86	17	,	,	,
cord-258708-da6x5rxa	86	18	appeared	appear	VBD
cord-258708-da6x5rxa	86	19	to	to	TO
cord-258708-da6x5rxa	86	20	attenuate	attenuate	VB
cord-258708-da6x5rxa	86	21	acute	acute	JJ
cord-258708-da6x5rxa	86	22	lung	lung	NN
cord-258708-da6x5rxa	86	23	injury	injury	NN
cord-258708-da6x5rxa	86	24	(	(	-LRB-
cord-258708-da6x5rxa	86	25	32	32	CD
cord-258708-da6x5rxa	86	26	)	)	-RRB-
cord-258708-da6x5rxa	86	27	.	.	.
cord-258708-da6x5rxa	87	1	However	however	RB
cord-258708-da6x5rxa	87	2	,	,	,
cord-258708-da6x5rxa	87	3	this	this	DT
cord-258708-da6x5rxa	87	4	study	study	NN
cord-258708-da6x5rxa	87	5	was	be	VBD
cord-258708-da6x5rxa	87	6	not	not	RB
cord-258708-da6x5rxa	87	7	adequately	adequately	RB
cord-258708-da6x5rxa	87	8	powered	power	VBN
cord-258708-da6x5rxa	87	9	to	to	TO
cord-258708-da6x5rxa	87	10	determine	determine	VB
cord-258708-da6x5rxa	87	11	changes	change	NNS
cord-258708-da6x5rxa	87	12	in	in	IN
cord-258708-da6x5rxa	87	13	acute	acute	JJ
cord-258708-da6x5rxa	87	14	physiology	physiology	NN
cord-258708-da6x5rxa	87	15	or	or	CC
cord-258708-da6x5rxa	87	16	clinical	clinical	JJ
cord-258708-da6x5rxa	87	17	outcomes	outcome	NNS
cord-258708-da6x5rxa	87	18	(	(	-LRB-
cord-258708-da6x5rxa	87	19	33	33	CD
cord-258708-da6x5rxa	87	20	)	)	-RRB-
cord-258708-da6x5rxa	87	21	.	.	.
cord-258708-da6x5rxa	88	1	Furthermore	furthermore	RB
cord-258708-da6x5rxa	88	2	,	,	,
cord-258708-da6x5rxa	88	3	in	in	IN
cord-258708-da6x5rxa	88	4	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	88	5	as	as	IN
cord-258708-da6x5rxa	88	6	with	with	IN
cord-258708-da6x5rxa	88	7	SARS	SARS	NNP
cord-258708-da6x5rxa	88	8	-	-	HYPH
cord-258708-da6x5rxa	88	9	CoV	CoV	NNP
cord-258708-da6x5rxa	88	10	,	,	,
cord-258708-da6x5rxa	88	11	higher	high	JJR
cord-258708-da6x5rxa	88	12	ACE2	ACE2	NNP
cord-258708-da6x5rxa	88	13	expression	expression	NN
cord-258708-da6x5rxa	88	14	might	may	MD
cord-258708-da6x5rxa	88	15	lead	lead	VB
cord-258708-da6x5rxa	88	16	to	to	IN
cord-258708-da6x5rxa	88	17	a	a	DT
cord-258708-da6x5rxa	88	18	higher	high	JJR
cord-258708-da6x5rxa	88	19	risk	risk	NN
cord-258708-da6x5rxa	88	20	of	of	IN
cord-258708-da6x5rxa	88	21	SARS	SARS	NNP
cord-258708-da6x5rxa	88	22	-	-	HYPH
cord-258708-da6x5rxa	88	23	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	88	24	infection	infection	NN
cord-258708-da6x5rxa	88	25	(	(	-LRB-
cord-258708-da6x5rxa	88	26	28	28	CD
cord-258708-da6x5rxa	88	27	,	,	,
cord-258708-da6x5rxa	88	28	34	34	CD
cord-258708-da6x5rxa	88	29	)	)	-RRB-
cord-258708-da6x5rxa	88	30	.	.	.
cord-258708-da6x5rxa	89	1	Therefore	therefore	RB
cord-258708-da6x5rxa	89	2	,	,	,
cord-258708-da6x5rxa	89	3	targeted	target	VBN
cord-258708-da6x5rxa	89	4	disruption	disruption	NN
cord-258708-da6x5rxa	89	5	of	of	IN
cord-258708-da6x5rxa	89	6	ACE2	ACE2	NNP
cord-258708-da6x5rxa	89	7	in	in	IN
cord-258708-da6x5rxa	89	8	mice	mouse	NNS
cord-258708-da6x5rxa	89	9	caused	cause	VBD
cord-258708-da6x5rxa	89	10	the	the	DT
cord-258708-da6x5rxa	89	11	development	development	NN
cord-258708-da6x5rxa	89	12	of	of	IN
cord-258708-da6x5rxa	89	13	abnormal	abnormal	JJ
cord-258708-da6x5rxa	89	14	heart	heart	NN
cord-258708-da6x5rxa	89	15	function	function	NN
cord-258708-da6x5rxa	89	16	(	(	-LRB-
cord-258708-da6x5rxa	89	17	25	25	CD
cord-258708-da6x5rxa	89	18	)	)	-RRB-
cord-258708-da6x5rxa	89	19	.	.	.
cord-258708-da6x5rxa	90	1	Yet	yet	RB
cord-258708-da6x5rxa	90	2	,	,	,
cord-258708-da6x5rxa	90	3	increasing	increase	VBG
cord-258708-da6x5rxa	90	4	the	the	DT
cord-258708-da6x5rxa	90	5	expression	expression	NN
cord-258708-da6x5rxa	90	6	of	of	IN
cord-258708-da6x5rxa	90	7	ACE2	ACE2	NNP
cord-258708-da6x5rxa	90	8	may	may	MD
cord-258708-da6x5rxa	90	9	prevent	prevent	VB
cord-258708-da6x5rxa	90	10	,	,	,
cord-258708-da6x5rxa	90	11	and	and	CC
cord-258708-da6x5rxa	90	12	reverse	reverse	VB
cord-258708-da6x5rxa	90	13	heart	heart	NN
cord-258708-da6x5rxa	90	14	failure	failure	NN
cord-258708-da6x5rxa	90	15	.	.	.
cord-258708-da6x5rxa	91	1	Consequently	consequently	RB
cord-258708-da6x5rxa	91	2	,	,	,
cord-258708-da6x5rxa	91	3	a	a	DT
cord-258708-da6x5rxa	91	4	therapeutic	therapeutic	JJ
cord-258708-da6x5rxa	91	5	approach	approach	NN
cord-258708-da6x5rxa	91	6	that	that	WDT
cord-258708-da6x5rxa	91	7	will	will	MD
cord-258708-da6x5rxa	91	8	amplify	amplify	VB
cord-258708-da6x5rxa	91	9	the	the	DT
cord-258708-da6x5rxa	91	10	ACE2-Ang	ACE2-Ang	NNP
cord-258708-da6x5rxa	91	11	(	(	-LRB-
cord-258708-da6x5rxa	91	12	1	1	CD
cord-258708-da6x5rxa	91	13	-	-	SYM
cord-258708-da6x5rxa	91	14	7	7	CD
cord-258708-da6x5rxa	91	15	)	)	-RRB-
cord-258708-da6x5rxa	91	16	axis	axis	NN
cord-258708-da6x5rxa	91	17	could	could	MD
cord-258708-da6x5rxa	91	18	provide	provide	VB
cord-258708-da6x5rxa	91	19	further	further	JJ
cord-258708-da6x5rxa	91	20	protection	protection	NN
cord-258708-da6x5rxa	91	21	against	against	IN
cord-258708-da6x5rxa	91	22	the	the	DT
cord-258708-da6x5rxa	91	23	progression	progression	NN
cord-258708-da6x5rxa	91	24	of	of	IN
cord-258708-da6x5rxa	91	25	CVD	CVD	NNP
cord-258708-da6x5rxa	91	26	(	(	-LRB-
cord-258708-da6x5rxa	91	27	35	35	CD
cord-258708-da6x5rxa	91	28	)	)	-RRB-
cord-258708-da6x5rxa	91	29	.	.	.
cord-258708-da6x5rxa	92	1	Basing	base	VBG
cord-258708-da6x5rxa	92	2	on	on	IN
cord-258708-da6x5rxa	92	3	these	these	DT
cord-258708-da6x5rxa	92	4	data	datum	NNS
cord-258708-da6x5rxa	92	5	,	,	,
cord-258708-da6x5rxa	92	6	some	some	DT
cord-258708-da6x5rxa	92	7	authors	author	NNS
cord-258708-da6x5rxa	92	8	have	have	VBP
cord-258708-da6x5rxa	92	9	proposed	propose	VBN
cord-258708-da6x5rxa	92	10	an	an	DT
cord-258708-da6x5rxa	92	11	association	association	NN
cord-258708-da6x5rxa	92	12	between	between	IN
cord-258708-da6x5rxa	92	13	the	the	DT
cord-258708-da6x5rxa	92	14	use	use	NN
cord-258708-da6x5rxa	92	15	of	of	IN
cord-258708-da6x5rxa	92	16	RAAS	RAAS	NNP
cord-258708-da6x5rxa	92	17	inhibitors	inhibitor	NNS
cord-258708-da6x5rxa	92	18	and	and	CC
cord-258708-da6x5rxa	92	19	Covid-19	covid-19	NN
cord-258708-da6x5rxa	92	20	.	.	.
cord-258708-da6x5rxa	93	1	Nevertheless	nevertheless	RB
cord-258708-da6x5rxa	93	2	,	,	,
cord-258708-da6x5rxa	93	3	this	this	DT
cord-258708-da6x5rxa	93	4	association	association	NN
cord-258708-da6x5rxa	93	5	has	have	VBZ
cord-258708-da6x5rxa	93	6	been	be	VBN
cord-258708-da6x5rxa	93	7	rejected	reject	VBN
cord-258708-da6x5rxa	93	8	due	due	IN
cord-258708-da6x5rxa	93	9	to	to	IN
cord-258708-da6x5rxa	93	10	the	the	DT
cord-258708-da6x5rxa	93	11	lack	lack	NN
cord-258708-da6x5rxa	93	12	of	of	IN
cord-258708-da6x5rxa	93	13	evidence	evidence	NN
cord-258708-da6x5rxa	93	14	on	on	IN
cord-258708-da6x5rxa	93	15	the	the	DT
cord-258708-da6x5rxa	93	16	efficacy	efficacy	NN
cord-258708-da6x5rxa	93	17	of	of	IN
cord-258708-da6x5rxa	93	18	this	this	DT
cord-258708-da6x5rxa	93	19	approach	approach	NN
cord-258708-da6x5rxa	93	20	in	in	IN
cord-258708-da6x5rxa	93	21	reducing	reduce	VBG
cord-258708-da6x5rxa	93	22	adverse	adverse	JJ
cord-258708-da6x5rxa	93	23	outcomes	outcome	NNS
cord-258708-da6x5rxa	93	24	in	in	IN
cord-258708-da6x5rxa	93	25	Covid-19	covid-19	NN
cord-258708-da6x5rxa	93	26	patients	patient	NNS
cord-258708-da6x5rxa	93	27	(	(	-LRB-
cord-258708-da6x5rxa	93	28	36	36	CD
cord-258708-da6x5rxa	93	29	,	,	,
cord-258708-da6x5rxa	93	30	37	37	CD
cord-258708-da6x5rxa	93	31	)	)	-RRB-
cord-258708-da6x5rxa	93	32	.	.	.
cord-258708-da6x5rxa	94	1	Even	even	RB
cord-258708-da6x5rxa	94	2	if	if	IN
cord-258708-da6x5rxa	94	3	RAAS	RAAS	NNP
cord-258708-da6x5rxa	94	4	inhibitors	inhibitor	NNS
cord-258708-da6x5rxa	94	5	modify	modify	VBP
cord-258708-da6x5rxa	94	6	ACE2	ACE2	NNP
cord-258708-da6x5rxa	94	7	levels	level	NNS
cord-258708-da6x5rxa	94	8	or	or	CC
cord-258708-da6x5rxa	94	9	activity	activity	NN
cord-258708-da6x5rxa	94	10	(	(	-LRB-
cord-258708-da6x5rxa	94	11	or	or	CC
cord-258708-da6x5rxa	94	12	both	both	DT
cord-258708-da6x5rxa	94	13	)	)	-RRB-
cord-258708-da6x5rxa	94	14	in	in	IN
cord-258708-da6x5rxa	94	15	target	target	NN
cord-258708-da6x5rxa	94	16	tissue	tissue	NN
cord-258708-da6x5rxa	94	17	,	,	,
cord-258708-da6x5rxa	94	18	there	there	EX
cord-258708-da6x5rxa	94	19	are	be	VBP
cord-258708-da6x5rxa	94	20	not	not	RB
cord-258708-da6x5rxa	94	21	enough	enough	JJ
cord-258708-da6x5rxa	94	22	clinical	clinical	JJ
cord-258708-da6x5rxa	94	23	reports	report	NNS
cord-258708-da6x5rxa	94	24	to	to	TO
cord-258708-da6x5rxa	94	25	indicate	indicate	VB
cord-258708-da6x5rxa	94	26	whether	whether	IN
cord-258708-da6x5rxa	94	27	this	this	DT
cord-258708-da6x5rxa	94	28	would	would	MD
cord-258708-da6x5rxa	94	29	in	in	IN
cord-258708-da6x5rxa	94	30	turn	turn	NN
cord-258708-da6x5rxa	94	31	facilitate	facilitate	VB
cord-258708-da6x5rxa	94	32	greater	great	JJR
cord-258708-da6x5rxa	94	33	entry	entry	NN
cord-258708-da6x5rxa	94	34	of	of	IN
cord-258708-da6x5rxa	94	35	SARS	SARS	NNP
cord-258708-da6x5rxa	94	36	-	-	HYPH
cord-258708-da6x5rxa	94	37	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	94	38	proteins	protein	NNS
cord-258708-da6x5rxa	94	39	.	.	.
cord-258708-da6x5rxa	95	1	Further	further	JJ
cord-258708-da6x5rxa	95	2	mechanistic	mechanistic	JJ
cord-258708-da6x5rxa	95	3	studies	study	NNS
cord-258708-da6x5rxa	95	4	are	be	VBP
cord-258708-da6x5rxa	95	5	required	require	VBN
cord-258708-da6x5rxa	95	6	to	to	TO
cord-258708-da6x5rxa	95	7	better	better	RB
cord-258708-da6x5rxa	95	8	define	define	VB
cord-258708-da6x5rxa	95	9	the	the	DT
cord-258708-da6x5rxa	95	10	unique	unique	JJ
cord-258708-da6x5rxa	95	11	interplay	interplay	NN
cord-258708-da6x5rxa	95	12	between	between	IN
cord-258708-da6x5rxa	95	13	SARS	SARS	NNP
cord-258708-da6x5rxa	95	14	-	-	HYPH
cord-258708-da6x5rxa	95	15	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	95	16	and	and	CC
cord-258708-da6x5rxa	95	17	the	the	DT
cord-258708-da6x5rxa	95	18	RAAS	RAAS	NNP
cord-258708-da6x5rxa	95	19	network	network	NN
cord-258708-da6x5rxa	95	20	(	(	-LRB-
cord-258708-da6x5rxa	95	21	38	38	CD
cord-258708-da6x5rxa	95	22	)	)	-RRB-
cord-258708-da6x5rxa	95	23	.	.	.
cord-258708-da6x5rxa	96	1	SARS	SARS	NNP
cord-258708-da6x5rxa	96	2	-	-	HYPH
cord-258708-da6x5rxa	96	3	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	96	4	seems	seem	VBZ
cord-258708-da6x5rxa	96	5	to	to	TO
cord-258708-da6x5rxa	96	6	damage	damage	VB
cord-258708-da6x5rxa	96	7	the	the	DT
cord-258708-da6x5rxa	96	8	heart	heart	NN
cord-258708-da6x5rxa	96	9	's	's	POS
cord-258708-da6x5rxa	96	10	muscle	muscle	NN
cord-258708-da6x5rxa	96	11	tissue	tissue	NN
cord-258708-da6x5rxa	96	12	and	and	CC
cord-258708-da6x5rxa	96	13	can	can	MD
cord-258708-da6x5rxa	96	14	cause	cause	VB
cord-258708-da6x5rxa	96	15	myocarditis	myocarditis	NN
cord-258708-da6x5rxa	96	16	(	(	-LRB-
cord-258708-da6x5rxa	96	17	39	39	CD
cord-258708-da6x5rxa	96	18	)	)	-RRB-
cord-258708-da6x5rxa	96	19	.	.	.
cord-258708-da6x5rxa	97	1	Accordingly	accordingly	RB
cord-258708-da6x5rxa	97	2	,	,	,
cord-258708-da6x5rxa	97	3	after	after	IN
cord-258708-da6x5rxa	97	4	SARS	SARS	NNP
cord-258708-da6x5rxa	97	5	-	-	HYPH
cord-258708-da6x5rxa	97	6	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	97	7	infection	infection	NN
cord-258708-da6x5rxa	97	8	various	various	JJ
cord-258708-da6x5rxa	97	9	cases	case	NNS
cord-258708-da6x5rxa	97	10	of	of	IN
cord-258708-da6x5rxa	97	11	severe	severe	JJ
cord-258708-da6x5rxa	97	12	myocarditis	myocarditis	NN
cord-258708-da6x5rxa	97	13	with	with	IN
cord-258708-da6x5rxa	97	14	reduced	reduce	VBN
cord-258708-da6x5rxa	97	15	systolic	systolic	JJ
cord-258708-da6x5rxa	97	16	function	function	NN
cord-258708-da6x5rxa	97	17	have	have	VBP
cord-258708-da6x5rxa	97	18	been	be	VBN
cord-258708-da6x5rxa	97	19	reported	report	VBN
cord-258708-da6x5rxa	97	20	(	(	-LRB-
cord-258708-da6x5rxa	97	21	17	17	CD
cord-258708-da6x5rxa	97	22	)	)	-RRB-
cord-258708-da6x5rxa	97	23	.	.	.
cord-258708-da6x5rxa	98	1	Although	although	IN
cord-258708-da6x5rxa	98	2	the	the	DT
cord-258708-da6x5rxa	98	3	mechanisms	mechanism	NNS
cord-258708-da6x5rxa	98	4	of	of	IN
cord-258708-da6x5rxa	98	5	myocardial	myocardial	JJ
cord-258708-da6x5rxa	98	6	involvement	involvement	NN
cord-258708-da6x5rxa	98	7	in	in	IN
cord-258708-da6x5rxa	98	8	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	98	9	are	be	VBP
cord-258708-da6x5rxa	98	10	still	still	RB
cord-258708-da6x5rxa	98	11	under	under	IN
cord-258708-da6x5rxa	98	12	investigation	investigation	NN
cord-258708-da6x5rxa	98	13	,	,	,
cord-258708-da6x5rxa	98	14	they	-PRON-	PRP
cord-258708-da6x5rxa	98	15	probably	probably	RB
cord-258708-da6x5rxa	98	16	include	include	VBP
cord-258708-da6x5rxa	98	17	direct	direct	JJ
cord-258708-da6x5rxa	98	18	viral	viral	JJ
cord-258708-da6x5rxa	98	19	infection	infection	NN
cord-258708-da6x5rxa	98	20	,	,	,
cord-258708-da6x5rxa	98	21	hypoxiainduced	hypoxiainduced	JJ
cord-258708-da6x5rxa	98	22	apoptosis	apoptosis	NN
cord-258708-da6x5rxa	98	23	,	,	,
cord-258708-da6x5rxa	98	24	and	and	CC
cord-258708-da6x5rxa	98	25	cytokine	cytokine	JJ
cord-258708-da6x5rxa	98	26	storm	storm	NN
cord-258708-da6x5rxa	98	27	-	-	HYPH
cord-258708-da6x5rxa	98	28	related	relate	VBN
cord-258708-da6x5rxa	98	29	cell	cell	NN
cord-258708-da6x5rxa	98	30	damage	damage	NN
cord-258708-da6x5rxa	98	31	in	in	IN
cord-258708-da6x5rxa	98	32	the	the	DT
cord-258708-da6x5rxa	98	33	body	body	NN
cord-258708-da6x5rxa	98	34	(	(	-LRB-
cord-258708-da6x5rxa	98	35	4	4	CD
cord-258708-da6x5rxa	98	36	)	)	-RRB-
cord-258708-da6x5rxa	98	37	.	.	.
cord-258708-da6x5rxa	99	1	Excessive	excessive	JJ
cord-258708-da6x5rxa	99	2	inflammation	inflammation	NN
cord-258708-da6x5rxa	99	3	(	(	-LRB-
cord-258708-da6x5rxa	99	4	IL6	il6	NN
cord-258708-da6x5rxa	99	5	,	,	,
cord-258708-da6x5rxa	99	6	TNFα	TNFα	NNP
cord-258708-da6x5rxa	99	7	,	,	,
cord-258708-da6x5rxa	99	8	and	and	CC
cord-258708-da6x5rxa	99	9	IL-1	IL-1	NNP
cord-258708-da6x5rxa	99	10	)	)	-RRB-
cord-258708-da6x5rxa	99	11	can	can	MD
cord-258708-da6x5rxa	99	12	further	further	RB
cord-258708-da6x5rxa	99	13	modulate	modulate	VB
cord-258708-da6x5rxa	99	14	the	the	DT
cord-258708-da6x5rxa	99	15	function	function	NN
cord-258708-da6x5rxa	99	16	of	of	IN
cord-258708-da6x5rxa	99	17	several	several	JJ
cord-258708-da6x5rxa	99	18	cardiomyocyte	cardiomyocyte	NNP
cord-258708-da6x5rxa	99	19	ion	ion	NN
cord-258708-da6x5rxa	99	20	channels	channel	NNS
cord-258708-da6x5rxa	99	21	,	,	,
cord-258708-da6x5rxa	99	22	specifically	specifically	RB
cord-258708-da6x5rxa	99	23	K+	K+	NNP
cord-258708-da6x5rxa	99	24	and	and	CC
cord-258708-da6x5rxa	99	25	Ca++	Ca++	NNP
cord-258708-da6x5rxa	99	26	channels	channel	NNS
cord-258708-da6x5rxa	99	27	,	,	,
cord-258708-da6x5rxa	99	28	leading	lead	VBG
cord-258708-da6x5rxa	99	29	to	to	IN
cord-258708-da6x5rxa	99	30	inflammatory	inflammatory	JJ
cord-258708-da6x5rxa	99	31	cardiac	cardiac	JJ
cord-258708-da6x5rxa	99	32	channelopathies	channelopathie	NNS
cord-258708-da6x5rxa	99	33	(	(	-LRB-
cord-258708-da6x5rxa	99	34	40	40	CD
cord-258708-da6x5rxa	99	35	)	)	-RRB-
cord-258708-da6x5rxa	99	36	.	.	.
cord-258708-da6x5rxa	100	1	Excessive	excessive	JJ
cord-258708-da6x5rxa	100	2	intracellular	intracellular	JJ
cord-258708-da6x5rxa	100	3	calcium	calcium	NN
cord-258708-da6x5rxa	100	4	promotes	promote	VBZ
cord-258708-da6x5rxa	100	5	cardiomyocyte	cardiomyocyte	NN
cord-258708-da6x5rxa	100	6	apoptosis	apoptosis	NN
cord-258708-da6x5rxa	100	7	(	(	-LRB-
cord-258708-da6x5rxa	100	8	41	41	CD
cord-258708-da6x5rxa	100	9	)	)	-RRB-
cord-258708-da6x5rxa	100	10	.	.	.
