id	sid	tid	token	lemma	pos
cord-262786-otxpc46a	1	1	key	key	JJ
cord-262786-otxpc46a	2	1	:	:	:
cord-262786-otxpc46a	2	2	cord-262786-otxpc46a	cord-262786-otxpc46a	CC
cord-262786-otxpc46a	2	3	authors	author	NNS
cord-262786-otxpc46a	2	4	:	:	:
cord-262786-otxpc46a	2	5	Mohammadi	Mohammadi	NNP
cord-262786-otxpc46a	2	6	,	,	,
cord-262786-otxpc46a	2	7	Soheil	Soheil	NNP
cord-262786-otxpc46a	2	8	;	;	:
cord-262786-otxpc46a	2	9	Moosaie	Moosaie	NNP
cord-262786-otxpc46a	2	10	,	,	,
cord-262786-otxpc46a	2	11	Fatemeh	Fatemeh	NNP
cord-262786-otxpc46a	2	12	;	;	:
cord-262786-otxpc46a	2	13	Aarabi	Aarabi	NNP
cord-262786-otxpc46a	2	14	,	,	,
cord-262786-otxpc46a	2	15	Mohammad	Mohammad	NNP
cord-262786-otxpc46a	2	16	Hadi	Hadi	NNP
cord-262786-otxpc46a	3	1	title	title	NN
cord-262786-otxpc46a	3	2	:	:	:
cord-262786-otxpc46a	4	1	Understanding	understand	VBG
cord-262786-otxpc46a	4	2	the	the	DT
cord-262786-otxpc46a	4	3	Immunologic	Immunologic	NNP
cord-262786-otxpc46a	4	4	Characteristics	Characteristics	NNPS
cord-262786-otxpc46a	4	5	of	of	IN
cord-262786-otxpc46a	4	6	Neurologic	Neurologic	NNP
cord-262786-otxpc46a	4	7	Manifestations	Manifestations	NNPS
cord-262786-otxpc46a	4	8	of	of	IN
cord-262786-otxpc46a	4	9	SARS	SARS	NNP
cord-262786-otxpc46a	4	10	-	-	HYPH
cord-262786-otxpc46a	4	11	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	4	12	and	and	CC
cord-262786-otxpc46a	4	13	Potential	Potential	NNP
cord-262786-otxpc46a	4	14	Immunological	Immunological	NNP
cord-262786-otxpc46a	4	15	Mechanisms	Mechanisms	NNPS
cord-262786-otxpc46a	4	16	date	date	NN
cord-262786-otxpc46a	5	1	:	:	:
cord-262786-otxpc46a	5	2	2020	2020	CD
cord-262786-otxpc46a	5	3	-	-	HYPH
cord-262786-otxpc46a	5	4	09	09	CD
cord-262786-otxpc46a	5	5	-	-	HYPH
cord-262786-otxpc46a	5	6	01	01	CD
cord-262786-otxpc46a	5	7	journal	journal	NN
cord-262786-otxpc46a	5	8	:	:	:
cord-262786-otxpc46a	6	1	Mol	Mol	NNP
cord-262786-otxpc46a	6	2	Neurobiol	Neurobiol	NNP
cord-262786-otxpc46a	6	3	DOI	DOI	NNP
cord-262786-otxpc46a	6	4	:	:	:
cord-262786-otxpc46a	7	1	10.1007	10.1007	CD
cord-262786-otxpc46a	7	2	/	/	SYM
cord-262786-otxpc46a	7	3	s12035	s12035	NN
cord-262786-otxpc46a	7	4	-	-	HYPH
cord-262786-otxpc46a	7	5	020	020	CD
cord-262786-otxpc46a	7	6	-	-	HYPH
cord-262786-otxpc46a	7	7	02094-y	02094-y	CD
cord-262786-otxpc46a	7	8	sha	sha	NNP
cord-262786-otxpc46a	7	9	:	:	:
cord-262786-otxpc46a	8	1	784e5ddb8ef71c0a9effbce58504af6d0fbe8586	784e5ddb8ef71c0a9effbce58504af6d0fbe8586	NNP
cord-262786-otxpc46a	8	2	doc_id	doc_id	CD
cord-262786-otxpc46a	8	3	:	:	:
cord-262786-otxpc46a	9	1	262786	262786	CD
cord-262786-otxpc46a	9	2	cord_uid	cord_uid	NNS
cord-262786-otxpc46a	9	3	:	:	:
cord-262786-otxpc46a	9	4	otxpc46a	otxpc46a	NNS
cord-262786-otxpc46a	9	5	Similar	similar	JJ
cord-262786-otxpc46a	9	6	to	to	IN
cord-262786-otxpc46a	9	7	its	-PRON-	PRP$
cord-262786-otxpc46a	9	8	predecessors	predecessor	NNS
cord-262786-otxpc46a	9	9	,	,	,
cord-262786-otxpc46a	9	10	coronavirus	coronavirus	NN
cord-262786-otxpc46a	9	11	disease	disease	NN
cord-262786-otxpc46a	9	12	2019	2019	CD
cord-262786-otxpc46a	9	13	(	(	-LRB-
cord-262786-otxpc46a	9	14	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	9	15	)	)	-RRB-
cord-262786-otxpc46a	10	1	exhibits	exhibit	VBZ
cord-262786-otxpc46a	10	2	neurotrophic	neurotrophic	NN
cord-262786-otxpc46a	10	3	properties	property	NNS
cord-262786-otxpc46a	10	4	,	,	,
cord-262786-otxpc46a	10	5	which	which	WDT
cord-262786-otxpc46a	10	6	lead	lead	VBP
cord-262786-otxpc46a	10	7	to	to	IN
cord-262786-otxpc46a	10	8	progression	progression	NN
cord-262786-otxpc46a	10	9	of	of	IN
cord-262786-otxpc46a	10	10	neurologic	neurologic	JJ
cord-262786-otxpc46a	10	11	sequelae	sequela	NNS
cord-262786-otxpc46a	10	12	.	.	.
cord-262786-otxpc46a	11	1	Besides	besides	IN
cord-262786-otxpc46a	11	2	direct	direct	JJ
cord-262786-otxpc46a	11	3	viral	viral	JJ
cord-262786-otxpc46a	11	4	invasion	invasion	NN
cord-262786-otxpc46a	11	5	to	to	IN
cord-262786-otxpc46a	11	6	the	the	DT
cord-262786-otxpc46a	11	7	central	central	JJ
cord-262786-otxpc46a	11	8	nervous	nervous	JJ
cord-262786-otxpc46a	11	9	system	system	NN
cord-262786-otxpc46a	11	10	(	(	-LRB-
cord-262786-otxpc46a	11	11	CNS	CNS	NNP
cord-262786-otxpc46a	11	12	)	)	-RRB-
cord-262786-otxpc46a	11	13	,	,	,
cord-262786-otxpc46a	11	14	indirect	indirect	JJ
cord-262786-otxpc46a	11	15	CNS	CNS	NNP
cord-262786-otxpc46a	11	16	involvement	involvement	NN
cord-262786-otxpc46a	11	17	through	through	IN
cord-262786-otxpc46a	11	18	viral	viral	RB
cord-262786-otxpc46a	11	19	-	-	HYPH
cord-262786-otxpc46a	11	20	mediated	mediate	VBN
cord-262786-otxpc46a	11	21	immune	immune	JJ
cord-262786-otxpc46a	11	22	response	response	NN
cord-262786-otxpc46a	11	23	is	be	VBZ
cord-262786-otxpc46a	11	24	plausible	plausible	JJ
cord-262786-otxpc46a	11	25	.	.	.
cord-262786-otxpc46a	12	1	Aberrant	aberrant	JJ
cord-262786-otxpc46a	12	2	immune	immune	JJ
cord-262786-otxpc46a	12	3	pathways	pathway	NNS
cord-262786-otxpc46a	12	4	such	such	JJ
cord-262786-otxpc46a	12	5	as	as	IN
cord-262786-otxpc46a	12	6	extreme	extreme	JJ
cord-262786-otxpc46a	12	7	release	release	NN
cord-262786-otxpc46a	12	8	of	of	IN
cord-262786-otxpc46a	12	9	cytokines	cytokine	NNS
cord-262786-otxpc46a	12	10	(	(	-LRB-
cord-262786-otxpc46a	12	11	cytokine	cytokine	NN
cord-262786-otxpc46a	12	12	storm	storm	NN
cord-262786-otxpc46a	12	13	)	)	-RRB-
cord-262786-otxpc46a	12	14	,	,	,
cord-262786-otxpc46a	12	15	autoimmunity	autoimmunity	NN
cord-262786-otxpc46a	12	16	mediated	mediate	VBN
cord-262786-otxpc46a	12	17	by	by	IN
cord-262786-otxpc46a	12	18	cross	cross	NN
cord-262786-otxpc46a	12	19	-	-	NN
cord-262786-otxpc46a	12	20	reactivity	reactivity	NN
cord-262786-otxpc46a	12	21	between	between	IN
cord-262786-otxpc46a	12	22	CNS	CNS	NNP
cord-262786-otxpc46a	12	23	components	component	NNS
cord-262786-otxpc46a	12	24	and	and	CC
cord-262786-otxpc46a	12	25	viral	viral	JJ
cord-262786-otxpc46a	12	26	particles	particle	NNS
cord-262786-otxpc46a	12	27	,	,	,
cord-262786-otxpc46a	12	28	and	and	CC
cord-262786-otxpc46a	12	29	microglial	microglial	JJ
cord-262786-otxpc46a	12	30	activation	activation	NN
cord-262786-otxpc46a	12	31	propagate	propagate	VBP
cord-262786-otxpc46a	12	32	CNS	CNS	NNP
cord-262786-otxpc46a	12	33	damage	damage	NN
cord-262786-otxpc46a	12	34	in	in	IN
cord-262786-otxpc46a	12	35	these	these	DT
cord-262786-otxpc46a	12	36	patients	patient	NNS
cord-262786-otxpc46a	12	37	.	.	.
cord-262786-otxpc46a	13	1	Here	here	RB
cord-262786-otxpc46a	13	2	,	,	,
cord-262786-otxpc46a	13	3	we	-PRON-	PRP
cord-262786-otxpc46a	13	4	review	review	VBP
cord-262786-otxpc46a	13	5	the	the	DT
cord-262786-otxpc46a	13	6	currently	currently	RB
cord-262786-otxpc46a	13	7	available	available	JJ
cord-262786-otxpc46a	13	8	evidence	evidence	NN
cord-262786-otxpc46a	13	9	to	to	TO
cord-262786-otxpc46a	13	10	discuss	discuss	VB
cord-262786-otxpc46a	13	11	the	the	DT
cord-262786-otxpc46a	13	12	plausible	plausible	JJ
cord-262786-otxpc46a	13	13	immunologic	immunologic	JJ
cord-262786-otxpc46a	13	14	pathways	pathway	NNS
cord-262786-otxpc46a	13	15	that	that	WDT
cord-262786-otxpc46a	13	16	may	may	MD
cord-262786-otxpc46a	13	17	contribute	contribute	VB
cord-262786-otxpc46a	13	18	to	to	IN
cord-262786-otxpc46a	13	19	the	the	DT
cord-262786-otxpc46a	13	20	development	development	NN
cord-262786-otxpc46a	13	21	of	of	IN
cord-262786-otxpc46a	13	22	COVID-19	covid-19	JJ
cord-262786-otxpc46a	13	23	neurological	neurological	JJ
cord-262786-otxpc46a	13	24	complications	complication	NNS
cord-262786-otxpc46a	13	25	,	,	,
cord-262786-otxpc46a	13	26	namely	namely	RB
cord-262786-otxpc46a	13	27	Alzheimer	Alzheimer	NNP
cord-262786-otxpc46a	13	28	’s	’s	POS
cord-262786-otxpc46a	13	29	disease	disease	NN
cord-262786-otxpc46a	13	30	,	,	,
cord-262786-otxpc46a	13	31	Parkinson	Parkinson	NNP
cord-262786-otxpc46a	13	32	’s	’s	POS
cord-262786-otxpc46a	13	33	disease	disease	NN
cord-262786-otxpc46a	13	34	,	,	,
cord-262786-otxpc46a	13	35	stroke	stroke	NN
cord-262786-otxpc46a	13	36	,	,	,
cord-262786-otxpc46a	13	37	multiple	multiple	JJ
cord-262786-otxpc46a	13	38	sclerosis	sclerosis	NN
cord-262786-otxpc46a	13	39	,	,	,
cord-262786-otxpc46a	13	40	Guillain	Guillain	NNP
cord-262786-otxpc46a	13	41	-	-	HYPH
cord-262786-otxpc46a	13	42	Barre	Barre	NNP
cord-262786-otxpc46a	13	43	syndrome	syndrome	NN
cord-262786-otxpc46a	13	44	,	,	,
cord-262786-otxpc46a	13	45	seizure	seizure	NN
cord-262786-otxpc46a	13	46	,	,	,
cord-262786-otxpc46a	13	47	and	and	CC
cord-262786-otxpc46a	13	48	brainstem	brainstem	NN
cord-262786-otxpc46a	13	49	involvement	involvement	NN
cord-262786-otxpc46a	13	50	.	.	.
cord-262786-otxpc46a	14	1	In	in	IN
cord-262786-otxpc46a	14	2	December	December	NNP
cord-262786-otxpc46a	14	3	2019	2019	CD
cord-262786-otxpc46a	14	4	,	,	,
cord-262786-otxpc46a	14	5	the	the	DT
cord-262786-otxpc46a	14	6	outbreak	outbreak	NN
cord-262786-otxpc46a	14	7	of	of	IN
cord-262786-otxpc46a	14	8	novel	novel	JJ
cord-262786-otxpc46a	14	9	coronavirus	coronavirus	NN
cord-262786-otxpc46a	14	10	disease	disease	NN
cord-262786-otxpc46a	14	11	2019	2019	CD
cord-262786-otxpc46a	14	12	(	(	-LRB-
cord-262786-otxpc46a	14	13	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	14	14	)	)	-RRB-
cord-262786-otxpc46a	14	15	emerged	emerge	VBD
cord-262786-otxpc46a	14	16	in	in	IN
cord-262786-otxpc46a	14	17	Wuhan	Wuhan	NNP
cord-262786-otxpc46a	14	18	,	,	,
cord-262786-otxpc46a	14	19	China	China	NNP
cord-262786-otxpc46a	14	20	.	.	.
cord-262786-otxpc46a	15	1	To	to	IN
cord-262786-otxpc46a	15	2	date	date	NN
cord-262786-otxpc46a	15	3	,	,	,
cord-262786-otxpc46a	15	4	the	the	DT
cord-262786-otxpc46a	15	5	outbreak	outbreak	NN
cord-262786-otxpc46a	15	6	has	have	VBZ
cord-262786-otxpc46a	15	7	turned	turn	VBN
cord-262786-otxpc46a	15	8	into	into	IN
cord-262786-otxpc46a	15	9	a	a	DT
cord-262786-otxpc46a	15	10	pandemic	pandemic	NN
cord-262786-otxpc46a	15	11	,	,	,
cord-262786-otxpc46a	15	12	infecting	infect	VBG
cord-262786-otxpc46a	15	13	millions	million	NNS
cord-262786-otxpc46a	15	14	of	of	IN
cord-262786-otxpc46a	15	15	people	people	NNS
cord-262786-otxpc46a	15	16	globally	globally	RB
cord-262786-otxpc46a	15	17	[	[	-LRB-
cord-262786-otxpc46a	15	18	1	1	CD
cord-262786-otxpc46a	15	19	]	]	-RRB-
cord-262786-otxpc46a	15	20	.	.	.
cord-262786-otxpc46a	16	1	Although	although	IN
cord-262786-otxpc46a	16	2	the	the	DT
cord-262786-otxpc46a	16	3	virus	virus	NN
cord-262786-otxpc46a	16	4	,	,	,
cord-262786-otxpc46a	16	5	also	also	RB
cord-262786-otxpc46a	16	6	known	know	VBN
cord-262786-otxpc46a	16	7	as	as	IN
cord-262786-otxpc46a	16	8	severe	severe	JJ
cord-262786-otxpc46a	16	9	acute	acute	JJ
cord-262786-otxpc46a	16	10	respiratory	respiratory	JJ
cord-262786-otxpc46a	16	11	syndrome	syndrome	NN
cord-262786-otxpc46a	16	12	coronavirus	coronavirus	NN
cord-262786-otxpc46a	16	13	2	2	CD
cord-262786-otxpc46a	16	14	(	(	-LRB-
cord-262786-otxpc46a	16	15	SARS	SARS	NNP
cord-262786-otxpc46a	16	16	-	-	HYPH
cord-262786-otxpc46a	16	17	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	16	18	)	)	-RRB-
cord-262786-otxpc46a	16	19	,	,	,
cord-262786-otxpc46a	16	20	mainly	mainly	RB
cord-262786-otxpc46a	16	21	manifests	manifest	VBZ
cord-262786-otxpc46a	16	22	as	as	IN
cord-262786-otxpc46a	16	23	an	an	DT
cord-262786-otxpc46a	16	24	acute	acute	JJ
cord-262786-otxpc46a	16	25	respiratory	respiratory	JJ
cord-262786-otxpc46a	16	26	infection	infection	NN
cord-262786-otxpc46a	16	27	[	[	-LRB-
cord-262786-otxpc46a	16	28	2	2	CD
cord-262786-otxpc46a	16	29	]	]	-RRB-
cord-262786-otxpc46a	16	30	,	,	,
cord-262786-otxpc46a	16	31	recent	recent	JJ
cord-262786-otxpc46a	16	32	evidence	evidence	NN
cord-262786-otxpc46a	16	33	suggests	suggest	VBZ
cord-262786-otxpc46a	16	34	that	that	IN
cord-262786-otxpc46a	16	35	36	36	CD
cord-262786-otxpc46a	16	36	%	%	NN
cord-262786-otxpc46a	16	37	of	of	IN
cord-262786-otxpc46a	16	38	affected	affect	VBN
cord-262786-otxpc46a	16	39	patients	patient	NNS
cord-262786-otxpc46a	16	40	exhibit	exhibit	VBP
cord-262786-otxpc46a	16	41	neurological	neurological	JJ
cord-262786-otxpc46a	16	42	sequelae	sequela	NNS
cord-262786-otxpc46a	16	43	[	[	-LRB-
cord-262786-otxpc46a	16	44	3	3	CD
cord-262786-otxpc46a	16	45	]	]	-RRB-
cord-262786-otxpc46a	16	46	.	.	.
