id sid tid token lemma pos cord-035067-ic843wr9 1 1 key key NN cord-035067-ic843wr9 1 2 : : : cord-035067-ic843wr9 1 3 cord-035067-ic843wr9 cord-035067-ic843wr9 . cord-035067-ic843wr9 2 1 authors author NNS cord-035067-ic843wr9 2 2 : : : cord-035067-ic843wr9 2 3 de de NNP cord-035067-ic843wr9 2 4 Almeida Almeida NNP cord-035067-ic843wr9 2 5 , , , cord-035067-ic843wr9 2 6 Joana Joana NNP cord-035067-ic843wr9 2 7 Ferro Ferro NNP cord-035067-ic843wr9 2 8 Machado Machado NNP cord-035067-ic843wr9 2 9 ; ; : cord-035067-ic843wr9 2 10 Chehter Chehter NNP cord-035067-ic843wr9 2 11 , , , cord-035067-ic843wr9 2 12 Ethel Ethel NNP cord-035067-ic843wr9 2 13 Zimberg Zimberg NNP cord-035067-ic843wr9 3 1 title title NN cord-035067-ic843wr9 3 2 : : : cord-035067-ic843wr9 3 3 COVID-19 covid-19 VB cord-035067-ic843wr9 3 4 and and CC cord-035067-ic843wr9 3 5 the the DT cord-035067-ic843wr9 3 6 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 3 7 tract tract NN cord-035067-ic843wr9 3 8 : : : cord-035067-ic843wr9 3 9 what what WP cord-035067-ic843wr9 3 10 do do VBP cord-035067-ic843wr9 3 11 we -PRON- PRP cord-035067-ic843wr9 3 12 already already RB cord-035067-ic843wr9 3 13 know know VB cord-035067-ic843wr9 3 14 ? ? . cord-035067-ic843wr9 4 1 date date NN cord-035067-ic843wr9 4 2 : : : cord-035067-ic843wr9 4 3 2020 2020 CD cord-035067-ic843wr9 4 4 - - HYPH cord-035067-ic843wr9 4 5 11 11 CD cord-035067-ic843wr9 4 6 - - HYPH cord-035067-ic843wr9 4 7 05 05 CD cord-035067-ic843wr9 4 8 journal journal NN cord-035067-ic843wr9 4 9 : : : cord-035067-ic843wr9 5 1 nan nan NNP cord-035067-ic843wr9 5 2 DOI DOI NNP cord-035067-ic843wr9 5 3 : : : cord-035067-ic843wr9 6 1 10.31744 10.31744 CD cord-035067-ic843wr9 6 2 / / SYM cord-035067-ic843wr9 6 3 einstein_journal/2020rw5909 einstein_journal/2020rw5909 JJ cord-035067-ic843wr9 6 4 sha sha NNP cord-035067-ic843wr9 6 5 : : : cord-035067-ic843wr9 6 6 fa9f591b6d686e71d4d2c3ee1d0608b1ed68f817 fa9f591b6d686e71d4d2c3ee1d0608b1ed68f817 NNP cord-035067-ic843wr9 6 7 doc_id doc_id CD cord-035067-ic843wr9 6 8 : : : cord-035067-ic843wr9 7 1 35067 35067 CD cord-035067-ic843wr9 7 2 cord_uid cord_uid NNS cord-035067-ic843wr9 7 3 : : : cord-035067-ic843wr9 8 1 ic843wr9 ic843wr9 NNP cord-035067-ic843wr9 9 1 The the DT cord-035067-ic843wr9 9 2 new new JJ cord-035067-ic843wr9 9 3 coronavirus coronavirus NN cord-035067-ic843wr9 9 4 disease disease NN cord-035067-ic843wr9 9 5 pandemic pandemic NN cord-035067-ic843wr9 9 6 is be VBZ cord-035067-ic843wr9 9 7 defining define VBG cord-035067-ic843wr9 9 8 2020 2020 CD cord-035067-ic843wr9 9 9 , , , cord-035067-ic843wr9 9 10 with with IN cord-035067-ic843wr9 9 11 almost almost RB cord-035067-ic843wr9 9 12 17.5 17.5 CD cord-035067-ic843wr9 9 13 million million CD cord-035067-ic843wr9 9 14 infected infect VBN cord-035067-ic843wr9 9 15 individuals individual NNS cord-035067-ic843wr9 9 16 and and CC cord-035067-ic843wr9 9 17 700 700 CD cord-035067-ic843wr9 9 18 thousand thousand CD cord-035067-ic843wr9 9 19 deaths death NNS cord-035067-ic843wr9 9 20 up up RB cord-035067-ic843wr9 9 21 to to IN cord-035067-ic843wr9 9 22 beginning beginning NN cord-035067-ic843wr9 9 23 of of IN cord-035067-ic843wr9 9 24 August August NNP cord-035067-ic843wr9 9 25 . . . cord-035067-ic843wr9 10 1 It -PRON- PRP cord-035067-ic843wr9 10 2 is be VBZ cord-035067-ic843wr9 10 3 caused cause VBN cord-035067-ic843wr9 10 4 by by IN cord-035067-ic843wr9 10 5 SARS SARS NNP cord-035067-ic843wr9 10 6 - - HYPH cord-035067-ic843wr9 10 7 CoV-2 CoV-2 NNP cord-035067-ic843wr9 10 8 and and CC cord-035067-ic843wr9 10 9 the the DT cord-035067-ic843wr9 10 10 transmission transmission NN cord-035067-ic843wr9 10 11 is be VBZ cord-035067-ic843wr9 10 12 through through IN cord-035067-ic843wr9 10 13 the the DT cord-035067-ic843wr9 10 14 respiratory respiratory JJ cord-035067-ic843wr9 10 15 tract tract NN cord-035067-ic843wr9 10 16 . . . cord-035067-ic843wr9 11 1 Those those DT cord-035067-ic843wr9 11 2 infected infected JJ cord-035067-ic843wr9 11 3 may may MD cord-035067-ic843wr9 11 4 be be VB cord-035067-ic843wr9 11 5 asymptomatic asymptomatic JJ cord-035067-ic843wr9 11 6 , , , cord-035067-ic843wr9 11 7 present present JJ cord-035067-ic843wr9 11 8 typical typical JJ cord-035067-ic843wr9 11 9 symptoms symptom NNS cord-035067-ic843wr9 11 10 ( ( -LRB- cord-035067-ic843wr9 11 11 fever fever NN cord-035067-ic843wr9 11 12 , , , cord-035067-ic843wr9 11 13 dry dry JJ cord-035067-ic843wr9 11 14 cough cough NN cord-035067-ic843wr9 11 15 and and CC cord-035067-ic843wr9 11 16 dyspnea dyspnea NN cord-035067-ic843wr9 11 17 ) ) -RRB- cord-035067-ic843wr9 11 18 , , , cord-035067-ic843wr9 11 19 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 11 20 symptoms symptom NNS cord-035067-ic843wr9 11 21 ( ( -LRB- cord-035067-ic843wr9 11 22 diarrhea diarrhea NN cord-035067-ic843wr9 11 23 , , , cord-035067-ic843wr9 11 24 nausea nausea NN cord-035067-ic843wr9 11 25 , , , cord-035067-ic843wr9 11 26 vomiting vomiting NN cord-035067-ic843wr9 11 27 and and CC cord-035067-ic843wr9 11 28 abdominal abdominal JJ cord-035067-ic843wr9 11 29 pain pain NN cord-035067-ic843wr9 11 30 ) ) -RRB- cord-035067-ic843wr9 11 31 and and CC cord-035067-ic843wr9 11 32 viral viral JJ cord-035067-ic843wr9 11 33 RNA RNA NNP cord-035067-ic843wr9 11 34 in in IN cord-035067-ic843wr9 11 35 stools stool NNS cord-035067-ic843wr9 11 36 . . . cord-035067-ic843wr9 12 1 The the DT cord-035067-ic843wr9 12 2 objective objective NN cord-035067-ic843wr9 12 3 of of IN cord-035067-ic843wr9 12 4 this this DT cord-035067-ic843wr9 12 5 work work NN cord-035067-ic843wr9 12 6 was be VBD cord-035067-ic843wr9 12 7 to to TO cord-035067-ic843wr9 12 8 review review VB cord-035067-ic843wr9 12 9 the the DT cord-035067-ic843wr9 12 10 literature literature NN cord-035067-ic843wr9 12 11 related relate VBN cord-035067-ic843wr9 12 12 to to IN cord-035067-ic843wr9 12 13 the the DT cord-035067-ic843wr9 12 14 prevalence prevalence NN cord-035067-ic843wr9 12 15 of of IN cord-035067-ic843wr9 12 16 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 12 17 symptoms symptom NNS cord-035067-ic843wr9 12 18 , , , cord-035067-ic843wr9 12 19 and and CC cord-035067-ic843wr9 12 20 to to TO cord-035067-ic843wr9 12 21 check check VB cord-035067-ic843wr9 12 22 the the DT cord-035067-ic843wr9 12 23 possibility possibility NN cord-035067-ic843wr9 12 24 of of IN cord-035067-ic843wr9 12 25 fecal fecal JJ cord-035067-ic843wr9 12 26 - - HYPH cord-035067-ic843wr9 12 27 oral oral JJ cord-035067-ic843wr9 12 28 transmission transmission NN cord-035067-ic843wr9 12 29 . . . cord-035067-ic843wr9 13 1 We -PRON- PRP cord-035067-ic843wr9 13 2 searched search VBD cord-035067-ic843wr9 13 3 PubMed PubMed NNP cord-035067-ic843wr9 13 4 ( ( -LRB- cord-035067-ic843wr9 13 5 ® ® NNP cord-035067-ic843wr9 13 6 ) ) -RRB- cord-035067-ic843wr9 13 7 database database NN cord-035067-ic843wr9 13 8 on on IN cord-035067-ic843wr9 13 9 COVID-19 covid-19 JJ cord-035067-ic843wr9 13 10 and and CC cord-035067-ic843wr9 13 11 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 13 12 tract tract NN cord-035067-ic843wr9 13 13 and and CC cord-035067-ic843wr9 13 14 selected select VBN cord-035067-ic843wr9 13 15 articles article NNS cord-035067-ic843wr9 13 16 using use VBG cord-035067-ic843wr9 13 17 the the DT cord-035067-ic843wr9 13 18 PRISMA PRISMA NNP cord-035067-ic843wr9 13 19 method method NN cord-035067-ic843wr9 13 20 . . . cord-035067-ic843wr9 14 1 We -PRON- PRP cord-035067-ic843wr9 14 2 eliminated eliminate VBD cord-035067-ic843wr9 14 3 articles article NNS cord-035067-ic843wr9 14 4 based base VBN cord-035067-ic843wr9 14 5 on on IN cord-035067-ic843wr9 14 6 titles title NNS cord-035067-ic843wr9 14 7 and and CC cord-035067-ic843wr9 14 8 abstracts abstract NNS cord-035067-ic843wr9 14 9 , , , cord-035067-ic843wr9 14 10 small small JJ cord-035067-ic843wr9 14 11 number number NN cord-035067-ic843wr9 14 12 of of IN cord-035067-ic843wr9 14 13 patients patient NNS cord-035067-ic843wr9 14 14 and and CC cord-035067-ic843wr9 14 15 the the DT cord-035067-ic843wr9 14 16 mechanism mechanism NN cord-035067-ic843wr9 14 17 of of IN cord-035067-ic843wr9 14 18 infection infection NN cord-035067-ic843wr9 14 19 , , , cord-035067-ic843wr9 14 20 leaving leave VBG cord-035067-ic843wr9 14 21 14 14 CD cord-035067-ic843wr9 14 22 studies study NNS cord-035067-ic843wr9 14 23 . . . cord-035067-ic843wr9 15 1 Comorbidities comorbiditie NNS cord-035067-ic843wr9 15 2 and and CC cord-035067-ic843wr9 15 3 laboratory laboratory NN cord-035067-ic843wr9 15 4 alterations alteration NNS cord-035067-ic843wr9 15 5 ( ( -LRB- cord-035067-ic843wr9 15 6 elevation elevation NN cord-035067-ic843wr9 15 7 of of IN cord-035067-ic843wr9 15 8 hepatic hepatic JJ cord-035067-ic843wr9 15 9 aminotransferases aminotransferase NNS cord-035067-ic843wr9 15 10 and and CC cord-035067-ic843wr9 15 11 bilirubin bilirubin NN cord-035067-ic843wr9 15 12 ) ) -RRB- cord-035067-ic843wr9 15 13 were be VBD cord-035067-ic843wr9 15 14 related relate VBN cord-035067-ic843wr9 15 15 to to IN cord-035067-ic843wr9 15 16 worsening worsen VBG cord-035067-ic843wr9 15 17 of of IN cord-035067-ic843wr9 15 18 the the DT cord-035067-ic843wr9 15 19 disease disease NN cord-035067-ic843wr9 15 20 . . . cord-035067-ic843wr9 16 1 The the DT cord-035067-ic843wr9 16 2 prevalence prevalence NN cord-035067-ic843wr9 16 3 of of IN cord-035067-ic843wr9 16 4 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 16 5 symptoms symptom NNS cord-035067-ic843wr9 16 6 ranged range VBD cord-035067-ic843wr9 16 7 from from IN cord-035067-ic843wr9 16 8 6.8 6.8 CD cord-035067-ic843wr9 16 9 % % NN cord-035067-ic843wr9 16 10 to to IN cord-035067-ic843wr9 16 11 61.3 61.3 CD cord-035067-ic843wr9 16 12 % % NN cord-035067-ic843wr9 16 13 , , , cord-035067-ic843wr9 16 14 including include VBG cord-035067-ic843wr9 16 15 diarrhea diarrhea NN cord-035067-ic843wr9 16 16 ( ( -LRB- cord-035067-ic843wr9 16 17 8.14 8.14 CD cord-035067-ic843wr9 16 18 % % NN cord-035067-ic843wr9 16 19 to to IN cord-035067-ic843wr9 16 20 33.7 33.7 CD cord-035067-ic843wr9 16 21 % % NN cord-035067-ic843wr9 16 22 ) ) -RRB- cord-035067-ic843wr9 16 23 , , , cord-035067-ic843wr9 16 24 nausea nausea NN cord-035067-ic843wr9 16 25 / / SYM cord-035067-ic843wr9 16 26 vomiting vomiting NN cord-035067-ic843wr9 16 27 ( ( -LRB- cord-035067-ic843wr9 16 28 1.53 1.53 CD cord-035067-ic843wr9 16 29 % % NN cord-035067-ic843wr9 16 30 to to IN cord-035067-ic843wr9 16 31 26.4 26.4 CD cord-035067-ic843wr9 16 32 % % NN cord-035067-ic843wr9 16 33 ) ) -RRB- cord-035067-ic843wr9 16 34 , , , cord-035067-ic843wr9 16 35 anorexia anorexia NN cord-035067-ic843wr9 16 36 ( ( -LRB- cord-035067-ic843wr9 16 37 12.1 12.1 CD cord-035067-ic843wr9 16 38 % % NN cord-035067-ic843wr9 16 39 to to IN cord-035067-ic843wr9 16 40 40.0 40.0 CD cord-035067-ic843wr9 16 41 % % NN cord-035067-ic843wr9 16 42 ) ) -RRB- cord-035067-ic843wr9 16 43 and and CC cord-035067-ic843wr9 16 44 abdominal abdominal JJ cord-035067-ic843wr9 16 45 pain pain NN cord-035067-ic843wr9 16 46 ( ( -LRB- cord-035067-ic843wr9 16 47 0 0 CD cord-035067-ic843wr9 16 48 % % NN cord-035067-ic843wr9 16 49 to to TO cord-035067-ic843wr9 16 50 14.5 14.5 CD cord-035067-ic843wr9 16 51 % % NN cord-035067-ic843wr9 16 52 ) ) -RRB- cord-035067-ic843wr9 16 53 . . . cord-035067-ic843wr9 17 1 The the DT cord-035067-ic843wr9 17 2 presence presence NN cord-035067-ic843wr9 17 3 of of IN cord-035067-ic843wr9 17 4 viral viral JJ cord-035067-ic843wr9 17 5 RNA RNA NNP cord-035067-ic843wr9 17 6 in in IN cord-035067-ic843wr9 17 7 stools stool NNS cord-035067-ic843wr9 17 8 was be VBD cord-035067-ic843wr9 17 9 rarely rarely RB cord-035067-ic843wr9 17 10 tested test VBN cord-035067-ic843wr9 17 11 , , , cord-035067-ic843wr9 17 12 but but CC cord-035067-ic843wr9 17 13 positive positive JJ cord-035067-ic843wr9 17 14 in in IN cord-035067-ic843wr9 17 15 0 0 CD cord-035067-ic843wr9 17 16 % % NN cord-035067-ic843wr9 17 17 to to IN cord-035067-ic843wr9 17 18 48.1 48.1 CD cord-035067-ic843wr9 17 19 % % NN cord-035067-ic843wr9 17 20 . . . cord-035067-ic843wr9 18 1 The the DT cord-035067-ic843wr9 18 2 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 18 3 tract tract NN cord-035067-ic843wr9 18 4 is be VBZ cord-035067-ic843wr9 18 5 affected affect VBN cord-035067-ic843wr9 18 6 by by IN cord-035067-ic843wr9 18 7 COVID-19 COVID-19 NNP cord-035067-ic843wr9 18 8 , , , cord-035067-ic843wr9 18 9 causing cause VBG cord-035067-ic843wr9 18 10 specific specific JJ cord-035067-ic843wr9 18 11 symptoms symptom NNS cord-035067-ic843wr9 18 12 , , , cord-035067-ic843wr9 18 13 laboratory laboratory NN cord-035067-ic843wr9 18 14 alterations alteration NNS cord-035067-ic843wr9 18 15 and and CC cord-035067-ic843wr9 18 16 viral viral JJ cord-035067-ic843wr9 18 17 presence presence NN cord-035067-ic843wr9 18 18 in in IN cord-035067-ic843wr9 18 19 the the DT cord-035067-ic843wr9 18 20 feces fece NNS cord-035067-ic843wr9 18 21 . . . cord-035067-ic843wr9 19 1 However however RB cord-035067-ic843wr9 19 2 , , , cord-035067-ic843wr9 19 3 the the DT cord-035067-ic843wr9 19 4 results result NNS cord-035067-ic843wr9 19 5 of of IN cord-035067-ic843wr9 19 6 prevalence prevalence NN cord-035067-ic843wr9 19 7 and and CC cord-035067-ic843wr9 19 8 possibility possibility NN cord-035067-ic843wr9 19 9 of of IN cord-035067-ic843wr9 19 10 fecal fecal JJ cord-035067-ic843wr9 19 11 - - HYPH cord-035067-ic843wr9 19 12 oral oral JJ cord-035067-ic843wr9 19 13 transmission transmission NN cord-035067-ic843wr9 19 14 were be VBD cord-035067-ic843wr9 19 15 varied varied JJ cord-035067-ic843wr9 19 16 , , , cord-035067-ic843wr9 19 17 requiring require VBG cord-035067-ic843wr9 19 18 further further JJ cord-035067-ic843wr9 19 19 studies study NNS cord-035067-ic843wr9 19 20 for for IN cord-035067-ic843wr9 19 21 more more RBR cord-035067-ic843wr9 19 22 assertive assertive JJ cord-035067-ic843wr9 19 23 conclusions conclusion NNS cord-035067-ic843wr9 19 24 . . . cord-035067-ic843wr9 20 1 It -PRON- PRP cord-035067-ic843wr9 20 2 is be VBZ cord-035067-ic843wr9 20 3 important important JJ cord-035067-ic843wr9 20 4 that that IN cord-035067-ic843wr9 20 5 healthcare healthcare NN cord-035067-ic843wr9 20 6 professionals professional NNS cord-035067-ic843wr9 20 7 draw draw VBP cord-035067-ic843wr9 20 8 attention attention NN cord-035067-ic843wr9 20 9 to to IN cord-035067-ic843wr9 20 10 this this DT cord-035067-ic843wr9 20 11 fact fact NN cord-035067-ic843wr9 20 12 , , , cord-035067-ic843wr9 20 13 since since IN cord-035067-ic843wr9 20 14 these these DT cord-035067-ic843wr9 20 15 changes change NNS cord-035067-ic843wr9 20 16 can can MD cord-035067-ic843wr9 20 17 help help VB cord-035067-ic843wr9 20 18 make make VB cord-035067-ic843wr9 20 19 diagnosis diagnosis NN cord-035067-ic843wr9 20 20 and and CC cord-035067-ic843wr9 20 21 initiate initiate VB cord-035067-ic843wr9 20 22 early early JJ cord-035067-ic843wr9 20 23 treatment treatment NN cord-035067-ic843wr9 20 24 . . . cord-035067-ic843wr9 21 1 Com Com NNP cord-035067-ic843wr9 21 2 quase quase NNP cord-035067-ic843wr9 21 3 17,5 17,5 CD cord-035067-ic843wr9 21 4 milhões milhões NNP cord-035067-ic843wr9 21 5 de de NNP cord-035067-ic843wr9 21 6 infectados infectados NNP cord-035067-ic843wr9 21 7 e e NNP cord-035067-ic843wr9 21 8 700 700 CD cord-035067-ic843wr9 21 9 mil mil NN cord-035067-ic843wr9 21 10 mortos mortos NN cord-035067-ic843wr9 21 11 até até NNP cord-035067-ic843wr9 21 12 o o NN cord-035067-ic843wr9 21 13 início início NNP cord-035067-ic843wr9 21 14 de de FW cord-035067-ic843wr9 21 15 agosto agosto NNP cord-035067-ic843wr9 21 16 no no DT cord-035067-ic843wr9 21 17 mundo mundo XX cord-035067-ic843wr9 22 1 , , , cord-035067-ic843wr9 22 2 a a DT cord-035067-ic843wr9 22 3 pandemia pandemia NN cord-035067-ic843wr9 22 4 do do VBP cord-035067-ic843wr9 22 5 novo novo VB cord-035067-ic843wr9 22 6 coronavírus coronavírus NNP cord-035067-ic843wr9 22 7 está está NNP cord-035067-ic843wr9 22 8 marcando marcando NNP cord-035067-ic843wr9 22 9 o o NN cord-035067-ic843wr9 22 10 ano ano NNP cord-035067-ic843wr9 22 11 de de IN cord-035067-ic843wr9 22 12 2020 2020 CD cord-035067-ic843wr9 22 13 . . . cord-035067-ic843wr9 23 1 O o UH cord-035067-ic843wr9 23 2 agente agente FW cord-035067-ic843wr9 23 3 causador causador NNP cord-035067-ic843wr9 24 1 da da NNP cord-035067-ic843wr9 24 2 doença doença NNP cord-035067-ic843wr9 24 3 é é NNP cord-035067-ic843wr9 24 4 o o NN cord-035067-ic843wr9 24 5 vírus vírus FW cord-035067-ic843wr9 24 6 SARS SARS NNP cord-035067-ic843wr9 24 7 - - HYPH cord-035067-ic843wr9 24 8 CoV-2 CoV-2 NNP cord-035067-ic843wr9 24 9 , , , cord-035067-ic843wr9 24 10 e e LS cord-035067-ic843wr9 24 11 a a DT cord-035067-ic843wr9 24 12 transmissão transmissão NNP cord-035067-ic843wr9 24 13 é é FW cord-035067-ic843wr9 24 14 por por FW cord-035067-ic843wr9 24 15 via via IN cord-035067-ic843wr9 24 16 respiratória respiratória NNP cord-035067-ic843wr9 24 17 . . . cord-035067-ic843wr9 25 1 Os Os NNP cord-035067-ic843wr9 25 2 infectados infectados NNP cord-035067-ic843wr9 25 3 podem podem FW cord-035067-ic843wr9 25 4 ser ser NNP cord-035067-ic843wr9 25 5 assintomáticos assintomáticos NNP cord-035067-ic843wr9 25 6 , , , cord-035067-ic843wr9 25 7 apresentar apresentar NNP cord-035067-ic843wr9 25 8 sintomas sintomas NNP cord-035067-ic843wr9 25 9 típicos típicos NNP cord-035067-ic843wr9 25 10 ( ( -LRB- cord-035067-ic843wr9 25 11 febre febre NNP cord-035067-ic843wr9 25 12 , , , cord-035067-ic843wr9 25 13 tosse tosse NNP cord-035067-ic843wr9 25 14 seca seca NNP cord-035067-ic843wr9 25 15 e e NNP cord-035067-ic843wr9 25 16 dispneia dispneia NNP cord-035067-ic843wr9 25 17 ) ) -RRB- cord-035067-ic843wr9 25 18 , , , cord-035067-ic843wr9 25 19 sintomas sintomas NNP cord-035067-ic843wr9 25 20 gastrintestinais gastrintestinais NNP cord-035067-ic843wr9 25 21 ( ( -LRB- cord-035067-ic843wr9 25 22 diarreia diarreia NNP cord-035067-ic843wr9 25 23 , , , cord-035067-ic843wr9 25 24 náusea náusea NNP cord-035067-ic843wr9 25 25 , , , cord-035067-ic843wr9 25 26 vômito vômito NNP cord-035067-ic843wr9 25 27 e e DT cord-035067-ic843wr9 25 28 dor dor NNP cord-035067-ic843wr9 25 29 abdominal abdominal NNP cord-035067-ic843wr9 25 30 ) ) -RRB- cord-035067-ic843wr9 26 1 e e LS cord-035067-ic843wr9 26 2 RNA RNA NNP cord-035067-ic843wr9 26 3 viral viral JJ cord-035067-ic843wr9 26 4 nas nas NNP cord-035067-ic843wr9 26 5 fezes fezes NNP cord-035067-ic843wr9 26 6 . . . cord-035067-ic843wr9 27 1 O o UH cord-035067-ic843wr9 27 2 objetivo objetivo NNP cord-035067-ic843wr9 27 3 deste deste NNP cord-035067-ic843wr9 27 4 trabalho trabalho NNP cord-035067-ic843wr9 27 5 foi foi NNP cord-035067-ic843wr9 27 6 revisar revisar NNP cord-035067-ic843wr9 27 7 a a DT cord-035067-ic843wr9 27 8 literatura literatura NNP cord-035067-ic843wr9 27 9 relacionada relacionada NNP cord-035067-ic843wr9 27 10 com com NNP cord-035067-ic843wr9 27 11 a a DT cord-035067-ic843wr9 27 12 prevalência prevalência NN cord-035067-ic843wr9 27 13 dos do VBZ cord-035067-ic843wr9 27 14 sintomas sintomas NNP cord-035067-ic843wr9 27 15 gastrintestinais gastrintestinais NNP cord-035067-ic843wr9 27 16 , , , cord-035067-ic843wr9 27 17 e e LS cord-035067-ic843wr9 27 18 verificar verificar FW cord-035067-ic843wr9 27 19 se se FW cord-035067-ic843wr9 27 20 é é NN cord-035067-ic843wr9 28 1 possível possível NNP cord-035067-ic843wr9 28 2 a a DT cord-035067-ic843wr9 28 3 transmissão transmissão JJ cord-035067-ic843wr9 28 4 fecal fecal JJ cord-035067-ic843wr9 28 5 - - HYPH cord-035067-ic843wr9 28 6 oral oral JJ cord-035067-ic843wr9 28 7 da da NN cord-035067-ic843wr9 28 8 doença doença NN cord-035067-ic843wr9 28 9 . . . cord-035067-ic843wr9 29 1 Fizemos Fizemos NNP cord-035067-ic843wr9 29 2 uma uma NNP cord-035067-ic843wr9 29 3 pesquisa pesquisa NNP cord-035067-ic843wr9 29 4 na na NNP cord-035067-ic843wr9 29 5 base base NNP cord-035067-ic843wr9 29 6 de de FW cord-035067-ic843wr9 29 7 dados dados NNP cord-035067-ic843wr9 29 8 PubMed PubMed NNP cord-035067-ic843wr9 30 1 ® ® . cord-035067-ic843wr9 31 1 sobre sobre NNP cord-035067-ic843wr9 31 2 a a NNP cord-035067-ic843wr9 31 3 COVID-19 COVID-19 NNP cord-035067-ic843wr9 31 4 e e NNP cord-035067-ic843wr9 31 5 o o FW cord-035067-ic843wr9 31 6 trato trato NNP cord-035067-ic843wr9 31 7 gastrintestinal gastrintestinal NNP cord-035067-ic843wr9 31 8 , , , cord-035067-ic843wr9 31 9 selecionando selecionando NNP cord-035067-ic843wr9 31 10 artigos artigos NNP cord-035067-ic843wr9 31 11 pelo pelo NNP cord-035067-ic843wr9 31 12 método método NNP cord-035067-ic843wr9 31 13 PRISMA PRISMA NNP cord-035067-ic843wr9 31 14 . . . cord-035067-ic843wr9 32 1 Eliminamos Eliminamos NNP cord-035067-ic843wr9 32 2 artigos artigos NN cord-035067-ic843wr9 32 3 com com NN cord-035067-ic843wr9 32 4 base base NN cord-035067-ic843wr9 32 5 em -PRON- PRP cord-035067-ic843wr9 32 6 títulos títulos NNP cord-035067-ic843wr9 32 7 e e NNP cord-035067-ic843wr9 32 8 resumos resumos NNP cord-035067-ic843wr9 32 9 , , , cord-035067-ic843wr9 32 10 quantidade quantidade NNP cord-035067-ic843wr9 32 11 pequena pequena NNP cord-035067-ic843wr9 32 12 de de FW cord-035067-ic843wr9 32 13 pacientes pacientes NNP cord-035067-ic843wr9 32 14 e e NNP cord-035067-ic843wr9 32 15 sobre sobre NNP cord-035067-ic843wr9 32 16 mecanismo mecanismo NNP cord-035067-ic843wr9 32 17 de de NNP cord-035067-ic843wr9 32 18 infecção infecção NNP cord-035067-ic843wr9 32 19 , , , cord-035067-ic843wr9 32 20 restando restando NNP cord-035067-ic843wr9 32 21 14 14 CD cord-035067-ic843wr9 32 22 estudos estudo NNS cord-035067-ic843wr9 32 23 . . . cord-035067-ic843wr9 33 1 Comorbidades Comorbidades NNP cord-035067-ic843wr9 33 2 e e NNP cord-035067-ic843wr9 33 3 alterações alterações NNP cord-035067-ic843wr9 33 4 laboratoriais laboratoriais NNP cord-035067-ic843wr9 34 1 ( ( -LRB- cord-035067-ic843wr9 34 2 elevação elevação NNP cord-035067-ic843wr9 34 3 de de NNP cord-035067-ic843wr9 34 4 aminotransferases aminotransferases NNP cord-035067-ic843wr9 34 5 hepáticas hepáticas NNP cord-035067-ic843wr9 34 6 e e NNP cord-035067-ic843wr9 34 7 bilirrubina bilirrubina NNP cord-035067-ic843wr9 34 8 ) ) -RRB- cord-035067-ic843wr9 35 1 foram foram NNP cord-035067-ic843wr9 35 2 relacionadas relacionadas NNP cord-035067-ic843wr9 35 3 com com NN cord-035067-ic843wr9 35 4 piora piora NNP cord-035067-ic843wr9 35 5 da da NNP cord-035067-ic843wr9 35 6 doença doença NNP cord-035067-ic843wr9 35 7 . . . cord-035067-ic843wr9 36 1 A a DT cord-035067-ic843wr9 36 2 prevalência prevalência NN cord-035067-ic843wr9 36 3 de de IN cord-035067-ic843wr9 36 4 sintomas sintomas NNP cord-035067-ic843wr9 36 5 gastrintestinais gastrintestinais NNP cord-035067-ic843wr9 36 6 variou variou NNP cord-035067-ic843wr9 36 7 entre entre NNP cord-035067-ic843wr9 36 8 6,8 6,8 CD cord-035067-ic843wr9 36 9 % % NN cord-035067-ic843wr9 36 10 e e NN cord-035067-ic843wr9 36 11 61,3 61,3 CD cord-035067-ic843wr9 36 12 % % NN cord-035067-ic843wr9 36 13 , , , cord-035067-ic843wr9 36 14 sendo sendo NNP cord-035067-ic843wr9 36 15 eles eles NNP cord-035067-ic843wr9 36 16 diarreia diarreia NNP cord-035067-ic843wr9 36 17 ( ( -LRB- cord-035067-ic843wr9 36 18 8,14 8,14 CD cord-035067-ic843wr9 36 19 % % NN cord-035067-ic843wr9 36 20 a a DT cord-035067-ic843wr9 36 21 33,7 33,7 CD cord-035067-ic843wr9 36 22 % % NN cord-035067-ic843wr9 36 23 ) ) -RRB- cord-035067-ic843wr9 36 24 , , , cord-035067-ic843wr9 36 25 náusea náusea NNP cord-035067-ic843wr9 36 26 / / SYM cord-035067-ic843wr9 36 27 vômito vômito NNP cord-035067-ic843wr9 36 28 ( ( -LRB- cord-035067-ic843wr9 36 29 1,53 1,53 CD cord-035067-ic843wr9 36 30 % % NN cord-035067-ic843wr9 36 31 a a DT cord-035067-ic843wr9 36 32 26,4 26,4 CD cord-035067-ic843wr9 36 33 % % NN cord-035067-ic843wr9 36 34 ) ) -RRB- cord-035067-ic843wr9 36 35 , , , cord-035067-ic843wr9 36 36 anorexia anorexia NN cord-035067-ic843wr9 36 37 ( ( -LRB- cord-035067-ic843wr9 36 38 12,1 12,1 CD cord-035067-ic843wr9 36 39 % % NN cord-035067-ic843wr9 36 40 a a DT cord-035067-ic843wr9 36 41 40,0 40,0 CD cord-035067-ic843wr9 36 42 % % NN cord-035067-ic843wr9 36 43 ) ) -RRB- cord-035067-ic843wr9 36 44 e e NFP cord-035067-ic843wr9 36 45 dor dor NNP cord-035067-ic843wr9 36 46 abdominal abdominal NN cord-035067-ic843wr9 36 47 ( ( -LRB- cord-035067-ic843wr9 36 48 0 0 CD cord-035067-ic843wr9 36 49 % % NN cord-035067-ic843wr9 36 50 a a DT cord-035067-ic843wr9 36 51 14,5 14,5 CD cord-035067-ic843wr9 36 52 % % NN cord-035067-ic843wr9 36 53 ) ) -RRB- cord-035067-ic843wr9 36 54 . . . cord-035067-ic843wr9 37 1 A a DT cord-035067-ic843wr9 37 2 presença presença NNP cord-035067-ic843wr9 37 3 do do VBP cord-035067-ic843wr9 37 4 RNA RNA NNP cord-035067-ic843wr9 37 5 viral viral JJ cord-035067-ic843wr9 37 6 foi foi FW cord-035067-ic843wr9 37 7 pouco pouco FW cord-035067-ic843wr9 37 8 testada testada NN cord-035067-ic843wr9 37 9 , , , cord-035067-ic843wr9 38 1 mas mas NNP cord-035067-ic843wr9 38 2 foi foi NNP cord-035067-ic843wr9 39 1 positiva positiva NNP cord-035067-ic843wr9 39 2 entre entre NNP cord-035067-ic843wr9 39 3 0 0 CD cord-035067-ic843wr9 39 4 % % NN cord-035067-ic843wr9 39 5 a a DT cord-035067-ic843wr9 39 6 48,1 48,1 CD cord-035067-ic843wr9 39 7 % % NN cord-035067-ic843wr9 39 8 . . . cord-035067-ic843wr9 40 1 O o UH cord-035067-ic843wr9 41 1 trato trato NNP cord-035067-ic843wr9 41 2 gastrintestinal gastrintestinal NNP cord-035067-ic843wr9 41 3 é é NNP cord-035067-ic843wr9 41 4 muito muito NNP cord-035067-ic843wr9 41 5 acometido acometido NNP cord-035067-ic843wr9 41 6 pela pela NNP cord-035067-ic843wr9 42 1 COVID-19 COVID-19 NNP cord-035067-ic843wr9 42 2 , , , cord-035067-ic843wr9 42 3 provocando provocando NNP cord-035067-ic843wr9 42 4 sintomas sintomas NNP cord-035067-ic843wr9 42 5 específicos específicos NNP cord-035067-ic843wr9 42 6 , , , cord-035067-ic843wr9 42 7 alterações alterações NNP cord-035067-ic843wr9 42 8 laboratoriais laboratoriais NNP cord-035067-ic843wr9 42 9 e e NNP cord-035067-ic843wr9 42 10 presença presença NNP cord-035067-ic843wr9 42 11 viral viral JJ cord-035067-ic843wr9 42 12 nas nas NNP cord-035067-ic843wr9 42 13 fezes fezes NNP cord-035067-ic843wr9 42 14 . . . cord-035067-ic843wr9 43 1 Contudo Contudo NNP cord-035067-ic843wr9 43 2 , , , cord-035067-ic843wr9 43 3 os os NNP cord-035067-ic843wr9 43 4 resultados resultados NNP cord-035067-ic843wr9 43 5 de de NNP cord-035067-ic843wr9 43 6 prevalência prevalência NNP cord-035067-ic843wr9 43 7 e e NNP cord-035067-ic843wr9 43 8 a a DT cord-035067-ic843wr9 43 9 possibilidade possibilidade NNP cord-035067-ic843wr9 43 10 de de FW cord-035067-ic843wr9 43 11 transmissão transmissão NNP cord-035067-ic843wr9 43 12 fecal fecal JJ cord-035067-ic843wr9 43 13 - - HYPH cord-035067-ic843wr9 43 14 oral oral JJ cord-035067-ic843wr9 43 15 foram foram NNS cord-035067-ic843wr9 43 16 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 43 17 involvement involvement NN cord-035067-ic843wr9 43 18 , , , cord-035067-ic843wr9 43 19 which which WDT cord-035067-ic843wr9 43 20 also also RB cord-035067-ic843wr9 43 21 has have VBZ cord-035067-ic843wr9 43 22 ACE2 ACE2 NNP cord-035067-ic843wr9 43 23 receptors receptor NNS cord-035067-ic843wr9 43 24 at at IN cord-035067-ic843wr9 43 25 the the DT cord-035067-ic843wr9 43 26 brush brush NN cord-035067-ic843wr9 43 27 border border NN cord-035067-ic843wr9 43 28 of of IN cord-035067-ic843wr9 43 29 the the DT cord-035067-ic843wr9 43 30 intestinal intestinal JJ cord-035067-ic843wr9 43 31 mucosa mucosa NN cord-035067-ic843wr9 43 32 . . . cord-035067-ic843wr9 44 1 ( ( -LRB- cord-035067-ic843wr9 44 2 6 6 CD cord-035067-ic843wr9 44 3 ) ) -RRB- cord-035067-ic843wr9 45 1 In in IN cord-035067-ic843wr9 45 2 addition addition NN cord-035067-ic843wr9 45 3 , , , cord-035067-ic843wr9 45 4 the the DT cord-035067-ic843wr9 45 5 virus virus NN cord-035067-ic843wr9 45 6 is be VBZ cord-035067-ic843wr9 45 7 released release VBN cord-035067-ic843wr9 45 8 at at IN cord-035067-ic843wr9 45 9 the the DT cord-035067-ic843wr9 45 10 apical apical JJ cord-035067-ic843wr9 45 11 part part NN cord-035067-ic843wr9 45 12 of of IN cord-035067-ic843wr9 45 13 the the DT cord-035067-ic843wr9 45 14 lung lung NN cord-035067-ic843wr9 45 15 cells cell NNS cord-035067-ic843wr9 45 16 . . . cord-035067-ic843wr9 46 1 Dragged drag VBN cord-035067-ic843wr9 46 2 by by IN cord-035067-ic843wr9 46 3 mucociliary mucociliary JJ cord-035067-ic843wr9 46 4 movement movement NN cord-035067-ic843wr9 46 5 , , , cord-035067-ic843wr9 46 6 it -PRON- PRP cord-035067-ic843wr9 46 7 can can MD cord-035067-ic843wr9 46 8 gain gain VB cord-035067-ic843wr9 46 9 the the DT cord-035067-ic843wr9 46 10 GIT git NN cord-035067-ic843wr9 46 11 . . . cord-035067-ic843wr9 47 1 These these DT cord-035067-ic843wr9 47 2 ACE2 ACE2 NNP cord-035067-ic843wr9 47 3 receptors receptor NNS cord-035067-ic843wr9 47 4 operate operate VBP cord-035067-ic843wr9 47 5 diminishing diminish VBG cord-035067-ic843wr9 47 6 the the DT cord-035067-ic843wr9 47 7 action action NN cord-035067-ic843wr9 47 8 of of IN cord-035067-ic843wr9 47 9 the the DT cord-035067-ic843wr9 47 10 renin renin NN cord-035067-ic843wr9 47 11 - - HYPH cord-035067-ic843wr9 47 12 angiotensinaldosterone angiotensinaldosterone NN cord-035067-ic843wr9 47 13 system system NN cord-035067-ic843wr9 47 14 by by IN cord-035067-ic843wr9 47 15 metabolizing metabolize VBG cord-035067-ic843wr9 47 16 angiotensin angiotensin NN cord-035067-ic843wr9 47 17 2 2 CD cord-035067-ic843wr9 47 18 . . . cord-035067-ic843wr9 48 1 At at IN cord-035067-ic843wr9 48 2 high high JJ cord-035067-ic843wr9 48 3 serum serum NN cord-035067-ic843wr9 48 4 levels level NNS cord-035067-ic843wr9 48 5 , , , cord-035067-ic843wr9 48 6 angiotensin angiotensin NN cord-035067-ic843wr9 48 7 2 2 CD cord-035067-ic843wr9 48 8 has have VBZ cord-035067-ic843wr9 48 9 effects effect NNS cord-035067-ic843wr9 48 10 on on IN cord-035067-ic843wr9 48 11 cardiovascular cardiovascular JJ cord-035067-ic843wr9 48 12 , , , cord-035067-ic843wr9 48 13 renal renal JJ cord-035067-ic843wr9 48 14 , , , cord-035067-ic843wr9 48 15 and and CC cord-035067-ic843wr9 48 16 respiratory respiratory JJ cord-035067-ic843wr9 48 17 systems system NNS cord-035067-ic843wr9 48 18 , , , cord-035067-ic843wr9 48 19 and and CC cord-035067-ic843wr9 48 20 may may MD cord-035067-ic843wr9 48 21 cause cause VB cord-035067-ic843wr9 48 22 chronic chronic JJ cord-035067-ic843wr9 48 23 hypertension hypertension NN cord-035067-ic843wr9 48 24 and and CC cord-035067-ic843wr9 48 25 renal renal JJ cord-035067-ic843wr9 48 26 and and CC cord-035067-ic843wr9 48 27 respiratory respiratory JJ cord-035067-ic843wr9 48 28 failure failure NN cord-035067-ic843wr9 48 29 . . . cord-035067-ic843wr9 49 1 The the DT cord-035067-ic843wr9 49 2 SARS SARS NNP cord-035067-ic843wr9 49 3 - - HYPH cord-035067-ic843wr9 49 4 CoV-2 CoV-2 NNP cord-035067-ic843wr9 49 5 virus virus NN cord-035067-ic843wr9 49 6 causes cause VBZ cord-035067-ic843wr9 49 7 downregulation downregulation NN cord-035067-ic843wr9 49 8 and and CC cord-035067-ic843wr9 49 9 blockage blockage NN cord-035067-ic843wr9 49 10 of of IN cord-035067-ic843wr9 49 11 these these DT cord-035067-ic843wr9 49 12 ACE2 ACE2 NNP cord-035067-ic843wr9 49 13 receptors receptor NNS cord-035067-ic843wr9 49 14 , , , cord-035067-ic843wr9 49 15 which which WDT cord-035067-ic843wr9 49 16 explains explain VBZ cord-035067-ic843wr9 49 17 the the DT cord-035067-ic843wr9 49 18 clinical clinical JJ cord-035067-ic843wr9 49 19 picture picture NN cord-035067-ic843wr9 49 20 of of IN cord-035067-ic843wr9 49 21 pulmonary pulmonary JJ cord-035067-ic843wr9 49 22 failure failure NN cord-035067-ic843wr9 49 23 and and CC cord-035067-ic843wr9 49 24 adult adult JJ cord-035067-ic843wr9 49 25 respiratory respiratory JJ cord-035067-ic843wr9 49 26 distress distress NN cord-035067-ic843wr9 49 27 syndrome syndrome NN cord-035067-ic843wr9 49 28 in in IN cord-035067-ic843wr9 49 29 some some DT cord-035067-ic843wr9 49 30 infected infected JJ cord-035067-ic843wr9 49 31 patients patient NNS cord-035067-ic843wr9 49 32 . . . cord-035067-ic843wr9 50 1 ( ( -LRB- cord-035067-ic843wr9 50 2 9 9 CD cord-035067-ic843wr9 50 3 ) ) -RRB- cord-035067-ic843wr9 51 1 The the DT cord-035067-ic843wr9 51 2 viral viral JJ cord-035067-ic843wr9 51 3 surface surface NN cord-035067-ic843wr9 51 4 has have VBZ cord-035067-ic843wr9 51 5 S s NN cord-035067-ic843wr9 51 6 ( ( -LRB- cord-035067-ic843wr9 51 7 Spike spike NN cord-035067-ic843wr9 51 8 ) ) -RRB- cord-035067-ic843wr9 51 9 glycoproteins glycoprotein NNS cord-035067-ic843wr9 51 10 , , , cord-035067-ic843wr9 51 11 which which WDT cord-035067-ic843wr9 51 12 need need VBP cord-035067-ic843wr9 51 13 to to TO cord-035067-ic843wr9 51 14 be be VB cord-035067-ic843wr9 51 15 separated separate VBN cord-035067-ic843wr9 51 16 into into IN cord-035067-ic843wr9 51 17 S1 S1 NNP cord-035067-ic843wr9 51 18 and and CC cord-035067-ic843wr9 51 19 S2 s2 NN cord-035067-ic843wr9 51 20 domains domain NNS cord-035067-ic843wr9 51 21 , , , cord-035067-ic843wr9 51 22 so so IN cord-035067-ic843wr9 51 23 that that IN cord-035067-ic843wr9 51 24 the the DT cord-035067-ic843wr9 51 25 virus virus NN cord-035067-ic843wr9 51 26 can can MD cord-035067-ic843wr9 51 27 adhere adhere VB cord-035067-ic843wr9 51 28 to to IN cord-035067-ic843wr9 51 29 the the DT cord-035067-ic843wr9 51 30 cell cell NN cord-035067-ic843wr9 51 31 membrane membrane NN cord-035067-ic843wr9 51 32 . . . cord-035067-ic843wr9 52 1 Furin furin NN cord-035067-ic843wr9 52 2 and and CC cord-035067-ic843wr9 52 3 transmembrane transmembrane NN cord-035067-ic843wr9 52 4 serine serine NN cord-035067-ic843wr9 52 5 protease protease NN cord-035067-ic843wr9 52 6 ( ( -LRB- cord-035067-ic843wr9 52 7 TMPRSS2 TMPRSS2 NNP cord-035067-ic843wr9 52 8 ) ) -RRB- cord-035067-ic843wr9 52 9 are be VBP cord-035067-ic843wr9 52 10 substances substance NNS cord-035067-ic843wr9 52 11 that that WDT cord-035067-ic843wr9 52 12 allow allow VBP cord-035067-ic843wr9 52 13 this this DT cord-035067-ic843wr9 52 14 separation separation NN cord-035067-ic843wr9 52 15 . . . cord-035067-ic843wr9 53 1 Thus thus RB cord-035067-ic843wr9 53 2 , , , cord-035067-ic843wr9 53 3 S1 s1 NN cord-035067-ic843wr9 53 4 binds bind VBZ cord-035067-ic843wr9 53 5 to to IN cord-035067-ic843wr9 53 6 the the DT cord-035067-ic843wr9 53 7 ACE2 ACE2 NNP cord-035067-ic843wr9 53 8 receptor receptor NN cord-035067-ic843wr9 53 9 and and CC cord-035067-ic843wr9 53 10 S2 s2 NN cord-035067-ic843wr9 53 11 to to IN cord-035067-ic843wr9 53 12 the the DT cord-035067-ic843wr9 53 13 cell cell NN cord-035067-ic843wr9 53 14 membrane membrane NN cord-035067-ic843wr9 53 15 , , , cord-035067-ic843wr9 53 16 allowing allow VBG cord-035067-ic843wr9 53 17 the the DT cord-035067-ic843wr9 53 18 virus virus NN cord-035067-ic843wr9 53 19 to to TO cord-035067-ic843wr9 53 20 enter enter VB cord-035067-ic843wr9 53 21 the the DT cord-035067-ic843wr9 53 22 cell cell NN cord-035067-ic843wr9 53 23 through through IN cord-035067-ic843wr9 53 24 endocytosis endocytosis NN cord-035067-ic843wr9 53 25 . . . cord-035067-ic843wr9 54 1 Furin Furin NNP cord-035067-ic843wr9 54 2 and and CC cord-035067-ic843wr9 54 3 TMPRSS2 TMPRSS2 NNP cord-035067-ic843wr9 54 4 are be VBP cord-035067-ic843wr9 54 5 enzymes enzyme NNS cord-035067-ic843wr9 54 6 present present JJ cord-035067-ic843wr9 54 7 in in IN cord-035067-ic843wr9 54 8 the the DT cord-035067-ic843wr9 54 9 cells cell NNS cord-035067-ic843wr9 54 10 of of IN cord-035067-ic843wr9 54 11 the the DT cord-035067-ic843wr9 54 12 small small JJ cord-035067-ic843wr9 54 13 intestine intestine NN cord-035067-ic843wr9 54 14 ; ; : cord-035067-ic843wr9 54 15 the the DT cord-035067-ic843wr9 54 16 former former JJ cord-035067-ic843wr9 54 17 also also RB cord-035067-ic843wr9 54 18 acts act VBZ cord-035067-ic843wr9 54 19 in in IN cord-035067-ic843wr9 54 20 the the DT cord-035067-ic843wr9 54 21 activation activation NN cord-035067-ic843wr9 54 22 of of IN cord-035067-ic843wr9 54 23 toxins toxin NNS cord-035067-ic843wr9 54 24 of of IN cord-035067-ic843wr9 54 25 some some DT