id sid tid token lemma pos cord-254436-89zf41xr 1 1 key key JJ cord-254436-89zf41xr 1 2 : : : cord-254436-89zf41xr 1 3 cord-254436 cord-254436 NNP cord-254436-89zf41xr 1 4 - - HYPH cord-254436-89zf41xr 1 5 89zf41xr 89zf41xr CD cord-254436-89zf41xr 1 6 authors author NNS cord-254436-89zf41xr 1 7 : : : cord-254436-89zf41xr 1 8 Singer singer NN cord-254436-89zf41xr 1 9 , , , cord-254436-89zf41xr 1 10 Professor Professor NNP cord-254436-89zf41xr 1 11 Donald Donald NNP cord-254436-89zf41xr 1 12 RJ RJ NNP cord-254436-89zf41xr 1 13 title title NN cord-254436-89zf41xr 1 14 : : : cord-254436-89zf41xr 1 15 Health health NN cord-254436-89zf41xr 1 16 policy policy NN cord-254436-89zf41xr 1 17 implications implication NNS cord-254436-89zf41xr 1 18 of of IN cord-254436-89zf41xr 1 19 the the DT cord-254436-89zf41xr 1 20 links link NNS cord-254436-89zf41xr 1 21 between between IN cord-254436-89zf41xr 1 22 cardiovascular cardiovascular JJ cord-254436-89zf41xr 1 23 risk risk NN cord-254436-89zf41xr 1 24 and and CC cord-254436-89zf41xr 1 25 COVID-19 covid-19 CD cord-254436-89zf41xr 1 26 date date NN cord-254436-89zf41xr 1 27 : : : cord-254436-89zf41xr 1 28 2020 2020 CD cord-254436-89zf41xr 1 29 - - HYPH cord-254436-89zf41xr 1 30 09 09 CD cord-254436-89zf41xr 1 31 - - HYPH cord-254436-89zf41xr 1 32 03 03 CD cord-254436-89zf41xr 1 33 journal journal NN cord-254436-89zf41xr 1 34 : : : cord-254436-89zf41xr 1 35 Health Health NNP cord-254436-89zf41xr 1 36 Policy Policy NNP cord-254436-89zf41xr 1 37 Technol Technol NNP cord-254436-89zf41xr 1 38 DOI doi NN cord-254436-89zf41xr 1 39 : : : cord-254436-89zf41xr 1 40 10.1016/ 10.1016/ CD cord-254436-89zf41xr 2 1 j.hlpt.2020.09.001 j.hlpt.2020.09.001 NNP cord-254436-89zf41xr 3 1 sha sha NNP cord-254436-89zf41xr 3 2 : : : cord-254436-89zf41xr 4 1 dfe72879771d2333484b9f6280255a3155c63aba dfe72879771d2333484b9f6280255a3155c63aba NNP cord-254436-89zf41xr 4 2 doc_id doc_id CD cord-254436-89zf41xr 4 3 : : : cord-254436-89zf41xr 5 1 254436 254436 CD cord-254436-89zf41xr 5 2 cord_uid cord_uid NNS cord-254436-89zf41xr 5 3 : : : cord-254436-89zf41xr 5 4 89zf41xr 89zf41xr CD cord-254436-89zf41xr 6 1 nan nan NNP cord-254436-89zf41xr 6 2 influenza influenza NN cord-254436-89zf41xr 6 3 by by IN cord-254436-89zf41xr 6 4 immunization immunization NN cord-254436-89zf41xr 6 5 now now RB cord-254436-89zf41xr 6 6 have have VBP cord-254436-89zf41xr 6 7 reduced reduce VBN cord-254436-89zf41xr 6 8 confidence confidence NN cord-254436-89zf41xr 6 9 in in IN cord-254436-89zf41xr 6 10 leaving leave VBG cord-254436-89zf41xr 6 11 home home NN cord-254436-89zf41xr 6 12 . . . cord-254436-89zf41xr 7 1 They -PRON- PRP cord-254436-89zf41xr 7 2 are be VBP cord-254436-89zf41xr 7 3 therefore therefore RB cord-254436-89zf41xr 7 4 much much RB cord-254436-89zf41xr 7 5 less less RBR cord-254436-89zf41xr 7 6 likely likely JJ cord-254436-89zf41xr 7 7 to to TO cord-254436-89zf41xr 7 8 be be VB cord-254436-89zf41xr 7 9 prepared prepared JJ cord-254436-89zf41xr 7 10 to to TO cord-254436-89zf41xr 7 11 access access VB cord-254436-89zf41xr 7 12 community community NN cord-254436-89zf41xr 7 13 health health NN cord-254436-89zf41xr 7 14 services service NNS cord-254436-89zf41xr 7 15 to to TO cord-254436-89zf41xr 7 16 receive receive VB cord-254436-89zf41xr 7 17 an an DT cord-254436-89zf41xr 7 18 influenza influenza NN cord-254436-89zf41xr 7 19 immunization immunization NN cord-254436-89zf41xr 7 20 . . . cord-254436-89zf41xr 8 1 An an DT cord-254436-89zf41xr 8 2 epidemic epidemic NN cord-254436-89zf41xr 8 3 of of IN cord-254436-89zf41xr 8 4 simultaneous simultaneous JJ cord-254436-89zf41xr 8 5 influenza influenza NN cord-254436-89zf41xr 8 6 and and CC cord-254436-89zf41xr 8 7 COVID-19 COVID-19 NNP cord-254436-89zf41xr 8 8 is be VBZ cord-254436-89zf41xr 8 9 therefore therefore RB cord-254436-89zf41xr 8 10 a a DT cord-254436-89zf41xr 8 11 serious serious JJ cord-254436-89zf41xr 8 12 concern concern NN cord-254436-89zf41xr 8 13 . . . cord-254436-89zf41xr 9 1 This this DT cord-254436-89zf41xr 9 2 would would MD cord-254436-89zf41xr 9 3 result result VB cord-254436-89zf41xr 9 4 in in IN cord-254436-89zf41xr 9 5 higher high JJR cord-254436-89zf41xr 9 6 morbidity morbidity NN cord-254436-89zf41xr 9 7 and and CC cord-254436-89zf41xr 9 8 mortality mortality NN cord-254436-89zf41xr 9 9 in in IN cord-254436-89zf41xr 9 10 vulnerable vulnerable JJ cord-254436-89zf41xr 9 11 people people NNS cord-254436-89zf41xr 9 12 and and CC cord-254436-89zf41xr 9 13 greater great JJR cord-254436-89zf41xr 9 14 pressure pressure NN cord-254436-89zf41xr 9 15 on on IN cord-254436-89zf41xr 9 16 acute acute JJ cord-254436-89zf41xr 9 17 medical medical JJ cord-254436-89zf41xr 9 18 services service NNS cord-254436-89zf41xr 9 19 . . . cord-254436-89zf41xr 10 1 Approaches approach NNS cord-254436-89zf41xr 10 2 to to IN cord-254436-89zf41xr 10 3 improving improve VBG cord-254436-89zf41xr 10 4 outcomes outcome NNS cord-254436-89zf41xr 10 5 of of IN cord-254436-89zf41xr 10 6 COVID-19 covid-19 DT cord-254436-89zf41xr 10 7 include include VBP cord-254436-89zf41xr 10 8 development development NN cord-254436-89zf41xr 10 9 of of IN cord-254436-89zf41xr 10 10 effective effective JJ cord-254436-89zf41xr 10 11 vaccines vaccine NNS cord-254436-89zf41xr 10 12 . . . cord-254436-89zf41xr 11 1 In in IN cord-254436-89zf41xr 11 2 the the DT cord-254436-89zf41xr 11 3 meantime meantime NN cord-254436-89zf41xr 11 4 , , , cord-254436-89zf41xr 11 5 public public JJ cord-254436-89zf41xr 11 6 health health NN cord-254436-89zf41xr 11 7 measures measure NNS cord-254436-89zf41xr 11 8 are be VBP cord-254436-89zf41xr 11 9 the the DT cord-254436-89zf41xr 11 10 mainstay mainstay NN cord-254436-89zf41xr 11 11 for for IN cord-254436-89zf41xr 11 12 containing contain VBG cord-254436-89zf41xr 11 13 spread spread NN cord-254436-89zf41xr 11 14 of of IN cord-254436-89zf41xr 11 15 infection infection NN cord-254436-89zf41xr 11 16 with with IN cord-254436-89zf41xr 11 17 SARS SARS NNP cord-254436-89zf41xr 11 18 - - HYPH cord-254436-89zf41xr 11 19 CoV-2 CoV-2 NNP cord-254436-89zf41xr 11 20 , , , cord-254436-89zf41xr 11 21 complemented complement VBN cord-254436-89zf41xr 11 22 by by IN cord-254436-89zf41xr 11 23 access access NN cord-254436-89zf41xr 11 24 to to IN cord-254436-89zf41xr 11 25 high high JJ cord-254436-89zf41xr 11 26 quality quality NN cord-254436-89zf41xr 11 27 supportive supportive JJ cord-254436-89zf41xr 11 28 treatment treatment NN cord-254436-89zf41xr 11 29 and and CC cord-254436-89zf41xr 11 30 efforts effort NNS cord-254436-89zf41xr 11 31 to to TO cord-254436-89zf41xr 11 32 develop develop VB cord-254436-89zf41xr 11 33 targeted target VBN cord-254436-89zf41xr 11 34 approaches approach NNS cord-254436-89zf41xr 11 35 to to TO cord-254436-89zf41xr 11 36 reduce reduce VB cord-254436-89zf41xr 11 37 infection infection NN cord-254436-89zf41xr 11 38 and and CC cord-254436-89zf41xr 11 39 disease disease NN cord-254436-89zf41xr 11 40 severity severity NN cord-254436-89zf41xr 11 41 in in IN cord-254436-89zf41xr 11 42 people people NNS cord-254436-89zf41xr 11 43 at at IN cord-254436-89zf41xr 11 44 high high JJ cord-254436-89zf41xr 11 45 risk risk NN cord-254436-89zf41xr 11 46 of of IN cord-254436-89zf41xr 11 47 serious serious JJ cord-254436-89zf41xr 11 48 morbidity morbidity NN cord-254436-89zf41xr 11 49 and and CC cord-254436-89zf41xr 11 50 death death NN cord-254436-89zf41xr 11 51 from from IN cord-254436-89zf41xr 11 52 COVID-19 COVID-19 NNP cord-254436-89zf41xr 11 53 . . . cord-254436-89zf41xr 12 1 However however RB cord-254436-89zf41xr 12 2 , , , cord-254436-89zf41xr 12 3 eight eight CD cord-254436-89zf41xr 12 4 months month NNS cord-254436-89zf41xr 12 5 since since IN cord-254436-89zf41xr 12 6 this this DT cord-254436-89zf41xr 12 7 new new JJ cord-254436-89zf41xr 12 8 respiratory respiratory JJ cord-254436-89zf41xr 12 9 syndrome syndrome NN cord-254436-89zf41xr 12 10 was be VBD cord-254436-89zf41xr 12 11 first first RB cord-254436-89zf41xr 12 12 reported report VBN cord-254436-89zf41xr 12 13 to to IN cord-254436-89zf41xr 12 14 international international JJ cord-254436-89zf41xr 12 15 authorities authority NNS cord-254436-89zf41xr 12 16 , , , cord-254436-89zf41xr 12 17 effective effective JJ cord-254436-89zf41xr 12 18 test test NN cord-254436-89zf41xr 12 19 and and CC cord-254436-89zf41xr 12 20 trace trace NN cord-254436-89zf41xr 12 21 systems system NNS cord-254436-89zf41xr 12 22 have have VBP cord-254436-89zf41xr 12 23 not not RB cord-254436-89zf41xr 12 24 yet yet RB cord-254436-89zf41xr 12 25 been be VBN cord-254436-89zf41xr 12 26 internationally internationally RB cord-254436-89zf41xr 12 27 implemented implement VBN cord-254436-89zf41xr 12 28 , , , cord-254436-89zf41xr 12 29 even even RB cord-254436-89zf41xr 12 30 across across IN cord-254436-89zf41xr 12 31 all all RB cord-254436-89zf41xr 12 32 well well RB cord-254436-89zf41xr 12 33 - - HYPH cord-254436-89zf41xr 12 34 developed develop VBN cord-254436-89zf41xr 12 35 healthcare healthcare NN cord-254436-89zf41xr 12 36 systems system NNS cord-254436-89zf41xr 12 37 . . . cord-254436-89zf41xr 13 1 For for IN cord-254436-89zf41xr 13 2 example example NN cord-254436-89zf41xr 13 3 , , , cord-254436-89zf41xr 13 4 in in IN cord-254436-89zf41xr 13 5 the the DT cord-254436-89zf41xr 13 6 UK UK NNP cord-254436-89zf41xr 13 7 , , , cord-254436-89zf41xr 13 8 reporting report VBG cord-254436-89zf41xr 13 9 of of IN cord-254436-89zf41xr 13 10 test test NN cord-254436-89zf41xr 13 11 results result NNS cord-254436-89zf41xr 13 12 has have VBZ cord-254436-89zf41xr 13 13 fallen fall VBN cord-254436-89zf41xr 13 14 to to IN cord-254436-89zf41xr 13 15 below below IN cord-254436-89zf41xr 13 16 50 50 CD cord-254436-89zf41xr 13 17 % % NN cord-254436-89zf41xr 13 18 within within IN cord-254436-89zf41xr 13 19 24 24 CD cord-254436-89zf41xr 13 20 hours hour NNS cord-254436-89zf41xr 13 21 and and CC cord-254436-89zf41xr 13 22 one one CD cord-254436-89zf41xr 13 23 in in IN cord-254436-89zf41xr 13 24 seven seven CD cord-254436-89zf41xr 13 25 home home NN cord-254436-89zf41xr 13 26 testing testing NN cord-254436-89zf41xr 13 27 kits kit NNS cord-254436-89zf41xr 13 28 are be VBP cord-254436-89zf41xr 13 29 reported report VBN cord-254436-89zf41xr 13 30 to to TO cord-254436-89zf41xr 13 31 fail fail VB cord-254436-89zf41xr 13 32 to to TO cord-254436-89zf41xr 13 33 yield yield VB cord-254436-89zf41xr 13 34 a a DT cord-254436-89zf41xr 13 35 result result NN cord-254436-89zf41xr 13 36 [ [ -LRB- cord-254436-89zf41xr 13 37 3 3 CD cord-254436-89zf41xr 13 38 ] ] -RRB- cord-254436-89zf41xr 13 39 . . . cord-254436-89zf41xr 14 1 There there EX cord-254436-89zf41xr 14 2 are be VBP cord-254436-89zf41xr 14 3 major major JJ cord-254436-89zf41xr 14 4 global global JJ cord-254436-89zf41xr 14 5 efforts effort NNS cord-254436-89zf41xr 14 6 underway underway JJ cord-254436-89zf41xr 14 7 to to TO cord-254436-89zf41xr 14 8 develop develop VB cord-254436-89zf41xr 14 9 vaccines vaccine NNS cord-254436-89zf41xr 14 10 against against IN cord-254436-89zf41xr 14 11 COVID-19 COVID-19 NNP cord-254436-89zf41xr 14 12 , , , cord-254436-89zf41xr 14 13 with with IN cord-254436-89zf41xr 14 14 19 19 CD cord-254436-89zf41xr 14 15 candidates candidate NNS cord-254436-89zf41xr 14 16 as as IN cord-254436-89zf41xr 14 17 of of IN cord-254436-89zf41xr 14 18 31 31 CD cord-254436-89zf41xr 14 19 July July NNP cord-254436-89zf41xr 14 20 2020 2020 CD cord-254436-89zf41xr 14 21 entered enter VBD cord-254436-89zf41xr 14 22 into into IN cord-254436-89zf41xr 14 23 clinical clinical JJ cord-254436-89zf41xr 14 24 studies study NNS cord-254436-89zf41xr 14 25 , , , cord-254436-89zf41xr 14 26 including include VBG cord-254436-89zf41xr 14 27 phase phase NN cord-254436-89zf41xr 14 28 2 2 CD cord-254436-89zf41xr 14 29 and and CC cord-254436-89zf41xr 14 30 3 3 CD cord-254436-89zf41xr 14 31 trials trial NNS