id	sid	tid	token	lemma	pos
cord-254419-qw83atrx	1	1	key	key	JJ
cord-254419-qw83atrx	1	2	:	:	:
cord-254419-qw83atrx	1	3	cord-254419-qw83atrx	cord-254419-qw83atrx	JJ
cord-254419-qw83atrx	1	4	authors	author	NNS
cord-254419-qw83atrx	1	5	:	:	:
cord-254419-qw83atrx	1	6	Bhattacharyya	Bhattacharyya	NNP
cord-254419-qw83atrx	1	7	,	,	,
cord-254419-qw83atrx	1	8	Rajat	Rajat	NNP
cord-254419-qw83atrx	1	9	;	;	:
cord-254419-qw83atrx	1	10	Iyer	Iyer	NNP
cord-254419-qw83atrx	1	11	,	,	,
cord-254419-qw83atrx	1	12	Prasad	Prasad	NNP
cord-254419-qw83atrx	1	13	;	;	:
cord-254419-qw83atrx	1	14	Phua	Phua	NNP
cord-254419-qw83atrx	1	15	,	,	,
cord-254419-qw83atrx	1	16	Ghee	Ghee	NNP
cord-254419-qw83atrx	1	17	Chee	Chee	NNP
cord-254419-qw83atrx	1	18	;	;	:
cord-254419-qw83atrx	1	19	Lee	Lee	NNP
cord-254419-qw83atrx	1	20	,	,	,
cord-254419-qw83atrx	1	21	Jan	Jan	NNP
cord-254419-qw83atrx	1	22	Hau	Hau	NNP
cord-254419-qw83atrx	1	23	title	title	NN
cord-254419-qw83atrx	1	24	:	:	:
cord-254419-qw83atrx	1	25	The	the	DT
cord-254419-qw83atrx	1	26	Interplay	Interplay	NNP
cord-254419-qw83atrx	1	27	Between	between	IN
cord-254419-qw83atrx	1	28	Coagulation	coagulation	NN
cord-254419-qw83atrx	1	29	and	and	CC
cord-254419-qw83atrx	1	30	Inflammation	inflammation	NN
cord-254419-qw83atrx	1	31	Pathways	pathway	NNS
cord-254419-qw83atrx	1	32	in	in	IN
cord-254419-qw83atrx	1	33	COVID-19-Associated	COVID-19-Associated	NNP
cord-254419-qw83atrx	1	34	Respiratory	Respiratory	NNP
cord-254419-qw83atrx	1	35	Failure	failure	NN
cord-254419-qw83atrx	1	36	:	:	:
cord-254419-qw83atrx	1	37	A	a	DT
cord-254419-qw83atrx	1	38	Narrative	Narrative	NNP
cord-254419-qw83atrx	1	39	Review	Review	NNP
cord-254419-qw83atrx	1	40	date	date	NN
cord-254419-qw83atrx	1	41	:	:	:
cord-254419-qw83atrx	1	42	2020	2020	CD
cord-254419-qw83atrx	1	43	-	-	HYPH
cord-254419-qw83atrx	1	44	08	08	CD
cord-254419-qw83atrx	1	45	-	-	SYM
cord-254419-qw83atrx	1	46	25	25	CD
cord-254419-qw83atrx	1	47	journal	journal	NN
cord-254419-qw83atrx	1	48	:	:	:
cord-254419-qw83atrx	2	1	Pulm	Pulm	NNP
cord-254419-qw83atrx	3	1	Ther	ther	JJ
cord-254419-qw83atrx	3	2	DOI	DOI	NNP
cord-254419-qw83atrx	3	3	:	:	:
cord-254419-qw83atrx	3	4	10.1007	10.1007	CD
cord-254419-qw83atrx	3	5	/	/	SYM
cord-254419-qw83atrx	3	6	s41030	s41030	NN
cord-254419-qw83atrx	3	7	-	-	HYPH
cord-254419-qw83atrx	3	8	020	020	CD
cord-254419-qw83atrx	3	9	-	-	HYPH
cord-254419-qw83atrx	3	10	00126	00126	CD
cord-254419-qw83atrx	3	11	-	-	SYM
cord-254419-qw83atrx	3	12	5	5	CD
cord-254419-qw83atrx	4	1	sha	sha	NNP
cord-254419-qw83atrx	4	2	:	:	:
cord-254419-qw83atrx	5	1	94f1bcf03e009e7f4e08b29adf5aba64ce4b11de	94f1bcf03e009e7f4e08b29adf5aba64ce4b11de	CD
cord-254419-qw83atrx	5	2	doc_id	doc_id	CD
cord-254419-qw83atrx	5	3	:	:	:
cord-254419-qw83atrx	5	4	254419	254419	CD
cord-254419-qw83atrx	5	5	cord_uid	cord_uid	NNS
cord-254419-qw83atrx	5	6	:	:	:
cord-254419-qw83atrx	5	7	qw83atrx	qw83atrx	NNP
cord-254419-qw83atrx	5	8	The	the	DT
cord-254419-qw83atrx	5	9	novel	novel	JJ
cord-254419-qw83atrx	5	10	coronavirus	coronavirus	NN
cord-254419-qw83atrx	5	11	disease	disease	NN
cord-254419-qw83atrx	5	12	(	(	-LRB-
cord-254419-qw83atrx	5	13	COVID-19	covid-19	VB
cord-254419-qw83atrx	5	14	)	)	-RRB-
cord-254419-qw83atrx	5	15	pandemic	pandemic	NN
cord-254419-qw83atrx	5	16	has	have	VBZ
cord-254419-qw83atrx	5	17	caused	cause	VBN
cord-254419-qw83atrx	5	18	an	an	DT
cord-254419-qw83atrx	5	19	unprecedented	unprecedented	JJ
cord-254419-qw83atrx	5	20	worldwide	worldwide	JJ
cord-254419-qw83atrx	5	21	socio	socio	JJ
cord-254419-qw83atrx	5	22	-	-	HYPH
cord-254419-qw83atrx	5	23	economic	economic	JJ
cord-254419-qw83atrx	5	24	and	and	CC
cord-254419-qw83atrx	5	25	health	health	NN
cord-254419-qw83atrx	5	26	impact	impact	NN
cord-254419-qw83atrx	5	27	.	.	.
cord-254419-qw83atrx	6	1	There	there	EX
cord-254419-qw83atrx	6	2	is	be	VBZ
cord-254419-qw83atrx	6	3	increasing	increase	VBG
cord-254419-qw83atrx	6	4	evidence	evidence	NN
cord-254419-qw83atrx	6	5	that	that	IN
cord-254419-qw83atrx	6	6	a	a	DT
cord-254419-qw83atrx	6	7	combination	combination	NN
cord-254419-qw83atrx	6	8	of	of	IN
cord-254419-qw83atrx	6	9	inflammation	inflammation	NN
cord-254419-qw83atrx	6	10	and	and	CC
cord-254419-qw83atrx	6	11	hypercoagulable	hypercoagulable	JJ
cord-254419-qw83atrx	6	12	state	state	NN
cord-254419-qw83atrx	6	13	are	be	VBP
cord-254419-qw83atrx	6	14	the	the	DT
cord-254419-qw83atrx	6	15	main	main	JJ
cord-254419-qw83atrx	6	16	mechanisms	mechanism	NNS
cord-254419-qw83atrx	6	17	of	of	IN
cord-254419-qw83atrx	6	18	respiratory	respiratory	JJ
cord-254419-qw83atrx	6	19	failure	failure	NN
cord-254419-qw83atrx	6	20	in	in	IN
cord-254419-qw83atrx	6	21	these	these	DT
cord-254419-qw83atrx	6	22	patients	patient	NNS
cord-254419-qw83atrx	6	23	.	.	.
cord-254419-qw83atrx	7	1	This	this	DT
cord-254419-qw83atrx	7	2	narrative	narrative	NN
cord-254419-qw83atrx	7	3	review	review	NN
cord-254419-qw83atrx	7	4	aims	aim	VBZ
cord-254419-qw83atrx	7	5	to	to	TO
cord-254419-qw83atrx	7	6	summarize	summarize	VB
cord-254419-qw83atrx	7	7	currently	currently	RB
cord-254419-qw83atrx	7	8	available	available	JJ
cord-254419-qw83atrx	7	9	evidence	evidence	NN
cord-254419-qw83atrx	7	10	on	on	IN
cord-254419-qw83atrx	7	11	the	the	DT
cord-254419-qw83atrx	7	12	complex	complex	JJ
cord-254419-qw83atrx	7	13	interplay	interplay	NN
cord-254419-qw83atrx	7	14	of	of	IN
cord-254419-qw83atrx	7	15	immune	immune	JJ
cord-254419-qw83atrx	7	16	dysregulation	dysregulation	NN
cord-254419-qw83atrx	7	17	,	,	,
cord-254419-qw83atrx	7	18	hypercoagulability	hypercoagulability	NN
cord-254419-qw83atrx	7	19	,	,	,
cord-254419-qw83atrx	7	20	and	and	CC
cord-254419-qw83atrx	7	21	thrombosis	thrombosis	NN
cord-254419-qw83atrx	7	22	in	in	IN
cord-254419-qw83atrx	7	23	the	the	DT
cord-254419-qw83atrx	7	24	pathogenesis	pathogenesis	NN
cord-254419-qw83atrx	7	25	of	of	IN
cord-254419-qw83atrx	7	26	respiratory	respiratory	JJ
cord-254419-qw83atrx	7	27	failure	failure	NN
cord-254419-qw83atrx	7	28	in	in	IN
cord-254419-qw83atrx	7	29	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	7	30	disease	disease	NN
cord-254419-qw83atrx	7	31	.	.	.
cord-254419-qw83atrx	8	1	In	in	IN
cord-254419-qw83atrx	8	2	addition	addition	NN
cord-254419-qw83atrx	8	3	,	,	,
cord-254419-qw83atrx	8	4	we	-PRON-	PRP
cord-254419-qw83atrx	8	5	will	will	MD
cord-254419-qw83atrx	8	6	describe	describe	VB
cord-254419-qw83atrx	8	7	the	the	DT
cord-254419-qw83atrx	8	8	experience	experience	NN
cord-254419-qw83atrx	8	9	of	of	IN
cord-254419-qw83atrx	8	10	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	8	11	and	and	CC
cord-254419-qw83atrx	8	12	anti	anti	JJ
cord-254419-qw83atrx	8	13	-	-	JJ
cord-254419-qw83atrx	8	14	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	8	15	strategies	strategy	NNS
cord-254419-qw83atrx	8	16	that	that	WDT
cord-254419-qw83atrx	8	17	have	have	VBP
cord-254419-qw83atrx	8	18	been	be	VBN
cord-254419-qw83atrx	8	19	tested	test	VBN
cord-254419-qw83atrx	8	20	.	.	.
cord-254419-qw83atrx	9	1	Profound	profound	JJ
cord-254419-qw83atrx	9	2	suppression	suppression	NN
cord-254419-qw83atrx	9	3	of	of	IN
cord-254419-qw83atrx	9	4	the	the	DT
cord-254419-qw83atrx	9	5	adaptive	adaptive	JJ
cord-254419-qw83atrx	9	6	and	and	CC
cord-254419-qw83atrx	9	7	hyperactivity	hyperactivity	NN
cord-254419-qw83atrx	9	8	of	of	IN
cord-254419-qw83atrx	9	9	innate	innate	JJ
cord-254419-qw83atrx	9	10	immune	immune	JJ
cord-254419-qw83atrx	9	11	systems	system	NNS
cord-254419-qw83atrx	9	12	with	with	IN
cord-254419-qw83atrx	9	13	macrophage	macrophage	NN
cord-254419-qw83atrx	9	14	activation	activation	NN
cord-254419-qw83atrx	9	15	appears	appear	VBZ
cord-254419-qw83atrx	9	16	to	to	TO
cord-254419-qw83atrx	9	17	be	be	VB
cord-254419-qw83atrx	9	18	a	a	DT
cord-254419-qw83atrx	9	19	prominent	prominent	JJ
cord-254419-qw83atrx	9	20	feature	feature	NN
cord-254419-qw83atrx	9	21	in	in	IN
cord-254419-qw83atrx	9	22	this	this	DT
cord-254419-qw83atrx	9	23	infection	infection	NN
cord-254419-qw83atrx	9	24	.	.	.
cord-254419-qw83atrx	10	1	Immune	immune	JJ
cord-254419-qw83atrx	10	2	dysregulation	dysregulation	NN
cord-254419-qw83atrx	10	3	together	together	RB
cord-254419-qw83atrx	10	4	with	with	IN
cord-254419-qw83atrx	10	5	endotheliitis	endotheliitis	NN
cord-254419-qw83atrx	10	6	and	and	CC
cord-254419-qw83atrx	10	7	severe	severe	JJ
cord-254419-qw83atrx	10	8	hypercoagulability	hypercoagulability	NN
cord-254419-qw83atrx	10	9	results	result	NNS
cord-254419-qw83atrx	10	10	in	in	IN
cord-254419-qw83atrx	10	11	thromboinflammation	thromboinflammation	NN
cord-254419-qw83atrx	10	12	and	and	CC
cord-254419-qw83atrx	10	13	microvascular	microvascular	JJ
cord-254419-qw83atrx	10	14	thrombosis	thrombosis	NN
cord-254419-qw83atrx	10	15	in	in	IN
cord-254419-qw83atrx	10	16	the	the	DT
cord-254419-qw83atrx	10	17	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	10	18	vasculature	vasculature	NN
cord-254419-qw83atrx	10	19	leading	lead	VBG
cord-254419-qw83atrx	10	20	to	to	IN
cord-254419-qw83atrx	10	21	severe	severe	JJ
cord-254419-qw83atrx	10	22	respiratory	respiratory	JJ
cord-254419-qw83atrx	10	23	distress	distress	NN
cord-254419-qw83atrx	10	24	.	.	.
cord-254419-qw83atrx	11	1	Currently	currently	RB
cord-254419-qw83atrx	11	2	,	,	,
cord-254419-qw83atrx	11	3	some	some	DT
cord-254419-qw83atrx	11	4	guidelines	guideline	NNS
cord-254419-qw83atrx	11	5	recommend	recommend	VBP
cord-254419-qw83atrx	11	6	the	the	DT
cord-254419-qw83atrx	11	7	use	use	NN
cord-254419-qw83atrx	11	8	of	of	IN
cord-254419-qw83atrx	11	9	prophylactic	prophylactic	JJ
cord-254419-qw83atrx	11	10	low	low	JJ
cord-254419-qw83atrx	11	11	molecular	molecular	JJ
cord-254419-qw83atrx	11	12	weight	weight	NN
cord-254419-qw83atrx	11	13	heparin	heparin	JJ
cord-254419-qw83atrx	11	14	in	in	IN
cord-254419-qw83atrx	11	15	all	all	DT
cord-254419-qw83atrx	11	16	hospitalized	hospitalize	VBN
cord-254419-qw83atrx	11	17	patients	patient	NNS
cord-254419-qw83atrx	11	18	,	,	,
cord-254419-qw83atrx	11	19	with	with	IN
cord-254419-qw83atrx	11	20	intermediate	intermediate	JJ
cord-254419-qw83atrx	11	21	dose	dose	NN
cord-254419-qw83atrx	11	22	prophylaxis	prophylaxis	NN
cord-254419-qw83atrx	11	23	in	in	IN
cord-254419-qw83atrx	11	24	those	those	DT
cord-254419-qw83atrx	11	25	needing	need	VBG
cord-254419-qw83atrx	11	26	intensive	intensive	JJ
cord-254419-qw83atrx	11	27	care	care	NN
cord-254419-qw83atrx	11	28	,	,	,
cord-254419-qw83atrx	11	29	and	and	CC
cord-254419-qw83atrx	11	30	the	the	DT
cord-254419-qw83atrx	11	31	use	use	NN
cord-254419-qw83atrx	11	32	of	of	IN
cord-254419-qw83atrx	11	33	therapeutic	therapeutic	JJ
cord-254419-qw83atrx	11	34	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	11	35	in	in	IN
cord-254419-qw83atrx	11	36	patients	patient	NNS
cord-254419-qw83atrx	11	37	with	with	IN
cord-254419-qw83atrx	11	38	proven	prove	VBN
cord-254419-qw83atrx	11	39	or	or	CC
cord-254419-qw83atrx	11	40	suspected	suspect	VBN
cord-254419-qw83atrx	11	41	thrombosis	thrombosis	NN
cord-254419-qw83atrx	11	42	.	.	.
cord-254419-qw83atrx	12	1	Strong	strong	JJ
cord-254419-qw83atrx	12	2	recommendations	recommendation	NNS
cord-254419-qw83atrx	12	3	can	can	MD
cord-254419-qw83atrx	12	4	not	not	RB
cord-254419-qw83atrx	12	5	be	be	VB
cord-254419-qw83atrx	12	6	made	make	VBN
cord-254419-qw83atrx	12	7	until	until	IN
cord-254419-qw83atrx	12	8	this	this	DT
cord-254419-qw83atrx	12	9	approach	approach	NN
cord-254419-qw83atrx	12	10	is	be	VBZ
cord-254419-qw83atrx	12	11	validated	validate	VBN
cord-254419-qw83atrx	12	12	by	by	IN
cord-254419-qw83atrx	12	13	trial	trial	NN
cord-254419-qw83atrx	12	14	results	result	NNS
cord-254419-qw83atrx	12	15	.	.	.
cord-254419-qw83atrx	13	1	To	to	TO
cord-254419-qw83atrx	13	2	target	target	VB
cord-254419-qw83atrx	13	3	the	the	DT
cord-254419-qw83atrx	13	4	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	13	5	cascade	cascade	NN
cord-254419-qw83atrx	13	6	,	,	,
cord-254419-qw83atrx	13	7	low	low	JJ
cord-254419-qw83atrx	13	8	-	-	HYPH
cord-254419-qw83atrx	13	9	dose	dose	NN
cord-254419-qw83atrx	13	10	dexamethasone	dexamethasone	NN
cord-254419-qw83atrx	13	11	appears	appear	VBZ
cord-254419-qw83atrx	13	12	to	to	TO
cord-254419-qw83atrx	13	13	be	be	VB
cord-254419-qw83atrx	13	14	helpful	helpful	JJ
cord-254419-qw83atrx	13	15	in	in	IN
cord-254419-qw83atrx	13	16	moderate	moderate	JJ
cord-254419-qw83atrx	13	17	to	to	IN
cord-254419-qw83atrx	13	18	severe	severe	JJ
cord-254419-qw83atrx	13	19	cases	case	NNS
cord-254419-qw83atrx	13	20	and	and	CC
cord-254419-qw83atrx	13	21	trials	trial	NNS
cord-254419-qw83atrx	13	22	with	with	IN
cord-254419-qw83atrx	13	23	anti	anti	JJ
cord-254419-qw83atrx	13	24	-	-	JJ
cord-254419-qw83atrx	13	25	interleukin	interleukin	JJ
cord-254419-qw83atrx	13	26	agents	agent	NNS
cord-254419-qw83atrx	13	27	(	(	-LRB-
cord-254419-qw83atrx	13	28	e.g.	e.g.	RB
cord-254419-qw83atrx	13	29	,	,	,
cord-254419-qw83atrx	13	30	tocilizumab	tocilizumab	NNP
cord-254419-qw83atrx	13	31	,	,	,
cord-254419-qw83atrx	13	32	anakinra	anakinra	NNP
cord-254419-qw83atrx	13	33	,	,	,
cord-254419-qw83atrx	13	34	siltuximab	siltuximab	NNP
cord-254419-qw83atrx	13	35	)	)	-RRB-
cord-254419-qw83atrx	13	36	and	and	CC
cord-254419-qw83atrx	13	37	non	non	JJ
cord-254419-qw83atrx	13	38	-	-	JJ
cord-254419-qw83atrx	13	39	steroidal	steroidal	JJ
cord-254419-qw83atrx	13	40	anti	anti	JJ
cord-254419-qw83atrx	13	41	-	-	JJ
cord-254419-qw83atrx	13	42	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	13	43	drugs	drug	NNS
cord-254419-qw83atrx	13	44	are	be	VBP
cord-254419-qw83atrx	13	45	showing	show	VBG
cord-254419-qw83atrx	13	46	early	early	JJ
cord-254419-qw83atrx	13	47	promising	promising	JJ
cord-254419-qw83atrx	13	48	results	result	NNS
cord-254419-qw83atrx	13	49	.	.	.
cord-254419-qw83atrx	14	1	Potential	potential	JJ
cord-254419-qw83atrx	14	2	newer	new	JJR
cord-254419-qw83atrx	14	3	agents	agent	NNS
cord-254419-qw83atrx	14	4	(	(	-LRB-
cord-254419-qw83atrx	14	5	e.g.	e.g.	RB
cord-254419-qw83atrx	14	6	,	,	,
cord-254419-qw83atrx	14	7	Janus	Janus	NNP
cord-254419-qw83atrx	14	8	kinase	kinase	NN
cord-254419-qw83atrx	14	9	inhibitor	inhibitor	NN
cord-254419-qw83atrx	14	10	such	such	JJ
cord-254419-qw83atrx	14	11	as	as	IN
cord-254419-qw83atrx	14	12	ruxolitinib	ruxolitinib	NNP
cord-254419-qw83atrx	14	13	,	,	,
cord-254419-qw83atrx	14	14	baricitinib	baricitinib	NNP
cord-254419-qw83atrx	14	15	,	,	,
cord-254419-qw83atrx	14	16	fedratinib	fedratinib	NNP
cord-254419-qw83atrx	14	17	)	)	-RRB-
cord-254419-qw83atrx	14	18	are	be	VBP
cord-254419-qw83atrx	14	19	likely	likely	JJ
cord-254419-qw83atrx	14	20	to	to	TO
cord-254419-qw83atrx	14	21	be	be	VB
cord-254419-qw83atrx	14	22	investigated	investigate	VBN
cord-254419-qw83atrx	14	23	in	in	IN
cord-254419-qw83atrx	14	24	clinical	clinical	JJ
cord-254419-qw83atrx	14	25	trials	trial	NNS
cord-254419-qw83atrx	14	26	.	.	.
cord-254419-qw83atrx	15	1	Unfortunately	unfortunately	RB
cord-254419-qw83atrx	15	2	,	,	,
cord-254419-qw83atrx	15	3	current	current	JJ
cord-254419-qw83atrx	15	4	trials	trial	NNS
cord-254419-qw83atrx	15	5	are	be	VBP
cord-254419-qw83atrx	15	6	mostly	mostly	RB
cord-254419-qw83atrx	15	7	examining	examine	VBG
cord-254419-qw83atrx	15	8	these	these	DT
cord-254419-qw83atrx	15	9	agents	agent	NNS
cord-254419-qw83atrx	15	10	in	in	IN
cord-254419-qw83atrx	15	11	isolation	isolation	NN
cord-254419-qw83atrx	15	12	and	and	CC
cord-254419-qw83atrx	15	13	there	there	EX
cord-254419-qw83atrx	15	14	may	may	MD
cord-254419-qw83atrx	15	15	be	be	VB
cord-254419-qw83atrx	15	16	a	a	DT
cord-254419-qw83atrx	15	17	significant	significant	JJ
cord-254419-qw83atrx	15	18	delay	delay	NN
cord-254419-qw83atrx	15	19	before	before	IN
cord-254419-qw83atrx	15	20	evidence	evidence	NN
cord-254419-qw83atrx	15	21	-	-	HYPH
cord-254419-qw83atrx	15	22	based	base	VBN
cord-254419-qw83atrx	15	23	practice	practice	NN
cord-254419-qw83atrx	15	24	can	can	MD
cord-254419-qw83atrx	15	25	be	be	VB
cord-254419-qw83atrx	15	26	implemented	implement	VBN
cord-254419-qw83atrx	15	27	.	.	.
cord-254419-qw83atrx	16	1	It	-PRON-	PRP
cord-254419-qw83atrx	16	2	is	be	VBZ
cord-254419-qw83atrx	16	3	plausible	plausible	JJ
cord-254419-qw83atrx	16	4	that	that	IN
cord-254419-qw83atrx	16	5	a	a	DT
cord-254419-qw83atrx	16	6	combination	combination	NN
cord-254419-qw83atrx	16	7	of	of	IN
cord-254419-qw83atrx	16	8	anti	anti	JJ
cord-254419-qw83atrx	16	9	-	-	JJ
cord-254419-qw83atrx	16	10	viral	viral	JJ
cord-254419-qw83atrx	16	11	drugs	drug	NNS
cord-254419-qw83atrx	16	12	together	together	RB
cord-254419-qw83atrx	16	13	with	with	IN
cord-254419-qw83atrx	16	14	anti	anti	JJ
cord-254419-qw83atrx	16	15	-	-	JJ
cord-254419-qw83atrx	16	16	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	16	17	and	and	CC
cord-254419-qw83atrx	16	18	anti	anti	JJ
cord-254419-qw83atrx	16	19	-	-	JJ
cord-254419-qw83atrx	16	20	coagulation	coagulation	JJ
cord-254419-qw83atrx	16	21	medicines	medicine	NNS
cord-254419-qw83atrx	16	22	will	will	MD
cord-254419-qw83atrx	16	23	be	be	VB
cord-254419-qw83atrx	16	24	the	the	DT
cord-254419-qw83atrx	16	25	most	most	RBS
cord-254419-qw83atrx	16	26	successful	successful	JJ
cord-254419-qw83atrx	16	27	strategy	strategy	NN
cord-254419-qw83atrx	16	28	in	in	IN
cord-254419-qw83atrx	16	29	managing	manage	VBG
cord-254419-qw83atrx	16	30	severely	severely	RB
cord-254419-qw83atrx	16	31	affected	affect	VBN
cord-254419-qw83atrx	16	32	patients	patient	NNS
cord-254419-qw83atrx	16	33	with	with	IN
cord-254419-qw83atrx	16	34	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	16	35	.	.	.
cord-254419-qw83atrx	17	1	suppression	suppression	NN
cord-254419-qw83atrx	17	2	of	of	IN
cord-254419-qw83atrx	17	3	the	the	DT
cord-254419-qw83atrx	17	4	adaptive	adaptive	JJ
cord-254419-qw83atrx	17	5	and	and	CC
cord-254419-qw83atrx	17	6	hyperactivity	hyperactivity	NN
cord-254419-qw83atrx	17	7	of	of	IN
cord-254419-qw83atrx	17	8	innate	innate	JJ
cord-254419-qw83atrx	17	9	immune	immune	JJ
cord-254419-qw83atrx	17	10	systems	system	NNS
cord-254419-qw83atrx	17	11	with	with	IN
cord-254419-qw83atrx	17	12	macrophage	macrophage	NN
cord-254419-qw83atrx	17	13	activation	activation	NN
cord-254419-qw83atrx	17	14	appears	appear	VBZ
cord-254419-qw83atrx	17	15	to	to	TO
cord-254419-qw83atrx	17	16	be	be	VB
cord-254419-qw83atrx	17	17	a	a	DT
cord-254419-qw83atrx	17	18	prominent	prominent	JJ
cord-254419-qw83atrx	17	19	feature	feature	NN
cord-254419-qw83atrx	17	20	in	in	IN
cord-254419-qw83atrx	17	21	this	this	DT
cord-254419-qw83atrx	17	22	infection	infection	NN
cord-254419-qw83atrx	17	23	.	.	.
cord-254419-qw83atrx	18	1	Immune	immune	JJ
cord-254419-qw83atrx	18	2	dysregulation	dysregulation	NN
cord-254419-qw83atrx	18	3	together	together	RB
cord-254419-qw83atrx	18	4	with	with	IN
cord-254419-qw83atrx	18	5	endotheliitis	endotheliitis	NN
cord-254419-qw83atrx	18	6	and	and	CC
cord-254419-qw83atrx	18	7	severe	severe	JJ
cord-254419-qw83atrx	18	8	hypercoagulability	hypercoagulability	NN
cord-254419-qw83atrx	18	9	results	result	NNS
cord-254419-qw83atrx	18	10	in	in	IN
cord-254419-qw83atrx	18	11	thromboinflammation	thromboinflammation	NN
cord-254419-qw83atrx	18	12	and	and	CC
cord-254419-qw83atrx	18	13	microvascular	microvascular	JJ
cord-254419-qw83atrx	18	14	thrombosis	thrombosis	NN
cord-254419-qw83atrx	18	15	in	in	IN
cord-254419-qw83atrx	18	16	the	the	DT
cord-254419-qw83atrx	18	17	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	18	18	vasculature	vasculature	NN
cord-254419-qw83atrx	18	19	leading	lead	VBG
cord-254419-qw83atrx	18	20	to	to	IN
cord-254419-qw83atrx	18	21	severe	severe	JJ
cord-254419-qw83atrx	18	22	respiratory	respiratory	JJ
cord-254419-qw83atrx	18	23	distress	distress	NN
cord-254419-qw83atrx	18	24	.	.	.
cord-254419-qw83atrx	19	1	Currently	currently	RB
cord-254419-qw83atrx	19	2	,	,	,
cord-254419-qw83atrx	19	3	some	some	DT
cord-254419-qw83atrx	19	4	guidelines	guideline	NNS
cord-254419-qw83atrx	19	5	recommend	recommend	VBP
cord-254419-qw83atrx	19	6	the	the	DT
cord-254419-qw83atrx	19	7	use	use	NN
cord-254419-qw83atrx	19	8	of	of	IN
cord-254419-qw83atrx	19	9	prophylactic	prophylactic	JJ
cord-254419-qw83atrx	19	10	low	low	JJ
cord-254419-qw83atrx	19	11	molecular	molecular	JJ
cord-254419-qw83atrx	19	12	weight	weight	NN
cord-254419-qw83atrx	19	13	heparin	heparin	JJ
cord-254419-qw83atrx	19	14	in	in	IN
cord-254419-qw83atrx	19	15	all	all	DT
cord-254419-qw83atrx	19	16	hospitalized	hospitalize	VBN
cord-254419-qw83atrx	19	17	patients	patient	NNS
cord-254419-qw83atrx	19	18	,	,	,
cord-254419-qw83atrx	19	19	with	with	IN
cord-254419-qw83atrx	19	20	intermediate	intermediate	JJ
cord-254419-qw83atrx	19	21	dose	dose	NN
cord-254419-qw83atrx	19	22	prophylaxis	prophylaxis	NN
cord-254419-qw83atrx	19	23	in	in	IN
cord-254419-qw83atrx	19	24	those	those	DT
cord-254419-qw83atrx	19	25	needing	need	VBG
cord-254419-qw83atrx	19	26	intensive	intensive	JJ
cord-254419-qw83atrx	19	27	care	care	NN
cord-254419-qw83atrx	19	28	,	,	,
cord-254419-qw83atrx	19	29	and	and	CC
cord-254419-qw83atrx	19	30	the	the	DT
cord-254419-qw83atrx	19	31	use	use	NN
cord-254419-qw83atrx	19	32	of	of	IN
cord-254419-qw83atrx	19	33	therapeutic	therapeutic	JJ
cord-254419-qw83atrx	19	34	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	19	35	in	in	IN
cord-254419-qw83atrx	19	36	patients	patient	NNS
cord-254419-qw83atrx	19	37	with	with	IN
cord-254419-qw83atrx	19	38	proven	prove	VBN
cord-254419-qw83atrx	19	39	or	or	CC
cord-254419-qw83atrx	19	40	suspected	suspect	VBN
cord-254419-qw83atrx	19	41	thrombosis	thrombosis	NN
cord-254419-qw83atrx	19	42	.	.	.
cord-254419-qw83atrx	20	1	Strong	strong	JJ
cord-254419-qw83atrx	20	2	recommendations	recommendation	NNS
cord-254419-qw83atrx	20	3	can	can	MD
cord-254419-qw83atrx	20	4	not	not	RB
cord-254419-qw83atrx	20	5	be	be	VB
cord-254419-qw83atrx	20	6	made	make	VBN
cord-254419-qw83atrx	20	7	until	until	IN
cord-254419-qw83atrx	20	8	this	this	DT
cord-254419-qw83atrx	20	9	approach	approach	NN
cord-254419-qw83atrx	20	10	is	be	VBZ
cord-254419-qw83atrx	20	11	validated	validate	VBN
cord-254419-qw83atrx	20	12	by	by	IN
cord-254419-qw83atrx	20	13	trial	trial	NN
cord-254419-qw83atrx	20	14	results	result	NNS
cord-254419-qw83atrx	20	15	.	.	.
cord-254419-qw83atrx	21	1	To	to	TO
cord-254419-qw83atrx	21	2	target	target	VB
cord-254419-qw83atrx	21	3	the	the	DT
cord-254419-qw83atrx	21	4	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	21	5	cascade	cascade	NN
cord-254419-qw83atrx	21	6	,	,	,
cord-254419-qw83atrx	21	7	low	low	JJ
cord-254419-qw83atrx	21	8	-	-	HYPH
cord-254419-qw83atrx	21	9	dose	dose	NN
cord-254419-qw83atrx	21	10	dexamethasone	dexamethasone	NN
cord-254419-qw83atrx	21	11	appears	appear	VBZ
cord-254419-qw83atrx	21	12	to	to	TO
cord-254419-qw83atrx	21	13	be	be	VB
cord-254419-qw83atrx	21	14	helpful	helpful	JJ
cord-254419-qw83atrx	21	15	in	in	IN
cord-254419-qw83atrx	21	16	moderate	moderate	JJ
cord-254419-qw83atrx	21	17	to	to	IN
cord-254419-qw83atrx	21	18	severe	severe	JJ
cord-254419-qw83atrx	21	19	cases	case	NNS
cord-254419-qw83atrx	21	20	and	and	CC
cord-254419-qw83atrx	21	21	trials	trial	NNS
cord-254419-qw83atrx	21	22	with	with	IN
cord-254419-qw83atrx	21	23	anti	anti	JJ
cord-254419-qw83atrx	21	24	-	-	JJ
cord-254419-qw83atrx	21	25	interleukin	interleukin	JJ
cord-254419-qw83atrx	21	26	agents	agent	NNS
cord-254419-qw83atrx	21	27	(	(	-LRB-
cord-254419-qw83atrx	21	28	e.g.	e.g.	RB
cord-254419-qw83atrx	21	29	,	,	,
cord-254419-qw83atrx	21	30	tocilizumab	tocilizumab	NNP
cord-254419-qw83atrx	21	31	,	,	,
cord-254419-qw83atrx	21	32	anakinra	anakinra	NNP
cord-254419-qw83atrx	21	33	,	,	,
cord-254419-qw83atrx	21	34	siltuximab	siltuximab	NNP
cord-254419-qw83atrx	21	35	)	)	-RRB-
cord-254419-qw83atrx	21	36	and	and	CC
cord-254419-qw83atrx	21	37	non	non	JJ
cord-254419-qw83atrx	21	38	-	-	JJ
cord-254419-qw83atrx	21	39	steroidal	steroidal	JJ
cord-254419-qw83atrx	21	40	anti	anti	JJ
cord-254419-qw83atrx	21	41	-	-	JJ
cord-254419-qw83atrx	21	42	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	21	43	drugs	drug	NNS
cord-254419-qw83atrx	21	44	are	be	VBP
cord-254419-qw83atrx	21	45	showing	show	VBG
cord-254419-qw83atrx	21	46	early	early	JJ
cord-254419-qw83atrx	21	47	promising	promising	JJ
cord-254419-qw83atrx	21	48	results	result	NNS
cord-254419-qw83atrx	21	49	.	.	.
cord-254419-qw83atrx	22	1	Potential	potential	JJ
cord-254419-qw83atrx	22	2	newer	new	JJR
cord-254419-qw83atrx	22	3	agents	agent	NNS
cord-254419-qw83atrx	22	4	(	(	-LRB-
cord-254419-qw83atrx	22	5	e.g.	e.g.	RB
cord-254419-qw83atrx	22	6	,	,	,
cord-254419-qw83atrx	22	7	Janus	Janus	NNP
cord-254419-qw83atrx	22	8	kinase	kinase	NN
cord-254419-qw83atrx	22	9	inhibitor	inhibitor	NN
cord-254419-qw83atrx	22	10	such	such	JJ
cord-254419-qw83atrx	22	11	as	as	IN
cord-254419-qw83atrx	22	12	ruxolitinib	ruxolitinib	NNP
cord-254419-qw83atrx	22	13	,	,	,
cord-254419-qw83atrx	22	14	baricitinib	baricitinib	NNP
cord-254419-qw83atrx	22	15	,	,	,
cord-254419-qw83atrx	22	16	fedratinib	fedratinib	NNP
cord-254419-qw83atrx	22	17	)	)	-RRB-
cord-254419-qw83atrx	22	18	are	be	VBP
cord-254419-qw83atrx	22	19	likely	likely	JJ
cord-254419-qw83atrx	22	20	to	to	TO
cord-254419-qw83atrx	22	21	be	be	VB
cord-254419-qw83atrx	22	22	investigated	investigate	VBN
cord-254419-qw83atrx	22	23	in	in	IN
cord-254419-qw83atrx	22	24	clinical	clinical	JJ
cord-254419-qw83atrx	22	25	trials	trial	NNS
cord-254419-qw83atrx	22	26	.	.	.
cord-254419-qw83atrx	23	1	Unfortunately	unfortunately	RB
cord-254419-qw83atrx	23	2	,	,	,
cord-254419-qw83atrx	23	3	current	current	JJ
cord-254419-qw83atrx	23	4	trials	trial	NNS
cord-254419-qw83atrx	23	5	are	be	VBP
cord-254419-qw83atrx	23	6	mostly	mostly	RB
cord-254419-qw83atrx	23	7	examining	examine	VBG
cord-254419-qw83atrx	23	8	these	these	DT
cord-254419-qw83atrx	23	9	agents	agent	NNS
cord-254419-qw83atrx	23	10	in	in	IN
cord-254419-qw83atrx	23	11	isolation	isolation	NN
cord-254419-qw83atrx	23	12	and	and	CC
cord-254419-qw83atrx	23	13	there	there	EX
cord-254419-qw83atrx	23	14	may	may	MD
cord-254419-qw83atrx	23	15	be	be	VB
cord-254419-qw83atrx	23	16	a	a	DT
cord-254419-qw83atrx	23	17	significant	significant	JJ
cord-254419-qw83atrx	23	18	delay	delay	NN
cord-254419-qw83atrx	23	19	before	before	IN
cord-254419-qw83atrx	23	20	evidence	evidence	NN
cord-254419-qw83atrx	23	21	-	-	HYPH
cord-254419-qw83atrx	23	22	based	base	VBN
cord-254419-qw83atrx	23	23	practice	practice	NN
cord-254419-qw83atrx	23	24	can	can	MD
cord-254419-qw83atrx	23	25	be	be	VB
cord-254419-qw83atrx	23	26	implemented	implement	VBN
cord-254419-qw83atrx	23	27	.	.	.
cord-254419-qw83atrx	24	1	It	-PRON-	PRP
cord-254419-qw83atrx	24	2	is	be	VBZ
cord-254419-qw83atrx	24	3	plausible	plausible	JJ
cord-254419-qw83atrx	24	4	that	that	IN
cord-254419-qw83atrx	24	5	a	a	DT
cord-254419-qw83atrx	24	6	combination	combination	NN
cord-254419-qw83atrx	24	7	of	of	IN
cord-254419-qw83atrx	24	8	anti	anti	JJ
cord-254419-qw83atrx	24	9	-	-	JJ
cord-254419-qw83atrx	24	10	viral	viral	JJ
cord-254419-qw83atrx	24	11	drugs	drug	NNS
cord-254419-qw83atrx	24	12	together	together	RB
cord-254419-qw83atrx	24	13	with	with	IN
cord-254419-qw83atrx	24	14	anti	anti	JJ
cord-254419-qw83atrx	24	15	-	-	JJ
cord-254419-qw83atrx	24	16	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	24	17	and	and	CC
cord-254419-qw83atrx	24	18	anti	anti	JJ
cord-254419-qw83atrx	24	19	-	-	JJ
cord-254419-qw83atrx	24	20	coagulation	coagulation	JJ
cord-254419-qw83atrx	24	21	medicines	medicine	NNS
cord-254419-qw83atrx	24	22	will	will	MD
cord-254419-qw83atrx	24	23	be	be	VB
cord-254419-qw83atrx	24	24	the	the	DT
cord-254419-qw83atrx	24	25	most	most	RBS
cord-254419-qw83atrx	24	26	successful	successful	JJ
cord-254419-qw83atrx	24	27	strategy	strategy	NN
cord-254419-qw83atrx	24	28	in	in	IN
cord-254419-qw83atrx	24	29	A	a	DT
cord-254419-qw83atrx	24	30	novel	novel	JJ
cord-254419-qw83atrx	24	31	coronavirus	coronavirus	NN
cord-254419-qw83atrx	24	32	infection	infection	NN
cord-254419-qw83atrx	24	33	caused	cause	VBN
cord-254419-qw83atrx	24	34	by	by	IN
cord-254419-qw83atrx	24	35	the	the	DT
cord-254419-qw83atrx	24	36	severe	severe	JJ
cord-254419-qw83atrx	24	37	acute	acute	JJ
cord-254419-qw83atrx	24	38	respiratory	respiratory	JJ
cord-254419-qw83atrx	24	39	syndrome	syndrome	NN
cord-254419-qw83atrx	24	40	coronavirus	coronavirus	NN
cord-254419-qw83atrx	24	41	2	2	CD
cord-254419-qw83atrx	25	1	(	(	-LRB-
cord-254419-qw83atrx	25	2	SARS	SARS	NNP
cord-254419-qw83atrx	25	3	-	-	HYPH
cord-254419-qw83atrx	25	4	CoV-2	CoV-2	NNP
cord-254419-qw83atrx	25	5	)	)	-RRB-
cord-254419-qw83atrx	25	6	,	,	,
cord-254419-qw83atrx	25	7	now	now	RB
cord-254419-qw83atrx	25	8	called	call	VBN
cord-254419-qw83atrx	25	9	Coronavirus	Coronavirus	NNP
cord-254419-qw83atrx	25	10	disease-19	disease-19	NNP
cord-254419-qw83atrx	25	11	,	,	,
cord-254419-qw83atrx	25	12	has	have	VBZ
cord-254419-qw83atrx	25	13	led	lead	VBN
cord-254419-qw83atrx	25	14	to	to	IN
cord-254419-qw83atrx	25	15	a	a	DT
cord-254419-qw83atrx	25	16	global	global	JJ
cord-254419-qw83atrx	25	17	pandemic	pandemic	NN
cord-254419-qw83atrx	25	18	in	in	IN
cord-254419-qw83atrx	25	19	2020	2020	CD
cord-254419-qw83atrx	25	20	.	.	.
cord-254419-qw83atrx	26	1	It	-PRON-	PRP
cord-254419-qw83atrx	26	2	has	have	VBZ
cord-254419-qw83atrx	26	3	affected	affect	VBN
cord-254419-qw83atrx	26	4	10,302,867	10,302,867	CD
cord-254419-qw83atrx	26	5	people	people	NNS
cord-254419-qw83atrx	26	6	worldwide	worldwide	RB
cord-254419-qw83atrx	26	7	with	with	IN
cord-254419-qw83atrx	26	8	505,518	505,518	CD
cord-254419-qw83atrx	26	9	deaths	death	NNS
cord-254419-qw83atrx	26	10	directly	directly	RB
cord-254419-qw83atrx	26	11	attributed	attribute	VBN
cord-254419-qw83atrx	26	12	to	to	IN
cord-254419-qw83atrx	26	13	the	the	DT
cord-254419-qw83atrx	26	14	virus	virus	NN
cord-254419-qw83atrx	26	15	at	at	IN
cord-254419-qw83atrx	26	16	the	the	DT
cord-254419-qw83atrx	26	17	time	time	NN
cord-254419-qw83atrx	26	18	of	of	IN
cord-254419-qw83atrx	26	19	writing	write	VBG
cord-254419-qw83atrx	26	20	this	this	DT
cord-254419-qw83atrx	26	21	paper	paper	NN
cord-254419-qw83atrx	26	22	(	(	-LRB-
cord-254419-qw83atrx	26	23	June	June	NNP
cord-254419-qw83atrx	26	24	30	30	CD
cord-254419-qw83atrx	26	25	,	,	,
cord-254419-qw83atrx	26	26	2020	2020	CD
cord-254419-qw83atrx	26	27	)	)	-RRB-
cord-254419-qw83atrx	26	28	,	,	,
cord-254419-qw83atrx	26	29	and	and	CC
cord-254419-qw83atrx	26	30	the	the	DT
cord-254419-qw83atrx	26	31	rate	rate	NN
cord-254419-qw83atrx	26	32	of	of	IN
cord-254419-qw83atrx	26	33	new	new	JJ
cord-254419-qw83atrx	26	34	infections	infection	NNS
cord-254419-qw83atrx	26	35	continues	continue	VBZ
cord-254419-qw83atrx	26	36	to	to	TO
cord-254419-qw83atrx	26	37	increase	increase	VB
cord-254419-qw83atrx	26	38	at	at	IN
cord-254419-qw83atrx	26	39	a	a	DT
cord-254419-qw83atrx	26	40	very	very	RB
cord-254419-qw83atrx	26	41	fast	fast	JJ
cord-254419-qw83atrx	26	42	pace	pace	NN
cord-254419-qw83atrx	26	43	[	[	-LRB-
cord-254419-qw83atrx	26	44	1	1	CD
cord-254419-qw83atrx	26	45	]	]	-RRB-
cord-254419-qw83atrx	26	46	.	.	.
cord-254419-qw83atrx	27	1	While	while	IN
cord-254419-qw83atrx	27	2	most	most	JJS
cord-254419-qw83atrx	27	3	of	of	IN
cord-254419-qw83atrx	27	4	those	those	DT
cord-254419-qw83atrx	27	5	infected	infect	VBN
cord-254419-qw83atrx	27	6	have	have	VBP
cord-254419-qw83atrx	27	7	mild	mild	JJ
cord-254419-qw83atrx	27	8	cases	case	NNS
cord-254419-qw83atrx	27	9	of	of	IN
cord-254419-qw83atrx	27	10	the	the	DT
cord-254419-qw83atrx	27	11	disease	disease	NN
cord-254419-qw83atrx	27	12	,	,	,
cord-254419-qw83atrx	27	13	up	up	IN
cord-254419-qw83atrx	27	14	to	to	TO
cord-254419-qw83atrx	27	15	14	14	CD
cord-254419-qw83atrx	27	16	%	%	NN
cord-254419-qw83atrx	27	17	can	can	MD
cord-254419-qw83atrx	27	18	have	have	VB
cord-254419-qw83atrx	27	19	a	a	DT
cord-254419-qw83atrx	27	20	severe	severe	JJ
cord-254419-qw83atrx	27	21	clinical	clinical	JJ
cord-254419-qw83atrx	27	22	picture	picture	NN
cord-254419-qw83atrx	27	23	(	(	-LRB-
cord-254419-qw83atrx	27	24	i.e.	i.e.	FW
cord-254419-qw83atrx	27	25	,	,	,
cord-254419-qw83atrx	27	26	dyspnea	dyspnea	NN
cord-254419-qw83atrx	27	27	,	,	,
cord-254419-qw83atrx	27	28	tachypnea	tachypnea	NNP
cord-254419-qw83atrx	27	29	,	,	,
cord-254419-qw83atrx	27	30	hypoxemia	hypoxemia	NN
cord-254419-qw83atrx	27	31	and/or	and/or	CC
cord-254419-qw83atrx	27	32	lung	lung	NN
cord-254419-qw83atrx	27	33	infiltrates	infiltrate	VBZ
cord-254419-qw83atrx	27	34	on	on	IN
cord-254419-qw83atrx	27	35	radiological	radiological	JJ
cord-254419-qw83atrx	27	36	imaging	imaging	NN
cord-254419-qw83atrx	27	37	)	)	-RRB-
cord-254419-qw83atrx	27	38	,	,	,
cord-254419-qw83atrx	27	39	and	and	CC
cord-254419-qw83atrx	27	40	approximately	approximately	RB
cord-254419-qw83atrx	27	41	5	5	CD
cord-254419-qw83atrx	27	42	%	%	NN
cord-254419-qw83atrx	27	43	of	of	IN
cord-254419-qw83atrx	27	44	the	the	DT
cord-254419-qw83atrx	27	45	infected	infected	JJ
cord-254419-qw83atrx	27	46	patients	patient	NNS
cord-254419-qw83atrx	27	47	will	will	MD
cord-254419-qw83atrx	27	48	require	require	VB
cord-254419-qw83atrx	27	49	admission	admission	NN
cord-254419-qw83atrx	27	50	to	to	IN
cord-254419-qw83atrx	27	51	the	the	DT
cord-254419-qw83atrx	27	52	intensive	intensive	JJ
cord-254419-qw83atrx	27	53	care	care	NN
cord-254419-qw83atrx	27	54	unit	unit	NN
cord-254419-qw83atrx	27	55	(	(	-LRB-
cord-254419-qw83atrx	27	56	ICU	ICU	NNP
cord-254419-qw83atrx	27	57	)	)	-RRB-
cord-254419-qw83atrx	27	58	for	for	IN
cord-254419-qw83atrx	27	59	respiratory	respiratory	JJ
cord-254419-qw83atrx	27	60	failure	failure	NN
cord-254419-qw83atrx	27	61	,	,	,
cord-254419-qw83atrx	27	62	septic	septic	JJ
cord-254419-qw83atrx	27	63	shock	shock	NN
cord-254419-qw83atrx	27	64	,	,	,
cord-254419-qw83atrx	27	65	and/	and/	CD
cord-254419-qw83atrx	27	66	or	or	CC
cord-254419-qw83atrx	27	67	multiple	multiple	JJ
cord-254419-qw83atrx	27	68	organ	organ	NN
cord-254419-qw83atrx	27	69	failure	failure	NN
cord-254419-qw83atrx	27	70	[	[	-LRB-
cord-254419-qw83atrx	27	71	2	2	CD
cord-254419-qw83atrx	27	72	]	]	-RRB-
cord-254419-qw83atrx	27	73	.	.	.
cord-254419-qw83atrx	28	1	The	the	DT
cord-254419-qw83atrx	28	2	severe	severe	JJ
cord-254419-qw83atrx	28	3	respiratory	respiratory	JJ
cord-254419-qw83atrx	28	4	failure	failure	NN
cord-254419-qw83atrx	28	5	caused	cause	VBN
cord-254419-qw83atrx	28	6	by	by	IN
cord-254419-qw83atrx	28	7	COVID-19	covid-19	JJ
cord-254419-qw83atrx	28	8	infection	infection	NN
cord-254419-qw83atrx	28	9	results	result	NNS
cord-254419-qw83atrx	28	10	in	in	IN
cord-254419-qw83atrx	28	11	acute	acute	JJ
cord-254419-qw83atrx	28	12	hypoxemia	hypoxemia	NN
cord-254419-qw83atrx	28	13	,	,	,
cord-254419-qw83atrx	28	14	which	which	WDT
cord-254419-qw83atrx	28	15	is	be	VBZ
cord-254419-qw83atrx	28	16	associated	associate	VBN
cord-254419-qw83atrx	28	17	with	with	IN
cord-254419-qw83atrx	28	18	severe	severe	JJ
cord-254419-qw83atrx	28	19	ventilation/	ventilation/	CD
cord-254419-qw83atrx	28	20	perfusion	perfusion	NN
cord-254419-qw83atrx	28	21	(	(	-LRB-
cord-254419-qw83atrx	28	22	V	v	NN
cord-254419-qw83atrx	28	23	/	/	SYM
cord-254419-qw83atrx	28	24	Q	q	NN
cord-254419-qw83atrx	28	25	)	)	-RRB-
cord-254419-qw83atrx	28	26	mismatch	mismatch	NN
cord-254419-qw83atrx	28	27	and	and	CC
cord-254419-qw83atrx	28	28	overt	overt	JJ
cord-254419-qw83atrx	28	29	intrapulmonary	intrapulmonary	JJ
cord-254419-qw83atrx	28	30	shunting	shunt	VBG
cord-254419-qw83atrx	28	31	[	[	-LRB-
cord-254419-qw83atrx	28	32	3	3	CD
cord-254419-qw83atrx	28	33	,	,	,
cord-254419-qw83atrx	28	34	4	4	CD
cord-254419-qw83atrx	28	35	]	]	-RRB-
cord-254419-qw83atrx	28	36	.	.	.
cord-254419-qw83atrx	29	1	However	however	RB
cord-254419-qw83atrx	29	2	,	,	,
cord-254419-qw83atrx	29	3	the	the	DT
cord-254419-qw83atrx	29	4	exact	exact	JJ
cord-254419-qw83atrx	29	5	mechanism	mechanism	NN
cord-254419-qw83atrx	29	6	of	of	IN
cord-254419-qw83atrx	29	7	respiratory	respiratory	JJ
cord-254419-qw83atrx	29	8	failure	failure	NN
cord-254419-qw83atrx	29	9	remains	remain	VBZ
cord-254419-qw83atrx	29	10	unclear	unclear	JJ
cord-254419-qw83atrx	29	11	and	and	CC
cord-254419-qw83atrx	29	12	there	there	EX
cord-254419-qw83atrx	29	13	is	be	VBZ
cord-254419-qw83atrx	29	14	evidence	evidence	NN
cord-254419-qw83atrx	29	15	that	that	IN
cord-254419-qw83atrx	29	16	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	29	17	microvascular	microvascular	JJ
cord-254419-qw83atrx	29	18	thrombosis	thrombosis	NN
cord-254419-qw83atrx	29	19	due	due	IN
cord-254419-qw83atrx	29	20	to	to	IN
cord-254419-qw83atrx	29	21	thrombo	thrombo	NN
cord-254419-qw83atrx	29	22	-	-	HYPH
cord-254419-qw83atrx	29	23	inflammation	inflammation	NN
cord-254419-qw83atrx	29	24	may	may	MD
cord-254419-qw83atrx	29	25	be	be	VB
cord-254419-qw83atrx	29	26	a	a	DT
cord-254419-qw83atrx	29	27	major	major	JJ
cord-254419-qw83atrx	29	28	factor	factor	NN
cord-254419-qw83atrx	29	29	contributing	contribute	VBG
cord-254419-qw83atrx	29	30	to	to	IN
cord-254419-qw83atrx	29	31	respiratory	respiratory	JJ
cord-254419-qw83atrx	29	32	decompensation	decompensation	NN
cord-254419-qw83atrx	29	33	in	in	IN
cord-254419-qw83atrx	29	34	these	these	DT
cord-254419-qw83atrx	29	35	patients	patient	NNS
cord-254419-qw83atrx	29	36	[	[	-LRB-
cord-254419-qw83atrx	29	37	5	5	CD
cord-254419-qw83atrx	29	38	]	]	-RRB-
cord-254419-qw83atrx	29	39	.	.	.