cord-035067-ic843wr9 54 26 microorganisms microorganism NNS cord-035067-ic843wr9 54 27 . . . cord-035067-ic843wr9 55 1 ( ( -LRB- cord-035067-ic843wr9 55 2 7 7 CD cord-035067-ic843wr9 55 3 , , , cord-035067-ic843wr9 55 4 9 9 CD cord-035067-ic843wr9 55 5 ) ) -RRB- cord-035067-ic843wr9 55 6 ACE2 ACE2 NNP cord-035067-ic843wr9 55 7 of of IN cord-035067-ic843wr9 55 8 the the DT cord-035067-ic843wr9 55 9 intestinal intestinal JJ cord-035067-ic843wr9 55 10 mucosa mucosa NN cord-035067-ic843wr9 55 11 is be VBZ cord-035067-ic843wr9 55 12 associated associate VBN cord-035067-ic843wr9 55 13 with with IN cord-035067-ic843wr9 55 14 the the DT cord-035067-ic843wr9 55 15 amino amino NN cord-035067-ic843wr9 55 16 acid acid NN cord-035067-ic843wr9 55 17 carrier carrier NN cord-035067-ic843wr9 55 18 , , , cord-035067-ic843wr9 55 19 B b NN cord-035067-ic843wr9 55 20 0 0 CD cord-035067-ic843wr9 55 21 AT1 at1 NN cord-035067-ic843wr9 55 22 , , , cord-035067-ic843wr9 55 23 and and CC cord-035067-ic843wr9 55 24 regulates regulate VBZ cord-035067-ic843wr9 55 25 the the DT cord-035067-ic843wr9 55 26 intestinal intestinal JJ cord-035067-ic843wr9 55 27 flora flora NNS cord-035067-ic843wr9 55 28 . . . cord-035067-ic843wr9 56 1 This this DT cord-035067-ic843wr9 56 2 occurs occur VBZ cord-035067-ic843wr9 56 3 because because IN cord-035067-ic843wr9 56 4 this this DT cord-035067-ic843wr9 56 5 transporter transporter NN cord-035067-ic843wr9 56 6 allows allow VBZ cord-035067-ic843wr9 56 7 the the DT cord-035067-ic843wr9 56 8 absorption absorption NN cord-035067-ic843wr9 56 9 of of IN cord-035067-ic843wr9 56 10 tryptophan tryptophan NN cord-035067-ic843wr9 56 11 , , , cord-035067-ic843wr9 56 12 which which WDT cord-035067-ic843wr9 56 13 stimulates stimulate VBZ cord-035067-ic843wr9 56 14 the the DT cord-035067-ic843wr9 56 15 mTOR mtor NN cord-035067-ic843wr9 56 16 path path NN cord-035067-ic843wr9 56 17 to to TO cord-035067-ic843wr9 56 18 produce produce VB cord-035067-ic843wr9 56 19 antimicrobial antimicrobial JJ cord-035067-ic843wr9 56 20 peptides peptide NNS cord-035067-ic843wr9 56 21 . . . cord-035067-ic843wr9 57 1 Thus thus RB cord-035067-ic843wr9 57 2 , , , cord-035067-ic843wr9 57 3 the the DT cord-035067-ic843wr9 57 4 SARS SARS NNP cord-035067-ic843wr9 57 5 - - HYPH cord-035067-ic843wr9 57 6 CoV-2 CoV-2 NNP cord-035067-ic843wr9 57 7 infection infection NN cord-035067-ic843wr9 57 8 changes change VBZ cord-035067-ic843wr9 57 9 the the DT cord-035067-ic843wr9 57 10 amount amount NN cord-035067-ic843wr9 57 11 , , , cord-035067-ic843wr9 57 12 and and CC cord-035067-ic843wr9 57 13 blocks block VBZ cord-035067-ic843wr9 57 14 the the DT cord-035067-ic843wr9 57 15 ACE2 ACE2 NNP cord-035067-ic843wr9 57 16 receptors receptor NNS cord-035067-ic843wr9 57 17 in in IN cord-035067-ic843wr9 57 18 the the DT cord-035067-ic843wr9 57 19 brush brush NN cord-035067-ic843wr9 57 20 edge edge NN cord-035067-ic843wr9 57 21 , , , cord-035067-ic843wr9 57 22 causing cause VBG cord-035067-ic843wr9 57 23 tryptophan tryptophan NN cord-035067-ic843wr9 57 24 deficiency deficiency NN cord-035067-ic843wr9 57 25 and and CC cord-035067-ic843wr9 57 26 lower low JJR cord-035067-ic843wr9 57 27 production production NN cord-035067-ic843wr9 57 28 of of IN cord-035067-ic843wr9 57 29 antimicrobial antimicrobial JJ cord-035067-ic843wr9 57 30 peptides peptide NNS cord-035067-ic843wr9 57 31 , , , cord-035067-ic843wr9 57 32 which which WDT cord-035067-ic843wr9 57 33 in in IN cord-035067-ic843wr9 57 34 turn turn NN cord-035067-ic843wr9 57 35 can can MD cord-035067-ic843wr9 57 36 cause cause VB cord-035067-ic843wr9 57 37 changes change NNS cord-035067-ic843wr9 57 38 in in IN cord-035067-ic843wr9 57 39 the the DT cord-035067-ic843wr9 57 40 intestinal intestinal JJ cord-035067-ic843wr9 57 41 microbioma microbioma NN cord-035067-ic843wr9 57 42 and and CC cord-035067-ic843wr9 57 43 inflammation inflammation NN cord-035067-ic843wr9 57 44 . . . cord-035067-ic843wr9 58 1 ( ( -LRB- cord-035067-ic843wr9 58 2 7 7 CD cord-035067-ic843wr9 58 3 , , , cord-035067-ic843wr9 58 4 9 9 CD cord-035067-ic843wr9 58 5 ) ) -RRB- cord-035067-ic843wr9 58 6 Patients patient NNS cord-035067-ic843wr9 58 7 with with IN cord-035067-ic843wr9 58 8 COVID-19 covid-19 DT cord-035067-ic843wr9 58 9 present present JJ cord-035067-ic843wr9 58 10 with with IN cord-035067-ic843wr9 58 11 a a DT cord-035067-ic843wr9 58 12 great great JJ cord-035067-ic843wr9 58 13 inflammatory inflammatory JJ cord-035067-ic843wr9 58 14 reaction reaction NN cord-035067-ic843wr9 58 15 caused cause VBN cord-035067-ic843wr9 58 16 by by IN cord-035067-ic843wr9 58 17 the the DT cord-035067-ic843wr9 58 18 so so RB cord-035067-ic843wr9 58 19 - - HYPH cord-035067-ic843wr9 58 20 called call VBN cord-035067-ic843wr9 58 21 cytokine cytokine NN cord-035067-ic843wr9 58 22 storm storm NN cord-035067-ic843wr9 58 23 , , , cord-035067-ic843wr9 58 24 which which WDT cord-035067-ic843wr9 58 25 can can MD cord-035067-ic843wr9 58 26 be be VB cord-035067-ic843wr9 58 27 originated originate VBN cord-035067-ic843wr9 58 28 or or CC cord-035067-ic843wr9 58 29 potentiated potentiate VBN cord-035067-ic843wr9 58 30 by by IN cord-035067-ic843wr9 58 31 the the DT cord-035067-ic843wr9 58 32 GIT git NN cord-035067-ic843wr9 58 33 . . . cord-035067-ic843wr9 59 1 The the DT cord-035067-ic843wr9 59 2 small small JJ cord-035067-ic843wr9 59 3 intestine intestine NN cord-035067-ic843wr9 59 4 has have VBZ cord-035067-ic843wr9 59 5 the the DT cord-035067-ic843wr9 59 6 largest large JJS cord-035067-ic843wr9 59 7 amount amount NN cord-035067-ic843wr9 59 8 of of IN cord-035067-ic843wr9 59 9 lymphoid lymphoid JJ cord-035067-ic843wr9 59 10 tissue tissue NN cord-035067-ic843wr9 59 11 in in IN cord-035067-ic843wr9 59 12 the the DT cord-035067-ic843wr9 59 13 body body NN cord-035067-ic843wr9 59 14 , , , cord-035067-ic843wr9 59 15 with with IN cord-035067-ic843wr9 59 16 Peyer Peyer NNP cord-035067-ic843wr9 59 17 patches patch NNS cord-035067-ic843wr9 59 18 , , , cord-035067-ic843wr9 59 19 mesenteric mesenteric JJ cord-035067-ic843wr9 59 20 lymph lymph NN cord-035067-ic843wr9 59 21 nodes node NNS cord-035067-ic843wr9 59 22 , , , cord-035067-ic843wr9 59 23 and and CC cord-035067-ic843wr9 59 24 lymphoid lymphoid JJ cord-035067-ic843wr9 59 25 follicles follicle NNS cord-035067-ic843wr9 59 26 along along IN cord-035067-ic843wr9 59 27 the the DT cord-035067-ic843wr9 59 28 intestine intestine NN cord-035067-ic843wr9 59 29 . . . cord-035067-ic843wr9 60 1 In in IN cord-035067-ic843wr9 60 2 the the DT cord-035067-ic843wr9 60 3 mucosa mucosa NN cord-035067-ic843wr9 60 4 and and CC cord-035067-ic843wr9 60 5 below below IN cord-035067-ic843wr9 60 6 the the DT cord-035067-ic843wr9 60 7 lamina lamina JJ cord-035067-ic843wr9 60 8 propria propria NN cord-035067-ic843wr9 60 9 , , , cord-035067-ic843wr9 60 10 the the DT cord-035067-ic843wr9 60 11 intestines intestine NNS cord-035067-ic843wr9 60 12 also also RB cord-035067-ic843wr9 60 13 have have VBP cord-035067-ic843wr9 60 14 a a DT cord-035067-ic843wr9 60 15 large large JJ cord-035067-ic843wr9 60 16 population population NN cord-035067-ic843wr9 60 17 of of IN cord-035067-ic843wr9 60 18 activated activate VBN cord-035067-ic843wr9 60 19 T T NNP cord-035067-ic843wr9 60 20 cells cell NNS cord-035067-ic843wr9 60 21 , , , cord-035067-ic843wr9 60 22 plasma plasma NN cord-035067-ic843wr9 60 23 cells cell NNS cord-035067-ic843wr9 60 24 , , , cord-035067-ic843wr9 60 25 mast mast NN cord-035067-ic843wr9 60 26 cells cell NNS cord-035067-ic843wr9 60 27 , , , cord-035067-ic843wr9 60 28 dendritic dendritic JJ cord-035067-ic843wr9 60 29 cells cell NNS cord-035067-ic843wr9 60 30 , , , cord-035067-ic843wr9 60 31 and and CC cord-035067-ic843wr9 60 32 macrophages macrophage NNS cord-035067-ic843wr9 60 33 . . . cord-035067-ic843wr9 61 1 In in IN cord-035067-ic843wr9 61 2 the the DT cord-035067-ic843wr9 61 3 scenario scenario NN cord-035067-ic843wr9 61 4 of of IN cord-035067-ic843wr9 61 5 an an DT cord-035067-ic843wr9 61 6 infection infection NN cord-035067-ic843wr9 61 7 such such JJ cord-035067-ic843wr9 61 8 as as IN cord-035067-ic843wr9 61 9 COVID-19 COVID-19 NNP cord-035067-ic843wr9 61 10 , , , cord-035067-ic843wr9 61 11 there there EX cord-035067-ic843wr9 61 12 is be VBZ cord-035067-ic843wr9 61 13 an an DT cord-035067-ic843wr9 61 14 exaggerated exaggerated JJ cord-035067-ic843wr9 61 15 release release NN cord-035067-ic843wr9 61 16 of of IN cord-035067-ic843wr9 61 17 cytokines cytokine NNS cord-035067-ic843wr9 61 18 , , , cord-035067-ic843wr9 61 19 which which WDT cord-035067-ic843wr9 61 20 promote promote VBP cord-035067-ic843wr9 61 21 the the DT cord-035067-ic843wr9 61 22 recruitment recruitment NN cord-035067-ic843wr9 61 23 of of IN cord-035067-ic843wr9 61 24 several several JJ cord-035067-ic843wr9 61 25 other other JJ cord-035067-ic843wr9 61 26 cells cell NNS cord-035067-ic843wr9 61 27 , , , cord-035067-ic843wr9 61 28 causing cause VBG cord-035067-ic843wr9 61 29 a a DT cord-035067-ic843wr9 61 30 great great JJ cord-035067-ic843wr9 61 31 inflammatory inflammatory JJ cord-035067-ic843wr9 61 32 process process NN cord-035067-ic843wr9 61 33 . . . cord-035067-ic843wr9 62 1 ( ( -LRB- cord-035067-ic843wr9 62 2 9 9 CD cord-035067-ic843wr9 62 3 , , , cord-035067-ic843wr9 62 4 10 10 CD cord-035067-ic843wr9 62 5 ) ) -RRB- cord-035067-ic843wr9 62 6 Studies study NNS cord-035067-ic843wr9 62 7 point point VBP cord-035067-ic843wr9 62 8 out out RP cord-035067-ic843wr9 62 9 that that IN cord-035067-ic843wr9 62 10 interferon interferon NN cord-035067-ic843wr9 62 11 and and CC cord-035067-ic843wr9 62 12 influenza influenza NN cord-035067-ic843wr9 62 13 virus virus NN cord-035067-ic843wr9 62 14 infection infection NN cord-035067-ic843wr9 62 15 ( ( -LRB- cord-035067-ic843wr9 62 16 interferon interferon NN cord-035067-ic843wr9 62 17 pathway pathway NN cord-035067-ic843wr9 62 18 inducer inducer NN cord-035067-ic843wr9 62 19 ) ) -RRB- cord-035067-ic843wr9 62 20 may may MD cord-035067-ic843wr9 62 21 be be VB cord-035067-ic843wr9 62 22 related relate VBN cord-035067-ic843wr9 62 23 to to IN cord-035067-ic843wr9 62 24 increased increase VBN cord-035067-ic843wr9 62 25 ACE2 ACE2 NNP cord-035067-ic843wr9 62 26 transcription transcription NN cord-035067-ic843wr9 62 27 . . . cord-035067-ic843wr9 63 1 ( ( -LRB- cord-035067-ic843wr9 63 2 11 11 CD cord-035067-ic843wr9 63 3 ) ) -RRB- cord-035067-ic843wr9 63 4 Smokers smoker NNS cord-035067-ic843wr9 63 5 and and CC cord-035067-ic843wr9 63 6 patients patient NNS cord-035067-ic843wr9 63 7 with with IN cord-035067-ic843wr9 63 8 chronic chronic JJ cord-035067-ic843wr9 63 9 obstructive obstructive JJ cord-035067-ic843wr9 63 10 pulmonary pulmonary JJ cord-035067-ic843wr9 63 11 disease disease NN cord-035067-ic843wr9 63 12 ( ( -LRB- cord-035067-ic843wr9 63 13 COPD COPD NNP cord-035067-ic843wr9 63 14 ) ) -RRB- cord-035067-ic843wr9 63 15 also also RB cord-035067-ic843wr9 63 16 have have VBP cord-035067-ic843wr9 63 17 a a DT cord-035067-ic843wr9 63 18 higher high JJR cord-035067-ic843wr9 63 19 expression expression NN cord-035067-ic843wr9 63 20 of of IN cord-035067-ic843wr9 63 21 ACE2 ACE2 NNP cord-035067-ic843wr9 63 22 receptors receptor NNS cord-035067-ic843wr9 63 23 . . . cord-035067-ic843wr9 64 1 ( ( -LRB- cord-035067-ic843wr9 64 2 12 12 CD cord-035067-ic843wr9 64 3 ) ) -RRB- cord-035067-ic843wr9 65 1 In in IN cord-035067-ic843wr9 65 2 addition addition NN cord-035067-ic843wr9 65 3 , , , cord-035067-ic843wr9 65 4 einstein einstein NNP cord-035067-ic843wr9 65 5 ( ( -LRB- cord-035067-ic843wr9 65 6 São São NNP cord-035067-ic843wr9 65 7 Paulo Paulo NNP cord-035067-ic843wr9 65 8 ) ) -RRB- cord-035067-ic843wr9 65 9 . . . cord-035067-ic843wr9 66 1 2020;18:1 2020;18:1 CD cord-035067-ic843wr9 66 2 - - SYM cord-035067-ic843wr9 66 3 14 14 CD cord-035067-ic843wr9 66 4 diabetes diabetes NN cord-035067-ic843wr9 66 5 and and CC cord-035067-ic843wr9 66 6 hypertension hypertension NN cord-035067-ic843wr9 66 7 have have VBP cord-035067-ic843wr9 66 8 been be VBN cord-035067-ic843wr9 66 9 associated associate VBN cord-035067-ic843wr9 66 10 with with IN cord-035067-ic843wr9 66 11 polymorphisms polymorphism NNS cord-035067-ic843wr9 66 12 of of IN cord-035067-ic843wr9 66 13 the the DT cord-035067-ic843wr9 66 14 ACE2 ACE2 NNP cord-035067-ic843wr9 66 15 gene gene NN cord-035067-ic843wr9 66 16 . . . cord-035067-ic843wr9 67 1 ( ( -LRB- cord-035067-ic843wr9 67 2 7 7 CD cord-035067-ic843wr9 67 3 ) ) -RRB- cord-035067-ic843wr9 67 4 Drugs drug NNS cord-035067-ic843wr9 67 5 used use VBN cord-035067-ic843wr9 67 6 in in IN cord-035067-ic843wr9 67 7 the the DT cord-035067-ic843wr9 67 8 treatment treatment NN cord-035067-ic843wr9 67 9 of of IN cord-035067-ic843wr9 67 10 hypertension hypertension NN cord-035067-ic843wr9 67 11 , , , cord-035067-ic843wr9 67 12 such such JJ cord-035067-ic843wr9 67 13 as as IN cord-035067-ic843wr9 67 14 ACE ace NN cord-035067-ic843wr9 67 15 inhibitors inhibitor NNS cord-035067-ic843wr9 67 16 ( ( -LRB- cord-035067-ic843wr9 67 17 ACEi ACEi NNP cord-035067-ic843wr9 67 18 ) ) -RRB- cord-035067-ic843wr9 67 19 and and CC cord-035067-ic843wr9 67 20 angiotensin angiotensin NN cord-035067-ic843wr9 67 21 receptor receptor NN cord-035067-ic843wr9 67 22 blockers blocker NNS cord-035067-ic843wr9 67 23 ( ( -LRB- cord-035067-ic843wr9 67 24 ARB ARB NNP cord-035067-ic843wr9 67 25 ) ) -RRB- cord-035067-ic843wr9 67 26 , , , cord-035067-ic843wr9 67 27 reduce reduce VB cord-035067-ic843wr9 67 28 inflammation inflammation NN cord-035067-ic843wr9 67 29 by by IN cord-035067-ic843wr9 67 30 decreasing decrease VBG cord-035067-ic843wr9 67 31 cytokines cytokine NNS cord-035067-ic843wr9 67 32 . . . cord-035067-ic843wr9 68 1 In in IN cord-035067-ic843wr9 68 2 addition addition NN cord-035067-ic843wr9 68 3 , , , cord-035067-ic843wr9 68 4 they -PRON- PRP cord-035067-ic843wr9 68 5 may may MD cord-035067-ic843wr9 68 6 increase increase VB cord-035067-ic843wr9 68 7 the the DT cord-035067-ic843wr9 68 8 expression expression NN cord-035067-ic843wr9 68 9 of of IN cord-035067-ic843wr9 68 10 ACE2 ACE2 NNP cord-035067-ic843wr9 68 11 . . . cord-035067-ic843wr9 69 1 ( ( -LRB- cord-035067-ic843wr9 69 2 13 13 CD cord-035067-ic843wr9 69 3 ) ) -RRB- cord-035067-ic843wr9 70 1 However however RB cord-035067-ic843wr9 70 2 , , , cord-035067-ic843wr9 70 3 the the DT cord-035067-ic843wr9 70 4 use use NN cord-035067-ic843wr9 70 5 of of IN cord-035067-ic843wr9 70 6 ACEi ACEi NNP cord-035067-ic843wr9 70 7 and and CC cord-035067-ic843wr9 70 8 ARB ARB NNP cord-035067-ic843wr9 70 9 has have VBZ cord-035067-ic843wr9 70 10 not not RB cord-035067-ic843wr9 70 11 been be VBN cord-035067-ic843wr9 70 12 associated associate VBN cord-035067-ic843wr9 70 13 with with IN cord-035067-ic843wr9 70 14 a a DT cord-035067-ic843wr9 70 15 worse bad JJR cord-035067-ic843wr9 70 16 clinical clinical JJ cord-035067-ic843wr9 70 17 evolution evolution NN cord-035067-ic843wr9 70 18 in in IN cord-035067-ic843wr9 70 19 patients patient NNS cord-035067-ic843wr9 70 20 with with IN cord-035067-ic843wr9 70 21 COVID-19 COVID-19 NNP cord-035067-ic843wr9 70 22 . . . cord-035067-ic843wr9 71 1 Thus thus RB cord-035067-ic843wr9 71 2 , , , cord-035067-ic843wr9 71 3 maintenance maintenance NN cord-035067-ic843wr9 71 4 of of IN cord-035067-ic843wr9 71 5 the the DT cord-035067-ic843wr9 71 6 use use NN cord-035067-ic843wr9 71 7 of of IN cord-035067-ic843wr9 71 8 these these DT cord-035067-ic843wr9 71 9 drugs drug NNS cord-035067-ic843wr9 71 10 in in IN cord-035067-ic843wr9 71 11 hypertensive hypertensive JJ cord-035067-ic843wr9 71 12 patients patient NNS cord-035067-ic843wr9 71 13 is be VBZ cord-035067-ic843wr9 71 14 recommended recommend VBN cord-035067-ic843wr9 71 15 . . . cord-035067-ic843wr9 72 1 ( ( -LRB- cord-035067-ic843wr9 72 2 14 14 CD cord-035067-ic843wr9 72 3 , , , cord-035067-ic843wr9 72 4 15 15 CD cord-035067-ic843wr9 72 5 ) ) -RRB- cord-035067-ic843wr9 73 1 While while IN cord-035067-ic843wr9 73 2 the the DT cord-035067-ic843wr9 73 3 SARS SARS NNP cord-035067-ic843wr9 73 4 - - HYPH cord-035067-ic843wr9 73 5 CoV CoV NNP cord-035067-ic843wr9 73 6 and and CC cord-035067-ic843wr9 73 7 SARS SARS NNP cord-035067-ic843wr9 73 8 - - HYPH cord-035067-ic843wr9 73 9 CoV-2 CoV-2 NNP cord-035067-ic843wr9 73 10 viruses virus NNS cord-035067-ic843wr9 73 11 use use VBP cord-035067-ic843wr9 73 12 ACE2 ACE2 NNP cord-035067-ic843wr9 73 13 as as IN cord-035067-ic843wr9 73 14 a a DT cord-035067-ic843wr9 73 15 mediator mediator NN cord-035067-ic843wr9 73 16 to to TO cord-035067-ic843wr9 73 17 enter enter VB cord-035067-ic843wr9 73 18 the the DT cord-035067-ic843wr9 73 19 cells cell NNS cord-035067-ic843wr9 73 20 , , , cord-035067-ic843wr9 73 21 MERS MERS NNP cord-035067-ic843wr9 73 22 - - HYPH cord-035067-ic843wr9 73 23 CoV CoV NNP cord-035067-ic843wr9 73 24 uses use VBZ cord-035067-ic843wr9 73 25 dipeptidyl dipeptidyl NN cord-035067-ic843wr9 73 26 - - HYPH cord-035067-ic843wr9 73 27 peptidase peptidase NN cord-035067-ic843wr9 73 28 4 4 CD cord-035067-ic843wr9 73 29 ( ( -LRB- cord-035067-ic843wr9 73 30 DPP4 DPP4 NNP cord-035067-ic843wr9 73 31 ) ) -RRB- cord-035067-ic843wr9 73 32 . . . cord-035067-ic843wr9 74 1 ( ( -LRB- cord-035067-ic843wr9 74 2 7 7 LS cord-035067-ic843wr9 74 3 ) ) -RRB- cord-035067-ic843wr9 74 4 Because because IN cord-035067-ic843wr9 74 5 they -PRON- PRP cord-035067-ic843wr9 74 6 are be VBP cord-035067-ic843wr9 74 7 viruses virus NNS cord-035067-ic843wr9 74 8 from from IN cord-035067-ic843wr9 74 9 the the DT cord-035067-ic843wr9 74 10 same same JJ cord-035067-ic843wr9 74 11 family family NN cord-035067-ic843wr9 74 12 , , , cord-035067-ic843wr9 74 13 some some DT cord-035067-ic843wr9 74 14 authors author NNS cord-035067-ic843wr9 74 15 have have VBP cord-035067-ic843wr9 74 16 studied study VBN cord-035067-ic843wr9 74 17 whether whether IN cord-035067-ic843wr9 74 18 DPP4 DPP4 NNP cord-035067-ic843wr9 74 19 is be VBZ cord-035067-ic843wr9 74 20 also also RB cord-035067-ic843wr9 74 21 involved involve VBN cord-035067-ic843wr9 74 22 in in IN cord-035067-ic843wr9 74 23 the the DT cord-035067-ic843wr9 74 24 infection infection NN cord-035067-ic843wr9 74 25 mechanism mechanism NN cord-035067-ic843wr9 74 26 of of IN cord-035067-ic843wr9 74 27 the the DT cord-035067-ic843wr9 74 28 new new JJ cord-035067-ic843wr9 74 29 disease disease NN cord-035067-ic843wr9 74 30 . . . cord-035067-ic843wr9 75 1 According accord VBG cord-035067-ic843wr9 75 2 to to IN cord-035067-ic843wr9 75 3 Vankadari Vankadari NNP cord-035067-ic843wr9 75 4 et et FW cord-035067-ic843wr9 75 5 al al NNP cord-035067-ic843wr9 75 6 . . NNP cord-035067-ic843wr9 75 7 , , , cord-035067-ic843wr9 75 8 the the DT cord-035067-ic843wr9 75 9 S1 S1 NNP cord-035067-ic843wr9 75 10 domain domain NN cord-035067-ic843wr9 75 11 of of IN cord-035067-ic843wr9 75 12 the the DT cord-035067-ic843wr9 75 13 SARS SARS NNP cord-035067-ic843wr9 75 14 - - HYPH cord-035067-ic843wr9 75 15 CoV-2 CoV-2 NNP cord-035067-ic843wr9 75 16 membrane membrane NN cord-035067-ic843wr9 75 17 glycoprotein glycoprotein NN cord-035067-ic843wr9 75 18 , , , cord-035067-ic843wr9 75 19 besides besides IN cord-035067-ic843wr9 75 20 interacting interact VBG cord-035067-ic843wr9 75 21 with with IN cord-035067-ic843wr9 75 22 ACE2 ACE2 NNP cord-035067-ic843wr9 75 23 , , , cord-035067-ic843wr9 75 24 the the DT cord-035067-ic843wr9 75 25 main main JJ cord-035067-ic843wr9 75 26 gateway gateway NN cord-035067-ic843wr9 75 27 for for IN cord-035067-ic843wr9 75 28 the the DT cord-035067-ic843wr9 75 29 new new JJ cord-035067-ic843wr9 75 30 virus virus NN cord-035067-ic843wr9 75 31 may may MD cord-035067-ic843wr9 75 32 have have VB cord-035067-ic843wr9 75 33 some some DT cord-035067-ic843wr9 75 34 relation relation NN cord-035067-ic843wr9 75 35 with with IN cord-035067-ic843wr9 75 36 DPP4 DPP4 NNP cord-035067-ic843wr9 75 37 . . . cord-035067-ic843wr9 76 1 ( ( -LRB- cord-035067-ic843wr9 76 2 16 16 CD cord-035067-ic843wr9 76 3 ) ) -RRB- cord-035067-ic843wr9 77 1 However however RB cord-035067-ic843wr9 77 2 , , , cord-035067-ic843wr9 77 3 the the DT cord-035067-ic843wr9 77 4 study study NN cord-035067-ic843wr9 77 5 by by IN cord-035067-ic843wr9 77 6 Tai Tai NNP cord-035067-ic843wr9 77 7 et et NNP cord-035067-ic843wr9 77 8 al al NNP cord-035067-ic843wr9 77 9 . . NNP cord-035067-ic843wr9 77 10 , , , cord-035067-ic843wr9 77 11 found find VBD cord-035067-ic843wr9 77 12 that that IN cord-035067-ic843wr9 77 13 the the DT cord-035067-ic843wr9 77 14 virus virus NN cord-035067-ic843wr9 77 15 did do VBD cord-035067-ic843wr9 77 16 not not RB cord-035067-ic843wr9 77 17 bind bind VB cord-035067-ic843wr9 77 18 to to IN cord-035067-ic843wr9 77 19 293 293 CD cord-035067-ic843wr9 77 20 T t NN cord-035067-ic843wr9 77 21 cells cell NNS cord-035067-ic843wr9 77 22 that that WDT cord-035067-ic843wr9 77 23 expressed express VBD cord-035067-ic843wr9 77 24 only only RB cord-035067-ic843wr9 77 25 DPP4 DPP4 NNP cord-035067-ic843wr9 77 26 . . . cord-035067-ic843wr9 78 1 This this DT cord-035067-ic843wr9 78 2 connection connection NN cord-035067-ic843wr9 78 3 only only RB cord-035067-ic843wr9 78 4 occurred occur VBD cord-035067-ic843wr9 78 5 in in IN cord-035067-ic843wr9 78 6 293 293 CD cord-035067-ic843wr9 78 7 T t NN cord-035067-ic843wr9 78 8 cells cell NNS cord-035067-ic843wr9 78 9 with with IN cord-035067-ic843wr9 78 10 ACE2 ACE2 NNP cord-035067-ic843wr9 78 11 . . . cord-035067-ic843wr9 79 1 ( ( -LRB- cord-035067-ic843wr9 79 2 17 17 CD cord-035067-ic843wr9 79 3 ) ) -RRB- cord-035067-ic843wr9 80 1 Several several JJ cord-035067-ic843wr9 80 2 articles article NNS cord-035067-ic843wr9 80 3 on on IN cord-035067-ic843wr9 80 4 GIT git NN cord-035067-ic843wr9 80 5 - - HYPH cord-035067-ic843wr9 80 6 related relate VBN cord-035067-ic843wr9 80 7 symptoms symptom NNS cord-035067-ic843wr9 80 8 of of IN cord-035067-ic843wr9 80 9 COVID-19 COVID-19 NNP cord-035067-ic843wr9 80 10 and and CC cord-035067-ic843wr9 80 11 its -PRON- PRP$ cord-035067-ic843wr9 80 12 possible possible JJ cord-035067-ic843wr9 80 13 oral oral JJ cord-035067-ic843wr9 80 14 - - HYPH cord-035067-ic843wr9 80 15 fecal fecal NN cord-035067-ic843wr9 80 16 transmission transmission NN cord-035067-ic843wr9 80 17 have have VBP cord-035067-ic843wr9 80 18 been be VBN cord-035067-ic843wr9 80 19 published publish VBN cord-035067-ic843wr9 80 20 , , , cord-035067-ic843wr9 80 21 with with IN cord-035067-ic843wr9 80 22 divergent divergent JJ cord-035067-ic843wr9 80 23 results result NNS cord-035067-ic843wr9 80 24 . . . cord-035067-ic843wr9 81 1 The the DT cord-035067-ic843wr9 81 2 objective objective NN cord-035067-ic843wr9 81 3 of of IN cord-035067-ic843wr9 81 4 this this DT cord-035067-ic843wr9 81 5 study study NN cord-035067-ic843wr9 81 6 was be VBD cord-035067-ic843wr9 81 7 to to TO cord-035067-ic843wr9 81 8 review review VB cord-035067-ic843wr9 81 9 the the DT cord-035067-ic843wr9 81 10 literature literature NN cord-035067-ic843wr9 81 11 related relate VBN cord-035067-ic843wr9 81 12 to to IN cord-035067-ic843wr9 81 13 the the DT cord-035067-ic843wr9 81 14 prevalence prevalence NN cord-035067-ic843wr9 81 15 of of IN cord-035067-ic843wr9 81 16 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 81 17 symptoms symptom NNS cord-035067-ic843wr9 81 18 , , , cord-035067-ic843wr9 81 19 and and CC cord-035067-ic843wr9 81 20 to to TO cord-035067-ic843wr9 81 21 verify verify VB cord-035067-ic843wr9 81 22 the the DT cord-035067-ic843wr9 81 23 possibility possibility NN cord-035067-ic843wr9 81 24 of of IN cord-035067-ic843wr9 81 25 fecal fecal JJ cord-035067-ic843wr9 81 26 - - HYPH cord-035067-ic843wr9 81 27 oral oral JJ cord-035067-ic843wr9 81 28 transmission transmission NN cord-035067-ic843wr9 81 29 of of IN cord-035067-ic843wr9 81 30 the the DT cord-035067-ic843wr9 81 31 disease disease NN cord-035067-ic843wr9 81 32 . . . cord-035067-ic843wr9 82 1 The the DT cord-035067-ic843wr9 82 2 database database NN cord-035067-ic843wr9 82 3 chosen choose VBN cord-035067-ic843wr9 82 4 for for IN cord-035067-ic843wr9 82 5 this this DT cord-035067-ic843wr9 82 6 work work NN cord-035067-ic843wr9 82 7 was be VBD cord-035067-ic843wr9 82 8 PubMed PubMed NNP cord-035067-ic843wr9 82 9 ® ® NNP cord-035067-ic843wr9 82 10 . . . cord-035067-ic843wr9 83 1 On on IN cord-035067-ic843wr9 83 2 May May NNP cord-035067-ic843wr9 83 3 5 5 CD cord-035067-ic843wr9 83 4 , , , cord-035067-ic843wr9 83 5 2020 2020 CD cord-035067-ic843wr9 83 6 , , , cord-035067-ic843wr9 83 7 we -PRON- PRP cord-035067-ic843wr9 83 8 searched search VBD cord-035067-ic843wr9 83 9 for for IN cord-035067-ic843wr9 83 10 articles article NNS cord-035067-ic843wr9 83 11 with with IN cord-035067-ic843wr9 83 12 the the DT cord-035067-ic843wr9 83 13 words word NNS cord-035067-ic843wr9 83 14 " " `` cord-035067-ic843wr9 83 15 COVID-19 COVID-19 NNP cord-035067-ic843wr9 83 16 " " '' cord-035067-ic843wr9 83 17 or or CC cord-035067-ic843wr9 83 18 " " `` cord-035067-ic843wr9 83 19 SARS SARS NNP cord-035067-ic843wr9 83 20 - - HYPH cord-035067-ic843wr9 83 21 CoV-2 CoV-2 NNP cord-035067-ic843wr9 83 22 " " '' cord-035067-ic843wr9 83 23 and and CC cord-035067-ic843wr9 83 24 " " `` cord-035067-ic843wr9 83 25 GIT GIT NNP cord-035067-ic843wr9 83 26 " " '' cord-035067-ic843wr9 83 27 or or CC cord-035067-ic843wr9 83 28 " " `` cord-035067-ic843wr9 83 29 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 83 30 " " '' cord-035067-ic843wr9 83 31 or or CC cord-035067-ic843wr9 83 32 " " `` cord-035067-ic843wr9 83 33 enteric enteric JJ cord-035067-ic843wr9 83 34 . . . cord-035067-ic843wr9 83 35 " " '' cord-035067-ic843wr9 84 1 A a DT cord-035067-ic843wr9 84 2 total total NN cord-035067-ic843wr9 84 3 of of IN cord-035067-ic843wr9 84 4 179 179 CD cord-035067-ic843wr9 84 5 articles article NNS cord-035067-ic843wr9 84 6 resulted result VBD cord-035067-ic843wr9 84 7 from from IN cord-035067-ic843wr9 84 8 this this DT cord-035067-ic843wr9 84 9 search search NN cord-035067-ic843wr9 84 10 . . . cord-035067-ic843wr9 85 1 The the DT cord-035067-ic843wr9 85 2 inclusion inclusion NN cord-035067-ic843wr9 85 3 criteria criterion NNS cord-035067-ic843wr9 85 4 for for IN cord-035067-ic843wr9 85 5 the the DT cord-035067-ic843wr9 85 6 studies study NNS cord-035067-ic843wr9 85 7 in in IN cord-035067-ic843wr9 85 8 this this DT cord-035067-ic843wr9 85 9 review review NN cord-035067-ic843wr9 85 10 were be VBD cord-035067-ic843wr9 85 11 the the DT cord-035067-ic843wr9 85 12 fulfillment fulfillment NN cord-035067-ic843wr9 85 13 of of IN cord-035067-ic843wr9 85 14 eligibility eligibility NN cord-035067-ic843wr9 85 15 criteria criterion NNS cord-035067-ic843wr9 86 1 ( ( -LRB- cord-035067-ic843wr9 86 2 articles article NNS cord-035067-ic843wr9 86 3 addressing address VBG cord-035067-ic843wr9 86 4 SARS SARS NNP cord-035067-ic843wr9 86 5 - - HYPH cord-035067-ic843wr9 86 6 CoV-2 CoV-2 NNP cord-035067-ic843wr9 86 7 infection infection NN cord-035067-ic843wr9 86 8 and and CC cord-035067-ic843wr9 86 9 GIT GIT NNP cord-035067-ic843wr9 86 10 symptoms symptom NNS cord-035067-ic843wr9 86 11 ) ) -RRB- cord-035067-ic843wr9 86 12 , , , cord-035067-ic843wr9 86 13 articles article NNS cord-035067-ic843wr9 86 14 in in IN cord-035067-ic843wr9 86 15 English English NNP cord-035067-ic843wr9 86 16 , , , cord-035067-ic843wr9 86 17 and and CC cord-035067-ic843wr9 86 18 samples sample NNS cord-035067-ic843wr9 86 19 with with IN cord-035067-ic843wr9 86 20 more more JJR cord-035067-ic843wr9 86 21 than than IN cord-035067-ic843wr9 86 22 50 50 CD cord-035067-ic843wr9 86 23 patients patient NNS cord-035067-ic843wr9 86 24 . . . cord-035067-ic843wr9 87 1 Exclusion exclusion NN cord-035067-ic843wr9 87 2 criteria criterion NNS cord-035067-ic843wr9 87 3 were be VBD cord-035067-ic843wr9 87 4 study study NN cord-035067-ic843wr9 87 5 design design NN cord-035067-ic843wr9 87 6 of of IN cord-035067-ic843wr9 87 7 case case NN cord-035067-ic843wr9 87 8 reports report NNS cord-035067-ic843wr9 87 9 , , , cord-035067-ic843wr9 87 10 reviews review NNS cord-035067-ic843wr9 87 11 on on IN cord-035067-ic843wr9 87 12 the the DT cord-035067-ic843wr9 87 13 infection infection NN cord-035067-ic843wr9 87 14 mechanism mechanism NN cord-035067-ic843wr9 87 15 and and CC cord-035067-ic843wr9 87 16 virus virus NN cord-035067-ic843wr9 87 17 , , , cord-035067-ic843wr9 87 18 GIT git NN cord-035067-ic843wr9 87 19 - - HYPH cord-035067-ic843wr9 87 20 related relate VBN cord-035067-ic843wr9 87 21 procedure procedure NN cord-035067-ic843wr9 87 22 recommendation recommendation NN cord-035067-ic843wr9 87 23 manuals manual NNS cord-035067-ic843wr9 87 24 in in IN cord-035067-ic843wr9 87 25 infected infected JJ cord-035067-ic843wr9 87 26 patients patient NNS cord-035067-ic843wr9 87 27 , , , cord-035067-ic843wr9 87 28 articles article NNS cord-035067-ic843wr9 87 29 in in IN cord-035067-ic843wr9 87 30 languages language NNS cord-035067-ic843wr9 87 31 other other JJ cord-035067-ic843wr9 87 32 than than IN cord-035067-ic843wr9 87 33 English English NNP cord-035067-ic843wr9 87 34 , , , cord-035067-ic843wr9 87 35 and and CC cord-035067-ic843wr9 87 36 less less JJR cord-035067-ic843wr9 87 37 than than IN cord-035067-ic843wr9 87 38 50 50 CD cord-035067-ic843wr9 87 39 patients patient NNS cord-035067-ic843wr9 87 40 evaluated evaluate VBN cord-035067-ic843wr9 87 41 . . . cord-035067-ic843wr9 88 1 Figure figure NN cord-035067-ic843wr9 88 2 1 1 CD cord-035067-ic843wr9 88 3 shows show VBZ cord-035067-ic843wr9 88 4 the the DT cord-035067-ic843wr9 88 5 diagram diagram NN cord-035067-ic843wr9 88 6 Preferred Preferred NNP cord-035067-ic843wr9 88 7 Reporting Reporting NNP cord-035067-ic843wr9 88 8 Items Items NNPS cord-035067-ic843wr9 88 9 for for IN cord-035067-ic843wr9 88 10 Systematic Systematic NNP cord-035067-ic843wr9 88 11 Reviews Reviews NNPS cord-035067-ic843wr9 88 12 and and CC cord-035067-ic843wr9 88 13 Meta Meta NNP cord-035067-ic843wr9 88 14 - - HYPH cord-035067-ic843wr9 88 15 Analyses Analyses NNP cord-035067-ic843wr9 88 16 ( ( -LRB- cord-035067-ic843wr9 88 17 PRISMA PRISMA NNP cord-035067-ic843wr9 88 18 ) ) -RRB- cord-035067-ic843wr9 88 19 performed perform VBD cord-035067-ic843wr9 88 20 based base VBN cord-035067-ic843wr9 88 21 on on IN cord-035067-ic843wr9 88 22 reading read VBG cord-035067-ic843wr9 88 23 titles title NNS cord-035067-ic843wr9 88 24 and and CC cord-035067-ic843wr9 88 25 abstracts abstract NNS cord-035067-ic843wr9 88 26 ; ; : cord-035067-ic843wr9 88 27 161 161 CD cord-035067-ic843wr9 88 28 articles article NNS cord-035067-ic843wr9 88 29 were be VBD cord-035067-ic843wr9 88 30 eliminated eliminate VBN cord-035067-ic843wr9 88 31 , , , cord-035067-ic843wr9 88 32 leaving leave VBG cord-035067-ic843wr9 88 33 18 18 CD cord-035067-ic843wr9 88 34 articles article NNS cord-035067-ic843wr9 88 35 . . . cord-035067-ic843wr9 89 1 One one CD cord-035067-ic843wr9 89 2 last last JJ cord-035067-ic843wr9 89 3 article article NN cord-035067-ic843wr9 89 4 was be VBD cord-035067-ic843wr9 89 5 added add VBN cord-035067-ic843wr9 89 6 later later RB cord-035067-ic843wr9 89 7 . . . cord-035067-ic843wr9 90 1 Of of IN cord-035067-ic843wr9 90 2 these these DT cord-035067-ic843wr9 90 3 19 19 CD cord-035067-ic843wr9 90 4 articles article NNS cord-035067-ic843wr9 90 5 , , , cord-035067-ic843wr9 90 6 four four CD cord-035067-ic843wr9 90 7 were be VBD cord-035067-ic843wr9 90 8 reviews review NNS cord-035067-ic843wr9 90 9 about about IN cord-035067-ic843wr9 90 10 the the DT cord-035067-ic843wr9 90 11 virus virus NN cord-035067-ic843wr9 90 12 and and CC cord-035067-ic843wr9 90 13 its -PRON- PRP$ cord-035067-ic843wr9 90 14 mechanism mechanism NN cord-035067-ic843wr9 90 15 of of IN cord-035067-ic843wr9 90 16 infection infection NN cord-035067-ic843wr9 90 17 , , , cord-035067-ic843wr9 90 18 which which WDT cord-035067-ic843wr9 90 19 were be VBD cord-035067-ic843wr9 90 20 disregarded disregard VBN cord-035067-ic843wr9 90 21 . . . cord-035067-ic843wr9 91 1 Finally finally RB cord-035067-ic843wr9 91 2 , , , cord-035067-ic843wr9 91 3 a a DT cord-035067-ic843wr9 91 4 study study NN cord-035067-ic843wr9 91 5 including include VBG cord-035067-ic843wr9 91 6 only only RB cord-035067-ic843wr9 91 7 ten ten CD cord-035067-ic843wr9 91 8 patients patient NNS cord-035067-ic843wr9 91 9 was be VBD cord-035067-ic843wr9 91 10 eliminated eliminate VBN cord-035067-ic843wr9 91 11 . . . cord-035067-ic843wr9 92 1 With with IN cord-035067-ic843wr9 92 2 this this DT cord-035067-ic843wr9 92 3 , , , cord-035067-ic843wr9 92 4 the the DT cord-035067-ic843wr9 92 5 review review NN cord-035067-ic843wr9 92 6 was be VBD cord-035067-ic843wr9 92 7 carried carry VBN cord-035067-ic843wr9 92 8 out out RP cord-035067-ic843wr9 92 9 with with IN cord-035067-ic843wr9 92 10 14 14 CD cord-035067-ic843wr9 92 11 articles article NNS cord-035067-ic843wr9 92 12 , , , cord-035067-ic843wr9 92 13 in in IN cord-035067-ic843wr9 92 14 that that DT cord-035067-ic843wr9 92 15 four four CD cord-035067-ic843wr9 92 16 were be VBD cord-035067-ic843wr9 92 17 metaanalyses metaanalyse NNS cord-035067-ic843wr9 92 18 , , , cord-035067-ic843wr9 92 19 one one CD cord-035067-ic843wr9 92 20 systematic systematic JJ cord-035067-ic843wr9 92 21 review review NN cord-035067-ic843wr9 92 22 , , , cord-035067-ic843wr9 92 23 and and CC cord-035067-ic843wr9 92 24 nine nine CD cord-035067-ic843wr9 92 25 retrospective retrospective JJ cord-035067-ic843wr9 92 26 studies study NNS cord-035067-ic843wr9 92 27 . . . cord-035067-ic843wr9 93 1 The the DT cord-035067-ic843wr9 93 2 analysis analysis NN cord-035067-ic843wr9 93 3 of of IN cord-035067-ic843wr9 93 4 the the DT cord-035067-ic843wr9 93 5 articles article NNS cord-035067-ic843wr9 93 6 was be VBD cord-035067-ic843wr9 93 7 initially initially RB cord-035067-ic843wr9 93 8 made make VBN cord-035067-ic843wr9 93 9 by by IN cord-035067-ic843wr9 93 10 the the DT cord-035067-ic843wr9 93 11 author author NN cord-035067-ic843wr9 93 12 , , , cord-035067-ic843wr9 93 13 but but CC cord-035067-ic843wr9 93 14 the the DT cord-035067-ic843wr9 93 15 final final JJ cord-035067-ic843wr9 93 16 choice choice NN cord-035067-ic843wr9 93 17 also also RB cord-035067-ic843wr9 93 18 included include VBD cord-035067-ic843wr9 93 19 a a DT cord-035067-ic843wr9 93 20 senior senior JJ cord-035067-ic843wr9 93 21 reviewer reviewer NN cord-035067-ic843wr9 93 22 . . . cord-035067-ic843wr9 94 1 Due due IN cord-035067-ic843wr9 94 2 to to IN cord-035067-ic843wr9 94 3 the the DT cord-035067-ic843wr9 94 4 small small JJ cord-035067-ic843wr9 94 5 number number NN cord-035067-ic843wr9 94 6 of of IN cord-035067-ic843wr9 94 7 large large JJ cord-035067-ic843wr9 94 8 studies study NNS cord-035067-ic843wr9 94 9 related relate VBN cord-035067-ic843wr9 94 10 to to IN cord-035067-ic843wr9 94 11 this this DT cord-035067-ic843wr9 94 12 subject subject NN cord-035067-ic843wr9 94 13 , , , cord-035067-ic843wr9 94 14 and and CC cord-035067-ic843wr9 94 15 the the DT cord-035067-ic843wr9 94 16 importance importance NN cord-035067-ic843wr9 94 17 and and CC cord-035067-ic843wr9 94 18 urgency urgency NN cord-035067-ic843wr9 94 19 of of IN cord-035067-ic843wr9 94 20 the the DT cord-035067-ic843wr9 94 21 topic topic NN cord-035067-ic843wr9 94 22 , , , cord-035067-ic843wr9 94 23 several several JJ cord-035067-ic843wr9 94 24 variations variation NNS cord-035067-ic843wr9 94 25 of of IN cord-035067-ic843wr9 94 26 study study NN cord-035067-ic843wr9 94 27 designs design NNS cord-035067-ic843wr9 94 28 were be VBD cord-035067-ic843wr9 94 29 included include VBN cord-035067-ic843wr9 94 30 . . . cord-035067-ic843wr9 95 1 Information information NN cord-035067-ic843wr9 95 2 on on IN cord-035067-ic843wr9 95 3 country country NN cord-035067-ic843wr9 95 4 of of IN cord-035067-ic843wr9 95 5 origin origin NN cord-035067-ic843wr9 95 6 , , , cord-035067-ic843wr9 95 7 mean mean JJ cord-035067-ic843wr9 95 8 age age NN cord-035067-ic843wr9 95 9 , , , cord-035067-ic843wr9 95 10 different different JJ cord-035067-ic843wr9 95 11 comorbidities comorbiditie NNS cord-035067-ic843wr9 95 12 , , , cord-035067-ic843wr9 95 13 typical typical JJ cord-035067-ic843wr9 