id sid tid token lemma pos cord-253746-15w4gquq 1 1 key key JJ cord-253746-15w4gquq 1 2 : : : cord-253746-15w4gquq 1 3 cord-253746 cord-253746 NNP cord-253746-15w4gquq 1 4 - - HYPH cord-253746-15w4gquq 1 5 15w4gquq 15w4gquq CD cord-253746-15w4gquq 1 6 authors author NNS cord-253746-15w4gquq 1 7 : : : cord-253746-15w4gquq 1 8 Goldman Goldman NNP cord-253746-15w4gquq 1 9 , , , cord-253746-15w4gquq 1 10 Michel Michel NNP cord-253746-15w4gquq 1 11 ; ; : cord-253746-15w4gquq 1 12 Silva Silva NNP cord-253746-15w4gquq 1 13 , , , cord-253746-15w4gquq 1 14 Mitchell Mitchell NNP cord-253746-15w4gquq 1 15 title title NN cord-253746-15w4gquq 1 16 : : : cord-253746-15w4gquq 1 17 Reflections reflection NNS cord-253746-15w4gquq 1 18 on on IN cord-253746-15w4gquq 1 19 the the DT cord-253746-15w4gquq 1 20 Collaborative Collaborative NNP cord-253746-15w4gquq 1 21 Fight Fight NNP cord-253746-15w4gquq 2 1 Against against IN cord-253746-15w4gquq 2 2 COVID-19 covid-19 CD cord-253746-15w4gquq 2 3 date date NN cord-253746-15w4gquq 2 4 : : : cord-253746-15w4gquq 2 5 2020 2020 CD cord-253746-15w4gquq 2 6 - - HYPH cord-253746-15w4gquq 2 7 09 09 CD cord-253746-15w4gquq 2 8 - - SYM cord-253746-15w4gquq 2 9 17 17 CD cord-253746-15w4gquq 2 10 journal journal NN cord-253746-15w4gquq 2 11 : : : cord-253746-15w4gquq 3 1 Front Front NNP cord-253746-15w4gquq 3 2 Med Med NNP cord-253746-15w4gquq 3 3 ( ( -LRB- cord-253746-15w4gquq 3 4 Lausanne Lausanne NNP cord-253746-15w4gquq 3 5 ) ) -RRB- cord-253746-15w4gquq 3 6 DOI DOI NNP cord-253746-15w4gquq 3 7 : : : cord-253746-15w4gquq 4 1 10.3389 10.3389 CD cord-253746-15w4gquq 4 2 / / SYM cord-253746-15w4gquq 4 3 fmed.2020.00565 fmed.2020.00565 NNS cord-253746-15w4gquq 4 4 sha sha NNP cord-253746-15w4gquq 4 5 : : : cord-253746-15w4gquq 4 6 5e1fd8235fab26c9a799af0298a09e10e25f9c10 5e1fd8235fab26c9a799af0298a09e10e25f9c10 CD cord-253746-15w4gquq 4 7 doc_id doc_id CD cord-253746-15w4gquq 4 8 : : : cord-253746-15w4gquq 5 1 253746 253746 CD cord-253746-15w4gquq 5 2 cord_uid cord_uid NNS cord-253746-15w4gquq 5 3 : : : cord-253746-15w4gquq 6 1 15w4gquq 15w4gquq CD cord-253746-15w4gquq 6 2 Clinical clinical JJ cord-253746-15w4gquq 6 3 trials trial NNS cord-253746-15w4gquq 6 4 to to TO cord-253746-15w4gquq 6 5 identify identify VB cord-253746-15w4gquq 6 6 efficient efficient JJ cord-253746-15w4gquq 6 7 treatments treatment NNS cord-253746-15w4gquq 6 8 against against IN cord-253746-15w4gquq 6 9 COVID-19 covid-19 JJ cord-253746-15w4gquq 6 10 flourish flourish NN cord-253746-15w4gquq 6 11 worldwide worldwide RB cord-253746-15w4gquq 6 12 without without IN cord-253746-15w4gquq 6 13 much much JJ cord-253746-15w4gquq 6 14 attention attention NN cord-253746-15w4gquq 6 15 to to IN cord-253746-15w4gquq 6 16 patients patient NNS cord-253746-15w4gquq 6 17 ' ' POS cord-253746-15w4gquq 6 18 voice voice NN cord-253746-15w4gquq 6 19 so so RB cord-253746-15w4gquq 6 20 far far RB cord-253746-15w4gquq 6 21 . . . cord-253746-15w4gquq 7 1 As as IN cord-253746-15w4gquq 7 2 therapeutic therapeutic JJ cord-253746-15w4gquq 7 3 interventions intervention NNS cord-253746-15w4gquq 7 4 in in IN cord-253746-15w4gquq 7 5 the the DT cord-253746-15w4gquq 7 6 early early JJ cord-253746-15w4gquq 7 7 phase phase NN cord-253746-15w4gquq 7 8 of of IN cord-253746-15w4gquq 7 9 the the DT cord-253746-15w4gquq 7 10 disease disease NN cord-253746-15w4gquq 7 11 are be VBP cord-253746-15w4gquq 7 12 attracting attract VBG cord-253746-15w4gquq 7 13 more more JJR cord-253746-15w4gquq 7 14 and and CC cord-253746-15w4gquq 7 15 more more JJR cord-253746-15w4gquq 7 16 interest interest NN cord-253746-15w4gquq 7 17 , , , cord-253746-15w4gquq 7 18 we -PRON- PRP cord-253746-15w4gquq 7 19 argue argue VBP cord-253746-15w4gquq 7 20 that that IN cord-253746-15w4gquq 7 21 now now RB cord-253746-15w4gquq 7 22 is be VBZ cord-253746-15w4gquq 7 23 the the DT cord-253746-15w4gquq 7 24 time time NN cord-253746-15w4gquq 7 25 to to TO cord-253746-15w4gquq 7 26 involve involve VB cord-253746-15w4gquq 7 27 patients patient NNS cord-253746-15w4gquq 7 28 ' ' POS cord-253746-15w4gquq 7 29 organizations organization NNS cord-253746-15w4gquq 7 30 in in IN cord-253746-15w4gquq 7 31 the the DT cord-253746-15w4gquq 7 32 design design NN cord-253746-15w4gquq 7 33 of of IN cord-253746-15w4gquq 7 34 clinical clinical JJ cord-253746-15w4gquq 7 35 protocols protocol NNS cord-253746-15w4gquq 7 36 in in IN cord-253746-15w4gquq 7 37 order order NN cord-253746-15w4gquq 7 38 to to TO cord-253746-15w4gquq 7 39 define define VB cord-253746-15w4gquq 7 40 the the DT cord-253746-15w4gquq 7 41 most most RBS cord-253746-15w4gquq 7 42 relevant relevant JJ cord-253746-15w4gquq 7 43 end end NN cord-253746-15w4gquq 7 44 - - HYPH cord-253746-15w4gquq 7 45 points point NNS cord-253746-15w4gquq 7 46 and and CC cord-253746-15w4gquq 7 47 assess assess VB cord-253746-15w4gquq 7 48 the the DT cord-253746-15w4gquq 7 49 risk risk NN cord-253746-15w4gquq 7 50 - - HYPH cord-253746-15w4gquq 7 51 benefit benefit NN cord-253746-15w4gquq 7 52 balance balance NN cord-253746-15w4gquq 7 53 of of IN cord-253746-15w4gquq 7 54 new new JJ cord-253746-15w4gquq 7 55 therapies therapy NNS cord-253746-15w4gquq 7 56 . . . cord-253746-15w4gquq 8 1 Since since IN cord-253746-15w4gquq 8 2 the the DT cord-253746-15w4gquq 8 3 end end NN cord-253746-15w4gquq 8 4 of of IN cord-253746-15w4gquq 8 5 December December NNP cord-253746-15w4gquq 8 6 2019 2019 CD cord-253746-15w4gquq 8 7 when when WRB cord-253746-15w4gquq 8 8 a a DT cord-253746-15w4gquq 8 9 pneumonia pneumonia NN cord-253746-15w4gquq 8 10 outbreak outbreak NN cord-253746-15w4gquq 8 11 of of IN cord-253746-15w4gquq 8 12 unknown unknown JJ cord-253746-15w4gquq 8 13 origin origin NN cord-253746-15w4gquq 8 14 was be VBD cord-253746-15w4gquq 8 15 reported report VBN cord-253746-15w4gquq 8 16 in in IN cord-253746-15w4gquq 8 17 China China NNP cord-253746-15w4gquq 8 18 , , , cord-253746-15w4gquq 8 19 scientific scientific JJ cord-253746-15w4gquq 8 20 knowledge knowledge NN cord-253746-15w4gquq 8 21 on on IN cord-253746-15w4gquq 8 22 COVID-19 COVID-19 NNP cord-253746-15w4gquq 8 23 progressed progress VBD cord-253746-15w4gquq 8 24 at at IN cord-253746-15w4gquq 8 25 an an DT cord-253746-15w4gquq 8 26 unprecedented unprecedented JJ cord-253746-15w4gquq 8 27 pace pace NN cord-253746-15w4gquq 8 28 . . . cord-253746-15w4gquq 9 1 Within within IN cord-253746-15w4gquq 9 2 a a DT cord-253746-15w4gquq 9 3 few few JJ cord-253746-15w4gquq 9 4 months month NNS cord-253746-15w4gquq 9 5 , , , cord-253746-15w4gquq 9 6 SARS SARS NNP cord-253746-15w4gquq 9 7 - - HYPH cord-253746-15w4gquq 9 8 CoV-2 CoV-2 NNP cord-253746-15w4gquq 9 9 was be VBD cord-253746-15w4gquq 9 10 identified identify VBN cord-253746-15w4gquq 9 11 as as IN cord-253746-15w4gquq 9 12 the the DT cord-253746-15w4gquq 9 13 culprit culprit NN cord-253746-15w4gquq 9 14 agent agent NN cord-253746-15w4gquq 9 15 , , , cord-253746-15w4gquq 9 16 mechanisms mechanism NNS cord-253746-15w4gquq 9 17 by by IN cord-253746-15w4gquq 9 18 which which WDT cord-253746-15w4gquq 9 19 it -PRON- PRP cord-253746-15w4gquq 9 20 infects infect VBZ cord-253746-15w4gquq 9 21 cells cell NNS cord-253746-15w4gquq 9 22 were be VBD cord-253746-15w4gquq 9 23 deciphered decipher VBN cord-253746-15w4gquq 9 24 and and CC cord-253746-15w4gquq 9 25 causes cause NNS cord-253746-15w4gquq 9 26 of of IN cord-253746-15w4gquq 9 27 organ organ NN cord-253746-15w4gquq 9 28 damage damage NN cord-253746-15w4gquq 9 29 were be VBD cord-253746-15w4gquq 9 30 identified identify VBN cord-253746-15w4gquq 9 31 . . . cord-253746-15w4gquq 10 1 This this DT cord-253746-15w4gquq 10 2 has have VBZ cord-253746-15w4gquq 10 3 been be VBN cord-253746-15w4gquq 10 4 possible possible JJ cord-253746-15w4gquq 10 5 because because IN cord-253746-15w4gquq 10 6 scientific scientific JJ cord-253746-15w4gquq 10 7 data datum NNS cord-253746-15w4gquq 10 8 were be VBD cord-253746-15w4gquq 10 9 never never RB cord-253746-15w4gquq 10 10 shared share VBN cord-253746-15w4gquq 10 11 so so RB cord-253746-15w4gquq 10 12 quickly quickly RB cord-253746-15w4gquq 10 13 and and CC cord-253746-15w4gquq 10 14 transparently transparently RB cord-253746-15w4gquq 10 15 , , , cord-253746-15w4gquq 10 16 with with IN cord-253746-15w4gquq 10 17 essential essential JJ cord-253746-15w4gquq 10 18 results result NNS cord-253746-15w4gquq 10 19 being be VBG cord-253746-15w4gquq 10 20 exchanged exchange VBN cord-253746-15w4gquq 10 21 and and CC cord-253746-15w4gquq 10 22 made make VBN cord-253746-15w4gquq 10 23 available available JJ cord-253746-15w4gquq 10 24 in in IN cord-253746-15w4gquq 10 25 real real JJ cord-253746-15w4gquq 10 26 time time NN cord-253746-15w4gquq 10 27 to to IN cord-253746-15w4gquq 10 28 the the DT cord-253746-15w4gquq 10 29 entire entire JJ cord-253746-15w4gquq 10 30 scientific scientific JJ cord-253746-15w4gquq 10 31 community community NN cord-253746-15w4gquq 10 32 . . . cord-253746-15w4gquq 11 1 Now now RB cord-253746-15w4gquq 11 2 that that IN cord-253746-15w4gquq 11 3 we -PRON- PRP cord-253746-15w4gquq 11 4 enter enter VBP cord-253746-15w4gquq 11 5 a a DT cord-253746-15w4gquq 11 6 new new JJ cord-253746-15w4gquq 11 7 phase phase NN cord-253746-15w4gquq 11 8 during during IN cord-253746-15w4gquq 11 9 which which WDT cord-253746-15w4gquq 11 10 science science NN cord-253746-15w4gquq 11 11 must must MD cord-253746-15w4gquq 11 12 be be VB cord-253746-15w4gquq 11 13 translated translate VBN cord-253746-15w4gquq 11 14 in in IN cord-253746-15w4gquq 11 15 innovative innovative JJ cord-253746-15w4gquq 11 16 medicines medicine NNS cord-253746-15w4gquq 11 17 and and CC cord-253746-15w4gquq 11 18 vaccines vaccine