cord-254419-qw83atrx	30	1	This	this	DT
cord-254419-qw83atrx	30	2	narrative	narrative	NN
cord-254419-qw83atrx	30	3	review	review	NN
cord-254419-qw83atrx	30	4	aims	aim	VBZ
cord-254419-qw83atrx	30	5	to	to	TO
cord-254419-qw83atrx	30	6	summarize	summarize	VB
cord-254419-qw83atrx	30	7	the	the	DT
cord-254419-qw83atrx	30	8	current	current	JJ
cord-254419-qw83atrx	30	9	available	available	JJ
cord-254419-qw83atrx	30	10	evidence	evidence	NN
cord-254419-qw83atrx	30	11	on	on	IN
cord-254419-qw83atrx	30	12	the	the	DT
cord-254419-qw83atrx	30	13	interplay	interplay	NN
cord-254419-qw83atrx	30	14	between	between	IN
cord-254419-qw83atrx	30	15	hypercoagulability	hypercoagulability	NN
cord-254419-qw83atrx	30	16	,	,	,
cord-254419-qw83atrx	30	17	thrombo	thrombo	NN
cord-254419-qw83atrx	30	18	-	-	HYPH
cord-254419-qw83atrx	30	19	inflammation	inflammation	NN
cord-254419-qw83atrx	30	20	,	,	,
cord-254419-qw83atrx	30	21	and	and	CC
cord-254419-qw83atrx	30	22	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	30	23	microvascular	microvascular	JJ
cord-254419-qw83atrx	30	24	thrombosis	thrombosis	NN
cord-254419-qw83atrx	30	25	in	in	IN
cord-254419-qw83atrx	30	26	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	30	27	infection	infection	NN
cord-254419-qw83atrx	30	28	resulting	result	VBG
cord-254419-qw83atrx	30	29	in	in	IN
cord-254419-qw83atrx	30	30	respiratory	respiratory	JJ
cord-254419-qw83atrx	30	31	failure	failure	NN
cord-254419-qw83atrx	30	32	and	and	CC
cord-254419-qw83atrx	30	33	how	how	WRB
cord-254419-qw83atrx	30	34	this	this	DT
cord-254419-qw83atrx	30	35	information	information	NN
cord-254419-qw83atrx	30	36	can	can	MD
cord-254419-qw83atrx	30	37	be	be	VB
cord-254419-qw83atrx	30	38	used	use	VBN
cord-254419-qw83atrx	30	39	to	to	TO
cord-254419-qw83atrx	30	40	design	design	VB
cord-254419-qw83atrx	30	41	clinical	clinical	JJ
cord-254419-qw83atrx	30	42	trials	trial	NNS
cord-254419-qw83atrx	30	43	to	to	TO
cord-254419-qw83atrx	30	44	optimize	optimize	VB
cord-254419-qw83atrx	30	45	patient	patient	JJ
cord-254419-qw83atrx	30	46	outcomes	outcome	NNS
cord-254419-qw83atrx	30	47	.	.	.
cord-254419-qw83atrx	31	1	We	-PRON-	PRP
cord-254419-qw83atrx	31	2	begin	begin	VBP
cord-254419-qw83atrx	31	3	with	with	IN
cord-254419-qw83atrx	31	4	a	a	DT
cord-254419-qw83atrx	31	5	concise	concise	JJ
cord-254419-qw83atrx	31	6	review	review	NN
cord-254419-qw83atrx	31	7	of	of	IN
cord-254419-qw83atrx	31	8	the	the	DT
cord-254419-qw83atrx	31	9	unique	unique	JJ
cord-254419-qw83atrx	31	10	properties	property	NNS
cord-254419-qw83atrx	31	11	of	of	IN
cord-254419-qw83atrx	31	12	SARS	SARS	NNP
cord-254419-qw83atrx	31	13	-	-	:
cord-254419-qw83atrx	31	14	CoV-2	CoV-2	NNP
cord-254419-qw83atrx	31	15	that	that	WDT
cord-254419-qw83atrx	31	16	impacts	impact	VBZ
cord-254419-qw83atrx	31	17	the	the	DT
cord-254419-qw83atrx	31	18	coagulation	coagulation	NN
cord-254419-qw83atrx	31	19	and	and	CC
cord-254419-qw83atrx	31	20	inflammation	inflammation	NN
cord-254419-qw83atrx	31	21	pathways	pathway	NNS
cord-254419-qw83atrx	31	22	before	before	IN
cord-254419-qw83atrx	31	23	proceeding	proceed	VBG
cord-254419-qw83atrx	31	24	with	with	IN
cord-254419-qw83atrx	31	25	an	an	DT
cord-254419-qw83atrx	31	26	in	in	IN
cord-254419-qw83atrx	31	27	-	-	HYPH
cord-254419-qw83atrx	31	28	depth	depth	NN
cord-254419-qw83atrx	31	29	discussion	discussion	NN
cord-254419-qw83atrx	31	30	on	on	IN
cord-254419-qw83atrx	31	31	the	the	DT
cord-254419-qw83atrx	31	32	current	current	JJ
cord-254419-qw83atrx	31	33	available	available	JJ
cord-254419-qw83atrx	31	34	medical	medical	JJ
cord-254419-qw83atrx	31	35	literature	literature	NN
cord-254419-qw83atrx	31	36	.	.	.
cord-254419-qw83atrx	32	1	We	-PRON-	PRP
cord-254419-qw83atrx	32	2	will	will	MD
cord-254419-qw83atrx	32	3	also	also	RB
cord-254419-qw83atrx	32	4	discuss	discuss	VB
cord-254419-qw83atrx	32	5	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	32	6	and	and	CC
cord-254419-qw83atrx	32	7	other	other	JJ
cord-254419-qw83atrx	32	8	pharmacological	pharmacological	JJ
cord-254419-qw83atrx	32	9	strategies	strategy	NNS
cord-254419-qw83atrx	32	10	described	describe	VBN
cord-254419-qw83atrx	32	11	for	for	IN
cord-254419-qw83atrx	32	12	these	these	DT
cord-254419-qw83atrx	32	13	patients	patient	NNS
cord-254419-qw83atrx	32	14	that	that	WDT
cord-254419-qw83atrx	32	15	pertain	pertain	VBP
cord-254419-qw83atrx	32	16	to	to	IN
cord-254419-qw83atrx	32	17	the	the	DT
cord-254419-qw83atrx	32	18	role	role	NN
cord-254419-qw83atrx	32	19	of	of	IN
cord-254419-qw83atrx	32	20	the	the	DT
cord-254419-qw83atrx	32	21	coagulation	coagulation	NN
cord-254419-qw83atrx	32	22	pathway	pathway	NN
cord-254419-qw83atrx	32	23	in	in	IN
cord-254419-qw83atrx	32	24	the	the	DT
cord-254419-qw83atrx	32	25	prevention	prevention	NN
cord-254419-qw83atrx	32	26	and	and	CC
cord-254419-qw83atrx	32	27	management	management	NN
cord-254419-qw83atrx	32	28	of	of	IN
cord-254419-qw83atrx	32	29	COVID-19-induced	COVID-19-induced	NNP
cord-254419-qw83atrx	32	30	respiratory	respiratory	JJ
cord-254419-qw83atrx	32	31	failure	failure	NN
cord-254419-qw83atrx	32	32	.	.	.
cord-254419-qw83atrx	33	1	For	for	IN
cord-254419-qw83atrx	33	2	the	the	DT
cord-254419-qw83atrx	33	3	purpose	purpose	NN
cord-254419-qw83atrx	33	4	of	of	IN
cord-254419-qw83atrx	33	5	this	this	DT
cord-254419-qw83atrx	33	6	review	review	NN
cord-254419-qw83atrx	33	7	,	,	,
cord-254419-qw83atrx	33	8	we	-PRON-	PRP
cord-254419-qw83atrx	33	9	performed	perform	VBD
cord-254419-qw83atrx	33	10	a	a	DT
cord-254419-qw83atrx	33	11	literature	literature	NN
cord-254419-qw83atrx	33	12	search	search	NN
cord-254419-qw83atrx	33	13	on	on	IN
cord-254419-qw83atrx	33	14	PubMed	PubMed	NNP
cord-254419-qw83atrx	33	15	using	use	VBG
cord-254419-qw83atrx	33	16	the	the	DT
cord-254419-qw83atrx	33	17	following	follow	VBG
cord-254419-qw83atrx	33	18	keywords	keyword	NNS
cord-254419-qw83atrx	33	19	:	:	:
cord-254419-qw83atrx	33	20	COVID-19	covid-19	VB
cord-254419-qw83atrx	33	21	,	,	,
cord-254419-qw83atrx	33	22	coronavirus	coronavirus	NN
cord-254419-qw83atrx	33	23	,	,	,
cord-254419-qw83atrx	33	24	SARS	SARS	NNP
cord-254419-qw83atrx	33	25	-	-	HYPH
cord-254419-qw83atrx	33	26	CoV-2	CoV-2	NNP
cord-254419-qw83atrx	33	27	,	,	,
cord-254419-qw83atrx	33	28	thrombosis	thrombosis	NN
cord-254419-qw83atrx	33	29	,	,	,
cord-254419-qw83atrx	33	30	and	and	CC
cord-254419-qw83atrx	33	31	respiratory	respiratory	JJ
cord-254419-qw83atrx	33	32	failure	failure	NN
cord-254419-qw83atrx	33	33	.	.	.
cord-254419-qw83atrx	34	1	This	this	DT
cord-254419-qw83atrx	34	2	review	review	NN
cord-254419-qw83atrx	34	3	is	be	VBZ
cord-254419-qw83atrx	34	4	based	base	VBN
cord-254419-qw83atrx	34	5	on	on	IN
cord-254419-qw83atrx	34	6	previously	previously	RB
cord-254419-qw83atrx	34	7	conducted	conduct	VBN
cord-254419-qw83atrx	34	8	studies	study	NNS
cord-254419-qw83atrx	34	9	and	and	CC
cord-254419-qw83atrx	34	10	does	do	VBZ
cord-254419-qw83atrx	34	11	not	not	RB
cord-254419-qw83atrx	34	12	contain	contain	VB
cord-254419-qw83atrx	34	13	any	any	DT
cord-254419-qw83atrx	34	14	studies	study	NNS
cord-254419-qw83atrx	34	15	with	with	IN
cord-254419-qw83atrx	34	16	human	human	JJ
cord-254419-qw83atrx	34	17	participants	participant	NNS
cord-254419-qw83atrx	34	18	or	or	CC
cord-254419-qw83atrx	34	19	animals	animal	NNS
cord-254419-qw83atrx	34	20	performed	perform	VBN
cord-254419-qw83atrx	34	21	by	by	IN
cord-254419-qw83atrx	34	22	any	any	DT
cord-254419-qw83atrx	34	23	of	of	IN
cord-254419-qw83atrx	34	24	the	the	DT
cord-254419-qw83atrx	34	25	authors	author	NNS
cord-254419-qw83atrx	34	26	.	.	.
cord-254419-qw83atrx	35	1	The	the	DT
cord-254419-qw83atrx	35	2	Virulence	Virulence	NNP
cord-254419-qw83atrx	35	3	of	of	IN
cord-254419-qw83atrx	35	4	SARS	SARS	NNP
cord-254419-qw83atrx	35	5	-	-	HYPH
cord-254419-qw83atrx	35	6	CoV-2	CoV-2	NNP
cord-254419-qw83atrx	35	7	SARS	SARS	NNP
cord-254419-qw83atrx	35	8	-	-	HYPH
cord-254419-qw83atrx	35	9	CoV-2	CoV-2	NNP
cord-254419-qw83atrx	35	10	is	be	VBZ
cord-254419-qw83atrx	35	11	a	a	DT
cord-254419-qw83atrx	35	12	novel	novel	JJ
cord-254419-qw83atrx	35	13	betacoronavirus	betacoronavirus	NN
cord-254419-qw83atrx	35	14	[	[	-LRB-
cord-254419-qw83atrx	35	15	large	large	JJ
cord-254419-qw83atrx	35	16	ribonucleic	ribonucleic	NN
cord-254419-qw83atrx	35	17	acid	acid	NN
cord-254419-qw83atrx	35	18	(	(	-LRB-
cord-254419-qw83atrx	35	19	RNA	RNA	NNP
cord-254419-qw83atrx	35	20	)	)	-RRB-
cord-254419-qw83atrx	35	21	virus	virus	NN
cord-254419-qw83atrx	35	22	]	]	-RRB-
cord-254419-qw83atrx	35	23	that	that	WDT
cord-254419-qw83atrx	35	24	is	be	VBZ
cord-254419-qw83atrx	35	25	similar	similar	JJ
cord-254419-qw83atrx	35	26	to	to	IN
cord-254419-qw83atrx	35	27	the	the	DT
cord-254419-qw83atrx	35	28	earlier	early	JJR
cord-254419-qw83atrx	35	29	SARS	SARS	NNP
cord-254419-qw83atrx	35	30	-	-	HYPH
cord-254419-qw83atrx	35	31	CoV	CoV	NNP
cord-254419-qw83atrx	35	32	virus	virus	NN
cord-254419-qw83atrx	35	33	that	that	WDT
cord-254419-qw83atrx	35	34	caused	cause	VBD
cord-254419-qw83atrx	35	35	the	the	DT
cord-254419-qw83atrx	35	36	severe	severe	JJ
cord-254419-qw83atrx	35	37	acute	acute	JJ
cord-254419-qw83atrx	35	38	respiratory	respiratory	JJ
cord-254419-qw83atrx	35	39	distress	distress	NN
cord-254419-qw83atrx	35	40	(	(	-LRB-
cord-254419-qw83atrx	35	41	SARS	SARS	NNP
cord-254419-qw83atrx	35	42	)	)	-RRB-
cord-254419-qw83atrx	35	43	outbreak	outbreak	NN
cord-254419-qw83atrx	35	44	in	in	IN
cord-254419-qw83atrx	35	45	2003	2003	CD
cord-254419-qw83atrx	35	46	[	[	-LRB-
cord-254419-qw83atrx	35	47	6	6	CD
cord-254419-qw83atrx	35	48	]	]	-RRB-
cord-254419-qw83atrx	35	49	.	.	.
cord-254419-qw83atrx	36	1	Multiple	multiple	JJ
cord-254419-qw83atrx	36	2	spike	spike	NN
cord-254419-qw83atrx	36	3	glycoproteins	glycoprotein	NNS
cord-254419-qw83atrx	36	4	(	(	-LRB-
cord-254419-qw83atrx	36	5	S	s	NN
cord-254419-qw83atrx	36	6	)	)	-RRB-
cord-254419-qw83atrx	36	7	protrude	protrude	VB
cord-254419-qw83atrx	36	8	from	from	IN
cord-254419-qw83atrx	36	9	the	the	DT
cord-254419-qw83atrx	36	10	viral	viral	JJ
cord-254419-qw83atrx	36	11	surface	surface	NN
cord-254419-qw83atrx	36	12	and	and	CC
cord-254419-qw83atrx	36	13	give	give	VB
cord-254419-qw83atrx	36	14	it	-PRON-	PRP
cord-254419-qw83atrx	36	15	a	a	DT
cord-254419-qw83atrx	36	16	halo	halo	NN
cord-254419-qw83atrx	36	17	-	-	HYPH
cord-254419-qw83atrx	36	18	like	like	JJ
cord-254419-qw83atrx	36	19	appearance	appearance	NN
cord-254419-qw83atrx	36	20	(	(	-LRB-
cord-254419-qw83atrx	36	21	hence	hence	RB
cord-254419-qw83atrx	36	22	corona	corona	NNP
cord-254419-qw83atrx	36	23	)	)	-RRB-
cord-254419-qw83atrx	36	24	.	.	.
cord-254419-qw83atrx	37	1	The	the	DT
cord-254419-qw83atrx	37	2	spike	spike	NN
cord-254419-qw83atrx	37	3	S	s	NN
cord-254419-qw83atrx	37	4	protein	protein	NN
cord-254419-qw83atrx	37	5	enables	enable	VBZ
cord-254419-qw83atrx	37	6	the	the	DT
cord-254419-qw83atrx	37	7	virus	virus	NN
cord-254419-qw83atrx	37	8	to	to	TO
cord-254419-qw83atrx	37	9	engage	engage	VB
cord-254419-qw83atrx	37	10	with	with	IN
cord-254419-qw83atrx	37	11	its	-PRON-	PRP$
cord-254419-qw83atrx	37	12	target	target	NN
cord-254419-qw83atrx	37	13	cell	cell	NN
cord-254419-qw83atrx	37	14	receptor	receptor	NN
cord-254419-qw83atrx	37	15	,	,	,
cord-254419-qw83atrx	37	16	angiotensin	angiotensin	NN
cord-254419-qw83atrx	37	17	-	-	HYPH
cord-254419-qw83atrx	37	18	converting	convert	VBG
cord-254419-qw83atrx	37	19	enzyme	enzyme	NN
cord-254419-qw83atrx	37	20	2	2	CD
cord-254419-qw83atrx	37	21	(	(	-LRB-
cord-254419-qw83atrx	37	22	ACE2	ACE2	NNP
cord-254419-qw83atrx	37	23	)	)	-RRB-
cord-254419-qw83atrx	38	1	[	[	-LRB-
cord-254419-qw83atrx	38	2	7	7	CD
cord-254419-qw83atrx	38	3	]	]	-RRB-
cord-254419-qw83atrx	38	4	.	.	.
cord-254419-qw83atrx	39	1	The	the	DT
cord-254419-qw83atrx	39	2	host	host	NN
cord-254419-qw83atrx	39	3	's	's	POS
cord-254419-qw83atrx	39	4	transmembrane	transmembrane	NN
cord-254419-qw83atrx	39	5	protease	protease	NN
cord-254419-qw83atrx	39	6	serine	serine	NN
cord-254419-qw83atrx	39	7	2	2	CD
cord-254419-qw83atrx	39	8	(	(	-LRB-
cord-254419-qw83atrx	39	9	TMPRSS2	TMPRSS2	NNP
cord-254419-qw83atrx	39	10	)	)	-RRB-
cord-254419-qw83atrx	39	11	primes	prime	VBZ
cord-254419-qw83atrx	39	12	the	the	DT
cord-254419-qw83atrx	39	13	spike	spike	NN
cord-254419-qw83atrx	39	14	S	s	NN
cord-254419-qw83atrx	39	15	protein	protein	NN
cord-254419-qw83atrx	39	16	of	of	IN
cord-254419-qw83atrx	39	17	the	the	DT
cord-254419-qw83atrx	39	18	virus	virus	NN
cord-254419-qw83atrx	40	1	to	to	TO
cord-254419-qw83atrx	40	2	facilitate	facilitate	VB
cord-254419-qw83atrx	40	3	its	-PRON-	PRP$
cord-254419-qw83atrx	40	4	internalization	internalization	NN
cord-254419-qw83atrx	40	5	into	into	IN
cord-254419-qw83atrx	40	6	the	the	DT
cord-254419-qw83atrx	40	7	cell	cell	NN
cord-254419-qw83atrx	40	8	[	[	-LRB-
cord-254419-qw83atrx	40	9	8	8	CD
cord-254419-qw83atrx	40	10	]	]	-RRB-
cord-254419-qw83atrx	41	1	(	(	-LRB-
cord-254419-qw83atrx	41	2	Fig	Fig	NNP
cord-254419-qw83atrx	41	3	.	.	NNP
cord-254419-qw83atrx	41	4	1	1	CD
cord-254419-qw83atrx	41	5	)	)	-RRB-
cord-254419-qw83atrx	41	6	.	.	.
cord-254419-qw83atrx	42	1	After	after	IN
cord-254419-qw83atrx	42	2	binding	bind	VBG
cord-254419-qw83atrx	42	3	to	to	IN
cord-254419-qw83atrx	42	4	the	the	DT
cord-254419-qw83atrx	42	5	ACE2	ACE2	NNP
cord-254419-qw83atrx	42	6	receptor	receptor	NN
cord-254419-qw83atrx	42	7	,	,	,
cord-254419-qw83atrx	42	8	the	the	DT
cord-254419-qw83atrx	42	9	virus	virus	NN
cord-254419-qw83atrx	42	10	enters	enter	VBZ
cord-254419-qw83atrx	42	11	the	the	DT
cord-254419-qw83atrx	42	12	cell	cell	NN
cord-254419-qw83atrx	42	13	through	through	IN
cord-254419-qw83atrx	42	14	endocytosis	endocytosis	NN
cord-254419-qw83atrx	42	15	,	,	,
cord-254419-qw83atrx	42	16	releases	release	VBZ
cord-254419-qw83atrx	42	17	ribonucleic	ribonucleic	NN
cord-254419-qw83atrx	42	18	acid	acid	NN
cord-254419-qw83atrx	42	19	(	(	-LRB-
cord-254419-qw83atrx	42	20	RNA	RNA	NNP
cord-254419-qw83atrx	42	21	)	)	-RRB-
cord-254419-qw83atrx	42	22	into	into	IN
cord-254419-qw83atrx	42	23	the	the	DT
cord-254419-qw83atrx	42	24	cytosol	cytosol	NN
cord-254419-qw83atrx	42	25	,	,	,
cord-254419-qw83atrx	42	26	replicates	replicate	VBZ
cord-254419-qw83atrx	42	27	by	by	IN
cord-254419-qw83atrx	42	28	using	use	VBG
cord-254419-qw83atrx	42	29	the	the	DT
cord-254419-qw83atrx	42	30	cell	cell	NN
cord-254419-qw83atrx	42	31	machinery	machinery	NN
cord-254419-qw83atrx	42	32	,	,	,
cord-254419-qw83atrx	42	33	and	and	CC
cord-254419-qw83atrx	42	34	finally	finally	RB
cord-254419-qw83atrx	42	35	,	,	,
cord-254419-qw83atrx	42	36	by	by	IN
cord-254419-qw83atrx	42	37	the	the	DT
cord-254419-qw83atrx	42	38	process	process	NN
cord-254419-qw83atrx	42	39	of	of	IN
cord-254419-qw83atrx	42	40	exocytosis	exocytosis	NN
cord-254419-qw83atrx	42	41	,	,	,
cord-254419-qw83atrx	42	42	is	be	VBZ
cord-254419-qw83atrx	42	43	excreted	excrete	VBN
cord-254419-qw83atrx	42	44	from	from	IN
cord-254419-qw83atrx	42	45	the	the	DT
cord-254419-qw83atrx	42	46	cell	cell	NN
cord-254419-qw83atrx	42	47	[	[	-LRB-
cord-254419-qw83atrx	42	48	9	9	CD
cord-254419-qw83atrx	42	49	]	]	-RRB-
cord-254419-qw83atrx	42	50	.	.	.
cord-254419-qw83atrx	43	1	ACE2	ACE2	NNP
cord-254419-qw83atrx	43	2	is	be	VBZ
cord-254419-qw83atrx	43	3	mostly	mostly	RB
cord-254419-qw83atrx	43	4	expressed	express	VBN
cord-254419-qw83atrx	43	5	in	in	IN
cord-254419-qw83atrx	43	6	the	the	DT
cord-254419-qw83atrx	43	7	airway	airway	NN
cord-254419-qw83atrx	43	8	and	and	CC
cord-254419-qw83atrx	43	9	type	type	NN
cord-254419-qw83atrx	43	10	II	II	NNP
cord-254419-qw83atrx	43	11	pneumocytes	pneumocyte	NNS
cord-254419-qw83atrx	43	12	explaining	explain	VBG
cord-254419-qw83atrx	43	13	the	the	DT
cord-254419-qw83atrx	43	14	tropism	tropism	NN
cord-254419-qw83atrx	43	15	of	of	IN
cord-254419-qw83atrx	43	16	the	the	DT
cord-254419-qw83atrx	43	17	virus	virus	NN
cord-254419-qw83atrx	43	18	to	to	IN
cord-254419-qw83atrx	43	19	the	the	DT
cord-254419-qw83atrx	43	20	respiratory	respiratory	JJ
cord-254419-qw83atrx	43	21	system	system	NN
cord-254419-qw83atrx	43	22	.	.	.
cord-254419-qw83atrx	44	1	Not	not	RB
cord-254419-qw83atrx	44	2	surprisingly	surprisingly	RB
cord-254419-qw83atrx	44	3	,	,	,
cord-254419-qw83atrx	44	4	one	one	CD
cord-254419-qw83atrx	44	5	of	of	IN
cord-254419-qw83atrx	44	6	the	the	DT
cord-254419-qw83atrx	44	7	major	major	JJ
cord-254419-qw83atrx	44	8	features	feature	NNS
cord-254419-qw83atrx	44	9	of	of	IN
cord-254419-qw83atrx	44	10	COVID-19	covid-19	JJ
cord-254419-qw83atrx	44	11	infection	infection	NN
cord-254419-qw83atrx	44	12	is	be	VBZ
cord-254419-qw83atrx	44	13	involvement	involvement	NN
cord-254419-qw83atrx	44	14	of	of	IN
cord-254419-qw83atrx	44	15	the	the	DT
cord-254419-qw83atrx	44	16	respiratory	respiratory	JJ
cord-254419-qw83atrx	44	17	system	system	NN
cord-254419-qw83atrx	44	18	.	.	.
cord-254419-qw83atrx	45	1	Importantly	importantly	RB
cord-254419-qw83atrx	45	2	,	,	,
cord-254419-qw83atrx	45	3	ACE2	ACE2	NNP
cord-254419-qw83atrx	45	4	receptors	receptor	NNS
cord-254419-qw83atrx	45	5	are	be	VBP
cord-254419-qw83atrx	45	6	also	also	RB
cord-254419-qw83atrx	45	7	expressed	express	VBN
cord-254419-qw83atrx	45	8	by	by	IN
cord-254419-qw83atrx	45	9	vascular	vascular	JJ
cord-254419-qw83atrx	45	10	endothelial	endothelial	JJ
cord-254419-qw83atrx	45	11	cells	cell	NNS
cord-254419-qw83atrx	45	12	[	[	-LRB-
cord-254419-qw83atrx	45	13	10	10	CD
cord-254419-qw83atrx	45	14	]	]	-RRB-
cord-254419-qw83atrx	45	15	.	.	.
cord-254419-qw83atrx	46	1	While	while	IN
cord-254419-qw83atrx	46	2	most	most	JJS
cord-254419-qw83atrx	46	3	patients	patient	NNS
cord-254419-qw83atrx	46	4	will	will	MD
cord-254419-qw83atrx	46	5	have	have	VB
cord-254419-qw83atrx	46	6	symptoms	symptom	NNS
cord-254419-qw83atrx	46	7	of	of	IN
cord-254419-qw83atrx	46	8	respiratory	respiratory	JJ
cord-254419-qw83atrx	46	9	tract	tract	NN
cord-254419-qw83atrx	46	10	infection	infection	NN
cord-254419-qw83atrx	46	11	and	and	CC
cord-254419-qw83atrx	46	12	start	start	VB
cord-254419-qw83atrx	46	13	to	to	TO
cord-254419-qw83atrx	46	14	improve	improve	VB
cord-254419-qw83atrx	46	15	within	within	IN
cord-254419-qw83atrx	46	16	a	a	DT
cord-254419-qw83atrx	46	17	week	week	NN
cord-254419-qw83atrx	46	18	,	,	,
cord-254419-qw83atrx	46	19	sudden	sudden	JJ
cord-254419-qw83atrx	46	20	clinical	clinical	JJ
cord-254419-qw83atrx	46	21	deterioration	deterioration	NN
cord-254419-qw83atrx	46	22	7	7	CD
cord-254419-qw83atrx	46	23	-	-	SYM
cord-254419-qw83atrx	46	24	8	8	CD
cord-254419-qw83atrx	46	25	days	day	NNS
cord-254419-qw83atrx	46	26	after	after	IN
cord-254419-qw83atrx	46	27	initial	initial	JJ
cord-254419-qw83atrx	46	28	symptom	symptom	NN
cord-254419-qw83atrx	46	29	onset	onset	NN
cord-254419-qw83atrx	46	30	and	and	CC
cord-254419-qw83atrx	46	31	development	development	NN
cord-254419-qw83atrx	46	32	of	of	IN
cord-254419-qw83atrx	46	33	severe	severe	JJ
cord-254419-qw83atrx	46	34	respiratory	respiratory	JJ
cord-254419-qw83atrx	46	35	failure	failure	NN
cord-254419-qw83atrx	46	36	often	often	RB
cord-254419-qw83atrx	46	37	combined	combine	VBN
cord-254419-qw83atrx	46	38	with	with	IN
cord-254419-qw83atrx	46	39	multiorgan	multiorgan	NNP
cord-254419-qw83atrx	46	40	failure	failure	NN
cord-254419-qw83atrx	46	41	is	be	VBZ
cord-254419-qw83atrx	46	42	commonly	commonly	RB
cord-254419-qw83atrx	46	43	recognized	recognize	VBN
cord-254419-qw83atrx	46	44	[	[	-LRB-
cord-254419-qw83atrx	46	45	11	11	CD
cord-254419-qw83atrx	46	46	]	]	-RRB-
cord-254419-qw83atrx	46	47	.	.	.
cord-254419-qw83atrx	47	1	The	the	DT
cord-254419-qw83atrx	47	2	group	group	NN
cord-254419-qw83atrx	47	3	at	at	IN
cord-254419-qw83atrx	47	4	highest	high	JJS
cord-254419-qw83atrx	47	5	risk	risk	NN
cord-254419-qw83atrx	47	6	of	of	IN
cord-254419-qw83atrx	47	7	deterioration	deterioration	NN
cord-254419-qw83atrx	47	8	includes	include	VBZ
cord-254419-qw83atrx	47	9	the	the	DT
cord-254419-qw83atrx	47	10	elderly	elderly	JJ
cord-254419-qw83atrx	47	11	population	population	NN
cord-254419-qw83atrx	47	12	,	,	,
cord-254419-qw83atrx	47	13	people	people	NNS
cord-254419-qw83atrx	47	14	with	with	IN
cord-254419-qw83atrx	47	15	pre	pre	JJ
cord-254419-qw83atrx	47	16	-	-	JJ
cord-254419-qw83atrx	47	17	existing	existing	JJ
cord-254419-qw83atrx	47	18	chronic	chronic	JJ
cord-254419-qw83atrx	47	19	health	health	NN
cord-254419-qw83atrx	47	20	conditions	condition	NNS
cord-254419-qw83atrx	47	21	(	(	-LRB-
cord-254419-qw83atrx	47	22	e.g.	e.g.	RB
cord-254419-qw83atrx	47	23	,	,	,
cord-254419-qw83atrx	47	24	cancer	cancer	NN
cord-254419-qw83atrx	47	25	,	,	,
cord-254419-qw83atrx	47	26	chronic	chronic	JJ
cord-254419-qw83atrx	47	27	kidney	kidney	NN
cord-254419-qw83atrx	47	28	disease	disease	NN
cord-254419-qw83atrx	47	29	,	,	,
cord-254419-qw83atrx	47	30	chronic	chronic	JJ
cord-254419-qw83atrx	47	31	obstructive	obstructive	JJ
cord-254419-qw83atrx	47	32	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	47	33	disease	disease	NN
cord-254419-qw83atrx	47	34	,	,	,
cord-254419-qw83atrx	47	35	immunocompromised	immunocompromised	JJ
cord-254419-qw83atrx	47	36	state	state	NN
cord-254419-qw83atrx	47	37	,	,	,
cord-254419-qw83atrx	47	38	obesity	obesity	NN
cord-254419-qw83atrx	47	39	,	,	,
cord-254419-qw83atrx	47	40	cardiovascular	cardiovascular	JJ
cord-254419-qw83atrx	47	41	comorbidities	comorbiditie	NNS
cord-254419-qw83atrx	47	42	,	,	,
cord-254419-qw83atrx	47	43	sickle	sickle	NN
cord-254419-qw83atrx	47	44	cell	cell	NN
cord-254419-qw83atrx	47	45	disease	disease	NN
cord-254419-qw83atrx	47	46	and	and	CC
cord-254419-qw83atrx	47	47	type	type	NN
cord-254419-qw83atrx	47	48	2	2	CD
cord-254419-qw83atrx	47	49	diabetes	diabetes	NN
cord-254419-qw83atrx	47	50	mellitus	mellitus	NN
cord-254419-qw83atrx	47	51	)	)	-RRB-
cord-254419-qw83atrx	47	52	[	[	-LRB-
cord-254419-qw83atrx	47	53	12	12	CD
cord-254419-qw83atrx	47	54	]	]	-RRB-
cord-254419-qw83atrx	47	55	.	.	.
cord-254419-qw83atrx	48	1	In	in	IN
cord-254419-qw83atrx	48	2	addition	addition	NN
cord-254419-qw83atrx	48	3	,	,	,
cord-254419-qw83atrx	48	4	patients	patient	NNS
cord-254419-qw83atrx	48	5	from	from	IN
cord-254419-qw83atrx	48	6	certain	certain	JJ
cord-254419-qw83atrx	48	7	ethnicity	ethnicity	NN
cord-254419-qw83atrx	48	8	groups	group	NNS
cord-254419-qw83atrx	48	9	(	(	-LRB-
cord-254419-qw83atrx	48	10	e.g.	e.g.	RB
cord-254419-qw83atrx	48	11	,	,	,
cord-254419-qw83atrx	48	12	Afro	Afro	NNP
cord-254419-qw83atrx	48	13	-	-	HYPH
cord-254419-qw83atrx	48	14	Americans	Americans	NNPS
cord-254419-qw83atrx	48	15	,	,	,
cord-254419-qw83atrx	48	16	South	South	NNPS
cord-254419-qw83atrx	48	17	Asians	Asians	NNPS
cord-254419-qw83atrx	48	18	,	,	,
cord-254419-qw83atrx	48	19	and	and	CC
cord-254419-qw83atrx	48	20	minority	minority	NN
cord-254419-qw83atrx	48	21	ethnic	ethnic	JJ
cord-254419-qw83atrx	48	22	groups	group	NNS
cord-254419-qw83atrx	48	23	)	)	-RRB-
cord-254419-qw83atrx	48	24	and	and	CC
cord-254419-qw83atrx	48	25	blood	blood	NN
cord-254419-qw83atrx	48	26	groups	group	NNS
cord-254419-qw83atrx	48	27	(	(	-LRB-
cord-254419-qw83atrx	48	28	e.g.	e.g.	RB
cord-254419-qw83atrx	48	29	,	,	,
cord-254419-qw83atrx	48	30	blood	blood	NN
cord-254419-qw83atrx	48	31	group	group	NN
cord-254419-qw83atrx	48	32	A	a	NN
cord-254419-qw83atrx	48	33	with	with	IN
cord-254419-qw83atrx	48	34	3p21.31	3p21.31	JJ
cord-254419-qw83atrx	48	35	gene	gene	NN
cord-254419-qw83atrx	48	36	cluster	cluster	NN
cord-254419-qw83atrx	48	37	)	)	-RRB-
cord-254419-qw83atrx	48	38	have	have	VBP
cord-254419-qw83atrx	48	39	been	be	VBN
cord-254419-qw83atrx	48	40	Fig	Fig	NNP
cord-254419-qw83atrx	48	41	.	.	.
cord-254419-qw83atrx	49	1	1	1	LS
cord-254419-qw83atrx	50	1	Indirect	indirect	JJ
cord-254419-qw83atrx	50	2	and	and	CC
cord-254419-qw83atrx	50	3	direct	direct	JJ
cord-254419-qw83atrx	50	4	injury	injury	NN
cord-254419-qw83atrx	50	5	to	to	IN
cord-254419-qw83atrx	50	6	the	the	DT
cord-254419-qw83atrx	50	7	lungs	lung	NNS
cord-254419-qw83atrx	50	8	by	by	IN
cord-254419-qw83atrx	50	9	the	the	DT
cord-254419-qw83atrx	50	10	severe	severe	JJ
cord-254419-qw83atrx	50	11	acute	acute	JJ
cord-254419-qw83atrx	50	12	respiratory	respiratory	JJ
cord-254419-qw83atrx	50	13	syndrome	syndrome	NN
cord-254419-qw83atrx	50	14	coronavirus	coronavirus	NN
cord-254419-qw83atrx	50	15	2	2	CD
cord-254419-qw83atrx	50	16	involving	involve	VBG
cord-254419-qw83atrx	50	17	the	the	DT
cord-254419-qw83atrx	50	18	interplay	interplay	NN
cord-254419-qw83atrx	50	19	between	between	IN
cord-254419-qw83atrx	50	20	coagulation	coagulation	NN
cord-254419-qw83atrx	50	21	and	and	CC
cord-254419-qw83atrx	50	22	inflammation	inflammation	NN
cord-254419-qw83atrx	50	23	pathways	pathway	NNS
cord-254419-qw83atrx	50	24	.	.	.
cord-254419-qw83atrx	51	1	ACE2	ACE2	NNP
cord-254419-qw83atrx	51	2	angiotensin	angiotensin	NN
cord-254419-qw83atrx	51	3	-	-	HYPH
cord-254419-qw83atrx	51	4	converting	convert	VBG
cord-254419-qw83atrx	51	5	enzyme	enzyme	NN
cord-254419-qw83atrx	51	6	2	2	CD
cord-254419-qw83atrx	51	7	,	,	,
cord-254419-qw83atrx	51	8	CRP	CRP	NNP
cord-254419-qw83atrx	51	9	C	C	NNP
cord-254419-qw83atrx	51	10	-	-	HYPH
cord-254419-qw83atrx	51	11	reactive	reactive	JJ
cord-254419-qw83atrx	51	12	protein	protein	NN
cord-254419-qw83atrx	51	13	,	,	,
cord-254419-qw83atrx	51	14	ESR	ESR	NNP
cord-254419-qw83atrx	51	15	erythrocyte	erythrocyte	NN
cord-254419-qw83atrx	51	16	sedimentation	sedimentation	NN
cord-254419-qw83atrx	51	17	rate	rate	NN
cord-254419-qw83atrx	51	18	,	,	,
cord-254419-qw83atrx	51	19	LDH	LDH	NNP
cord-254419-qw83atrx	51	20	lactate	lactate	NN
cord-254419-qw83atrx	51	21	dehydrogenase	dehydrogenase	NN
cord-254419-qw83atrx	51	22	,	,	,
cord-254419-qw83atrx	51	23	NETS	NETS	NNP
cord-254419-qw83atrx	51	24	neutrophil	neutrophil	NN
cord-254419-qw83atrx	51	25	extracellular	extracellular	JJ
cord-254419-qw83atrx	51	26	traps	trap	NNS
cord-254419-qw83atrx	51	27	,	,	,
cord-254419-qw83atrx	51	28	SARS	SARS	NNP
cord-254419-qw83atrx	51	29	-	-	HYPH
cord-254419-qw83atrx	51	30	COV-2	COV-2	NNP
cord-254419-qw83atrx	51	31	severe	severe	JJ
cord-254419-qw83atrx	51	32	acute	acute	JJ
cord-254419-qw83atrx	51	33	respiratory	respiratory	JJ
cord-254419-qw83atrx	51	34	syndrome	syndrome	NN
cord-254419-qw83atrx	51	35	coronavirus	coronavirus	NN
cord-254419-qw83atrx	51	36	2	2	CD
cord-254419-qw83atrx	52	1	,	,	,
cord-254419-qw83atrx	52	2	TMPRSS2	TMPRSS2	NNP
cord-254419-qw83atrx	52	3	transmembrane	transmembrane	NN
cord-254419-qw83atrx	52	4	protease	protease	NN
cord-254419-qw83atrx	52	5	serine	serine	NN
cord-254419-qw83atrx	52	6	2	2	CD
cord-254419-qw83atrx	52	7	shown	show	VBN
cord-254419-qw83atrx	52	8	to	to	TO
cord-254419-qw83atrx	52	9	be	be	VB
cord-254419-qw83atrx	52	10	at	at	IN
cord-254419-qw83atrx	52	11	higher	high	JJR
cord-254419-qw83atrx	52	12	risk	risk	NN
cord-254419-qw83atrx	52	13	of	of	IN
cord-254419-qw83atrx	52	14	worse	bad	JJR
cord-254419-qw83atrx	52	15	outcomes	outcome	NNS
cord-254419-qw83atrx	52	16	[	[	-LRB-
cord-254419-qw83atrx	52	17	13	13	CD
cord-254419-qw83atrx	52	18	]	]	-RRB-
cord-254419-qw83atrx	53	1	[	[	-LRB-
cord-254419-qw83atrx	53	2	14	14	CD
cord-254419-qw83atrx	53	3	]	]	-RRB-
cord-254419-qw83atrx	54	1	[	[	-LRB-
cord-254419-qw83atrx	54	2	15	15	CD
cord-254419-qw83atrx	54	3	]	]	-RRB-
cord-254419-qw83atrx	55	1	(	(	-LRB-
cord-254419-qw83atrx	55	2	Fig	Fig	NNP
cord-254419-qw83atrx	55	3	.	.	NNP
cord-254419-qw83atrx	55	4	2	2	CD
cord-254419-qw83atrx	55	5	)	)	-RRB-
cord-254419-qw83atrx	55	6	.	.	.
cord-254419-qw83atrx	56	1	Current	current	JJ
cord-254419-qw83atrx	56	2	literature	literature	NN
cord-254419-qw83atrx	56	3	suggests	suggest	VBZ
cord-254419-qw83atrx	56	4	that	that	IN
cord-254419-qw83atrx	56	5	a	a	DT
cord-254419-qw83atrx	56	6	unique	unique	JJ
cord-254419-qw83atrx	56	7	pattern	pattern	NN
cord-254419-qw83atrx	56	8	of	of	IN
cord-254419-qw83atrx	56	9	immune	immune	JJ
cord-254419-qw83atrx	56	10	dysfunction	dysfunction	NN
cord-254419-qw83atrx	56	11	is	be	VBZ
cord-254419-qw83atrx	56	12	responsible	responsible	JJ
cord-254419-qw83atrx	56	13	for	for	IN
cord-254419-qw83atrx	56	14	this	this	DT
cord-254419-qw83atrx	56	15	disease	disease	NN
cord-254419-qw83atrx	56	16	progression	progression	NN
cord-254419-qw83atrx	56	17	in	in	IN
cord-254419-qw83atrx	56	18	high	high	JJ
cord-254419-qw83atrx	56	19	-	-	HYPH
cord-254419-qw83atrx	56	20	risk	risk	NN
cord-254419-qw83atrx	56	21	patients	patient	NNS
cord-254419-qw83atrx	56	22	.	.	.
cord-254419-qw83atrx	57	1	Suppression	suppression	NN
cord-254419-qw83atrx	57	2	of	of	IN
cord-254419-qw83atrx	57	3	lymphocytes	lymphocyte	NNS
cord-254419-qw83atrx	57	4	by	by	IN
cord-254419-qw83atrx	57	5	the	the	DT
cord-254419-qw83atrx	57	6	virus	virus	NN
cord-254419-qw83atrx	57	7	leads	lead	VBZ
cord-254419-qw83atrx	57	8	to	to	IN
cord-254419-qw83atrx	57	9	a	a	DT
cord-254419-qw83atrx	57	10	complicated	complicated	JJ
cord-254419-qw83atrx	57	11	immune	immune	JJ
cord-254419-qw83atrx	57	12	mechanism	mechanism	NN
cord-254419-qw83atrx	57	13	with	with	IN
cord-254419-qw83atrx	57	14	activated	activate	VBN
cord-254419-qw83atrx	57	15	macrophages	macrophage	NNS
cord-254419-qw83atrx	57	16	which	which	WDT
cord-254419-qw83atrx	57	17	releases	release	VBZ
cord-254419-qw83atrx	57	18	cytokines	cytokine	NNS
cord-254419-qw83atrx	57	19	(	(	-LRB-
cord-254419-qw83atrx	57	20	Fig	Fig	NNP
cord-254419-qw83atrx	57	21	.	.	.
cord-254419-qw83atrx	57	22	1	1	CD
cord-254419-qw83atrx	57	23	)	)	-RRB-
cord-254419-qw83atrx	57	24	.	.	.
cord-254419-qw83atrx	58	1	This	this	DT
cord-254419-qw83atrx	58	2	creates	create	VBZ
cord-254419-qw83atrx	58	3	a	a	DT
cord-254419-qw83atrx	58	4	cytokine	cytokine	NN
cord-254419-qw83atrx	58	5	storm	storm	NN
cord-254419-qw83atrx	58	6	[	[	-LRB-
cord-254419-qw83atrx	58	7	mostly	mostly	RB
cord-254419-qw83atrx	58	8	interleukin	interleukin	JJ
cord-254419-qw83atrx	58	9	IL-1b	IL-1b	NNS
cord-254419-qw83atrx	58	10	and	and	CC
cord-254419-qw83atrx	58	11	IL-6	IL-6	NNP
cord-254419-qw83atrx	58	12	]	]	-RRB-
cord-254419-qw83atrx	58	13	,	,	,
cord-254419-qw83atrx	58	14	promoting	promote	VBG
cord-254419-qw83atrx	58	15	expression	expression	NN
cord-254419-qw83atrx	58	16	of	of	IN
cord-254419-qw83atrx	58	17	adhesion	adhesion	NN
cord-254419-qw83atrx	58	18	molecules	molecule	NNS
cord-254419-qw83atrx	58	19	for	for	IN
cord-254419-qw83atrx	58	20	endothelial	endothelial	JJ
cord-254419-qw83atrx	58	21	activation	activation	NN
cord-254419-qw83atrx	58	22	,	,	,
cord-254419-qw83atrx	58	23	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	58	24	cell	cell	NN
cord-254419-qw83atrx	58	25	infiltration	infiltration	NN
cord-254419-qw83atrx	58	26	,	,	,
cord-254419-qw83atrx	58	27	and	and	CC
cord-254419-qw83atrx	58	28	vascular	vascular	JJ
cord-254419-qw83atrx	58	29	inflammation	inflammation	NN
cord-254419-qw83atrx	58	30	.	.	.
cord-254419-qw83atrx	59	1	Endothelial	endothelial	NN
cord-254419-qw83atrx	59	2	cells	cell	NNS
cord-254419-qw83atrx	59	3	release	release	VBP
cord-254419-qw83atrx	59	4	pro	pro	JJ
cord-254419-qw83atrx	59	5	-	-	JJ
cord-254419-qw83atrx	59	6	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	59	7	cytokines	cytokine	NNS
cord-254419-qw83atrx	59	8	that	that	WDT
cord-254419-qw83atrx	59	9	contribute	contribute	VBP
cord-254419-qw83atrx	59	10	to	to	IN
cord-254419-qw83atrx	59	11	propagation	propagation	NN
cord-254419-qw83atrx	59	12	of	of	IN
cord-254419-qw83atrx	59	13	microcirculatory	microcirculatory	JJ
cord-254419-qw83atrx	59	14	lesions	lesion	NNS
cord-254419-qw83atrx	59	15	.	.	.
cord-254419-qw83atrx	60	1	The	the	DT
cord-254419-qw83atrx	60	2	dysfunctional	dysfunctional	JJ
cord-254419-qw83atrx	60	3	endothelium	endothelium	NN
cord-254419-qw83atrx	60	4	then	then	RB
cord-254419-qw83atrx	60	5	becomes	become	VBZ
cord-254419-qw83atrx	60	6	proadhesive	proadhesive	JJ
cord-254419-qw83atrx	60	7	and	and	CC
cord-254419-qw83atrx	60	8	pro	pro	JJ
cord-254419-qw83atrx	60	9	-	-	JJ
cord-254419-qw83atrx	60	10	coagulant	coagulant	JJ
cord-254419-qw83atrx	60	11	[	[	-LRB-
cord-254419-qw83atrx	60	12	16	16	CD
cord-254419-qw83atrx	60	13	]	]	-RRB-
cord-254419-qw83atrx	60	14	.	.	.
cord-254419-qw83atrx	61	1	Presence	presence	NN
cord-254419-qw83atrx	61	2	of	of	IN
cord-254419-qw83atrx	61	3	viral	viral	JJ
cord-254419-qw83atrx	61	4	elements	element	NNS
cord-254419-qw83atrx	61	5	within	within	IN
cord-254419-qw83atrx	61	6	endothelial	endothelial	JJ
cord-254419-qw83atrx	61	7	cells	cell	NNS
cord-254419-qw83atrx	61	8	causes	cause	VBZ
cord-254419-qw83atrx	61	9	endotheliitis	endotheliitis	NN
cord-254419-qw83atrx	61	10	and	and	CC
cord-254419-qw83atrx	61	11	accumulation	accumulation	NN
cord-254419-qw83atrx	61	12	of	of	IN
cord-254419-qw83atrx	61	13	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	61	14	cells	cell	NNS
cord-254419-qw83atrx	61	15	with	with	IN
cord-254419-qw83atrx	61	16	increasing	increase	VBG
cord-254419-qw83atrx	61	17	cell	cell	NN
cord-254419-qw83atrx	61	18	death	death	NN
cord-254419-qw83atrx	61	19	,	,	,
cord-254419-qw83atrx	61	20	leading	lead	VBG
cord-254419-qw83atrx	61	21	to	to	IN
cord-254419-qw83atrx	61	22	impairment	impairment	NN
cord-254419-qw83atrx	61	23	of	of	IN
cord-254419-qw83atrx	61	24	microcirculatory	microcirculatory	JJ
cord-254419-qw83atrx	61	25	function	function	NN
cord-254419-qw83atrx	61	26	in	in	IN
cord-254419-qw83atrx	61	27	different	different	JJ
cord-254419-qw83atrx	61	28	vascular	vascular	JJ
cord-254419-qw83atrx	61	29	beds	bed	NNS
cord-254419-qw83atrx	61	30	and	and	CC
cord-254419-qw83atrx	61	31	their	-PRON-	PRP$
cord-254419-qw83atrx	61	32	consequent	consequent	JJ
cord-254419-qw83atrx	61	33	clinical	clinical	JJ
cord-254419-qw83atrx	61	34	effects	effect	NNS
cord-254419-qw83atrx	61	35	[	[	-LRB-
cord-254419-qw83atrx	61	36	17	17	CD
cord-254419-qw83atrx	61	37	]	]	-RRB-
cord-254419-qw83atrx	61	38	.	.	.
cord-254419-qw83atrx	62	1	A	a	DT
cord-254419-qw83atrx	62	2	study	study	NN
cord-254419-qw83atrx	62	3	that	that	WDT
cord-254419-qw83atrx	62	4	examined	examine	VBD
cord-254419-qw83atrx	62	5	the	the	DT
cord-254419-qw83atrx	62	6	serum	serum	NN
cord-254419-qw83atrx	62	7	of	of	IN
cord-254419-qw83atrx	62	8	50	50	CD
cord-254419-qw83atrx	62	9	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	62	10	patients	patient	NNS
cord-254419-qw83atrx	62	11	found	find	VBD
cord-254419-qw83atrx	62	12	elevated	elevated	JJ
cord-254419-qw83atrx	62	13	markers	marker	NNS
cord-254419-qw83atrx	62	14	of	of	IN
cord-254419-qw83atrx	62	15	neutrophil	neutrophil	NN
cord-254419-qw83atrx	62	16	extracellular	extracellular	JJ
cord-254419-qw83atrx	62	17	traps	trap	NNS
cord-254419-qw83atrx	62	18	(	(	-LRB-
cord-254419-qw83atrx	62	19	NETs	nets	NN
cord-254419-qw83atrx	62	20	)	)	-RRB-
cord-254419-qw83atrx	62	21	[	[	-LRB-
cord-254419-qw83atrx	62	22	18	18	CD
cord-254419-qw83atrx	62	23	]	]	-RRB-
cord-254419-qw83atrx	62	24	.	.	.
cord-254419-qw83atrx	63	1	NETs	net	NNS
cord-254419-qw83atrx	63	2	are	be	VBP
cord-254419-qw83atrx	63	3	microbicidal	microbicidal	NN
cord-254419-qw83atrx	63	4	proteins	protein	NNS
cord-254419-qw83atrx	63	5	,	,	,
cord-254419-qw83atrx	63	6	extracellular	extracellular	JJ
cord-254419-qw83atrx	63	7	webs	web	NNS
cord-254419-qw83atrx	63	8	of	of	IN
cord-254419-qw83atrx	63	9	chromatin	chromatin	NN
cord-254419-qw83atrx	63	10	,	,	,
cord-254419-qw83atrx	63	11	and	and	CC
cord-254419-qw83atrx	63	12	oxidant	oxidant	JJ
cord-254419-qw83atrx	63	13	enzymes	enzyme	NNS
cord-254419-qw83atrx	63	14	that	that	WDT
cord-254419-qw83atrx	63	15	are	be	VBP
cord-254419-qw83atrx	63	16	released	release	VBN
cord-254419-qw83atrx	63	17	by	by	IN
cord-254419-qw83atrx	63	18	neutrophils	neutrophil	NNS
cord-254419-qw83atrx	63	19	to	to	TO
cord-254419-qw83atrx	63	20	contain	contain	VB
cord-254419-qw83atrx	63	21	infections	infection	NNS
cord-254419-qw83atrx	63	22	.	.	.
cord-254419-qw83atrx	64	1	NETs	net	NNS
cord-254419-qw83atrx	64	2	have	have	VBP
cord-254419-qw83atrx	64	3	potential	potential	NN
cord-254419-qw83atrx	64	4	to	to	TO
cord-254419-qw83atrx	64	5	cause	cause	VB
cord-254419-qw83atrx	64	6	inflammation	inflammation	NN
cord-254419-qw83atrx	64	7	and	and	CC
cord-254419-qw83atrx	64	8	microvascular	microvascular	JJ
cord-254419-qw83atrx	64	9	thrombosis	thrombosis	NN
cord-254419-qw83atrx	64	10	in	in	IN
cord-254419-qw83atrx	64	11	the	the	DT
cord-254419-qw83atrx	64	12	lungs	lung	NNS
cord-254419-qw83atrx	64	13	,	,	,
cord-254419-qw83atrx	64	14	causing	cause	VBG
cord-254419-qw83atrx	64	15	respiratory	respiratory	JJ
cord-254419-qw83atrx	64	16	failure	failure	NN
cord-254419-qw83atrx	64	17	.	.	.