cord-254436-89zf41xr 14 32 [ [ -LRB- cord-254436-89zf41xr 14 33 4 4 CD cord-254436-89zf41xr 14 34 ] ] -RRB- cord-254436-89zf41xr 14 35 . . . cord-254436-89zf41xr 15 1 However however RB cord-254436-89zf41xr 15 2 , , , cord-254436-89zf41xr 15 3 their -PRON- PRP$ cord-254436-89zf41xr 15 4 short short JJ cord-254436-89zf41xr 15 5 and and CC cord-254436-89zf41xr 15 6 long long JJ cord-254436-89zf41xr 15 7 - - HYPH cord-254436-89zf41xr 15 8 term term NN cord-254436-89zf41xr 15 9 effectiveness effectiveness NN cord-254436-89zf41xr 15 10 and and CC cord-254436-89zf41xr 15 11 safety safety NN cord-254436-89zf41xr 15 12 remain remain VBP cord-254436-89zf41xr 15 13 to to TO cord-254436-89zf41xr 15 14 be be VB cord-254436-89zf41xr 15 15 established establish VBN cord-254436-89zf41xr 15 16 . . . cord-254436-89zf41xr 16 1 The the DT cord-254436-89zf41xr 16 2 usual usual JJ cord-254436-89zf41xr 16 3 questions question NNS cord-254436-89zf41xr 16 4 for for IN cord-254436-89zf41xr 16 5 a a DT cord-254436-89zf41xr 16 6 new new JJ cord-254436-89zf41xr 16 7 vaccine vaccine NN cord-254436-89zf41xr 16 8 remain remain VBP cord-254436-89zf41xr 16 9 to to TO cord-254436-89zf41xr 16 10 be be VB cord-254436-89zf41xr 16 11 answered answer VBN cord-254436-89zf41xr 16 12 . . . cord-254436-89zf41xr 17 1 Will Will MD cord-254436-89zf41xr 17 2 vaccines vaccine NNS cord-254436-89zf41xr 17 3 prevent prevent VB cord-254436-89zf41xr 17 4 COVID-19 covid-19 CD cord-254436-89zf41xr 17 5 or or CC cord-254436-89zf41xr 17 6 at at IN cord-254436-89zf41xr 17 7 least least JJS cord-254436-89zf41xr 17 8 improve improve VB cord-254436-89zf41xr 17 9 prognosis prognosis NN cord-254436-89zf41xr 17 10 from from IN cord-254436-89zf41xr 17 11 the the DT cord-254436-89zf41xr 17 12 infection infection NN cord-254436-89zf41xr 17 13 ? ? . cord-254436-89zf41xr 18 1 Will Will MD cord-254436-89zf41xr 18 2 groups group NNS cord-254436-89zf41xr 18 3 at at IN cord-254436-89zf41xr 18 4 higher high JJR cord-254436-89zf41xr 18 5 risk risk NN cord-254436-89zf41xr 18 6 from from IN cord-254436-89zf41xr 18 7 COVID-19 COVID-19 NNP cord-254436-89zf41xr 18 8 respond respond NNS cord-254436-89zf41xr 18 9 as as RB cord-254436-89zf41xr 18 10 well well RB cord-254436-89zf41xr 18 11 as as IN cord-254436-89zf41xr 18 12 the the DT cord-254436-89zf41xr 18 13 often often RB cord-254436-89zf41xr 18 14 healthier healthy JJR cord-254436-89zf41xr 18 15 volunteers volunteer NNS cord-254436-89zf41xr 18 16 in in IN cord-254436-89zf41xr 18 17 clinical clinical JJ cord-254436-89zf41xr 18 18 trials trial NNS cord-254436-89zf41xr 18 19 ? ? . cord-254436-89zf41xr 19 1 The the DT cord-254436-89zf41xr 19 2 timeline timeline NN cord-254436-89zf41xr 19 3 also also RB cord-254436-89zf41xr 19 4 remains remain VBZ cord-254436-89zf41xr 19 5 uncertain uncertain JJ cord-254436-89zf41xr 19 6 for for IN cord-254436-89zf41xr 19 7 widespread widespread JJ cord-254436-89zf41xr 19 8 public public JJ cord-254436-89zf41xr 19 9 protection protection NN cord-254436-89zf41xr 19 10 if if IN cord-254436-89zf41xr 19 11 and and CC cord-254436-89zf41xr 19 12 when when WRB cord-254436-89zf41xr 19 13 safe safe JJ cord-254436-89zf41xr 19 14 and and CC cord-254436-89zf41xr 19 15 effective effective JJ cord-254436-89zf41xr 19 16 vaccines vaccine NNS cord-254436-89zf41xr 19 17 become become VBP cord-254436-89zf41xr 19 18 available available JJ cord-254436-89zf41xr 19 19 . . . cord-254436-89zf41xr 20 1 International international JJ cord-254436-89zf41xr 20 2 networks network NNS cord-254436-89zf41xr 20 3 for for IN cord-254436-89zf41xr 20 4 pharmacovigilance pharmacovigilance NN cord-254436-89zf41xr 20 5 against against IN cord-254436-89zf41xr 20 6 adverse adverse JJ cord-254436-89zf41xr 20 7 effects effect NNS cord-254436-89zf41xr 20 8 of of IN cord-254436-89zf41xr 20 9 COVID-19 covid-19 JJ cord-254436-89zf41xr 20 10 vaccines vaccine NNS cord-254436-89zf41xr 20 11 are be VBP cord-254436-89zf41xr 20 12 needed need VBN cord-254436-89zf41xr 20 13 , , , cord-254436-89zf41xr 20 14 with with IN cord-254436-89zf41xr 20 15 for for IN cord-254436-89zf41xr 20 16 example example NN cord-254436-89zf41xr 20 17 Utrecht Utrecht NNP cord-254436-89zf41xr 20 18 University University NNP cord-254436-89zf41xr 20 19 in in IN cord-254436-89zf41xr 20 20 The the DT cord-254436-89zf41xr 20 21 Netherlands Netherlands NNP cord-254436-89zf41xr 20 22 being be VBG cord-254436-89zf41xr 20 23 commissioned commission VBN cord-254436-89zf41xr 20 24 by by IN cord-254436-89zf41xr 20 25 the the DT cord-254436-89zf41xr 20 26 European European NNP cord-254436-89zf41xr 20 27 Medicines Medicines NNPS cord-254436-89zf41xr 20 28 Agency Agency NNP cord-254436-89zf41xr 20 29 as as IN cord-254436-89zf41xr 20 30 a a DT cord-254436-89zf41xr 20 31 hub hub NN cord-254436-89zf41xr 20 32 for for IN cord-254436-89zf41xr 20 33 a a DT cord-254436-89zf41xr 20 34 Europe Europe NNP cord-254436-89zf41xr 20 35 - - HYPH cord-254436-89zf41xr 20 36 wide wide JJ cord-254436-89zf41xr 20 37 network network NN cord-254436-89zf41xr 20 38 [ [ -LRB- cord-254436-89zf41xr 20 39 5 5 CD cord-254436-89zf41xr 20 40 ] ] -RRB- cord-254436-89zf41xr 20 41 . . . cord-254436-89zf41xr 21 1 People People NNS cord-254436-89zf41xr 21 2 with with IN cord-254436-89zf41xr 21 3 comorbidities comorbiditie NNS cord-254436-89zf41xr 21 4 are be VBP cord-254436-89zf41xr 21 5 more more RBR cord-254436-89zf41xr 21 6 likely likely JJ cord-254436-89zf41xr 21 7 to to TO cord-254436-89zf41xr 21 8 be be VB cord-254436-89zf41xr 21 9 infected infect VBN cord-254436-89zf41xr 21 10 with with IN cord-254436-89zf41xr 21 11 SARS SARS NNP cord-254436-89zf41xr 21 12 - - HYPH cord-254436-89zf41xr 21 13 CoV-2 CoV-2 NNP cord-254436-89zf41xr 21 14 , , , cord-254436-89zf41xr 21 15 especially especially RB cord-254436-89zf41xr 21 16 those those DT cord-254436-89zf41xr 21 17 with with IN cord-254436-89zf41xr 21 18 hypertension hypertension NN cord-254436-89zf41xr 21 19 , , , cord-254436-89zf41xr 21 20 coronary coronary JJ cord-254436-89zf41xr 21 21 heart heart NN cord-254436-89zf41xr 21 22 disease disease NN cord-254436-89zf41xr 21 23 , , , cord-254436-89zf41xr 21 24 diabetes diabete VBZ cord-254436-89zf41xr 21 25 mellitus mellitus NN cord-254436-89zf41xr 21 26 and and CC cord-254436-89zf41xr 21 27 obesity obesity NN cord-254436-89zf41xr 21 28 . . . cord-254436-89zf41xr 22 1 They -PRON- PRP cord-254436-89zf41xr 22 2 are be VBP cord-254436-89zf41xr 22 3 also also RB cord-254436-89zf41xr 22 4 more more RBR cord-254436-89zf41xr 22 5 likely likely JJ cord-254436-89zf41xr 22 6 to to TO cord-254436-89zf41xr 22 7 have have VB cord-254436-89zf41xr 22 8 worse bad JJR cord-254436-89zf41xr 22 9 outcomes outcome NNS cord-254436-89zf41xr 22 10 from from IN cord-254436-89zf41xr 22 11 COVID-19 COVID-19 NNP cord-254436-89zf41xr 22 12 , , , cord-254436-89zf41xr 22 13 with with IN cord-254436-89zf41xr 22 14 similar similar JJ cord-254436-89zf41xr 22 15 associations association NNS cord-254436-89zf41xr 22 16 in in IN cord-254436-89zf41xr 22 17 reports report NNS cord-254436-89zf41xr 22 18 for for IN cord-254436-89zf41xr 22 19 example example NN cord-254436-89zf41xr 22 20 from from IN cord-254436-89zf41xr 22 21 China China NNP cord-254436-89zf41xr 22 22 , , , cord-254436-89zf41xr 22 23 the the DT cord-254436-89zf41xr 22 24 USA USA NNP cord-254436-89zf41xr 22 25 and and CC cord-254436-89zf41xr 22 26 Italy Italy NNP cord-254436-89zf41xr 22 27 [ [ -LRB- cord-254436-89zf41xr 22 28 6 6 CD cord-254436-89zf41xr 22 29 , , , cord-254436-89zf41xr 22 30 7 7 CD cord-254436-89zf41xr 22 31 ] ] -RRB- cord-254436-89zf41xr 22 32 . . . cord-254436-89zf41xr 23 1 People People NNS cord-254436-89zf41xr 23 2 with with IN cord-254436-89zf41xr 23 3 cardiovascular cardiovascular JJ cord-254436-89zf41xr 23 4 risk risk NN cord-254436-89zf41xr 23 5 factors factor NNS cord-254436-89zf41xr 23 6 or or CC cord-254436-89zf41xr 23 7 established establish VBD cord-254436-89zf41xr 23 8 cardiovascular cardiovascular JJ cord-254436-89zf41xr 23 9 disease disease NN cord-254436-89zf41xr 23 10 also also RB cord-254436-89zf41xr 23 11 experience experience VBP cord-254436-89zf41xr 23 12 a a DT cord-254436-89zf41xr 23 13 high high JJ cord-254436-89zf41xr 23 14 case case NN cord-254436-89zf41xr 23 15 - - HYPH cord-254436-89zf41xr 23 16 fatality fatality NN cord-254436-89zf41xr 23 17 rate rate NN cord-254436-89zf41xr 23 18 from from IN cord-254436-89zf41xr 23 19 COVID-19 COVID-19 NNP cord-254436-89zf41xr 23 20 [ [ -LRB- cord-254436-89zf41xr 23 21 5 5 CD cord-254436-89zf41xr 23 22 , , , cord-254436-89zf41xr 23 23 6 6 CD cord-254436-89zf41xr 23 24 ] ] -RRB- cord-254436-89zf41xr 23 25 . . . cord-254436-89zf41xr 24 1 For for IN cord-254436-89zf41xr 24 2 example example NN cord-254436-89zf41xr 24 3 , , , cord-254436-89zf41xr 24 4 hypertension hypertension NN cord-254436-89zf41xr 24 5 was be VBD cord-254436-89zf41xr 24 6 reported report VBN cord-254436-89zf41xr 24 7 in in IN cord-254436-89zf41xr 24 8 40 40 CD cord-254436-89zf41xr 24 9 % % NN cord-254436-89zf41xr 24 10 of of IN cord-254436-89zf41xr 24 11 patients patient NNS cord-254436-89zf41xr 24 12 who who WP cord-254436-89zf41xr 24 13 died die VBD cord-254436-89zf41xr 24 14 [ [ -LRB- cord-254436-89zf41xr 24 15 odds odd NNS cord-254436-89zf41xr 24 16 ratio ratio NN cord-254436-89zf41xr 24 17 for for IN cord-254436-89zf41xr 24 18 death death NN cord-254436-89zf41xr 24 19 , , , cord-254436-89zf41xr 24 20 3.05 3.05 CD cord-254436-89zf41xr 24 21 ( ( -LRB- cord-254436-89zf41xr 24 22 95 95 CD cord-254436-89zf41xr 24 23 % % NN cord-254436-89zf41xr 24 24 CI ci NN cord-254436-89zf41xr 24 25 : : : cord-254436-89zf41xr 24 26 1.57 1.57 CD cord-254436-89zf41xr 24 27 - - SYM cord-254436-89zf41xr 24 28 5.92 5.92 CD cord-254436-89zf41xr 24 29 ) ) -RRB- cord-254436-89zf41xr 24 30 ] ] -RRB- cord-254436-89zf41xr 25 1 in in IN cord-254436-89zf41xr 25 2 a a DT cord-254436-89zf41xr 25 3 meta meta JJ cord-254436-89zf41xr 25 4 - - HYPH cord-254436-89zf41xr 25 5 analysis analysis NN cord-254436-89zf41xr 25 6 of of IN cord-254436-89zf41xr 25 7 over over IN cord-254436-89zf41xr 25 8 40,000 40,000 CD cord-254436-89zf41xr 25 9 confirmed confirm VBN cord-254436-89zf41xr 25 10 COVID19 covid19 IN cord-254436-89zf41xr 25 11 patients patient NNS cord-254436-89zf41xr 25 12 in in IN cord-254436-89zf41xr 25 13 China China NNP cord-254436-89zf41xr 25 14 [ [ -LRB- cord-254436-89zf41xr 25 15 6 6 CD cord-254436-89zf41xr 25 16 ] ] -RRB- cord-254436-89zf41xr 25 17 . . . cord-254436-89zf41xr 26 1 In in IN cord-254436-89zf41xr 26 2 the the DT cord-254436-89zf41xr 26 3 same same JJ cord-254436-89zf41xr 26 4 report report NN cord-254436-89zf41xr 26 5 , , , cord-254436-89zf41xr 26 6 cardiovascular cardiovascular JJ cord-254436-89zf41xr 26 7 disease disease NN cord-254436-89zf41xr 26 8 [ [ -LRB- cord-254436-89zf41xr 26 9 CVD CVD NNP cord-254436-89zf41xr 26 10 ] ] -RRB- cord-254436-89zf41xr 26 11 was be VBD cord-254436-89zf41xr 26 12 associated associate VBN cord-254436-89zf41xr 26 13 with with IN cord-254436-89zf41xr 26 14 a a DT cord-254436-89zf41xr 26 15 5-fold 5-fold CD cord-254436-89zf41xr 26 16 increase increase NN cord-254436-89zf41xr 26 17 in in IN cord-254436-89zf41xr 26 18 risk risk NN cord-254436-89zf41xr 26 19 of of IN cord-254436-89zf41xr 26 20 death death NN cord-254436-89zf41xr 26 21 from from IN cord-254436-89zf41xr 26 22 COVID-19 COVID-19 NNP cord-254436-89zf41xr 26 23 [ [ -LRB- cord-254436-89zf41xr 26 24 6 6 CD cord-254436-89zf41xr 26 25 ] ] -RRB- cord-254436-89zf41xr 26 26 . . . cord-254436-89zf41xr 27 1 Although although IN cord-254436-89zf41xr 27 2 the the DT cord-254436-89zf41xr 27 3 elderly elderly JJ cord-254436-89zf41xr 27 4 are be VBP cord-254436-89zf41xr 27 5 at at IN cord-254436-89zf41xr 27 6 greater great JJR cord-254436-89zf41xr 27 7 risk risk NN cord-254436-89zf41xr 27 8 of of IN cord-254436-89zf41xr 27 9 infection infection NN cord-254436-89zf41xr 27 10 and