NNS cord-253746-15w4gquq 11 19 , , , cord-253746-15w4gquq 11 20 a a DT cord-253746-15w4gquq 11 21 key key JJ cord-253746-15w4gquq 11 22 question question NN cord-253746-15w4gquq 11 23 is be VBZ cord-253746-15w4gquq 11 24 whether whether IN cord-253746-15w4gquq 11 25 collective collective JJ cord-253746-15w4gquq 11 26 intelligence intelligence NN cord-253746-15w4gquq 11 27 will will MD cord-253746-15w4gquq 11 28 remain remain VB cord-253746-15w4gquq 11 29 mobilized mobilize VBN cord-253746-15w4gquq 11 30 in in IN cord-253746-15w4gquq 11 31 a a DT cord-253746-15w4gquq 11 32 similar similar JJ cord-253746-15w4gquq 11 33 manner manner NN cord-253746-15w4gquq 11 34 . . . cord-253746-15w4gquq 12 1 Indeed indeed RB cord-253746-15w4gquq 12 2 , , , cord-253746-15w4gquq 12 3 collaboration collaboration NN cord-253746-15w4gquq 12 4 across across IN cord-253746-15w4gquq 12 5 borders border NNS cord-253746-15w4gquq 12 6 will will MD cord-253746-15w4gquq 12 7 be be VB cord-253746-15w4gquq 12 8 essential essential JJ cord-253746-15w4gquq 12 9 to to TO cord-253746-15w4gquq 12 10 overcome overcome VB cord-253746-15w4gquq 12 11 COVID-19 COVID-19 NNP cord-253746-15w4gquq 12 12 . . . cord-253746-15w4gquq 13 1 Not not RB cord-253746-15w4gquq 13 2 only only RB cord-253746-15w4gquq 13 3 collaboration collaboration NN cord-253746-15w4gquq 13 4 between between IN cord-253746-15w4gquq 13 5 countries country NNS cord-253746-15w4gquq 13 6 , , , cord-253746-15w4gquq 13 7 but but CC cord-253746-15w4gquq 13 8 also also RB cord-253746-15w4gquq 13 9 between between IN cord-253746-15w4gquq 13 10 academia academia NN cord-253746-15w4gquq 13 11 and and CC cord-253746-15w4gquq 13 12 industry industry NN cord-253746-15w4gquq 13 13 , , , cord-253746-15w4gquq 13 14 and and CC cord-253746-15w4gquq 13 15 between between IN cord-253746-15w4gquq 13 16 public public JJ cord-253746-15w4gquq 13 17 and and CC cord-253746-15w4gquq 13 18 private private JJ cord-253746-15w4gquq 13 19 sectors sector NNS cord-253746-15w4gquq 13 20 . . . cord-253746-15w4gquq 14 1 The the DT cord-253746-15w4gquq 14 2 challenge challenge NN cord-253746-15w4gquq 14 3 is be VBZ cord-253746-15w4gquq 14 4 not not RB cord-253746-15w4gquq 14 5 only only RB cord-253746-15w4gquq 14 6 to to TO cord-253746-15w4gquq 14 7 discover discover VB cord-253746-15w4gquq 14 8 the the DT cord-253746-15w4gquq 14 9 right right JJ cord-253746-15w4gquq 14 10 targets target NNS cord-253746-15w4gquq 14 11 for for IN cord-253746-15w4gquq 14 12 anti anti JJ cord-253746-15w4gquq 14 13 - - JJ cord-253746-15w4gquq 14 14 COVID-19 covid-19 JJ cord-253746-15w4gquq 14 15 therapies therapy NNS cord-253746-15w4gquq 14 16 and and CC cord-253746-15w4gquq 14 17 vaccines vaccine NNS cord-253746-15w4gquq 14 18 , , , cord-253746-15w4gquq 14 19 but but CC cord-253746-15w4gquq 14 20 also also RB cord-253746-15w4gquq 14 21 to to TO cord-253746-15w4gquq 14 22 ensure ensure VB cord-253746-15w4gquq 14 23 that that IN cord-253746-15w4gquq 14 24 the the DT cord-253746-15w4gquq 14 25 new new JJ cord-253746-15w4gquq 14 26 products product NNS cord-253746-15w4gquq 14 27 will will MD cord-253746-15w4gquq 14 28 be be VB cord-253746-15w4gquq 14 29 both both DT cord-253746-15w4gquq 14 30 efficient efficient JJ cord-253746-15w4gquq 14 31 and and CC cord-253746-15w4gquq 14 32 safe safe JJ cord-253746-15w4gquq 14 33 , , , cord-253746-15w4gquq 14 34 that that IN cord-253746-15w4gquq 14 35 they -PRON- PRP cord-253746-15w4gquq 14 36 can can MD cord-253746-15w4gquq 14 37 be be VB cord-253746-15w4gquq 14 38 manufactured manufacture VBN cord-253746-15w4gquq 14 39 at at IN cord-253746-15w4gquq 14 40 full full JJ cord-253746-15w4gquq 14 41 industrial industrial JJ cord-253746-15w4gquq 14 42 scale scale NN cord-253746-15w4gquq 14 43 , , , cord-253746-15w4gquq 14 44 and and CC cord-253746-15w4gquq 14 45 that that IN cord-253746-15w4gquq 14 46 they -PRON- PRP cord-253746-15w4gquq 14 47 will will MD cord-253746-15w4gquq 14 48 be be VB cord-253746-15w4gquq 14 49 accessible accessible JJ cord-253746-15w4gquq 14 50 worldwide worldwide RB cord-253746-15w4gquq 14 51 at at IN cord-253746-15w4gquq 14 52 affordable affordable JJ cord-253746-15w4gquq 14 53 prices price NNS cord-253746-15w4gquq 14 54 . . . cord-253746-15w4gquq 15 1 Several several JJ cord-253746-15w4gquq 15 2 initiatives initiative NNS cord-253746-15w4gquq 15 3 have have VBP cord-253746-15w4gquq 15 4 been be VBN cord-253746-15w4gquq 15 5 launched launch VBN cord-253746-15w4gquq 15 6 to to TO cord-253746-15w4gquq 15 7 meet meet VB cord-253746-15w4gquq 15 8 this this DT cord-253746-15w4gquq 15 9 challenge challenge NN cord-253746-15w4gquq 15 10 and and CC cord-253746-15w4gquq 15 11 provide provide VB cord-253746-15w4gquq 15 12 incentives incentive NNS cord-253746-15w4gquq 15 13 to to TO cord-253746-15w4gquq 15 14 foster foster VB cord-253746-15w4gquq 15 15 collaborative collaborative JJ cord-253746-15w4gquq 15 16 endeavors endeavor NNS cord-253746-15w4gquq 15 17 . . . cord-253746-15w4gquq 16 1 Both both DT cord-253746-15w4gquq 16 2 the the DT cord-253746-15w4gquq 16 3 " " `` cord-253746-15w4gquq 16 4 Accelerating accelerate VBG cord-253746-15w4gquq 16 5 COVID-19 COVID-19 NNP cord-253746-15w4gquq 16 6 Therapeutic Therapeutic NNP cord-253746-15w4gquq 16 7 Interventions Interventions NNPS cord-253746-15w4gquq 16 8 and and CC cord-253746-15w4gquq 16 9 Vaccines Vaccines NNPS cord-253746-15w4gquq 16 10 " " '' cord-253746-15w4gquq 16 11 ( ( -LRB- cord-253746-15w4gquq 16 12 ACTIV ACTIV NNP cord-253746-15w4gquq 16 13 ) ) -RRB- cord-253746-15w4gquq 16 14 initiative initiative NN cord-253746-15w4gquq 16 15 in in IN cord-253746-15w4gquq 16 16 the the DT cord-253746-15w4gquq 16 17 USA USA NNP cord-253746-15w4gquq 16 18 ( ( -LRB- cord-253746-15w4gquq 16 19 1 1 CD cord-253746-15w4gquq 16 20 ) ) -RRB- cord-253746-15w4gquq 16 21 and and CC cord-253746-15w4gquq 16 22 the the DT cord-253746-15w4gquq 16 23 " " `` cord-253746-15w4gquq 16 24 Coronavirus Coronavirus NNP cord-253746-15w4gquq 16 25 Global Global NNP cord-253746-15w4gquq 16 26 Response Response NNP cord-253746-15w4gquq 16 27 " " '' cord-253746-15w4gquq 16 28 launched launch VBN cord-253746-15w4gquq 16 29 by by IN cord-253746-15w4gquq 16 30 the the DT cord-253746-15w4gquq 16 31 European European NNP cord-253746-15w4gquq 16 32 Commission Commission NNP cord-253746-15w4gquq 16 33 ( ( -LRB- cord-253746-15w4gquq 16 34 https://global-response.europa.eu/index_en https://global-response.europa.eu/index_en NFP cord-253746-15w4gquq 16 35 ) ) -RRB- cord-253746-15w4gquq 16 36 will will MD cord-253746-15w4gquq 16 37 support support VB cord-253746-15w4gquq 16 38 publicprivate publicprivate NN cord-253746-15w4gquq 16 39 partnerships partnership NNS cord-253746-15w4gquq 16 40 and and CC cord-253746-15w4gquq 16 41 multi multi JJ cord-253746-15w4gquq 16 42 - - JJ cord-253746-15w4gquq 16 43 stakeholder stakeholder NN cord-253746-15w4gquq 16 44 consortia consortium NNS cord-253746-15w4gquq 16 45 . . . cord-253746-15w4gquq 17 1 In in IN cord-253746-15w4gquq 17 2 this this DT cord-253746-15w4gquq 17 3 editorial editorial JJ cord-253746-15w4gquq 17 4 perspective perspective NN cord-253746-15w4gquq 17 5 , , , cord-253746-15w4gquq 17 6 we -PRON- PRP cord-253746-15w4gquq 17 7 argue argue VBP cord-253746-15w4gquq 17 8 that that IN cord-253746-15w4gquq 17 9 patients patient NNS cord-253746-15w4gquq 17 10 ' ' POS cord-253746-15w4gquq 17 11 voice voice NN cord-253746-15w4gquq 17 12 will will MD cord-253746-15w4gquq 17 13 be be VB cord-253746-15w4gquq 17 14 essential essential JJ cord-253746-15w4gquq 17 15 to to TO cord-253746-15w4gquq 17 16 ensure ensure VB cord-253746-15w4gquq 17 17 uptake uptake NN cord-253746-15w4gquq 17 18 in in IN cord-253746-15w4gquq 17 19 the the DT cord-253746-15w4gquq 17 20 wider wide JJR cord-253746-15w4gquq 17 21 public public NN cord-253746-15w4gquq 17 22 of of IN cord-253746-15w4gquq 17 23 new new JJ cord-253746-15w4gquq 17 24 therapies therapy NNS cord-253746-15w4gquq 17 25 and and CC cord-253746-15w4gquq 17 26 vaccines vaccine NNS cord-253746-15w4gquq 17 27 resulting result VBG cord-253746-15w4gquq 17 28 from from IN cord-253746-15w4gquq 17 29 these these DT cord-253746-15w4gquq 17 30 initiatives initiative NNS cord-253746-15w4gquq 17 31 . . . cord-253746-15w4gquq 18 1 During during IN cord-253746-15w4gquq 18 2 the the DT cord-253746-15w4gquq 18 3 exploding explode VBG cord-253746-15w4gquq 18 4 phase phase NN cord-253746-15w4gquq 18 5 of of IN cord-253746-15w4gquq 18 6 the the DT cord-253746-15w4gquq 18 7 pandemic pandemic NN cord-253746-15w4gquq 18 8 , , , cord-253746-15w4gquq 18 9 the the DT cord-253746-15w4gquq 18 10 immediate immediate JJ cord-253746-15w4gquq 18 11 priority priority NN cord-253746-15w4gquq 18 12 was be VBD cord-253746-15w4gquq 18 13 to to TO cord-253746-15w4gquq 18 14 identify identify VB cord-253746-15w4gquq 18 15 compounds compound NNS cord-253746-15w4gquq 18 16 able able JJ cord-253746-15w4gquq 18 17 to to TO cord-253746-15w4gquq 18 18 mitigate mitigate VB cord-253746-15w4gquq 18 19 the the DT cord-253746-15w4gquq 18 20 most most RBS cord-253746-15w4gquq 18 21 severe severe JJ cord-253746-15w4gquq 18 22 cases case NNS cord-253746-15w4gquq 18 23 of of IN cord-253746-15w4gquq 18 24 COVID-19 covid-19 NN cord-253746-15w4gquq 18 25 . . . cord-253746-15w4gquq 19 1 Indeed indeed RB cord-253746-15w4gquq 19 2 , , , cord-253746-15w4gquq 19 3 doctors doctor NNS cord-253746-15w4gquq 19 4 facing face VBG cord-253746-15w4gquq 19 5 patients patient NNS cord-253746-15w4gquq 19 6 dying die VBG cord-253746-15w4gquq 19 7 of of IN cord-253746-15w4gquq 19 8 fulminant fulminant JJ cord-253746-15w4gquq 19 9 pneumonia pneumonia NN