cord-258708-da6x5rxa	101	1	Moreover	moreover	RB
cord-258708-da6x5rxa	101	2	,	,	,
cord-258708-da6x5rxa	101	3	myocardial	myocardial	JJ
cord-258708-da6x5rxa	101	4	injury	injury	NN
cord-258708-da6x5rxa	101	5	might	may	MD
cord-258708-da6x5rxa	101	6	represent	represent	VB
cord-258708-da6x5rxa	101	7	a	a	DT
cord-258708-da6x5rxa	101	8	main	main	JJ
cord-258708-da6x5rxa	101	9	driver	driver	NN
cord-258708-da6x5rxa	101	10	of	of	IN
cord-258708-da6x5rxa	101	11	enhanced	enhanced	JJ
cord-258708-da6x5rxa	101	12	arrhythmic	arrhythmic	JJ
cord-258708-da6x5rxa	101	13	risk	risk	NN
cord-258708-da6x5rxa	101	14	in	in	IN
cord-258708-da6x5rxa	101	15	these	these	DT
cord-258708-da6x5rxa	101	16	patients	patient	NNS
cord-258708-da6x5rxa	101	17	(	(	-LRB-
cord-258708-da6x5rxa	101	18	42	42	CD
cord-258708-da6x5rxa	101	19	)	)	-RRB-
cord-258708-da6x5rxa	101	20	.	.	.
cord-258708-da6x5rxa	102	1	With	with	IN
cord-258708-da6x5rxa	102	2	the	the	DT
cord-258708-da6x5rxa	102	3	constantly	constantly	RB
cord-258708-da6x5rxa	102	4	evolving	evolve	VBG
cord-258708-da6x5rxa	102	5	recognition	recognition	NN
cord-258708-da6x5rxa	102	6	of	of	IN
cord-258708-da6x5rxa	102	7	the	the	DT
cord-258708-da6x5rxa	102	8	interplay	interplay	NN
cord-258708-da6x5rxa	102	9	between	between	IN
cord-258708-da6x5rxa	102	10	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	102	11	and	and	CC
cord-258708-da6x5rxa	102	12	the	the	DT
cord-258708-da6x5rxa	102	13	CV	cv	NN
cord-258708-da6x5rxa	102	14	system	system	NN
cord-258708-da6x5rxa	102	15	,	,	,
cord-258708-da6x5rxa	102	16	available	available	JJ
cord-258708-da6x5rxa	102	17	clinical	clinical	JJ
cord-258708-da6x5rxa	102	18	data	datum	NNS
cord-258708-da6x5rxa	102	19	have	have	VBP
cord-258708-da6x5rxa	102	20	shown	show	VBN
cord-258708-da6x5rxa	102	21	that	that	IN
cord-258708-da6x5rxa	102	22	between	between	IN
cord-258708-da6x5rxa	102	23	8	8	CD
cord-258708-da6x5rxa	102	24	-	-	SYM
cord-258708-da6x5rxa	102	25	28	28	CD
cord-258708-da6x5rxa	102	26	%	%	NN
cord-258708-da6x5rxa	102	27	of	of	IN
cord-258708-da6x5rxa	102	28	patients	patient	NNS
cord-258708-da6x5rxa	102	29	with	with	IN
cord-258708-da6x5rxa	102	30	COVID-19	covid-19	JJ
cord-258708-da6x5rxa	102	31	infections	infection	NNS
cord-258708-da6x5rxa	102	32	will	will	MD
cord-258708-da6x5rxa	102	33	manifest	manifest	VB
cord-258708-da6x5rxa	102	34	acute	acute	JJ
cord-258708-da6x5rxa	102	35	cardiac	cardiac	JJ
cord-258708-da6x5rxa	102	36	injury	injury	NN
cord-258708-da6x5rxa	102	37	.	.	.
cord-258708-da6x5rxa	103	1	This	this	DT
cord-258708-da6x5rxa	103	2	condition	condition	NN
cord-258708-da6x5rxa	103	3	is	be	VBZ
cord-258708-da6x5rxa	103	4	assessed	assess	VBN
cord-258708-da6x5rxa	103	5	by	by	IN
cord-258708-da6x5rxa	103	6	increase	increase	NN
cord-258708-da6x5rxa	103	7	in	in	IN
cord-258708-da6x5rxa	103	8	cardiac	cardiac	JJ
cord-258708-da6x5rxa	103	9	biomarkers	biomarker	NNS
cord-258708-da6x5rxa	103	10	release	release	VBP
cord-258708-da6x5rxa	103	11	such	such	JJ
cord-258708-da6x5rxa	103	12	as	as	IN
cord-258708-da6x5rxa	103	13	elevated	elevated	JJ
cord-258708-da6x5rxa	103	14	troponin	troponin	NN
cord-258708-da6x5rxa	103	15	I	i	NN
cord-258708-da6x5rxa	103	16	(	(	-LRB-
cord-258708-da6x5rxa	103	17	TnT	TnT	NNP
cord-258708-da6x5rxa	103	18	)	)	-RRB-
cord-258708-da6x5rxa	103	19	,	,	,
cord-258708-da6x5rxa	103	20	N	n	CD
cord-258708-da6x5rxa	103	21	-	-	HYPH
cord-258708-da6x5rxa	103	22	terminal	terminal	JJ
cord-258708-da6x5rxa	103	23	pro	pro	JJ
cord-258708-da6x5rxa	103	24	-	-	JJ
cord-258708-da6x5rxa	103	25	brain	brain	JJ
cord-258708-da6x5rxa	103	26	natriuretic	natriuretic	JJ
cord-258708-da6x5rxa	103	27	peptide	peptide	NN
cord-258708-da6x5rxa	103	28	(	(	-LRB-
cord-258708-da6x5rxa	103	29	NT	NT	NNP
cord-258708-da6x5rxa	103	30	-	-	HYPH
cord-258708-da6x5rxa	103	31	proBNP	probnp	NN
cord-258708-da6x5rxa	103	32	)	)	-RRB-
cord-258708-da6x5rxa	103	33	or	or	CC
cord-258708-da6x5rxa	103	34	Btype	Btype	NNP
cord-258708-da6x5rxa	103	35	natriuretic	natriuretic	JJ
cord-258708-da6x5rxa	103	36	peptide	peptide	NN
cord-258708-da6x5rxa	103	37	(	(	-LRB-
cord-258708-da6x5rxa	103	38	BNP	BNP	NNP
cord-258708-da6x5rxa	103	39	)	)	-RRB-
cord-258708-da6x5rxa	103	40	(	(	-LRB-
cord-258708-da6x5rxa	103	41	Table	table	NN
cord-258708-da6x5rxa	103	42	2	2	CD
cord-258708-da6x5rxa	103	43	)	)	-RRB-
cord-258708-da6x5rxa	103	44	(	(	-LRB-
cord-258708-da6x5rxa	103	45	22	22	CD
cord-258708-da6x5rxa	103	46	,	,	,
cord-258708-da6x5rxa	103	47	43	43	CD
cord-258708-da6x5rxa	103	48	,	,	,
cord-258708-da6x5rxa	103	49	44	44	CD
cord-258708-da6x5rxa	103	50	)	)	-RRB-
cord-258708-da6x5rxa	103	51	.	.	.
cord-258708-da6x5rxa	104	1	Evidence	evidence	NN
cord-258708-da6x5rxa	104	2	of	of	IN
cord-258708-da6x5rxa	104	3	myocardial	myocardial	JJ
cord-258708-da6x5rxa	104	4	injury	injury	NN
cord-258708-da6x5rxa	104	5	was	be	VBD
cord-258708-da6x5rxa	104	6	recommended	recommend	VBN
cord-258708-da6x5rxa	104	7	on	on	IN
cord-258708-da6x5rxa	104	8	the	the	DT
cord-258708-da6x5rxa	104	9	basis	basis	NN
cord-258708-da6x5rxa	104	10	that	that	IN
cord-258708-da6x5rxa	104	11	TnT	TnT	NNP
cord-258708-da6x5rxa	104	12	elevation	elevation	NN
cord-258708-da6x5rxa	104	13	in	in	IN
cord-258708-da6x5rxa	104	14	patients	patient	NNS
cord-258708-da6x5rxa	104	15	with	with	IN
cord-258708-da6x5rxa	104	16	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	104	17	is	be	VBZ
cord-258708-da6x5rxa	104	18	significantly	significantly	RB
cord-258708-da6x5rxa	104	19	associated	associate	VBN
cord-258708-da6x5rxa	104	20	with	with	IN
cord-258708-da6x5rxa	104	21	fatal	fatal	JJ
cord-258708-da6x5rxa	104	22	outcomes	outcome	NNS
cord-258708-da6x5rxa	104	23	(	(	-LRB-
cord-258708-da6x5rxa	104	24	45	45	CD
cord-258708-da6x5rxa	104	25	)	)	-RRB-
cord-258708-da6x5rxa	104	26	.	.	.
cord-258708-da6x5rxa	105	1	Numerous	numerous	JJ
cord-258708-da6x5rxa	105	2	mechanisms	mechanism	NNS
cord-258708-da6x5rxa	105	3	may	may	MD
cord-258708-da6x5rxa	105	4	elucidate	elucidate	VB
cord-258708-da6x5rxa	105	5	this	this	DT
cord-258708-da6x5rxa	105	6	phenomenon	phenomenon	NN
cord-258708-da6x5rxa	105	7	mostly	mostly	RB
cord-258708-da6x5rxa	105	8	viral	viral	JJ
cord-258708-da6x5rxa	105	9	myocarditis	myocarditis	NN
cord-258708-da6x5rxa	105	10	,	,	,
cord-258708-da6x5rxa	105	11	cytokine	cytokine	NN
cord-258708-da6x5rxa	105	12	-	-	HYPH
cord-258708-da6x5rxa	105	13	driven	drive	VBN
cord-258708-da6x5rxa	105	14	myocardial	myocardial	JJ
cord-258708-da6x5rxa	105	15	injury	injury	NN
cord-258708-da6x5rxa	105	16	,	,	,
cord-258708-da6x5rxa	105	17	and	and	CC
cord-258708-da6x5rxa	105	18	microangiopathy	microangiopathy	NNP
cord-258708-da6x5rxa	105	19	(	(	-LRB-
cord-258708-da6x5rxa	105	20	Table	Table	NNP
cord-258708-da6x5rxa	105	21	2	2	CD
cord-258708-da6x5rxa	105	22	)	)	-RRB-
cord-258708-da6x5rxa	105	23	.	.	.
cord-258708-da6x5rxa	106	1	Yet	yet	RB
cord-258708-da6x5rxa	106	2	,	,	,
cord-258708-da6x5rxa	106	3	none	none	NN
cord-258708-da6x5rxa	106	4	of	of	IN
cord-258708-da6x5rxa	106	5	these	these	DT
cord-258708-da6x5rxa	106	6	mechanisms	mechanism	NNS
cord-258708-da6x5rxa	106	7	have	have	VBP
cord-258708-da6x5rxa	106	8	been	be	VBN
cord-258708-da6x5rxa	106	9	recognised	recognise	VBN
cord-258708-da6x5rxa	106	10	to	to	TO
cord-258708-da6x5rxa	106	11	be	be	VB
cord-258708-da6x5rxa	106	12	the	the	DT
cord-258708-da6x5rxa	106	13	key	key	JJ
cord-258708-da6x5rxa	106	14	driver	driver	NN
cord-258708-da6x5rxa	106	15	of	of	IN
cord-258708-da6x5rxa	106	16	troponin	troponin	JJ
cord-258708-da6x5rxa	106	17	rise	rise	NN
cord-258708-da6x5rxa	106	18	and/or	and/or	CC
cord-258708-da6x5rxa	106	19	myocardial	myocardial	JJ
cord-258708-da6x5rxa	106	20	injury	injury	NN
cord-258708-da6x5rxa	106	21	.	.	.
cord-258708-da6x5rxa	107	1	Moreover	moreover	RB
cord-258708-da6x5rxa	107	2	,	,	,
cord-258708-da6x5rxa	107	3	given	give	VBN
cord-258708-da6x5rxa	107	4	the	the	DT
cord-258708-da6x5rxa	107	5	presence	presence	NN
cord-258708-da6x5rxa	107	6	of	of	IN
cord-258708-da6x5rxa	107	7	abundant	abundant	JJ
cord-258708-da6x5rxa	107	8	distribution	distribution	NN
cord-258708-da6x5rxa	107	9	of	of	IN
cord-258708-da6x5rxa	107	10	ACE2	ACE2	NNP
cord-258708-da6x5rxa	107	11	in	in	IN
cord-258708-da6x5rxa	107	12	cardiomyocytes	cardiomyocyte	NNS
cord-258708-da6x5rxa	107	13	(	(	-LRB-
cord-258708-da6x5rxa	107	14	20	20	CD
cord-258708-da6x5rxa	107	15	)	)	-RRB-
cord-258708-da6x5rxa	107	16	,	,	,
cord-258708-da6x5rxa	107	17	some	some	DT
cord-258708-da6x5rxa	107	18	have	have	VBP
cord-258708-da6x5rxa	107	19	suggested	suggest	VBN
cord-258708-da6x5rxa	107	20	that	that	IN
cord-258708-da6x5rxa	107	21	myocarditis	myocarditis	NN
cord-258708-da6x5rxa	107	22	might	may	MD
cord-258708-da6x5rxa	107	23	elucidate	elucidate	VB
cord-258708-da6x5rxa	107	24	rise	rise	NN
cord-258708-da6x5rxa	107	25	of	of	IN
cord-258708-da6x5rxa	107	26	TnT	TnT	NNP
cord-258708-da6x5rxa	107	27	in	in	IN
cord-258708-da6x5rxa	107	28	some	some	DT
cord-258708-da6x5rxa	107	29	cases	case	NNS
cord-258708-da6x5rxa	107	30	,	,	,
cord-258708-da6x5rxa	107	31	mainly	mainly	RB
cord-258708-da6x5rxa	107	32	as	as	IN
cord-258708-da6x5rxa	107	33	acute	acute	JJ
cord-258708-da6x5rxa	107	34	left	leave	VBN
cord-258708-da6x5rxa	107	35	ventricular	ventricular	JJ
cord-258708-da6x5rxa	107	36	failure	failure	NN
cord-258708-da6x5rxa	107	37	in	in	IN
cord-258708-da6x5rxa	107	38	some	some	DT
cord-258708-da6x5rxa	107	39	cases	case	NNS
cord-258708-da6x5rxa	107	40	(	(	-LRB-
cord-258708-da6x5rxa	107	41	45	45	CD
cord-258708-da6x5rxa	107	42	,	,	,
cord-258708-da6x5rxa	107	43	46	46	CD
cord-258708-da6x5rxa	107	44	)	)	-RRB-
cord-258708-da6x5rxa	107	45	.	.	.
cord-258708-da6x5rxa	108	1	Notably	notably	RB
cord-258708-da6x5rxa	108	2	,	,	,
cord-258708-da6x5rxa	108	3	a	a	DT
cord-258708-da6x5rxa	108	4	rise	rise	NN
cord-258708-da6x5rxa	108	5	of	of	IN
cord-258708-da6x5rxa	108	6	cardiac	cardiac	NN
cord-258708-da6x5rxa	108	7	TnT	tnt	NN
cord-258708-da6x5rxa	108	8	should	should	MD
cord-258708-da6x5rxa	108	9	not	not	RB
cord-258708-da6x5rxa	108	10	be	be	VB
cord-258708-da6x5rxa	108	11	considered	consider	VBN
cord-258708-da6x5rxa	108	12	evidence	evidence	NN
cord-258708-da6x5rxa	108	13	for	for	IN
cord-258708-da6x5rxa	108	14	an	an	DT
cord-258708-da6x5rxa	108	15	acute	acute	JJ
cord-258708-da6x5rxa	108	16	MI	mi	NN
cord-258708-da6x5rxa	108	17	(	(	-LRB-
cord-258708-da6x5rxa	108	18	47	47	CD
cord-258708-da6x5rxa	108	19	)	)	-RRB-
cord-258708-da6x5rxa	108	20	.	.	.
cord-258708-da6x5rxa	109	1	This	this	DT
cord-258708-da6x5rxa	109	2	should	should	MD
cord-258708-da6x5rxa	109	3	be	be	VB
cord-258708-da6x5rxa	109	4	based	base	VBN
cord-258708-da6x5rxa	109	5	on	on	IN
cord-258708-da6x5rxa	109	6	clinical	clinical	JJ
cord-258708-da6x5rxa	109	7	assessment	assessment	NN
cord-258708-da6x5rxa	109	8	,	,	,
cord-258708-da6x5rxa	109	9	and	and	CC
cord-258708-da6x5rxa	109	10	ECG	ECG	NNP
cord-258708-da6x5rxa	109	11	,	,	,
cord-258708-da6x5rxa	109	12	where	where	WRB
cord-258708-da6x5rxa	109	13	cardiac	cardiac	JJ
cord-258708-da6x5rxa	109	14	troponin	troponin	JJ
cord-258708-da6x5rxa	109	15	elevations	elevation	NNS
cord-258708-da6x5rxa	109	16	of	of	IN
cord-258708-da6x5rxa	109	17	cardiac	cardiac	NN
cord-258708-da6x5rxa	109	18	TnT	TnT	NNP
cord-258708-da6x5rxa	109	19	can	can	MD
cord-258708-da6x5rxa	109	20	inform	inform	VB
cord-258708-da6x5rxa	109	21	the	the	DT
cord-258708-da6x5rxa	109	22	diagnosis	diagnosis	NN
cord-258708-da6x5rxa	109	23	of	of	IN
cord-258708-da6x5rxa	109	24	a	a	DT
cord-258708-da6x5rxa	109	25	number	number	NN
cord-258708-da6x5rxa	109	26	of	of	IN
cord-258708-da6x5rxa	109	27	cardiac	cardiac	JJ
cord-258708-da6x5rxa	109	28	conditions	condition	NNS
cord-258708-da6x5rxa	109	29	related	relate	VBN
cord-258708-da6x5rxa	109	30	to	to	IN
cord-258708-da6x5rxa	109	31	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	109	32	(	(	-LRB-
cord-258708-da6x5rxa	109	33	46	46	CD
cord-258708-da6x5rxa	109	34	)	)	-RRB-
cord-258708-da6x5rxa	109	35	.	.	.
cord-258708-da6x5rxa	110	1	Elevated	elevated	JJ
cord-258708-da6x5rxa	110	2	TnT	TnT	NNP
cord-258708-da6x5rxa	110	3	is	be	VBZ
cord-258708-da6x5rxa	110	4	likely	likely	JJ
cord-258708-da6x5rxa	110	5	to	to	TO
cord-258708-da6x5rxa	110	6	be	be	VB
cord-258708-da6x5rxa	110	7	multifactorial	multifactorial	JJ
cord-258708-da6x5rxa	110	8	,	,	,
cord-258708-da6x5rxa	110	9	and	and	CC
cord-258708-da6x5rxa	110	10	less	less	RBR
cord-258708-da6x5rxa	110	11	likely	likely	JJ
cord-258708-da6x5rxa	110	12	to	to	TO
cord-258708-da6x5rxa	110	13	be	be	VB
cord-258708-da6x5rxa	110	14	attributable	attributable	JJ
cord-258708-da6x5rxa	110	15	to	to	IN
cord-258708-da6x5rxa	110	16	atherothrombotic	atherothrombotic	JJ
cord-258708-da6x5rxa	110	17	coronary	coronary	JJ
cord-258708-da6x5rxa	110	18	occlusion	occlusion	NN
cord-258708-da6x5rxa	110	19	(	(	-LRB-
cord-258708-da6x5rxa	110	20	47	47	CD
cord-258708-da6x5rxa	110	21	)	)	-RRB-
cord-258708-da6x5rxa	110	22	.	.	.
cord-258708-da6x5rxa	111	1	Indeed	indeed	RB
cord-258708-da6x5rxa	111	2	,	,	,
cord-258708-da6x5rxa	111	3	16	16	CD
cord-258708-da6x5rxa	111	4	%	%	NN
cord-258708-da6x5rxa	111	5	of	of	IN
cord-258708-da6x5rxa	111	6	patients	patient	NNS
cord-258708-da6x5rxa	111	7	with	with	IN
cord-258708-da6x5rxa	111	8	underlying	underlie	VBG
cord-258708-da6x5rxa	111	9	CVD	CVD	NNP
cord-258708-da6x5rxa	111	10	but	but	CC
cord-258708-da6x5rxa	111	11	with	with	IN
cord-258708-da6x5rxa	111	12	normal	normal	JJ
cord-258708-da6x5rxa	111	13	TnT	TnT	NNP
cord-258708-da6x5rxa	111	14	levels	level	NNS
cord-258708-da6x5rxa	111	15	had	have	VBD
cord-258708-da6x5rxa	111	16	a	a	DT
cord-258708-da6x5rxa	111	17	relatively	relatively	RB
cord-258708-da6x5rxa	111	18	favorable	favorable	JJ
cord-258708-da6x5rxa	111	19	outcome	outcome	NN
cord-258708-da6x5rxa	111	20	(	(	-LRB-
cord-258708-da6x5rxa	111	21	43	43	CD
cord-258708-da6x5rxa	111	22	)	)	-RRB-
cord-258708-da6x5rxa	111	23	.	.	.
cord-258708-da6x5rxa	112	1	Available	available	JJ
cord-258708-da6x5rxa	112	2	data	datum	NNS
cord-258708-da6x5rxa	112	3	on	on	IN
cord-258708-da6x5rxa	112	4	the	the	DT
cord-258708-da6x5rxa	112	5	role	role	NN
cord-258708-da6x5rxa	112	6	of	of	IN
cord-258708-da6x5rxa	112	7	cardiac	cardiac	JJ
cord-258708-da6x5rxa	112	8	biomarkers	biomarker	NNS
cord-258708-da6x5rxa	112	9	,	,	,
cord-258708-da6x5rxa	112	10	supported	support	VBD
cord-258708-da6x5rxa	112	11	the	the	DT
cord-258708-da6x5rxa	112	12	role	role	NN
cord-258708-da6x5rxa	112	13	of	of	IN
cord-258708-da6x5rxa	112	14	assessing	assess	VBG
cord-258708-da6x5rxa	112	15	TnT	TnT	NNP
cord-258708-da6x5rxa	112	16	and	and	CC
cord-258708-da6x5rxa	112	17	natriuretic	natriuretic	JJ
cord-258708-da6x5rxa	112	18	peptides	peptide	NNS
cord-258708-da6x5rxa	112	19	(	(	-LRB-
cord-258708-da6x5rxa	112	20	NT	NT	NNP
cord-258708-da6x5rxa	112	21	-	-	HYPH
cord-258708-da6x5rxa	112	22	proBNP	proBNP	NNP
cord-258708-da6x5rxa	112	23	and	and	CC
cord-258708-da6x5rxa	112	24	BNP	BNP	NNP
cord-258708-da6x5rxa	112	25	)	)	-RRB-
cord-258708-da6x5rxa	112	26	for	for	IN
cord-258708-da6x5rxa	112	27	cardiac	cardiac	JJ
cord-258708-da6x5rxa	112	28	risk	risk	NN
cord-258708-da6x5rxa	112	29	stratification	stratification	NN
cord-258708-da6x5rxa	112	30	and	and	CC
cord-258708-da6x5rxa	112	31	prognostication	prognostication	NN
cord-258708-da6x5rxa	112	32	of	of	IN
cord-258708-da6x5rxa	112	33	patients	patient	NNS
cord-258708-da6x5rxa	112	34	with	with	IN
cord-258708-da6x5rxa	112	35	severe	severe	JJ
cord-258708-da6x5rxa	112	36	COVID-19	covid-19	NN
cord-258708-da6x5rxa	112	37	(	(	-LRB-
cord-258708-da6x5rxa	112	38	48	48	CD
cord-258708-da6x5rxa	112	39	)	)	-RRB-
cord-258708-da6x5rxa	112	40	,	,	.