cord-262786-otxpc46a	17	1	Neurologic	neurologic	JJ
cord-262786-otxpc46a	17	2	symptoms	symptom	NNS
cord-262786-otxpc46a	17	3	are	be	VBP
cord-262786-otxpc46a	17	4	more	more	RBR
cord-262786-otxpc46a	17	5	common	common	JJ
cord-262786-otxpc46a	17	6	among	among	IN
cord-262786-otxpc46a	17	7	severe	severe	JJ
cord-262786-otxpc46a	17	8	cases	case	NNS
cord-262786-otxpc46a	17	9	of	of	IN
cord-262786-otxpc46a	17	10	the	the	DT
cord-262786-otxpc46a	17	11	disease	disease	NN
cord-262786-otxpc46a	17	12	,	,	,
cord-262786-otxpc46a	17	13	regarding	regard	VBG
cord-262786-otxpc46a	17	14	that	that	IN
cord-262786-otxpc46a	17	15	84	84	CD
cord-262786-otxpc46a	17	16	%	%	NN
cord-262786-otxpc46a	17	17	of	of	IN
cord-262786-otxpc46a	17	18	the	the	DT
cord-262786-otxpc46a	17	19	intensive	intensive	JJ
cord-262786-otxpc46a	17	20	care	care	NN
cord-262786-otxpc46a	17	21	unit	unit	NN
cord-262786-otxpc46a	17	22	(	(	-LRB-
cord-262786-otxpc46a	17	23	ICU)-admitted	ICU)-admitted	NNP
cord-262786-otxpc46a	17	24	SARS	SARS	NNP
cord-262786-otxpc46a	17	25	-	-	HYPH
cord-262786-otxpc46a	17	26	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	17	27	patients	patient	NNS
cord-262786-otxpc46a	17	28	exhibited	exhibit	VBD
cord-262786-otxpc46a	17	29	at	at	IN
cord-262786-otxpc46a	17	30	least	least	RBS
cord-262786-otxpc46a	17	31	one	one	CD
cord-262786-otxpc46a	17	32	neurologic	neurologic	JJ
cord-262786-otxpc46a	17	33	symptom	symptom	NN
cord-262786-otxpc46a	17	34	[	[	-LRB-
cord-262786-otxpc46a	17	35	4	4	CD
cord-262786-otxpc46a	17	36	]	]	-RRB-
cord-262786-otxpc46a	17	37	.	.	.
cord-262786-otxpc46a	18	1	In	in	IN
cord-262786-otxpc46a	18	2	line	line	NN
cord-262786-otxpc46a	18	3	with	with	IN
cord-262786-otxpc46a	18	4	these	these	DT
cord-262786-otxpc46a	18	5	,	,	,
cord-262786-otxpc46a	18	6	brain	brain	NN
cord-262786-otxpc46a	18	7	magnetic	magnetic	JJ
cord-262786-otxpc46a	18	8	resonance	resonance	NN
cord-262786-otxpc46a	18	9	imaging	imaging	NN
cord-262786-otxpc46a	18	10	(	(	-LRB-
cord-262786-otxpc46a	18	11	MRI	MRI	NNP
cord-262786-otxpc46a	18	12	)	)	-RRB-
cord-262786-otxpc46a	18	13	investigations	investigation	NNS
cord-262786-otxpc46a	18	14	in	in	IN
cord-262786-otxpc46a	18	15	SARS	SARS	NNP
cord-262786-otxpc46a	18	16	-	-	HYPH
cord-262786-otxpc46a	18	17	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	18	18	patients	patient	NNS
cord-262786-otxpc46a	18	19	show	show	VBP
cord-262786-otxpc46a	18	20	multifocal	multifocal	JJ
cord-262786-otxpc46a	18	21	hyperintense	hyperintense	NNP
cord-262786-otxpc46a	18	22	white	white	NNP
cord-262786-otxpc46a	18	23	matter	matter	NN
cord-262786-otxpc46a	18	24	lesions	lesion	NNS
cord-262786-otxpc46a	18	25	and	and	CC
cord-262786-otxpc46a	18	26	cortical	cortical	JJ
cord-262786-otxpc46a	18	27	signal	signal	NN
cord-262786-otxpc46a	18	28	abnormalities	abnormality	NNS
cord-262786-otxpc46a	18	29	(	(	-LRB-
cord-262786-otxpc46a	18	30	particularly	particularly	RB
cord-262786-otxpc46a	18	31	in	in	IN
cord-262786-otxpc46a	18	32	the	the	DT
cord-262786-otxpc46a	18	33	medial	medial	JJ
cord-262786-otxpc46a	18	34	temporal	temporal	JJ
cord-262786-otxpc46a	18	35	lobe	lobe	NN
cord-262786-otxpc46a	18	36	)	)	-RRB-
cord-262786-otxpc46a	18	37	on	on	IN
cord-262786-otxpc46a	18	38	fluid	fluid	RB
cord-262786-otxpc46a	18	39	-	-	HYPH
cord-262786-otxpc46a	18	40	attenuated	attenuated	JJ
cord-262786-otxpc46a	18	41	inversion	inversion	NN
cord-262786-otxpc46a	18	42	recovery	recovery	NN
cord-262786-otxpc46a	18	43	(	(	-LRB-
cord-262786-otxpc46a	18	44	FLAIR	FLAIR	NNP
cord-262786-otxpc46a	18	45	)	)	-RRB-
cord-262786-otxpc46a	18	46	,	,	,
cord-262786-otxpc46a	18	47	along	along	IN
cord-262786-otxpc46a	18	48	with	with	IN
cord-262786-otxpc46a	18	49	intracerebral	intracerebral	JJ
cord-262786-otxpc46a	18	50	hemorrhagic	hemorrhagic	JJ
cord-262786-otxpc46a	18	51	and	and	CC
cord-262786-otxpc46a	18	52	microhemorrhagic	microhemorrhagic	JJ
cord-262786-otxpc46a	18	53	lesions	lesion	NNS
cord-262786-otxpc46a	18	54	,	,	,
cord-262786-otxpc46a	18	55	a	a	DT
cord-262786-otxpc46a	18	56	n	n	NN
cord-262786-otxpc46a	18	57	d	d	NN
cord-262786-otxpc46a	18	58	l	l	NN
cord-262786-otxpc46a	18	59	e	e	NN
cord-262786-otxpc46a	18	60	p	p	NN
cord-262786-otxpc46a	18	61	t	t	NN
cord-262786-otxpc46a	18	62	o	o	NN
cord-262786-otxpc46a	19	1	m	m	LS
cord-262786-otxpc46a	20	1	e	e	LS
cord-262786-otxpc46a	20	2	n	n	NN
cord-262786-otxpc46a	21	1	i	i	PRP
cord-262786-otxpc46a	21	2	n	n	CC
cord-262786-otxpc46a	21	3	g	g	NN
cord-262786-otxpc46a	22	1	e	e	LS
cord-262786-otxpc46a	22	2	a	a	DT
cord-262786-otxpc46a	23	1	l	l	NNP
cord-262786-otxpc46a	23	2	e	e	NNP
cord-262786-otxpc46a	23	3	n	n	CC
cord-262786-otxpc46a	23	4	h	h	NNP
cord-262786-otxpc46a	23	5	a	a	NNP
cord-262786-otxpc46a	23	6	n	n	NN
cord-262786-otxpc46a	23	7	c	c	NN
cord-262786-otxpc46a	23	8	e	e	NN
cord-262786-otxpc46a	23	9	m	m	NN
cord-262786-otxpc46a	23	10	e	e	NN
cord-262786-otxpc46a	23	11	n	n	NN
cord-262786-otxpc46a	23	12	t	t	NNP
cord-262786-otxpc46a	23	13	[	[	-LRB-
cord-262786-otxpc46a	23	14	5	5	CD
cord-262786-otxpc46a	23	15	,	,	,
cord-262786-otxpc46a	23	16	6	6	CD
cord-262786-otxpc46a	23	17	]	]	-RRB-
cord-262786-otxpc46a	23	18	.	.	.
cord-262786-otxpc46a	24	1	Electroencephalogram	Electroencephalogram	NNP
cord-262786-otxpc46a	24	2	(	(	-LRB-
cord-262786-otxpc46a	24	3	EEG	EEG	NNP
cord-262786-otxpc46a	24	4	)	)	-RRB-
cord-262786-otxpc46a	24	5	studies	study	NNS
cord-262786-otxpc46a	24	6	demonstrate	demonstrate	VBP
cord-262786-otxpc46a	24	7	high	high	JJ
cord-262786-otxpc46a	24	8	amplitude	amplitude	NN
cord-262786-otxpc46a	24	9	monomorphic	monomorphic	JJ
cord-262786-otxpc46a	24	10	delta	delta	NN
cord-262786-otxpc46a	24	11	waves	wave	NNS
cord-262786-otxpc46a	24	12	,	,	,
cord-262786-otxpc46a	24	13	indicating	indicate	VBG
cord-262786-otxpc46a	24	14	the	the	DT
cord-262786-otxpc46a	24	15	central	central	JJ
cord-262786-otxpc46a	24	16	nervous	nervous	JJ
cord-262786-otxpc46a	24	17	system	system	NN
cord-262786-otxpc46a	24	18	(	(	-LRB-
cord-262786-otxpc46a	24	19	CNS	CNS	NNP
cord-262786-otxpc46a	24	20	)	)	-RRB-
cord-262786-otxpc46a	24	21	involvement	involvement	NN
cord-262786-otxpc46a	24	22	in	in	IN
cord-262786-otxpc46a	24	23	SARS	SARS	NNP
cord-262786-otxpc46a	24	24	-	-	HYPH
cord-262786-otxpc46a	24	25	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	24	26	patients	patient	NNS
cord-262786-otxpc46a	24	27	[	[	-LRB-
cord-262786-otxpc46a	24	28	7	7	CD
cord-262786-otxpc46a	24	29	]	]	-RRB-
cord-262786-otxpc46a	24	30	.	.	.
cord-262786-otxpc46a	25	1	Also	also	RB
cord-262786-otxpc46a	25	2	,	,	,
cord-262786-otxpc46a	25	3	functional	functional	JJ
cord-262786-otxpc46a	25	4	magnetic	magnetic	JJ
cord-262786-otxpc46a	25	5	resonance	resonance	NN
cord-262786-otxpc46a	25	6	imaging	imaging	NN
cord-262786-otxpc46a	25	7	(	(	-LRB-
cord-262786-otxpc46a	25	8	fMRI	fMRI	NNP
cord-262786-otxpc46a	25	9	)	)	-RRB-
cord-262786-otxpc46a	25	10	is	be	VBZ
cord-262786-otxpc46a	25	11	recently	recently	RB
cord-262786-otxpc46a	25	12	proposed	propose	VBN
cord-262786-otxpc46a	25	13	as	as	IN
cord-262786-otxpc46a	25	14	an	an	DT
cord-262786-otxpc46a	25	15	independent	independent	JJ
cord-262786-otxpc46a	25	16	predictor	predictor	NN
cord-262786-otxpc46a	25	17	of	of	IN
cord-262786-otxpc46a	25	18	neurologic	neurologic	JJ
cord-262786-otxpc46a	25	19	outcomes	outcome	NNS
cord-262786-otxpc46a	25	20	[	[	-LRB-
cord-262786-otxpc46a	25	21	8	8	CD
cord-262786-otxpc46a	25	22	]	]	-RRB-
cord-262786-otxpc46a	25	23	.	.	.
cord-262786-otxpc46a	26	1	SARS	SARS	NNP
cord-262786-otxpc46a	26	2	-	-	HYPH
cord-262786-otxpc46a	26	3	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	26	4	patients	patient	NNS
cord-262786-otxpc46a	26	5	present	present	JJ
cord-262786-otxpc46a	26	6	with	with	IN
cord-262786-otxpc46a	26	7	elevated	elevated	JJ
cord-262786-otxpc46a	26	8	plasma	plasma	NN
cord-262786-otxpc46a	26	9	levels	level	NNS
cord-262786-otxpc46a	26	10	of	of	IN
cord-262786-otxpc46a	26	11	neurofilament	neurofilament	NNP
cord-262786-otxpc46a	26	12	light	light	NNP
cord-262786-otxpc46a	26	13	chain	chain	NN
cord-262786-otxpc46a	26	14	protein	protein	NN
cord-262786-otxpc46a	26	15	(	(	-LRB-
cord-262786-otxpc46a	26	16	NfL	nfl	NN
cord-262786-otxpc46a	26	17	)	)	-RRB-
cord-262786-otxpc46a	26	18	and	and	CC
cord-262786-otxpc46a	26	19	glial	glial	JJ
cord-262786-otxpc46a	26	20	fibrillary	fibrillary	JJ
cord-262786-otxpc46a	26	21	acidic	acidic	JJ
cord-262786-otxpc46a	26	22	protein	protein	NN
cord-262786-otxpc46a	26	23	(	(	-LRB-
cord-262786-otxpc46a	26	24	GFAP	GFAP	NNP
cord-262786-otxpc46a	26	25	)	)	-RRB-
cord-262786-otxpc46a	26	26	,	,	,
cord-262786-otxpc46a	26	27	which	which	WDT
cord-262786-otxpc46a	26	28	are	be	VBP
cord-262786-otxpc46a	26	29	known	know	VBN
cord-262786-otxpc46a	26	30	as	as	IN
cord-262786-otxpc46a	26	31	biochemical	biochemical	JJ
cord-262786-otxpc46a	26	32	indicators	indicator	NNS
cord-262786-otxpc46a	26	33	of	of	IN
cord-262786-otxpc46a	26	34	neuronal	neuronal	JJ
cord-262786-otxpc46a	26	35	injury	injury	NN
cord-262786-otxpc46a	26	36	and	and	CC
cord-262786-otxpc46a	26	37	glial	glial	JJ
cord-262786-otxpc46a	26	38	activation	activation	NN
cord-262786-otxpc46a	26	39	,	,	,
cord-262786-otxpc46a	26	40	respectively	respectively	RB
cord-262786-otxpc46a	26	41	[	[	-LRB-
cord-262786-otxpc46a	26	42	9	9	CD
cord-262786-otxpc46a	26	43	]	]	-RRB-
cord-262786-otxpc46a	26	44	.	.	.
cord-262786-otxpc46a	27	1	Also	also	RB
cord-262786-otxpc46a	27	2	,	,	,
cord-262786-otxpc46a	27	3	postmortem	postmortem	JJ
cord-262786-otxpc46a	27	4	brain	brain	NN
cord-262786-otxpc46a	27	5	autopsies	autopsy	NNS
cord-262786-otxpc46a	27	6	demonstrate	demonstrate	VBP
cord-262786-otxpc46a	27	7	virus	virus	NN
cord-262786-otxpc46a	27	8	invasion	invasion	NN
cord-262786-otxpc46a	27	9	to	to	IN
cord-262786-otxpc46a	27	10	different	different	JJ
cord-262786-otxpc46a	27	11	brain	brain	NN
cord-262786-otxpc46a	27	12	regions	region	NNS
cord-262786-otxpc46a	27	13	,	,	,
cord-262786-otxpc46a	27	14	including	include	VBG
cord-262786-otxpc46a	27	15	the	the	DT
cord-262786-otxpc46a	27	16	hypothalamus	hypothalamus	NN
cord-262786-otxpc46a	27	17	and	and	CC
cord-262786-otxpc46a	27	18	olfactory	olfactory	JJ
cord-262786-otxpc46a	27	19	bulb	bulb	NN
cord-262786-otxpc46a	27	20	,	,	,
cord-262786-otxpc46a	27	21	accompanied	accompany	VBN
cord-262786-otxpc46a	27	22	by	by	IN
cord-262786-otxpc46a	27	23	neural	neural	JJ
cord-262786-otxpc46a	27	24	death	death	NN
cord-262786-otxpc46a	27	25	and	and	CC
cord-262786-otxpc46a	27	26	demyelination	demyelination	NN
cord-262786-otxpc46a	27	27	[	[	-LRB-
cord-262786-otxpc46a	27	28	10	10	CD
cord-262786-otxpc46a	27	29	,	,	,
cord-262786-otxpc46a	27	30	11	11	CD
cord-262786-otxpc46a	27	31	]	]	-RRB-
cord-262786-otxpc46a	27	32	.	.	.
cord-262786-otxpc46a	28	1	Several	several	JJ
cord-262786-otxpc46a	28	2	pathogenic	pathogenic	JJ
cord-262786-otxpc46a	28	3	mechanisms	mechanism	NNS
cord-262786-otxpc46a	28	4	have	have	VBP
cord-262786-otxpc46a	28	5	been	be	VBN
cord-262786-otxpc46a	28	6	proposed	propose	VBN
cord-262786-otxpc46a	28	7	for	for	IN
cord-262786-otxpc46a	28	8	the	the	DT
cord-262786-otxpc46a	28	9	neurological	neurological	JJ
cord-262786-otxpc46a	28	10	deficit	deficit	NN
cord-262786-otxpc46a	28	11	in	in	IN
cord-262786-otxpc46a	28	12	SARS	SARS	NNP
cord-262786-otxpc46a	28	13	-	-	HYPH
cord-262786-otxpc46a	28	14	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	28	15	:	:	:
cord-262786-otxpc46a	28	16	indirect	indirect	JJ
cord-262786-otxpc46a	28	17	CNS	CNS	NNP
cord-262786-otxpc46a	28	18	involvement	involvement	NN
cord-262786-otxpc46a	28	19	through	through	IN
cord-262786-otxpc46a	28	20	systemic	systemic	JJ
cord-262786-otxpc46a	28	21	inflammation	inflammation	NN
cord-262786-otxpc46a	28	22	,	,	,
cord-262786-otxpc46a	28	23	direct	direct	JJ
cord-262786-otxpc46a	28	24	invasion	invasion	NN
cord-262786-otxpc46a	28	25	of	of	IN
cord-262786-otxpc46a	28	26	the	the	DT
cord-262786-otxpc46a	28	27	virus	virus	NN
cord-262786-otxpc46a	28	28	into	into	IN
cord-262786-otxpc46a	28	29	the	the	DT
cord-262786-otxpc46a	28	30	CNS	CNS	NNP
cord-262786-otxpc46a	28	31	,	,	,
cord-262786-otxpc46a	28	32	multi	multi	JJ
cord-262786-otxpc46a	28	33	-	-	JJ
cord-262786-otxpc46a	28	34	organ	organ	JJ
cord-262786-otxpc46a	28	35	failure	failure	NN
cord-262786-otxpc46a	28	36	,	,	,
cord-262786-otxpc46a	28	37	hypoxia	hypoxia	NN
cord-262786-otxpc46a	28	38	,	,	,
cord-262786-otxpc46a	28	39	sepsis	sepsis	NN
cord-262786-otxpc46a	28	40	,	,	,
cord-262786-otxpc46a	28	41	etc	etc	FW
cord-262786-otxpc46a	28	42	.	.	.