cord-253746-15w4gquq 19 10 desperately desperately RB cord-253746-15w4gquq 19 11 look look VBP cord-253746-15w4gquq 19 12 for for IN cord-253746-15w4gquq 19 13 potential potential JJ cord-253746-15w4gquq 19 14 therapies therapy NNS cord-253746-15w4gquq 19 15 that that WDT cord-253746-15w4gquq 19 16 can can MD cord-253746-15w4gquq 19 17 be be VB cord-253746-15w4gquq 19 18 immediately immediately RB cord-253746-15w4gquq 19 19 available available JJ cord-253746-15w4gquq 19 20 . . . cord-253746-15w4gquq 20 1 Unfortunately unfortunately RB cord-253746-15w4gquq 20 2 , , , cord-253746-15w4gquq 20 3 the the DT cord-253746-15w4gquq 20 4 overall overall JJ cord-253746-15w4gquq 20 5 outcome outcome NN cord-253746-15w4gquq 20 6 of of IN cord-253746-15w4gquq 20 7 the the DT cord-253746-15w4gquq 20 8 clinical clinical JJ cord-253746-15w4gquq 20 9 trials trial NNS cord-253746-15w4gquq 20 10 conducted conduct VBN cord-253746-15w4gquq 20 11 during during IN cord-253746-15w4gquq 20 12 the the DT cord-253746-15w4gquq 20 13 initial initial JJ cord-253746-15w4gquq 20 14 phase phase NN cord-253746-15w4gquq 20 15 of of IN cord-253746-15w4gquq 20 16 the the DT cord-253746-15w4gquq 20 17 pandemic pandemic NN cord-253746-15w4gquq 20 18 was be VBD cord-253746-15w4gquq 20 19 by by IN cord-253746-15w4gquq 20 20 and and CC cord-253746-15w4gquq 20 21 large large JJ cord-253746-15w4gquq 20 22 disappointing disappointing JJ cord-253746-15w4gquq 20 23 . . . cord-253746-15w4gquq 21 1 A a DT cord-253746-15w4gquq 21 2 huge huge JJ cord-253746-15w4gquq 21 3 number number NN cord-253746-15w4gquq 21 4 of of IN cord-253746-15w4gquq 21 5 small small JJ cord-253746-15w4gquq 21 6 statistically statistically RB cord-253746-15w4gquq 21 7 underpowered underpowered JJ cord-253746-15w4gquq 21 8 trials trial NNS cord-253746-15w4gquq 21 9 were be VBD cord-253746-15w4gquq 21 10 simultaneously simultaneously RB cord-253746-15w4gquq 21 11 launched launch VBN cord-253746-15w4gquq 21 12 ( ( -LRB- cord-253746-15w4gquq 21 13 2 2 CD cord-253746-15w4gquq 21 14 ) ) -RRB- cord-253746-15w4gquq 21 15 and and CC cord-253746-15w4gquq 21 16 a a DT cord-253746-15w4gquq 21 17 recent recent JJ cord-253746-15w4gquq 21 18 paper paper NN cord-253746-15w4gquq 21 19 reported report VBD cord-253746-15w4gquq 21 20 that that IN cord-253746-15w4gquq 21 21 only only RB cord-253746-15w4gquq 21 22 30 30 CD cord-253746-15w4gquq 21 23 out out IN cord-253746-15w4gquq 21 24 of of IN cord-253746-15w4gquq 21 25 1,840 1,840 CD cord-253746-15w4gquq 21 26 registered register VBN cord-253746-15w4gquq 21 27 trials trial NNS cord-253746-15w4gquq 21 28 have have VBP cord-253746-15w4gquq 21 29 actually actually RB cord-253746-15w4gquq 21 30 been be VBN cord-253746-15w4gquq 21 31 reported report VBN cord-253746-15w4gquq 21 32 , , , cord-253746-15w4gquq 21 33 and and CC cord-253746-15w4gquq 21 34 very very RB cord-253746-15w4gquq 21 35 few few JJ cord-253746-15w4gquq 21 36 trials trial NNS cord-253746-15w4gquq 21 37 addressed address VBD cord-253746-15w4gquq 21 38 early early JJ cord-253746-15w4gquq 21 39 interventions intervention NNS cord-253746-15w4gquq 21 40 aiming aim VBG cord-253746-15w4gquq 21 41 at at IN cord-253746-15w4gquq 21 42 preventing prevent VBG cord-253746-15w4gquq 21 43 hospitalization hospitalization NN cord-253746-15w4gquq 21 44 ( ( -LRB- cord-253746-15w4gquq 21 45 3 3 CD cord-253746-15w4gquq 21 46 ) ) -RRB- cord-253746-15w4gquq 21 47 . . . cord-253746-15w4gquq 22 1 The the DT cord-253746-15w4gquq 22 2 most most RBS cord-253746-15w4gquq 22 3 pertinent pertinent JJ cord-253746-15w4gquq 22 4 trials trial NNS cord-253746-15w4gquq 22 5 were be VBD cord-253746-15w4gquq 22 6 the the DT cord-253746-15w4gquq 22 7 so so RB cord-253746-15w4gquq 22 8 - - HYPH cord-253746-15w4gquq 22 9 called call VBN cord-253746-15w4gquq 22 10 adaptive adaptive JJ cord-253746-15w4gquq 22 11 trials trial NNS cord-253746-15w4gquq 22 12 which which WDT cord-253746-15w4gquq 22 13 conciliate conciliate VBP cord-253746-15w4gquq 22 14 the the DT cord-253746-15w4gquq 22 15 scientific scientific JJ cord-253746-15w4gquq 22 16 rigor rigor NN cord-253746-15w4gquq 22 17 brought bring VBN cord-253746-15w4gquq 22 18 by by IN cord-253746-15w4gquq 22 19 randomization randomization NN cord-253746-15w4gquq 22 20 and and CC cord-253746-15w4gquq 22 21 the the DT cord-253746-15w4gquq 22 22 ethical ethical JJ cord-253746-15w4gquq 22 23 duty duty NN cord-253746-15w4gquq 22 24 to to TO cord-253746-15w4gquq 22 25 provide provide VB cord-253746-15w4gquq 22 26 patients patient NNS cord-253746-15w4gquq 22 27 with with IN cord-253746-15w4gquq 22 28 a a DT cord-253746-15w4gquq 22 29 potentially potentially RB cord-253746-15w4gquq 22 30 beneficial beneficial JJ cord-253746-15w4gquq 22 31 therapy therapy NN cord-253746-15w4gquq 22 32 . . . cord-253746-15w4gquq 23 1 Indeed indeed RB cord-253746-15w4gquq 23 2 , , , cord-253746-15w4gquq 23 3 adaptive adaptive JJ cord-253746-15w4gquq 23 4 trial trial NN cord-253746-15w4gquq 23 5 designs design NNS cord-253746-15w4gquq 23 6 allow allow VBP cord-253746-15w4gquq 23 7 to to TO cord-253746-15w4gquq 23 8 change change VB cord-253746-15w4gquq 23 9 therapeutic therapeutic JJ cord-253746-15w4gquq 23 10 options option NNS cord-253746-15w4gquq 23 11 in in IN cord-253746-15w4gquq 23 12 the the DT cord-253746-15w4gquq 23 13 course course NN cord-253746-15w4gquq 23 14 of of IN cord-253746-15w4gquq 23 15 a a DT cord-253746-15w4gquq 23 16 study study NN cord-253746-15w4gquq 23 17 according accord VBG cord-253746-15w4gquq 23 18 to to IN cord-253746-15w4gquq 23 19 interim interim JJ cord-253746-15w4gquq 23 20 evaluations evaluation NNS cord-253746-15w4gquq 23 21 and and CC cord-253746-15w4gquq 23 22 inefficient inefficient JJ cord-253746-15w4gquq 23 23 treatments treatment NNS cord-253746-15w4gquq 23 24 can can MD cord-253746-15w4gquq 23 25 be be VB cord-253746-15w4gquq 23 26 withdrawn withdraw VBN cord-253746-15w4gquq 23 27 whereas whereas IN cord-253746-15w4gquq 23 28 newly newly RB cord-253746-15w4gquq 23 29 emerging emerge VBG cord-253746-15w4gquq 23 30 therapies therapy NNS cord-253746-15w4gquq 23 31 can can MD cord-253746-15w4gquq 23 32 be be VB cord-253746-15w4gquq 23 33 introduced introduce VBN cord-253746-15w4gquq 23 34 in in IN cord-253746-15w4gquq 23 35 the the DT cord-253746-15w4gquq 23 36 trial trial NN cord-253746-15w4gquq 23 37 ( ( -LRB- cord-253746-15w4gquq 23 38 4 4 CD cord-253746-15w4gquq 23 39 ) ) -RRB- cord-253746-15w4gquq 23 40 . . . cord-253746-15w4gquq 24 1 Three three CD cord-253746-15w4gquq 24 2 large large JJ cord-253746-15w4gquq 24 3 trials trial NNS cord-253746-15w4gquq 24 4 using use VBG cord-253746-15w4gquq 24 5 such such PDT cord-253746-15w4gquq 24 6 an an DT cord-253746-15w4gquq 24 7 adaptive adaptive JJ cord-253746-15w4gquq 24 8 design design NN cord-253746-15w4gquq 24 9 were be VBD cord-253746-15w4gquq 24 10 launched launch VBN cord-253746-15w4gquq 24 11 , , , cord-253746-15w4gquq 24 12 Solidarity Solidarity NNP cord-253746-15w4gquq 24 13 led lead VBD cord-253746-15w4gquq 24 14 by by IN cord-253746-15w4gquq 24 15 the the DT cord-253746-15w4gquq 24 16 World World NNP cord-253746-15w4gquq 24 17 Health Health NNP cord-253746-15w4gquq 24 18 organization organization NN cord-253746-15w4gquq 24 19 ( ( -LRB- cord-253746-15w4gquq 24 20 WHO who WP cord-253746-15w4gquq 24 21 ) ) -RRB- cord-253746-15w4gquq 24 22 , , , cord-253746-15w4gquq 24 23 Discovery Discovery NNP cord-253746-15w4gquq 24 24 by by IN cord-253746-15w4gquq 24 25 the the DT cord-253746-15w4gquq 24 26 French French NNP cord-253746-15w4gquq 24 27 Institute Institute NNP cord-253746-15w4gquq 24 28 for for IN cord-253746-15w4gquq 24 29 Health Health NNP cord-253746-15w4gquq 24 30 and and CC cord-253746-15w4gquq 24 31 Medical Medical NNP cord-253746-15w4gquq 24 32 Research Research NNP cord-253746-15w4gquq 24 33 ( ( -LRB- cord-253746-15w4gquq 24 34 INSERM INSERM NNP cord-253746-15w4gquq 24 35 ) ) -RRB- cord-253746-15w4gquq 24 36 , , , cord-253746-15w4gquq 24 37 and and CC cord-253746-15w4gquq 24 38 Recovery Recovery NNP cord-253746-15w4gquq 24 39 by by IN cord-253746-15w4gquq 24 40 the the DT cord-253746-15w4gquq 24 41 University University NNP cord-253746-15w4gquq 24 42 of of IN cord-253746-15w4gquq 24 43 Oxford Oxford NNP cord-253746-15w4gquq 24 44 . . . cord-253746-15w4gquq 25 1 Unfortunately unfortunately RB cord-253746-15w4gquq 25 2 , , , cord-253746-15w4gquq 25 3 the the DT cord-253746-15w4gquq 25 4 implementation implementation NN cord-253746-15w4gquq 25 5 of of IN cord-253746-15w4gquq 25 6 Solidarity Solidarity NNP cord-253746-15w4gquq 25 7 and and CC cord-253746-15w4gquq 25 8 Discovery Discovery NNP cord-253746-15w4gquq 25 9 were be VBD cord-253746-15w4gquq 25 10 hampered hamper VBN cord-253746-15w4gquq 25 11 by by IN cord-253746-15w4gquq 25 12 regulatory regulatory JJ cord-253746-15w4gquq 25 13 and and CC cord-253746-15w4gquq 25 14 administrative administrative JJ cord-253746-15w4gquq 25 15 hurdles hurdle NNS cord-253746-15w4gquq 25 16 . . . cord-253746-15w4gquq 26 1 On on IN cord-253746-15w4gquq 26 2 the the DT cord-253746-15w4gquq 26 3 other other JJ cord-253746-15w4gquq 26 4 hand hand NN cord-253746-15w4gquq 26 5 , , , cord-253746-15w4gquq 26 6 Recovery Recovery NNP cord-253746-15w4gquq 26 7 provided provide VBD cord-253746-15w4gquq 26 8 an an DT cord-253746-15w4gquq 26 9 essential essential JJ cord-253746-15w4gquq 26 10 information information NN cord-253746-15w4gquq 26 11 for for IN cord-253746-15w4gquq 26 12 the the DT cord-253746-15w4gquq 26 13 management management NN cord-253746-15w4gquq 26 14 of of IN cord-253746-15w4gquq 26 15 future future JJ cord-253746-15w4gquq 26 16 cases case NNS cord-253746-15w4gquq 