cord-258708-da6x5rxa	113	1	Based	base	VBN
cord-258708-da6x5rxa	113	2	on	on	IN
cord-258708-da6x5rxa	113	3	the	the	DT
cord-258708-da6x5rxa	113	4	evidence	evidence	NN
cord-258708-da6x5rxa	113	5	of	of	IN
cord-258708-da6x5rxa	113	6	myocardial	myocardial	JJ
cord-258708-da6x5rxa	113	7	injury	injury	NN
cord-258708-da6x5rxa	113	8	and	and	CC
cord-258708-da6x5rxa	113	9	the	the	DT
cord-258708-da6x5rxa	113	10	presence	presence	NN
cord-258708-da6x5rxa	113	11	of	of	IN
cord-258708-da6x5rxa	113	12	CV	CV	NNP
cord-258708-da6x5rxa	113	13	complications	complication	NNS
cord-258708-da6x5rxa	113	14	,	,	,
cord-258708-da6x5rxa	113	15	this	this	DT
cord-258708-da6x5rxa	113	16	might	may	MD
cord-258708-da6x5rxa	113	17	improve	improve	VB
cord-258708-da6x5rxa	113	18	CV	CV	NNP
cord-258708-da6x5rxa	113	19	care	care	NN
cord-258708-da6x5rxa	113	20	among	among	IN
cord-258708-da6x5rxa	113	21	COVID-19	covid-19	JJ
cord-258708-da6x5rxa	113	22	patients	patient	NNS
cord-258708-da6x5rxa	113	23	,	,	,
cord-258708-da6x5rxa	113	24	as	as	RB
cord-258708-da6x5rxa	113	25	well	well	RB
cord-258708-da6x5rxa	113	26	as	as	IN
cord-258708-da6x5rxa	113	27	decrease	decrease	VB
cord-258708-da6x5rxa	113	28	the	the	DT
cord-258708-da6x5rxa	113	29	risk	risk	NN
cord-258708-da6x5rxa	113	30	of	of	IN
cord-258708-da6x5rxa	113	31	infection	infection	NN
cord-258708-da6x5rxa	113	32	,	,	,
cord-258708-da6x5rxa	113	33	but	but	CC
cord-258708-da6x5rxa	113	34	there	there	EX
cord-258708-da6x5rxa	113	35	could	could	MD
cord-258708-da6x5rxa	113	36	be	be	VB
cord-258708-da6x5rxa	113	37	some	some	DT
cord-258708-da6x5rxa	113	38	limitations	limitation	NNS
cord-258708-da6x5rxa	113	39	(	(	-LRB-
cord-258708-da6x5rxa	113	40	49	49	CD
cord-258708-da6x5rxa	113	41	)	)	-RRB-
cord-258708-da6x5rxa	113	42	.	.	.
cord-258708-da6x5rxa	114	1	Nevertheless	nevertheless	RB
cord-258708-da6x5rxa	114	2	,	,	,
cord-258708-da6x5rxa	114	3	additional	additional	JJ
cord-258708-da6x5rxa	114	4	novel	novel	JJ
cord-258708-da6x5rxa	114	5	biomarkers	biomarker	NNS
cord-258708-da6x5rxa	114	6	are	be	VBP
cord-258708-da6x5rxa	114	7	needed	need	VBN
cord-258708-da6x5rxa	114	8	for	for	IN
cord-258708-da6x5rxa	114	9	CV	cv	NN
cord-258708-da6x5rxa	114	10	disease	disease	NN
cord-258708-da6x5rxa	114	11	diagnosis	diagnosis	NN
cord-258708-da6x5rxa	114	12	,	,	,
cord-258708-da6x5rxa	114	13	risk	risk	NN
cord-258708-da6x5rxa	114	14	stratification	stratification	NN
cord-258708-da6x5rxa	114	15	,	,	,
cord-258708-da6x5rxa	114	16	and	and	CC
cord-258708-da6x5rxa	114	17	management	management	NN
cord-258708-da6x5rxa	114	18	in	in	IN
cord-258708-da6x5rxa	114	19	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	114	20	Rise	Rise	NNP
cord-258708-da6x5rxa	114	21	in	in	IN
cord-258708-da6x5rxa	114	22	inflammation	inflammation	NN
cord-258708-da6x5rxa	114	23	in	in	IN
cord-258708-da6x5rxa	114	24	the	the	DT
cord-258708-da6x5rxa	114	25	myocardium	myocardium	NN
cord-258708-da6x5rxa	114	26	can	can	MD
cord-258708-da6x5rxa	114	27	result	result	VB
cord-258708-da6x5rxa	114	28	in	in	IN
cord-258708-da6x5rxa	114	29	CV	cv	NN
cord-258708-da6x5rxa	114	30	complications	complication	NNS
cord-258708-da6x5rxa	114	31	,	,	,
cord-258708-da6x5rxa	114	32	such	such	JJ
cord-258708-da6x5rxa	114	33	as	as	IN
cord-258708-da6x5rxa	114	34	myocarditis	myocarditis	NN
cord-258708-da6x5rxa	114	35	,	,	,
cord-258708-da6x5rxa	114	36	heart	heart	NN
cord-258708-da6x5rxa	114	37	failure	failure	NN
cord-258708-da6x5rxa	114	38	,	,	,
cord-258708-da6x5rxa	114	39	cardiac	cardiac	NN
cord-258708-da6x5rxa	114	40	arrhythmias	arrhythmia	NNS
cord-258708-da6x5rxa	114	41	,	,	,
cord-258708-da6x5rxa	114	42	and	and	CC
cord-258708-da6x5rxa	114	43	acute	acute	JJ
cord-258708-da6x5rxa	114	44	coronary	coronary	JJ
cord-258708-da6x5rxa	114	45	syndrome	syndrome	NN
cord-258708-da6x5rxa	114	46	(	(	-LRB-
cord-258708-da6x5rxa	114	47	ACS	ACS	NNP
cord-258708-da6x5rxa	114	48	)	)	-RRB-
cord-258708-da6x5rxa	115	1	(	(	-LRB-
cord-258708-da6x5rxa	115	2	Figure	figure	NN
cord-258708-da6x5rxa	115	3	2	2	CD
cord-258708-da6x5rxa	115	4	)	)	-RRB-
cord-258708-da6x5rxa	115	5	(	(	-LRB-
cord-258708-da6x5rxa	115	6	50	50	CD
cord-258708-da6x5rxa	115	7	)	)	-RRB-
cord-258708-da6x5rxa	115	8	.	.	.
cord-258708-da6x5rxa	116	1	However	however	RB
cord-258708-da6x5rxa	116	2	,	,	,
cord-258708-da6x5rxa	116	3	elevated	elevated	JJ
cord-258708-da6x5rxa	116	4	high	high	JJ
cord-258708-da6x5rxa	116	5	sensitivity	sensitivity	NN
cord-258708-da6x5rxa	116	6	TnT	tnt	NN
cord-258708-da6x5rxa	116	7	with	with	IN
cord-258708-da6x5rxa	116	8	other	other	JJ
cord-258708-da6x5rxa	116	9	inflammatory	inflammatory	JJ
cord-258708-da6x5rxa	116	10	vascular	vascular	JJ
cord-258708-da6x5rxa	116	11	biomarkers	biomarker	NNS
cord-258708-da6x5rxa	116	12	(	(	-LRB-
cord-258708-da6x5rxa	116	13	d	d	NN
cord-258708-da6x5rxa	116	14	-	-	HYPH
cord-258708-da6x5rxa	116	15	dimer	dimer	JJ
cord-258708-da6x5rxa	116	16	,	,	,
cord-258708-da6x5rxa	116	17	ferritin	ferritin	NN
cord-258708-da6x5rxa	116	18	,	,	,
cord-258708-da6x5rxa	116	19	IL-6	IL-6	NNP
cord-258708-da6x5rxa	116	20	,	,	,
cord-258708-da6x5rxa	116	21	and	and	CC
cord-258708-da6x5rxa	116	22	lactate	lactate	NN
cord-258708-da6x5rxa	116	23	dehydrogenase	dehydrogenase	NN
cord-258708-da6x5rxa	116	24	)	)	-RRB-
cord-258708-da6x5rxa	116	25	may	may	MD
cord-258708-da6x5rxa	116	26	rise	rise	VB
cord-258708-da6x5rxa	116	27	the	the	DT
cord-258708-da6x5rxa	116	28	possibility	possibility	NN
cord-258708-da6x5rxa	116	29	that	that	IN
cord-258708-da6x5rxa	116	30	these	these	DT
cord-258708-da6x5rxa	116	31	changes	change	NNS
cord-258708-da6x5rxa	116	32	are	be	VBP
cord-258708-da6x5rxa	116	33	specific	specific	JJ
cord-258708-da6x5rxa	116	34	effects	effect	NNS
cord-258708-da6x5rxa	116	35	of	of	IN
cord-258708-da6x5rxa	116	36	the	the	DT
cord-258708-da6x5rxa	116	37	virus	virus	NN
cord-258708-da6x5rxa	116	38	,	,	,
cord-258708-da6x5rxa	116	39	reflects	reflect	VBZ
cord-258708-da6x5rxa	116	40	a	a	DT
cord-258708-da6x5rxa	116	41	cytokine	cytokine	NN
cord-258708-da6x5rxa	116	42	storm	storm	NN
cord-258708-da6x5rxa	116	43	,	,	,
cord-258708-da6x5rxa	116	44	or	or	CC
cord-258708-da6x5rxa	116	45	is	be	VBZ
cord-258708-da6x5rxa	116	46	merely	merely	RB
cord-258708-da6x5rxa	116	47	an	an	DT
cord-258708-da6x5rxa	116	48	isolated	isolated	JJ
cord-258708-da6x5rxa	116	49	myocardial	myocardial	JJ
cord-258708-da6x5rxa	116	50	injury	injury	NN
cord-258708-da6x5rxa	116	51	(	(	-LRB-
cord-258708-da6x5rxa	116	52	Table	Table	NNP
cord-258708-da6x5rxa	116	53	2	2	CD
cord-258708-da6x5rxa	116	54	)	)	-RRB-
cord-258708-da6x5rxa	116	55	.	.	.
cord-258708-da6x5rxa	117	1	As	as	IN
cord-258708-da6x5rxa	117	2	an	an	DT
cord-258708-da6x5rxa	117	3	example	example	NN
cord-258708-da6x5rxa	117	4	of	of	IN
cord-258708-da6x5rxa	117	5	this	this	DT
cord-258708-da6x5rxa	117	6	statement	statement	NN
cord-258708-da6x5rxa	117	7	,	,	,
cord-258708-da6x5rxa	117	8	one	one	CD
cord-258708-da6x5rxa	117	9	case	case	NN
cord-258708-da6x5rxa	117	10	reported	report	VBD
cord-258708-da6x5rxa	117	11	a	a	DT
cord-258708-da6x5rxa	117	12	man	man	NN
cord-258708-da6x5rxa	117	13	presenting	present	VBG
cord-258708-da6x5rxa	117	14	with	with	IN
cord-258708-da6x5rxa	117	15	chest	chest	NN
cord-258708-da6x5rxa	117	16	pain	pain	NN
cord-258708-da6x5rxa	117	17	,	,	,
cord-258708-da6x5rxa	117	18	and	and	CC
cord-258708-da6x5rxa	117	19	ST	ST	NNP
cord-258708-da6x5rxa	117	20	-	-	HYPH
cord-258708-da6x5rxa	117	21	segment	segment	NN
cord-258708-da6x5rxa	117	22	elevation	elevation	NN
cord-258708-da6x5rxa	117	23	without	without	IN
cord-258708-da6x5rxa	117	24	coronary	coronary	JJ
cord-258708-da6x5rxa	117	25	obstruction	obstruction	NN
cord-258708-da6x5rxa	117	26	as	as	RB
cord-258708-da6x5rxa	117	27	well	well	RB
cord-258708-da6x5rxa	117	28	as	as	IN
cord-258708-da6x5rxa	117	29	elevated	elevated	JJ
cord-258708-da6x5rxa	117	30	cardiac	cardiac	JJ
cord-258708-da6x5rxa	117	31	biomarkers	biomarker	NNS
cord-258708-da6x5rxa	117	32	(	(	-LRB-
cord-258708-da6x5rxa	117	33	TnT	TnT	NNP
cord-258708-da6x5rxa	117	34	serum	serum	NN
cord-258708-da6x5rxa	117	35	levels	level	NNS
cord-258708-da6x5rxa	118	1	>	>	XX
cord-258708-da6x5rxa	119	1	10	10	CD
cord-258708-da6x5rxa	119	2	ng	ng	NN
cord-258708-da6x5rxa	119	3	/	/	SYM
cord-258708-da6x5rxa	119	4	mL	mL	NNP
cord-258708-da6x5rxa	119	5	,	,	,
cord-258708-da6x5rxa	119	6	NT	NT	NNP
cord-258708-da6x5rxa	119	7	-	-	HYPH
cord-258708-da6x5rxa	119	8	proBNP>21,000	proBNP>21,000	NNP
cord-258708-da6x5rxa	119	9	pg	pg	NN
cord-258708-da6x5rxa	119	10	/	/	SYM
cord-258708-da6x5rxa	119	11	mL	ml	NN
cord-258708-da6x5rxa	119	12	)	)	-RRB-
cord-258708-da6x5rxa	119	13	(	(	-LRB-
cord-258708-da6x5rxa	119	14	41	41	CD
cord-258708-da6x5rxa	119	15	)	)	-RRB-
cord-258708-da6x5rxa	119	16	.	.	.
cord-258708-da6x5rxa	120	1	Another	another	DT
cord-258708-da6x5rxa	120	2	study	study	NN
cord-258708-da6x5rxa	120	3	found	find	VBD
cord-258708-da6x5rxa	120	4	IL-6	IL-6	NNP
cord-258708-da6x5rxa	120	5	over	over	IN
cord-258708-da6x5rxa	120	6	4.3	4.3	CD
cord-258708-da6x5rxa	120	7	pg	pg	NNS
cord-258708-da6x5rxa	120	8	/	/	SYM
cord-258708-da6x5rxa	120	9	mL	mL	NNP
cord-258708-da6x5rxa	120	10	,	,	,
cord-258708-da6x5rxa	120	11	and	and	CC
cord-258708-da6x5rxa	120	12	ddimer	ddimer	NNP
cord-258708-da6x5rxa	120	13	(	(	-LRB-
cord-258708-da6x5rxa	120	14	a	a	DT
cord-258708-da6x5rxa	120	15	fibrin	fibrin	NN
cord-258708-da6x5rxa	120	16	degradation	degradation	NN
cord-258708-da6x5rxa	120	17	product	product	NN
cord-258708-da6x5rxa	120	18	)	)	-RRB-
cord-258708-da6x5rxa	120	19	over	over	IN
cord-258708-da6x5rxa	120	20	0.28	0.28	CD
cord-258708-da6x5rxa	120	21	µg	µg	NNP
cord-258708-da6x5rxa	120	22	/	/	SYM
cord-258708-da6x5rxa	120	23	L	L	NNP
cord-258708-da6x5rxa	120	24	,	,	,
cord-258708-da6x5rxa	120	25	and	and	CC
cord-258708-da6x5rxa	120	26	had	have	VBD
cord-258708-da6x5rxa	120	27	a	a	DT
cord-258708-da6x5rxa	120	28	possible	possible	JJ
cord-258708-da6x5rxa	120	29	predictive	predictive	JJ
cord-258708-da6x5rxa	120	30	value	value	NN
cord-258708-da6x5rxa	120	31	for	for	IN
cord-258708-da6x5rxa	120	32	the	the	DT
cord-258708-da6x5rxa	120	33	severity	severity	NN
cord-258708-da6x5rxa	120	34	of	of	IN
cord-258708-da6x5rxa	120	35	SARS	SARS	NNP
cord-258708-da6x5rxa	120	36	-	-	HYPH
cord-258708-da6x5rxa	120	37	COV-2	COV-2	NNP
cord-258708-da6x5rxa	120	38	infection	infection	NN
cord-258708-da6x5rxa	120	39	(	(	-LRB-
cord-258708-da6x5rxa	120	40	51	51	CD
cord-258708-da6x5rxa	120	41	)	)	-RRB-
cord-258708-da6x5rxa	120	42	.	.	.
cord-258708-da6x5rxa	121	1	The	the	DT
cord-258708-da6x5rxa	121	2	finding	finding	NN
cord-258708-da6x5rxa	121	3	of	of	IN
cord-258708-da6x5rxa	121	4	increased	increase	VBN
cord-258708-da6x5rxa	121	5	d	d	NN
cord-258708-da6x5rxa	121	6	-	-	HYPH
cord-258708-da6x5rxa	121	7	dimer	dimer	JJ
cord-258708-da6x5rxa	121	8	levels	level	NNS
cord-258708-da6x5rxa	121	9	in	in	IN
cord-258708-da6x5rxa	121	10	patients	patient	NNS
cord-258708-da6x5rxa	121	11	with	with	IN
cord-258708-da6x5rxa	121	12	severe	severe	JJ
cord-258708-da6x5rxa	121	13	COVID-19	covid-19	NN
cord-258708-da6x5rxa	121	14	has	have	VBZ
cord-258708-da6x5rxa	121	15	prompted	prompt	VBN
cord-258708-da6x5rxa	121	16	questions	question	NNS
cord-258708-da6x5rxa	121	17	regarding	regard	VBG
cord-258708-da6x5rxa	121	18	the	the	DT
cord-258708-da6x5rxa	121	19	existence	existence	NN
cord-258708-da6x5rxa	121	20	of	of	IN
cord-258708-da6x5rxa	121	21	disseminated	disseminate	VBN
cord-258708-da6x5rxa	121	22	intravascular	intravascular	JJ
cord-258708-da6x5rxa	121	23	coagulation	coagulation	NN
cord-258708-da6x5rxa	121	24	which	which	WDT
cord-258708-da6x5rxa	121	25	may	may	MD
cord-258708-da6x5rxa	121	26	predispose	predispose	VB
cord-258708-da6x5rxa	121	27	patients	patient	NNS
cord-258708-da6x5rxa	121	28	to	to	TO
cord-258708-da6x5rxa	121	29	thrombosis	thrombosis	NN
cord-258708-da6x5rxa	121	30	risk	risk	NN
cord-258708-da6x5rxa	121	31	(	(	-LRB-
cord-258708-da6x5rxa	121	32	4	4	CD
cord-258708-da6x5rxa	121	33	)	)	-RRB-
cord-258708-da6x5rxa	121	34	.	.	.
cord-258708-da6x5rxa	122	1	These	these	DT
cord-258708-da6x5rxa	122	2	abnormalities	abnormality	NNS
cord-258708-da6x5rxa	122	3	may	may	MD
cord-258708-da6x5rxa	122	4	then	then	RB
cord-258708-da6x5rxa	122	5	lead	lead	VB
cord-258708-da6x5rxa	122	6	to	to	IN
cord-258708-da6x5rxa	122	7	ACS	ACS	NNP
cord-258708-da6x5rxa	122	8	(	(	-LRB-
cord-258708-da6x5rxa	122	9	52	52	CD
cord-258708-da6x5rxa	122	10	)	)	-RRB-
cord-258708-da6x5rxa	122	11	.	.	.
cord-258708-da6x5rxa	123	1	Patients	patient	NNS
cord-258708-da6x5rxa	123	2	with	with	IN
cord-258708-da6x5rxa	123	3	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	123	4	are	be	VBP
cord-258708-da6x5rxa	123	5	also	also	RB
cord-258708-da6x5rxa	123	6	at	at	IN
cord-258708-da6x5rxa	123	7	an	an	DT
cord-258708-da6x5rxa	123	8	increased	increase	VBN
cord-258708-da6x5rxa	123	9	risk	risk	NN
cord-258708-da6x5rxa	123	10	of	of	IN
cord-258708-da6x5rxa	123	11	venous	venous	JJ
cord-258708-da6x5rxa	123	12	thromboembolic	thromboembolic	JJ
cord-258708-da6x5rxa	123	13	event	event	NN
cord-258708-da6x5rxa	123	14	(	(	-LRB-
cord-258708-da6x5rxa	123	15	Figure	figure	NN
cord-258708-da6x5rxa	123	16	2	2	CD
cord-258708-da6x5rxa	123	17	)	)	-RRB-
cord-258708-da6x5rxa	123	18	.	.	.
cord-258708-da6x5rxa	124	1	The	the	DT
cord-258708-da6x5rxa	124	2	most	most	RBS
cord-258708-da6x5rxa	124	3	consistent	consistent	JJ
cord-258708-da6x5rxa	124	4	hemostatic	hemostatic	JJ
cord-258708-da6x5rxa	124	5	abnormalities	abnormality	NNS
cord-258708-da6x5rxa	124	6	with	with	IN
cord-258708-da6x5rxa	124	7	COVID-19	COVID-19	,
cord-258708-da6x5rxa	124	8	include	include	VBP
cord-258708-da6x5rxa	124	9	mild	mild	JJ
cord-258708-da6x5rxa	124	10	thrombocytopenia	thrombocytopenia	NN
cord-258708-da6x5rxa	124	11	,	,	,
cord-258708-da6x5rxa	124	12	and	and	CC
cord-258708-da6x5rxa	124	13	increased	increase	VBN
cord-258708-da6x5rxa	124	14	d	d	NN
cord-258708-da6x5rxa	124	15	-	-	HYPH
cord-258708-da6x5rxa	124	16	dimer	dimer	JJ
cord-258708-da6x5rxa	124	17	levels	level	NNS
cord-258708-da6x5rxa	124	18	(	(	-LRB-
cord-258708-da6x5rxa	124	19	53	53	CD
cord-258708-da6x5rxa	124	20	)	)	-RRB-
cord-258708-da6x5rxa	124	21	.	.	.
cord-258708-da6x5rxa	125	1	Thus	thus	RB
cord-258708-da6x5rxa	125	2	,	,	,
cord-258708-da6x5rxa	125	3	demonstrating	demonstrate	VBG
cord-258708-da6x5rxa	125	4	a	a	DT
cord-258708-da6x5rxa	125	5	promise	promise	NN
cord-258708-da6x5rxa	125	6	to	to	TO
cord-258708-da6x5rxa	125	7	hold	hold	VB
cord-258708-da6x5rxa	125	8	prognostic	prognostic	JJ
cord-258708-da6x5rxa	125	9	value	value	NN
cord-258708-da6x5rxa	125	10	of	of	IN
cord-258708-da6x5rxa	125	11	d	d	NN
cord-258708-da6x5rxa	125	12	-	-	:
cord-258708-da6x5rxa	125	13	dimers	dimer	NNS
cord-258708-da6x5rxa	125	14	in	in	IN
cord-258708-da6x5rxa	125	15	COVID-19	covid-19	CD
cord-258708-da6x5rxa	125	16	patients	patient	NNS
cord-258708-da6x5rxa	125	17	(	(	-LRB-
cord-258708-da6x5rxa	125	18	54	54	CD
cord-258708-da6x5rxa	125	19	)	)	-RRB-
cord-258708-da6x5rxa	125	20	.	.	.
cord-258708-da6x5rxa	126	1	However	however	RB
cord-258708-da6x5rxa	126	2	,	,	,
cord-258708-da6x5rxa	126	3	the	the	DT
cord-258708-da6x5rxa	126	4	reason	reason	NN
cord-258708-da6x5rxa	126	5	behind	behind	IN
cord-258708-da6x5rxa	126	6	elevated	elevated	JJ
cord-258708-da6x5rxa	126	7	ddimer	ddimer	NN
cord-258708-da6x5rxa	126	8	levels	level	NNS
cord-258708-da6x5rxa	126	9	whether	whether	IN
cord-258708-da6x5rxa	126	10	is	be	VBZ
cord-258708-da6x5rxa	126	11	thrombosis	thrombosis	NN
cord-258708-da6x5rxa	126	12	/	/	SYM
cord-258708-da6x5rxa	126	13	hypercoagulability	hypercoagulability	NN
cord-258708-da6x5rxa	126	14	or	or	CC
cord-258708-da6x5rxa	126	15	proinflammatory	proinflammatory	JJ
cord-258708-da6x5rxa	126	16	response	response	NN
cord-258708-da6x5rxa	126	17	remains	remain	VBZ
cord-258708-da6x5rxa	126	18	unclear	unclear	JJ
cord-258708-da6x5rxa	126	19	until	until	IN
cord-258708-da6x5rxa	126	20	now	now	RB
cord-258708-da6x5rxa	126	21	.	.	.