cord-254419-qw83atrx	65	1	Highly	highly	RB
cord-254419-qw83atrx	65	2	specific	specific	JJ
cord-254419-qw83atrx	65	3	markers	marker	NNS
cord-254419-qw83atrx	65	4	of	of	IN
cord-254419-qw83atrx	65	5	NETs	net	NNS
cord-254419-qw83atrx	65	6	such	such	JJ
cord-254419-qw83atrx	65	7	as	as	IN
cord-254419-qw83atrx	65	8	myeloperoxidase	myeloperoxidase	NNP
cord-254419-qw83atrx	65	9	(	(	-LRB-
cord-254419-qw83atrx	65	10	MPO)-deoxyribonucleic	MPO)-deoxyribonucleic	NNP
cord-254419-qw83atrx	65	11	acid	acid	NN
cord-254419-qw83atrx	65	12	(	(	-LRB-
cord-254419-qw83atrx	65	13	DNA	DNA	NNP
cord-254419-qw83atrx	65	14	)	)	-RRB-
cord-254419-qw83atrx	65	15	,	,	,
cord-254419-qw83atrx	65	16	and	and	CC
cord-254419-qw83atrx	65	17	citrullinated	citrullinate	VBD
cord-254419-qw83atrx	65	18	histone	histone	NN
cord-254419-qw83atrx	65	19	H3	H3	NNP
cord-254419-qw83atrx	65	20	(	(	-LRB-
cord-254419-qw83atrx	65	21	Cit	Cit	NNP
cord-254419-qw83atrx	65	22	-	-	HYPH
cord-254419-qw83atrx	65	23	H3	H3	NNP
cord-254419-qw83atrx	65	24	)	)	-RRB-
cord-254419-qw83atrx	65	25	were	be	VBD
cord-254419-qw83atrx	65	26	found	find	VBN
cord-254419-qw83atrx	65	27	to	to	TO
cord-254419-qw83atrx	65	28	be	be	VB
cord-254419-qw83atrx	65	29	elevated	elevate	VBN
cord-254419-qw83atrx	65	30	in	in	IN
cord-254419-qw83atrx	65	31	this	this	DT
cord-254419-qw83atrx	65	32	study	study	NN
cord-254419-qw83atrx	65	33	.	.	.
cord-254419-qw83atrx	66	1	These	these	DT
cord-254419-qw83atrx	66	2	collective	collective	JJ
cord-254419-qw83atrx	66	3	findings	finding	NNS
cord-254419-qw83atrx	66	4	suggest	suggest	VBP
cord-254419-qw83atrx	66	5	a	a	DT
cord-254419-qw83atrx	66	6	unique	unique	JJ
cord-254419-qw83atrx	66	7	ability	ability	NN
cord-254419-qw83atrx	66	8	of	of	IN
cord-254419-qw83atrx	66	9	the	the	DT
cord-254419-qw83atrx	66	10	virus	virus	NN
cord-254419-qw83atrx	66	11	to	to	TO
cord-254419-qw83atrx	66	12	cause	cause	VB
cord-254419-qw83atrx	66	13	intense	intense	JJ
cord-254419-qw83atrx	66	14	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	66	15	reaction	reaction	NN
cord-254419-qw83atrx	66	16	that	that	WDT
cord-254419-qw83atrx	66	17	makes	make	VBZ
cord-254419-qw83atrx	66	18	the	the	DT
cord-254419-qw83atrx	66	19	virus	virus	NN
cord-254419-qw83atrx	66	20	lethal	lethal	JJ
cord-254419-qw83atrx	66	21	.	.	.
cord-254419-qw83atrx	67	1	Severe	severe	JJ
cord-254419-qw83atrx	67	2	hypercoagulability	hypercoagulability	NN
cord-254419-qw83atrx	67	3	with	with	IN
cord-254419-qw83atrx	67	4	respiratory	respiratory	JJ
cord-254419-qw83atrx	67	5	failure	failure	NN
cord-254419-qw83atrx	67	6	is	be	VBZ
cord-254419-qw83atrx	67	7	a	a	DT
cord-254419-qw83atrx	67	8	recognized	recognize	VBN
cord-254419-qw83atrx	67	9	feature	feature	NN
cord-254419-qw83atrx	67	10	of	of	IN
cord-254419-qw83atrx	67	11	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	67	12	patients	patient	NNS
cord-254419-qw83atrx	67	13	admitted	admit	VBN
cord-254419-qw83atrx	67	14	in	in	IN
cord-254419-qw83atrx	67	15	intensive	intensive	JJ
cord-254419-qw83atrx	67	16	care	care	NN
cord-254419-qw83atrx	67	17	units	unit	NNS
cord-254419-qw83atrx	67	18	(	(	-LRB-
cord-254419-qw83atrx	67	19	ICU	ICU	NNP
cord-254419-qw83atrx	67	20	)	)	-RRB-
cord-254419-qw83atrx	67	21	[	[	-LRB-
cord-254419-qw83atrx	67	22	19	19	CD
cord-254419-qw83atrx	67	23	]	]	-RRB-
cord-254419-qw83atrx	67	24	.	.	.
cord-254419-qw83atrx	68	1	A	a	DT
cord-254419-qw83atrx	68	2	combination	combination	NN
cord-254419-qw83atrx	68	3	of	of	IN
cord-254419-qw83atrx	68	4	profound	profound	JJ
cord-254419-qw83atrx	68	5	inflammation	inflammation	NN
cord-254419-qw83atrx	68	6	Fig	fig	NN
cord-254419-qw83atrx	68	7	.	.	NNP
cord-254419-qw83atrx	68	8	2	2	CD
cord-254419-qw83atrx	68	9	Currently	currently	RB
cord-254419-qw83atrx	68	10	known	know	VBN
cord-254419-qw83atrx	68	11	clinical	clinical	JJ
cord-254419-qw83atrx	68	12	and	and	CC
cord-254419-qw83atrx	68	13	laboratory	laboratory	NN
cord-254419-qw83atrx	68	14	biomarkers	biomarker	NNS
cord-254419-qw83atrx	68	15	of	of	IN
cord-254419-qw83atrx	68	16	severity	severity	NN
cord-254419-qw83atrx	68	17	to	to	TO
cord-254419-qw83atrx	68	18	predict	predict	VB
cord-254419-qw83atrx	68	19	disease	disease	NN
cord-254419-qw83atrx	68	20	progression	progression	NN
cord-254419-qw83atrx	68	21	,	,	,
cord-254419-qw83atrx	68	22	combining	combine	VBG
cord-254419-qw83atrx	68	23	with	with	IN
cord-254419-qw83atrx	68	24	timely	timely	RB
cord-254419-qw83atrx	68	25	antiviral	antiviral	JJ
cord-254419-qw83atrx	68	26	,	,	,
cord-254419-qw83atrx	68	27	anti	anti	JJ
cord-254419-qw83atrx	68	28	-	-	JJ
cord-254419-qw83atrx	68	29	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	68	30	,	,	,
cord-254419-qw83atrx	68	31	and	and	CC
cord-254419-qw83atrx	68	32	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	68	33	intervention	intervention	NN
cord-254419-qw83atrx	68	34	to	to	TO
cord-254419-qw83atrx	68	35	optimize	optimize	VB
cord-254419-qw83atrx	68	36	outcome	outcome	NN
cord-254419-qw83atrx	68	37	.	.	.
cord-254419-qw83atrx	69	1	CHD	CHD	NNP
cord-254419-qw83atrx	69	2	chronic	chronic	JJ
cord-254419-qw83atrx	69	3	heart	heart	NN
cord-254419-qw83atrx	69	4	disease	disease	NN
cord-254419-qw83atrx	69	5	,	,	,
cord-254419-qw83atrx	69	6	CLD	CLD	NNP
cord-254419-qw83atrx	69	7	chronic	chronic	JJ
cord-254419-qw83atrx	69	8	lung	lung	NN
cord-254419-qw83atrx	69	9	disease	disease	NN
cord-254419-qw83atrx	69	10	,	,	,
cord-254419-qw83atrx	69	11	CKD	CKD	NNP
cord-254419-qw83atrx	69	12	chronic	chronic	JJ
cord-254419-qw83atrx	69	13	kidney	kidney	NN
cord-254419-qw83atrx	69	14	disease	disease	NN
cord-254419-qw83atrx	69	15	,	,	,
cord-254419-qw83atrx	69	16	DOACS	DOACS	NNP
cord-254419-qw83atrx	69	17	direct	direct	JJ
cord-254419-qw83atrx	69	18	oral	oral	JJ
cord-254419-qw83atrx	69	19	anticoagulants	anticoagulant	NNS
cord-254419-qw83atrx	69	20	,	,	,
cord-254419-qw83atrx	69	21	FDPs	fdp	NNS
cord-254419-qw83atrx	69	22	fibrinogen	fibrinogen	NN
cord-254419-qw83atrx	69	23	degradation	degradation	NN
cord-254419-qw83atrx	69	24	products	product	NNS
cord-254419-qw83atrx	69	25	,	,	,
cord-254419-qw83atrx	69	26	HTN	HTN	NNP
cord-254419-qw83atrx	69	27	hypertension	hypertension	NN
cord-254419-qw83atrx	69	28	,	,	,
cord-254419-qw83atrx	69	29	IFN	IFN	NNP
cord-254419-qw83atrx	69	30	interferon	interferon	NN
cord-254419-qw83atrx	69	31	,	,	,
cord-254419-qw83atrx	69	32	JAK	JAK	NNP
cord-254419-qw83atrx	69	33	Janus	Janus	NNP
cord-254419-qw83atrx	69	34	kinase	kinase	VBZ
cord-254419-qw83atrx	69	35	,	,	,
cord-254419-qw83atrx	69	36	LDH	LDH	NNP
cord-254419-qw83atrx	69	37	lactate	lactate	NN
cord-254419-qw83atrx	69	38	dehydrogenase	dehydrogenase	NN
cord-254419-qw83atrx	69	39	,	,	,
cord-254419-qw83atrx	69	40	LMWH	LMWH	NNP
cord-254419-qw83atrx	69	41	low	low	JJ
cord-254419-qw83atrx	69	42	molecular	molecular	JJ
cord-254419-qw83atrx	69	43	weight	weight	NN
cord-254419-qw83atrx	69	44	heparin	heparin	NN
cord-254419-qw83atrx	69	45	,	,	,
cord-254419-qw83atrx	69	46	NSAIDS	NSAIDS	NNP
cord-254419-qw83atrx	69	47	nonsteroidal	nonsteroidal	JJ
cord-254419-qw83atrx	69	48	anti	anti	JJ
cord-254419-qw83atrx	69	49	-	-	JJ
cord-254419-qw83atrx	69	50	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	69	51	drugs	drug	NNS
cord-254419-qw83atrx	69	52	,	,	,
cord-254419-qw83atrx	69	53	PT	PT	NNP
cord-254419-qw83atrx	69	54	prothrombin	prothrombin	NN
cord-254419-qw83atrx	69	55	time	time	NN
cord-254419-qw83atrx	69	56	,	,	,
cord-254419-qw83atrx	69	57	TNF	TNF	NNP
cord-254419-qw83atrx	69	58	tumor	tumor	NN
cord-254419-qw83atrx	69	59	necrosis	necrosis	NN
cord-254419-qw83atrx	69	60	factor	factor	NN
cord-254419-qw83atrx	69	61	,	,	,
cord-254419-qw83atrx	69	62	VW	VW	NNP
cord-254419-qw83atrx	69	63	Ag	Ag	NNP
cord-254419-qw83atrx	69	64	Von	Von	NNP
cord-254419-qw83atrx	69	65	Willebrand	Willebrand	NNP
cord-254419-qw83atrx	69	66	antigen	antigen	NN
cord-254419-qw83atrx	69	67	and	and	CC
cord-254419-qw83atrx	69	68	microvascular	microvascular	JJ
cord-254419-qw83atrx	69	69	thrombosis	thrombosis	NN
cord-254419-qw83atrx	69	70	appears	appear	VBZ
cord-254419-qw83atrx	69	71	to	to	TO
cord-254419-qw83atrx	69	72	be	be	VB
cord-254419-qw83atrx	69	73	responsible	responsible	JJ
cord-254419-qw83atrx	69	74	for	for	IN
cord-254419-qw83atrx	69	75	the	the	DT
cord-254419-qw83atrx	69	76	clinical	clinical	JJ
cord-254419-qw83atrx	69	77	picture	picture	NN
cord-254419-qw83atrx	69	78	that	that	WDT
cord-254419-qw83atrx	69	79	leads	lead	VBZ
cord-254419-qw83atrx	69	80	to	to	IN
cord-254419-qw83atrx	69	81	progressive	progressive	JJ
cord-254419-qw83atrx	69	82	multi	multi	JJ
cord-254419-qw83atrx	69	83	-	-	JJ
cord-254419-qw83atrx	69	84	organ	organ	JJ
cord-254419-qw83atrx	69	85	failure	failure	NN
cord-254419-qw83atrx	69	86	in	in	IN
cord-254419-qw83atrx	69	87	a	a	DT
cord-254419-qw83atrx	69	88	small	small	JJ
cord-254419-qw83atrx	69	89	percentage	percentage	NN
cord-254419-qw83atrx	69	90	of	of	IN
cord-254419-qw83atrx	69	91	patients	patient	NNS
cord-254419-qw83atrx	69	92	,	,	,
cord-254419-qw83atrx	69	93	ultimately	ultimately	RB
cord-254419-qw83atrx	69	94	causing	cause	VBG
cord-254419-qw83atrx	69	95	fatalities	fatality	NNS
cord-254419-qw83atrx	69	96	.	.	.
cord-254419-qw83atrx	70	1	Initial	initial	JJ
cord-254419-qw83atrx	70	2	response	response	NN
cord-254419-qw83atrx	70	3	to	to	IN
cord-254419-qw83atrx	70	4	the	the	DT
cord-254419-qw83atrx	70	5	viral	viral	JJ
cord-254419-qw83atrx	70	6	infection	infection	NN
cord-254419-qw83atrx	70	7	is	be	VBZ
cord-254419-qw83atrx	70	8	by	by	IN
cord-254419-qw83atrx	70	9	the	the	DT
cord-254419-qw83atrx	70	10	activation	activation	NN
cord-254419-qw83atrx	70	11	of	of	IN
cord-254419-qw83atrx	70	12	the	the	DT
cord-254419-qw83atrx	70	13	innate	innate	JJ
cord-254419-qw83atrx	70	14	immune	immune	JJ
cord-254419-qw83atrx	70	15	system	system	NN
cord-254419-qw83atrx	70	16	with	with	IN
cord-254419-qw83atrx	70	17	neutrophils	neutrophil	NNS
cord-254419-qw83atrx	70	18	,	,	,
cord-254419-qw83atrx	70	19	macrophages	macrophage	NNS
cord-254419-qw83atrx	70	20	,	,	,
cord-254419-qw83atrx	70	21	and	and	CC
cord-254419-qw83atrx	70	22	cytokines	cytokine	NNS
cord-254419-qw83atrx	70	23	.	.	.
cord-254419-qw83atrx	71	1	This	this	DT
cord-254419-qw83atrx	71	2	results	result	VBZ
cord-254419-qw83atrx	71	3	in	in	IN
cord-254419-qw83atrx	71	4	elevation	elevation	NN
cord-254419-qw83atrx	71	5	of	of	IN
cord-254419-qw83atrx	71	6	acute	acute	JJ
cord-254419-qw83atrx	71	7	-	-	HYPH
cord-254419-qw83atrx	71	8	phase	phase	NN
cord-254419-qw83atrx	71	9	reactants	reactant	NNS
cord-254419-qw83atrx	71	10	like	like	IN
cord-254419-qw83atrx	71	11	C	c	NN
cord-254419-qw83atrx	71	12	reactive	reactive	JJ
cord-254419-qw83atrx	71	13	protein	protein	NN
cord-254419-qw83atrx	71	14	(	(	-LRB-
cord-254419-qw83atrx	71	15	CRP	CRP	NNP
cord-254419-qw83atrx	71	16	)	)	-RRB-
cord-254419-qw83atrx	71	17	,	,	,
cord-254419-qw83atrx	71	18	erythrocyte	erythrocyte	NN
cord-254419-qw83atrx	71	19	sedimentation	sedimentation	NN
cord-254419-qw83atrx	71	20	rate	rate	NN
cord-254419-qw83atrx	71	21	(	(	-LRB-
cord-254419-qw83atrx	71	22	ESR	ESR	NNP
cord-254419-qw83atrx	71	23	)	)	-RRB-
cord-254419-qw83atrx	71	24	,	,	,
cord-254419-qw83atrx	71	25	and	and	CC
cord-254419-qw83atrx	71	26	ferritin	ferritin	NN
cord-254419-qw83atrx	71	27	[	[	-LRB-
cord-254419-qw83atrx	71	28	20	20	CD
cord-254419-qw83atrx	71	29	,	,	,
cord-254419-qw83atrx	71	30	21	21	CD
cord-254419-qw83atrx	71	31	]	]	-RRB-
cord-254419-qw83atrx	71	32	.	.	.
cord-254419-qw83atrx	72	1	This	this	DT
cord-254419-qw83atrx	72	2	can	can	MD
cord-254419-qw83atrx	72	3	be	be	VB
cord-254419-qw83atrx	72	4	considered	consider	VBN
cord-254419-qw83atrx	72	5	as	as	IN
cord-254419-qw83atrx	72	6	the	the	DT
cord-254419-qw83atrx	72	7	first	first	JJ
cord-254419-qw83atrx	72	8	cytokine	cytokine	NN
cord-254419-qw83atrx	72	9	wave	wave	NN
cord-254419-qw83atrx	72	10	or	or	CC
cord-254419-qw83atrx	72	11	hypercytokinemia	hypercytokinemia	NN
cord-254419-qw83atrx	72	12	,	,	,
cord-254419-qw83atrx	72	13	which	which	WDT
cord-254419-qw83atrx	72	14	is	be	VBZ
cord-254419-qw83atrx	72	15	essential	essential	JJ
cord-254419-qw83atrx	72	16	in	in	IN
cord-254419-qw83atrx	72	17	controlling	control	VBG
cord-254419-qw83atrx	72	18	viral	viral	JJ
cord-254419-qw83atrx	72	19	infection	infection	NN
cord-254419-qw83atrx	72	20	.	.	.
cord-254419-qw83atrx	73	1	Dysregulated	Dysregulated	NNP
cord-254419-qw83atrx	73	2	type	type	NN
cord-254419-qw83atrx	73	3	1	1	CD
cord-254419-qw83atrx	73	4	interferon	interferon	NN
cord-254419-qw83atrx	73	5	response	response	NN
cord-254419-qw83atrx	73	6	has	have	VBZ
cord-254419-qw83atrx	73	7	been	be	VBN
cord-254419-qw83atrx	73	8	demonstrated	demonstrate	VBN
cord-254419-qw83atrx	73	9	in	in	IN
cord-254419-qw83atrx	73	10	mice	mice	NN
cord-254419-qw83atrx	73	11	models	model	NNS
cord-254419-qw83atrx	73	12	of	of	IN
cord-254419-qw83atrx	73	13	SARS	SARS	NNP
cord-254419-qw83atrx	73	14	-	-	HYPH
cord-254419-qw83atrx	73	15	CoV	CoV	NNP
cord-254419-qw83atrx	73	16	infection	infection	NN
cord-254419-qw83atrx	73	17	[	[	-LRB-
cord-254419-qw83atrx	73	18	22	22	CD
cord-254419-qw83atrx	73	19	]	]	-RRB-
cord-254419-qw83atrx	73	20	.	.	.
cord-254419-qw83atrx	74	1	It	-PRON-	PRP
cord-254419-qw83atrx	74	2	is	be	VBZ
cord-254419-qw83atrx	74	3	postulated	postulate	VBN
cord-254419-qw83atrx	74	4	that	that	IN
cord-254419-qw83atrx	74	5	similar	similar	JJ
cord-254419-qw83atrx	74	6	suppressed	suppress	VBN
cord-254419-qw83atrx	74	7	type	type	NN
cord-254419-qw83atrx	74	8	1	1	CD
cord-254419-qw83atrx	74	9	interferon	interferon	NN
cord-254419-qw83atrx	74	10	response	response	NN
cord-254419-qw83atrx	74	11	is	be	VBZ
cord-254419-qw83atrx	74	12	present	present	JJ
cord-254419-qw83atrx	74	13	in	in	IN
cord-254419-qw83atrx	74	14	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	74	15	infection	infection	NN
cord-254419-qw83atrx	74	16	,	,	,
cord-254419-qw83atrx	74	17	which	which	WDT
cord-254419-qw83atrx	74	18	when	when	WRB
cord-254419-qw83atrx	74	19	combined	combine	VBN
cord-254419-qw83atrx	74	20	with	with	IN
cord-254419-qw83atrx	74	21	suppression	suppression	NN
cord-254419-qw83atrx	74	22	of	of	IN
cord-254419-qw83atrx	74	23	the	the	DT
cord-254419-qw83atrx	74	24	adaptive	adaptive	JJ
cord-254419-qw83atrx	74	25	immune	immune	JJ
cord-254419-qw83atrx	74	26	system	system	NN
cord-254419-qw83atrx	74	27	[	[	-LRB-
cord-254419-qw83atrx	74	28	T	T	NNP
cord-254419-qw83atrx	74	29	,	,	,
cord-254419-qw83atrx	74	30	B	b	NN
cord-254419-qw83atrx	74	31	and	and	CC
cord-254419-qw83atrx	74	32	natural	natural	JJ
cord-254419-qw83atrx	74	33	killer	killer	NN
cord-254419-qw83atrx	74	34	(	(	-LRB-
cord-254419-qw83atrx	74	35	NK	NK	NNP
cord-254419-qw83atrx	74	36	)	)	-RRB-
cord-254419-qw83atrx	74	37	lymphocytes	lymphocyte	NNS
cord-254419-qw83atrx	74	38	]	]	-RRB-
cord-254419-qw83atrx	74	39	creates	create	VBZ
cord-254419-qw83atrx	74	40	an	an	DT
cord-254419-qw83atrx	74	41	immunodeficient	immunodeficient	JJ
cord-254419-qw83atrx	74	42	state	state	NN
cord-254419-qw83atrx	74	43	that	that	WDT
cord-254419-qw83atrx	74	44	results	result	VBZ
cord-254419-qw83atrx	74	45	in	in	IN
cord-254419-qw83atrx	74	46	poor	poor	JJ
cord-254419-qw83atrx	74	47	and	and	CC
cord-254419-qw83atrx	74	48	delayed	delay	VBN
cord-254419-qw83atrx	74	49	viral	viral	JJ
cord-254419-qw83atrx	74	50	clearance	clearance	NN
cord-254419-qw83atrx	74	51	[	[	-LRB-
cord-254419-qw83atrx	74	52	23	23	CD
cord-254419-qw83atrx	74	53	]	]	-RRB-
cord-254419-qw83atrx	74	54	.	.	.
cord-254419-qw83atrx	75	1	Initial	initial	JJ
cord-254419-qw83atrx	75	2	hypercytokinemia	hypercytokinemia	NN
cord-254419-qw83atrx	75	3	,	,	,
cord-254419-qw83atrx	75	4	suppressed	suppress	VBN
cord-254419-qw83atrx	75	5	type	type	NN
cord-254419-qw83atrx	75	6	1	1	CD
cord-254419-qw83atrx	75	7	interferon	interferon	NN
cord-254419-qw83atrx	75	8	response	response	NN
cord-254419-qw83atrx	75	9	,	,	,
cord-254419-qw83atrx	75	10	and	and	CC
cord-254419-qw83atrx	75	11	the	the	DT
cord-254419-qw83atrx	75	12	inability	inability	NN
cord-254419-qw83atrx	75	13	of	of	IN
cord-254419-qw83atrx	75	14	the	the	DT
cord-254419-qw83atrx	75	15	adaptive	adaptive	JJ
cord-254419-qw83atrx	75	16	immune	immune	JJ
cord-254419-qw83atrx	75	17	system	system	NN
cord-254419-qw83atrx	75	18	to	to	TO
cord-254419-qw83atrx	75	19	clear	clear	VB
cord-254419-qw83atrx	75	20	the	the	DT
cord-254419-qw83atrx	75	21	virus	virus	NN
cord-254419-qw83atrx	75	22	sets	set	VBZ
cord-254419-qw83atrx	75	23	the	the	DT
cord-254419-qw83atrx	75	24	stage	stage	NN
cord-254419-qw83atrx	75	25	for	for	IN
cord-254419-qw83atrx	75	26	hyper	hyper	JJ
cord-254419-qw83atrx	75	27	activation	activation	NN
cord-254419-qw83atrx	75	28	of	of	IN
cord-254419-qw83atrx	75	29	the	the	DT
cord-254419-qw83atrx	75	30	innate	innate	JJ
cord-254419-qw83atrx	75	31	immune	immune	JJ
cord-254419-qw83atrx	75	32	system	system	NN
cord-254419-qw83atrx	75	33	and	and	CC
cord-254419-qw83atrx	75	34	cytokine	cytokine	NN
cord-254419-qw83atrx	75	35	storm	storm	NN
cord-254419-qw83atrx	75	36	in	in	IN
cord-254419-qw83atrx	75	37	some	some	DT
cord-254419-qw83atrx	75	38	patients	patient	NNS
cord-254419-qw83atrx	75	39	.	.	.
cord-254419-qw83atrx	76	1	Cytokine	cytokine	NN
cord-254419-qw83atrx	76	2	dysregulation	dysregulation	NN
cord-254419-qw83atrx	76	3	is	be	VBZ
cord-254419-qw83atrx	76	4	a	a	DT
cord-254419-qw83atrx	76	5	recognized	recognize	VBN
cord-254419-qw83atrx	76	6	feature	feature	NN
cord-254419-qw83atrx	76	7	of	of	IN
cord-254419-qw83atrx	76	8	this	this	DT
cord-254419-qw83atrx	76	9	infection	infection	NN
cord-254419-qw83atrx	76	10	.	.	.
cord-254419-qw83atrx	77	1	Studies	study	NNS
cord-254419-qw83atrx	77	2	in	in	IN
cord-254419-qw83atrx	77	3	hospitalized	hospitalize	VBN
cord-254419-qw83atrx	77	4	patients	patient	NNS
cord-254419-qw83atrx	77	5	have	have	VBP
cord-254419-qw83atrx	77	6	shown	show	VBN
cord-254419-qw83atrx	77	7	that	that	IN
cord-254419-qw83atrx	77	8	plasma	plasma	NN
cord-254419-qw83atrx	77	9	interleukin1	interleukin1	NN
cord-254419-qw83atrx	77	10	beta(IL1b	beta(IL1b	NNP
cord-254419-qw83atrx	77	11	)	)	-RRB-
cord-254419-qw83atrx	77	12	,	,	,
cord-254419-qw83atrx	77	13	IL-1	IL-1	NNP
cord-254419-qw83atrx	77	14	receptor	receptor	NN
cord-254419-qw83atrx	77	15	antagonist	antagonist	NN
cord-254419-qw83atrx	77	16	(	(	-LRB-
cord-254419-qw83atrx	77	17	IL1RA	IL1RA	NNP
cord-254419-qw83atrx	77	18	)	)	-RRB-
cord-254419-qw83atrx	77	19	,	,	,
cord-254419-qw83atrx	77	20	IL7	IL7	NNP
cord-254419-qw83atrx	77	21	,	,	,
cord-254419-qw83atrx	77	22	IL8	IL8	NNP
cord-254419-qw83atrx	77	23	,	,	,
cord-254419-qw83atrx	77	24	IL9	il9	NN
cord-254419-qw83atrx	77	25	,	,	,
cord-254419-qw83atrx	77	26	IL10	IL10	NNP
cord-254419-qw83atrx	77	27	,	,	,
cord-254419-qw83atrx	77	28	granulocyte	granulocyte	NN
cord-254419-qw83atrx	77	29	colony	colony	NN
cord-254419-qw83atrx	77	30	-	-	HYPH
cord-254419-qw83atrx	77	31	stimulating	stimulate	VBG
cord-254419-qw83atrx	77	32	factor	factor	NN
cord-254419-qw83atrx	77	33	(	(	-LRB-
cord-254419-qw83atrx	77	34	GCSF	GCSF	NNP
cord-254419-qw83atrx	77	35	)	)	-RRB-
cord-254419-qw83atrx	77	36	,	,	,
cord-254419-qw83atrx	77	37	granulocyte	granulocyte	NNP
cord-254419-qw83atrx	77	38	monocyte	monocyte	NNP
cord-254419-qw83atrx	77	39	colony	colony	NN
cord-254419-qw83atrx	77	40	-	-	HYPH
cord-254419-qw83atrx	77	41	stimulating	stimulate	VBG
cord-254419-qw83atrx	77	42	factor	factor	NN
cord-254419-qw83atrx	77	43	(	(	-LRB-
cord-254419-qw83atrx	77	44	GMCSF	GMCSF	NNP
cord-254419-qw83atrx	77	45	)	)	-RRB-
cord-254419-qw83atrx	77	46	,	,	,
cord-254419-qw83atrx	77	47	interferon	interferon	NN
cord-254419-qw83atrx	77	48	gamma	gamma	NN
cord-254419-qw83atrx	77	49	(	(	-LRB-
cord-254419-qw83atrx	77	50	IFNc	IFNc	NNP
cord-254419-qw83atrx	77	51	)	)	-RRB-
cord-254419-qw83atrx	77	52	,	,	,
cord-254419-qw83atrx	77	53	interferon	interferon	NN
cord-254419-qw83atrx	77	54	gamma	gamma	NN
cord-254419-qw83atrx	77	55	-	-	HYPH
cord-254419-qw83atrx	77	56	induced	induce	VBN
cord-254419-qw83atrx	77	57	protein	protein	NN
cord-254419-qw83atrx	77	58	10	10	CD
cord-254419-qw83atrx	77	59	(	(	-LRB-
cord-254419-qw83atrx	77	60	IP10	IP10	NNP
cord-254419-qw83atrx	77	61	)	)	-RRB-
cord-254419-qw83atrx	77	62	,	,	,
cord-254419-qw83atrx	77	63	monocyte	monocyte	NNP
cord-254419-qw83atrx	77	64	chemoattractant	chemoattractant	NNP
cord-254419-qw83atrx	77	65	protein	protein	NNP
cord-254419-qw83atrx	77	66	1	1	CD
cord-254419-qw83atrx	77	67	(	(	-LRB-
cord-254419-qw83atrx	77	68	MCP1	MCP1	NNP
cord-254419-qw83atrx	77	69	)	)	-RRB-
cord-254419-qw83atrx	77	70	,	,	,
cord-254419-qw83atrx	77	71	macrophage	macrophage	NN
cord-254419-qw83atrx	77	72	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	77	73	protein	protein	NN
cord-254419-qw83atrx	77	74	1	1	CD
cord-254419-qw83atrx	77	75	alpha	alpha	NN
cord-254419-qw83atrx	77	76	(	(	-LRB-
cord-254419-qw83atrx	77	77	MIP1A	MIP1A	NNP
cord-254419-qw83atrx	77	78	)	)	-RRB-
cord-254419-qw83atrx	77	79	,	,	,
cord-254419-qw83atrx	77	80	macrophage	macrophage	NN
cord-254419-qw83atrx	77	81	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	77	82	protein	protein	NN
cord-254419-qw83atrx	77	83	1	1	CD
cord-254419-qw83atrx	77	84	beta	beta	NN
cord-254419-qw83atrx	77	85	(	(	-LRB-
cord-254419-qw83atrx	77	86	MIP1B	MIP1B	NNP
cord-254419-qw83atrx	77	87	)	)	-RRB-
cord-254419-qw83atrx	77	88	,	,	,
cord-254419-qw83atrx	77	89	platelet	platelet	NN
cord-254419-qw83atrx	77	90	-	-	HYPH
cord-254419-qw83atrx	77	91	derived	derive	VBN
cord-254419-qw83atrx	77	92	growth	growth	NN
cord-254419-qw83atrx	77	93	factor	factor	NN
cord-254419-qw83atrx	77	94	(	(	-LRB-
cord-254419-qw83atrx	77	95	PDGF	PDGF	NNP
cord-254419-qw83atrx	77	96	)	)	-RRB-
cord-254419-qw83atrx	77	97	,	,	,
cord-254419-qw83atrx	77	98	tumor	tumor	NN
cord-254419-qw83atrx	77	99	necrosis	necrosis	NN
cord-254419-qw83atrx	77	100	factor	factor	NN
cord-254419-qw83atrx	77	101	alpha	alpha	NN
cord-254419-qw83atrx	77	102	(	(	-LRB-
cord-254419-qw83atrx	77	103	TNFa	TNFa	NNP
cord-254419-qw83atrx	77	104	)	)	-RRB-
cord-254419-qw83atrx	77	105	,	,	,
cord-254419-qw83atrx	77	106	and	and	CC
cord-254419-qw83atrx	77	107	vascular	vascular	JJ
cord-254419-qw83atrx	77	108	endothelial	endothelial	JJ
cord-254419-qw83atrx	77	109	growth	growth	NN
cord-254419-qw83atrx	77	110	factor	factor	NN
cord-254419-qw83atrx	77	111	(	(	-LRB-
cord-254419-qw83atrx	77	112	VEGF	VEGF	NNP
cord-254419-qw83atrx	77	113	)	)	-RRB-
cord-254419-qw83atrx	77	114	concentrations	concentration	NNS
cord-254419-qw83atrx	77	115	on	on	IN
cord-254419-qw83atrx	77	116	admission	admission	NN
cord-254419-qw83atrx	77	117	were	be	VBD
cord-254419-qw83atrx	77	118	higher	high	JJR
cord-254419-qw83atrx	77	119	in	in	IN
cord-254419-qw83atrx	77	120	patients	patient	NNS
cord-254419-qw83atrx	77	121	with	with	IN
cord-254419-qw83atrx	77	122	COVID-19	covid-19	JJ
cord-254419-qw83atrx	77	123	infection	infection	NN
cord-254419-qw83atrx	77	124	compared	compare	VBN
cord-254419-qw83atrx	77	125	to	to	IN
cord-254419-qw83atrx	77	126	healthy	healthy	JJ
cord-254419-qw83atrx	77	127	adults	adult	NNS
cord-254419-qw83atrx	77	128	[	[	-LRB-
cord-254419-qw83atrx	77	129	21	21	CD
cord-254419-qw83atrx	77	130	]	]	-RRB-
cord-254419-qw83atrx	77	131	.	.	.
cord-254419-qw83atrx	78	1	In	in	IN
cord-254419-qw83atrx	78	2	the	the	DT
cord-254419-qw83atrx	78	3	same	same	JJ
cord-254419-qw83atrx	78	4	study	study	NN
cord-254419-qw83atrx	78	5	,	,	,
cord-254419-qw83atrx	78	6	plasma	plasma	NN
cord-254419-qw83atrx	78	7	concentrations	concentration	NNS
cord-254419-qw83atrx	78	8	of	of	IN
cord-254419-qw83atrx	78	9	IL2	IL2	NNP
cord-254419-qw83atrx	78	10	,	,	,
cord-254419-qw83atrx	78	11	IL7	IL7	NNP
cord-254419-qw83atrx	78	12	,	,	,
cord-254419-qw83atrx	78	13	IL10	IL10	NNP
cord-254419-qw83atrx	78	14	,	,	,
cord-254419-qw83atrx	78	15	GCSF	GCSF	NNP
cord-254419-qw83atrx	78	16	,	,	,
cord-254419-qw83atrx	78	17	IP10	IP10	NNP
cord-254419-qw83atrx	78	18	,	,	,
cord-254419-qw83atrx	78	19	MCP1	MCP1	NNP
cord-254419-qw83atrx	78	20	,	,	,
cord-254419-qw83atrx	78	21	MIP1A	mip1a	CD
cord-254419-qw83atrx	78	22	,	,	,
cord-254419-qw83atrx	78	23	and	and	CC
cord-254419-qw83atrx	78	24	TNFa	TNFa	NNS
cord-254419-qw83atrx	78	25	were	be	VBD
cord-254419-qw83atrx	78	26	found	find	VBN
cord-254419-qw83atrx	78	27	to	to	TO
cord-254419-qw83atrx	78	28	be	be	VB
cord-254419-qw83atrx	78	29	higher	high	JJR
cord-254419-qw83atrx	78	30	in	in	IN
cord-254419-qw83atrx	78	31	patients	patient	NNS
cord-254419-qw83atrx	78	32	needing	need	VBG
cord-254419-qw83atrx	78	33	ICU	ICU	NNP
cord-254419-qw83atrx	78	34	admission	admission	NN
cord-254419-qw83atrx	78	35	compared	compare	VBN
cord-254419-qw83atrx	78	36	to	to	IN
cord-254419-qw83atrx	78	37	those	those	DT
cord-254419-qw83atrx	78	38	who	who	WP
cord-254419-qw83atrx	78	39	did	do	VBD
cord-254419-qw83atrx	78	40	not	not	RB
cord-254419-qw83atrx	78	41	.	.	.
cord-254419-qw83atrx	79	1	Disease	disease	NN
cord-254419-qw83atrx	79	2	severity	severity	NN
cord-254419-qw83atrx	79	3	has	have	VBZ
cord-254419-qw83atrx	79	4	been	be	VBN
cord-254419-qw83atrx	79	5	found	find	VBN
cord-254419-qw83atrx	79	6	to	to	TO
cord-254419-qw83atrx	79	7	positively	positively	RB
cord-254419-qw83atrx	79	8	correlate	correlate	VB
cord-254419-qw83atrx	79	9	with	with	IN
cord-254419-qw83atrx	79	10	serum	serum	NN
cord-254419-qw83atrx	79	11	levels	level	NNS
cord-254419-qw83atrx	79	12	of	of	IN
cord-254419-qw83atrx	79	13	TNFa	TNFa	NNS
cord-254419-qw83atrx	79	14	,	,	,
cord-254419-qw83atrx	79	15	IL6	IL6	NNP
cord-254419-qw83atrx	79	16	,	,	,
cord-254419-qw83atrx	79	17	and	and	CC
cord-254419-qw83atrx	79	18	IL10	IL10	NNP
cord-254419-qw83atrx	79	19	,	,	,
cord-254419-qw83atrx	79	20	and	and	CC
cord-254419-qw83atrx	79	21	there	there	EX
cord-254419-qw83atrx	79	22	was	be	VBD
cord-254419-qw83atrx	79	23	also	also	RB
cord-254419-qw83atrx	79	24	a	a	DT
cord-254419-qw83atrx	79	25	strong	strong	JJ
cord-254419-qw83atrx	79	26	negative	negative	JJ
cord-254419-qw83atrx	79	27	correlation	correlation	NN
cord-254419-qw83atrx	79	28	of	of	IN
cord-254419-qw83atrx	79	29	levels	level	NNS
cord-254419-qw83atrx	79	30	of	of	IN
cord-254419-qw83atrx	79	31	TNFa	TNFa	NNS
cord-254419-qw83atrx	79	32	and	and	CC
cord-254419-qw83atrx	79	33	IL6	il6	NN
cord-254419-qw83atrx	79	34	with	with	IN
cord-254419-qw83atrx	79	35	the	the	DT
cord-254419-qw83atrx	79	36	number	number	NN
cord-254419-qw83atrx	79	37	of	of	IN
cord-254419-qw83atrx	79	38	CD4	CD4	NNP
cord-254419-qw83atrx	79	39	?	?	.
cord-254419-qw83atrx	79	40	,	,	,
cord-254419-qw83atrx	79	41	CD8	CD8	NNP
cord-254419-qw83atrx	79	42	?	?	.
cord-254419-qw83atrx	80	1	T	T	NNP
cord-254419-qw83atrx	80	2	lymphocytes	lymphocyte	NNS
cord-254419-qw83atrx	80	3	[	[	-LRB-
cord-254419-qw83atrx	80	4	24	24	CD
cord-254419-qw83atrx	80	5	]	]	-RRB-
cord-254419-qw83atrx	80	6	.	.	.
cord-254419-qw83atrx	81	1	In	in	IN
cord-254419-qw83atrx	81	2	a	a	DT
cord-254419-qw83atrx	81	3	study	study	NN
cord-254419-qw83atrx	81	4	by	by	IN
cord-254419-qw83atrx	81	5	Diao	Diao	NNP
cord-254419-qw83atrx	81	6	et	et	NNP
cord-254419-qw83atrx	81	7	al	al	NNP
cord-254419-qw83atrx	81	8	.	.	NNP
cord-254419-qw83atrx	81	9	,	,	,
cord-254419-qw83atrx	81	10	higher	high	JJR
cord-254419-qw83atrx	81	11	levels	level	NNS
cord-254419-qw83atrx	81	12	of	of	IN
cord-254419-qw83atrx	81	13	the	the	DT
cord-254419-qw83atrx	81	14	exhausted	exhausted	JJ
cord-254419-qw83atrx	81	15	marker	marker	NN
cord-254419-qw83atrx	81	16	PD-1	PD-1	NNP
cord-254419-qw83atrx	81	17	were	be	VBD
cord-254419-qw83atrx	81	18	seen	see	VBN
cord-254419-qw83atrx	81	19	in	in	IN
cord-254419-qw83atrx	81	20	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	81	21	patients	patient	NNS
cord-254419-qw83atrx	81	22	,	,	,
cord-254419-qw83atrx	81	23	suggesting	suggest	VBG
cord-254419-qw83atrx	81	24	not	not	RB
cord-254419-qw83atrx	81	25	only	only	RB
cord-254419-qw83atrx	81	26	that	that	IN
cord-254419-qw83atrx	81	27	lymphocyte	lymphocyte	NN
cord-254419-qw83atrx	81	28	numbers	number	NNS
cord-254419-qw83atrx	81	29	are	be	VBP
cord-254419-qw83atrx	81	30	lower	low	JJR
cord-254419-qw83atrx	81	31	,	,	,
cord-254419-qw83atrx	81	32	but	but	CC
cord-254419-qw83atrx	81	33	existing	exist	VBG
cord-254419-qw83atrx	81	34	T	t	NN
cord-254419-qw83atrx	81	35	cells	cell	NNS
cord-254419-qw83atrx	81	36	are	be	VBP
cord-254419-qw83atrx	81	37	functionally	functionally	RB
cord-254419-qw83atrx	81	38	exhausted	exhausted	JJ
cord-254419-qw83atrx	81	39	.	.	.
cord-254419-qw83atrx	82	1	In	in	IN
cord-254419-qw83atrx	82	2	a	a	DT
cord-254419-qw83atrx	82	3	larger	large	JJR
cord-254419-qw83atrx	82	4	study	study	NN
cord-254419-qw83atrx	82	5	of	of	IN
cord-254419-qw83atrx	82	6	452	452	CD
cord-254419-qw83atrx	82	7	patients	patient	NNS
cord-254419-qw83atrx	82	8	,	,	,
cord-254419-qw83atrx	82	9	of	of	IN
cord-254419-qw83atrx	82	10	whom	whom	WP
cord-254419-qw83atrx	82	11	286	286	CD
cord-254419-qw83atrx	82	12	were	be	VBD
cord-254419-qw83atrx	82	13	classified	classify	VBN
cord-254419-qw83atrx	82	14	as	as	IN
cord-254419-qw83atrx	82	15	having	have	VBG
cord-254419-qw83atrx	82	16	severe	severe	JJ
cord-254419-qw83atrx	82	17	disease	disease	NN
cord-254419-qw83atrx	82	18	,	,	,
cord-254419-qw83atrx	82	19	dysregulation	dysregulation	NN
cord-254419-qw83atrx	82	20	of	of	IN
cord-254419-qw83atrx	82	21	the	the	DT
cord-254419-qw83atrx	82	22	immune	immune	JJ
cord-254419-qw83atrx	82	23	system	system	NN
cord-254419-qw83atrx	82	24	was	be	VBD
cord-254419-qw83atrx	82	25	seen	see	VBN
cord-254419-qw83atrx	82	26	with	with	IN
cord-254419-qw83atrx	82	27	a	a	DT
cord-254419-qw83atrx	82	28	high	high	JJ
cord-254419-qw83atrx	82	29	leucocyte	leucocyte	NN
cord-254419-qw83atrx	82	30	count	count	NN
cord-254419-qw83atrx	82	31	and	and	CC
cord-254419-qw83atrx	82	32	high	high	JJ
cord-254419-qw83atrx	82	33	neutrophil	neutrophil	NN
cord-254419-qw83atrx	82	34	-	-	HYPH
cord-254419-qw83atrx	82	35	to	to	IN
cord-254419-qw83atrx	82	36	-	-	HYPH
cord-254419-qw83atrx	82	37	lymphocyte	lymphocyte	NN
cord-254419-qw83atrx	82	38	ratio	ratio	NN
cord-254419-qw83atrx	82	39	[	[	-LRB-
cord-254419-qw83atrx	82	40	25	25	CD
cord-254419-qw83atrx	82	41	]	]	-RRB-
cord-254419-qw83atrx	82	42	.	.	.
cord-254419-qw83atrx	83	1	Regulatory	regulatory	JJ
cord-254419-qw83atrx	83	2	T	t	NN
cord-254419-qw83atrx	83	3	cells	cell	NNS
cord-254419-qw83atrx	83	4	that	that	WDT
cord-254419-qw83atrx	83	5	help	help	VBP
cord-254419-qw83atrx	83	6	control	control	VB
cord-254419-qw83atrx	83	7	inflammation	inflammation	NN
cord-254419-qw83atrx	83	8	were	be	VBD
cord-254419-qw83atrx	83	9	also	also	RB
cord-254419-qw83atrx	83	10	found	find	VBN
cord-254419-qw83atrx	83	11	to	to	TO
cord-254419-qw83atrx	83	12	be	be	VB
cord-254419-qw83atrx	83	13	low	low	JJ
cord-254419-qw83atrx	83	14	in	in	IN
cord-254419-qw83atrx	83	15	this	this	DT
cord-254419-qw83atrx	83	16	study	study	NN
cord-254419-qw83atrx	83	17	,	,	,
cord-254419-qw83atrx	83	18	especially	especially	RB
cord-254419-qw83atrx	83	19	in	in	IN
cord-254419-qw83atrx	83	20	patients	patient	NNS
cord-254419-qw83atrx	83	21	with	with	IN
cord-254419-qw83atrx	83	22	severe	severe	JJ
cord-254419-qw83atrx	83	23	disease	disease	NN
cord-254419-qw83atrx	83	24	.	.	.
cord-254419-qw83atrx	84	1	These	these	DT
cord-254419-qw83atrx	84	2	mechanisms	mechanism	NNS
cord-254419-qw83atrx	84	3	partly	partly	RB
cord-254419-qw83atrx	84	4	explain	explain	VBP
cord-254419-qw83atrx	84	5	the	the	DT
cord-254419-qw83atrx	84	6	unabated	unabated	JJ
cord-254419-qw83atrx	84	7	progression	progression	NN
cord-254419-qw83atrx	84	8	of	of	IN
cord-254419-qw83atrx	84	9	the	the	DT
cord-254419-qw83atrx	84	10	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	84	11	process	process	NN
cord-254419-qw83atrx	84	12	,	,	,
cord-254419-qw83atrx	84	13	the	the	DT
cord-254419-qw83atrx	84	14	ongoing	ongoing	JJ
cord-254419-qw83atrx	84	15	cytokine	cytokine	NN
cord-254419-qw83atrx	84	16	storm	storm	NN
cord-254419-qw83atrx	84	17	,	,	,
cord-254419-qw83atrx	84	18	and	and	CC
cord-254419-qw83atrx	84	19	the	the	DT
cord-254419-qw83atrx	84	20	progressive	progressive	JJ
cord-254419-qw83atrx	84	21	tissue	tissue	NN
cord-254419-qw83atrx	84	22	damage	damage	NN
cord-254419-qw83atrx	84	23	.	.	.
cord-254419-qw83atrx	85	1	The	the	DT
cord-254419-qw83atrx	85	2	similarity	similarity	NN
cord-254419-qw83atrx	85	3	of	of	IN
cord-254419-qw83atrx	85	4	severe	severe	JJ
cord-254419-qw83atrx	85	5	COVID-19	covid-19	JJ
cord-254419-qw83atrx	85	6	disease	disease	NN
cord-254419-qw83atrx	85	7	to	to	IN
cord-254419-qw83atrx	85	8	thrombotic	thrombotic	JJ
cord-254419-qw83atrx	85	9	microangiopathic	microangiopathic	JJ
cord-254419-qw83atrx	85	10	anemia	anemia	NN
cord-254419-qw83atrx	85	11	with	with	IN
cord-254419-qw83atrx	85	12	elevated	elevated	JJ
cord-254419-qw83atrx	85	13	lactate	lactate	NN
cord-254419-qw83atrx	85	14	dehydrogenase	dehydrogenase	NN
cord-254419-qw83atrx	85	15	(	(	-LRB-
cord-254419-qw83atrx	85	16	LDH	LDH	NNP
cord-254419-qw83atrx	85	17	)	)	-RRB-
cord-254419-qw83atrx	85	18	,	,	,
cord-254419-qw83atrx	85	19	D	d	NN
cord-254419-qw83atrx	85	20	-	-	HYPH
cord-254419-qw83atrx	85	21	dimer	dimer	NN
cord-254419-qw83atrx	85	22	and	and	CC
cord-254419-qw83atrx	85	23	bilirubin	bilirubin	NN
cord-254419-qw83atrx	85	24	,	,	,
cord-254419-qw83atrx	85	25	decreased	decrease	VBD
cord-254419-qw83atrx	85	26	platelets	platelet	NNS
cord-254419-qw83atrx	85	27	,	,	,
cord-254419-qw83atrx	85	28	anemia	anemia	NN
cord-254419-qw83atrx	85	29	,	,	,
cord-254419-qw83atrx	85	30	and	and	CC
cord-254419-qw83atrx	85	31	renal	renal	JJ
cord-254419-qw83atrx	85	32	and	and	CC
cord-254419-qw83atrx	85	33	cardiac	cardiac	JJ
cord-254419-qw83atrx	85	34	injury	injury	NN
cord-254419-qw83atrx	85	35	is	be	VBZ
cord-254419-qw83atrx	85	36	suggestive	suggestive	JJ
cord-254419-qw83atrx	85	37	of	of	IN
cord-254419-qw83atrx	85	38	excessive	excessive	JJ
cord-254419-qw83atrx	85	39	complement	complement	NN
cord-254419-qw83atrx	85	40	activation	activation	NN
cord-254419-qw83atrx	85	41	.	.	.
cord-254419-qw83atrx	86	1	Hence	hence	RB
cord-254419-qw83atrx	86	2	,	,	,
cord-254419-qw83atrx	86	3	complement	complement	VB
cord-254419-qw83atrx	86	4	inhibition	inhibition	NN
cord-254419-qw83atrx	86	5	as	as	IN
cord-254419-qw83atrx	86	6	a	a	DT
cord-254419-qw83atrx	86	7	therapeutic	therapeutic	JJ
cord-254419-qw83atrx	86	8	option	option	NN
cord-254419-qw83atrx	86	9	has	have	VBZ
cord-254419-qw83atrx	86	10	also	also	RB
cord-254419-qw83atrx	86	11	been	be	VBN
cord-254419-qw83atrx	86	12	suggested	suggest	VBN
cord-254419-qw83atrx	86	13	[	[	-LRB-
cord-254419-qw83atrx	86	14	26	26	CD
cord-254419-qw83atrx	86	15	]	]	-RRB-
cord-254419-qw83atrx	86	16	.	.	.
cord-254419-qw83atrx	87	1	Another	another	DT
cord-254419-qw83atrx	87	2	multi	multi	JJ
cord-254419-qw83atrx	87	3	-	-	JJ
cord-254419-qw83atrx	87	4	center	center	JJ
cord-254419-qw83atrx	87	5	study	study	NN
cord-254419-qw83atrx	87	6	conducted	conduct	VBN
cord-254419-qw83atrx	87	7	in	in	IN
cord-254419-qw83atrx	87	8	Europe	Europe	NNP
cord-254419-qw83atrx	87	9	investigated	investigate	VBD
cord-254419-qw83atrx	87	10	immune	immune	JJ
cord-254419-qw83atrx	87	11	dysregulation	dysregulation	NN
cord-254419-qw83atrx	87	12	in	in	IN
cord-254419-qw83atrx	87	13	54	54	CD
cord-254419-qw83atrx	87	14	patients	patient	NNS
cord-254419-qw83atrx	87	15	(	(	-LRB-
cord-254419-qw83atrx	87	16	28	28	CD
cord-254419-qw83atrx	87	17	with	with	IN
cord-254419-qw83atrx	87	18	severe	severe	JJ
cord-254419-qw83atrx	87	19	respiratory	respiratory	JJ
cord-254419-qw83atrx	87	20	failure	failure	NN
cord-254419-qw83atrx	87	21	)	)	-RRB-
cord-254419-qw83atrx	87	22	.	.	.
cord-254419-qw83atrx	88	1	Clinical	clinical	JJ
cord-254419-qw83atrx	88	2	features	feature	NNS
cord-254419-qw83atrx	88	3	suggestive	suggestive	JJ
cord-254419-qw83atrx	88	4	of	of	IN
cord-254419-qw83atrx	88	5	macrophage	macrophage	NN
cord-254419-qw83atrx	88	6	activation	activation	NN
cord-254419-qw83atrx	88	7	syndrome	syndrome	NN
cord-254419-qw83atrx	88	8	(	(	-LRB-
cord-254419-qw83atrx	88	9	MAS	MAS	NNP
cord-254419-qw83atrx	88	10	)	)	-RRB-
cord-254419-qw83atrx	88	11	associated	associate	VBN
cord-254419-qw83atrx	88	12	with	with	IN
cord-254419-qw83atrx	88	13	low	low	JJ
cord-254419-qw83atrx	88	14	CD4	CD4	NNP
cord-254419-qw83atrx	88	15	?	?	.
cord-254419-qw83atrx	89	1	T	t	NN
cord-254419-qw83atrx	89	2	-	-	HYPH
cord-254419-qw83atrx	89	3	cells	cell	NNS
cord-254419-qw83atrx	89	4	,	,	,
cord-254419-qw83atrx	89	5	CD19	CD19	NNP
cord-254419-qw83atrx	89	6	?	?	.
cord-254419-qw83atrx	89	7	B	b	NN
cord-254419-qw83atrx	89	8	-	-	HYPH
cord-254419-qw83atrx	89	9	cells	cell	NNS
cord-254419-qw83atrx	89	10	,	,	,
cord-254419-qw83atrx	89	11	and	and	CC
cord-254419-qw83atrx	89	12	NK	NK	NNP
cord-254419-qw83atrx	89	13	cells	cell	NNS
cord-254419-qw83atrx	89	14	were	be	VBD
cord-254419-qw83atrx	89	15	found	find	VBN
cord-254419-qw83atrx	89	16	in	in	IN
cord-254419-qw83atrx	89	17	all	all	PDT
cord-254419-qw83atrx	89	18	the	the	DT
cord-254419-qw83atrx	89	19	patients	patient	NNS
cord-254419-qw83atrx	89	20	.	.	.