26 17 by by IN cord-253746-15w4gquq 26 18 demonstrating demonstrate VBG cord-253746-15w4gquq 26 19 the the DT cord-253746-15w4gquq 26 20 beneficial beneficial JJ cord-253746-15w4gquq 26 21 action action NN cord-253746-15w4gquq 26 22 of of IN cord-253746-15w4gquq 26 23 dexamethasone dexamethasone NN cord-253746-15w4gquq 26 24 in in IN cord-253746-15w4gquq 26 25 reducing reduce VBG cord-253746-15w4gquq 26 26 the the DT cord-253746-15w4gquq 26 27 mortality mortality NN cord-253746-15w4gquq 26 28 of of IN cord-253746-15w4gquq 26 29 patients patient NNS cord-253746-15w4gquq 26 30 with with IN cord-253746-15w4gquq 26 31 the the DT cord-253746-15w4gquq 26 32 most most RBS cord-253746-15w4gquq 26 33 severe severe JJ cord-253746-15w4gquq 26 34 forms form NNS cord-253746-15w4gquq 26 35 of of IN cord-253746-15w4gquq 26 36 the the DT cord-253746-15w4gquq 26 37 disease disease NN cord-253746-15w4gquq 26 38 ( ( -LRB- cord-253746-15w4gquq 26 39 5 5 CD cord-253746-15w4gquq 26 40 ) ) -RRB- cord-253746-15w4gquq 26 41 . . . cord-253746-15w4gquq 27 1 Remdesivir Remdesivir NNP cord-253746-15w4gquq 27 2 is be VBZ cord-253746-15w4gquq 27 3 the the DT cord-253746-15w4gquq 27 4 other other JJ cord-253746-15w4gquq 27 5 treatment treatment NN cord-253746-15w4gquq 27 6 which which WDT cord-253746-15w4gquq 27 7 has have VBZ cord-253746-15w4gquq 27 8 been be VBN cord-253746-15w4gquq 27 9 scientifically scientifically RB cord-253746-15w4gquq 27 10 validated validate VBN cord-253746-15w4gquq 27 11 in in IN cord-253746-15w4gquq 27 12 a a DT cord-253746-15w4gquq 27 13 randomized randomized JJ cord-253746-15w4gquq 27 14 study study NN cord-253746-15w4gquq 27 15 , , , cord-253746-15w4gquq 27 16 again again RB cord-253746-15w4gquq 27 17 in in IN cord-253746-15w4gquq 27 18 hospitalized hospitalize VBN cord-253746-15w4gquq 27 19 patients patient NNS cord-253746-15w4gquq 27 20 with with IN cord-253746-15w4gquq 27 21 serious serious JJ cord-253746-15w4gquq 27 22 illness illness NN cord-253746-15w4gquq 27 23 ( ( -LRB- cord-253746-15w4gquq 27 24 6 6 CD cord-253746-15w4gquq 27 25 ) ) -RRB- cord-253746-15w4gquq 27 26 . . . cord-253746-15w4gquq 28 1 While while IN cord-253746-15w4gquq 28 2 a a DT cord-253746-15w4gquq 28 3 number number NN cord-253746-15w4gquq 28 4 of of IN cord-253746-15w4gquq 28 5 countries country NNS cord-253746-15w4gquq 28 6 are be VBP cord-253746-15w4gquq 28 7 still still RB cord-253746-15w4gquq 28 8 in in IN cord-253746-15w4gquq 28 9 the the DT cord-253746-15w4gquq 28 10 ascending ascending JJ cord-253746-15w4gquq 28 11 limb limb NN cord-253746-15w4gquq 28 12 of of IN cord-253746-15w4gquq 28 13 the the DT cord-253746-15w4gquq 28 14 pandemic pandemic NN cord-253746-15w4gquq 28 15 and and CC cord-253746-15w4gquq 28 16 several several JJ cord-253746-15w4gquq 28 17 others other NNS cord-253746-15w4gquq 28 18 face face VBP cord-253746-15w4gquq 28 19 resurgence resurgence NN cord-253746-15w4gquq 28 20 of of IN cord-253746-15w4gquq 28 21 new new JJ cord-253746-15w4gquq 28 22 cases case NNS cord-253746-15w4gquq 28 23 , , , cord-253746-15w4gquq 28 24 now now RB cord-253746-15w4gquq 28 25 is be VBZ cord-253746-15w4gquq 28 26 the the DT cord-253746-15w4gquq 28 27 time time NN cord-253746-15w4gquq 28 28 to to TO cord-253746-15w4gquq 28 29 reflect reflect VB cord-253746-15w4gquq 28 30 on on IN cord-253746-15w4gquq 28 31 how how WRB cord-253746-15w4gquq 28 32 to to TO cord-253746-15w4gquq 28 33 make make VB cord-253746-15w4gquq 28 34 the the DT cord-253746-15w4gquq 28 35 search search NN cord-253746-15w4gquq 28 36 for for IN cord-253746-15w4gquq 28 37 new new JJ cord-253746-15w4gquq 28 38 COVID-19 COVID-19 NNP cord-253746-15w4gquq 28 39 therapies therapy NNS cord-253746-15w4gquq 28 40 more more RBR cord-253746-15w4gquq 28 41 efficient efficient JJ cord-253746-15w4gquq 28 42 ( ( -LRB- cord-253746-15w4gquq 28 43 7 7 CD cord-253746-15w4gquq 28 44 ) ) -RRB- cord-253746-15w4gquq 28 45 . . . cord-253746-15w4gquq 29 1 Fore Fore NNS cord-253746-15w4gquq 29 2 and and CC cord-253746-15w4gquq 29 3 foremost foremost RB cord-253746-15w4gquq 29 4 , , , cord-253746-15w4gquq 29 5 radical radical JJ cord-253746-15w4gquq 29 6 changes change NNS cord-253746-15w4gquq 29 7 are be VBP cord-253746-15w4gquq 29 8 necessary necessary JJ cord-253746-15w4gquq 29 9 to to TO cord-253746-15w4gquq 29 10 prevent prevent VB cord-253746-15w4gquq 29 11 a a DT cord-253746-15w4gquq 29 12 detrimental detrimental JJ cord-253746-15w4gquq 29 13 competition competition NN cord-253746-15w4gquq 29 14 between between IN cord-253746-15w4gquq 29 15 trials trial NNS cord-253746-15w4gquq 29 16 that that WDT cord-253746-15w4gquq 29 17 are be VBP cord-253746-15w4gquq 29 18 either either CC cord-253746-15w4gquq 29 19 underpowered underpowered JJ cord-253746-15w4gquq 29 20 or or CC cord-253746-15w4gquq 29 21 unrealistic unrealistic JJ cord-253746-15w4gquq 29 22 in in IN cord-253746-15w4gquq 29 23 terms term NNS cord-253746-15w4gquq 29 24 of of IN cord-253746-15w4gquq 29 25 patient patient JJ cord-253746-15w4gquq 29 26 accrual accrual NN cord-253746-15w4gquq 29 27 . . . cord-253746-15w4gquq 30 1 This this DT cord-253746-15w4gquq 30 2 is be VBZ cord-253746-15w4gquq 30 3 an an DT cord-253746-15w4gquq 30 4 ethical ethical JJ cord-253746-15w4gquq 30 5 duty duty NN cord-253746-15w4gquq 30 6 toward toward IN cord-253746-15w4gquq 30 7 patients patient NNS cord-253746-15w4gquq 30 8 which which WDT cord-253746-15w4gquq 30 9 agree agree VBP cord-253746-15w4gquq 30 10 to to TO cord-253746-15w4gquq 30 11 be be VB cord-253746-15w4gquq 30 12 exposed expose VBN cord-253746-15w4gquq 30 13 to to IN cord-253746-15w4gquq 30 14 potential potential JJ cord-253746-15w4gquq 30 15 risks risk NNS cord-253746-15w4gquq 30 16 with with IN cord-253746-15w4gquq 30 17 the the DT cord-253746-15w4gquq 30 18 understanding understanding NN cord-253746-15w4gquq 30 19 that that IN cord-253746-15w4gquq 30 20 by by IN cord-253746-15w4gquq 30 21 doing do VBG cord-253746-15w4gquq 30 22 so so RB cord-253746-15w4gquq 30 23 they -PRON- PRP cord-253746-15w4gquq 30 24 contribute contribute VBP cord-253746-15w4gquq 30 25 to to TO cord-253746-15w4gquq 30 26 create create VB cord-253746-15w4gquq 30 27 firm firm JJ cord-253746-15w4gquq 30 28 evidence evidence NN cord-253746-15w4gquq 30 29 regarding regard VBG cord-253746-15w4gquq 30 30 efficacy efficacy NN cord-253746-15w4gquq 30 31 and and CC cord-253746-15w4gquq 30 32 safety safety NN cord-253746-15w4gquq 30 33 of of IN cord-253746-15w4gquq 30 34 the the DT cord-253746-15w4gquq 30 35 new new JJ cord-253746-15w4gquq 30 36 medicines medicine NNS cord-253746-15w4gquq 30 37 they -PRON- PRP cord-253746-15w4gquq 30 38 receive receive VBP cord-253746-15w4gquq 30 39 . . . cord-253746-15w4gquq 31 1 Therefore therefore RB cord-253746-15w4gquq 31 2 , , , cord-253746-15w4gquq 31 3 it -PRON- PRP cord-253746-15w4gquq 31 4 is be VBZ cord-253746-15w4gquq 31 5 essential essential JJ cord-253746-15w4gquq 31 6 that that IN cord-253746-15w4gquq 31 7 trials trial NNS cord-253746-15w4gquq 31 8 are be VBP cord-253746-15w4gquq 31 9 designed design VBN cord-253746-15w4gquq 31 10 to to TO cord-253746-15w4gquq 31 11 include include VB cord-253746-15w4gquq 31 12 sufficient sufficient JJ cord-253746-15w4gquq 31 13 numbers number NNS cord-253746-15w4gquq 31 14 of of IN cord-253746-15w4gquq 31 15 patients patient NNS cord-253746-15w4gquq 31 16 within within IN cord-253746-15w4gquq 31 17 the the DT cord-253746-15w4gquq 31 18 period period NN cord-253746-15w4gquq 31 19 of of IN cord-253746-15w4gquq 31 20 time time NN cord-253746-15w4gquq 31 21 during during IN cord-253746-15w4gquq 31 22 which which WDT cord-253746-15w4gquq 31 23 the the DT cord-253746-15w4gquq 31 24 pandemic pandemic NN cord-253746-15w4gquq 31 25 is be VBZ cord-253746-15w4gquq 31 26 expected expect VBN cord-253746-15w4gquq 31 27 to to TO cord-253746-15w4gquq 31 28 be be VB cord-253746-15w4gquq 31 29 active active JJ cord-253746-15w4gquq 31 30 . . . cord-253746-15w4gquq 32 1 The the DT cord-253746-15w4gquq 32 2 insufficient insufficient JJ cord-253746-15w4gquq 32 3 pace pace NN cord-253746-15w4gquq 32 4 of of IN cord-253746-15w4gquq 32 5 patient patient JJ cord-253746-15w4gquq 32 6 enrollment enrollment NN cord-253746-15w4gquq 32 7 is be VBZ cord-253746-15w4gquq 32 8 indeed indeed RB cord-253746-15w4gquq 32 9 the the DT cord-253746-15w4gquq 32 10 most most RBS cord-253746-15w4gquq 32 11 frequent frequent JJ cord-253746-15w4gquq 32 12 cause cause NN cord-253746-15w4gquq 32 13 of of IN cord-253746-15w4gquq 32 14 trial trial NN cord-253746-15w4gquq 32 15 failure failure NN cord-253746-15w4gquq 32 16 . . . cord-253746-15w4gquq 33 1 This this DT cord-253746-15w4gquq 33 2 has have VBZ cord-253746-15w4gquq 33 3 been be VBN cord-253746-15w4gquq 33 4 a a DT cord-253746-15w4gquq 33 5 matter matter NN cord-253746-15w4gquq 33 6 of of IN cord-253746-15w4gquq 33 7 great great JJ cord-253746-15w4gquq 33 8 concern concern NN cord-253746-15w4gquq 33 9 during during IN cord-253746-15w4gquq 33 10 the the DT cord-253746-15w4gquq 33 11 recent recent JJ cord-253746-15w4gquq 33 12 Ebola Ebola NNP cord-253746-15w4gquq 33 13 virus virus NN cord-253746-15w4gquq 33 14 and and CC cord-253746-15w4gquq 33 15 Zika Zika NNP cord-253746-15w4gquq 33 16 virus virus NN cord-253746-15w4gquq 33 17 outbreak outbreak NN cord-253746-15w4gquq 33 18 ( ( -LRB- cord-253746-15w4gquq 33 19 8) 8) NN cord-253746-15w4gquq 33 20 . . . cord-253746-15w4gquq 34 1 More More JJR cord-253746-15w4gquq 34 2 than than IN cord-253746-15w4gquq 34 3 ever ever RB cord-253746-15w4gquq 34 4 , , , cord-253746-15w4gquq 34 5 there there EX cord-253746-15w4gquq 34 6 is be VBZ cord-253746-15w4gquq 34 7 a a DT