cord-262786-otxpc46a	29	1	[	[	-LRB-
cord-262786-otxpc46a	29	2	12	12	CD
cord-262786-otxpc46a	29	3	,	,	,
cord-262786-otxpc46a	29	4	13	13	CD
cord-262786-otxpc46a	29	5	]	]	-RRB-
cord-262786-otxpc46a	29	6	.	.	.
cord-262786-otxpc46a	30	1	In	in	IN
cord-262786-otxpc46a	30	2	this	this	DT
cord-262786-otxpc46a	30	3	article	article	NN
cord-262786-otxpc46a	30	4	,	,	,
cord-262786-otxpc46a	30	5	we	-PRON-	PRP
cord-262786-otxpc46a	30	6	aim	aim	VBP
cord-262786-otxpc46a	30	7	to	to	TO
cord-262786-otxpc46a	30	8	revisit	revisit	VB
cord-262786-otxpc46a	30	9	the	the	DT
cord-262786-otxpc46a	30	10	possible	possible	JJ
cord-262786-otxpc46a	30	11	pathomechanisms	pathomechanism	NNS
cord-262786-otxpc46a	30	12	that	that	WDT
cord-262786-otxpc46a	30	13	may	may	MD
cord-262786-otxpc46a	30	14	contribute	contribute	VB
cord-262786-otxpc46a	30	15	to	to	IN
cord-262786-otxpc46a	30	16	development	development	NN
cord-262786-otxpc46a	30	17	of	of	IN
cord-262786-otxpc46a	30	18	neurologic	neurologic	JJ
cord-262786-otxpc46a	30	19	complications	complication	NNS
cord-262786-otxpc46a	30	20	in	in	IN
cord-262786-otxpc46a	30	21	patients	patient	NNS
cord-262786-otxpc46a	30	22	afflicted	afflict	VBN
cord-262786-otxpc46a	30	23	with	with	IN
cord-262786-otxpc46a	30	24	this	this	DT
cord-262786-otxpc46a	30	25	virus	virus	NN
cord-262786-otxpc46a	30	26	with	with	IN
cord-262786-otxpc46a	30	27	a	a	DT
cord-262786-otxpc46a	30	28	substantial	substantial	JJ
cord-262786-otxpc46a	30	29	focus	focus	NN
cord-262786-otxpc46a	30	30	on	on	IN
cord-262786-otxpc46a	30	31	immunological	immunological	JJ
cord-262786-otxpc46a	30	32	pathways	pathway	NNS
cord-262786-otxpc46a	30	33	.	.	.
cord-262786-otxpc46a	31	1	angiotensin	angiotensin	NN
cord-262786-otxpc46a	31	2	-	-	HYPH
cord-262786-otxpc46a	31	3	converting	convert	VBG
cord-262786-otxpc46a	31	4	enzyme	enzyme	NN
cord-262786-otxpc46a	31	5	2	2	CD
cord-262786-otxpc46a	31	6	(	(	-LRB-
cord-262786-otxpc46a	31	7	ACE-2	ACE-2	NNP
cord-262786-otxpc46a	31	8	)	)	-RRB-
cord-262786-otxpc46a	31	9	[	[	-LRB-
cord-262786-otxpc46a	31	10	19	19	CD
cord-262786-otxpc46a	31	11	]	]	-RRB-
cord-262786-otxpc46a	31	12	.	.	.
cord-262786-otxpc46a	32	1	Further	further	JJ
cord-262786-otxpc46a	32	2	investigations	investigation	NNS
cord-262786-otxpc46a	32	3	in	in	IN
cord-262786-otxpc46a	32	4	rodents	rodent	NNS
cord-262786-otxpc46a	32	5	show	show	VBP
cord-262786-otxpc46a	32	6	that	that	IN
cord-262786-otxpc46a	32	7	ACE-2	ACE-2	NNP
cord-262786-otxpc46a	32	8	is	be	VBZ
cord-262786-otxpc46a	32	9	expressed	express	VBN
cord-262786-otxpc46a	32	10	in	in	IN
cord-262786-otxpc46a	32	11	brain	brain	NN
cord-262786-otxpc46a	32	12	regions	region	NNS
cord-262786-otxpc46a	32	13	like	like	IN
cord-262786-otxpc46a	32	14	cortex	cortex	NN
cord-262786-otxpc46a	32	15	and	and	CC
cord-262786-otxpc46a	32	16	raphe	raphe	NN
cord-262786-otxpc46a	32	17	and	and	CC
cord-262786-otxpc46a	32	18	brainstem	brainstem	NN
cord-262786-otxpc46a	32	19	,	,	,
cord-262786-otxpc46a	32	20	predominantly	predominantly	RB
cord-262786-otxpc46a	32	21	in	in	IN
cord-262786-otxpc46a	32	22	neurons	neuron	NNS
cord-262786-otxpc46a	32	23	[	[	-LRB-
cord-262786-otxpc46a	32	24	19	19	CD
cord-262786-otxpc46a	32	25	]	]	-RRB-
cord-262786-otxpc46a	32	26	.	.	.
cord-262786-otxpc46a	33	1	Also	also	RB
cord-262786-otxpc46a	33	2	,	,	,
cord-262786-otxpc46a	33	3	spatial	spatial	JJ
cord-262786-otxpc46a	33	4	distribution	distribution	NN
cord-262786-otxpc46a	33	5	analysis	analysis	NN
cord-262786-otxpc46a	33	6	reveals	reveal	VBZ
cord-262786-otxpc46a	33	7	that	that	IN
cord-262786-otxpc46a	33	8	ACE-2	ACE-2	NNP
cord-262786-otxpc46a	33	9	is	be	VBZ
cord-262786-otxpc46a	33	10	highly	highly	RB
cord-262786-otxpc46a	33	11	expressed	express	VBN
cord-262786-otxpc46a	33	12	by	by	IN
cord-262786-otxpc46a	33	13	neurons	neuron	NNS
cord-262786-otxpc46a	33	14	and	and	CC
cord-262786-otxpc46a	33	15	glial	glial	JJ
cord-262786-otxpc46a	33	16	cells	cell	NNS
cord-262786-otxpc46a	33	17	in	in	IN
cord-262786-otxpc46a	33	18	different	different	JJ
cord-262786-otxpc46a	33	19	human	human	JJ
cord-262786-otxpc46a	33	20	brain	brain	NN
cord-262786-otxpc46a	33	21	regions	region	NNS
cord-262786-otxpc46a	33	22	,	,	,
cord-262786-otxpc46a	33	23	including	include	VBG
cord-262786-otxpc46a	33	24	middle	middle	JJ
cord-262786-otxpc46a	33	25	temporal	temporal	JJ
cord-262786-otxpc46a	33	26	gyrus	gyrus	NNP
cord-262786-otxpc46a	33	27	,	,	,
cord-262786-otxpc46a	33	28	cingulate	cingulate	NNP
cord-262786-otxpc46a	33	29	gyrus	gyrus	NNP
cord-262786-otxpc46a	33	30	,	,	,
cord-262786-otxpc46a	33	31	substantia	substantia	NNP
cord-262786-otxpc46a	33	32	nigra	nigra	NN
cord-262786-otxpc46a	33	33	,	,	,
cord-262786-otxpc46a	33	34	choroid	choroid	NN
cord-262786-otxpc46a	33	35	plexus	plexus	NN
cord-262786-otxpc46a	33	36	,	,	,
cord-262786-otxpc46a	33	37	and	and	CC
cord-262786-otxpc46a	33	38	,	,	,
cord-262786-otxpc46a	33	39	to	to	IN
cord-262786-otxpc46a	33	40	a	a	DT
cord-262786-otxpc46a	33	41	lesser	less	JJR
cord-262786-otxpc46a	33	42	extent	extent	NN
cord-262786-otxpc46a	33	43	,	,	,
cord-262786-otxpc46a	33	44	hippocampus	hippocampus	NN
cord-262786-otxpc46a	33	45	[	[	-LRB-
cord-262786-otxpc46a	33	46	20	20	CD
cord-262786-otxpc46a	33	47	]	]	-RRB-
cord-262786-otxpc46a	33	48	.	.	.
cord-262786-otxpc46a	34	1	A	a	DT
cord-262786-otxpc46a	34	2	C	c	NN
cord-262786-otxpc46a	34	3	E	e	NN
cord-262786-otxpc46a	34	4	-2	-2	NN
cord-262786-otxpc46a	35	1	i	i	PRP
cord-262786-otxpc46a	35	2	s	s	VBZ
cord-262786-otxpc46a	35	3	a	a	DT
cord-262786-otxpc46a	35	4	t	t	NN
cord-262786-otxpc46a	35	5	y	y	NN
cord-262786-otxpc46a	35	6	p	p	NN
cord-262786-otxpc46a	35	7	e	e	NN
cord-262786-otxpc46a	35	8	I	i	NN
cord-262786-otxpc46a	36	1	t	t	NNP
cord-262786-otxpc46a	36	2	r	r	NNP
cord-262786-otxpc46a	37	1	a	a	DT
cord-262786-otxpc46a	37	2	n	n	NNP
cord-262786-otxpc46a	37	3	s	s	NNP
cord-262786-otxpc46a	37	4	m	m	NN
cord-262786-otxpc46a	37	5	e	e	NN
cord-262786-otxpc46a	37	6	m	m	NN
cord-262786-otxpc46a	37	7	b	b	NNP
cord-262786-otxpc46a	37	8	r	r	NNP
cord-262786-otxpc46a	37	9	a	a	NN
cord-262786-otxpc46a	37	10	n	n	NN
cord-262786-otxpc46a	37	11	e	e	DT
cord-262786-otxpc46a	37	12	metallocarboxypeptidase	metallocarboxypeptidase	NN
cord-262786-otxpc46a	37	13	that	that	WDT
cord-262786-otxpc46a	37	14	acts	act	VBZ
cord-262786-otxpc46a	37	15	as	as	IN
cord-262786-otxpc46a	37	16	a	a	DT
cord-262786-otxpc46a	37	17	receptor	receptor	NN
cord-262786-otxpc46a	37	18	for	for	IN
cord-262786-otxpc46a	37	19	SARS	SARS	NNP
cord-262786-otxpc46a	37	20	-	-	HYPH
cord-262786-otxpc46a	37	21	CoV	CoV	NNP
cord-262786-otxpc46a	37	22	as	as	RB
cord-262786-otxpc46a	37	23	well	well	RB
cord-262786-otxpc46a	37	24	as	as	IN
cord-262786-otxpc46a	37	25	SARS	SARS	NNP
cord-262786-otxpc46a	37	26	-	-	HYPH
cord-262786-otxpc46a	37	27	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	37	28	[	[	-LRB-
cord-262786-otxpc46a	37	29	21	21	CD
cord-262786-otxpc46a	37	30	]	]	-RRB-
cord-262786-otxpc46a	37	31	.	.	.
cord-262786-otxpc46a	38	1	Binding	bind	VBG
cord-262786-otxpc46a	38	2	of	of	IN
cord-262786-otxpc46a	38	3	viral	viral	JJ
cord-262786-otxpc46a	38	4	spike	spike	NN
cord-262786-otxpc46a	38	5	(	(	-LRB-
cord-262786-otxpc46a	38	6	S	s	NN
cord-262786-otxpc46a	38	7	)	)	-RRB-
cord-262786-otxpc46a	38	8	protein	protein	NN
cord-262786-otxpc46a	38	9	to	to	IN
cord-262786-otxpc46a	38	10	ACE-2	ACE-2	NNP
cord-262786-otxpc46a	38	11	receptors	receptor	NNS
cord-262786-otxpc46a	38	12	accompanied	accompany	VBN
cord-262786-otxpc46a	38	13	by	by	IN
cord-262786-otxpc46a	38	14	proteolytic	proteolytic	JJ
cord-262786-otxpc46a	38	15	cleavage	cleavage	NN
cord-262786-otxpc46a	38	16	of	of	IN
cord-262786-otxpc46a	38	17	viral	viral	JJ
cord-262786-otxpc46a	38	18	spike	spike	NN
cord-262786-otxpc46a	38	19	protein	protein	NN
cord-262786-otxpc46a	38	20	mediated	mediate	VBN
cord-262786-otxpc46a	38	21	by	by	IN
cord-262786-otxpc46a	38	22	transmembrane	transmembrane	NN
cord-262786-otxpc46a	38	23	serine	serine	NN
cord-262786-otxpc46a	38	24	protease	protease	NN
cord-262786-otxpc46a	38	25	2	2	CD
cord-262786-otxpc46a	38	26	(	(	-LRB-
cord-262786-otxpc46a	38	27	TMPRSS2	TMPRSS2	NNP
cord-262786-otxpc46a	38	28	)	)	-RRB-
cord-262786-otxpc46a	38	29	facilitates	facilitate	VBZ
cord-262786-otxpc46a	38	30	cell	cell	NN
cord-262786-otxpc46a	38	31	entry	entry	NN
cord-262786-otxpc46a	38	32	(	(	-LRB-
cord-262786-otxpc46a	38	33	Fig	Fig	NNP
cord-262786-otxpc46a	38	34	.	.	.
cord-262786-otxpc46a	38	35	1	1	CD
cord-262786-otxpc46a	38	36	)	)	-RRB-
cord-262786-otxpc46a	39	1	[	[	-LRB-
cord-262786-otxpc46a	39	2	21	21	CD
cord-262786-otxpc46a	39	3	]	]	-RRB-
cord-262786-otxpc46a	39	4	.	.	.
cord-262786-otxpc46a	40	1	Systemic	systemic	JJ
cord-262786-otxpc46a	40	2	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	40	3	response	response	NN
cord-262786-otxpc46a	40	4	syndrome	syndrome	NN
cord-262786-otxpc46a	40	5	(	(	-LRB-
cord-262786-otxpc46a	40	6	SIRS	SIRS	NNP
cord-262786-otxpc46a	40	7	)	)	-RRB-
cord-262786-otxpc46a	40	8	is	be	VBZ
cord-262786-otxpc46a	40	9	defined	define	VBN
cord-262786-otxpc46a	40	10	as	as	IN
cord-262786-otxpc46a	40	11	excessive	excessive	JJ
cord-262786-otxpc46a	40	12	host	host	NN
cord-262786-otxpc46a	40	13	immune	immune	JJ
cord-262786-otxpc46a	40	14	response	response	NN
cord-262786-otxpc46a	40	15	against	against	IN
cord-262786-otxpc46a	40	16	noxious	noxious	JJ
cord-262786-otxpc46a	40	17	stimuli	stimulus	NNS
cord-262786-otxpc46a	40	18	(	(	-LRB-
cord-262786-otxpc46a	40	19	e.g.	e.g.	RB
cord-262786-otxpc46a	40	20	,	,	,
cord-262786-otxpc46a	40	21	viral	viral	JJ
cord-262786-otxpc46a	40	22	infection	infection	NN
cord-262786-otxpc46a	40	23	)	)	-RRB-
cord-262786-otxpc46a	40	24	,	,	,
cord-262786-otxpc46a	40	25	through	through	IN
cord-262786-otxpc46a	40	26	which	which	WDT
cord-262786-otxpc46a	40	27	the	the	DT
cord-262786-otxpc46a	40	28	primary	primary	JJ
cord-262786-otxpc46a	40	29	protective	protective	JJ
cord-262786-otxpc46a	40	30	role	role	NN
cord-262786-otxpc46a	40	31	of	of	IN
cord-262786-otxpc46a	40	32	cytokine	cytokine	NN
cord-262786-otxpc46a	40	33	release	release	NN
cord-262786-otxpc46a	40	34	turns	turn	VBZ
cord-262786-otxpc46a	40	35	into	into	IN
cord-262786-otxpc46a	40	36	a	a	DT
cord-262786-otxpc46a	40	37	detrimental	detrimental	JJ
cord-262786-otxpc46a	40	38	response	response	NN
cord-262786-otxpc46a	40	39	against	against	IN
cord-262786-otxpc46a	40	40	host	host	NN
cord-262786-otxpc46a	40	41	tissues	tissue	NNS
cord-262786-otxpc46a	40	42	,	,	,
cord-262786-otxpc46a	40	43	leading	lead	VBG
cord-262786-otxpc46a	40	44	to	to	IN
cord-262786-otxpc46a	40	45	impaired	impaired	JJ
cord-262786-otxpc46a	40	46	integrity	integrity	NN
cord-262786-otxpc46a	40	47	of	of	IN
cord-262786-otxpc46a	40	48	capillary	capillary	JJ
cord-262786-otxpc46a	40	49	walls	wall	NNS
cord-262786-otxpc46a	40	50	and	and	CC
cord-262786-otxpc46a	40	51	end	end	NN
cord-262786-otxpc46a	40	52	-	-	HYPH
cord-262786-otxpc46a	40	53	organ	organ	NN
cord-262786-otxpc46a	40	54	dysfunction	dysfunction	NN
cord-262786-otxpc46a	40	55	[	[	-LRB-
cord-262786-otxpc46a	40	56	22	22	CD
cord-262786-otxpc46a	40	57	]	]	-RRB-
cord-262786-otxpc46a	40	58	.	.	.
cord-262786-otxpc46a	41	1	SIRS	SIRS	NNP
cord-262786-otxpc46a	41	2	accounts	account	VBZ
cord-262786-otxpc46a	41	3	for	for	IN
cord-262786-otxpc46a	41	4	the	the	DT
cord-262786-otxpc46a	41	5	neurologic	neurologic	JJ
cord-262786-otxpc46a	41	6	sequelae	sequela	NNS
cord-262786-otxpc46a	41	7	found	find	VBN
cord-262786-otxpc46a	41	8	in	in	IN
cord-262786-otxpc46a	41	9	SARS	SARS	NNP
cord-262786-otxpc46a	41	10	-	-	HYPH
cord-262786-otxpc46a	41	11	CoV	CoV	NNP
cord-262786-otxpc46a	41	12	patients	patient	NNS
cord-262786-otxpc46a	41	13	[	[	-LRB-
cord-262786-otxpc46a	41	14	23	23	CD
cord-262786-otxpc46a	41	15	]	]	-RRB-
cord-262786-otxpc46a	41	16	.	.	.