and CC cord-254436-89zf41xr 27 11 death death NN cord-254436-89zf41xr 27 12 , , , cord-254436-89zf41xr 27 13 younger young JJR cord-254436-89zf41xr 27 14 adults adult NNS cord-254436-89zf41xr 27 15 are be VBP cord-254436-89zf41xr 27 16 also also RB cord-254436-89zf41xr 27 17 at at IN cord-254436-89zf41xr 27 18 risk risk NN cord-254436-89zf41xr 27 19 , , , cord-254436-89zf41xr 27 20 especially especially RB cord-254436-89zf41xr 27 21 those those DT cord-254436-89zf41xr 27 22 who who WP cord-254436-89zf41xr 27 23 are be VBP cord-254436-89zf41xr 27 24 obese obese JJ cord-254436-89zf41xr 27 25 [ [ -LRB- cord-254436-89zf41xr 27 26 8 8 CD cord-254436-89zf41xr 27 27 ] ] -RRB- cord-254436-89zf41xr 28 1 and/or and/or CC cord-254436-89zf41xr 28 2 from from IN cord-254436-89zf41xr 28 3 Black black JJ cord-254436-89zf41xr 28 4 and and CC cord-254436-89zf41xr 28 5 Asian asian JJ cord-254436-89zf41xr 28 6 ethnic ethnic JJ cord-254436-89zf41xr 28 7 minorities minority NNS cord-254436-89zf41xr 28 8 [ [ -LRB- cord-254436-89zf41xr 28 9 9 9 CD cord-254436-89zf41xr 28 10 ] ] -RRB- cord-254436-89zf41xr 28 11 . . . cord-254436-89zf41xr 29 1 A a DT cord-254436-89zf41xr 29 2 recent recent JJ cord-254436-89zf41xr 29 3 meta meta JJ cord-254436-89zf41xr 29 4 - - HYPH cord-254436-89zf41xr 29 5 analysis analysis NN cord-254436-89zf41xr 29 6 of of IN cord-254436-89zf41xr 29 7 almost almost RB cord-254436-89zf41xr 29 8 400,000 400,000 CD cord-254436-89zf41xr 29 9 subjects subject NNS cord-254436-89zf41xr 29 10 [ [ -LRB- cord-254436-89zf41xr 29 11 8 8 CD cord-254436-89zf41xr 29 12 ] ] -RRB- cord-254436-89zf41xr 29 13 reported report VBD cord-254436-89zf41xr 29 14 that that IN cord-254436-89zf41xr 29 15 patients patient NNS cord-254436-89zf41xr 29 16 with with IN cord-254436-89zf41xr 29 17 a a DT cord-254436-89zf41xr 29 18 BMI BMI NNP cord-254436-89zf41xr 29 19 over over IN cord-254436-89zf41xr 29 20 30 30 CD cord-254436-89zf41xr 29 21 kg kg NN cord-254436-89zf41xr 29 22 / / SYM cord-254436-89zf41xr 29 23 m m NN cord-254436-89zf41xr 29 24 2 2 CD cord-254436-89zf41xr 29 25 were be VBD cord-254436-89zf41xr 29 26 ~50 ~50 NFP cord-254436-89zf41xr 29 27 % % NN cord-254436-89zf41xr 29 28 more more RBR cord-254436-89zf41xr 29 29 likely likely JJ cord-254436-89zf41xr 29 30 to to TO cord-254436-89zf41xr 29 31 develop develop VB cord-254436-89zf41xr 30 1 COVID-19and covid-19and NN cord-254436-89zf41xr 30 2 for for IN cord-254436-89zf41xr 30 3 those those DT cord-254436-89zf41xr 30 4 with with IN cord-254436-89zf41xr 30 5 COVID-19 COVID-19 NNP cord-254436-89zf41xr 30 6 , , , cord-254436-89zf41xr 30 7 over over RB cord-254436-89zf41xr 30 8 twice twice RB cord-254436-89zf41xr 30 9 as as RB cord-254436-89zf41xr 30 10 likely likely JJ cord-254436-89zf41xr 30 11 to to TO cord-254436-89zf41xr 30 12 be be VB cord-254436-89zf41xr 30 13 admitted admit VBN cord-254436-89zf41xr 30 14 to to IN cord-254436-89zf41xr 30 15 hospital hospital NN cord-254436-89zf41xr 30 16 for for IN cord-254436-89zf41xr 30 17 treatment treatment NN cord-254436-89zf41xr 30 18 , , , cord-254436-89zf41xr 30 19 ~75 ~75 NFP cord-254436-89zf41xr 30 20 % % NN cord-254436-89zf41xr 30 21 more more RBR cord-254436-89zf41xr 30 22 likely likely JJ cord-254436-89zf41xr 30 23 to to TO cord-254436-89zf41xr 30 24 be be VB cord-254436-89zf41xr 30 25 admitted admit VBN cord-254436-89zf41xr 30 26 to to IN cord-254436-89zf41xr 30 27 an an DT cord-254436-89zf41xr 30 28 Intensive Intensive NNP cord-254436-89zf41xr 30 29 Care Care NNP cord-254436-89zf41xr 30 30 Unit Unit NNP cord-254436-89zf41xr 30 31 and and CC cord-254436-89zf41xr 30 32 had have VBD cord-254436-89zf41xr 30 33 a a DT cord-254436-89zf41xr 30 34 ~50 ~50 CD cord-254436-89zf41xr 30 35 % % NN cord-254436-89zf41xr 30 36 greater great JJR cord-254436-89zf41xr 30 37 mortality mortality NN cord-254436-89zf41xr 30 38 than than IN cord-254436-89zf41xr 30 39 the the DT cord-254436-89zf41xr 30 40 less less RBR cord-254436-89zf41xr 30 41 overweight overweight JJ cord-254436-89zf41xr 30 42 . . . cord-254436-89zf41xr 31 1 For for IN cord-254436-89zf41xr 31 2 patients patient NNS cord-254436-89zf41xr 31 3 from from IN cord-254436-89zf41xr 31 4 BAME BAME NNP cord-254436-89zf41xr 31 5 groups group NNS cord-254436-89zf41xr 31 6 , , , cord-254436-89zf41xr 31 7 a a DT cord-254436-89zf41xr 31 8 lower low JJR cord-254436-89zf41xr 31 9 BMI bmi NN cord-254436-89zf41xr 31 10 threshold threshold NN cord-254436-89zf41xr 31 11 of of IN cord-254436-89zf41xr 31 12 over over IN cord-254436-89zf41xr 31 13 25 25 CD cord-254436-89zf41xr 31 14 kg kg NNS cord-254436-89zf41xr 31 15 / / SYM cord-254436-89zf41xr 31 16 m m NN cord-254436-89zf41xr 31 17 2 2 CD cord-254436-89zf41xr 31 18 appeared appear VBD cord-254436-89zf41xr 31 19 associated associate VBN cord-254436-89zf41xr 31 20 with with IN cord-254436-89zf41xr 31 21 worse bad JJR cord-254436-89zf41xr 31 22 severity severity NN cord-254436-89zf41xr 31 23 from from IN cord-254436-89zf41xr 31 24 COVID-19 COVID-19 NNP cord-254436-89zf41xr 31 25 . . . cord-254436-89zf41xr 32 1 In in IN cord-254436-89zf41xr 32 2 addition addition NN cord-254436-89zf41xr 32 3 to to IN cord-254436-89zf41xr 32 4 being be VBG cord-254436-89zf41xr 32 5 at at IN cord-254436-89zf41xr 32 6 increased increase VBN cord-254436-89zf41xr 32 7 risk risk NN cord-254436-89zf41xr 32 8 of of IN cord-254436-89zf41xr 32 9 COVID-19 COVID-19 NNP cord-254436-89zf41xr 32 10 , , , cord-254436-89zf41xr 32 11 obese obese JJ cord-254436-89zf41xr 32 12 patients patient NNS cord-254436-89zf41xr 32 13 also also RB cord-254436-89zf41xr 32 14 appear appear VBP cord-254436-89zf41xr 32 15 less less RBR cord-254436-89zf41xr 32 16 likely likely JJ cord-254436-89zf41xr 32 17 to to TO cord-254436-89zf41xr 32 18 respond respond VB cord-254436-89zf41xr 32 19 effectively effectively RB cord-254436-89zf41xr 32 20 to to IN cord-254436-89zf41xr 32 21 the the DT cord-254436-89zf41xr 32 22 influenza influenza NN cord-254436-89zf41xr 32 23 immunization immunization NN cord-254436-89zf41xr 32 24 [ [ -LRB- cord-254436-89zf41xr 32 25 10 10 CD cord-254436-89zf41xr 32 26 ] ] -RRB- cord-254436-89zf41xr 32 27 . . . cord-254436-89zf41xr 33 1 There there EX cord-254436-89zf41xr 33 2 are be VBP cord-254436-89zf41xr 33 3 therefore therefore RB cord-254436-89zf41xr 33 4 concerns concern NNS cord-254436-89zf41xr 33 5 that that IN cord-254436-89zf41xr 33 6 obese obese JJ cord-254436-89zf41xr 33 7 people people NNS cord-254436-89zf41xr 33 8 may may MD cord-254436-89zf41xr 33 9 also also RB cord-254436-89zf41xr 33 10 respond respond VB cord-254436-89zf41xr 33 11 less less RBR cord-254436-89zf41xr 33 12 well well RB cord-254436-89zf41xr 33 13 to to IN cord-254436-89zf41xr 33 14 immunization immunization NN cord-254436-89zf41xr 33 15 against against IN cord-254436-89zf41xr 33 16 SARS SARS NNP cord-254436-89zf41xr 33 17 - - HYPH cord-254436-89zf41xr 33 18 CoV2 CoV2 NNP cord-254436-89zf41xr 33 19 . . . cord-254436-89zf41xr 34 1 However however RB cord-254436-89zf41xr 34 2 , , , cord-254436-89zf41xr 34 3 as as IN cord-254436-89zf41xr 34 4 an an DT cord-254436-89zf41xr 34 5 example example NN cord-254436-89zf41xr 34 6 of of IN cord-254436-89zf41xr 34 7 the the DT cord-254436-89zf41xr 34 8 global global JJ cord-254436-89zf41xr 34 9 health health NN cord-254436-89zf41xr 34 10 challenge challenge NN cord-254436-89zf41xr 34 11 , , , cord-254436-89zf41xr 34 12 despite despite IN cord-254436-89zf41xr 34 13 international international JJ cord-254436-89zf41xr 34 14 efforts effort NNS cord-254436-89zf41xr 34 15 , , , cord-254436-89zf41xr 34 16 including include VBG cord-254436-89zf41xr 34 17 Sustainable Sustainable NNP cord-254436-89zf41xr 34 18 Development Development NNP cord-254436-89zf41xr 34 19 Goals Goals NNPS cord-254436-89zf41xr 34 20 for for IN cord-254436-89zf41xr 34 21 health health NN cord-254436-89zf41xr 34 22 adopted adopt VBN cord-254436-89zf41xr 34 23 by by IN cord-254436-89zf41xr 34 24 G20 G20 NNP cord-254436-89zf41xr 34 25 countries country NNS cord-254436-89zf41xr 34 26 [ [ -LRB- cord-254436-89zf41xr 34 27 11 11 CD cord-254436-89zf41xr 34 28 ] ] -RRB- cord-254436-89zf41xr 34 29 , , , cord-254436-89zf41xr 34 30 obesity obesity NN cord-254436-89zf41xr 34 31 remains remain VBZ cord-254436-89zf41xr 34 32 an an DT cord-254436-89zf41xr 34 33 international international JJ cord-254436-89zf41xr 34 34 epidemic epidemic NN cord-254436-89zf41xr 34 35 , , , cord-254436-89zf41xr 34 36 despite despite IN cord-254436-89zf41xr 34 37 its -PRON- PRP$ cord-254436-89zf41xr 34 38 being be VBG cord-254436-89zf41xr 34 39 recognized recognize VBN cord-254436-89zf41xr 34 40 as as IN cord-254436-89zf41xr 34 41 a a DT cord-254436-89zf41xr 34 42 disease disease NN cord-254436-89zf41xr 34 43 by by IN cord-254436-89zf41xr 34 44 many many JJ cord-254436-89zf41xr 34 45 organisations organisation NNS cord-254436-89zf41xr 34 46 [ [ -LRB- cord-254436-89zf41xr 34 47 12 12 CD cord-254436-89zf41xr 34 48 ] ] -RRB- cord-254436-89zf41xr 34 49 including include VBG cord-254436-89zf41xr 34 50 by by IN cord-254436-89zf41xr 34 51 the the DT cord-254436-89zf41xr 34 52 American American NNP cord-254436-89zf41xr 34 53 Medical Medical NNP cord-254436-89zf41xr 34 54 Association Association NNP cord-254436-89zf41xr 34 55 since since IN cord-254436-89zf41xr 34 56 2013 2013 CD cord-254436-89zf41xr 34 57 , , , cord-254436-89zf41xr 34 58 and and CC cord-254436-89zf41xr 34 59 the the DT cord-254436-89zf41xr 34 60 long long RB cord-254436-89zf41xr 34 61 - - HYPH cord-254436-89zf41xr 34 62 established establish VBN cord-254436-89zf41xr 34 63 role role NN cord-254436-89zf41xr 34 64 of of IN cord-254436-89zf41xr 34 65 obesity obesity NN cord-254436-89zf41xr 34 66 as as IN cord-254436-89zf41xr 34 67 a a DT cord-254436-89zf41xr 34 68 major major JJ cord-254436-89zf41xr 34 69 contributor contributor NN cord-254436-89zf41xr 34 70 to to IN cord-254436-89zf41xr 34 71 serious serious JJ cord-254436-89zf41xr 34 72 disorders disorder NNS cord-254436-89zf41xr 34 73 of of IN cord-254436-89zf41xr 34 74 the the DT cord-254436-89zf41xr 34 75 heart heart NN cord-254436-89zf41xr 34 76 , , , cord-254436-89zf41xr 34 77 brain brain NN cord-254436-89zf41xr 34 78 and and CC cord-254436-89zf41xr 34 79 circulation circulation NN cord-254436-89zf41xr 34 80 , , , cord-254436-89zf41xr 34 81 as as RB cord-254436-89zf41xr 34 82 well well RB cord-254436-89zf41xr 34 83 as as IN cord-254436-89zf41xr 34 84 many many JJ cord-254436-89zf41xr 34 85 cancers cancer NNS cord-254436-89zf41xr 34 86 , , , cord-254436-89zf41xr 34 87 joint joint JJ cord-254436-89zf41xr 34 88 disease disease NN cord-254436-89zf41xr 34 89 and and CC cord-254436-89zf41xr 34 90 poor poor JJ cord-254436-89zf41xr 34 91 mental mental JJ cord-254436-89zf41xr 34 92 health health NN cord-254436-89zf41xr 34 93 . . . cord-254436-89zf41xr 35 1 The the DT cord-254436-89zf41xr 35 2 WHO who WP cord-254436-89zf41xr 35 3 estimates estimate VBZ cord-254436-89zf41xr 35 4 that that IN cord-254436-89zf41xr 35 5 obesity obesity NN cord-254436-89zf41xr 35 6 has have VBZ cord-254436-89zf41xr 35 7 tripled triple VBN cord-254436-89zf41xr 35 8 since since IN cord-254436-89zf41xr 35 9 1975 1975 CD cord-254436-89zf41xr 35 10 and and CC cord-254436-89zf41xr 35 11 that that IN cord-254436-89zf41xr 35 12 by by IN cord-254436-89zf41xr 35 13 2016 2016 CD cord-254436-89zf41xr 35 14 there there EX cord-254436-89zf41xr 35 15 were be VBD cord-254436-89zf41xr 35 16 650 650 CD cord-254436-89zf41xr 35 17 million million CD cord-254436-89zf41xr 35 18 obese obese JJ cord-254436-89zf41xr 35 19 people people NNS cord-254436-89zf41xr 35 20 globally globally RB cord-254436-89zf41xr 35 21 ( ( -LRB- cord-254436-89zf41xr 35 22 1.6 1.6 CD cord-254436-89zf41xr 35 23 billion billion CD cord-254436-89zf41xr 35 24 overweight overweight NN cord-254436-89zf41xr 35 25 ) ) -RRB- cord-254436-89zf41xr 36 1 [ [ -LRB- cord-254436-89zf41xr 36 2 13 13 