95 14 symptoms symptom NNS cord-035067-ic843wr9 95 15 ( ( -LRB- cord-035067-ic843wr9 95 16 fever fever NN cord-035067-ic843wr9 95 17 , , , cord-035067-ic843wr9 95 18 cough cough NN cord-035067-ic843wr9 95 19 , , , cord-035067-ic843wr9 95 20 and and CC cord-035067-ic843wr9 95 21 dyspnea dyspnea NN cord-035067-ic843wr9 95 22 , , , cord-035067-ic843wr9 95 23 among among IN cord-035067-ic843wr9 95 24 others other NNS cord-035067-ic843wr9 95 25 ) ) -RRB- cord-035067-ic843wr9 95 26 , , , cord-035067-ic843wr9 95 27 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 95 28 symptoms symptom NNS cord-035067-ic843wr9 95 29 ( ( -LRB- cord-035067-ic843wr9 95 30 diarrhea diarrhea NN cord-035067-ic843wr9 95 31 , , , cord-035067-ic843wr9 95 32 nausea nausea NN cord-035067-ic843wr9 95 33 , , , cord-035067-ic843wr9 95 34 vomiting vomit VBG cord-035067-ic843wr9 95 35 , , , cord-035067-ic843wr9 95 36 and and CC cord-035067-ic843wr9 95 37 abdominal abdominal JJ cord-035067-ic843wr9 95 38 pain pain NN cord-035067-ic843wr9 95 39 ) ) -RRB- cord-035067-ic843wr9 95 40 , , , cord-035067-ic843wr9 95 41 and and CC cord-035067-ic843wr9 95 42 the the DT cord-035067-ic843wr9 95 43 presence presence NN cord-035067-ic843wr9 95 44 of of IN cord-035067-ic843wr9 95 45 viral viral JJ cord-035067-ic843wr9 95 46 RNA RNA NNP cord-035067-ic843wr9 95 47 in in IN cord-035067-ic843wr9 95 48 feces fece NNS cord-035067-ic843wr9 95 49 , , , cord-035067-ic843wr9 95 50 when when WRB cord-035067-ic843wr9 95 51 cited cite VBN cord-035067-ic843wr9 95 52 , , , cord-035067-ic843wr9 95 53 were be VBD cord-035067-ic843wr9 95 54 included include VBN cord-035067-ic843wr9 95 55 in in IN cord-035067-ic843wr9 95 56 this this DT cord-035067-ic843wr9 95 57 study study NN cord-035067-ic843wr9 95 58 for for IN cord-035067-ic843wr9 95 59 analysis analysis NN cord-035067-ic843wr9 95 60 . . . cord-035067-ic843wr9 95 61 _SP cord-035067-ic843wr9 96 1 As as IN cord-035067-ic843wr9 96 2 to to IN cord-035067-ic843wr9 96 3 retrospective retrospective JJ cord-035067-ic843wr9 96 4 studies study NNS cord-035067-ic843wr9 96 5 , , , cord-035067-ic843wr9 96 6 three three CD cord-035067-ic843wr9 96 7 were be VBD cord-035067-ic843wr9 96 8 done do VBN cord-035067-ic843wr9 96 9 only only RB cord-035067-ic843wr9 96 10 with with IN cord-035067-ic843wr9 96 11 patients patient NNS cord-035067-ic843wr9 96 12 from from IN cord-035067-ic843wr9 96 13 the the DT cord-035067-ic843wr9 96 14 United United NNP cord-035067-ic843wr9 96 15 States States NNP cord-035067-ic843wr9 96 16 and and CC cord-035067-ic843wr9 96 17 six six CD cord-035067-ic843wr9 96 18 only only RB cord-035067-ic843wr9 96 19 from from IN cord-035067-ic843wr9 96 20 China China NNP cord-035067-ic843wr9 96 21 . . . cord-035067-ic843wr9 97 1 The the DT cord-035067-ic843wr9 97 2 systematic systematic JJ cord-035067-ic843wr9 97 3 review review NN cord-035067-ic843wr9 97 4 included include VBD cord-035067-ic843wr9 97 5 several several JJ cord-035067-ic843wr9 97 6 studies study NNS cord-035067-ic843wr9 97 7 carried carry VBN cord-035067-ic843wr9 97 8 out out RP cord-035067-ic843wr9 97 9 in in IN cord-035067-ic843wr9 97 10 China China NNP cord-035067-ic843wr9 97 11 . . . cord-035067-ic843wr9 98 1 As as IN cord-035067-ic843wr9 98 2 to to IN cord-035067-ic843wr9 98 3 the the DT cord-035067-ic843wr9 98 4 meta meta NNP cord-035067-ic843wr9 98 5 - - HYPH cord-035067-ic843wr9 98 6 analyses analysis NNS cord-035067-ic843wr9 98 7 , , , cord-035067-ic843wr9 98 8 two two CD cord-035067-ic843wr9 98 9 of of IN cord-035067-ic843wr9 98 10 them -PRON- PRP cord-035067-ic843wr9 98 11 included include VBD cord-035067-ic843wr9 98 12 studies study NNS cord-035067-ic843wr9 98 13 done do VBN cord-035067-ic843wr9 98 14 only only RB cord-035067-ic843wr9 98 15 in in IN cord-035067-ic843wr9 98 16 China China NNP cord-035067-ic843wr9 98 17 and and CC cord-035067-ic843wr9 98 18 two two CD cord-035067-ic843wr9 98 19 evaluated evaluate VBD cord-035067-ic843wr9 98 20 various various JJ cord-035067-ic843wr9 98 21 countries country NNS cord-035067-ic843wr9 98 22 . . . cord-035067-ic843wr9 99 1 Tables table NNS cord-035067-ic843wr9 99 2 1 1 CD cord-035067-ic843wr9 99 3 to to IN cord-035067-ic843wr9 99 4 3 3 CD cord-035067-ic843wr9 99 5 present present JJ cord-035067-ic843wr9 99 6 general general JJ cord-035067-ic843wr9 99 7 data datum NNS cord-035067-ic843wr9 99 8 , , , cord-035067-ic843wr9 99 9 typical typical JJ cord-035067-ic843wr9 99 10 symptoms symptom NNS cord-035067-ic843wr9 99 11 , , , cord-035067-ic843wr9 99 12 and and CC cord-035067-ic843wr9 99 13 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 99 14 symptoms symptom NNS cord-035067-ic843wr9 99 15 of of IN cord-035067-ic843wr9 99 16 patients patient NNS cord-035067-ic843wr9 99 17 with with IN cord-035067-ic843wr9 99 18 COVID-19 covid-19 CD cord-035067-ic843wr9 99 19 of of IN cord-035067-ic843wr9 99 20 the the DT cord-035067-ic843wr9 99 21 retrospective retrospective JJ cord-035067-ic843wr9 99 22 studies study NNS cord-035067-ic843wr9 99 23 , , , cord-035067-ic843wr9 99 24 respectively respectively RB cord-035067-ic843wr9 99 25 . . . cord-035067-ic843wr9 100 1 Table table NN cord-035067-ic843wr9 100 2 4 4 CD cord-035067-ic843wr9 100 3 displays display VBZ cord-035067-ic843wr9 100 4 the the DT cord-035067-ic843wr9 100 5 symptoms symptom NNS cord-035067-ic843wr9 100 6 of of IN cord-035067-ic843wr9 100 7 patients patient NNS cord-035067-ic843wr9 100 8 with with IN cord-035067-ic843wr9 100 9 the the DT cord-035067-ic843wr9 100 10 disease disease NN cord-035067-ic843wr9 100 11 in in IN cord-035067-ic843wr9 100 12 the the DT cord-035067-ic843wr9 100 13 meta meta NNP cord-035067-ic843wr9 100 14 - - HYPH cord-035067-ic843wr9 100 15 analyses analysis NNS cord-035067-ic843wr9 100 16 . . . cord-035067-ic843wr9 101 1 einstein einstein NNP cord-035067-ic843wr9 101 2 ( ( -LRB- cord-035067-ic843wr9 101 3 São São NNP cord-035067-ic843wr9 101 4 Paulo Paulo NNP cord-035067-ic843wr9 101 5 ) ) -RRB- cord-035067-ic843wr9 101 6 . . . cord-035067-ic843wr9 102 1 2020;18:1 2020;18:1 CD cord-035067-ic843wr9 102 2 - - SYM cord-035067-ic843wr9 102 3 14 14 CD cord-035067-ic843wr9 102 4 Table Table NNP cord-035067-ic843wr9 102 5 1 1 CD cord-035067-ic843wr9 102 6 . . . cord-035067-ic843wr9 103 1 General general JJ cord-035067-ic843wr9 103 2 data datum NNS cord-035067-ic843wr9 103 3 of of IN cord-035067-ic843wr9 103 4 patients patient NNS cord-035067-ic843wr9 103 5 with with IN cord-035067-ic843wr9 103 6 COVID-19 covid-19 CD cord-035067-ic843wr9 103 7 of of IN cord-035067-ic843wr9 103 8 the the DT cord-035067-ic843wr9 103 9 nine nine CD cord-035067-ic843wr9 103 10 retrospective retrospective JJ cord-035067-ic843wr9 103 11 studies study NNS cord-035067-ic843wr9 103 12 Jin Jin NNP cord-035067-ic843wr9 103 13 et et NNP cord-035067-ic843wr9 103 14 al al NNP cord-035067-ic843wr9 103 15 . . . cord-035067-ic843wr9 104 1 ( ( -LRB- cord-035067-ic843wr9 104 2 18 18 CD cord-035067-ic843wr9 104 3 ) ) -RRB- cord-035067-ic843wr9 105 1 Lin Lin NNP cord-035067-ic843wr9 105 2 et et NNP cord-035067-ic843wr9 105 3 al al NNP cord-035067-ic843wr9 105 4 . . . cord-035067-ic843wr9 106 1 ( ( -LRB- cord-035067-ic843wr9 106 2 19 19 CD cord-035067-ic843wr9 106 3 ) ) -RRB- cord-035067-ic843wr9 106 4 Pan Pan NNP cord-035067-ic843wr9 106 5 et et NNP cord-035067-ic843wr9 106 6 al al NNP cord-035067-ic843wr9 106 7 . . . cord-035067-ic843wr9 107 1 ( ( -LRB- cord-035067-ic843wr9 107 2 20 20 CD cord-035067-ic843wr9 107 3 ) ) -RRB- cord-035067-ic843wr9 107 4 With with IN cord-035067-ic843wr9 107 5 GI GI NNP cord-035067-ic843wr9 107 6 symptoms symptom NNS cord-035067-ic843wr9 107 7 Lin Lin NNP cord-035067-ic843wr9 107 8 et et NNP cord-035067-ic843wr9 107 9 al al NNP cord-035067-ic843wr9 107 10 . . . cord-035067-ic843wr9 108 1 ( ( -LRB- cord-035067-ic843wr9 108 2 19 19 CD cord-035067-ic843wr9 108 3 ) ) -RRB- cord-035067-ic843wr9 108 4 Pan Pan NNP cord-035067-ic843wr9 108 5 L L NNP cord-035067-ic843wr9 108 6 et et NNP cord-035067-ic843wr9 108 7 al al NNP cord-035067-ic843wr9 108 8 . . . cord-035067-ic843wr9 109 1 ( ( -LRB- cord-035067-ic843wr9 109 2 20 20 CD cord-035067-ic843wr9 109 3 ) ) -RRB- cord-035067-ic843wr9 110 1 Wan Wan NNP cord-035067-ic843wr9 110 2 et et NNP cord-035067-ic843wr9 110 3 al al NNP cord-035067-ic843wr9 110 4 . . . cord-035067-ic843wr9 111 1 ( ( -LRB- cord-035067-ic843wr9 111 2 21 21 CD cord-035067-ic843wr9 111 3 ) ) -RRB- cord-035067-ic843wr9 112 1 Redd Redd NNP cord-035067-ic843wr9 112 2 et et NNP cord-035067-ic843wr9 112 3 al al NNP cord-035067-ic843wr9 112 4 . . . cord-035067-ic843wr9 113 1 ( ( -LRB- cord-035067-ic843wr9 113 2 22 22 CD cord-035067-ic843wr9 113 3 ) ) -RRB- cord-035067-ic843wr9 114 1 Nobel Nobel NNP cord-035067-ic843wr9 114 2 et et NNP cord-035067-ic843wr9 114 3 al al NNP cord-035067-ic843wr9 114 4 . . . cord-035067-ic843wr9 115 1 ( ( -LRB- cord-035067-ic843wr9 115 2 23 23 CD cord-035067-ic843wr9 115 3 ) ) -RRB- cord-035067-ic843wr9 116 1 Cholankeril Cholankeril NNP cord-035067-ic843wr9 116 2 et et NNP cord-035067-ic843wr9 116 3 al al NNP cord-035067-ic843wr9 116 4 . . . cord-035067-ic843wr9 117 1 ( ( -LRB- cord-035067-ic843wr9 117 2 24 24 CD cord-035067-ic843wr9 117 3 ) ) -RRB- cord-035067-ic843wr9 118 1 Zhang Zhang NNP cord-035067-ic843wr9 118 2 et et NNP cord-035067-ic843wr9 118 3 al al NNP cord-035067-ic843wr9 118 4 . . . cord-035067-ic843wr9 119 1 ( ( -LRB- cord-035067-ic843wr9 119 2 25 25 CD cord-035067-ic843wr9 119 3 ) ) -RRB- cord-035067-ic843wr9 120 1 Zhou Zhou NNP cord-035067-ic843wr9 120 2 et et NNP cord-035067-ic843wr9 120 3 al al NNP cord-035067-ic843wr9 120 4 . . . cord-035067-ic843wr9 121 1 ( ( -LRB- cord-035067-ic843wr9 121 2 Because because IN cord-035067-ic843wr9 121 3 of of IN cord-035067-ic843wr9 121 4 the the DT cord-035067-ic843wr9 121 5 small small JJ cord-035067-ic843wr9 121 6 sample sample NN cord-035067-ic843wr9 121 7 , , , cord-035067-ic843wr9 121 8 they -PRON- PRP cord-035067-ic843wr9 121 9 did do VBD cord-035067-ic843wr9 121 10 not not RB cord-035067-ic843wr9 121 11 evaluate evaluate VB cord-035067-ic843wr9 121 12 the the DT cord-035067-ic843wr9 121 13 implications implication NNS cord-035067-ic843wr9 121 14 of of IN cord-035067-ic843wr9 121 15 oral oral JJ cord-035067-ic843wr9 121 16 - - HYPH cord-035067-ic843wr9 121 17 fecal fecal NN cord-035067-ic843wr9 121 18 transmission transmission NN cord-035067-ic843wr9 121 19 , , , cord-035067-ic843wr9 121 20 which which WDT cord-035067-ic843wr9 121 21 needs need VBZ cord-035067-ic843wr9 121 22 further further JJ cord-035067-ic843wr9 121 23 investigation investigation NN cord-035067-ic843wr9 121 24 . . . cord-035067-ic843wr9 122 1 It -PRON- PRP cord-035067-ic843wr9 122 2 is be VBZ cord-035067-ic843wr9 122 3 worth worth JJ cord-035067-ic843wr9 122 4 remembering remember VBG cord-035067-ic843wr9 122 5 , , , cord-035067-ic843wr9 122 6 however however RB cord-035067-ic843wr9 122 7 , , , cord-035067-ic843wr9 122 8 that that IN cord-035067-ic843wr9 122 9 this this DT cord-035067-ic843wr9 122 10 study study NN cord-035067-ic843wr9 122 11 had have VBD cord-035067-ic843wr9 122 12 some some DT cord-035067-ic843wr9 122 13 limitations limitation NNS cord-035067-ic843wr9 122 14 . . . cord-035067-ic843wr9 123 1 It -PRON- PRP cord-035067-ic843wr9 123 2 was be VBD cord-035067-ic843wr9 123 3 not not RB cord-035067-ic843wr9 123 4 a a DT cord-035067-ic843wr9 123 5 cohort cohort NN cord-035067-ic843wr9 123 6 and and CC cord-035067-ic843wr9 123 7 did do VBD cord-035067-ic843wr9 123 8 not not RB cord-035067-ic843wr9 123 9 identify identify VB cord-035067-ic843wr9 123 10 patients patient NNS cord-035067-ic843wr9 123 11 with with IN cord-035067-ic843wr9 123 12 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 123 13 symptoms symptom NNS cord-035067-ic843wr9 123 14 who who WP cord-035067-ic843wr9 123 15 did do VBD cord-035067-ic843wr9 123 16 not not RB cord-035067-ic843wr9 123 17 have have VB cord-035067-ic843wr9 123 18 the the DT cord-035067-ic843wr9 123 19 typical typical JJ cord-035067-ic843wr9 123 20 symptoms symptom NNS cord-035067-ic843wr9 123 21 of of IN cord-035067-ic843wr9 123 22 cough cough NN cord-035067-ic843wr9 123 23 and and CC cord-035067-ic843wr9 123 24 fever fever NN cord-035067-ic843wr9 123 25 . . . cord-035067-ic843wr9 124 1 ( ( -LRB- cord-035067-ic843wr9 124 2 18 18 CD cord-035067-ic843wr9 124 3 ) ) -RRB- cord-035067-ic843wr9 125 1 In in IN cord-035067-ic843wr9 125 2 stomach stomach NN cord-035067-ic843wr9 125 3 , , , cord-035067-ic843wr9 125 4 duodenum duodenum NN cord-035067-ic843wr9 125 5 , , , cord-035067-ic843wr9 125 6 and and CC cord-035067-ic843wr9 125 7 rectum rectum NN cord-035067-ic843wr9 125 8 of of IN cord-035067-ic843wr9 125 9 these these DT cord-035067-ic843wr9 125 10 patients patient NNS cord-035067-ic843wr9 125 11 . . . cord-035067-ic843wr9 126 1 Of of IN cord-035067-ic843wr9 126 2 the the DT cord-035067-ic843wr9 126 3 non non JJ cord-035067-ic843wr9 126 4 - - JJ cord-035067-ic843wr9 126 5 severe severe JJ cord-035067-ic843wr9 126 6 patients patient NNS cord-035067-ic843wr9 126 7 , , , cord-035067-ic843wr9 126 8 only only RB cord-035067-ic843wr9 126 9 one one CD cord-035067-ic843wr9 126 10 had have VBD cord-035067-ic843wr9 126 11 viral viral JJ cord-035067-ic843wr9 126 12 RNA RNA NNP cord-035067-ic843wr9 126 13 presente presente FW cord-035067-ic843wr9 126 14 in in IN cord-035067-ic843wr9 126 15 the the DT cord-035067-ic843wr9 126 16 duodenum duodenum NN cord-035067-ic843wr9 126 17 . . . cord-035067-ic843wr9 127 1 This this DT cord-035067-ic843wr9 127 2 study study NN cord-035067-ic843wr9 127 3 concluded conclude VBD cord-035067-ic843wr9 127 4 that that IN cord-035067-ic843wr9 127 5 GIT GIT NNP cord-035067-ic843wr9 127 6 can can MD cord-035067-ic843wr9 127 7 be be VB cord-035067-ic843wr9 127 8 a a DT cord-035067-ic843wr9 127 9 potential potential JJ cord-035067-ic843wr9 127 10 transmission transmission NN cord-035067-ic843wr9 127 11 route route NN cord-035067-ic843wr9 127 12 and and CC cord-035067-ic843wr9 127 13 target target VB cord-035067-ic843wr9 127 14 organ organ NN cord-035067-ic843wr9 127 15 for for IN cord-035067-ic843wr9 127 16 SARS SARS NNP cord-035067-ic843wr9 127 17 - - HYPH cord-035067-ic843wr9 127 18 CoV-2 CoV-2 NNP cord-035067-ic843wr9 127 19 , , , cord-035067-ic843wr9 127 20 and and CC cord-035067-ic843wr9 127 21 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 127 22 symptoms symptom NNS cord-035067-ic843wr9 127 23 can can MD cord-035067-ic843wr9 127 24 not not RB cord-035067-ic843wr9 127 25 be be VB cord-035067-ic843wr9 127 26 underestimated underestimate VBN cord-035067-ic843wr9 127 27 . . . cord-035067-ic843wr9 128 1 ( ( -LRB- cord-035067-ic843wr9 128 2 19 19 CD cord-035067-ic843wr9 128 3 ) ) -RRB- cord-035067-ic843wr9 129 1 According accord VBG cord-035067-ic843wr9 129 2 to to IN cord-035067-ic843wr9 129 3 the the DT cord-035067-ic843wr9 129 4 descriptive descriptive JJ cord-035067-ic843wr9 129 5 , , , cord-035067-ic843wr9 129 6 cross cross JJ cord-035067-ic843wr9 129 7 - - JJ cord-035067-ic843wr9 129 8 sectional sectional JJ cord-035067-ic843wr9 129 9 , , , cord-035067-ic843wr9 129 10 multicenter multicenter JJ cord-035067-ic843wr9 129 11 study study NN cord-035067-ic843wr9 129 12 ( ( -LRB- cord-035067-ic843wr9 129 13 three three CD cord-035067-ic843wr9 129 14 hospitals hospital NNS cord-035067-ic843wr9 129 15 in in IN cord-035067-ic843wr9 129 16 Hubei Hubei NNP cord-035067-ic843wr9 129 17 , , , cord-035067-ic843wr9 129 18 China China NNP cord-035067-ic843wr9 129 19 ) ) -RRB- cord-035067-ic843wr9 129 20 by by IN cord-035067-ic843wr9 129 21 Pan Pan NNP cord-035067-ic843wr9 129 22 et et NNP cord-035067-ic843wr9 129 23 al al NNP cord-035067-ic843wr9 129 24 . . NNP cord-035067-ic843wr9 129 25 , , , cord-035067-ic843wr9 129 26 with with IN cord-035067-ic843wr9 129 27 204 204 CD cord-035067-ic843wr9 129 28 patients patient NNS cord-035067-ic843wr9 129 29 , , , cord-035067-ic843wr9 129 30 in in IN cord-035067-ic843wr9 129 31 which which WDT cord-035067-ic843wr9 129 32 107 107 CD cord-035067-ic843wr9 129 33 were be VBD cord-035067-ic843wr9 129 34 male male JJ cord-035067-ic843wr9 129 35 , , , cord-035067-ic843wr9 129 36 mean mean JJ cord-035067-ic843wr9 129 37 age age NN cord-035067-ic843wr9 129 38 of of IN cord-035067-ic843wr9 129 39 52.91±15.98 52.91±15.98 CD cord-035067-ic843wr9 129 40 years year NNS cord-035067-ic843wr9 129 41 , , , cord-035067-ic843wr9 129 42 103 103 CD cord-035067-ic843wr9 129 43 ( ( -LRB- cord-035067-ic843wr9 129 44 50.5 50.5 CD cord-035067-ic843wr9 129 45 % % NN cord-035067-ic843wr9 129 46 ) ) -RRB- cord-035067-ic843wr9 129 47 reported report VBD cord-035067-ic843wr9 129 48 some some DT cord-035067-ic843wr9 129 49 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 129 50 symptom symptom NN cord-035067-ic843wr9 129 51 , , , cord-035067-ic843wr9 129 52 such such JJ cord-035067-ic843wr9 129 53 as as IN cord-035067-ic843wr9 129 54 lack lack NN cord-035067-ic843wr9 129 55 of of IN cord-035067-ic843wr9 129 56 appetite appetite NN cord-035067-ic843wr9 129 57 ( ( -LRB- cord-035067-ic843wr9 129 58 81 81 CD cord-035067-ic843wr9 129 59 ; ; : cord-035067-ic843wr9 129 60 78.6 78.6 CD cord-035067-ic843wr9 129 61 % % NN cord-035067-ic843wr9 129 62 ) ) -RRB- cord-035067-ic843wr9 129 63 , , , cord-035067-ic843wr9 129 64 diarrhea diarrhea NN cord-035067-ic843wr9 129 65 ( ( -LRB- cord-035067-ic843wr9 129 66 35 35 CD cord-035067-ic843wr9 129 67 ; ; : cord-035067-ic843wr9 129 68 34.0 34.0 CD cord-035067-ic843wr9 129 69 % % NN cord-035067-ic843wr9 129 70 ) ) -RRB- cord-035067-ic843wr9 129 71 , , , cord-035067-ic843wr9 129 72 vomiting vomit VBG cord-035067-ic843wr9 129 73 ( ( -LRB- cord-035067-ic843wr9 129 74 4 4 CD cord-035067-ic843wr9 129 75 ; ; : cord-035067-ic843wr9 129 76 3.9 3.9 CD cord-035067-ic843wr9 129 77 % % NN cord-035067-ic843wr9 129 78 ) ) -RRB- cord-035067-ic843wr9 129 79 , , , cord-035067-ic843wr9 129 80 and and CC cord-035067-ic843wr9 129 81 abdominal abdominal JJ cord-035067-ic843wr9 129 82 pain pain NN cord-035067-ic843wr9 129 83 ( ( -LRB- cord-035067-ic843wr9 129 84 2 2 CD cord-035067-ic843wr9 129 85 ; ; : cord-035067-ic843wr9 129 86 1.9 1.9 CD cord-035067-ic843wr9 129 87 % % NN cord-035067-ic843wr9 129 88 ) ) -RRB- cord-035067-ic843wr9 129 89 . . . cord-035067-ic843wr9 130 1 If if IN cord-035067-ic843wr9 130 2 we -PRON- PRP cord-035067-ic843wr9 130 3 eliminate eliminate VBP cord-035067-ic843wr9 130 4 the the DT cord-035067-ic843wr9 130 5 lack lack NN cord-035067-ic843wr9 130 6 of of IN cord-035067-ic843wr9 130 7 appetite appetite NN cord-035067-ic843wr9 130 8 , , , cord-035067-ic843wr9 130 9 there there EX cord-035067-ic843wr9 130 10 were be VBD cord-035067-ic843wr9 130 11 38 38 CD cord-035067-ic843wr9 130 12 ( ( -LRB- cord-035067-ic843wr9 130 13 18.6 18.6 CD cord-035067-ic843wr9 130 14 % % NN cord-035067-ic843wr9 130 15 ) ) -RRB- cord-035067-ic843wr9 130 16 patients patient NNS cord-035067-ic843wr9 130 17 with with IN cord-035067-ic843wr9 130 18 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 130 19 symptoms symptom NNS cord-035067-ic843wr9 130 20 . . . cord-035067-ic843wr9 131 1 Six six CD cord-035067-ic843wr9 131 2 patients patient NNS cord-035067-ic843wr9 131 3 ( ( -LRB- cord-035067-ic843wr9 131 4 3 3 CD cord-035067-ic843wr9 131 5 % % NN cord-035067-ic843wr9 131 6 ) ) -RRB- cord-035067-ic843wr9 131 7 reported report VBD cord-035067-ic843wr9 131 8 only only JJ cord-035067-ic843wr9 131 9 digestive digestive JJ cord-035067-ic843wr9 131 10 symptoms symptom NNS cord-035067-ic843wr9 131 11 . . . cord-035067-ic843wr9 132 1 It -PRON- PRP cord-035067-ic843wr9 132 2 was be VBD cord-035067-ic843wr9 132 3 noted note VBN cord-035067-ic843wr9 132 4 that that IN cord-035067-ic843wr9 132 5 with with IN cord-035067-ic843wr9 132 6 increased increase VBN cord-035067-ic843wr9 132 7 severity severity NN cord-035067-ic843wr9 132 8 of of IN cord-035067-ic843wr9 132 9 the the DT cord-035067-ic843wr9 132 10 disease disease NN cord-035067-ic843wr9 132 11 , , , cord-035067-ic843wr9 132 12 the the DT cord-035067-ic843wr9 132 13 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 132 14 symptoms symptom NNS cord-035067-ic843wr9 132 15 became become VBD cord-035067-ic843wr9 132 16 more more RBR cord-035067-ic843wr9 132 17 pronounced pronounced JJ cord-035067-ic843wr9 132 18 . . . cord-035067-ic843wr9 133 1 Patients patient NNS cord-035067-ic843wr9 133 2 with with IN cord-035067-ic843wr9 133 3 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 133 4 symptoms symptom NNS cord-035067-ic843wr9 133 5 had have VBD cord-035067-ic843wr9 133 6 more more JJR cord-035067-ic843wr9 133 7 laboratory laboratory NN cord-035067-ic843wr9 133 8 abnormalities abnormality NNS cord-035067-ic843wr9 133 9 , , , cord-035067-ic843wr9 133 10 such such JJ cord-035067-ic843wr9 133 11 as as IN cord-035067-ic843wr9 133 12 elevation elevation NN cord-035067-ic843wr9 133 13 of of IN cord-035067-ic843wr9 133 14 alanine alanine NNP cord-035067-ic843wr9 133 15 aminotransferase aminotransferase NN cord-035067-ic843wr9 133 16 ( ( -LRB- cord-035067-ic843wr9 133 17 ALT ALT NNP cord-035067-ic843wr9 133 18 ; ; : cord-035067-ic843wr9 133 19 42.24U 42.24u CD cord-035067-ic843wr9 133 20 / / SYM cord-035067-ic843wr9 133 21 L l NN cord-035067-ic843wr9 133 22 versus versus IN cord-035067-ic843wr9 133 23 29.53U 29.53u CD cord-035067-ic843wr9 133 24 / / SYM cord-035067-ic843wr9 133 25 L l NN cord-035067-ic843wr9 133 26 ; ; : cord-035067-ic843wr9 133 27 p=0.011 p=0.011 NNP cord-035067-ic843wr9 133 28 ) ) -RRB- cord-035067-ic843wr9 133 29 and and CC cord-035067-ic843wr9 133 30 AST AST NNP cord-035067-ic843wr9 133 31 ( ( -LRB- cord-035067-ic843wr9 133 32 35.12U 35.12u CD cord-035067-ic843wr9 133 33 / / SYM cord-035067-ic843wr9 133 34 L l NN cord-035067-ic843wr9 133 35 versus versus IN cord-035067-ic843wr9 133 36 27.48U 27.48u CD cord-035067-ic843wr9 133 37 / / SYM cord-035067-ic843wr9 133 38 L l NN cord-035067-ic843wr9 133 39 ; ; : cord-035067-ic843wr9 134 1 p=0.032 p=0.032 NNP cord-035067-ic843wr9 134 2 ) ) -RRB- cord-035067-ic843wr9 134 3 , , , cord-035067-ic843wr9 134 4 decrease decrease NN cord-035067-ic843wr9 134 5 in in IN cord-035067-ic843wr9 134 6 monocyte monocyte NNP cord-035067-ic843wr9 134 7 count count NNP cord-035067-ic843wr9 134 8 ( ( -LRB- cord-035067-ic843wr9 134 9 0.39x10 0.39x10 CD cord-035067-ic843wr9 134 10 9 9 CD cord-035067-ic843wr9 134 11 /L /L . cord-035067-ic843wr9 134 12 versus versus IN cord-035067-ic843wr9 134 13 0.46x10 0.46x10 CD cord-035067-ic843wr9 134 14 9 9 CD cord-035067-ic843wr9 134 15 /L /L , cord-035067-ic843wr9 134 16 ) ) -RRB- cord-035067-ic843wr9 134 17 ; ; : cord-035067-ic843wr9 134 18 p=0.021 p=0.021 NNP cord-035067-ic843wr9 134 19 ) ) -RRB- cord-035067-ic843wr9 134 20 , , , cord-035067-ic843wr9 134 21 increased increase VBN cord-035067-ic843wr9 134 22 prothrombin prothrombin NN cord-035067-ic843wr9 134 23 time time NN cord-035067-ic843wr9 134 24 ( ( -LRB- cord-035067-ic843wr9 134 25 13.13 13.13 CD cord-035067-ic843wr9 134 26 seconds second NNS cord-035067-ic843wr9 134 27 versus versus IN cord-035067-ic843wr9 134 28 12.53 12.53 CD cord-035067-ic843wr9 134 29 seconds second NNS cord-035067-ic843wr9 134 30 ; ; : cord-035067-ic843wr9 134 31 p=0.024 p=0.024 NNP cord-035067-ic843wr9 134 32 ) ) -RRB- cord-035067-ic843wr9 134 33 , , , cord-035067-ic843wr9 134 34 and and CC cord-035067-ic843wr9 134 35 received receive VBD cord-035067-ic843wr9 134 36 more more JJR cord-035067-ic843wr9 134 37 antimicrobials antimicrobial NNS cord-035067-ic843wr9 134 38 during during IN cord-035067-ic843wr9 134 39 treatment treatment NN cord-035067-ic843wr9 134 40 ( ( -LRB- cord-035067-ic843wr9 134 41 76.70 76.70 CD cord-035067-ic843wr9 134 42 % % NN cord-035067-ic843wr9 134 43 versus versus IN cord-035067-ic843wr9 134 44 61.39 61.39 CD cord-035067-ic843wr9 134 45 % % NN cord-035067-ic843wr9 134 46 ; ; : cord-035067-ic843wr9 134 47 p=0.018 p=0.018 NNP cord-035067-ic843wr9 134 48 ) ) -RRB- cord-035067-ic843wr9 134 49 , , , cord-035067-ic843wr9 134 50 when when WRB cord-035067-ic843wr9 134 51 compared compare VBN cord-035067-ic843wr9 134 52 to to IN cord-035067-ic843wr9 134 53 those those DT cord-035067-ic843wr9 134 54 without without IN cord-035067-ic843wr9 134 55 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 134 56 symptoms symptom NNS cord-035067-ic843wr9 134 57 . . . cord-035067-ic843wr9 135 1 Thus thus RB cord-035067-ic843wr9 135 2 , , , cord-035067-ic843wr9 135 3 these these DT cord-035067-ic843wr9 135 4 patients patient NNS cord-035067-ic843wr9 135 5 had have VBD cord-035067-ic843wr9 135 6 a a DT cord-035067-ic843wr9 135 7 greater great JJR cord-035067-ic843wr9 135 8 chance chance NN cord-035067-ic843wr9 135 9 of of IN cord-035067-ic843wr9 135 10 suffering suffer VBG cord-035067-ic843wr9 135 11 hepatic hepatic JJ cord-035067-ic843wr9 135 12 injury injury NN cord-035067-ic843wr9 135 13 . . . cord-035067-ic843wr9 136 1 Yet yet RB cord-035067-ic843wr9 136 2 , , , cord-035067-ic843wr9 136 3 since since IN cord-035067-ic843wr9 136 4 this this DT cord-035067-ic843wr9 136 5 was be VBD cord-035067-ic843wr9 136 6 a a DT cord-035067-ic843wr9 136 7 retrospective retrospective JJ cord-035067-ic843wr9 136 8 study study NN cord-035067-ic843wr9 136 9 , , , cord-035067-ic843wr9 136 10 some some DT cord-035067-ic843wr9 136 11 limitations limitation NNS cord-035067-ic843wr9 136 12 should should MD cord-035067-ic843wr9 136 13 be be VB cord-035067-ic843wr9 136 14 considered consider VBN cord-035067-ic843wr9 136 15 , , , cord-035067-ic843wr9 136 16 such such JJ cord-035067-ic843wr9 136 17 as as IN cord-035067-ic843wr9 136 18 small small JJ cord-035067-ic843wr9 136 19 sample sample NN cord-035067-ic843wr9 136 20 and and CC cord-035067-ic843wr9 136 21 they -PRON- PRP cord-035067-ic843wr9 136 22 did do VBD cord-035067-ic843wr9 136 23 not not RB cord-035067-ic843wr9 136 24 test test VB cord-035067-ic843wr9 136 25 the the DT cord-035067-ic843wr9 136 26 presence presence NN cord-035067-ic843wr9 136 27 of of IN cord-035067-ic843wr9 136 28 SARS SARS NNP cord-035067-ic843wr9 136 29 - - HYPH cord-035067-ic843wr9 136 30 CoV-2 CoV-2 NNP cord-035067-ic843wr9 136 31 in in IN cord-035067-ic843wr9 136 32 the the DT cord-035067-ic843wr9 136 33 patients patient NNS cord-035067-ic843wr9 136 34 ' ' POS cord-035067-ic843wr9 136 35 feces fece NNS cord-035067-ic843wr9 136 36 . . . cord-035067-ic843wr9 137 1 ( ( -LRB- cord-035067-ic843wr9 137 2 20 20 CD cord-035067-ic843wr9 137 3 ) ) -RRB- cord-035067-ic843wr9 138 1 Wan Wan NNP cord-035067-ic843wr9 138 2 et et NNP cord-035067-ic843wr9 138 3 al al NNP cord-035067-ic843wr9 138 4 . . . cord-035067-ic843wr9 139 1 , , , cord-035067-ic843wr9 139 2 conducted conduct VBD cord-035067-ic843wr9 139 3 a a DT cord-035067-ic843wr9 139 4 multicenter multicenter JJ cord-035067-ic843wr9 139 5 retrospective retrospective JJ cord-035067-ic843wr9 139 6 study study NN cord-035067-ic843wr9 139 7 with with IN cord-035067-ic843wr9 139 8 14 14 CD cord-035067-ic843wr9 139 9 hospitals hospital NNS cord-035067-ic843wr9 139 10 in in IN cord-035067-ic843wr9 139 11 China China NNP cord-035067-ic843wr9 139 12 and and CC cord-035067-ic843wr9 139 13 showed show VBD cord-035067-ic843wr9 139 14 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 139 15 symptoms symptom NNS cord-035067-ic843wr9 139 16 are be VBP cord-035067-ic843wr9 139 17 common common JJ cord-035067-ic843wr9 139 18 in in IN cord-035067-ic843wr9 139 19 patients patient NNS cord-035067-ic843wr9 139 20 with with IN cord-035067-ic843wr9 139 21 COVID-19 COVID-19 NNP cord-035067-ic843wr9 139 22 . . . cord-035067-ic843wr9 140 1 Of of IN cord-035067-ic843wr9 140 2 230 230 CD cord-035067-ic843wr9 140 3 patients patient NNS cord-035067-ic843wr9 140 4 with with IN cord-035067-ic843wr9 140 5 the the DT cord-035067-ic843wr9 140 6 disease disease NN cord-035067-ic843wr9 140 7 , , , cord-035067-ic843wr9 140 8 129 129 CD cord-035067-ic843wr9 140 9 were be VBD cord-035067-ic843wr9 140 10 men man NNS cord-035067-ic843wr9 140 11 , , , cord-035067-ic843wr9 140 12 mean mean VB cord-035067-ic843wr9 140 13 age age NN cord-035067-ic843wr9 140 14 of of IN cord-035067-ic843wr9 140 15 47.5 47.5 CD cord-035067-ic843wr9 140 16 years year NNS cord-035067-ic843wr9 140 17 , , , cord-035067-ic843wr9 140 18 and and CC cord-035067-ic843wr9 140 19 diarrhea diarrhea NN cord-035067-ic843wr9 140 20 was be VBD cord-035067-ic843wr9 140 21 observed observe VBN cord-035067-ic843wr9 140 22 in in IN cord-035067-ic843wr9 140 23 49 49 CD cord-035067-ic843wr9 140 24 ( ( -LRB- cord-035067-ic843wr9 140 25 21 21 CD cord-035067-ic843wr9 140 26 % % NN cord-035067-ic843wr9 140 27 ) ) -RRB- cord-035067-ic843wr9 140 28 of of IN cord-035067-ic843wr9 140 29 them -PRON- PRP cord-035067-ic843wr9 140 30 . . . cord-035067-ic843wr9 141 1 Other other JJ cord-035067-ic843wr9 141 2 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 141 3 symptoms symptom NNS cord-035067-ic843wr9 141 4 , , , cord-035067-ic843wr9 141 5 such such JJ cord-035067-ic843wr9 141 6 as as IN cord-035067-ic843wr9 141 7 abdominal abdominal JJ cord-035067-ic843wr9 141 8 pain pain NN cord-035067-ic843wr9 141 9 ( ( -LRB- cord-035067-ic843wr9 141 10 3.1 3.1 CD cord-035067-ic843wr9 141 11 % % NN cord-035067-ic843wr9 141 12 ) ) -RRB- cord-035067-ic843wr9 141 13 and and CC cord-035067-ic843wr9 141 14 melena melena FW cord-035067-ic843wr9 141 15 ( ( -LRB- cord-035067-ic843wr9 141 16 10.4 10.4 CD cord-035067-ic843wr9 141 17 % % NN cord-035067-ic843wr9 141 18 ) ) -RRB- cord-035067-ic843wr9 141 19 , , , cord-035067-ic843wr9 141 20 were be VBD cord-035067-ic843wr9 141 21 also also RB cord-035067-ic843wr9 141 22 reported report VBN cord-035067-ic843wr9 141 23 . . . cord-035067-ic843wr9 142 1 The the DT cord-035067-ic843wr9 142 2 patients patient NNS cord-035067-ic843wr9 142 3 with with IN cord-035067-ic843wr9 142 4 diarrhea diarrhea NN cord-035067-ic843wr9 142 5 had have VBD cord-035067-ic843wr9 142 6 more more JJR cord-035067-ic843wr9 142 7 comorbidities comorbiditie NNS cord-035067-ic843wr9 142 8 ( ( -LRB- cord-035067-ic843wr9 142 9 39 39 CD cord-035067-ic843wr9 142 10 % % NN cord-035067-ic843wr9 142 11 versus versus IN cord-035067-ic843wr9 142 12 22 22 CD cord-035067-ic843wr9 142 13 % % NN cord-035067-ic843wr9 142 14 ; ; : cord-035067-ic843wr9 142 15 p=0.017 p=0.017 NNS cord-035067-ic843wr9 142 16 ) ) -RRB- cord-035067-ic843wr9 142 17 , , , cord-035067-ic843wr9 142 18 more more RBR cord-035067-ic843wr9 142 19 advanced advanced JJ cord-035067-ic843wr9 142 20 age age NN cord-035067-ic843wr9 142 21 ( ( -LRB- cord-035067-ic843wr9 142 22 55 55 CD cord-035067-ic843wr9 142 23 years year NNS cord-035067-ic843wr9 142 24 versus versus IN cord-035067-ic843wr9 142 25 46 46 CD cord-035067-ic843wr9 142 26 years year NNS cord-035067-ic843wr9 142 27 ; ; : cord-035067-ic843wr9 142 28 p=0.017 p=0.017 NNS cord-035067-ic843wr9 142 29 ) ) -RRB- cord-035067-ic843wr9 142 30 , , , cord-035067-ic843wr9 142 31 and and CC cord-035067-ic843wr9 142 32 presented present VBN cord-035067-ic843wr9 142 33 with with IN cord-035067-ic843wr9 142 34 more more JJR cord-035067-ic843wr9 142 35 severe severe JJ cord-035067-ic843wr9 142 36 symptoms symptom NNS cord-035067-ic843wr9 142 37 of of IN cord-035067-ic843wr9 142 38 respiratory respiratory JJ cord-035067-ic843wr9 142 39 problems problem NNS cord-035067-ic843wr9 142 40 , , , cord-035067-ic843wr9 142 41 requiring require VBG cord-035067-ic843wr9 142 42 ICU ICU NNP cord-035067-ic843wr9 142 43 ( ( -LRB- cord-035067-ic843wr9 142 44 31 31 CD cord-035067-ic843wr9 142 45 % % NN cord-035067-ic843wr9 142 46 versus versus IN cord-035067-ic843wr9 142 47 11 11 CD cord-035067-ic843wr9 142 48 % % NN cord-035067-ic843wr9 142 49 ; ; : cord-035067-ic843wr9 142 50 p=0.0015 p=0.0015 NNP cord-035067-ic843wr9 142 51 ) ) -RRB- cord-035067-ic843wr9 142 52 , , , cord-035067-ic843wr9 142 53 mechanical mechanical JJ cord-035067-ic843wr9 142 54 ventilation ventilation NN cord-035067-ic843wr9 142 55 ( ( -LRB- cord-035067-ic843wr9 142 56 12 12 CD cord-035067-ic843wr9 142 57 % % NN cord-035067-ic843wr9 142 58 versus versus IN cord-035067-ic843wr9 142 59 2 2 CD cord-035067-ic843wr9 142 60 % % NN cord-035067-ic843wr9 142 61 ; ; : cord-035067-ic843wr9 142 62 p=0.0036 p=0.0036 NNP cord-035067-ic843wr9 142 63 ) ) -RRB- cord-035067-ic843wr9 142 64 , , , cord-035067-ic843wr9 142 65 and and CC cord-035067-ic843wr9 142 66 progressing progress VBG cord-035067-ic843wr9 142 67 to to IN cord-035067-ic843wr9 142 68 death death NN cord-035067-ic843wr9 142 69 ( ( -LRB- cord-035067-ic843wr9 142 70 8 8 CD cord-035067-ic843wr9 142 71 % % NN cord-035067-ic843wr9 142 72 versus versus IN cord-035067-ic843wr9 142 73 1 1 CD cord-035067-ic843wr9 142 74 % % NN cord-035067-ic843wr9 142 75 ; ; : cord-035067-ic843wr9 142 76 p=0.020 p=0.020 ADD cord-035067-ic843wr9 142 77 ) ) -RRB- cord-035067-ic843wr9 142 78 . . . cord-035067-ic843wr9 143 1 The the DT cord-035067-ic843wr9 143 2 study study NN cord-035067-ic843wr9 143 3 has have VBZ cord-035067-ic843wr9 143 4 no no DT cord-035067-ic843wr9 143 5 data data NN cord-035067-ic843wr9 143 6 on on IN cord-035067-ic843wr9 143 7 asymptomatic asymptomatic JJ cord-035067-ic843wr9 143 8 patients patient NNS cord-035067-ic843wr9 143 9 , , , cord-035067-ic843wr9 143 10 which which WDT cord-035067-ic843wr9 143 11 may may MD cord-035067-ic843wr9 143 12 overestimate overestimate VB cord-035067-ic843wr9 143 13 the the DT cord-035067-ic843wr9 143 14 prevalence prevalence NN cord-035067-ic843wr9 143 15 of of IN cord-035067-ic843wr9 143 16 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 143 17 symptoms symptom NNS cord-035067-ic843wr9 143 18 in in IN cord-035067-ic843wr9 143 19 COVID-19 COVID-19 NNP cord-035067-ic843wr9 143 20 . . . cord-035067-ic843wr9 144 1 ( ( -LRB- cord-035067-ic843wr9 144 2 21 21 CD cord-035067-ic843wr9 144 3 ) ) -RRB- cord-035067-ic843wr9 145 1 A a DT cord-035067-ic843wr9 145 2 cohort cohort NN cord-035067-ic843wr9 145 3 study study NN cord-035067-ic843wr9 145 4 by by IN cord-035067-ic843wr9 145 5 Redd Redd NNP cord-035067-ic843wr9 145 6 et et NNP cord-035067-ic843wr9 145 7 al al NNP cord-035067-ic843wr9 145 8 . . . cord-035067-ic843wr9 146 1 , , , cord-035067-ic843wr9 146 2 The the DT cord-035067-ic843wr9 146 3 limitations limitation NNS cord-035067-ic843wr9 146 4 of of IN cord-035067-ic843wr9 146 5 the the DT cord-035067-ic843wr9 146 6 study study NN cord-035067-ic843wr9 146 7 were be VBD cord-035067-ic843wr9 146 8 a a DT cord-035067-ic843wr9 146 9 retrospective retrospective JJ cord-035067-ic843wr9 146 10 design design NN cord-035067-ic843wr9 146 11 , , , cord-035067-ic843wr9 146 12 lack lack NN cord-035067-ic843wr9 146 13 of of IN cord-035067-ic843wr9 146 14 instruments instrument NNS cord-035067-ic843wr9 146 15 to to TO cord-035067-ic843wr9 146 16 validate validate VB cord-035067-ic843wr9 146 17 symptoms symptom NNS cord-035067-ic843wr9 146 18 , , , cord-035067-ic843wr9 146 19 focus focus VBP cord-035067-ic843wr9 146 20 only only RB cord-035067-ic843wr9 146 21 on on IN cord-035067-ic843wr9 146 22 hospital hospital NN cord-035067-ic843wr9 146 23 data datum NNS cord-035067-ic843wr9 146 24 , , , cord-035067-ic843wr9 146 25 and and CC cord-035067-ic843wr9 146 26 the the DT cord-035067-ic843wr9 146 27 fact fact NN cord-035067-ic843wr9 146 28 that that IN cord-035067-ic843wr9 146 29 outpatients outpatient NNS cord-035067-ic843wr9 146 30 with with IN cord-035067-ic843wr9 146 31 less less RBR cord-035067-ic843wr9 146 32 severe severe JJ cord-035067-ic843wr9 146 33 disease disease NN cord-035067-ic843wr9 146 34 were be VBD cord-035067-ic843wr9 146 35 excluded exclude VBN cord-035067-ic843wr9 146 36 . . . cord-035067-ic843wr9 147 1 In in IN cord-035067-ic843wr9 147 2 addition addition NN cord-035067-ic843wr9 147 3 , , , cord-035067-ic843wr9 147 4 the the DT cord-035067-ic843wr9 147 5 article article NN cord-035067-ic843wr9 147 6 did do VBD cord-035067-ic843wr9 147 7 not not RB cord-035067-ic843wr9 147 8 evaluate evaluate VB cord-035067-ic843wr9 