cord-258708-da6x5rxa	127	1	More	more	RBR
cord-258708-da6x5rxa	127	2	recently	recently	RB
cord-258708-da6x5rxa	127	3	,	,	,
cord-258708-da6x5rxa	127	4	inflammatory	inflammatory	JJ
cord-258708-da6x5rxa	127	5	response	response	NN
cord-258708-da6x5rxa	127	6	,	,	,
cord-258708-da6x5rxa	127	7	hypoxic	hypoxic	JJ
cord-258708-da6x5rxa	127	8	abnormalities	abnormality	NNS
cord-258708-da6x5rxa	127	9	,	,	,
cord-258708-da6x5rxa	127	10	and	and	CC
cord-258708-da6x5rxa	127	11	electrolytic	electrolytic	JJ
cord-258708-da6x5rxa	127	12	disturbance	disturbance	NN
cord-258708-da6x5rxa	127	13	are	be	VBP
cord-258708-da6x5rxa	127	14	found	find	VBN
cord-258708-da6x5rxa	127	15	to	to	TO
cord-258708-da6x5rxa	127	16	be	be	VB
cord-258708-da6x5rxa	127	17	one	one	CD
cord-258708-da6x5rxa	127	18	of	of	IN
cord-258708-da6x5rxa	127	19	the	the	DT
cord-258708-da6x5rxa	127	20	physiologic	physiologic	JJ
cord-258708-da6x5rxa	127	21	sequelae	sequela	NNS
cord-258708-da6x5rxa	127	22	of	of	IN
cord-258708-da6x5rxa	127	23	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	127	24	leading	lead	VBG
cord-258708-da6x5rxa	127	25	to	to	IN
cord-258708-da6x5rxa	127	26	arrhythmic	arrhythmic	JJ
cord-258708-da6x5rxa	127	27	risk	risk	NN
cord-258708-da6x5rxa	127	28	.	.	.
cord-258708-da6x5rxa	128	1	Notably	notably	RB
cord-258708-da6x5rxa	128	2	,	,	,
cord-258708-da6x5rxa	128	3	heart	heart	NN
cord-258708-da6x5rxa	128	4	palpitation	palpitation	NN
cord-258708-da6x5rxa	128	5	was	be	VBD
cord-258708-da6x5rxa	128	6	reported	report	VBN
cord-258708-da6x5rxa	128	7	as	as	IN
cord-258708-da6x5rxa	128	8	one	one	CD
cord-258708-da6x5rxa	128	9	of	of	IN
cord-258708-da6x5rxa	128	10	the	the	DT
cord-258708-da6x5rxa	128	11	most	most	RBS
cord-258708-da6x5rxa	128	12	common	common	JJ
cord-258708-da6x5rxa	128	13	initial	initial	JJ
cord-258708-da6x5rxa	128	14	symptoms	symptom	NNS
cord-258708-da6x5rxa	128	15	in	in	IN
cord-258708-da6x5rxa	128	16	137	137	CD
cord-258708-da6x5rxa	128	17	patients	patient	NNS
cord-258708-da6x5rxa	128	18	presenting	present	VBG
cord-258708-da6x5rxa	128	19	with	with	IN
cord-258708-da6x5rxa	128	20	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	128	21	(	(	-LRB-
cord-258708-da6x5rxa	128	22	7.3	7.3	CD
cord-258708-da6x5rxa	128	23	%	%	NN
cord-258708-da6x5rxa	128	24	)	)	-RRB-
cord-258708-da6x5rxa	128	25	(	(	-LRB-
cord-258708-da6x5rxa	128	26	42	42	CD
cord-258708-da6x5rxa	128	27	)	)	-RRB-
cord-258708-da6x5rxa	128	28	.	.	.
cord-258708-da6x5rxa	129	1	In	in	IN
cord-258708-da6x5rxa	129	2	addition	addition	NN
cord-258708-da6x5rxa	129	3	,	,	,
cord-258708-da6x5rxa	129	4	the	the	DT
cord-258708-da6x5rxa	129	5	elevation	elevation	NN
cord-258708-da6x5rxa	129	6	of	of	IN
cord-258708-da6x5rxa	129	7	serum	serum	NN
cord-258708-da6x5rxa	129	8	Ang	Ang	NNP
cord-258708-da6x5rxa	129	9	exhibits	exhibit	VBZ
cord-258708-da6x5rxa	129	10	a	a	DT
cord-258708-da6x5rxa	129	11	direct	direct	JJ
cord-258708-da6x5rxa	129	12	correlation	correlation	NN
cord-258708-da6x5rxa	129	13	to	to	IN
cord-258708-da6x5rxa	129	14	the	the	DT
cord-258708-da6x5rxa	129	15	viral	viral	JJ
cord-258708-da6x5rxa	129	16	load	load	NN
cord-258708-da6x5rxa	129	17	,	,	,
cord-258708-da6x5rxa	129	18	and	and	CC
cord-258708-da6x5rxa	129	19	lung	lung	NN
cord-258708-da6x5rxa	129	20	injury	injury	NN
cord-258708-da6x5rxa	129	21	(	(	-LRB-
cord-258708-da6x5rxa	129	22	55	55	CD
cord-258708-da6x5rxa	129	23	)	)	-RRB-
cord-258708-da6x5rxa	129	24	.	.	.
cord-258708-da6x5rxa	130	1	At	at	IN
cord-258708-da6x5rxa	130	2	this	this	DT
cord-258708-da6x5rxa	130	3	point	point	NN
cord-258708-da6x5rxa	130	4	,	,	,
cord-258708-da6x5rxa	130	5	plasma	plasma	NN
cord-258708-da6x5rxa	130	6	levels	level	NNS
cord-258708-da6x5rxa	130	7	of	of	IN
cord-258708-da6x5rxa	130	8	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	130	9	II	II	NNP
cord-258708-da6x5rxa	130	10	may	may	MD
cord-258708-da6x5rxa	130	11	offer	offer	VB
cord-258708-da6x5rxa	130	12	a	a	DT
cord-258708-da6x5rxa	130	13	novel	novel	JJ
cord-258708-da6x5rxa	130	14	method	method	NN
cord-258708-da6x5rxa	130	15	of	of	IN
cord-258708-da6x5rxa	130	16	predicting	predict	VBG
cord-258708-da6x5rxa	130	17	disease	disease	NN
cord-258708-da6x5rxa	130	18	severity	severity	NN
cord-258708-da6x5rxa	130	19	(	(	-LRB-
cord-258708-da6x5rxa	130	20	54	54	CD
cord-258708-da6x5rxa	130	21	)	)	-RRB-
cord-258708-da6x5rxa	130	22	.	.	.
cord-258708-da6x5rxa	131	1	Indeed	indeed	RB
cord-258708-da6x5rxa	131	2	,	,	,
cord-258708-da6x5rxa	131	3	activation	activation	NN
cord-258708-da6x5rxa	131	4	of	of	IN
cord-258708-da6x5rxa	131	5	ADAM-17	adam-17	CD
cord-258708-da6x5rxa	131	6	by	by	IN
cord-258708-da6x5rxa	131	7	Ang	Ang	NNP
cord-258708-da6x5rxa	131	8	II	II	NNP
cord-258708-da6x5rxa	131	9	,	,	,
cord-258708-da6x5rxa	131	10	and	and	CC
cord-258708-da6x5rxa	131	11	SARS	SARS	NNP
cord-258708-da6x5rxa	131	12	-	-	HYPH
cord-258708-da6x5rxa	131	13	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	131	14	binding	binding	NN
cord-258708-da6x5rxa	131	15	leads	lead	VBZ
cord-258708-da6x5rxa	131	16	to	to	IN
cord-258708-da6x5rxa	131	17	a	a	DT
cord-258708-da6x5rxa	131	18	loss	loss	NN
cord-258708-da6x5rxa	131	19	of	of	IN
cord-258708-da6x5rxa	131	20	membrane	membrane	NN
cord-258708-da6x5rxa	131	21	-	-	HYPH
cord-258708-da6x5rxa	131	22	bound	bind	VBN
cord-258708-da6x5rxa	131	23	ACE2	ACE2	NNP
cord-258708-da6x5rxa	131	24	,	,	,
cord-258708-da6x5rxa	131	25	and	and	CC
cord-258708-da6x5rxa	131	26	its	-PRON-	PRP$
cord-258708-da6x5rxa	131	27	release	release	NN
cord-258708-da6x5rxa	131	28	into	into	IN
cord-258708-da6x5rxa	131	29	the	the	DT
cord-258708-da6x5rxa	131	30	circulation	circulation	NN
cord-258708-da6x5rxa	131	31	(	(	-LRB-
cord-258708-da6x5rxa	131	32	Figure	figure	NN
cord-258708-da6x5rxa	131	33	2	2	CD
cord-258708-da6x5rxa	131	34	)	)	-RRB-
cord-258708-da6x5rxa	131	35	.	.	.
cord-258708-da6x5rxa	132	1	However	however	RB
cord-258708-da6x5rxa	132	2	,	,	,
cord-258708-da6x5rxa	132	3	intracellular	intracellular	JJ
cord-258708-da6x5rxa	132	4	ACE	ace	NN
cord-258708-da6x5rxa	132	5	levels	level	NNS
cord-258708-da6x5rxa	132	6	are	be	VBP
cord-258708-da6x5rxa	132	7	not	not	RB
cord-258708-da6x5rxa	132	8	depleted	deplete	VBN
cord-258708-da6x5rxa	132	9	(	(	-LRB-
cord-258708-da6x5rxa	132	10	56	56	CD
cord-258708-da6x5rxa	132	11	)	)	-RRB-
cord-258708-da6x5rxa	132	12	.	.	.
cord-258708-da6x5rxa	133	1	These	these	DT
cord-258708-da6x5rxa	133	2	conditions	condition	NNS
cord-258708-da6x5rxa	133	3	limit	limit	VBP
cord-258708-da6x5rxa	133	4	the	the	DT
cord-258708-da6x5rxa	133	5	effects	effect	NNS
cord-258708-da6x5rxa	133	6	of	of	IN
cord-258708-da6x5rxa	133	7	Ang	Ang	NNP
cord-258708-da6x5rxa	133	8	II	II	NNP
cord-258708-da6x5rxa	133	9	diverse	diverse	JJ
cord-258708-da6x5rxa	133	10	in	in	IN
cord-258708-da6x5rxa	133	11	tissues	tissue	NNS
cord-258708-da6x5rxa	133	12	,	,	,
cord-258708-da6x5rxa	133	13	culminating	culminate	VBG
cord-258708-da6x5rxa	133	14	in	in	IN
cord-258708-da6x5rxa	133	15	CV	CV	NNP
cord-258708-da6x5rxa	133	16	,	,	,
cord-258708-da6x5rxa	133	17	renal	renal	JJ
cord-258708-da6x5rxa	133	18	,	,	,
cord-258708-da6x5rxa	133	19	and	and	CC
cord-258708-da6x5rxa	133	20	lung	lung	NN
cord-258708-da6x5rxa	133	21	diseases	disease	NNS
cord-258708-da6x5rxa	133	22	.	.	.
cord-258708-da6x5rxa	134	1	Higher	high	JJR
cord-258708-da6x5rxa	134	2	plasma	plasma	NN
cord-258708-da6x5rxa	134	3	ACE2	ACE2	NNP
cord-258708-da6x5rxa	134	4	levels	level	NNS
cord-258708-da6x5rxa	134	5	were	be	VBD
cord-258708-da6x5rxa	134	6	associated	associate	VBN
cord-258708-da6x5rxa	134	7	with	with	IN
cord-258708-da6x5rxa	134	8	a	a	DT
cord-258708-da6x5rxa	134	9	history	history	NN
cord-258708-da6x5rxa	134	10	of	of	IN
cord-258708-da6x5rxa	134	11	atrial	atrial	JJ
cord-258708-da6x5rxa	134	12	fibrillation	fibrillation	NN
cord-258708-da6x5rxa	134	13	,	,	,
cord-258708-da6x5rxa	134	14	and	and	CC
cord-258708-da6x5rxa	134	15	coronary	coronary	JJ
cord-258708-da6x5rxa	134	16	artery	artery	NN
cord-258708-da6x5rxa	134	17	bypass	bypass	NN
cord-258708-da6x5rxa	134	18	graft	graft	NN
cord-258708-da6x5rxa	134	19	,	,	,
cord-258708-da6x5rxa	134	20	and	and	CC
cord-258708-da6x5rxa	134	21	elevated	elevated	JJ
cord-258708-da6x5rxa	134	22	heart	heart	NN
cord-258708-da6x5rxa	134	23	rate	rate	NN
cord-258708-da6x5rxa	134	24	specially	specially	RB
cord-258708-da6x5rxa	134	25	in	in	IN
cord-258708-da6x5rxa	134	26	man	man	NN
cord-258708-da6x5rxa	134	27	(	(	-LRB-
cord-258708-da6x5rxa	134	28	14	14	CD
cord-258708-da6x5rxa	134	29	)	)	-RRB-
cord-258708-da6x5rxa	134	30	.	.	.
cord-258708-da6x5rxa	135	1	Moreover	moreover	RB
cord-258708-da6x5rxa	135	2	,	,	,
cord-258708-da6x5rxa	135	3	reduced	reduce	VBN
cord-258708-da6x5rxa	135	4	ACE2	ACE2	NNP
cord-258708-da6x5rxa	135	5	levels	level	NNS
cord-258708-da6x5rxa	135	6	in	in	IN
cord-258708-da6x5rxa	135	7	plasma	plasma	NN
cord-258708-da6x5rxa	135	8	was	be	VBD
cord-258708-da6x5rxa	135	9	associated	associate	VBN
cord-258708-da6x5rxa	135	10	with	with	IN
cord-258708-da6x5rxa	135	11	higher	high	JJR
cord-258708-da6x5rxa	135	12	left	left	JJ
cord-258708-da6x5rxa	135	13	ventricular	ventricular	JJ
cord-258708-da6x5rxa	135	14	ejection	ejection	NN
cord-258708-da6x5rxa	135	15	fraction	fraction	NN
cord-258708-da6x5rxa	135	16	,	,	,
cord-258708-da6x5rxa	135	17	and	and	CC
cord-258708-da6x5rxa	135	18	systolic	systolic	JJ
cord-258708-da6x5rxa	135	19	blood	blood	NN
cord-258708-da6x5rxa	135	20	pressure	pressure	NN
cord-258708-da6x5rxa	135	21	(	(	-LRB-
cord-258708-da6x5rxa	135	22	57	57	CD
cord-258708-da6x5rxa	135	23	)	)	-RRB-
cord-258708-da6x5rxa	135	24	.	.	.
cord-258708-da6x5rxa	136	1	In	in	IN
cord-258708-da6x5rxa	136	2	summary	summary	NN
cord-258708-da6x5rxa	136	3	,	,	,
cord-258708-da6x5rxa	136	4	there	there	EX
cord-258708-da6x5rxa	136	5	is	be	VBZ
cord-258708-da6x5rxa	136	6	a	a	DT
cord-258708-da6x5rxa	136	7	mounting	mount	VBG
cord-258708-da6x5rxa	136	8	evidence	evidence	NN
cord-258708-da6x5rxa	136	9	implicating	implicate	VBG
cord-258708-da6x5rxa	136	10	an	an	DT
cord-258708-da6x5rxa	136	11	excessive	excessive	JJ
cord-258708-da6x5rxa	136	12	cytokine	cytokine	NN
cord-258708-da6x5rxa	136	13	storm	storm	NN
cord-258708-da6x5rxa	136	14	with	with	IN
cord-258708-da6x5rxa	136	15	the	the	DT
cord-258708-da6x5rxa	136	16	pathophysiology	pathophysiology	NN
cord-258708-da6x5rxa	136	17	of	of	IN
cord-258708-da6x5rxa	136	18	severe	severe	JJ
cord-258708-da6x5rxa	136	19	COVID-19	covid-19	NN
cord-258708-da6x5rxa	136	20	,	,	,
cord-258708-da6x5rxa	136	21	where	where	WRB
cord-258708-da6x5rxa	136	22	systemic	systemic	JJ
cord-258708-da6x5rxa	136	23	inflammation	inflammation	NN
cord-258708-da6x5rxa	136	24	potentiates	potentiate	VBZ
cord-258708-da6x5rxa	136	25	/	/	,
cord-258708-da6x5rxa	136	26	complicates	complicate	VBZ
cord-258708-da6x5rxa	136	27	the	the	DT
cord-258708-da6x5rxa	136	28	coexisting	coexist	VBG
cord-258708-da6x5rxa	136	29	CVD	CVD	NNP
cord-258708-da6x5rxa	136	30	in	in	IN
cord-258708-da6x5rxa	136	31	these	these	DT
cord-258708-da6x5rxa	136	32	patients	patient	NNS
cord-258708-da6x5rxa	136	33	(	(	-LRB-
cord-258708-da6x5rxa	136	34	58	58	CD
cord-258708-da6x5rxa	136	35	)	)	-RRB-
cord-258708-da6x5rxa	136	36	.	.	.
cord-258708-da6x5rxa	137	1	Such	such	JJ
cord-258708-da6x5rxa	137	2	complications	complication	NNS
cord-258708-da6x5rxa	137	3	included	include	VBD
cord-258708-da6x5rxa	137	4	hypertension	hypertension	NN
cord-258708-da6x5rxa	137	5	,	,	,
cord-258708-da6x5rxa	137	6	heart	heart	NN
cord-258708-da6x5rxa	137	7	failure	failure	NN
cord-258708-da6x5rxa	137	8	,	,	,
cord-258708-da6x5rxa	137	9	myocardial	myocardial	JJ
cord-258708-da6x5rxa	137	10	injury	injury	NN
cord-258708-da6x5rxa	137	11	,	,	,
cord-258708-da6x5rxa	137	12	and	and	CC
cord-258708-da6x5rxa	137	13	atherosclerosis	atherosclerosis	NN
cord-258708-da6x5rxa	137	14	(	(	-LRB-
cord-258708-da6x5rxa	137	15	59	59	CD
cord-258708-da6x5rxa	137	16	)	)	-RRB-
cord-258708-da6x5rxa	137	17	.	.	.
cord-258708-da6x5rxa	138	1	In	in	IN
cord-258708-da6x5rxa	138	2	these	these	DT
cord-258708-da6x5rxa	138	3	patients	patient	NNS
cord-258708-da6x5rxa	138	4	,	,	,
cord-258708-da6x5rxa	138	5	the	the	DT
cord-258708-da6x5rxa	138	6	pathogenic	pathogenic	JJ
cord-258708-da6x5rxa	138	7	mechanism	mechanism	NN
cord-258708-da6x5rxa	138	8	that	that	WDT
cord-258708-da6x5rxa	138	9	produces	produce	VBZ
cord-258708-da6x5rxa	138	10	CV	cv	NN
cord-258708-da6x5rxa	138	11	complications	complication	NNS
cord-258708-da6x5rxa	138	12	seem	seem	VBP
cord-258708-da6x5rxa	138	13	to	to	TO
cord-258708-da6x5rxa	138	14	be	be	VB
cord-258708-da6x5rxa	138	15	remarkably	remarkably	RB
cord-258708-da6x5rxa	138	16	complex	complex	JJ
cord-258708-da6x5rxa	138	17	.	.	.
cord-258708-da6x5rxa	139	1	Significance	significance	NN
cord-258708-da6x5rxa	139	2	of	of	IN
cord-258708-da6x5rxa	139	3	the	the	DT
cord-258708-da6x5rxa	139	4	SARS	SARS	NNP
cord-258708-da6x5rxa	139	5	-	-	HYPH
cord-258708-da6x5rxa	139	6	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	139	7	infection	infection	NN
cord-258708-da6x5rxa	139	8	in	in	IN
cord-258708-da6x5rxa	139	9	the	the	DT
cord-258708-da6x5rxa	139	10	CV	cv	NN
cord-258708-da6x5rxa	139	11	system	system	NN
cord-258708-da6x5rxa	139	12	is	be	VBZ
cord-258708-da6x5rxa	139	13	reflected	reflect	VBN
cord-258708-da6x5rxa	139	14	through	through	IN
cord-258708-da6x5rxa	139	15	incidences	incidence	NNS
cord-258708-da6x5rxa	139	16	of	of	IN
cord-258708-da6x5rxa	139	17	acute	acute	JJ
cord-258708-da6x5rxa	139	18	myocardial	myocardial	JJ
cord-258708-da6x5rxa	139	19	injury	injury	NN
cord-258708-da6x5rxa	139	20	,	,	,
cord-258708-da6x5rxa	139	21	arrhythmias	arrhythmias	RB
cord-258708-da6x5rxa	139	22	,	,	,
cord-258708-da6x5rxa	139	23	ACS	ACS	NNP
cord-258708-da6x5rxa	139	24	,	,	,
cord-258708-da6x5rxa	139	25	sepsis	sepsis	NN
cord-258708-da6x5rxa	139	26	,	,	,
cord-258708-da6x5rxa	139	27	septic	septic	JJ
cord-258708-da6x5rxa	139	28	shock	shock	NN
cord-258708-da6x5rxa	139	29	,	,	,
cord-258708-da6x5rxa	139	30	viral	viral	JJ
cord-258708-da6x5rxa	139	31	myocarditis	myocarditis	NN
cord-258708-da6x5rxa	139	32	,	,	,
cord-258708-da6x5rxa	139	33	and	and	CC
cord-258708-da6x5rxa	139	34	heart	heart	NN
cord-258708-da6x5rxa	139	35	failure	failure	NN
cord-258708-da6x5rxa	139	36	.	.	.
cord-258708-da6x5rxa	140	1	Myocardial	myocardial	JJ
cord-258708-da6x5rxa	140	2	injury	injury	NN
cord-258708-da6x5rxa	140	3	underscore	underscore	VBP
cord-258708-da6x5rxa	140	4	significant	significant	JJ
cord-258708-da6x5rxa	140	5	association	association	NN
cord-258708-da6x5rxa	140	6	with	with	IN
cord-258708-da6x5rxa	140	7	fatal	fatal	JJ
cord-258708-da6x5rxa	140	8	outcomes	outcome	NNS
cord-258708-da6x5rxa	140	9	,	,	,
cord-258708-da6x5rxa	140	10	whereas	whereas	IN
cord-258708-da6x5rxa	140	11	the	the	DT
cord-258708-da6x5rxa	140	12	prognosis	prognosis	NN
cord-258708-da6x5rxa	140	13	of	of	IN
cord-258708-da6x5rxa	140	14	patients	patient	NNS
cord-258708-da6x5rxa	140	15	with	with	IN
cord-258708-da6x5rxa	140	16	underlying	underlie	VBG
cord-258708-da6x5rxa	140	17	CVD	CVD	NNP
cord-258708-da6x5rxa	140	18	but	but	CC
cord-258708-da6x5rxa	140	19	without	without	IN
cord-258708-da6x5rxa	140	20	myocardial	myocardial	JJ
cord-258708-da6x5rxa	140	21	injury	injury	NN
cord-258708-da6x5rxa	140	22	seems	seem	VBZ
cord-258708-da6x5rxa	140	23	quite	quite	RB
cord-258708-da6x5rxa	140	24	favorable	favorable	JJ
cord-258708-da6x5rxa	140	25	.	.	.
cord-258708-da6x5rxa	141	1	We	-PRON-	PRP
cord-258708-da6x5rxa	141	2	speculate	speculate	VBP
cord-258708-da6x5rxa	141	3	that	that	IN
cord-258708-da6x5rxa	141	4	while	while	IN
cord-258708-da6x5rxa	141	5	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	141	6	disease	disease	NN
cord-258708-da6x5rxa	141	7	begins	begin	VBZ
cord-258708-da6x5rxa	141	8	with	with	IN
cord-258708-da6x5rxa	141	9	respiratory	respiratory	JJ
cord-258708-da6x5rxa	141	10	condition	condition	NN
cord-258708-da6x5rxa	141	11	,	,	,
cord-258708-da6x5rxa	141	12	it	-PRON-	PRP
cord-258708-da6x5rxa	141	13	hastily	hastily	RB
cord-258708-da6x5rxa	141	14	involves	involve	VBZ
cord-258708-da6x5rxa	141	15	the	the	DT
cord-258708-da6x5rxa	141	16	CV	cv	NN
cord-258708-da6x5rxa	141	17	system	system	NN
cord-258708-da6x5rxa	141	18	through	through	IN
cord-258708-da6x5rxa	141	19	an	an	DT
cord-258708-da6x5rxa	141	20	imbalance	imbalance	NN
cord-258708-da6x5rxa	141	21	of	of	IN
cord-258708-da6x5rxa	141	22	the	the	DT
cord-258708-da6x5rxa	141	23	renin	renin	NN
cord-258708-da6x5rxa	141	24	-	-	HYPH
cord-258708-da6x5rxa	141	25	Ang	Ang	NNP
cord-258708-da6x5rxa	141	26	system	system	NN
cord-258708-da6x5rxa	141	27	mediated	mediate	VBN
cord-258708-da6x5rxa	141	28	by	by	IN
cord-258708-da6x5rxa	141	29	ACE2	ACE2	NNP
cord-258708-da6x5rxa	141	30	depletion	depletion	NN
cord-258708-da6x5rxa	141	31	.	.	.
cord-258708-da6x5rxa	142	1	This	this	DT
cord-258708-da6x5rxa	142	2	mechanism	mechanism	NN
cord-258708-da6x5rxa	142	3	possibly	possibly	RB
cord-258708-da6x5rxa	142	4	complicates	complicate	VBZ
cord-258708-da6x5rxa	142	5	the	the	DT
cord-258708-da6x5rxa	142	6	clinical	clinical	JJ
cord-258708-da6x5rxa	142	7	course	course	NN
cord-258708-da6x5rxa	142	8	through	through	IN
cord-258708-da6x5rxa	142	9	the	the	DT
cord-258708-da6x5rxa	142	10	inflammatory	inflammatory	JJ
cord-258708-da6x5rxa	142	11	response	response	NN
cord-258708-da6x5rxa	142	12	,	,	,
cord-258708-da6x5rxa	142	13	endothelial	endothelial	JJ
cord-258708-da6x5rxa	142	14	dysfunction	dysfunction	NN
cord-258708-da6x5rxa	142	15	,	,	,
cord-258708-da6x5rxa	142	16	and	and	CC
cord-258708-da6x5rxa	142	17	microvascular	microvascular	JJ
cord-258708-da6x5rxa	142	18	damage	damage	NN
cord-258708-da6x5rxa	142	19	where	where	WRB
cord-258708-da6x5rxa	142	20	inflammation	inflammation	NN
cord-258708-da6x5rxa	142	21	may	may	MD
cord-258708-da6x5rxa	142	22	be	be	VB
cord-258708-da6x5rxa	142	23	associated	associate	VBN
cord-258708-da6x5rxa	142	24	with	with	IN
cord-258708-da6x5rxa	142	25	myocardial	myocardial	JJ
cord-258708-da6x5rxa	142	26	injury	injury	NN
cord-258708-da6x5rxa	142	27	.	.	.
cord-258708-da6x5rxa	143	1	However	however	RB
cord-258708-da6x5rxa	143	2	,	,	,
cord-258708-da6x5rxa	143	3	additional	additional	JJ
cord-258708-da6x5rxa	143	4	study	study	NN
cord-258708-da6x5rxa	143	5	of	of	IN
cord-258708-da6x5rxa	143	6	these	these	DT
cord-258708-da6x5rxa	143	7	mechanisms	mechanism	NNS
cord-258708-da6x5rxa	143	8	is	be	VBZ
cord-258708-da6x5rxa	143	9	clearly	clearly	RB
cord-258708-da6x5rxa	143	10	needed	need	VBN
cord-258708-da6x5rxa	143	11	and	and	CC
cord-258708-da6x5rxa	143	12	may	may	MD
cord-258708-da6x5rxa	143	13	influence	influence	VB
cord-258708-da6x5rxa	143	14	the	the	DT
cord-258708-da6x5rxa	143	15	search	search	NN
cord-258708-da6x5rxa	143	16	for	for	IN
cord-258708-da6x5rxa	143	17	ways	way	NNS
cord-258708-da6x5rxa	143	18	to	to	TO
cord-258708-da6x5rxa	143	19	prevent	prevent	VB
cord-258708-da6x5rxa	143	20	myocardial	myocardial	JJ
cord-258708-da6x5rxa	143	21	complications	complication	NNS
cord-258708-da6x5rxa	143	22	.	.	.
cord-258708-da6x5rxa	144	1	More	More	JJR
cord-258708-da6x5rxa	144	2	evidence	evidence	NN
cord-258708-da6x5rxa	144	3	from	from	IN
cord-258708-da6x5rxa	144	4	laboratories	laboratory	NNS
cord-258708-da6x5rxa	144	5	,	,	,
cord-258708-da6x5rxa	144	6	and	and	CC
cord-258708-da6x5rxa	144	7	clinical	clinical	JJ
cord-258708-da6x5rxa	144	8	research	research	NN
cord-258708-da6x5rxa	144	9	is	be	VBZ
cord-258708-da6x5rxa	144	10	needed	need	VBN
cord-258708-da6x5rxa	144	11	to	to	TO
cord-258708-da6x5rxa	144	12	learn	learn	VB
cord-258708-da6x5rxa	144	13	more	more	JJR
cord-258708-da6x5rxa	144	14	about	about	IN
cord-258708-da6x5rxa	144	15	the	the	DT
cord-258708-da6x5rxa	144	16	impact	impact	NN
cord-258708-da6x5rxa	144	17	of	of	IN
cord-258708-da6x5rxa	144	18	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	144	19	on	on	IN
cord-258708-da6x5rxa	144	20	the	the	DT
cord-258708-da6x5rxa	144	21	CV	cv	NN
cord-258708-da6x5rxa	144	22	system	system	NN
cord-258708-da6x5rxa	144	23	.	.	.
cord-258708-da6x5rxa	145	1	This	this	DT
cord-258708-da6x5rxa	145	2	research	research	NN
cord-258708-da6x5rxa	145	3	received	receive	VBD
cord-258708-da6x5rxa	145	4	no	no	DT
cord-258708-da6x5rxa	145	5	funding	funding	NN
cord-258708-da6x5rxa	145	6	.	.	.
cord-258708-da6x5rxa	146	1	The	the	DT
cord-258708-da6x5rxa	146	2	author	author	NN
cord-258708-da6x5rxa	146	3	declares	declare	VBZ
cord-258708-da6x5rxa	146	4	no	no	DT
cord-258708-da6x5rxa	146	5	conflict	conflict	NN
cord-258708-da6x5rxa	146	6	of	of	IN
cord-258708-da6x5rxa	146	7	interest	interest	NN
cord-258708-da6x5rxa	146	8	.	.	.
cord-258708-da6x5rxa	147	1	infection	infection	NN
cord-258708-da6x5rxa	147	2	.	.	.
cord-258708-da6x5rxa	148	1	1	1	LS
cord-258708-da6x5rxa	148	2	)	)	-RRB-
cord-258708-da6x5rxa	149	1	ACE2	ACE2	NNP
cord-258708-da6x5rxa	149	2	binds	bind	VBZ
cord-258708-da6x5rxa	149	3	to	to	IN
cord-258708-da6x5rxa	149	4	the	the	DT
cord-258708-da6x5rxa	149	5	viral	viral	JJ
cord-258708-da6x5rxa	149	6	S	S	NNP
cord-258708-da6x5rxa	149	7	protein	protein	NN
cord-258708-da6x5rxa	149	8	,	,	,
cord-258708-da6x5rxa	149	9	which	which	WDT
cord-258708-da6x5rxa	149	10	is	be	VBZ
cord-258708-da6x5rxa	149	11	cleaved	cleave	VBN
cord-258708-da6x5rxa	149	12	into	into	IN
cord-258708-da6x5rxa	149	13	two	two	CD
cord-258708-da6x5rxa	149	14	subunits	subunit	NNS
cord-258708-da6x5rxa	149	15	,	,	,
cord-258708-da6x5rxa	149	16	S1	S1	NNP
cord-258708-da6x5rxa	149	17	and	and	CC
cord-258708-da6x5rxa	149	18	S2	S2	NNP
cord-258708-da6x5rxa	149	19	,	,	,
cord-258708-da6x5rxa	149	20	by	by	IN
cord-258708-da6x5rxa	149	21	an	an	DT
cord-258708-da6x5rxa	149	22	extracellular	extracellular	JJ
cord-258708-da6x5rxa	149	23	protease	protease	NN
cord-258708-da6x5rxa	149	24	.	.	.
cord-258708-da6x5rxa	150	1	While	while	IN
cord-258708-da6x5rxa	150	2	S1	s1	NN
cord-258708-da6x5rxa	150	3	binds	bind	VBZ
cord-258708-da6x5rxa	150	4	to	to	IN
cord-258708-da6x5rxa	150	5	ACE2	ACE2	NNP
cord-258708-da6x5rxa	150	6	,	,	,
cord-258708-da6x5rxa	150	7	S2	S2	NNP
cord-258708-da6x5rxa	150	8	is	be	VBZ
cord-258708-da6x5rxa	150	9	further	further	RB
cord-258708-da6x5rxa	150	10	cleaved	cleave	VBN
cord-258708-da6x5rxa	150	11	,	,	,
cord-258708-da6x5rxa	150	12	and	and	CC
cord-258708-da6x5rxa	150	13	activated	activate	VBN
cord-258708-da6x5rxa	150	14	by	by	IN
cord-258708-da6x5rxa	150	15	serine	serine	NN
cord-258708-da6x5rxa	150	16	protease	protease	NN
cord-258708-da6x5rxa	150	17	TMPRSS2	TMPRSS2	NNP
cord-258708-da6x5rxa	150	18	.	.	.
cord-258708-da6x5rxa	151	1	Together	together	RB
cord-258708-da6x5rxa	151	2	these	these	DT
cord-258708-da6x5rxa	151	3	actions	action	NNS
cord-258708-da6x5rxa	151	4	result	result	VBP
cord-258708-da6x5rxa	151	5	in	in	IN
cord-258708-da6x5rxa	151	6	host	host	NN
cord-258708-da6x5rxa	151	7	-	-	HYPH
cord-258708-da6x5rxa	151	8	viral	viral	JJ
cord-258708-da6x5rxa	151	9	membrane	membrane	NN
cord-258708-da6x5rxa	151	10	fusion	fusion	NN
cord-258708-da6x5rxa	151	11	,	,	,
cord-258708-da6x5rxa	151	12	and	and	CC
cord-258708-da6x5rxa	151	13	the	the	DT
cord-258708-da6x5rxa	151	14	release	release	NN
cord-258708-da6x5rxa	151	15	of	of	IN
cord-258708-da6x5rxa	151	16	the	the	DT
cord-258708-da6x5rxa	151	17	RNA	RNA	NNP
cord-258708-da6x5rxa	151	18	genome	genome	NN
cord-258708-da6x5rxa	151	19	into	into	IN
cord-258708-da6x5rxa	151	20	the	the	DT
cord-258708-da6x5rxa	151	21	host	host	NN
cord-258708-da6x5rxa	151	22	cell	cell	NN
cord-258708-da6x5rxa	151	23	cytoplasm	cytoplasm	NN
cord-258708-da6x5rxa	151	24	,	,	,
cord-258708-da6x5rxa	151	25	2	2	CD
cord-258708-da6x5rxa	151	26	)	)	-RRB-
cord-258708-da6x5rxa	151	27	Translation	translation	NN
cord-258708-da6x5rxa	151	28	of	of	IN
cord-258708-da6x5rxa	151	29	structural	structural	JJ
cord-258708-da6x5rxa	151	30	,	,	,
cord-258708-da6x5rxa	151	31	and	and	CC
cord-258708-da6x5rxa	151	32	non	non	JJ
cord-258708-da6x5rxa	151	33	-	-	JJ
cord-258708-da6x5rxa	151	34	structural	structural	JJ
cord-258708-da6x5rxa	151	35	proteins	protein	NNS
cord-258708-da6x5rxa	151	36	as	as	IN
cord-258708-da6x5rxa	151	37	follows	follow	VBZ
cord-258708-da6x5rxa	151	38	:	:	:
cord-258708-da6x5rxa	151	39	ORF1a	ORF1a	NNP
cord-258708-da6x5rxa	151	40	,	,	,
cord-258708-da6x5rxa	151	41	and	and	CC
cord-258708-da6x5rxa	151	42	ORF1ab	ORF1ab	NNP
cord-258708-da6x5rxa	151	43	proteins	protein	NNS
cord-258708-da6x5rxa	151	44	are	be	VBP
cord-258708-da6x5rxa	151	45	translated	translate	VBN
cord-258708-da6x5rxa	151	46	to	to	TO
cord-258708-da6x5rxa	151	47	yield	yield	VB
cord-258708-da6x5rxa	151	48	pp1a	pp1a	NNP
cord-258708-da6x5rxa	151	49	,	,	,
cord-258708-da6x5rxa	151	50	and	and	CC
cord-258708-da6x5rxa	151	51	pp1ab	pp1ab	NNP
cord-258708-da6x5rxa	151	52	polyproteins	polyprotein	NNS
cord-258708-da6x5rxa	151	53	.	.	.
cord-258708-da6x5rxa	152	1	These	these	DT
cord-258708-da6x5rxa	152	2	are	be	VBP
cord-258708-da6x5rxa	152	3	cleaved	cleave	VBN
cord-258708-da6x5rxa	152	4	by	by	IN
cord-258708-da6x5rxa	152	5	proteases	protease	NNS
cord-258708-da6x5rxa	152	6	that	that	WDT
cord-258708-da6x5rxa	152	7	are	be	VBP
cord-258708-da6x5rxa	152	8	encoded	encode	VBN
cord-258708-da6x5rxa	152	9	by	by	IN
cord-258708-da6x5rxa	152	10	ORF1a	ORF1a	NNP
cord-258708-da6x5rxa	152	11	to	to	TO
cord-258708-da6x5rxa	152	12	produce	produce	VB
cord-258708-da6x5rxa	152	13	16	16	CD
cord-258708-da6x5rxa	152	14	nonstructural	nonstructural	JJ
cord-258708-da6x5rxa	152	15	proteins	protein	NNS
cord-258708-da6x5rxa	152	16	.	.	.
cord-258708-da6x5rxa	153	1	The	the	DT
cord-258708-da6x5rxa	153	2	polyproteins	polyprotein	NNS
cord-258708-da6x5rxa	153	3	(	(	-LRB-
cord-258708-da6x5rxa	153	4	pp1a	pp1a	XX
cord-258708-da6x5rxa	153	5	,	,	,
cord-258708-da6x5rxa	153	6	and	and	CC
cord-258708-da6x5rxa	153	7	pp1ab	pp1ab	NNP
cord-258708-da6x5rxa	153	8	)	)	-RRB-
cord-258708-da6x5rxa	153	9	are	be	VBP
cord-258708-da6x5rxa	153	10	cleaved	cleave	VBN
cord-258708-da6x5rxa	153	11	into	into	IN
cord-258708-da6x5rxa	153	12	16	16	CD
cord-258708-da6x5rxa	153	13	non	non	JJ
cord-258708-da6x5rxa	153	14	-	-	JJ
cord-258708-da6x5rxa	153	15	structural	structural	JJ
cord-258708-da6x5rxa	153	16	effector	effector	NN
cord-258708-da6x5rxa	153	17	proteins	protein	NNS
cord-258708-da6x5rxa	153	18	by	by	IN
cord-258708-da6x5rxa	153	19	3CLpro	3clpro	CD
cord-258708-da6x5rxa	153	20	,	,	,
cord-258708-da6x5rxa	153	21	and	and	CC
cord-258708-da6x5rxa	153	22	PLpro	PLpro	NNP
cord-258708-da6x5rxa	153	23	,	,	,
cord-258708-da6x5rxa	153	24	3	3	LS
cord-258708-da6x5rxa	153	25	)	)	-RRB-
cord-258708-da6x5rxa	153	26	allowing	allow	VBG
cord-258708-da6x5rxa	153	27	them	-PRON-	PRP
cord-258708-da6x5rxa	153	28	to	to	TO
cord-258708-da6x5rxa	153	29	form	form	VB
cord-258708-da6x5rxa	153	30	the	the	DT
cord-258708-da6x5rxa	153	31	replication	replication	NN
cord-258708-da6x5rxa	153	32	complex	complex	NN
cord-258708-da6x5rxa	153	33	together	together	RB
cord-258708-da6x5rxa	153	34	with	with	IN
cord-258708-da6x5rxa	153	35	the	the	DT
cord-258708-da6x5rxa	153	36	RNA	RNA	NNP
cord-258708-da6x5rxa	153	37	polymerase	polymerase	NN
cord-258708-da6x5rxa	153	38	,	,	,
cord-258708-da6x5rxa	153	39	which	which	WDT
cord-258708-da6x5rxa	153	40	synthesizes	synthesize	VBZ
cord-258708-da6x5rxa	153	41	a	a	DT
cord-258708-da6x5rxa	153	42	full	full	JJ
cord-258708-da6x5rxa	153	43	-	-	HYPH
cord-258708-da6x5rxa	153	44	length	length	NN
cord-258708-da6x5rxa	153	45	negative	negative	JJ
cord-258708-da6x5rxa	153	46	RNA	RNA	NNP
cord-258708-da6x5rxa	153	47	strand	strand	NN
cord-258708-da6x5rxa	153	48	template	template	NN
cord-258708-da6x5rxa	153	49	,	,	,
cord-258708-da6x5rxa	153	50	4	4	CD
cord-258708-da6x5rxa	153	51	)	)	-RRB-
cord-258708-da6x5rxa	154	1	This	this	DT
cord-258708-da6x5rxa	154	2	template	template	NN
cord-258708-da6x5rxa	154	3	is	be	VBZ
cord-258708-da6x5rxa	154	4	used	use	VBN
cord-258708-da6x5rxa	154	5	to	to	TO
cord-258708-da6x5rxa	154	6	replicate	replicate	VB
cord-258708-da6x5rxa	154	7	the	the	DT
cord-258708-da6x5rxa	154	8	complete	complete	JJ
cord-258708-da6x5rxa	154	9	RNA	RNA	NNP
cord-258708-da6x5rxa	154	10	genome	genome	NN
cord-258708-da6x5rxa	154	11	,	,	,
cord-258708-da6x5rxa	154	12	and	and	CC
cord-258708-da6x5rxa	154	13	generate	generate	VB
cord-258708-da6x5rxa	154	14	the	the	DT
cord-258708-da6x5rxa	154	15	individual	individual	JJ
cord-258708-da6x5rxa	154	16	sub	sub	JJ
cord-258708-da6x5rxa	154	17	-	-	JJ
cord-258708-da6x5rxa	154	18	genomic	genomic	JJ
cord-258708-da6x5rxa	154	19	mRNA	mrna	NN
cord-258708-da6x5rxa	154	20	needed	need	VBN
cord-258708-da6x5rxa	154	21	for	for	IN
cord-258708-da6x5rxa	154	22	the	the	DT
cord-258708-da6x5rxa	154	23	translation	translation	NN
cord-258708-da6x5rxa	154	24	of	of	IN
cord-258708-da6x5rxa	154	25	the	the	DT
cord-258708-da6x5rxa	154	26	viral	viral	JJ
cord-258708-da6x5rxa	154	27	structural	structural	JJ
cord-258708-da6x5rxa	154	28	,	,	,
cord-258708-da6x5rxa	154	29	and	and	CC
cord-258708-da6x5rxa	154	30	accessory	accessory	NN
cord-258708-da6x5rxa	154	31	proteins	protein	NNS
cord-258708-da6x5rxa	154	32	,	,	,
cord-258708-da6x5rxa	154	33	5	5	CD
cord-258708-da6x5rxa	154	34	)	)	-RRB-
cord-258708-da6x5rxa	155	1	The	the	DT
cord-258708-da6x5rxa	155	2	newly	newly	RB
cord-258708-da6x5rxa	155	3	synthesized	synthesize	VBN
cord-258708-da6x5rxa	155	4	structural	structural	JJ
cord-258708-da6x5rxa	155	5	,	,	,
cord-258708-da6x5rxa	155	6	and	and	CC
cord-258708-da6x5rxa	155	7	accessory	accessory	NN
cord-258708-da6x5rxa	155	8	proteins	protein	NNS
cord-258708-da6x5rxa	155	9	are	be	VBP
cord-258708-da6x5rxa	155	10	then	then	RB
cord-258708-da6x5rxa	155	11	trafficked	traffic	VBN
cord-258708-da6x5rxa	155	12	from	from	IN
cord-258708-da6x5rxa	155	13	the	the	DT
cord-258708-da6x5rxa	155	14	ER	ER	NNP
cord-258708-da6x5rxa	155	15	through	through	IN
cord-258708-da6x5rxa	155	16	the	the	DT
cord-258708-da6x5rxa	155	17	Golgi	Golgi	NNP
cord-258708-da6x5rxa	155	18	apparatus	apparatus	NN
cord-258708-da6x5rxa	155	19	,	,	,
cord-258708-da6x5rxa	155	20	after	after	IN
cord-258708-da6x5rxa	155	21	which	which	WDT
cord-258708-da6x5rxa	155	22	new	new	JJ
cord-258708-da6x5rxa	155	23	virions	virion	NNS
cord-258708-da6x5rxa	155	24	assemble	assemble	VBP
cord-258708-da6x5rxa	155	25	in	in	IN
cord-258708-da6x5rxa	155	26	bourgeoning	bourgeon	VBG
cord-258708-da6x5rxa	155	27	Golgi	Golgi	NNP
cord-258708-da6x5rxa	155	28	vesicles	vesicle	NNS
cord-258708-da6x5rxa	155	29	,	,	,
cord-258708-da6x5rxa	155	30	6	6	CD
cord-258708-da6x5rxa	155	31	)	)	-RRB-
cord-258708-da6x5rxa	156	1	Finally	finally	RB
cord-258708-da6x5rxa	156	2	,	,	,
cord-258708-da6x5rxa	156	3	the	the	DT
cord-258708-da6x5rxa	156	4	mature	mature	JJ
cord-258708-da6x5rxa	156	5	SARS	SARS	NNP
cord-258708-da6x5rxa	156	6	-	-	HYPH
cord-258708-da6x5rxa	156	7	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	156	8	virions	virion	NNS
cord-258708-da6x5rxa	156	9	are	be	VBP
cord-258708-da6x5rxa	156	10	exocytosed	exocytose	VBN
cord-258708-da6x5rxa	156	11	,	,	,
cord-258708-da6x5rxa	156	12	and	and	CC
cord-258708-da6x5rxa	156	13	released	release	VBN
cord-258708-da6x5rxa	156	14	from	from	IN
cord-258708-da6x5rxa	156	15	the	the	DT
cord-258708-da6x5rxa	156	16	host	host	NN
cord-258708-da6x5rxa	156	17	cell	cell	NN
cord-258708-da6x5rxa	156	18	.	.	.