CD cord-254436-89zf41xr 36 3 ] ] -RRB- cord-254436-89zf41xr 36 4 . . . cord-254436-89zf41xr 37 1 Reasons reason NNS cord-254436-89zf41xr 37 2 why why WRB cord-254436-89zf41xr 37 3 Black black JJ cord-254436-89zf41xr 37 4 and and CC cord-254436-89zf41xr 37 5 Ethnic ethnic JJ cord-254436-89zf41xr 37 6 minorities minority NNS cord-254436-89zf41xr 37 7 ( ( -LRB- cord-254436-89zf41xr 37 8 BAME BAME NNP cord-254436-89zf41xr 37 9 ) ) -RRB- cord-254436-89zf41xr 37 10 are be VBP cord-254436-89zf41xr 37 11 more more JJR cord-254436-89zf41xr 37 12 at at IN cord-254436-89zf41xr 37 13 risk risk NN cord-254436-89zf41xr 37 14 of of IN cord-254436-89zf41xr 37 15 infection infection NN cord-254436-89zf41xr 37 16 with with IN cord-254436-89zf41xr 37 17 SARS SARS NNP cord-254436-89zf41xr 37 18 - - HYPH cord-254436-89zf41xr 37 19 CoV2 CoV2 NNP cord-254436-89zf41xr 37 20 and and CC cord-254436-89zf41xr 37 21 of of IN cord-254436-89zf41xr 37 22 worse bad JJR cord-254436-89zf41xr 37 23 outcomes outcome NNS cord-254436-89zf41xr 37 24 from from IN cord-254436-89zf41xr 37 25 COVID-19 COVID-19 NNP cord-254436-89zf41xr 37 26 are be VBP cord-254436-89zf41xr 37 27 unclear unclear JJ cord-254436-89zf41xr 37 28 [ [ -LRB- cord-254436-89zf41xr 37 29 8 8 CD cord-254436-89zf41xr 37 30 ] ] -RRB- cord-254436-89zf41xr 37 31 . . . cord-254436-89zf41xr 38 1 For for IN cord-254436-89zf41xr 38 2 example example NN cord-254436-89zf41xr 38 3 , , , cord-254436-89zf41xr 38 4 in in IN cord-254436-89zf41xr 38 5 one one CD cord-254436-89zf41xr 38 6 study study NN cord-254436-89zf41xr 38 7 in in IN cord-254436-89zf41xr 38 8 the the DT cord-254436-89zf41xr 38 9 UK UK NNP cord-254436-89zf41xr 38 10 , , , cord-254436-89zf41xr 38 11 one one CD cord-254436-89zf41xr 38 12 third third NN cord-254436-89zf41xr 38 13 of of IN cord-254436-89zf41xr 38 14 patients patient NNS cord-254436-89zf41xr 38 15 admitted admit VBN cord-254436-89zf41xr 38 16 to to IN cord-254436-89zf41xr 38 17 ICU ICU NNP cord-254436-89zf41xr 38 18 due due IN cord-254436-89zf41xr 38 19 to to IN cord-254436-89zf41xr 38 20 COVID-19 COVID-19 NNP cord-254436-89zf41xr 38 21 were be VBD cord-254436-89zf41xr 38 22 from from IN cord-254436-89zf41xr 38 23 an an DT cord-254436-89zf41xr 38 24 ethnic ethnic JJ cord-254436-89zf41xr 38 25 minority minority NN cord-254436-89zf41xr 38 26 [ [ -LRB- cord-254436-89zf41xr 38 27 14 14 CD cord-254436-89zf41xr 38 28 ] ] -RRB- cord-254436-89zf41xr 38 29 with with IN cord-254436-89zf41xr 38 30 similar similar JJ cord-254436-89zf41xr 38 31 reports report NNS cord-254436-89zf41xr 38 32 from from IN cord-254436-89zf41xr 38 33 the the DT cord-254436-89zf41xr 38 34 USA USA NNP cord-254436-89zf41xr 38 35 . . . cord-254436-89zf41xr 39 1 Possible possible JJ cord-254436-89zf41xr 39 2 reasons reason NNS cord-254436-89zf41xr 39 3 include include VBP cord-254436-89zf41xr 39 4 a a DT cord-254436-89zf41xr 39 5 higher high JJR cord-254436-89zf41xr 39 6 prevalence prevalence NN cord-254436-89zf41xr 39 7 in in IN cord-254436-89zf41xr 39 8 BAME BAME NNP cord-254436-89zf41xr 39 9 populations population NNS cord-254436-89zf41xr 39 10 of of IN cord-254436-89zf41xr 39 11 cardiovascular cardiovascular JJ cord-254436-89zf41xr 39 12 risk risk NN cord-254436-89zf41xr 39 13 factors factor NNS cord-254436-89zf41xr 39 14 e.g. e.g. IN cord-254436-89zf41xr 39 15 hypertension hypertension NN cord-254436-89zf41xr 39 16 , , , cord-254436-89zf41xr 39 17 diabetes diabetes NN cord-254436-89zf41xr 39 18 mellitus mellitus NN cord-254436-89zf41xr 39 19 , , , cord-254436-89zf41xr 39 20 insulin insulin NN cord-254436-89zf41xr 39 21 resistance resistance NN cord-254436-89zf41xr 39 22 and and CC cord-254436-89zf41xr 39 23 obesity obesity NN cord-254436-89zf41xr 39 24 , , , cord-254436-89zf41xr 39 25 socioeconomic socioeconomic JJ cord-254436-89zf41xr 39 26 , , , cord-254436-89zf41xr 39 27 cultural cultural JJ cord-254436-89zf41xr 39 28 , , , cord-254436-89zf41xr 39 29 or or CC cord-254436-89zf41xr 39 30 lifestyle lifestyle NN cord-254436-89zf41xr 39 31 factors factor NNS cord-254436-89zf41xr 39 32 and and CC cord-254436-89zf41xr 39 33 genetic genetic JJ cord-254436-89zf41xr 39 34 predisposition predisposition NN cord-254436-89zf41xr 39 35 . . . cord-254436-89zf41xr 40 1 There there EX cord-254436-89zf41xr 40 2 may may MD cord-254436-89zf41xr 40 3 also also RB cord-254436-89zf41xr 40 4 be be VB cord-254436-89zf41xr 40 5 pathophysiological pathophysiological JJ cord-254436-89zf41xr 40 6 differences difference NNS cord-254436-89zf41xr 40 7 in in IN cord-254436-89zf41xr 40 8 susceptibility susceptibility NN cord-254436-89zf41xr 40 9 or or CC cord-254436-89zf41xr 40 10 response response NN cord-254436-89zf41xr 40 11 to to IN cord-254436-89zf41xr 40 12 infection infection NN cord-254436-89zf41xr 40 13 due due JJ cord-254436-89zf41xr 40 14 for for IN cord-254436-89zf41xr 40 15 example example NN cord-254436-89zf41xr 40 16 to to IN cord-254436-89zf41xr 40 17 increased increase VBN cord-254436-89zf41xr 40 18 prevalence prevalence NN cord-254436-89zf41xr 40 19 of of IN cord-254436-89zf41xr 40 20 vitamin vitamin NN cord-254436-89zf41xr 40 21 D d NN cord-254436-89zf41xr 40 22 deficiency deficiency NN cord-254436-89zf41xr 40 23 . . . cord-254436-89zf41xr 41 1 An an DT cord-254436-89zf41xr 41 2 increased increase VBN cord-254436-89zf41xr 41 3 inflammatory inflammatory JJ cord-254436-89zf41xr 41 4 burden burden NN cord-254436-89zf41xr 41 5 may may MD cord-254436-89zf41xr 41 6 also also RB cord-254436-89zf41xr 41 7 contribute contribute VB cord-254436-89zf41xr 41 8 to to IN cord-254436-89zf41xr 41 9 worse bad JJR cord-254436-89zf41xr 41 10 outcomes outcome NNS cord-254436-89zf41xr 41 11 . . . cord-254436-89zf41xr 42 1 ACE-2 ACE-2 NNP cord-254436-89zf41xr 43 1 ( ( -LRB- cord-254436-89zf41xr 43 2 angiotensin angiotensin NN cord-254436-89zf41xr 43 3 converting convert VBG cord-254436-89zf41xr 43 4 enzyme enzyme NN cord-254436-89zf41xr 43 5 II II NNP cord-254436-89zf41xr 43 6 ) ) -RRB- cord-254436-89zf41xr 43 7 is be VBZ cord-254436-89zf41xr 43 8 the the DT cord-254436-89zf41xr 43 9 key key JJ cord-254436-89zf41xr 43 10 docking docking NN cord-254436-89zf41xr 43 11 protein protein NN cord-254436-89zf41xr 43 12 by by IN cord-254436-89zf41xr 43 13 which which WDT cord-254436-89zf41xr 43 14 the the DT cord-254436-89zf41xr 43 15 COVID-19 COVID-19 NNP cord-254436-89zf41xr 43 16 virus virus NN cord-254436-89zf41xr 43 17 binds bind VBZ cord-254436-89zf41xr 43 18 to to IN cord-254436-89zf41xr 43 19 cells cell NNS cord-254436-89zf41xr 43 20 [ [ -LRB- cord-254436-89zf41xr 43 21 15 15 CD cord-254436-89zf41xr 43 22 ] ] -RRB- cord-254436-89zf41xr 43 23 . . . cord-254436-89zf41xr 44 1 This this DT cord-254436-89zf41xr 44 2 is be VBZ cord-254436-89zf41xr 44 3 also also RB cord-254436-89zf41xr 44 4 the the DT cord-254436-89zf41xr 44 5 key key JJ cord-254436-89zf41xr 44 6 cell cell NN cord-254436-89zf41xr 44 7 entry entry NN cord-254436-89zf41xr 44 8 receptor receptor NN cord-254436-89zf41xr 44 9 used use VBN cord-254436-89zf41xr 44 10 by by IN cord-254436-89zf41xr 44 11 the the DT cord-254436-89zf41xr 44 12 initial initial JJ cord-254436-89zf41xr 44 13 SARS SARS NNP cord-254436-89zf41xr 44 14 - - HYPH cord-254436-89zf41xr 44 15 CoV CoV NNP cord-254436-89zf41xr 44 16 [ [ -LRB- cord-254436-89zf41xr 44 17 14 14 CD cord-254436-89zf41xr 44 18 ] ] -RRB- cord-254436-89zf41xr 44 19 . . . cord-254436-89zf41xr 45 1 ACE-2 ACE-2 NNP cord-254436-89zf41xr 45 2 is be VBZ cord-254436-89zf41xr 45 3 mainly mainly RB cord-254436-89zf41xr 45 4 found find VBN cord-254436-89zf41xr 45 5 on on IN cord-254436-89zf41xr 45 6 vascular vascular JJ cord-254436-89zf41xr 45 7 endothelial endothelial JJ cord-254436-89zf41xr 45 8 cells cell NNS cord-254436-89zf41xr 45 9 , , , cord-254436-89zf41xr 45 10 the the DT cord-254436-89zf41xr 45 11 renal renal JJ cord-254436-89zf41xr 45 12 tubular tubular JJ cord-254436-89zf41xr 45 13 epithelium epithelium NN cord-254436-89zf41xr 45 14 and and CC cord-254436-89zf41xr 45 15 the the DT cord-254436-89zf41xr 45 16 Leydig Leydig NNP cord-254436-89zf41xr 45 17 cells cell NNS cord-254436-89zf41xr 45 18 of of IN cord-254436-89zf41xr 45 19 the the DT cord-254436-89zf41xr 45 20 testis testis NN cord-254436-89zf41xr 45 21 . . . cord-254436-89zf41xr 46 1 Copies copy NNS cord-254436-89zf41xr 46 2 of of IN cord-254436-89zf41xr 46 3 the the DT cord-254436-89zf41xr 46 4 ACE-2 ACE-2 NNP cord-254436-89zf41xr 46 5 protein protein NN cord-254436-89zf41xr 46 6 are be VBP cord-254436-89zf41xr 46 7 present present JJ cord-254436-89zf41xr 46 8 in in IN cord-254436-89zf41xr 46 9 increased increase VBN cord-254436-89zf41xr 46 10 numbers number NNS cord-254436-89zf41xr 46 11 in in IN cord-254436-89zf41xr 46 12 patients patient NNS cord-254436-89zf41xr 46 13 with with IN cord-254436-89zf41xr 46 14 risk risk NN cord-254436-89zf41xr 46 15 factors factor NNS cord-254436-89zf41xr 46 16 for for IN cord-254436-89zf41xr 46 17 heart heart NN cord-254436-89zf41xr 46 18 disease disease NN cord-254436-89zf41xr 46 19 . . . cord-254436-89zf41xr 47 1 ACE-2 ACE-2 NNP cord-254436-89zf41xr 47 2 could could MD cord-254436-89zf41xr 47 3 thus thus RB cord-254436-89zf41xr 47 4 be be VB cord-254436-89zf41xr 47 5 a a DT cord-254436-89zf41xr 47 6 therapeutic therapeutic JJ cord-254436-89zf41xr 47 7 target target NN cord-254436-89zf41xr 47 8 in in IN cord-254436-89zf41xr 47 9 the the DT cord-254436-89zf41xr 47 10 treatment treatment NN cord-254436-89zf41xr 47 11 of of IN cord-254436-89zf41xr 47 12 COVID-19 COVID-19 NNP cord-254436-89zf41xr 47 13 . . . cord-254436-89zf41xr 48 1 However however RB cord-254436-89zf41xr 48 2 enzymatic enzymatic JJ cord-254436-89zf41xr 48 3 activity activity NN cord-254436-89zf41xr 48 4 of of IN cord-254436-89zf41xr 48 5 ACE2 ACE2 NNP cord-254436-89zf41xr 48 6 controls control VBZ cord-254436-89zf41xr 48 7 activation activation NN cord-254436-89zf41xr 48 8 of of IN cord-254436-89zf41xr 48 9 the the DT cord-254436-89zf41xr 48 10 renin renin NN cord-254436-89zf41xr 48 11 - - HYPH cord-254436-89zf41xr 48 12 angiotensin angiotensin NN cord-254436-89zf41xr 48 13 - - HYPH cord-254436-89zf41xr 48 14 aldosterone aldosterone NN cord-254436-89zf41xr 48 15 system system NN cord-254436-89zf41xr 48 16 ( ( -LRB- cord-254436-89zf41xr 48 17 RAAS RAAS NNP cord-254436-89zf41xr 48 18 ) ) -RRB- cord-254436-89zf41xr 48 19 , , , cord-254436-89zf41xr 48 20 a a DT cord-254436-89zf41xr 48 21 current current JJ cord-254436-89zf41xr 48 22 therapeutic therapeutic JJ cord-254436-89zf41xr 48 23 target target NN cord-254436-89zf41xr 48 24 in in IN cord-254436-89zf41xr 48 25 cardiovascular cardiovascular JJ cord-254436-89zf41xr 48 26 and and CC cord-254436-89zf41xr 48 27 renal renal JJ cord-254436-89zf41xr 48 28 disease disease NN cord-254436-89zf41xr 48 29 . . . cord-254436-89zf41xr 49 1 There there EX cord-254436-89zf41xr 49 2 were be VBD cord-254436-89zf41xr 49 3 concerns concern NNS cord-254436-89zf41xr 49 4 that that IN cord-254436-89zf41xr 49 5 common common JJ cord-254436-89zf41xr 49 6 medicines medicine NNS cord-254436-89zf41xr 49 7 such such JJ cord-254436-89zf41xr 49 8 as as IN cord-254436-89zf41xr 49 9 ACE ace NN cord-254436-89zf41xr 49 10 inhibitors inhibitor NNS cord-254436-89zf41xr 49 11 ( ( -LRB- cord-254436-89zf41xr 49 12 ACEi ACEi NNP cord-254436-89zf41xr 49 13 ) ) -RRB- cord-254436-89zf41xr 49 14 or or CC cord-254436-89zf41xr 49 15 Angiotensin Angiotensin NNP cord-254436-89zf41xr 49 16 Receptor Receptor NNP cord-254436-89zf41xr 49 17 Blockers Blockers NNP cord-254436-89zf41xr 49 18 ( ( -LRB- cord-254436-89zf41xr 49 19 ARBs arb NNS cord-254436-89zf41xr 49 20 ) ) -RRB- cord-254436-89zf41xr 49 21 used use VBD cord-254436-89zf41xr 49 22 to to TO cord-254436-89zf41xr 49 23 treat treat VB cord-254436-89zf41xr 49 24 hypertension hypertension NN cord-254436-89zf41xr 49 25 or or CC cord-254436-89zf41xr 49 26 heart heart NN cord-254436-89zf41xr 49 27 