147 9 the the DT cord-035067-ic843wr9 147 10 presence presence NN cord-035067-ic843wr9 147 11 of of IN cord-035067-ic843wr9 147 12 the the DT cord-035067-ic843wr9 147 13 virus virus NN cord-035067-ic843wr9 147 14 in in IN cord-035067-ic843wr9 147 15 the the DT cord-035067-ic843wr9 147 16 stool stool NN cord-035067-ic843wr9 147 17 of of IN cord-035067-ic843wr9 147 18 these these DT cord-035067-ic843wr9 147 19 patients patient NNS cord-035067-ic843wr9 147 20 . . . cord-035067-ic843wr9 148 1 ( ( -LRB- cord-035067-ic843wr9 148 2 22 22 CD cord-035067-ic843wr9 148 3 ) ) -RRB- cord-035067-ic843wr9 149 1 Nobel Nobel NNP cord-035067-ic843wr9 149 2 et et NNP cord-035067-ic843wr9 149 3 al al NNP cord-035067-ic843wr9 149 4 . . NNP cord-035067-ic843wr9 149 5 , , , cord-035067-ic843wr9 149 6 performed perform VBD cord-035067-ic843wr9 149 7 a a DT cord-035067-ic843wr9 149 8 retrospective retrospective JJ cord-035067-ic843wr9 149 9 control control NN cord-035067-ic843wr9 149 10 case case NN cord-035067-ic843wr9 149 11 study study NN cord-035067-ic843wr9 149 12 that that IN cord-035067-ic843wr9 149 13 compared compare VBD cord-035067-ic843wr9 149 14 the the DT cord-035067-ic843wr9 149 15 symptoms symptom NNS cord-035067-ic843wr9 149 16 of of IN cord-035067-ic843wr9 149 17 278 278 CD cord-035067-ic843wr9 149 18 patients patient NNS cord-035067-ic843wr9 149 19 positive positive JJ cord-035067-ic843wr9 149 20 for for IN cord-035067-ic843wr9 149 21 SARS SARS NNP cord-035067-ic843wr9 149 22 - - HYPH cord-035067-ic843wr9 149 23 CoV-2 CoV-2 NNP cord-035067-ic843wr9 149 24 with with IN cord-035067-ic843wr9 149 25 238 238 CD cord-035067-ic843wr9 149 26 negative negative JJ cord-035067-ic843wr9 149 27 patients patient NNS cord-035067-ic843wr9 149 28 in in IN cord-035067-ic843wr9 149 29 the the DT cord-035067-ic843wr9 149 30 United United NNP cord-035067-ic843wr9 149 31 States States NNP cord-035067-ic843wr9 149 32 . . . cord-035067-ic843wr9 150 1 The the DT cord-035067-ic843wr9 150 2 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 150 3 symptoms symptom NNS cord-035067-ic843wr9 150 4 considered consider VBN cord-035067-ic843wr9 150 5 were be VBD cord-035067-ic843wr9 150 6 diarrhea diarrhea JJ cord-035067-ic843wr9 150 7 or or CC cord-035067-ic843wr9 150 8 nausea nausea NN cord-035067-ic843wr9 150 9 / / SYM cord-035067-ic843wr9 150 10 vomiting vomiting NN cord-035067-ic843wr9 150 11 . . . cord-035067-ic843wr9 151 1 They -PRON- PRP cord-035067-ic843wr9 151 2 found find VBD cord-035067-ic843wr9 151 3 a a DT cord-035067-ic843wr9 151 4 significant significant JJ cord-035067-ic843wr9 151 5 difference difference NN cord-035067-ic843wr9 151 6 between between IN cord-035067-ic843wr9 151 7 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 151 8 symptoms symptom NNS cord-035067-ic843wr9 151 9 in in IN cord-035067-ic843wr9 151 10 patients patient NNS cord-035067-ic843wr9 151 11 with with IN cord-035067-ic843wr9 151 12 and and CC cord-035067-ic843wr9 151 13 without without IN cord-035067-ic843wr9 151 14 COVID-19 COVID-19 NNP cord-035067-ic843wr9 151 15 ( ( -LRB- cord-035067-ic843wr9 151 16 p=0.04 p=0.04 NNP cord-035067-ic843wr9 151 17 ) ) -RRB- cord-035067-ic843wr9 151 18 . . . cord-035067-ic843wr9 152 1 The the DT cord-035067-ic843wr9 152 2 presence presence NN cord-035067-ic843wr9 152 3 of of IN cord-035067-ic843wr9 152 4 these these DT cord-035067-ic843wr9 152 5 symptoms symptom NNS cord-035067-ic843wr9 152 6 was be VBD cord-035067-ic843wr9 152 7 associated associate VBN cord-035067-ic843wr9 152 8 to to IN cord-035067-ic843wr9 152 9 a a DT cord-035067-ic843wr9 152 10 risk risk NN cord-035067-ic843wr9 152 11 greater great JJR cord-035067-ic843wr9 152 12 than than IN cord-035067-ic843wr9 152 13 70 70 CD cord-035067-ic843wr9 152 14 % % NN cord-035067-ic843wr9 152 15 of of IN cord-035067-ic843wr9 152 16 having have VBG cord-035067-ic843wr9 152 17 COVID-19 covid-19 CD cord-035067-ic843wr9 152 18 . . . cord-035067-ic843wr9 153 1 Among among IN cord-035067-ic843wr9 153 2 the the DT cord-035067-ic843wr9 153 3 COVID-19 COVID-19 NNP cord-035067-ic843wr9 153 4 patients patient NNS cord-035067-ic843wr9 153 5 , , , cord-035067-ic843wr9 153 6 97 97 CD cord-035067-ic843wr9 153 7 ( ( -LRB- cord-035067-ic843wr9 153 8 35 35 CD cord-035067-ic843wr9 153 9 % % NN cord-035067-ic843wr9 153 10 ) ) -RRB- cord-035067-ic843wr9 153 11 presented present VBN cord-035067-ic843wr9 153 12 with with IN cord-035067-ic843wr9 153 13 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 153 14 symptoms symptom NNS cord-035067-ic843wr9 153 15 , , , cord-035067-ic843wr9 153 16 such such JJ cord-035067-ic843wr9 153 17 as as IN cord-035067-ic843wr9 153 18 diarrhea diarrhea NN cord-035067-ic843wr9 153 19 ( ( -LRB- cord-035067-ic843wr9 153 20 56 56 CD cord-035067-ic843wr9 153 21 ; ; : cord-035067-ic843wr9 153 22 20 20 CD cord-035067-ic843wr9 153 23 % % NN cord-035067-ic843wr9 153 24 ) ) -RRB- cord-035067-ic843wr9 153 25 and and CC cord-035067-ic843wr9 153 26 nausea nausea NN cord-035067-ic843wr9 153 27 / / SYM cord-035067-ic843wr9 153 28 vomiting vomiting NN cord-035067-ic843wr9 153 29 ( ( -LRB- cord-035067-ic843wr9 153 30 63 63 CD cord-035067-ic843wr9 153 31 ; ; : cord-035067-ic843wr9 153 32 23 23 CD cord-035067-ic843wr9 153 33 % % NN cord-035067-ic843wr9 153 34 ) ) -RRB- cord-035067-ic843wr9 153 35 . . . cord-035067-ic843wr9 154 1 Patients patient NNS cord-035067-ic843wr9 154 2 with with IN cord-035067-ic843wr9 154 3 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 154 4 symptoms symptom NNS cord-035067-ic843wr9 154 5 had have VBD cord-035067-ic843wr9 154 6 a a DT cord-035067-ic843wr9 154 7 longer long JJR cord-035067-ic843wr9 154 8 duration duration NN cord-035067-ic843wr9 154 9 of of IN cord-035067-ic843wr9 154 10 the the DT cord-035067-ic843wr9 154 11 disease disease NN cord-035067-ic843wr9 154 12 when when WRB cord-035067-ic843wr9 154 13 compared compare VBN cord-035067-ic843wr9 154 14 to to IN cord-035067-ic843wr9 154 15 those those DT cord-035067-ic843wr9 154 16 without without IN cord-035067-ic843wr9 154 17 these these DT cord-035067-ic843wr9 154 18 symptoms symptom NNS cord-035067-ic843wr9 154 19 ( ( -LRB- cord-035067-ic843wr9 154 20 33 33 CD cord-035067-ic843wr9 154 21 % % NN cord-035067-ic843wr9 154 22 versus versus IN cord-035067-ic843wr9 154 23 22 22 CD cord-035067-ic843wr9 154 24 % % NN cord-035067-ic843wr9 154 25 ; ; : cord-035067-ic843wr9 154 26 p=0.048 p=0.048 NNP cord-035067-ic843wr9 154 27 ) ) -RRB- cord-035067-ic843wr9 154 28 . . . cord-035067-ic843wr9 155 1 The the DT cord-035067-ic843wr9 155 2 limitations limitation NNS cord-035067-ic843wr9 155 3 of of IN cord-035067-ic843wr9 155 4 the the DT cord-035067-ic843wr9 155 5 study study NN cord-035067-ic843wr9 155 6 were be VBD cord-035067-ic843wr9 155 7 a a DT cord-035067-ic843wr9 155 8 short short JJ cord-035067-ic843wr9 155 9 patient patient JJ cord-035067-ic843wr9 155 10 followup followup JJ cord-035067-ic843wr9 155 11 period period NN cord-035067-ic843wr9 155 12 , , , cord-035067-ic843wr9 155 13 a a DT cord-035067-ic843wr9 155 14 retrospective retrospective JJ cord-035067-ic843wr9 155 15 study study NN cord-035067-ic843wr9 155 16 , , , cord-035067-ic843wr9 155 17 and and CC cord-035067-ic843wr9 155 18 the the DT cord-035067-ic843wr9 155 19 identification identification NN cord-035067-ic843wr9 155 20 of of IN cord-035067-ic843wr9 155 21 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 155 22 symptoms symptom NNS cord-035067-ic843wr9 155 23 was be VBD cord-035067-ic843wr9 155 24 dependent dependent JJ cord-035067-ic843wr9 155 25 on on IN cord-035067-ic843wr9 155 26 documentation documentation NN cord-035067-ic843wr9 155 27 done do VBN cord-035067-ic843wr9 155 28 well well RB cord-035067-ic843wr9 155 29 . . . cord-035067-ic843wr9 156 1 This this DT cord-035067-ic843wr9 156 2 article article NN cord-035067-ic843wr9 156 3 also also RB cord-035067-ic843wr9 156 4 did do VBD cord-035067-ic843wr9 156 5 not not RB cord-035067-ic843wr9 156 6 evaluate evaluate VB cord-035067-ic843wr9 156 7 the the DT cord-035067-ic843wr9 156 8 presence presence NN cord-035067-ic843wr9 156 9 of of IN cord-035067-ic843wr9 156 10 the the DT cord-035067-ic843wr9 156 11 virus virus NN cord-035067-ic843wr9 156 12 in in IN cord-035067-ic843wr9 156 13 the the DT cord-035067-ic843wr9 156 14 feces fece NNS cord-035067-ic843wr9 156 15 of of IN cord-035067-ic843wr9 156 16 the the DT cord-035067-ic843wr9 156 17 patients patient NNS cord-035067-ic843wr9 156 18 . . . cord-035067-ic843wr9 157 1 ( ( -LRB- cord-035067-ic843wr9 157 2 23 23 CD cord-035067-ic843wr9 157 3 ) ) -RRB- cord-035067-ic843wr9 158 1 In in IN cord-035067-ic843wr9 158 2 a a DT cord-035067-ic843wr9 158 3 cohort cohort NN cord-035067-ic843wr9 158 4 study study NN cord-035067-ic843wr9 158 5 by by IN cord-035067-ic843wr9 158 6 Cholankeril Cholankeril NNP cord-035067-ic843wr9 158 7 et et NNP cord-035067-ic843wr9 158 8 al al NNP cord-035067-ic843wr9 158 9 . . NNP cord-035067-ic843wr9 158 10 , , , cord-035067-ic843wr9 158 11 116 116 CD cord-035067-ic843wr9 158 12 patients patient NNS cord-035067-ic843wr9 158 13 with with IN cord-035067-ic843wr9 158 14 COVID-19 COVID-19 NNP cord-035067-ic843wr9 158 15 , , , cord-035067-ic843wr9 158 16 most most JJS cord-035067-ic843wr9 158 17 of of IN cord-035067-ic843wr9 158 18 them -PRON- PRP cord-035067-ic843wr9 158 19 male male JJ cord-035067-ic843wr9 158 20 ( ( -LRB- cord-035067-ic843wr9 158 21 53.4 53.4 CD cord-035067-ic843wr9 158 22 % % NN cord-035067-ic843wr9 158 23 ) ) -RRB- cord-035067-ic843wr9 158 24 , , , cord-035067-ic843wr9 158 25 mean mean JJ cord-035067-ic843wr9 158 26 age age NN cord-035067-ic843wr9 158 27 of of IN cord-035067-ic843wr9 158 28 50 50 CD cord-035067-ic843wr9 158 29 years year NNS cord-035067-ic843wr9 158 30 . . . cord-035067-ic843wr9 159 1 No no DT cord-035067-ic843wr9 159 2 patient patient NN cord-035067-ic843wr9 159 3 presented present VBN cord-035067-ic843wr9 159 4 with with IN cord-035067-ic843wr9 159 5 isolated isolated JJ cord-035067-ic843wr9 159 6 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 159 7 symptoms symptom NNS cord-035067-ic843wr9 159 8 as as IN cord-035067-ic843wr9 159 9 the the DT cord-035067-ic843wr9 159 10 initial initial JJ cord-035067-ic843wr9 159 11 manifestation manifestation NN cord-035067-ic843wr9 159 12 . . . cord-035067-ic843wr9 160 1 The the DT cord-035067-ic843wr9 160 2 mean mean JJ cord-035067-ic843wr9 160 3 duration duration NN cord-035067-ic843wr9 160 4 of of IN cord-035067-ic843wr9 160 5 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 160 6 symptoms symptom NNS cord-035067-ic843wr9 160 7 was be VBD cord-035067-ic843wr9 160 8 one one CD cord-035067-ic843wr9 160 9 day day NN cord-035067-ic843wr9 160 10 , , , cord-035067-ic843wr9 160 11 which which WDT cord-035067-ic843wr9 160 12 was be VBD cord-035067-ic843wr9 160 13 significantly significantly RB cord-035067-ic843wr9 160 14 shorter short JJR cord-035067-ic843wr9 160 15 than than IN cord-035067-ic843wr9 160 16 the the DT cord-035067-ic843wr9 160 17 duration duration NN cord-035067-ic843wr9 160 18 of of IN cord-035067-ic843wr9 160 19 respiratory respiratory JJ cord-035067-ic843wr9 160 20 symptoms symptom NNS cord-035067-ic843wr9 160 21 ( ( -LRB- cord-035067-ic843wr9 160 22 p<0.001 p<0.001 CD cord-035067-ic843wr9 160 23 ) ) -RRB- cord-035067-ic843wr9 160 24 . . . cord-035067-ic843wr9 161 1 The the DT cord-035067-ic843wr9 161 2 elevation elevation NN cord-035067-ic843wr9 161 3 of of IN cord-035067-ic843wr9 161 4 AST AST NNP cord-035067-ic843wr9 161 5 correlated correlate VBD cord-035067-ic843wr9 161 6 with with IN cord-035067-ic843wr9 161 7 severity severity NN cord-035067-ic843wr9 161 8 of of IN cord-035067-ic843wr9 161 9 the the DT cord-035067-ic843wr9 161 10 disease disease NN cord-035067-ic843wr9 161 11 ( ( -LRB- cord-035067-ic843wr9 161 12 p=0.009 p=0.009 NN cord-035067-ic843wr9 161 13 ) ) -RRB- cord-035067-ic843wr9 161 14 . . . cord-035067-ic843wr9 162 1 This this DT cord-035067-ic843wr9 162 2 study study NN cord-035067-ic843wr9 162 3 presented present VBD cord-035067-ic843wr9 162 4 limitations limitation NNS cord-035067-ic843wr9 162 5 , , , cord-035067-ic843wr9 162 6 such such JJ cord-035067-ic843wr9 162 7 as as IN cord-035067-ic843wr9 162 8 patients patient NNS cord-035067-ic843wr9 162 9 from from IN cord-035067-ic843wr9 162 10 only only RB cord-035067-ic843wr9 162 11 one one CD cord-035067-ic843wr9 162 12 organization organization NN cord-035067-ic843wr9 162 13 ( ( -LRB- cord-035067-ic843wr9 162 14 regional regional JJ cord-035067-ic843wr9 162 15 trend trend NN cord-035067-ic843wr9 162 16 ) ) -RRB- cord-035067-ic843wr9 162 17 , , , cord-035067-ic843wr9 162 18 the the DT cord-035067-ic843wr9 162 19 fact fact NN cord-035067-ic843wr9 162 20 of of IN cord-035067-ic843wr9 162 21 documentation documentation NN cord-035067-ic843wr9 162 22 of of IN cord-035067-ic843wr9 162 23 extrapulmonary extrapulmonary JJ cord-035067-ic843wr9 162 24 symptoms symptom NNS cord-035067-ic843wr9 162 25 may may MD cord-035067-ic843wr9 162 26 be be VB cord-035067-ic843wr9 162 27 incomplete incomplete JJ cord-035067-ic843wr9 162 28 , , , cord-035067-ic843wr9 162 29 and and CC cord-035067-ic843wr9 162 30 the the DT cord-035067-ic843wr9 162 31 diagnosis diagnosis NN cord-035067-ic843wr9 162 32 of of IN cord-035067-ic843wr9 162 33 COVID-19 COVID-19 NNP cord-035067-ic843wr9 162 34 was be VBD cord-035067-ic843wr9 162 35 only only RB cord-035067-ic843wr9 162 36 done do VBN cord-035067-ic843wr9 162 37 in in IN cord-035067-ic843wr9 162 38 patients patient NNS cord-035067-ic843wr9 162 39 with with IN cord-035067-ic843wr9 162 40 respiratory respiratory JJ cord-035067-ic843wr9 162 41 symptoms symptom NNS cord-035067-ic843wr9 162 42 . . . cord-035067-ic843wr9 163 1 The the DT cord-035067-ic843wr9 163 2 article article NN cord-035067-ic843wr9 163 3 did do VBD cord-035067-ic843wr9 163 4 not not RB cord-035067-ic843wr9 163 5 evaluate evaluate VB cord-035067-ic843wr9 163 6 the the DT cord-035067-ic843wr9 163 7 presence presence NN cord-035067-ic843wr9 163 8 of of IN cord-035067-ic843wr9 163 9 the the DT cord-035067-ic843wr9 163 10 virus virus NN cord-035067-ic843wr9 163 11 in in IN cord-035067-ic843wr9 163 12 the the DT cord-035067-ic843wr9 163 13 feces fece NNS cord-035067-ic843wr9 163 14 of of IN cord-035067-ic843wr9 163 15 these these DT cord-035067-ic843wr9 163 16 patients patient NNS cord-035067-ic843wr9 163 17 . . . cord-035067-ic843wr9 164 1 ( ( -LRB- cord-035067-ic843wr9 164 2 24 24 CD cord-035067-ic843wr9 164 3 ) ) -RRB- cord-035067-ic843wr9 165 1 For for IN cord-035067-ic843wr9 165 2 Zhang Zhang NNP cord-035067-ic843wr9 165 3 et et NNP cord-035067-ic843wr9 165 4 al al NNP cord-035067-ic843wr9 165 5 . . NNP cord-035067-ic843wr9 165 6 , , , cord-035067-ic843wr9 165 7 who who WP cord-035067-ic843wr9 165 8 studied study VBD cord-035067-ic843wr9 165 9 in in IN cord-035067-ic843wr9 165 10 140 140 CD cord-035067-ic843wr9 165 11 patients patient NNS cord-035067-ic843wr9 165 12 from from IN cord-035067-ic843wr9 165 13 China China NNP cord-035067-ic843wr9 165 14 with with IN cord-035067-ic843wr9 165 15 COVID-19 COVID-19 NNP cord-035067-ic843wr9 165 16 , , , cord-035067-ic843wr9 165 17 39.6 39.6 CD cord-035067-ic843wr9 165 18 % % NN cord-035067-ic843wr9 165 19 of of IN cord-035067-ic843wr9 165 20 them -PRON- PRP cord-035067-ic843wr9 165 21 presented present VBN cord-035067-ic843wr9 165 22 with with IN cord-035067-ic843wr9 165 23 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 165 24 symptoms symptom NNS cord-035067-ic843wr9 165 25 . . . cord-035067-ic843wr9 166 1 In in IN cord-035067-ic843wr9 166 2 this this DT cord-035067-ic843wr9 166 3 study study NN cord-035067-ic843wr9 166 4 , , , cord-035067-ic843wr9 166 5 the the DT cord-035067-ic843wr9 166 6 proportion proportion NN cord-035067-ic843wr9 166 7 between between IN cord-035067-ic843wr9 166 8 men man NNS cord-035067-ic843wr9 166 9 and and CC cord-035067-ic843wr9 166 10 women woman NNS cord-035067-ic843wr9 166 11 was be VBD cord-035067-ic843wr9 166 12 practically practically RB cord-035067-ic843wr9 166 13 the the DT cord-035067-ic843wr9 166 14 same same JJ cord-035067-ic843wr9 166 15 , , , cord-035067-ic843wr9 166 16 and and CC cord-035067-ic843wr9 166 17 mean mean VB cord-035067-ic843wr9 166 18 age age NN cord-035067-ic843wr9 166 19 was be VBD cord-035067-ic843wr9 166 20 57.0 57.0 CD cord-035067-ic843wr9 166 21 years year NNS cord-035067-ic843wr9 166 22 . . . cord-035067-ic843wr9 167 1 The the DT cord-035067-ic843wr9 167 2 main main JJ cord-035067-ic843wr9 167 3 symptoms symptom NNS cord-035067-ic843wr9 167 4 were be VBD cord-035067-ic843wr9 167 5 fever fever NN cord-035067-ic843wr9 167 6 ( ( -LRB- cord-035067-ic843wr9 167 7 91.7 91.7 CD cord-035067-ic843wr9 167 8 % % NN cord-035067-ic843wr9 167 9 ) ) -RRB- cord-035067-ic843wr9 167 10 , , , cord-035067-ic843wr9 167 11 cough cough NN cord-035067-ic843wr9 167 12 ( ( -LRB- cord-035067-ic843wr9 167 13 75.0 75.0 CD cord-035067-ic843wr9 167 14 % % NN cord-035067-ic843wr9 167 15 ) ) -RRB- cord-035067-ic843wr9 167 16 , , , cord-035067-ic843wr9 167 17 and and CC cord-035067-ic843wr9 167 18 fatigue fatigue NN cord-035067-ic843wr9 167 19 ( ( -LRB- cord-035067-ic843wr9 167 20 75.0 75.0 CD cord-035067-ic843wr9 167 21 % % NN cord-035067-ic843wr9 167 22 ) ) -RRB- cord-035067-ic843wr9 167 23 . . . cord-035067-ic843wr9 168 1 They -PRON- PRP cord-035067-ic843wr9 168 2 point point VBP cord-035067-ic843wr9 168 3 out out RP cord-035067-ic843wr9 168 4 that that IN cord-035067-ic843wr9 168 5 eosinopenia eosinopenia NNP cord-035067-ic843wr9 168 6 , , , cord-035067-ic843wr9 168 7 with with IN cord-035067-ic843wr9 168 8 or or CC cord-035067-ic843wr9 168 9 without without IN cord-035067-ic843wr9 168 10 lymphopenia lymphopenia NNP cord-035067-ic843wr9 168 11 in in IN cord-035067-ic843wr9 168 12 patients patient NNS cord-035067-ic843wr9 168 13 with with IN cord-035067-ic843wr9 168 14 symptoms symptom NNS cord-035067-ic843wr9 168 15 and and CC cord-035067-ic843wr9 168 16 radiological radiological JJ cord-035067-ic843wr9 168 17 changes change NNS cord-035067-ic843wr9 168 18 , , , cord-035067-ic843wr9 168 19 may may MD cord-035067-ic843wr9 168 20 be be VB cord-035067-ic843wr9 168 21 a a DT cord-035067-ic843wr9 168 22 potential potential JJ cord-035067-ic843wr9 168 23 indicator indicator NN cord-035067-ic843wr9 168 24 for for IN cord-035067-ic843wr9 168 25 the the DT cord-035067-ic843wr9 168 26 diagnosis diagnosis NN cord-035067-ic843wr9 168 27 of of IN cord-035067-ic843wr9 168 28 COVID-19 COVID-19 NNP cord-035067-ic843wr9 168 29 . . . cord-035067-ic843wr9 169 1 In in IN cord-035067-ic843wr9 169 2 addition addition NN cord-035067-ic843wr9 169 3 , , , cord-035067-ic843wr9 169 4 they -PRON- PRP cord-035067-ic843wr9 169 5 found find VBD cord-035067-ic843wr9 169 6 that that IN cord-035067-ic843wr9 169 7 allergic allergic JJ cord-035067-ic843wr9 169 8 diseases disease NNS cord-035067-ic843wr9 169 9 , , , cord-035067-ic843wr9 169 10 asthma asthma NN cord-035067-ic843wr9 169 11 , , , cord-035067-ic843wr9 169 12 and and CC cord-035067-ic843wr9 169 13 chronic chronic JJ cord-035067-ic843wr9 169 14 obstructive obstructive JJ cord-035067-ic843wr9 169 15 pulmonary pulmonary JJ cord-035067-ic843wr9 169 16 disease disease NN cord-035067-ic843wr9 169 17 ( ( -LRB- cord-035067-ic843wr9 169 18 COPD COPD NNP cord-035067-ic843wr9 169 19 ) ) -RRB- cord-035067-ic843wr9 169 20 are be VBP cord-035067-ic843wr9 169 21 not not RB cord-035067-ic843wr9 169 22 risk risk NN cord-035067-ic843wr9 169 23 factors factor NNS cord-035067-ic843wr9 169 24 for for IN cord-035067-ic843wr9 169 25 SARS SARS NNP cord-035067-ic843wr9 169 26 - - HYPH cord-035067-ic843wr9 169 27 CoV-2 CoV-2 NNP cord-035067-ic843wr9 169 28 infection infection NN cord-035067-ic843wr9 169 29 , , , cord-035067-ic843wr9 169 30 but but CC cord-035067-ic843wr9 169 31 studies study NNS cord-035067-ic843wr9 169 32 with with IN cord-035067-ic843wr9 169 33 larger large JJR cord-035067-ic843wr9 169 34 samples sample NNS cord-035067-ic843wr9 169 35 are be VBP cord-035067-ic843wr9 169 36 needed need VBN cord-035067-ic843wr9 169 37 to to TO cord-035067-ic843wr9 169 38 confirm confirm VB cord-035067-ic843wr9 169 39 these these DT cord-035067-ic843wr9 169 40 findings finding NNS cord-035067-ic843wr9 169 41 . . . cord-035067-ic843wr9 170 1 Advanced advanced JJ cord-035067-ic843wr9 170 2 age age NN cord-035067-ic843wr9 170 3 ( ( -LRB- cord-035067-ic843wr9 170 4 p<0.001 p<0.001 CD cord-035067-ic843wr9 170 5 ) ) -RRB- cord-035067-ic843wr9 170 6 , , , cord-035067-ic843wr9 170 7 comorbidities comorbiditie NNS cord-035067-ic843wr9 170 8 ( ( -LRB- cord-035067-ic843wr9 170 9 p=0.002 p=0.002 NNP cord-035067-ic843wr9 170 10 ) ) -RRB- cord-035067-ic843wr9 170 11 , , , cord-035067-ic843wr9 170 12 and and CC cord-035067-ic843wr9 170 13 laboratory laboratory NN cord-035067-ic843wr9 170 14 abnormalities abnormality NNS cord-035067-ic843wr9 170 15 are be VBP cord-035067-ic843wr9 170 16 associated associate VBN cord-035067-ic843wr9 170 17 with with IN cord-035067-ic843wr9 170 18 severity severity NN cord-035067-ic843wr9 170 19 of of IN cord-035067-ic843wr9 170 20 the the DT cord-035067-ic843wr9 170 21 disease disease NN cord-035067-ic843wr9 170 22 . . . cord-035067-ic843wr9 171 1 These these DT cord-035067-ic843wr9 171 2 laboratory laboratory NN cord-035067-ic843wr9 171 3 values value NNS cord-035067-ic843wr9 171 4 are be VBP cord-035067-ic843wr9 171 5 high high JJ cord-035067-ic843wr9 171 6 D d NN cord-035067-ic843wr9 171 7 - - HYPH cord-035067-ic843wr9 171 8 dimer dimer NN cord-035067-ic843wr9 171 9 ( ( -LRB- cord-035067-ic843wr9 171 10 p<0.001 p<0.001 JJ cord-035067-ic843wr9 171 11 ) ) -RRB- cord-035067-ic843wr9 171 12 , , , cord-035067-ic843wr9 171 13 C c NN cord-035067-ic843wr9 171 14 - - HYPH cord-035067-ic843wr9 171 15 reactive reactive JJ cord-035067-ic843wr9 171 16 protein protein NN cord-035067-ic843wr9 171 17 ( ( -LRB- cord-035067-ic843wr9 171 18 p<0.001 p<0.001 NNP cord-035067-ic843wr9 171 19 ) ) -RRB- cord-035067-ic843wr9 171 20 , , , cord-035067-ic843wr9 171 21 procalcitonin procalcitonin NNP cord-035067-ic843wr9 171 22 ( ( -LRB- cord-035067-ic843wr9 171 23 p<0.001 p<0.001 JJ cord-035067-ic843wr9 171 24 ) ) -RRB- cord-035067-ic843wr9 171 25 , , , cord-035067-ic843wr9 171 26 and and CC cord-035067-ic843wr9 171 27 leukopenia leukopenia NN cord-035067-ic843wr9 171 28 ( ( -LRB- cord-035067-ic843wr9 171 29 p<0.014 p<0.014 CD cord-035067-ic843wr9 171 30 ) ) -RRB- cord-035067-ic843wr9 171 31 . . . cord-035067-ic843wr9 172 1 In in IN cord-035067-ic843wr9 172 2 this this DT cord-035067-ic843wr9 172 3 study study NN cord-035067-ic843wr9 172 4 , , , cord-035067-ic843wr9 172 5 patients patient NNS cord-035067-ic843wr9 172 6 with with IN cord-035067-ic843wr9 172 7 COPD COPD NNP cord-035067-ic843wr9 172 8 and and CC cord-035067-ic843wr9 172 9 smokers smoker NNS cord-035067-ic843wr9 172 10 had have VBD cord-035067-ic843wr9 172 11 a a DT cord-035067-ic843wr9 172 12 lower low JJR cord-035067-ic843wr9 172 13 risk risk NN cord-035067-ic843wr9 172 14 of of IN cord-035067-ic843wr9 172 15 being be VBG cord-035067-ic843wr9 172 16 infected infect VBN cord-035067-ic843wr9 172 17 by by IN cord-035067-ic843wr9 172 18 SARS SARS NNP cord-035067-ic843wr9 172 19 - - HYPH cord-035067-ic843wr9 172 20 CoV-2 CoV-2 NNP cord-035067-ic843wr9 172 21 , , , cord-035067-ic843wr9 172 22 but but CC cord-035067-ic843wr9 172 23 the the DT cord-035067-ic843wr9 172 24 progression progression NN cord-035067-ic843wr9 172 25 of of IN cord-035067-ic843wr9 172 26 the the DT cord-035067-ic843wr9 172 27 condition condition NN cord-035067-ic843wr9 172 28 in in IN cord-035067-ic843wr9 172 29 these these DT cord-035067-ic843wr9 172 30 patients patient NNS cord-035067-ic843wr9 172 31 was be VBD cord-035067-ic843wr9 172 32 more more RBR cord-035067-ic843wr9 172 33 severe severe JJ cord-035067-ic843wr9 172 34 . . . cord-035067-ic843wr9 173 1 However however RB cord-035067-ic843wr9 173 2 , , , cord-035067-ic843wr9 173 3 the the DT cord-035067-ic843wr9 173 4 relation relation NN cord-035067-ic843wr9 173 5 of of IN cord-035067-ic843wr9 173 6 smokers smoker NNS cord-035067-ic843wr9 173 7 with with IN cord-035067-ic843wr9 173 8 COVID-19 COVID-19 NNP cord-035067-ic843wr9 173 9 is be VBZ cord-035067-ic843wr9 173 10 still still RB cord-035067-ic843wr9 173 11 uncertain uncertain JJ cord-035067-ic843wr9 173 12 . . . cord-035067-ic843wr9 174 1 Smokers smoker NNS cord-035067-ic843wr9 174 2 and and CC cord-035067-ic843wr9 174 3 COPD COPD NNP cord-035067-ic843wr9 174 4 patients patient NNS cord-035067-ic843wr9 174 5 are be VBP cord-035067-ic843wr9 174 6 more more RBR cord-035067-ic843wr9 174 7 susceptible susceptible JJ cord-035067-ic843wr9 174 8 to to IN cord-035067-ic843wr9 174 9 MERS MERS NNP cord-035067-ic843wr9 174 10 - - HYPH cord-035067-ic843wr9 174 11 CoV cov NN cord-035067-ic843wr9 174 12 infections infection NNS cord-035067-ic843wr9 174 13 , , , cord-035067-ic843wr9 174 14 because because IN cord-035067-ic843wr9 174 15 tobacco tobacco NN cord-035067-ic843wr9 174 16 and and CC cord-035067-ic843wr9 174 17 COPD COPD NNP cord-035067-ic843wr9 174 18 increase increase VBP cord-035067-ic843wr9 174 19 the the DT cord-035067-ic843wr9 174 20 expression expression NN cord-035067-ic843wr9 174 21 of of IN cord-035067-ic843wr9 174 22 the the DT cord-035067-ic843wr9 174 23 DPP4 DPP4 NNP cord-035067-ic843wr9 174 24 carrier carrier NN cord-035067-ic843wr9 174 25 , , , cord-035067-ic843wr9 174 26 which which WDT cord-035067-ic843wr9 174 27 is be VBZ cord-035067-ic843wr9 174 28 the the DT cord-035067-ic843wr9 174 29 receptor receptor NN cord-035067-ic843wr9 174 30 for for IN cord-035067-ic843wr9 174 31 this this DT cord-035067-ic843wr9 174 32 virus virus NN cord-035067-ic843wr9 174 33 . . . cord-035067-ic843wr9 175 1 ( ( -LRB- cord-035067-ic843wr9 175 2 25 25 CD cord-035067-ic843wr9 175 3 ) ) -RRB- cord-035067-ic843wr9 176 1 Zhou Zhou NNP cord-035067-ic843wr9 176 2 et et NNP cord-035067-ic843wr9 176 3 al al NNP cord-035067-ic843wr9 176 4 . . . cord-035067-ic843wr9 177 1 , , , cord-035067-ic843wr9 177 2 evaluated evaluate VBD cord-035067-ic843wr9 177 3 254 254 CD cord-035067-ic843wr9 177 4 patients patient NNS cord-035067-ic843wr9 177 5 of of IN cord-035067-ic843wr9 177 6 a a DT cord-035067-ic843wr9 177 7 Wuhan Wuhan NNP cord-035067-ic843wr9 177 8 center center NN cord-035067-ic843wr9 177 9 with with IN cord-035067-ic843wr9 177 10 confirmation confirmation NN cord-035067-ic843wr9 177 11 of of IN cord-035067-ic843wr9 177 12 COVID-19 COVID-19 NNP cord-035067-ic843wr9 177 13 . . . cord-035067-ic843wr9 178 1 They -PRON- PRP cord-035067-ic843wr9 178 2 compared compare VBD cord-035067-ic843wr9 178 3 the the DT cord-035067-ic843wr9 178 4 infected infected JJ cord-035067-ic843wr9 178 5 medical medical JJ cord-035067-ic843wr9 178 6 team team NN cord-035067-ic843wr9 178 7 separately separately RB cord-035067-ic843wr9 178 8 from from IN cord-035067-ic843wr9 178 9 the the DT cord-035067-ic843wr9 178 10 non non JJ cord-035067-ic843wr9 178 11 - - JJ cord-035067-ic843wr9 178 12 medical medical JJ cord-035067-ic843wr9 178 13 patients patient NNS cord-035067-ic843wr9 178 14 . . . cord-035067-ic843wr9 179 1 In in IN cord-035067-ic843wr9 179 2 the the DT cord-035067-ic843wr9 179 3 sample sample NN cord-035067-ic843wr9 179 4 , , , cord-035067-ic843wr9 179 5 139 139 CD cord-035067-ic843wr9 179 6 were be VBD cord-035067-ic843wr9 179 7 women woman NNS cord-035067-ic843wr9 179 8 , , , cord-035067-ic843wr9 179 9 mean mean JJ cord-035067-ic843wr9 179 10 age age NN cord-035067-ic843wr9 179 11 was be VBD cord-035067-ic843wr9 179 12 50.6 50.6 CD cord-035067-ic843wr9 179 13 years year NNS cord-035067-ic843wr9 179 14 , , , cord-035067-ic843wr9 179 15 and and CC cord-035067-ic843wr9 179 16 161 161 CD cord-035067-ic843wr9 179 17 did do VBD cord-035067-ic843wr9 179 18 not not RB cord-035067-ic843wr9 179 19 belong belong VB cord-035067-ic843wr9 179 20 to to IN cord-035067-ic843wr9 179 21 the the DT cord-035067-ic843wr9 179 22 medical medical JJ cord-035067-ic843wr9 179 23 team team NN cord-035067-ic843wr9 179 24 . . . cord-035067-ic843wr9 180 1 The the DT cord-035067-ic843wr9 180 2 most most RBS cord-035067-ic843wr9 180 3 frequently frequently RB cord-035067-ic843wr9 180 4 reported report VBD cord-035067-ic843wr9 180 5 symptoms symptom NNS cord-035067-ic843wr9 180 6 in in IN cord-035067-ic843wr9 180 7 all all DT cord-035067-ic843wr9 180 8 patients patient NNS cord-035067-ic843wr9 180 9 were be VBD cord-035067-ic843wr9 180 10 fever fever NN cord-035067-ic843wr9 180 11 ( ( -LRB- cord-035067-ic843wr9 180 12 211 211 CD cord-035067-ic843wr9 180 13 ; ; : cord-035067-ic843wr9 180 14 83 83 CD cord-035067-ic843wr9 180 15 % % NN cord-035067-ic843wr9 180 16 ) ) -RRB- cord-035067-ic843wr9 180 17 , , , cord-035067-ic843wr9 180 18 cough cough NN cord-035067-ic843wr9 180 19 ( ( -LRB- cord-035067-ic843wr9 180 20 98 98 CD cord-035067-ic843wr9 180 21 ; ; : cord-035067-ic843wr9 180 22 38.6 38.6 CD cord-035067-ic843wr9 180 23 % % NN cord-035067-ic843wr9 180 24 ) ) -RRB- cord-035067-ic843wr9 180 25 , , , cord-035067-ic843wr9 180 26 and and CC cord-035067-ic843wr9 180 27 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 180 28 symptoms symptom NNS cord-035067-ic843wr9 180 29 ( ( -LRB- cord-035067-ic843wr9 180 30 66 66 CD cord-035067-ic843wr9 180 31 ; ; : cord-035067-ic843wr9 180 32 26 26 CD cord-035067-ic843wr9 180 33 % % NN cord-035067-ic843wr9 180 34 ) ) -RRB- cord-035067-ic843wr9 180 35 . . . cord-035067-ic843wr9 181 1 In in IN cord-035067-ic843wr9 181 2 non non JJ cord-035067-ic843wr9 181 3 - - JJ cord-035067-ic843wr9 181 4 medical medical JJ cord-035067-ic843wr9 181 5 patients patient NNS cord-035067-ic843wr9 181 6 , , , cord-035067-ic843wr9 181 7 the the DT cord-035067-ic843wr9 181 8 proportion proportion NN cord-035067-ic843wr9 181 9 of of IN cord-035067-ic843wr9 181 10 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 181 11 symptoms symptom NNS cord-035067-ic843wr9 181 12 in in IN cord-035067-ic843wr9 181 13 women woman NNS cord-035067-ic843wr9 181 14 was be VBD cord-035067-ic843wr9 181 15 significantly significantly RB cord-035067-ic843wr9 181 16 higher high JJR cord-035067-ic843wr9 181 17 than than IN cord-035067-ic843wr9 181 18 in in IN cord-035067-ic843wr9 181 19 men man NNS cord-035067-ic843wr9 181 20 ( ( -LRB- cord-035067-ic843wr9 181 21 62.8 62.8 CD cord-035067-ic843wr9 181 22 % % NN cord-035067-ic843wr9 181 23 versus versus IN cord-035067-ic843wr9 181 24 37.2 37.2 CD cord-035067-ic843wr9 181 25 % % NN cord-035067-ic843wr9 181 26 ; ; : cord-035067-ic843wr9 181 27 p=0.033 p=0.033 NNP cord-035067-ic843wr9 181 28 ) ) -RRB- cord-035067-ic843wr9 181 29 . . . cord-035067-ic843wr9 182 1 In in IN cord-035067-ic843wr9 182 2 addition addition NN cord-035067-ic843wr9 182 3 , , , cord-035067-ic843wr9 182 4 clinical clinical JJ cord-035067-ic843wr9 182 5 manifestations manifestation NNS cord-035067-ic843wr9 182 6 , , , cord-035067-ic843wr9 182 7 such such JJ cord-035067-ic843wr9 182 8 as as IN cord-035067-ic843wr9 182 9 sore sore JJ cord-035067-ic843wr9 182 10 throat throat NN cord-035067-ic843wr9 182 11 ( ( -LRB- cord-035067-ic843wr9 182 12 14 14 CD cord-035067-ic843wr9 182 13 % % NN cord-035067-ic843wr9 182 14 versus versus IN cord-035067-ic843wr9 182 15 3 3 CD cord-035067-ic843wr9 182 16 % % NN cord-035067-ic843wr9 182 17 ; ; : cord-035067-ic843wr9 182 18 p=0.023 p=0.023 NNP cord-035067-ic843wr9 182 19 ) ) -RRB- cord-035067-ic843wr9 182 20 , , , cord-035067-ic843wr9 182 21 dizziness dizziness NN cord-035067-ic843wr9 182 22 ( ( -LRB- cord-035067-ic843wr9 182 23 12 12 CD cord-035067-ic843wr9 182 24 % % NN cord-035067-ic843wr9 182 25 versus versus IN cord-035067-ic843wr9 182 26 3 3 CD cord-035067-ic843wr9 182 27 % % NN cord-035067-ic843wr9 182 28 ; ; : cord-035067-ic843wr9 182 29 p=0.032 p=0.032 NNP cord-035067-ic843wr9 182 30 ) ) -RRB- cord-035067-ic843wr9 182 31 , , , cord-035067-ic843wr9 182 32 fatigue fatigue NN cord-035067-ic843wr9 182 33 ( ( -LRB- cord-035067-ic843wr9 182 34 67 67 CD cord-035067-ic843wr9 182 35 % % NN cord-035067-ic843wr9 182 36 versus versus IN cord-035067-ic843wr9 182 37 44 44 CD cord-035067-ic843wr9 182 38 % % NN cord-035067-ic843wr9 182 39 ; ; : cord-035067-ic843wr9 182 40 p=0.012 p=0.012 NNP cord-035067-ic843wr9 182 41 ) ) -RRB- cord-035067-ic843wr9 182 42 , , , cord-035067-ic843wr9 182 43 low low JJ cord-035067-ic843wr9 182 44 hemoglobin hemoglobin NN cord-035067-ic843wr9 182 45 ( ( -LRB- cord-035067-ic843wr9 182 46 116.7 116.7 CD cord-035067-ic843wr9 182 47 versus versus IN cord-035067-ic843wr9 182 48 133 133 CD cord-035067-ic843wr9 182 49 ; ; : cord-035067-ic843wr9 182 50 p=0.028 p=0.028 ADD cord-035067-ic843wr9 182 51 ) ) -RRB- cord-035067-ic843wr9 182 52 , , , cord-035067-ic843wr9 182 53 high high JJ cord-035067-ic843wr9 182 54 C c NN cord-035067-ic843wr9 182 55 - - HYPH cord-035067-ic843wr9 182 56 reactive reactive JJ cord-035067-ic843wr9 182 57 protein protein NN cord-035067-ic843wr9 182 58 ( ( -LRB- cord-035067-ic843wr9 182 59 7.3 7.3 CD cord-035067-ic843wr9 182 60 versus versus IN cord-035067-ic843wr9 182 61 3.8 3.8 CD cord-035067-ic843wr9 182 62 ; ; : cord-035067-ic843wr9 182 63 p=0.021 p=0.021 NNP cord-035067-ic843wr9 182 64 ) ) -RRB- cord-035067-ic843wr9 182 65 , , , cord-035067-ic843wr9 182 66 and and CC cord-035067-ic843wr9 182 67 high high JJ cord-035067-ic843wr9 182 68 ALT alt NN cord-035067-ic843wr9 182 69 ( ( -LRB- cord-035067-ic843wr9 182 70 64.1 64.1 CD cord-035067-ic843wr9 182 71 versus versus IN cord-035067-ic843wr9 182 72 46.6 46.6 CD cord-035067-ic843wr9 182 73 ; ; : cord-035067-ic843wr9 182 74 p=0.049 p=0.049 NNP cord-035067-ic843wr9 182 75 ) ) -RRB- cord-035067-ic843wr9 182 76 , , , cord-035067-ic843wr9 182 77 were be VBD cord-035067-ic843wr9 182 78 also also RB cord-035067-ic843wr9 182 79 significantly significantly RB cord-035067-ic843wr9 182 80 more more RBR cord-035067-ic843wr9 182 81 frequent frequent JJ cord-035067-ic843wr9 182 82 in in IN cord-035067-ic843wr9 182 83 non non JJ cord-035067-ic843wr9 182 84 - - JJ cord-035067-ic843wr9 182 85 medical medical JJ cord-035067-ic843wr9 182 86 patients patient NNS cord-035067-ic843wr9 182 87 with with IN cord-035067-ic843wr9 182 88 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 182 89 symptoms symptom NNS cord-035067-ic843wr9 182 90 . . . cord-035067-ic843wr9 183 1 Nonetheless nonetheless RB cord-035067-ic843wr9 183 2 , , , cord-035067-ic843wr9 183 3 there there EX cord-035067-ic843wr9 183 4 was be VBD cord-035067-ic843wr9 183 5 no no DT cord-035067-ic843wr9 183 6 significant significant JJ cord-035067-ic843wr9 183 7 correlation correlation NN cord-035067-ic843wr9 183 8 between between IN cord-035067-ic843wr9 183 9 symptoms symptom NNS cord-035067-ic843wr9 183 10 and and CC cord-035067-ic843wr9 183 11 clinical clinical JJ cord-035067-ic843wr9 183 12 characteristics characteristic NNS cord-035067-ic843wr9 183 13 of of IN cord-035067-ic843wr9 183 14 patients patient NNS cord-035067-ic843wr9 183 15 with with IN cord-035067-ic843wr9 183 16 and and CC cord-035067-ic843wr9 183 17 without without IN cord-035067-ic843wr9 183 18 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 183 19 symptoms symptom NNS cord-035067-ic843wr9 183 20 . . . cord-035067-ic843wr9 184 1 An an DT cord-035067-ic843wr9 184 2 explanation explanation NN cord-035067-ic843wr9 184 3 of of IN cord-035067-ic843wr9 184 4 why why WRB cord-035067-ic843wr9 184 5 the the DT cord-035067-ic843wr9 184 6 medical medical JJ cord-035067-ic843wr9 184 7 team team NN cord-035067-ic843wr9 184 8 was be VBD cord-035067-ic843wr9 184 9 less less RBR cord-035067-ic843wr9 184 10 susceptible susceptible JJ cord-035067-ic843wr9 184 11 to to IN cord-035067-ic843wr9 184 12 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 184 13 symptoms symptom NNS cord-035067-ic843wr9 184 14 is be VBZ cord-035067-ic843wr9 184 15 that that IN cord-035067-ic843wr9 184 16 most most JJS cord-035067-ic843wr9 184 17 of