cord-253746-15w4gquq 34 8 huge huge JJ cord-253746-15w4gquq 34 9 need need NN cord-253746-15w4gquq 34 10 for for IN cord-253746-15w4gquq 34 11 better well JJR cord-253746-15w4gquq 34 12 coordination coordination NN cord-253746-15w4gquq 34 13 and and CC cord-253746-15w4gquq 34 14 management management NN cord-253746-15w4gquq 34 15 of of IN cord-253746-15w4gquq 34 16 trials trial NNS cord-253746-15w4gquq 34 17 through through IN cord-253746-15w4gquq 34 18 the the DT cord-253746-15w4gquq 34 19 establishment establishment NN cord-253746-15w4gquq 34 20 of of IN cord-253746-15w4gquq 34 21 collaborative collaborative JJ cord-253746-15w4gquq 34 22 infrastructures infrastructure NNS cord-253746-15w4gquq 34 23 and and CC cord-253746-15w4gquq 34 24 platforms platform NNS cord-253746-15w4gquq 34 25 . . . cord-253746-15w4gquq 35 1 In in IN cord-253746-15w4gquq 35 2 this this DT cord-253746-15w4gquq 35 3 regard regard NN cord-253746-15w4gquq 35 4 , , , cord-253746-15w4gquq 35 5 besides besides IN cord-253746-15w4gquq 35 6 the the DT cord-253746-15w4gquq 35 7 ACTIV ACTIV NNP cord-253746-15w4gquq 35 8 program program NN cord-253746-15w4gquq 35 9 in in IN cord-253746-15w4gquq 35 10 the the DT cord-253746-15w4gquq 35 11 US US NNP cord-253746-15w4gquq 35 12 ( ( -LRB- cord-253746-15w4gquq 35 13 https://bit.ly/32Ct8Fz https://bit.ly/32ct8fz NN cord-253746-15w4gquq 35 14 ) ) -RRB- cord-253746-15w4gquq 35 15 , , , cord-253746-15w4gquq 35 16 the the DT cord-253746-15w4gquq 35 17 Accelerating Accelerating NNP cord-253746-15w4gquq 35 18 COVID-19 COVID-19 NNP cord-253746-15w4gquq 35 19 Research Research NNP cord-253746-15w4gquq 35 20 and and CC cord-253746-15w4gquq 35 21 Development Development NNP cord-253746-15w4gquq 35 22 platform platform NN cord-253746-15w4gquq 35 23 ( ( -LRB- cord-253746-15w4gquq 35 24 ACCORD ACCORD NNP cord-253746-15w4gquq 35 25 ) ) -RRB- cord-253746-15w4gquq 35 26 in in IN cord-253746-15w4gquq 35 27 the the DT cord-253746-15w4gquq 35 28 UK UK NNP cord-253746-15w4gquq 35 29 ( ( -LRB- cord-253746-15w4gquq 35 30 https://bit.ly/30vzhRj https://bit.ly/30vzhrj UH cord-253746-15w4gquq 35 31 ) ) -RRB- cord-253746-15w4gquq 35 32 and and CC cord-253746-15w4gquq 35 33 the the DT cord-253746-15w4gquq 35 34 ERAvsCORONA eravscorona NN cord-253746-15w4gquq 35 35 action action NN cord-253746-15w4gquq 35 36 plan plan NN cord-253746-15w4gquq 35 37 in in IN cord-253746-15w4gquq 35 38 the the DT cord-253746-15w4gquq 35 39 European European NNP cord-253746-15w4gquq 35 40 Union Union NNP cord-253746-15w4gquq 35 41 ( ( -LRB- cord-253746-15w4gquq 35 42 https://bit.ly/2CBKrfb https://bit.ly/2CBKrfb NNP cord-253746-15w4gquq 35 43 ) ) -RRB- cord-253746-15w4gquq 35 44 are be VBP cord-253746-15w4gquq 35 45 highly highly RB cord-253746-15w4gquq 35 46 welcome welcome JJ cord-253746-15w4gquq 35 47 initiatives initiative NNS cord-253746-15w4gquq 35 48 . . . cord-253746-15w4gquq 36 1 Regulators regulator NNS cord-253746-15w4gquq 36 2 have have VBP cord-253746-15w4gquq 36 3 also also RB cord-253746-15w4gquq 36 4 an an DT cord-253746-15w4gquq 36 5 important important JJ cord-253746-15w4gquq 36 6 role role NN cord-253746-15w4gquq 36 7 in in IN cord-253746-15w4gquq 36 8 facilitating facilitate VBG cord-253746-15w4gquq 36 9 the the DT cord-253746-15w4gquq 36 10 implementation implementation NN cord-253746-15w4gquq 36 11 of of IN cord-253746-15w4gquq 36 12 sound sound JJ cord-253746-15w4gquq 36 13 clinical clinical JJ cord-253746-15w4gquq 36 14 trials trial NNS cord-253746-15w4gquq 36 15 for for IN cord-253746-15w4gquq 36 16 COVID-19 COVID-19 NNP cord-253746-15w4gquq 36 17 . . . cord-253746-15w4gquq 37 1 Fortunately fortunately RB cord-253746-15w4gquq 37 2 , , , cord-253746-15w4gquq 37 3 European european JJ cord-253746-15w4gquq 37 4 and and CC cord-253746-15w4gquq 37 5 US US NNP cord-253746-15w4gquq 37 6 regulatory regulatory JJ cord-253746-15w4gquq 37 7 agencies agency NNS cord-253746-15w4gquq 37 8 have have VBP cord-253746-15w4gquq 37 9 issued issue VBN cord-253746-15w4gquq 37 10 guidelines guideline NNS cord-253746-15w4gquq 37 11 for for IN cord-253746-15w4gquq 37 12 clinical clinical JJ cord-253746-15w4gquq 37 13 investigations investigation NNS cord-253746-15w4gquq 37 14 during during IN cord-253746-15w4gquq 37 15 pandemics pandemic NNS cord-253746-15w4gquq 37 16 without without IN cord-253746-15w4gquq 37 17 compromising compromise VBG cord-253746-15w4gquq 37 18 on on IN cord-253746-15w4gquq 37 19 their -PRON- PRP$ cord-253746-15w4gquq 37 20 scientific scientific JJ cord-253746-15w4gquq 37 21 validity validity NN cord-253746-15w4gquq 37 22 and and CC cord-253746-15w4gquq 37 23 ethical ethical JJ cord-253746-15w4gquq 37 24 conduct conduct NN cord-253746-15w4gquq 37 25 ( ( -LRB- cord-253746-15w4gquq 37 26 8) 8) NN cord-253746-15w4gquq 37 27 . . . cord-253746-15w4gquq 38 1 Finally finally RB cord-253746-15w4gquq 38 2 , , , cord-253746-15w4gquq 38 3 as as IN cord-253746-15w4gquq 38 4 discussed discuss VBN cord-253746-15w4gquq 38 5 in in IN cord-253746-15w4gquq 38 6 the the DT cord-253746-15w4gquq 38 7 next next JJ cord-253746-15w4gquq 38 8 section section NN cord-253746-15w4gquq 38 9 , , , cord-253746-15w4gquq 38 10 patients patient NNS cord-253746-15w4gquq 38 11 should should MD cord-253746-15w4gquq 38 12 now now RB cord-253746-15w4gquq 38 13 be be VB cord-253746-15w4gquq 38 14 invited invite VBN cord-253746-15w4gquq 38 15 to to TO cord-253746-15w4gquq 38 16 take take VB cord-253746-15w4gquq 38 17 an an DT cord-253746-15w4gquq 38 18 active active JJ cord-253746-15w4gquq 38 19 role role NN cord-253746-15w4gquq 38 20 in in IN cord-253746-15w4gquq 38 21 the the DT cord-253746-15w4gquq 38 22 design design NN cord-253746-15w4gquq 38 23 of of IN cord-253746-15w4gquq 38 24 COVID-19 COVID-19 NNP cord-253746-15w4gquq 38 25 trials trial NNS cord-253746-15w4gquq 38 26 . . . cord-253746-15w4gquq 39 1 So so RB cord-253746-15w4gquq 39 2 far far RB cord-253746-15w4gquq 39 3 , , , cord-253746-15w4gquq 39 4 patients patient NNS cord-253746-15w4gquq 39 5 enrolled enrol VBN cord-253746-15w4gquq 39 6 in in IN cord-253746-15w4gquq 39 7 the the DT cord-253746-15w4gquq 39 8 trials trial NNS cord-253746-15w4gquq 39 9 mentioned mention VBN cord-253746-15w4gquq 39 10 hereabove hereabove NNP cord-253746-15w4gquq 39 11 did do VBD cord-253746-15w4gquq 39 12 not not RB cord-253746-15w4gquq 39 13 have have VB cord-253746-15w4gquq 39 14 much much JJ cord-253746-15w4gquq 39 15 other other JJ cord-253746-15w4gquq 39 16 option option NN cord-253746-15w4gquq 39 17 than than IN cord-253746-15w4gquq 39 18 signing sign VBG cord-253746-15w4gquq 39 19 the the DT cord-253746-15w4gquq 39 20 informed inform VBN cord-253746-15w4gquq 39 21 - - HYPH cord-253746-15w4gquq 39 22 consent consent NN cord-253746-15w4gquq 39 23 form form NN cord-253746-15w4gquq 39 24 to to TO cord-253746-15w4gquq 39 25 get get VB cord-253746-15w4gquq 39 26 a a DT cord-253746-15w4gquq 39 27 chance chance NN cord-253746-15w4gquq 39 28 to to TO cord-253746-15w4gquq 39 29 receive receive VB cord-253746-15w4gquq 39 30 a a DT cord-253746-15w4gquq 39 31 potentially potentially RB cord-253746-15w4gquq 39 32 life life NN cord-253746-15w4gquq 39 33 - - HYPH cord-253746-15w4gquq 39 34 saving save VBG cord-253746-15w4gquq 39 35 medicine medicine NN cord-253746-15w4gquq 39 36 . . . cord-253746-15w4gquq 40 1 As as IN cord-253746-15w4gquq 40 2 more more JJR cord-253746-15w4gquq 40 3 and and CC cord-253746-15w4gquq 40 4 more more JJR cord-253746-15w4gquq 40 5 patients patient NNS cord-253746-15w4gquq 40 6 will will MD cord-253746-15w4gquq 40 7 be be VB cord-253746-15w4gquq 40 8 diagnosed diagnose VBN cord-253746-15w4gquq 40 9 at at IN cord-253746-15w4gquq 40 10 an an DT cord-253746-15w4gquq 40 11 earlier early JJR cord-253746-15w4gquq 40 12 stage stage NN cord-253746-15w4gquq 40 13 of of IN cord-253746-15w4gquq 40 14 the the DT cord-253746-15w4gquq 40 15 disease disease NN cord-253746-15w4gquq 40 16 or or CC cord-253746-15w4gquq 40 17 with with IN cord-253746-15w4gquq 40 18 a a DT cord-253746-15w4gquq 40 19 milder mild JJR cord-253746-15w4gquq 40 20 form form NN cord-253746-15w4gquq 40 21 of of IN cord-253746-15w4gquq 40 22 COVID-19 COVID-19 NNP cord-253746-15w4gquq 40 23 , , , cord-253746-15w4gquq 40 24 investigators investigator NNS cord-253746-15w4gquq 40 25 will will MD cord-253746-15w4gquq 40 26 have have VB cord-253746-15w4gquq 40 27 to to TO cord-253746-15w4gquq 40 28 ensure ensure VB cord-253746-15w4gquq 40 29 that that IN cord-253746-15w4gquq 40 30 patients patient NNS cord-253746-15w4gquq 40 31 fully fully RB cord-253746-15w4gquq 40 32 understand understand VBP cord-253746-15w4gquq 40 33 and and CC cord-253746-15w4gquq 40 34 adhere adhere VB cord-253746-15w4gquq 40 35 to to IN cord-253746-15w4gquq 40 36 the the DT cord-253746-15w4gquq 40 37 rationale rationale NN cord-253746-15w4gquq 40 38 of of IN cord-253746-15w4gquq 40 39 the the DT cord-253746-15w4gquq 40 40 proposed propose VBN cord-253746-15w4gquq 40 41 trials trial NNS cord-253746-15w4gquq 40 42 , , , cord-253746-15w4gquq 40 43 their -PRON- PRP$ cord-253746-15w4gquq 40 44 expected expect VBN cord-253746-15w4gquq 40 45 benefits benefit NNS cord-253746-15w4gquq 40 46 and and CC cord-253746-15w4gquq 40 47 their -PRON- PRP$ cord-253746-15w4gquq 40 48 potential potential JJ cord-253746-15w4gquq 40 49 risks risk NNS cord-253746-15w4gquq 40 50 . . . cord-253746-15w4gquq 41 1 Patients patient NNS cord-253746-15w4gquq 41 2 ' ' POS cord-253746-15w4gquq 41 3 involvement involvement NN cord-253746-15w4gquq 41 4 in in IN cord-253746-15w4gquq 41 5 medicines medicine NNS cord-253746-15w4gquq 41 6 development development NN cord-253746-15w4gquq 41 7 is be VBZ cord-253746-15w4gquq 41 8 getting get VBG cord-253746-15w4gquq 41 9 more more JJR cord-253746-15w4gquq 41 10 and and CC cord-253746-15w4gquq 41 11 more more RBR cord-253746-15w4gquq 41 12 established established JJ cord-253746-15w4gquq 41 13 in in IN cord-253746-15w4gquq 41 14 both both CC cord-253746-15w4gquq 41 15 academic academic JJ cord-253746-15w4gquq 41 16 and and CC cord-253746-15w4gquq 41 17 industrial industrial JJ cord-253746-15w4gquq 41 18 settings setting NNS cord-253746-15w4gquq 41 19 , , , cord-253746-15w4gquq 41 20 with with IN cord-253746-15w4gquq 41 21 numerous numerous JJ cord-253746-15w4gquq 41 22 publications publication NNS cord-253746-15w4gquq 41 23 showing show VBG cord-253746-15w4gquq 41 24 the the DT cord-253746-15w4gquq 41 25 positive positive JJ cord-253746-15w4gquq 41 26 impact impact NN cord-253746-15w4gquq 41 27 it -PRON- PRP cord-253746-15w4gquq 41 28 might may MD cord-253746-15w4gquq 41 29 have have VB cord-253746-15w4gquq 41 30 ( ( -LRB- cord-253746-15w4gquq 41 31 9 9 CD cord-253746-15w4gquq 41 32 , , , cord-253746-15w4gquq 41 33 10 10 CD cord-253746-15w4gquq 41 34 ) ) -RRB- cord-253746-15w4gquq 41 35 . . . cord-253746-15w4gquq 42 1 The the DT cord-253746-15w4gquq 42 2 European European NNP cord-253746-15w4gquq 42 3 Patient Patient NNP cord-253746-15w4gquq 42 4 Academy Academy NNP cord-253746-15w4gquq 42 5 of of IN cord-253746-15w4gquq 42 6 Therapeutic Therapeutic NNP cord-253746-15w4gquq 42 7 Innovation Innovation NNP cord-253746-15w4gquq 42 8 ( ( -LRB- cord-253746-15w4gquq 42 9 EUPATI EUPATI NNP cord-253746-15w4gquq 42 10 ) ) -RRB- cord-253746-15w4gquq 42 11 launched launch VBN cord-253746-15w4gquq 42 12 by by IN cord-253746-15w4gquq 42 13 the the DT cord-253746-15w4gquq 42 14 Innovative Innovative NNP cord-253746-15w4gquq 42 15 Medicines Medicines NNPS cord-253746-15w4gquq 42 16 Initiative Initiative NNP cord-253746-15w4gquq 42 17 ( ( -LRB- cord-253746-15w4gquq 42 18 IMI IMI NNP cord-253746-15w4gquq 42 19 ) ) -RRB- cord-253746-15w4gquq 42 20 is be VBZ cord-253746-15w4gquq 42 21 an an DT cord-253746-15w4gquq 42 22 example example NN cord-253746-15w4gquq 42 23 of of IN cord-253746-15w4gquq 42 24 a a DT cord-253746-15w4gquq 42 25 successful successful JJ cord-253746-15w4gquq 42 26 consortium consortium NN cord-253746-15w4gquq 42 27 that that WDT cord-253746-15w4gquq 42 28 promotes promote VBZ cord-253746-15w4gquq 42 29 patient patient JJ cord-253746-15w4gquq 42 30 participation participation NN cord-253746-15w4gquq 42 31 across across IN cord-253746-15w4gquq 42 32 various various JJ cord-253746-15w4gquq 42 33 stages stage NNS cord-253746-15w4gquq 42 34 in in IN cord-253746-15w4gquq 42 35 the the DT cord-253746-15w4gquq 42 36 drug drug NN cord-253746-15w4gquq 42 37 development development NN cord-253746-15w4gquq 42 38 lifecycle lifecycle NN cord-253746-15w4gquq 42 39 ( ( -LRB- cord-253746-15w4gquq 42 40 11 11 CD cord-253746-15w4gquq 42 41 ) ) -RRB- cord-253746-15w4gquq 42 42 . . . cord-253746-15w4gquq 43 1 This this DT cord-253746-15w4gquq 43 2 is be VBZ cord-253746-15w4gquq 43 3 essential essential JJ cord-253746-15w4gquq 43 4 to to TO cord-253746-15w4gquq 43 5 ensure ensure VB cord-253746-15w4gquq 43 6 that that IN cord-253746-15w4gquq 43 7 patients patient NNS cord-253746-15w4gquq 43 8 ' ' POS cord-253746-15w4gquq 43 9 expectations expectation NNS cord-253746-15w4gquq 43 10 from from IN cord-253746-15w4gquq 43 11 novel novel JJ cord-253746-15w4gquq 43 12 therapeutics therapeutic NNS cord-253746-15w4gquq 43 13 are be VBP cord-253746-15w4gquq 43 14 at at IN cord-253746-15w4gquq 43 15 the the DT cord-253746-15w4gquq 43 16 center center NN cord-253746-15w4gquq 43 17 of of IN cord-253746-15w4gquq 43 18 trials trial NNS cord-253746-15w4gquq 43 19 ' ' POS cord-253746-15w4gquq 43 20 objectives objective NNS cord-253746-15w4gquq 43 21 . . . cord-253746-15w4gquq 44 1 Now now RB cord-253746-15w4gquq 44 2 is be VBZ cord-253746-15w4gquq 44 3 the the DT cord-253746-15w4gquq 44 4 time time NN cord-253746-15w4gquq 44 5 to to TO cord-253746-15w4gquq 44 6 apply apply VB cord-253746-15w4gquq 44 7 this this DT cord-253746-15w4gquq 44 8 principle principle NN cord-253746-15w4gquq 44 9 in in IN cord-253746-15w4gquq 44 10 the the DT cord-253746-15w4gquq 44 11 search search NN cord-253746-15w4gquq 44 12 for for IN cord-253746-15w4gquq 44 13 novel novel JJ cord-253746-15w4gquq 44 14 treatments treatment NNS cord-253746-15w4gquq 44 15 and and CC cord-253746-15w4gquq 44 16 vaccines vaccine NNS cord-253746-15w4gquq 44 17 against against IN cord-253746-15w4gquq 44 18 COVID-19 COVID-19 NNP cord-253746-15w4gquq 44 19 . . . cord-253746-15w4gquq 45 1 Facing face VBG cord-253746-15w4gquq 45 2 the the DT cord-253746-15w4gquq 45 3 tsunami tsunami NN cord-253746-15w4gquq 45 4 of of IN cord-253746-15w4gquq 45 5 informations information NNS cord-253746-15w4gquq 45 6 becoming become VBG cord-253746-15w4gquq 45 7 available available JJ cord-253746-15w4gquq 45 8 every every DT cord-253746-15w4gquq 45 9 day day NN cord-253746-15w4gquq 45 10 about about IN cord-253746-15w4gquq 45 11 SARS SARS NNP cord-253746-15w4gquq 45 12 - - HYPH cord-253746-15w4gquq 45 13 CoV-2 CoV-2 NNP cord-253746-15w4gquq 45 14 and and CC cord-253746-15w4gquq 45 15 COVID-19 COVID-19 NNP cord-253746-15w4gquq 45 16 , , , cord-253746-15w4gquq 45 17 patients patient NNS cord-253746-15w4gquq 45 18 ' ' POS cord-253746-15w4gquq 45 19 input input NN cord-253746-15w4gquq 45 20 is be VBZ cord-253746-15w4gquq 45 21 also also RB cord-253746-15w4gquq 45 22 essential essential JJ cord-253746-15w4gquq 45 23 to to TO cord-253746-15w4gquq 45 24 determine determine VB cord-253746-15w4gquq 45 25 what what WDT cord-253746-15w4gquq 45 26 type type NN cord-253746-15w4gquq 45 27 of of IN cord-253746-15w4gquq 45 28 information information NN cord-253746-15w4gquq 45 29 is be VBZ cord-253746-15w4gquq 45 30 relevant relevant JJ cord-253746-15w4gquq 45 31 and and CC cord-253746-15w4gquq 45 32 how how WRB cord-253746-15w4gquq 45 33 it -PRON- PRP cord-253746-15w4gquq 45 34 should should MD cord-253746-15w4gquq 45 35 be be VB cord-253746-15w4gquq 45 36 communicated communicate VBN cord-253746-15w4gquq 45 37 ( ( -LRB- cord-253746-15w4gquq 45 38 12 12 CD cord-253746-15w4gquq 45 39 ) ) -RRB- cord-253746-15w4gquq 45 40 . . . cord-253746-15w4gquq 46 1 In in IN cord-253746-15w4gquq 46 2 order order NN cord-253746-15w4gquq 46 3 to to TO cord-253746-15w4gquq 46 4 take take VB cord-253746-15w4gquq 46 5 advantage advantage NN cord-253746-15w4gquq 46 6 of of IN cord-253746-15w4gquq 46 7 the the DT cord-253746-15w4gquq 46 8 current current JJ cord-253746-15w4gquq 46 9 window window NN cord-253746-15w4gquq 46 10 of of IN cord-253746-15w4gquq 46 11 opportunity opportunity NN cord-253746-15w4gquq 46 12 for for IN cord-253746-15w4gquq 46 13 patient patient NN cord-253746-15w4gquq 46 14 's 's POS cord-253746-15w4gquq 46 15 involvement involvement NN cord-253746-15w4gquq 46 16 in in IN cord-253746-15w4gquq 46 17 the the DT cord-253746-15w4gquq 46 18 fight fight NN cord-253746-15w4gquq 46 19 against against IN cord-253746-15w4gquq 46 20 COVID-19 COVID-19 NNP cord-253746-15w4gquq 46 21 pandemic pandemic NN cord-253746-15w4gquq 46 22 , , , cord-253746-15w4gquq 46 23 one one PRP cord-253746-15w4gquq 46 24 should should MD cord-253746-15w4gquq 46 25 consider consider VB cord-253746-15w4gquq 46 26 the the DT cord-253746-15w4gquq 46 27 various various JJ cord-253746-15w4gquq 46 28 phases phase NNS cord-253746-15w4gquq 46 29 of of IN cord-253746-15w4gquq 46 30 the the DT cord-253746-15w4gquq 46 31 patient patient NN cord-253746-15w4gquq 46 32 journey journey NN cord-253746-15w4gquq 46 33 , , , cord-253746-15w4gquq 46 34 from from IN cord-253746-15w4gquq 46 35 the the DT cord-253746-15w4gquq 46 36 pre pre JJ cord-253746-15w4gquq 46 37 - - JJ cord-253746-15w4gquq 46 38 symptomatic symptomatic JJ cord-253746-15w4gquq 46 39 phase phase NN cord-253746-15w4gquq 46 40 up up IN cord-253746-15w4gquq 46 41 to to IN cord-253746-15w4gquq 46 42 recovery recovery NN cord-253746-15w4gquq 46 43 and and CC cord-253746-15w4gquq 46 44 beyond beyond IN cord-253746-15w4gquq 46 45 . . . cord-253746-15w4gquq 47 1 The the DT cord-253746-15w4gquq 47 2 multisystemic multisystemic JJ cord-253746-15w4gquq 47 3 consequences consequence NNS cord-253746-15w4gquq 47 4 of of IN cord-253746-15w4gquq 47 5 SARS SARS NNP cord-253746-15w4gquq 47 6 - - HYPH cord-253746-15w4gquq 47 7 CoV-2 CoV-2 NNP cord-253746-15w4gquq 47 8 infection infection NN cord-253746-15w4gquq 47 9 complexifies complexify VBZ cord-253746-15w4gquq 47 10 patient patient JJ cord-253746-15w4gquq 47 11 stratification stratification NN cord-253746-15w4gquq 47 12 and and CC cord-253746-15w4gquq 47 13 delineation delineation NN cord-253746-15w4gquq 47 14 of of IN cord-253746-15w4gquq 47 15 patient patient JJ cord-253746-15w4gquq 47 16 preferences preference NNS cord-253746-15w4gquq 47 17 . . . cord-253746-15w4gquq 48 1 Furthermore furthermore RB cord-253746-15w4gquq 48 2 , , , cord-253746-15w4gquq 48 3 patient patient NN cord-253746-15w4gquq 48 4 reported report VBN cord-253746-15w4gquq 48 5 outcomes outcome NNS cord-253746-15w4gquq 48 6 are be VBP cord-253746-15w4gquq 48 7 essential essential JJ cord-253746-15w4gquq 48 8 to to TO cord-253746-15w4gquq 48 9 assess assess VB cord-253746-15w4gquq 48 10 the the DT cord-253746-15w4gquq 48 11 impact impact NN cord-253746-15w4gquq 48 12 of of IN cord-253746-15w4gquq 48 13 therapeutic therapeutic JJ cord-253746-15w4gquq 48 14 interventions intervention NNS cord-253746-15w4gquq 48 15 on on IN cord-253746-15w4gquq 48 16 the the DT cord-253746-15w4gquq 48 17 long long JJ cord-253746-15w4gquq 48 18 - - HYPH cord-253746-15w4gquq 