failure failure NN cord-254436-89zf41xr 49 28 by by IN cord-254436-89zf41xr 49 29 inhibiting inhibit VBG cord-254436-89zf41xr 49 30 the the DT cord-254436-89zf41xr 49 31 renin renin NN cord-254436-89zf41xr 49 32 - - HYPH cord-254436-89zf41xr 49 33 angiotensin angiotensin NN cord-254436-89zf41xr 49 34 system system NN cord-254436-89zf41xr 49 35 could could MD cord-254436-89zf41xr 49 36 adversely adversely RB cord-254436-89zf41xr 49 37 affect affect VB cord-254436-89zf41xr 49 38 ACE2 ACE2 NNP cord-254436-89zf41xr 49 39 expression expression NN cord-254436-89zf41xr 49 40 . . . cord-254436-89zf41xr 50 1 However however RB cord-254436-89zf41xr 50 2 , , , cord-254436-89zf41xr 50 3 studies study NNS cord-254436-89zf41xr 50 4 to to IN cord-254436-89zf41xr 50 5 date date NN cord-254436-89zf41xr 50 6 in in IN cord-254436-89zf41xr 50 7 SARS SARS NNP cord-254436-89zf41xr 50 8 - - HYPH cord-254436-89zf41xr 50 9 CoV-2-infected cov-2-infecte VBN cord-254436-89zf41xr 50 10 patients patient NNS cord-254436-89zf41xr 50 11 do do VBP cord-254436-89zf41xr 50 12 not not RB cord-254436-89zf41xr 50 13 suggest suggest VB cord-254436-89zf41xr 50 14 that that IN cord-254436-89zf41xr 50 15 these these DT cord-254436-89zf41xr 50 16 RAAS raa NNS cord-254436-89zf41xr 50 17 modulators modulator NNS cord-254436-89zf41xr 50 18 influence influence VBP cord-254436-89zf41xr 50 19 susceptibility susceptibility NN cord-254436-89zf41xr 50 20 to to IN cord-254436-89zf41xr 50 21 the the DT cord-254436-89zf41xr 50 22 infection infection NN cord-254436-89zf41xr 50 23 or or CC cord-254436-89zf41xr 50 24 cause cause VB cord-254436-89zf41xr 50 25 more more RBR cord-254436-89zf41xr 50 26 severe severe JJ cord-254436-89zf41xr 50 27 COVID-19 covid-19 NN cord-254436-89zf41xr 50 28 . . . cord-254436-89zf41xr 51 1 Indeed indeed RB cord-254436-89zf41xr 51 2 , , , cord-254436-89zf41xr 51 3 in in IN cord-254436-89zf41xr 51 4 a a DT cord-254436-89zf41xr 51 5 meta meta JJ cord-254436-89zf41xr 51 6 - - HYPH cord-254436-89zf41xr 51 7 analysis analysis NN cord-254436-89zf41xr 51 8 of of IN cord-254436-89zf41xr 51 9 almost almost RB cord-254436-89zf41xr 51 10 29,000 29,000 CD cord-254436-89zf41xr 51 11 patients patient NNS cord-254436-89zf41xr 51 12 with with IN cord-254436-89zf41xr 51 13 COVID-19 COVID-19 NNP cord-254436-89zf41xr 51 14 , , , cord-254436-89zf41xr 51 15 use use NN cord-254436-89zf41xr 51 16 of of IN cord-254436-89zf41xr 51 17 RAAS RAAS NNP cord-254436-89zf41xr 51 18 inhibitors inhibitor NNS cord-254436-89zf41xr 51 19 for for IN cord-254436-89zf41xr 51 20 any any DT cord-254436-89zf41xr 51 21 conditions condition NNS cord-254436-89zf41xr 51 22 showed show VBD cord-254436-89zf41xr 51 23 a a DT cord-254436-89zf41xr 51 24 trend trend NN cord-254436-89zf41xr 51 25 to to TO cord-254436-89zf41xr 51 26 lower low JJR cord-254436-89zf41xr 51 27 risk risk NN cord-254436-89zf41xr 51 28 of of IN cord-254436-89zf41xr 51 29 death death NN cord-254436-89zf41xr 51 30 or or CC cord-254436-89zf41xr 51 31 critical critical JJ cord-254436-89zf41xr 51 32 events event NNS cord-254436-89zf41xr 51 33 ( ( -LRB- cord-254436-89zf41xr 51 34 odds odd NNS cord-254436-89zf41xr 51 35 ratio ratio NN cord-254436-89zf41xr 51 36 0.67 0.67 CD cord-254436-89zf41xr 51 37 , , , cord-254436-89zf41xr 51 38 95 95 CD cord-254436-89zf41xr 51 39 % % NN cord-254436-89zf41xr 51 40 CI CI NNP cord-254436-89zf41xr 51 41 0.43 0.43 CD cord-254436-89zf41xr 51 42 to to IN cord-254436-89zf41xr 51 43 1.03 1.03 CD cord-254436-89zf41xr 51 44 , , , cord-254436-89zf41xr 51 45 p p NN cord-254436-89zf41xr 51 46 = = SYM cord-254436-89zf41xr 51 47 0.07 0.07 CD cord-254436-89zf41xr 51 48 ) ) -RRB- cord-254436-89zf41xr 51 49 . . . cord-254436-89zf41xr 52 1 Within within IN cord-254436-89zf41xr 52 2 the the DT cord-254436-89zf41xr 52 3 hypertensive hypertensive JJ cord-254436-89zf41xr 52 4 cohort cohort NN cord-254436-89zf41xr 52 5 , , , cord-254436-89zf41xr 52 6 treatment treatment NN cord-254436-89zf41xr 52 7 with with IN cord-254436-89zf41xr 52 8 ACEi ACEi NNS cord-254436-89zf41xr 52 9 or or CC cord-254436-89zf41xr 52 10 ARBs arb NNS cord-254436-89zf41xr 52 11 was be VBD cord-254436-89zf41xr 52 12 associated associate VBN cord-254436-89zf41xr 52 13 with with IN cord-254436-89zf41xr 52 14 one one CD cord-254436-89zf41xr 52 15 third third NN cord-254436-89zf41xr 52 16 less less JJR cord-254436-89zf41xr 52 17 mortality mortality NN cord-254436-89zf41xr 52 18 from from IN cord-254436-89zf41xr 52 19 COVID-19 COVID-19 NNP cord-254436-89zf41xr 52 20 ( ( -LRB- cord-254436-89zf41xr 52 21 odds odd NNS cord-254436-89zf41xr 52 22 ratio ratio NN cord-254436-89zf41xr 52 23 0.66 0.66 CD cord-254436-89zf41xr 52 24 , , , cord-254436-89zf41xr 52 25 CI CI NNP cord-254436-89zf41xr 52 26 0.46 0.46 CD cord-254436-89zf41xr 52 27 to to IN cord-254436-89zf41xr 52 28 0.96 0.96 CD cord-254436-89zf41xr 52 29 , , , cord-254436-89zf41xr 52 30 p p NN cord-254436-89zf41xr 52 31 = = SYM cord-254436-89zf41xr 52 32 0.03 0.03 CD cord-254436-89zf41xr 52 33 ) ) -RRB- cord-254436-89zf41xr 52 34 and and CC cord-254436-89zf41xr 52 35 a a DT cord-254436-89zf41xr 52 36 one one CD cord-254436-89zf41xr 52 37 third third JJ cord-254436-89zf41xr 52 38 reduction reduction NN cord-254436-89zf41xr 52 39 in in IN cord-254436-89zf41xr 52 40 the the DT cord-254436-89zf41xr 52 41 combined combined JJ cord-254436-89zf41xr 52 42 end end NN cord-254436-89zf41xr 52 43 - - HYPH cord-254436-89zf41xr 52 44 point point NN cord-254436-89zf41xr 52 45 of of IN cord-254436-89zf41xr 52 46 death death NN cord-254436-89zf41xr 52 47 and and CC cord-254436-89zf41xr 52 48 critically critically RB cord-254436-89zf41xr 52 49 severe severe JJ cord-254436-89zf41xr 52 50 outcomes outcome NNS cord-254436-89zf41xr 52 51 ( ( -LRB- cord-254436-89zf41xr 52 52 odds odd NNS cord-254436-89zf41xr 52 53 ratio ratio NN cord-254436-89zf41xr 52 54 0.67 0.67 CD cord-254436-89zf41xr 52 55 , , , cord-254436-89zf41xr 52 56 CI CI NNP cord-254436-89zf41xr 52 57 0.50 0.50 CD cord-254436-89zf41xr 52 58 to to IN cord-254436-89zf41xr 52 59 0.91 0.91 CD cord-254436-89zf41xr 52 60 , , , cord-254436-89zf41xr 52 61 p p NN cord-254436-89zf41xr 52 62 = = SYM cord-254436-89zf41xr 52 63 0.01 0.01 CD cord-254436-89zf41xr 52 64 ) ) -RRB- cord-254436-89zf41xr 52 65 [ [ -LRB- cord-254436-89zf41xr 52 66 16 16 CD cord-254436-89zf41xr 52 67 ] ] -RRB- cord-254436-89zf41xr 52 68 . . . cord-254436-89zf41xr 53 1 This this DT cord-254436-89zf41xr 53 2 was be VBD cord-254436-89zf41xr 53 3 however however RB cord-254436-89zf41xr 53 4 an an DT cord-254436-89zf41xr 53 5 observational observational JJ cord-254436-89zf41xr 53 6 study study NN cord-254436-89zf41xr 53 7 and and CC cord-254436-89zf41xr 53 8 there there EX cord-254436-89zf41xr 53 9 is be VBZ cord-254436-89zf41xr 53 10 as as RB cord-254436-89zf41xr 53 11 yet yet RB cord-254436-89zf41xr 53 12 no no DT cord-254436-89zf41xr 53 13 evidence evidence NN cord-254436-89zf41xr 53 14 as as IN cord-254436-89zf41xr 53 15 to to IN cord-254436-89zf41xr 53 16 whether whether IN cord-254436-89zf41xr 53 17 adding add VBG cord-254436-89zf41xr 53 18 an an DT cord-254436-89zf41xr 53 19 ACEi acei NN cord-254436-89zf41xr 53 20 or or CC cord-254436-89zf41xr 53 21 ARB ARB NNP cord-254436-89zf41xr 53 22 to to IN cord-254436-89zf41xr 53 23 treatment treatment NN cord-254436-89zf41xr 53 24 would would MD cord-254436-89zf41xr 53 25 influence influence VB cord-254436-89zf41xr 53 26 the the DT cord-254436-89zf41xr 53 27 outcome outcome NN cord-254436-89zf41xr 53 28 of of IN cord-254436-89zf41xr 53 29 COVD-19 COVD-19 NNP cord-254436-89zf41xr 53 30 . . . cord-254436-89zf41xr 54 1 Myocardial myocardial JJ cord-254436-89zf41xr 54 2 injury injury NN cord-254436-89zf41xr 54 3 is be VBZ cord-254436-89zf41xr 54 4 found find VBN cord-254436-89zf41xr 54 5 in in IN cord-254436-89zf41xr 54 6 > > $ cord-254436-89zf41xr 54 7 25 25 CD cord-254436-89zf41xr 54 8 % % NN cord-254436-89zf41xr 54 9 of of IN cord-254436-89zf41xr 54 10 critical critical JJ cord-254436-89zf41xr 54 11 cases case NNS cord-254436-89zf41xr 54 12 of of IN cord-254436-89zf41xr 54 13 COVID-19 COVID-19 NNP cord-254436-89zf41xr 54 14 and and CC cord-254436-89zf41xr 54 15 presents present VBZ cord-254436-89zf41xr 54 16 in in IN cord-254436-89zf41xr 54 17 2 2 CD cord-254436-89zf41xr 54 18 patterns pattern NNS cord-254436-89zf41xr 54 19 : : : cord-254436-89zf41xr 54 20 acute acute JJ cord-254436-89zf41xr 54 21 myocardial myocardial JJ cord-254436-89zf41xr 54 22 injury injury NN cord-254436-89zf41xr 54 23 and and CC cord-254436-89zf41xr 54 24 dysfunction dysfunction NN cord-254436-89zf41xr 54 25 on on IN cord-254436-89zf41xr 54 26 presentation presentation NN cord-254436-89zf41xr 54 27 and and CC cord-254436-89zf41xr 54 28 delayed delay VBN cord-254436-89zf41xr 54 29 myocardial myocardial JJ cord-254436-89zf41xr 54 30 injury injury NN cord-254436-89zf41xr 54 31 that that WDT cord-254436-89zf41xr 54 32 develops develop VBZ cord-254436-89zf41xr 54 33 as as IN cord-254436-89zf41xr 54 34 illness illness NN cord-254436-89zf41xr 54 35 severity severity NN cord-254436-89zf41xr 54 36 intensifies intensify VBZ cord-254436-89zf41xr 54 37 [ [ -LRB- cord-254436-89zf41xr 54 38 5 5 CD cord-254436-89zf41xr 54 39 ] ] -RRB- cord-254436-89zf41xr 54 40 . . . cord-254436-89zf41xr 55 1 There there EX cord-254436-89zf41xr 55 2 are be VBP cord-254436-89zf41xr 55 3 also also RB cord-254436-89zf41xr 55 4 potentially potentially RB cord-254436-89zf41xr 55 5 serious serious JJ cord-254436-89zf41xr 55 6 drug drug NN cord-254436-89zf41xr 55 7 - - HYPH cord-254436-89zf41xr 55 8 cardiac cardiac NN cord-254436-89zf41xr 55 9 disease disease NN cord-254436-89zf41xr 55 10 interactions interaction NNS cord-254436-89zf41xr 55 11 affecting affect VBG cord-254436-89zf41xr 55 12 patients patient NNS cord-254436-89zf41xr 55 13 with with IN cord-254436-89zf41xr 55 14 COVID-19 COVID-19 NNP cord-254436-89zf41xr 55 15 and and CC cord-254436-89zf41xr 55 16 associated associate VBD cord-254436-89zf41xr 55 17 cardiovascular cardiovascular JJ cord-254436-89zf41xr 55 18 disease disease NN cord-254436-89zf41xr 55 19 , , , cord-254436-89zf41xr 55 20 for for IN cord-254436-89zf41xr 55 21 example example NN cord-254436-89zf41xr 55 22 from from IN cord-254436-89zf41xr 55 23 empirical empirical JJ cord-254436-89zf41xr 55 24 anti anti JJ cord-254436-89zf41xr 55 25 - - JJ cord-254436-89zf41xr 55 26 inflammatory inflammatory JJ cord-254436-89zf41xr 55 27 treatments treatment NNS cord-254436-89zf41xr 55 28 . . . cord-254436-89zf41xr 56 1 [ [ -LRB- cord-254436-89zf41xr 56 2 6 6 CD cord-254436-89zf41xr 56 3 ] ] -RRB- cord-254436-89zf41xr 56 4 . . . cord-254436-89zf41xr 57 1 SARS SARS NNP cord-254436-89zf41xr 57 2 - - HYPH cord-254436-89zf41xr 57 3 CoV2 CoV2 NNP cord-254436-89zf41xr 57 4 may may MD cord-254436-89zf41xr 57 5 also also RB cord-254436-89zf41xr 57 6 cause cause VB cord-254436-89zf41xr 57 7 hypercoagulability hypercoagulability NN cord-254436-89zf41xr 57 8 , , , cord-254436-89zf41xr 57 9 resulting result VBG cord-254436-89zf41xr 57 10 in in IN cord-254436-89zf41xr 57 11 unexpectedly unexpectedly RB cord-254436-89zf41xr 57 12 severe severe JJ cord-254436-89zf41xr 57 13 lung lung NN cord-254436-89zf41xr 57 14 damage damage NN cord-254436-89zf41xr 57 15 from from IN cord-254436-89zf41xr 57 16 widespread widespread JJ cord-254436-89zf41xr 57 17 thromboses thrombose NNS cord-254436-89zf41xr 57 18 and and CC cord-254436-89zf41xr 57 19 disseminated disseminate VBN cord-254436-89zf41xr 57 20 intravascular intravascular JJ cord-254436-89zf41xr 57 21 coagulation coagulation NN cord-254436-89zf41xr 57 22 adding add VBG cord-254436-89zf41xr 57 23 to to IN cord-254436-89zf41xr 57 24 lung lung NN cord-254436-89zf41xr 57 25 injury injury NN cord-254436-89zf41xr 57 26 from from IN cord-254436-89zf41xr 57 27 COVID-19 COVID-19 NNP cord-254436-89zf41xr 57 28 pneumonia pneumonia NN cord-254436-89zf41xr 