of IN cord-035067-ic843wr9 184 18 this this DT cord-035067-ic843wr9 184 19 group group NN cord-035067-ic843wr9 184 20 was be VBD cord-035067-ic843wr9 184 21 made make VBN cord-035067-ic843wr9 184 22 up up RP cord-035067-ic843wr9 184 23 of of IN cord-035067-ic843wr9 184 24 young young JJ cord-035067-ic843wr9 184 25 nurses nurse NNS cord-035067-ic843wr9 184 26 with with IN cord-035067-ic843wr9 184 27 no no DT cord-035067-ic843wr9 184 28 comorbidities comorbiditie NNS cord-035067-ic843wr9 184 29 . . . cord-035067-ic843wr9 185 1 This this DT cord-035067-ic843wr9 185 2 study study NN cord-035067-ic843wr9 185 3 has have VBZ cord-035067-ic843wr9 185 4 limitations limitation NNS cord-035067-ic843wr9 185 5 . . . cord-035067-ic843wr9 186 1 Most Most JJS cord-035067-ic843wr9 186 2 of of IN cord-035067-ic843wr9 186 3 the the DT cord-035067-ic843wr9 186 4 cases case NNS cord-035067-ic843wr9 186 5 included include VBN cord-035067-ic843wr9 186 6 were be VBD cord-035067-ic843wr9 186 7 clinically clinically RB cord-035067-ic843wr9 186 8 confirmed confirm VBN cord-035067-ic843wr9 186 9 , , , cord-035067-ic843wr9 186 10 therefore therefore RB cord-035067-ic843wr9 186 11 it -PRON- PRP cord-035067-ic843wr9 186 12 has have VBZ cord-035067-ic843wr9 186 13 patients patient NNS cord-035067-ic843wr9 186 14 without without IN cord-035067-ic843wr9 186 15 the the DT cord-035067-ic843wr9 186 16 PCR PCR NNP cord-035067-ic843wr9 186 17 test test NN cord-035067-ic843wr9 186 18 for for IN cord-035067-ic843wr9 186 19 SARS SARS NNP cord-035067-ic843wr9 186 20 - - HYPH cord-035067-ic843wr9 186 21 CoV-2 CoV-2 NNP cord-035067-ic843wr9 186 22 . . . cord-035067-ic843wr9 187 1 Additionally additionally RB cord-035067-ic843wr9 187 2 , , , cord-035067-ic843wr9 187 3 many many JJ cord-035067-ic843wr9 187 4 patients patient NNS cord-035067-ic843wr9 187 5 did do VBD cord-035067-ic843wr9 187 6 not not RB cord-035067-ic843wr9 187 7 have have VB cord-035067-ic843wr9 187 8 follow follow VB cord-035067-ic843wr9 187 9 - - HYPH cord-035067-ic843wr9 187 10 up up NN cord-035067-ic843wr9 187 11 , , , cord-035067-ic843wr9 187 12 since since IN cord-035067-ic843wr9 187 13 they -PRON- PRP cord-035067-ic843wr9 187 14 were be VBD cord-035067-ic843wr9 187 15 still still RB cord-035067-ic843wr9 187 16 hospitalized hospitalize VBN cord-035067-ic843wr9 187 17 at at IN cord-035067-ic843wr9 187 18 the the DT cord-035067-ic843wr9 187 19 time time NN cord-035067-ic843wr9 187 20 of of IN cord-035067-ic843wr9 187 21 submission submission NN cord-035067-ic843wr9 187 22 of of IN cord-035067-ic843wr9 187 23 this this DT cord-035067-ic843wr9 187 24 article article NN cord-035067-ic843wr9 187 25 . . . cord-035067-ic843wr9 188 1 ( ( -LRB- cord-035067-ic843wr9 188 2 26 26 CD cord-035067-ic843wr9 188 3 ) ) -RRB- cord-035067-ic843wr9 189 1 Cipriano Cipriano NNP cord-035067-ic843wr9 189 2 et et NNP cord-035067-ic843wr9 189 3 al al NNP cord-035067-ic843wr9 189 4 . . NNP cord-035067-ic843wr9 189 5 , , , cord-035067-ic843wr9 189 6 conducted conduct VBD cord-035067-ic843wr9 189 7 a a DT cord-035067-ic843wr9 189 8 systematic systematic JJ cord-035067-ic843wr9 189 9 review review NN cord-035067-ic843wr9 189 10 with with IN cord-035067-ic843wr9 189 11 six six CD cord-035067-ic843wr9 189 12 studies study NNS cord-035067-ic843wr9 189 13 of of IN cord-035067-ic843wr9 189 14 patients patient NNS cord-035067-ic843wr9 189 15 from from IN cord-035067-ic843wr9 189 16 China China NNP cord-035067-ic843wr9 189 17 , , , cord-035067-ic843wr9 189 18 which which WDT cord-035067-ic843wr9 189 19 points point VBZ cord-035067-ic843wr9 189 20 to to IN cord-035067-ic843wr9 189 21 the the DT cord-035067-ic843wr9 189 22 possibility possibility NN cord-035067-ic843wr9 189 23 of of IN cord-035067-ic843wr9 189 24 SARS SARS NNP cord-035067-ic843wr9 189 25 - - HYPH cord-035067-ic843wr9 189 26 CoV-2 CoV-2 NNP cord-035067-ic843wr9 189 27 infection infection NN cord-035067-ic843wr9 189 28 in in IN cord-035067-ic843wr9 189 29 the the DT cord-035067-ic843wr9 189 30 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 189 31 tract tract NN cord-035067-ic843wr9 189 32 and and CC cord-035067-ic843wr9 189 33 fecal fecal JJ cord-035067-ic843wr9 189 34 - - HYPH cord-035067-ic843wr9 189 35 oral oral JJ cord-035067-ic843wr9 189 36 transmission transmission NN cord-035067-ic843wr9 189 37 . . . cord-035067-ic843wr9 190 1 In in IN cord-035067-ic843wr9 190 2 the the DT cord-035067-ic843wr9 190 3 study study NN cord-035067-ic843wr9 190 4 , , , cord-035067-ic843wr9 190 5 53.42 53.42 CD cord-035067-ic843wr9 190 6 % % NN cord-035067-ic843wr9 190 7 of of IN cord-035067-ic843wr9 190 8 stool stool NN cord-035067-ic843wr9 190 9 samples sample NNS cord-035067-ic843wr9 190 10 tested test VBD cord-035067-ic843wr9 190 11 positive positive JJ cord-035067-ic843wr9 190 12 for for IN cord-035067-ic843wr9 190 13 the the DT cord-035067-ic843wr9 190 14 presence presence NN cord-035067-ic843wr9 190 15 of of IN cord-035067-ic843wr9 190 16 SARS SARS NNP cord-035067-ic843wr9 190 17 - - HYPH cord-035067-ic843wr9 190 18 CoV-2 CoV-2 NNP cord-035067-ic843wr9 190 19 RNA RNA NNP cord-035067-ic843wr9 190 20 in in IN cord-035067-ic843wr9 190 21 73 73 CD cord-035067-ic843wr9 190 22 hospitalized hospitalize VBN cord-035067-ic843wr9 190 23 patients patient NNS cord-035067-ic843wr9 190 24 . . . cord-035067-ic843wr9 191 1 These these DT cord-035067-ic843wr9 191 2 samples sample NNS cord-035067-ic843wr9 191 3 remained remain VBD cord-035067-ic843wr9 191 4 positive positive JJ cord-035067-ic843wr9 191 5 between between IN cord-035067-ic843wr9 191 6 one one CD cord-035067-ic843wr9 191 7 and and CC cord-035067-ic843wr9 191 8 12 12 CD cord-035067-ic843wr9 191 9 days day NNS cord-035067-ic843wr9 191 10 , , , cord-035067-ic843wr9 191 11 and and CC cord-035067-ic843wr9 191 12 23.29 23.29 CD cord-035067-ic843wr9 191 13 % % NN cord-035067-ic843wr9 191 14 of of IN cord-035067-ic843wr9 191 15 patients patient NNS cord-035067-ic843wr9 191 16 had have VBD cord-035067-ic843wr9 191 17 feces fece NNS cord-035067-ic843wr9 191 18 positive positive JJ cord-035067-ic843wr9 191 19 for for IN cord-035067-ic843wr9 191 20 the the DT cord-035067-ic843wr9 191 21 virus virus NN cord-035067-ic843wr9 191 22 RNA RNA NNP cord-035067-ic843wr9 191 23 after after IN cord-035067-ic843wr9 191 24 the the DT cord-035067-ic843wr9 191 25 respiratory respiratory JJ cord-035067-ic843wr9 191 26 samples sample NNS cord-035067-ic843wr9 191 27 tested test VBN cord-035067-ic843wr9 191 28 negative negative JJ cord-035067-ic843wr9 191 29 . . . cord-035067-ic843wr9 192 1 The the DT cord-035067-ic843wr9 192 2 authors author NNS cord-035067-ic843wr9 192 3 conclude conclude VBP cord-035067-ic843wr9 192 4 that that IN cord-035067-ic843wr9 192 5 the the DT cord-035067-ic843wr9 192 6 anal anal JJ cord-035067-ic843wr9 192 7 swab swab NN cord-035067-ic843wr9 192 8 can can MD cord-035067-ic843wr9 192 9 be be VB cord-035067-ic843wr9 192 10 as as RB cord-035067-ic843wr9 192 11 important important JJ cord-035067-ic843wr9 192 12 as as IN cord-035067-ic843wr9 192 13 the the DT cord-035067-ic843wr9 192 14 nasopharyngeal nasopharyngeal JJ cord-035067-ic843wr9 192 15 swab swab NN cord-035067-ic843wr9 192 16 , , , cord-035067-ic843wr9 192 17 even even RB cord-035067-ic843wr9 192 18 in in IN cord-035067-ic843wr9 192 19 asymptomatic asymptomatic JJ cord-035067-ic843wr9 192 20 patients patient NNS cord-035067-ic843wr9 192 21 . . . cord-035067-ic843wr9 193 1 Before before IN cord-035067-ic843wr9 193 2 hospital hospital NN cord-035067-ic843wr9 193 3 discharge discharge NN cord-035067-ic843wr9 193 4 , , , cord-035067-ic843wr9 193 5 physicians physician NNS cord-035067-ic843wr9 193 6 should should MD cord-035067-ic843wr9 193 7 consider consider VB cord-035067-ic843wr9 193 8 that that IN cord-035067-ic843wr9 193 9 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 193 10 infection infection NN cord-035067-ic843wr9 193 11 and and CC cord-035067-ic843wr9 193 12 potential potential JJ cord-035067-ic843wr9 193 13 fecal fecal JJ cord-035067-ic843wr9 193 14 - - HYPH cord-035067-ic843wr9 193 15 oral oral JJ cord-035067-ic843wr9 193 16 transmission transmission NN cord-035067-ic843wr9 193 17 may may MD cord-035067-ic843wr9 193 18 remain remain VB cord-035067-ic843wr9 193 19 until until IN cord-035067-ic843wr9 193 20 after after IN cord-035067-ic843wr9 193 21 the the DT cord-035067-ic843wr9 193 22 viral viral JJ cord-035067-ic843wr9 193 23 disappearance disappearance NN cord-035067-ic843wr9 193 24 of of IN cord-035067-ic843wr9 193 25 the the DT cord-035067-ic843wr9 193 26 respiratory respiratory JJ cord-035067-ic843wr9 193 27 tract tract NN cord-035067-ic843wr9 193 28 . . . cord-035067-ic843wr9 194 1 ( ( -LRB- cord-035067-ic843wr9 194 2 30 30 CD cord-035067-ic843wr9 194 3 ) ) -RRB- cord-035067-ic843wr9 195 1 Cheung Cheung NNP cord-035067-ic843wr9 195 2 et et NNP cord-035067-ic843wr9 195 3 al al NNP cord-035067-ic843wr9 195 4 . . . cord-035067-ic843wr9 196 1 , , , cord-035067-ic843wr9 196 2 did do VBD cord-035067-ic843wr9 196 3 an an DT cord-035067-ic843wr9 196 4 interesting interesting JJ cord-035067-ic843wr9 196 5 study study NN cord-035067-ic843wr9 196 6 on on IN cord-035067-ic843wr9 196 7 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 196 8 symptoms symptom NNS cord-035067-ic843wr9 196 9 of of IN cord-035067-ic843wr9 196 10 COVID-19 COVID-19 NNP cord-035067-ic843wr9 196 11 and and CC cord-035067-ic843wr9 196 12 the the DT cord-035067-ic843wr9 196 13 presence presence NN cord-035067-ic843wr9 196 14 of of IN cord-035067-ic843wr9 196 15 viral viral JJ cord-035067-ic843wr9 196 16 RNA RNA NNP cord-035067-ic843wr9 196 17 in in IN cord-035067-ic843wr9 196 18 feces fece NNS cord-035067-ic843wr9 196 19 . . . cord-035067-ic843wr9 197 1 They -PRON- PRP cord-035067-ic843wr9 197 2 compared compare VBD cord-035067-ic843wr9 197 3 a a DT cord-035067-ic843wr9 197 4 metaanalysis metaanalysis NN cord-035067-ic843wr9 197 5 with with IN cord-035067-ic843wr9 197 6 a a DT cord-035067-ic843wr9 197 7 Hong Hong NNP cord-035067-ic843wr9 197 8 Kong Kong NNP cord-035067-ic843wr9 197 9 cohort cohort NN cord-035067-ic843wr9 197 10 . . . cord-035067-ic843wr9 198 1 In in IN cord-035067-ic843wr9 198 2 a a DT cord-035067-ic843wr9 198 3 cohort cohort NN cord-035067-ic843wr9 198 4 of of IN cord-035067-ic843wr9 198 5 59 59 CD cord-035067-ic843wr9 198 6 patients patient NNS cord-035067-ic843wr9 198 7 with with IN cord-035067-ic843wr9 198 8 the the DT cord-035067-ic843wr9 198 9 disease disease NN cord-035067-ic843wr9 198 10 , , , cord-035067-ic843wr9 198 11 15 15 CD cord-035067-ic843wr9 198 12 ( ( -LRB- cord-035067-ic843wr9 198 13 25.4 25.4 CD cord-035067-ic843wr9 198 14 % % NN cord-035067-ic843wr9 198 15 ) ) -RRB- cord-035067-ic843wr9 198 16 presented present VBN cord-035067-ic843wr9 198 17 with with IN cord-035067-ic843wr9 198 18 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 198 19 symptoms symptom NNS cord-035067-ic843wr9 198 20 , , , cord-035067-ic843wr9 198 21 and and CC cord-035067-ic843wr9 198 22 9 9 CD cord-035067-ic843wr9 198 23 ( ( -LRB- cord-035067-ic843wr9 198 24 15.3 15.3 CD cord-035067-ic843wr9 198 25 % % NN cord-035067-ic843wr9 198 26 ) ) -RRB- cord-035067-ic843wr9 198 27 had have VBD cord-035067-ic843wr9 198 28 their -PRON- PRP$ cord-035067-ic843wr9 198 29 feces fece NNS cord-035067-ic843wr9 198 30 tested test VBN cord-035067-ic843wr9 198 31 positive positive JJ cord-035067-ic843wr9 198 32 for for IN cord-035067-ic843wr9 198 33 viral viral JJ cord-035067-ic843wr9 198 34 RNA RNA NNP cord-035067-ic843wr9 198 35 ; ; : cord-035067-ic843wr9 198 36 38.5 38.5 CD cord-035067-ic843wr9 198 37 % % NN cord-035067-ic843wr9 198 38 and and CC cord-035067-ic843wr9 198 39 8.7 8.7 CD cord-035067-ic843wr9 198 40 % % NN cord-035067-ic843wr9 198 41 of of IN cord-035067-ic843wr9 198 42 those those DT cord-035067-ic843wr9 198 43 with with IN cord-035067-ic843wr9 198 44 and and CC cord-035067-ic843wr9 198 45 without without IN cord-035067-ic843wr9 198 46 diarrhea diarrhea NN cord-035067-ic843wr9 198 47 , , , cord-035067-ic843wr9 198 48 respectively respectively RB cord-035067-ic843wr9 198 49 ( ( -LRB- cord-035067-ic843wr9 198 50 p=0.019 p=0.019 NNP cord-035067-ic843wr9 198 51 ) ) -RRB- cord-035067-ic843wr9 198 52 , , , cord-035067-ic843wr9 198 53 had have VBD cord-035067-ic843wr9 198 54 stool stool NN cord-035067-ic843wr9 198 55 viral viral JJ cord-035067-ic843wr9 198 56 RNA RNA NNP cord-035067-ic843wr9 198 57 detected detect VBD cord-035067-ic843wr9 198 58 . . . cord-035067-ic843wr9 199 1 In in IN cord-035067-ic843wr9 199 2 the the DT cord-035067-ic843wr9 199 3 meta meta JJ cord-035067-ic843wr9 199 4 - - HYPH cord-035067-ic843wr9 199 5 analysis analysis NNP cord-035067-ic843wr9 199 6 , , , cord-035067-ic843wr9 199 7 which which WDT cord-035067-ic843wr9 199 8 included include VBD cord-035067-ic843wr9 199 9 60 60 CD cord-035067-ic843wr9 199 10 studies study NNS cord-035067-ic843wr9 199 11 and and CC cord-035067-ic843wr9 199 12 4,243 4,243 CD cord-035067-ic843wr9 199 13 patients patient NNS cord-035067-ic843wr9 199 14 , , , cord-035067-ic843wr9 199 15 the the DT cord-035067-ic843wr9 199 16 prevalence prevalence NN cord-035067-ic843wr9 199 17 of of IN cord-035067-ic843wr9 199 18 patients patient NNS cord-035067-ic843wr9 199 19 with with IN cord-035067-ic843wr9 199 20 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 199 21 symptoms symptom NNS cord-035067-ic843wr9 199 22 was be VBD cord-035067-ic843wr9 199 23 17.6 17.6 CD cord-035067-ic843wr9 199 24 % % NN cord-035067-ic843wr9 199 25 ; ; , cord-035067-ic843wr9 199 26 in in IN cord-035067-ic843wr9 199 27 that that DT cord-035067-ic843wr9 199 28 , , , cord-035067-ic843wr9 199 29 16 16 CD cord-035067-ic843wr9 199 30 .1 .1 CD cord-035067-ic843wr9 199 31 % % NN cord-035067-ic843wr9 199 32 in in IN cord-035067-ic843wr9 199 33 studies study NNS cord-035067-ic843wr9 199 34 from from IN cord-035067-ic843wr9 199 35 China China NNP cord-035067-ic843wr9 199 36 , , , cord-035067-ic843wr9 199 37 and and CC cord-035067-ic843wr9 199 38 33.4 33.4 CD cord-035067-ic843wr9 199 39 % % NN cord-035067-ic843wr9 199 40 from from IN cord-035067-ic843wr9 199 41 other other JJ cord-035067-ic843wr9 199 42 countries country NNS cord-035067-ic843wr9 199 43 ( ( -LRB- cord-035067-ic843wr9 199 44 South South NNP cord-035067-ic843wr9 199 45 Korea Korea NNP cord-035067-ic843wr9 199 46 , , , cord-035067-ic843wr9 199 47 Singapore Singapore NNP cord-035067-ic843wr9 199 48 , , , cord-035067-ic843wr9 199 49 Vietnam Vietnam NNP cord-035067-ic843wr9 199 50 , , , cord-035067-ic843wr9 199 51 United United NNP cord-035067-ic843wr9 199 52 States States NNP cord-035067-ic843wr9 199 53 , , , cord-035067-ic843wr9 199 54 and and CC cord-035067-ic843wr9 199 55 United United NNP cord-035067-ic843wr9 199 56 Kingdom Kingdom NNP cord-035067-ic843wr9 199 57 ) ) -RRB- cord-035067-ic843wr9 199 58 . . . cord-035067-ic843wr9 200 1 The the DT cord-035067-ic843wr9 200 2 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 200 3 symptoms symptom NNS cord-035067-ic843wr9 200 4 evaluated evaluate VBN cord-035067-ic843wr9 200 5 were be VBD cord-035067-ic843wr9 200 6 anorexia anorexia VBN cord-035067-ic843wr9 200 7 ( ( -LRB- cord-035067-ic843wr9 200 8 26.8 26.8 CD cord-035067-ic843wr9 200 9 % % NN cord-035067-ic843wr9 200 10 ) ) -RRB- cord-035067-ic843wr9 200 11 , , , cord-035067-ic843wr9 200 12 diarrhea diarrhea NN cord-035067-ic843wr9 200 13 ( ( -LRB- cord-035067-ic843wr9 200 14 12.5 12.5 CD cord-035067-ic843wr9 200 15 % % NN cord-035067-ic843wr9 200 16 ) ) -RRB- cord-035067-ic843wr9 200 17 , , , cord-035067-ic843wr9 200 18 nausea nausea NN cord-035067-ic843wr9 200 19 / / SYM cord-035067-ic843wr9 200 20 vomiting vomiting NN cord-035067-ic843wr9 200 21 ( ( -LRB- cord-035067-ic843wr9 200 22 10.2 10.2 CD cord-035067-ic843wr9 200 23 % % NN cord-035067-ic843wr9 200 24 ) ) -RRB- cord-035067-ic843wr9 200 25 , , , cord-035067-ic843wr9 200 26 and and CC cord-035067-ic843wr9 200 27 abdominal abdominal JJ cord-035067-ic843wr9 200 28 pain pain NN cord-035067-ic843wr9 200 29 ( ( -LRB- cord-035067-ic843wr9 200 30 9.2 9.2 CD cord-035067-ic843wr9 200 31 % % NN cord-035067-ic843wr9 200 32 ) ) -RRB- cord-035067-ic843wr9 200 33 . . . cord-035067-ic843wr9 201 1 The the DT cord-035067-ic843wr9 201 2 prevalence prevalence NN cord-035067-ic843wr9 201 3 of of IN cord-035067-ic843wr9 201 4 RNA RNA NNP cord-035067-ic843wr9 201 5 of of IN cord-035067-ic843wr9 201 6 the the DT cord-035067-ic843wr9 201 7 virus virus NN cord-035067-ic843wr9 201 8 in in IN cord-035067-ic843wr9 201 9 feces fece NNS cord-035067-ic843wr9 201 10 was be VBD cord-035067-ic843wr9 201 11 48.1 48.1 CD cord-035067-ic843wr9 201 12 % % NN cord-035067-ic843wr9 201 13 . . . cord-035067-ic843wr9 202 1 Of of IN cord-035067-ic843wr9 202 2 these these DT cord-035067-ic843wr9 202 3 samples sample NNS cord-035067-ic843wr9 202 4 , , , cord-035067-ic843wr9 202 5 70.3 70.3 CD cord-035067-ic843wr9 202 6 % % NN cord-035067-ic843wr9 202 7 einstein einstein NNP cord-035067-ic843wr9 202 8 ( ( -LRB- cord-035067-ic843wr9 202 9 São São NNP cord-035067-ic843wr9 202 10 Paulo Paulo NNP cord-035067-ic843wr9 202 11 ) ) -RRB- cord-035067-ic843wr9 202 12 . . . cord-035067-ic843wr9 203 1 2020;18:1 2020;18:1 CD cord-035067-ic843wr9 203 2 - - SYM cord-035067-ic843wr9 203 3 14 14 CD cord-035067-ic843wr9 203 4 tested test VBN cord-035067-ic843wr9 203 5 positive positive JJ cord-035067-ic843wr9 203 6 in in IN cord-035067-ic843wr9 203 7 the the DT cord-035067-ic843wr9 203 8 feces fece NNS cord-035067-ic843wr9 203 9 and and CC cord-035067-ic843wr9 203 10 could could MD cord-035067-ic843wr9 203 11 persist persist VB cord-035067-ic843wr9 203 12 for for IN cord-035067-ic843wr9 203 13 more more JJR cord-035067-ic843wr9 203 14 than than IN cord-035067-ic843wr9 203 15 33 33 CD cord-035067-ic843wr9 203 16 days day NNS cord-035067-ic843wr9 203 17 from from IN cord-035067-ic843wr9 203 18 the the DT cord-035067-ic843wr9 203 19 onset onset NN cord-035067-ic843wr9 203 20 of of IN cord-035067-ic843wr9 203 21 symptoms symptom NNS cord-035067-ic843wr9 203 22 , , , cord-035067-ic843wr9 203 23 even even RB cord-035067-ic843wr9 203 24 after after IN cord-035067-ic843wr9 203 25 the the DT cord-035067-ic843wr9 203 26 respiratory respiratory JJ cord-035067-ic843wr9 203 27 system system NN cord-035067-ic843wr9 203 28 had have VBD cord-035067-ic843wr9 203 29 resulted result VBN cord-035067-ic843wr9 203 30 negative negative JJ cord-035067-ic843wr9 203 31 for for IN cord-035067-ic843wr9 203 32 viral viral JJ cord-035067-ic843wr9 203 33 RNA RNA NNP cord-035067-ic843wr9 203 34 . . . cord-035067-ic843wr9 204 1 This this DT cord-035067-ic843wr9 204 2 meta meta JJ cord-035067-ic843wr9 204 3 - - HYPH cord-035067-ic843wr9 204 4 analysis analysis NN cord-035067-ic843wr9 204 5 also also RB cord-035067-ic843wr9 204 6 showed show VBD cord-035067-ic843wr9 204 7 the the DT cord-035067-ic843wr9 204 8 prevalence prevalence NN cord-035067-ic843wr9 204 9 of of IN cord-035067-ic843wr9 204 10 severe severe JJ cord-035067-ic843wr9 204 11 disease disease NN cord-035067-ic843wr9 204 12 was be VBD cord-035067-ic843wr9 204 13 more more RBR cord-035067-ic843wr9 204 14 common common JJ cord-035067-ic843wr9 204 15 in in IN cord-035067-ic843wr9 204 16 patients patient NNS cord-035067-ic843wr9 204 17 with with IN cord-035067-ic843wr9 204 18 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 204 19 symptoms symptom NNS cord-035067-ic843wr9 204 20 than than IN cord-035067-ic843wr9 204 21 in in IN cord-035067-ic843wr9 204 22 those those DT cord-035067-ic843wr9 204 23 without without IN cord-035067-ic843wr9 204 24 ( ( -LRB- cord-035067-ic843wr9 204 25 17.1 17.1 CD cord-035067-ic843wr9 204 26 % % NN cord-035067-ic843wr9 204 27 versus versus IN cord-035067-ic843wr9 204 28 11.8 11.8 CD cord-035067-ic843wr9 204 29 % % NN cord-035067-ic843wr9 204 30 ) ) -RRB- cord-035067-ic843wr9 204 31 . . . cord-035067-ic843wr9 205 1 The the DT cord-035067-ic843wr9 205 2 study study NN cord-035067-ic843wr9 205 3 limitations limitation NNS cord-035067-ic843wr9 205 4 are be VBP cord-035067-ic843wr9 205 5 underreporting underreporte VBG cord-035067-ic843wr9 205 6 of of IN cord-035067-ic843wr9 205 7 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 205 8 symptoms symptom NNS cord-035067-ic843wr9 205 9 and and CC cord-035067-ic843wr9 205 10 fewer few JJR cord-035067-ic843wr9 205 11 studies study NNS cord-035067-ic843wr9 205 12 outside outside IN cord-035067-ic843wr9 205 13 China China NNP cord-035067-ic843wr9 205 14 . . . cord-035067-ic843wr9 206 1 Thus thus RB cord-035067-ic843wr9 206 2 , , , cord-035067-ic843wr9 206 3 healthcare healthcare NN cord-035067-ic843wr9 206 4 professionals professional NNS cord-035067-ic843wr9 206 5 should should MD cord-035067-ic843wr9 206 6 pay pay VB cord-035067-ic843wr9 206 7 attention attention NN cord-035067-ic843wr9 206 8 to to IN cord-035067-ic843wr9 206 9 stool stool NN cord-035067-ic843wr9 206 10 collection collection NN cord-035067-ic843wr9 206 11 and and CC cord-035067-ic843wr9 206 12 procedures procedure NNS cord-035067-ic843wr9 206 13 , , , cord-035067-ic843wr9 206 14 such such JJ cord-035067-ic843wr9 206 15 as as IN cord-035067-ic843wr9 206 16 endoscopy endoscopy NN cord-035067-ic843wr9 206 17 in in IN cord-035067-ic843wr9 206 18 patients patient NNS cord-035067-ic843wr9 206 19 with with IN cord-035067-ic843wr9 206 20 COVID-19 COVID-19 NNP cord-035067-ic843wr9 206 21 . . . cord-035067-ic843wr9 207 1 ( ( -LRB- cord-035067-ic843wr9 207 2 27 27 CD cord-035067-ic843wr9 207 3 ) ) -RRB- cord-035067-ic843wr9 208 1 The the DT cord-035067-ic843wr9 208 2 systematic systematic JJ cord-035067-ic843wr9 208 3 review review NN cord-035067-ic843wr9 208 4 and and CC cord-035067-ic843wr9 208 5 meta meta NNP cord-035067-ic843wr9 208 6 - - HYPH cord-035067-ic843wr9 208 7 analysis analysis NN cord-035067-ic843wr9 208 8 with with IN cord-035067-ic843wr9 208 9 31 31 CD cord-035067-ic843wr9 208 10 articles article NNS cord-035067-ic843wr9 208 11 and and CC cord-035067-ic843wr9 208 12 46,959 46,959 CD cord-035067-ic843wr9 208 13 patients patient NNS cord-035067-ic843wr9 208 14 from from IN cord-035067-ic843wr9 208 15 China China NNP cord-035067-ic843wr9 208 16 , , , cord-035067-ic843wr9 208 17 by by IN cord-035067-ic843wr9 208 18 Cao Cao NNP cord-035067-ic843wr9 208 19 et et NNP cord-035067-ic843wr9 208 20 al al NNP cord-035067-ic843wr9 208 21 . . NNP cord-035067-ic843wr9 208 22 , , , cord-035067-ic843wr9 208 23 described describe VBD cord-035067-ic843wr9 208 24 the the DT cord-035067-ic843wr9 208 25 prevalence prevalence NN cord-035067-ic843wr9 208 26 of of IN cord-035067-ic843wr9 208 27 symptoms symptom NNS cord-035067-ic843wr9 208 28 such such JJ cord-035067-ic843wr9 208 29 as as IN cord-035067-ic843wr9 208 30 fever fever NN cord-035067-ic843wr9 208 31 ( ( -LRB- cord-035067-ic843wr9 208 32 87.3 87.3 CD cord-035067-ic843wr9 208 33 % % NN cord-035067-ic843wr9 208 34 ) ) -RRB- cord-035067-ic843wr9 208 35 , , , cord-035067-ic843wr9 208 36 dry dry JJ cord-035067-ic843wr9 208 37 cough cough NN cord-035067-ic843wr9 208 38 ( ( -LRB- cord-035067-ic843wr9 208 39 58.1 58.1 CD cord-035067-ic843wr9 208 40 % % NN cord-035067-ic843wr9 208 41 ) ) -RRB- cord-035067-ic843wr9 208 42 , , , cord-035067-ic843wr9 208 43 dyspnea dyspnea NN cord-035067-ic843wr9 208 44 ( ( -LRB- cord-035067-ic843wr9 208 45 38.2 38.2 CD cord-035067-ic843wr9 208 46 % % NN cord-035067-ic843wr9 208 47 ) ) -RRB- cord-035067-ic843wr9 208 48 , , , cord-035067-ic843wr9 208 49 myalgia myalgia NN cord-035067-ic843wr9 208 50 or or CC cord-035067-ic843wr9 208 51 fatigue fatigue NN cord-035067-ic843wr9 208 52 ( ( -LRB- cord-035067-ic843wr9 208 53 35.5 35.5 CD cord-035067-ic843wr9 208 54 % % NN cord-035067-ic843wr9 208 55 ) ) -RRB- cord-035067-ic843wr9 208 56 , , , cord-035067-ic843wr9 208 57 chest chest NN cord-035067-ic843wr9 208 58 pain pain NN cord-035067-ic843wr9 208 59 ( ( -LRB- cord-035067-ic843wr9 208 60 31.2 31.2 CD cord-035067-ic843wr9 208 61 % % NN cord-035067-ic843wr9 208 62 ) ) -RRB- cord-035067-ic843wr9 208 63 , , , cord-035067-ic843wr9 208 64 productive productive JJ cord-035067-ic843wr9 208 65 cough cough NN cord-035067-ic843wr9 208 66 ( ( -LRB- cord-035067-ic843wr9 208 67 29.4 29.4 CD cord-035067-ic843wr9 208 68 % % NN cord-035067-ic843wr9 208 69 ) ) -RRB- cord-035067-ic843wr9 208 70 , , , cord-035067-ic843wr9 208 71 sore sore JJ cord-035067-ic843wr9 208 72 throat throat NN cord-035067-ic843wr9 208 73 ( ( -LRB- cord-035067-ic843wr9 208 74 12 12 CD cord-035067-ic843wr9 208 75 % % NN cord-035067-ic843wr9 208 76 ) ) -RRB- cord-035067-ic843wr9 208 77 , , , cord-035067-ic843wr9 208 78 headache headache NN cord-035067-ic843wr9 208 79 ( ( -LRB- cord-035067-ic843wr9 208 80 9.4 9.4 CD cord-035067-ic843wr9 208 81 % % NN cord-035067-ic843wr9 208 82 ) ) -RRB- cord-035067-ic843wr9 208 83 , , , cord-035067-ic843wr9 208 84 and and CC cord-035067-ic843wr9 208 85 diarrhea diarrhea NN cord-035067-ic843wr9 208 86 ( ( -LRB- cord-035067-ic843wr9 208 87 6.8 6.8 CD cord-035067-ic843wr9 208 88 % % NN cord-035067-ic843wr9 208 89 ) ) -RRB- cord-035067-ic843wr9 208 90 . . . cord-035067-ic843wr9 209 1 The the DT cord-035067-ic843wr9 209 2 incidence incidence NN cord-035067-ic843wr9 209 3 of of IN cord-035067-ic843wr9 209 4 ICU ICU NNP cord-035067-ic843wr9 209 5 use use NN cord-035067-ic843wr9 209 6 , , , cord-035067-ic843wr9 209 7 SARS SARS NNP cord-035067-ic843wr9 209 8 , , , cord-035067-ic843wr9 209 9 multiple multiple JJ cord-035067-ic843wr9 209 10 organ organ NN cord-035067-ic843wr9 209 11 failure failure NN cord-035067-ic843wr9 209 12 , , , cord-035067-ic843wr9 209 13 and and CC cord-035067-ic843wr9 209 14 mortality mortality NN cord-035067-ic843wr9 209 15 was be VBD cord-035067-ic843wr9 209 16 29.3 29.3 CD cord-035067-ic843wr9 209 17 % % NN cord-035067-ic843wr9 209 18 , , , cord-035067-ic843wr9 209 19 28.8 28.8 CD cord-035067-ic843wr9 209 20 % % NN cord-035067-ic843wr9 209 21 , , , cord-035067-ic843wr9 209 22 8.5 8.5 CD cord-035067-ic843wr9 209 23 % % NN cord-035067-ic843wr9 209 24 , , , cord-035067-ic843wr9 209 25 and and CC cord-035067-ic843wr9 209 26 6.8 6.8 CD cord-035067-ic843wr9 209 27 % % NN cord-035067-ic843wr9 209 28 , , , cord-035067-ic843wr9 209 29 respectively respectively RB cord-035067-ic843wr9 209 30 . . . cord-035067-ic843wr9 210 1 The the DT cord-035067-ic843wr9 210 2 limitations limitation NNS cord-035067-ic843wr9 210 3 of of IN cord-035067-ic843wr9 210 4 these these DT cord-035067-ic843wr9 210 5 studies study NNS cord-035067-ic843wr9 210 6 were be VBD cord-035067-ic843wr9 210 7 no no DT cord-035067-ic843wr9 210 8 foreigners foreigner NNS cord-035067-ic843wr9 210 9 included include VBN cord-035067-ic843wr9 210 10 and and CC cord-035067-ic843wr9 210 11 no no DT cord-035067-ic843wr9 210 12 comments comment NNS cord-035067-ic843wr9 210 13 on on IN cord-035067-ic843wr9 210 14 viral viral JJ cord-035067-ic843wr9 210 15 presence presence NN cord-035067-ic843wr9 210 16 in in IN cord-035067-ic843wr9 210 17 the the DT cord-035067-ic843wr9 210 18 feces fece NNS cord-035067-ic843wr9 210 19 . . . cord-035067-ic843wr9 211 1 ( ( -LRB- cord-035067-ic843wr9 211 2 28 28 CD cord-035067-ic843wr9 211 3 ) ) -RRB- cord-035067-ic843wr9 212 1 The the DT cord-035067-ic843wr9 212 2 meta meta JJ cord-035067-ic843wr9 212 3 - - HYPH cord-035067-ic843wr9 212 4 analysis analysis NN cord-035067-ic843wr9 212 5 made make VBN cord-035067-ic843wr9 212 6 by by IN cord-035067-ic843wr9 212 7 Li Li NNP cord-035067-ic843wr9 212 8 et et NNP cord-035067-ic843wr9 212 9 al al NNP cord-035067-ic843wr9 212 10 . . NNP cord-035067-ic843wr9 212 11 , , , cord-035067-ic843wr9 212 12 with with IN cord-035067-ic843wr9 212 13 10 10 CD cord-035067-ic843wr9 212 14 articles article NNS cord-035067-ic843wr9 212 15 and and CC cord-035067-ic843wr9 212 16 1,994 1,994 CD cord-035067-ic843wr9 212 17 patients patient NNS cord-035067-ic843wr9 212 18 from from IN cord-035067-ic843wr9 212 19 China China NNP cord-035067-ic843wr9 212 20 , , , cord-035067-ic843wr9 212 21 showed show VBD cord-035067-ic843wr9 212 22 similar similar JJ cord-035067-ic843wr9 212 23 results result NNS cord-035067-ic843wr9 212 24 . . . cord-035067-ic843wr9 213 1 The the DT cord-035067-ic843wr9 213 2 main main JJ cord-035067-ic843wr9 213 3 symptoms symptom NNS cord-035067-ic843wr9 213 4 reported report VBN cord-035067-ic843wr9 213 5 were be VBD cord-035067-ic843wr9 213 6 fever fever NN cord-035067-ic843wr9 213 7 ( ( -LRB- cord-035067-ic843wr9 213 8 88.5 88.5 CD cord-035067-ic843wr9 213 9 % % NN cord-035067-ic843wr9 213 10 ) ) -RRB- cord-035067-ic843wr9 213 11 , , , cord-035067-ic843wr9 213 12 cough cough NN cord-035067-ic843wr9 213 13 ( ( -LRB- cord-035067-ic843wr9 213 14 68.6 68.6 CD cord-035067-ic843wr9 213 15 % % NN cord-035067-ic843wr9 213 16 ) ) -RRB- cord-035067-ic843wr9 213 17 , , , cord-035067-ic843wr9 213 18 myalgia myalgia NN cord-035067-ic843wr9 213 19 or or CC cord-035067-ic843wr9 213 20 fatigue fatigue NN cord-035067-ic843wr9 213 21 ( ( -LRB- cord-035067-ic843wr9 213 22 35.8 35.8 CD cord-035067-ic843wr9 213 23 % % NN cord-035067-ic843wr9 213 24 ) ) -RRB- cord-035067-ic843wr9 213 25 , , , cord-035067-ic843wr9 213 26 productive productive JJ cord-035067-ic843wr9 213 27 cough cough NN cord-035067-ic843wr9 213 28 ( ( -LRB- cord-035067-ic843wr9 213 29 28.2 28.2 CD cord-035067-ic843wr9 213 30 % % NN cord-035067-ic843wr9 213 31 ) ) -RRB- cord-035067-ic843wr9 213 32 , , , cord-035067-ic843wr9 213 33 and and CC cord-035067-ic843wr9 213 34 dyspnea dyspnea NN cord-035067-ic843wr9 213 35 ( ( -LRB- cord-035067-ic843wr9 213 36 21.9 21.9 CD cord-035067-ic843wr9 213 37 % % NN cord-035067-ic843wr9 213 38 ) ) -RRB- cord-035067-ic843wr9 213 39 . . . cord-035067-ic843wr9 214 1 Other other JJ cord-035067-ic843wr9 214 2 symptoms symptom NNS cord-035067-ic843wr9 214 3 were be VBD cord-035067-ic843wr9 214 4 headache headache NN cord-035067-ic843wr9 214 5 or or CC cord-035067-ic843wr9 214 6 dizziness dizziness NN cord-035067-ic843wr9 214 7 ( ( -LRB- cord-035067-ic843wr9 214 8 12.1 12.1 CD cord-035067-ic843wr9 214 9 % % NN cord-035067-ic843wr9 214 10 ) ) -RRB- cord-035067-ic843wr9 214 11 , , , cord-035067-ic843wr9 214 12 diarrhea diarrhea NN cord-035067-ic843wr9 214 13 ( ( -LRB- cord-035067-ic843wr9 214 14 4.8 4.8 CD cord-035067-ic843wr9 214 15 % % NN cord-035067-ic843wr9 214 16 ) ) -RRB- cord-035067-ic843wr9 214 17 , , , cord-035067-ic843wr9 214 18 and and CC cord-035067-ic843wr9 214 19 nausea nausea NN cord-035067-ic843wr9 214 20 and and CC cord-035067-ic843wr9 214 21 vomiting vomiting NN cord-035067-ic843wr9 214 22 ( ( -LRB- cord-035067-ic843wr9 214 23 3.9 3.9 CD cord-035067-ic843wr9 214 24 % % NN cord-035067-ic843wr9 214 25 ) ) -RRB- cord-035067-ic843wr9 214 26 . . . cord-035067-ic843wr9 215 1 Lymphopenia Lymphopenia NNP cord-035067-ic843wr9 215 2 ( ( -LRB- cord-035067-ic843wr9 215 3 64.5 64.5 CD cord-035067-ic843wr9 215 4 % % NN cord-035067-ic843wr9 215 5 ) ) -RRB- cord-035067-ic843wr9 215 6 , , , cord-035067-ic843wr9 215 7 increased increase VBN cord-035067-ic843wr9 215 8 C c NN cord-035067-ic843wr9 215 9 - - HYPH cord-035067-ic843wr9 215 10 reactive reactive JJ cord-035067-ic843wr9 215 11 protein protein NN cord-035067-ic843wr9 215 12 ( ( -LRB- cord-035067-ic843wr9 215 13 44.3 44.3 CD cord-035067-ic843wr9 215 14 % % NN cord-035067-ic843wr9 215 15 ) ) -RRB- cord-035067-ic843wr9 215 16 , , , cord-035067-ic843wr9 215 17 increased increase VBN cord-035067-ic843wr9 215 18 lactate lactate NN cord-035067-ic843wr9 215 19 dehydrogenase dehydrogenase NN cord-035067-ic843wr9 215 20 ( ( -LRB- cord-035067-ic843wr9 215 21 28.3 28.3 CD cord-035067-ic843wr9 215 22 % % NN cord-035067-ic843wr9 215 23 ) ) -RRB- cord-035067-ic843wr9 215 24 , , , cord-035067-ic843wr9 215 25 and and CC cord-035067-ic843wr9 215 26 leukopenia leukopenia NN cord-035067-ic843wr9 215 27 ( ( -LRB- cord-035067-ic843wr9 215 28 29.4 29.4 CD cord-035067-ic843wr9 215 29 % % NN cord-035067-ic843wr9 215 30 ) ) -RRB- cord-035067-ic843wr9 215 31 were be VBD cord-035067-ic843wr9 215 32 also also RB cord-035067-ic843wr9 215 33 recorded record VBN cord-035067-ic843wr9 215 34 . . . cord-035067-ic843wr9 216 1 In in IN cord-035067-ic843wr9 216 2 addition addition NN cord-035067-ic843wr9 216 3 , , , cord-035067-ic843wr9 216 4 men man NNS cord-035067-ic843wr9 216 5 were be VBD cord-035067-ic843wr9 216 6 more more RBR cord-035067-ic843wr9 216 7 affected affected JJ cord-035067-ic843wr9 216 8 ( ( -LRB- cord-035067-ic843wr9 216 9 60 60 CD cord-035067-ic843wr9 216 10 % % NN cord-035067-ic843wr9 216 11 ) ) -RRB- cord-035067-ic843wr9 216 12 , , , cord-035067-ic843wr9 216 13 and and CC cord-035067-ic843wr9 216 14 the the DT cord-035067-ic843wr9 216 15 fatality fatality NN cord-035067-ic843wr9 216 16 rate rate NN cord-035067-ic843wr9 216 17 was be VBD cord-035067-ic843wr9 216 18 5 5 CD cord-035067-ic843wr9 216 19 % % NN cord-035067-ic843wr9 216 20 . . . cord-035067-ic843wr9 217 1 This this DT cord-035067-ic843wr9 217 2 study study NN cord-035067-ic843wr9 217 3 presented present VBD cord-035067-ic843wr9 217 4 limitations limitation NNS cord-035067-ic843wr9 217 5 by by IN cord-035067-ic843wr9 217 6 the the DT cord-035067-ic843wr9 217 7 number number NN cord-035067-ic843wr9 217 8 and and CC cord-035067-ic843wr9 217 9 quality quality NN cord-035067-ic843wr9 217 10 of of IN cord-035067-ic843wr9 217 11 studies study NNS cord-035067-ic843wr9 217 12 included include VBN cord-035067-ic843wr9 217 13 . . . cord-035067-ic843wr9 218 1 ( ( -LRB- cord-035067-ic843wr9 218 2 29 29 CD cord-035067-ic843wr9 218 3 ) ) -RRB- cord-035067-ic843wr9 219 1 Sultan Sultan NNP cord-035067-ic843wr9 219 2 et et NNP cord-035067-ic843wr9 219 3 al al NNP cord-035067-ic843wr9 219 4 . . NNP cord-035067-ic843wr9 219 5 , , , cord-035067-ic843wr9 219 6 performed perform VBD cord-035067-ic843wr9 219 7 a a DT cord-035067-ic843wr9 219 8 systematic systematic JJ cord-035067-ic843wr9 219 9 review review NN cord-035067-ic843wr9 219 10 and and CC cord-035067-ic843wr9 219 11 meta meta NNP cord-035067-ic843wr9 219 12 - - HYPH cord-035067-ic843wr9 219 13 analysis analysis NN cord-035067-ic843wr9 219 14 of of IN cord-035067-ic843wr9 219 15 47 47 CD cord-035067-ic843wr9 219 16 studies study NNS cord-035067-ic843wr9 219 17 with with IN cord-035067-ic843wr9 219 18 10,890 10,890 CD cord-035067-ic843wr9 219 19 patients patient NNS cord-035067-ic843wr9 219 20 . . . cord-035067-ic843wr9 220 1 The the DT cord-035067-ic843wr9 220 2 prevalence prevalence NN cord-035067-ic843wr9 220 3 of of IN cord-035067-ic843wr9 220 4 diarrhea diarrhea NN cord-035067-ic843wr9 220 5 was be VBD cord-035067-ic843wr9 220 6 7.7 7.7 CD cord-035067-ic843wr9 220 7 % % NN cord-035067-ic843wr9 220 8 , , , cord-035067-ic843wr9 220 9 nausea nausea NN cord-035067-ic843wr9 220 10 and and CC cord-035067-ic843wr9 220 11 vomiting vomit VBG cord-035067-ic843wr9 220 12 7.8 7.8 CD cord-035067-ic843wr9 220 13 % % NN cord-035067-ic843wr9 220 14 , , , cord-035067-ic843wr9 220 15 and and CC cord-035067-ic843wr9 220 16 abdominal abdominal JJ cord-035067-ic843wr9 220 17 pain pain NN cord-035067-ic843wr9 220 18 2.7 2.7 CD cord-035067-ic843wr9 220 19 % % NN cord-035067-ic843wr9 220 20 . . . cord-035067-ic843wr9 221 1 When when WRB cord-035067-ic843wr9 221 2 comparing compare VBG cord-035067-ic843wr9 221 3 data datum NNS cord-035067-ic843wr9 221 4 from from IN cord-035067-ic843wr9 221 5 China China NNP cord-035067-ic843wr9 221 6 and and CC cord-035067-ic843wr9 221 7 other other JJ cord-035067-ic843wr9 221 8 countries country NNS cord-035067-ic843wr9 221 9 , , , cord-035067-ic843wr9 221 10 diarrhea diarrhea NN cord-035067-ic843wr9 221 11 ( ( -LRB- cord-035067-ic843wr9 221 12 5.8 5.8 CD cord-035067-ic843wr9 221 13 % % NN cord-035067-ic843wr9 221 14 versus versus IN cord-035067-ic843wr9 221 15 18.3 18.3 CD cord-035067-ic843wr9 221 16 % % NN cord-035067-ic843wr9 221 17 ) ) -RRB- cord-035067-ic843wr9 221 18 , , , cord-035067-ic843wr9 221 19 nausea nausea NN cord-035067-ic843wr9 221 20 and and CC cord-035067-ic843wr9 