cord-262786-otxpc46a	42	1	SARS	SARS	NNP
cord-262786-otxpc46a	42	2	-	-	HYPH
cord-262786-otxpc46a	42	3	CoV	CoV	NNP
cord-262786-otxpc46a	42	4	infects	infect	VBZ
cord-262786-otxpc46a	42	5	macrophages	macrophage	NNS
cord-262786-otxpc46a	42	6	,	,	,
cord-262786-otxpc46a	42	7	monocytes	monocyte	NNS
cord-262786-otxpc46a	42	8	,	,	,
cord-262786-otxpc46a	42	9	and	and	CC
cord-262786-otxpc46a	42	10	dendritic	dendritic	JJ
cord-262786-otxpc46a	42	11	cells	cell	NNS
cord-262786-otxpc46a	42	12	and	and	CC
cord-262786-otxpc46a	42	13	upregulates	upregulate	VBZ
cord-262786-otxpc46a	42	14	the	the	DT
cord-262786-otxpc46a	42	15	expression	expression	NN
cord-262786-otxpc46a	42	16	of	of	IN
cord-262786-otxpc46a	42	17	proinflammatory	proinflammatory	JJ
cord-262786-otxpc46a	42	18	cytokines	cytokine	NNS
cord-262786-otxpc46a	42	19	(	(	-LRB-
cord-262786-otxpc46a	42	20	e.g.	e.g.	RB
cord-262786-otxpc46a	42	21	,	,	,
cord-262786-otxpc46a	42	22	tumor	tumor	NN
cord-262786-otxpc46a	42	23	necrosis	necrosis	NN
cord-262786-otxpc46a	42	24	factor	factor	NN
cord-262786-otxpc46a	42	25	-	-	HYPH
cord-262786-otxpc46a	42	26	α	α	NN
cord-262786-otxpc46a	42	27	(	(	-LRB-
cord-262786-otxpc46a	42	28	TNF	TNF	NNP
cord-262786-otxpc46a	42	29	-	-	HYPH
cord-262786-otxpc46a	42	30	α	α	NNP
cord-262786-otxpc46a	42	31	)	)	-RRB-
cord-262786-otxpc46a	42	32	,	,	,
cord-262786-otxpc46a	42	33	interleukin-6	interleukin-6	NNP
cord-262786-otxpc46a	42	34	(	(	-LRB-
cord-262786-otxpc46a	42	35	IL-6	IL-6	NNP
cord-262786-otxpc46a	42	36	)	)	-RRB-
cord-262786-otxpc46a	42	37	)	)	-RRB-
cord-262786-otxpc46a	42	38	,	,	,
cord-262786-otxpc46a	42	39	and	and	CC
cord-262786-otxpc46a	42	40	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	42	41	chemokines	chemokine	NNS
cord-262786-otxpc46a	42	42	Fig	fig	NN
cord-262786-otxpc46a	42	43	.	.	.
cord-262786-otxpc46a	43	1	1	1	LS
cord-262786-otxpc46a	44	1	Three	three	CD
cord-262786-otxpc46a	44	2	phases	phase	NNS
cord-262786-otxpc46a	44	3	of	of	IN
cord-262786-otxpc46a	44	4	CNS	CNS	NNP
cord-262786-otxpc46a	44	5	infection	infection	NN
cord-262786-otxpc46a	44	6	by	by	IN
cord-262786-otxpc46a	44	7	SARS	SARS	NNP
cord-262786-otxpc46a	44	8	-	-	HYPH
cord-262786-otxpc46a	44	9	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	44	10	.	.	.
cord-262786-otxpc46a	45	1	First	first	RB
cord-262786-otxpc46a	45	2	,	,	,
cord-262786-otxpc46a	45	3	the	the	DT
cord-262786-otxpc46a	45	4	virus	virus	NN
cord-262786-otxpc46a	45	5	directly	directly	RB
cord-262786-otxpc46a	45	6	invades	invade	VBZ
cord-262786-otxpc46a	45	7	the	the	DT
cord-262786-otxpc46a	45	8	brain	brain	NN
cord-262786-otxpc46a	45	9	through	through	IN
cord-262786-otxpc46a	45	10	vascular	vascular	JJ
cord-262786-otxpc46a	45	11	or	or	CC
cord-262786-otxpc46a	45	12	retrograde	retrograde	JJ
cord-262786-otxpc46a	45	13	axonal	axonal	JJ
cord-262786-otxpc46a	45	14	transport	transport	NN
cord-262786-otxpc46a	45	15	within	within	IN
cord-262786-otxpc46a	45	16	the	the	DT
cord-262786-otxpc46a	45	17	cribriform	cribriform	NNP
cord-262786-otxpc46a	45	18	plate	plate	NN
cord-262786-otxpc46a	45	19	,	,	,
cord-262786-otxpc46a	45	20	and	and	CC
cord-262786-otxpc46a	45	21	thus	thus	RB
cord-262786-otxpc46a	45	22	the	the	DT
cord-262786-otxpc46a	45	23	viral	viral	JJ
cord-262786-otxpc46a	45	24	load	load	NN
cord-262786-otxpc46a	45	25	increases	increase	NNS
cord-262786-otxpc46a	45	26	in	in	IN
cord-262786-otxpc46a	45	27	the	the	DT
cord-262786-otxpc46a	45	28	CSF	CSF	NNP
cord-262786-otxpc46a	45	29	.	.	.
cord-262786-otxpc46a	46	1	Second	second	RB
cord-262786-otxpc46a	46	2	,	,	,
cord-262786-otxpc46a	46	3	the	the	DT
cord-262786-otxpc46a	46	4	virus	virus	NN
cord-262786-otxpc46a	46	5	infects	infect	VBZ
cord-262786-otxpc46a	46	6	,	,	,
cord-262786-otxpc46a	46	7	replicates	replicate	VBZ
cord-262786-otxpc46a	46	8	in	in	IN
cord-262786-otxpc46a	46	9	,	,	,
cord-262786-otxpc46a	46	10	and	and	CC
cord-262786-otxpc46a	46	11	kills	kill	VBZ
cord-262786-otxpc46a	46	12	neural	neural	JJ
cord-262786-otxpc46a	46	13	cells	cell	NNS
cord-262786-otxpc46a	46	14	through	through	IN
cord-262786-otxpc46a	46	15	ACE-2	ACE-2	NNP
cord-262786-otxpc46a	46	16	receptors	receptor	NNS
cord-262786-otxpc46a	46	17	and	and	CC
cord-262786-otxpc46a	46	18	TMPRSS2	TMPRSS2	NNP
cord-262786-otxpc46a	46	19	,	,	,
cord-262786-otxpc46a	46	20	a	a	DT
cord-262786-otxpc46a	46	21	facilitator	facilitator	NN
cord-262786-otxpc46a	46	22	of	of	IN
cord-262786-otxpc46a	46	23	viral	viral	JJ
cord-262786-otxpc46a	46	24	entry	entry	NN
cord-262786-otxpc46a	46	25	.	.	.
cord-262786-otxpc46a	47	1	Finally	finally	RB
cord-262786-otxpc46a	47	2	,	,	,
cord-262786-otxpc46a	47	3	in	in	IN
cord-262786-otxpc46a	47	4	the	the	DT
cord-262786-otxpc46a	47	5	third	third	JJ
cord-262786-otxpc46a	47	6	phase	phase	NN
cord-262786-otxpc46a	47	7	,	,	,
cord-262786-otxpc46a	47	8	the	the	DT
cord-262786-otxpc46a	47	9	immune	immune	NN
cord-262786-otxpc46a	47	10	-	-	HYPH
cord-262786-otxpc46a	47	11	mediated	mediate	VBN
cord-262786-otxpc46a	47	12	response	response	NN
cord-262786-otxpc46a	47	13	against	against	IN
cord-262786-otxpc46a	47	14	the	the	DT
cord-262786-otxpc46a	47	15	virus	virus	NN
cord-262786-otxpc46a	47	16	can	can	MD
cord-262786-otxpc46a	47	17	indirectly	indirectly	RB
cord-262786-otxpc46a	47	18	involve	involve	VB
cord-262786-otxpc46a	47	19	the	the	DT
cord-262786-otxpc46a	47	20	brain	brain	NN
cord-262786-otxpc46a	47	21	,	,	,
cord-262786-otxpc46a	47	22	although	although	IN
cord-262786-otxpc46a	47	23	the	the	DT
cord-262786-otxpc46a	47	24	viral	viral	JJ
cord-262786-otxpc46a	47	25	replication	replication	NN
cord-262786-otxpc46a	47	26	declines	decline	NNS
cord-262786-otxpc46a	47	27	in	in	IN
cord-262786-otxpc46a	47	28	this	this	DT
cord-262786-otxpc46a	47	29	last	last	JJ
cord-262786-otxpc46a	47	30	phase	phase	NN
cord-262786-otxpc46a	47	31	.	.	.
cord-262786-otxpc46a	48	1	CNS	CNS	NNP
cord-262786-otxpc46a	48	2	central	central	JJ
cord-262786-otxpc46a	48	3	nervous	nervous	JJ
cord-262786-otxpc46a	48	4	system	system	NN
cord-262786-otxpc46a	48	5	,	,	,
cord-262786-otxpc46a	48	6	ACE-2	ACE-2	NNP
cord-262786-otxpc46a	48	7	angiotensin	angiotensin	NN
cord-262786-otxpc46a	48	8	-	-	HYPH
cord-262786-otxpc46a	48	9	converting	convert	VBG
cord-262786-otxpc46a	48	10	enzyme	enzyme	NN
cord-262786-otxpc46a	48	11	2	2	CD
cord-262786-otxpc46a	48	12	,	,	,
cord-262786-otxpc46a	48	13	TMPRSS2	TMPRSS2	NNP
cord-262786-otxpc46a	48	14	transmembrane	transmembrane	NN
cord-262786-otxpc46a	48	15	serine	serine	NN
cord-262786-otxpc46a	48	16	protease	protease	NN
cord-262786-otxpc46a	48	17	2	2	CD
cord-262786-otxpc46a	48	18	.	.	.
cord-262786-otxpc46a	49	1	Adopted	adopt	VBN
cord-262786-otxpc46a	49	2	from	from	IN
cord-262786-otxpc46a	49	3	https://www.dpz.eu/de/infothek/wissen/coronaviren.html	https://www.dpz.eu/de/infothek/wissen/coronaviren.html	ADD
cord-262786-otxpc46a	49	4	,	,	,
cord-262786-otxpc46a	49	5	by	by	IN
cord-262786-otxpc46a	49	6	Markus	Markus	NNP
cord-262786-otxpc46a	49	7	Hoffmann	Hoffmann	NNP
cord-262786-otxpc46a	49	8	.	.	.
cord-262786-otxpc46a	50	1	Adopted	adopt	VBN
cord-262786-otxpc46a	50	2	with	with	IN
cord-262786-otxpc46a	50	3	permission	permission	NN
cord-262786-otxpc46a	50	4	(	(	-LRB-
cord-262786-otxpc46a	50	5	C	C	NNP
cord-262786-otxpc46a	50	6	-	-	HYPH
cord-262786-otxpc46a	50	7	C	C	NNP
cord-262786-otxpc46a	50	8	motif	motif	NN
cord-262786-otxpc46a	50	9	chemokine	chemokine	NN
cord-262786-otxpc46a	50	10	ligand	ligand	NN
cord-262786-otxpc46a	50	11	2	2	CD
cord-262786-otxpc46a	50	12	(	(	-LRB-
cord-262786-otxpc46a	50	13	CCL2	CCL2	NNP
cord-262786-otxpc46a	50	14	)	)	-RRB-
cord-262786-otxpc46a	50	15	,	,	,
cord-262786-otxpc46a	50	16	C	C	NNP
cord-262786-otxpc46a	50	17	-	-	HYPH
cord-262786-otxpc46a	50	18	C	C	NNP
cord-262786-otxpc46a	50	19	motif	motif	NN
cord-262786-otxpc46a	50	20	chemokine	chemokine	NN
cord-262786-otxpc46a	50	21	ligand	ligand	NN
cord-262786-otxpc46a	50	22	3	3	CD
cord-262786-otxpc46a	50	23	(	(	-LRB-
cord-262786-otxpc46a	50	24	CCL3	CCL3	NNP
cord-262786-otxpc46a	50	25	)	)	-RRB-
cord-262786-otxpc46a	50	26	,	,	,
cord-262786-otxpc46a	50	27	C	C	NNP
cord-262786-otxpc46a	50	28	-	-	HYPH
cord-262786-otxpc46a	50	29	C	C	NNP
cord-262786-otxpc46a	50	30	motif	motif	NN
cord-262786-otxpc46a	50	31	chemokine	chemokine	NN
cord-262786-otxpc46a	50	32	ligand	ligand	NN
cord-262786-otxpc46a	50	33	5	5	CD
cord-262786-otxpc46a	50	34	(	(	-LRB-
cord-262786-otxpc46a	50	35	CCL5	CCL5	NNP
cord-262786-otxpc46a	50	36	)	)	-RRB-
cord-262786-otxpc46a	50	37	,	,	,
cord-262786-otxpc46a	50	38	C	C	NNP
cord-262786-otxpc46a	50	39	-	-	HYPH
cord-262786-otxpc46a	50	40	X	X	NNP
cord-262786-otxpc46a	50	41	-	-	HYPH
cord-262786-otxpc46a	50	42	C	c	NN
cord-262786-otxpc46a	50	43	motif	motif	NN
cord-262786-otxpc46a	50	44	chemokine	chemokine	NN
cord-262786-otxpc46a	50	45	10	10	CD
cord-262786-otxpc46a	50	46	(	(	-LRB-
cord-262786-otxpc46a	50	47	CXCL10	CXCL10	NNP
cord-262786-otxpc46a	50	48	)	)	-RRB-
cord-262786-otxpc46a	50	49	)	)	-RRB-
cord-262786-otxpc46a	51	1	[	[	-LRB-
cord-262786-otxpc46a	51	2	24	24	CD
cord-262786-otxpc46a	51	3	]	]	-RRB-
cord-262786-otxpc46a	51	4	.	.	.
cord-262786-otxpc46a	52	1	Complicated	complicated	JJ
cord-262786-otxpc46a	52	2	cases	case	NNS
cord-262786-otxpc46a	52	3	of	of	IN
cord-262786-otxpc46a	52	4	SARS	SARS	NNP
cord-262786-otxpc46a	52	5	-	-	HYPH
cord-262786-otxpc46a	52	6	CoV	CoV	NNP
cord-262786-otxpc46a	52	7	exhibit	exhibit	NN
cord-262786-otxpc46a	52	8	higher	high	JJR
cord-262786-otxpc46a	52	9	levels	level	NNS
cord-262786-otxpc46a	52	10	of	of	IN
cord-262786-otxpc46a	52	11	proinflammatory	proinflammatory	JJ
cord-262786-otxpc46a	52	12	cytokines	cytokine	NNS
cord-262786-otxpc46a	52	13	like	like	IN
cord-262786-otxpc46a	52	14	IL-6	IL-6	NNP
cord-262786-otxpc46a	52	15	and	and	CC
cord-262786-otxpc46a	52	16	interferon	interferon	NN
cord-262786-otxpc46a	52	17	-	-	HYPH
cord-262786-otxpc46a	52	18	γ	γ	NN
cord-262786-otxpc46a	52	19	(	(	-LRB-
cord-262786-otxpc46a	52	20	IFN	IFN	NNP
cord-262786-otxpc46a	52	21	-	-	HYPH
cord-262786-otxpc46a	52	22	γ	γ	NNP
cord-262786-otxpc46a	52	23	)	)	-RRB-
cord-262786-otxpc46a	52	24	,	,	,
cord-262786-otxpc46a	52	25	making	make	VBG
cord-262786-otxpc46a	52	26	them	-PRON-	PRP
cord-262786-otxpc46a	52	27	more	more	RBR
cord-262786-otxpc46a	52	28	susceptible	susceptible	JJ
cord-262786-otxpc46a	52	29	to	to	IN
cord-262786-otxpc46a	52	30	neurologic	neurologic	JJ
cord-262786-otxpc46a	52	31	complications	complication	NNS
cord-262786-otxpc46a	52	32	[	[	-LRB-
cord-262786-otxpc46a	52	33	25	25	CD
cord-262786-otxpc46a	52	34	]	]	-RRB-
cord-262786-otxpc46a	52	35	.	.	.
cord-262786-otxpc46a	53	1	Studies	study	NNS
cord-262786-otxpc46a	53	2	on	on	IN
cord-262786-otxpc46a	53	3	postmortem	postmortem	JJ
cord-262786-otxpc46a	53	4	cases	case	NNS
cord-262786-otxpc46a	53	5	indicate	indicate	VBP
cord-262786-otxpc46a	53	6	that	that	IN
cord-262786-otxpc46a	53	7	lymphocytes	lymphocyte	NNS
cord-262786-otxpc46a	53	8	and	and	CC
cord-262786-otxpc46a	53	9	monocytes	monocyte	NNS
cord-262786-otxpc46a	53	10	infiltrate	infiltrate	VBP
cord-262786-otxpc46a	53	11	in	in	IN
cord-262786-otxpc46a	53	12	brain	brain	NN
cord-262786-otxpc46a	53	13	vessel	vessel	NN
cord-262786-otxpc46a	53	14	walls	wall	NNS
cord-262786-otxpc46a	53	15	,	,	,
cord-262786-otxpc46a	53	16	exacerbating	exacerbate	VBG
cord-262786-otxpc46a	53	17	the	the	DT
cord-262786-otxpc46a	53	18	neuronal	neuronal	JJ
cord-262786-otxpc46a	53	19	degeneration	degeneration	NN
cord-262786-otxpc46a	53	20	and	and	CC
cord-262786-otxpc46a	53	21	demyelination	demyelination	NN
cord-262786-otxpc46a	53	22	process	process	NN
cord-262786-otxpc46a	53	23	[	[	-LRB-
cord-262786-otxpc46a	53	24	17	17	CD
cord-262786-otxpc46a	53	25	]	]	-RRB-
cord-262786-otxpc46a	53	26	.	.	.