57 29 [ [ -LRB- cord-254436-89zf41xr 57 30 17 17 CD cord-254436-89zf41xr 57 31 ] ] -RRB- cord-254436-89zf41xr 57 32 . . . cord-254436-89zf41xr 58 1 These these DT cord-254436-89zf41xr 58 2 features feature NNS cord-254436-89zf41xr 58 3 suggest suggest VBP cord-254436-89zf41xr 58 4 complement complement NN cord-254436-89zf41xr 58 5 - - HYPH cord-254436-89zf41xr 58 6 mediated mediate VBN cord-254436-89zf41xr 58 7 thrombotic thrombotic JJ cord-254436-89zf41xr 58 8 microangiopathy microangiopathy NN cord-254436-89zf41xr 58 9 as as IN cord-254436-89zf41xr 58 10 a a DT cord-254436-89zf41xr 58 11 contributory contributory JJ cord-254436-89zf41xr 58 12 factor factor NN cord-254436-89zf41xr 58 13 and and CC cord-254436-89zf41xr 58 14 may may MD cord-254436-89zf41xr 58 15 give give VB cord-254436-89zf41xr 58 16 clues clue NNS cord-254436-89zf41xr 58 17 to to IN cord-254436-89zf41xr 58 18 treatment treatment NN cord-254436-89zf41xr 58 19 beyond beyond IN cord-254436-89zf41xr 58 20 anticoagulation anticoagulation NN cord-254436-89zf41xr 58 21 to to TO cord-254436-89zf41xr 58 22 prevent prevent VB cord-254436-89zf41xr 58 23 life life NN cord-254436-89zf41xr 58 24 - - HYPH cord-254436-89zf41xr 58 25 threatening threaten VBG cord-254436-89zf41xr 58 26 microangiopathy microangiopathy NN cord-254436-89zf41xr 58 27 [ [ -LRB- cord-254436-89zf41xr 58 28 17 17 CD cord-254436-89zf41xr 58 29 , , , cord-254436-89zf41xr 58 30 18 18 CD cord-254436-89zf41xr 58 31 ] ] -RRB- cord-254436-89zf41xr 58 32 . . . cord-254436-89zf41xr 59 1 An an DT cord-254436-89zf41xr 59 2 indirect indirect JJ cord-254436-89zf41xr 59 3 factor factor NN cord-254436-89zf41xr 59 4 in in IN cord-254436-89zf41xr 59 5 COVID-19-related covid-19-related JJ cord-254436-89zf41xr 59 6 increased increase VBD cord-254436-89zf41xr 59 7 severity severity NN cord-254436-89zf41xr 59 8 of of IN cord-254436-89zf41xr 59 9 cardiovascular cardiovascular JJ cord-254436-89zf41xr 59 10 disease disease NN cord-254436-89zf41xr 59 11 is be VBZ cord-254436-89zf41xr 59 12 malnutrition malnutrition NN cord-254436-89zf41xr 59 13 in in IN cord-254436-89zf41xr 59 14 patients patient NNS cord-254436-89zf41xr 59 15 self self NN cord-254436-89zf41xr 59 16 - - HYPH cord-254436-89zf41xr 59 17 isolating isolate VBG cord-254436-89zf41xr 59 18 at at IN cord-254436-89zf41xr 59 19 home home NN cord-254436-89zf41xr 59 20 . . . cord-254436-89zf41xr 60 1 This this DT cord-254436-89zf41xr 60 2 may may MD cord-254436-89zf41xr 60 3 directly directly RB cord-254436-89zf41xr 60 4 increase increase VB cord-254436-89zf41xr 60 5 risk risk NN cord-254436-89zf41xr 60 6 of of IN cord-254436-89zf41xr 60 7 falls fall NNS cord-254436-89zf41xr 60 8 , , , cord-254436-89zf41xr 60 9 heart heart NN cord-254436-89zf41xr 60 10 attack attack NN cord-254436-89zf41xr 60 11 and and CC cord-254436-89zf41xr 60 12 stroke stroke NN cord-254436-89zf41xr 60 13 , , , cord-254436-89zf41xr 60 14 especially especially RB cord-254436-89zf41xr 60 15 when when WRB cord-254436-89zf41xr 60 16 patients patient NNS cord-254436-89zf41xr 60 17 continue continue VBP cord-254436-89zf41xr 60 18 diuretics diuretic NNS cord-254436-89zf41xr 60 19 and and CC cord-254436-89zf41xr 60 20 other other JJ cord-254436-89zf41xr 60 21 blood blood NN cord-254436-89zf41xr 60 22 pressure pressure NN cord-254436-89zf41xr 60 23 - - HYPH cord-254436-89zf41xr 60 24 lowering lower VBG cord-254436-89zf41xr 60 25 medicines medicine NNS cord-254436-89zf41xr 60 26 despite despite IN cord-254436-89zf41xr 60 27 reduced reduce VBN cord-254436-89zf41xr 60 28 oral oral JJ cord-254436-89zf41xr 60 29 intake intake NN cord-254436-89zf41xr 60 30 of of IN cord-254436-89zf41xr 60 31 food food NN cord-254436-89zf41xr 60 32 and and CC cord-254436-89zf41xr 60 33 drinka drinka NN cord-254436-89zf41xr 60 34 recognized recognize VBN cord-254436-89zf41xr 60 35 cause cause NN cord-254436-89zf41xr 60 36 of of IN cord-254436-89zf41xr 60 37 hypotension hypotension NN cord-254436-89zf41xr 60 38 and and CC cord-254436-89zf41xr 60 39 falls fall VBZ cord-254436-89zf41xr 60 40 . . . cord-254436-89zf41xr 61 1 Other other JJ cord-254436-89zf41xr 61 2 indirect indirect JJ cord-254436-89zf41xr 61 3 reasons reason NNS cord-254436-89zf41xr 61 4 for for IN cord-254436-89zf41xr 61 5 concern concern NN cord-254436-89zf41xr 61 6 about about IN cord-254436-89zf41xr 61 7 increased increase VBN cord-254436-89zf41xr 61 8 prevalence prevalence NN cord-254436-89zf41xr 61 9 and and CC cord-254436-89zf41xr 61 10 severity severity NN cord-254436-89zf41xr 61 11 of of IN cord-254436-89zf41xr 61 12 cardiovascular cardiovascular JJ cord-254436-89zf41xr 61 13 disease disease NN cord-254436-89zf41xr 61 14 because because IN cord-254436-89zf41xr 61 15 of of IN cord-254436-89zf41xr 61 16 the the DT cord-254436-89zf41xr 61 17 COVID-19 covid-19 JJ cord-254436-89zf41xr 61 18 pandemic pandemic NN cord-254436-89zf41xr 61 19 include include VBP cord-254436-89zf41xr 61 20 poorer poor JJR cord-254436-89zf41xr 61 21 recognition recognition NN cord-254436-89zf41xr 61 22 and and CC cord-254436-89zf41xr 61 23 control control NN cord-254436-89zf41xr 61 24 of of IN cord-254436-89zf41xr 61 25 cardiovascular cardiovascular JJ cord-254436-89zf41xr 61 26 risk risk NN cord-254436-89zf41xr 61 27 factors factor NNS cord-254436-89zf41xr 61 28 and and CC cord-254436-89zf41xr 61 29 established establish VBD cord-254436-89zf41xr 61 30 serious serious JJ cord-254436-89zf41xr 61 31 disorders disorder NNS cord-254436-89zf41xr 61 32 of of IN cord-254436-89zf41xr 61 33 the the DT cord-254436-89zf41xr 61 34 heart heart NN cord-254436-89zf41xr 61 35 , , , cord-254436-89zf41xr 61 36 brain brain NN cord-254436-89zf41xr 61 37 and and CC cord-254436-89zf41xr 61 38 circulation circulation NN cord-254436-89zf41xr 61 39 due due IN cord-254436-89zf41xr 61 40 to to IN cord-254436-89zf41xr 61 41 reduced reduce VBN cord-254436-89zf41xr 61 42 access access NN cord-254436-89zf41xr 61 43 to to IN cord-254436-89zf41xr 61 44 medical medical JJ cord-254436-89zf41xr 61 45 services service NNS cord-254436-89zf41xr 61 46 . . . cord-254436-89zf41xr 62 1 Particularly particularly RB cord-254436-89zf41xr 62 2 in in IN cord-254436-89zf41xr 62 3 less less RBR cord-254436-89zf41xr 62 4 developed developed JJ cord-254436-89zf41xr 62 5 countries country NNS cord-254436-89zf41xr 62 6 , , , cord-254436-89zf41xr 62 7 public public JJ cord-254436-89zf41xr 62 8 transport transport NN cord-254436-89zf41xr 62 9 is be VBZ cord-254436-89zf41xr 62 10 vital vital JJ cord-254436-89zf41xr 62 11 for for IN cord-254436-89zf41xr 62 12 access access NN cord-254436-89zf41xr 62 13 to to IN cord-254436-89zf41xr 62 14 health health NN cord-254436-89zf41xr 62 15 care care NN cord-254436-89zf41xr 62 16 facilities facility NNS cord-254436-89zf41xr 62 17 . . . cord-254436-89zf41xr 63 1 Both both DT cord-254436-89zf41xr 63 2 public public JJ cord-254436-89zf41xr 63 3 transport transport NN cord-254436-89zf41xr 63 4 services service NNS cord-254436-89zf41xr 63 5 and and CC cord-254436-89zf41xr 63 6 medical medical JJ cord-254436-89zf41xr 63 7 facilities facility NNS cord-254436-89zf41xr 63 8 have have VBP cord-254436-89zf41xr 63 9 been be VBN cord-254436-89zf41xr 63 10 seriously seriously RB cord-254436-89zf41xr 63 11 limited limit VBN cord-254436-89zf41xr 63 12 during during IN cord-254436-89zf41xr 63 13 COVID-19 covid-19 JJ cord-254436-89zf41xr 63 14 restrictions restriction NNS cord-254436-89zf41xr 63 15 and and CC cord-254436-89zf41xr 63 16 availability availability NN cord-254436-89zf41xr 63 17 of of IN cord-254436-89zf41xr 63 18 funds fund NNS cord-254436-89zf41xr 63 19 to to TO cord-254436-89zf41xr 63 20 pay pay VB cord-254436-89zf41xr 63 21 for for IN cord-254436-89zf41xr 63 22 medical medical JJ cord-254436-89zf41xr 63 23 services service NNS cord-254436-89zf41xr 63 24 has have VBZ cord-254436-89zf41xr 63 25 been be VBN cord-254436-89zf41xr 63 26 severely severely RB cord-254436-89zf41xr 63 27 reduced reduce VBN cord-254436-89zf41xr 63 28 . . . cord-254436-89zf41xr 64 1 For for IN cord-254436-89zf41xr 64 2 example example NN cord-254436-89zf41xr 64 3 , , , cord-254436-89zf41xr 64 4 in in IN cord-254436-89zf41xr 64 5 India India NNP cord-254436-89zf41xr 64 6 , , , cord-254436-89zf41xr 64 7 over over IN cord-254436-89zf41xr 64 8 75 75 CD cord-254436-89zf41xr 64 9 % % NN cord-254436-89zf41xr 64 10 of of IN cord-254436-89zf41xr 64 11 the the DT cord-254436-89zf41xr 64 12 country country NN cord-254436-89zf41xr 64 13 's 's POS cord-254436-89zf41xr 64 14 substantial substantial JJ cord-254436-89zf41xr 64 15 workforce workforce NN cord-254436-89zf41xr 64 16 of of IN cord-254436-89zf41xr 64 17 100 100 CD cord-254436-89zf41xr 64 18 million million CD cord-254436-89zf41xr 64 19 migrant migrant JJ cord-254436-89zf41xr 64 20 workers worker NNS cord-254436-89zf41xr 64 21 lost lose VBD cord-254436-89zf41xr 64 22 their -PRON- PRP$ cord-254436-89zf41xr 64 23 jobs job NNS cord-254436-89zf41xr 64 24 overnight overnight RB cord-254436-89zf41xr 64 25 , , , cord-254436-89zf41xr 64 26 public public JJ cord-254436-89zf41xr 64 27 transport transport NN cord-254436-89zf41xr 64 28 services service NNS cord-254436-89zf41xr 64 29 were be VBD cord-254436-89zf41xr 64 30 critically critically RB cord-254436-89zf41xr 64 31 reduced reduce VBN cord-254436-89zf41xr 64 32 , , , cord-254436-89zf41xr 64 33 and and CC cord-254436-89zf41xr 64 34 many many JJ cord-254436-89zf41xr 64 35 healthcare healthcare NN cord-254436-89zf41xr 64 36 facilities facility NNS cord-254436-89zf41xr 64 37 closed close VBD cord-254436-89zf41xr 64 38 [ [ -LRB- cord-254436-89zf41xr 64 39 19 19 CD cord-254436-89zf41xr 64 40 ] ] -RRB- cord-254436-89zf41xr 64 41 . . . cord-254436-89zf41xr 65 1 Increasing increase VBG cord-254436-89zf41xr 65 2 recognition recognition NN cord-254436-89zf41xr 65 3 of of IN cord-254436-89zf41xr 65 4 these these DT cord-254436-89zf41xr 65 5 links link NNS cord-254436-89zf41xr 65 6 between between IN cord-254436-89zf41xr 65 7 cardiovascular cardiovascular JJ cord-254436-89zf41xr 65 8 risk risk NN cord-254436-89zf41xr 65 9 and and CC cord-254436-89zf41xr 65 10 disease disease NN cord-254436-89zf41xr 65 11 and and CC cord-254436-89zf41xr 65 12 severity severity NN cord-254436-89zf41xr 65 13 of of IN cord-254436-89zf41xr 65 14 COVID-19 COVID-19 NNP cord-254436-89zf41xr 65 15 , , , cord-254436-89zf41xr 65 16 including include VBG cord-254436-89zf41xr 65 17 mortality mortality NN cord-254436-89zf41xr 65 18 , , , cord-254436-89zf41xr 65 19 offer offer VB cord-254436-89zf41xr 65 20 opportunities opportunity NNS cord-254436-89zf41xr 65 21 to to TO cord-254436-89zf41xr 65 22 improve improve VB cord-254436-89zf41xr 65 23 outcomes outcome NNS cord-254436-89zf41xr 65 24 of of IN cord-254436-89zf41xr 65 25 COVID-19 covid-19 CD cord-254436-89zf41xr 65 26 in in IN cord-254436-89zf41xr 65 27 the the DT cord-254436-89zf41xr 65 28 large large JJ cord-254436-89zf41xr 65 29 number number NN cord-254436-89zf41xr 65 30 of of IN cord-254436-89zf41xr 65 31 patients patient NNS cord-254436-89zf41xr 65 32 with with IN cord-254436-89zf41xr 65 33 these these DT cord-254436-89zf41xr 65 34 common common JJ cord-254436-89zf41xr 65 35 disorders disorder NNS cord-254436-89zf41xr 65 36 . . . cord-254436-89zf41xr 66 1 Understanding understand VBG cord-254436-89zf41xr 66 2 the the DT cord-254436-89zf41xr 66 3 pathophysiology pathophysiology NN cord-254436-89zf41xr 66 4 and and CC cord-254436-89zf41xr 66 5 exploring explore VBG cord-254436-89zf41xr 66 6 potential potential JJ cord-254436-89zf41xr 66 7 solutions solution NNS cord-254436-89zf41xr 66 8 and and CC cord-254436-89zf41xr 66 9 treatments treatment NNS cord-254436-89zf41xr 66 10 to to TO cord-254436-89zf41xr 66 11 reverse reverse VB cord-254436-89zf41xr 66 12 worse bad JJR cord-254436-89zf41xr 66 13 outcomes outcome NNS cord-254436-89zf41xr 66 14 in in IN cord-254436-89zf41xr 66 15 