221 21 vomiting vomiting NN cord-035067-ic843wr9 221 22 ( ( -LRB- cord-035067-ic843wr9 221 23 5.2 5.2 CD cord-035067-ic843wr9 221 24 % % NN cord-035067-ic843wr9 221 25 versus versus IN cord-035067-ic843wr9 221 26 14.9 14.9 CD cord-035067-ic843wr9 221 27 % % NN cord-035067-ic843wr9 221 28 ) ) -RRB- cord-035067-ic843wr9 221 29 , , , cord-035067-ic843wr9 221 30 abdominal abdominal JJ cord-035067-ic843wr9 221 31 pain pain NN cord-035067-ic843wr9 221 32 ( ( -LRB- cord-035067-ic843wr9 221 33 2.7 2.7 CD cord-035067-ic843wr9 221 34 % % NN cord-035067-ic843wr9 221 35 versus versus IN cord-035067-ic843wr9 221 36 5.3 5.3 CD cord-035067-ic843wr9 221 37 % % NN cord-035067-ic843wr9 221 38 ) ) -RRB- cord-035067-ic843wr9 221 39 , , , cord-035067-ic843wr9 221 40 and and CC cord-035067-ic843wr9 221 41 liver liver NN cord-035067-ic843wr9 221 42 abnormalities abnormality NNS cord-035067-ic843wr9 221 43 were be VBD cord-035067-ic843wr9 221 44 more more RBR cord-035067-ic843wr9 221 45 prevalent prevalent JJ cord-035067-ic843wr9 221 46 outside outside IN cord-035067-ic843wr9 221 47 China China NNP cord-035067-ic843wr9 221 48 . . . cord-035067-ic843wr9 222 1 The the DT cord-035067-ic843wr9 222 2 liver liver NN cord-035067-ic843wr9 222 3 alterations alteration NNS cord-035067-ic843wr9 222 4 studied study VBD cord-035067-ic843wr9 222 5 were be VBD cord-035067-ic843wr9 222 6 AST AST NNP cord-035067-ic843wr9 222 7 elevation elevation NN cord-035067-ic843wr9 222 8 ( ( -LRB- cord-035067-ic843wr9 222 9 total total NN cord-035067-ic843wr9 222 10 : : : cord-035067-ic843wr9 222 11 15.0 15.0 CD cord-035067-ic843wr9 222 12 % % NN cord-035067-ic843wr9 222 13 ; ; : cord-035067-ic843wr9 222 14 China China NNP cord-035067-ic843wr9 222 15 : : : cord-035067-ic843wr9 222 16 14.9 14.9 CD cord-035067-ic843wr9 222 17 % % NN cord-035067-ic843wr9 222 18 ; ; , cord-035067-ic843wr9 222 19 other other JJ cord-035067-ic843wr9 222 20 countries country NNS cord-035067-ic843wr9 222 21 : : : cord-035067-ic843wr9 222 22 20.0 20.0 CD cord-035067-ic843wr9 222 23 % % NN cord-035067-ic843wr9 222 24 ) ) -RRB- cord-035067-ic843wr9 222 25 , , , cord-035067-ic843wr9 222 26 ALT ALT NNP cord-035067-ic843wr9 222 27 ( ( -LRB- cord-035067-ic843wr9 222 28 total total NN cord-035067-ic843wr9 222 29 : : : cord-035067-ic843wr9 222 30 15.0 15.0 CD cord-035067-ic843wr9 222 31 % % NN cord-035067-ic843wr9 222 32 ; ; : cord-035067-ic843wr9 222 33 China China NNP cord-035067-ic843wr9 222 34 : : : cord-035067-ic843wr9 222 35 14.9 14.9 CD cord-035067-ic843wr9 222 36 % % NN cord-035067-ic843wr9 222 37 ; ; , cord-035067-ic843wr9 222 38 other other JJ cord-035067-ic843wr9 222 39 countries country NNS cord-035067-ic843wr9 222 40 : : : cord-035067-ic843wr9 222 41 19.0 19.0 CD cord-035067-ic843wr9 222 42 % % NN cord-035067-ic843wr9 222 43 ) ) -RRB- cord-035067-ic843wr9 222 44 , , , cord-035067-ic843wr9 222 45 and and CC cord-035067-ic843wr9 222 46 bilirubin bilirubin JJ cord-035067-ic843wr9 222 47 ( ( -LRB- cord-035067-ic843wr9 222 48 total total NN cord-035067-ic843wr9 222 49 or or CC cord-035067-ic843wr9 222 50 China China NNP cord-035067-ic843wr9 222 51 : : : cord-035067-ic843wr9 222 52 16.7 16.7 CD cord-035067-ic843wr9 222 53 % % NN cord-035067-ic843wr9 222 54 ) ) -RRB- cord-035067-ic843wr9 222 55 . . . cord-035067-ic843wr9 223 1 There there EX cord-035067-ic843wr9 223 2 was be VBD cord-035067-ic843wr9 223 3 no no DT cord-035067-ic843wr9 223 4 deeper deep JJR cord-035067-ic843wr9 223 5 analysis analysis NN cord-035067-ic843wr9 223 6 about about IN cord-035067-ic843wr9 223 7 the the DT cord-035067-ic843wr9 223 8 presence presence NN cord-035067-ic843wr9 223 9 of of IN cord-035067-ic843wr9 223 10 viral viral JJ cord-035067-ic843wr9 223 11 RNA RNA NNP cord-035067-ic843wr9 223 12 in in IN cord-035067-ic843wr9 223 13 the the DT cord-035067-ic843wr9 223 14 feces fece NNS cord-035067-ic843wr9 223 15 of of IN cord-035067-ic843wr9 223 16 these these DT cord-035067-ic843wr9 223 17 patients patient NNS cord-035067-ic843wr9 223 18 , , , cord-035067-ic843wr9 223 19 but but CC cord-035067-ic843wr9 223 20 the the DT cord-035067-ic843wr9 223 21 authors author NNS cord-035067-ic843wr9 223 22 found find VBD cord-035067-ic843wr9 223 23 a a DT cord-035067-ic843wr9 223 24 variable variable JJ cord-035067-ic843wr9 223 25 prevalence prevalence NN cord-035067-ic843wr9 223 26 of of IN cord-035067-ic843wr9 223 27 15/50 15/50 CD cord-035067-ic843wr9 223 28 ( ( -LRB- cord-035067-ic843wr9 223 29 30 30 CD cord-035067-ic843wr9 223 30 % % NN cord-035067-ic843wr9 223 31 ) ) -RRB- cord-035067-ic843wr9 223 32 , , , cord-035067-ic843wr9 223 33 7/10 7/10 CD cord-035067-ic843wr9 223 34 ( ( -LRB- cord-035067-ic843wr9 223 35 70 70 CD cord-035067-ic843wr9 223 36 % % NN cord-035067-ic843wr9 223 37 ) ) -RRB- cord-035067-ic843wr9 223 38 , , , cord-035067-ic843wr9 223 39 and and CC cord-035067-ic843wr9 223 40 44/153 44/153 CD cord-035067-ic843wr9 223 41 ( ( -LRB- cord-035067-ic843wr9 223 42 29 29 CD cord-035067-ic843wr9 223 43 % % NN cord-035067-ic843wr9 223 44 ) ) -RRB- cord-035067-ic843wr9 223 45 . . . cord-035067-ic843wr9 224 1 The the DT cord-035067-ic843wr9 224 2 authors author NNS cord-035067-ic843wr9 224 3 also also RB cord-035067-ic843wr9 224 4 provided provide VBD cord-035067-ic843wr9 224 5 a a DT cord-035067-ic843wr9 224 6 manual manual NN cord-035067-ic843wr9 224 7 of of IN cord-035067-ic843wr9 224 8 recommendations recommendation NNS cord-035067-ic843wr9 224 9 for for IN cord-035067-ic843wr9 224 10 good good JJ cord-035067-ic843wr9 224 11 practices practice NNS cord-035067-ic843wr9 224 12 in in IN cord-035067-ic843wr9 224 13 the the DT cord-035067-ic843wr9 224 14 management management NN cord-035067-ic843wr9 224 15 of of IN cord-035067-ic843wr9 224 16 COVID-19 COVID-19 NNP cord-035067-ic843wr9 224 17 with with IN cord-035067-ic843wr9 224 18 seven seven CD cord-035067-ic843wr9 224 19 items item NNS cord-035067-ic843wr9 224 20 ; ; : cord-035067-ic843wr9 224 21 the the DT cord-035067-ic843wr9 224 22 main main JJ cord-035067-ic843wr9 224 23 points point NNS cord-035067-ic843wr9 224 24 are be VBP cord-035067-ic843wr9 224 25 to to TO cord-035067-ic843wr9 224 26 obtain obtain VB cord-035067-ic843wr9 224 27 a a DT cord-035067-ic843wr9 224 28 detailed detailed JJ cord-035067-ic843wr9 224 29 history history NN cord-035067-ic843wr9 224 30 of of IN cord-035067-ic843wr9 224 31 symptoms symptom NNS cord-035067-ic843wr9 224 32 ( ( -LRB- cord-035067-ic843wr9 224 33 typical typical JJ cord-035067-ic843wr9 224 34 and and CC cord-035067-ic843wr9 224 35 GIT GIT NNP cord-035067-ic843wr9 224 36 ) ) -RRB- cord-035067-ic843wr9 224 37 , , , cord-035067-ic843wr9 224 38 to to TO cord-035067-ic843wr9 224 39 verify verify VB cord-035067-ic843wr9 224 40 liver liver NN cord-035067-ic843wr9 224 41 function function NN cord-035067-ic843wr9 224 42 values value NNS cord-035067-ic843wr9 224 43 upon upon IN cord-035067-ic843wr9 224 44 admission admission NN cord-035067-ic843wr9 224 45 of of IN cord-035067-ic843wr9 224 46 patients patient NNS cord-035067-ic843wr9 224 47 and and CC cord-035067-ic843wr9 224 48 monitor monitor VB cord-035067-ic843wr9 224 49 during during IN cord-035067-ic843wr9 224 50 hospitalization hospitalization NN cord-035067-ic843wr9 224 51 , , , cord-035067-ic843wr9 224 52 and and CC cord-035067-ic843wr9 224 53 to to TO cord-035067-ic843wr9 224 54 evaluate evaluate VB cord-035067-ic843wr9 224 55 the the DT cord-035067-ic843wr9 224 56 adverse adverse JJ cord-035067-ic843wr9 224 57 reactions reaction NNS cord-035067-ic843wr9 224 58 of of IN cord-035067-ic843wr9 224 59 drugs drug NNS cord-035067-ic843wr9 224 60 used use VBN cord-035067-ic843wr9 224 61 in in IN cord-035067-ic843wr9 224 62 treatment treatment NN cord-035067-ic843wr9 224 63 . . . cord-035067-ic843wr9 225 1 Regarding regard VBG cord-035067-ic843wr9 225 2 limitations limitation NNS cord-035067-ic843wr9 225 3 , , , cord-035067-ic843wr9 225 4 the the DT cord-035067-ic843wr9 225 5 patients patient NNS cord-035067-ic843wr9 225 6 were be VBD cord-035067-ic843wr9 225 7 hospitalized hospitalize VBN cord-035067-ic843wr9 225 8 ( ( -LRB- cord-035067-ic843wr9 225 9 prevalence prevalence NN cord-035067-ic843wr9 225 10 may may MD cord-035067-ic843wr9 225 11 be be VB cord-035067-ic843wr9 225 12 under under IN cord-035067-ic843wr9 225 13 or or CC cord-035067-ic843wr9 225 14 overestimated overestimated JJ cord-035067-ic843wr9 225 15 ) ) -RRB- cord-035067-ic843wr9 225 16 , , , cord-035067-ic843wr9 225 17 the the DT cord-035067-ic843wr9 225 18 symptoms symptom NNS cord-035067-ic843wr9 225 19 may may MD cord-035067-ic843wr9 225 20 have have VB cord-035067-ic843wr9 225 21 been be VBN cord-035067-ic843wr9 225 22 analyzed analyze VBN cord-035067-ic843wr9 225 23 inconsistently inconsistently RB cord-035067-ic843wr9 225 24 , , , cord-035067-ic843wr9 225 25 information information NN cord-035067-ic843wr9 225 26 from from IN cord-035067-ic843wr9 225 27 laboratory laboratory NN cord-035067-ic843wr9 225 28 tests test NNS cord-035067-ic843wr9 225 29 was be VBD cord-035067-ic843wr9 225 30 lacking lack VBG cord-035067-ic843wr9 225 31 , , , cord-035067-ic843wr9 225 32 and and CC cord-035067-ic843wr9 225 33 there there EX cord-035067-ic843wr9 225 34 was be VBD cord-035067-ic843wr9 225 35 no no DT cord-035067-ic843wr9 225 36 information information NN cord-035067-ic843wr9 225 37 about about IN cord-035067-ic843wr9 225 38 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 225 39 symptoms symptom NNS cord-035067-ic843wr9 225 40 being be VBG cord-035067-ic843wr9 225 41 systematically systematically RB cord-035067-ic843wr9 225 42 evaluated evaluate VBN cord-035067-ic843wr9 225 43 at at IN cord-035067-ic843wr9 225 44 admission admission NN cord-035067-ic843wr9 225 45 , , , cord-035067-ic843wr9 225 46 among among IN cord-035067-ic843wr9 225 47 others other NNS cord-035067-ic843wr9 225 48 . . . cord-035067-ic843wr9 226 1 They -PRON- PRP cord-035067-ic843wr9 226 2 concluded conclude VBD cord-035067-ic843wr9 226 3 hepatic hepatic JJ cord-035067-ic843wr9 226 4 enzyme enzyme NN cord-035067-ic843wr9 226 5 monitoring monitoring NN cord-035067-ic843wr9 226 6 may may MD cord-035067-ic843wr9 226 7 be be VB cord-035067-ic843wr9 226 8 beneficial beneficial JJ cord-035067-ic843wr9 226 9 , , , cord-035067-ic843wr9 226 10 and and CC cord-035067-ic843wr9 226 11 there there EX cord-035067-ic843wr9 226 12 is be VBZ cord-035067-ic843wr9 226 13 still still RB cord-035067-ic843wr9 226 14 no no DT cord-035067-ic843wr9 226 15 evidence evidence NN cord-035067-ic843wr9 226 16 to to TO cord-035067-ic843wr9 226 17 support support VB cord-035067-ic843wr9 226 18 the the DT cord-035067-ic843wr9 226 19 viral viral JJ cord-035067-ic843wr9 226 20 PCR PCR NNP cord-035067-ic843wr9 226 21 test test NN cord-035067-ic843wr9 226 22 in in IN cord-035067-ic843wr9 226 23 the the DT cord-035067-ic843wr9 226 24 stools stool NNS cord-035067-ic843wr9 226 25 as as IN cord-035067-ic843wr9 226 26 a a DT cord-035067-ic843wr9 226 27 diagnosis diagnosis NN cord-035067-ic843wr9 226 28 or or CC cord-035067-ic843wr9 226 29 for for IN cord-035067-ic843wr9 226 30 monitoring monitoring NN cord-035067-ic843wr9 226 31 of of IN cord-035067-ic843wr9 226 32 COVID-19 COVID-19 NNP cord-035067-ic843wr9 226 33 as as IN cord-035067-ic843wr9 226 34 a a DT cord-035067-ic843wr9 226 35 routine routine NN cord-035067-ic843wr9 226 36 in in IN cord-035067-ic843wr9 226 37 clinical clinical JJ cord-035067-ic843wr9 226 38 practice practice NN cord-035067-ic843wr9 226 39 , , , cord-035067-ic843wr9 226 40 because because IN cord-035067-ic843wr9 226 41 the the DT cord-035067-ic843wr9 226 42 results result NNS cord-035067-ic843wr9 226 43 of of IN cord-035067-ic843wr9 226 44 other other JJ cord-035067-ic843wr9 226 45 meta meta JJ cord-035067-ic843wr9 226 46 - - HYPH cord-035067-ic843wr9 226 47 analyses analysis NNS cord-035067-ic843wr9 226 48 are be VBP cord-035067-ic843wr9 226 49 conflicting conflict VBG cord-035067-ic843wr9 226 50 and and CC cord-035067-ic843wr9 226 51 further further JJ cord-035067-ic843wr9 226 52 studies study NNS cord-035067-ic843wr9 226 53 on on IN cord-035067-ic843wr9 226 54 the the DT cord-035067-ic843wr9 226 55 subject subject NN cord-035067-ic843wr9 226 56 are be VBP cord-035067-ic843wr9 226 57 needed need VBN cord-035067-ic843wr9 226 58 . . . cord-035067-ic843wr9 227 1 ( ( -LRB- cord-035067-ic843wr9 227 2 8) 8) NNP cord-035067-ic843wr9 228 1 ❚ ❚ . cord-035067-ic843wr9 229 1 With with IN cord-035067-ic843wr9 229 2 the the DT cord-035067-ic843wr9 229 3 evaluation evaluation NN cord-035067-ic843wr9 229 4 of of IN cord-035067-ic843wr9 229 5 all all PDT cord-035067-ic843wr9 229 6 these these DT cord-035067-ic843wr9 229 7 studies study NNS cord-035067-ic843wr9 229 8 , , , cord-035067-ic843wr9 229 9 one one PRP cord-035067-ic843wr9 229 10 can can MD cord-035067-ic843wr9 229 11 see see VB cord-035067-ic843wr9 229 12 that that IN cord-035067-ic843wr9 229 13 there there EX cord-035067-ic843wr9 229 14 is be VBZ cord-035067-ic843wr9 229 15 still still RB cord-035067-ic843wr9 229 16 a a DT cord-035067-ic843wr9 229 17 lot lot NN cord-035067-ic843wr9 229 18 of of IN cord-035067-ic843wr9 229 19 variation variation NN cord-035067-ic843wr9 229 20 in in IN cord-035067-ic843wr9 229 21 the the DT cord-035067-ic843wr9 229 22 results result NNS cord-035067-ic843wr9 229 23 regarding regard VBG cord-035067-ic843wr9 229 24 several several JJ cord-035067-ic843wr9 229 25 points point NNS cord-035067-ic843wr9 229 26 , , , cord-035067-ic843wr9 229 27 and and CC cord-035067-ic843wr9 229 28 the the DT cord-035067-ic843wr9 229 29 factors factor NNS cord-035067-ic843wr9 229 30 studied study VBN cord-035067-ic843wr9 229 31 were be VBD cord-035067-ic843wr9 229 32 very very RB cord-035067-ic843wr9 229 33 different different JJ cord-035067-ic843wr9 229 34 . . . cord-035067-ic843wr9 230 1 The the DT cord-035067-ic843wr9 230 2 mean mean JJ cord-035067-ic843wr9 230 3 age age NN cord-035067-ic843wr9 230 4 of of IN cord-035067-ic843wr9 230 5 patients patient NNS cord-035067-ic843wr9 230 6 ranged range VBD cord-035067-ic843wr9 230 7 from from IN cord-035067-ic843wr9 230 8 45.1 45.1 CD cord-035067-ic843wr9 230 9 to to IN cord-035067-ic843wr9 230 10 58.5 58.5 CD cord-035067-ic843wr9 230 11 years year NNS cord-035067-ic843wr9 230 12 , , , cord-035067-ic843wr9 230 13 but but CC cord-035067-ic843wr9 230 14 only only RB cord-035067-ic843wr9 230 15 one one CD cord-035067-ic843wr9 230 16 article article NN cord-035067-ic843wr9 230 17 significantly significantly RB cord-035067-ic843wr9 230 18 correlated correlate VBD cord-035067-ic843wr9 230 19 advanced advanced JJ cord-035067-ic843wr9 230 20 age age NN cord-035067-ic843wr9 230 21 with with IN cord-035067-ic843wr9 230 22 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 230 23 symptoms symptom NNS cord-035067-ic843wr9 230 24 . . . cord-035067-ic843wr9 231 1 ( ( -LRB- cord-035067-ic843wr9 231 2 21 21 CD cord-035067-ic843wr9 231 3 ) ) -RRB- cord-035067-ic843wr9 232 1 In in IN cord-035067-ic843wr9 232 2 another another DT cord-035067-ic843wr9 232 3 article article NN cord-035067-ic843wr9 232 4 , , , cord-035067-ic843wr9 232 5 advanced advanced JJ cord-035067-ic843wr9 232 6 age age NN cord-035067-ic843wr9 232 7 was be VBD cord-035067-ic843wr9 232 8 related relate VBN cord-035067-ic843wr9 232 9 to to IN cord-035067-ic843wr9 232 10 severity severity NN cord-035067-ic843wr9 232 11 of of IN cord-035067-ic843wr9 232 12 the the DT cord-035067-ic843wr9 232 13 disease disease NN cord-035067-ic843wr9 232 14 , , , cord-035067-ic843wr9 232 15 but but CC cord-035067-ic843wr9 232 16 without without IN cord-035067-ic843wr9 232 17 assessing assess VBG cord-035067-ic843wr9 232 18 whether whether IN cord-035067-ic843wr9 232 19 these these DT cord-035067-ic843wr9 232 20 patients patient NNS cord-035067-ic843wr9 232 21 had have VBD cord-035067-ic843wr9 232 22 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 232 23 symptoms symptom NNS cord-035067-ic843wr9 232 24 . . . cord-035067-ic843wr9 233 1 ( ( -LRB- cord-035067-ic843wr9 233 2 25 25 CD cord-035067-ic843wr9 233 3 ) ) -RRB- cord-035067-ic843wr9 234 1 In in IN cord-035067-ic843wr9 234 2 general general JJ cord-035067-ic843wr9 234 3 , , , cord-035067-ic843wr9 234 4 all all DT cord-035067-ic843wr9 234 5 articles article NNS cord-035067-ic843wr9 234 6 found find VBD cord-035067-ic843wr9 234 7 more more JJR cord-035067-ic843wr9 234 8 men man NNS cord-035067-ic843wr9 234 9 affected affect VBN cord-035067-ic843wr9 234 10 with with IN cord-035067-ic843wr9 234 11 COVID-19 covid-19 CD cord-035067-ic843wr9 234 12 than than IN cord-035067-ic843wr9 234 13 women woman NNS cord-035067-ic843wr9 234 14 , , , cord-035067-ic843wr9 234 15 and and CC cord-035067-ic843wr9 234 16 only only RB cord-035067-ic843wr9 234 17 one one CD cord-035067-ic843wr9 234 18 found find VBD cord-035067-ic843wr9 234 19 a a DT cord-035067-ic843wr9 234 20 significant significant JJ cord-035067-ic843wr9 234 21 difference difference NN cord-035067-ic843wr9 234 22 between between IN cord-035067-ic843wr9 234 23 non non JJ cord-035067-ic843wr9 234 24 - - JJ cord-035067-ic843wr9 234 25 medical medical JJ cord-035067-ic843wr9 234 26 women woman NNS cord-035067-ic843wr9 234 27 and and CC cord-035067-ic843wr9 234 28 more more RBR cord-035067-ic843wr9 234 29 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 234 30 symptoms symptom NNS cord-035067-ic843wr9 234 31 . . . cord-035067-ic843wr9 235 1 ( ( -LRB- cord-035067-ic843wr9 235 2 26 26 CD cord-035067-ic843wr9 235 3 ) ) -RRB- cord-035067-ic843wr9 236 1 These these DT cord-035067-ic843wr9 236 2 results result NNS cord-035067-ic843wr9 236 3 suggested suggest VBD cord-035067-ic843wr9 236 4 that that IN cord-035067-ic843wr9 236 5 advanced advanced JJ cord-035067-ic843wr9 236 6 age age NN cord-035067-ic843wr9 236 7 and and CC cord-035067-ic843wr9 236 8 male male JJ cord-035067-ic843wr9 236 9 gender gender NN cord-035067-ic843wr9 236 10 are be VBP cord-035067-ic843wr9 236 11 risk risk NN cord-035067-ic843wr9 236 12 factors factor NNS cord-035067-ic843wr9 236 13 for for IN cord-035067-ic843wr9 236 14 infection infection NN cord-035067-ic843wr9 236 15 . . . cord-035067-ic843wr9 237 1 The the DT cord-035067-ic843wr9 237 2 ACE2 ACE2 NNP cord-035067-ic843wr9 237 3 receptor receptor NN cord-035067-ic843wr9 237 4 gene gene NN cord-035067-ic843wr9 237 5 , , , cord-035067-ic843wr9 237 6 target target NN cord-035067-ic843wr9 237 7 of of IN cord-035067-ic843wr9 237 8 SARV SARV NNP cord-035067-ic843wr9 237 9 - - HYPH cord-035067-ic843wr9 237 10 CoV-2 CoV-2 NNP cord-035067-ic843wr9 237 11 , , , cord-035067-ic843wr9 237 12 is be VBZ cord-035067-ic843wr9 237 13 located locate VBN cord-035067-ic843wr9 237 14 on on IN cord-035067-ic843wr9 237 15 the the DT cord-035067-ic843wr9 237 16 X x NN cord-035067-ic843wr9 237 17 chromosome chromosome NN cord-035067-ic843wr9 237 18 . . . cord-035067-ic843wr9 238 1 A a DT cord-035067-ic843wr9 238 2 study study NN cord-035067-ic843wr9 238 3 still still RB cord-035067-ic843wr9 238 4 under under IN cord-035067-ic843wr9 238 5 review review NN cord-035067-ic843wr9 238 6 found find VBD cord-035067-ic843wr9 238 7 that that IN cord-035067-ic843wr9 238 8 ACE2 ACE2 NNP cord-035067-ic843wr9 238 9 expression expression NN cord-035067-ic843wr9 238 10 increases increase VBZ cord-035067-ic843wr9 238 11 in in IN cord-035067-ic843wr9 238 12 females female NNS cord-035067-ic843wr9 238 13 and and CC cord-035067-ic843wr9 238 14 with with IN cord-035067-ic843wr9 238 15 sex sex NN cord-035067-ic843wr9 238 16 hormones hormone NNS cord-035067-ic843wr9 238 17 ( ( -LRB- cord-035067-ic843wr9 238 18 which which WDT cord-035067-ic843wr9 238 19 decrease decrease VBP cord-035067-ic843wr9 238 20 with with IN cord-035067-ic843wr9 238 21 ageing age VBG cord-035067-ic843wr9 238 22 ) ) -RRB- cord-035067-ic843wr9 238 23 ; ; : cord-035067-ic843wr9 238 24 additionally additionally RB cord-035067-ic843wr9 238 25 , , , cord-035067-ic843wr9 238 26 inflammatory inflammatory JJ cord-035067-ic843wr9 238 27 cytokines cytokine NNS cord-035067-ic843wr9 238 28 decrease decrease VBP cord-035067-ic843wr9 238 29 this this DT cord-035067-ic843wr9 238 30 expression expression NN cord-035067-ic843wr9 238 31 ( ( -LRB- cord-035067-ic843wr9 238 32 which which WDT cord-035067-ic843wr9 238 33 increase increase NN cord-035067-ic843wr9 238 34 with with IN cord-035067-ic843wr9 238 35 ageing age VBG cord-035067-ic843wr9 238 36 and and CC cord-035067-ic843wr9 238 37 chronic chronic JJ cord-035067-ic843wr9 238 38 diseases disease NNS cord-035067-ic843wr9 238 39 ) ) -RRB- cord-035067-ic843wr9 238 40 . . . cord-035067-ic843wr9 239 1 This this DT cord-035067-ic843wr9 239 2 is be VBZ cord-035067-ic843wr9 239 3 contrary contrary JJ cord-035067-ic843wr9 239 4 to to IN cord-035067-ic843wr9 239 5 what what WP cord-035067-ic843wr9 239 6 is be VBZ cord-035067-ic843wr9 239 7 currently currently RB cord-035067-ic843wr9 239 8 thought think VBN cord-035067-ic843wr9 239 9 , , , cord-035067-ic843wr9 239 10 that that RB cord-035067-ic843wr9 239 11 is is RB cord-035067-ic843wr9 239 12 , , , cord-035067-ic843wr9 239 13 increased increase VBN cord-035067-ic843wr9 239 14 ACE2 ACE2 NNP cord-035067-ic843wr9 239 15 is be VBZ cord-035067-ic843wr9 239 16 to to TO cord-035067-ic843wr9 239 17 be be VB cord-035067-ic843wr9 239 18 blamed blame VBN cord-035067-ic843wr9 239 19 for for IN cord-035067-ic843wr9 239 20 the the DT cord-035067-ic843wr9 239 21 worse bad JJR cord-035067-ic843wr9 239 22 prognosis prognosis NN cord-035067-ic843wr9 239 23 of of IN cord-035067-ic843wr9 239 24 COVID-19 COVID-19 NNP cord-035067-ic843wr9 239 25 . . . cord-035067-ic843wr9 240 1 SARS SARS NNP cord-035067-ic843wr9 240 2 - - HYPH cord-035067-ic843wr9 240 3 CoV-2 CoV-2 NNP cord-035067-ic843wr9 240 4 binds bind VBZ cord-035067-ic843wr9 240 5 directly directly RB cord-035067-ic843wr9 240 6 to to IN cord-035067-ic843wr9 240 7 ACE2 ACE2 NNP cord-035067-ic843wr9 240 8 , , , cord-035067-ic843wr9 240 9 causing cause VBG cord-035067-ic843wr9 240 10 downregulation downregulation NN cord-035067-ic843wr9 240 11 of of IN cord-035067-ic843wr9 240 12 this this DT cord-035067-ic843wr9 240 13 receptor receptor NN cord-035067-ic843wr9 240 14 , , , cord-035067-ic843wr9 240 15 which which WDT cord-035067-ic843wr9 240 16 is be VBZ cord-035067-ic843wr9 240 17 even even RB cord-035067-ic843wr9 240 18 less less JJR cord-035067-ic843wr9 240 19 in in IN cord-035067-ic843wr9 240 20 males male NNS cord-035067-ic843wr9 240 21 , , , cord-035067-ic843wr9 240 22 for for IN cord-035067-ic843wr9 240 23 example example NN cord-035067-ic843wr9 240 24 , , , cord-035067-ic843wr9 240 25 and and CC cord-035067-ic843wr9 240 26 may may MD cord-035067-ic843wr9 240 27 explain explain VB cord-035067-ic843wr9 240 28 the the DT cord-035067-ic843wr9 240 29 worse bad JJR cord-035067-ic843wr9 240 30 prognosis prognosis NN cord-035067-ic843wr9 240 31 and and CC cord-035067-ic843wr9 240 32 the the DT cord-035067-ic843wr9 240 33 more more RBR cord-035067-ic843wr9 240 34 prevalent prevalent JJ cord-035067-ic843wr9 240 35 infection infection NN cord-035067-ic843wr9 240 36 in in IN cord-035067-ic843wr9 240 37 them -PRON- PRP cord-035067-ic843wr9 240 38 . . . cord-035067-ic843wr9 241 1 ( ( -LRB- cord-035067-ic843wr9 241 2 31 31 CD cord-035067-ic843wr9 241 3 ) ) -RRB- cord-035067-ic843wr9 242 1 Regarding regard VBG cord-035067-ic843wr9 242 2 the the DT cord-035067-ic843wr9 242 3 comorbidities comorbiditie NNS cord-035067-ic843wr9 242 4 of of IN cord-035067-ic843wr9 242 5 infected infected JJ cord-035067-ic843wr9 242 6 patients patient NNS cord-035067-ic843wr9 242 7 , , , cord-035067-ic843wr9 242 8 the the DT cord-035067-ic843wr9 242 9 most most RBS cord-035067-ic843wr9 242 10 often often RB cord-035067-ic843wr9 242 11 cited cite VBN cord-035067-ic843wr9 242 12 were be VBD cord-035067-ic843wr9 242 13 hypertension hypertension NN cord-035067-ic843wr9 242 14 , , , cord-035067-ic843wr9 242 15 diabetes diabetes NN cord-035067-ic843wr9 242 16 mellitus mellitus NN cord-035067-ic843wr9 242 17 , , , cord-035067-ic843wr9 242 18 cerebrovascular cerebrovascular JJ cord-035067-ic843wr9 242 19 disease disease NN cord-035067-ic843wr9 242 20 , , , cord-035067-ic843wr9 242 21 cardiovascular cardiovascular JJ cord-035067-ic843wr9 242 22 disease disease NN cord-035067-ic843wr9 242 23 , , , cord-035067-ic843wr9 242 24 lung lung NN cord-035067-ic843wr9 242 25 disease disease NN cord-035067-ic843wr9 242 26 , , , cord-035067-ic843wr9 242 27 kidney kidney NN cord-035067-ic843wr9 242 28 disease disease NN cord-035067-ic843wr9 242 29 , , , cord-035067-ic843wr9 242 30 liver liver NN cord-035067-ic843wr9 242 31 disease disease NN cord-035067-ic843wr9 242 32 , , , cord-035067-ic843wr9 242 33 and and CC cord-035067-ic843wr9 242 34 cancer cancer NN cord-035067-ic843wr9 242 35 , , , cord-035067-ic843wr9 242 36 among among IN cord-035067-ic843wr9 242 37 others other NNS cord-035067-ic843wr9 242 38 . . . cord-035067-ic843wr9 243 1 However however RB cord-035067-ic843wr9 243 2 , , , cord-035067-ic843wr9 243 3 only only RB cord-035067-ic843wr9 243 4 three three CD cord-035067-ic843wr9 243 5 articles article NNS cord-035067-ic843wr9 243 6 reported report VBD cord-035067-ic843wr9 243 7 a a DT cord-035067-ic843wr9 243 8 significant significant JJ cord-035067-ic843wr9 243 9 relation relation NN cord-035067-ic843wr9 243 10 between between IN cord-035067-ic843wr9 243 11 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 243 12 symptoms symptom NNS cord-035067-ic843wr9 243 13 and and CC cord-035067-ic843wr9 243 14 comorbidities comorbiditie NNS cord-035067-ic843wr9 243 15 , , , cord-035067-ic843wr9 243 16 and and CC cord-035067-ic843wr9 243 17 one one CD cord-035067-ic843wr9 243 18 of of IN cord-035067-ic843wr9 243 19 them -PRON- PRP cord-035067-ic843wr9 243 20 ins in VBZ cord-035067-ic843wr9 243 21 chronic chronic JJ cord-035067-ic843wr9 243 22 liver liver NN cord-035067-ic843wr9 243 23 disease disease NN cord-035067-ic843wr9 243 24 . . . cord-035067-ic843wr9 244 1 ( ( -LRB- cord-035067-ic843wr9 244 2 18 18 CD cord-035067-ic843wr9 244 3 , , , cord-035067-ic843wr9 244 4 21 21 CD cord-035067-ic843wr9 244 5 , , , cord-035067-ic843wr9 244 6 25 25 CD cord-035067-ic843wr9 244 7 ) ) -RRB- cord-035067-ic843wr9 245 1 On on IN cord-035067-ic843wr9 245 2 the the DT cord-035067-ic843wr9 245 3 other other JJ cord-035067-ic843wr9 245 4 hand hand NN cord-035067-ic843wr9 245 5 , , , cord-035067-ic843wr9 245 6 the the DT cord-035067-ic843wr9 245 7 relation relation NN cord-035067-ic843wr9 245 8 between between IN cord-035067-ic843wr9 245 9 COVID-19 COVID-19 NNP cord-035067-ic843wr9 245 10 and and CC cord-035067-ic843wr9 245 11 comorbidities comorbiditie NNS cord-035067-ic843wr9 245 12 also also RB cord-035067-ic843wr9 245 13 proved prove VBD cord-035067-ic843wr9 245 14 to to TO cord-035067-ic843wr9 245 15 be be VB cord-035067-ic843wr9 245 16 diverse diverse JJ cord-035067-ic843wr9 245 17 . . . cord-035067-ic843wr9 246 1 Very very RB cord-035067-ic843wr9 246 2 frequent frequent JJ cord-035067-ic843wr9 246 3 comorbidities comorbiditie NNS cord-035067-ic843wr9 246 4 in in IN cord-035067-ic843wr9 246 5 the the DT cord-035067-ic843wr9 246 6 population population NN cord-035067-ic843wr9 246 7 were be VBD cord-035067-ic843wr9 246 8 addressed address VBN cord-035067-ic843wr9 246 9 and and CC cord-035067-ic843wr9 246 10 may may MD cord-035067-ic843wr9 246 11 have have VB cord-035067-ic843wr9 246 12 important important JJ cord-035067-ic843wr9 246 13 significance significance NN cord-035067-ic843wr9 246 14 in in IN cord-035067-ic843wr9 246 15 SARS SARS NNP cord-035067-ic843wr9 246 16 - - HYPH cord-035067-ic843wr9 246 17 CoV-2 CoV-2 NNP cord-035067-ic843wr9 246 18 infection infection NN cord-035067-ic843wr9 246 19 and and CC cord-035067-ic843wr9 246 20 prognosis prognosis NN cord-035067-ic843wr9 246 21 . . . cord-035067-ic843wr9 247 1 The the DT cord-035067-ic843wr9 247 2 typical typical JJ cord-035067-ic843wr9 247 3 symptoms symptom NNS cord-035067-ic843wr9 247 4 most most RBS cord-035067-ic843wr9 247 5 often often RB cord-035067-ic843wr9 247 6 described describe VBN cord-035067-ic843wr9 247 7 are be VBP cord-035067-ic843wr9 247 8 common common JJ cord-035067-ic843wr9 247 9 in in IN cord-035067-ic843wr9 247 10 respiratory respiratory JJ cord-035067-ic843wr9 247 11 tract tract NN cord-035067-ic843wr9 247 12 infections infection NNS cord-035067-ic843wr9 247 13 , , , cord-035067-ic843wr9 247 14 such such JJ cord-035067-ic843wr9 247 15 as as IN cord-035067-ic843wr9 247 16 fever fever NN cord-035067-ic843wr9 247 17 ( ( -LRB- cord-035067-ic843wr9 247 18 76.7 76.7 CD cord-035067-ic843wr9 247 19 % % NN cord-035067-ic843wr9 247 20 to to IN cord-035067-ic843wr9 247 21 94.9 94.9 CD cord-035067-ic843wr9 247 22 % % NN cord-035067-ic843wr9 247 23 ) ) -RRB- cord-035067-ic843wr9 247 24 , , , cord-035067-ic843wr9 247 25 dry dry JJ cord-035067-ic843wr9 247 26 cough cough NN cord-035067-ic843wr9 247 27 ( ( -LRB- cord-035067-ic843wr9 247 28 38.6 38.6 CD cord-035067-ic843wr9 247 29 % % NN cord-035067-ic843wr9 247 30 to to IN cord-035067-ic843wr9 247 31 77.7 77.7 CD cord-035067-ic843wr9 247 32 % % NN cord-035067-ic843wr9 247 33 ) ) -RRB- cord-035067-ic843wr9 247 34 , , , cord-035067-ic843wr9 247 35 productive productive JJ cord-035067-ic843wr9 247 36 cough cough NN cord-035067-ic843wr9 247 37 ( ( -LRB- cord-035067-ic843wr9 247 38 14.2 14.2 CD cord-035067-ic843wr9 247 39 % % NN cord-035067-ic843wr9 247 40 to to IN cord-035067-ic843wr9 247 41 43.0 43.0 CD cord-035067-ic843wr9 247 42 % % NN cord-035067-ic843wr9 247 43 ) ) -RRB- cord-035067-ic843wr9 247 44 , , , cord-035067-ic843wr9 247 45 fatigue fatigue NN cord-035067-ic843wr9 247 46 ( ( -LRB- cord-035067-ic843wr9 247 47 16.6 16.6 CD cord-035067-ic843wr9 247 48 % % NN cord-035067-ic843wr9 247 49 to to IN cord-035067-ic843wr9 247 50 75.0 75.0 CD cord-035067-ic843wr9 247 51 % % NN cord-035067-ic843wr9 247 52 ) ) -RRB- cord-035067-ic843wr9 247 53 , , , cord-035067-ic843wr9 247 54 dyspnea dyspnea NN cord-035067-ic843wr9 247 55 ( ( -LRB- cord-035067-ic843wr9 247 56 3.3 3.3 CD cord-035067-ic843wr9 247 57 % % NN cord-035067-ic843wr9 247 58 to to IN cord-035067-ic843wr9 247 59 60.1 60.1 CD cord-035067-ic843wr9 247 60 % % NN cord-035067-ic843wr9 247 61 ) ) -RRB- cord-035067-ic843wr9 247 62 , , , cord-035067-ic843wr9 247 63 headache headache NN cord-035067-ic843wr9 247 64 ( ( -LRB- cord-035067-ic843wr9 247 65 8.0 8.0 CD cord-035067-ic843wr9 247 66 % % NN cord-035067-ic843wr9 247 67 to to IN cord-035067-ic843wr9 247 68 21.6 21.6 CD cord-035067-ic843wr9 247 69 % % NN cord-035067-ic843wr9 247 70 ) ) -RRB- cord-035067-ic843wr9 247 71 , , , cord-035067-ic843wr9 247 72 and and CC cord-035067-ic843wr9 247 73 sore sore JJ cord-035067-ic843wr9 247 74 throat throat NN cord-035067-ic843wr9 247 75 ( ( -LRB- cord-035067-ic843wr9 247 76 8.11 8.11 CD cord-035067-ic843wr9 247 77 % % NN cord-035067-ic843wr9 247 78 to to IN cord-035067-ic843wr9 247 79 17.0 17.0 CD cord-035067-ic843wr9 247 80 % % NN cord-035067-ic843wr9 247 81 ) ) -RRB- cord-035067-ic843wr9 247 82 . . . cord-035067-ic843wr9 248 1 ( ( -LRB- cord-035067-ic843wr9 248 2 8 8 CD cord-035067-ic843wr9 248 3 , , , cord-035067-ic843wr9 248 4 ( ( -LRB- cord-035067-ic843wr9 248 5 18 18 CD cord-035067-ic843wr9 248 6 ) ) -RRB- cord-035067-ic843wr9 248 7 ( ( -LRB- cord-035067-ic843wr9 248 8 19 19 CD cord-035067-ic843wr9 248 9 ) ) -RRB- cord-035067-ic843wr9 248 10 ( ( -LRB- cord-035067-ic843wr9 248 11 20 20 CD cord-035067-ic843wr9 248 12 ) ) -RRB- cord-035067-ic843wr9 248 13 ( ( -LRB- cord-035067-ic843wr9 248 14 21 21 CD cord-035067-ic843wr9 248 15 ) ) -RRB- cord-035067-ic843wr9 248 16 ( ( -LRB- cord-035067-ic843wr9 248 17 22 22 CD cord-035067-ic843wr9 248 18 ) ) -RRB- cord-035067-ic843wr9 248 19 ( ( -LRB- cord-035067-ic843wr9 248 20 23 23 CD cord-035067-ic843wr9 248 21 ) ) -RRB- cord-035067-ic843wr9 248 22 ( ( -LRB- cord-035067-ic843wr9 248 23 24 24 CD cord-035067-ic843wr9 248 24 ) ) -RRB- cord-035067-ic843wr9 248 25 ( ( -LRB- cord-035067-ic843wr9 248 26 25 25 CD cord-035067-ic843wr9 248 27 ) ) -RRB- cord-035067-ic843wr9 248 28 ( ( -LRB- cord-035067-ic843wr9 248 29 26 26 CD cord-035067-ic843wr9 248 30 ) ) -RRB- cord-035067-ic843wr9 248 31 ( ( -LRB- cord-035067-ic843wr9 248 32 27 27 CD cord-035067-ic843wr9 248 33 ) ) -RRB- cord-035067-ic843wr9 248 34 ( ( -LRB- cord-035067-ic843wr9 248 35 28 28 CD cord-035067-ic843wr9 248 36 ) ) -RRB- cord-035067-ic843wr9 248 37 ( ( -LRB- cord-035067-ic843wr9 248 38 29 29 CD cord-035067-ic843wr9 248 39 ) ) -RRB- cord-035067-ic843wr9 249 1 Other other JJ cord-035067-ic843wr9 249 2 symptoms symptom NNS cord-035067-ic843wr9 249 3 , , , cord-035067-ic843wr9 249 4 such such JJ cord-035067-ic843wr9 249 5 as as IN cord-035067-ic843wr9 249 6 anosmia anosmia NN cord-035067-ic843wr9 249 7 and and CC cord-035067-ic843wr9 249 8 ageusia ageusia NNP cord-035067-ic843wr9 249 9 , , , cord-035067-ic843wr9 249 10 are be VBP cord-035067-ic843wr9 249 11 closely closely RB cord-035067-ic843wr9 249 12 related relate VBN cord-035067-ic843wr9 249 13 to to IN cord-035067-ic843wr9 249 14 COVID-19 COVID-19 NNP cord-035067-ic843wr9 249 15 , , , cord-035067-ic843wr9 249 16 but but CC cord-035067-ic843wr9 249 17 only only RB cord-035067-ic843wr9 249 18 one one CD cord-035067-ic843wr9 249 19 study study NN cord-035067-ic843wr9 249 20 identified identify VBD cord-035067-ic843wr9 249 21 their -PRON- PRP$ cord-035067-ic843wr9 249 22 presence presence NN cord-035067-ic843wr9 249 23 ( ( -LRB- cord-035067-ic843wr9 249 24 10.1 10.1 CD cord-035067-ic843wr9 249 25 % % NN cord-035067-ic843wr9 249 26 and and CC cord-035067-ic843wr9 249 27 7.6 7.6 CD cord-035067-ic843wr9 249 28 % % NN cord-035067-ic843wr9 249 29 , , , cord-035067-ic843wr9 249 30 respectively respectively RB cord-035067-ic843wr9 249 31 ) ) -RRB- cord-035067-ic843wr9 249 32 . . . cord-035067-ic843wr9 250 1 This this DT cord-035067-ic843wr9 250 2 study study NN cord-035067-ic843wr9 250 3 found find VBD cord-035067-ic843wr9 250 4 a a DT cord-035067-ic843wr9 250 5 correlation correlation NN cord-035067-ic843wr9 250 6 between between IN cord-035067-ic843wr9 250 7 the the DT cord-035067-ic843wr9 250 8 presence presence NN cord-035067-ic843wr9 250 9 of of IN cord-035067-ic843wr9 250 10 fatigue fatigue NN cord-035067-ic843wr9 250 11 , , , cord-035067-ic843wr9 250 12 myalgia myalgia NN cord-035067-ic843wr9 250 13 , , , cord-035067-ic843wr9 250 14 dyspnea dyspnea NN cord-035067-ic843wr9 250 15 , , , cord-035067-ic843wr9 250 16 sore sore JJ cord-035067-ic843wr9 250 17 throat throat NN cord-035067-ic843wr9 250 18 , , , cord-035067-ic843wr9 250 19 anosmia anosmia NN cord-035067-ic843wr9 250 20 , , , cord-035067-ic843wr9 250 21 and and CC cord-035067-ic843wr9 250 22 ageusia ageusia NNP cord-035067-ic843wr9 250 23 with with IN cord-035067-ic843wr9 250 24 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 250 25 symptoms symptom NNS cord-035067-ic843wr9 250 26 . . . cord-035067-ic843wr9 251 1 ( ( -LRB- cord-035067-ic843wr9 251 2 22 22 CD cord-035067-ic843wr9 251 3 ) ) -RRB- cord-035067-ic843wr9 252 1 Two two CD cord-035067-ic843wr9 252 2 other other JJ cord-035067-ic843wr9 252 3 studies study NNS cord-035067-ic843wr9 252 4 also also RB cord-035067-ic843wr9 252 5 identified identify VBD cord-035067-ic843wr9 252 6 relation relation NN cord-035067-ic843wr9 252 7 between between IN cord-035067-ic843wr9 252 8 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 252 9 symptoms symptom NNS cord-035067-ic843wr9 252 10 and and CC cord-035067-ic843wr9 252 11 typical typical JJ cord-035067-ic843wr9 252 12 symptoms symptom NNS cord-035067-ic843wr9 252 13 ; ; : cord-035067-ic843wr9 252 14 one one CD cord-035067-ic843wr9 252 15 with with IN cord-035067-ic843wr9 252 16 fever fever NN cord-035067-ic843wr9 252 17 above above IN cord-035067-ic843wr9 252 18 38.5 38.5 CD cord-035067-ic843wr9 252 19 o o NN cord-035067-ic843wr9 252 20 C c NN cord-035067-ic843wr9 252 21 , , , cord-035067-ic843wr9 252 22 fatigue fatigue NN cord-035067-ic843wr9 