cord-262786-otxpc46a	54	1	Last	last	JJ
cord-262786-otxpc46a	54	2	but	but	CC
cord-262786-otxpc46a	54	3	not	not	RB
cord-262786-otxpc46a	54	4	least	least	JJS
cord-262786-otxpc46a	54	5	,	,	,
cord-262786-otxpc46a	54	6	indirect	indirect	JJ
cord-262786-otxpc46a	54	7	immunofluorescence	immunofluorescence	NN
cord-262786-otxpc46a	54	8	staining	staining	NN
cord-262786-otxpc46a	54	9	and	and	CC
cord-262786-otxpc46a	54	10	cell	cell	NN
cord-262786-otxpc46a	54	11	-	-	HYPH
cord-262786-otxpc46a	54	12	based	base	VBN
cord-262786-otxpc46a	54	13	enzyme	enzyme	NN
cord-262786-otxpc46a	54	14	-	-	HYPH
cord-262786-otxpc46a	54	15	linked	link	VBN
cord-262786-otxpc46a	54	16	immunosorbent	immunosorbent	JJ
cord-262786-otxpc46a	54	17	assay	assay	NN
cord-262786-otxpc46a	54	18	(	(	-LRB-
cord-262786-otxpc46a	54	19	ELISA	ELISA	NNP
cord-262786-otxpc46a	54	20	)	)	-RRB-
cord-262786-otxpc46a	54	21	study	study	VB
cord-262786-otxpc46a	54	22	in	in	IN
cord-262786-otxpc46a	54	23	the	the	DT
cord-262786-otxpc46a	54	24	serum	serum	NN
cord-262786-otxpc46a	54	25	of	of	IN
cord-262786-otxpc46a	54	26	SARS	SARS	NNP
cord-262786-otxpc46a	54	27	-	-	HYPH
cord-262786-otxpc46a	54	28	CoV	CoV	NNP
cord-262786-otxpc46a	54	29	patients	patient	NNS
cord-262786-otxpc46a	54	30	reveal	reveal	VBP
cord-262786-otxpc46a	54	31	the	the	DT
cord-262786-otxpc46a	54	32	presence	presence	NN
cord-262786-otxpc46a	54	33	of	of	IN
cord-262786-otxpc46a	54	34	IgG	IgG	NNP
cord-262786-otxpc46a	54	35	and	and	CC
cord-262786-otxpc46a	54	36	IgM	IgM	NNP
cord-262786-otxpc46a	54	37	autoantibodies	autoantibody	NNS
cord-262786-otxpc46a	54	38	as	as	RB
cord-262786-otxpc46a	54	39	well	well	RB
cord-262786-otxpc46a	54	40	as	as	IN
cord-262786-otxpc46a	54	41	complement	complement	JJ
cord-262786-otxpc46a	54	42	cytotoxicity	cytotoxicity	NN
cord-262786-otxpc46a	54	43	against	against	IN
cord-262786-otxpc46a	54	44	human	human	JJ
cord-262786-otxpc46a	54	45	epithelial	epithelial	NN
cord-262786-otxpc46a	54	46	and	and	CC
cord-262786-otxpc46a	54	47	endothelial	endothelial	JJ
cord-262786-otxpc46a	54	48	cells	cell	NNS
cord-262786-otxpc46a	54	49	[	[	-LRB-
cord-262786-otxpc46a	54	50	26	26	CD
cord-262786-otxpc46a	54	51	]	]	-RRB-
cord-262786-otxpc46a	54	52	.	.	.
cord-262786-otxpc46a	55	1	This	this	DT
cord-262786-otxpc46a	55	2	finding	finding	NN
cord-262786-otxpc46a	55	3	implies	imply	VBZ
cord-262786-otxpc46a	55	4	a	a	DT
cord-262786-otxpc46a	55	5	role	role	NN
cord-262786-otxpc46a	55	6	for	for	IN
cord-262786-otxpc46a	55	7	autoimmunity	autoimmunity	NN
cord-262786-otxpc46a	55	8	in	in	IN
cord-262786-otxpc46a	55	9	postinfectious	postinfectious	JJ
cord-262786-otxpc46a	55	10	complications	complication	NNS
cord-262786-otxpc46a	55	11	of	of	IN
cord-262786-otxpc46a	55	12	SARS	SARS	NNP
cord-262786-otxpc46a	55	13	-	-	HYPH
cord-262786-otxpc46a	55	14	CoV.	CoV.	NNP
cord-262786-otxpc46a	55	15	Middle	Middle	NNP
cord-262786-otxpc46a	55	16	East	East	NNP
cord-262786-otxpc46a	55	17	respiratory	respiratory	JJ
cord-262786-otxpc46a	55	18	syndrome	syndrome	NN
cord-262786-otxpc46a	55	19	(	(	-LRB-
cord-262786-otxpc46a	55	20	MERS	MERS	NNP
cord-262786-otxpc46a	55	21	)	)	-RRB-
cord-262786-otxpc46a	55	22	,	,	,
cord-262786-otxpc46a	55	23	another	another	DT
cord-262786-otxpc46a	55	24	respiratory	respiratory	JJ
cord-262786-otxpc46a	55	25	infection	infection	NN
cord-262786-otxpc46a	55	26	from	from	IN
cord-262786-otxpc46a	55	27	the	the	DT
cord-262786-otxpc46a	55	28	CoV	cov	NN
cord-262786-otxpc46a	55	29	family	family	NN
cord-262786-otxpc46a	55	30	,	,	,
cord-262786-otxpc46a	55	31	was	be	VBD
cord-262786-otxpc46a	55	32	first	first	RB
cord-262786-otxpc46a	55	33	reported	report	VBN
cord-262786-otxpc46a	55	34	in	in	IN
cord-262786-otxpc46a	55	35	Saudi	Saudi	NNP
cord-262786-otxpc46a	55	36	Arabia	Arabia	NNP
cord-262786-otxpc46a	55	37	in	in	IN
cord-262786-otxpc46a	55	38	2012	2012	CD
cord-262786-otxpc46a	55	39	.	.	.
cord-262786-otxpc46a	56	1	Nearly	nearly	RB
cord-262786-otxpc46a	56	2	20	20	CD
cord-262786-otxpc46a	56	3	%	%	NN
cord-262786-otxpc46a	56	4	of	of	IN
cord-262786-otxpc46a	56	5	MERS	MERS	NNP
cord-262786-otxpc46a	56	6	-	-	HYPH
cord-262786-otxpc46a	56	7	CoV	cov	NN
cord-262786-otxpc46a	56	8	patients	patient	NNS
cord-262786-otxpc46a	56	9	develop	develop	VBP
cord-262786-otxpc46a	56	10	neurologic	neurologic	JJ
cord-262786-otxpc46a	56	11	manifestations	manifestation	NNS
cord-262786-otxpc46a	56	12	during	during	IN
cord-262786-otxpc46a	56	13	the	the	DT
cord-262786-otxpc46a	56	14	disease	disease	NN
cord-262786-otxpc46a	56	15	course	course	NN
cord-262786-otxpc46a	56	16	[	[	-LRB-
cord-262786-otxpc46a	56	17	17	17	CD
cord-262786-otxpc46a	56	18	]	]	-RRB-
cord-262786-otxpc46a	56	19	.	.	.
cord-262786-otxpc46a	57	1	However	however	RB
cord-262786-otxpc46a	57	2	,	,	,
cord-262786-otxpc46a	57	3	the	the	DT
cord-262786-otxpc46a	57	4	neurologic	neurologic	JJ
cord-262786-otxpc46a	57	5	sequelae	sequela	NNS
cord-262786-otxpc46a	57	6	do	do	VBP
cord-262786-otxpc46a	57	7	not	not	RB
cord-262786-otxpc46a	57	8	always	always	RB
cord-262786-otxpc46a	57	9	occur	occur	VB
cord-262786-otxpc46a	57	10	in	in	IN
cord-262786-otxpc46a	57	11	the	the	DT
cord-262786-otxpc46a	57	12	infection	infection	NN
cord-262786-otxpc46a	57	13	process	process	NN
cord-262786-otxpc46a	57	14	and	and	CC
cord-262786-otxpc46a	57	15	might	may	MD
cord-262786-otxpc46a	57	16	manifest	manifest	VB
cord-262786-otxpc46a	57	17	after	after	IN
cord-262786-otxpc46a	57	18	a	a	DT
cord-262786-otxpc46a	57	19	delay	delay	NN
cord-262786-otxpc46a	57	20	of	of	IN
cord-262786-otxpc46a	57	21	2	2	CD
cord-262786-otxpc46a	57	22	or	or	CC
cord-262786-otxpc46a	57	23	3	3	CD
cord-262786-otxpc46a	57	24	weeks	week	NNS
cord-262786-otxpc46a	57	25	[	[	-LRB-
cord-262786-otxpc46a	57	26	17	17	CD
cord-262786-otxpc46a	57	27	]	]	-RRB-
cord-262786-otxpc46a	57	28	.	.	.
cord-262786-otxpc46a	58	1	Stroke	stroke	NN
cord-262786-otxpc46a	58	2	,	,	,
cord-262786-otxpc46a	58	3	encephalopathy	encephalopathy	NN
cord-262786-otxpc46a	58	4	,	,	,
cord-262786-otxpc46a	58	5	seizure	seizure	NN
cord-262786-otxpc46a	58	6	,	,	,
cord-262786-otxpc46a	58	7	GBS	GBS	NNP
cord-262786-otxpc46a	58	8	,	,	,
cord-262786-otxpc46a	58	9	and	and	CC
cord-262786-otxpc46a	58	10	brainstem	brainstem	NN
cord-262786-otxpc46a	58	11	involvement	involvement	NN
cord-262786-otxpc46a	58	12	could	could	MD
cord-262786-otxpc46a	58	13	accompany	accompany	VB
cord-262786-otxpc46a	58	14	MERS	MERS	NNP
cord-262786-otxpc46a	58	15	infection	infection	NN
cord-262786-otxpc46a	58	16	[	[	-LRB-
cord-262786-otxpc46a	58	17	16	16	CD
cord-262786-otxpc46a	58	18	,	,	,
cord-262786-otxpc46a	58	19	17	17	CD
cord-262786-otxpc46a	58	20	]	]	-RRB-
cord-262786-otxpc46a	58	21	.	.	.
cord-262786-otxpc46a	59	1	Brain	Brain	NNP
cord-262786-otxpc46a	59	2	MRI	MRI	NNP
cord-262786-otxpc46a	59	3	in	in	IN
cord-262786-otxpc46a	59	4	neurologically	neurologically	RB
cord-262786-otxpc46a	59	5	affected	affected	JJ
cord-262786-otxpc46a	59	6	MERS	MERS	NNP
cord-262786-otxpc46a	59	7	-	-	HYPH
cord-262786-otxpc46a	59	8	CoV	cov	NN
cord-262786-otxpc46a	59	9	patients	patient	NNS
cord-262786-otxpc46a	59	10	reveal	reveal	VBP
cord-262786-otxpc46a	59	11	hyperintense	hyperintense	NN
cord-262786-otxpc46a	59	12	lesions	lesion	NNS
cord-262786-otxpc46a	59	13	in	in	IN
cord-262786-otxpc46a	59	14	white	white	JJ
cord-262786-otxpc46a	59	15	matter	matter	NN
cord-262786-otxpc46a	59	16	and	and	CC
cord-262786-otxpc46a	59	17	subcortical	subcortical	JJ
cord-262786-otxpc46a	59	18	frontal	frontal	JJ
cord-262786-otxpc46a	59	19	,	,	,
cord-262786-otxpc46a	59	20	parietal	parietal	JJ
cord-262786-otxpc46a	59	21	,	,	,
cord-262786-otxpc46a	59	22	and	and	CC
cord-262786-otxpc46a	59	23	temporal	temporal	JJ
cord-262786-otxpc46a	59	24	lobes	lobe	NNS
cord-262786-otxpc46a	59	25	,	,	,
cord-262786-otxpc46a	59	26	along	along	IN
cord-262786-otxpc46a	59	27	with	with	IN
cord-262786-otxpc46a	59	28	basal	basal	NN
cord-262786-otxpc46a	59	29	ganglia	ganglion	NNS
cord-262786-otxpc46a	59	30	and	and	CC
cord-262786-otxpc46a	59	31	corpus	corpus	NNP
cord-262786-otxpc46a	59	32	callosum	callosum	NNP
cord-262786-otxpc46a	59	33	[	[	-LRB-
cord-262786-otxpc46a	59	34	27	27	CD
cord-262786-otxpc46a	59	35	]	]	-RRB-
cord-262786-otxpc46a	59	36	.	.	.
cord-262786-otxpc46a	60	1	The	the	DT
cord-262786-otxpc46a	60	2	mechanisms	mechanism	NNS
cord-262786-otxpc46a	60	3	of	of	IN
cord-262786-otxpc46a	60	4	neurological	neurological	JJ
cord-262786-otxpc46a	60	5	involvement	involvement	NN
cord-262786-otxpc46a	60	6	in	in	IN
cord-262786-otxpc46a	60	7	MERS	MERS	NNP
cord-262786-otxpc46a	60	8	-	-	HYPH
cord-262786-otxpc46a	60	9	CoV	CoV	NNP
cord-262786-otxpc46a	60	10	are	be	VBP
cord-262786-otxpc46a	60	11	almost	almost	RB
cord-262786-otxpc46a	60	12	similar	similar	JJ
cord-262786-otxpc46a	60	13	to	to	IN
cord-262786-otxpc46a	60	14	SARS	SARS	NNP
cord-262786-otxpc46a	60	15	-	-	HYPH
cord-262786-otxpc46a	60	16	CoV	CoV	NNP
cord-262786-otxpc46a	60	17	,	,	,
cord-262786-otxpc46a	60	18	with	with	IN
cord-262786-otxpc46a	60	19	a	a	DT
cord-262786-otxpc46a	60	20	surge	surge	NN
cord-262786-otxpc46a	60	21	in	in	IN
cord-262786-otxpc46a	60	22	circulating	circulate	VBG
cord-262786-otxpc46a	60	23	cytokine	cytokine	NN
cord-262786-otxpc46a	60	24	levels	level	NNS
cord-262786-otxpc46a	60	25	and	and	CC
cord-262786-otxpc46a	60	26	a	a	DT
cord-262786-otxpc46a	60	27	role	role	NN
cord-262786-otxpc46a	60	28	for	for	IN
cord-262786-otxpc46a	60	29	autoreactive	autoreactive	JJ
cord-262786-otxpc46a	60	30	autoantibodies	autoantibody	NNS
cord-262786-otxpc46a	60	31	[	[	-LRB-
cord-262786-otxpc46a	60	32	28	28	CD
cord-262786-otxpc46a	60	33	,	,	,
cord-262786-otxpc46a	60	34	29	29	CD
cord-262786-otxpc46a	60	35	]	]	-RRB-
cord-262786-otxpc46a	60	36	.	.	.
cord-262786-otxpc46a	61	1	SARS	SARS	NNP
cord-262786-otxpc46a	61	2	-	-	HYPH
cord-262786-otxpc46a	61	3	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	61	4	invasion	invasion	NN
cord-262786-otxpc46a	61	5	throughout	throughout	IN
cord-262786-otxpc46a	61	6	the	the	DT
cord-262786-otxpc46a	61	7	CNS	CNS	NNP
cord-262786-otxpc46a	61	8	can	can	MD
cord-262786-otxpc46a	61	9	be	be	VB
cord-262786-otxpc46a	61	10	divided	divide	VBN
cord-262786-otxpc46a	61	11	into	into	IN
cord-262786-otxpc46a	61	12	three	three	CD
cord-262786-otxpc46a	61	13	phases	phase	NNS
cord-262786-otxpc46a	61	14	:	:	:
cord-262786-otxpc46a	61	15	first	first	RB
cord-262786-otxpc46a	61	16	,	,	,
cord-262786-otxpc46a	61	17	the	the	DT
cord-262786-otxpc46a	61	18	virus	virus	NN
cord-262786-otxpc46a	61	19	directly	directly	RB
cord-262786-otxpc46a	61	20	invades	invade	VBZ
cord-262786-otxpc46a	61	21	the	the	DT
cord-262786-otxpc46a	61	22	brain	brain	NN
cord-262786-otxpc46a	61	23	through	through	IN
cord-262786-otxpc46a	61	24	vascular	vascular	JJ
cord-262786-otxpc46a	61	25	or	or	CC
cord-262786-otxpc46a	61	26	retrograde	retrograde	JJ
cord-262786-otxpc46a	61	27	axonal	axonal	JJ
cord-262786-otxpc46a	61	28	transport	transport	NN
cord-262786-otxpc46a	61	29	within	within	IN
cord-262786-otxpc46a	61	30	the	the	DT
cord-262786-otxpc46a	61	31	cribriform	cribriform	NNP
cord-262786-otxpc46a	61	32	plate	plate	NN
cord-262786-otxpc46a	61	33	,	,	,
cord-262786-otxpc46a	61	34	and	and	CC
cord-262786-otxpc46a	61	35	thus	thus	RB
cord-262786-otxpc46a	61	36	,	,	,
cord-262786-otxpc46a	61	37	the	the	DT
cord-262786-otxpc46a	61	38	viral	viral	JJ
cord-262786-otxpc46a	61	39	load	load	NN
cord-262786-otxpc46a	61	40	increases	increase	NNS
cord-262786-otxpc46a	61	41	in	in	IN
cord-262786-otxpc46a	61	42	the	the	DT
cord-262786-otxpc46a	61	43	CSF	CSF	NNP
cord-262786-otxpc46a	61	44	[	[	-LRB-
cord-262786-otxpc46a	61	45	4	4	CD
cord-262786-otxpc46a	61	46	]	]	-RRB-
cord-262786-otxpc46a	61	47	.	.	.
cord-262786-otxpc46a	62	1	Second	second	RB
cord-262786-otxpc46a	62	2	,	,	,
cord-262786-otxpc46a	62	3	the	the	DT
cord-262786-otxpc46a	62	4	virus	virus	NN
cord-262786-otxpc46a	62	5	infects	infect	VBZ
cord-262786-otxpc46a	62	6	,	,	,
cord-262786-otxpc46a	62	7	replicates	replicate	VBZ
cord-262786-otxpc46a	62	8	in	in	IN
cord-262786-otxpc46a	62	9	,	,	,
cord-262786-otxpc46a	62	10	and	and	CC
cord-262786-otxpc46a	62	11	kills	kill	VBZ
cord-262786-otxpc46a	62	12	neural	neural	JJ
cord-262786-otxpc46a	62	13	cells	cell	NNS
cord-262786-otxpc46a	62	14	through	through	IN
cord-262786-otxpc46a	62	15	ACE-2	ACE-2	NNP
cord-262786-otxpc46a	62	16	receptors	receptor	NNS
cord-262786-otxpc46a	62	17	[	[	-LRB-
cord-262786-otxpc46a	62	18	30	30	CD
cord-262786-otxpc46a	62	19	]	]	-RRB-
cord-262786-otxpc46a	62	20	.	.	.