patients patient NNS cord-254436-89zf41xr 66 16 at at IN cord-254436-89zf41xr 66 17 increased increase VBN cord-254436-89zf41xr 66 18 cardiovascular cardiovascular JJ cord-254436-89zf41xr 66 19 risk risk NN cord-254436-89zf41xr 66 20 is be VBZ cord-254436-89zf41xr 66 21 a a DT cord-254436-89zf41xr 66 22 priority priority NN cord-254436-89zf41xr 66 23 for for IN cord-254436-89zf41xr 66 24 health health NN cord-254436-89zf41xr 66 25 researchers researcher NNS cord-254436-89zf41xr 66 26 and and CC cord-254436-89zf41xr 66 27 clinical clinical JJ cord-254436-89zf41xr 66 28 health health NN cord-254436-89zf41xr 66 29 services service NNS cord-254436-89zf41xr 66 30 around around IN cord-254436-89zf41xr 66 31 the the DT cord-254436-89zf41xr 66 32 world world NN cord-254436-89zf41xr 66 33 . . . cord-254436-89zf41xr 67 1 This this DT cord-254436-89zf41xr 67 2 is be VBZ cord-254436-89zf41xr 67 3 all all PDT cord-254436-89zf41xr 67 4 the the DT cord-254436-89zf41xr 67 5 more more RBR cord-254436-89zf41xr 67 6 pressing pressing JJ cord-254436-89zf41xr 67 7 as as IN cord-254436-89zf41xr 67 8 there there EX cord-254436-89zf41xr 67 9 is be VBZ cord-254436-89zf41xr 67 10 an an DT cord-254436-89zf41xr 67 11 international international JJ cord-254436-89zf41xr 67 12 epidemic epidemic NN cord-254436-89zf41xr 67 13 of of IN cord-254436-89zf41xr 67 14 the the DT cord-254436-89zf41xr 67 15 preventable preventable JJ cord-254436-89zf41xr 67 16 cardiovascular cardiovascular JJ cord-254436-89zf41xr 67 17 risk risk NN cord-254436-89zf41xr 67 18 factors factor NNS cord-254436-89zf41xr 67 19 which which WDT cord-254436-89zf41xr 67 20 have have VBP cord-254436-89zf41xr 67 21 been be VBN cord-254436-89zf41xr 67 22 linked link VBN cord-254436-89zf41xr 67 23 to to IN cord-254436-89zf41xr 67 24 increased increase VBN cord-254436-89zf41xr 67 25 severity severity NN cord-254436-89zf41xr 67 26 of of IN cord-254436-89zf41xr 67 27 COVID-19 COVID-19 NNP cord-254436-89zf41xr 67 28 . . . cord-254436-89zf41xr 67 29 Health health NN cord-254436-89zf41xr 67 30 policy policy NN cord-254436-89zf41xr 67 31 makers maker NNS cord-254436-89zf41xr 67 32 also also RB cord-254436-89zf41xr 67 33 need need VBP cord-254436-89zf41xr 67 34 to to TO cord-254436-89zf41xr 67 35 take take VB cord-254436-89zf41xr 67 36 steps step NNS cord-254436-89zf41xr 67 37 to to TO cord-254436-89zf41xr 67 38 extend extend VB cord-254436-89zf41xr 67 39 influenza influenza NN cord-254436-89zf41xr 67 40 immunization immunization NN cord-254436-89zf41xr 67 41 to to IN cord-254436-89zf41xr 67 42 all all DT cord-254436-89zf41xr 67 43 groups group NNS cord-254436-89zf41xr 67 44 now now RB cord-254436-89zf41xr 67 45 recognized recognize VBN cord-254436-89zf41xr 67 46 to to TO cord-254436-89zf41xr 67 47 be be VB cord-254436-89zf41xr 67 48 at at IN cord-254436-89zf41xr 67 49 risk risk NN cord-254436-89zf41xr 67 50 of of IN cord-254436-89zf41xr 67 51 more more RBR cord-254436-89zf41xr 67 52 serious serious JJ cord-254436-89zf41xr 67 53 COVID-19 COVID-19 NNP cord-254436-89zf41xr 67 54 , , , cord-254436-89zf41xr 67 55 including include VBG cord-254436-89zf41xr 67 56 the the DT cord-254436-89zf41xr 67 57 obese obese JJ cord-254436-89zf41xr 67 58 , , , cord-254436-89zf41xr 67 59 others other NNS cord-254436-89zf41xr 67 60 with with IN cord-254436-89zf41xr 67 61 increased increase VBN cord-254436-89zf41xr 67 62 cardiovascular cardiovascular JJ cord-254436-89zf41xr 67 63 risk risk NN cord-254436-89zf41xr 67 64 and and CC cord-254436-89zf41xr 67 65 people people NNS cord-254436-89zf41xr 67 66 from from IN cord-254436-89zf41xr 67 67 black black JJ cord-254436-89zf41xr 67 68 and and CC cord-254436-89zf41xr 67 69 other other JJ cord-254436-89zf41xr 67 70 at at IN cord-254436-89zf41xr 67 71 risk risk NN cord-254436-89zf41xr 67 72 ethnic ethnic JJ cord-254436-89zf41xr 67 73 minorities minority NNS cord-254436-89zf41xr 67 74 . . . cord-254436-89zf41xr 68 1 Policy policy NN cord-254436-89zf41xr 68 2 makers maker NNS cord-254436-89zf41xr 68 3 will will MD cord-254436-89zf41xr 68 4 need need VB cord-254436-89zf41xr 68 5 to to TO cord-254436-89zf41xr 68 6 make make VB cord-254436-89zf41xr 68 7 extra extra JJ cord-254436-89zf41xr 68 8 efforts effort NNS cord-254436-89zf41xr 68 9 to to TO cord-254436-89zf41xr 68 10 make make VB cord-254436-89zf41xr 68 11 sure sure JJ cord-254436-89zf41xr 68 12 that that IN cord-254436-89zf41xr 68 13 these these DT cord-254436-89zf41xr 68 14 vulnerable vulnerable JJ cord-254436-89zf41xr 68 15 people people NNS cord-254436-89zf41xr 68 16 take take VBP cord-254436-89zf41xr 68 17 part part NN cord-254436-89zf41xr 68 18 in in IN cord-254436-89zf41xr 68 19 influenza influenza NN cord-254436-89zf41xr 68 20 immunization immunization NN cord-254436-89zf41xr 68 21 programmes programme NNS cord-254436-89zf41xr 68 22 . . . cord-254436-89zf41xr 69 1 This this DT cord-254436-89zf41xr 69 2 requires require VBZ cord-254436-89zf41xr 69 3 measures measure NNS cord-254436-89zf41xr 69 4 to to TO cord-254436-89zf41xr 69 5 make make VB cord-254436-89zf41xr 69 6 sure sure JJ cord-254436-89zf41xr 69 7 that that IN cord-254436-89zf41xr 69 8 accessing access VBG cord-254436-89zf41xr 69 9 points point NNS cord-254436-89zf41xr 69 10 of of IN cord-254436-89zf41xr 69 11 care care NN cord-254436-89zf41xr 69 12 will will MD cord-254436-89zf41xr 69 13 not not RB cord-254436-89zf41xr 69 14 put put VB cord-254436-89zf41xr 69 15 people people NNS cord-254436-89zf41xr 69 16 at at IN cord-254436-89zf41xr 69 17 risk risk NN cord-254436-89zf41xr 69 18 of of IN cord-254436-89zf41xr 69 19 acquiring acquire VBG cord-254436-89zf41xr 69 20 COVID-19 covid-19 CD cord-254436-89zf41xr 69 21 . . . cord-254436-89zf41xr 70 1 Policy policy NN cord-254436-89zf41xr 70 2 makers maker NNS cord-254436-89zf41xr 70 3 also also RB cord-254436-89zf41xr 70 4 need need VBP cord-254436-89zf41xr 70 5 to to TO cord-254436-89zf41xr 70 6 build build VB cord-254436-89zf41xr 70 7 public public JJ cord-254436-89zf41xr 70 8 awareness awareness NN cord-254436-89zf41xr 70 9 of of IN cord-254436-89zf41xr 70 10 the the DT cord-254436-89zf41xr 70 11 current current JJ cord-254436-89zf41xr 70 12 extra extra JJ cord-254436-89zf41xr 70 13 importance importance NN cord-254436-89zf41xr 70 14 of of IN cord-254436-89zf41xr 70 15 influenza influenza NN cord-254436-89zf41xr 70 16 immunization immunization NN cord-254436-89zf41xr 70 17 and and CC cord-254436-89zf41xr 70 18 confidence confidence NN cord-254436-89zf41xr 70 19 in in IN cord-254436-89zf41xr 70 20 the the DT cord-254436-89zf41xr 70 21 safety safety NN cord-254436-89zf41xr 70 22 of of IN cord-254436-89zf41xr 70 23 accessing access VBG cord-254436-89zf41xr 70 24 medical medical JJ cord-254436-89zf41xr 70 25 services service NNS cord-254436-89zf41xr 70 26 . . . cord-254436-89zf41xr 71 1 The the DT cord-254436-89zf41xr 71 2 involvement involvement NN cord-254436-89zf41xr 71 3 of of IN cord-254436-89zf41xr 71 4 policy policy NN cord-254436-89zf41xr 71 5 makers maker NNS cord-254436-89zf41xr 71 6 to to TO cord-254436-89zf41xr 71 7 ensure ensure VB cord-254436-89zf41xr 71 8 sustained sustain VBN cord-254436-89zf41xr 71 9 financial financial JJ cord-254436-89zf41xr 71 10 and and CC cord-254436-89zf41xr 71 11 social social JJ cord-254436-89zf41xr 71 12 solutions solution NNS cord-254436-89zf41xr 71 13 for for IN cord-254436-89zf41xr 71 14 COVID-19 COVID-19 NNP cord-254436-89zf41xr 71 15 is be VBZ cord-254436-89zf41xr 71 16 urgently urgently RB cord-254436-89zf41xr 71 17 needed need VBN cord-254436-89zf41xr 71 18 , , , cord-254436-89zf41xr 71 19 to to TO cord-254436-89zf41xr 71 20 complement complement VB cord-254436-89zf41xr 71 21 the the DT cord-254436-89zf41xr 71 22 efforts effort NNS cord-254436-89zf41xr 71 23 against against IN cord-254436-89zf41xr 71 24 COVID-19 covid-19 CD cord-254436-89zf41xr 71 25 of of IN cord-254436-89zf41xr 71 26 health health NN cord-254436-89zf41xr 71 27 professionals professional NNS cord-254436-89zf41xr 71 28 , , , cord-254436-89zf41xr 71 29 regulators regulator NNS cord-254436-89zf41xr 71 30 and and CC cord-254436-89zf41xr 71 31 the the DT cord-254436-89zf41xr 71 32 pharmaceutical pharmaceutical NN cord-254436-89zf41xr 71 33 and and CC cord-254436-89zf41xr 71 34 biotechnology biotechnology NN cord-254436-89zf41xr 71 35 industries industry NNS cord-254436-89zf41xr 71 36 . . . cord-254436-89zf41xr 72 1 These these DT cord-254436-89zf41xr 72 2 efforts effort NNS cord-254436-89zf41xr 72 3 will will MD cord-254436-89zf41xr 72 4 not not RB cord-254436-89zf41xr 72 5 be be VB cord-254436-89zf41xr 72 6 successful successful JJ cord-254436-89zf41xr 72 7 without without IN cord-254436-89zf41xr 72 8 also also RB cord-254436-89zf41xr 72 9 addressing address VBG cord-254436-89zf41xr 72 10 the the DT cord-254436-89zf41xr 72 11 cardiovascular cardiovascular JJ cord-254436-89zf41xr 72 12 and and CC cord-254436-89zf41xr 72 13 other other JJ cord-254436-89zf41xr 72 14 factors factor NNS cord-254436-89zf41xr 72 15 that that WDT cord-254436-89zf41xr 72 16 contribute contribute VBP cord-254436-89zf41xr 72 17 to to IN cord-254436-89zf41xr 72 18 higher high JJR cord-254436-89zf41xr 72 19 risk risk NN cord-254436-89zf41xr 72 20 from from IN cord-254436-89zf41xr 72 21 COVID-19 COVID-19 NNP cord-254436-89zf41xr 72 22 . . . cord-254436-89zf41xr 73 1 Links link NNS cord-254436-89zf41xr 73 2 to to IN cord-254436-89zf41xr 73 3 the the DT cord-254436-89zf41xr 73 4 severity severity NN cord-254436-89zf41xr 73 5 of of IN cord-254436-89zf41xr 73 6 COVID-19 COVID-19 NNP cord-254436-89zf41xr 73 7 make make VB cord-254436-89zf41xr 73 8 it -PRON- PRP cord-254436-89zf41xr 73 9 all all PDT cord-254436-89zf41xr 73 10 the the DT cord-254436-89zf41xr 73 11 more more RBR cord-254436-89zf41xr 73 12 pressing press VBG cord-254436-89zf41xr 73 13 for for IN cord-254436-89zf41xr 73 14 policy policy NN cord-254436-89zf41xr 73 15 makers maker NNS cord-254436-89zf41xr 73 16 and and CC cord-254436-89zf41xr 73 17 public public JJ cord-254436-89zf41xr 73 18 health health NN cord-254436-89zf41xr 73 19 agencies agency NNS cord-254436-89zf41xr 73 20 to to TO cord-254436-89zf41xr 73 21 address address VB cord-254436-89zf41xr 73 22 underlying underlying JJ cord-254436-89zf41xr 73 23 causes cause NNS cord-254436-89zf41xr 73 24 and and CC cord-254436-89zf41xr 73 25 to to TO cord-254436-89zf41xr 73 26 reduce reduce VB cord-254436-89zf41xr 73 27 the the DT cord-254436-89zf41xr 73 28 incidence incidence NN cord-254436-89zf41xr 73 29 and and CC cord-254436-89zf41xr 73 30 severity severity NN cord-254436-89zf41xr 73 31 of of IN cord-254436-89zf41xr 73 32 preventable preventable JJ cord-254436-89zf41xr 73 33 cardiovascular cardiovascular JJ cord-254436-89zf41xr 73 34 risk risk NN cord-254436-89zf41xr 73 35 . . . cord-254436-89zf41xr 74 1 Situation situation NN cord-254436-89zf41xr 74 2 updates update NNS cord-254436-89zf41xr 74 3 . . . cord-254436-89zf41xr 75 1 Website website NN cord-254436-89zf41xr 75 2 for for IN cord-254436-89zf41xr 75 3 the the DT cord-254436-89zf41xr 75 4 European European NNP cord-254436-89zf41xr 75 5 Centre Centre NNP cord-254436-89zf41xr 75 6 for for IN cord-254436-89zf41xr 75 7 Disease Disease NNP cord-254436-89zf41xr 75 8 Prevention Prevention NNP cord-254436-89zf41xr 75 9 and and CC cord-254436-89zf41xr 75 10 Control Control NNP cord-254436-89zf41xr 75 11 . . . cord-254436-89zf41xr 76 1 Accessed access VBN cord-254436-89zf41xr 76 2 27 27 CD cord-254436-89zf41xr 76 3 th th IN cord-254436-89zf41xr 76 4 A a DT cord-254436-89zf41xr 76 5 pneumonia pneumonia NN cord-254436-89zf41xr 76 6 outbreak outbreak NN cord-254436-89zf41xr 76 7 associated associate VBN cord-254436-89zf41xr 76 8 with with IN cord-254436-89zf41xr 76 9 a a DT cord-254436-89zf41xr 76 10 new new JJ cord-254436-89zf41xr 76 11 coronavirus coronavirus NN cord-254436-89zf41xr 76 12 of of IN cord-254436-89zf41xr 76 13 probable