252 23 , , , cord-035067-ic843wr9 252 24 dyspnea dyspnea NN cord-035067-ic843wr9 252 25 , , , cord-035067-ic843wr9 252 26 and and CC cord-035067-ic843wr9 252 27 headache headache NN cord-035067-ic843wr9 252 28 , , , cord-035067-ic843wr9 252 29 and and CC cord-035067-ic843wr9 252 30 the the DT cord-035067-ic843wr9 252 31 other other JJ cord-035067-ic843wr9 252 32 with with IN cord-035067-ic843wr9 252 33 fatigue fatigue NN cord-035067-ic843wr9 252 34 , , , cord-035067-ic843wr9 252 35 sore sore JJ cord-035067-ic843wr9 252 36 throat throat NN cord-035067-ic843wr9 252 37 , , , cord-035067-ic843wr9 252 38 and and CC cord-035067-ic843wr9 252 39 dizziness dizziness NN cord-035067-ic843wr9 252 40 . . . cord-035067-ic843wr9 253 1 ( ( -LRB- cord-035067-ic843wr9 253 2 18 18 CD cord-035067-ic843wr9 253 3 , , , cord-035067-ic843wr9 253 4 26 26 CD cord-035067-ic843wr9 253 5 ) ) -RRB- cord-035067-ic843wr9 254 1 Regarding regard VBG cord-035067-ic843wr9 254 2 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 254 3 symptoms symptom NNS cord-035067-ic843wr9 254 4 , , , cord-035067-ic843wr9 254 5 the the DT cord-035067-ic843wr9 254 6 prevalence prevalence NN cord-035067-ic843wr9 254 7 showed show VBD cord-035067-ic843wr9 254 8 great great JJ cord-035067-ic843wr9 254 9 variation variation NN cord-035067-ic843wr9 254 10 , , , cord-035067-ic843wr9 254 11 ranging range VBG cord-035067-ic843wr9 254 12 between between IN cord-035067-ic843wr9 254 13 6.8 6.8 CD cord-035067-ic843wr9 254 14 % % NN cord-035067-ic843wr9 254 15 and and CC cord-035067-ic843wr9 254 16 61.3 61.3 CD cord-035067-ic843wr9 254 17 % % NN cord-035067-ic843wr9 254 18 in in IN cord-035067-ic843wr9 254 19 these these DT cord-035067-ic843wr9 254 20 studies study NNS cord-035067-ic843wr9 254 21 . . . cord-035067-ic843wr9 255 1 This this DT cord-035067-ic843wr9 255 2 shows show VBZ cord-035067-ic843wr9 255 3 that that IN cord-035067-ic843wr9 255 4 there there EX cord-035067-ic843wr9 255 5 may may MD cord-035067-ic843wr9 255 6 be be VB cord-035067-ic843wr9 255 7 a a DT cord-035067-ic843wr9 255 8 regional regional JJ cord-035067-ic843wr9 255 9 trend trend NN cord-035067-ic843wr9 255 10 in in IN cord-035067-ic843wr9 255 11 them -PRON- PRP cord-035067-ic843wr9 255 12 , , , cord-035067-ic843wr9 255 13 and and CC cord-035067-ic843wr9 255 14 studies study NNS cord-035067-ic843wr9 255 15 with with IN cord-035067-ic843wr9 255 16 many many JJ cord-035067-ic843wr9 255 17 patients patient NNS cord-035067-ic843wr9 255 18 from from IN cord-035067-ic843wr9 255 19 several several JJ cord-035067-ic843wr9 255 20 countries country NNS cord-035067-ic843wr9 255 21 are be VBP cord-035067-ic843wr9 255 22 warranted warrant VBN cord-035067-ic843wr9 255 23 to to TO cord-035067-ic843wr9 255 24 improve improve VB cord-035067-ic843wr9 255 25 this this DT cord-035067-ic843wr9 255 26 relation relation NN cord-035067-ic843wr9 255 27 between between IN cord-035067-ic843wr9 255 28 GIT GIT NNP cord-035067-ic843wr9 255 29 and and CC cord-035067-ic843wr9 255 30 COVID-19 covid-19 NN cord-035067-ic843wr9 255 31 . . . cord-035067-ic843wr9 256 1 It -PRON- PRP cord-035067-ic843wr9 256 2 is be VBZ cord-035067-ic843wr9 256 3 important important JJ cord-035067-ic843wr9 256 4 to to TO cord-035067-ic843wr9 256 5 remember remember VB cord-035067-ic843wr9 256 6 that that IN cord-035067-ic843wr9 256 7 two two CD cord-035067-ic843wr9 256 8 meta meta JJ cord-035067-ic843wr9 256 9 - - HYPH cord-035067-ic843wr9 256 10 analyses analysis NNS cord-035067-ic843wr9 256 11 analysed analyse VBD cord-035067-ic843wr9 256 12 China China NNP cord-035067-ic843wr9 256 13 and and CC cord-035067-ic843wr9 256 14 other other JJ cord-035067-ic843wr9 256 15 countries country NNS cord-035067-ic843wr9 256 16 , , , cord-035067-ic843wr9 256 17 and and CC cord-035067-ic843wr9 256 18 showed show VBD cord-035067-ic843wr9 256 19 that that IN cord-035067-ic843wr9 256 20 the the DT cord-035067-ic843wr9 256 21 other other JJ cord-035067-ic843wr9 256 22 sites site NNS cord-035067-ic843wr9 256 23 presented present VBN cord-035067-ic843wr9 256 24 with with IN cord-035067-ic843wr9 256 25 higher high JJR cord-035067-ic843wr9 256 26 rates rate NNS cord-035067-ic843wr9 256 27 of of IN cord-035067-ic843wr9 256 28 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 256 29 symptoms symptom NNS cord-035067-ic843wr9 256 30 . . . cord-035067-ic843wr9 257 1 ( ( -LRB- cord-035067-ic843wr9 257 2 8 8 CD cord-035067-ic843wr9 257 3 , , , cord-035067-ic843wr9 257 4 27 27 CD cord-035067-ic843wr9 257 5 ) ) -RRB- cord-035067-ic843wr9 258 1 However however RB cord-035067-ic843wr9 258 2 , , , cord-035067-ic843wr9 258 3 there there EX cord-035067-ic843wr9 258 4 were be VBD cord-035067-ic843wr9 258 5 few few JJ cord-035067-ic843wr9 258 6 other other JJ cord-035067-ic843wr9 258 7 countries country NNS cord-035067-ic843wr9 258 8 , , , cord-035067-ic843wr9 258 9 and and CC cord-035067-ic843wr9 258 10 many many JJ cord-035067-ic843wr9 258 11 were be VBD cord-035067-ic843wr9 258 12 in in IN cord-035067-ic843wr9 258 13 Asia Asia NNP cord-035067-ic843wr9 258 14 . . . cord-035067-ic843wr9 259 1 Nevertheless nevertheless RB cord-035067-ic843wr9 259 2 , , , cord-035067-ic843wr9 259 3 this this DT cord-035067-ic843wr9 259 4 shows show VBZ cord-035067-ic843wr9 259 5 that that IN cord-035067-ic843wr9 259 6 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 259 7 symptoms symptom NNS cord-035067-ic843wr9 259 8 are be VBP cord-035067-ic843wr9 259 9 important important JJ cord-035067-ic843wr9 259 10 in in IN cord-035067-ic843wr9 259 11 this this DT cord-035067-ic843wr9 259 12 disease disease NN cord-035067-ic843wr9 259 13 , , , cord-035067-ic843wr9 259 14 may may MD cord-035067-ic843wr9 259 15 have have VB cord-035067-ic843wr9 259 16 a a DT cord-035067-ic843wr9 259 17 great great JJ cord-035067-ic843wr9 259 18 impact impact NN cord-035067-ic843wr9 259 19 in in IN cord-035067-ic843wr9 259 20 some some DT cord-035067-ic843wr9 259 21 countries country NNS cord-035067-ic843wr9 259 22 , , , cord-035067-ic843wr9 259 23 and and CC cord-035067-ic843wr9 259 24 should should MD cord-035067-ic843wr9 259 25 be be VB cord-035067-ic843wr9 259 26 evaluated evaluate VBN cord-035067-ic843wr9 259 27 based base VBN cord-035067-ic843wr9 259 28 on on IN cord-035067-ic843wr9 259 29 history history NN cord-035067-ic843wr9 259 30 of of IN cord-035067-ic843wr9 259 31 suspected suspect VBN cord-035067-ic843wr9 259 32 patients patient NNS cord-035067-ic843wr9 259 33 . . . cord-035067-ic843wr9 260 1 The the DT cord-035067-ic843wr9 260 2 most most RBS cord-035067-ic843wr9 260 3 often often RB cord-035067-ic843wr9 260 4 cited cite VBD cord-035067-ic843wr9 260 5 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 260 6 symptoms symptom NNS cord-035067-ic843wr9 260 7 were be VBD cord-035067-ic843wr9 260 8 diarrhea diarrhea JJ cord-035067-ic843wr9 260 9 ( ( -LRB- cord-035067-ic843wr9 260 10 8.14 8.14 CD cord-035067-ic843wr9 260 11 % % NN cord-035067-ic843wr9 260 12 to to IN cord-035067-ic843wr9 260 13 33.7 33.7 CD cord-035067-ic843wr9 260 14 % % NN cord-035067-ic843wr9 260 15 ) ) -RRB- cord-035067-ic843wr9 260 16 , , , cord-035067-ic843wr9 260 17 nausea nausea NN cord-035067-ic843wr9 260 18 / / SYM cord-035067-ic843wr9 260 19 vomiting vomiting NN cord-035067-ic843wr9 260 20 ( ( -LRB- cord-035067-ic843wr9 260 21 1.53 1.53 CD cord-035067-ic843wr9 260 22 % % NN cord-035067-ic843wr9 260 23 to to IN cord-035067-ic843wr9 260 24 26.4 26.4 CD cord-035067-ic843wr9 260 25 % % NN cord-035067-ic843wr9 260 26 ) ) -RRB- cord-035067-ic843wr9 260 27 , , , cord-035067-ic843wr9 260 28 anorexia anorexia NN cord-035067-ic843wr9 260 29 ( ( -LRB- cord-035067-ic843wr9 260 30 12.1 12.1 CD cord-035067-ic843wr9 260 31 % % NN cord-035067-ic843wr9 260 32 to to IN cord-035067-ic843wr9 260 33 40.0 40.0 CD cord-035067-ic843wr9 260 34 % % NN cord-035067-ic843wr9 260 35 ) ) -RRB- cord-035067-ic843wr9 260 36 , , , cord-035067-ic843wr9 260 37 and and CC cord-035067-ic843wr9 260 38 abdominal abdominal JJ cord-035067-ic843wr9 260 39 pain pain NN cord-035067-ic843wr9 260 40 ( ( -LRB- cord-035067-ic843wr9 260 41 0 0 CD cord-035067-ic843wr9 260 42 % % NN cord-035067-ic843wr9 260 43 to to TO cord-035067-ic843wr9 260 44 14.5 14.5 CD cord-035067-ic843wr9 260 45 % % NN cord-035067-ic843wr9 260 46 ) ) -RRB- cord-035067-ic843wr9 260 47 . . . cord-035067-ic843wr9 261 1 ( ( -LRB- cord-035067-ic843wr9 261 2 8 8 CD cord-035067-ic843wr9 261 3 , , , cord-035067-ic843wr9 261 4 ( ( -LRB- cord-035067-ic843wr9 261 5 18 18 CD cord-035067-ic843wr9 261 6 ) ) -RRB- cord-035067-ic843wr9 261 7 ( ( -LRB- cord-035067-ic843wr9 261 8 19 19 CD cord-035067-ic843wr9 261 9 ) ) -RRB- cord-035067-ic843wr9 261 10 ( ( -LRB- cord-035067-ic843wr9 261 11 20 20 CD cord-035067-ic843wr9 261 12 ) ) -RRB- cord-035067-ic843wr9 261 13 ( ( -LRB- cord-035067-ic843wr9 261 14 21 21 CD cord-035067-ic843wr9 261 15 ) ) -RRB- cord-035067-ic843wr9 261 16 ( ( -LRB- cord-035067-ic843wr9 261 17 22 22 CD cord-035067-ic843wr9 261 18 ) ) -RRB- cord-035067-ic843wr9 261 19 ( ( -LRB- cord-035067-ic843wr9 261 20 23 23 CD cord-035067-ic843wr9 261 21 ) ) -RRB- cord-035067-ic843wr9 261 22 ( ( -LRB- cord-035067-ic843wr9 261 23 24 24 CD cord-035067-ic843wr9 261 24 ) ) -RRB- cord-035067-ic843wr9 261 25 ( ( -LRB- cord-035067-ic843wr9 261 26 25 25 CD cord-035067-ic843wr9 261 27 ) ) -RRB- cord-035067-ic843wr9 261 28 ( ( -LRB- cord-035067-ic843wr9 261 29 26 26 CD cord-035067-ic843wr9 261 30 ) ) -RRB- cord-035067-ic843wr9 261 31 ( ( -LRB- cord-035067-ic843wr9 261 32 27 27 CD cord-035067-ic843wr9 261 33 ) ) -RRB- cord-035067-ic843wr9 261 34 ( ( -LRB- cord-035067-ic843wr9 261 35 28 28 CD cord-035067-ic843wr9 261 36 ) ) -RRB- cord-035067-ic843wr9 261 37 ( ( -LRB- cord-035067-ic843wr9 261 38 29 29 CD cord-035067-ic843wr9 261 39 ) ) -RRB- cord-035067-ic843wr9 262 1 Several several JJ cord-035067-ic843wr9 262 2 studies study NNS cord-035067-ic843wr9 262 3 point point VBP cord-035067-ic843wr9 262 4 out out RP cord-035067-ic843wr9 262 5 relations relation NNS cord-035067-ic843wr9 262 6 between between IN cord-035067-ic843wr9 262 7 laboratory laboratory NN cord-035067-ic843wr9 262 8 changes change NNS cord-035067-ic843wr9 262 9 and and CC cord-035067-ic843wr9 262 10 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 262 11 symptoms symptom NNS cord-035067-ic843wr9 262 12 or or CC cord-035067-ic843wr9 262 13 severity severity NN cord-035067-ic843wr9 262 14 of of IN cord-035067-ic843wr9 262 15 the the DT cord-035067-ic843wr9 262 16 disease disease NN cord-035067-ic843wr9 262 17 . . . cord-035067-ic843wr9 263 1 Liver liver NN cord-035067-ic843wr9 263 2 injury injury NN cord-035067-ic843wr9 263 3 ( ( -LRB- cord-035067-ic843wr9 263 4 elevation elevation NN cord-035067-ic843wr9 263 5 of of IN cord-035067-ic843wr9 263 6 AST AST NNP cord-035067-ic843wr9 263 7 , , , cord-035067-ic843wr9 263 8 ALT ALT NNP cord-035067-ic843wr9 263 9 , , , cord-035067-ic843wr9 263 10 and and CC cord-035067-ic843wr9 263 11 bilirubin bilirubin NN cord-035067-ic843wr9 263 12 ) ) -RRB- cord-035067-ic843wr9 263 13 was be VBD cord-035067-ic843wr9 263 14 the the DT cord-035067-ic843wr9 263 15 most most RBS cord-035067-ic843wr9 263 16 often often RB cord-035067-ic843wr9 263 17 evaluated evaluate VBN cord-035067-ic843wr9 263 18 , , , cord-035067-ic843wr9 263 19 but but CC cord-035067-ic843wr9 263 20 elevations elevation NNS cord-035067-ic843wr9 263 21 of of IN cord-035067-ic843wr9 263 22 C C NNP cord-035067-ic843wr9 263 23 - - HYPH cord-035067-ic843wr9 263 24 reactive reactive JJ cord-035067-ic843wr9 263 25 protein protein NN cord-035067-ic843wr9 263 26 , , , cord-035067-ic843wr9 263 27 procalcitonin procalcitonin NNS cord-035067-ic843wr9 263 28 , , , cord-035067-ic843wr9 263 29 lactate lactate NN cord-035067-ic843wr9 263 30 dehydrogenase dehydrogenase NN cord-035067-ic843wr9 263 31 , , , cord-035067-ic843wr9 263 32 D d NN cord-035067-ic843wr9 263 33 - - HYPH cord-035067-ic843wr9 263 34 dimer dimer NN cord-035067-ic843wr9 263 35 , , , cord-035067-ic843wr9 263 36 and and CC cord-035067-ic843wr9 263 37 prothrombin prothrombin NN cord-035067-ic843wr9 263 38 were be VBD cord-035067-ic843wr9 263 39 also also RB cord-035067-ic843wr9 263 40 verified verify VBN cord-035067-ic843wr9 263 41 , , , cord-035067-ic843wr9 263 42 as as RB cord-035067-ic843wr9 263 43 well well RB cord-035067-ic843wr9 263 44 as as IN cord-035067-ic843wr9 263 45 a a DT cord-035067-ic843wr9 263 46 decrease decrease NN cord-035067-ic843wr9 263 47 in in IN cord-035067-ic843wr9 263 48 serum serum NN cord-035067-ic843wr9 263 49 sodium sodium NN cord-035067-ic843wr9 263 50 levels level NNS cord-035067-ic843wr9 263 51 , , , cord-035067-ic843wr9 263 52 leukocytes leukocyte NNS cord-035067-ic843wr9 263 53 , , , cord-035067-ic843wr9 263 54 lymphocytes lymphocyte NNS cord-035067-ic843wr9 263 55 , , , cord-035067-ic843wr9 263 56 and and CC cord-035067-ic843wr9 263 57 monocytes monocyte NNS cord-035067-ic843wr9 263 58 . . . cord-035067-ic843wr9 264 1 ( ( -LRB- cord-035067-ic843wr9 264 2 8 8 CD cord-035067-ic843wr9 264 3 , , , cord-035067-ic843wr9 264 4 18 18 CD cord-035067-ic843wr9 264 5 , , , cord-035067-ic843wr9 264 6 20 20 CD cord-035067-ic843wr9 264 7 , , , cord-035067-ic843wr9 264 8 24 24 CD cord-035067-ic843wr9 264 9 , , , cord-035067-ic843wr9 264 10 25 25 CD cord-035067-ic843wr9 264 11 , , , cord-035067-ic843wr9 264 12 29 29 CD cord-035067-ic843wr9 264 13 ) ) -RRB- cord-035067-ic843wr9 265 1 Hence hence RB cord-035067-ic843wr9 265 2 , , , cord-035067-ic843wr9 265 3 it -PRON- PRP cord-035067-ic843wr9 265 4 is be VBZ cord-035067-ic843wr9 265 5 very very RB cord-035067-ic843wr9 265 6 important important JJ cord-035067-ic843wr9 265 7 to to TO cord-035067-ic843wr9 265 8 evaluate evaluate VB cord-035067-ic843wr9 265 9 these these DT cord-035067-ic843wr9 265 10 parameters parameter NNS cord-035067-ic843wr9 265 11 in in IN cord-035067-ic843wr9 265 12 patients patient NNS cord-035067-ic843wr9 265 13 hospitalized hospitalize VBN cord-035067-ic843wr9 265 14 with with IN cord-035067-ic843wr9 265 15 COVID-19 COVID-19 NNP cord-035067-ic843wr9 265 16 , , , cord-035067-ic843wr9 265 17 since since IN cord-035067-ic843wr9 265 18 they -PRON- PRP cord-035067-ic843wr9 265 19 may may MD cord-035067-ic843wr9 265 20 indicate indicate VB cord-035067-ic843wr9 265 21 a a DT cord-035067-ic843wr9 265 22 worse bad JJR cord-035067-ic843wr9 265 23 prognosis prognosis NN cord-035067-ic843wr9 265 24 of of IN cord-035067-ic843wr9 265 25 the the DT cord-035067-ic843wr9 265 26 disease disease NN cord-035067-ic843wr9 265 27 . . . cord-035067-ic843wr9 266 1 An an DT cord-035067-ic843wr9 266 2 important important JJ cord-035067-ic843wr9 266 3 factor factor NN cord-035067-ic843wr9 266 4 infrequently infrequently RB cord-035067-ic843wr9 266 5 evaluated evaluate VBD cord-035067-ic843wr9 266 6 among among IN cord-035067-ic843wr9 266 7 the the DT cord-035067-ic843wr9 266 8 studies study NNS cord-035067-ic843wr9 266 9 was be VBD cord-035067-ic843wr9 266 10 the the DT cord-035067-ic843wr9 266 11 presence presence NN cord-035067-ic843wr9 266 12 of of IN cord-035067-ic843wr9 266 13 viral viral JJ cord-035067-ic843wr9 266 14 RNA RNA NNP cord-035067-ic843wr9 266 15 in in IN cord-035067-ic843wr9 266 16 stool stool NN cord-035067-ic843wr9 266 17 samples sample NNS cord-035067-ic843wr9 266 18 from from IN cord-035067-ic843wr9 266 19 patients patient NNS cord-035067-ic843wr9 266 20 infected infect VBN cord-035067-ic843wr9 266 21 with with IN cord-035067-ic843wr9 266 22 SARS SARS NNP cord-035067-ic843wr9 266 23 - - HYPH cord-035067-ic843wr9 266 24 CoV-2 CoV-2 NNP cord-035067-ic843wr9 266 25 . . . cord-035067-ic843wr9 267 1 This this DT cord-035067-ic843wr9 267 2 data datum NNS cord-035067-ic843wr9 267 3 would would MD cord-035067-ic843wr9 267 4 help help VB cord-035067-ic843wr9 267 5 us -PRON- PRP cord-035067-ic843wr9 267 6 to to TO cord-035067-ic843wr9 267 7 understand understand VB cord-035067-ic843wr9 267 8 if if IN cord-035067-ic843wr9 267 9 there there EX cord-035067-ic843wr9 267 10 is be VBZ cord-035067-ic843wr9 267 11 a a DT cord-035067-ic843wr9 267 12 possibility possibility NN cord-035067-ic843wr9 267 13 of of IN cord-035067-ic843wr9 267 14 fecal fecal JJ cord-035067-ic843wr9 267 15 - - HYPH cord-035067-ic843wr9 267 16 oral oral JJ cord-035067-ic843wr9 267 17 transmission transmission NN cord-035067-ic843wr9 267 18 in in IN cord-035067-ic843wr9 267 19 this this DT cord-035067-ic843wr9 267 20 disease disease NN cord-035067-ic843wr9 267 21 . . . cord-035067-ic843wr9 268 1 Only only RB cord-035067-ic843wr9 268 2 four four CD cord-035067-ic843wr9 268 3 studies study NNS cord-035067-ic843wr9 268 4 performed perform VBD cord-035067-ic843wr9 268 5 this this DT cord-035067-ic843wr9 268 6 analysis analysis NN cord-035067-ic843wr9 268 7 , , , cord-035067-ic843wr9 268 8 in in IN cord-035067-ic843wr9 268 9 which which WDT cord-035067-ic843wr9 268 10 two two CD cord-035067-ic843wr9 268 11 were be VBD cord-035067-ic843wr9 268 12 meta meta NNP cord-035067-ic843wr9 268 13 - - HYPH cord-035067-ic843wr9 268 14 analyses analysis NNS cord-035067-ic843wr9 268 15 and and CC cord-035067-ic843wr9 268 16 two two CD cord-035067-ic843wr9 268 17 retrospective retrospective JJ cord-035067-ic843wr9 268 18 studies study NNS cord-035067-ic843wr9 268 19 . . . cord-035067-ic843wr9 269 1 This this DT cord-035067-ic843wr9 269 2 test test NN cord-035067-ic843wr9 269 3 was be VBD cord-035067-ic843wr9 269 4 positive positive JJ cord-035067-ic843wr9 269 5 in in IN cord-035067-ic843wr9 269 6 0 0 CD cord-035067-ic843wr9 269 7 % % NN cord-035067-ic843wr9 269 8 to to IN cord-035067-ic843wr9 269 9 48.1 48.1 CD cord-035067-ic843wr9 269 10 % % NN cord-035067-ic843wr9 269 11 of of IN cord-035067-ic843wr9 269 12 cases case NNS cord-035067-ic843wr9 269 13 , , , cord-035067-ic843wr9 269 14 with with IN cord-035067-ic843wr9 269 15 great great JJ cord-035067-ic843wr9 269 16 heterogeneity heterogeneity NN cord-035067-ic843wr9 269 17 in in IN cord-035067-ic843wr9 269 18 the the DT cord-035067-ic843wr9 269 19 results result NNS cord-035067-ic843wr9 269 20 , , , cord-035067-ic843wr9 269 21 but but CC cord-035067-ic843wr9 269 22 patients patient NNS cord-035067-ic843wr9 269 23 showing show VBG cord-035067-ic843wr9 269 24 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 269 25 symptoms symptom NNS cord-035067-ic843wr9 269 26 presented present VBD cord-035067-ic843wr9 269 27 more more RBR cord-035067-ic843wr9 269 28 frequently frequently RB cord-035067-ic843wr9 269 29 the the DT cord-035067-ic843wr9 269 30 presence presence NN cord-035067-ic843wr9 269 31 of of IN cord-035067-ic843wr9 269 32 virus virus NN cord-035067-ic843wr9 269 33 RNA RNA NNP cord-035067-ic843wr9 269 34 in in IN cord-035067-ic843wr9 269 35 feces fece NNS cord-035067-ic843wr9 269 36 . . . cord-035067-ic843wr9 270 1 ( ( -LRB- cord-035067-ic843wr9 270 2 8 8 CD cord-035067-ic843wr9 270 3 , , , cord-035067-ic843wr9 270 4 18 18 CD cord-035067-ic843wr9 270 5 , , , cord-035067-ic843wr9 270 6 19 19 CD cord-035067-ic843wr9 270 7 , , , cord-035067-ic843wr9 270 8 27 27 CD cord-035067-ic843wr9 270 9 ) ) -RRB- cord-035067-ic843wr9 270 10 Some some DT cord-035067-ic843wr9 270 11 also also RB cord-035067-ic843wr9 270 12 identified identify VBD cord-035067-ic843wr9 270 13 that that IN cord-035067-ic843wr9 270 14 this this DT cord-035067-ic843wr9 270 15 result result NN cord-035067-ic843wr9 270 16 remained remain VBD cord-035067-ic843wr9 270 17 positive positive JJ cord-035067-ic843wr9 270 18 even even RB cord-035067-ic843wr9 270 19 after after IN cord-035067-ic843wr9 270 20 the the DT cord-035067-ic843wr9 270 21 negativity negativity NN cord-035067-ic843wr9 270 22 of of IN cord-035067-ic843wr9 270 23 respiratory respiratory JJ cord-035067-ic843wr9 270 24 tract tract NN cord-035067-ic843wr9 270 25 samples sample NNS cord-035067-ic843wr9 270 26 . . . cord-035067-ic843wr9 271 1 In in IN cord-035067-ic843wr9 271 2 one one CD cord-035067-ic843wr9 271 3 of of IN cord-035067-ic843wr9 271 4 them -PRON- PRP cord-035067-ic843wr9 271 5 , , , cord-035067-ic843wr9 271 6 53.42 53.42 CD cord-035067-ic843wr9 271 7 % % NN cord-035067-ic843wr9 271 8 of of IN cord-035067-ic843wr9 271 9 feces fece NNS cord-035067-ic843wr9 271 10 samples sample NNS cord-035067-ic843wr9 271 11 were be VBD cord-035067-ic843wr9 271 12 positive positive JJ cord-035067-ic843wr9 271 13 for for IN cord-035067-ic843wr9 271 14 the the DT cord-035067-ic843wr9 271 15 virus virus NN cord-035067-ic843wr9 271 16 , , , cord-035067-ic843wr9 271 17 and and CC cord-035067-ic843wr9 271 18 23.29 23.29 CD cord-035067-ic843wr9 271 19 % % NN cord-035067-ic843wr9 271 20 were be VBD cord-035067-ic843wr9 271 21 still still RB cord-035067-ic843wr9 271 22 positive positive JJ cord-035067-ic843wr9 271 23 when when WRB cord-035067-ic843wr9 271 24 the the DT cord-035067-ic843wr9 271 25 respiratory respiratory JJ cord-035067-ic843wr9 271 26 tract tract NN cord-035067-ic843wr9 271 27 was be VBD cord-035067-ic843wr9 271 28 negative negative JJ cord-035067-ic843wr9 271 29 . . . cord-035067-ic843wr9 272 1 ( ( -LRB- cord-035067-ic843wr9 272 2 30 30 CD cord-035067-ic843wr9 272 3 ) ) -RRB- cord-035067-ic843wr9 273 1 In in IN cord-035067-ic843wr9 273 2 another another DT cord-035067-ic843wr9 273 3 , , , cord-035067-ic843wr9 273 4 70.3 70.3 CD cord-035067-ic843wr9 273 5 % % NN cord-035067-ic843wr9 273 6 of of IN cord-035067-ic843wr9 273 7 patients patient NNS cord-035067-ic843wr9 273 8 who who WP cord-035067-ic843wr9 273 9 had have VBD cord-035067-ic843wr9 273 10 feces fece NNS cord-035067-ic843wr9 273 11 positive positive JJ cord-035067-ic843wr9 273 12 for for IN cord-035067-ic843wr9 273 13 the the DT cord-035067-ic843wr9 273 14 virus virus NN cord-035067-ic843wr9 273 15 ( ( -LRB- cord-035067-ic843wr9 273 16 48.1 48.1 CD cord-035067-ic843wr9 273 17 % % NN cord-035067-ic843wr9 273 18 ) ) -RRB- cord-035067-ic843wr9 273 19 also also RB cord-035067-ic843wr9 273 20 remained remain VBD cord-035067-ic843wr9 273 21 positive positive JJ cord-035067-ic843wr9 273 22 after after IN cord-035067-ic843wr9 273 23 respiratory respiratory JJ cord-035067-ic843wr9 273 24 clearance clearance NN cord-035067-ic843wr9 273 25 . . . cord-035067-ic843wr9 274 1 ( ( -LRB- cord-035067-ic843wr9 274 2 27 27 CD cord-035067-ic843wr9 274 3 ) ) -RRB- cord-035067-ic843wr9 275 1 However however RB cord-035067-ic843wr9 275 2 , , , cord-035067-ic843wr9 275 3 studies study NNS cord-035067-ic843wr9 275 4 did do VBD cord-035067-ic843wr9 275 5 not not RB cord-035067-ic843wr9 275 6 evaluate evaluate VB cord-035067-ic843wr9 275 7 whether whether IN cord-035067-ic843wr9 275 8 the the DT cord-035067-ic843wr9 275 9 RNA RNA NNP cord-035067-ic843wr9 275 10 present present NN cord-035067-ic843wr9 275 11 in in IN cord-035067-ic843wr9 275 12 feces fece NNS cord-035067-ic843wr9 275 13 represents represent VBZ cord-035067-ic843wr9 275 14 infecting infect VBG cord-035067-ic843wr9 275 15 virus virus NN cord-035067-ic843wr9 275 16 or or CC cord-035067-ic843wr9 275 17 only only JJ cord-035067-ic843wr9 275 18 viral viral JJ cord-035067-ic843wr9 275 19 residues residue NNS cord-035067-ic843wr9 275 20 , , , cord-035067-ic843wr9 275 21 with with IN cord-035067-ic843wr9 275 22 no no DT cord-035067-ic843wr9 275 23 capacity capacity NN cord-035067-ic843wr9 275 24 to to TO cord-035067-ic843wr9 275 25 infect infect VB cord-035067-ic843wr9 275 26 . . . cord-035067-ic843wr9 276 1 These these DT cord-035067-ic843wr9 276 2 data datum NNS cord-035067-ic843wr9 276 3 lead lead VBP cord-035067-ic843wr9 276 4 us -PRON- PRP cord-035067-ic843wr9 276 5 to to TO cord-035067-ic843wr9 276 6 doubt doubt VB cord-035067-ic843wr9 276 7 whether whether IN cord-035067-ic843wr9 276 8 the the DT cord-035067-ic843wr9 276 9 PCR PCR NNP cord-035067-ic843wr9 276 10 test test NN cord-035067-ic843wr9 276 11 in in IN cord-035067-ic843wr9 276 12 feces fece NNS cord-035067-ic843wr9 276 13 of of IN cord-035067-ic843wr9 276 14 patients patient NNS cord-035067-ic843wr9 276 15 with with IN cord-035067-ic843wr9 276 16 COVID-19 COVID-19 NNP cord-035067-ic843wr9 276 17 should should MD cord-035067-ic843wr9 276 18 be be VB cord-035067-ic843wr9 276 19 done do VBN cord-035067-ic843wr9 276 20 routinely routinely RB cord-035067-ic843wr9 276 21 or or CC cord-035067-ic843wr9 276 22 not not RB cord-035067-ic843wr9 276 23 . . . cord-035067-ic843wr9 277 1 Therefore therefore RB cord-035067-ic843wr9 277 2 , , , cord-035067-ic843wr9 277 3 further further JJ cord-035067-ic843wr9 277 4 studies study NNS cord-035067-ic843wr9 277 5 should should MD cord-035067-ic843wr9 277 6 be be VB cord-035067-ic843wr9 277 7 concerned concern VBN cord-035067-ic843wr9 277 8 and and CC cord-035067-ic843wr9 277 9 evaluate evaluate VB cord-035067-ic843wr9 277 10 this this DT cord-035067-ic843wr9 277 11 issue issue NN cord-035067-ic843wr9 277 12 , , , cord-035067-ic843wr9 277 13 as as IN cord-035067-ic843wr9 277 14 possible possible JJ cord-035067-ic843wr9 277 15 fecal fecal JJ cord-035067-ic843wr9 277 16 - - HYPH cord-035067-ic843wr9 277 17 oral oral JJ cord-035067-ic843wr9 277 18 transmission transmission NN cord-035067-ic843wr9 277 19 can can MD cord-035067-ic843wr9 277 20 have have VB cord-035067-ic843wr9 277 21 a a DT cord-035067-ic843wr9 277 22 major major JJ cord-035067-ic843wr9 277 23 impact impact NN cord-035067-ic843wr9 277 24 in in IN cord-035067-ic843wr9 277 25 developing develop VBG cord-035067-ic843wr9 277 26 countries country NNS cord-035067-ic843wr9 277 27 that that WDT cord-035067-ic843wr9 277 28 lack lack VBP cord-035067-ic843wr9 277 29 basic basic JJ cord-035067-ic843wr9 277 30 sanitation sanitation NN cord-035067-ic843wr9 277 31 in in IN cord-035067-ic843wr9 277 32 many many JJ cord-035067-ic843wr9 277 33 places place NNS cord-035067-ic843wr9 277 34 . . . cord-035067-ic843wr9 278 1 Finally finally RB cord-035067-ic843wr9 278 2 , , , cord-035067-ic843wr9 278 3 the the DT cord-035067-ic843wr9 278 4 need need NN cord-035067-ic843wr9 278 5 for for IN cord-035067-ic843wr9 278 6 ICU ICU NNP cord-035067-ic843wr9 278 7 admission admission NN cord-035067-ic843wr9 278 8 ranged range VBD cord-035067-ic843wr9 278 9 from from IN cord-035067-ic843wr9 278 10 2.08 2.08 CD cord-035067-ic843wr9 278 11 % % NN cord-035067-ic843wr9 278 12 to to IN cord-035067-ic843wr9 278 13 31.0 31.0 CD cord-035067-ic843wr9 278 14 % % NN cord-035067-ic843wr9 278 15 , , , cord-035067-ic843wr9 278 16 and and CC cord-035067-ic843wr9 278 17 cases case NNS cord-035067-ic843wr9 278 18 that that WDT cord-035067-ic843wr9 278 19 had have VBD cord-035067-ic843wr9 278 20 evolved evolve VBN cord-035067-ic843wr9 278 21 to to IN cord-035067-ic843wr9 278 22 death death NN cord-035067-ic843wr9 278 23 from from IN cord-035067-ic843wr9 278 24 0 0 CD cord-035067-ic843wr9 278 25 % % NN cord-035067-ic843wr9 278 26 to to TO cord-035067-ic843wr9 278 27 17.65 17.65 CD cord-035067-ic843wr9 278 28 % % NN cord-035067-ic843wr9 278 29 . . . cord-035067-ic843wr9 279 1 Several several JJ cord-035067-ic843wr9 279 2 studies study NNS cord-035067-ic843wr9 279 3 have have VBP cord-035067-ic843wr9 279 4 commented comment VBN cord-035067-ic843wr9 279 5 on on IN cord-035067-ic843wr9 279 6 this this DT cord-035067-ic843wr9 279 7 , , , cord-035067-ic843wr9 279 8 but but CC cord-035067-ic843wr9 279 9 only only RB cord-035067-ic843wr9 279 10 two two CD cord-035067-ic843wr9 279 11 presented present VBN cord-035067-ic843wr9 279 12 with with IN cord-035067-ic843wr9 279 13 a a DT cord-035067-ic843wr9 279 14 significant significant JJ cord-035067-ic843wr9 279 15 difference difference NN cord-035067-ic843wr9 279 16 between between IN cord-035067-ic843wr9 279 17 the the DT cord-035067-ic843wr9 279 18 presence presence NN cord-035067-ic843wr9 279 19 of of IN cord-035067-ic843wr9 279 20 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 279 21 symptoms symptom NNS cord-035067-ic843wr9 279 22 and and CC cord-035067-ic843wr9 279 23 the the DT cord-035067-ic843wr9 279 24 need need NN cord-035067-ic843wr9 279 25 for for IN cord-035067-ic843wr9 279 26 ICU ICU NNP cord-035067-ic843wr9 279 27 , , , cord-035067-ic843wr9 279 28 or or CC cord-035067-ic843wr9 279 29 death death NN cord-035067-ic843wr9 279 30 . . . cord-035067-ic843wr9 280 1 ( ( -LRB- cord-035067-ic843wr9 280 2 8 8 CD cord-035067-ic843wr9 280 3 , , , cord-035067-ic843wr9 280 4 21 21 CD cord-035067-ic843wr9 280 5 ) ) -RRB- cord-035067-ic843wr9 281 1 Thus thus RB cord-035067-ic843wr9 281 2 , , , cord-035067-ic843wr9 281 3 the the DT cord-035067-ic843wr9 281 4 investigation investigation NN cord-035067-ic843wr9 281 5 of of IN cord-035067-ic843wr9 281 6 these these DT cord-035067-ic843wr9 281 7 patients patient NNS cord-035067-ic843wr9 281 8 with with IN cord-035067-ic843wr9 281 9 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 281 10 symptoms symptom NNS cord-035067-ic843wr9 281 11 since since IN cord-035067-ic843wr9 281 12 the the DT cord-035067-ic843wr9 281 13 onset onset NN cord-035067-ic843wr9 281 14 of of IN cord-035067-ic843wr9 281 15 the the DT cord-035067-ic843wr9 281 16 infectious infectious JJ cord-035067-ic843wr9 281 17 condition condition NN cord-035067-ic843wr9 281 18 becomes become VBZ cord-035067-ic843wr9 281 19 very very RB cord-035067-ic843wr9 281 20 important important JJ cord-035067-ic843wr9 281 21 , , , cord-035067-ic843wr9 281 22 considering consider VBG cord-035067-ic843wr9 281 23 many many JJ cord-035067-ic843wr9 281 24 of of IN cord-035067-ic843wr9 281 25 them -PRON- PRP cord-035067-ic843wr9 281 26 , , , cord-035067-ic843wr9 281 27 more more JJR cord-035067-ic843wr9 281 28 than than IN cord-035067-ic843wr9 281 29 those those DT cord-035067-ic843wr9 281 30 without without IN cord-035067-ic843wr9 281 31 these these DT cord-035067-ic843wr9 281 32 symptoms symptom NNS cord-035067-ic843wr9 281 33 , , , cord-035067-ic843wr9 281 34 may may MD cord-035067-ic843wr9 281 35 develop develop VB cord-035067-ic843wr9 281 36 a a DT cord-035067-ic843wr9 281 37 more more RBR cord-035067-ic843wr9 281 38 serious serious JJ cord-035067-ic843wr9 281 39 disease disease NN cord-035067-ic843wr9 281 40 and and CC cord-035067-ic843wr9 281 41 need need VB cord-035067-ic843wr9 281 42 ICU ICU NNP cord-035067-ic843wr9 281 43 , , , cord-035067-ic843wr9 281 44 or or CC cord-035067-ic843wr9 281 45 even even RB cord-035067-ic843wr9 281 46 progress progress VB cord-035067-ic843wr9 281 47 to to IN cord-035067-ic843wr9 281 48 death death NN cord-035067-ic843wr9 281 49 . . . cord-035067-ic843wr9 282 1 The the DT cord-035067-ic843wr9 282 2 articles article NNS cord-035067-ic843wr9 282 3 in in IN cord-035067-ic843wr9 282 4 this this DT cord-035067-ic843wr9 282 5 review review NN cord-035067-ic843wr9 282 6 have have VBP cord-035067-ic843wr9 282 7 several several JJ cord-035067-ic843wr9 282 8 limitations limitation NNS cord-035067-ic843wr9 282 9 . . . cord-035067-ic843wr9 283 1 In in IN cord-035067-ic843wr9 283 2 general general JJ cord-035067-ic843wr9 283 3 , , , cord-035067-ic843wr9 283 4 the the DT cord-035067-ic843wr9 283 5 evaluation evaluation NN cord-035067-ic843wr9 283 6 of of IN cord-035067-ic843wr9 283 7 the the DT cord-035067-ic843wr9 283 8 symptoms symptom NNS cord-035067-ic843wr9 283 9 was be VBD cord-035067-ic843wr9 283 10 done do VBN cord-035067-ic843wr9 283 11 differently differently RB cord-035067-ic843wr9 283 12 among among IN cord-035067-ic843wr9 283 13 them -PRON- PRP cord-035067-ic843wr9 283 14 , , , cord-035067-ic843wr9 283 15 there there EX cord-035067-ic843wr9 283 16 may may MD cord-035067-ic843wr9 283 17 be be VB cord-035067-ic843wr9 283 18 underreporting underreporte VBG cord-035067-ic843wr9 283 19 of of IN cord-035067-ic843wr9 283 20 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 283 21 symptoms symptom NNS cord-035067-ic843wr9 283 22 , , , cord-035067-ic843wr9 283 23 and and CC cord-035067-ic843wr9 283 24 few few JJ cord-035067-ic843wr9 283 25 were be VBD cord-035067-ic843wr9 283 26 carried carry VBN cord-035067-ic843wr9 283 27 out out RP cord-035067-ic843wr9 283 28 with with IN cord-035067-ic843wr9 283 29 patients patient NNS cord-035067-ic843wr9 283 30 outside outside IN cord-035067-ic843wr9 283 31 China China NNP cord-035067-ic843wr9 283 32 . . . cord-035067-ic843wr9 284 1 Additionally additionally RB cord-035067-ic843wr9 284 2 , , , cord-035067-ic843wr9 284 3 the the DT cord-035067-ic843wr9 284 4 design design NN cord-035067-ic843wr9 284 5 was be VBD cord-035067-ic843wr9 284 6 retrospective retrospective JJ cord-035067-ic843wr9 284 7 and and CC cord-035067-ic843wr9 284 8 had have VBD cord-035067-ic843wr9 284 9 small small JJ cord-035067-ic843wr9 284 10 samples sample NNS cord-035067-ic843wr9 284 11 , , , cord-035067-ic843wr9 284 12 many many JJ cord-035067-ic843wr9 284 13 did do VBD cord-035067-ic843wr9 284 14 not not RB cord-035067-ic843wr9 284 15 evaluate evaluate VB cord-035067-ic843wr9 284 16 the the DT cord-035067-ic843wr9 284 17 presence presence NN cord-035067-ic843wr9 284 18 of of IN cord-035067-ic843wr9 284 19 viral viral JJ cord-035067-ic843wr9 284 20 RNA RNA NNP cord-035067-ic843wr9 284 21 in in IN cord-035067-ic843wr9 284 22 feces fece NNS cord-035067-ic843wr9 284 23 , , , cord-035067-ic843wr9 284 24 did do VBD cord-035067-ic843wr9 284 25 not not RB cord-035067-ic843wr9 284 26 include include VB cord-035067-ic843wr9 284 27 asymptomatic asymptomatic JJ cord-035067-ic843wr9 284 28 patients patient NNS cord-035067-ic843wr9 284 29 , , , cord-035067-ic843wr9 284 30 the the DT cord-035067-ic843wr9 284 31 data datum NNS cord-035067-ic843wr9 284 32 were be VBD cord-035067-ic843wr9 284 33 hospital hospital NN cord-035067-ic843wr9 284 34 data datum NNS cord-035067-ic843wr9 284 35 , , , cord-035067-ic843wr9 284 36 and and CC cord-035067-ic843wr9 284 37 the the DT cord-035067-ic843wr9 284 38 follow follow NN cord-035067-ic843wr9 284 39 - - HYPH cord-035067-ic843wr9 284 40 up up NN cord-035067-ic843wr9 284 41 of of IN cord-035067-ic843wr9 284 42 patients patient NNS cord-035067-ic843wr9 284 43 was be VBD cord-035067-ic843wr9 284 44 short short JJ cord-035067-ic843wr9 284 45 . . . cord-035067-ic843wr9 285 1 Moreover moreover RB cord-035067-ic843wr9 285 2 , , , cord-035067-ic843wr9 285 3 because because IN cord-035067-ic843wr9 285 4 this this DT cord-035067-ic843wr9 285 5 review review NN cord-035067-ic843wr9 285 6 includes include VBZ cord-035067-ic843wr9 285 7 different different JJ cord-035067-ic843wr9 285 8 study study NN cord-035067-ic843wr9 285 9 designs design NNS cord-035067-ic843wr9 285 10 , , , cord-035067-ic843wr9 285 11 einstein einstein NNP cord-035067-ic843wr9 285 12 ( ( -LRB- cord-035067-ic843wr9 285 13 São São NNP cord-035067-ic843wr9 285 14 Paulo Paulo NNP cord-035067-ic843wr9 285 15 ) ) -RRB- cord-035067-ic843wr9 285 16 . . . cord-035067-ic843wr9 286 1 2020;18:1 2020;18:1 CD cord-035067-ic843wr9 286 2 - - SYM cord-035067-ic843wr9 286 3 14 14 CD cord-035067-ic843wr9 286 4 there there EX cord-035067-ic843wr9 286 5 is be VBZ cord-035067-ic843wr9 286 6 a a DT cord-035067-ic843wr9 286 7 risk risk NN cord-035067-ic843wr9 286 8 that that IN cord-035067-ic843wr9 286 9 the the DT cord-035067-ic843wr9 286 10 meta meta NNP cord-035067-ic843wr9 286 11 - - HYPH cord-035067-ic843wr9 286 12 analyses analysis NNS cord-035067-ic843wr9 286 13 and and CC cord-035067-ic843wr9 286 14 systematic systematic JJ cord-035067-ic843wr9 286 15 reviews review NNS cord-035067-ic843wr9 286 16 also also RB cord-035067-ic843wr9 286 17 contain contain VBP cord-035067-ic843wr9 286 18 some some DT cord-035067-ic843wr9 286 19 retrospective retrospective JJ cord-035067-ic843wr9 286 20 article article NN cord-035067-ic843wr9 286 21 and and CC cord-035067-ic843wr9 286 22 may may MD cord-035067-ic843wr9 286 23 have have VB cord-035067-ic843wr9 286 24 duplicate duplicate JJ cord-035067-ic843wr9 286 25 results result NNS cord-035067-ic843wr9 286 26 . . . cord-035067-ic843wr9 287 1 The the DT cord-035067-ic843wr9 287 2 various various JJ cord-035067-ic843wr9 287 3 study study NN cord-035067-ic843wr9 287 4 designs design NNS cord-035067-ic843wr9 