cord-262786-otxpc46a	63	1	Third	third	RB
cord-262786-otxpc46a	63	2	,	,	,
cord-262786-otxpc46a	63	3	the	the	DT
cord-262786-otxpc46a	63	4	immunemediated	immunemediated	JJ
cord-262786-otxpc46a	63	5	response	response	NN
cord-262786-otxpc46a	63	6	against	against	IN
cord-262786-otxpc46a	63	7	the	the	DT
cord-262786-otxpc46a	63	8	virus	virus	NN
cord-262786-otxpc46a	63	9	can	can	MD
cord-262786-otxpc46a	63	10	indirectly	indirectly	RB
cord-262786-otxpc46a	63	11	involve	involve	VB
cord-262786-otxpc46a	63	12	the	the	DT
cord-262786-otxpc46a	63	13	brain	brain	NN
cord-262786-otxpc46a	63	14	,	,	,
cord-262786-otxpc46a	63	15	although	although	IN
cord-262786-otxpc46a	63	16	the	the	DT
cord-262786-otxpc46a	63	17	viral	viral	JJ
cord-262786-otxpc46a	63	18	replication	replication	NN
cord-262786-otxpc46a	63	19	declines	decline	NNS
cord-262786-otxpc46a	63	20	in	in	IN
cord-262786-otxpc46a	63	21	this	this	DT
cord-262786-otxpc46a	63	22	final	final	JJ
cord-262786-otxpc46a	63	23	phase	phase	NN
cord-262786-otxpc46a	63	24	[	[	-LRB-
cord-262786-otxpc46a	63	25	31	31	CD
cord-262786-otxpc46a	63	26	]	]	-RRB-
cord-262786-otxpc46a	64	1	(	(	-LRB-
cord-262786-otxpc46a	64	2	Fig	Fig	NNP
cord-262786-otxpc46a	64	3	.	.	NNP
cord-262786-otxpc46a	64	4	1	1	CD
cord-262786-otxpc46a	64	5	)	)	-RRB-
cord-262786-otxpc46a	64	6	.	.	.
cord-262786-otxpc46a	65	1	Recent	recent	JJ
cord-262786-otxpc46a	65	2	evidence	evidence	NN
cord-262786-otxpc46a	65	3	shows	show	VBZ
cord-262786-otxpc46a	65	4	that	that	IN
cord-262786-otxpc46a	65	5	the	the	DT
cord-262786-otxpc46a	65	6	third	third	JJ
cord-262786-otxpc46a	65	7	phase	phase	NN
cord-262786-otxpc46a	65	8	(	(	-LRB-
cord-262786-otxpc46a	65	9	also	also	RB
cord-262786-otxpc46a	65	10	known	know	VBN
cord-262786-otxpc46a	65	11	as	as	IN
cord-262786-otxpc46a	65	12	SIRS	SIRS	NNP
cord-262786-otxpc46a	65	13	)	)	-RRB-
cord-262786-otxpc46a	65	14	accounts	account	VBZ
cord-262786-otxpc46a	65	15	for	for	IN
cord-262786-otxpc46a	65	16	the	the	DT
cord-262786-otxpc46a	65	17	majority	majority	NN
cord-262786-otxpc46a	65	18	of	of	IN
cord-262786-otxpc46a	65	19	CNS	CNS	NNP
cord-262786-otxpc46a	65	20	disturbances	disturbance	NNS
cord-262786-otxpc46a	65	21	mediated	mediate	VBN
cord-262786-otxpc46a	65	22	by	by	IN
cord-262786-otxpc46a	65	23	SARS	SARS	NNP
cord-262786-otxpc46a	65	24	-	-	HYPH
cord-262786-otxpc46a	65	25	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	65	26	[	[	-LRB-
cord-262786-otxpc46a	65	27	31	31	CD
cord-262786-otxpc46a	65	28	]	]	-RRB-
cord-262786-otxpc46a	65	29	.	.	.
cord-262786-otxpc46a	66	1	SARS	SARS	NNP
cord-262786-otxpc46a	66	2	-	-	HYPH
cord-262786-otxpc46a	66	3	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	66	4	invades	invade	VBZ
cord-262786-otxpc46a	66	5	astrocytes	astrocyte	NNS
cord-262786-otxpc46a	66	6	,	,	,
cord-262786-otxpc46a	66	7	macrophages	macrophage	NNS
cord-262786-otxpc46a	66	8	,	,	,
cord-262786-otxpc46a	66	9	and	and	CC
cord-262786-otxpc46a	66	10	microglia	microglia	NN
cord-262786-otxpc46a	66	11	in	in	IN
cord-262786-otxpc46a	66	12	CNS	CNS	NNP
cord-262786-otxpc46a	66	13	and	and	CC
cord-262786-otxpc46a	66	14	induces	induce	VBZ
cord-262786-otxpc46a	66	15	a	a	DT
cord-262786-otxpc46a	66	16	proinflammatory	proinflammatory	JJ
cord-262786-otxpc46a	66	17	state	state	NN
cord-262786-otxpc46a	66	18	characterized	characterize	VBN
cord-262786-otxpc46a	66	19	by	by	IN
cord-262786-otxpc46a	66	20	increased	increase	VBN
cord-262786-otxpc46a	66	21	levels	level	NNS
cord-262786-otxpc46a	66	22	of	of	IN
cord-262786-otxpc46a	66	23	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	66	24	mediators	mediator	NNS
cord-262786-otxpc46a	66	25	including	include	VBG
cord-262786-otxpc46a	66	26	interleukin-1β	interleukin-1β	NNP
cord-262786-otxpc46a	66	27	(	(	-LRB-
cord-262786-otxpc46a	66	28	IL-1	IL-1	NNP
cord-262786-otxpc46a	66	29	β	β	NNP
cord-262786-otxpc46a	66	30	)	)	-RRB-
cord-262786-otxpc46a	66	31	,	,	,
cord-262786-otxpc46a	66	32	interleukin-2	interleukin-2	IN
cord-262786-otxpc46a	66	33	(	(	-LRB-
cord-262786-otxpc46a	66	34	IL-2	IL-2	NNP
cord-262786-otxpc46a	66	35	)	)	-RRB-
cord-262786-otxpc46a	66	36	,	,	.
cord-262786-otxpc46a	67	1	IL-2	IL-2	NNP
cord-262786-otxpc46a	68	1	receptor	receptor	NN
cord-262786-otxpc46a	68	2	(	(	-LRB-
cord-262786-otxpc46a	68	3	IL-2R	IL-2R	NNP
cord-262786-otxpc46a	68	4	)	)	-RRB-
cord-262786-otxpc46a	68	5	,	,	,
cord-262786-otxpc46a	68	6	interleukin-4	interleukin-4	NNP
cord-262786-otxpc46a	68	7	(	(	-LRB-
cord-262786-otxpc46a	68	8	IL-4	IL-4	NNP
cord-262786-otxpc46a	68	9	)	)	-RRB-
cord-262786-otxpc46a	68	10	,	,	,
cord-262786-otxpc46a	68	11	IL-6	IL-6	NNP
cord-262786-otxpc46a	68	12	,	,	,
cord-262786-otxpc46a	68	13	interleukin-10	interleukin-10	FW
cord-262786-otxpc46a	68	14	(	(	-LRB-
cord-262786-otxpc46a	68	15	IL-10	IL-10	NNP
cord-262786-otxpc46a	68	16	)	)	-RRB-
cord-262786-otxpc46a	68	17	,	,	,
cord-262786-otxpc46a	68	18	interleukin-18	interleukin-18	NN
cord-262786-otxpc46a	68	19	(	(	-LRB-
cord-262786-otxpc46a	68	20	IL-18	IL-18	NNP
cord-262786-otxpc46a	68	21	)	)	-RRB-
cord-262786-otxpc46a	68	22	,	,	,
cord-262786-otxpc46a	68	23	IFN	IFN	NNP
cord-262786-otxpc46a	68	24	-	-	HYPH
cord-262786-otxpc46a	68	25	γ	γ	NNP
cord-262786-otxpc46a	68	26	,	,	,
cord-262786-otxpc46a	68	27	TNF	TNF	NNP
cord-262786-otxpc46a	68	28	-	-	HYPH
cord-262786-otxpc46a	68	29	α	α	NNP
cord-262786-otxpc46a	68	30	,	,	,
cord-262786-otxpc46a	68	31	granulocyte	granulocyte	NN
cord-262786-otxpc46a	68	32	colony	colony	NN
cord-262786-otxpc46a	68	33	-	-	HYPH
cord-262786-otxpc46a	68	34	stimulating	stimulate	VBG
cord-262786-otxpc46a	68	35	factor	factor	NN
cord-262786-otxpc46a	68	36	(	(	-LRB-
cord-262786-otxpc46a	68	37	GCSF	GCSF	NNP
cord-262786-otxpc46a	68	38	)	)	-RRB-
cord-262786-otxpc46a	68	39	,	,	,
cord-262786-otxpc46a	68	40	monocyte	monocyte	NNP
cord-262786-otxpc46a	68	41	chemoattractant	chemoattractant	NNP
cord-262786-otxpc46a	68	42	protein	protein	NNP
cord-262786-otxpc46a	68	43	1	1	CD
cord-262786-otxpc46a	68	44	(	(	-LRB-
cord-262786-otxpc46a	68	45	MCP-1	MCP-1	NNP
cord-262786-otxpc46a	68	46	)	)	-RRB-
cord-262786-otxpc46a	69	1	,	,	,
cord-262786-otxpc46a	69	2	macrophage	macrophage	NN
cord-262786-otxpc46a	69	3	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	69	4	protein	protein	NN
cord-262786-otxpc46a	70	1	1-α	1-α	CD
cord-262786-otxpc46a	71	1	(	(	-LRB-
cord-262786-otxpc46a	71	2	MIP-1α	MIP-1α	NNP
cord-262786-otxpc46a	71	3	)	)	-RRB-
cord-262786-otxpc46a	71	4	,	,	,
cord-262786-otxpc46a	71	5	CXCL10	CXCL10	NNP
cord-262786-otxpc46a	71	6	,	,	,
cord-262786-otxpc46a	71	7	CCL2	CCL2	NNP
cord-262786-otxpc46a	71	8	,	,	,
cord-262786-otxpc46a	71	9	and	and	CC
cord-262786-otxpc46a	71	10	C	c	NN
cord-262786-otxpc46a	71	11	-	-	HYPH
cord-262786-otxpc46a	71	12	reaction	reaction	NN
cord-262786-otxpc46a	71	13	protein	protein	NN
cord-262786-otxpc46a	71	14	(	(	-LRB-
cord-262786-otxpc46a	71	15	CRP	CRP	NNP
cord-262786-otxpc46a	71	16	)	)	-RRB-
cord-262786-otxpc46a	71	17	[	[	-LRB-
cord-262786-otxpc46a	71	18	25	25	CD
cord-262786-otxpc46a	71	19	]	]	-RRB-
cord-262786-otxpc46a	71	20	.	.	.
cord-262786-otxpc46a	72	1	Also	also	RB
cord-262786-otxpc46a	72	2	,	,	,
cord-262786-otxpc46a	72	3	SARS	SARS	NNP
cord-262786-otxpc46a	72	4	-	-	HYPH
cord-262786-otxpc46a	72	5	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	72	6	induces	induce	VBZ
cord-262786-otxpc46a	72	7	in	in	IN
cord-262786-otxpc46a	72	8	vitro	vitro	FW
cord-262786-otxpc46a	72	9	expression	expression	NN
cord-262786-otxpc46a	72	10	of	of	IN
cord-262786-otxpc46a	72	11	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	72	12	cytokines	cytokine	NNS
cord-262786-otxpc46a	72	13	such	such	JJ
cord-262786-otxpc46a	72	14	as	as	IN
cord-262786-otxpc46a	72	15	IL-6	IL-6	NNP
cord-262786-otxpc46a	72	16	,	,	,
cord-262786-otxpc46a	72	17	interleukin-12	interleukin-12	XX
cord-262786-otxpc46a	72	18	(	(	-LRB-
cord-262786-otxpc46a	72	19	IL-12	IL-12	NNP
cord-262786-otxpc46a	72	20	)	)	-RRB-
cord-262786-otxpc46a	72	21	,	,	,
cord-262786-otxpc46a	72	22	interleukin-15	interleukin-15	FW
cord-262786-otxpc46a	72	23	(	(	-LRB-
cord-262786-otxpc46a	72	24	IL-15	IL-15	NNP
cord-262786-otxpc46a	72	25	)	)	-RRB-
cord-262786-otxpc46a	72	26	,	,	,
cord-262786-otxpc46a	72	27	and	and	CC
cord-262786-otxpc46a	72	28	TNF	TNF	NNP
cord-262786-otxpc46a	72	29	-	-	HYPH
cord-262786-otxpc46a	72	30	α	α	NN
cord-262786-otxpc46a	72	31	in	in	IN
cord-262786-otxpc46a	72	32	glial	glial	JJ
cord-262786-otxpc46a	72	33	cells	cell	NNS
cord-262786-otxpc46a	72	34	[	[	-LRB-
cord-262786-otxpc46a	72	35	17	17	CD
cord-262786-otxpc46a	72	36	]	]	-RRB-
cord-262786-otxpc46a	72	37	.	.	.
cord-262786-otxpc46a	73	1	Severe	severe	JJ
cord-262786-otxpc46a	73	2	cases	case	NNS
cord-262786-otxpc46a	73	3	of	of	IN
cord-262786-otxpc46a	73	4	the	the	DT
cord-262786-otxpc46a	73	5	disease	disease	NN
cord-262786-otxpc46a	73	6	compared	compare	VBN
cord-262786-otxpc46a	73	7	with	with	IN
cord-262786-otxpc46a	73	8	non	non	JJ
cord-262786-otxpc46a	73	9	-	-	JJ
cord-262786-otxpc46a	73	10	severe	severe	JJ
cord-262786-otxpc46a	73	11	cases	case	NNS
cord-262786-otxpc46a	73	12	tend	tend	VBP
cord-262786-otxpc46a	73	13	to	to	TO
cord-262786-otxpc46a	73	14	increase	increase	VB
cord-262786-otxpc46a	73	15	in	in	IN
cord-262786-otxpc46a	73	16	circulatory	circulatory	JJ
cord-262786-otxpc46a	73	17	levels	level	NNS
cord-262786-otxpc46a	73	18	of	of	IN
cord-262786-otxpc46a	73	19	IL-2	IL-2	NNP
cord-262786-otxpc46a	73	20	,	,	,
cord-262786-otxpc46a	73	21	IL-2R	IL-2R	NNP
cord-262786-otxpc46a	73	22	,	,	,
cord-262786-otxpc46a	73	23	IL-6	IL-6	NNP
cord-262786-otxpc46a	73	24	,	,	,
cord-262786-otxpc46a	73	25	IL-10	IL-10	NNP
cord-262786-otxpc46a	73	26	,	,	,
cord-262786-otxpc46a	73	27	IFN	IFN	NNP
cord-262786-otxpc46a	73	28	-	-	HYPH
cord-262786-otxpc46a	73	29	γ	γ	NNP
cord-262786-otxpc46a	73	30	,	,	,
cord-262786-otxpc46a	73	31	TNF	TNF	NNP
cord-262786-otxpc46a	73	32	-	-	HYPH
cord-262786-otxpc46a	73	33	α	α	NNP
cord-262786-otxpc46a	73	34	,	,	,
cord-262786-otxpc46a	73	35	CCL2	CCL2	NNP
cord-262786-otxpc46a	73	36	,	,	,
cord-262786-otxpc46a	73	37	procalcitonin	procalcitonin	NNS
cord-262786-otxpc46a	73	38	(	(	-LRB-
cord-262786-otxpc46a	73	39	PCT	PCT	NNP
cord-262786-otxpc46a	73	40	)	)	-RRB-
cord-262786-otxpc46a	73	41	,	,	,
cord-262786-otxpc46a	73	42	CRP	CRP	NNP
cord-262786-otxpc46a	73	43	,	,	,
cord-262786-otxpc46a	73	44	erythrocyte	erythrocyte	NN
cord-262786-otxpc46a	73	45	sedimentation	sedimentation	NN
cord-262786-otxpc46a	73	46	rate	rate	NN
cord-262786-otxpc46a	73	47	(	(	-LRB-
cord-262786-otxpc46a	73	48	ESR	ESR	NNP
cord-262786-otxpc46a	73	49	)	)	-RRB-
cord-262786-otxpc46a	73	50	,	,	,
cord-262786-otxpc46a	73	51	and	and	CC
cord-262786-otxpc46a	73	52	white	white	JJ
cord-262786-otxpc46a	73	53	blood	blood	NN
cord-262786-otxpc46a	73	54	cell	cell	NN
cord-262786-otxpc46a	73	55	(	(	-LRB-
cord-262786-otxpc46a	73	56	WBC	WBC	NNP
cord-262786-otxpc46a	73	57	)	)	-RRB-
cord-262786-otxpc46a	73	58	and	and	CC
cord-262786-otxpc46a	73	59	neutrophil	neutrophil	NN
cord-262786-otxpc46a	73	60	counts	count	NNS
cord-262786-otxpc46a	73	61	and	and	CC
cord-262786-otxpc46a	73	62	decrease	decrease	NN
cord-262786-otxpc46a	73	63	in	in	IN
cord-262786-otxpc46a	73	64	total	total	JJ
cord-262786-otxpc46a	73	65	lymphocyte	lymphocyte	NN
cord-262786-otxpc46a	73	66	,	,	,
cord-262786-otxpc46a	73	67	CD4	CD4	NNP
cord-262786-otxpc46a	73	68	+	+	CC
cord-262786-otxpc46a	73	69	T	T	NNP
cord-262786-otxpc46a	73	70	lymphocyte	lymphocyte	NN
cord-262786-otxpc46a	73	71	,	,	,
cord-262786-otxpc46a	73	72	and	and	CC
cord-262786-otxpc46a	73	73	CD8	CD8	NNP
cord-262786-otxpc46a	73	74	+	+	CC
cord-262786-otxpc46a	73	75	T	T	NNP
cord-262786-otxpc46a	73	76	lymphocyte	lymphocyte	NN
cord-262786-otxpc46a	73	77	counts	count	VBZ
cord-262786-otxpc46a	73	78	,	,	,
cord-262786-otxpc46a	73	79	while	while	IN
cord-262786-otxpc46a	73	80	B	b	NN
cord-262786-otxpc46a	73	81	cell	cell	NN
cord-262786-otxpc46a	73	82	count	count	NN
cord-262786-otxpc46a	73	83	remains	remain	VBZ
cord-262786-otxpc46a	73	84	in	in	IN
cord-262786-otxpc46a	73	85	the	the	DT
cord-262786-otxpc46a	73	86	normal	normal	JJ
cord-262786-otxpc46a	73	87	range	range	NN
cord-262786-otxpc46a	73	88	[	[	-LRB-
cord-262786-otxpc46a	73	89	24	24	CD
cord-262786-otxpc46a	73	90	,	,	,
cord-262786-otxpc46a	73	91	32	32	CD
cord-262786-otxpc46a	73	92	,	,	,
cord-262786-otxpc46a	73	93	33	33	CD
cord-262786-otxpc46a	73	94	]	]	-RRB-
cord-262786-otxpc46a	73	95	.	.	.