48 19 term term NN cord-253746-15w4gquq 48 20 consequences consequence NNS cord-253746-15w4gquq 48 21 of of IN cord-253746-15w4gquq 48 22 COVID-19 COVID-19 NNP cord-253746-15w4gquq 48 23 ( ( -LRB- cord-253746-15w4gquq 48 24 13 13 CD cord-253746-15w4gquq 48 25 ) ) -RRB- cord-253746-15w4gquq 48 26 . . . cord-253746-15w4gquq 49 1 It -PRON- PRP cord-253746-15w4gquq 49 2 is be VBZ cord-253746-15w4gquq 49 3 therefore therefore RB cord-253746-15w4gquq 49 4 important important JJ cord-253746-15w4gquq 49 5 that that IN cord-253746-15w4gquq 49 6 patient patient JJ cord-253746-15w4gquq 49 7 organizations organization NNS cord-253746-15w4gquq 49 8 are be VBP cord-253746-15w4gquq 49 9 involved involve VBN cord-253746-15w4gquq 49 10 early early RB cord-253746-15w4gquq 49 11 on on RB cord-253746-15w4gquq 49 12 in in IN cord-253746-15w4gquq 49 13 the the DT cord-253746-15w4gquq 49 14 design design NN cord-253746-15w4gquq 49 15 of of IN cord-253746-15w4gquq 49 16 clinical clinical JJ cord-253746-15w4gquq 49 17 trials trial NNS cord-253746-15w4gquq 49 18 . . . cord-253746-15w4gquq 50 1 Finally finally RB cord-253746-15w4gquq 50 2 , , , cord-253746-15w4gquq 50 3 as as IN cord-253746-15w4gquq 50 4 compared compare VBN cord-253746-15w4gquq 50 5 to to IN cord-253746-15w4gquq 50 6 medical medical JJ cord-253746-15w4gquq 50 7 interventions intervention NNS cord-253746-15w4gquq 50 8 for for IN cord-253746-15w4gquq 50 9 other other JJ cord-253746-15w4gquq 50 10 diseases disease NNS cord-253746-15w4gquq 50 11 , , , cord-253746-15w4gquq 50 12 one one PRP cord-253746-15w4gquq 50 13 should should MD cord-253746-15w4gquq 50 14 keep keep VB cord-253746-15w4gquq 50 15 in in IN cord-253746-15w4gquq 50 16 mind mind NN cord-253746-15w4gquq 50 17 that that IN cord-253746-15w4gquq 50 18 during during IN cord-253746-15w4gquq 50 19 a a DT cord-253746-15w4gquq 50 20 pandemic pandemic NN cord-253746-15w4gquq 50 21 every every DT cord-253746-15w4gquq 50 22 citizen citizen NN cord-253746-15w4gquq 50 23 can can MD cord-253746-15w4gquq 50 24 become become VB cord-253746-15w4gquq 50 25 a a DT cord-253746-15w4gquq 50 26 patient patient NN cord-253746-15w4gquq 50 27 from from IN cord-253746-15w4gquq 50 28 1 1 CD cord-253746-15w4gquq 50 29 day day NN cord-253746-15w4gquq 50 30 to to IN cord-253746-15w4gquq 50 31 the the DT cord-253746-15w4gquq 50 32 other other JJ cord-253746-15w4gquq 50 33 . . . cord-253746-15w4gquq 51 1 This this DT cord-253746-15w4gquq 51 2 has have VBZ cord-253746-15w4gquq 51 3 impact impact NN cord-253746-15w4gquq 51 4 on on IN cord-253746-15w4gquq 51 5 both both CC cord-253746-15w4gquq 51 6 clinical clinical JJ cord-253746-15w4gquq 51 7 trial trial NN cord-253746-15w4gquq 51 8 recruitments recruitment NNS cord-253746-15w4gquq 51 9 and and CC cord-253746-15w4gquq 51 10 behavioral behavioral JJ cord-253746-15w4gquq 51 11 interventions intervention NNS cord-253746-15w4gquq 51 12 to to TO cord-253746-15w4gquq 51 13 reduce reduce VB cord-253746-15w4gquq 51 14 the the DT cord-253746-15w4gquq 51 15 spread spread NN cord-253746-15w4gquq 51 16 of of IN cord-253746-15w4gquq 51 17 the the DT cord-253746-15w4gquq 51 18 disease disease NN cord-253746-15w4gquq 51 19 , , , cord-253746-15w4gquq 51 20 since since IN cord-253746-15w4gquq 51 21 healthy healthy JJ cord-253746-15w4gquq 51 22 people people NNS cord-253746-15w4gquq 51 23 need need VBP cord-253746-15w4gquq 51 24 stronger strong JJR cord-253746-15w4gquq 51 25 incentives incentive NNS cord-253746-15w4gquq 51 26 as as IN cord-253746-15w4gquq 51 27 compared compare VBN cord-253746-15w4gquq 51 28 to to IN cord-253746-15w4gquq 51 29 patients patient NNS cord-253746-15w4gquq 51 30 . . . cord-253746-15w4gquq 52 1 This this DT cord-253746-15w4gquq 52 2 is be VBZ cord-253746-15w4gquq 52 3 especially especially RB cord-253746-15w4gquq 52 4 important important JJ cord-253746-15w4gquq 52 5 to to TO cord-253746-15w4gquq 52 6 ensure ensure VB cord-253746-15w4gquq 52 7 adequate adequate JJ cord-253746-15w4gquq 52 8 vaccine vaccine NN cord-253746-15w4gquq 52 9 coverage coverage NN cord-253746-15w4gquq 52 10 in in IN cord-253746-15w4gquq 52 11 an an DT cord-253746-15w4gquq 52 12 era era NN cord-253746-15w4gquq 52 13 in in IN cord-253746-15w4gquq 52 14 which which WDT cord-253746-15w4gquq 52 15 anti anti JJ cord-253746-15w4gquq 52 16 - - JJ cord-253746-15w4gquq 52 17 vaxx vaxx JJ cord-253746-15w4gquq 52 18 movements movement NNS cord-253746-15w4gquq 52 19 are be VBP cord-253746-15w4gquq 52 20 very very RB cord-253746-15w4gquq 52 21 active active JJ cord-253746-15w4gquq 52 22 and and CC cord-253746-15w4gquq 52 23 vaccine vaccine NN cord-253746-15w4gquq 52 24 hesitancy hesitancy NN cord-253746-15w4gquq 52 25 is be VBZ cord-253746-15w4gquq 52 26 prevalent prevalent JJ cord-253746-15w4gquq 52 27 . . . cord-253746-15w4gquq 53 1 Fostering foster VBG cord-253746-15w4gquq 53 2 health health NN cord-253746-15w4gquq 53 3 literacy literacy NN cord-253746-15w4gquq 53 4 in in IN cord-253746-15w4gquq 53 5 the the DT cord-253746-15w4gquq 53 6 wider wide JJR cord-253746-15w4gquq 53 7 public public NN cord-253746-15w4gquq 53 8 should should MD cord-253746-15w4gquq 53 9 therefore therefore RB cord-253746-15w4gquq 53 10 closely closely RB cord-253746-15w4gquq 53 11 be be VB cord-253746-15w4gquq 53 12 associated associate VBN cord-253746-15w4gquq 53 13 with with IN cord-253746-15w4gquq 53 14 patient patient JJ cord-253746-15w4gquq 53 15 empowerment empowerment NN cord-253746-15w4gquq 53 16 in in IN cord-253746-15w4gquq 53 17 the the DT cord-253746-15w4gquq 53 18 collective collective JJ cord-253746-15w4gquq 53 19 fight fight NN cord-253746-15w4gquq 53 20 against against IN cord-253746-15w4gquq 53 21 COVID-19 COVID-19 NNP cord-253746-15w4gquq 53 22 . . . cord-253746-15w4gquq 54 1 The the DT cord-253746-15w4gquq 54 2 original original JJ cord-253746-15w4gquq 54 3 contributions contribution NNS cord-253746-15w4gquq 54 4 presented present VBN cord-253746-15w4gquq 54 5 in in IN cord-253746-15w4gquq 54 6 the the DT cord-253746-15w4gquq 54 7 study study NN cord-253746-15w4gquq 54 8 are be VBP cord-253746-15w4gquq 54 9 included include VBN cord-253746-15w4gquq 54 10 in in IN cord-253746-15w4gquq 54 11 the the DT cord-253746-15w4gquq 54 12 article article NN cord-253746-15w4gquq 54 13 / / SYM cord-253746-15w4gquq 54 14 supplementary supplementary JJ cord-253746-15w4gquq 54 15 material material NN cord-253746-15w4gquq 54 16 , , , cord-253746-15w4gquq 54 17 further further JJ cord-253746-15w4gquq 54 18 inquiries inquiry NNS cord-253746-15w4gquq 54 19 can can MD cord-253746-15w4gquq 54 20 be be VB cord-253746-15w4gquq 54 21 directed direct VBN cord-253746-15w4gquq 54 22 to to IN cord-253746-15w4gquq 54 23 the the DT cord-253746-15w4gquq 54 24 corresponding correspond VBG cord-253746-15w4gquq 54 25 author author NN cord-253746-15w4gquq 54 26 / / SYM cord-253746-15w4gquq 54 27 s s NN cord-253746-15w4gquq 54 28 . . . cord-253746-15w4gquq 55 1 Accelerating accelerate VBG cord-253746-15w4gquq 55 2 COVID-19 COVID-19 NNP cord-253746-15w4gquq 55 3 Therapeutic Therapeutic NNP cord-253746-15w4gquq 55 4 Interventions Interventions NNPS cord-253746-15w4gquq 55 5 and and CC cord-253746-15w4gquq 55 6 Vaccines Vaccines NNPS cord-253746-15w4gquq 55 7 ( ( -LRB- cord-253746-15w4gquq 55 8 ACTIV ACTIV NNP cord-253746-15w4gquq 55 9 ) ) -RRB- cord-253746-15w4gquq 56 1 Flooded flood VBN cord-253746-15w4gquq 56 2 by by IN cord-253746-15w4gquq 56 3 the the DT cord-253746-15w4gquq 56 4 torrent torrent NN cord-253746-15w4gquq 56 5 : : : cord-253746-15w4gquq 56 6 the the DT cord-253746-15w4gquq 56 7 COVID COVID NNP cord-253746-15w4gquq 56 8 19 19 CD cord-253746-15w4gquq 56 9 drug drug NN cord-253746-15w4gquq 56 10 pipeline pipeline NN cord-253746-15w4gquq 56 11 Clinical clinical JJ cord-253746-15w4gquq 56 12 trials trial NNS cord-253746-15w4gquq 56 13 of of IN cord-253746-15w4gquq 56 14 disease disease NN cord-253746-15w4gquq 56 15 stages stage NNS cord-253746-15w4gquq 56 16 in in IN cord-253746-15w4gquq 56 17 COVID COVID NNP cord-253746-15w4gquq 56 18 19 19 CD cord-253746-15w4gquq 56 19 : : : cord-253746-15w4gquq 56 20 complicated complicated JJ cord-253746-15w4gquq 56 21 and and CC cord-253746-15w4gquq 56 22 often often RB cord-253746-15w4gquq 56 23 misinterpreted misinterpret VBD cord-253746-15w4gquq 56 24 A a DT cord-253746-15w4gquq 56 25 Bayesian bayesian JJ cord-253746-15w4gquq 56 26 adaptive adaptive JJ cord-253746-15w4gquq 56 27 design design NN cord-253746-15w4gquq 56 28 for for IN cord-253746-15w4gquq 56 29 biomarker biomarker NN cord-253746-15w4gquq 56 30 trials trial NNS cord-253746-15w4gquq 56 31 with with IN cord-253746-15w4gquq 56 32 linked link VBN cord-253746-15w4gquq 56 33 treatments treatment NNS cord-253746-15w4gquq 56 34 The the DT cord-253746-15w4gquq 56 35 Recovery Recovery NNP cord-253746-15w4gquq 56 36 Collaborative Collaborative NNP cord-253746-15w4gquq 56 37 Group Group NNP cord-253746-15w4gquq 56 38 . . . cord-253746-15w4gquq 57 1 Effect effect NN cord-253746-15w4gquq 57 2 of of IN cord-253746-15w4gquq 57 3 dexamethasone dexamethasone NN cord-253746-15w4gquq 57 4 in in IN cord-253746-15w4gquq 57 5 hospitalized hospitalize VBN cord-253746-15w4gquq 57 6 patients patient NNS cord-253746-15w4gquq 57 7 with with IN cord-253746-15w4gquq 57 8 COVID-19 covid-19 JJ cord-253746-15w4gquq 57 9 ; ; : cord-253746-15w4gquq 57 10 preliminary preliminary JJ cord-253746-15w4gquq 57 11 report report NN cord-253746-15w4gquq 57 12 Remdesivir Remdesivir NNP cord-253746-15w4gquq 57 13 for for IN cord-253746-15w4gquq 57 14 the the DT cord-253746-15w4gquq 57 15 treatment treatment NN cord-253746-15w4gquq 57 16 of of IN cord-253746-15w4gquq 57 