cord-254419-qw83atrx	90	1	Sustained	sustained	JJ
cord-254419-qw83atrx	90	2	elevation	elevation	NN
cord-254419-qw83atrx	90	3	of	of	IN
cord-254419-qw83atrx	90	4	TNFa	TNFa	NNS
cord-254419-qw83atrx	90	5	and	and	CC
cord-254419-qw83atrx	90	6	IL-6	IL-6	NNP
cord-254419-qw83atrx	90	7	was	be	VBD
cord-254419-qw83atrx	90	8	also	also	RB
cord-254419-qw83atrx	90	9	found	find	VBN
cord-254419-qw83atrx	90	10	,	,	,
cord-254419-qw83atrx	90	11	representing	represent	VBG
cord-254419-qw83atrx	90	12	a	a	DT
cord-254419-qw83atrx	90	13	hyperactive	hyperactive	JJ
cord-254419-qw83atrx	90	14	monocyte	monocyte	NNP
cord-254419-qw83atrx	90	15	macrophage	macrophage	NN
cord-254419-qw83atrx	90	16	system	system	NN
cord-254419-qw83atrx	90	17	[	[	-LRB-
cord-254419-qw83atrx	90	18	11	11	CD
cord-254419-qw83atrx	90	19	]	]	-RRB-
cord-254419-qw83atrx	90	20	.	.	.
cord-254419-qw83atrx	91	1	In	in	IN
cord-254419-qw83atrx	91	2	another	another	DT
cord-254419-qw83atrx	91	3	study	study	NN
cord-254419-qw83atrx	91	4	,	,	,
cord-254419-qw83atrx	91	5	lymphocyte	lymphocyte	NN
cord-254419-qw83atrx	91	6	subset	subset	VBN
cord-254419-qw83atrx	91	7	analysis	analysis	NN
cord-254419-qw83atrx	91	8	in	in	IN
cord-254419-qw83atrx	91	9	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	91	10	patients	patient	NNS
cord-254419-qw83atrx	91	11	showed	show	VBD
cord-254419-qw83atrx	91	12	a	a	DT
cord-254419-qw83atrx	91	13	statistically	statistically	RB
cord-254419-qw83atrx	91	14	significant	significant	JJ
cord-254419-qw83atrx	91	15	lower	low	JJR
cord-254419-qw83atrx	91	16	number	number	NN
cord-254419-qw83atrx	91	17	of	of	IN
cord-254419-qw83atrx	91	18	CD4	CD4	NNP
cord-254419-qw83atrx	91	19	?	?	.
cord-254419-qw83atrx	92	1	helper	helper	NNP
cord-254419-qw83atrx	92	2	T	T	NNP
cord-254419-qw83atrx	92	3	cells	cell	NNS
cord-254419-qw83atrx	92	4	,	,	,
cord-254419-qw83atrx	92	5	CD8	CD8	NNP
cord-254419-qw83atrx	92	6	?	?	.
cord-254419-qw83atrx	93	1	cytotoxic	cytotoxic	JJ
cord-254419-qw83atrx	93	2	T	T	NNP
cord-254419-qw83atrx	93	3	cells	cell	NNS
cord-254419-qw83atrx	93	4	,	,	,
cord-254419-qw83atrx	93	5	NK	NK	NNP
cord-254419-qw83atrx	93	6	cells	cell	NNS
cord-254419-qw83atrx	93	7	,	,	,
cord-254419-qw83atrx	93	8	and	and	CC
cord-254419-qw83atrx	93	9	B	b	NN
cord-254419-qw83atrx	93	10	cells	cell	NNS
cord-254419-qw83atrx	93	11	when	when	WRB
cord-254419-qw83atrx	93	12	compared	compare	VBN
cord-254419-qw83atrx	93	13	to	to	IN
cord-254419-qw83atrx	93	14	healthy	healthy	JJ
cord-254419-qw83atrx	93	15	controls	control	NNS
cord-254419-qw83atrx	93	16	[	[	-LRB-
cord-254419-qw83atrx	93	17	27	27	CD
cord-254419-qw83atrx	93	18	]	]	-RRB-
cord-254419-qw83atrx	93	19	.	.	.
cord-254419-qw83atrx	94	1	In	in	IN
cord-254419-qw83atrx	94	2	this	this	DT
cord-254419-qw83atrx	94	3	study	study	NN
cord-254419-qw83atrx	94	4	,	,	,
cord-254419-qw83atrx	94	5	patients	patient	NNS
cord-254419-qw83atrx	94	6	with	with	IN
cord-254419-qw83atrx	94	7	severe	severe	JJ
cord-254419-qw83atrx	94	8	disease	disease	NN
cord-254419-qw83atrx	94	9	(	(	-LRB-
cord-254419-qw83atrx	94	10	32	32	CD
cord-254419-qw83atrx	94	11	%	%	NN
cord-254419-qw83atrx	94	12	cases	case	NNS
cord-254419-qw83atrx	94	13	)	)	-RRB-
cord-254419-qw83atrx	94	14	had	have	VBD
cord-254419-qw83atrx	94	15	significantly	significantly	RB
cord-254419-qw83atrx	94	16	lower	low	JJR
cord-254419-qw83atrx	94	17	CD4	CD4	NNP
cord-254419-qw83atrx	94	18	?	?	.
cord-254419-qw83atrx	95	1	and	and	CC
cord-254419-qw83atrx	95	2	CD8	CD8	NNP
cord-254419-qw83atrx	95	3	?	?	.
cord-254419-qw83atrx	96	1	T	T	NNP
cord-254419-qw83atrx	96	2	cells	cell	NNS
cord-254419-qw83atrx	96	3	and	and	CC
cord-254419-qw83atrx	96	4	B	b	NN
cord-254419-qw83atrx	96	5	cells	cell	NNS
cord-254419-qw83atrx	96	6	,	,	,
cord-254419-qw83atrx	96	7	although	although	IN
cord-254419-qw83atrx	96	8	no	no	DT
cord-254419-qw83atrx	96	9	significant	significant	JJ
cord-254419-qw83atrx	96	10	differences	difference	NNS
cord-254419-qw83atrx	96	11	were	be	VBD
cord-254419-qw83atrx	96	12	seen	see	VBN
cord-254419-qw83atrx	96	13	in	in	IN
cord-254419-qw83atrx	96	14	the	the	DT
cord-254419-qw83atrx	96	15	CD4	CD4	NNP
cord-254419-qw83atrx	96	16	/	/	SYM
cord-254419-qw83atrx	96	17	CD8	CD8	NNP
cord-254419-qw83atrx	96	18	ratio	ratio	NN
cord-254419-qw83atrx	96	19	or	or	CC
cord-254419-qw83atrx	96	20	NK	NK	NNP
cord-254419-qw83atrx	96	21	cell	cell	NN
cord-254419-qw83atrx	96	22	numbers	number	NNS
cord-254419-qw83atrx	97	1	when	when	WRB
cord-254419-qw83atrx	97	2	compared	compare	VBN
cord-254419-qw83atrx	97	3	to	to	IN
cord-254419-qw83atrx	97	4	those	those	DT
cord-254419-qw83atrx	97	5	with	with	IN
cord-254419-qw83atrx	97	6	mild	mild	JJ
cord-254419-qw83atrx	97	7	symptoms	symptom	NNS
cord-254419-qw83atrx	97	8	.	.	.
cord-254419-qw83atrx	98	1	These	these	DT
cord-254419-qw83atrx	98	2	studies	study	NNS
cord-254419-qw83atrx	98	3	suggest	suggest	VBP
cord-254419-qw83atrx	98	4	that	that	IN
cord-254419-qw83atrx	98	5	in	in	IN
cord-254419-qw83atrx	98	6	this	this	DT
cord-254419-qw83atrx	98	7	disease	disease	NN
cord-254419-qw83atrx	98	8	,	,	,
cord-254419-qw83atrx	98	9	a	a	DT
cord-254419-qw83atrx	98	10	suppression	suppression	NN
cord-254419-qw83atrx	98	11	of	of	IN
cord-254419-qw83atrx	98	12	the	the	DT
cord-254419-qw83atrx	98	13	adaptive	adaptive	JJ
cord-254419-qw83atrx	98	14	immune	immune	JJ
cord-254419-qw83atrx	98	15	system	system	NN
cord-254419-qw83atrx	98	16	along	along	IN
cord-254419-qw83atrx	98	17	with	with	IN
cord-254419-qw83atrx	98	18	hyper	hyper	JJ
cord-254419-qw83atrx	98	19	activation	activation	NN
cord-254419-qw83atrx	98	20	of	of	IN
cord-254419-qw83atrx	98	21	the	the	DT
cord-254419-qw83atrx	98	22	innate	innate	JJ
cord-254419-qw83atrx	98	23	immune	immune	JJ
cord-254419-qw83atrx	98	24	system	system	NN
cord-254419-qw83atrx	98	25	causes	cause	VBZ
cord-254419-qw83atrx	98	26	a	a	DT
cord-254419-qw83atrx	98	27	disease	disease	NN
cord-254419-qw83atrx	98	28	phenomenon	phenomenon	NN
cord-254419-qw83atrx	98	29	that	that	WDT
cord-254419-qw83atrx	98	30	is	be	VBZ
cord-254419-qw83atrx	98	31	similar	similar	JJ
cord-254419-qw83atrx	98	32	to	to	IN
cord-254419-qw83atrx	98	33	MAS	MAS	NNP
cord-254419-qw83atrx	98	34	/	/	SYM
cord-254419-qw83atrx	98	35	hemophagocytic	hemophagocytic	JJ
cord-254419-qw83atrx	98	36	lymphohistiocytosis	lymphohistiocytosis	NNP
cord-254419-qw83atrx	98	37	(	(	-LRB-
cord-254419-qw83atrx	98	38	HLH	HLH	NNP
cord-254419-qw83atrx	98	39	)	)	-RRB-
cord-254419-qw83atrx	98	40	.	.	.
cord-254419-qw83atrx	99	1	Comparing	compare	VBG
cord-254419-qw83atrx	99	2	the	the	DT
cord-254419-qw83atrx	99	3	laboratory	laboratory	NN
cord-254419-qw83atrx	99	4	features	feature	NNS
cord-254419-qw83atrx	99	5	,	,	,
cord-254419-qw83atrx	99	6	hyperferritinemia	hyperferritinemia	NN
cord-254419-qw83atrx	99	7	and	and	CC
cord-254419-qw83atrx	99	8	high	high	JJ
cord-254419-qw83atrx	99	9	lactate	lactate	NN
cord-254419-qw83atrx	99	10	dehydrogenase	dehydrogenase	NN
cord-254419-qw83atrx	99	11	(	(	-LRB-
cord-254419-qw83atrx	99	12	LDH	LDH	NNP
cord-254419-qw83atrx	99	13	)	)	-RRB-
cord-254419-qw83atrx	99	14	levels	level	NNS
cord-254419-qw83atrx	99	15	are	be	VBP
cord-254419-qw83atrx	99	16	common	common	JJ
cord-254419-qw83atrx	99	17	in	in	IN
cord-254419-qw83atrx	99	18	both	both	DT
cord-254419-qw83atrx	99	19	COVID-19	covid-19	JJ
cord-254419-qw83atrx	99	20	patients	patient	NNS
cord-254419-qw83atrx	99	21	and	and	CC
cord-254419-qw83atrx	99	22	patients	patient	NNS
cord-254419-qw83atrx	99	23	with	with	IN
cord-254419-qw83atrx	99	24	primary	primary	JJ
cord-254419-qw83atrx	99	25	HLH	HLH	NNP
cord-254419-qw83atrx	99	26	.	.	.
cord-254419-qw83atrx	100	1	On	on	IN
cord-254419-qw83atrx	100	2	the	the	DT
cord-254419-qw83atrx	100	3	other	other	JJ
cord-254419-qw83atrx	100	4	hand	hand	NN
cord-254419-qw83atrx	100	5	,	,	,
cord-254419-qw83atrx	100	6	low	low	JJ
cord-254419-qw83atrx	100	7	fibrinogen	fibrinogen	NN
cord-254419-qw83atrx	100	8	and	and	CC
cord-254419-qw83atrx	100	9	cytopenias	cytopenia	NNS
cord-254419-qw83atrx	100	10	due	due	IN
cord-254419-qw83atrx	100	11	to	to	IN
cord-254419-qw83atrx	100	12	bone	bone	NN
cord-254419-qw83atrx	100	13	marrow	marrow	NN
cord-254419-qw83atrx	100	14	hemophagocytosis	hemophagocytosis	NN
cord-254419-qw83atrx	100	15	is	be	VBZ
cord-254419-qw83atrx	100	16	not	not	RB
cord-254419-qw83atrx	100	17	commonly	commonly	RB
cord-254419-qw83atrx	100	18	found	find	VBN
cord-254419-qw83atrx	100	19	in	in	IN
cord-254419-qw83atrx	100	20	COVID-19	covid-19	CD
cord-254419-qw83atrx	100	21	patients	patient	NNS
cord-254419-qw83atrx	100	22	[	[	-LRB-
cord-254419-qw83atrx	100	23	28	28	CD
cord-254419-qw83atrx	100	24	]	]	-RRB-
cord-254419-qw83atrx	100	25	.	.	.
cord-254419-qw83atrx	101	1	It	-PRON-	PRP
cord-254419-qw83atrx	101	2	is	be	VBZ
cord-254419-qw83atrx	101	3	likely	likely	JJ
cord-254419-qw83atrx	101	4	that	that	IN
cord-254419-qw83atrx	101	5	the	the	DT
cord-254419-qw83atrx	101	6	pathophysiology	pathophysiology	NN
cord-254419-qw83atrx	101	7	of	of	IN
cord-254419-qw83atrx	101	8	COVID-19	covid-19	JJ
cord-254419-qw83atrx	101	9	overlaps	overlap	NNS
cord-254419-qw83atrx	101	10	with	with	IN
cord-254419-qw83atrx	101	11	low	low	JJ
cord-254419-qw83atrx	101	12	-	-	HYPH
cord-254419-qw83atrx	101	13	grade	grade	NN
cord-254419-qw83atrx	101	14	HLH	HLH	NNP
cord-254419-qw83atrx	101	15	,	,	,
cord-254419-qw83atrx	101	16	and	and	CC
cord-254419-qw83atrx	101	17	further	further	JJ
cord-254419-qw83atrx	101	18	studies	study	NNS
cord-254419-qw83atrx	101	19	addressing	address	VBG
cord-254419-qw83atrx	101	20	this	this	DT
cord-254419-qw83atrx	101	21	aspect	aspect	NN
cord-254419-qw83atrx	101	22	will	will	MD
cord-254419-qw83atrx	101	23	be	be	VB
cord-254419-qw83atrx	101	24	important	important	JJ
cord-254419-qw83atrx	101	25	to	to	TO
cord-254419-qw83atrx	101	26	evaluate	evaluate	VB
cord-254419-qw83atrx	101	27	the	the	DT
cord-254419-qw83atrx	101	28	role	role	NN
cord-254419-qw83atrx	101	29	of	of	IN
cord-254419-qw83atrx	101	30	immunosuppression	immunosuppression	NN
cord-254419-qw83atrx	101	31	and	and	CC
cord-254419-qw83atrx	101	32	HLH	HLH	NNP
cord-254419-qw83atrx	101	33	type	type	NN
cord-254419-qw83atrx	101	34	therapy	therapy	NN
cord-254419-qw83atrx	101	35	in	in	IN
cord-254419-qw83atrx	101	36	these	these	DT
cord-254419-qw83atrx	101	37	patients	patient	NNS
cord-254419-qw83atrx	101	38	.	.	.
cord-254419-qw83atrx	102	1	The	the	DT
cord-254419-qw83atrx	102	2	acronym	acronym	NN
cord-254419-qw83atrx	102	3	COVID-19-associated	covid-19-associated	JJ
cord-254419-qw83atrx	102	4	coagulopathy	coagulopathy	NN
cord-254419-qw83atrx	102	5	(	(	-LRB-
cord-254419-qw83atrx	102	6	CAC	CAC	NNP
cord-254419-qw83atrx	102	7	)	)	-RRB-
cord-254419-qw83atrx	102	8	is	be	VBZ
cord-254419-qw83atrx	102	9	being	be	VBG
cord-254419-qw83atrx	102	10	used	use	VBN
cord-254419-qw83atrx	102	11	to	to	TO
cord-254419-qw83atrx	102	12	describe	describe	VB
cord-254419-qw83atrx	102	13	the	the	DT
cord-254419-qw83atrx	102	14	coagulation	coagulation	NN
cord-254419-qw83atrx	102	15	changes	change	NNS
cord-254419-qw83atrx	102	16	in	in	IN
cord-254419-qw83atrx	102	17	infected	infected	JJ
cord-254419-qw83atrx	102	18	patients	patient	NNS
cord-254419-qw83atrx	102	19	[	[	-LRB-
cord-254419-qw83atrx	102	20	29	29	CD
cord-254419-qw83atrx	102	21	]	]	-RRB-
cord-254419-qw83atrx	102	22	.	.	.
cord-254419-qw83atrx	103	1	Abnormal	abnormal	JJ
cord-254419-qw83atrx	103	2	coagulation	coagulation	NN
cord-254419-qw83atrx	103	3	parameters	parameter	NNS
cord-254419-qw83atrx	103	4	including	include	VBG
cord-254419-qw83atrx	103	5	increased	increase	VBN
cord-254419-qw83atrx	103	6	D	d	NN
cord-254419-qw83atrx	103	7	-	-	HYPH
cord-254419-qw83atrx	103	8	dimer	dimer	NN
cord-254419-qw83atrx	103	9	,	,	,
cord-254419-qw83atrx	103	10	fibrin	fibrin	NN
cord-254419-qw83atrx	103	11	degradation	degradation	NN
cord-254419-qw83atrx	103	12	products	product	NNS
cord-254419-qw83atrx	103	13	,	,	,
cord-254419-qw83atrx	103	14	and	and	CC
cord-254419-qw83atrx	103	15	prolonged	prolong	VBN
cord-254419-qw83atrx	103	16	pro	pro	JJ
cord-254419-qw83atrx	103	17	-	-	JJ
cord-254419-qw83atrx	103	18	thrombin	thrombin	JJ
cord-254419-qw83atrx	103	19	time	time	NN
cord-254419-qw83atrx	103	20	have	have	VBP
cord-254419-qw83atrx	103	21	been	be	VBN
cord-254419-qw83atrx	103	22	found	find	VBN
cord-254419-qw83atrx	103	23	to	to	TO
cord-254419-qw83atrx	103	24	be	be	VB
cord-254419-qw83atrx	103	25	associated	associate	VBN
cord-254419-qw83atrx	103	26	with	with	IN
cord-254419-qw83atrx	103	27	poor	poor	JJ
cord-254419-qw83atrx	103	28	prognosis	prognosis	NN
cord-254419-qw83atrx	103	29	[	[	-LRB-
cord-254419-qw83atrx	103	30	30	30	CD
cord-254419-qw83atrx	103	31	]	]	-RRB-
cord-254419-qw83atrx	103	32	.	.	.
cord-254419-qw83atrx	104	1	In	in	IN
cord-254419-qw83atrx	104	2	a	a	DT
cord-254419-qw83atrx	104	3	study	study	NN
cord-254419-qw83atrx	104	4	of	of	IN
cord-254419-qw83atrx	104	5	183	183	CD
cord-254419-qw83atrx	104	6	patients	patient	NNS
cord-254419-qw83atrx	104	7	with	with	IN
cord-254419-qw83atrx	104	8	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	104	9	disease	disease	NN
cord-254419-qw83atrx	104	10	,	,	,
cord-254419-qw83atrx	104	11	15	15	CD
cord-254419-qw83atrx	104	12	out	out	IN
cord-254419-qw83atrx	104	13	of	of	IN
cord-254419-qw83atrx	104	14	21	21	CD
cord-254419-qw83atrx	104	15	(	(	-LRB-
cord-254419-qw83atrx	104	16	71.4	71.4	CD
cord-254419-qw83atrx	104	17	%	%	NN
cord-254419-qw83atrx	104	18	)	)	-RRB-
cord-254419-qw83atrx	104	19	non	non	NNS
cord-254419-qw83atrx	104	20	-	-	NNS
cord-254419-qw83atrx	104	21	survivors	survivor	NNS
cord-254419-qw83atrx	104	22	had	have	VBD
cord-254419-qw83atrx	104	23	disseminated	disseminate	VBN
cord-254419-qw83atrx	104	24	intravascular	intravascular	JJ
cord-254419-qw83atrx	104	25	coagulation	coagulation	NN
cord-254419-qw83atrx	104	26	(	(	-LRB-
cord-254419-qw83atrx	104	27	DIC	DIC	NNP
cord-254419-qw83atrx	104	28	)	)	-RRB-
cord-254419-qw83atrx	104	29	as	as	IN
cord-254419-qw83atrx	104	30	per	per	IN
cord-254419-qw83atrx	104	31	the	the	DT
cord-254419-qw83atrx	104	32	criteria	criterion	NNS
cord-254419-qw83atrx	104	33	set	set	VBN
cord-254419-qw83atrx	104	34	by	by	IN
cord-254419-qw83atrx	104	35	the	the	DT
cord-254419-qw83atrx	104	36	International	International	NNP
cord-254419-qw83atrx	104	37	Society	Society	NNP
cord-254419-qw83atrx	104	38	of	of	IN
cord-254419-qw83atrx	104	39	Thrombosis	Thrombosis	NNP
cord-254419-qw83atrx	104	40	and	and	CC
cord-254419-qw83atrx	104	41	Haemostasis	Haemostasis	NNP
cord-254419-qw83atrx	104	42	(	(	-LRB-
cord-254419-qw83atrx	104	43	ISTH	ISTH	NNP
cord-254419-qw83atrx	104	44	)	)	-RRB-
cord-254419-qw83atrx	104	45	.	.	.
cord-254419-qw83atrx	105	1	This	this	DT
cord-254419-qw83atrx	105	2	was	be	VBD
cord-254419-qw83atrx	105	3	in	in	IN
cord-254419-qw83atrx	105	4	contrast	contrast	NN
cord-254419-qw83atrx	105	5	to	to	IN
cord-254419-qw83atrx	105	6	only	only	RB
cord-254419-qw83atrx	105	7	one	one	CD
cord-254419-qw83atrx	105	8	(	(	-LRB-
cord-254419-qw83atrx	105	9	0.6	0.6	CD
cord-254419-qw83atrx	105	10	%	%	NN
cord-254419-qw83atrx	105	11	)	)	-RRB-
cord-254419-qw83atrx	105	12	survivor	survivor	NN
cord-254419-qw83atrx	105	13	fulfilling	fulfil	VBG
cord-254419-qw83atrx	105	14	the	the	DT
cord-254419-qw83atrx	105	15	criteria	criterion	NNS
cord-254419-qw83atrx	105	16	for	for	IN
cord-254419-qw83atrx	105	17	DIC	DIC	NNP
cord-254419-qw83atrx	105	18	during	during	IN
cord-254419-qw83atrx	105	19	the	the	DT
cord-254419-qw83atrx	105	20	period	period	NN
cord-254419-qw83atrx	105	21	of	of	IN
cord-254419-qw83atrx	105	22	hospitalization	hospitalization	NN
cord-254419-qw83atrx	105	23	,	,	,
cord-254419-qw83atrx	105	24	indicating	indicate	VBG
cord-254419-qw83atrx	105	25	that	that	IN
cord-254419-qw83atrx	105	26	non	non	NNS
cord-254419-qw83atrx	105	27	-	-	NNS
cord-254419-qw83atrx	105	28	survivors	survivor	NNS
cord-254419-qw83atrx	105	29	have	have	VBP
cord-254419-qw83atrx	105	30	a	a	DT
cord-254419-qw83atrx	105	31	higher	high	JJR
cord-254419-qw83atrx	105	32	incidence	incidence	NN
cord-254419-qw83atrx	105	33	of	of	IN
cord-254419-qw83atrx	105	34	DIC	DIC	NNP
cord-254419-qw83atrx	105	35	.	.	.
cord-254419-qw83atrx	106	1	Described	describe	VBN
cord-254419-qw83atrx	106	2	incidence	incidence	NN
cord-254419-qw83atrx	106	3	of	of	IN
cord-254419-qw83atrx	106	4	thrombocytopenia	thrombocytopenia	NN
cord-254419-qw83atrx	106	5	has	have	VBZ
cord-254419-qw83atrx	106	6	been	be	VBN
cord-254419-qw83atrx	106	7	variable	variable	JJ
cord-254419-qw83atrx	106	8	,	,	,
cord-254419-qw83atrx	106	9	reported	report	VBN
cord-254419-qw83atrx	106	10	as	as	IN
cord-254419-qw83atrx	106	11	12	12	CD
cord-254419-qw83atrx	106	12	%	%	NN
cord-254419-qw83atrx	106	13	in	in	IN
cord-254419-qw83atrx	106	14	an	an	DT
cord-254419-qw83atrx	106	15	initial	initial	JJ
cord-254419-qw83atrx	106	16	case	case	NN
cord-254419-qw83atrx	106	17	series	series	NN
cord-254419-qw83atrx	106	18	of	of	IN
cord-254419-qw83atrx	106	19	99	99	CD
cord-254419-qw83atrx	106	20	patients	patient	NNS
cord-254419-qw83atrx	106	21	[	[	-LRB-
cord-254419-qw83atrx	106	22	31	31	CD
cord-254419-qw83atrx	106	23	]	]	-RRB-
cord-254419-qw83atrx	106	24	and	and	CC
cord-254419-qw83atrx	106	25	36.2	36.2	CD
cord-254419-qw83atrx	106	26	%	%	NN
cord-254419-qw83atrx	106	27	in	in	IN
cord-254419-qw83atrx	106	28	another	another	DT
cord-254419-qw83atrx	106	29	series	series	NN
cord-254419-qw83atrx	106	30	of	of	IN
cord-254419-qw83atrx	106	31	1099	1099	CD
cord-254419-qw83atrx	106	32	patients	patient	NNS
cord-254419-qw83atrx	106	33	[	[	-LRB-
cord-254419-qw83atrx	106	34	32	32	CD
cord-254419-qw83atrx	106	35	]	]	-RRB-
cord-254419-qw83atrx	106	36	.	.	.
cord-254419-qw83atrx	107	1	A	a	DT
cord-254419-qw83atrx	107	2	meta	meta	JJ
cord-254419-qw83atrx	107	3	-	-	HYPH
cord-254419-qw83atrx	107	4	analysis	analysis	NN
cord-254419-qw83atrx	107	5	analyzing	analyze	VBG
cord-254419-qw83atrx	107	6	pooled	pool	VBN
cord-254419-qw83atrx	107	7	data	datum	NNS
cord-254419-qw83atrx	107	8	from	from	IN
cord-254419-qw83atrx	107	9	nine	nine	CD
cord-254419-qw83atrx	107	10	studies	study	NNS
cord-254419-qw83atrx	107	11	of	of	IN
cord-254419-qw83atrx	107	12	1779	1779	CD
cord-254419-qw83atrx	107	13	patients	patient	NNS
cord-254419-qw83atrx	107	14	including	include	VBG
cord-254419-qw83atrx	107	15	399	399	CD
cord-254419-qw83atrx	107	16	with	with	IN
cord-254419-qw83atrx	107	17	severe	severe	JJ
cord-254419-qw83atrx	107	18	disease	disease	NN
cord-254419-qw83atrx	107	19	has	have	VBZ
cord-254419-qw83atrx	107	20	demonstrated	demonstrate	VBN
cord-254419-qw83atrx	107	21	that	that	IN
cord-254419-qw83atrx	107	22	thrombocytopenia	thrombocytopenia	NN
cord-254419-qw83atrx	107	23	is	be	VBZ
cord-254419-qw83atrx	107	24	prognostic	prognostic	JJ
cord-254419-qw83atrx	107	25	of	of	IN
cord-254419-qw83atrx	107	26	the	the	DT
cord-254419-qw83atrx	107	27	severity	severity	NN
cord-254419-qw83atrx	107	28	of	of	IN
cord-254419-qw83atrx	107	29	the	the	DT
cord-254419-qw83atrx	107	30	disease	disease	NN
cord-254419-qw83atrx	107	31	.	.	.
cord-254419-qw83atrx	108	1	Although	although	IN
cord-254419-qw83atrx	108	2	there	there	EX
cord-254419-qw83atrx	108	3	was	be	VBD
cord-254419-qw83atrx	108	4	notable	notable	JJ
cord-254419-qw83atrx	108	5	heterogeneity	heterogeneity	NN
cord-254419-qw83atrx	108	6	between	between	IN
cord-254419-qw83atrx	108	7	studies	study	NNS
cord-254419-qw83atrx	108	8	,	,	,
cord-254419-qw83atrx	108	9	severe	severe	JJ
cord-254419-qw83atrx	108	10	thrombocytopenia	thrombocytopenia	NN
cord-254419-qw83atrx	108	11	was	be	VBD
cord-254419-qw83atrx	108	12	common	common	JJ
cord-254419-qw83atrx	108	13	in	in	IN
cord-254419-qw83atrx	108	14	non	non	NNS
cord-254419-qw83atrx	108	15	-	-	NNS
cord-254419-qw83atrx	108	16	survivors	survivor	NNS
cord-254419-qw83atrx	108	17	[	[	-LRB-
cord-254419-qw83atrx	108	18	33	33	CD
cord-254419-qw83atrx	108	19	]	]	-RRB-
cord-254419-qw83atrx	108	20	and	and	CC
cord-254419-qw83atrx	108	21	increased	increase	VBN
cord-254419-qw83atrx	108	22	mortality	mortality	NN
cord-254419-qw83atrx	108	23	has	have	VBZ
cord-254419-qw83atrx	108	24	been	be	VBN
cord-254419-qw83atrx	108	25	associated	associate	VBN
cord-254419-qw83atrx	108	26	with	with	IN
cord-254419-qw83atrx	108	27	lower	low	JJR
cord-254419-qw83atrx	108	28	platelet	platelet	NN
cord-254419-qw83atrx	108	29	counts	count	NNS
cord-254419-qw83atrx	108	30	[	[	-LRB-
cord-254419-qw83atrx	108	31	34	34	CD
cord-254419-qw83atrx	108	32	]	]	-RRB-
cord-254419-qw83atrx	108	33	.	.	.
cord-254419-qw83atrx	109	1	Activated	activate	VBN
cord-254419-qw83atrx	109	2	partial	partial	JJ
cord-254419-qw83atrx	109	3	thromboplastin	thromboplastin	NNP
cord-254419-qw83atrx	109	4	time	time	NN
cord-254419-qw83atrx	109	5	(	(	-LRB-
cord-254419-qw83atrx	109	6	aPTT)based	aptt)based	JJ
cord-254419-qw83atrx	109	7	clot	clot	NN
cord-254419-qw83atrx	109	8	waveform	waveform	NN
cord-254419-qw83atrx	109	9	analysis	analysis	NN
cord-254419-qw83atrx	109	10	(	(	-LRB-
cord-254419-qw83atrx	109	11	CWA	CWA	NNP
cord-254419-qw83atrx	109	12	)	)	-RRB-
cord-254419-qw83atrx	109	13	is	be	VBZ
cord-254419-qw83atrx	109	14	an	an	DT
cord-254419-qw83atrx	109	15	easily	easily	RB
cord-254419-qw83atrx	109	16	available	available	JJ
cord-254419-qw83atrx	109	17	form	form	NN
cord-254419-qw83atrx	109	18	of	of	IN
cord-254419-qw83atrx	109	19	global	global	JJ
cord-254419-qw83atrx	109	20	hemostatic	hemostatic	JJ
cord-254419-qw83atrx	109	21	assay	assay	NN
cord-254419-qw83atrx	109	22	and	and	CC
cord-254419-qw83atrx	109	23	remarkably	remarkably	RB
cord-254419-qw83atrx	109	24	high	high	JJ
cord-254419-qw83atrx	109	25	CWA	CWA	NNP
cord-254419-qw83atrx	109	26	were	be	VBD
cord-254419-qw83atrx	109	27	noted	note	VBN
cord-254419-qw83atrx	109	28	despite	despite	IN
cord-254419-qw83atrx	109	29	prophylactic	prophylactic	JJ
cord-254419-qw83atrx	109	30	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	109	31	in	in	IN
cord-254419-qw83atrx	109	32	patients	patient	NNS
cord-254419-qw83atrx	109	33	admitted	admit	VBN
cord-254419-qw83atrx	109	34	to	to	IN
cord-254419-qw83atrx	109	35	the	the	DT
cord-254419-qw83atrx	109	36	ICU	ICU	NNP
cord-254419-qw83atrx	109	37	although	although	IN
cord-254419-qw83atrx	109	38	there	there	EX
cord-254419-qw83atrx	109	39	was	be	VBD
cord-254419-qw83atrx	109	40	no	no	DT
cord-254419-qw83atrx	109	41	thrombosis	thrombosis	NN
cord-254419-qw83atrx	109	42	or	or	CC
cord-254419-qw83atrx	109	43	death	death	NN
cord-254419-qw83atrx	109	44	in	in	IN
cord-254419-qw83atrx	109	45	a	a	DT
cord-254419-qw83atrx	109	46	study	study	NN
cord-254419-qw83atrx	109	47	from	from	IN
cord-254419-qw83atrx	109	48	Singapore	Singapore	NNP
cord-254419-qw83atrx	109	49	[	[	-LRB-
cord-254419-qw83atrx	109	50	35	35	CD
cord-254419-qw83atrx	109	51	]	]	-RRB-
cord-254419-qw83atrx	109	52	.	.	.
cord-254419-qw83atrx	110	1	A	a	DT
cord-254419-qw83atrx	110	2	study	study	NN
cord-254419-qw83atrx	110	3	on	on	IN
cord-254419-qw83atrx	110	4	24	24	CD
cord-254419-qw83atrx	110	5	critically	critically	RB
cord-254419-qw83atrx	110	6	ill	ill	JJ
cord-254419-qw83atrx	110	7	patients	patient	NNS
cord-254419-qw83atrx	110	8	analyzed	analyze	VBD
cord-254419-qw83atrx	110	9	whole	whole	JJ
cord-254419-qw83atrx	110	10	-	-	HYPH
cord-254419-qw83atrx	110	11	blood	blood	NN
cord-254419-qw83atrx	110	12	thromboelastography	thromboelastography	NN
cord-254419-qw83atrx	110	13	(	(	-LRB-
cord-254419-qw83atrx	110	14	TEG	TEG	NNP
cord-254419-qw83atrx	110	15	)	)	-RRB-
cord-254419-qw83atrx	110	16	which	which	WDT
cord-254419-qw83atrx	110	17	showed	show	VBD
cord-254419-qw83atrx	110	18	decreased	decrease	VBN
cord-254419-qw83atrx	110	19	R	r	NN
cord-254419-qw83atrx	110	20	(	(	-LRB-
cord-254419-qw83atrx	110	21	reaction	reaction	NN
cord-254419-qw83atrx	110	22	time	time	NN
cord-254419-qw83atrx	110	23	)	)	-RRB-
cord-254419-qw83atrx	110	24	and	and	CC
cord-254419-qw83atrx	110	25	K	K	NNP
cord-254419-qw83atrx	110	26	(	(	-LRB-
cord-254419-qw83atrx	110	27	kinetics	kinetics	NNP
cord-254419-qw83atrx	110	28	time	time	NN
cord-254419-qw83atrx	110	29	)	)	-RRB-
cord-254419-qw83atrx	110	30	values	value	NNS
cord-254419-qw83atrx	110	31	but	but	CC
cord-254419-qw83atrx	110	32	increased	increase	VBD
cord-254419-qw83atrx	110	33	K	k	NN
cord-254419-qw83atrx	110	34	angle	angle	NN
cord-254419-qw83atrx	110	35	and	and	CC
cord-254419-qw83atrx	110	36	MA	MA	NNP
cord-254419-qw83atrx	110	37	(	(	-LRB-
cord-254419-qw83atrx	110	38	maximum	maximum	JJ
cord-254419-qw83atrx	110	39	amplitude	amplitude	NN
cord-254419-qw83atrx	110	40	)	)	-RRB-
cord-254419-qw83atrx	110	41	values	value	NNS
cord-254419-qw83atrx	110	42	,	,	,
cord-254419-qw83atrx	110	43	which	which	WDT
cord-254419-qw83atrx	110	44	is	be	VBZ
cord-254419-qw83atrx	110	45	consistent	consistent	JJ
cord-254419-qw83atrx	110	46	with	with	IN
cord-254419-qw83atrx	110	47	hypercoagulability	hypercoagulability	NN
cord-254419-qw83atrx	110	48	.	.	.
cord-254419-qw83atrx	111	1	Factor	factor	NN
cord-254419-qw83atrx	111	2	VIII	VIII	NNP
cord-254419-qw83atrx	111	3	,	,	,
cord-254419-qw83atrx	111	4	Von	Von	NNP
cord-254419-qw83atrx	111	5	Willebrand	Willebrand	NNP
cord-254419-qw83atrx	111	6	factor	factor	NN
cord-254419-qw83atrx	111	7	,	,	,
cord-254419-qw83atrx	111	8	fibrinogen	fibrinogen	NN
cord-254419-qw83atrx	111	9	,	,	,
cord-254419-qw83atrx	111	10	D	d	NN
cord-254419-qw83atrx	111	11	-	-	HYPH
cord-254419-qw83atrx	111	12	dimer	dimer	NN
cord-254419-qw83atrx	111	13	,	,	,
cord-254419-qw83atrx	111	14	platelets	platelet	NNS
cord-254419-qw83atrx	111	15	,	,	,
cord-254419-qw83atrx	111	16	and	and	CC
cord-254419-qw83atrx	111	17	protein	protein	NN
cord-254419-qw83atrx	111	18	C	C	NNP
cord-254419-qw83atrx	111	19	were	be	VBD
cord-254419-qw83atrx	111	20	increased	increase	VBN
cord-254419-qw83atrx	111	21	in	in	IN
cord-254419-qw83atrx	111	22	most	most	JJS
cord-254419-qw83atrx	111	23	patients	patient	NNS
cord-254419-qw83atrx	111	24	,	,	,
cord-254419-qw83atrx	111	25	and	and	CC
cord-254419-qw83atrx	111	26	antithrombin	antithrombin	NN
cord-254419-qw83atrx	111	27	marginally	marginally	RB
cord-254419-qw83atrx	111	28	decreased	decrease	VBD
cord-254419-qw83atrx	111	29	,	,	,
cord-254419-qw83atrx	111	30	while	while	IN
cord-254419-qw83atrx	111	31	prothrombin	prothrombin	JJ
cord-254419-qw83atrx	111	32	time	time	NN
cord-254419-qw83atrx	111	33	(	(	-LRB-
cord-254419-qw83atrx	111	34	PT	PT	NNP
cord-254419-qw83atrx	111	35	)	)	-RRB-
cord-254419-qw83atrx	111	36	and	and	CC
cord-254419-qw83atrx	111	37	APTT	APTT	NNP
cord-254419-qw83atrx	111	38	were	be	VBD
cord-254419-qw83atrx	111	39	mostly	mostly	RB
cord-254419-qw83atrx	111	40	normal	normal	JJ
cord-254419-qw83atrx	111	41	[	[	-LRB-
cord-254419-qw83atrx	111	42	36	36	CD
cord-254419-qw83atrx	111	43	]	]	-RRB-
cord-254419-qw83atrx	111	44	.	.	.
cord-254419-qw83atrx	112	1	The	the	DT
cord-254419-qw83atrx	112	2	authors	author	NNS
cord-254419-qw83atrx	112	3	concluded	conclude	VBD
cord-254419-qw83atrx	112	4	that	that	IN
cord-254419-qw83atrx	112	5	the	the	DT
cord-254419-qw83atrx	112	6	above	above	JJ
cord-254419-qw83atrx	112	7	findings	finding	NNS
cord-254419-qw83atrx	112	8	do	do	VBP
cord-254419-qw83atrx	112	9	not	not	RB
cord-254419-qw83atrx	112	10	support	support	VB
cord-254419-qw83atrx	112	11	features	feature	NNS
cord-254419-qw83atrx	112	12	of	of	IN
cord-254419-qw83atrx	112	13	acute	acute	JJ
cord-254419-qw83atrx	112	14	DIC	DIC	NNP
cord-254419-qw83atrx	112	15	but	but	CC
cord-254419-qw83atrx	112	16	are	be	VBP
cord-254419-qw83atrx	112	17	consistent	consistent	JJ
cord-254419-qw83atrx	112	18	with	with	IN
cord-254419-qw83atrx	112	19	severe	severe	JJ
cord-254419-qw83atrx	112	20	hypercoagulability	hypercoagulability	NN
cord-254419-qw83atrx	112	21	secondary	secondary	JJ
cord-254419-qw83atrx	112	22	to	to	IN
cord-254419-qw83atrx	112	23	inflammation	inflammation	NN
cord-254419-qw83atrx	112	24	.	.	.
cord-254419-qw83atrx	113	1	Another	another	DT
cord-254419-qw83atrx	113	2	similar	similar	JJ
cord-254419-qw83atrx	113	3	study	study	NN
cord-254419-qw83atrx	113	4	in	in	IN
cord-254419-qw83atrx	113	5	44	44	CD
cord-254419-qw83atrx	113	6	patients	patient	NNS
cord-254419-qw83atrx	113	7	admitted	admit	VBN
cord-254419-qw83atrx	113	8	to	to	IN
cord-254419-qw83atrx	113	9	the	the	DT
cord-254419-qw83atrx	113	10	ICU	ICU	NNP
cord-254419-qw83atrx	113	11	with	with	IN
cord-254419-qw83atrx	113	12	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	113	13	showed	show	VBD
cord-254419-qw83atrx	113	14	fibrinolysis	fibrinolysis	NN
cord-254419-qw83atrx	113	15	shutdown	shutdown	NN
cord-254419-qw83atrx	113	16	as	as	IN
cord-254419-qw83atrx	113	17	evidenced	evidence	VBN
cord-254419-qw83atrx	113	18	by	by	IN
cord-254419-qw83atrx	113	19	markedly	markedly	RB
cord-254419-qw83atrx	113	20	raised	raise	VBN
cord-254419-qw83atrx	113	21	D	d	NN
cord-254419-qw83atrx	113	22	-	-	HYPH
cord-254419-qw83atrx	113	23	dimer	dimer	NN
cord-254419-qw83atrx	113	24	and	and	CC
cord-254419-qw83atrx	113	25	complete	complete	JJ
cord-254419-qw83atrx	113	26	absence	absence	NN
cord-254419-qw83atrx	113	27	of	of	IN
cord-254419-qw83atrx	113	28	clot	clot	NN
cord-254419-qw83atrx	113	29	lysis	lysis	NN
cord-254419-qw83atrx	113	30	in	in	IN
cord-254419-qw83atrx	113	31	TEG	TEG	NNP
cord-254419-qw83atrx	113	32	at	at	IN
cord-254419-qw83atrx	113	33	30	30	CD
cord-254419-qw83atrx	113	34	min	min	NN
cord-254419-qw83atrx	113	35	;	;	:
cord-254419-qw83atrx	113	36	this	this	DT
cord-254419-qw83atrx	113	37	was	be	VBD
cord-254419-qw83atrx	113	38	predictive	predictive	JJ
cord-254419-qw83atrx	113	39	of	of	IN
cord-254419-qw83atrx	113	40	high	high	JJ
cord-254419-qw83atrx	113	41	rate	rate	NN
cord-254419-qw83atrx	113	42	of	of	IN
cord-254419-qw83atrx	113	43	venous	venous	JJ
cord-254419-qw83atrx	113	44	thrombosis	thrombosis	NN
cord-254419-qw83atrx	113	45	)	)	-RRB-
cord-254419-qw83atrx	113	46	and	and	CC
cord-254419-qw83atrx	113	47	need	need	VBP
cord-254419-qw83atrx	113	48	for	for	IN
cord-254419-qw83atrx	113	49	hemodialysis	hemodialysis	NN
cord-254419-qw83atrx	113	50	[	[	-LRB-
cord-254419-qw83atrx	113	51	37	37	CD
cord-254419-qw83atrx	113	52	]	]	-RRB-
cord-254419-qw83atrx	113	53	.	.	.
cord-254419-qw83atrx	114	1	This	this	DT
cord-254419-qw83atrx	114	2	may	may	MD
cord-254419-qw83atrx	114	3	suggest	suggest	VB
cord-254419-qw83atrx	114	4	that	that	IN
cord-254419-qw83atrx	114	5	functional	functional	JJ
cord-254419-qw83atrx	114	6	coagulation	coagulation	NN
cord-254419-qw83atrx	114	7	assessment	assessment	NN
cord-254419-qw83atrx	114	8	like	like	IN
cord-254419-qw83atrx	114	9	TEG	TEG	NNP
cord-254419-qw83atrx	114	10	may	may	MD
cord-254419-qw83atrx	114	11	be	be	VB
cord-254419-qw83atrx	114	12	more	more	RBR
cord-254419-qw83atrx	114	13	useful	useful	JJ
cord-254419-qw83atrx	114	14	in	in	IN
cord-254419-qw83atrx	114	15	assessing	assess	VBG
cord-254419-qw83atrx	114	16	hypercoagulability	hypercoagulability	NN
cord-254419-qw83atrx	114	17	rather	rather	RB
cord-254419-qw83atrx	114	18	than	than	IN
cord-254419-qw83atrx	114	19	conventional	conventional	JJ
cord-254419-qw83atrx	114	20	coagulation	coagulation	NN
cord-254419-qw83atrx	114	21	tests	test	NNS
cord-254419-qw83atrx	114	22	in	in	IN
cord-254419-qw83atrx	114	23	patients	patient	NNS
cord-254419-qw83atrx	114	24	with	with	IN
cord-254419-qw83atrx	114	25	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	114	26	.	.	.
cord-254419-qw83atrx	115	1	A	a	DT
cord-254419-qw83atrx	115	2	high	high	JJ
cord-254419-qw83atrx	115	3	rate	rate	NN
cord-254419-qw83atrx	115	4	of	of	IN
cord-254419-qw83atrx	115	5	venous	venous	JJ
cord-254419-qw83atrx	115	6	thrombosis	thrombosis	NN
cord-254419-qw83atrx	115	7	has	have	VBZ
cord-254419-qw83atrx	115	8	been	be	VBN
cord-254419-qw83atrx	115	9	observed	observe	VBN
cord-254419-qw83atrx	115	10	even	even	RB
cord-254419-qw83atrx	115	11	in	in	IN
cord-254419-qw83atrx	115	12	anti	anti	JJ
cord-254419-qw83atrx	115	13	-	-	JJ
cord-254419-qw83atrx	115	14	coagulated	coagulated	JJ
cord-254419-qw83atrx	115	15	patients	patient	NNS
cord-254419-qw83atrx	115	16	with	with	IN
cord-254419-qw83atrx	115	17	this	this	DT
cord-254419-qw83atrx	115	18	disease	disease	NN
cord-254419-qw83atrx	115	19	.	.	.
cord-254419-qw83atrx	116	1	In	in	IN
cord-254419-qw83atrx	116	2	a	a	DT
cord-254419-qw83atrx	116	3	French	french	JJ
cord-254419-qw83atrx	116	4	study	study	NN
cord-254419-qw83atrx	116	5	of	of	IN
cord-254419-qw83atrx	116	6	26	26	CD
cord-254419-qw83atrx	116	7	patients	patient	NNS
cord-254419-qw83atrx	116	8	on	on	IN
cord-254419-qw83atrx	116	9	mechanical	mechanical	JJ
cord-254419-qw83atrx	116	10	ventilation	ventilation	NN
cord-254419-qw83atrx	116	11	,	,	,
cord-254419-qw83atrx	116	12	prophylactic	prophylactic	JJ
cord-254419-qw83atrx	116	13	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	116	14	was	be	VBD
cord-254419-qw83atrx	116	15	used	use	VBN
cord-254419-qw83atrx	116	16	in	in	IN
cord-254419-qw83atrx	116	17	eight	eight	CD
cord-254419-qw83atrx	116	18	(	(	-LRB-
cord-254419-qw83atrx	116	19	31	31	CD
cord-254419-qw83atrx	116	20	%	%	NN
cord-254419-qw83atrx	116	21	)	)	-RRB-
cord-254419-qw83atrx	116	22	cases	case	NNS
cord-254419-qw83atrx	116	23	while	while	IN
cord-254419-qw83atrx	116	24	therapeutic	therapeutic	JJ
cord-254419-qw83atrx	116	25	dose	dose	NN
cord-254419-qw83atrx	116	26	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	116	27	with	with	IN
cord-254419-qw83atrx	116	28	low	low	JJ
cord-254419-qw83atrx	116	29	molecular	molecular	JJ
cord-254419-qw83atrx	116	30	weight	weight	NN
cord-254419-qw83atrx	116	31	heparin	heparin	NN
cord-254419-qw83atrx	116	32	(	(	-LRB-
cord-254419-qw83atrx	116	33	LMWH	LMWH	NNP
cord-254419-qw83atrx	116	34	)	)	-RRB-
cord-254419-qw83atrx	116	35	was	be	VBD
cord-254419-qw83atrx	116	36	started	start	VBN
cord-254419-qw83atrx	116	37	on	on	IN
cord-254419-qw83atrx	116	38	admission	admission	NN
cord-254419-qw83atrx	116	39	in	in	IN
cord-254419-qw83atrx	116	40	18	18	CD
cord-254419-qw83atrx	116	41	(	(	-LRB-
cord-254419-qw83atrx	116	42	69	69	CD
cord-254419-qw83atrx	116	43	%	%	NN
cord-254419-qw83atrx	116	44	)	)	-RRB-
cord-254419-qw83atrx	116	45	patients	patient	NNS
cord-254419-qw83atrx	116	46	[	[	-LRB-
cord-254419-qw83atrx	116	47	38	38	CD
cord-254419-qw83atrx	116	48	]	]	-RRB-
cord-254419-qw83atrx	116	49	.	.	.
cord-254419-qw83atrx	117	1	All	all	DT
cord-254419-qw83atrx	117	2	of	of	IN
cord-254419-qw83atrx	117	3	these	these	DT
cord-254419-qw83atrx	117	4	patients	patient	NNS
cord-254419-qw83atrx	117	5	were	be	VBD
cord-254419-qw83atrx	117	6	screened	screen	VBN
cord-254419-qw83atrx	117	7	by	by	IN
cord-254419-qw83atrx	117	8	Doppler	Doppler	NNP
cord-254419-qw83atrx	117	9	ultrasound	ultrasound	NN
cord-254419-qw83atrx	117	10	of	of	IN
cord-254419-qw83atrx	117	11	the	the	DT
cord-254419-qw83atrx	117	12	lower	low	JJR
cord-254419-qw83atrx	117	13	limbs	limb	NNS
cord-254419-qw83atrx	117	14	.	.	.
cord-254419-qw83atrx	118	1	Despite	despite	IN
cord-254419-qw83atrx	118	2	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	118	3	,	,	,
cord-254419-qw83atrx	118	4	high	high	JJ
cord-254419-qw83atrx	118	5	rates	rate	NNS
cord-254419-qw83atrx	118	6	of	of	IN
cord-254419-qw83atrx	118	7	deep	deep	JJ
cord-254419-qw83atrx	118	8	vein	vein	NN
cord-254419-qw83atrx	118	9	thrombosis	thrombosis	NN
cord-254419-qw83atrx	118	10	were	be	VBD
cord-254419-qw83atrx	118	11	noted	note	VBN
cord-254419-qw83atrx	118	12	in	in	IN
cord-254419-qw83atrx	118	13	all	all	DT
cord-254419-qw83atrx	118	14	patients	patient	NNS
cord-254419-qw83atrx	118	15	in	in	IN
cord-254419-qw83atrx	118	16	the	the	DT
cord-254419-qw83atrx	118	17	prophylactic	prophylactic	JJ
cord-254419-qw83atrx	118	18	dose	dose	NN
cord-254419-qw83atrx	118	19	group	group	NN
cord-254419-qw83atrx	118	20	and	and	CC
cord-254419-qw83atrx	118	21	56	56	CD
cord-254419-qw83atrx	118	22	%	%	NN
cord-254419-qw83atrx	118	23	in	in	IN
cord-254419-qw83atrx	118	24	the	the	DT
cord-254419-qw83atrx	118	25	therapeutic	therapeutic	JJ
cord-254419-qw83atrx	118	26	dose	dose	NN
cord-254419-qw83atrx	118	27	group	group	NN
cord-254419-qw83atrx	118	28	that	that	WDT
cord-254419-qw83atrx	118	29	was	be	VBD
cord-254419-qw83atrx	118	30	associated	associate	VBN
cord-254419-qw83atrx	118	31	with	with	IN
cord-254419-qw83atrx	118	32	high	high	JJ
cord-254419-qw83atrx	118	33	rates	rate	NNS
cord-254419-qw83atrx	118	34	of	of	IN
cord-254419-qw83atrx	118	35	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	118	36	embolism	embolism	NN
cord-254419-qw83atrx	118	37	[	[	-LRB-
cord-254419-qw83atrx	118	38	eight	eight	CD
cord-254419-qw83atrx	118	39	(	(	-LRB-
cord-254419-qw83atrx	118	40	23	23	CD
cord-254419-qw83atrx	118	41	%	%	NN
cord-254419-qw83atrx	118	42	)	)	-RRB-
cord-254419-qw83atrx	118	43	in	in	IN
cord-254419-qw83atrx	118	44	the	the	DT
cord-254419-qw83atrx	118	45	whole	whole	JJ
cord-254419-qw83atrx	118	46	cohort	cohort	NN
cord-254419-qw83atrx	118	47	]	]	-RRB-
cord-254419-qw83atrx	118	48	.	.	.
cord-254419-qw83atrx	119	1	A	a	DT
cord-254419-qw83atrx	119	2	larger	large	JJR
cord-254419-qw83atrx	119	3	study	study	NN
cord-254419-qw83atrx	119	4	involving	involve	VBG
cord-254419-qw83atrx	119	5	184	184	CD
cord-254419-qw83atrx	119	6	patients	patient	NNS
cord-254419-qw83atrx	119	7	admitted	admit	VBN
cord-254419-qw83atrx	119	8	in	in	IN
cord-254419-qw83atrx	119	9	three	three	CD
cord-254419-qw83atrx	119	10	hospitals	hospital	NNS
cord-254419-qw83atrx	119	11	in	in	IN
cord-254419-qw83atrx	119	12	the	the	DT
cord-254419-qw83atrx	119	13	Netherlands	Netherlands	NNP
cord-254419-qw83atrx	119	14	and	and	CC
cord-254419-qw83atrx	119	15	treated	treat	VBN
cord-254419-qw83atrx	119	16	with	with	IN
cord-254419-qw83atrx	119	17	prophylactic	prophylactic	JJ
cord-254419-qw83atrx	119	18	enoxaparin	enoxaparin	NNP
cord-254419-qw83atrx	119	19	reported	report	VBD
cord-254419-qw83atrx	119	20	an	an	DT
cord-254419-qw83atrx	119	21	incidence	incidence	NN
cord-254419-qw83atrx	119	22	of	of	IN
cord-254419-qw83atrx	119	23	31	31	CD
cord-254419-qw83atrx	119	24	%	%	NN
cord-254419-qw83atrx	119	25	and	and	CC
cord-254419-qw83atrx	119	26	25	25	CD
cord-254419-qw83atrx	119	27	%	%	NN
cord-254419-qw83atrx	119	28	of	of	IN
cord-254419-qw83atrx	119	29	deep	deep	JJ
cord-254419-qw83atrx	119	30	vein	vein	NN
cord-254419-qw83atrx	119	31	or	or	CC
cord-254419-qw83atrx	119	32	arterial	arterial	JJ
cord-254419-qw83atrx	119	33	thrombosis	thrombosis	NN
cord-254419-qw83atrx	119	34	and	and	CC
cord-254419-qw83atrx	119	35	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	119	36	embolism	embolism	NN
cord-254419-qw83atrx	119	37	,	,	,
cord-254419-qw83atrx	119	38	respectively	respectively	RB
cord-254419-qw83atrx	119	39	[	[	-LRB-
cord-254419-qw83atrx	119	40	39	39	CD
cord-254419-qw83atrx	119	41	]	]	-RRB-
cord-254419-qw83atrx	119	42	.	.	.