cord-262786-otxpc46a	74	1	Also	also	RB
cord-262786-otxpc46a	74	2	,	,	,
cord-262786-otxpc46a	74	3	antibodies	antibody	NNS
cord-262786-otxpc46a	74	4	(	(	-LRB-
cord-262786-otxpc46a	74	5	namely	namely	RB
cord-262786-otxpc46a	74	6	IgG	IgG	NNP
cord-262786-otxpc46a	74	7	,	,	,
cord-262786-otxpc46a	74	8	IgM	IgM	NNP
cord-262786-otxpc46a	74	9	,	,	,
cord-262786-otxpc46a	74	10	and	and	CC
cord-262786-otxpc46a	74	11	IgA	IgA	NNP
cord-262786-otxpc46a	74	12	)	)	-RRB-
cord-262786-otxpc46a	74	13	against	against	IN
cord-262786-otxpc46a	74	14	viral	viral	JJ
cord-262786-otxpc46a	74	15	particles	particle	NNS
cord-262786-otxpc46a	74	16	rise	rise	VBP
cord-262786-otxpc46a	74	17	in	in	IN
cord-262786-otxpc46a	74	18	the	the	DT
cord-262786-otxpc46a	74	19	disease	disease	NN
cord-262786-otxpc46a	74	20	course	course	NN
cord-262786-otxpc46a	74	21	[	[	-LRB-
cord-262786-otxpc46a	74	22	34	34	CD
cord-262786-otxpc46a	74	23	]	]	-RRB-
cord-262786-otxpc46a	74	24	.	.	.
cord-262786-otxpc46a	75	1	Seroconversion	seroconversion	NN
cord-262786-otxpc46a	75	2	of	of	IN
cord-262786-otxpc46a	75	3	IgM	IgM	NNP
cord-262786-otxpc46a	75	4	and	and	CC
cord-262786-otxpc46a	75	5	IgG	IgG	NNP
cord-262786-otxpc46a	75	6	antibodies	antibody	NNS
cord-262786-otxpc46a	75	7	begins	begin	VBZ
cord-262786-otxpc46a	75	8	4	4	CD
cord-262786-otxpc46a	75	9	days	day	NNS
cord-262786-otxpc46a	75	10	after	after	IN
cord-262786-otxpc46a	75	11	the	the	DT
cord-262786-otxpc46a	75	12	symptom	symptom	NN
cord-262786-otxpc46a	75	13	onset	onset	NN
cord-262786-otxpc46a	75	14	[	[	-LRB-
cord-262786-otxpc46a	75	15	35	35	CD
cord-262786-otxpc46a	75	16	]	]	-RRB-
cord-262786-otxpc46a	75	17	.	.	.
cord-262786-otxpc46a	76	1	Although	although	IN
cord-262786-otxpc46a	76	2	the	the	DT
cord-262786-otxpc46a	76	3	median	median	JJ
cord-262786-otxpc46a	76	4	time	time	NN
cord-262786-otxpc46a	76	5	for	for	IN
cord-262786-otxpc46a	76	6	seropositivity	seropositivity	NN
cord-262786-otxpc46a	76	7	against	against	IN
cord-262786-otxpc46a	76	8	the	the	DT
cord-262786-otxpc46a	76	9	receptor	receptor	NN
cord-262786-otxpc46a	76	10	-	-	HYPH
cord-262786-otxpc46a	76	11	binding	bind	VBG
cord-262786-otxpc46a	76	12	domain	domain	NN
cord-262786-otxpc46a	76	13	of	of	IN
cord-262786-otxpc46a	76	14	the	the	DT
cord-262786-otxpc46a	76	15	virus	virus	NN
cord-262786-otxpc46a	76	16	in	in	IN
cord-262786-otxpc46a	76	17	the	the	DT
cord-262786-otxpc46a	76	18	serum	serum	NN
cord-262786-otxpc46a	76	19	is	be	VBZ
cord-262786-otxpc46a	76	20	equal	equal	JJ
cord-262786-otxpc46a	76	21	for	for	IN
cord-262786-otxpc46a	76	22	different	different	JJ
cord-262786-otxpc46a	76	23	isotypes	isotypes	NNP
cord-262786-otxpc46a	76	24	,	,	,
cord-262786-otxpc46a	76	25	IgG	IgG	NNP
cord-262786-otxpc46a	76	26	is	be	VBZ
cord-262786-otxpc46a	76	27	estimated	estimate	VBN
cord-262786-otxpc46a	76	28	to	to	TO
cord-262786-otxpc46a	76	29	remain	remain	VB
cord-262786-otxpc46a	76	30	positive	positive	JJ
cord-262786-otxpc46a	76	31	in	in	IN
cord-262786-otxpc46a	76	32	the	the	DT
cord-262786-otxpc46a	76	33	serum	serum	NN
cord-262786-otxpc46a	76	34	for	for	IN
cord-262786-otxpc46a	76	35	75	75	CD
cord-262786-otxpc46a	76	36	days	day	NNS
cord-262786-otxpc46a	76	37	,	,	,
cord-262786-otxpc46a	76	38	that	that	DT
cord-262786-otxpc46a	76	39	is	be	VBZ
cord-262786-otxpc46a	76	40	the	the	DT
cord-262786-otxpc46a	76	41	longest	long	JJS
cord-262786-otxpc46a	76	42	period	period	NN
cord-262786-otxpc46a	76	43	comparing	compare	VBG
cord-262786-otxpc46a	76	44	with	with	IN
cord-262786-otxpc46a	76	45	IgA	IgA	NNP
cord-262786-otxpc46a	76	46	and	and	CC
cord-262786-otxpc46a	76	47	IgM	IgM	NNP
cord-262786-otxpc46a	76	48	,	,	,
cord-262786-otxpc46a	76	49	lasting	last	VBG
cord-262786-otxpc46a	76	50	for	for	IN
cord-262786-otxpc46a	76	51	51	51	CD
cord-262786-otxpc46a	76	52	and	and	CC
cord-262786-otxpc46a	76	53	47	47	CD
cord-262786-otxpc46a	76	54	days	day	NNS
cord-262786-otxpc46a	76	55	,	,	,
cord-262786-otxpc46a	76	56	respectively	respectively	RB
cord-262786-otxpc46a	76	57	[	[	-LRB-
cord-262786-otxpc46a	76	58	34	34	CD
cord-262786-otxpc46a	76	59	]	]	-RRB-
cord-262786-otxpc46a	76	60	.	.	.
cord-262786-otxpc46a	77	1	Of	of	IN
cord-262786-otxpc46a	77	2	note	note	NN
cord-262786-otxpc46a	77	3	,	,	,
cord-262786-otxpc46a	77	4	the	the	DT
cord-262786-otxpc46a	77	5	social	social	JJ
cord-262786-otxpc46a	77	6	isolation	isolation	NN
cord-262786-otxpc46a	77	7	and	and	CC
cord-262786-otxpc46a	77	8	the	the	DT
cord-262786-otxpc46a	77	9	resultant	resultant	JJ
cord-262786-otxpc46a	77	10	stress	stress	NN
cord-262786-otxpc46a	77	11	exacerbate	exacerbate	VBP
cord-262786-otxpc46a	77	12	the	the	DT
cord-262786-otxpc46a	77	13	aforementioned	aforementioned	JJ
cord-262786-otxpc46a	77	14	cytokine	cytokine	NN
cord-262786-otxpc46a	77	15	release	release	NN
cord-262786-otxpc46a	77	16	in	in	IN
cord-262786-otxpc46a	77	17	affected	affected	JJ
cord-262786-otxpc46a	77	18	patients	patient	NNS
cord-262786-otxpc46a	77	19	[	[	-LRB-
cord-262786-otxpc46a	77	20	25	25	CD
cord-262786-otxpc46a	77	21	]	]	-RRB-
cord-262786-otxpc46a	77	22	.	.	.
cord-262786-otxpc46a	78	1	Cytokine	cytokine	NN
cord-262786-otxpc46a	78	2	storm	storm	NN
cord-262786-otxpc46a	78	3	is	be	VBZ
cord-262786-otxpc46a	78	4	a	a	DT
cord-262786-otxpc46a	78	5	term	term	NN
cord-262786-otxpc46a	78	6	used	use	VBN
cord-262786-otxpc46a	78	7	for	for	IN
cord-262786-otxpc46a	78	8	the	the	DT
cord-262786-otxpc46a	78	9	extreme	extreme	JJ
cord-262786-otxpc46a	78	10	release	release	NN
cord-262786-otxpc46a	78	11	of	of	IN
cord-262786-otxpc46a	78	12	interferons	interferon	NNS
cord-262786-otxpc46a	78	13	,	,	,
cord-262786-otxpc46a	78	14	tumor	tumor	NN
cord-262786-otxpc46a	78	15	necrosis	necrosis	NN
cord-262786-otxpc46a	78	16	factors	factor	NNS
cord-262786-otxpc46a	78	17	,	,	,
cord-262786-otxpc46a	78	18	chemokines	chemokine	NNS
cord-262786-otxpc46a	78	19	,	,	,
cord-262786-otxpc46a	78	20	interleukins	interleukin	NNS
cord-262786-otxpc46a	78	21	,	,	,
cord-262786-otxpc46a	78	22	and	and	CC
cord-262786-otxpc46a	78	23	other	other	JJ
cord-262786-otxpc46a	78	24	mediators	mediator	NNS
cord-262786-otxpc46a	78	25	in	in	IN
cord-262786-otxpc46a	78	26	a	a	DT
cord-262786-otxpc46a	78	27	hyperactive	hyperactive	JJ
cord-262786-otxpc46a	78	28	and	and	CC
cord-262786-otxpc46a	78	29	injurious	injurious	JJ
cord-262786-otxpc46a	78	30	manner	manner	NN
cord-262786-otxpc46a	78	31	against	against	IN
cord-262786-otxpc46a	78	32	host	host	NN
cord-262786-otxpc46a	78	33	tissues	tissue	NNS
cord-262786-otxpc46a	78	34	[	[	-LRB-
cord-262786-otxpc46a	78	35	36	36	CD
cord-262786-otxpc46a	78	36	]	]	-RRB-
cord-262786-otxpc46a	78	37	.	.	.
cord-262786-otxpc46a	79	1	Cytokine	cytokine	NN
cord-262786-otxpc46a	79	2	storm	storm	NN
cord-262786-otxpc46a	79	3	is	be	VBZ
cord-262786-otxpc46a	79	4	attributed	attribute	VBN
cord-262786-otxpc46a	79	5	to	to	IN
cord-262786-otxpc46a	79	6	SARS	SARS	NNP
cord-262786-otxpc46a	79	7	-	-	HYPH
cord-262786-otxpc46a	79	8	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	79	9	as	as	RB
cord-262786-otxpc46a	79	10	well	well	RB
cord-262786-otxpc46a	79	11	as	as	IN
cord-262786-otxpc46a	79	12	SARS	SARS	NNP
cord-262786-otxpc46a	79	13	-	-	HYPH
cord-262786-otxpc46a	79	14	CoV	CoV	NNP
cord-262786-otxpc46a	79	15	infection	infection	NN
cord-262786-otxpc46a	79	16	and	and	CC
cord-262786-otxpc46a	79	17	accompany	accompany	VB
cord-262786-otxpc46a	79	18	with	with	IN
cord-262786-otxpc46a	79	19	a	a	DT
cord-262786-otxpc46a	79	20	spectrum	spectrum	NN
cord-262786-otxpc46a	79	21	of	of	IN
cord-262786-otxpc46a	79	22	SIRS	SIRS	NNP
cord-262786-otxpc46a	79	23	manifestations	manifestation	NNS
cord-262786-otxpc46a	79	24	,	,	,
cord-262786-otxpc46a	79	25	including	include	VBG
cord-262786-otxpc46a	79	26	hypotension	hypotension	NN
cord-262786-otxpc46a	79	27	,	,	,
cord-262786-otxpc46a	79	28	tachycardia	tachycardia	NN
cord-262786-otxpc46a	79	29	,	,	,
cord-262786-otxpc46a	79	30	tachypnea	tachypnea	NNP
cord-262786-otxpc46a	79	31	,	,	,
cord-262786-otxpc46a	79	32	and	and	CC
cord-262786-otxpc46a	79	33	fever	fever	NN
cord-262786-otxpc46a	79	34	,	,	,
cord-262786-otxpc46a	79	35	leading	lead	VBG
cord-262786-otxpc46a	79	36	to	to	IN
cord-262786-otxpc46a	79	37	adverse	adverse	JJ
cord-262786-otxpc46a	79	38	clinical	clinical	JJ
cord-262786-otxpc46a	79	39	outcomes	outcome	NNS
cord-262786-otxpc46a	79	40	[	[	-LRB-
cord-262786-otxpc46a	79	41	36	36	CD
cord-262786-otxpc46a	79	42	]	]	-RRB-
cord-262786-otxpc46a	79	43	.	.	.
cord-262786-otxpc46a	80	1	Cytokine	cytokine	NN
cord-262786-otxpc46a	80	2	storm	storm	NN
cord-262786-otxpc46a	80	3	involves	involve	VBZ
cord-262786-otxpc46a	80	4	the	the	DT
cord-262786-otxpc46a	80	5	CNS	CNS	NNP
cord-262786-otxpc46a	80	6	,	,	,
cord-262786-otxpc46a	80	7	regarding	regard	VBG
cord-262786-otxpc46a	80	8	the	the	DT
cord-262786-otxpc46a	80	9	fact	fact	NN
cord-262786-otxpc46a	80	10	that	that	IN
cord-262786-otxpc46a	80	11	most	most	JJS
cord-262786-otxpc46a	80	12	cytokines	cytokine	NNS
cord-262786-otxpc46a	80	13	are	be	VBP
cord-262786-otxpc46a	80	14	either	either	RB
cord-262786-otxpc46a	80	15	produced	produce	VBN
cord-262786-otxpc46a	80	16	in	in	IN
cord-262786-otxpc46a	80	17	the	the	DT
cord-262786-otxpc46a	80	18	brain	brain	NN
cord-262786-otxpc46a	80	19	tissue	tissue	NN
cord-262786-otxpc46a	80	20	or	or	CC
cord-262786-otxpc46a	80	21	able	able	JJ
cord-262786-otxpc46a	80	22	to	to	TO
cord-262786-otxpc46a	80	23	cross	cross	VB
cord-262786-otxpc46a	80	24	the	the	DT
cord-262786-otxpc46a	80	25	blood	blood	NN
cord-262786-otxpc46a	80	26	-	-	HYPH
cord-262786-otxpc46a	80	27	brain	brain	NN
cord-262786-otxpc46a	80	28	barrier	barrier	NN
cord-262786-otxpc46a	80	29	in	in	IN
cord-262786-otxpc46a	80	30	the	the	DT
cord-262786-otxpc46a	80	31	condition	condition	NN
cord-262786-otxpc46a	80	32	that	that	WDT
cord-262786-otxpc46a	80	33	released	release	VBD
cord-262786-otxpc46a	80	34	cytokines	cytokine	NNS
cord-262786-otxpc46a	80	35	(	(	-LRB-
cord-262786-otxpc46a	80	36	namely	namely	RB
cord-262786-otxpc46a	80	37	,	,	,
cord-262786-otxpc46a	80	38	IL-1β	IL-1β	NNP
cord-262786-otxpc46a	80	39	,	,	,
cord-262786-otxpc46a	80	40	IL-6	IL-6	NNP
cord-262786-otxpc46a	80	41	,	,	,
cord-262786-otxpc46a	80	42	and	and	CC
cord-262786-otxpc46a	80	43	TNF	TNF	NNP
cord-262786-otxpc46a	80	44	-	-	HYPH
cord-262786-otxpc46a	80	45	α	α	NNP
cord-262786-otxpc46a	80	46	)	)	-RRB-
cord-262786-otxpc46a	80	47	disrupt	disrupt	VB
cord-262786-otxpc46a	80	48	the	the	DT
cord-262786-otxpc46a	80	49	integrity	integrity	NN
cord-262786-otxpc46a	80	50	of	of	IN
cord-262786-otxpc46a	80	51	blood	blood	NN
cord-262786-otxpc46a	80	52	-	-	HYPH
cord-262786-otxpc46a	80	53	brain	brain	NN
cord-262786-otxpc46a	80	54	barrier	barrier	NN
cord-262786-otxpc46a	80	55	[	[	-LRB-
cord-262786-otxpc46a	80	56	37	37	CD
cord-262786-otxpc46a	80	57	]	]	-RRB-
cord-262786-otxpc46a	80	58	.	.	.
cord-262786-otxpc46a	81	1	So	so	RB
cord-262786-otxpc46a	81	2	,	,	,
cord-262786-otxpc46a	81	3	brain	brain	NN
cord-262786-otxpc46a	81	4	autopsy	autopsy	JJ
cord-262786-otxpc46a	81	5	studies	study	NNS
cord-262786-otxpc46a	81	6	of	of	IN
cord-262786-otxpc46a	81	7	postmortem	postmortem	JJ
cord-262786-otxpc46a	81	8	SARS	SARS	NNP
cord-262786-otxpc46a	81	9	-	-	HYPH
cord-262786-otxpc46a	81	10	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	81	11	patients	patient	NNS
cord-262786-otxpc46a	81	12	demonstrate	demonstrate	VBP
cord-262786-otxpc46a	81	13	the	the	DT
cord-262786-otxpc46a	81	14	infiltration	infiltration	NN
cord-262786-otxpc46a	81	15	of	of	IN
cord-262786-otxpc46a	81	16	monocytes	monocyte	NNS
cord-262786-otxpc46a	81	17	,	,	,
cord-262786-otxpc46a	81	18	macrophages	macrophage	NNS
cord-262786-otxpc46a	81	19	,	,	,
cord-262786-otxpc46a	81	20	and	and	CC
cord-262786-otxpc46a	81	21	T	t	NN
cord-262786-otxpc46a	81	22	-	-	HYPH
cord-262786-otxpc46a	81	23	lymphocytes	lymphocyte	NNS
cord-262786-otxpc46a	81	24	into	into	IN
cord-262786-otxpc46a	81	25	the	the	DT
cord-262786-otxpc46a	81	26	vessel	vessel	NN
cord-262786-otxpc46a	81	27	walls	wall	NNS
cord-262786-otxpc46a	81	28	(	(	-LRB-
cord-262786-otxpc46a	81	29	Fig	fig	NN
cord-262786-otxpc46a	81	30	.	.	NNP
cord-262786-otxpc46a	81	31	2	2	CD
cord-262786-otxpc46a	81	32	)	)	-RRB-
cord-262786-otxpc46a	82	1	[	[	-LRB-
cord-262786-otxpc46a	82	2	15	15	CD
cord-262786-otxpc46a	82	3	]	]	-RRB-
cord-262786-otxpc46a	82	4	.	.	.