probable JJ cord-254436-89zf41xr 76 14 bat bat NN cord-254436-89zf41xr 76 15 origin origin NN cord-254436-89zf41xr 76 16 UK UK NNP cord-254436-89zf41xr 76 17 coronavirus coronavirus NN cord-254436-89zf41xr 76 18 live live VB cord-254436-89zf41xr 76 19 : : : cord-254436-89zf41xr 77 1 daily daily JJ cord-254436-89zf41xr 77 2 cases case NNS cord-254436-89zf41xr 77 3 tally tally VBP cord-254436-89zf41xr 77 4 jumps jump VBZ cord-254436-89zf41xr 77 5 by by IN cord-254436-89zf41xr 77 6 nearly nearly RB cord-254436-89zf41xr 77 7 500 500 CD cord-254436-89zf41xr 77 8 to to TO cord-254436-89zf41xr 77 9 reach reach VB cord-254436-89zf41xr 77 10 1,522 1,522 CD cord-254436-89zf41xr 77 11 . . . cord-254436-89zf41xr 78 1 UK UK NNP cord-254436-89zf41xr 78 2 Guardian Guardian NNP cord-254436-89zf41xr 78 3 News News NNP cord-254436-89zf41xr 78 4 website website NN cord-254436-89zf41xr 78 5 Vaccines vaccine NNS cord-254436-89zf41xr 78 6 and and CC cord-254436-89zf41xr 78 7 treatment treatment NN cord-254436-89zf41xr 78 8 of of IN cord-254436-89zf41xr 78 9 COVID-19 COVID-19 NNP cord-254436-89zf41xr 78 10 . . . cord-254436-89zf41xr 79 1 European European NNP cord-254436-89zf41xr 79 2 Centre Centre NNP cord-254436-89zf41xr 79 3 for for IN cord-254436-89zf41xr 79 4 Disease Disease NNP cord-254436-89zf41xr 79 5 Prevention Prevention NNP cord-254436-89zf41xr 79 6 and and CC cord-254436-89zf41xr 79 7 Control Control NNP cord-254436-89zf41xr 79 8 EMA EMA NNP cord-254436-89zf41xr 79 9 to to TO cord-254436-89zf41xr 79 10 monitor monitor VB cord-254436-89zf41xr 79 11 real real JJ cord-254436-89zf41xr 79 12 world world NN cord-254436-89zf41xr 79 13 use use NN cord-254436-89zf41xr 79 14 of of IN cord-254436-89zf41xr 79 15 COVID-19 covid-19 JJ cord-254436-89zf41xr 79 16 treatments treatment NNS cord-254436-89zf41xr 79 17 and and CC cord-254436-89zf41xr 79 18 vaccines vaccine NNS cord-254436-89zf41xr 79 19 COVID-19 covid-19 VBP cord-254436-89zf41xr 79 20 and and CC cord-254436-89zf41xr 79 21 cardiovascular cardiovascular JJ cord-254436-89zf41xr 79 22 disease disease NN cord-254436-89zf41xr 79 23 : : : cord-254436-89zf41xr 79 24 from from IN cord-254436-89zf41xr 79 25 basic basic JJ cord-254436-89zf41xr 79 26 mechanisms mechanism NNS cord-254436-89zf41xr 79 27 to to IN cord-254436-89zf41xr 79 28 clinical clinical JJ cord-254436-89zf41xr 79 29 perspectives perspective NNS cord-254436-89zf41xr 79 30 Clinical clinical JJ cord-254436-89zf41xr 79 31 determinants determinant NNS cord-254436-89zf41xr 79 32 for for IN cord-254436-89zf41xr 79 33 fatality fatality NN cord-254436-89zf41xr 79 34 of of IN cord-254436-89zf41xr 79 35 44,672 44,672 CD cord-254436-89zf41xr 79 36 patients patient NNS cord-254436-89zf41xr 79 37 with with IN cord-254436-89zf41xr 79 38 COVID-19 COVID-19 NNP cord-254436-89zf41xr 79 39 . . . cord-254436-89zf41xr 80 1 Crit Crit NNP cord-254436-89zf41xr 80 2 Care Care NNP cord-254436-89zf41xr 80 3 Individuals individual NNS cord-254436-89zf41xr 80 4 with with IN cord-254436-89zf41xr 80 5 obesity obesity NN cord-254436-89zf41xr 80 6 and and CC cord-254436-89zf41xr 80 7 COVID-19 covid-19 NN cord-254436-89zf41xr 80 8 : : : cord-254436-89zf41xr 80 9 A a DT cord-254436-89zf41xr 80 10 global global JJ cord-254436-89zf41xr 80 11 perspective perspective NN cord-254436-89zf41xr 80 12 on on IN cord-254436-89zf41xr 80 13 the the DT cord-254436-89zf41xr 80 14 epidemiology epidemiology NN cord-254436-89zf41xr 80 15 and and CC cord-254436-89zf41xr 80 16 biological biological JJ cord-254436-89zf41xr 80 17 relationships relationship NNS cord-254436-89zf41xr 81 1 Asian asian JJ cord-254436-89zf41xr 81 2 and and CC cord-254436-89zf41xr 81 3 Minority Minority NNP cord-254436-89zf41xr 81 4 Ethnic ethnic JJ cord-254436-89zf41xr 81 5 groups group NNS cord-254436-89zf41xr 81 6 in in IN cord-254436-89zf41xr 81 7 England England NNP cord-254436-89zf41xr 81 8 are be VBP cord-254436-89zf41xr 81 9 at at IN cord-254436-89zf41xr 81 10 increased increase VBN cord-254436-89zf41xr 81 11 risk risk NN cord-254436-89zf41xr 81 12 of of IN cord-254436-89zf41xr 81 13 death death NN cord-254436-89zf41xr 81 14 from from IN cord-254436-89zf41xr 81 15 COVID-19 covid-19 JJ cord-254436-89zf41xr 81 16 : : : cord-254436-89zf41xr 81 17 indirect indirect JJ cord-254436-89zf41xr 81 18 standardisation standardisation NN cord-254436-89zf41xr 81 19 of of IN cord-254436-89zf41xr 81 20 NHS NHS NNP cord-254436-89zf41xr 81 21 mortality mortality NN cord-254436-89zf41xr 81 22 data datum NNS cord-254436-89zf41xr 81 23 Obesity obesity NN cord-254436-89zf41xr 81 24 Impairs impair VBZ cord-254436-89zf41xr 81 25 the the DT cord-254436-89zf41xr 81 26 Adaptive Adaptive NNP cord-254436-89zf41xr 81 27 Immune Immune NNP cord-254436-89zf41xr 81 28 Response Response NNP cord-254436-89zf41xr 81 29 to to IN cord-254436-89zf41xr 81 30 Influenza Influenza NNP cord-254436-89zf41xr 81 31 Virus Virus NNP cord-254436-89zf41xr 81 32 Soft soft JJ cord-254436-89zf41xr 81 33 power power NN cord-254436-89zf41xr 81 34 and and CC cord-254436-89zf41xr 81 35 global global JJ cord-254436-89zf41xr 81 36 health health NN cord-254436-89zf41xr 81 37 : : : cord-254436-89zf41xr 81 38 the the DT cord-254436-89zf41xr 81 39 sustainable sustainable JJ cord-254436-89zf41xr 81 40 development development NN cord-254436-89zf41xr 81 41 goals goal NNS cord-254436-89zf41xr 81 42 ( ( -LRB- cord-254436-89zf41xr 81 43 SDGs SDGs NNP cord-254436-89zf41xr 81 44 ) ) -RRB- cord-254436-89zf41xr 81 45 era era NN cord-254436-89zf41xr 81 46 health health NN cord-254436-89zf41xr 81 47 agendas agenda NNS cord-254436-89zf41xr 81 48 of of IN cord-254436-89zf41xr 81 49 the the DT cord-254436-89zf41xr 81 50 G7 G7 NNP cord-254436-89zf41xr 81 51 , , , cord-254436-89zf41xr 81 52 G20 G20 NNP cord-254436-89zf41xr 81 53 and and CC cord-254436-89zf41xr 81 54 BRICS BRICS NNP cord-254436-89zf41xr 81 55 . . . cord-254436-89zf41xr 82 1 BMC BMC NNP cord-254436-89zf41xr 82 2 Public Public NNP cord-254436-89zf41xr 82 3 Health Health NNP cord-254436-89zf41xr 83 1 Regarding regard VBG cord-254436-89zf41xr 83 2 Obesity obesity NN cord-254436-89zf41xr 83 3 as as IN cord-254436-89zf41xr 83 4 a a DT cord-254436-89zf41xr 83 5 Disease Disease NNP cord-254436-89zf41xr 83 6 : : : cord-254436-89zf41xr 84 1 Evolving evolve VBG cord-254436-89zf41xr 84 2 Policies policy NNS cord-254436-89zf41xr 84 3 and and CC cord-254436-89zf41xr 84 4 Their -PRON- PRP$ cord-254436-89zf41xr 84 5 Implications implication NNS cord-254436-89zf41xr 84 6 Is be VBZ cord-254436-89zf41xr 84 7 ethnicity ethnicity NN cord-254436-89zf41xr 84 8 linked link VBN cord-254436-89zf41xr 84 9 to to IN cord-254436-89zf41xr 84 10 incidence incidence NN cord-254436-89zf41xr 84 11 or or CC cord-254436-89zf41xr 84 12 outcomes outcome NNS cord-254436-89zf41xr 84 13 of of IN cord-254436-89zf41xr 84 14 covid-19 covid-19 CD cord-254436-89zf41xr 84 15 ? ? . cord-254436-89zf41xr 84 16 ACE2 ACE2 NNP cord-254436-89zf41xr 84 17 as as IN cord-254436-89zf41xr 84 18 a a DT cord-254436-89zf41xr 84 19 Therapeutic Therapeutic NNP cord-254436-89zf41xr 84 20 Target Target NNP cord-254436-89zf41xr 84 21 for for IN cord-254436-89zf41xr 84 22 COVID-19 COVID-19 NNP cord-254436-89zf41xr 84 23 ; ; : cord-254436-89zf41xr 84 24 its -PRON- PRP$ cord-254436-89zf41xr 84 25 Role role NN cord-254436-89zf41xr 84 26 in in IN cord-254436-89zf41xr 84 27 Infectious Infectious NNP cord-254436-89zf41xr 84 28 Processes Processes NNPS cord-254436-89zf41xr 84 29 and and CC cord-254436-89zf41xr 84 30 Regulation regulation NN cord-254436-89zf41xr 84 31 by by IN cord-254436-89zf41xr 84 32 Modulators modulator NNS cord-254436-89zf41xr 84 33 of of IN cord-254436-89zf41xr 84 34 the the DT cord-254436-89zf41xr 84 35 RAAS RAAS NNP cord-254436-89zf41xr 84 36 System System NNP cord-254436-89zf41xr 84 37 Effect Effect NNP cord-254436-89zf41xr 84 38 of of IN cord-254436-89zf41xr 84 39 Renin Renin NNP cord-254436-89zf41xr 84 40 - - HYPH cord-254436-89zf41xr 84 41 Angiotensin Angiotensin NNP cord-254436-89zf41xr 84 42 - - HYPH cord-254436-89zf41xr 84 43 Aldosterone Aldosterone NNP cord-254436-89zf41xr 84 44 System System NNP cord-254436-89zf41xr 84 45 Inhibitors Inhibitors NNP cord-254436-89zf41xr 84 46 in in IN cord-254436-89zf41xr 84 47 Patients patient NNS cord-254436-89zf41xr 84 48 with with IN cord-254436-89zf41xr 84 49 COVID-19 COVID-19 NNP cord-254436-89zf41xr 84 50 : : : cord-254436-89zf41xr 84 51 a a DT cord-254436-89zf41xr 84 52 Systematic Systematic NNP cord-254436-89zf41xr 84 53 Review Review NNP cord-254436-89zf41xr 84 54 and and CC cord-254436-89zf41xr 84 55 Meta Meta NNP cord-254436-89zf41xr 84 56 - - HYPH cord-254436-89zf41xr 84 57 analysis analysis NN cord-254436-89zf41xr 84 58 of of IN cord-254436-89zf41xr 84 59 28 28 CD cord-254436-89zf41xr 84 60 COVID-19 COVID-19 NNP cord-254436-89zf41xr 84 61 cytokine cytokine NN cord-254436-89zf41xr 84 62 storm storm NN cord-254436-89zf41xr 84 63 : : : cord-254436-89zf41xr 85 1 the the DT cord-254436-89zf41xr 85 2 interplay interplay NN cord-254436-89zf41xr 85 3 between between IN cord-254436-89zf41xr 85 4 inflammation inflammation NN cord-254436-89zf41xr 85 5 and and CC cord-254436-89zf41xr 85 6 coagulation coagulation NN cord-254436-89zf41xr 85 7 Emerging emerge VBG cord-254436-89zf41xr 85 8 evidence evidence NN cord-254436-89zf41xr 85 9 of of IN cord-254436-89zf41xr 85 10 a a DT cord-254436-89zf41xr 85 11 COVID-19 covid-19 JJ cord-254436-89zf41xr 85 12 thrombotic thrombotic JJ cord-254436-89zf41xr 85 13 syndrome syndrome NN cord-254436-89zf41xr 85 14 has have VBZ cord-254436-89zf41xr 85 15 treatment treatment NN cord-254436-89zf41xr 85 16 implications implication NNS cord-254436-89zf41xr 86 1 The the DT cord-254436-89zf41xr 86 2 author author NN cord-254436-89zf41xr 86 3 has have VBZ cord-254436-89zf41xr 86 4 no no DT cord-254436-89zf41xr 86 5 conflict conflict NN cord-254436-89zf41xr 86 6 of of IN cord-254436-89zf41xr 86 7 interest interest NN cord-254436-89zf41xr 86 8 to to TO cord-254436-89zf41xr 86 9 declare declare VB cord-254436-89zf41xr 86 10 . . . cord-254436-89zf41xr 87 1 He -PRON- PRP cord-254436-89zf41xr 87 2 is be VBZ cord-254436-89zf41xr 87 3 the the DT cord-254436-89zf41xr 87 4 President President NNP cord-254436-89zf41xr 87 5 of of IN cord-254436-89zf41xr 87 6 the the DT cord-254436-89zf41xr 87 7 Fellowship Fellowship NNP cord-254436-89zf41xr 87 8 of of IN cord-254436-89zf41xr 87 9 Postgraduate Postgraduate NNP cord-254436-89zf41xr 87 10 Medicine Medicine NNP cord-254436-89zf41xr 87 11 , , , cord-254436-89zf41xr 87 12 for for IN cord-254436-89zf41xr 87 13 which which WDT cord-254436-89zf41xr 87 14 Health Health NNP cord-254436-89zf41xr 87 15 Policy Policy NNP cord-254436-89zf41xr 87 16 and and CC cord-254436-89zf41xr 87 17 Technology Technology NNP cord-254436-89zf41xr 87 18 is be VBZ cord-254436-89zf41xr 87 19 an an DT cord-254436-89zf41xr 87 20 official official JJ cord-254436-89zf41xr 87 21 journal journal NN cord-254436-89zf41xr 87 22 . . . cord-254436-89zf41xr 88 1 During during IN cord-254436-89zf41xr 88 2 2014 2014 CD cord-254436-89zf41xr 88 3 he -PRON- PRP cord-254436-89zf41xr 88 4 was be VBD cord-254436-89zf41xr 88 5 a a DT cord-254436-89zf41xr 88 6 physician physician NN cord-254436-89zf41xr 88 7 and and CC cord-254436-89zf41xr 88 8 pharmacologist pharmacologist NN cord-254436-89zf41xr 88 9 in in IN cord-254436-89zf41xr 88 10 Rwanda Rwanda NNP cord-254436-89zf41xr 88 11 within within IN cord-254436-89zf41xr 88 12 the the DT cord-254436-89zf41xr 88 13 US US NNP cord-254436-89zf41xr 88 14 AID aid NN cord-254436-89zf41xr 88 15 and and CC cord-254436-89zf41xr 88 16 US US NNP cord-254436-89zf41xr 88 17 CDC CDC NNP cord-254436-89zf41xr 88 18 Human Human NNP cord-254436-89zf41xr 88 19 Resources Resources NNPS cord-254436-89zf41xr 88 20 for for IN cord-254436-89zf41xr 88 21 Health Health NNP cord-254436-89zf41xr 88 22 Program Program NNP cord-254436-89zf41xr 88 23 . . .