cord-254419-qw83atrx	120	1	A	a	DT
cord-254419-qw83atrx	120	2	follow	follow	NN
cord-254419-qw83atrx	120	3	-	-	HYPH
cord-254419-qw83atrx	120	4	up	up	NN
cord-254419-qw83atrx	120	5	of	of	IN
cord-254419-qw83atrx	120	6	the	the	DT
cord-254419-qw83atrx	120	7	same	same	JJ
cord-254419-qw83atrx	120	8	cohort	cohort	NN
cord-254419-qw83atrx	120	9	of	of	IN
cord-254419-qw83atrx	120	10	patients	patient	NNS
cord-254419-qw83atrx	120	11	was	be	VBD
cord-254419-qw83atrx	120	12	published	publish	VBN
cord-254419-qw83atrx	120	13	,	,	,
cord-254419-qw83atrx	120	14	which	which	WDT
cord-254419-qw83atrx	120	15	confirmed	confirm	VBD
cord-254419-qw83atrx	120	16	the	the	DT
cord-254419-qw83atrx	120	17	high	high	JJ
cord-254419-qw83atrx	120	18	incidence	incidence	NN
cord-254419-qw83atrx	120	19	of	of	IN
cord-254419-qw83atrx	120	20	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	120	21	embolism	embolism	NN
cord-254419-qw83atrx	120	22	(	(	-LRB-
cord-254419-qw83atrx	120	23	65/75	65/75	CD
cord-254419-qw83atrx	120	24	,	,	,
cord-254419-qw83atrx	120	25	87	87	CD
cord-254419-qw83atrx	120	26	%	%	NN
cord-254419-qw83atrx	120	27	)	)	-RRB-
cord-254419-qw83atrx	120	28	in	in	IN
cord-254419-qw83atrx	120	29	those	those	DT
cord-254419-qw83atrx	120	30	patients	patient	NNS
cord-254419-qw83atrx	120	31	diagnosed	diagnose	VBN
cord-254419-qw83atrx	120	32	with	with	IN
cord-254419-qw83atrx	120	33	deep	deep	JJ
cord-254419-qw83atrx	120	34	vein	vein	NN
cord-254419-qw83atrx	120	35	thrombosis	thrombosis	NN
cord-254419-qw83atrx	120	36	;	;	:
cord-254419-qw83atrx	120	37	and	and	CC
cord-254419-qw83atrx	120	38	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	120	39	embolism	embolism	NN
cord-254419-qw83atrx	120	40	was	be	VBD
cord-254419-qw83atrx	120	41	associated	associate	VBN
cord-254419-qw83atrx	120	42	with	with	IN
cord-254419-qw83atrx	120	43	higher	high	JJR
cord-254419-qw83atrx	120	44	risk	risk	NN
cord-254419-qw83atrx	120	45	of	of	IN
cord-254419-qw83atrx	120	46	all	all	DT
cord-254419-qw83atrx	120	47	-	-	HYPH
cord-254419-qw83atrx	120	48	cause	cause	NN
cord-254419-qw83atrx	120	49	mortality	mortality	NN
cord-254419-qw83atrx	120	50	[	[	-LRB-
cord-254419-qw83atrx	120	51	40	40	CD
cord-254419-qw83atrx	120	52	]	]	-RRB-
cord-254419-qw83atrx	120	53	.	.	.
cord-254419-qw83atrx	121	1	A	a	DT
cord-254419-qw83atrx	121	2	high	high	JJ
cord-254419-qw83atrx	121	3	rate	rate	NN
cord-254419-qw83atrx	121	4	(	(	-LRB-
cord-254419-qw83atrx	121	5	45	45	CD
cord-254419-qw83atrx	121	6	%	%	NN
cord-254419-qw83atrx	121	7	)	)	-RRB-
cord-254419-qw83atrx	121	8	of	of	IN
cord-254419-qw83atrx	121	9	lupus	lupus	NN
cord-254419-qw83atrx	121	10	anticoagulant	anticoagulant	JJ
cord-254419-qw83atrx	121	11	activity	activity	NN
cord-254419-qw83atrx	121	12	was	be	VBD
cord-254419-qw83atrx	121	13	identified	identify	VBN
cord-254419-qw83atrx	121	14	in	in	IN
cord-254419-qw83atrx	121	15	a	a	DT
cord-254419-qw83atrx	121	16	study	study	NN
cord-254419-qw83atrx	121	17	of	of	IN
cord-254419-qw83atrx	121	18	56	56	CD
cord-254419-qw83atrx	121	19	patients	patient	NNS
cord-254419-qw83atrx	121	20	when	when	WRB
cord-254419-qw83atrx	121	21	screened	screen	VBN
cord-254419-qw83atrx	121	22	by	by	IN
cord-254419-qw83atrx	121	23	a	a	DT
cord-254419-qw83atrx	121	24	sensitive	sensitive	JJ
cord-254419-qw83atrx	121	25	APTT	APTT	NNP
cord-254419-qw83atrx	121	26	test	test	NN
cord-254419-qw83atrx	121	27	and	and	CC
cord-254419-qw83atrx	121	28	direct	direct	VB
cord-254419-qw83atrx	121	29	Russel	Russel	NNP
cord-254419-qw83atrx	121	30	viper	viper	NN
cord-254419-qw83atrx	121	31	venom	venom	NN
cord-254419-qw83atrx	121	32	test	test	NN
cord-254419-qw83atrx	121	33	(	(	-LRB-
cord-254419-qw83atrx	121	34	DRVVT	DRVVT	NNP
cord-254419-qw83atrx	121	35	)	)	-RRB-
cord-254419-qw83atrx	121	36	.	.	.
cord-254419-qw83atrx	122	1	This	this	DT
cord-254419-qw83atrx	122	2	may	may	MD
cord-254419-qw83atrx	122	3	be	be	VB
cord-254419-qw83atrx	122	4	a	a	DT
cord-254419-qw83atrx	122	5	contributing	contribute	VBG
cord-254419-qw83atrx	122	6	factor	factor	NN
cord-254419-qw83atrx	122	7	in	in	IN
cord-254419-qw83atrx	122	8	the	the	DT
cord-254419-qw83atrx	122	9	development	development	NN
cord-254419-qw83atrx	122	10	of	of	IN
cord-254419-qw83atrx	122	11	thrombosis	thrombosis	NN
cord-254419-qw83atrx	122	12	in	in	IN
cord-254419-qw83atrx	122	13	some	some	DT
cord-254419-qw83atrx	122	14	patients	patient	NNS
cord-254419-qw83atrx	122	15	[	[	-LRB-
cord-254419-qw83atrx	122	16	41	41	CD
cord-254419-qw83atrx	122	17	]	]	-RRB-
cord-254419-qw83atrx	122	18	.	.	.
cord-254419-qw83atrx	123	1	Peripheral	peripheral	JJ
cord-254419-qw83atrx	123	2	arterial	arterial	JJ
cord-254419-qw83atrx	123	3	disease	disease	NN
cord-254419-qw83atrx	123	4	in	in	IN
cord-254419-qw83atrx	123	5	the	the	DT
cord-254419-qw83atrx	123	6	form	form	NN
cord-254419-qw83atrx	123	7	of	of	IN
cord-254419-qw83atrx	123	8	arteriosclerosis	arteriosclerosis	NN
cord-254419-qw83atrx	123	9	obliterans	obliterans	NN
cord-254419-qw83atrx	123	10	of	of	IN
cord-254419-qw83atrx	123	11	lower	low	JJR
cord-254419-qw83atrx	123	12	extremity	extremity	NN
cord-254419-qw83atrx	123	13	in	in	IN
cord-254419-qw83atrx	123	14	combination	combination	NN
cord-254419-qw83atrx	123	15	with	with	IN
cord-254419-qw83atrx	123	16	deep	deep	JJ
cord-254419-qw83atrx	123	17	vein	vein	NN
cord-254419-qw83atrx	123	18	thrombosis	thrombosis	NN
cord-254419-qw83atrx	123	19	has	have	VBZ
cord-254419-qw83atrx	123	20	also	also	RB
cord-254419-qw83atrx	123	21	been	be	VBN
cord-254419-qw83atrx	123	22	reported	report	VBN
cord-254419-qw83atrx	123	23	in	in	IN
cord-254419-qw83atrx	123	24	severe	severe	JJ
cord-254419-qw83atrx	123	25	infection	infection	NN
cord-254419-qw83atrx	123	26	,	,	,
cord-254419-qw83atrx	123	27	which	which	WDT
cord-254419-qw83atrx	123	28	confirms	confirm	VBZ
cord-254419-qw83atrx	123	29	the	the	DT
cord-254419-qw83atrx	123	30	presence	presence	NN
cord-254419-qw83atrx	123	31	of	of	IN
cord-254419-qw83atrx	123	32	a	a	DT
cord-254419-qw83atrx	123	33	severe	severe	JJ
cord-254419-qw83atrx	123	34	hypercoagulable	hypercoagulable	JJ
cord-254419-qw83atrx	123	35	status	status	NN
cord-254419-qw83atrx	123	36	in	in	IN
cord-254419-qw83atrx	123	37	these	these	DT
cord-254419-qw83atrx	123	38	patients	patient	NNS
cord-254419-qw83atrx	123	39	[	[	-LRB-
cord-254419-qw83atrx	123	40	42	42	CD
cord-254419-qw83atrx	123	41	]	]	-RRB-
cord-254419-qw83atrx	123	42	.	.	.
cord-254419-qw83atrx	124	1	The	the	DT
cord-254419-qw83atrx	124	2	pathophysiological	pathophysiological	JJ
cord-254419-qw83atrx	124	3	mechanism	mechanism	NN
cord-254419-qw83atrx	124	4	of	of	IN
cord-254419-qw83atrx	124	5	respiratory	respiratory	JJ
cord-254419-qw83atrx	124	6	failure	failure	NN
cord-254419-qw83atrx	124	7	in	in	IN
cord-254419-qw83atrx	124	8	COVID-19	covid-19	JJ
cord-254419-qw83atrx	124	9	infection	infection	NN
cord-254419-qw83atrx	124	10	is	be	VBZ
cord-254419-qw83atrx	124	11	not	not	RB
cord-254419-qw83atrx	124	12	clear	clear	JJ
cord-254419-qw83atrx	124	13	at	at	IN
cord-254419-qw83atrx	124	14	present	present	JJ
cord-254419-qw83atrx	124	15	but	but	CC
cord-254419-qw83atrx	124	16	there	there	EX
cord-254419-qw83atrx	124	17	is	be	VBZ
cord-254419-qw83atrx	124	18	an	an	DT
cord-254419-qw83atrx	124	19	increasing	increase	VBG
cord-254419-qw83atrx	124	20	body	body	NN
cord-254419-qw83atrx	124	21	of	of	IN
cord-254419-qw83atrx	124	22	evidence	evidence	NN
cord-254419-qw83atrx	124	23	suggesting	suggest	VBG
cord-254419-qw83atrx	124	24	microthrombosis	microthrombosis	NN
cord-254419-qw83atrx	124	25	of	of	IN
cord-254419-qw83atrx	124	26	the	the	DT
cord-254419-qw83atrx	124	27	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	124	28	vasculature	vasculature	NN
cord-254419-qw83atrx	124	29	is	be	VBZ
cord-254419-qw83atrx	124	30	a	a	DT
cord-254419-qw83atrx	124	31	key	key	JJ
cord-254419-qw83atrx	124	32	player	player	NN
cord-254419-qw83atrx	124	33	(	(	-LRB-
cord-254419-qw83atrx	124	34	Fig	Fig	NNP
cord-254419-qw83atrx	124	35	.	.	.
cord-254419-qw83atrx	124	36	1	1	CD
cord-254419-qw83atrx	124	37	)	)	-RRB-
cord-254419-qw83atrx	124	38	.	.	.
cord-254419-qw83atrx	125	1	In	in	IN
cord-254419-qw83atrx	125	2	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	125	3	pneumonitis	pneumonitis	NN
cord-254419-qw83atrx	125	4	,	,	,
cord-254419-qw83atrx	125	5	histological	histological	JJ
cord-254419-qw83atrx	125	6	changes	change	NNS
cord-254419-qw83atrx	125	7	showed	show	VBD
cord-254419-qw83atrx	125	8	pauci	pauci	NN
cord-254419-qw83atrx	125	9	-	-	HYPH
cord-254419-qw83atrx	125	10	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	125	11	septal	septal	JJ
cord-254419-qw83atrx	125	12	capillary	capillary	JJ
cord-254419-qw83atrx	125	13	injury	injury	NN
cord-254419-qw83atrx	125	14	with	with	IN
cord-254419-qw83atrx	125	15	significant	significant	JJ
cord-254419-qw83atrx	125	16	septal	septal	JJ
cord-254419-qw83atrx	125	17	capillary	capillary	JJ
cord-254419-qw83atrx	125	18	fibrin	fibrin	NN
cord-254419-qw83atrx	125	19	deposition	deposition	NN
cord-254419-qw83atrx	125	20	and	and	CC
cord-254419-qw83atrx	125	21	neutrophil	neutrophil	NN
cord-254419-qw83atrx	125	22	infiltration	infiltration	NN
cord-254419-qw83atrx	125	23	of	of	IN
cord-254419-qw83atrx	125	24	alveolar	alveolar	NN
cord-254419-qw83atrx	125	25	septa	septa	NNP
cord-254419-qw83atrx	125	26	[	[	-LRB-
cord-254419-qw83atrx	125	27	43	43	CD
cord-254419-qw83atrx	125	28	]	]	-RRB-
cord-254419-qw83atrx	125	29	.	.	.
cord-254419-qw83atrx	126	1	Viral	viral	JJ
cord-254419-qw83atrx	126	2	cytopathic	cytopathic	JJ
cord-254419-qw83atrx	126	3	and	and	CC
cord-254419-qw83atrx	126	4	classical	classical	JJ
cord-254419-qw83atrx	126	5	acute	acute	JJ
cord-254419-qw83atrx	126	6	respiratory	respiratory	JJ
cord-254419-qw83atrx	126	7	distress	distress	NN
cord-254419-qw83atrx	126	8	syndrome	syndrome	NN
cord-254419-qw83atrx	126	9	(	(	-LRB-
cord-254419-qw83atrx	126	10	ARDS	ARDS	NNP
cord-254419-qw83atrx	126	11	)	)	-RRB-
cord-254419-qw83atrx	126	12	changes	change	VBZ
cord-254419-qw83atrx	126	13	such	such	JJ
cord-254419-qw83atrx	126	14	as	as	IN
cord-254419-qw83atrx	126	15	diffuse	diffuse	JJ
cord-254419-qw83atrx	126	16	alveolar	alveolar	JJ
cord-254419-qw83atrx	126	17	damage	damage	NN
cord-254419-qw83atrx	126	18	with	with	IN
cord-254419-qw83atrx	126	19	hyaline	hyaline	JJ
cord-254419-qw83atrx	126	20	membranes	membrane	NNS
cord-254419-qw83atrx	126	21	or	or	CC
cord-254419-qw83atrx	126	22	hyperplasia	hyperplasia	NN
cord-254419-qw83atrx	126	23	of	of	IN
cord-254419-qw83atrx	126	24	type	type	NN
cord-254419-qw83atrx	126	25	II	II	NNP
cord-254419-qw83atrx	126	26	pneumocyte	pneumocyte	NNP
cord-254419-qw83atrx	126	27	were	be	VBD
cord-254419-qw83atrx	126	28	not	not	RB
cord-254419-qw83atrx	126	29	prominent	prominent	JJ
cord-254419-qw83atrx	126	30	.	.	.
cord-254419-qw83atrx	127	1	Deposits	deposit	NNS
cord-254419-qw83atrx	127	2	of	of	IN
cord-254419-qw83atrx	127	3	terminal	terminal	JJ
cord-254419-qw83atrx	127	4	complement	complement	NN
cord-254419-qw83atrx	127	5	components	component	NNS
cord-254419-qw83atrx	127	6	C5b-9	C5b-9	NNS
cord-254419-qw83atrx	127	7	,	,	,
cord-254419-qw83atrx	127	8	C4d	C4d	NNP
cord-254419-qw83atrx	127	9	,	,	,
cord-254419-qw83atrx	127	10	and	and	CC
cord-254419-qw83atrx	127	11	mannose	mannose	NN
cord-254419-qw83atrx	127	12	binding	bind	VBG
cord-254419-qw83atrx	127	13	lectin	lectin	NN
cord-254419-qw83atrx	127	14	-	-	HYPH
cord-254419-qw83atrx	127	15	associated	associate	VBN
cord-254419-qw83atrx	127	16	serine	serine	NN
cord-254419-qw83atrx	127	17	protease	protease	NN
cord-254419-qw83atrx	127	18	(	(	-LRB-
cord-254419-qw83atrx	127	19	MASP	MASP	NNP
cord-254419-qw83atrx	127	20	)	)	-RRB-
cord-254419-qw83atrx	127	21	in	in	IN
cord-254419-qw83atrx	127	22	the	the	DT
cord-254419-qw83atrx	127	23	microvasculature	microvasculature	NN
cord-254419-qw83atrx	127	24	was	be	VBD
cord-254419-qw83atrx	127	25	noted	note	VBN
cord-254419-qw83atrx	127	26	,	,	,
cord-254419-qw83atrx	127	27	suggesting	suggest	VBG
cord-254419-qw83atrx	127	28	activation	activation	NN
cord-254419-qw83atrx	127	29	of	of	IN
cord-254419-qw83atrx	127	30	the	the	DT
cord-254419-qw83atrx	127	31	alternative	alternative	NN
cord-254419-qw83atrx	127	32	and	and	CC
cord-254419-qw83atrx	127	33	lectin	lectin	NN
cord-254419-qw83atrx	127	34	-	-	HYPH
cord-254419-qw83atrx	127	35	based	base	VBN
cord-254419-qw83atrx	127	36	complement	complement	NN
cord-254419-qw83atrx	127	37	pathways	pathway	NNS
cord-254419-qw83atrx	127	38	.	.	.
cord-254419-qw83atrx	128	1	Another	another	DT
cord-254419-qw83atrx	128	2	study	study	NN
cord-254419-qw83atrx	128	3	with	with	IN
cord-254419-qw83atrx	128	4	lung	lung	NN
cord-254419-qw83atrx	128	5	autopsy	autopsy	JJ
cord-254419-qw83atrx	128	6	findings	finding	NNS
cord-254419-qw83atrx	128	7	from	from	IN
cord-254419-qw83atrx	128	8	ten	ten	CD
cord-254419-qw83atrx	128	9	patients	patient	NNS
cord-254419-qw83atrx	128	10	showed	show	VBD
cord-254419-qw83atrx	128	11	predominantly	predominantly	RB
cord-254419-qw83atrx	128	12	proliferative	proliferative	JJ
cord-254419-qw83atrx	128	13	diffuse	diffuse	JJ
cord-254419-qw83atrx	128	14	alveolar	alveolar	JJ
cord-254419-qw83atrx	128	15	damage	damage	NN
cord-254419-qw83atrx	128	16	,	,	,
cord-254419-qw83atrx	128	17	epithelial	epithelial	JJ
cord-254419-qw83atrx	128	18	viral	viral	JJ
cord-254419-qw83atrx	128	19	cytopathic	cytopathic	JJ
cord-254419-qw83atrx	128	20	effects	effect	NNS
cord-254419-qw83atrx	128	21	of	of	IN
cord-254419-qw83atrx	128	22	small	small	JJ
cord-254419-qw83atrx	128	23	airway	airway	NN
cord-254419-qw83atrx	128	24	epithelium	epithelium	NN
cord-254419-qw83atrx	128	25	,	,	,
cord-254419-qw83atrx	128	26	but	but	CC
cord-254419-qw83atrx	128	27	minimal	minimal	JJ
cord-254419-qw83atrx	128	28	lymphocytic	lymphocytic	JJ
cord-254419-qw83atrx	128	29	infiltration	infiltration	NN
cord-254419-qw83atrx	128	30	[	[	-LRB-
cord-254419-qw83atrx	128	31	44	44	CD
cord-254419-qw83atrx	128	32	]	]	-RRB-
cord-254419-qw83atrx	128	33	.	.	.
cord-254419-qw83atrx	129	1	The	the	DT
cord-254419-qw83atrx	129	2	lung	lung	NN
cord-254419-qw83atrx	129	3	injury	injury	NN
cord-254419-qw83atrx	129	4	observed	observe	VBD
cord-254419-qw83atrx	129	5	in	in	IN
cord-254419-qw83atrx	129	6	this	this	DT
cord-254419-qw83atrx	129	7	study	study	NN
cord-254419-qw83atrx	129	8	was	be	VBD
cord-254419-qw83atrx	129	9	secondary	secondary	JJ
cord-254419-qw83atrx	129	10	to	to	IN
cord-254419-qw83atrx	129	11	formation	formation	NN
cord-254419-qw83atrx	129	12	of	of	IN
cord-254419-qw83atrx	129	13	fibrinous	fibrinous	NNP
cord-254419-qw83atrx	129	14	thrombi	thrombi	NNP
cord-254419-qw83atrx	129	15	in	in	IN
cord-254419-qw83atrx	129	16	small	small	JJ
cord-254419-qw83atrx	129	17	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	129	18	arteriole	arteriole	NN
cord-254419-qw83atrx	129	19	,	,	,
cord-254419-qw83atrx	129	20	endothelial	endothelial	JJ
cord-254419-qw83atrx	129	21	tumefaction	tumefaction	NN
cord-254419-qw83atrx	129	22	,	,	,
cord-254419-qw83atrx	129	23	and	and	CC
cord-254419-qw83atrx	129	24	megakaryocyte	megakaryocyte	NNP
cord-254419-qw83atrx	129	25	aggregation	aggregation	NN
cord-254419-qw83atrx	129	26	in	in	IN
cord-254419-qw83atrx	129	27	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	129	28	capillaries	capillary	NNS
cord-254419-qw83atrx	129	29	,	,	,
cord-254419-qw83atrx	129	30	suggesting	suggest	VBG
cord-254419-qw83atrx	129	31	activation	activation	NN
cord-254419-qw83atrx	129	32	of	of	IN
cord-254419-qw83atrx	129	33	coagulation	coagulation	NN
cord-254419-qw83atrx	129	34	cascade	cascade	NN
cord-254419-qw83atrx	129	35	with	with	IN
cord-254419-qw83atrx	129	36	microthrombus	microthrombus	NNP
cord-254419-qw83atrx	129	37	formation	formation	NN
cord-254419-qw83atrx	129	38	.	.	.
cord-254419-qw83atrx	130	1	The	the	DT
cord-254419-qw83atrx	130	2	term	term	NN
cord-254419-qw83atrx	130	3	'	'	''
cord-254419-qw83atrx	130	4	'	'	``
cord-254419-qw83atrx	130	5	microvascular	microvascular	JJ
cord-254419-qw83atrx	130	6	COVID-19	covid-19	JJ
cord-254419-qw83atrx	130	7	lung	lung	NN
cord-254419-qw83atrx	130	8	vessels	vessel	NNS
cord-254419-qw83atrx	130	9	obstructive	obstructive	JJ
cord-254419-qw83atrx	130	10	thrombo	thrombo	JJ
cord-254419-qw83atrx	130	11	-	-	HYPH
cord-254419-qw83atrx	130	12	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	130	13	syndrome	syndrome	NN
cord-254419-qw83atrx	130	14	(	(	-LRB-
cord-254419-qw83atrx	130	15	microCLOTS	microCLOTS	NNP
cord-254419-qw83atrx	130	16	)	)	-RRB-
cord-254419-qw83atrx	130	17	'	'	''
cord-254419-qw83atrx	130	18	'	'	''
cord-254419-qw83atrx	130	19	has	have	VBZ
cord-254419-qw83atrx	130	20	been	be	VBN
cord-254419-qw83atrx	130	21	proposed	propose	VBN
cord-254419-qw83atrx	130	22	to	to	TO
cord-254419-qw83atrx	130	23	describe	describe	VB
cord-254419-qw83atrx	130	24	the	the	DT
cord-254419-qw83atrx	130	25	thrombo	thrombo	JJ
cord-254419-qw83atrx	130	26	-	-	HYPH
cord-254419-qw83atrx	130	27	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	130	28	lung	lung	NN
cord-254419-qw83atrx	130	29	pathology	pathology	NN
cord-254419-qw83atrx	130	30	[	[	-LRB-
cord-254419-qw83atrx	130	31	5	5	CD
cord-254419-qw83atrx	130	32	]	]	-RRB-
cord-254419-qw83atrx	130	33	.	.	.
cord-254419-qw83atrx	131	1	The	the	DT
cord-254419-qw83atrx	131	2	working	work	VBG
cord-254419-qw83atrx	131	3	hypothesis	hypothesis	NN
cord-254419-qw83atrx	131	4	is	be	VBZ
cord-254419-qw83atrx	131	5	that	that	IN
cord-254419-qw83atrx	131	6	in	in	IN
cord-254419-qw83atrx	131	7	individuals	individual	NNS
cord-254419-qw83atrx	131	8	at	at	IN
cord-254419-qw83atrx	131	9	risk	risk	NN
cord-254419-qw83atrx	131	10	of	of	IN
cord-254419-qw83atrx	131	11	severe	severe	JJ
cord-254419-qw83atrx	131	12	disease	disease	NN
cord-254419-qw83atrx	131	13	,	,	,
cord-254419-qw83atrx	131	14	an	an	DT
cord-254419-qw83atrx	131	15	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	131	16	reaction	reaction	NN
cord-254419-qw83atrx	131	17	and	and	CC
cord-254419-qw83atrx	131	18	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	131	19	microvascular	microvascular	JJ
cord-254419-qw83atrx	131	20	thrombosis	thrombosis	NN
cord-254419-qw83atrx	131	21	leading	lead	VBG
cord-254419-qw83atrx	131	22	to	to	IN
cord-254419-qw83atrx	131	23	alveolar	alveolar	JJ
cord-254419-qw83atrx	131	24	damage	damage	NN
cord-254419-qw83atrx	131	25	is	be	VBZ
cord-254419-qw83atrx	131	26	initiated	initiate	VBN
cord-254419-qw83atrx	131	27	.	.	.
cord-254419-qw83atrx	132	1	Because	because	IN
cord-254419-qw83atrx	132	2	of	of	IN
cord-254419-qw83atrx	132	3	the	the	DT
cord-254419-qw83atrx	132	4	systemic	systemic	JJ
cord-254419-qw83atrx	132	5	endotheliitis	endotheliitis	NN
cord-254419-qw83atrx	132	6	,	,	,
cord-254419-qw83atrx	132	7	this	this	DT
cord-254419-qw83atrx	132	8	thrombo	thrombo	JJ
cord-254419-qw83atrx	132	9	-	-	HYPH
cord-254419-qw83atrx	132	10	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	132	11	syndrome	syndrome	NN
cord-254419-qw83atrx	132	12	may	may	MD
cord-254419-qw83atrx	132	13	progress	progress	VB
cord-254419-qw83atrx	132	14	to	to	TO
cord-254419-qw83atrx	132	15	involve	involve	VB
cord-254419-qw83atrx	132	16	a	a	DT
cord-254419-qw83atrx	132	17	microvascular	microvascular	JJ
cord-254419-qw83atrx	132	18	bed	bed	NN
cord-254419-qw83atrx	132	19	of	of	IN
cord-254419-qw83atrx	132	20	other	other	JJ
cord-254419-qw83atrx	132	21	major	major	JJ
cord-254419-qw83atrx	132	22	organs	organ	NNS
cord-254419-qw83atrx	132	23	contributing	contribute	VBG
cord-254419-qw83atrx	132	24	to	to	IN
cord-254419-qw83atrx	132	25	multi	multi	JJ
cord-254419-qw83atrx	132	26	-	-	JJ
cord-254419-qw83atrx	132	27	organ	organ	JJ
cord-254419-qw83atrx	132	28	failure	failure	NN
cord-254419-qw83atrx	132	29	.	.	.
cord-254419-qw83atrx	133	1	It	-PRON-	PRP
cord-254419-qw83atrx	133	2	is	be	VBZ
cord-254419-qw83atrx	133	3	increasingly	increasingly	RB
cord-254419-qw83atrx	133	4	recognized	recognize	VBN
cord-254419-qw83atrx	133	5	that	that	IN
cord-254419-qw83atrx	133	6	in	in	IN
cord-254419-qw83atrx	133	7	this	this	DT
cord-254419-qw83atrx	133	8	infection	infection	NN
cord-254419-qw83atrx	133	9	,	,	,
cord-254419-qw83atrx	133	10	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	133	11	thrombus	thrombus	NN
cord-254419-qw83atrx	133	12	develops	develop	VBZ
cord-254419-qw83atrx	133	13	due	due	IN
cord-254419-qw83atrx	133	14	to	to	IN
cord-254419-qw83atrx	133	15	a	a	DT
cord-254419-qw83atrx	133	16	local	local	JJ
cord-254419-qw83atrx	133	17	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	133	18	reaction	reaction	NN
cord-254419-qw83atrx	133	19	.	.	.
cord-254419-qw83atrx	134	1	Platelets	platelet	NNS
cord-254419-qw83atrx	134	2	interacting	interact	VBG
cord-254419-qw83atrx	134	3	with	with	IN
cord-254419-qw83atrx	134	4	the	the	DT
cord-254419-qw83atrx	134	5	vascular	vascular	JJ
cord-254419-qw83atrx	134	6	wall	wall	NN
cord-254419-qw83atrx	134	7	,	,	,
cord-254419-qw83atrx	134	8	leukocytes	leukocyte	NNS
cord-254419-qw83atrx	134	9	,	,	,
cord-254419-qw83atrx	134	10	factor	factor	NN
cord-254419-qw83atrx	134	11	XIIa	XIIa	NNS
cord-254419-qw83atrx	134	12	,	,	,
cord-254419-qw83atrx	134	13	Von	Von	NNP
cord-254419-qw83atrx	134	14	Willebrand	Willebrand	NNP
cord-254419-qw83atrx	134	15	factor	factor	NN
cord-254419-qw83atrx	134	16	and	and	CC
cord-254419-qw83atrx	134	17	complement	complement	NN
cord-254419-qw83atrx	134	18	leads	lead	VBZ
cord-254419-qw83atrx	134	19	to	to	IN
cord-254419-qw83atrx	134	20	an	an	DT
cord-254419-qw83atrx	134	21	intense	intense	JJ
cord-254419-qw83atrx	134	22	thrombo	thrombo	NN
cord-254419-qw83atrx	134	23	-	-	HYPH
cord-254419-qw83atrx	134	24	inflammation	inflammation	NN
cord-254419-qw83atrx	134	25	,	,	,
cord-254419-qw83atrx	134	26	which	which	WDT
cord-254419-qw83atrx	134	27	is	be	VBZ
cord-254419-qw83atrx	134	28	a	a	DT
cord-254419-qw83atrx	134	29	direct	direct	JJ
cord-254419-qw83atrx	134	30	consequence	consequence	NN
cord-254419-qw83atrx	134	31	of	of	IN
cord-254419-qw83atrx	134	32	vascular	vascular	JJ
cord-254419-qw83atrx	134	33	damage	damage	NN
cord-254419-qw83atrx	134	34	associated	associate	VBN
cord-254419-qw83atrx	134	35	with	with	IN
cord-254419-qw83atrx	134	36	viral	viral	JJ
cord-254419-qw83atrx	134	37	infection	infection	NN
cord-254419-qw83atrx	134	38	[	[	-LRB-
cord-254419-qw83atrx	134	39	45	45	CD
cord-254419-qw83atrx	134	40	]	]	-RRB-
cord-254419-qw83atrx	134	41	.	.	.
cord-254419-qw83atrx	135	1	Because	because	IN
cord-254419-qw83atrx	135	2	of	of	IN
cord-254419-qw83atrx	135	3	the	the	DT
cord-254419-qw83atrx	135	4	unusually	unusually	RB
cord-254419-qw83atrx	135	5	high	high	JJ
cord-254419-qw83atrx	135	6	incidence	incidence	NN
cord-254419-qw83atrx	135	7	of	of	IN
cord-254419-qw83atrx	135	8	thrombotic	thrombotic	JJ
cord-254419-qw83atrx	135	9	complications	complication	NNS
cord-254419-qw83atrx	135	10	despite	despite	IN
cord-254419-qw83atrx	135	11	prophylactic	prophylactic	JJ
cord-254419-qw83atrx	135	12	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	135	13	,	,	,
cord-254419-qw83atrx	135	14	some	some	DT
cord-254419-qw83atrx	135	15	centers	center	NNS
cord-254419-qw83atrx	135	16	recommend	recommend	VBP
cord-254419-qw83atrx	135	17	a	a	DT
cord-254419-qw83atrx	135	18	higher	high	JJR
cord-254419-qw83atrx	135	19	dose	dose	NN
cord-254419-qw83atrx	135	20	for	for	IN
cord-254419-qw83atrx	135	21	prophylactic	prophylactic	JJ
cord-254419-qw83atrx	135	22	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	135	23	(	(	-LRB-
cord-254419-qw83atrx	135	24	e.g.	e.g.	RB
cord-254419-qw83atrx	135	25	,	,	,
cord-254419-qw83atrx	135	26	enoxaparin	enoxaparin	NNP
cord-254419-qw83atrx	135	27	40	40	CD
cord-254419-qw83atrx	135	28	mg	mg	NNS
cord-254419-qw83atrx	135	29	twice	twice	PDT
cord-254419-qw83atrx	135	30	a	a	DT
cord-254419-qw83atrx	135	31	day	day	NN
cord-254419-qw83atrx	135	32	rather	rather	RB
cord-254419-qw83atrx	135	33	than	than	IN
cord-254419-qw83atrx	135	34	the	the	DT
cord-254419-qw83atrx	135	35	conventional	conventional	JJ
cord-254419-qw83atrx	135	36	dosing	dosing	NN
cord-254419-qw83atrx	135	37	of	of	IN
cord-254419-qw83atrx	135	38	40	40	CD
cord-254419-qw83atrx	135	39	mg	mg	NNS
cord-254419-qw83atrx	135	40	once	once	RB
cord-254419-qw83atrx	135	41	a	a	DT
cord-254419-qw83atrx	135	42	day	day	NN
cord-254419-qw83atrx	135	43	)	)	-RRB-
cord-254419-qw83atrx	136	1	[	[	-LRB-
cord-254419-qw83atrx	136	2	39	39	CD
cord-254419-qw83atrx	136	3	]	]	-RRB-
cord-254419-qw83atrx	136	4	.	.	.
cord-254419-qw83atrx	137	1	Although	although	IN
cord-254419-qw83atrx	137	2	there	there	EX
cord-254419-qw83atrx	137	3	appears	appear	VBZ
cord-254419-qw83atrx	137	4	to	to	TO
cord-254419-qw83atrx	137	5	be	be	VB
cord-254419-qw83atrx	137	6	a	a	DT
cord-254419-qw83atrx	137	7	consensus	consensus	NN
cord-254419-qw83atrx	137	8	about	about	IN
cord-254419-qw83atrx	137	9	treating	treat	VBG
cord-254419-qw83atrx	137	10	all	all	DT
cord-254419-qw83atrx	137	11	hospitalized	hospitalize	VBN
cord-254419-qw83atrx	137	12	patients	patient	NNS
cord-254419-qw83atrx	137	13	with	with	IN
cord-254419-qw83atrx	137	14	some	some	DT
cord-254419-qw83atrx	137	15	form	form	NN
cord-254419-qw83atrx	137	16	of	of	IN
cord-254419-qw83atrx	137	17	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	137	18	,	,	,
cord-254419-qw83atrx	137	19	dosing	dosing	NN
cord-254419-qw83atrx	137	20	strategies	strategy	NNS
cord-254419-qw83atrx	137	21	are	be	VBP
cord-254419-qw83atrx	137	22	not	not	RB
cord-254419-qw83atrx	137	23	yet	yet	RB
cord-254419-qw83atrx	137	24	clear	clear	JJ
cord-254419-qw83atrx	137	25	.	.	.
cord-254419-qw83atrx	138	1	The	the	DT
cord-254419-qw83atrx	138	2	ISTH	ISTH	NNP
cord-254419-qw83atrx	138	3	interim	interim	JJ
cord-254419-qw83atrx	138	4	guidelines	guideline	NNS
cord-254419-qw83atrx	138	5	and	and	CC
cord-254419-qw83atrx	138	6	some	some	DT
cord-254419-qw83atrx	138	7	other	other	JJ
cord-254419-qw83atrx	138	8	expert	expert	JJ
cord-254419-qw83atrx	138	9	opinions	opinion	NNS
cord-254419-qw83atrx	138	10	have	have	VBP
cord-254419-qw83atrx	138	11	proposed	propose	VBN
cord-254419-qw83atrx	138	12	a	a	DT
cord-254419-qw83atrx	138	13	day	day	NN
cord-254419-qw83atrx	138	14	)	)	-RRB-
cord-254419-qw83atrx	138	15	.	.	.
cord-254419-qw83atrx	139	1	However	however	RB
cord-254419-qw83atrx	139	2	,	,	,
cord-254419-qw83atrx	139	3	this	this	DT
cord-254419-qw83atrx	139	4	approach	approach	NN
cord-254419-qw83atrx	139	5	of	of	IN
cord-254419-qw83atrx	139	6	either	either	DT
cord-254419-qw83atrx	139	7	standard	standard	JJ
cord-254419-qw83atrx	139	8	or	or	CC
cord-254419-qw83atrx	139	9	intermediate	intermediate	JJ
cord-254419-qw83atrx	139	10	dose	dose	NN
cord-254419-qw83atrx	139	11	prophylaxis	prophylaxis	NN
cord-254419-qw83atrx	139	12	has	have	VBZ
cord-254419-qw83atrx	139	13	been	be	VBN
cord-254419-qw83atrx	139	14	questioned	question	VBN
cord-254419-qw83atrx	139	15	and	and	CC
cord-254419-qw83atrx	139	16	systemic	systemic	JJ
cord-254419-qw83atrx	139	17	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	139	18	with	with	IN
cord-254419-qw83atrx	139	19	unfractionated	unfractionated	JJ
cord-254419-qw83atrx	139	20	heparin	heparin	JJ
cord-254419-qw83atrx	139	21	infusion	infusion	NN
cord-254419-qw83atrx	139	22	is	be	VBZ
cord-254419-qw83atrx	139	23	routinely	routinely	RB
cord-254419-qw83atrx	139	24	used	use	VBN
cord-254419-qw83atrx	139	25	for	for	IN
cord-254419-qw83atrx	139	26	critically	critically	RB
cord-254419-qw83atrx	139	27	ill	ill	JJ
cord-254419-qw83atrx	139	28	patients	patient	NNS
cord-254419-qw83atrx	139	29	in	in	IN
cord-254419-qw83atrx	139	30	some	some	DT
cord-254419-qw83atrx	139	31	centers	center	NNS
cord-254419-qw83atrx	139	32	[	[	-LRB-
cord-254419-qw83atrx	139	33	48	48	CD
cord-254419-qw83atrx	139	34	]	]	-RRB-
cord-254419-qw83atrx	139	35	.	.	.
cord-254419-qw83atrx	140	1	This	this	DT
cord-254419-qw83atrx	140	2	approach	approach	NN
cord-254419-qw83atrx	140	3	is	be	VBZ
cord-254419-qw83atrx	140	4	recommended	recommend	VBN
cord-254419-qw83atrx	140	5	because	because	IN
cord-254419-qw83atrx	140	6	CAC	CAC	NNP
cord-254419-qw83atrx	140	7	is	be	VBZ
cord-254419-qw83atrx	140	8	considered	consider	VBN
cord-254419-qw83atrx	140	9	to	to	TO
cord-254419-qw83atrx	140	10	be	be	VB
cord-254419-qw83atrx	140	11	an	an	DT
cord-254419-qw83atrx	140	12	overwhelmingly	overwhelmingly	RB
cord-254419-qw83atrx	140	13	thrombotic	thrombotic	JJ
cord-254419-qw83atrx	140	14	DIC	DIC	NNP
cord-254419-qw83atrx	140	15	with	with	IN
cord-254419-qw83atrx	140	16	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	140	17	embolism	embolism	NN
cord-254419-qw83atrx	140	18	being	be	VBG
cord-254419-qw83atrx	140	19	difficult	difficult	JJ
cord-254419-qw83atrx	140	20	to	to	TO
cord-254419-qw83atrx	140	21	diagnose	diagnose	VB
cord-254419-qw83atrx	140	22	in	in	IN
cord-254419-qw83atrx	140	23	patients	patient	NNS
cord-254419-qw83atrx	140	24	who	who	WP
cord-254419-qw83atrx	140	25	require	require	VBP
cord-254419-qw83atrx	140	26	mechanical	mechanical	JJ
cord-254419-qw83atrx	140	27	ventilation	ventilation	NN
cord-254419-qw83atrx	140	28	.	.	.
cord-254419-qw83atrx	141	1	Also	also	RB
cord-254419-qw83atrx	141	2	,	,	,
cord-254419-qw83atrx	141	3	bleeding	bleed	VBG
cord-254419-qw83atrx	141	4	is	be	VBZ
cord-254419-qw83atrx	141	5	noted	note	VBN
cord-254419-qw83atrx	141	6	to	to	TO
cord-254419-qw83atrx	141	7	be	be	VB
cord-254419-qw83atrx	141	8	rare	rare	JJ
cord-254419-qw83atrx	141	9	even	even	RB
cord-254419-qw83atrx	141	10	in	in	IN
cord-254419-qw83atrx	141	11	sick	sick	JJ
cord-254419-qw83atrx	141	12	patients	patient	NNS
cord-254419-qw83atrx	141	13	,	,	,
cord-254419-qw83atrx	141	14	and	and	CC
cord-254419-qw83atrx	141	15	hence	hence	RB
cord-254419-qw83atrx	141	16	the	the	DT
cord-254419-qw83atrx	141	17	risk	risk	NN
cord-254419-qw83atrx	141	18	of	of	IN
cord-254419-qw83atrx	141	19	therapeutic	therapeutic	JJ
cord-254419-qw83atrx	141	20	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	141	21	is	be	VBZ
cord-254419-qw83atrx	141	22	not	not	RB
cord-254419-qw83atrx	141	23	as	as	RB
cord-254419-qw83atrx	141	24	great	great	JJ
cord-254419-qw83atrx	141	25	as	as	IN
cord-254419-qw83atrx	141	26	other	other	JJ
cord-254419-qw83atrx	141	27	patients	patient	NNS
cord-254419-qw83atrx	141	28	with	with	IN
cord-254419-qw83atrx	141	29	sepsis	sepsis	NN
cord-254419-qw83atrx	141	30	-	-	HYPH
cord-254419-qw83atrx	141	31	induced	induce	VBN
cord-254419-qw83atrx	141	32	coagulopathy	coagulopathy	NN
cord-254419-qw83atrx	141	33	.	.	.
cord-254419-qw83atrx	142	1	Hyperfibrinogenemia	Hyperfibrinogenemia	NNP
cord-254419-qw83atrx	142	2	with	with	IN
cord-254419-qw83atrx	142	3	fibrin	fibrin	NN
cord-254419-qw83atrx	142	4	deposition	deposition	NN
cord-254419-qw83atrx	142	5	in	in	IN
cord-254419-qw83atrx	142	6	the	the	DT
cord-254419-qw83atrx	142	7	air	air	NN
cord-254419-qw83atrx	142	8	spaces	space	NNS
cord-254419-qw83atrx	142	9	and	and	CC
cord-254419-qw83atrx	142	10	lung	lung	NN
cord-254419-qw83atrx	142	11	parenchyma	parenchyma	NN
cord-254419-qw83atrx	142	12	due	due	IN
cord-254419-qw83atrx	142	13	to	to	IN
cord-254419-qw83atrx	142	14	a	a	DT
cord-254419-qw83atrx	142	15	hypofibrinolytic	hypofibrinolytic	JJ
cord-254419-qw83atrx	142	16	state	state	NN
cord-254419-qw83atrx	142	17	is	be	VBZ
cord-254419-qw83atrx	142	18	well	well	RB
cord-254419-qw83atrx	142	19	recognized	recognize	VBN
cord-254419-qw83atrx	142	20	in	in	IN
cord-254419-qw83atrx	142	21	these	these	DT
cord-254419-qw83atrx	142	22	patients	patient	NNS
cord-254419-qw83atrx	142	23	[	[	-LRB-
cord-254419-qw83atrx	142	24	49	49	CD
cord-254419-qw83atrx	142	25	]	]	-RRB-
cord-254419-qw83atrx	142	26	.	.	.
cord-254419-qw83atrx	143	1	Fibrin	fibrin	NN
cord-254419-qw83atrx	143	2	deposition	deposition	NN
cord-254419-qw83atrx	143	3	can	can	MD
cord-254419-qw83atrx	143	4	occur	occur	VB
cord-254419-qw83atrx	143	5	even	even	RB
cord-254419-qw83atrx	143	6	before	before	IN
cord-254419-qw83atrx	143	7	appearance	appearance	NN
cord-254419-qw83atrx	143	8	of	of	IN
cord-254419-qw83atrx	143	9	symptoms	symptom	NNS
cord-254419-qw83atrx	143	10	of	of	IN
cord-254419-qw83atrx	143	11	infection	infection	NN
cord-254419-qw83atrx	143	12	as	as	IN
cord-254419-qw83atrx	143	13	identified	identify	VBN
cord-254419-qw83atrx	143	14	in	in	IN
cord-254419-qw83atrx	143	15	lung	lung	NN
cord-254419-qw83atrx	143	16	biopsy	biopsy	NN
cord-254419-qw83atrx	143	17	specimens	specimen	NNS
cord-254419-qw83atrx	143	18	of	of	IN
cord-254419-qw83atrx	143	19	two	two	CD
cord-254419-qw83atrx	143	20	patients	patient	NNS
cord-254419-qw83atrx	143	21	with	with	IN
cord-254419-qw83atrx	143	22	lung	lung	NN
cord-254419-qw83atrx	143	23	cancer	cancer	NN
cord-254419-qw83atrx	143	24	[	[	-LRB-
cord-254419-qw83atrx	143	25	50	50	CD
cord-254419-qw83atrx	143	26	]	]	-RRB-
cord-254419-qw83atrx	143	27	.	.	.
cord-254419-qw83atrx	144	1	There	there	EX
cord-254419-qw83atrx	144	2	is	be	VBZ
cord-254419-qw83atrx	144	3	limited	limited	JJ
cord-254419-qw83atrx	144	4	experience	experience	NN
cord-254419-qw83atrx	144	5	in	in	IN
cord-254419-qw83atrx	144	6	the	the	DT
cord-254419-qw83atrx	144	7	use	use	NN
cord-254419-qw83atrx	144	8	of	of	IN
cord-254419-qw83atrx	144	9	fibrinolytic	fibrinolytic	JJ
cord-254419-qw83atrx	144	10	therapy	therapy	NN
cord-254419-qw83atrx	144	11	with	with	IN
cord-254419-qw83atrx	144	12	tissue	tissue	NN
cord-254419-qw83atrx	144	13	plasminogen	plasminogen	NN
cord-254419-qw83atrx	144	14	activator	activator	NN
cord-254419-qw83atrx	144	15	(	(	-LRB-
cord-254419-qw83atrx	144	16	TPA	TPA	NNP
cord-254419-qw83atrx	144	17	)	)	-RRB-
cord-254419-qw83atrx	144	18	.	.	.
cord-254419-qw83atrx	145	1	It	-PRON-	PRP
cord-254419-qw83atrx	145	2	has	have	VBZ
cord-254419-qw83atrx	145	3	been	be	VBN
cord-254419-qw83atrx	145	4	used	use	VBN
cord-254419-qw83atrx	145	5	in	in	IN
cord-254419-qw83atrx	145	6	off	off	IN
cord-254419-qw83atrx	145	7	-	-	HYPH
cord-254419-qw83atrx	145	8	label	label	NN
cord-254419-qw83atrx	145	9	fashion	fashion	NN
cord-254419-qw83atrx	145	10	in	in	IN
cord-254419-qw83atrx	145	11	three	three	CD
cord-254419-qw83atrx	145	12	patients	patient	NNS
cord-254419-qw83atrx	145	13	with	with	IN
cord-254419-qw83atrx	145	14	a	a	DT
cord-254419-qw83atrx	145	15	noted	note	VBN
cord-254419-qw83atrx	145	16	improvement	improvement	NN
cord-254419-qw83atrx	145	17	in	in	IN
cord-254419-qw83atrx	145	18	oxygenation	oxygenation	NN
cord-254419-qw83atrx	145	19	[	[	-LRB-
cord-254419-qw83atrx	145	20	increase	increase	NN
cord-254419-qw83atrx	145	21	in	in	IN
cord-254419-qw83atrx	145	22	partial	partial	JJ
cord-254419-qw83atrx	145	23	pressure	pressure	NN
cord-254419-qw83atrx	145	24	of	of	IN
cord-254419-qw83atrx	145	25	oxygen	oxygen	NN
cord-254419-qw83atrx	145	26	(	(	-LRB-
cord-254419-qw83atrx	145	27	PaO	PaO	NNP
cord-254419-qw83atrx	145	28	2	2	CD
cord-254419-qw83atrx	145	29	)	)	-RRB-
cord-254419-qw83atrx	145	30	/	/	SYM
cord-254419-qw83atrx	145	31	fraction	fraction	NN
cord-254419-qw83atrx	145	32	of	of	IN
cord-254419-qw83atrx	145	33	inspired	inspire	VBN
cord-254419-qw83atrx	145	34	oxygen	oxygen	NN
cord-254419-qw83atrx	145	35	(	(	-LRB-
cord-254419-qw83atrx	145	36	FiO	FiO	NNP
cord-254419-qw83atrx	145	37	2	2	CD
cord-254419-qw83atrx	145	38	)	)	-RRB-
cord-254419-qw83atrx	145	39	(	(	-LRB-
cord-254419-qw83atrx	145	40	P	p	NN
cord-254419-qw83atrx	145	41	/	/	SYM
cord-254419-qw83atrx	145	42	F	F	NNP
cord-254419-qw83atrx	145	43	)	)	-RRB-
cord-254419-qw83atrx	145	44	ratio	ratio	NN
cord-254419-qw83atrx	145	45	]	]	-RRB-
cord-254419-qw83atrx	145	46	[	[	-LRB-
cord-254419-qw83atrx	145	47	51	51	CD
cord-254419-qw83atrx	145	48	]	]	-RRB-
cord-254419-qw83atrx	145	49	.	.	.
cord-254419-qw83atrx	146	1	Nebulized	Nebulized	NNP
cord-254419-qw83atrx	146	2	TPA	TPA	NNP
cord-254419-qw83atrx	146	3	may	may	MD
cord-254419-qw83atrx	146	4	be	be	VB
cord-254419-qw83atrx	146	5	effective	effective	JJ
cord-254419-qw83atrx	146	6	with	with	IN
cord-254419-qw83atrx	146	7	less	less	JJR
cord-254419-qw83atrx	146	8	risk	risk	NN
cord-254419-qw83atrx	146	9	of	of	IN
cord-254419-qw83atrx	146	10	bleeding	bleed	VBG
cord-254419-qw83atrx	146	11	and	and	CC
cord-254419-qw83atrx	146	12	this	this	DT
cord-254419-qw83atrx	146	13	is	be	VBZ
cord-254419-qw83atrx	146	14	currently	currently	RB
cord-254419-qw83atrx	146	15	being	be	VBG
cord-254419-qw83atrx	146	16	examined	examine	VBN
cord-254419-qw83atrx	146	17	in	in	IN
cord-254419-qw83atrx	146	18	a	a	DT
cord-254419-qw83atrx	146	19	clinical	clinical	JJ
cord-254419-qw83atrx	146	20	trial	trial	NN
cord-254419-qw83atrx	146	21	(	(	-LRB-
cord-254419-qw83atrx	146	22	NCT04356833	NCT04356833	NNP
cord-254419-qw83atrx	146	23	)	)	-RRB-
cord-254419-qw83atrx	146	24	.	.	.
cord-254419-qw83atrx	147	1	A	a	DT
cord-254419-qw83atrx	147	2	recent	recent	JJ
cord-254419-qw83atrx	147	3	review	review	NN
cord-254419-qw83atrx	147	4	has	have	VBZ
cord-254419-qw83atrx	147	5	recommended	recommend	VBN
cord-254419-qw83atrx	147	6	standard	standard	JJ
cord-254419-qw83atrx	147	7	prophylactic	prophylactic	JJ
cord-254419-qw83atrx	147	8	dose	dose	NN
cord-254419-qw83atrx	147	9	of	of	IN
cord-254419-qw83atrx	147	10	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	147	11	in	in	IN
cord-254419-qw83atrx	147	12	hospitalized	hospitalize	VBN
cord-254419-qw83atrx	147	13	but	but	CC
cord-254419-qw83atrx	147	14	well	well	JJ
cord-254419-qw83atrx	147	15	patients	patient	NNS
cord-254419-qw83atrx	147	16	,	,	,
cord-254419-qw83atrx	147	17	intermediate	intermediate	JJ
cord-254419-qw83atrx	147	18	dose	dose	NN
cord-254419-qw83atrx	147	19	prophylaxis	prophylaxis	NN
cord-254419-qw83atrx	147	20	to	to	IN
cord-254419-qw83atrx	147	21	those	those	DT
cord-254419-qw83atrx	147	22	admitted	admit	VBN
cord-254419-qw83atrx	147	23	in	in	IN
cord-254419-qw83atrx	147	24	ICU	ICU	NNP
cord-254419-qw83atrx	147	25	and	and	CC
cord-254419-qw83atrx	147	26	ARDS	ARDS	NNP
cord-254419-qw83atrx	147	27	,	,	,
cord-254419-qw83atrx	147	28	and	and	CC
cord-254419-qw83atrx	147	29	therapeutic	therapeutic	JJ
cord-254419-qw83atrx	147	30	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	147	31	to	to	IN
cord-254419-qw83atrx	147	32	those	those	DT
cord-254419-qw83atrx	147	33	with	with	IN
cord-254419-qw83atrx	147	34	presumed	presume	VBN
cord-254419-qw83atrx	147	35	or	or	CC
cord-254419-qw83atrx	147	36	confirmed	confirm	VBN
cord-254419-qw83atrx	147	37	deep	deep	JJ
cord-254419-qw83atrx	147	38	vein	vein	NN
cord-254419-qw83atrx	147	39	thrombosis	thrombosis	NN
cord-254419-qw83atrx	147	40	[	[	-LRB-
cord-254419-qw83atrx	147	41	29	29	CD
cord-254419-qw83atrx	147	42	]	]	-RRB-
cord-254419-qw83atrx	147	43	.	.	.