17 Covid-19 Covid-19 NNP cord-253746-15w4gquq 57 18 -Preliminary -Preliminary NNP cord-253746-15w4gquq 57 19 report report NN cord-253746-15w4gquq 57 20 Research Research NNP cord-253746-15w4gquq 57 21 in in IN cord-253746-15w4gquq 57 22 the the DT cord-253746-15w4gquq 57 23 context context NN cord-253746-15w4gquq 57 24 of of IN cord-253746-15w4gquq 57 25 a a DT cord-253746-15w4gquq 57 26 pandemic pandemic NN cord-253746-15w4gquq 57 27 Clinical clinical JJ cord-253746-15w4gquq 57 28 trials trial NNS cord-253746-15w4gquq 57 29 for for IN cord-253746-15w4gquq 57 30 Covid-19 covid-19 NN cord-253746-15w4gquq 57 31 : : : cord-253746-15w4gquq 57 32 can can MD cord-253746-15w4gquq 57 33 we -PRON- PRP cord-253746-15w4gquq 57 34 better well JJR cord-253746-15w4gquq 57 35 use use VB cord-253746-15w4gquq 57 36 the the DT cord-253746-15w4gquq 57 37 short short JJ cord-253746-15w4gquq 57 38 window window NN cord-253746-15w4gquq 57 39 of of IN cord-253746-15w4gquq 57 40 opportunity opportunity NN cord-253746-15w4gquq 57 41 ? ? . cord-253746-15w4gquq 58 1 Assessing assess VBG cord-253746-15w4gquq 58 2 the the DT cord-253746-15w4gquq 58 3 financial financial JJ cord-253746-15w4gquq 58 4 value value NN cord-253746-15w4gquq 58 5 of of IN cord-253746-15w4gquq 58 6 patient patient NN cord-253746-15w4gquq 58 7 engagement engagement NN cord-253746-15w4gquq 58 8 : : : cord-253746-15w4gquq 58 9 a a DT cord-253746-15w4gquq 58 10 quantitative quantitative JJ cord-253746-15w4gquq 58 11 approach approach NN cord-253746-15w4gquq 58 12 from from IN cord-253746-15w4gquq 58 13 CTTI CTTI NNP cord-253746-15w4gquq 58 14 's 's POS cord-253746-15w4gquq 58 15 patient patient NN cord-253746-15w4gquq 58 16 groups group NNS cord-253746-15w4gquq 58 17 and and CC cord-253746-15w4gquq 58 18 clinical clinical JJ cord-253746-15w4gquq 58 19 trials trial NNS cord-253746-15w4gquq 58 20 project project VBP cord-253746-15w4gquq 58 21 Measuring measure VBG cord-253746-15w4gquq 58 22 the the DT cord-253746-15w4gquq 58 23 impact impact NN cord-253746-15w4gquq 58 24 of of IN cord-253746-15w4gquq 58 25 patient patient JJ cord-253746-15w4gquq 58 26 engagement engagement NN cord-253746-15w4gquq 58 27 and and CC cord-253746-15w4gquq 58 28 patient patient JJ cord-253746-15w4gquq 58 29 centricity centricity NN cord-253746-15w4gquq 58 30 in in IN cord-253746-15w4gquq 58 31 clinical clinical JJ cord-253746-15w4gquq 58 32 research research NN cord-253746-15w4gquq 58 33 and and CC cord-253746-15w4gquq 58 34 development development NN cord-253746-15w4gquq 58 35 Improving improve VBG cord-253746-15w4gquq 58 36 patient patient JJ cord-253746-15w4gquq 58 37 involvement involvement NN cord-253746-15w4gquq 58 38 in in IN cord-253746-15w4gquq 58 39 medicines medicine NNS cord-253746-15w4gquq 58 40 research research NN cord-253746-15w4gquq 58 41 and and CC cord-253746-15w4gquq 58 42 development development NN cord-253746-15w4gquq 58 43 : : : cord-253746-15w4gquq 58 44 : : : cord-253746-15w4gquq 58 45 a a DT cord-253746-15w4gquq 58 46 practical practical JJ cord-253746-15w4gquq 58 47 roadmap roadmap NN cord-253746-15w4gquq 58 48 Improving improve VBG cord-253746-15w4gquq 58 49 clinical clinical JJ cord-253746-15w4gquq 58 50 trial trial NN cord-253746-15w4gquq 58 51 enrollment enrollment NN cord-253746-15w4gquq 58 52 -In -In : cord-253746-15w4gquq 58 53 the the DT cord-253746-15w4gquq 58 54 Covid-19 covid-19 NN cord-253746-15w4gquq 58 55 era era NN cord-253746-15w4gquq 58 56 and and CC cord-253746-15w4gquq 58 57 beyond beyond IN cord-253746-15w4gquq 58 58 Patient patient NN cord-253746-15w4gquq 58 59 - - HYPH cord-253746-15w4gquq 58 60 reported report VBN cord-253746-15w4gquq 58 61 outcomes outcome NNS cord-253746-15w4gquq 58 62 : : : cord-253746-15w4gquq 58 63 central central JJ cord-253746-15w4gquq 58 64 to to IN cord-253746-15w4gquq 58 65 the the DT cord-253746-15w4gquq 58 66 management management NN cord-253746-15w4gquq 58 67 of of IN cord-253746-15w4gquq 58 68 COVID-19 COVID-19 NNP cord-253746-15w4gquq 58 69 All all DT cord-253746-15w4gquq 58 70 authors author NNS cord-253746-15w4gquq 58 71 listed list VBN cord-253746-15w4gquq 58 72 have have VBP cord-253746-15w4gquq 58 73 made make VBN cord-253746-15w4gquq 58 74 a a DT cord-253746-15w4gquq 58 75 substantial substantial JJ cord-253746-15w4gquq 58 76 , , , cord-253746-15w4gquq 58 77 direct direct JJ cord-253746-15w4gquq 58 78 and and CC cord-253746-15w4gquq 58 79 intellectual intellectual JJ cord-253746-15w4gquq 58 80 contribution contribution NN cord-253746-15w4gquq 58 81 to to IN cord-253746-15w4gquq 58 82 the the DT cord-253746-15w4gquq 58 83 work work NN cord-253746-15w4gquq 58 84 , , , cord-253746-15w4gquq 58 85 and and CC cord-253746-15w4gquq 58 86 approved approve VBD cord-253746-15w4gquq 58 87 it -PRON- PRP cord-253746-15w4gquq 58 88 for for IN cord-253746-15w4gquq 58 89 publication publication NN cord-253746-15w4gquq 58 90 . . . cord-253746-15w4gquq 59 1 The the DT cord-253746-15w4gquq 59 2 authors author NNS cord-253746-15w4gquq 59 3 declare declare VBP cord-253746-15w4gquq 59 4 that that IN cord-253746-15w4gquq 59 5 the the DT cord-253746-15w4gquq 59 6 research research NN cord-253746-15w4gquq 59 7 was be VBD cord-253746-15w4gquq 59 8 conducted conduct VBN cord-253746-15w4gquq 59 9 in in IN cord-253746-15w4gquq 59 10 the the DT cord-253746-15w4gquq 59 11 absence absence NN cord-253746-15w4gquq 59 12 of of IN cord-253746-15w4gquq 59 13 any any DT cord-253746-15w4gquq 59 14 commercial commercial JJ cord-253746-15w4gquq 59 15 or or CC cord-253746-15w4gquq 59 16 financial financial JJ cord-253746-15w4gquq 59 17 relationships relationship NNS cord-253746-15w4gquq 59 18 that that WDT cord-253746-15w4gquq 59 19 could could MD cord-253746-15w4gquq 59 20 be be VB cord-253746-15w4gquq 59 21 construed construe VBN cord-253746-15w4gquq 59 22 as as IN cord-253746-15w4gquq 59 23 a a DT cord-253746-15w4gquq 59 24 potential potential JJ cord-253746-15w4gquq 59 25 conflict conflict NN cord-253746-15w4gquq 59 26 of of IN cord-253746-15w4gquq 59 27 interest interest NN cord-253746-15w4gquq 59 28 . . . cord-253746-15w4gquq 60 1 Copyright copyright NN cord-253746-15w4gquq 60 2 © © NNP cord-253746-15w4gquq 60 3 2020 2020 CD cord-253746-15w4gquq 60 4 Goldman Goldman NNP cord-253746-15w4gquq 60 5 and and CC cord-253746-15w4gquq 60 6 Silva Silva NNP cord-253746-15w4gquq 60 7 . . . cord-253746-15w4gquq 61 1 This this DT cord-253746-15w4gquq 61 2 is be VBZ cord-253746-15w4gquq 61 3 an an DT cord-253746-15w4gquq 61 4 open open JJ cord-253746-15w4gquq 61 5 - - HYPH cord-253746-15w4gquq 61 6 access access NN cord-253746-15w4gquq 61 7 article article NN cord-253746-15w4gquq 61 8 distributed distribute VBN cord-253746-15w4gquq 61 9 under under IN cord-253746-15w4gquq 61 10 the the DT cord-253746-15w4gquq 61 11 terms term NNS cord-253746-15w4gquq 61 12 of of IN cord-253746-15w4gquq 61 13 the the DT cord-253746-15w4gquq 61 14 Creative Creative NNP cord-253746-15w4gquq 61 15 Commons Commons NNP cord-253746-15w4gquq 61 16 Attribution Attribution NNP cord-253746-15w4gquq 61 17 License License NNP cord-253746-15w4gquq 61 18 ( ( -LRB- cord-253746-15w4gquq 61 19 CC CC NNP cord-253746-15w4gquq 61 20 BY BY NNP cord-253746-15w4gquq 61 21 ) ) -RRB- cord-253746-15w4gquq 61 22 . . . cord-253746-15w4gquq 62 1 The the DT cord-253746-15w4gquq 62 2 use use NN cord-253746-15w4gquq 62 3 , , , cord-253746-15w4gquq 62 4 distribution distribution NN cord-253746-15w4gquq 62 5 or or CC cord-253746-15w4gquq 62 6 reproduction reproduction NN cord-253746-15w4gquq 62 7 in in IN cord-253746-15w4gquq 62 8 other other JJ cord-253746-15w4gquq 62 9 forums forum NNS cord-253746-15w4gquq 62 10 is be VBZ cord-253746-15w4gquq 62 11 permitted permit VBN cord-253746-15w4gquq 62 12 , , , cord-253746-15w4gquq 62 13 provided provide VBD cord-253746-15w4gquq 62 14 the the DT cord-253746-15w4gquq 62 15 original original JJ cord-253746-15w4gquq 62 16 author(s author(s NNP cord-253746-15w4gquq 62 17 ) ) -RRB- cord-253746-15w4gquq 62 18 and and CC cord-253746-15w4gquq 62 19 the the DT cord-253746-15w4gquq 62 20 copyright copyright NN cord-253746-15w4gquq 62 21 owner(s owner(s NNP cord-253746-15w4gquq 62 22 ) ) -RRB- cord-253746-15w4gquq 62 23 are be VBP cord-253746-15w4gquq 62 24 credited credit VBN cord-253746-15w4gquq 62 25 and and CC cord-253746-15w4gquq 62 26 that that IN cord-253746-15w4gquq 62 27 the the DT cord-253746-15w4gquq 62 28 original original JJ cord-253746-15w4gquq 62 29 publication publication NN cord-253746-15w4gquq 62 30 in in IN cord-253746-15w4gquq 62 31 this this DT cord-253746-15w4gquq 62 32 journal journal NN cord-253746-15w4gquq 62 33 is be VBZ cord-253746-15w4gquq 62 34 cited cite VBN cord-253746-15w4gquq 62 35 , , , cord-253746-15w4gquq 62 36 in in IN cord-253746-15w4gquq 62 37 accordance accordance NN cord-253746-15w4gquq 62 38 with with IN cord-253746-15w4gquq 62 39 accepted accepted JJ cord-253746-15w4gquq 62 40 academic academic JJ cord-253746-15w4gquq 62 41 practice practice NN cord-253746-15w4gquq 62 42 . . . cord-253746-15w4gquq 63 1 No no DT cord-253746-15w4gquq 63 2 use use NN cord-253746-15w4gquq 63 3 , , , cord-253746-15w4gquq 63 4 distribution distribution NN cord-253746-15w4gquq 63 5 or or CC cord-253746-15w4gquq 63 6 reproduction reproduction NN cord-253746-15w4gquq 63 7 is be VBZ cord-253746-15w4gquq 63 8 permitted permit VBN cord-253746-15w4gquq 63 9 which which WDT cord-253746-15w4gquq 63 10 does do VBZ cord-253746-15w4gquq 63 11 not not RB cord-253746-15w4gquq 63 12 comply comply VB cord-253746-15w4gquq 63 13 with with IN cord-253746-15w4gquq 63 14 these these DT cord-253746-15w4gquq 63 15 terms term NNS cord-253746-15w4gquq 63 16 . . .