287 5 , , , cord-035067-ic843wr9 287 6 per per FW cord-035067-ic843wr9 287 7 se se FW cord-035067-ic843wr9 287 8 , , , cord-035067-ic843wr9 287 9 are be VBP cord-035067-ic843wr9 287 10 also also RB cord-035067-ic843wr9 287 11 a a DT cord-035067-ic843wr9 287 12 limitation limitation NN cord-035067-ic843wr9 287 13 of of IN cord-035067-ic843wr9 287 14 this this DT cord-035067-ic843wr9 287 15 review review NN cord-035067-ic843wr9 287 16 , , , cord-035067-ic843wr9 287 17 since since IN cord-035067-ic843wr9 287 18 the the DT cord-035067-ic843wr9 287 19 ideal ideal NN cord-035067-ic843wr9 287 20 would would MD cord-035067-ic843wr9 287 21 be be VB cord-035067-ic843wr9 287 22 to to TO cord-035067-ic843wr9 287 23 use use VB cord-035067-ic843wr9 287 24 the the DT cord-035067-ic843wr9 287 25 same same JJ cord-035067-ic843wr9 287 26 model model NN cord-035067-ic843wr9 287 27 . . . cord-035067-ic843wr9 288 1 The the DT cord-035067-ic843wr9 288 2 high high JJ cord-035067-ic843wr9 288 3 rates rate NNS cord-035067-ic843wr9 288 4 of of IN cord-035067-ic843wr9 288 5 SARS SARS NNP cord-035067-ic843wr9 288 6 - - HYPH cord-035067-ic843wr9 288 7 CoV-2 CoV-2 NNP cord-035067-ic843wr9 288 8 infection infection NN cord-035067-ic843wr9 288 9 worldwide worldwide RB cord-035067-ic843wr9 288 10 have have VBP cord-035067-ic843wr9 288 11 caused cause VBN cord-035067-ic843wr9 288 12 the the DT cord-035067-ic843wr9 288 13 World World NNP cord-035067-ic843wr9 288 14 Health Health NNP cord-035067-ic843wr9 288 15 Organization Organization NNP cord-035067-ic843wr9 288 16 to to TO cord-035067-ic843wr9 288 17 declare declare VB cord-035067-ic843wr9 288 18 a a DT cord-035067-ic843wr9 288 19 pandemic pandemic NN cord-035067-ic843wr9 288 20 in in IN cord-035067-ic843wr9 288 21 2020 2020 CD cord-035067-ic843wr9 288 22 . . . cord-035067-ic843wr9 289 1 Therefore therefore RB cord-035067-ic843wr9 289 2 , , , cord-035067-ic843wr9 289 3 information information NN cord-035067-ic843wr9 289 4 about about IN cord-035067-ic843wr9 289 5 this this DT cord-035067-ic843wr9 289 6 new new JJ cord-035067-ic843wr9 289 7 disease disease NN cord-035067-ic843wr9 289 8 is be VBZ cord-035067-ic843wr9 289 9 of of IN cord-035067-ic843wr9 289 10 extreme extreme JJ cord-035067-ic843wr9 289 11 importance importance NN cord-035067-ic843wr9 289 12 , , , cord-035067-ic843wr9 289 13 both both CC cord-035067-ic843wr9 289 14 in in IN cord-035067-ic843wr9 289 15 terms term NNS cord-035067-ic843wr9 289 16 of of IN cord-035067-ic843wr9 289 17 pathophysiology pathophysiology NN cord-035067-ic843wr9 289 18 and and CC cord-035067-ic843wr9 289 19 prevalence prevalence NN cord-035067-ic843wr9 289 20 , , , cord-035067-ic843wr9 289 21 severity severity NN cord-035067-ic843wr9 289 22 , , , cord-035067-ic843wr9 289 23 risk risk NN cord-035067-ic843wr9 289 24 factors factor NNS cord-035067-ic843wr9 289 25 , , , cord-035067-ic843wr9 289 26 diagnosis diagnosis NN cord-035067-ic843wr9 289 27 , , , cord-035067-ic843wr9 289 28 and and CC cord-035067-ic843wr9 289 29 treatment treatment NN cord-035067-ic843wr9 289 30 . . . cord-035067-ic843wr9 290 1 With with IN cord-035067-ic843wr9 290 2 this this DT cord-035067-ic843wr9 290 3 effort effort NN cord-035067-ic843wr9 290 4 , , , cord-035067-ic843wr9 290 5 we -PRON- PRP cord-035067-ic843wr9 290 6 realize realize VBP cord-035067-ic843wr9 290 7 that that IN cord-035067-ic843wr9 290 8 the the DT cord-035067-ic843wr9 290 9 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 290 10 tract tract NN cord-035067-ic843wr9 290 11 can can MD cord-035067-ic843wr9 290 12 be be VB cord-035067-ic843wr9 290 13 greatly greatly RB cord-035067-ic843wr9 290 14 influenced influence VBN cord-035067-ic843wr9 290 15 by by IN cord-035067-ic843wr9 290 16 the the DT cord-035067-ic843wr9 290 17 disease disease NN cord-035067-ic843wr9 290 18 , , , cord-035067-ic843wr9 290 19 causing cause VBG cord-035067-ic843wr9 290 20 specific specific JJ cord-035067-ic843wr9 290 21 symptoms symptom NNS cord-035067-ic843wr9 290 22 ( ( -LRB- cord-035067-ic843wr9 290 23 diarrhea diarrhea NN cord-035067-ic843wr9 290 24 , , , cord-035067-ic843wr9 290 25 abdominal abdominal JJ cord-035067-ic843wr9 290 26 pain pain NN cord-035067-ic843wr9 290 27 , , , cord-035067-ic843wr9 290 28 nausea nausea NN cord-035067-ic843wr9 290 29 , , , cord-035067-ic843wr9 290 30 and and CC cord-035067-ic843wr9 290 31 vomiting vomit VBG cord-035067-ic843wr9 290 32 ) ) -RRB- cord-035067-ic843wr9 290 33 and and CC cord-035067-ic843wr9 290 34 laboratory laboratory NN cord-035067-ic843wr9 290 35 changes change NNS cord-035067-ic843wr9 290 36 ( ( -LRB- cord-035067-ic843wr9 290 37 mainly mainly RB cord-035067-ic843wr9 290 38 of of IN cord-035067-ic843wr9 290 39 hepatic hepatic JJ cord-035067-ic843wr9 290 40 enzymes enzyme NNS cord-035067-ic843wr9 290 41 ) ) -RRB- cord-035067-ic843wr9 290 42 . . . cord-035067-ic843wr9 291 1 Health health NN cord-035067-ic843wr9 291 2 professionals professional NNS cord-035067-ic843wr9 291 3 should should MD cord-035067-ic843wr9 291 4 pay pay VB cord-035067-ic843wr9 291 5 attention attention NN cord-035067-ic843wr9 291 6 to to IN cord-035067-ic843wr9 291 7 this this DT cord-035067-ic843wr9 291 8 , , , cord-035067-ic843wr9 291 9 keeping keep VBG cord-035067-ic843wr9 291 10 alert alert JJ cord-035067-ic843wr9 291 11 to to IN cord-035067-ic843wr9 291 12 the the DT cord-035067-ic843wr9 291 13 modifications modification NNS cord-035067-ic843wr9 291 14 that that WDT cord-035067-ic843wr9 291 15 can can MD cord-035067-ic843wr9 291 16 help help VB cord-035067-ic843wr9 291 17 in in IN cord-035067-ic843wr9 291 18 the the DT cord-035067-ic843wr9 291 19 diagnosis diagnosis NN cord-035067-ic843wr9 291 20 , , , cord-035067-ic843wr9 291 21 and and CC cord-035067-ic843wr9 291 22 initiate initiate VB cord-035067-ic843wr9 291 23 early early JJ cord-035067-ic843wr9 291 24 treatment treatment NN cord-035067-ic843wr9 291 25 in in IN cord-035067-ic843wr9 291 26 order order NN cord-035067-ic843wr9 291 27 to to TO cord-035067-ic843wr9 291 28 avoid avoid VB cord-035067-ic843wr9 291 29 bad bad JJ cord-035067-ic843wr9 291 30 prognosis prognosis NN cord-035067-ic843wr9 291 31 . . . cord-035067-ic843wr9 292 1 However however RB cord-035067-ic843wr9 292 2 , , , cord-035067-ic843wr9 292 3 the the DT cord-035067-ic843wr9 292 4 results result NNS cord-035067-ic843wr9 292 5 of of IN cord-035067-ic843wr9 292 6 prevalence prevalence NN cord-035067-ic843wr9 292 7 of of IN cord-035067-ic843wr9 292 8 the the DT cord-035067-ic843wr9 292 9 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 292 10 symptoms symptom NNS cord-035067-ic843wr9 292 11 were be VBD cord-035067-ic843wr9 292 12 very very RB cord-035067-ic843wr9 292 13 different different JJ cord-035067-ic843wr9 292 14 , , , cord-035067-ic843wr9 292 15 presenting present VBG cord-035067-ic843wr9 292 16 a a DT cord-035067-ic843wr9 292 17 variation variation NN cord-035067-ic843wr9 292 18 from from IN cord-035067-ic843wr9 292 19 6.8 6.8 CD cord-035067-ic843wr9 292 20 % % NN cord-035067-ic843wr9 292 21 to to IN cord-035067-ic843wr9 292 22 61.3 61.3 CD cord-035067-ic843wr9 292 23 % % NN cord-035067-ic843wr9 292 24 . . . cord-035067-ic843wr9 293 1 These these DT cord-035067-ic843wr9 293 2 symptoms symptom NNS cord-035067-ic843wr9 293 3 were be VBD cord-035067-ic843wr9 293 4 diarrhea diarrhea JJ cord-035067-ic843wr9 293 5 ( ( -LRB- cord-035067-ic843wr9 293 6 8.14 8.14 CD cord-035067-ic843wr9 293 7 % % NN cord-035067-ic843wr9 293 8 to to IN cord-035067-ic843wr9 293 9 33.7 33.7 CD cord-035067-ic843wr9 293 10 % % NN cord-035067-ic843wr9 293 11 ) ) -RRB- cord-035067-ic843wr9 293 12 , , , cord-035067-ic843wr9 293 13 nausea nausea NN cord-035067-ic843wr9 293 14 / / SYM cord-035067-ic843wr9 293 15 vomiting vomiting NN cord-035067-ic843wr9 293 16 ( ( -LRB- cord-035067-ic843wr9 293 17 1.53 1.53 CD cord-035067-ic843wr9 293 18 % % NN cord-035067-ic843wr9 293 19 to to IN cord-035067-ic843wr9 293 20 26.4 26.4 CD cord-035067-ic843wr9 293 21 % % NN cord-035067-ic843wr9 293 22 ) ) -RRB- cord-035067-ic843wr9 293 23 , , , cord-035067-ic843wr9 293 24 anorexia anorexia NN cord-035067-ic843wr9 293 25 ( ( -LRB- cord-035067-ic843wr9 293 26 12.1 12.1 CD cord-035067-ic843wr9 293 27 % % NN cord-035067-ic843wr9 293 28 to to IN cord-035067-ic843wr9 293 29 40.0 40.0 CD cord-035067-ic843wr9 293 30 % % NN cord-035067-ic843wr9 293 31 ) ) -RRB- cord-035067-ic843wr9 293 32 , , , cord-035067-ic843wr9 293 33 and and CC cord-035067-ic843wr9 293 34 abdominal abdominal JJ cord-035067-ic843wr9 293 35 pain pain NN cord-035067-ic843wr9 293 36 ( ( -LRB- cord-035067-ic843wr9 293 37 0 0 CD cord-035067-ic843wr9 293 38 % % NN cord-035067-ic843wr9 293 39 to to TO cord-035067-ic843wr9 293 40 14.5 14.5 CD cord-035067-ic843wr9 293 41 % % NN cord-035067-ic843wr9 293 42 ) ) -RRB- cord-035067-ic843wr9 293 43 . . . cord-035067-ic843wr9 294 1 This this DT cord-035067-ic843wr9 294 2 important important JJ cord-035067-ic843wr9 294 3 variation variation NN cord-035067-ic843wr9 294 4 demands demand VBZ cord-035067-ic843wr9 294 5 larger large JJR cord-035067-ic843wr9 294 6 studies study NNS cord-035067-ic843wr9 294 7 , , , cord-035067-ic843wr9 294 8 with with IN cord-035067-ic843wr9 294 9 more more JJR cord-035067-ic843wr9 294 10 patients patient NNS cord-035067-ic843wr9 294 11 and and CC cord-035067-ic843wr9 294 12 from from IN cord-035067-ic843wr9 294 13 various various JJ cord-035067-ic843wr9 294 14 countries country NNS cord-035067-ic843wr9 294 15 . . . cord-035067-ic843wr9 295 1 As as IN cord-035067-ic843wr9 295 2 to to IN cord-035067-ic843wr9 295 3 the the DT cord-035067-ic843wr9 295 4 possibility possibility NN cord-035067-ic843wr9 295 5 of of IN cord-035067-ic843wr9 295 6 fecal fecal JJ cord-035067-ic843wr9 295 7 - - HYPH cord-035067-ic843wr9 295 8 oral oral JJ cord-035067-ic843wr9 295 9 transmission transmission NN cord-035067-ic843wr9 295 10 , , , cord-035067-ic843wr9 295 11 the the DT cord-035067-ic843wr9 295 12 presence presence NN cord-035067-ic843wr9 295 13 of of IN cord-035067-ic843wr9 295 14 viral viral JJ cord-035067-ic843wr9 295 15 RNA RNA NNP cord-035067-ic843wr9 295 16 was be VBD cord-035067-ic843wr9 295 17 tested test VBN cord-035067-ic843wr9 295 18 little little JJ cord-035067-ic843wr9 295 19 , , , cord-035067-ic843wr9 295 20 but but CC cord-035067-ic843wr9 295 21 was be VBD cord-035067-ic843wr9 295 22 positive positive JJ cord-035067-ic843wr9 295 23 between between IN cord-035067-ic843wr9 295 24 0 0 CD cord-035067-ic843wr9 295 25 % % NN cord-035067-ic843wr9 295 26 and and CC cord-035067-ic843wr9 295 27 48.1 48.1 CD cord-035067-ic843wr9 295 28 % % NN cord-035067-ic843wr9 295 29 . . . cord-035067-ic843wr9 296 1 These these DT cord-035067-ic843wr9 296 2 data datum NNS cord-035067-ic843wr9 296 3 also also RB cord-035067-ic843wr9 296 4 varied vary VBD cord-035067-ic843wr9 296 5 a a DT cord-035067-ic843wr9 296 6 lot lot NN cord-035067-ic843wr9 296 7 , , , cord-035067-ic843wr9 296 8 preventing prevent VBG cord-035067-ic843wr9 296 9 any any DT cord-035067-ic843wr9 296 10 conclusion conclusion NN cord-035067-ic843wr9 296 11 about about IN cord-035067-ic843wr9 296 12 them -PRON- PRP cord-035067-ic843wr9 296 13 , , , cord-035067-ic843wr9 296 14 but but CC cord-035067-ic843wr9 296 15 they -PRON- PRP cord-035067-ic843wr9 296 16 should should MD cord-035067-ic843wr9 296 17 also also RB cord-035067-ic843wr9 296 18 be be VB cord-035067-ic843wr9 296 19 studied study VBN cord-035067-ic843wr9 296 20 further further RB cord-035067-ic843wr9 296 21 so so IN cord-035067-ic843wr9 296 22 that that IN cord-035067-ic843wr9 296 23 preventive preventive JJ cord-035067-ic843wr9 296 24 measures measure NNS cord-035067-ic843wr9 296 25 can can MD cord-035067-ic843wr9 296 26 be be VB cord-035067-ic843wr9 296 27 taken take VBN cord-035067-ic843wr9 296 28 . . . cord-035067-ic843wr9 297 1 The the DT cord-035067-ic843wr9 297 2 RNA RNA NNP cord-035067-ic843wr9 297 3 of of IN cord-035067-ic843wr9 297 4 the the DT cord-035067-ic843wr9 297 5 virus virus NN cord-035067-ic843wr9 297 6 in in IN cord-035067-ic843wr9 297 7 feces fece NNS cord-035067-ic843wr9 297 8 does do VBZ cord-035067-ic843wr9 297 9 not not RB cord-035067-ic843wr9 297 10 necessarily necessarily RB cord-035067-ic843wr9 297 11 indicate indicate VB cord-035067-ic843wr9 297 12 that that IN cord-035067-ic843wr9 297 13 there there EX cord-035067-ic843wr9 297 14 is be VBZ cord-035067-ic843wr9 297 15 fecal fecal JJ cord-035067-ic843wr9 297 16 - - HYPH cord-035067-ic843wr9 297 17 oral oral JJ cord-035067-ic843wr9 297 18 transmission transmission NN cord-035067-ic843wr9 297 19 , , , cord-035067-ic843wr9 297 20 and and CC cord-035067-ic843wr9 297 21 its -PRON- PRP$ cord-035067-ic843wr9 297 22 evaluation evaluation NN cord-035067-ic843wr9 297 23 in in IN cord-035067-ic843wr9 297 24 new new JJ cord-035067-ic843wr9 297 25 studies study NNS cord-035067-ic843wr9 297 26 to to TO cord-035067-ic843wr9 297 27 know know VB cord-035067-ic843wr9 297 28 if if IN cord-035067-ic843wr9 297 29 this this DT cord-035067-ic843wr9 297 30 presence presence NN cord-035067-ic843wr9 297 31 is be VBZ cord-035067-ic843wr9 297 32 infectious infectious JJ cord-035067-ic843wr9 297 33 or or CC cord-035067-ic843wr9 297 34 not not RB cord-035067-ic843wr9 297 35 is be VBZ cord-035067-ic843wr9 297 36 very very RB cord-035067-ic843wr9 297 37 important important JJ cord-035067-ic843wr9 297 38 . . . cord-035067-ic843wr9 298 1 Almeida Almeida NNP cord-035067-ic843wr9 298 2 JF JF NNP cord-035067-ic843wr9 298 3 : : : cord-035067-ic843wr9 299 1 http://orcid.org/0000-0003-3619-3003 http://orcid.org/0000-0003-3619-3003 NNP cord-035067-ic843wr9 299 2 Chehter Chehter NNP cord-035067-ic843wr9 299 3 EZ EZ NNP cord-035067-ic843wr9 299 4 : : : cord-035067-ic843wr9 299 5 http://orcid.org/0000-0002-2409-5871 http://orcid.org/0000-0002-2409-5871 XX cord-035067-ic843wr9 300 1 A a DT cord-035067-ic843wr9 300 2 pneumonia pneumonia NN cord-035067-ic843wr9 300 3 outbreak outbreak NN cord-035067-ic843wr9 300 4 associated associate VBN cord-035067-ic843wr9 300 5 with with IN cord-035067-ic843wr9 300 6 a a DT cord-035067-ic843wr9 300 7 new new JJ cord-035067-ic843wr9 300 8 coronavirus coronavirus NN cord-035067-ic843wr9 300 9 of of IN cord-035067-ic843wr9 300 10 probable probable JJ cord-035067-ic843wr9 300 11 bat bat NN cord-035067-ic843wr9 300 12 origin origin NN cord-035067-ic843wr9 300 13 WHO who WP cord-035067-ic843wr9 300 14 Coronavirus Coronavirus NNP cord-035067-ic843wr9 300 15 Disease Disease NNP cord-035067-ic843wr9 300 16 ( ( -LRB- cord-035067-ic843wr9 300 17 COVID-19 COVID-19 NNP cord-035067-ic843wr9 300 18 ) ) -RRB- cord-035067-ic843wr9 300 19 Dashboard dashboard NN cord-035067-ic843wr9 300 20 [ [ -LRB- cord-035067-ic843wr9 300 21 Internet internet NN cord-035067-ic843wr9 300 22 ] ] -RRB- cord-035067-ic843wr9 300 23 . . . cord-035067-ic843wr9 301 1 Geneva Geneva NNP cord-035067-ic843wr9 301 2 : : : cord-035067-ic843wr9 302 1 World World NNP cord-035067-ic843wr9 302 2 Health Health NNP cord-035067-ic843wr9 302 3 Organization Organization NNP cord-035067-ic843wr9 302 4 ( ( -LRB- cord-035067-ic843wr9 302 5 WHO who WP cord-035067-ic843wr9 302 6 ) ) -RRB- cord-035067-ic843wr9 302 7 Hosts Hosts NNPS cord-035067-ic843wr9 302 8 and and CC cord-035067-ic843wr9 302 9 Sources Sources NNPS cord-035067-ic843wr9 302 10 of of IN cord-035067-ic843wr9 302 11 Endemic Endemic NNP cord-035067-ic843wr9 302 12 Human Human NNP cord-035067-ic843wr9 302 13 Coronaviruses Coronaviruses NNPS cord-035067-ic843wr9 303 1 The the DT cord-035067-ic843wr9 303 2 proximal proximal JJ cord-035067-ic843wr9 303 3 origin origin NN cord-035067-ic843wr9 303 4 of of IN cord-035067-ic843wr9 303 5 SARS SARS NNP cord-035067-ic843wr9 303 6 - - HYPH cord-035067-ic843wr9 303 7 CoV-2 CoV-2 NNP cord-035067-ic843wr9 304 1 Addressing address VBG cord-035067-ic843wr9 304 2 multiple multiple JJ cord-035067-ic843wr9 304 3 gastroenterological gastroenterological JJ cord-035067-ic843wr9 304 4 aspects aspect NNS cord-035067-ic843wr9 304 5 of of IN cord-035067-ic843wr9 304 6 COVID-19 covid-19 JJ cord-035067-ic843wr9 304 7 Evidence evidence NN cord-035067-ic843wr9 304 8 for for IN cord-035067-ic843wr9 304 9 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 304 10 infection infection NN cord-035067-ic843wr9 304 11 of of IN cord-035067-ic843wr9 304 12 SARS SARS NNP cord-035067-ic843wr9 304 13 - - HYPH cord-035067-ic843wr9 304 14 CoV-2 CoV-2 NNP cord-035067-ic843wr9 304 15 Is be VBZ cord-035067-ic843wr9 304 16 SARS SARS NNP cord-035067-ic843wr9 304 17 - - HYPH cord-035067-ic843wr9 304 18 CoV-2 CoV-2 NNP cord-035067-ic843wr9 305 1 Also also RB cord-035067-ic843wr9 305 2 an an DT cord-035067-ic843wr9 305 3 enteric enteric JJ cord-035067-ic843wr9 305 4 pathogen pathogen NN cord-035067-ic843wr9 305 5 with with IN cord-035067-ic843wr9 305 6 potential potential JJ cord-035067-ic843wr9 305 7 fecaloral fecaloral JJ cord-035067-ic843wr9 305 8 transmission transmission NN cord-035067-ic843wr9 305 9 : : : cord-035067-ic843wr9 305 10 a a DT cord-035067-ic843wr9 305 11 covid-19 covid-19 NN cord-035067-ic843wr9 305 12 virological virological JJ cord-035067-ic843wr9 305 13 and and CC cord-035067-ic843wr9 305 14 clinical clinical JJ cord-035067-ic843wr9 305 15 review review NN cord-035067-ic843wr9 305 16 Electronic Electronic NNP cord-035067-ic843wr9 305 17 address address NN cord-035067-ic843wr9 305 18 : : : cord-035067-ic843wr9 305 19 ewilson@gastro.org ewilson@gastro.org NNP cord-035067-ic843wr9 305 20 . . . cord-035067-ic843wr9 306 1 AGA AGA NNP cord-035067-ic843wr9 306 2 Institute Institute NNP cord-035067-ic843wr9 306 3 rapid rapid JJ cord-035067-ic843wr9 306 4 review review NN cord-035067-ic843wr9 306 5 of of IN cord-035067-ic843wr9 306 6 the the DT cord-035067-ic843wr9 306 7 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 306 8 and and CC cord-035067-ic843wr9 306 9 liver liver JJ cord-035067-ic843wr9 306 10 manifestations manifestation NNS cord-035067-ic843wr9 306 11 of of IN cord-035067-ic843wr9 306 12 covid-19 covid-19 NNP cord-035067-ic843wr9 306 13 , , , cord-035067-ic843wr9 306 14 meta meta NNP cord-035067-ic843wr9 306 15 - - HYPH cord-035067-ic843wr9 306 16 analysis analysis NNP cord-035067-ic843wr9 306 17 of of IN cord-035067-ic843wr9 306 18 international international JJ cord-035067-ic843wr9 306 19 data datum NNS cord-035067-ic843wr9 306 20 , , , cord-035067-ic843wr9 306 21 and and CC cord-035067-ic843wr9 306 22 recommendations recommendation NNS cord-035067-ic843wr9 306 23 for for IN cord-035067-ic843wr9 306 24 the the DT cord-035067-ic843wr9 306 25 consultative consultative JJ cord-035067-ic843wr9 306 26 management management NN cord-035067-ic843wr9 306 27 of of IN cord-035067-ic843wr9 306 28 patients patient NNS cord-035067-ic843wr9 306 29 with with IN cord-035067-ic843wr9 306 30 COVID-19 COVID-19 NNP cord-035067-ic843wr9 306 31 Covid-19 Covid-19 NNP cord-035067-ic843wr9 306 32 , , , cord-035067-ic843wr9 306 33 coronavirus coronavirus NN cord-035067-ic843wr9 306 34 , , , cord-035067-ic843wr9 306 35 SARS SARS NNP cord-035067-ic843wr9 306 36 - - HYPH cord-035067-ic843wr9 306 37 CoV-2 CoV-2 NNP cord-035067-ic843wr9 306 38 and and CC cord-035067-ic843wr9 306 39 the the DT cord-035067-ic843wr9 306 40 small small JJ cord-035067-ic843wr9 306 41 bowel bowel NN cord-035067-ic843wr9 306 42 Mucosal Mucosal NNP cord-035067-ic843wr9 306 43 macrophages macrophage NNS cord-035067-ic843wr9 306 44 and and CC cord-035067-ic843wr9 306 45 the the DT cord-035067-ic843wr9 306 46 regulation regulation NN cord-035067-ic843wr9 306 47 of of IN cord-035067-ic843wr9 306 48 immune immune JJ cord-035067-ic843wr9 306 49 responses response NNS cord-035067-ic843wr9 306 50 in in IN cord-035067-ic843wr9 306 51 the the DT cord-035067-ic843wr9 306 52 intestine intestine NN cord-035067-ic843wr9 306 53 Electronic Electronic NNP cord-035067-ic843wr9 306 54 address address NN cord-035067-ic843wr9 306 55 : : : cord-035067-ic843wr9 306 56 lung-network@humancellatlas.org lung-network@humancellatlas.org NNP cord-035067-ic843wr9 306 57 ; ; : cord-035067-ic843wr9 306 58 HCA HCA NNP cord-035067-ic843wr9 306 59 Lung Lung NNP cord-035067-ic843wr9 306 60 Biological Biological NNP cord-035067-ic843wr9 306 61 Network Network NNP cord-035067-ic843wr9 306 62 . . . cord-035067-ic843wr9 307 1 SARS SARS NNP cord-035067-ic843wr9 307 2 - - HYPH cord-035067-ic843wr9 307 3 CoV-2 CoV-2 NNP cord-035067-ic843wr9 307 4 receptor receptor NN cord-035067-ic843wr9 307 5 ACE2 ACE2 NNP cord-035067-ic843wr9 307 6 is be VBZ cord-035067-ic843wr9 307 7 an an DT cord-035067-ic843wr9 307 8 interferon interferon NN cord-035067-ic843wr9 307 9 - - HYPH cord-035067-ic843wr9 307 10 stimulated stimulate VBN cord-035067-ic843wr9 307 11 gene gene NN cord-035067-ic843wr9 307 12 in in IN cord-035067-ic843wr9 307 13 human human JJ cord-035067-ic843wr9 307 14 airway airway NN cord-035067-ic843wr9 307 15 epithelial epithelial JJ cord-035067-ic843wr9 307 16 cells cell NNS cord-035067-ic843wr9 307 17 and and CC cord-035067-ic843wr9 307 18 is be VBZ cord-035067-ic843wr9 307 19 detected detect VBN cord-035067-ic843wr9 307 20 in in IN cord-035067-ic843wr9 307 21 specific specific JJ cord-035067-ic843wr9 307 22 cell cell NN cord-035067-ic843wr9 307 23 subsets subset NNS cord-035067-ic843wr9 307 24 across across IN cord-035067-ic843wr9 307 25 tissues tissue NNS cord-035067-ic843wr9 307 26 ACE-2 ACE-2 NNP cord-035067-ic843wr9 307 27 expression expression NN cord-035067-ic843wr9 307 28 in in IN cord-035067-ic843wr9 307 29 the the DT cord-035067-ic843wr9 307 30 small small JJ cord-035067-ic843wr9 307 31 airway airway NN cord-035067-ic843wr9 307 32 epithelia epithelium NNS cord-035067-ic843wr9 307 33 of of IN cord-035067-ic843wr9 307 34 smokers smoker NNS cord-035067-ic843wr9 307 35 and and CC cord-035067-ic843wr9 307 36 COPD COPD NNP cord-035067-ic843wr9 307 37 Patients patient NNS cord-035067-ic843wr9 307 38 : : : cord-035067-ic843wr9 307 39 Implications implication NNS cord-035067-ic843wr9 307 40 for for IN cord-035067-ic843wr9 307 41 COVID-19 COVID-19 NNP cord-035067-ic843wr9 307 42 COVID-19 COVID-19 NNP cord-035067-ic843wr9 307 43 and and CC cord-035067-ic843wr9 307 44 diabetes diabete VBZ cord-035067-ic843wr9 307 45 : : : cord-035067-ic843wr9 307 46 Knowledge knowledge NN cord-035067-ic843wr9 307 47 in in IN cord-035067-ic843wr9 307 48 progress progress NNP cord-035067-ic843wr9 307 49 Association Association NNP cord-035067-ic843wr9 307 50 of of IN cord-035067-ic843wr9 307 51 angiotensin angiotensin NN cord-035067-ic843wr9 307 52 - - HYPH cord-035067-ic843wr9 307 53 converting convert VBG cord-035067-ic843wr9 307 54 enzyme enzyme NN cord-035067-ic843wr9 307 55 inhibitor inhibitor NN cord-035067-ic843wr9 307 56 or or CC cord-035067-ic843wr9 307 57 angiotensin angiotensin NN cord-035067-ic843wr9 307 58 receptor receptor NN cord-035067-ic843wr9 307 59 blocker blocker NN cord-035067-ic843wr9 307 60 use use VBP cord-035067-ic843wr9 307 61 with with IN cord-035067-ic843wr9 307 62 covid-19 covid-19 JJ cord-035067-ic843wr9 307 63 diagnosis diagnosis NN cord-035067-ic843wr9 307 64 and and CC cord-035067-ic843wr9 307 65 mortality mortality NNP cord-035067-ic843wr9 307 66 Association Association NNP cord-035067-ic843wr9 307 67 of of IN cord-035067-ic843wr9 307 68 renin renin NN cord-035067-ic843wr9 307 69 - - HYPH cord-035067-ic843wr9 307 70 angiotensin angiotensin NN cord-035067-ic843wr9 307 71 system system NN cord-035067-ic843wr9 307 72 inhibitors inhibitor NNS cord-035067-ic843wr9 307 73 with with IN cord-035067-ic843wr9 307 74 severity severity NN cord-035067-ic843wr9 307 75 or or CC cord-035067-ic843wr9 307 76 risk risk NN cord-035067-ic843wr9 307 77 of of IN cord-035067-ic843wr9 307 78 death death NN cord-035067-ic843wr9 307 79 in in IN cord-035067-ic843wr9 307 80 patients patient NNS cord-035067-ic843wr9 307 81 with with IN cord-035067-ic843wr9 307 82 hypertension hypertension NN cord-035067-ic843wr9 307 83 hospitalized hospitalize VBN cord-035067-ic843wr9 307 84 for for IN cord-035067-ic843wr9 307 85 coronavirus coronavirus NN cord-035067-ic843wr9 307 86 disease disease NN cord-035067-ic843wr9 307 87 2019 2019 CD cord-035067-ic843wr9 307 88 ( ( -LRB- cord-035067-ic843wr9 308 1 COVID-19 covid-19 LS cord-035067-ic843wr9 308 2 ) ) -RRB- cord-035067-ic843wr9 308 3 infection infection NN cord-035067-ic843wr9 308 4 in in IN cord-035067-ic843wr9 308 5 Wuhan Wuhan NNP cord-035067-ic843wr9 308 6 , , , cord-035067-ic843wr9 308 7 China China NNP cord-035067-ic843wr9 308 8 Emerging Emerging NNP cord-035067-ic843wr9 308 9 WuHan WuHan NNP cord-035067-ic843wr9 308 10 ( ( -LRB- cord-035067-ic843wr9 308 11 COVID-19 COVID-19 NNP cord-035067-ic843wr9 308 12 ) ) -RRB- cord-035067-ic843wr9 308 13 coronavirus coronavirus NN cord-035067-ic843wr9 308 14 : : : cord-035067-ic843wr9 308 15 glycan glycan NNP cord-035067-ic843wr9 308 16 shield shield NN cord-035067-ic843wr9 308 17 and and CC cord-035067-ic843wr9 308 18 structure structure NN cord-035067-ic843wr9 308 19 prediction prediction NN cord-035067-ic843wr9 308 20 of of IN cord-035067-ic843wr9 308 21 spike spike NN cord-035067-ic843wr9 308 22 glycoprotein glycoprotein NN cord-035067-ic843wr9 308 23 and and CC cord-035067-ic843wr9 308 24 its -PRON- PRP$ cord-035067-ic843wr9 308 25 interaction interaction NN cord-035067-ic843wr9 308 26 with with IN cord-035067-ic843wr9 308 27 human human JJ cord-035067-ic843wr9 308 28 CD26 CD26 NNP cord-035067-ic843wr9 308 29 Characterization characterization NN cord-035067-ic843wr9 308 30 of of IN cord-035067-ic843wr9 308 31 the the DT cord-035067-ic843wr9 308 32 receptor receptor NN cord-035067-ic843wr9 308 33 - - HYPH cord-035067-ic843wr9 308 34 binding bind VBG cord-035067-ic843wr9 308 35 domain domain NN cord-035067-ic843wr9 308 36 ( ( -LRB- cord-035067-ic843wr9 308 37 RBD RBD NNP cord-035067-ic843wr9 308 38 ) ) -RRB- cord-035067-ic843wr9 308 39 of of IN cord-035067-ic843wr9 308 40 2019 2019 CD cord-035067-ic843wr9 308 41 novel novel JJ cord-035067-ic843wr9 308 42 coronavirus coronavirus NN cord-035067-ic843wr9 308 43 : : : cord-035067-ic843wr9 308 44 implication implication NN cord-035067-ic843wr9 308 45 for for IN cord-035067-ic843wr9 308 46 development development NN cord-035067-ic843wr9 308 47 of of IN cord-035067-ic843wr9 308 48 RBD RBD NNP cord-035067-ic843wr9 308 49 protein protein NN cord-035067-ic843wr9 308 50 as as IN cord-035067-ic843wr9 308 51 a a DT cord-035067-ic843wr9 308 52 viral viral JJ cord-035067-ic843wr9 308 53 attachment attachment NN cord-035067-ic843wr9 308 54 inhibitor inhibitor NN cord-035067-ic843wr9 308 55 and and CC cord-035067-ic843wr9 308 56 vaccine vaccine NN cord-035067-ic843wr9 308 57 Epidemiological epidemiological JJ cord-035067-ic843wr9 308 58 , , , cord-035067-ic843wr9 308 59 clinical clinical JJ cord-035067-ic843wr9 308 60 and and CC cord-035067-ic843wr9 308 61 virological virological JJ cord-035067-ic843wr9 308 62 characteristics characteristic NNS cord-035067-ic843wr9 308 63 of of IN cord-035067-ic843wr9 308 64 74 74 CD cord-035067-ic843wr9 308 65 cases case NNS cord-035067-ic843wr9 308 66 of of IN cord-035067-ic843wr9 308 67 coronavirus coronavirus NN cord-035067-ic843wr9 308 68 - - HYPH cord-035067-ic843wr9 308 69 infected infect VBN cord-035067-ic843wr9 308 70 disease disease NN cord-035067-ic843wr9 308 71 2019 2019 CD cord-035067-ic843wr9 308 72 ( ( -LRB- cord-035067-ic843wr9 308 73 COVID-19 covid-19 VB cord-035067-ic843wr9 308 74 ) ) -RRB- cord-035067-ic843wr9 308 75 with with IN cord-035067-ic843wr9 308 76 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 308 77 symptoms symptom NNS cord-035067-ic843wr9 308 78 Gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 308 79 symptoms symptom NNS cord-035067-ic843wr9 308 80 of of IN cord-035067-ic843wr9 308 81 95 95 CD cord-035067-ic843wr9 308 82 cases case NNS cord-035067-ic843wr9 308 83 with with IN cord-035067-ic843wr9 308 84 SARS SARS NNP cord-035067-ic843wr9 308 85 - - HYPH cord-035067-ic843wr9 308 86 CoV-2 CoV-2 NNP cord-035067-ic843wr9 308 87 infection infection NN cord-035067-ic843wr9 308 88 Clinical clinical JJ cord-035067-ic843wr9 308 89 characteristics characteristic NNS cord-035067-ic843wr9 308 90 of of IN cord-035067-ic843wr9 308 91 COVID-19 covid-19 JJ cord-035067-ic843wr9 308 92 patients patient NNS cord-035067-ic843wr9 308 93 with with IN cord-035067-ic843wr9 308 94 digestive digestive JJ cord-035067-ic843wr9 308 95 symptoms symptom NNS cord-035067-ic843wr9 308 96 in in IN cord-035067-ic843wr9 308 97 Hubei Hubei NNP cord-035067-ic843wr9 308 98 , , , cord-035067-ic843wr9 309 1 China China NNP cord-035067-ic843wr9 309 2 Enteric enteric JJ cord-035067-ic843wr9 309 3 involvement involvement NN cord-035067-ic843wr9 309 4 in in IN cord-035067-ic843wr9 309 5 hospitalised hospitalise VBN cord-035067-ic843wr9 309 6 patients patient NNS cord-035067-ic843wr9 309 7 with with IN cord-035067-ic843wr9 309 8 COVID-19 covid-19 JJ cord-035067-ic843wr9 309 9 outside outside IN cord-035067-ic843wr9 309 10 Wuhan Wuhan NNP cord-035067-ic843wr9 309 11 Prevalence prevalence NN cord-035067-ic843wr9 309 12 and and CC cord-035067-ic843wr9 309 13 characteristics characteristic NNS cord-035067-ic843wr9 309 14 of of IN cord-035067-ic843wr9 309 15 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 309 16 symptoms symptom NNS cord-035067-ic843wr9 309 17 in in IN cord-035067-ic843wr9 309 18 patients patient NNS cord-035067-ic843wr9 309 19 with with IN cord-035067-ic843wr9 309 20 SARS SARS NNP cord-035067-ic843wr9 309 21 - - HYPH cord-035067-ic843wr9 309 22 CoV-2 CoV-2 NNP cord-035067-ic843wr9 309 23 infection infection NN cord-035067-ic843wr9 309 24 in in IN cord-035067-ic843wr9 309 25 the the DT cord-035067-ic843wr9 309 26 United United NNP cord-035067-ic843wr9 309 27 States States NNP cord-035067-ic843wr9 309 28 : : : cord-035067-ic843wr9 309 29 a a DT cord-035067-ic843wr9 309 30 multicenter multicenter JJ cord-035067-ic843wr9 309 31 cohort cohort NN cord-035067-ic843wr9 309 32 study study NN cord-035067-ic843wr9 309 33 Gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 309 34 symptoms symptom NNS cord-035067-ic843wr9 309 35 and and CC cord-035067-ic843wr9 309 36 COVID-19 covid-19 NN cord-035067-ic843wr9 310 1 : : : cord-035067-ic843wr9 310 2 case case NN cord-035067-ic843wr9 310 3 - - HYPH cord-035067-ic843wr9 310 4 control control NN cord-035067-ic843wr9 310 5 study study NN cord-035067-ic843wr9 310 6 from from IN cord-035067-ic843wr9 310 7 the the DT cord-035067-ic843wr9 310 8 United United NNP cord-035067-ic843wr9 310 9 States States NNP cord-035067-ic843wr9 310 10 High high JJ cord-035067-ic843wr9 310 11 prevalence prevalence NN cord-035067-ic843wr9 310 12 of of IN cord-035067-ic843wr9 310 13 concurrent concurrent JJ cord-035067-ic843wr9 310 14 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 310 15 manifestations manifestation NNS cord-035067-ic843wr9 310 16 in in IN cord-035067-ic843wr9 310 17 patients patient NNS cord-035067-ic843wr9 310 18 with with IN cord-035067-ic843wr9 310 19 SARS SARS NNP cord-035067-ic843wr9 310 20 - - HYPH cord-035067-ic843wr9 310 21 CoV-2 CoV-2 NNP cord-035067-ic843wr9 310 22 : : : cord-035067-ic843wr9 310 23 early early JJ cord-035067-ic843wr9 310 24 experience experience NN cord-035067-ic843wr9 310 25 from from IN cord-035067-ic843wr9 310 26 California California NNP cord-035067-ic843wr9 310 27 Clinical clinical JJ cord-035067-ic843wr9 310 28 characteristics characteristic NNS cord-035067-ic843wr9 310 29 of of IN cord-035067-ic843wr9 310 30 140 140 CD cord-035067-ic843wr9 310 31 patients patient NNS cord-035067-ic843wr9 310 32 infected infect VBN cord-035067-ic843wr9 310 33 with with IN cord-035067-ic843wr9 310 34 SARS SARS NNP cord-035067-ic843wr9 310 35 - - HYPH cord-035067-ic843wr9 310 36 CoV-2 CoV-2 NNP cord-035067-ic843wr9 310 37 in in IN cord-035067-ic843wr9 310 38 Wuhan Wuhan NNP cord-035067-ic843wr9 310 39 Effect Effect NNP cord-035067-ic843wr9 310 40 of of IN cord-035067-ic843wr9 310 41 gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 310 42 symptoms symptom NNS cord-035067-ic843wr9 310 43 on on IN cord-035067-ic843wr9 310 44 patients patient NNS cord-035067-ic843wr9 310 45 infected infect VBN cord-035067-ic843wr9 310 46 with with IN cord-035067-ic843wr9 310 47 COVID-19 COVID-19 NNP cord-035067-ic843wr9 310 48 Gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 310 49 manifestations manifestation NNS cord-035067-ic843wr9 310 50 of of IN cord-035067-ic843wr9 310 51 SARS SARS NNP cord-035067-ic843wr9 310 52 - - HYPH cord-035067-ic843wr9 310 53 CoV-2 CoV-2 NNP cord-035067-ic843wr9 310 54 infection infection NN cord-035067-ic843wr9 310 55 and and CC cord-035067-ic843wr9 310 56 virus virus NN cord-035067-ic843wr9 310 57 load load NN cord-035067-ic843wr9 310 58 in in IN cord-035067-ic843wr9 310 59 fecal fecal JJ cord-035067-ic843wr9 310 60 samples sample NNS cord-035067-ic843wr9 310 61 from from IN cord-035067-ic843wr9 310 62 the the DT cord-035067-ic843wr9 310 63 Hong Hong NNP cord-035067-ic843wr9 310 64 Kong Kong NNP cord-035067-ic843wr9 310 65 cohort cohort NN cord-035067-ic843wr9 310 66 and and CC cord-035067-ic843wr9 310 67 systematic systematic JJ cord-035067-ic843wr9 310 68 review review NN cord-035067-ic843wr9 310 69 and and CC cord-035067-ic843wr9 310 70 meta meta NNP cord-035067-ic843wr9 310 71 - - HYPH cord-035067-ic843wr9 310 72 analysis analysis NN cord-035067-ic843wr9 310 73 Imaging Imaging NNP cord-035067-ic843wr9 310 74 and and CC cord-035067-ic843wr9 310 75 clinical clinical JJ cord-035067-ic843wr9 310 76 features feature NNS cord-035067-ic843wr9 310 77 of of IN cord-035067-ic843wr9 310 78 patients patient NNS cord-035067-ic843wr9 310 79 with with IN cord-035067-ic843wr9 310 80 2019 2019 CD cord-035067-ic843wr9 310 81 novel novel NN cord-035067-ic843wr9 310 82 coronavirus coronavirus NN cord-035067-ic843wr9 310 83 SARS SARS NNP cord-035067-ic843wr9 310 84 - - HYPH cord-035067-ic843wr9 310 85 CoV-2 CoV-2 NNP cord-035067-ic843wr9 310 86 : : : cord-035067-ic843wr9 310 87 a a DT cord-035067-ic843wr9 310 88 systematic systematic JJ cord-035067-ic843wr9 310 89 review review NN cord-035067-ic843wr9 310 90 and and CC cord-035067-ic843wr9 310 91 meta meta NNP cord-035067-ic843wr9 310 92 - - HYPH cord-035067-ic843wr9 310 93 analysis analysis NNP cord-035067-ic843wr9 310 94 COVID-19 covid-19 CD cord-035067-ic843wr9 310 95 patients patient NNS cord-035067-ic843wr9 310 96 ' ' POS cord-035067-ic843wr9 310 97 clinical clinical JJ cord-035067-ic843wr9 310 98 characteristics characteristic NNS cord-035067-ic843wr9 310 99 , , , cord-035067-ic843wr9 310 100 discharge discharge NN cord-035067-ic843wr9 310 101 rate rate NN cord-035067-ic843wr9 310 102 , , , cord-035067-ic843wr9 310 103 and and CC cord-035067-ic843wr9 310 104 fatality fatality NN cord-035067-ic843wr9 310 105 rate rate NN cord-035067-ic843wr9 310 106 of of IN cord-035067-ic843wr9 310 107 meta meta JJ cord-035067-ic843wr9 310 108 - - HYPH cord-035067-ic843wr9 310 109 analysis analysis NN cord-035067-ic843wr9 310 110 Gastrointestinal gastrointestinal JJ cord-035067-ic843wr9 310 111 infection infection NN cord-035067-ic843wr9 310 112 could could MD cord-035067-ic843wr9 310 113 be be VB cord-035067-ic843wr9 310 114 new new JJ cord-035067-ic843wr9 310 115 focus focus NN cord-035067-ic843wr9 310 116 for for IN cord-035067-ic843wr9 310 117 coronavirus coronavirus NN cord-035067-ic843wr9 310 118 diagnosis diagnosis NN cord-035067-ic843wr9 310 119 Individual individual JJ cord-035067-ic843wr9 310 120 variation variation NN cord-035067-ic843wr9 310 121 of of IN cord-035067-ic843wr9 310 122 the the DT cord-035067-ic843wr9 310 123 SARS SARS NNP cord-035067-ic843wr9 310 124 - - HYPH cord-035067-ic843wr9 310 125 CoV2 CoV2 NNP cord-035067-ic843wr9 310 126 receptor receptor NN cord-035067-ic843wr9 310 127 ACE2 ACE2 NNP cord-035067-ic843wr9 310 128 gene gene NN cord-035067-ic843wr9 310 129 expression expression NN cord-035067-ic843wr9 310 130 and and CC cord-035067-ic843wr9 310 131 regulation regulation NN