cord-254419-qw83atrx	148	1	Currently	currently	RB
cord-254419-qw83atrx	148	2	,	,	,
cord-254419-qw83atrx	148	3	there	there	EX
cord-254419-qw83atrx	148	4	are	be	VBP
cord-254419-qw83atrx	148	5	19	19	CD
cord-254419-qw83atrx	148	6	trials	trial	NNS
cord-254419-qw83atrx	148	7	registered	register	VBN
cord-254419-qw83atrx	148	8	with	with	IN
cord-254419-qw83atrx	148	9	clinicaltrials.gov	clinicaltrials.gov	NNP
cord-254419-qw83atrx	148	10	that	that	WDT
cord-254419-qw83atrx	148	11	are	be	VBP
cord-254419-qw83atrx	148	12	investigating	investigate	VBG
cord-254419-qw83atrx	148	13	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	148	14	in	in	IN
cord-254419-qw83atrx	148	15	these	these	DT
cord-254419-qw83atrx	148	16	patients	patient	NNS
cord-254419-qw83atrx	148	17	[	[	-LRB-
cord-254419-qw83atrx	148	18	52	52	CD
cord-254419-qw83atrx	148	19	]	]	-RRB-
cord-254419-qw83atrx	149	1	(	(	-LRB-
cord-254419-qw83atrx	149	2	Table	table	NN
cord-254419-qw83atrx	149	3	1	1	CD
cord-254419-qw83atrx	149	4	)	)	-RRB-
cord-254419-qw83atrx	149	5	.	.	.
cord-254419-qw83atrx	150	1	These	these	DT
cord-254419-qw83atrx	150	2	are	be	VBP
cord-254419-qw83atrx	150	3	mainly	mainly	RB
cord-254419-qw83atrx	150	4	adult	adult	NN
cord-254419-qw83atrx	150	5	trials	trial	NNS
cord-254419-qw83atrx	150	6	with	with	IN
cord-254419-qw83atrx	150	7	only	only	RB
cord-254419-qw83atrx	150	8	one	one	CD
cord-254419-qw83atrx	150	9	pediatric	pediatric	JJ
cord-254419-qw83atrx	150	10	study	study	NN
cord-254419-qw83atrx	150	11	.	.	.
cord-254419-qw83atrx	151	1	One	one	CD
cord-254419-qw83atrx	151	2	registered	registered	JJ
cord-254419-qw83atrx	151	3	study	study	NN
cord-254419-qw83atrx	151	4	aims	aim	VBZ
cord-254419-qw83atrx	151	5	to	to	TO
cord-254419-qw83atrx	151	6	look	look	VB
cord-254419-qw83atrx	151	7	at	at	IN
cord-254419-qw83atrx	151	8	antiplatelet	antiplatelet	NN
cord-254419-qw83atrx	151	9	agents	agent	NNS
cord-254419-qw83atrx	151	10	to	to	TO
cord-254419-qw83atrx	151	11	prevent	prevent	VB
cord-254419-qw83atrx	151	12	cardiac	cardiac	JJ
cord-254419-qw83atrx	151	13	complications	complication	NNS
cord-254419-qw83atrx	151	14	.	.	.
cord-254419-qw83atrx	152	1	Outcomes	outcome	NNS
cord-254419-qw83atrx	152	2	from	from	IN
cord-254419-qw83atrx	152	3	these	these	DT
cord-254419-qw83atrx	152	4	trials	trial	NNS
cord-254419-qw83atrx	152	5	(	(	-LRB-
cord-254419-qw83atrx	152	6	Table	table	NN
cord-254419-qw83atrx	152	7	1	1	CD
cord-254419-qw83atrx	152	8	)	)	-RRB-
cord-254419-qw83atrx	152	9	will	will	MD
cord-254419-qw83atrx	152	10	be	be	VB
cord-254419-qw83atrx	152	11	important	important	JJ
cord-254419-qw83atrx	152	12	for	for	IN
cord-254419-qw83atrx	152	13	our	-PRON-	PRP$
cord-254419-qw83atrx	152	14	understanding	understanding	NN
cord-254419-qw83atrx	152	15	of	of	IN
cord-254419-qw83atrx	152	16	the	the	DT
cord-254419-qw83atrx	152	17	optimum	optimum	JJ
cord-254419-qw83atrx	152	18	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	152	19	strategy	strategy	NN
cord-254419-qw83atrx	152	20	in	in	IN
cord-254419-qw83atrx	152	21	this	this	DT
cord-254419-qw83atrx	152	22	infection	infection	NN
cord-254419-qw83atrx	152	23	to	to	TO
cord-254419-qw83atrx	152	24	prevent	prevent	VB
cord-254419-qw83atrx	152	25	thrombosisassociated	thrombosisassociated	JJ
cord-254419-qw83atrx	152	26	complications	complication	NNS
cord-254419-qw83atrx	152	27	.	.	.
cord-254419-qw83atrx	153	1	Glucocorticoids	glucocorticoid	NNS
cord-254419-qw83atrx	153	2	have	have	VBP
cord-254419-qw83atrx	153	3	been	be	VBN
cord-254419-qw83atrx	153	4	investigated	investigate	VBN
cord-254419-qw83atrx	153	5	in	in	IN
cord-254419-qw83atrx	153	6	the	the	DT
cord-254419-qw83atrx	153	7	treatment	treatment	NN
cord-254419-qw83atrx	153	8	of	of	IN
cord-254419-qw83atrx	153	9	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	153	10	disease	disease	NN
cord-254419-qw83atrx	153	11	.	.	.
cord-254419-qw83atrx	154	1	Unfortunately	unfortunately	RB
cord-254419-qw83atrx	154	2	,	,	,
cord-254419-qw83atrx	154	3	the	the	DT
cord-254419-qw83atrx	154	4	first	first	JJ
cord-254419-qw83atrx	154	5	randomized	randomized	JJ
cord-254419-qw83atrx	154	6	controlled	control	VBN
cord-254419-qw83atrx	154	7	trial	trial	NN
cord-254419-qw83atrx	154	8	of	of	IN
cord-254419-qw83atrx	154	9	methylprednisolone	methylprednisolone	NN
cord-254419-qw83atrx	154	10	against	against	IN
cord-254419-qw83atrx	154	11	standard	standard	NN
cord-254419-qw83atrx	154	12	of	of	IN
cord-254419-qw83atrx	154	13	care	care	NN
cord-254419-qw83atrx	154	14	in	in	IN
cord-254419-qw83atrx	154	15	Beijing	Beijing	NNP
cord-254419-qw83atrx	154	16	,	,	,
cord-254419-qw83atrx	154	17	China	China	NNP
cord-254419-qw83atrx	154	18	(	(	-LRB-
cord-254419-qw83atrx	154	19	NCT04244591	NCT04244591	NNP
cord-254419-qw83atrx	154	20	)	)	-RRB-
cord-254419-qw83atrx	154	21	had	have	VBD
cord-254419-qw83atrx	154	22	to	to	TO
cord-254419-qw83atrx	154	23	be	be	VB
cord-254419-qw83atrx	154	24	stopped	stop	VBN
cord-254419-qw83atrx	154	25	because	because	IN
cord-254419-qw83atrx	154	26	of	of	IN
cord-254419-qw83atrx	154	27	lack	lack	NN
cord-254419-qw83atrx	154	28	of	of	IN
cord-254419-qw83atrx	154	29	patients	patient	NNS
cord-254419-qw83atrx	154	30	,	,	,
cord-254419-qw83atrx	154	31	with	with	IN
cord-254419-qw83atrx	154	32	the	the	DT
cord-254419-qw83atrx	154	33	pandemic	pandemic	NN
cord-254419-qw83atrx	154	34	ending	end	VBG
cord-254419-qw83atrx	154	35	in	in	IN
cord-254419-qw83atrx	154	36	China	China	NNP
cord-254419-qw83atrx	154	37	.	.	.
cord-254419-qw83atrx	155	1	At	at	IN
cord-254419-qw83atrx	155	2	the	the	DT
cord-254419-qw83atrx	155	3	time	time	NN
cord-254419-qw83atrx	155	4	of	of	IN
cord-254419-qw83atrx	155	5	writing	write	VBG
cord-254419-qw83atrx	155	6	this	this	DT
cord-254419-qw83atrx	155	7	review	review	NN
cord-254419-qw83atrx	155	8	,	,	,
cord-254419-qw83atrx	155	9	reports	report	NNS
cord-254419-qw83atrx	155	10	but	but	CC
cord-254419-qw83atrx	155	11	not	not	RB
cord-254419-qw83atrx	155	12	the	the	DT
cord-254419-qw83atrx	155	13	full	full	JJ
cord-254419-qw83atrx	155	14	peer	peer	NN
cord-254419-qw83atrx	155	15	-	-	HYPH
cord-254419-qw83atrx	155	16	reviewed	review	VBN
cord-254419-qw83atrx	155	17	manuscript	manuscript	NN
cord-254419-qw83atrx	155	18	for	for	IN
cord-254419-qw83atrx	155	19	the	the	DT
cord-254419-qw83atrx	155	20	Randomised	Randomised	NNP
cord-254419-qw83atrx	155	21	Evaluation	Evaluation	NNP
cord-254419-qw83atrx	155	22	of	of	IN
cord-254419-qw83atrx	155	23	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	155	24	Therapy	Therapy	NNP
cord-254419-qw83atrx	155	25	(	(	-LRB-
cord-254419-qw83atrx	155	26	RECOVERY	RECOVERY	NNP
cord-254419-qw83atrx	155	27	)	)	-RRB-
cord-254419-qw83atrx	155	28	conducted	conduct	VBN
cord-254419-qw83atrx	155	29	in	in	IN
cord-254419-qw83atrx	155	30	the	the	DT
cord-254419-qw83atrx	155	31	United	United	NNP
cord-254419-qw83atrx	155	32	Kingdom	Kingdom	NNP
cord-254419-qw83atrx	155	33	provided	provide	VBD
cord-254419-qw83atrx	155	34	preliminary	preliminary	JJ
cord-254419-qw83atrx	155	35	data	datum	NNS
cord-254419-qw83atrx	155	36	that	that	IN
cord-254419-qw83atrx	155	37	low	low	JJ
cord-254419-qw83atrx	155	38	-	-	HYPH
cord-254419-qw83atrx	155	39	dose	dose	NN
cord-254419-qw83atrx	155	40	dexamethasone	dexamethasone	NN
cord-254419-qw83atrx	155	41	reduced	reduce	VBN
cord-254419-qw83atrx	155	42	deaths	death	NNS
cord-254419-qw83atrx	155	43	by	by	IN
cord-254419-qw83atrx	155	44	one	one	CD
cord-254419-qw83atrx	155	45	-	-	HYPH
cord-254419-qw83atrx	155	46	third	third	NN
cord-254419-qw83atrx	155	47	in	in	IN
cord-254419-qw83atrx	155	48	ventilated	ventilate	VBN
cord-254419-qw83atrx	155	49	patients	patient	NNS
cord-254419-qw83atrx	155	50	and	and	CC
cord-254419-qw83atrx	155	51	by	by	IN
cord-254419-qw83atrx	155	52	onefifth	onefifth	NN
cord-254419-qw83atrx	155	53	in	in	IN
cord-254419-qw83atrx	155	54	other	other	JJ
cord-254419-qw83atrx	155	55	patients	patient	NNS
cord-254419-qw83atrx	155	56	receiving	receive	VBG
cord-254419-qw83atrx	155	57	oxygen	oxygen	NN
cord-254419-qw83atrx	155	58	,	,	,
cord-254419-qw83atrx	155	59	but	but	CC
cord-254419-qw83atrx	155	60	made	make	VBD
cord-254419-qw83atrx	155	61	no	no	DT
cord-254419-qw83atrx	155	62	difference	difference	NN
cord-254419-qw83atrx	155	63	to	to	IN
cord-254419-qw83atrx	155	64	those	those	DT
cord-254419-qw83atrx	155	65	with	with	IN
cord-254419-qw83atrx	155	66	milder	mild	JJR
cord-254419-qw83atrx	155	67	disease	disease	NN
cord-254419-qw83atrx	155	68	[	[	-LRB-
cord-254419-qw83atrx	155	69	53	53	CD
cord-254419-qw83atrx	155	70	]	]	-RRB-
cord-254419-qw83atrx	155	71	.	.	.
cord-254419-qw83atrx	156	1	There	there	EX
cord-254419-qw83atrx	156	2	are	be	VBP
cord-254419-qw83atrx	156	3	several	several	JJ
cord-254419-qw83atrx	156	4	other	other	JJ
cord-254419-qw83atrx	156	5	ongoing	ongoing	JJ
cord-254419-qw83atrx	156	6	trials	trial	NNS
cord-254419-qw83atrx	156	7	of	of	IN
cord-254419-qw83atrx	156	8	systemic	systemic	JJ
cord-254419-qw83atrx	156	9	steroids	steroid	NNS
cord-254419-qw83atrx	156	10	(	(	-LRB-
cord-254419-qw83atrx	156	11	NCT04348305	NCT04348305	NNP
cord-254419-qw83atrx	156	12	,	,	,
cord-254419-qw83atrx	156	13	NCT04360876	NCT04360876	NNP
cord-254419-qw83atrx	156	14	,	,	,
cord-254419-qw83atrx	156	15	NCT0435524	NCT0435524	NNP
cord-254419-qw83atrx	156	16	,	,	,
cord-254419-qw83atrx	156	17	NCT04323592	NCT04323592	NNP
cord-254419-qw83atrx	156	18	)	)	-RRB-
cord-254419-qw83atrx	156	19	and	and	CC
cord-254419-qw83atrx	156	20	some	some	DT
cord-254419-qw83atrx	156	21	others	other	NNS
cord-254419-qw83atrx	156	22	looking	look	VBG
cord-254419-qw83atrx	156	23	at	at	IN
cord-254419-qw83atrx	156	24	efficacy	efficacy	NN
cord-254419-qw83atrx	156	25	of	of	IN
cord-254419-qw83atrx	156	26	inhaled	inhale	VBN
cord-254419-qw83atrx	156	27	steroids	steroid	NNS
cord-254419-qw83atrx	156	28	(	(	-LRB-
cord-254419-qw83atrx	156	29	NCT04331054	NCT04331054	NNP
cord-254419-qw83atrx	156	30	,	,	,
cord-254419-qw83atrx	156	31	NCT04355637	NCT04355637	NNP
cord-254419-qw83atrx	156	32	,	,	,
cord-254419-qw83atrx	156	33	NCT04331470	NCT04331470	NNP
cord-254419-qw83atrx	156	34	)	)	-RRB-
cord-254419-qw83atrx	156	35	.	.	.
cord-254419-qw83atrx	157	1	Similar	similar	JJ
cord-254419-qw83atrx	157	2	to	to	IN
cord-254419-qw83atrx	157	3	patients	patient	NNS
cord-254419-qw83atrx	157	4	with	with	IN
cord-254419-qw83atrx	157	5	SARS	SARS	NNP
cord-254419-qw83atrx	157	6	and	and	CC
cord-254419-qw83atrx	157	7	Middle	middle	JJ
cord-254419-qw83atrx	157	8	Eastern	eastern	JJ
cord-254419-qw83atrx	157	9	Respiratory	Respiratory	NNP
cord-254419-qw83atrx	157	10	Syndrome	Syndrome	NNP
cord-254419-qw83atrx	157	11	(	(	-LRB-
cord-254419-qw83atrx	157	12	MERS	MERS	NNP
cord-254419-qw83atrx	157	13	)	)	-RRB-
cord-254419-qw83atrx	157	14	,	,	,
cord-254419-qw83atrx	157	15	the	the	DT
cord-254419-qw83atrx	157	16	cytokine	cytokine	NN
cord-254419-qw83atrx	157	17	responses	response	NNS
cord-254419-qw83atrx	157	18	seen	see	VBN
cord-254419-qw83atrx	157	19	in	in	IN
cord-254419-qw83atrx	157	20	patients	patient	NNS
cord-254419-qw83atrx	157	21	with	with	IN
cord-254419-qw83atrx	157	22	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	157	23	have	have	VBP
cord-254419-qw83atrx	157	24	features	feature	NNS
cord-254419-qw83atrx	157	25	of	of	IN
cord-254419-qw83atrx	157	26	a	a	DT
cord-254419-qw83atrx	157	27	cytokine	cytokine	NN
cord-254419-qw83atrx	157	28	storm	storm	NN
cord-254419-qw83atrx	157	29	.	.	.
cord-254419-qw83atrx	158	1	One	one	CD
cord-254419-qw83atrx	158	2	study	study	NN
cord-254419-qw83atrx	158	3	involving	involve	VBG
cord-254419-qw83atrx	158	4	43	43	CD
cord-254419-qw83atrx	158	5	adult	adult	NN
cord-254419-qw83atrx	158	6	patients	patient	NNS
cord-254419-qw83atrx	158	7	found	find	VBD
cord-254419-qw83atrx	158	8	significant	significant	JJ
cord-254419-qw83atrx	158	9	correlation	correlation	NN
cord-254419-qw83atrx	158	10	of	of	IN
cord-254419-qw83atrx	158	11	increased	increase	VBN
cord-254419-qw83atrx	158	12	baseline	baseline	JJ
cord-254419-qw83atrx	158	13	IL6	il6	NN
cord-254419-qw83atrx	158	14	levels	level	NNS
cord-254419-qw83atrx	158	15	with	with	IN
cord-254419-qw83atrx	158	16	disease	disease	NN
cord-254419-qw83atrx	158	17	severity	severity	NN
cord-254419-qw83atrx	158	18	[	[	-LRB-
cord-254419-qw83atrx	158	19	54	54	CD
cord-254419-qw83atrx	158	20	]	]	-RRB-
cord-254419-qw83atrx	158	21	and	and	CC
cord-254419-qw83atrx	158	22	this	this	DT
cord-254419-qw83atrx	158	23	is	be	VBZ
cord-254419-qw83atrx	158	24	supported	support	VBN
cord-254419-qw83atrx	158	25	by	by	IN
cord-254419-qw83atrx	158	26	similar	similar	JJ
cord-254419-qw83atrx	158	27	findings	finding	NNS
cord-254419-qw83atrx	158	28	in	in	IN
cord-254419-qw83atrx	158	29	another	another	DT
cord-254419-qw83atrx	158	30	study	study	NN
cord-254419-qw83atrx	158	31	[	[	-LRB-
cord-254419-qw83atrx	158	32	20	20	CD
cord-254419-qw83atrx	158	33	]	]	-RRB-
cord-254419-qw83atrx	158	34	.	.	.
cord-254419-qw83atrx	159	1	Hence	hence	RB
cord-254419-qw83atrx	159	2	,	,	,
cord-254419-qw83atrx	159	3	some	some	DT
cord-254419-qw83atrx	159	4	investigators	investigator	NNS
cord-254419-qw83atrx	159	5	have	have	VBP
cord-254419-qw83atrx	159	6	proposed	propose	VBN
cord-254419-qw83atrx	159	7	using	use	VBG
cord-254419-qw83atrx	159	8	IL6	IL6	NNP
cord-254419-qw83atrx	159	9	as	as	IN
cord-254419-qw83atrx	159	10	a	a	DT
cord-254419-qw83atrx	159	11	biomarker	biomarker	NN
cord-254419-qw83atrx	159	12	for	for	IN
cord-254419-qw83atrx	159	13	assessing	assess	VBG
cord-254419-qw83atrx	159	14	disease	disease	NN
cord-254419-qw83atrx	159	15	severity	severity	NN
cord-254419-qw83atrx	159	16	and	and	CC
cord-254419-qw83atrx	159	17	blocking	block	VBG
cord-254419-qw83atrx	159	18	IL6	IL6	NNP
cord-254419-qw83atrx	159	19	as	as	IN
cord-254419-qw83atrx	159	20	a	a	DT
cord-254419-qw83atrx	159	21	therapeutic	therapeutic	JJ
cord-254419-qw83atrx	159	22	strategy	strategy	NN
cord-254419-qw83atrx	159	23	has	have	VBZ
cord-254419-qw83atrx	159	24	been	be	VBN
cord-254419-qw83atrx	159	25	suggested	suggest	VBN
cord-254419-qw83atrx	159	26	[	[	-LRB-
cord-254419-qw83atrx	159	27	55	55	CD
cord-254419-qw83atrx	159	28	]	]	-RRB-
cord-254419-qw83atrx	159	29	.	.	.
cord-254419-qw83atrx	160	1	Tocilizumab	Tocilizumab	NNP
cord-254419-qw83atrx	160	2	,	,	,
cord-254419-qw83atrx	160	3	a	a	DT
cord-254419-qw83atrx	160	4	monoclonal	monoclonal	JJ
cord-254419-qw83atrx	160	5	antibody	antibody	NN
cord-254419-qw83atrx	160	6	against	against	IN
cord-254419-qw83atrx	160	7	the	the	DT
cord-254419-qw83atrx	160	8	IL6	IL6	NNP
cord-254419-qw83atrx	160	9	receptor	receptor	NN
cord-254419-qw83atrx	160	10	,	,	,
cord-254419-qw83atrx	160	11	has	have	VBZ
cord-254419-qw83atrx	160	12	been	be	VBN
cord-254419-qw83atrx	160	13	used	use	VBN
cord-254419-qw83atrx	160	14	safely	safely	RB
cord-254419-qw83atrx	160	15	and	and	CC
cord-254419-qw83atrx	160	16	effectively	effectively	RB
cord-254419-qw83atrx	160	17	in	in	IN
cord-254419-qw83atrx	160	18	patients	patient	NNS
cord-254419-qw83atrx	160	19	with	with	IN
cord-254419-qw83atrx	160	20	rheumatoid	rheumatoid	NN
cord-254419-qw83atrx	160	21	arthritis	arthritis	NN
cord-254419-qw83atrx	160	22	[	[	-LRB-
cord-254419-qw83atrx	160	23	56	56	CD
cord-254419-qw83atrx	160	24	]	]	-RRB-
cord-254419-qw83atrx	160	25	.	.	.
cord-254419-qw83atrx	161	1	A	a	DT
cord-254419-qw83atrx	161	2	pilot	pilot	NN
cord-254419-qw83atrx	161	3	trial	trial	NN
cord-254419-qw83atrx	161	4	of	of	IN
cord-254419-qw83atrx	161	5	adding	add	VBG
cord-254419-qw83atrx	161	6	tocilizumab	tocilizumab	JJ
cord-254419-qw83atrx	161	7	therapy	therapy	NN
cord-254419-qw83atrx	161	8	in	in	IN
cord-254419-qw83atrx	161	9	patients	patient	NNS
cord-254419-qw83atrx	161	10	with	with	IN
cord-254419-qw83atrx	161	11	severe	severe	JJ
cord-254419-qw83atrx	161	12	COVID-19	covid-19	JJ
cord-254419-qw83atrx	161	13	disease	disease	NN
cord-254419-qw83atrx	161	14	in	in	IN
cord-254419-qw83atrx	161	15	combination	combination	NN
cord-254419-qw83atrx	161	16	with	with	IN
cord-254419-qw83atrx	161	17	standard	standard	JJ
cord-254419-qw83atrx	161	18	therapy	therapy	NN
cord-254419-qw83atrx	161	19	of	of	IN
cord-254419-qw83atrx	161	20	lopinavir	lopinavir	NNP
cord-254419-qw83atrx	161	21	,	,	,
cord-254419-qw83atrx	161	22	methylprednisolone	methylprednisolone	NNP
cord-254419-qw83atrx	161	23	,	,	,
cord-254419-qw83atrx	161	24	and	and	CC
cord-254419-qw83atrx	161	25	oxygen	oxygen	NN
cord-254419-qw83atrx	161	26	therapy	therapy	NN
cord-254419-qw83atrx	161	27	showed	show	VBD
cord-254419-qw83atrx	161	28	remarkable	remarkable	JJ
cord-254419-qw83atrx	161	29	short	short	JJ
cord-254419-qw83atrx	161	30	-	-	HYPH
cord-254419-qw83atrx	161	31	term	term	NN
cord-254419-qw83atrx	161	32	clinical	clinical	JJ
cord-254419-qw83atrx	161	33	responses	response	NNS
cord-254419-qw83atrx	161	34	in	in	IN
cord-254419-qw83atrx	161	35	20	20	CD
cord-254419-qw83atrx	161	36	out	out	IN
cord-254419-qw83atrx	161	37	of	of	IN
cord-254419-qw83atrx	161	38	21	21	CD
cord-254419-qw83atrx	161	39	patients	patient	NNS
cord-254419-qw83atrx	161	40	within	within	IN
cord-254419-qw83atrx	161	41	2	2	CD
cord-254419-qw83atrx	161	42	weeks	week	NNS
cord-254419-qw83atrx	161	43	of	of	IN
cord-254419-qw83atrx	161	44	tocilizumab	tocilizumab	NN
cord-254419-qw83atrx	161	45	therapy	therapy	NN
cord-254419-qw83atrx	161	46	[	[	-LRB-
cord-254419-qw83atrx	161	47	57	57	CD
cord-254419-qw83atrx	161	48	]	]	-RRB-
cord-254419-qw83atrx	161	49	.	.	.
cord-254419-qw83atrx	162	1	No	no	DT
cord-254419-qw83atrx	162	2	adverse	adverse	JJ
cord-254419-qw83atrx	162	3	drug	drug	NN
cord-254419-qw83atrx	162	4	reactions	reaction	NNS
cord-254419-qw83atrx	162	5	attributable	attributable	JJ
cord-254419-qw83atrx	162	6	to	to	IN
cord-254419-qw83atrx	162	7	tocilizumab	tocilizumab	NNP
cord-254419-qw83atrx	162	8	were	be	VBD
cord-254419-qw83atrx	162	9	noted	note	VBN
cord-254419-qw83atrx	162	10	.	.	.
cord-254419-qw83atrx	163	1	Following	follow	VBG
cord-254419-qw83atrx	163	2	the	the	DT
cord-254419-qw83atrx	163	3	success	success	NN
cord-254419-qw83atrx	163	4	of	of	IN
cord-254419-qw83atrx	163	5	this	this	DT
cord-254419-qw83atrx	163	6	preliminary	preliminary	JJ
cord-254419-qw83atrx	163	7	trial	trial	NN
cord-254419-qw83atrx	163	8	,	,	,
cord-254419-qw83atrx	163	9	a	a	DT
cord-254419-qw83atrx	163	10	larger	large	JJR
cord-254419-qw83atrx	163	11	multicenter	multicenter	JJ
cord-254419-qw83atrx	163	12	clinical	clinical	JJ
cord-254419-qw83atrx	163	13	trial	trial	NN
cord-254419-qw83atrx	163	14	is	be	VBZ
cord-254419-qw83atrx	163	15	currently	currently	RB
cord-254419-qw83atrx	163	16	being	be	VBG
cord-254419-qw83atrx	163	17	undertaken	undertake	VBN
cord-254419-qw83atrx	163	18	(	(	-LRB-
cord-254419-qw83atrx	163	19	ChiCTR2000029765	ChiCTR2000029765	VBN
cord-254419-qw83atrx	163	20	)	)	-RRB-
cord-254419-qw83atrx	163	21	.	.	.
cord-254419-qw83atrx	164	1	Another	another	DT
cord-254419-qw83atrx	164	2	trial	trial	NN
cord-254419-qw83atrx	164	3	in	in	IN
cord-254419-qw83atrx	164	4	Belgium	Belgium	NNP
cord-254419-qw83atrx	164	5	has	have	VBZ
cord-254419-qw83atrx	164	6	been	be	VBN
cord-254419-qw83atrx	164	7	designed	design	VBN
cord-254419-qw83atrx	164	8	to	to	TO
cord-254419-qw83atrx	164	9	observe	observe	VB
cord-254419-qw83atrx	164	10	the	the	DT
cord-254419-qw83atrx	164	11	efficacy	efficacy	NN
cord-254419-qw83atrx	164	12	of	of	IN
cord-254419-qw83atrx	164	13	the	the	DT
cord-254419-qw83atrx	164	14	IL6	IL6	NNP
cord-254419-qw83atrx	164	15	blockers	blocker	NNS
cord-254419-qw83atrx	164	16	tocilizumab	tocilizumab	NNP
cord-254419-qw83atrx	164	17	and	and	CC
cord-254419-qw83atrx	164	18	siltuximab	siltuximab	NNP
cord-254419-qw83atrx	164	19	individually	individually	RB
cord-254419-qw83atrx	164	20	and	and	CC
cord-254419-qw83atrx	164	21	in	in	IN
cord-254419-qw83atrx	164	22	combination	combination	NN
cord-254419-qw83atrx	164	23	with	with	IN
cord-254419-qw83atrx	164	24	the	the	DT
cord-254419-qw83atrx	164	25	IL1	IL1	NNP
cord-254419-qw83atrx	164	26	blocker	blocker	NN
cord-254419-qw83atrx	164	27	anakinra	anakinra	NNP
cord-254419-qw83atrx	164	28	(	(	-LRB-
cord-254419-qw83atrx	164	29	NCT04330638	NCT04330638	NNP
cord-254419-qw83atrx	164	30	)	)	-RRB-
cord-254419-qw83atrx	164	31	.	.	.
cord-254419-qw83atrx	165	1	Indeed	indeed	RB
cord-254419-qw83atrx	165	2	,	,	,
cord-254419-qw83atrx	165	3	IL1	IL1	NNP
cord-254419-qw83atrx	165	4	,	,	,
cord-254419-qw83atrx	165	5	IL18	IL18	NNP
cord-254419-qw83atrx	165	6	blockade	blockade	NN
cord-254419-qw83atrx	165	7	,	,	,
cord-254419-qw83atrx	165	8	IFN	IFN	NNP
cord-254419-qw83atrx	165	9	-	-	HYPH
cord-254419-qw83atrx	165	10	c	c	NNP
cord-254419-qw83atrx	165	11	inhibition	inhibition	NN
cord-254419-qw83atrx	165	12	,	,	,
cord-254419-qw83atrx	165	13	and	and	CC
cord-254419-qw83atrx	165	14	TNFa	TNFa	NNP
cord-254419-qw83atrx	165	15	inhibition	inhibition	NN
cord-254419-qw83atrx	165	16	are	be	VBP
cord-254419-qw83atrx	165	17	also	also	RB
cord-254419-qw83atrx	165	18	amongst	amongst	IN
cord-254419-qw83atrx	165	19	consideration	consideration	NN
cord-254419-qw83atrx	165	20	for	for	IN
cord-254419-qw83atrx	165	21	randomized	randomized	JJ
cord-254419-qw83atrx	165	22	control	control	NN
cord-254419-qw83atrx	165	23	trials	trial	NNS
cord-254419-qw83atrx	165	24	in	in	IN
cord-254419-qw83atrx	165	25	patients	patient	NNS
cord-254419-qw83atrx	165	26	with	with	IN
cord-254419-qw83atrx	165	27	severe	severe	JJ
cord-254419-qw83atrx	165	28	disease	disease	NN
cord-254419-qw83atrx	165	29	.	.	.
cord-254419-qw83atrx	166	1	High	high	JJ
cord-254419-qw83atrx	166	2	-	-	HYPH
cord-254419-qw83atrx	166	3	dose	dose	NN
cord-254419-qw83atrx	166	4	intravenous	intravenous	JJ
cord-254419-qw83atrx	166	5	immunoglobulin	immunoglobulin	NN
cord-254419-qw83atrx	166	6	(	(	-LRB-
cord-254419-qw83atrx	166	7	IVIG	IVIG	NNP
cord-254419-qw83atrx	166	8	)	)	-RRB-
cord-254419-qw83atrx	166	9	has	have	VBZ
cord-254419-qw83atrx	166	10	been	be	VBN
cord-254419-qw83atrx	166	11	used	use	VBN
cord-254419-qw83atrx	166	12	as	as	IN
cord-254419-qw83atrx	166	13	an	an	DT
cord-254419-qw83atrx	166	14	immunomodulator	immunomodulator	NN
cord-254419-qw83atrx	166	15	in	in	IN
cord-254419-qw83atrx	166	16	patients	patient	NNS
cord-254419-qw83atrx	166	17	with	with	IN
cord-254419-qw83atrx	166	18	severe	severe	JJ
cord-254419-qw83atrx	166	19	disease	disease	NN
cord-254419-qw83atrx	166	20	with	with	IN
cord-254419-qw83atrx	166	21	good	good	JJ
cord-254419-qw83atrx	166	22	outcomes	outcome	NNS
cord-254419-qw83atrx	166	23	[	[	-LRB-
cord-254419-qw83atrx	166	24	58	58	CD
cord-254419-qw83atrx	166	25	]	]	-RRB-
cord-254419-qw83atrx	166	26	.	.	.
cord-254419-qw83atrx	167	1	There	there	EX
cord-254419-qw83atrx	167	2	are	be	VBP
cord-254419-qw83atrx	167	3	several	several	JJ
cord-254419-qw83atrx	167	4	trials	trial	NNS
cord-254419-qw83atrx	167	5	currently	currently	RB
cord-254419-qw83atrx	167	6	exploring	explore	VBG
cord-254419-qw83atrx	167	7	the	the	DT
cord-254419-qw83atrx	167	8	utility	utility	NN
cord-254419-qw83atrx	167	9	of	of	IN
cord-254419-qw83atrx	167	10	IVIG	IVIG	NNP
cord-254419-qw83atrx	167	11	(	(	-LRB-
cord-254419-qw83atrx	167	12	NCT04411667	NCT04411667	NNP
cord-254419-qw83atrx	167	13	,	,	,
cord-254419-qw83atrx	167	14	NCT04400058	NCT04400058	NNP
cord-254419-qw83atrx	167	15	,	,	,
cord-254419-qw83atrx	167	16	NCT04261426	NCT04261426	NNP
cord-254419-qw83atrx	167	17	,	,	,
cord-254419-qw83atrx	167	18	NCT04403269	NCT04403269	NNP
cord-254419-qw83atrx	167	19	,	,	,
cord-254419-qw83atrx	167	20	and	and	CC
cord-254419-qw83atrx	167	21	NCT04350580	NCT04350580	NNP
cord-254419-qw83atrx	167	22	)	)	-RRB-
cord-254419-qw83atrx	167	23	.	.	.
cord-254419-qw83atrx	168	1	The	the	DT
cord-254419-qw83atrx	168	2	role	role	NN
cord-254419-qw83atrx	168	3	of	of	IN
cord-254419-qw83atrx	168	4	non	non	JJ
cord-254419-qw83atrx	168	5	-	-	JJ
cord-254419-qw83atrx	168	6	steroidal	steroidal	JJ
cord-254419-qw83atrx	168	7	anti	anti	JJ
cord-254419-qw83atrx	168	8	-	-	JJ
cord-254419-qw83atrx	168	9	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	168	10	drugs	drug	NNS
cord-254419-qw83atrx	168	11	(	(	-LRB-
cord-254419-qw83atrx	168	12	NSAIDS	NSAIDS	NNP
cord-254419-qw83atrx	168	13	)	)	-RRB-
cord-254419-qw83atrx	168	14	as	as	IN
cord-254419-qw83atrx	168	15	therapy	therapy	NN
cord-254419-qw83atrx	168	16	is	be	VBZ
cord-254419-qw83atrx	168	17	extremely	extremely	RB
cord-254419-qw83atrx	168	18	controversial	controversial	JJ
cord-254419-qw83atrx	168	19	.	.	.
cord-254419-qw83atrx	169	1	Ibuprofen	ibuprofen	NN
cord-254419-qw83atrx	169	2	is	be	VBZ
cord-254419-qw83atrx	169	3	a	a	DT
cord-254419-qw83atrx	169	4	commonly	commonly	RB
cord-254419-qw83atrx	169	5	used	use	VBN
cord-254419-qw83atrx	169	6	NSAID	NSAID	NNP
cord-254419-qw83atrx	169	7	,	,	,
cord-254419-qw83atrx	169	8	which	which	WDT
cord-254419-qw83atrx	169	9	is	be	VBZ
cord-254419-qw83atrx	169	10	used	use	VBN
cord-254419-qw83atrx	169	11	for	for	IN
cord-254419-qw83atrx	169	12	fever	fever	NN
cord-254419-qw83atrx	169	13	control	control	NN
cord-254419-qw83atrx	169	14	,	,	,
cord-254419-qw83atrx	169	15	usually	usually	RB
cord-254419-qw83atrx	169	16	with	with	IN
cord-254419-qw83atrx	169	17	acetaminophen	acetaminophen	NN
cord-254419-qw83atrx	169	18	.	.	.
cord-254419-qw83atrx	170	1	However	however	RB
cord-254419-qw83atrx	170	2	,	,	,
cord-254419-qw83atrx	170	3	ibuprofen	ibuprofen	NN
cord-254419-qw83atrx	170	4	increases	increase	VBZ
cord-254419-qw83atrx	170	5	the	the	DT
cord-254419-qw83atrx	170	6	synthesis	synthesis	NN
cord-254419-qw83atrx	170	7	of	of	IN
cord-254419-qw83atrx	170	8	ACE2	ACE2	NNP
cord-254419-qw83atrx	170	9	enzyme	enzyme	NN
cord-254419-qw83atrx	170	10	and	and	CC
cord-254419-qw83atrx	170	11	may	may	MD
cord-254419-qw83atrx	170	12	potentially	potentially	RB
cord-254419-qw83atrx	170	13	increase	increase	VB
cord-254419-qw83atrx	170	14	the	the	DT
cord-254419-qw83atrx	170	15	risk	risk	NN
cord-254419-qw83atrx	170	16	of	of	IN
cord-254419-qw83atrx	170	17	severity	severity	NN
cord-254419-qw83atrx	170	18	and	and	CC
cord-254419-qw83atrx	170	19	fatality	fatality	NN
cord-254419-qw83atrx	170	20	of	of	IN
cord-254419-qw83atrx	170	21	COVID	COVID	NNP
cord-254419-qw83atrx	170	22	19	19	CD
cord-254419-qw83atrx	170	23	infection	infection	NN
cord-254419-qw83atrx	170	24	[	[	-LRB-
cord-254419-qw83atrx	170	25	59	59	CD
cord-254419-qw83atrx	170	26	]	]	-RRB-
cord-254419-qw83atrx	170	27	.	.	.
cord-254419-qw83atrx	171	1	However	however	RB
cord-254419-qw83atrx	171	2	,	,	,
cord-254419-qw83atrx	171	3	currently	currently	RB
cord-254419-qw83atrx	171	4	there	there	EX
cord-254419-qw83atrx	171	5	is	be	VBZ
cord-254419-qw83atrx	171	6	no	no	DT
cord-254419-qw83atrx	171	7	definite	definite	JJ
cord-254419-qw83atrx	171	8	evidence	evidence	NN
cord-254419-qw83atrx	171	9	for	for	IN
cord-254419-qw83atrx	171	10	or	or	CC
cord-254419-qw83atrx	171	11	against	against	IN
cord-254419-qw83atrx	171	12	the	the	DT
cord-254419-qw83atrx	171	13	use	use	NN
cord-254419-qw83atrx	171	14	of	of	IN
cord-254419-qw83atrx	171	15	ibuprofen	ibuprofen	NN
cord-254419-qw83atrx	171	16	.	.	.
cord-254419-qw83atrx	172	1	The	the	DT
cord-254419-qw83atrx	172	2	European	European	NNP
cord-254419-qw83atrx	172	3	Medicine	Medicine	NNP
cord-254419-qw83atrx	172	4	Agency	Agency	NNP
cord-254419-qw83atrx	172	5	(	(	-LRB-
cord-254419-qw83atrx	172	6	EMA	EMA	NNP
cord-254419-qw83atrx	172	7	)	)	-RRB-
cord-254419-qw83atrx	172	8	guidelines	guideline	NNS
cord-254419-qw83atrx	172	9	published	publish	VBN
cord-254419-qw83atrx	172	10	on	on	IN
cord-254419-qw83atrx	172	11	March	March	NNP
cord-254419-qw83atrx	172	12	31	31	CD
cord-254419-qw83atrx	172	13	,	,	,
cord-254419-qw83atrx	172	14	2020	2020	CD
cord-254419-qw83atrx	172	15	suggest	suggest	VBP
cord-254419-qw83atrx	172	16	using	use	VBG
cord-254419-qw83atrx	172	17	acetaminophen	acetaminophen	NN
cord-254419-qw83atrx	172	18	for	for	IN
cord-254419-qw83atrx	172	19	fever	fever	NN
cord-254419-qw83atrx	172	20	but	but	CC
cord-254419-qw83atrx	172	21	also	also	RB
cord-254419-qw83atrx	172	22	had	have	VBD
cord-254419-qw83atrx	172	23	advised	advise	VBN
cord-254419-qw83atrx	172	24	not	not	RB
cord-254419-qw83atrx	172	25	to	to	TO
cord-254419-qw83atrx	172	26	stop	stop	VB
cord-254419-qw83atrx	172	27	ibuprofen	ibuprofen	NN
cord-254419-qw83atrx	172	28	if	if	IN
cord-254419-qw83atrx	172	29	the	the	DT
cord-254419-qw83atrx	172	30	patient	patient	NN
cord-254419-qw83atrx	172	31	is	be	VBZ
cord-254419-qw83atrx	172	32	on	on	IN
cord-254419-qw83atrx	172	33	it	-PRON-	PRP
cord-254419-qw83atrx	172	34	for	for	IN
cord-254419-qw83atrx	172	35	other	other	JJ
cord-254419-qw83atrx	172	36	reasons	reason	NNS
cord-254419-qw83atrx	172	37	[	[	-LRB-
cord-254419-qw83atrx	172	38	60	60	CD
cord-254419-qw83atrx	172	39	]	]	-RRB-
cord-254419-qw83atrx	172	40	.	.	.
cord-254419-qw83atrx	173	1	Currently	currently	RB
cord-254419-qw83atrx	173	2	,	,	,
cord-254419-qw83atrx	173	3	there	there	EX
cord-254419-qw83atrx	173	4	are	be	VBP
cord-254419-qw83atrx	173	5	ongoing	ongoing	JJ
cord-254419-qw83atrx	173	6	trials	trial	NNS
cord-254419-qw83atrx	173	7	to	to	TO
cord-254419-qw83atrx	173	8	assess	assess	VB
cord-254419-qw83atrx	173	9	the	the	DT
cord-254419-qw83atrx	173	10	efficacy	efficacy	NN
cord-254419-qw83atrx	173	11	of	of	IN
cord-254419-qw83atrx	173	12	inhaled	inhale	VBN
cord-254419-qw83atrx	173	13	ibuprofen	ibuprofen	NNP
cord-254419-qw83atrx	173	14	(	(	-LRB-
cord-254419-qw83atrx	173	15	NCT04382768	NCT04382768	NNP
cord-254419-qw83atrx	173	16	)	)	-RRB-
cord-254419-qw83atrx	173	17	and	and	CC
cord-254419-qw83atrx	173	18	also	also	RB
cord-254419-qw83atrx	173	19	oral	oral	JJ
cord-254419-qw83atrx	173	20	lipid	lipid	NN
cord-254419-qw83atrx	173	21	formulation	formulation	NN
cord-254419-qw83atrx	173	22	of	of	IN
cord-254419-qw83atrx	173	23	ibuprofen	ibuprofen	NN
cord-254419-qw83atrx	173	24	(	(	-LRB-
cord-254419-qw83atrx	173	25	LIBERATE	liberate	VB
cord-254419-qw83atrx	173	26	trial	trial	NN
cord-254419-qw83atrx	173	27	,	,	,
cord-254419-qw83atrx	173	28	Lipid	Lipid	NNP
cord-254419-qw83atrx	173	29	ibuprofen	ibuprofen	NN
cord-254419-qw83atrx	173	30	versus	versus	IN
cord-254419-qw83atrx	173	31	standard	standard	NN
cord-254419-qw83atrx	173	32	of	of	IN
cord-254419-qw83atrx	173	33	care	care	NN
cord-254419-qw83atrx	173	34	for	for	IN
cord-254419-qw83atrx	173	35	acute	acute	JJ
cord-254419-qw83atrx	173	36	hypoxemic	hypoxemic	JJ
cord-254419-qw83atrx	173	37	respiratory	respiratory	JJ
cord-254419-qw83atrx	173	38	failure	failure	NN
cord-254419-qw83atrx	173	39	due	due	JJ
cord-254419-qw83atrx	173	40	to	to	IN
cord-254419-qw83atrx	173	41	COVID19	COVID19	NNP
cord-254419-qw83atrx	173	42	,	,	,
cord-254419-qw83atrx	173	43	NCT04334629	NCT04334629	NNP
cord-254419-qw83atrx	173	44	)	)	-RRB-
cord-254419-qw83atrx	173	45	.	.	.
cord-254419-qw83atrx	174	1	The	the	DT
cord-254419-qw83atrx	174	2	efficacy	efficacy	NN
cord-254419-qw83atrx	174	3	and	and	CC
cord-254419-qw83atrx	174	4	safety	safety	NN
cord-254419-qw83atrx	174	5	of	of	IN
cord-254419-qw83atrx	174	6	other	other	JJ
cord-254419-qw83atrx	174	7	NSAIDS	NSAIDS	NNP
cord-254419-qw83atrx	174	8	are	be	VBP
cord-254419-qw83atrx	174	9	currently	currently	RB
cord-254419-qw83atrx	174	10	being	be	VBG
cord-254419-qw83atrx	174	11	evaluated	evaluate	VBN
cord-254419-qw83atrx	174	12	,	,	,
cord-254419-qw83atrx	174	13	the	the	DT
cord-254419-qw83atrx	174	14	details	detail	NNS
cord-254419-qw83atrx	174	15	of	of	IN
cord-254419-qw83atrx	174	16	which	which	WDT
cord-254419-qw83atrx	174	17	are	be	VBP
cord-254419-qw83atrx	174	18	beyond	beyond	IN
cord-254419-qw83atrx	174	19	the	the	DT
cord-254419-qw83atrx	174	20	scope	scope	NN
cord-254419-qw83atrx	174	21	of	of	IN
cord-254419-qw83atrx	174	22	this	this	DT
cord-254419-qw83atrx	174	23	article	article	NN
cord-254419-qw83atrx	174	24	.	.	.
cord-254419-qw83atrx	175	1	Combining	combine	VBG
cord-254419-qw83atrx	175	2	anti	anti	JJ
cord-254419-qw83atrx	175	3	-	-	JJ
cord-254419-qw83atrx	175	4	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	175	5	agents	agent	NNS
cord-254419-qw83atrx	175	6	with	with	IN
cord-254419-qw83atrx	175	7	anti	anti	JJ
cord-254419-qw83atrx	175	8	-	-	JJ
cord-254419-qw83atrx	175	9	viral	viral	JJ
cord-254419-qw83atrx	175	10	agents	agent	NNS
cord-254419-qw83atrx	175	11	is	be	VBZ
cord-254419-qw83atrx	175	12	another	another	DT
cord-254419-qw83atrx	175	13	attractive	attractive	JJ
cord-254419-qw83atrx	175	14	option	option	NN
cord-254419-qw83atrx	175	15	.	.	.
cord-254419-qw83atrx	176	1	Artificial	artificial	JJ
cord-254419-qw83atrx	176	2	intelligence	intelligence	NN
cord-254419-qw83atrx	176	3	(	(	-LRB-
cord-254419-qw83atrx	176	4	AI)-powered	ai)-powered	CD
cord-254419-qw83atrx	176	5	algorithm	algorithm	NN
cord-254419-qw83atrx	176	6	predictions	prediction	NNS
cord-254419-qw83atrx	176	7	have	have	VBP
cord-254419-qw83atrx	176	8	identified	identify	VBN
cord-254419-qw83atrx	176	9	baricitinib	baricitinib	NN
cord-254419-qw83atrx	176	10	,	,	,
cord-254419-qw83atrx	176	11	ruxolitinib	ruxolitinib	JJ
cord-254419-qw83atrx	176	12	,	,	,
cord-254419-qw83atrx	176	13	and	and	CC
cord-254419-qw83atrx	176	14	fedratinib	fedratinib	NN
cord-254419-qw83atrx	176	15	as	as	IN
cord-254419-qw83atrx	176	16	potential	potential	JJ
cord-254419-qw83atrx	176	17	candidates	candidate	NNS
cord-254419-qw83atrx	176	18	[	[	-LRB-
cord-254419-qw83atrx	176	19	61	61	CD
cord-254419-qw83atrx	176	20	]	]	-RRB-
cord-254419-qw83atrx	176	21	.	.	.
cord-254419-qw83atrx	177	1	These	these	DT
cord-254419-qw83atrx	177	2	drugs	drug	NNS
cord-254419-qw83atrx	177	3	belong	belong	VBP
cord-254419-qw83atrx	177	4	to	to	IN
cord-254419-qw83atrx	177	5	the	the	DT
cord-254419-qw83atrx	177	6	Janus	Janus	NNP
cord-254419-qw83atrx	177	7	kinase	kinase	NN
cord-254419-qw83atrx	177	8	(	(	-LRB-
cord-254419-qw83atrx	177	9	JAK	JAK	NNP
cord-254419-qw83atrx	177	10	)	)	-RRB-
cord-254419-qw83atrx	177	11	inhibitor	inhibitor	NN
cord-254419-qw83atrx	177	12	class	class	NN
cord-254419-qw83atrx	177	13	of	of	IN
cord-254419-qw83atrx	177	14	medications	medication	NNS
cord-254419-qw83atrx	177	15	that	that	WDT
cord-254419-qw83atrx	177	16	have	have	VBP
cord-254419-qw83atrx	177	17	been	be	VBN
cord-254419-qw83atrx	177	18	approved	approve	VBN
cord-254419-qw83atrx	177	19	and	and	CC
cord-254419-qw83atrx	177	20	used	use	VBN
cord-254419-qw83atrx	177	21	safely	safely	RB
cord-254419-qw83atrx	177	22	in	in	IN
cord-254419-qw83atrx	177	23	conditions	condition	NNS
cord-254419-qw83atrx	177	24	like	like	IN
cord-254419-qw83atrx	177	25	myelofibrosis	myelofibrosis	NNP
cord-254419-qw83atrx	177	26	and	and	CC
cord-254419-qw83atrx	177	27	rheumatoid	rheumatoid	NNP
cord-254419-qw83atrx	177	28	arthritis	arthritis	NN
cord-254419-qw83atrx	177	29	.	.	.
cord-254419-qw83atrx	178	1	These	these	DT
cord-254419-qw83atrx	178	2	drugs	drug	NNS
cord-254419-qw83atrx	178	3	are	be	VBP
cord-254419-qw83atrx	178	4	powerful	powerful	JJ
cord-254419-qw83atrx	178	5	anti	anti	JJ
cord-254419-qw83atrx	178	6	-	-	JJ
cord-254419-qw83atrx	178	7	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	178	8	agents	agent	NNS
cord-254419-qw83atrx	178	9	that	that	WDT
cord-254419-qw83atrx	178	10	target	target	VBP
cord-254419-qw83atrx	178	11	the	the	DT
cord-254419-qw83atrx	178	12	JAK	JAK	NNP
cord-254419-qw83atrx	178	13	-	-	HYPH
cord-254419-qw83atrx	178	14	STAT	stat	NN
cord-254419-qw83atrx	178	15	pathways	pathway	NNS
cord-254419-qw83atrx	178	16	and	and	CC
cord-254419-qw83atrx	178	17	are	be	VBP
cord-254419-qw83atrx	178	18	likely	likely	JJ
cord-254419-qw83atrx	178	19	to	to	TO
cord-254419-qw83atrx	178	20	be	be	VB
cord-254419-qw83atrx	178	21	effective	effective	JJ
cord-254419-qw83atrx	178	22	against	against	IN
cord-254419-qw83atrx	178	23	the	the	DT
cord-254419-qw83atrx	178	24	deleterious	deleterious	JJ
cord-254419-qw83atrx	178	25	consequences	consequence	NNS
cord-254419-qw83atrx	178	26	of	of	IN
cord-254419-qw83atrx	178	27	elevated	elevated	JJ
cord-254419-qw83atrx	178	28	cytokines	cytokine	NNS
cord-254419-qw83atrx	178	29	.	.	.
cord-254419-qw83atrx	179	1	Of	of	IN
cord-254419-qw83atrx	179	2	particular	particular	JJ
cord-254419-qw83atrx	179	3	interest	interest	NN
cord-254419-qw83atrx	179	4	is	be	VBZ
cord-254419-qw83atrx	179	5	baricitinib	baricitinib	NNP
cord-254419-qw83atrx	179	6	,	,	,
cord-254419-qw83atrx	179	7	which	which	WDT
cord-254419-qw83atrx	179	8	is	be	VBZ
cord-254419-qw83atrx	179	9	predicted	predict	VBN
cord-254419-qw83atrx	179	10	to	to	TO
cord-254419-qw83atrx	179	11	interfere	interfere	VB
cord-254419-qw83atrx	179	12	with	with	IN
cord-254419-qw83atrx	179	13	the	the	DT
cord-254419-qw83atrx	179	14	ability	ability	NN
cord-254419-qw83atrx	179	15	of	of	IN
cord-254419-qw83atrx	179	16	the	the	DT
cord-254419-qw83atrx	179	17	virus	virus	NN
cord-254419-qw83atrx	179	18	to	to	TO
cord-254419-qw83atrx	179	19	enter	enter	VB
cord-254419-qw83atrx	179	20	and	and	CC
cord-254419-qw83atrx	179	21	infect	infect	VB
cord-254419-qw83atrx	179	22	lung	lung	NN
cord-254419-qw83atrx	179	23	cells	cell	NNS
cord-254419-qw83atrx	179	24	by	by	IN
cord-254419-qw83atrx	179	25	receptor	receptor	NN
cord-254419-qw83atrx	179	26	-	-	HYPH
cord-254419-qw83atrx	179	27	mediated	mediate	VBN
cord-254419-qw83atrx	179	28	endocytosis	endocytosis	NN
cord-254419-qw83atrx	179	29	[	[	-LRB-
cord-254419-qw83atrx	179	30	62	62	CD
cord-254419-qw83atrx	179	31	]	]	-RRB-
cord-254419-qw83atrx	179	32	.	.	.