cord-258708-da6x5rxa	157	1	Also	also	RB
cord-258708-da6x5rxa	157	2	shown	show	VBN
cord-258708-da6x5rxa	157	3	,	,	,
cord-258708-da6x5rxa	157	4	schematic	schematic	JJ
cord-258708-da6x5rxa	157	5	representation	representation	NN
cord-258708-da6x5rxa	157	6	of	of	IN
cord-258708-da6x5rxa	157	7	the	the	DT
cord-258708-da6x5rxa	157	8	RAS	RAS	NNP
cord-258708-da6x5rxa	157	9	-	-	HYPH
cord-258708-da6x5rxa	157	10	pathway	pathway	NN
cord-258708-da6x5rxa	157	11	in	in	IN
cord-258708-da6x5rxa	157	12	which	which	WDT
cord-258708-da6x5rxa	157	13	ACE	ACE	NNP
cord-258708-da6x5rxa	157	14	/	/	SYM
cord-258708-da6x5rxa	157	15	Ang	Ang	NNP
cord-258708-da6x5rxa	157	16	-	-	HYPH
cord-258708-da6x5rxa	157	17	II	II	NNP
cord-258708-da6x5rxa	157	18	,	,	,
cord-258708-da6x5rxa	157	19	and	and	CC
cord-258708-da6x5rxa	157	20	ACE	ACE	NNP
cord-258708-da6x5rxa	157	21	/	/	SYM
cord-258708-da6x5rxa	157	22	Ang	Ang	NNP
cord-258708-da6x5rxa	157	23	1	1	CD
cord-258708-da6x5rxa	157	24	-	-	SYM
cord-258708-da6x5rxa	157	25	7	7	CD
cord-258708-da6x5rxa	157	26	/	/	SYM
cord-258708-da6x5rxa	157	27	Mas	Mas	NNP
cord-258708-da6x5rxa	157	28	-	-	HYPH
cord-258708-da6x5rxa	157	29	axis	axis	NN
cord-258708-da6x5rxa	157	30	.	.	.
cord-258708-da6x5rxa	158	1	Surface	Surface	NNP
cord-258708-da6x5rxa	158	2	ACE2	ACE2	NNP
cord-258708-da6x5rxa	158	3	is	be	VBZ
cord-258708-da6x5rxa	158	4	further	further	RB
cord-258708-da6x5rxa	158	5	down	down	RB
cord-258708-da6x5rxa	158	6	-	-	HYPH
cord-258708-da6x5rxa	158	7	regulated	regulated	JJ
cord-258708-da6x5rxa	158	8	,	,	,
cord-258708-da6x5rxa	158	9	resulting	result	VBG
cord-258708-da6x5rxa	158	10	in	in	IN
cord-258708-da6x5rxa	158	11	unopposed	unopposed	JJ
cord-258708-da6x5rxa	158	12	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	158	13	II	II	NNP
cord-258708-da6x5rxa	158	14	accumulation	accumulation	NN
cord-258708-da6x5rxa	158	15	describing	describe	VBG
cord-258708-da6x5rxa	158	16	the	the	DT
cord-258708-da6x5rxa	158	17	regulatory	regulatory	JJ
cord-258708-da6x5rxa	158	18	role	role	NN
cord-258708-da6x5rxa	158	19	of	of	IN
cord-258708-da6x5rxa	158	20	ACE2-Ang	ACE2-Ang	NNP
cord-258708-da6x5rxa	158	21	1	1	CD
cord-258708-da6x5rxa	158	22	-	-	SYM
cord-258708-da6x5rxa	158	23	7	7	CD
cord-258708-da6x5rxa	158	24	axis	axis	NN
cord-258708-da6x5rxa	158	25	in	in	IN
cord-258708-da6x5rxa	158	26	the	the	DT
cord-258708-da6x5rxa	158	27	cardiovascular	cardiovascular	JJ
cord-258708-da6x5rxa	158	28	homeostasis	homeostasis	NN
cord-258708-da6x5rxa	158	29	.	.	.
cord-258708-da6x5rxa	159	1	Local	local	JJ
cord-258708-da6x5rxa	159	2	activation	activation	NN
cord-258708-da6x5rxa	159	3	of	of	IN
cord-258708-da6x5rxa	159	4	the	the	DT
cord-258708-da6x5rxa	159	5	RAAS	raa	NNS
cord-258708-da6x5rxa	159	6	by	by	IN
cord-258708-da6x5rxa	159	7	SARS	SARS	NNP
cord-258708-da6x5rxa	159	8	-	-	HYPH
cord-258708-da6x5rxa	159	9	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	159	10	spike	spike	NN
cord-258708-da6x5rxa	159	11	may	may	MD
cord-258708-da6x5rxa	159	12	mediate	mediate	VB
cord-258708-da6x5rxa	159	13	lung	lung	NN
cord-258708-da6x5rxa	159	14	injury	injury	NN
cord-258708-da6x5rxa	159	15	,	,	,
cord-258708-da6x5rxa	159	16	and	and	CC
cord-258708-da6x5rxa	159	17	responses	response	NNS
cord-258708-da6x5rxa	159	18	to	to	IN
cord-258708-da6x5rxa	159	19	viral	viral	JJ
cord-258708-da6x5rxa	159	20	insults	insult	NNS
cord-258708-da6x5rxa	159	21	such	such	JJ
cord-258708-da6x5rxa	159	22	as	as	IN
cord-258708-da6x5rxa	159	23	CV	CV	NNP
cord-258708-da6x5rxa	159	24	complications	complication	NNS
cord-258708-da6x5rxa	159	25	.	.	.
cord-258708-da6x5rxa	160	1	ACE	ace	NN
cord-258708-da6x5rxa	160	2	enzyme	enzyme	NN
cord-258708-da6x5rxa	160	3	inhibitors	inhibitor	NNS
cord-258708-da6x5rxa	160	4	and	and	CC
cord-258708-da6x5rxa	160	5	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	160	6	receptor	receptor	NN
cord-258708-da6x5rxa	160	7	blockers	blocker	NNS
cord-258708-da6x5rxa	160	8	(	(	-LRB-
cord-258708-da6x5rxa	160	9	ARBs	arb	NNS
cord-258708-da6x5rxa	160	10	)	)	-RRB-
cord-258708-da6x5rxa	160	11	possibly	possibly	RB
cord-258708-da6x5rxa	160	12	rise	rise	VB
cord-258708-da6x5rxa	160	13	the	the	DT
cord-258708-da6x5rxa	160	14	risk	risk	NN
cord-258708-da6x5rxa	160	15	of	of	IN
cord-258708-da6x5rxa	160	16	severe	severe	JJ
cord-258708-da6x5rxa	160	17	COVID-19	covid-19	JJ
cord-258708-da6x5rxa	160	18	outcomes	outcome	NNS
cord-258708-da6x5rxa	160	19	.	.	.
cord-258708-da6x5rxa	161	1	On	on	IN
cord-258708-da6x5rxa	161	2	the	the	DT
cord-258708-da6x5rxa	161	3	right	right	NN
cord-258708-da6x5rxa	161	4	of	of	IN
cord-258708-da6x5rxa	161	5	the	the	DT
cord-258708-da6x5rxa	161	6	panel	panel	NN
cord-258708-da6x5rxa	161	7	,	,	,
cord-258708-da6x5rxa	161	8	local	local	JJ
cord-258708-da6x5rxa	161	9	complications	complication	NNS
cord-258708-da6x5rxa	161	10	of	of	IN
cord-258708-da6x5rxa	161	11	virus	virus	NN
cord-258708-da6x5rxa	161	12	infection	infection	NN
cord-258708-da6x5rxa	161	13	on	on	IN
cord-258708-da6x5rxa	161	14	cardiovascular	cardiovascular	JJ
cord-258708-da6x5rxa	161	15	system	system	NN
cord-258708-da6x5rxa	161	16	is	be	VBZ
cord-258708-da6x5rxa	161	17	presented	present	VBN
cord-258708-da6x5rxa	161	18	.	.	.
cord-258708-da6x5rxa	162	1	Origin	origin	NN
cord-258708-da6x5rxa	162	2	and	and	CC
cord-258708-da6x5rxa	162	3	evolution	evolution	NN
cord-258708-da6x5rxa	162	4	of	of	IN
cord-258708-da6x5rxa	162	5	pathogenic	pathogenic	JJ
cord-258708-da6x5rxa	162	6	coronaviruses	coronaviruse	NNS
cord-258708-da6x5rxa	163	1	The	the	DT
cord-258708-da6x5rxa	163	2	species	specie	NNS
cord-258708-da6x5rxa	163	3	Severe	severe	JJ
cord-258708-da6x5rxa	163	4	acute	acute	JJ
cord-258708-da6x5rxa	163	5	respiratory	respiratory	JJ
cord-258708-da6x5rxa	163	6	syndrome	syndrome	NN
cord-258708-da6x5rxa	163	7	-	-	HYPH
cord-258708-da6x5rxa	163	8	related	relate	VBN
cord-258708-da6x5rxa	163	9	coronavirus	coronavirus	NN
cord-258708-da6x5rxa	163	10	:	:	:
cord-258708-da6x5rxa	163	11	classifying	classify	VBG
cord-258708-da6x5rxa	163	12	2019-nCoV	2019-ncov	CD
cord-258708-da6x5rxa	163	13	and	and	CC
cord-258708-da6x5rxa	163	14	naming	name	VBG
cord-258708-da6x5rxa	163	15	it	-PRON-	PRP
cord-258708-da6x5rxa	163	16	SARS	SARS	NNP
cord-258708-da6x5rxa	163	17	-	-	HYPH
cord-258708-da6x5rxa	163	18	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	163	19	Coronavirus	Coronavirus	NNP
cord-258708-da6x5rxa	163	20	Disease	Disease	NNP
cord-258708-da6x5rxa	163	21	2019	2019	CD
cord-258708-da6x5rxa	163	22	(	(	-LRB-
cord-258708-da6x5rxa	163	23	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	163	24	)	)	-RRB-
cord-258708-da6x5rxa	163	25	and	and	CC
cord-258708-da6x5rxa	163	26	Cardiovascular	Cardiovascular	NNP
cord-258708-da6x5rxa	163	27	Disease	Disease	NNP
cord-258708-da6x5rxa	163	28	:	:	:
cord-258708-da6x5rxa	164	1	A	a	DT
cord-258708-da6x5rxa	164	2	Viewpoint	viewpoint	NN
cord-258708-da6x5rxa	164	3	on	on	IN
cord-258708-da6x5rxa	164	4	the	the	DT
cord-258708-da6x5rxa	164	5	Potential	potential	JJ
cord-258708-da6x5rxa	164	6	Influence	influence	NN
cord-258708-da6x5rxa	164	7	of	of	IN
cord-258708-da6x5rxa	164	8	Angiotensin	Angiotensin	NNP
cord-258708-da6x5rxa	164	9	-	-	HYPH
cord-258708-da6x5rxa	164	10	Converting	converting	NN
cord-258708-da6x5rxa	165	1	Enzyme	Enzyme	NNP
cord-258708-da6x5rxa	165	2	Inhibitors	Inhibitors	NNP
cord-258708-da6x5rxa	165	3	/	/	SYM
cord-258708-da6x5rxa	165	4	Angiotensin	Angiotensin	NNP
cord-258708-da6x5rxa	165	5	Receptor	Receptor	NNP
cord-258708-da6x5rxa	165	6	Blockers	Blockers	NNP
cord-258708-da6x5rxa	165	7	on	on	IN
cord-258708-da6x5rxa	165	8	Onset	Onset	NNP
cord-258708-da6x5rxa	165	9	and	and	CC
cord-258708-da6x5rxa	165	10	Severity	severity	NN
cord-258708-da6x5rxa	165	11	of	of	IN
cord-258708-da6x5rxa	165	12	Severe	severe	JJ
cord-258708-da6x5rxa	165	13	Acute	acute	JJ
cord-258708-da6x5rxa	165	14	Respiratory	Respiratory	NNP
cord-258708-da6x5rxa	165	15	Syndrome	Syndrome	NNP
cord-258708-da6x5rxa	165	16	Coronavirus	Coronavirus	NNP
cord-258708-da6x5rxa	165	17	2	2	CD
cord-258708-da6x5rxa	165	18	Infection	Infection	NNP
cord-258708-da6x5rxa	165	19	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	165	20	cytokine	cytokine	NN
cord-258708-da6x5rxa	165	21	storm	storm	NN
cord-258708-da6x5rxa	165	22	:	:	:
cord-258708-da6x5rxa	165	23	the	the	DT
cord-258708-da6x5rxa	165	24	interplay	interplay	NN
cord-258708-da6x5rxa	165	25	between	between	IN
cord-258708-da6x5rxa	165	26	inflammation	inflammation	NN
cord-258708-da6x5rxa	165	27	and	and	CC
cord-258708-da6x5rxa	165	28	coagulation	coagulation	NN
cord-258708-da6x5rxa	165	29	.	.	.
cord-258708-da6x5rxa	166	1	The	the	DT
cord-258708-da6x5rxa	166	2	Lancet	Lancet	NNP
cord-258708-da6x5rxa	166	3	Respiratory	respiratory	JJ
cord-258708-da6x5rxa	166	4	Medicine	medicine	NN
cord-258708-da6x5rxa	167	1	A	a	DT
cord-258708-da6x5rxa	167	2	pneumonia	pneumonia	NN
cord-258708-da6x5rxa	167	3	outbreak	outbreak	NN
cord-258708-da6x5rxa	167	4	associated	associate	VBN
cord-258708-da6x5rxa	167	5	with	with	IN
cord-258708-da6x5rxa	167	6	a	a	DT
cord-258708-da6x5rxa	167	7	new	new	JJ
cord-258708-da6x5rxa	167	8	coronavirus	coronavirus	NN
cord-258708-da6x5rxa	167	9	of	of	IN
cord-258708-da6x5rxa	167	10	probable	probable	JJ
cord-258708-da6x5rxa	167	11	bat	bat	NN
cord-258708-da6x5rxa	167	12	origin	origin	NN
cord-258708-da6x5rxa	167	13	A	a	DT
cord-258708-da6x5rxa	167	14	Novel	Novel	NNP
cord-258708-da6x5rxa	167	15	Coronavirus	Coronavirus	NNP
cord-258708-da6x5rxa	167	16	from	from	IN
cord-258708-da6x5rxa	167	17	Patients	patient	NNS
cord-258708-da6x5rxa	167	18	with	with	IN
cord-258708-da6x5rxa	167	19	Pneumonia	Pneumonia	NNP
cord-258708-da6x5rxa	167	20	in	in	IN
cord-258708-da6x5rxa	167	21	China	China	NNP
cord-258708-da6x5rxa	167	22	Genomic	Genomic	NNP
cord-258708-da6x5rxa	167	23	characterisation	characterisation	NN
cord-258708-da6x5rxa	167	24	and	and	CC
cord-258708-da6x5rxa	167	25	epidemiology	epidemiology	NN
cord-258708-da6x5rxa	167	26	of	of	IN
cord-258708-da6x5rxa	167	27	2019	2019	CD
cord-258708-da6x5rxa	167	28	novel	novel	JJ
cord-258708-da6x5rxa	167	29	coronavirus	coronavirus	NN
cord-258708-da6x5rxa	167	30	:	:	:
cord-258708-da6x5rxa	167	31	implications	implication	NNS
cord-258708-da6x5rxa	167	32	for	for	IN
cord-258708-da6x5rxa	167	33	virus	virus	NN
cord-258708-da6x5rxa	167	34	origins	origin	NNS
cord-258708-da6x5rxa	167	35	and	and	CC
cord-258708-da6x5rxa	167	36	receptor	receptor	NN
cord-258708-da6x5rxa	167	37	binding	bind	VBG
cord-258708-da6x5rxa	167	38	COVID-19	covid-19	CD
cord-258708-da6x5rxa	167	39	infection	infection	NN
cord-258708-da6x5rxa	167	40	:	:	:
cord-258708-da6x5rxa	167	41	Origin	origin	NN
cord-258708-da6x5rxa	167	42	,	,	,
cord-258708-da6x5rxa	167	43	transmission	transmission	NN
cord-258708-da6x5rxa	167	44	,	,	,
cord-258708-da6x5rxa	167	45	and	and	CC
cord-258708-da6x5rxa	167	46	characteristics	characteristic	NNS
cord-258708-da6x5rxa	167	47	of	of	IN
cord-258708-da6x5rxa	167	48	human	human	JJ
cord-258708-da6x5rxa	167	49	coronaviruses	coronaviruse	NNS
cord-258708-da6x5rxa	167	50	Cryo	Cryo	NNP
cord-258708-da6x5rxa	167	51	-	-	HYPH
cord-258708-da6x5rxa	167	52	EM	EM	NNP
cord-258708-da6x5rxa	167	53	structure	structure	NN
cord-258708-da6x5rxa	167	54	of	of	IN
cord-258708-da6x5rxa	167	55	the	the	DT
cord-258708-da6x5rxa	167	56	SARS	SARS	NNP
cord-258708-da6x5rxa	167	57	coronavirus	coronavirus	NN
cord-258708-da6x5rxa	167	58	spike	spike	NN
cord-258708-da6x5rxa	167	59	glycoprotein	glycoprotein	NN
cord-258708-da6x5rxa	167	60	in	in	IN
cord-258708-da6x5rxa	167	61	complex	complex	NN
cord-258708-da6x5rxa	167	62	with	with	IN
cord-258708-da6x5rxa	167	63	its	-PRON-	PRP$
cord-258708-da6x5rxa	167	64	host	host	NN
cord-258708-da6x5rxa	167	65	cell	cell	NN
cord-258708-da6x5rxa	167	66	receptor	receptor	NN
cord-258708-da6x5rxa	167	67	ACE2	ACE2	NNP
cord-258708-da6x5rxa	167	68	Cryo	Cryo	NNP
cord-258708-da6x5rxa	167	69	-	-	HYPH
cord-258708-da6x5rxa	167	70	EM	EM	NNP
cord-258708-da6x5rxa	167	71	structure	structure	NN
cord-258708-da6x5rxa	167	72	of	of	IN
cord-258708-da6x5rxa	167	73	the	the	DT
cord-258708-da6x5rxa	167	74	2019-nCoV	2019-ncov	CD
cord-258708-da6x5rxa	167	75	spike	spike	NN
cord-258708-da6x5rxa	167	76	in	in	IN
cord-258708-da6x5rxa	167	77	the	the	DT
cord-258708-da6x5rxa	167	78	prefusion	prefusion	NN
cord-258708-da6x5rxa	167	79	conformation	conformation	NN
cord-258708-da6x5rxa	167	80	Structural	structural	JJ
cord-258708-da6x5rxa	167	81	basis	basis	NN
cord-258708-da6x5rxa	167	82	for	for	IN
cord-258708-da6x5rxa	167	83	the	the	DT
cord-258708-da6x5rxa	167	84	recognition	recognition	NN
cord-258708-da6x5rxa	167	85	of	of	IN
cord-258708-da6x5rxa	167	86	SARS	SARS	NNP
cord-258708-da6x5rxa	167	87	-	-	HYPH
cord-258708-da6x5rxa	167	88	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	167	89	by	by	IN
cord-258708-da6x5rxa	167	90	full	full	JJ
cord-258708-da6x5rxa	167	91	-	-	HYPH
cord-258708-da6x5rxa	167	92	length	length	NN
cord-258708-da6x5rxa	167	93	human	human	JJ
cord-258708-da6x5rxa	167	94	ACE2	ace2	NN
cord-258708-da6x5rxa	168	1	The	the	DT
cord-258708-da6x5rxa	168	2	Science	Science	NNP
cord-258708-da6x5rxa	168	3	Underlying	underlying	NN
cord-258708-da6x5rxa	169	1	COVID-19	covid-19	VB
cord-258708-da6x5rxa	169	2	:	:	:
cord-258708-da6x5rxa	169	3	Implications	implication	NNS
cord-258708-da6x5rxa	169	4	for	for	IN
cord-258708-da6x5rxa	169	5	the	the	DT
cord-258708-da6x5rxa	169	6	Cardiovascular	Cardiovascular	NNP
cord-258708-da6x5rxa	169	7	System	System	NNP
cord-258708-da6x5rxa	170	1	The	the	DT
cord-258708-da6x5rxa	170	2	spike	spike	NN
cord-258708-da6x5rxa	170	3	glycoprotein	glycoprotein	NN
cord-258708-da6x5rxa	170	4	of	of	IN
cord-258708-da6x5rxa	170	5	the	the	DT
cord-258708-da6x5rxa	170	6	new	new	JJ
cord-258708-da6x5rxa	170	7	coronavirus	coronavirus	NN
cord-258708-da6x5rxa	170	8	2019-nCoV	2019-ncov	CD
cord-258708-da6x5rxa	170	9	contains	contain	VBZ
cord-258708-da6x5rxa	170	10	a	a	DT
cord-258708-da6x5rxa	170	11	furin	furin	NN
cord-258708-da6x5rxa	170	12	-	-	HYPH
cord-258708-da6x5rxa	170	13	like	like	JJ
cord-258708-da6x5rxa	170	14	cleavage	cleavage	NN
cord-258708-da6x5rxa	170	15	site	site	NN
cord-258708-da6x5rxa	170	16	absent	absent	JJ
cord-258708-da6x5rxa	170	17	in	in	IN
cord-258708-da6x5rxa	170	18	CoV	cov	NN
cord-258708-da6x5rxa	170	19	of	of	IN
cord-258708-da6x5rxa	170	20	the	the	DT
cord-258708-da6x5rxa	170	21	same	same	JJ
cord-258708-da6x5rxa	170	22	clade	clade	NN
cord-258708-da6x5rxa	170	23	ACE2	ACE2	NNP
cord-258708-da6x5rxa	170	24	of	of	IN
cord-258708-da6x5rxa	170	25	the	the	DT
cord-258708-da6x5rxa	170	26	heart	heart	NN
cord-258708-da6x5rxa	170	27	:	:	:
cord-258708-da6x5rxa	171	1	From	from	IN
cord-258708-da6x5rxa	171	2	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	171	3	I	-PRON-	PRP
cord-258708-da6x5rxa	171	4	to	to	IN
cord-258708-da6x5rxa	171	5	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	172	1	Emerging	emerge	VBG
cord-258708-da6x5rxa	172	2	COVID-19	covid-19	JJ
cord-258708-da6x5rxa	172	3	coronavirus	coronavirus	NN
cord-258708-da6x5rxa	172	4	:	:	:
cord-258708-da6x5rxa	173	1	glycan	glycan	NNP
cord-258708-da6x5rxa	173	2	shield	shield	NNP
cord-258708-da6x5rxa	173	3	and	and	CC
cord-258708-da6x5rxa	173	4	structure	structure	NN
cord-258708-da6x5rxa	173	5	prediction	prediction	NN
cord-258708-da6x5rxa	173	6	of	of	IN
cord-258708-da6x5rxa	173	7	spike	spike	NN
cord-258708-da6x5rxa	173	8	glycoprotein	glycoprotein	NN
cord-258708-da6x5rxa	173	9	and	and	CC
cord-258708-da6x5rxa	173	10	its	-PRON-	PRP$
cord-258708-da6x5rxa	173	11	interaction	interaction	NN
cord-258708-da6x5rxa	173	12	with	with	IN
cord-258708-da6x5rxa	173	13	human	human	JJ
cord-258708-da6x5rxa	173	14	CD26	CD26	NNP
cord-258708-da6x5rxa	173	15	Coronavirus	Coronavirus	NNP
cord-258708-da6x5rxa	173	16	Disease	Disease	NNP
cord-258708-da6x5rxa	173	17	2019	2019	CD
cord-258708-da6x5rxa	173	18	(	(	-LRB-
cord-258708-da6x5rxa	173	19	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	173	20	)	)	-RRB-
cord-258708-da6x5rxa	173	21	Infection	Infection	NNP
cord-258708-da6x5rxa	173	22	and	and	CC
cord-258708-da6x5rxa	173	23	Renin	Renin	NNP
cord-258708-da6x5rxa	173	24	Angiotensin	Angiotensin	NNP
cord-258708-da6x5rxa	173	25	System	System	NNP
cord-258708-da6x5rxa	173	26	Blockers	Blockers	NNP
cord-258708-da6x5rxa	173	27	Cardiac	Cardiac	NNP
cord-258708-da6x5rxa	173	28	Involvement	Involvement	NNP
cord-258708-da6x5rxa	173	29	in	in	IN
cord-258708-da6x5rxa	173	30	a	a	DT
cord-258708-da6x5rxa	173	31	Patient	patient	NN
cord-258708-da6x5rxa	173	32	With	with	IN
cord-258708-da6x5rxa	173	33	Coronavirus	Coronavirus	NNP
cord-258708-da6x5rxa	173	34	Disease	Disease	NNP
cord-258708-da6x5rxa	173	35	2019	2019	CD
cord-258708-da6x5rxa	173	36	(	(	-LRB-
cord-258708-da6x5rxa	173	37	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	173	38	)	)	-RRB-
cord-258708-da6x5rxa	173	39	Clinical	Clinical	NNP
cord-258708-da6x5rxa	173	40	Characteristics	characteristic	NNS
cord-258708-da6x5rxa	173	41	of	of	IN
cord-258708-da6x5rxa	173	42	138	138	CD
cord-258708-da6x5rxa	173	43	Hospitalized	hospitalize	VBN
cord-258708-da6x5rxa	173	44	Patients	patient	NNS
cord-258708-da6x5rxa	173	45	With	with	IN
cord-258708-da6x5rxa	174	1	2019	2019	CD
cord-258708-da6x5rxa	174	2	Novel	Novel	NNP
cord-258708-da6x5rxa	174	3	Coronavirus	Coronavirus	NNP
cord-258708-da6x5rxa	174	4	-	-	HYPH
cord-258708-da6x5rxa	174	5	Infected	infect	VBN
cord-258708-da6x5rxa	174	6	Pneumonia	Pneumonia	NNP
cord-258708-da6x5rxa	174	7	in	in	IN
cord-258708-da6x5rxa	174	8	Wuhan	Wuhan	NNP
cord-258708-da6x5rxa	174	9	SARS	SARS	NNP
cord-258708-da6x5rxa	174	10	-	-	HYPH
cord-258708-da6x5rxa	174	11	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	174	12	infects	infect	VBZ
cord-258708-da6x5rxa	174	13	and	and	CC
cord-258708-da6x5rxa	174	14	induces	induce	VBZ
cord-258708-da6x5rxa	174	15	cytotoxic	cytotoxic	JJ
cord-258708-da6x5rxa	174	16	effects	effect	NNS
cord-258708-da6x5rxa	174	17	in	in	IN
cord-258708-da6x5rxa	174	18	human	human	JJ
cord-258708-da6x5rxa	174	19	cardiomyocytes	cardiomyocyte	NNS
cord-258708-da6x5rxa	175	1	The	the	DT
cord-258708-da6x5rxa	175	2	Science	Science	NNP
cord-258708-da6x5rxa	175	3	Underlying	underlying	NN
cord-258708-da6x5rxa	176	1	COVID-19	covid-19	VB
cord-258708-da6x5rxa	176	2	:	:	:
cord-258708-da6x5rxa	176	3	Implications	implication	NNS
cord-258708-da6x5rxa	176	4	for	for	IN
cord-258708-da6x5rxa	176	5	the	the	DT
cord-258708-da6x5rxa	176	6	Cardiovascular	Cardiovascular	NNP
cord-258708-da6x5rxa	176	7	System	System	NNP
cord-258708-da6x5rxa	176	8	Clinical	clinical	JJ
cord-258708-da6x5rxa	176	9	features	feature	NNS
cord-258708-da6x5rxa	176	10	of	of	IN
cord-258708-da6x5rxa	176	11	patients	patient	NNS
cord-258708-da6x5rxa	176	12	infected	infect	VBN
cord-258708-da6x5rxa	176	13	with	with	IN
cord-258708-da6x5rxa	176	14	2019	2019	CD
cord-258708-da6x5rxa	176	15	novel	novel	JJ
cord-258708-da6x5rxa	176	16	coronavirus	coronavirus	NN
cord-258708-da6x5rxa	176	17	in	in	IN
cord-258708-da6x5rxa	176	18	Wuhan	Wuhan	NNP
cord-258708-da6x5rxa	176	19	Clinical	Clinical	NNP
cord-258708-da6x5rxa	176	20	Characteristics	Characteristics	NNPS
cord-258708-da6x5rxa	176	21	of	of	IN
cord-258708-da6x5rxa	176	22	Coronavirus	Coronavirus	NNP
cord-258708-da6x5rxa	176	23	Disease	Disease	NNP
cord-258708-da6x5rxa	176	24	2019	2019	CD
cord-258708-da6x5rxa	176	25	in	in	IN
cord-258708-da6x5rxa	176	26	China	China	NNP
cord-258708-da6x5rxa	177	1	Angiotensin	angiotensin	NN
cord-258708-da6x5rxa	177	2	-	-	HYPH
cord-258708-da6x5rxa	177	3	converting	convert	VBG
cord-258708-da6x5rxa	177	4	enzyme	enzyme	NN
cord-258708-da6x5rxa	177	5	2	2	CD
cord-258708-da6x5rxa	177	6	in	in	IN
cord-258708-da6x5rxa	177	7	severe	severe	JJ
cord-258708-da6x5rxa	177	8	acute	acute	JJ
cord-258708-da6x5rxa	177	9	respiratory	respiratory	JJ
cord-258708-da6x5rxa	177	10	syndrome	syndrome	NN
cord-258708-da6x5rxa	177	11	coronavirus	coronavirus	NN
cord-258708-da6x5rxa	177	12	and	and	CC
cord-258708-da6x5rxa	177	13	SARS	SARS	NNP
cord-258708-da6x5rxa	177	14	-	-	HYPH
cord-258708-da6x5rxa	177	15	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	177	16	:	:	:
cord-258708-da6x5rxa	178	1	A	a	DT
cord-258708-da6x5rxa	178	2	double	double	RB
cord-258708-da6x5rxa	178	3	-	-	HYPH
cord-258708-da6x5rxa	178	4	edged	edged	JJ
cord-258708-da6x5rxa	178	5	sword	sword	NN
cord-258708-da6x5rxa	178	6	?	?	.
cord-258708-da6x5rxa	179	1	Angiotensin	angiotensin	NN
cord-258708-da6x5rxa	179	2	-	-	HYPH
cord-258708-da6x5rxa	179	3	converting	convert	VBG
cord-258708-da6x5rxa	179	4	enzyme	enzyme	NN
cord-258708-da6x5rxa	179	5	2	2	CD
cord-258708-da6x5rxa	179	6	is	be	VBZ
cord-258708-da6x5rxa	179	7	an	an	DT
cord-258708-da6x5rxa	179	8	essential	essential	JJ
cord-258708-da6x5rxa	179	9	regulator	regulator	NN
cord-258708-da6x5rxa	179	10	of	of	IN
cord-258708-da6x5rxa	179	11	heart	heart	NN
cord-258708-da6x5rxa	179	12	function	function	NN
cord-258708-da6x5rxa	179	13	Characterization	characterization	NN
cord-258708-da6x5rxa	179	14	of	of	IN
cord-258708-da6x5rxa	179	15	ACE	ACE	NNP
cord-258708-da6x5rxa	179	16	and	and	CC
cord-258708-da6x5rxa	179	17	ACE2	ACE2	NNP
cord-258708-da6x5rxa	179	18	Expression	expression	NN
cord-258708-da6x5rxa	179	19	within	within	IN
cord-258708-da6x5rxa	179	20	Different	different	JJ
cord-258708-da6x5rxa	179	21	Organs	organ	NNS
cord-258708-da6x5rxa	179	22	of	of	IN
cord-258708-da6x5rxa	179	23	the	the	DT
cord-258708-da6x5rxa	179	24	NOD	NOD	NNP
cord-258708-da6x5rxa	179	25	Mouse	Mouse	NNP
cord-258708-da6x5rxa	179	26	.	.	.
cord-258708-da6x5rxa	180	1	International	international	JJ
cord-258708-da6x5rxa	180	2	journal	journal	NN
cord-258708-da6x5rxa	180	3	of	of	IN
cord-258708-da6x5rxa	180	4	molecular	molecular	NNP
cord-258708-da6x5rxa	180	5	sciences	sciences	NNPS
cord-258708-da6x5rxa	180	6	A	a	DT
cord-258708-da6x5rxa	180	7	crucial	crucial	JJ
cord-258708-da6x5rxa	180	8	role	role	NN
cord-258708-da6x5rxa	180	9	of	of	IN
cord-258708-da6x5rxa	180	10	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	180	11	converting	convert	VBG
cord-258708-da6x5rxa	180	12	enzyme	enzyme	NN
cord-258708-da6x5rxa	180	13	2	2	CD
cord-258708-da6x5rxa	180	14	(	(	-LRB-
cord-258708-da6x5rxa	180	15	ACE2	ACE2	NNP
cord-258708-da6x5rxa	180	16	)	)	-RRB-
cord-258708-da6x5rxa	180	17	in	in	IN
cord-258708-da6x5rxa	180	18	SARS	SARS	NNP
cord-258708-da6x5rxa	180	19	coronavirus	coronavirus	NN
cord-258708-da6x5rxa	180	20	-	-	HYPH
cord-258708-da6x5rxa	180	21	induced	induce	VBN
cord-258708-da6x5rxa	180	22	lung	lung	NN
cord-258708-da6x5rxa	180	23	injury	injury	NN
cord-258708-da6x5rxa	180	24	19	19	CD
cord-258708-da6x5rxa	180	25	)	)	-RRB-
cord-258708-da6x5rxa	180	26	and	and	CC
cord-258708-da6x5rxa	180	27	Cardiovascular	Cardiovascular	NNP
cord-258708-da6x5rxa	180	28	Disease	Disease	NNP
cord-258708-da6x5rxa	180	29	:	:	:
cord-258708-da6x5rxa	181	1	A	a	DT
cord-258708-da6x5rxa	181	2	Viewpoint	viewpoint	NN
cord-258708-da6x5rxa	181	3	on	on	IN
cord-258708-da6x5rxa	181	4	the	the	DT
cord-258708-da6x5rxa	181	5	Potential	potential	JJ
cord-258708-da6x5rxa	181	6	Influence	influence	NN
cord-258708-da6x5rxa	181	7	of	of	IN
cord-258708-da6x5rxa	181	8	Angiotensin‐Converting	angiotensin‐converte	VBG
cord-258708-da6x5rxa	181	9	Enzyme	Enzyme	NNP
cord-258708-da6x5rxa	181	10	Inhibitors	Inhibitors	NNP
cord-258708-da6x5rxa	181	11	/	/	SYM
cord-258708-da6x5rxa	181	12	Angiotensin	Angiotensin	NNP
cord-258708-da6x5rxa	181	13	Receptor	Receptor	NNP
cord-258708-da6x5rxa	181	14	Blockers	Blockers	NNP
cord-258708-da6x5rxa	181	15	on	on	IN
cord-258708-da6x5rxa	181	16	Onset	Onset	NNP
cord-258708-da6x5rxa	181	17	and	and	CC
cord-258708-da6x5rxa	181	18	Severity	severity	NN
cord-258708-da6x5rxa	181	19	of	of	IN
cord-258708-da6x5rxa	181	20	Severe	severe	JJ
cord-258708-da6x5rxa	181	21	Acute	acute	JJ
cord-258708-da6x5rxa	181	22	Respiratory	Respiratory	NNP
cord-258708-da6x5rxa	181	23	Syndrome	Syndrome	NNP
cord-258708-da6x5rxa	181	24	Coronavirus	Coronavirus	NNP
cord-258708-da6x5rxa	181	25	2	2	CD
cord-258708-da6x5rxa	181	26	Infection	Infection	NNP
cord-258708-da6x5rxa	181	27	Cardiovascular	Cardiovascular	NNP
cord-258708-da6x5rxa	181	28	disease	disease	NN
cord-258708-da6x5rxa	181	29	and	and	CC
cord-258708-da6x5rxa	181	30	COVID-19	covid-19	NN
cord-258708-da6x5rxa	181	31	.	.	.
cord-258708-da6x5rxa	182	1	Diabetes	diabetes	NN
cord-258708-da6x5rxa	182	2	&	&	CC
cord-258708-da6x5rxa	182	3	metabolic	metabolic	JJ
cord-258708-da6x5rxa	182	4	syndrome	syndrome	NN
cord-258708-da6x5rxa	182	5	Coronavirus	Coronavirus	NNP
cord-258708-da6x5rxa	182	6	fulminant	fulminant	JJ
cord-258708-da6x5rxa	182	7	myocarditis	myocarditis	NN
cord-258708-da6x5rxa	182	8	treated	treat	VBN
cord-258708-da6x5rxa	182	9	with	with	IN
cord-258708-da6x5rxa	182	10	glucocorticoid	glucocorticoid	NN
cord-258708-da6x5rxa	182	11	and	and	CC
cord-258708-da6x5rxa	182	12	human	human	JJ
cord-258708-da6x5rxa	182	13	immunoglobulin	immunoglobulin	NN
cord-258708-da6x5rxa	182	14	Renin	renin	NN
cord-258708-da6x5rxa	182	15	-	-	HYPH
cord-258708-da6x5rxa	182	16	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	182	17	-	-	HYPH
cord-258708-da6x5rxa	182	18	aldosterone	aldosterone	NN
cord-258708-da6x5rxa	182	19	system	system	NN
cord-258708-da6x5rxa	182	20	inhibitors	inhibitor	NNS
cord-258708-da6x5rxa	182	21	and	and	CC
cord-258708-da6x5rxa	182	22	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	182	23	A	a	DT
cord-258708-da6x5rxa	182	24	pilot	pilot	NN
cord-258708-da6x5rxa	182	25	clinical	clinical	JJ
cord-258708-da6x5rxa	182	26	trial	trial	NN
cord-258708-da6x5rxa	182	27	of	of	IN
cord-258708-da6x5rxa	182	28	recombinant	recombinant	JJ
cord-258708-da6x5rxa	182	29	human	human	JJ
cord-258708-da6x5rxa	182	30	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	182	31	-	-	HYPH
cord-258708-da6x5rxa	182	32	converting	convert	VBG
cord-258708-da6x5rxa	182	33	enzyme	enzyme	NN
cord-258708-da6x5rxa	182	34	2	2	CD
cord-258708-da6x5rxa	182	35	in	in	IN
cord-258708-da6x5rxa	182	36	acute	acute	JJ
cord-258708-da6x5rxa	182	37	respiratory	respiratory	JJ
cord-258708-da6x5rxa	182	38	distress	distress	NN
cord-258708-da6x5rxa	182	39	syndrome	syndrome	NN
cord-258708-da6x5rxa	182	40	Coronavirus	Coronavirus	NNP
cord-258708-da6x5rxa	182	41	Disease	Disease	NNP
cord-258708-da6x5rxa	182	42	2019	2019	CD
cord-258708-da6x5rxa	182	43	and	and	CC
cord-258708-da6x5rxa	182	44	Stroke	stroke	NN
cord-258708-da6x5rxa	182	45	:	:	:
cord-258708-da6x5rxa	183	1	Clinical	clinical	JJ
cord-258708-da6x5rxa	183	2	Manifestations	Manifestations	NNPS
cord-258708-da6x5rxa	183	3	and	and	CC
cord-258708-da6x5rxa	183	4	Pathophysiological	Pathophysiological	NNP
cord-258708-da6x5rxa	183	5	Insights	Insights	NNPS
cord-258708-da6x5rxa	183	6	Susceptibility	Susceptibility	NNP
cord-258708-da6x5rxa	183	7	to	to	IN
cord-258708-da6x5rxa	183	8	SARS	SARS	NNP
cord-258708-da6x5rxa	183	9	coronavirus	coronavirus	NN
cord-258708-da6x5rxa	183	10	S	S	NNP
cord-258708-da6x5rxa	183	11	protein	protein	NN
cord-258708-da6x5rxa	183	12	-	-	HYPH
cord-258708-da6x5rxa	183	13	driven	drive	VBN
cord-258708-da6x5rxa	183	14	infection	infection	NN
cord-258708-da6x5rxa	183	15	correlates	correlate	VBZ
cord-258708-da6x5rxa	183	16	with	with	IN
cord-258708-da6x5rxa	183	17	expression	expression	NN
cord-258708-da6x5rxa	183	18	of	of	IN
cord-258708-da6x5rxa	183	19	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	183	20	converting	convert	VBG
cord-258708-da6x5rxa	183	21	enzyme	enzyme	NN
cord-258708-da6x5rxa	183	22	2	2	CD
cord-258708-da6x5rxa	183	23	and	and	CC
cord-258708-da6x5rxa	183	24	infection	infection	NN
cord-258708-da6x5rxa	183	25	can	can	MD
cord-258708-da6x5rxa	183	26	be	be	VB
cord-258708-da6x5rxa	183	27	blocked	block	VBN
cord-258708-da6x5rxa	183	28	by	by	IN
cord-258708-da6x5rxa	183	29	soluble	soluble	JJ
cord-258708-da6x5rxa	183	30	receptor	receptor	NN
cord-258708-da6x5rxa	183	31	.	.	.
cord-258708-da6x5rxa	184	1	Biochemical	biochemical	JJ
cord-258708-da6x5rxa	184	2	and	and	CC
cord-258708-da6x5rxa	184	3	biophysical	biophysical	JJ
cord-258708-da6x5rxa	184	4	research	research	NN
cord-258708-da6x5rxa	184	5	communications	communication	NNS
cord-258708-da6x5rxa	185	1	A	a	DT
cord-258708-da6x5rxa	185	2	potential	potential	JJ
cord-258708-da6x5rxa	185	3	therapeutic	therapeutic	JJ
cord-258708-da6x5rxa	185	4	role	role	NN
cord-258708-da6x5rxa	185	5	for	for	IN
cord-258708-da6x5rxa	185	6	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	185	7	-	-	HYPH
cord-258708-da6x5rxa	185	8	converting	convert	VBG
cord-258708-da6x5rxa	185	9	enzyme	enzyme	NN
cord-258708-da6x5rxa	185	10	2	2	CD
cord-258708-da6x5rxa	185	11	in	in	IN
cord-258708-da6x5rxa	185	12	human	human	JJ
cord-258708-da6x5rxa	185	13	pulmonary	pulmonary	JJ
cord-258708-da6x5rxa	185	14	arterial	arterial	JJ
cord-258708-da6x5rxa	185	15	hypertension	hypertension	NN
cord-258708-da6x5rxa	185	16	.	.	.
cord-258708-da6x5rxa	186	1	The	the	DT
cord-258708-da6x5rxa	186	2	European	european	JJ
cord-258708-da6x5rxa	186	3	respiratory	respiratory	JJ
cord-258708-da6x5rxa	186	4	journal	journal	NN
cord-258708-da6x5rxa	186	5	Use	use	NN
cord-258708-da6x5rxa	186	6	of	of	IN
cord-258708-da6x5rxa	186	7	renin	renin	NN
cord-258708-da6x5rxa	186	8	-	-	HYPH
cord-258708-da6x5rxa	186	9	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	186	10	-	-	HYPH
cord-258708-da6x5rxa	186	11	aldosterone	aldosterone	NN
cord-258708-da6x5rxa	186	12	system	system	NN
cord-258708-da6x5rxa	186	13	inhibitors	inhibitor	NNS
cord-258708-da6x5rxa	186	14	and	and	CC
cord-258708-da6x5rxa	186	15	risk	risk	NN
cord-258708-da6x5rxa	186	16	of	of	IN
cord-258708-da6x5rxa	186	17	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	186	18	requiring	require	VBG
cord-258708-da6x5rxa	186	19	admission	admission	NN
cord-258708-da6x5rxa	186	20	to	to	IN
cord-258708-da6x5rxa	186	21	hospital	hospital	NN
cord-258708-da6x5rxa	186	22	:	:	:
cord-258708-da6x5rxa	186	23	a	a	DT
cord-258708-da6x5rxa	186	24	case	case	NN
cord-258708-da6x5rxa	186	25	-	-	HYPH
cord-258708-da6x5rxa	186	26	population	population	NN
cord-258708-da6x5rxa	186	27	study	study	NN
cord-258708-da6x5rxa	186	28	Renin	Renin	NNP
cord-258708-da6x5rxa	186	29	-	-	HYPH
cord-258708-da6x5rxa	186	30	Angiotensin	Angiotensin	NNP
cord-258708-da6x5rxa	186	31	-	-	HYPH
cord-258708-da6x5rxa	186	32	Aldosterone	Aldosterone	NNP
cord-258708-da6x5rxa	186	33	System	System	NNP
cord-258708-da6x5rxa	186	34	Inhibitors	Inhibitors	NNP
cord-258708-da6x5rxa	186	35	and	and	CC
cord-258708-da6x5rxa	186	36	Risk	Risk	NNP
cord-258708-da6x5rxa	186	37	of	of	IN
cord-258708-da6x5rxa	186	38	Covid-19	Covid-19	NNP
cord-258708-da6x5rxa	186	39	.	.	.
cord-258708-da6x5rxa	187	1	The	the	DT
cord-258708-da6x5rxa	187	2	New	New	NNP
cord-258708-da6x5rxa	187	3	England	England	NNP
cord-258708-da6x5rxa	187	4	journal	journal	NN
cord-258708-da6x5rxa	187	5	of	of	IN
cord-258708-da6x5rxa	187	6	medicine	medicine	NNP
cord-258708-da6x5rxa	187	7	Renin	Renin	NNP
cord-258708-da6x5rxa	187	8	-	-	HYPH
cord-258708-da6x5rxa	187	9	Angiotensin	Angiotensin	NNP
cord-258708-da6x5rxa	187	10	-	-	HYPH
cord-258708-da6x5rxa	187	11	Aldosterone	Aldosterone	NNP
cord-258708-da6x5rxa	187	12	System	System	NNP
cord-258708-da6x5rxa	187	13	Inhibitors	Inhibitors	NNP
cord-258708-da6x5rxa	187	14	in	in	IN
cord-258708-da6x5rxa	187	15	Patients	patient	NNS
cord-258708-da6x5rxa	187	16	with	with	IN
cord-258708-da6x5rxa	187	17	Covid-19	Covid-19	NNP
cord-258708-da6x5rxa	187	18	Pathological	pathological	JJ
cord-258708-da6x5rxa	187	19	findings	finding	NNS
cord-258708-da6x5rxa	187	20	of	of	IN
cord-258708-da6x5rxa	187	21	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	187	22	associated	associate	VBN
cord-258708-da6x5rxa	187	23	with	with	IN
cord-258708-da6x5rxa	187	24	acute	acute	JJ
cord-258708-da6x5rxa	187	25	respiratory	respiratory	JJ
cord-258708-da6x5rxa	187	26	distress	distress	NN
cord-258708-da6x5rxa	187	27	syndrome	syndrome	NN
cord-258708-da6x5rxa	187	28	.	.	.