cord-254419-qw83atrx	180	1	Due	due	IN
cord-254419-qw83atrx	180	2	to	to	IN
cord-254419-qw83atrx	180	3	the	the	DT
cord-254419-qw83atrx	180	4	favorable	favorable	JJ
cord-254419-qw83atrx	180	5	pharmacological	pharmacological	JJ
cord-254419-qw83atrx	180	6	and	and	CC
cord-254419-qw83atrx	180	7	safety	safety	NN
cord-254419-qw83atrx	180	8	profile	profile	NN
cord-254419-qw83atrx	180	9	of	of	IN
cord-254419-qw83atrx	180	10	baricitinib	baricitinib	NNP
cord-254419-qw83atrx	180	11	,	,	,
cord-254419-qw83atrx	180	12	it	-PRON-	PRP
cord-254419-qw83atrx	180	13	can	can	MD
cord-254419-qw83atrx	180	14	be	be	VB
cord-254419-qw83atrx	180	15	considered	consider	VBN
cord-254419-qw83atrx	180	16	in	in	IN
cord-254419-qw83atrx	180	17	combination	combination	NN
cord-254419-qw83atrx	180	18	with	with	IN
cord-254419-qw83atrx	180	19	direct	direct	JJ
cord-254419-qw83atrx	180	20	-	-	HYPH
cord-254419-qw83atrx	180	21	acting	act	VBG
cord-254419-qw83atrx	180	22	anti	anti	JJ
cord-254419-qw83atrx	180	23	-	-	JJ
cord-254419-qw83atrx	180	24	viral	viral	JJ
cord-254419-qw83atrx	180	25	agents	agent	NNS
cord-254419-qw83atrx	180	26	like	like	IN
cord-254419-qw83atrx	180	27	lopinavir	lopinavir	NNS
cord-254419-qw83atrx	180	28	,	,	,
cord-254419-qw83atrx	180	29	remdesivir	remdesivir	NNP
cord-254419-qw83atrx	180	30	,	,	,
cord-254419-qw83atrx	180	31	and	and	CC
cord-254419-qw83atrx	180	32	ritonavir	ritonavir	NNP
cord-254419-qw83atrx	180	33	to	to	TO
cord-254419-qw83atrx	180	34	decrease	decrease	VB
cord-254419-qw83atrx	180	35	the	the	DT
cord-254419-qw83atrx	180	36	viral	viral	JJ
cord-254419-qw83atrx	180	37	replication	replication	NN
cord-254419-qw83atrx	180	38	,	,	,
cord-254419-qw83atrx	180	39	infectivity	infectivity	NN
cord-254419-qw83atrx	180	40	,	,	,
cord-254419-qw83atrx	180	41	as	as	RB
cord-254419-qw83atrx	180	42	well	well	RB
cord-254419-qw83atrx	180	43	as	as	IN
cord-254419-qw83atrx	180	44	to	to	TO
cord-254419-qw83atrx	180	45	calm	calm	VB
cord-254419-qw83atrx	180	46	the	the	DT
cord-254419-qw83atrx	180	47	cytokine	cytokine	NN
cord-254419-qw83atrx	180	48	responses	response	NNS
cord-254419-qw83atrx	180	49	.	.	.
cord-254419-qw83atrx	181	1	Statins	statin	NNS
cord-254419-qw83atrx	181	2	,	,	,
cord-254419-qw83atrx	181	3	another	another	DT
cord-254419-qw83atrx	181	4	group	group	NN
cord-254419-qw83atrx	181	5	of	of	IN
cord-254419-qw83atrx	181	6	drugs	drug	NNS
cord-254419-qw83atrx	181	7	that	that	WDT
cord-254419-qw83atrx	181	8	have	have	VBP
cord-254419-qw83atrx	181	9	anti	anti	JJ
cord-254419-qw83atrx	181	10	-	-	JJ
cord-254419-qw83atrx	181	11	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	181	12	and	and	CC
cord-254419-qw83atrx	181	13	antithrombotic	antithrombotic	JJ
cord-254419-qw83atrx	181	14	properties	property	NNS
cord-254419-qw83atrx	181	15	,	,	,
cord-254419-qw83atrx	181	16	have	have	VBP
cord-254419-qw83atrx	181	17	also	also	RB
cord-254419-qw83atrx	181	18	been	be	VBN
cord-254419-qw83atrx	181	19	studied	study	VBN
cord-254419-qw83atrx	181	20	in	in	IN
cord-254419-qw83atrx	181	21	COVID-19	covid-19	CD
cord-254419-qw83atrx	181	22	patients	patient	NNS
cord-254419-qw83atrx	181	23	;	;	:
cord-254419-qw83atrx	181	24	a	a	DT
cord-254419-qw83atrx	181	25	retrospective	retrospective	JJ
cord-254419-qw83atrx	181	26	study	study	NN
cord-254419-qw83atrx	181	27	showed	show	VBD
cord-254419-qw83atrx	181	28	a	a	DT
cord-254419-qw83atrx	181	29	favorable	favorable	JJ
cord-254419-qw83atrx	181	30	recovery	recovery	NN
cord-254419-qw83atrx	181	31	profile	profile	NN
cord-254419-qw83atrx	181	32	and	and	CC
cord-254419-qw83atrx	181	33	lower	lower	VB
cord-254419-qw83atrx	181	34	all	all	DT
cord-254419-qw83atrx	181	35	-	-	HYPH
cord-254419-qw83atrx	181	36	cause	cause	NN
cord-254419-qw83atrx	181	37	mortality	mortality	NN
cord-254419-qw83atrx	181	38	with	with	IN
cord-254419-qw83atrx	181	39	the	the	DT
cord-254419-qw83atrx	181	40	use	use	NN
cord-254419-qw83atrx	181	41	of	of	IN
cord-254419-qw83atrx	181	42	statins	statin	NNS
cord-254419-qw83atrx	181	43	in	in	IN
cord-254419-qw83atrx	181	44	1219	1219	CD
cord-254419-qw83atrx	181	45	hospitalized	hospitalize	VBN
cord-254419-qw83atrx	181	46	patients	patient	NNS
cord-254419-qw83atrx	181	47	with	with	IN
cord-254419-qw83atrx	181	48	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	181	49	[	[	-LRB-
cord-254419-qw83atrx	181	50	63	63	CD
cord-254419-qw83atrx	181	51	]	]	-RRB-
cord-254419-qw83atrx	181	52	.	.	.
cord-254419-qw83atrx	182	1	Convalescent	convalescent	JJ
cord-254419-qw83atrx	182	2	plasma	plasma	NN
cord-254419-qw83atrx	182	3	has	have	VBZ
cord-254419-qw83atrx	182	4	historically	historically	RB
cord-254419-qw83atrx	182	5	been	be	VBN
cord-254419-qw83atrx	182	6	used	use	VBN
cord-254419-qw83atrx	182	7	to	to	TO
cord-254419-qw83atrx	182	8	improve	improve	VB
cord-254419-qw83atrx	182	9	outcomes	outcome	NNS
cord-254419-qw83atrx	182	10	in	in	IN
cord-254419-qw83atrx	182	11	a	a	DT
cord-254419-qw83atrx	182	12	variety	variety	NN
cord-254419-qw83atrx	182	13	of	of	IN
cord-254419-qw83atrx	182	14	viral	viral	JJ
cord-254419-qw83atrx	182	15	epidemics	epidemic	NNS
cord-254419-qw83atrx	182	16	[	[	-LRB-
cord-254419-qw83atrx	182	17	64	64	CD
cord-254419-qw83atrx	182	18	]	]	-RRB-
cord-254419-qw83atrx	182	19	.	.	.
cord-254419-qw83atrx	183	1	In	in	IN
cord-254419-qw83atrx	183	2	theory	theory	NN
cord-254419-qw83atrx	183	3	,	,	,
cord-254419-qw83atrx	183	4	recovered	recover	VBD
cord-254419-qw83atrx	183	5	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	183	6	patients	patient	NNS
cord-254419-qw83atrx	183	7	'	'	POS
cord-254419-qw83atrx	183	8	plasma	plasma	NN
cord-254419-qw83atrx	183	9	containing	contain	VBG
cord-254419-qw83atrx	183	10	anti	anti	NNP
cord-254419-qw83atrx	183	11	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	183	12	neutralizing	neutralize	VBG
cord-254419-qw83atrx	183	13	antibodies	antibody	NNS
cord-254419-qw83atrx	183	14	should	should	MD
cord-254419-qw83atrx	183	15	provide	provide	VB
cord-254419-qw83atrx	183	16	passive	passive	JJ
cord-254419-qw83atrx	183	17	immunity	immunity	NN
cord-254419-qw83atrx	183	18	to	to	IN
cord-254419-qw83atrx	183	19	patients	patient	NNS
cord-254419-qw83atrx	183	20	with	with	IN
cord-254419-qw83atrx	183	21	ongoing	ongoing	JJ
cord-254419-qw83atrx	183	22	disease	disease	NN
cord-254419-qw83atrx	183	23	.	.	.
cord-254419-qw83atrx	184	1	However	however	RB
cord-254419-qw83atrx	184	2	,	,	,
cord-254419-qw83atrx	184	3	a	a	DT
cord-254419-qw83atrx	184	4	recent	recent	JJ
cord-254419-qw83atrx	184	5	systematic	systematic	JJ
cord-254419-qw83atrx	184	6	review	review	NN
cord-254419-qw83atrx	184	7	failed	fail	VBD
cord-254419-qw83atrx	184	8	to	to	TO
cord-254419-qw83atrx	184	9	demonstrate	demonstrate	VB
cord-254419-qw83atrx	184	10	any	any	DT
cord-254419-qw83atrx	184	11	benefit	benefit	NN
cord-254419-qw83atrx	184	12	of	of	IN
cord-254419-qw83atrx	184	13	this	this	DT
cord-254419-qw83atrx	184	14	approach	approach	NN
cord-254419-qw83atrx	184	15	in	in	IN
cord-254419-qw83atrx	184	16	patients	patient	NNS
cord-254419-qw83atrx	184	17	hospitalized	hospitalize	VBN
cord-254419-qw83atrx	184	18	with	with	IN
cord-254419-qw83atrx	184	19	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	184	20	,	,	,
cord-254419-qw83atrx	184	21	in	in	IN
cord-254419-qw83atrx	184	22	addition	addition	NN
cord-254419-qw83atrx	184	23	to	to	IN
cord-254419-qw83atrx	184	24	uncertainty	uncertainty	NN
cord-254419-qw83atrx	184	25	of	of	IN
cord-254419-qw83atrx	184	26	the	the	DT
cord-254419-qw83atrx	184	27	safety	safety	NN
cord-254419-qw83atrx	184	28	profile	profile	NN
cord-254419-qw83atrx	184	29	of	of	IN
cord-254419-qw83atrx	184	30	convalescent	convalescent	JJ
cord-254419-qw83atrx	184	31	plasma	plasma	NN
cord-254419-qw83atrx	184	32	therapy	therapy	NN
cord-254419-qw83atrx	184	33	[	[	-LRB-
cord-254419-qw83atrx	184	34	65	65	CD
cord-254419-qw83atrx	184	35	]	]	-RRB-
cord-254419-qw83atrx	184	36	.	.	.
cord-254419-qw83atrx	185	1	It	-PRON-	PRP
cord-254419-qw83atrx	185	2	has	have	VBZ
cord-254419-qw83atrx	185	3	been	be	VBN
cord-254419-qw83atrx	185	4	a	a	DT
cord-254419-qw83atrx	185	5	steep	steep	JJ
cord-254419-qw83atrx	185	6	learning	learning	NN
cord-254419-qw83atrx	185	7	curve	curve	NN
cord-254419-qw83atrx	185	8	for	for	IN
cord-254419-qw83atrx	185	9	the	the	DT
cord-254419-qw83atrx	185	10	medical	medical	JJ
cord-254419-qw83atrx	185	11	fraternity	fraternity	NN
cord-254419-qw83atrx	185	12	in	in	IN
cord-254419-qw83atrx	185	13	learning	learn	VBG
cord-254419-qw83atrx	185	14	how	how	WRB
cord-254419-qw83atrx	185	15	to	to	TO
cord-254419-qw83atrx	185	16	manage	manage	VB
cord-254419-qw83atrx	185	17	critically	critically	RB
cord-254419-qw83atrx	185	18	ill	ill	VB
cord-254419-qw83atrx	185	19	patients	patient	NNS
cord-254419-qw83atrx	185	20	with	with	IN
cord-254419-qw83atrx	185	21	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	185	22	.	.	.
cord-254419-qw83atrx	186	1	The	the	DT
cord-254419-qw83atrx	186	2	existing	exist	VBG
cord-254419-qw83atrx	186	3	knowledge	knowledge	NN
cord-254419-qw83atrx	186	4	of	of	IN
cord-254419-qw83atrx	186	5	abnormalities	abnormality	NNS
cord-254419-qw83atrx	186	6	in	in	IN
cord-254419-qw83atrx	186	7	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	186	8	and	and	CC
cord-254419-qw83atrx	186	9	coagulation	coagulation	NN
cord-254419-qw83atrx	186	10	pathways	pathway	NNS
cord-254419-qw83atrx	186	11	offers	offer	VBZ
cord-254419-qw83atrx	186	12	opportunities	opportunity	NNS
cord-254419-qw83atrx	186	13	for	for	IN
cord-254419-qw83atrx	186	14	identifying	identify	VBG
cord-254419-qw83atrx	186	15	biomarkers	biomarker	NNS
cord-254419-qw83atrx	186	16	for	for	IN
cord-254419-qw83atrx	186	17	severe	severe	JJ
cord-254419-qw83atrx	186	18	disease	disease	NN
cord-254419-qw83atrx	186	19	,	,	,
cord-254419-qw83atrx	186	20	which	which	WDT
cord-254419-qw83atrx	186	21	combined	combine	VBN
cord-254419-qw83atrx	186	22	with	with	IN
cord-254419-qw83atrx	186	23	clinical	clinical	JJ
cord-254419-qw83atrx	186	24	risk	risk	NN
cord-254419-qw83atrx	186	25	factors	factor	NNS
cord-254419-qw83atrx	186	26	will	will	MD
cord-254419-qw83atrx	186	27	help	help	VB
cord-254419-qw83atrx	186	28	in	in	IN
cord-254419-qw83atrx	186	29	prompt	prompt	JJ
cord-254419-qw83atrx	186	30	identification	identification	NN
cord-254419-qw83atrx	186	31	of	of	IN
cord-254419-qw83atrx	186	32	patients	patient	NNS
cord-254419-qw83atrx	186	33	at	at	IN
cord-254419-qw83atrx	186	34	risk	risk	NN
cord-254419-qw83atrx	186	35	of	of	IN
cord-254419-qw83atrx	186	36	severe	severe	JJ
cord-254419-qw83atrx	186	37	disease	disease	NN
cord-254419-qw83atrx	186	38	who	who	WP
cord-254419-qw83atrx	186	39	require	require	VBP
cord-254419-qw83atrx	186	40	early	early	RB
cord-254419-qw83atrx	186	41	and	and	CC
cord-254419-qw83atrx	186	42	targeted	target	VBN
cord-254419-qw83atrx	186	43	intervention	intervention	NN
cord-254419-qw83atrx	186	44	.	.	.
cord-254419-qw83atrx	187	1	Better	well	JJR
cord-254419-qw83atrx	187	2	understanding	understanding	NN
cord-254419-qw83atrx	187	3	of	of	IN
cord-254419-qw83atrx	187	4	the	the	DT
cord-254419-qw83atrx	187	5	pathophysiology	pathophysiology	NN
cord-254419-qw83atrx	187	6	suggests	suggest	VBZ
cord-254419-qw83atrx	187	7	suppression	suppression	NN
cord-254419-qw83atrx	187	8	of	of	IN
cord-254419-qw83atrx	187	9	the	the	DT
cord-254419-qw83atrx	187	10	adaptive	adaptive	JJ
cord-254419-qw83atrx	187	11	immune	immune	JJ
cord-254419-qw83atrx	187	12	system	system	NN
cord-254419-qw83atrx	187	13	on	on	IN
cord-254419-qw83atrx	187	14	one	one	CD
cord-254419-qw83atrx	187	15	hand	hand	NN
cord-254419-qw83atrx	187	16	and	and	CC
cord-254419-qw83atrx	187	17	a	a	DT
cord-254419-qw83atrx	187	18	hyperactive	hyperactive	JJ
cord-254419-qw83atrx	187	19	innate	innate	JJ
cord-254419-qw83atrx	187	20	immune	immune	JJ
cord-254419-qw83atrx	187	21	system	system	NN
cord-254419-qw83atrx	187	22	on	on	IN
cord-254419-qw83atrx	187	23	the	the	DT
cord-254419-qw83atrx	187	24	other	other	JJ
cord-254419-qw83atrx	187	25	as	as	IN
cord-254419-qw83atrx	187	26	the	the	DT
cord-254419-qw83atrx	187	27	two	two	CD
cord-254419-qw83atrx	187	28	principle	principle	JJ
cord-254419-qw83atrx	187	29	severity	severity	NN
cord-254419-qw83atrx	187	30	-	-	HYPH
cord-254419-qw83atrx	187	31	driving	drive	VBG
cord-254419-qw83atrx	187	32	mechanisms	mechanism	NNS
cord-254419-qw83atrx	187	33	in	in	IN
cord-254419-qw83atrx	187	34	COVID-19	covid-19	JJ
cord-254419-qw83atrx	187	35	infection	infection	NN
cord-254419-qw83atrx	187	36	.	.	.
cord-254419-qw83atrx	188	1	This	this	DT
cord-254419-qw83atrx	188	2	leads	lead	VBZ
cord-254419-qw83atrx	188	3	to	to	IN
cord-254419-qw83atrx	188	4	a	a	DT
cord-254419-qw83atrx	188	5	MAS	MAS	NNP
cord-254419-qw83atrx	188	6	-	-	HYPH
cord-254419-qw83atrx	188	7	like	like	JJ
cord-254419-qw83atrx	188	8	picture	picture	NN
cord-254419-qw83atrx	188	9	associated	associate	VBN
cord-254419-qw83atrx	188	10	with	with	IN
cord-254419-qw83atrx	188	11	a	a	DT
cord-254419-qw83atrx	188	12	hypercoagulable	hypercoagulable	JJ
cord-254419-qw83atrx	188	13	state	state	NN
cord-254419-qw83atrx	188	14	that	that	WDT
cord-254419-qw83atrx	188	15	causes	cause	VBZ
cord-254419-qw83atrx	188	16	both	both	DT
cord-254419-qw83atrx	188	17	micro	micro	JJ
cord-254419-qw83atrx	188	18	and	and	CC
cord-254419-qw83atrx	188	19	macrovascular	macrovascular	JJ
cord-254419-qw83atrx	188	20	thrombosis	thrombosis	NN
cord-254419-qw83atrx	188	21	in	in	IN
cord-254419-qw83atrx	188	22	the	the	DT
cord-254419-qw83atrx	188	23	pulmonary	pulmonary	NN
cord-254419-qw83atrx	188	24	as	as	RB
cord-254419-qw83atrx	188	25	well	well	RB
cord-254419-qw83atrx	188	26	the	the	DT
cord-254419-qw83atrx	188	27	systemic	systemic	JJ
cord-254419-qw83atrx	188	28	circulation	circulation	NN
cord-254419-qw83atrx	188	29	.	.	.
cord-254419-qw83atrx	189	1	This	this	DT
cord-254419-qw83atrx	189	2	understanding	understanding	NN
cord-254419-qw83atrx	189	3	will	will	MD
cord-254419-qw83atrx	189	4	help	help	VB
cord-254419-qw83atrx	189	5	us	-PRON-	PRP
cord-254419-qw83atrx	189	6	develop	develop	VB
cord-254419-qw83atrx	189	7	treatment	treatment	NN
cord-254419-qw83atrx	189	8	protocols	protocol	NNS
cord-254419-qw83atrx	189	9	targeting	target	VBG
cord-254419-qw83atrx	189	10	various	various	JJ
cord-254419-qw83atrx	189	11	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	189	12	pathways	pathway	NNS
cord-254419-qw83atrx	189	13	as	as	RB
cord-254419-qw83atrx	189	14	well	well	RB
cord-254419-qw83atrx	189	15	as	as	IN
cord-254419-qw83atrx	189	16	to	to	TO
cord-254419-qw83atrx	189	17	optimize	optimize	VB
cord-254419-qw83atrx	189	18	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	189	19	therapies	therapy	NNS
cord-254419-qw83atrx	189	20	.	.	.
cord-254419-qw83atrx	190	1	Current	current	JJ
cord-254419-qw83atrx	190	2	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	190	3	practice	practice	NN
cord-254419-qw83atrx	190	4	suggests	suggest	VBZ
cord-254419-qw83atrx	190	5	that	that	IN
cord-254419-qw83atrx	190	6	all	all	DT
cord-254419-qw83atrx	190	7	hospitalized	hospitalize	VBN
cord-254419-qw83atrx	190	8	patients	patient	NNS
cord-254419-qw83atrx	190	9	should	should	MD
cord-254419-qw83atrx	190	10	receive	receive	VB
cord-254419-qw83atrx	190	11	prophylactic	prophylactic	JJ
cord-254419-qw83atrx	190	12	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	190	13	,	,	,
cord-254419-qw83atrx	190	14	those	those	DT
cord-254419-qw83atrx	190	15	with	with	IN
cord-254419-qw83atrx	190	16	severe	severe	JJ
cord-254419-qw83atrx	190	17	disease	disease	NN
cord-254419-qw83atrx	190	18	needing	need	VBG
cord-254419-qw83atrx	190	19	intensive	intensive	JJ
cord-254419-qw83atrx	190	20	care	care	NN
cord-254419-qw83atrx	190	21	with	with	IN
cord-254419-qw83atrx	190	22	respiratory	respiratory	JJ
cord-254419-qw83atrx	190	23	compromise	compromise	NN
cord-254419-qw83atrx	190	24	should	should	MD
cord-254419-qw83atrx	190	25	have	have	VB
cord-254419-qw83atrx	190	26	intermediate	intermediate	JJ
cord-254419-qw83atrx	190	27	dose	dose	NN
cord-254419-qw83atrx	190	28	prophylaxis	prophylaxis	NN
cord-254419-qw83atrx	190	29	and	and	CC
cord-254419-qw83atrx	190	30	therapeutic	therapeutic	JJ
cord-254419-qw83atrx	190	31	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	190	32	reserved	reserve	VBN
cord-254419-qw83atrx	190	33	for	for	IN
cord-254419-qw83atrx	190	34	those	those	DT
cord-254419-qw83atrx	190	35	with	with	IN
cord-254419-qw83atrx	190	36	proven	prove	VBN
cord-254419-qw83atrx	190	37	or	or	CC
cord-254419-qw83atrx	190	38	suspected	suspect	VBN
cord-254419-qw83atrx	190	39	thrombosis	thrombosis	NN
cord-254419-qw83atrx	190	40	.	.	.
cord-254419-qw83atrx	191	1	Results	result	NNS
cord-254419-qw83atrx	191	2	of	of	IN
cord-254419-qw83atrx	191	3	prospective	prospective	JJ
cord-254419-qw83atrx	191	4	trials	trial	NNS
cord-254419-qw83atrx	191	5	will	will	MD
cord-254419-qw83atrx	191	6	only	only	RB
cord-254419-qw83atrx	191	7	answer	answer	VB
cord-254419-qw83atrx	191	8	if	if	IN
cord-254419-qw83atrx	191	9	this	this	DT
cord-254419-qw83atrx	191	10	strategy	strategy	NN
cord-254419-qw83atrx	191	11	is	be	VBZ
cord-254419-qw83atrx	191	12	optimum	optimum	JJ
cord-254419-qw83atrx	191	13	in	in	IN
cord-254419-qw83atrx	191	14	preventing	prevent	VBG
cord-254419-qw83atrx	191	15	thrombotic	thrombotic	JJ
cord-254419-qw83atrx	191	16	complications	complication	NNS
cord-254419-qw83atrx	191	17	and	and	CC
cord-254419-qw83atrx	191	18	improving	improve	VBG
cord-254419-qw83atrx	191	19	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	191	20	and	and	CC
cord-254419-qw83atrx	191	21	overall	overall	JJ
cord-254419-qw83atrx	191	22	outcome	outcome	NN
cord-254419-qw83atrx	191	23	.	.	.
cord-254419-qw83atrx	192	1	A	a	DT
cord-254419-qw83atrx	192	2	multi	multi	JJ
cord-254419-qw83atrx	192	3	-	-	JJ
cord-254419-qw83atrx	192	4	pronged	pronged	JJ
cord-254419-qw83atrx	192	5	approach	approach	NN
cord-254419-qw83atrx	192	6	combining	combine	VBG
cord-254419-qw83atrx	192	7	anti	anti	JJ
cord-254419-qw83atrx	192	8	-	-	JJ
cord-254419-qw83atrx	192	9	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	192	10	drugs	drug	NNS
cord-254419-qw83atrx	192	11	and	and	CC
cord-254419-qw83atrx	192	12	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	192	13	with	with	IN
cord-254419-qw83atrx	192	14	specific	specific	JJ
cord-254419-qw83atrx	192	15	antiviral	antiviral	JJ
cord-254419-qw83atrx	192	16	medications	medication	NNS
cord-254419-qw83atrx	192	17	is	be	VBZ
cord-254419-qw83atrx	192	18	likely	likely	JJ
cord-254419-qw83atrx	192	19	the	the	DT
cord-254419-qw83atrx	192	20	approach	approach	NN
cord-254419-qw83atrx	192	21	that	that	WDT
cord-254419-qw83atrx	192	22	will	will	MD
cord-254419-qw83atrx	192	23	work	work	VB
cord-254419-qw83atrx	192	24	in	in	IN
cord-254419-qw83atrx	192	25	critically	critically	RB
cord-254419-qw83atrx	192	26	ill	ill	JJ
cord-254419-qw83atrx	192	27	patients	patient	NNS
cord-254419-qw83atrx	192	28	(	(	-LRB-
cord-254419-qw83atrx	192	29	Fig	Fig	NNP
cord-254419-qw83atrx	192	30	.	.	.
cord-254419-qw83atrx	192	31	1	1	CD
cord-254419-qw83atrx	192	32	)	)	-RRB-
cord-254419-qw83atrx	192	33	.	.	.
cord-254419-qw83atrx	193	1	Many	many	JJ
cord-254419-qw83atrx	193	2	trials	trial	NNS
cord-254419-qw83atrx	193	3	are	be	VBP
cord-254419-qw83atrx	193	4	currently	currently	RB
cord-254419-qw83atrx	193	5	trying	try	VBG
cord-254419-qw83atrx	193	6	to	to	TO
cord-254419-qw83atrx	193	7	address	address	VB
cord-254419-qw83atrx	193	8	efficacy	efficacy	NN
cord-254419-qw83atrx	193	9	of	of	IN
cord-254419-qw83atrx	193	10	different	different	JJ
cord-254419-qw83atrx	193	11	antiviral	antiviral	JJ
cord-254419-qw83atrx	193	12	,	,	,
cord-254419-qw83atrx	193	13	anti	anti	JJ
cord-254419-qw83atrx	193	14	-	-	JJ
cord-254419-qw83atrx	193	15	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	193	16	,	,	,
cord-254419-qw83atrx	193	17	and	and	CC
cord-254419-qw83atrx	193	18	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	193	19	agents	agent	NNS
cord-254419-qw83atrx	193	20	in	in	IN
cord-254419-qw83atrx	193	21	isolation	isolation	NN
cord-254419-qw83atrx	193	22	.	.	.
cord-254419-qw83atrx	194	1	Unfortunately	unfortunately	RB
cord-254419-qw83atrx	194	2	,	,	,
cord-254419-qw83atrx	194	3	these	these	DT
cord-254419-qw83atrx	194	4	trials	trial	NNS
cord-254419-qw83atrx	194	5	may	may	MD
cord-254419-qw83atrx	194	6	take	take	VB
cord-254419-qw83atrx	194	7	a	a	DT
cord-254419-qw83atrx	194	8	significant	significant	JJ
cord-254419-qw83atrx	194	9	amount	amount	NN
cord-254419-qw83atrx	194	10	of	of	IN
cord-254419-qw83atrx	194	11	time	time	NN
cord-254419-qw83atrx	194	12	for	for	IN
cord-254419-qw83atrx	194	13	completion	completion	NN
cord-254419-qw83atrx	194	14	and	and	CC
cord-254419-qw83atrx	194	15	analysis	analysis	NN
cord-254419-qw83atrx	194	16	before	before	IN
cord-254419-qw83atrx	194	17	the	the	DT
cord-254419-qw83atrx	194	18	evidence	evidence	NN
cord-254419-qw83atrx	194	19	-	-	HYPH
cord-254419-qw83atrx	194	20	based	base	VBN
cord-254419-qw83atrx	194	21	recommendations	recommendation	NNS
cord-254419-qw83atrx	194	22	can	can	MD
cord-254419-qw83atrx	194	23	be	be	VB
cord-254419-qw83atrx	194	24	produced	produce	VBN
cord-254419-qw83atrx	194	25	.	.	.
cord-254419-qw83atrx	195	1	Because	because	IN
cord-254419-qw83atrx	195	2	of	of	IN
cord-254419-qw83atrx	195	3	the	the	DT
cord-254419-qw83atrx	195	4	enormous	enormous	JJ
cord-254419-qw83atrx	195	5	number	number	NN
cord-254419-qw83atrx	195	6	of	of	IN
cord-254419-qw83atrx	195	7	new	new	JJ
cord-254419-qw83atrx	195	8	patients	patient	NNS
cord-254419-qw83atrx	195	9	over	over	IN
cord-254419-qw83atrx	195	10	a	a	DT
cord-254419-qw83atrx	195	11	short	short	JJ
cord-254419-qw83atrx	195	12	period	period	NN
cord-254419-qw83atrx	195	13	,	,	,
cord-254419-qw83atrx	195	14	we	-PRON-	PRP
cord-254419-qw83atrx	195	15	have	have	VBP
cord-254419-qw83atrx	195	16	a	a	DT
cord-254419-qw83atrx	195	17	unique	unique	JJ
cord-254419-qw83atrx	195	18	opportunity	opportunity	NN
cord-254419-qw83atrx	195	19	to	to	TO
cord-254419-qw83atrx	195	20	develop	develop	VB
cord-254419-qw83atrx	195	21	an	an	DT
cord-254419-qw83atrx	195	22	international	international	JJ
cord-254419-qw83atrx	195	23	collaborative	collaborative	JJ
cord-254419-qw83atrx	195	24	network	network	NN
cord-254419-qw83atrx	195	25	and	and	CC
cord-254419-qw83atrx	195	26	conduct	conduct	VB
cord-254419-qw83atrx	195	27	large	large	JJ
cord-254419-qw83atrx	195	28	trials	trial	NNS
cord-254419-qw83atrx	195	29	with	with	IN
cord-254419-qw83atrx	195	30	many	many	JJ
cord-254419-qw83atrx	195	31	combination	combination	NN
cord-254419-qw83atrx	195	32	arms	arm	NNS
cord-254419-qw83atrx	195	33	to	to	TO
cord-254419-qw83atrx	195	34	answer	answer	VB
cord-254419-qw83atrx	195	35	the	the	DT
cord-254419-qw83atrx	195	36	all	all	RB
cord-254419-qw83atrx	195	37	-	-	HYPH
cord-254419-qw83atrx	195	38	important	important	JJ
cord-254419-qw83atrx	195	39	question	question	NN
cord-254419-qw83atrx	195	40	of	of	IN
cord-254419-qw83atrx	195	41	which	which	WDT
cord-254419-qw83atrx	195	42	combination	combination	NN
cord-254419-qw83atrx	195	43	of	of	IN
cord-254419-qw83atrx	195	44	antiviral	antiviral	JJ
cord-254419-qw83atrx	195	45	,	,	,
cord-254419-qw83atrx	195	46	anti	anti	JJ
cord-254419-qw83atrx	195	47	-	-	JJ
cord-254419-qw83atrx	195	48	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	195	49	drugs	drug	NNS
cord-254419-qw83atrx	195	50	with	with	IN
cord-254419-qw83atrx	195	51	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	195	52	therapies	therapy	NNS
cord-254419-qw83atrx	195	53	are	be	VBP
cord-254419-qw83atrx	195	54	going	go	VBG
cord-254419-qw83atrx	195	55	to	to	TO
cord-254419-qw83atrx	195	56	be	be	VB
cord-254419-qw83atrx	195	57	the	the	DT
cord-254419-qw83atrx	195	58	most	most	RBS
cord-254419-qw83atrx	195	59	effective	effective	JJ
cord-254419-qw83atrx	195	60	in	in	IN
cord-254419-qw83atrx	195	61	treating	treat	VBG
cord-254419-qw83atrx	195	62	patients	patient	NNS
cord-254419-qw83atrx	195	63	with	with	IN
cord-254419-qw83atrx	195	64	severe	severe	JJ
cord-254419-qw83atrx	195	65	disease	disease	NN
cord-254419-qw83atrx	195	66	.	.	.
cord-254419-qw83atrx	196	1	Early	early	JJ
cord-254419-qw83atrx	196	2	intervention	intervention	NN
cord-254419-qw83atrx	196	3	strategy	strategy	NN
cord-254419-qw83atrx	196	4	is	be	VBZ
cord-254419-qw83atrx	196	5	likely	likely	JJ
cord-254419-qw83atrx	196	6	to	to	TO
cord-254419-qw83atrx	196	7	be	be	VB
cord-254419-qw83atrx	196	8	helpful	helpful	JJ
cord-254419-qw83atrx	196	9	in	in	IN
cord-254419-qw83atrx	196	10	preventing	prevent	VBG
cord-254419-qw83atrx	196	11	disease	disease	NN
cord-254419-qw83atrx	196	12	progression	progression	NN
cord-254419-qw83atrx	196	13	and	and	CC
cord-254419-qw83atrx	196	14	thereby	thereby	RB
cord-254419-qw83atrx	196	15	reducing	reduce	VBG
cord-254419-qw83atrx	196	16	the	the	DT
cord-254419-qw83atrx	196	17	morbidity	morbidity	NN
cord-254419-qw83atrx	196	18	and	and	CC
cord-254419-qw83atrx	196	19	mortality	mortality	NN
cord-254419-qw83atrx	196	20	from	from	IN
cord-254419-qw83atrx	196	21	this	this	DT
cord-254419-qw83atrx	196	22	pandemic	pandemic	NN
cord-254419-qw83atrx	196	23	.	.	.
cord-254419-qw83atrx	197	1	Funding	funding	NN
cord-254419-qw83atrx	197	2	.	.	.
cord-254419-qw83atrx	198	1	No	no	DT
cord-254419-qw83atrx	198	2	funding	funding	NN
cord-254419-qw83atrx	198	3	or	or	CC
cord-254419-qw83atrx	198	4	sponsorship	sponsorship	NN
cord-254419-qw83atrx	198	5	was	be	VBD
cord-254419-qw83atrx	198	6	received	receive	VBN
cord-254419-qw83atrx	198	7	for	for	IN
cord-254419-qw83atrx	198	8	this	this	DT
cord-254419-qw83atrx	198	9	study	study	NN
cord-254419-qw83atrx	198	10	or	or	CC
cord-254419-qw83atrx	198	11	publication	publication	NN
cord-254419-qw83atrx	198	12	of	of	IN
cord-254419-qw83atrx	198	13	this	this	DT
cord-254419-qw83atrx	198	14	article	article	NN
cord-254419-qw83atrx	198	15	.	.	.
cord-254419-qw83atrx	199	1	Authorship	authorship	NN
cord-254419-qw83atrx	199	2	.	.	.
cord-254419-qw83atrx	200	1	All	all	DT
cord-254419-qw83atrx	200	2	named	name	VBN
cord-254419-qw83atrx	200	3	authors	author	NNS
cord-254419-qw83atrx	200	4	meet	meet	VBP
cord-254419-qw83atrx	200	5	the	the	DT
cord-254419-qw83atrx	200	6	International	International	NNP
cord-254419-qw83atrx	200	7	Committee	Committee	NNP
cord-254419-qw83atrx	200	8	of	of	IN
cord-254419-qw83atrx	200	9	Medical	Medical	NNP
cord-254419-qw83atrx	200	10	Journal	Journal	NNP
cord-254419-qw83atrx	200	11	Editors	Editors	NNPS
cord-254419-qw83atrx	200	12	(	(	-LRB-
cord-254419-qw83atrx	200	13	ICMJE	ICMJE	NNP
cord-254419-qw83atrx	200	14	)	)	-RRB-
cord-254419-qw83atrx	200	15	criteria	criterion	NNS
cord-254419-qw83atrx	200	16	for	for	IN
cord-254419-qw83atrx	200	17	authorship	authorship	NN
cord-254419-qw83atrx	200	18	for	for	IN
cord-254419-qw83atrx	200	19	this	this	DT
cord-254419-qw83atrx	200	20	article	article	NN
cord-254419-qw83atrx	200	21	,	,	,
cord-254419-qw83atrx	200	22	take	take	VB
cord-254419-qw83atrx	200	23	responsibility	responsibility	NN
cord-254419-qw83atrx	200	24	for	for	IN
cord-254419-qw83atrx	200	25	the	the	DT
cord-254419-qw83atrx	200	26	integrity	integrity	NN
cord-254419-qw83atrx	200	27	of	of	IN
cord-254419-qw83atrx	200	28	the	the	DT
cord-254419-qw83atrx	200	29	work	work	NN
cord-254419-qw83atrx	200	30	as	as	IN
cord-254419-qw83atrx	200	31	a	a	DT
cord-254419-qw83atrx	200	32	whole	whole	NN
cord-254419-qw83atrx	200	33	,	,	,
cord-254419-qw83atrx	200	34	and	and	CC
cord-254419-qw83atrx	200	35	have	have	VBP
cord-254419-qw83atrx	200	36	given	give	VBN
cord-254419-qw83atrx	200	37	their	-PRON-	PRP$
cord-254419-qw83atrx	200	38	approval	approval	NN
cord-254419-qw83atrx	200	39	for	for	IN
cord-254419-qw83atrx	200	40	this	this	DT
cord-254419-qw83atrx	200	41	version	version	NN
cord-254419-qw83atrx	200	42	to	to	TO
cord-254419-qw83atrx	200	43	be	be	VB
cord-254419-qw83atrx	200	44	published	publish	VBN
cord-254419-qw83atrx	200	45	.	.	.
cord-254419-qw83atrx	201	1	Disclosures	disclosure	NNS
cord-254419-qw83atrx	201	2	.	.	.
cord-254419-qw83atrx	202	1	Rajat	Rajat	NNP
cord-254419-qw83atrx	202	2	Bhattacharyya	Bhattacharyya	NNP
cord-254419-qw83atrx	202	3	,	,	,
cord-254419-qw83atrx	202	4	Prasad	Prasad	NNP
cord-254419-qw83atrx	202	5	Iyer	Iyer	NNP
cord-254419-qw83atrx	202	6	,	,	,
cord-254419-qw83atrx	202	7	Ghee	Ghee	NNP
cord-254419-qw83atrx	202	8	Chee	Chee	NNP
cord-254419-qw83atrx	202	9	Phua	Phua	NNP
cord-254419-qw83atrx	202	10	,	,	,
cord-254419-qw83atrx	202	11	and	and	CC
cord-254419-qw83atrx	202	12	Lee	Lee	NNP
cord-254419-qw83atrx	202	13	Jan	Jan	NNP
cord-254419-qw83atrx	202	14	Hau	Hau	NNP
cord-254419-qw83atrx	202	15	have	have	VB
cord-254419-qw83atrx	202	16	nothing	nothing	NN
cord-254419-qw83atrx	202	17	to	to	TO
cord-254419-qw83atrx	202	18	disclose	disclose	VB
cord-254419-qw83atrx	202	19	.	.	.
cord-254419-qw83atrx	203	1	Compliance	compliance	NN
cord-254419-qw83atrx	203	2	with	with	IN
cord-254419-qw83atrx	203	3	Ethics	Ethics	NNP
cord-254419-qw83atrx	203	4	Guidelines	Guidelines	NNPS
cord-254419-qw83atrx	203	5	.	.	.
cord-254419-qw83atrx	204	1	This	this	DT
cord-254419-qw83atrx	204	2	article	article	NN
cord-254419-qw83atrx	204	3	is	be	VBZ
cord-254419-qw83atrx	204	4	based	base	VBN
cord-254419-qw83atrx	204	5	on	on	IN
cord-254419-qw83atrx	204	6	previously	previously	RB
cord-254419-qw83atrx	204	7	conducted	conduct	VBN
cord-254419-qw83atrx	204	8	studies	study	NNS
cord-254419-qw83atrx	204	9	and	and	CC
cord-254419-qw83atrx	204	10	does	do	VBZ
cord-254419-qw83atrx	204	11	not	not	RB
cord-254419-qw83atrx	204	12	contain	contain	VB
cord-254419-qw83atrx	204	13	any	any	DT
cord-254419-qw83atrx	204	14	studies	study	NNS
cord-254419-qw83atrx	204	15	with	with	IN
cord-254419-qw83atrx	204	16	human	human	JJ
cord-254419-qw83atrx	204	17	participants	participant	NNS
cord-254419-qw83atrx	204	18	or	or	CC
cord-254419-qw83atrx	204	19	animals	animal	NNS
cord-254419-qw83atrx	204	20	performed	perform	VBN
cord-254419-qw83atrx	204	21	by	by	IN
cord-254419-qw83atrx	204	22	any	any	DT
cord-254419-qw83atrx	204	23	of	of	IN
cord-254419-qw83atrx	204	24	the	the	DT
cord-254419-qw83atrx	204	25	authors	author	NNS
cord-254419-qw83atrx	204	26	.	.	.
cord-254419-qw83atrx	205	1	Data	datum	NNS
cord-254419-qw83atrx	205	2	Availability	availability	NN
cord-254419-qw83atrx	205	3	.	.	.
cord-254419-qw83atrx	206	1	Data	datum	NNS
cord-254419-qw83atrx	206	2	sharing	sharing	NN
cord-254419-qw83atrx	206	3	is	be	VBZ
cord-254419-qw83atrx	206	4	not	not	RB
cord-254419-qw83atrx	206	5	applicable	applicable	JJ
cord-254419-qw83atrx	206	6	to	to	IN
cord-254419-qw83atrx	206	7	this	this	DT
cord-254419-qw83atrx	206	8	article	article	NN
cord-254419-qw83atrx	206	9	,	,	,
cord-254419-qw83atrx	206	10	as	as	IN
cord-254419-qw83atrx	206	11	no	no	DT
cord-254419-qw83atrx	206	12	datasets	dataset	NNS
cord-254419-qw83atrx	206	13	were	be	VBD
cord-254419-qw83atrx	206	14	generated	generate	VBN
cord-254419-qw83atrx	206	15	or	or	CC
cord-254419-qw83atrx	206	16	analyzed	analyze	VBN
cord-254419-qw83atrx	206	17	during	during	IN
cord-254419-qw83atrx	206	18	the	the	DT
cord-254419-qw83atrx	206	19	current	current	JJ
cord-254419-qw83atrx	206	20	study	study	NN
cord-254419-qw83atrx	206	21	Open	Open	NNP
cord-254419-qw83atrx	206	22	Access	Access	NNP
cord-254419-qw83atrx	206	23	.	.	.
cord-254419-qw83atrx	207	1	This	this	DT
cord-254419-qw83atrx	207	2	article	article	NN
cord-254419-qw83atrx	207	3	is	be	VBZ
cord-254419-qw83atrx	207	4	licensed	license	VBN
cord-254419-qw83atrx	207	5	under	under	IN
cord-254419-qw83atrx	207	6	a	a	DT
cord-254419-qw83atrx	207	7	Creative	Creative	NNP
cord-254419-qw83atrx	207	8	Commons	Commons	NNP
cord-254419-qw83atrx	207	9	Attribution	Attribution	NNP
cord-254419-qw83atrx	207	10	-	-	HYPH
cord-254419-qw83atrx	207	11	NonCommercial	NonCommercial	NNP
cord-254419-qw83atrx	207	12	4.0	4.0	CD
cord-254419-qw83atrx	207	13	International	International	NNP
cord-254419-qw83atrx	207	14	License	License	NNP
cord-254419-qw83atrx	207	15	,	,	,
cord-254419-qw83atrx	207	16	which	which	WDT
cord-254419-qw83atrx	207	17	permits	permit	VBZ
cord-254419-qw83atrx	207	18	any	any	DT
cord-254419-qw83atrx	207	19	non	non	JJ
cord-254419-qw83atrx	207	20	-	-	JJ
cord-254419-qw83atrx	207	21	commercial	commercial	JJ
cord-254419-qw83atrx	207	22	use	use	NN
cord-254419-qw83atrx	207	23	,	,	,
cord-254419-qw83atrx	207	24	sharing	sharing	NN
cord-254419-qw83atrx	207	25	,	,	,
cord-254419-qw83atrx	207	26	adaptation	adaptation	NN
cord-254419-qw83atrx	207	27	,	,	,
cord-254419-qw83atrx	207	28	distribution	distribution	NN
cord-254419-qw83atrx	207	29	and	and	CC
cord-254419-qw83atrx	207	30	reproduction	reproduction	NN
cord-254419-qw83atrx	207	31	in	in	IN
cord-254419-qw83atrx	207	32	any	any	DT
cord-254419-qw83atrx	207	33	medium	medium	NN
cord-254419-qw83atrx	207	34	or	or	CC
cord-254419-qw83atrx	207	35	format	format	NN
cord-254419-qw83atrx	207	36	,	,	,
cord-254419-qw83atrx	207	37	as	as	RB
cord-254419-qw83atrx	207	38	long	long	RB
cord-254419-qw83atrx	207	39	as	as	IN
cord-254419-qw83atrx	207	40	you	-PRON-	PRP
cord-254419-qw83atrx	207	41	give	give	VBP
cord-254419-qw83atrx	207	42	appropriate	appropriate	JJ
cord-254419-qw83atrx	207	43	credit	credit	NN
cord-254419-qw83atrx	207	44	to	to	IN
cord-254419-qw83atrx	207	45	the	the	DT
cord-254419-qw83atrx	207	46	original	original	JJ
cord-254419-qw83atrx	207	47	author(s	author(s	NNP
cord-254419-qw83atrx	207	48	)	)	-RRB-
cord-254419-qw83atrx	207	49	and	and	CC
cord-254419-qw83atrx	207	50	the	the	DT
cord-254419-qw83atrx	207	51	source	source	NN
cord-254419-qw83atrx	207	52	,	,	,
cord-254419-qw83atrx	207	53	provide	provide	VB
cord-254419-qw83atrx	207	54	a	a	DT
cord-254419-qw83atrx	207	55	link	link	NN
cord-254419-qw83atrx	207	56	to	to	IN
cord-254419-qw83atrx	207	57	the	the	DT
cord-254419-qw83atrx	207	58	Creative	Creative	NNP
cord-254419-qw83atrx	207	59	Commons	Commons	NNP
cord-254419-qw83atrx	207	60	licence	licence	NN
cord-254419-qw83atrx	207	61	,	,	,
cord-254419-qw83atrx	207	62	and	and	CC
cord-254419-qw83atrx	207	63	indicate	indicate	VBP
cord-254419-qw83atrx	207	64	if	if	IN
cord-254419-qw83atrx	207	65	changes	change	NNS
cord-254419-qw83atrx	207	66	were	be	VBD
cord-254419-qw83atrx	207	67	made	make	VBN
cord-254419-qw83atrx	207	68	.	.	.
cord-254419-qw83atrx	208	1	The	the	DT
cord-254419-qw83atrx	208	2	images	image	NNS
cord-254419-qw83atrx	208	3	or	or	CC
cord-254419-qw83atrx	208	4	other	other	JJ
cord-254419-qw83atrx	208	5	third	third	JJ
cord-254419-qw83atrx	208	6	party	party	NN
cord-254419-qw83atrx	208	7	material	material	NN
cord-254419-qw83atrx	208	8	in	in	IN
cord-254419-qw83atrx	208	9	this	this	DT
cord-254419-qw83atrx	208	10	article	article	NN
cord-254419-qw83atrx	208	11	are	be	VBP
cord-254419-qw83atrx	208	12	included	include	VBN
cord-254419-qw83atrx	208	13	in	in	IN
cord-254419-qw83atrx	208	14	the	the	DT
cord-254419-qw83atrx	208	15	article	article	NN
cord-254419-qw83atrx	208	16	's	's	POS
cord-254419-qw83atrx	208	17	Creative	Creative	NNP
cord-254419-qw83atrx	208	18	Commons	Commons	NNP
cord-254419-qw83atrx	208	19	licence	licence	NN
cord-254419-qw83atrx	208	20	,	,	,
cord-254419-qw83atrx	208	21	unless	unless	IN
cord-254419-qw83atrx	208	22	indicated	indicate	VBN
cord-254419-qw83atrx	208	23	otherwise	otherwise	RB
cord-254419-qw83atrx	208	24	in	in	IN
cord-254419-qw83atrx	208	25	a	a	DT
cord-254419-qw83atrx	208	26	credit	credit	NN
cord-254419-qw83atrx	208	27	line	line	NN
cord-254419-qw83atrx	208	28	to	to	IN
cord-254419-qw83atrx	208	29	the	the	DT
cord-254419-qw83atrx	208	30	material	material	NN
cord-254419-qw83atrx	208	31	.	.	.
cord-254419-qw83atrx	209	1	If	if	IN
cord-254419-qw83atrx	209	2	material	material	NN
cord-254419-qw83atrx	209	3	is	be	VBZ
cord-254419-qw83atrx	209	4	not	not	RB
cord-254419-qw83atrx	209	5	included	include	VBN
cord-254419-qw83atrx	209	6	in	in	IN
cord-254419-qw83atrx	209	7	the	the	DT
cord-254419-qw83atrx	209	8	article	article	NN
cord-254419-qw83atrx	209	9	's	's	POS
cord-254419-qw83atrx	209	10	Creative	Creative	NNP
cord-254419-qw83atrx	209	11	Commons	Commons	NNP
cord-254419-qw83atrx	209	12	licence	licence	NN
cord-254419-qw83atrx	209	13	and	and	CC
cord-254419-qw83atrx	209	14	your	-PRON-	PRP$
cord-254419-qw83atrx	209	15	intended	intend	VBN
cord-254419-qw83atrx	209	16	use	use	NN
cord-254419-qw83atrx	209	17	is	be	VBZ
cord-254419-qw83atrx	209	18	not	not	RB
cord-254419-qw83atrx	209	19	permitted	permit	VBN
cord-254419-qw83atrx	209	20	by	by	IN
cord-254419-qw83atrx	209	21	statutory	statutory	JJ
cord-254419-qw83atrx	209	22	regulation	regulation	NN
cord-254419-qw83atrx	209	23	or	or	CC
cord-254419-qw83atrx	209	24	exceeds	exceed	VBZ
cord-254419-qw83atrx	209	25	the	the	DT
cord-254419-qw83atrx	209	26	permitted	permit	VBN
cord-254419-qw83atrx	209	27	use	use	NN
cord-254419-qw83atrx	209	28	,	,	,
cord-254419-qw83atrx	209	29	you	-PRON-	PRP
cord-254419-qw83atrx	209	30	will	will	MD
cord-254419-qw83atrx	209	31	need	need	VB
cord-254419-qw83atrx	209	32	to	to	TO
cord-254419-qw83atrx	209	33	obtain	obtain	VB
cord-254419-qw83atrx	209	34	permission	permission	NN
cord-254419-qw83atrx	209	35	directly	directly	RB
cord-254419-qw83atrx	209	36	from	from	IN
cord-254419-qw83atrx	209	37	the	the	DT
cord-254419-qw83atrx	209	38	copyright	copyright	NN
cord-254419-qw83atrx	209	39	holder	holder	NN
cord-254419-qw83atrx	209	40	.	.	.