cord-258708-da6x5rxa	188	1	The	the	DT
cord-258708-da6x5rxa	188	2	Lancet	Lancet	NNP
cord-258708-da6x5rxa	188	3	Respiratory	respiratory	JJ
cord-258708-da6x5rxa	188	4	medicine	medicine	NN
cord-258708-da6x5rxa	188	5	Cardioimmunology	Cardioimmunology	NNP
cord-258708-da6x5rxa	188	6	of	of	IN
cord-258708-da6x5rxa	188	7	arrhythmias	arrhythmias	RB
cord-258708-da6x5rxa	188	8	:	:	:
cord-258708-da6x5rxa	188	9	the	the	DT
cord-258708-da6x5rxa	188	10	role	role	NN
cord-258708-da6x5rxa	188	11	of	of	IN
cord-258708-da6x5rxa	188	12	autoimmune	autoimmune	JJ
cord-258708-da6x5rxa	188	13	and	and	CC
cord-258708-da6x5rxa	188	14	inflammatory	inflammatory	JJ
cord-258708-da6x5rxa	188	15	cardiac	cardiac	JJ
cord-258708-da6x5rxa	188	16	channelopathies	channelopathie	NNS
cord-258708-da6x5rxa	188	17	Coronavirus	Coronavirus	NNP
cord-258708-da6x5rxa	188	18	fulminant	fulminant	JJ
cord-258708-da6x5rxa	188	19	myocarditis	myocarditis	NN
cord-258708-da6x5rxa	188	20	saved	save	VBN
cord-258708-da6x5rxa	188	21	with	with	IN
cord-258708-da6x5rxa	188	22	glucocorticoid	glucocorticoid	NN
cord-258708-da6x5rxa	188	23	and	and	CC
cord-258708-da6x5rxa	188	24	human	human	JJ
cord-258708-da6x5rxa	188	25	immunoglobulin	immunoglobulin	NN
cord-258708-da6x5rxa	188	26	Cardiovascular	Cardiovascular	NNP
cord-258708-da6x5rxa	188	27	Considerations	Considerations	NNPS
cord-258708-da6x5rxa	188	28	for	for	IN
cord-258708-da6x5rxa	188	29	Patients	patient	NNS
cord-258708-da6x5rxa	188	30	,	,	,
cord-258708-da6x5rxa	188	31	Health	Health	NNP
cord-258708-da6x5rxa	188	32	Care	Care	NNP
cord-258708-da6x5rxa	188	33	Workers	Workers	NNPS
cord-258708-da6x5rxa	188	34	,	,	,
cord-258708-da6x5rxa	188	35	and	and	CC
cord-258708-da6x5rxa	188	36	Health	Health	NNP
cord-258708-da6x5rxa	188	37	Systems	Systems	NNPS
cord-258708-da6x5rxa	188	38	During	during	IN
cord-258708-da6x5rxa	188	39	the	the	DT
cord-258708-da6x5rxa	188	40	Coronavirus	Coronavirus	NNP
cord-258708-da6x5rxa	188	41	Disease	Disease	NNP
cord-258708-da6x5rxa	188	42	2019	2019	CD
cord-258708-da6x5rxa	188	43	(	(	-LRB-
cord-258708-da6x5rxa	188	44	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	188	45	)	)	-RRB-
cord-258708-da6x5rxa	188	46	Pandemic	Pandemic	NNP
cord-258708-da6x5rxa	188	47	Cardiovascular	Cardiovascular	NNP
cord-258708-da6x5rxa	188	48	Implications	implication	NNS
cord-258708-da6x5rxa	188	49	of	of	IN
cord-258708-da6x5rxa	188	50	Fatal	fatal	JJ
cord-258708-da6x5rxa	188	51	Outcomes	Outcomes	NNPS
cord-258708-da6x5rxa	188	52	of	of	IN
cord-258708-da6x5rxa	188	53	Patients	patient	NNS
cord-258708-da6x5rxa	188	54	With	with	IN
cord-258708-da6x5rxa	188	55	Coronavirus	Coronavirus	NNP
cord-258708-da6x5rxa	188	56	Disease	Disease	NNP
cord-258708-da6x5rxa	188	57	2019	2019	CD
cord-258708-da6x5rxa	188	58	(	(	-LRB-
cord-258708-da6x5rxa	188	59	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	188	60	)	)	-RRB-
cord-258708-da6x5rxa	188	61	Clinical	clinical	JJ
cord-258708-da6x5rxa	188	62	course	course	NN
cord-258708-da6x5rxa	188	63	and	and	CC
cord-258708-da6x5rxa	188	64	risk	risk	NN
cord-258708-da6x5rxa	188	65	factors	factor	NNS
cord-258708-da6x5rxa	188	66	for	for	IN
cord-258708-da6x5rxa	188	67	mortality	mortality	NN
cord-258708-da6x5rxa	188	68	of	of	IN
cord-258708-da6x5rxa	188	69	adult	adult	NN
cord-258708-da6x5rxa	188	70	inpatients	inpatient	NNS
cord-258708-da6x5rxa	188	71	with	with	IN
cord-258708-da6x5rxa	188	72	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	188	73	in	in	IN
cord-258708-da6x5rxa	188	74	Wuhan	Wuhan	NNP
cord-258708-da6x5rxa	188	75	,	,	,
cord-258708-da6x5rxa	188	76	China	China	NNP
cord-258708-da6x5rxa	188	77	:	:	:
cord-258708-da6x5rxa	188	78	a	a	DT
cord-258708-da6x5rxa	188	79	retrospective	retrospective	JJ
cord-258708-da6x5rxa	188	80	cohort	cohort	NN
cord-258708-da6x5rxa	188	81	study	study	NN
cord-258708-da6x5rxa	188	82	Elevated	Elevated	NNP
cord-258708-da6x5rxa	188	83	Troponin	Troponin	NNP
cord-258708-da6x5rxa	188	84	in	in	IN
cord-258708-da6x5rxa	188	85	Patients	patient	NNS
cord-258708-da6x5rxa	188	86	With	with	IN
cord-258708-da6x5rxa	188	87	Coronavirus	Coronavirus	NNP
cord-258708-da6x5rxa	188	88	Disease	Disease	NNP
cord-258708-da6x5rxa	188	89	2019	2019	CD
cord-258708-da6x5rxa	188	90	:	:	:
cord-258708-da6x5rxa	189	1	Possible	possible	JJ
cord-258708-da6x5rxa	189	2	Mechanisms	Mechanisms	NNPS
cord-258708-da6x5rxa	189	3	Troponin	Troponin	NNP
cord-258708-da6x5rxa	189	4	and	and	CC
cord-258708-da6x5rxa	189	5	BNP	BNP	NNP
cord-258708-da6x5rxa	189	6	Use	Use	NNP
cord-258708-da6x5rxa	189	7	in	in	IN
cord-258708-da6x5rxa	189	8	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	189	9	.	.	.
cord-258708-da6x5rxa	190	1	American	American	NNP
cord-258708-da6x5rxa	190	2	College	College	NNP
cord-258708-da6x5rxa	190	3	of	of	IN
cord-258708-da6x5rxa	190	4	Cardiology	Cardiology	NNP
cord-258708-da6x5rxa	190	5	High	High	NNP
cord-258708-da6x5rxa	190	6	-	-	HYPH
cord-258708-da6x5rxa	190	7	Sensitivity	Sensitivity	NNP
cord-258708-da6x5rxa	190	8	Cardiac	Cardiac	NNP
cord-258708-da6x5rxa	190	9	Troponin	Troponin	NNP
cord-258708-da6x5rxa	190	10	Can	Can	MD
cord-258708-da6x5rxa	190	11	Be	be	VB
cord-258708-da6x5rxa	190	12	an	an	DT
cord-258708-da6x5rxa	190	13	Ally	Ally	NNP
cord-258708-da6x5rxa	190	14	in	in	IN
cord-258708-da6x5rxa	190	15	the	the	DT
cord-258708-da6x5rxa	190	16	Fight	Fight	NNP
cord-258708-da6x5rxa	190	17	Against	against	IN
cord-258708-da6x5rxa	190	18	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	190	19	Cardiac	Cardiac	NNP
cord-258708-da6x5rxa	190	20	biomarker	biomarker	NN
cord-258708-da6x5rxa	190	21	-	-	HYPH
cord-258708-da6x5rxa	190	22	based	base	VBN
cord-258708-da6x5rxa	190	23	risk	risk	NN
cord-258708-da6x5rxa	190	24	stratification	stratification	NN
cord-258708-da6x5rxa	190	25	algorithm	algorithm	NN
cord-258708-da6x5rxa	190	26	in	in	IN
cord-258708-da6x5rxa	190	27	patients	patient	NNS
cord-258708-da6x5rxa	190	28	with	with	IN
cord-258708-da6x5rxa	190	29	severe	severe	JJ
cord-258708-da6x5rxa	190	30	COVID-19	covid-19	NN
cord-258708-da6x5rxa	190	31	.	.	.
cord-258708-da6x5rxa	191	1	Diabetes	diabetes	NN
cord-258708-da6x5rxa	191	2	&	&	CC
cord-258708-da6x5rxa	191	3	metabolic	metabolic	JJ
cord-258708-da6x5rxa	191	4	syndrome	syndrome	NN
cord-258708-da6x5rxa	192	1	The	the	DT
cord-258708-da6x5rxa	192	2	Biomarkers	Biomarkers	NNPS
cord-258708-da6x5rxa	192	3	for	for	IN
cord-258708-da6x5rxa	192	4	Acute	Acute	NNP
cord-258708-da6x5rxa	192	5	Myocardial	Myocardial	NNP
cord-258708-da6x5rxa	192	6	Infarction	Infarction	NNP
cord-258708-da6x5rxa	192	7	and	and	CC
cord-258708-da6x5rxa	192	8	Heart	Heart	NNP
cord-258708-da6x5rxa	192	9	Failure	Failure	NNP
cord-258708-da6x5rxa	192	10	Cardiac	Cardiac	NNP
cord-258708-da6x5rxa	192	11	Involvement	Involvement	NNP
cord-258708-da6x5rxa	192	12	in	in	IN
cord-258708-da6x5rxa	192	13	a	a	DT
cord-258708-da6x5rxa	192	14	Patient	patient	NN
cord-258708-da6x5rxa	192	15	With	with	IN
cord-258708-da6x5rxa	192	16	Coronavirus	Coronavirus	NNP
cord-258708-da6x5rxa	192	17	Disease	Disease	NNP
cord-258708-da6x5rxa	192	18	2019	2019	CD
cord-258708-da6x5rxa	193	1	(	(	-LRB-
cord-258708-da6x5rxa	193	2	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	193	3	)	)	-RRB-
cord-258708-da6x5rxa	193	4	Diagnostic	diagnostic	JJ
cord-258708-da6x5rxa	193	5	utility	utility	NN
cord-258708-da6x5rxa	193	6	of	of	IN
cord-258708-da6x5rxa	193	7	clinical	clinical	JJ
cord-258708-da6x5rxa	193	8	laboratory	laboratory	NN
cord-258708-da6x5rxa	193	9	data	datum	NNS
cord-258708-da6x5rxa	193	10	determinations	determination	NNS
cord-258708-da6x5rxa	193	11	for	for	IN
cord-258708-da6x5rxa	193	12	patients	patient	NNS
cord-258708-da6x5rxa	193	13	with	with	IN
cord-258708-da6x5rxa	193	14	the	the	DT
cord-258708-da6x5rxa	193	15	severe	severe	JJ
cord-258708-da6x5rxa	193	16	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	193	17	Angiotensin	Angiotensin	NNP
cord-258708-da6x5rxa	193	18	-	-	HYPH
cord-258708-da6x5rxa	193	19	Converting	convert	VBG
cord-258708-da6x5rxa	193	20	Enzyme	Enzyme	NNP
cord-258708-da6x5rxa	193	21	2	2	CD
cord-258708-da6x5rxa	193	22	:	:	:
cord-258708-da6x5rxa	193	23	SARS	SARS	NNP
cord-258708-da6x5rxa	193	24	-	-	HYPH
cord-258708-da6x5rxa	193	25	CoV-2	CoV-2	NNP
cord-258708-da6x5rxa	193	26	Receptor	Receptor	NNP
cord-258708-da6x5rxa	193	27	and	and	CC
cord-258708-da6x5rxa	193	28	Regulator	Regulator	NNP
cord-258708-da6x5rxa	193	29	of	of	IN
cord-258708-da6x5rxa	193	30	the	the	DT
cord-258708-da6x5rxa	193	31	Renin	Renin	NNP
cord-258708-da6x5rxa	193	32	-	-	HYPH
cord-258708-da6x5rxa	193	33	Angiotensin	Angiotensin	NNP
cord-258708-da6x5rxa	193	34	System	System	NNP
cord-258708-da6x5rxa	193	35	Cardiovascular	cardiovascular	JJ
cord-258708-da6x5rxa	193	36	complications	complication	NNS
cord-258708-da6x5rxa	193	37	in	in	IN
cord-258708-da6x5rxa	193	38	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	193	39	.	.	.
cord-258708-da6x5rxa	194	1	The	the	DT
cord-258708-da6x5rxa	194	2	American	american	JJ
cord-258708-da6x5rxa	194	3	journal	journal	NN
cord-258708-da6x5rxa	194	4	of	of	IN
cord-258708-da6x5rxa	194	5	emergency	emergency	NN
cord-258708-da6x5rxa	194	6	medicine	medicine	NN
cord-258708-da6x5rxa	194	7	Prognostic	Prognostic	NNP
cord-258708-da6x5rxa	194	8	Value	Value	NNP
cord-258708-da6x5rxa	194	9	of	of	IN
cord-258708-da6x5rxa	194	10	Cardiovascular	Cardiovascular	NNP
cord-258708-da6x5rxa	194	11	Biomarkers	Biomarkers	NNPS
cord-258708-da6x5rxa	194	12	in	in	IN
cord-258708-da6x5rxa	194	13	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	194	14	:	:	:
cord-258708-da6x5rxa	194	15	A	a	DT
cord-258708-da6x5rxa	194	16	Review	Review	NNP
cord-258708-da6x5rxa	194	17	Cardiac	Cardiac	NNP
cord-258708-da6x5rxa	194	18	and	and	CC
cord-258708-da6x5rxa	194	19	arrhythmic	arrhythmic	JJ
cord-258708-da6x5rxa	194	20	complications	complication	NNS
cord-258708-da6x5rxa	194	21	in	in	IN
cord-258708-da6x5rxa	194	22	patients	patient	NNS
cord-258708-da6x5rxa	194	23	with	with	IN
cord-258708-da6x5rxa	194	24	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	194	25	Dynamics	Dynamics	NNPS
cord-258708-da6x5rxa	194	26	of	of	IN
cord-258708-da6x5rxa	194	27	ADAM17-Mediated	ADAM17-Mediated	NNP
cord-258708-da6x5rxa	194	28	Shedding	Shedding	NNP
cord-258708-da6x5rxa	194	29	of	of	IN
cord-258708-da6x5rxa	194	30	ACE2	ACE2	NNP
cord-258708-da6x5rxa	194	31	Applied	Applied	NNP
cord-258708-da6x5rxa	194	32	to	to	IN
cord-258708-da6x5rxa	194	33	Pancreatic	pancreatic	JJ
cord-258708-da6x5rxa	194	34	Islets	Islets	NNPS
cord-258708-da6x5rxa	194	35	of	of	IN
cord-258708-da6x5rxa	194	36	Male	male	NN
cord-258708-da6x5rxa	194	37	db/	db/	XX
cord-258708-da6x5rxa	195	1	db	db	NNP
cord-258708-da6x5rxa	195	2	Mice	Mice	NNP
cord-258708-da6x5rxa	196	1	Circulating	circulate	VBG
cord-258708-da6x5rxa	196	2	plasma	plasma	NN
cord-258708-da6x5rxa	196	3	concentrations	concentration	NNS
cord-258708-da6x5rxa	196	4	of	of	IN
cord-258708-da6x5rxa	196	5	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	196	6	-	-	HYPH
cord-258708-da6x5rxa	196	7	converting	convert	VBG
cord-258708-da6x5rxa	196	8	enzyme	enzyme	NN
cord-258708-da6x5rxa	196	9	2	2	CD
cord-258708-da6x5rxa	196	10	in	in	IN
cord-258708-da6x5rxa	196	11	men	man	NNS
cord-258708-da6x5rxa	196	12	and	and	CC
cord-258708-da6x5rxa	196	13	women	woman	NNS
cord-258708-da6x5rxa	196	14	with	with	IN
cord-258708-da6x5rxa	196	15	heart	heart	NN
cord-258708-da6x5rxa	196	16	failure	failure	NN
cord-258708-da6x5rxa	196	17	and	and	CC
cord-258708-da6x5rxa	196	18	effects	effect	NNS
cord-258708-da6x5rxa	196	19	of	of	IN
cord-258708-da6x5rxa	196	20	renin	renin	NN
cord-258708-da6x5rxa	196	21	-	-	HYPH
cord-258708-da6x5rxa	196	22	angiotensin	angiotensin	NN
cord-258708-da6x5rxa	196	23	-	-	HYPH
cord-258708-da6x5rxa	196	24	aldosterone	aldosterone	NN
cord-258708-da6x5rxa	196	25	inhibitors	inhibitor	NNS
cord-258708-da6x5rxa	197	1	COVID-19	covid-19	JJ
cord-258708-da6x5rxa	197	2	infection	infection	NN
cord-258708-da6x5rxa	197	3	induces	induce	VBZ
cord-258708-da6x5rxa	197	4	readily	readily	RB
cord-258708-da6x5rxa	197	5	detectable	detectable	JJ
cord-258708-da6x5rxa	197	6	morphological	morphological	JJ
cord-258708-da6x5rxa	197	7	and	and	CC
cord-258708-da6x5rxa	197	8	inflammation	inflammation	NN
cord-258708-da6x5rxa	197	9	-	-	HYPH
cord-258708-da6x5rxa	197	10	related	relate	VBN
cord-258708-da6x5rxa	197	11	phenotypic	phenotypic	JJ
cord-258708-da6x5rxa	197	12	changes	change	NNS
cord-258708-da6x5rxa	197	13	in	in	IN
cord-258708-da6x5rxa	197	14	peripheral	peripheral	JJ
cord-258708-da6x5rxa	197	15	blood	blood	NN
cord-258708-da6x5rxa	197	16	monocytes	monocyte	NNS
cord-258708-da6x5rxa	197	17	,	,	,
cord-258708-da6x5rxa	197	18	the	the	DT
cord-258708-da6x5rxa	197	19	severity	severity	NN
cord-258708-da6x5rxa	197	20	of	of	IN
cord-258708-da6x5rxa	197	21	which	which	WDT
cord-258708-da6x5rxa	197	22	correlate	correlate	VBP
cord-258708-da6x5rxa	197	23	with	with	IN
cord-258708-da6x5rxa	197	24	patient	patient	NN
cord-258708-da6x5rxa	197	25	outcome	outcome	NN
cord-258708-da6x5rxa	197	26	Cardiovascular	cardiovascular	JJ
cord-258708-da6x5rxa	197	27	complications	complication	NNS
cord-258708-da6x5rxa	197	28	in	in	IN
cord-258708-da6x5rxa	197	29	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	197	30	.	.	.
cord-258708-da6x5rxa	198	1	The	the	DT
cord-258708-da6x5rxa	198	2	American	american	JJ
cord-258708-da6x5rxa	198	3	journal	journal	NN
cord-258708-da6x5rxa	198	4	of	of	IN
cord-258708-da6x5rxa	198	5	emergency	emergency	NN
cord-258708-da6x5rxa	198	6	medicine	medicine	NN
cord-258708-da6x5rxa	199	1	The	the	DT
cord-258708-da6x5rxa	199	2	epidemiology	epidemiology	NN
cord-258708-da6x5rxa	199	3	and	and	CC
cord-258708-da6x5rxa	199	4	pathogenesis	pathogenesis	NN
cord-258708-da6x5rxa	199	5	of	of	IN
cord-258708-da6x5rxa	199	6	coronavirus	coronavirus	NN
cord-258708-da6x5rxa	199	7	disease	disease	NN
cord-258708-da6x5rxa	199	8	(	(	-LRB-
cord-258708-da6x5rxa	199	9	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	199	10	)	)	-RRB-
cord-258708-da6x5rxa	199	11	outbreak	outbreak	NN
cord-258708-da6x5rxa	199	12	Description	description	NN
cord-258708-da6x5rxa	199	13	and	and	CC
cord-258708-da6x5rxa	199	14	Proposed	Proposed	NNP
cord-258708-da6x5rxa	199	15	Management	Management	NNP
cord-258708-da6x5rxa	199	16	of	of	IN
cord-258708-da6x5rxa	199	17	the	the	DT
cord-258708-da6x5rxa	199	18	Acute	Acute	NNP
cord-258708-da6x5rxa	199	19	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	199	20	Cardiovascular	Cardiovascular	NNP
cord-258708-da6x5rxa	199	21	Syndrome	Syndrome	NNP
cord-258708-da6x5rxa	199	22	Recognition	Recognition	NNP
cord-258708-da6x5rxa	199	23	and	and	CC
cord-258708-da6x5rxa	199	24	Initial	Initial	NNP
cord-258708-da6x5rxa	199	25	Management	Management	NNP
cord-258708-da6x5rxa	199	26	of	of	IN
cord-258708-da6x5rxa	199	27	Fulminant	Fulminant	NNP
cord-258708-da6x5rxa	199	28	Myocarditis	Myocarditis	NNP
cord-258708-da6x5rxa	199	29	:	:	:
cord-258708-da6x5rxa	199	30	A	a	DT
cord-258708-da6x5rxa	199	31	Scientific	Scientific	NNP
cord-258708-da6x5rxa	199	32	Statement	statement	NN
cord-258708-da6x5rxa	199	33	From	from	IN
cord-258708-da6x5rxa	199	34	the	the	DT
cord-258708-da6x5rxa	199	35	COVID-19	covid-19	JJ
cord-258708-da6x5rxa	199	36	and	and	CC
cord-258708-da6x5rxa	199	37	acute	acute	JJ
cord-258708-da6x5rxa	199	38	myocardial	myocardial	JJ
cord-258708-da6x5rxa	199	39	injury	injury	NN
cord-258708-da6x5rxa	199	40	:	:	:
cord-258708-da6x5rxa	199	41	the	the	DT
cord-258708-da6x5rxa	199	42	heart	heart	NN
cord-258708-da6x5rxa	199	43	of	of	IN
cord-258708-da6x5rxa	199	44	the	the	DT
cord-258708-da6x5rxa	199	45	matter	matter	NN
cord-258708-da6x5rxa	199	46	or	or	CC
cord-258708-da6x5rxa	199	47	an	an	DT
cord-258708-da6x5rxa	199	48	innocent	innocent	JJ
cord-258708-da6x5rxa	199	49	bystander	bystander	NN
cord-258708-da6x5rxa	199	50	?	?	.
cord-258708-da6x5rxa	200	1	Heart	Heart	NNP
cord-258708-da6x5rxa	200	2	Bedside	Bedside	NNP
cord-258708-da6x5rxa	200	3	Focused	focus	VBD
cord-258708-da6x5rxa	200	4	Cardiac	Cardiac	NNP
cord-258708-da6x5rxa	200	5	Ultrasound	Ultrasound	NNP
cord-258708-da6x5rxa	200	6	in	in	IN
cord-258708-da6x5rxa	200	7	COVID-19	COVID-19	NNP
cord-258708-da6x5rxa	200	8	from	from	IN
cord-258708-da6x5rxa	200	9	the	the	DT
cord-258708-da6x5rxa	200	10	Wuhan	Wuhan	NNP
cord-258708-da6x5rxa	200	11	Epicenter	Epicenter	NNP
cord-258708-da6x5rxa	200	12	:	:	.
cord-258708-da6x5rxa	201	1	The	the	DT
cord-258708-da6x5rxa	201	2	Role	role	NN
cord-258708-da6x5rxa	201	3	of	of	IN
cord-258708-da6x5rxa	201	4	Cardiac	Cardiac	NNP
cord-258708-da6x5rxa	201	5	Point	Point	NNP
cord-258708-da6x5rxa	201	6	-	-	HYPH
cord-258708-da6x5rxa	201	7	of	of	IN
cord-258708-da6x5rxa	201	8	-	-	HYPH
cord-258708-da6x5rxa	201	9	Care	care	NN
cord-258708-da6x5rxa	201	10	Ultrasound	Ultrasound	NNP
cord-258708-da6x5rxa	201	11	,	,	,
cord-258708-da6x5rxa	201	12	Limited	Limited	NNP
cord-258708-da6x5rxa	201	13	Transthoracic	Transthoracic	NNP
cord-258708-da6x5rxa	201	14	Echocardiography	Echocardiography	NNP
cord-258708-da6x5rxa	201	15	,	,	,
cord-258708-da6x5rxa	201	16	and	and	CC
cord-258708-da6x5rxa	201	17	Critical	Critical	NNP
cord-258708-da6x5rxa	201	18	Care	Care	NNP
cord-258708-da6x5rxa	201	19	Echocardiography	echocardiography	NN