cord-254419-qw83atrx	210	1	To	to	TO
cord-254419-qw83atrx	210	2	view	view	VB
cord-254419-qw83atrx	210	3	a	a	DT
cord-254419-qw83atrx	210	4	copy	copy	NN
cord-254419-qw83atrx	210	5	of	of	IN
cord-254419-qw83atrx	210	6	this	this	DT
cord-254419-qw83atrx	210	7	licence	licence	NN
cord-254419-qw83atrx	210	8	,	,	,
cord-254419-qw83atrx	210	9	visit	visit	VB
cord-254419-qw83atrx	210	10	http://creativecommons.org/licenses/bync/4.0/.	http://creativecommons.org/licenses/bync/4.0/.	NNP
cord-254419-qw83atrx	211	1	COVID-19	covid-19	JJ
cord-254419-qw83atrx	211	2	outbreak	outbreak	NN
cord-254419-qw83atrx	211	3	in	in	IN
cord-254419-qw83atrx	211	4	China	China	NNP
cord-254419-qw83atrx	211	5	:	:	:
cord-254419-qw83atrx	211	6	summary	summary	NN
cord-254419-qw83atrx	211	7	of	of	IN
cord-254419-qw83atrx	211	8	a	a	DT
cord-254419-qw83atrx	211	9	report	report	NN
cord-254419-qw83atrx	211	10	of	of	IN
cord-254419-qw83atrx	211	11	72,314	72,314	CD
cord-254419-qw83atrx	211	12	cases	case	NNS
cord-254419-qw83atrx	211	13	from	from	IN
cord-254419-qw83atrx	211	14	the	the	DT
cord-254419-qw83atrx	211	15	Chinese	Chinese	NNP
cord-254419-qw83atrx	211	16	Center	Center	NNP
cord-254419-qw83atrx	211	17	for	for	IN
cord-254419-qw83atrx	211	18	Disease	Disease	NNP
cord-254419-qw83atrx	211	19	Control	Control	NNP
cord-254419-qw83atrx	211	20	and	and	CC
cord-254419-qw83atrx	211	21	Prevention	Prevention	NNP
cord-254419-qw83atrx	212	1	Clinical	clinical	JJ
cord-254419-qw83atrx	212	2	course	course	NN
cord-254419-qw83atrx	212	3	and	and	CC
cord-254419-qw83atrx	212	4	outcomes	outcome	NNS
cord-254419-qw83atrx	212	5	of	of	IN
cord-254419-qw83atrx	212	6	critically	critically	RB
cord-254419-qw83atrx	212	7	ill	ill	JJ
cord-254419-qw83atrx	212	8	patients	patient	NNS
cord-254419-qw83atrx	212	9	with	with	IN
cord-254419-qw83atrx	212	10	SARS	SARS	NNP
cord-254419-qw83atrx	212	11	-	-	HYPH
cord-254419-qw83atrx	212	12	CoV-2	CoV-2	NNP
cord-254419-qw83atrx	212	13	pneumonia	pneumonia	NN
cord-254419-qw83atrx	212	14	in	in	IN
cord-254419-qw83atrx	212	15	Wuhan	Wuhan	NNP
cord-254419-qw83atrx	212	16	,	,	,
cord-254419-qw83atrx	212	17	China	China	NNP
cord-254419-qw83atrx	212	18	:	:	:
cord-254419-qw83atrx	212	19	a	a	DT
cord-254419-qw83atrx	212	20	single	single	RB
cord-254419-qw83atrx	212	21	-	-	HYPH
cord-254419-qw83atrx	212	22	centered	centered	JJ
cord-254419-qw83atrx	212	23	,	,	,
cord-254419-qw83atrx	212	24	retrospective	retrospective	JJ
cord-254419-qw83atrx	212	25	,	,	,
cord-254419-qw83atrx	212	26	observational	observational	JJ
cord-254419-qw83atrx	212	27	study	study	NN
cord-254419-qw83atrx	212	28	Comparison	comparison	NN
cord-254419-qw83atrx	212	29	of	of	IN
cord-254419-qw83atrx	212	30	clinical	clinical	JJ
cord-254419-qw83atrx	212	31	and	and	CC
cord-254419-qw83atrx	212	32	pathological	pathological	JJ
cord-254419-qw83atrx	212	33	features	feature	NNS
cord-254419-qw83atrx	212	34	between	between	IN
cord-254419-qw83atrx	212	35	severe	severe	JJ
cord-254419-qw83atrx	212	36	acute	acute	JJ
cord-254419-qw83atrx	212	37	respiratory	respiratory	JJ
cord-254419-qw83atrx	212	38	syndrome	syndrome	NN
cord-254419-qw83atrx	212	39	and	and	CC
cord-254419-qw83atrx	212	40	coronavirus	coronavirus	NN
cord-254419-qw83atrx	212	41	disease	disease	NN
cord-254419-qw83atrx	213	1	2019	2019	CD
cord-254419-qw83atrx	213	2	Microvascular	Microvascular	NNP
cord-254419-qw83atrx	213	3	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	213	4	lung	lung	NN
cord-254419-qw83atrx	213	5	vessels	vessel	NNS
cord-254419-qw83atrx	213	6	obstructive	obstructive	JJ
cord-254419-qw83atrx	213	7	thromboinflammatory	thromboinflammatory	NNP
cord-254419-qw83atrx	213	8	syndrome	syndrome	NN
cord-254419-qw83atrx	214	1	(	(	-LRB-
cord-254419-qw83atrx	214	2	MicroCLOTS	MicroCLOTS	NNP
cord-254419-qw83atrx	214	3	)	)	-RRB-
cord-254419-qw83atrx	214	4	:	:	:
cord-254419-qw83atrx	214	5	an	an	DT
cord-254419-qw83atrx	214	6	atypical	atypical	JJ
cord-254419-qw83atrx	214	7	acute	acute	JJ
cord-254419-qw83atrx	214	8	respiratory	respiratory	JJ
cord-254419-qw83atrx	214	9	distress	distress	NN
cord-254419-qw83atrx	214	10	syndrome	syndrome	NN
cord-254419-qw83atrx	214	11	working	work	VBG
cord-254419-qw83atrx	214	12	hypothesis	hypothesis	NN
cord-254419-qw83atrx	215	1	A	a	DT
cord-254419-qw83atrx	215	2	novel	novel	JJ
cord-254419-qw83atrx	215	3	coronavirus	coronavirus	NN
cord-254419-qw83atrx	215	4	from	from	IN
cord-254419-qw83atrx	215	5	patients	patient	NNS
cord-254419-qw83atrx	215	6	with	with	IN
cord-254419-qw83atrx	215	7	pneumonia	pneumonia	NN
cord-254419-qw83atrx	215	8	in	in	IN
cord-254419-qw83atrx	215	9	China	China	NNP
cord-254419-qw83atrx	216	1	The	the	DT
cord-254419-qw83atrx	216	2	science	science	NN
cord-254419-qw83atrx	216	3	underlying	underlie	VBG
cord-254419-qw83atrx	216	4	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	216	5	:	:	:
cord-254419-qw83atrx	216	6	implications	implication	NNS
cord-254419-qw83atrx	216	7	for	for	IN
cord-254419-qw83atrx	216	8	the	the	DT
cord-254419-qw83atrx	216	9	cardiovascular	cardiovascular	JJ
cord-254419-qw83atrx	216	10	system	system	NN
cord-254419-qw83atrx	216	11	SARS	SARS	NNP
cord-254419-qw83atrx	216	12	-	-	HYPH
cord-254419-qw83atrx	216	13	CoV-2	CoV-2	NNP
cord-254419-qw83atrx	216	14	cell	cell	NN
cord-254419-qw83atrx	216	15	entry	entry	NN
cord-254419-qw83atrx	216	16	depends	depend	VBZ
cord-254419-qw83atrx	216	17	on	on	IN
cord-254419-qw83atrx	216	18	ACE2	ACE2	NNP
cord-254419-qw83atrx	216	19	and	and	CC
cord-254419-qw83atrx	216	20	TMPRSS2	TMPRSS2	NNP
cord-254419-qw83atrx	216	21	and	and	CC
cord-254419-qw83atrx	216	22	is	be	VBZ
cord-254419-qw83atrx	216	23	blocked	block	VBN
cord-254419-qw83atrx	216	24	by	by	IN
cord-254419-qw83atrx	216	25	a	a	DT
cord-254419-qw83atrx	216	26	clinically	clinically	RB
cord-254419-qw83atrx	216	27	proven	prove	VBN
cord-254419-qw83atrx	216	28	protease	protease	NN
cord-254419-qw83atrx	216	29	inhibitor	inhibitor	NN
cord-254419-qw83atrx	216	30	COVID-19	covid-19	CD
cord-254419-qw83atrx	216	31	infection	infection	NN
cord-254419-qw83atrx	216	32	:	:	:
cord-254419-qw83atrx	216	33	origin	origin	NN
cord-254419-qw83atrx	216	34	,	,	,
cord-254419-qw83atrx	216	35	transmission	transmission	NN
cord-254419-qw83atrx	216	36	,	,	,
cord-254419-qw83atrx	216	37	and	and	CC
cord-254419-qw83atrx	216	38	characteristics	characteristic	NNS
cord-254419-qw83atrx	216	39	of	of	IN
cord-254419-qw83atrx	216	40	human	human	JJ
cord-254419-qw83atrx	216	41	coronaviruses	coronaviruse	NNS
cord-254419-qw83atrx	216	42	Effect	Effect	NNP
cord-254419-qw83atrx	216	43	of	of	IN
cord-254419-qw83atrx	216	44	angiotensin	angiotensin	NN
cord-254419-qw83atrx	216	45	-	-	HYPH
cord-254419-qw83atrx	216	46	converting	convert	VBG
cord-254419-qw83atrx	216	47	enzyme	enzyme	NN
cord-254419-qw83atrx	216	48	inhibition	inhibition	NN
cord-254419-qw83atrx	216	49	and	and	CC
cord-254419-qw83atrx	216	50	angiotensin	angiotensin	NN
cord-254419-qw83atrx	216	51	II	ii	CD
cord-254419-qw83atrx	216	52	receptor	receptor	NN
cord-254419-qw83atrx	216	53	blockers	blocker	NNS
cord-254419-qw83atrx	216	54	on	on	IN
cord-254419-qw83atrx	216	55	cardiac	cardiac	JJ
cord-254419-qw83atrx	216	56	angiotensinconverting	angiotensinconverting	NN
cord-254419-qw83atrx	216	57	enzyme	enzyme	NN
cord-254419-qw83atrx	216	58	2	2	CD
cord-254419-qw83atrx	216	59	Complex	Complex	NNP
cord-254419-qw83atrx	216	60	immune	immune	JJ
cord-254419-qw83atrx	216	61	dysregulation	dysregulation	NN
cord-254419-qw83atrx	216	62	in	in	IN
cord-254419-qw83atrx	216	63	COVID-19	covid-19	JJ
cord-254419-qw83atrx	216	64	patients	patient	NNS
cord-254419-qw83atrx	216	65	with	with	IN
cord-254419-qw83atrx	216	66	severe	severe	JJ
cord-254419-qw83atrx	216	67	respiratory	respiratory	JJ
cord-254419-qw83atrx	216	68	failure	failure	NN
cord-254419-qw83atrx	216	69	.	.	.
cord-254419-qw83atrx	217	1	Cell	cell	NN
cord-254419-qw83atrx	217	2	Host	host	NN
cord-254419-qw83atrx	217	3	Microbe	microbe	NN
cord-254419-qw83atrx	217	4	Global	Global	NNP
cord-254419-qw83atrx	217	5	,	,	,
cord-254419-qw83atrx	217	6	regional	regional	JJ
cord-254419-qw83atrx	217	7	,	,	,
cord-254419-qw83atrx	217	8	and	and	CC
cord-254419-qw83atrx	217	9	national	national	JJ
cord-254419-qw83atrx	217	10	estimates	estimate	NNS
cord-254419-qw83atrx	217	11	of	of	IN
cord-254419-qw83atrx	217	12	the	the	DT
cord-254419-qw83atrx	217	13	population	population	NN
cord-254419-qw83atrx	217	14	at	at	IN
cord-254419-qw83atrx	217	15	increased	increase	VBN
cord-254419-qw83atrx	217	16	risk	risk	NN
cord-254419-qw83atrx	217	17	of	of	IN
cord-254419-qw83atrx	217	18	severe	severe	JJ
cord-254419-qw83atrx	217	19	COVID-19	covid-19	NN
cord-254419-qw83atrx	217	20	due	due	IN
cord-254419-qw83atrx	217	21	to	to	IN
cord-254419-qw83atrx	217	22	underlying	underlying	JJ
cord-254419-qw83atrx	217	23	health	health	NN
cord-254419-qw83atrx	217	24	conditions	condition	NNS
cord-254419-qw83atrx	217	25	in	in	IN
cord-254419-qw83atrx	217	26	2020	2020	CD
cord-254419-qw83atrx	217	27	:	:	:
cord-254419-qw83atrx	217	28	a	a	DT
cord-254419-qw83atrx	217	29	modelling	modelling	NN
cord-254419-qw83atrx	217	30	study	study	NN
cord-254419-qw83atrx	218	1	The	the	DT
cord-254419-qw83atrx	218	2	impact	impact	NN
cord-254419-qw83atrx	218	3	of	of	IN
cord-254419-qw83atrx	218	4	ethnicity	ethnicity	NN
cord-254419-qw83atrx	218	5	on	on	IN
cord-254419-qw83atrx	218	6	clinical	clinical	JJ
cord-254419-qw83atrx	218	7	outcomes	outcome	NNS
cord-254419-qw83atrx	218	8	in	in	IN
cord-254419-qw83atrx	218	9	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	218	10	:	:	:
cord-254419-qw83atrx	218	11	a	a	DT
cord-254419-qw83atrx	218	12	systematic	systematic	JJ
cord-254419-qw83atrx	218	13	review	review	NN
cord-254419-qw83atrx	219	1	Genomewide	Genomewide	NNP
cord-254419-qw83atrx	219	2	association	association	NN
cord-254419-qw83atrx	219	3	study	study	NN
cord-254419-qw83atrx	219	4	of	of	IN
cord-254419-qw83atrx	219	5	severe	severe	JJ
cord-254419-qw83atrx	219	6	Covid-19	covid-19	NN
cord-254419-qw83atrx	219	7	with	with	IN
cord-254419-qw83atrx	219	8	respiratory	respiratory	JJ
cord-254419-qw83atrx	219	9	failure	failure	NN
cord-254419-qw83atrx	219	10	Blood	blood	NN
cord-254419-qw83atrx	219	11	type	type	NN
cord-254419-qw83atrx	219	12	and	and	CC
cord-254419-qw83atrx	219	13	outcomes	outcome	NNS
cord-254419-qw83atrx	219	14	in	in	IN
cord-254419-qw83atrx	219	15	patients	patient	NNS
cord-254419-qw83atrx	219	16	with	with	IN
cord-254419-qw83atrx	219	17	COVID-19	covid-19	JJ
cord-254419-qw83atrx	219	18	Endothelial	endothelial	JJ
cord-254419-qw83atrx	219	19	dysfunction	dysfunction	NN
cord-254419-qw83atrx	219	20	in	in	IN
cord-254419-qw83atrx	219	21	sepsis	sepsis	NN
cord-254419-qw83atrx	219	22	Endothelial	endothelial	JJ
cord-254419-qw83atrx	219	23	cell	cell	NN
cord-254419-qw83atrx	219	24	infection	infection	NN
cord-254419-qw83atrx	219	25	and	and	CC
cord-254419-qw83atrx	219	26	endotheliitis	endotheliitis	NN
cord-254419-qw83atrx	219	27	in	in	IN
cord-254419-qw83atrx	219	28	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	219	29	Neutrophil	Neutrophil	NNP
cord-254419-qw83atrx	219	30	extracellular	extracellular	JJ
cord-254419-qw83atrx	219	31	traps	trap	NNS
cord-254419-qw83atrx	219	32	(	(	-LRB-
cord-254419-qw83atrx	219	33	NETs	nets	NN
cord-254419-qw83atrx	219	34	)	)	-RRB-
cord-254419-qw83atrx	220	1	as	as	IN
cord-254419-qw83atrx	220	2	markers	marker	NNS
cord-254419-qw83atrx	220	3	of	of	IN
cord-254419-qw83atrx	220	4	disease	disease	NN
cord-254419-qw83atrx	220	5	severity	severity	NN
cord-254419-qw83atrx	220	6	in	in	IN
cord-254419-qw83atrx	220	7	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	220	8	.	.	.
cord-254419-qw83atrx	221	1	medRxiv	medRxiv	NNP
cord-254419-qw83atrx	221	2	COVID-19-related	covid-19-related	JJ
cord-254419-qw83atrx	221	3	severe	severe	JJ
cord-254419-qw83atrx	221	4	hypercoagulability	hypercoagulability	NN
cord-254419-qw83atrx	221	5	in	in	IN
cord-254419-qw83atrx	221	6	patients	patient	NNS
cord-254419-qw83atrx	221	7	admitted	admit	VBN
cord-254419-qw83atrx	221	8	to	to	IN
cord-254419-qw83atrx	221	9	intensive	intensive	JJ
cord-254419-qw83atrx	221	10	care	care	NN
cord-254419-qw83atrx	221	11	unit	unit	NN
cord-254419-qw83atrx	221	12	for	for	IN
cord-254419-qw83atrx	221	13	acute	acute	JJ
cord-254419-qw83atrx	221	14	respiratory	respiratory	JJ
cord-254419-qw83atrx	221	15	failure	failure	NN
cord-254419-qw83atrx	221	16	Clinical	clinical	JJ
cord-254419-qw83atrx	221	17	course	course	NN
cord-254419-qw83atrx	221	18	and	and	CC
cord-254419-qw83atrx	221	19	risk	risk	NN
cord-254419-qw83atrx	221	20	factors	factor	NNS
cord-254419-qw83atrx	221	21	for	for	IN
cord-254419-qw83atrx	221	22	mortality	mortality	NN
cord-254419-qw83atrx	221	23	of	of	IN
cord-254419-qw83atrx	221	24	adult	adult	NN
cord-254419-qw83atrx	221	25	inpatients	inpatient	NNS
cord-254419-qw83atrx	221	26	with	with	IN
cord-254419-qw83atrx	221	27	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	221	28	in	in	IN
cord-254419-qw83atrx	221	29	Wuhan	Wuhan	NNP
cord-254419-qw83atrx	221	30	,	,	,
cord-254419-qw83atrx	221	31	China	China	NNP
cord-254419-qw83atrx	221	32	:	:	:
cord-254419-qw83atrx	221	33	a	a	DT
cord-254419-qw83atrx	221	34	retrospective	retrospective	JJ
cord-254419-qw83atrx	221	35	cohort	cohort	NN
cord-254419-qw83atrx	221	36	study	study	NN
cord-254419-qw83atrx	221	37	Clinical	clinical	JJ
cord-254419-qw83atrx	221	38	features	feature	NNS
cord-254419-qw83atrx	221	39	of	of	IN
cord-254419-qw83atrx	221	40	patients	patient	NNS
cord-254419-qw83atrx	221	41	infected	infect	VBN
cord-254419-qw83atrx	221	42	with	with	IN
cord-254419-qw83atrx	221	43	2019	2019	CD
cord-254419-qw83atrx	221	44	novel	novel	JJ
cord-254419-qw83atrx	221	45	coronavirus	coronavirus	NN
cord-254419-qw83atrx	221	46	in	in	IN
cord-254419-qw83atrx	221	47	Wuhan	Wuhan	NNP
cord-254419-qw83atrx	221	48	Dysregulated	Dysregulated	NNP
cord-254419-qw83atrx	221	49	type	type	NN
cord-254419-qw83atrx	222	1	I	-PRON-	PRP
cord-254419-qw83atrx	222	2	interferon	interferon	VBD
cord-254419-qw83atrx	222	3	and	and	CC
cord-254419-qw83atrx	222	4	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	222	5	monocyte	monocyte	JJ
cord-254419-qw83atrx	222	6	-	-	HYPH
cord-254419-qw83atrx	222	7	macrophage	macrophage	NN
cord-254419-qw83atrx	222	8	responses	response	NNS
cord-254419-qw83atrx	222	9	cause	cause	VBP
cord-254419-qw83atrx	222	10	lethal	lethal	JJ
cord-254419-qw83atrx	222	11	pneumonia	pneumonia	NN
cord-254419-qw83atrx	222	12	in	in	IN
cord-254419-qw83atrx	222	13	SARS	SARS	NNP
cord-254419-qw83atrx	222	14	-	-	HYPH
cord-254419-qw83atrx	222	15	CoVinfected	CoVinfected	NNP
cord-254419-qw83atrx	222	16	mice	mouse	NNS
cord-254419-qw83atrx	223	1	Should	Should	MD
cord-254419-qw83atrx	223	2	we	-PRON-	PRP
cord-254419-qw83atrx	223	3	stimulate	stimulate	VB
cord-254419-qw83atrx	223	4	or	or	CC
cord-254419-qw83atrx	223	5	suppress	suppress	VB
cord-254419-qw83atrx	224	1	Pulm	Pulm	NNP
cord-254419-qw83atrx	224	2	Ther	Ther	NNP
cord-254419-qw83atrx	224	3	immune	immune	JJ
cord-254419-qw83atrx	224	4	responses	response	NNS
cord-254419-qw83atrx	224	5	in	in	IN
cord-254419-qw83atrx	224	6	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	224	7	?	?	.
cord-254419-qw83atrx	225	1	Cytokine	cytokine	NN
cord-254419-qw83atrx	225	2	and	and	CC
cord-254419-qw83atrx	225	3	anti	anti	JJ
cord-254419-qw83atrx	225	4	-	-	JJ
cord-254419-qw83atrx	225	5	cytokine	cytokine	JJ
cord-254419-qw83atrx	225	6	interventions	intervention	NNS
cord-254419-qw83atrx	225	7	Reduction	reduction	NN
cord-254419-qw83atrx	225	8	and	and	CC
cord-254419-qw83atrx	225	9	functional	functional	JJ
cord-254419-qw83atrx	225	10	exhaustion	exhaustion	NN
cord-254419-qw83atrx	225	11	of	of	IN
cord-254419-qw83atrx	225	12	T	t	NN
cord-254419-qw83atrx	225	13	cells	cell	NNS
cord-254419-qw83atrx	225	14	in	in	IN
cord-254419-qw83atrx	225	15	patients	patient	NNS
cord-254419-qw83atrx	225	16	with	with	IN
cord-254419-qw83atrx	225	17	coronavirus	coronavirus	NN
cord-254419-qw83atrx	225	18	disease	disease	NN
cord-254419-qw83atrx	225	19	2019	2019	CD
cord-254419-qw83atrx	225	20	(	(	-LRB-
cord-254419-qw83atrx	225	21	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	225	22	)	)	-RRB-
cord-254419-qw83atrx	225	23	Dysregulation	Dysregulation	NNP
cord-254419-qw83atrx	225	24	of	of	IN
cord-254419-qw83atrx	225	25	immune	immune	JJ
cord-254419-qw83atrx	225	26	response	response	NN
cord-254419-qw83atrx	225	27	in	in	IN
cord-254419-qw83atrx	225	28	patients	patient	NNS
cord-254419-qw83atrx	225	29	with	with	IN
cord-254419-qw83atrx	225	30	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	225	31	in	in	IN
cord-254419-qw83atrx	225	32	Wuhan	Wuhan	NNP
cord-254419-qw83atrx	225	33	,	,	,
cord-254419-qw83atrx	225	34	China	China	NNP
cord-254419-qw83atrx	225	35	Will	Will	MD
cord-254419-qw83atrx	225	36	complement	complement	VB
cord-254419-qw83atrx	225	37	inhibition	inhibition	NN
cord-254419-qw83atrx	225	38	be	be	VB
cord-254419-qw83atrx	225	39	the	the	DT
cord-254419-qw83atrx	225	40	new	new	JJ
cord-254419-qw83atrx	225	41	target	target	NN
cord-254419-qw83atrx	225	42	in	in	IN
cord-254419-qw83atrx	225	43	treating	treat	VBG
cord-254419-qw83atrx	225	44	COVID-19-related	covid-19-related	JJ
cord-254419-qw83atrx	225	45	systemic	systemic	JJ
cord-254419-qw83atrx	225	46	thrombosis	thrombosis	NN
cord-254419-qw83atrx	225	47	?	?	.
cord-254419-qw83atrx	226	1	Characteristics	characteristic	NNS
cord-254419-qw83atrx	226	2	of	of	IN
cord-254419-qw83atrx	226	3	peripheral	peripheral	JJ
cord-254419-qw83atrx	226	4	lymphocyte	lymphocyte	NN
cord-254419-qw83atrx	226	5	subset	subset	VBN
cord-254419-qw83atrx	226	6	alteration	alteration	NN
cord-254419-qw83atrx	226	7	in	in	IN
cord-254419-qw83atrx	226	8	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	226	9	pneumonia	pneumonia	NN
cord-254419-qw83atrx	226	10	Coagulopathy	Coagulopathy	NNP
cord-254419-qw83atrx	226	11	of	of	IN
cord-254419-qw83atrx	226	12	coronavirus	coronavirus	NN
cord-254419-qw83atrx	226	13	disease	disease	NN
cord-254419-qw83atrx	226	14	2019	2019	CD
cord-254419-qw83atrx	227	1	COVID-19	covid-19	VB
cord-254419-qw83atrx	227	2	and	and	CC
cord-254419-qw83atrx	227	3	its	-PRON-	PRP$
cord-254419-qw83atrx	227	4	implications	implication	NNS
cord-254419-qw83atrx	227	5	for	for	IN
cord-254419-qw83atrx	227	6	thrombosis	thrombosis	NN
cord-254419-qw83atrx	227	7	and	and	CC
cord-254419-qw83atrx	227	8	anticoagulation	anticoagulation	NN
cord-254419-qw83atrx	227	9	Abnormal	abnormal	JJ
cord-254419-qw83atrx	227	10	coagulation	coagulation	NN
cord-254419-qw83atrx	227	11	parameters	parameter	NNS
cord-254419-qw83atrx	227	12	are	be	VBP
cord-254419-qw83atrx	227	13	associated	associate	VBN
cord-254419-qw83atrx	227	14	with	with	IN
cord-254419-qw83atrx	227	15	poor	poor	JJ
cord-254419-qw83atrx	227	16	prognosis	prognosis	NN
cord-254419-qw83atrx	227	17	in	in	IN
cord-254419-qw83atrx	227	18	patients	patient	NNS
cord-254419-qw83atrx	227	19	with	with	IN
cord-254419-qw83atrx	227	20	novel	novel	JJ
cord-254419-qw83atrx	227	21	coronavirus	coronavirus	NN
cord-254419-qw83atrx	227	22	pneumonia	pneumonia	NN
cord-254419-qw83atrx	227	23	Epidemiological	epidemiological	JJ
cord-254419-qw83atrx	227	24	and	and	CC
cord-254419-qw83atrx	227	25	clinical	clinical	JJ
cord-254419-qw83atrx	227	26	characteristics	characteristic	NNS
cord-254419-qw83atrx	227	27	of	of	IN
cord-254419-qw83atrx	227	28	99	99	CD
cord-254419-qw83atrx	227	29	cases	case	NNS
cord-254419-qw83atrx	227	30	of	of	IN
cord-254419-qw83atrx	227	31	2019	2019	CD
cord-254419-qw83atrx	227	32	novel	novel	JJ
cord-254419-qw83atrx	227	33	coronavirus	coronavirus	NN
cord-254419-qw83atrx	227	34	pneumonia	pneumonia	NN
cord-254419-qw83atrx	227	35	in	in	IN
cord-254419-qw83atrx	227	36	Wuhan	Wuhan	NNP
cord-254419-qw83atrx	227	37	,	,	,
cord-254419-qw83atrx	227	38	China	China	NNP
cord-254419-qw83atrx	227	39	:	:	:
cord-254419-qw83atrx	227	40	a	a	DT
cord-254419-qw83atrx	227	41	descriptive	descriptive	JJ
cord-254419-qw83atrx	227	42	study	study	NN
cord-254419-qw83atrx	227	43	Clinical	clinical	JJ
cord-254419-qw83atrx	227	44	characteristics	characteristic	NNS
cord-254419-qw83atrx	227	45	of	of	IN
cord-254419-qw83atrx	227	46	coronavirus	coronavirus	NN
cord-254419-qw83atrx	227	47	disease	disease	NN
cord-254419-qw83atrx	227	48	2019	2019	CD
cord-254419-qw83atrx	227	49	in	in	IN
cord-254419-qw83atrx	227	50	China	China	NNP
cord-254419-qw83atrx	227	51	Thrombocytopenia	Thrombocytopenia	NNP
cord-254419-qw83atrx	227	52	is	be	VBZ
cord-254419-qw83atrx	227	53	associated	associate	VBN
cord-254419-qw83atrx	227	54	with	with	IN
cord-254419-qw83atrx	227	55	severe	severe	JJ
cord-254419-qw83atrx	227	56	coronavirus	coronavirus	NN
cord-254419-qw83atrx	227	57	disease	disease	NN
cord-254419-qw83atrx	227	58	2019	2019	CD
cord-254419-qw83atrx	227	59	(	(	-LRB-
cord-254419-qw83atrx	227	60	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	227	61	)	)	-RRB-
cord-254419-qw83atrx	227	62	infections	infection	NNS
cord-254419-qw83atrx	227	63	:	:	:
cord-254419-qw83atrx	227	64	a	a	DT
cord-254419-qw83atrx	227	65	meta	meta	JJ
cord-254419-qw83atrx	227	66	-	-	HYPH
cord-254419-qw83atrx	227	67	analysis	analysis	NN
cord-254419-qw83atrx	227	68	Thrombocytopenia	Thrombocytopenia	NNP
cord-254419-qw83atrx	227	69	and	and	CC
cord-254419-qw83atrx	227	70	its	-PRON-	PRP$
cord-254419-qw83atrx	227	71	association	association	NN
cord-254419-qw83atrx	227	72	with	with	IN
cord-254419-qw83atrx	227	73	mortality	mortality	NN
cord-254419-qw83atrx	227	74	in	in	IN
cord-254419-qw83atrx	227	75	patients	patient	NNS
cord-254419-qw83atrx	227	76	with	with	IN
cord-254419-qw83atrx	227	77	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	227	78	.	.	.
cord-254419-qw83atrx	228	1	J	J	NNP
cord-254419-qw83atrx	228	2	Thromb	Thromb	NNP
cord-254419-qw83atrx	228	3	Haemost	Haemost	NNP
cord-254419-qw83atrx	229	1	Critically	critically	RB
cord-254419-qw83atrx	229	2	ill	ill	RB
cord-254419-qw83atrx	229	3	COVID-19	covid-19	CD
cord-254419-qw83atrx	229	4	infected	infected	JJ
cord-254419-qw83atrx	229	5	patients	patient	NNS
cord-254419-qw83atrx	229	6	exhibit	exhibit	VBP
cord-254419-qw83atrx	229	7	increased	increase	VBN
cord-254419-qw83atrx	229	8	clot	clot	NN
cord-254419-qw83atrx	229	9	waveform	waveform	NN
cord-254419-qw83atrx	229	10	analysis	analysis	NN
cord-254419-qw83atrx	229	11	parameters	parameter	NNS
cord-254419-qw83atrx	229	12	consistent	consistent	JJ
cord-254419-qw83atrx	229	13	with	with	IN
cord-254419-qw83atrx	229	14	hypercoagulability	hypercoagulability	NNP
cord-254419-qw83atrx	229	15	Hypercoagulability	Hypercoagulability	NNP
cord-254419-qw83atrx	229	16	of	of	IN
cord-254419-qw83atrx	229	17	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	229	18	patients	patient	NNS
cord-254419-qw83atrx	229	19	in	in	IN
cord-254419-qw83atrx	229	20	intensive	intensive	JJ
cord-254419-qw83atrx	229	21	care	care	NN
cord-254419-qw83atrx	229	22	unit	unit	NN
cord-254419-qw83atrx	229	23	.	.	.
cord-254419-qw83atrx	230	1	A	a	DT
cord-254419-qw83atrx	230	2	report	report	NN
cord-254419-qw83atrx	230	3	of	of	IN
cord-254419-qw83atrx	230	4	thromboelastography	thromboelastography	NNP
cord-254419-qw83atrx	230	5	findings	finding	NNS
cord-254419-qw83atrx	230	6	and	and	CC
cord-254419-qw83atrx	230	7	other	other	JJ
cord-254419-qw83atrx	230	8	parameters	parameter	NNS
cord-254419-qw83atrx	230	9	of	of	IN
cord-254419-qw83atrx	230	10	hemostasis	hemostasis	NN
cord-254419-qw83atrx	230	11	Fibrinolysis	Fibrinolysis	NNP
cord-254419-qw83atrx	230	12	shutdown	shutdown	NN
cord-254419-qw83atrx	230	13	correlation	correlation	NN
cord-254419-qw83atrx	230	14	with	with	IN
cord-254419-qw83atrx	230	15	thromboembolic	thromboembolic	JJ
cord-254419-qw83atrx	230	16	events	event	NNS
cord-254419-qw83atrx	230	17	in	in	IN
cord-254419-qw83atrx	230	18	severe	severe	JJ
cord-254419-qw83atrx	230	19	COVID-19	covid-19	CD
cord-254419-qw83atrx	230	20	infection	infection	NN
cord-254419-qw83atrx	230	21	High	high	JJ
cord-254419-qw83atrx	230	22	incidence	incidence	NN
cord-254419-qw83atrx	230	23	of	of	IN
cord-254419-qw83atrx	230	24	venous	venous	JJ
cord-254419-qw83atrx	230	25	thromboembolic	thromboembolic	JJ
cord-254419-qw83atrx	230	26	events	event	NNS
cord-254419-qw83atrx	230	27	in	in	IN
cord-254419-qw83atrx	230	28	anticoagulated	anticoagulated	JJ
cord-254419-qw83atrx	230	29	severe	severe	JJ
cord-254419-qw83atrx	230	30	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	230	31	patients	patient	NNS
cord-254419-qw83atrx	230	32	Incidence	incidence	NN
cord-254419-qw83atrx	230	33	of	of	IN
cord-254419-qw83atrx	230	34	thrombotic	thrombotic	JJ
cord-254419-qw83atrx	230	35	complications	complication	NNS
cord-254419-qw83atrx	230	36	in	in	IN
cord-254419-qw83atrx	230	37	critically	critically	RB
cord-254419-qw83atrx	230	38	ill	ill	JJ
cord-254419-qw83atrx	230	39	ICU	ICU	NNP
cord-254419-qw83atrx	230	40	patients	patient	NNS
cord-254419-qw83atrx	230	41	with	with	IN
cord-254419-qw83atrx	230	42	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	230	43	Confirmation	Confirmation	NNP
cord-254419-qw83atrx	230	44	of	of	IN
cord-254419-qw83atrx	230	45	the	the	DT
cord-254419-qw83atrx	230	46	high	high	JJ
cord-254419-qw83atrx	230	47	cumulative	cumulative	JJ
cord-254419-qw83atrx	230	48	incidence	incidence	NN
cord-254419-qw83atrx	230	49	of	of	IN
cord-254419-qw83atrx	230	50	thrombotic	thrombotic	JJ
cord-254419-qw83atrx	230	51	complications	complication	NNS
cord-254419-qw83atrx	230	52	in	in	IN
cord-254419-qw83atrx	230	53	critically	critically	RB
cord-254419-qw83atrx	230	54	ill	ill	JJ
cord-254419-qw83atrx	230	55	ICU	ICU	NNP
cord-254419-qw83atrx	230	56	patients	patient	NNS
cord-254419-qw83atrx	230	57	with	with	IN
cord-254419-qw83atrx	230	58	COVID-19	covid-19	NN
cord-254419-qw83atrx	230	59	:	:	:
cord-254419-qw83atrx	230	60	An	an	DT
cord-254419-qw83atrx	230	61	updated	update	VBN
cord-254419-qw83atrx	230	62	analysis	analysis	NN
cord-254419-qw83atrx	231	1	Lupus	lupus	JJ
cord-254419-qw83atrx	231	2	anticoagulant	anticoagulant	NN
cord-254419-qw83atrx	231	3	is	be	VBZ
cord-254419-qw83atrx	231	4	frequent	frequent	JJ
cord-254419-qw83atrx	231	5	in	in	IN
cord-254419-qw83atrx	231	6	patients	patient	NNS
cord-254419-qw83atrx	231	7	with	with	IN
cord-254419-qw83atrx	231	8	Covid-19	Covid-19	NNP
cord-254419-qw83atrx	231	9	Venous	venous	JJ
cord-254419-qw83atrx	231	10	thrombosis	thrombosis	NN
cord-254419-qw83atrx	231	11	and	and	CC
cord-254419-qw83atrx	231	12	arteriosclerosis	arteriosclerosis	NN
cord-254419-qw83atrx	231	13	obliterans	obliteran	NNS
cord-254419-qw83atrx	231	14	of	of	IN
cord-254419-qw83atrx	231	15	lower	low	JJR
cord-254419-qw83atrx	231	16	extremities	extremity	NNS
cord-254419-qw83atrx	231	17	in	in	IN
cord-254419-qw83atrx	231	18	a	a	DT
cord-254419-qw83atrx	231	19	very	very	RB
cord-254419-qw83atrx	231	20	severe	severe	JJ
cord-254419-qw83atrx	231	21	patient	patient	NN
cord-254419-qw83atrx	231	22	with	with	IN
cord-254419-qw83atrx	231	23	2019	2019	CD
cord-254419-qw83atrx	231	24	novel	novel	JJ
cord-254419-qw83atrx	231	25	coronavirus	coronavirus	NN
cord-254419-qw83atrx	231	26	disease	disease	NN
cord-254419-qw83atrx	231	27	:	:	:
cord-254419-qw83atrx	231	28	a	a	DT
cord-254419-qw83atrx	231	29	case	case	NN
cord-254419-qw83atrx	231	30	report	report	NN
cord-254419-qw83atrx	231	31	Complement	complement	NN
cord-254419-qw83atrx	231	32	-	-	HYPH
cord-254419-qw83atrx	231	33	associated	associate	VBN
cord-254419-qw83atrx	231	34	microvascular	microvascular	JJ
cord-254419-qw83atrx	231	35	injury	injury	NN
cord-254419-qw83atrx	231	36	and	and	CC
cord-254419-qw83atrx	231	37	thrombosis	thrombosis	NN
cord-254419-qw83atrx	231	38	in	in	IN
cord-254419-qw83atrx	231	39	the	the	DT
cord-254419-qw83atrx	231	40	pathogenesis	pathogenesis	NN
cord-254419-qw83atrx	231	41	of	of	IN
cord-254419-qw83atrx	231	42	severe	severe	JJ
cord-254419-qw83atrx	231	43	COVID-19	covid-19	JJ
cord-254419-qw83atrx	231	44	infection	infection	NN
cord-254419-qw83atrx	231	45	:	:	:
cord-254419-qw83atrx	231	46	a	a	DT
cord-254419-qw83atrx	231	47	report	report	NN
cord-254419-qw83atrx	231	48	of	of	IN
cord-254419-qw83atrx	231	49	five	five	CD
cord-254419-qw83atrx	231	50	cases	case	NNS
cord-254419-qw83atrx	231	51	Pathological	pathological	JJ
cord-254419-qw83atrx	231	52	evidence	evidence	NN
cord-254419-qw83atrx	231	53	of	of	IN
cord-254419-qw83atrx	231	54	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	231	55	thrombotic	thrombotic	JJ
cord-254419-qw83atrx	231	56	phenomena	phenomenon	NNS
cord-254419-qw83atrx	231	57	in	in	IN
cord-254419-qw83atrx	231	58	severe	severe	JJ
cord-254419-qw83atrx	231	59	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	231	60	Acute	acute	JJ
cord-254419-qw83atrx	231	61	pulmonary	pulmonary	JJ
cord-254419-qw83atrx	231	62	embolism	embolism	NN
cord-254419-qw83atrx	231	63	and	and	CC
cord-254419-qw83atrx	231	64	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	231	65	pneumonia	pneumonia	NN
cord-254419-qw83atrx	231	66	:	:	:
cord-254419-qw83atrx	231	67	a	a	DT
cord-254419-qw83atrx	231	68	random	random	JJ
cord-254419-qw83atrx	231	69	association	association	NN
cord-254419-qw83atrx	231	70	?	?	.
cord-254419-qw83atrx	232	1	ISTH	isth	JJ
cord-254419-qw83atrx	232	2	interim	interim	JJ
cord-254419-qw83atrx	232	3	guidance	guidance	NN
cord-254419-qw83atrx	232	4	on	on	IN
cord-254419-qw83atrx	232	5	recognition	recognition	NN
cord-254419-qw83atrx	232	6	and	and	CC
cord-254419-qw83atrx	232	7	management	management	NN
cord-254419-qw83atrx	232	8	of	of	IN
cord-254419-qw83atrx	232	9	coagulopathy	coagulopathy	NN
cord-254419-qw83atrx	232	10	in	in	IN
cord-254419-qw83atrx	232	11	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	232	12	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	232	13	and	and	CC
cord-254419-qw83atrx	232	14	thrombotic	thrombotic	JJ
cord-254419-qw83atrx	232	15	or	or	CC
cord-254419-qw83atrx	232	16	thromboembolic	thromboembolic	JJ
cord-254419-qw83atrx	232	17	disease	disease	NN
cord-254419-qw83atrx	232	18	:	:	:
cord-254419-qw83atrx	232	19	implications	implication	NNS
cord-254419-qw83atrx	232	20	for	for	IN
cord-254419-qw83atrx	232	21	prevention	prevention	NN
cord-254419-qw83atrx	232	22	,	,	,
cord-254419-qw83atrx	232	23	antithrombotic	antithrombotic	JJ
cord-254419-qw83atrx	232	24	therapy	therapy	NN
cord-254419-qw83atrx	232	25	,	,	,
cord-254419-qw83atrx	232	26	and	and	CC
cord-254419-qw83atrx	232	27	follow	follow	NN
cord-254419-qw83atrx	232	28	-	-	HYPH
cord-254419-qw83atrx	232	29	Up	up	NN
cord-254419-qw83atrx	232	30	:	:	:
cord-254419-qw83atrx	233	1	JACC	JACC	NNP
cord-254419-qw83atrx	233	2	state	state	NN
cord-254419-qw83atrx	233	3	-	-	HYPH
cord-254419-qw83atrx	233	4	of	of	IN
cord-254419-qw83atrx	233	5	-	-	HYPH
cord-254419-qw83atrx	233	6	the	the	DT
cord-254419-qw83atrx	233	7	-	-	HYPH
cord-254419-qw83atrx	233	8	art	art	NN
cord-254419-qw83atrx	233	9	review	review	NN
cord-254419-qw83atrx	233	10	ISTH	ISTH	NNP
cord-254419-qw83atrx	233	11	interim	interim	JJ
cord-254419-qw83atrx	233	12	guidance	guidance	NN
cord-254419-qw83atrx	233	13	on	on	IN
cord-254419-qw83atrx	233	14	recognition	recognition	NN
cord-254419-qw83atrx	233	15	and	and	CC
cord-254419-qw83atrx	233	16	management	management	NN
cord-254419-qw83atrx	233	17	of	of	IN
cord-254419-qw83atrx	233	18	coagulopathy	coagulopathy	NN
cord-254419-qw83atrx	233	19	in	in	IN
cord-254419-qw83atrx	233	20	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	233	21	:	:	:
cord-254419-qw83atrx	233	22	a	a	DT
cord-254419-qw83atrx	233	23	comment	comment	NN
cord-254419-qw83atrx	233	24	Fibrinolytic	Fibrinolytic	NNP
cord-254419-qw83atrx	233	25	abnormalities	abnormality	NNS
cord-254419-qw83atrx	233	26	in	in	IN
cord-254419-qw83atrx	233	27	acute	acute	JJ
cord-254419-qw83atrx	233	28	respiratory	respiratory	JJ
cord-254419-qw83atrx	233	29	distress	distress	NN
cord-254419-qw83atrx	233	30	syndrome	syndrome	NN
cord-254419-qw83atrx	233	31	(	(	-LRB-
cord-254419-qw83atrx	233	32	ARDS	ARDS	NNP
cord-254419-qw83atrx	233	33	)	)	-RRB-
cord-254419-qw83atrx	233	34	and	and	CC
cord-254419-qw83atrx	233	35	versatility	versatility	NN
cord-254419-qw83atrx	233	36	of	of	IN
cord-254419-qw83atrx	233	37	thrombolytic	thrombolytic	NN
cord-254419-qw83atrx	233	38	drugs	drug	NNS
cord-254419-qw83atrx	233	39	to	to	TO
cord-254419-qw83atrx	233	40	treat	treat	VB
cord-254419-qw83atrx	233	41	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	233	42	Pulmonary	pulmonary	JJ
cord-254419-qw83atrx	233	43	pathology	pathology	NN
cord-254419-qw83atrx	233	44	of	of	IN
cord-254419-qw83atrx	233	45	early	early	JJ
cord-254419-qw83atrx	233	46	-	-	HYPH
cord-254419-qw83atrx	233	47	phase	phase	NN
cord-254419-qw83atrx	233	48	2019	2019	CD
cord-254419-qw83atrx	233	49	novel	novel	NN
cord-254419-qw83atrx	233	50	coronavirus	coronavirus	NN
cord-254419-qw83atrx	233	51	(	(	-LRB-
cord-254419-qw83atrx	233	52	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	233	53	)	)	-RRB-
cord-254419-qw83atrx	233	54	pneumonia	pneumonia	NN
cord-254419-qw83atrx	233	55	in	in	IN
cord-254419-qw83atrx	233	56	two	two	CD
cord-254419-qw83atrx	233	57	patients	patient	NNS
cord-254419-qw83atrx	233	58	with	with	IN
cord-254419-qw83atrx	233	59	lung	lung	NN
cord-254419-qw83atrx	233	60	cancer	cancer	NN
cord-254419-qw83atrx	233	61	Tissue	Tissue	NNP
cord-254419-qw83atrx	233	62	plasminogen	plasminogen	NN
cord-254419-qw83atrx	233	63	activator	activator	NN
cord-254419-qw83atrx	233	64	(	(	-LRB-
cord-254419-qw83atrx	233	65	tPA	tPA	NNP
cord-254419-qw83atrx	233	66	)	)	-RRB-
cord-254419-qw83atrx	233	67	treatment	treatment	NN
cord-254419-qw83atrx	233	68	for	for	IN
cord-254419-qw83atrx	233	69	COVID-19-associated	covid-19-associated	JJ
cord-254419-qw83atrx	233	70	acute	acute	JJ
cord-254419-qw83atrx	233	71	respiratory	respiratory	JJ
cord-254419-qw83atrx	233	72	distress	distress	NN
cord-254419-qw83atrx	233	73	syndrome	syndrome	NN
cord-254419-qw83atrx	233	74	(	(	-LRB-
cord-254419-qw83atrx	233	75	ARDS	ARDS	NNP
cord-254419-qw83atrx	233	76	)	)	-RRB-
cord-254419-qw83atrx	233	77	:	:	:
cord-254419-qw83atrx	233	78	a	a	DT
cord-254419-qw83atrx	233	79	case	case	NN
cord-254419-qw83atrx	233	80	series	series	NN
cord-254419-qw83atrx	233	81	RECOVERY	recovery	NN
cord-254419-qw83atrx	233	82	trial	trial	NN
cord-254419-qw83atrx	233	83	:	:	:
cord-254419-qw83atrx	234	1	the	the	DT
cord-254419-qw83atrx	234	2	UK	UK	NNP
cord-254419-qw83atrx	234	3	covid-19	covid-19	NNP
cord-254419-qw83atrx	234	4	study	study	NN
cord-254419-qw83atrx	234	5	resetting	reset	VBG
cord-254419-qw83atrx	234	6	expectations	expectation	NNS
cord-254419-qw83atrx	234	7	for	for	IN
cord-254419-qw83atrx	234	8	clinical	clinical	JJ
cord-254419-qw83atrx	234	9	trials	trial	NNS
cord-254419-qw83atrx	234	10	Diagnostic	diagnostic	JJ
cord-254419-qw83atrx	234	11	utility	utility	NN
cord-254419-qw83atrx	234	12	of	of	IN
cord-254419-qw83atrx	234	13	clinical	clinical	JJ
cord-254419-qw83atrx	234	14	laboratory	laboratory	NN
cord-254419-qw83atrx	234	15	data	datum	NNS
cord-254419-qw83atrx	234	16	determinations	determination	NNS
cord-254419-qw83atrx	234	17	for	for	IN
cord-254419-qw83atrx	234	18	patients	patient	NNS
cord-254419-qw83atrx	234	19	with	with	IN
cord-254419-qw83atrx	234	20	the	the	DT
cord-254419-qw83atrx	234	21	severe	severe	JJ
cord-254419-qw83atrx	234	22	COVID-19	covid-19	NN
cord-254419-qw83atrx	235	1	Can	Can	MD
cord-254419-qw83atrx	235	2	we	-PRON-	PRP
cord-254419-qw83atrx	235	3	use	use	VB
cord-254419-qw83atrx	235	4	interleukin-6	interleukin-6	NNP
cord-254419-qw83atrx	235	5	(	(	-LRB-
cord-254419-qw83atrx	235	6	IL-6	IL-6	NNP
cord-254419-qw83atrx	235	7	)	)	-RRB-
cord-254419-qw83atrx	235	8	blockade	blockade	NN
cord-254419-qw83atrx	235	9	for	for	IN
cord-254419-qw83atrx	235	10	coronavirus	coronavirus	NN
cord-254419-qw83atrx	235	11	disease	disease	NN
cord-254419-qw83atrx	235	12	(	(	-LRB-
cord-254419-qw83atrx	235	13	COVID-19)-induced	covid-19)-induce	VBN
cord-254419-qw83atrx	235	14	cytokine	cytokine	NN
cord-254419-qw83atrx	235	15	release	release	NN
cord-254419-qw83atrx	235	16	syndrome	syndrome	NN
cord-254419-qw83atrx	235	17	(	(	-LRB-
cord-254419-qw83atrx	235	18	CRS	CRS	NNP
cord-254419-qw83atrx	235	19	)	)	-RRB-
cord-254419-qw83atrx	235	20	?	?	.
cord-254419-qw83atrx	236	1	Tocilizumab	Tocilizumab	NNP
cord-254419-qw83atrx	236	2	:	:	:
cord-254419-qw83atrx	236	3	a	a	DT
cord-254419-qw83atrx	236	4	review	review	NN
cord-254419-qw83atrx	236	5	in	in	IN
cord-254419-qw83atrx	236	6	rheumatoid	rheumatoid	NN
cord-254419-qw83atrx	236	7	arthritis	arthritis	NN
cord-254419-qw83atrx	237	1	Why	why	WRB
cord-254419-qw83atrx	237	2	tocilizumab	tocilizumab	NN
cord-254419-qw83atrx	237	3	could	could	MD
cord-254419-qw83atrx	237	4	be	be	VB
cord-254419-qw83atrx	237	5	an	an	DT
cord-254419-qw83atrx	237	6	effective	effective	JJ
cord-254419-qw83atrx	237	7	treatment	treatment	NN
cord-254419-qw83atrx	237	8	for	for	IN
cord-254419-qw83atrx	237	9	severe	severe	JJ
cord-254419-qw83atrx	237	10	COVID-19	covid-19	NN
cord-254419-qw83atrx	237	11	?	?	.
cord-254419-qw83atrx	237	12	High	high	JJ
cord-254419-qw83atrx	237	13	-	-	HYPH
cord-254419-qw83atrx	237	14	dose	dose	NN
cord-254419-qw83atrx	237	15	intravenous	intravenous	JJ
cord-254419-qw83atrx	237	16	immunoglobulin	immunoglobulin	NN
cord-254419-qw83atrx	237	17	as	as	IN
cord-254419-qw83atrx	237	18	a	a	DT
cord-254419-qw83atrx	237	19	therapeutic	therapeutic	JJ
cord-254419-qw83atrx	237	20	option	option	NN
cord-254419-qw83atrx	237	21	for	for	IN
cord-254419-qw83atrx	237	22	deteriorating	deteriorate	VBG
cord-254419-qw83atrx	237	23	patients	patient	NNS
cord-254419-qw83atrx	237	24	with	with	IN
cord-254419-qw83atrx	237	25	coronavirus	coronavirus	NN
cord-254419-qw83atrx	237	26	disease	disease	NN
cord-254419-qw83atrx	237	27	2019	2019	CD
cord-254419-qw83atrx	238	1	Are	be	VBP
cord-254419-qw83atrx	238	2	patients	patient	NNS
cord-254419-qw83atrx	238	3	with	with	IN
cord-254419-qw83atrx	238	4	hypertension	hypertension	NN
cord-254419-qw83atrx	238	5	and	and	CC
cord-254419-qw83atrx	238	6	diabetes	diabetes	NN
cord-254419-qw83atrx	238	7	mellitus	mellitus	NN
cord-254419-qw83atrx	238	8	at	at	IN
cord-254419-qw83atrx	238	9	increased	increase	VBN
cord-254419-qw83atrx	238	10	risk	risk	NN
cord-254419-qw83atrx	238	11	for	for	IN
cord-254419-qw83atrx	238	12	COVID-19	covid-19	JJ
cord-254419-qw83atrx	238	13	infection	infection	NN
cord-254419-qw83atrx	238	14	?	?	.
cord-254419-qw83atrx	239	1	EMA	EMA	NNP
cord-254419-qw83atrx	239	2	advice	advice	NN
cord-254419-qw83atrx	239	3	on	on	IN
cord-254419-qw83atrx	239	4	the	the	DT
cord-254419-qw83atrx	239	5	use	use	NN
cord-254419-qw83atrx	239	6	of	of	IN
cord-254419-qw83atrx	239	7	NSAIDs	NSAIDs	NNP
cord-254419-qw83atrx	239	8	for	for	IN
cord-254419-qw83atrx	239	9	Covid-19	Covid-19	NNP
cord-254419-qw83atrx	239	10	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	239	11	:	:	:
cord-254419-qw83atrx	239	12	combining	combine	VBG
cord-254419-qw83atrx	239	13	antiviral	antiviral	JJ
cord-254419-qw83atrx	239	14	and	and	CC
cord-254419-qw83atrx	239	15	anti	anti	JJ
cord-254419-qw83atrx	239	16	-	-	JJ
cord-254419-qw83atrx	239	17	inflammatory	inflammatory	JJ
cord-254419-qw83atrx	239	18	treatments	treatment	NNS
cord-254419-qw83atrx	239	19	Baricitinib	Baricitinib	NNP
cord-254419-qw83atrx	239	20	as	as	IN
cord-254419-qw83atrx	239	21	potential	potential	JJ
cord-254419-qw83atrx	239	22	treatment	treatment	NN
cord-254419-qw83atrx	239	23	for	for	IN
cord-254419-qw83atrx	239	24	2019-nCoV	2019-ncov	CD
cord-254419-qw83atrx	239	25	acute	acute	JJ
cord-254419-qw83atrx	239	26	respiratory	respiratory	JJ
cord-254419-qw83atrx	239	27	disease	disease	NN
cord-254419-qw83atrx	240	1	In	in	IN
cord-254419-qw83atrx	240	2	-	-	HYPH
cord-254419-qw83atrx	240	3	hospital	hospital	NN
cord-254419-qw83atrx	240	4	use	use	NN
cord-254419-qw83atrx	240	5	of	of	IN
cord-254419-qw83atrx	240	6	statins	statin	NNS
cord-254419-qw83atrx	240	7	is	be	VBZ
cord-254419-qw83atrx	240	8	associated	associate	VBN
cord-254419-qw83atrx	240	9	with	with	IN
cord-254419-qw83atrx	240	10	a	a	DT
cord-254419-qw83atrx	240	11	reduced	reduce	VBN
cord-254419-qw83atrx	240	12	risk	risk	NN
cord-254419-qw83atrx	240	13	of	of	IN
cord-254419-qw83atrx	240	14	mortality	mortality	NN
cord-254419-qw83atrx	240	15	among	among	IN
cord-254419-qw83atrx	240	16	individuals	individual	NNS
cord-254419-qw83atrx	240	17	with	with	IN
cord-254419-qw83atrx	240	18	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	240	19	Convalescent	Convalescent	NNP
cord-254419-qw83atrx	240	20	plasma	plasma	NN
cord-254419-qw83atrx	240	21	:	:	:
cord-254419-qw83atrx	240	22	new	new	JJ
cord-254419-qw83atrx	240	23	evidence	evidence	NN
cord-254419-qw83atrx	240	24	for	for	IN
cord-254419-qw83atrx	240	25	an	an	DT
cord-254419-qw83atrx	240	26	old	old	JJ
cord-254419-qw83atrx	240	27	therapeutic	therapeutic	JJ
cord-254419-qw83atrx	240	28	tool	tool	NN
cord-254419-qw83atrx	240	29	?	?	.
cord-254419-qw83atrx	241	1	Convalescent	convalescent	JJ
cord-254419-qw83atrx	241	2	plasma	plasma	NN
cord-254419-qw83atrx	241	3	or	or	CC
cord-254419-qw83atrx	241	4	hyperimmune	hyperimmune	NN
cord-254419-qw83atrx	241	5	immunoglobulin	immunoglobulin	NN
cord-254419-qw83atrx	241	6	for	for	IN
cord-254419-qw83atrx	241	7	people	people	NNS
cord-254419-qw83atrx	241	8	with	with	IN
cord-254419-qw83atrx	241	9	COVID-19	COVID-19	NNP
cord-254419-qw83atrx	241	10	:	:	:
cord-254419-qw83atrx	241	11	a	a	DT
cord-254419-qw83atrx	241	12	living	live	VBG
cord-254419-qw83atrx	241	13	systematic	systematic	JJ
cord-254419-qw83atrx	241	14	review	review	NN