cord-262786-otxpc46a	83	1	Also	also	RB
cord-262786-otxpc46a	83	2	,	,	,
cord-262786-otxpc46a	83	3	interferon	interferon	NN
cord-262786-otxpc46a	83	4	-	-	:
cord-262786-otxpc46a	83	5	α2	α2	NNP
cord-262786-otxpc46a	83	6	(	(	-LRB-
cord-262786-otxpc46a	83	7	IFN	IFN	NNP
cord-262786-otxpc46a	83	8	-	-	HYPH
cord-262786-otxpc46a	83	9	α2	α2	NNP
cord-262786-otxpc46a	83	10	)	)	-RRB-
cord-262786-otxpc46a	83	11	and	and	CC
cord-262786-otxpc46a	83	12	IFN	IFN	NNP
cord-262786-otxpc46a	83	13	-	-	HYPH
cord-262786-otxpc46a	83	14	γ	γ	NNP
cord-262786-otxpc46a	83	15	upregulate	upregulate	VBP
cord-262786-otxpc46a	83	16	the	the	DT
cord-262786-otxpc46a	83	17	expression	expression	NN
cord-262786-otxpc46a	83	18	of	of	IN
cord-262786-otxpc46a	83	19	ACE-2	ACE-2	NNP
cord-262786-otxpc46a	83	20	receptors	receptor	NNS
cord-262786-otxpc46a	83	21	and	and	CC
cord-262786-otxpc46a	83	22	,	,	,
cord-262786-otxpc46a	83	23	thus	thus	RB
cord-262786-otxpc46a	83	24	,	,	,
cord-262786-otxpc46a	83	25	facilitate	facilitate	VB
cord-262786-otxpc46a	83	26	the	the	DT
cord-262786-otxpc46a	83	27	entry	entry	NN
cord-262786-otxpc46a	83	28	of	of	IN
cord-262786-otxpc46a	83	29	the	the	DT
cord-262786-otxpc46a	83	30	virus	virus	NN
cord-262786-otxpc46a	83	31	into	into	IN
cord-262786-otxpc46a	83	32	host	host	NN
cord-262786-otxpc46a	83	33	cells	cell	NNS
cord-262786-otxpc46a	83	34	in	in	IN
cord-262786-otxpc46a	83	35	-	-	HYPH
cord-262786-otxpc46a	83	36	vitro	vitro	FW
cord-262786-otxpc46a	83	37	[	[	-LRB-
cord-262786-otxpc46a	83	38	38	38	CD
cord-262786-otxpc46a	83	39	]	]	-RRB-
cord-262786-otxpc46a	83	40	.	.	.
cord-262786-otxpc46a	84	1	Cytokine	cytokine	NN
cord-262786-otxpc46a	84	2	storm	storm	NN
cord-262786-otxpc46a	84	3	results	result	VBZ
cord-262786-otxpc46a	84	4	in	in	IN
cord-262786-otxpc46a	84	5	neural	neural	JJ
cord-262786-otxpc46a	84	6	death	death	NN
cord-262786-otxpc46a	84	7	,	,	,
cord-262786-otxpc46a	84	8	activation	activation	NN
cord-262786-otxpc46a	84	9	of	of	IN
cord-262786-otxpc46a	84	10	microglia	microglia	NN
cord-262786-otxpc46a	84	11	,	,	,
cord-262786-otxpc46a	84	12	disruption	disruption	NN
cord-262786-otxpc46a	84	13	of	of	IN
cord-262786-otxpc46a	84	14	synaptic	synaptic	JJ
cord-262786-otxpc46a	84	15	plasticity	plasticity	NN
cord-262786-otxpc46a	84	16	,	,	,
cord-262786-otxpc46a	84	17	and	and	CC
cord-262786-otxpc46a	84	18	impairment	impairment	NN
cord-262786-otxpc46a	84	19	in	in	IN
cord-262786-otxpc46a	84	20	neurotransmitter	neurotransmitter	NN
cord-262786-otxpc46a	84	21	metabolism	metabolism	NN
cord-262786-otxpc46a	84	22	.	.	.
cord-262786-otxpc46a	85	1	Cytokine	cytokine	NN
cord-262786-otxpc46a	85	2	storm	storm	NN
cord-262786-otxpc46a	85	3	is	be	VBZ
cord-262786-otxpc46a	85	4	also	also	RB
cord-262786-otxpc46a	85	5	a	a	DT
cord-262786-otxpc46a	85	6	predictor	predictor	NN
cord-262786-otxpc46a	85	7	of	of	IN
cord-262786-otxpc46a	85	8	hippocampal	hippocampal	JJ
cord-262786-otxpc46a	85	9	atrophy	atrophy	NN
cord-262786-otxpc46a	85	10	[	[	-LRB-
cord-262786-otxpc46a	85	11	12	12	CD
cord-262786-otxpc46a	85	12	]	]	-RRB-
cord-262786-otxpc46a	85	13	.	.	.
cord-262786-otxpc46a	86	1	Cytokine	cytokine	NN
cord-262786-otxpc46a	86	2	storm	storm	NN
cord-262786-otxpc46a	86	3	stimulates	stimulate	VBZ
cord-262786-otxpc46a	86	4	the	the	DT
cord-262786-otxpc46a	86	5	secretion	secretion	NN
cord-262786-otxpc46a	86	6	of	of	IN
cord-262786-otxpc46a	86	7	glucocorticoids	glucocorticoid	NNS
cord-262786-otxpc46a	86	8	through	through	IN
cord-262786-otxpc46a	86	9	manipulation	manipulation	NN
cord-262786-otxpc46a	86	10	of	of	IN
cord-262786-otxpc46a	86	11	the	the	DT
cord-262786-otxpc46a	86	12	hypothalamic	hypothalamic	JJ
cord-262786-otxpc46a	86	13	-	-	HYPH
cord-262786-otxpc46a	86	14	pituitary	pituitary	NN
cord-262786-otxpc46a	86	15	-	-	HYPH
cord-262786-otxpc46a	86	16	adrenocortical	adrenocortical	JJ
cord-262786-otxpc46a	86	17	axis	axis	NN
cord-262786-otxpc46a	86	18	;	;	:
cord-262786-otxpc46a	86	19	nevertheless	nevertheless	RB
cord-262786-otxpc46a	86	20	,	,	,
cord-262786-otxpc46a	86	21	the	the	DT
cord-262786-otxpc46a	86	22	resultant	resultant	JJ
cord-262786-otxpc46a	86	23	increase	increase	NN
cord-262786-otxpc46a	86	24	in	in	IN
cord-262786-otxpc46a	86	25	glucocorticoids	glucocorticoid	NNS
cord-262786-otxpc46a	86	26	is	be	VBZ
cord-262786-otxpc46a	86	27	not	not	RB
cord-262786-otxpc46a	86	28	able	able	JJ
cord-262786-otxpc46a	86	29	to	to	TO
cord-262786-otxpc46a	86	30	suppress	suppress	VB
cord-262786-otxpc46a	86	31	the	the	DT
cord-262786-otxpc46a	86	32	inflammation	inflammation	NN
cord-262786-otxpc46a	86	33	due	due	IN
cord-262786-otxpc46a	86	34	to	to	IN
cord-262786-otxpc46a	86	35	impaired	impaired	JJ
cord-262786-otxpc46a	86	36	negative	negative	JJ
cord-262786-otxpc46a	86	37	feedback	feedback	NN
cord-262786-otxpc46a	86	38	mechanism	mechanism	NN
cord-262786-otxpc46a	86	39	[	[	-LRB-
cord-262786-otxpc46a	86	40	25	25	CD
cord-262786-otxpc46a	86	41	]	]	-RRB-
cord-262786-otxpc46a	86	42	.	.	.
cord-262786-otxpc46a	87	1	Last	last	JJ
cord-262786-otxpc46a	87	2	but	but	CC
cord-262786-otxpc46a	87	3	not	not	RB
cord-262786-otxpc46a	87	4	least	least	JJS
cord-262786-otxpc46a	87	5	,	,	,
cord-262786-otxpc46a	87	6	the	the	DT
cord-262786-otxpc46a	87	7	cytokine	cytokine	NN
cord-262786-otxpc46a	87	8	storm	storm	NN
cord-262786-otxpc46a	87	9	might	may	MD
cord-262786-otxpc46a	87	10	lead	lead	VB
cord-262786-otxpc46a	87	11	to	to	IN
cord-262786-otxpc46a	87	12	delayed	delay	VBN
cord-262786-otxpc46a	87	13	immune	immune	JJ
cord-262786-otxpc46a	87	14	dysregulation	dysregulation	NN
cord-262786-otxpc46a	87	15	after	after	IN
cord-262786-otxpc46a	87	16	the	the	DT
cord-262786-otxpc46a	87	17	disease	disease	NN
cord-262786-otxpc46a	87	18	course	course	NN
cord-262786-otxpc46a	87	19	,	,	,
cord-262786-otxpc46a	87	20	manifested	manifest	VBN
cord-262786-otxpc46a	87	21	by	by	IN
cord-262786-otxpc46a	87	22	persistent	persistent	JJ
cord-262786-otxpc46a	87	23	inflammation	inflammation	NN
cord-262786-otxpc46a	87	24	or	or	CC
cord-262786-otxpc46a	87	25	immunosuppression	immunosuppression	NN
cord-262786-otxpc46a	87	26	,	,	,
cord-262786-otxpc46a	87	27	which	which	WDT
cord-262786-otxpc46a	87	28	might	may	MD
cord-262786-otxpc46a	87	29	cause	cause	VB
cord-262786-otxpc46a	87	30	delayed	delayed	JJ
cord-262786-otxpc46a	87	31	complications	complication	NNS
cord-262786-otxpc46a	87	32	[	[	-LRB-
cord-262786-otxpc46a	87	33	25	25	CD
cord-262786-otxpc46a	87	34	]	]	-RRB-
cord-262786-otxpc46a	87	35	.	.	.
cord-262786-otxpc46a	88	1	CNS	CNS	NNP
cord-262786-otxpc46a	88	2	features	feature	NNS
cord-262786-otxpc46a	88	3	of	of	IN
cord-262786-otxpc46a	88	4	SARS	SARS	NNP
cord-262786-otxpc46a	88	5	-	-	HYPH
cord-262786-otxpc46a	88	6	CoV	CoV	NNP
cord-262786-otxpc46a	88	7	,	,	,
cord-262786-otxpc46a	88	8	MERS	MERS	NNP
cord-262786-otxpc46a	88	9	-	-	HYPH
cord-262786-otxpc46a	88	10	CoV	CoV	NNP
cord-262786-otxpc46a	88	11	,	,	,
cord-262786-otxpc46a	88	12	and	and	CC
cord-262786-otxpc46a	88	13	SARS	SARS	NNP
cord-262786-otxpc46a	88	14	-	-	HYPH
cord-262786-otxpc46a	88	15	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	88	16	are	be	VBP
cord-262786-otxpc46a	88	17	summarized	summarize	VBN
cord-262786-otxpc46a	88	18	in	in	IN
cord-262786-otxpc46a	88	19	Table	Table	NNP
cord-262786-otxpc46a	88	20	1	1	CD
cord-262786-otxpc46a	88	21	.	.	.
cord-262786-otxpc46a	89	1	Regarding	regard	VBG
cord-262786-otxpc46a	89	2	the	the	DT
cord-262786-otxpc46a	89	3	widespread	widespread	JJ
cord-262786-otxpc46a	89	4	influence	influence	NN
cord-262786-otxpc46a	89	5	of	of	IN
cord-262786-otxpc46a	89	6	SARS	SARS	NNP
cord-262786-otxpc46a	89	7	-	-	HYPH
cord-262786-otxpc46a	89	8	CoV-2mediated	cov-2mediate	VBN
cord-262786-otxpc46a	89	9	immune	immune	JJ
cord-262786-otxpc46a	89	10	response	response	NN
cord-262786-otxpc46a	89	11	on	on	IN
cord-262786-otxpc46a	89	12	CNS	CNS	NNP
cord-262786-otxpc46a	89	13	,	,	,
cord-262786-otxpc46a	89	14	we	-PRON-	PRP
cord-262786-otxpc46a	89	15	discuss	discuss	VBP
cord-262786-otxpc46a	89	16	the	the	DT
cord-262786-otxpc46a	89	17	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	89	18	correlates	correlate	NNS
cord-262786-otxpc46a	89	19	of	of	IN
cord-262786-otxpc46a	89	20	neurologic	neurologic	JJ
cord-262786-otxpc46a	89	21	sequelae	sequela	NNS
cord-262786-otxpc46a	89	22	of	of	IN
cord-262786-otxpc46a	89	23	SARS	SARS	NNP
cord-262786-otxpc46a	89	24	-	-	HYPH
cord-262786-otxpc46a	89	25	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	89	26	in	in	IN
cord-262786-otxpc46a	89	27	the	the	DT
cord-262786-otxpc46a	89	28	following	follow	VBG
cord-262786-otxpc46a	89	29	sections	section	NNS
cord-262786-otxpc46a	89	30	.	.	.
cord-262786-otxpc46a	89	31	 	 	_SP
cord-262786-otxpc46a	90	1	Brain	brain	NN
cord-262786-otxpc46a	90	2	areas	area	NNS
cord-262786-otxpc46a	90	3	like	like	IN
cord-262786-otxpc46a	90	4	the	the	DT
cord-262786-otxpc46a	90	5	hippocampus	hippocampus	NN
cord-262786-otxpc46a	90	6	and	and	CC
cord-262786-otxpc46a	90	7	midbrain	midbrain	NN
cord-262786-otxpc46a	90	8	are	be	VBP
cord-262786-otxpc46a	90	9	vulnerable	vulnerable	JJ
cord-262786-otxpc46a	90	10	to	to	IN
cord-262786-otxpc46a	90	11	direct	direct	JJ
cord-262786-otxpc46a	90	12	SARS	SARS	NNP
cord-262786-otxpc46a	90	13	-	-	HYPH
cord-262786-otxpc46a	90	14	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	90	15	invasion	invasion	NN
cord-262786-otxpc46a	90	16	and	and	CC
cord-262786-otxpc46a	90	17	induction	induction	NN
cord-262786-otxpc46a	90	18	of	of	IN
cord-262786-otxpc46a	90	19	Alzheimer	Alzheimer	NNP
cord-262786-otxpc46a	90	20	's	's	POS
cord-262786-otxpc46a	90	21	disease	disease	NN
cord-262786-otxpc46a	90	22	(	(	-LRB-
cord-262786-otxpc46a	90	23	AD	ad	NN
cord-262786-otxpc46a	90	24	)	)	-RRB-
cord-262786-otxpc46a	90	25	and	and	CC
cord-262786-otxpc46a	90	26	Parkinson	Parkinson	NNP
cord-262786-otxpc46a	90	27	's	's	POS
cord-262786-otxpc46a	90	28	disease	disease	NN
cord-262786-otxpc46a	90	29	(	(	-LRB-
cord-262786-otxpc46a	90	30	PD	PD	NNP
cord-262786-otxpc46a	90	31	)	)	-RRB-
cord-262786-otxpc46a	90	32	,	,	,
cord-262786-otxpc46a	90	33	respectively	respectively	RB
cord-262786-otxpc46a	90	34	[	[	-LRB-
cord-262786-otxpc46a	90	35	18	18	CD
cord-262786-otxpc46a	90	36	]	]	-RRB-
cord-262786-otxpc46a	90	37	.	.	.
cord-262786-otxpc46a	91	1	The	the	DT
cord-262786-otxpc46a	91	2	aberrant	aberrant	JJ
cord-262786-otxpc46a	91	3	immune	immune	JJ
cord-262786-otxpc46a	91	4	response	response	NN
cord-262786-otxpc46a	91	5	characterized	characterize	VBN
cord-262786-otxpc46a	91	6	by	by	IN
cord-262786-otxpc46a	91	7	a	a	DT
cord-262786-otxpc46a	91	8	surge	surge	NN
cord-262786-otxpc46a	91	9	in	in	IN
cord-262786-otxpc46a	91	10	cytokine	cytokine	NN
cord-262786-otxpc46a	91	11	levels	level	NNS
cord-262786-otxpc46a	91	12	(	(	-LRB-
cord-262786-otxpc46a	91	13	e.g.	e.g.	RB
cord-262786-otxpc46a	91	14	,	,	,
cord-262786-otxpc46a	91	15	IL-6	IL-6	NNP
cord-262786-otxpc46a	91	16	)	)	-RRB-
cord-262786-otxpc46a	91	17	derived	derive	VBN
cord-262786-otxpc46a	91	18	by	by	IN
cord-262786-otxpc46a	91	19	SARS	SARS	NNP
cord-262786-otxpc46a	91	20	-	-	HYPH
cord-262786-otxpc46a	91	21	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	91	22	accelerates	accelerate	VBZ
cord-262786-otxpc46a	91	23	the	the	DT
cord-262786-otxpc46a	91	24	process	process	NN
cord-262786-otxpc46a	91	25	of	of	IN
cord-262786-otxpc46a	91	26	neurodegeneration	neurodegeneration	NN
cord-262786-otxpc46a	91	27	that	that	WDT
cord-262786-otxpc46a	91	28	may	may	MD
cord-262786-otxpc46a	91	29	contribute	contribute	VB
cord-262786-otxpc46a	91	30	to	to	IN
cord-262786-otxpc46a	91	31	the	the	DT
cord-262786-otxpc46a	91	32	development	development	NN
cord-262786-otxpc46a	91	33	of	of	IN
cord-262786-otxpc46a	91	34	neurodegenerative	neurodegenerative	JJ
cord-262786-otxpc46a	91	35	diseases	disease	NNS
cord-262786-otxpc46a	91	36	[	[	-LRB-
cord-262786-otxpc46a	91	37	42	42	CD
cord-262786-otxpc46a	91	38	]	]	-RRB-
cord-262786-otxpc46a	91	39	.	.	.
cord-262786-otxpc46a	92	1	The	the	DT
cord-262786-otxpc46a	92	2	mentioned	mention	VBN
cord-262786-otxpc46a	92	3	aberrant	aberrant	JJ
cord-262786-otxpc46a	92	4	immune	immune	JJ
cord-262786-otxpc46a	92	5	response	response	NN
cord-262786-otxpc46a	92	6	may	may	MD
cord-262786-otxpc46a	92	7	be	be	VB
cord-262786-otxpc46a	92	8	a	a	DT
cord-262786-otxpc46a	92	9	consequence	consequence	NN
cord-262786-otxpc46a	92	10	of	of	IN
cord-262786-otxpc46a	92	11	infection	infection	NN
cord-262786-otxpc46a	92	12	of	of	IN
cord-262786-otxpc46a	92	13	intestinal	intestinal	JJ
cord-262786-otxpc46a	92	14	mucosa	mucosa	NN
cord-262786-otxpc46a	92	15	and	and	CC
cord-262786-otxpc46a	92	16	modulation	modulation	NN
cord-262786-otxpc46a	92	17	of	of	IN
cord-262786-otxpc46a	92	18	the	the	DT
cord-262786-otxpc46a	92	19	gut	gut	NN
cord-262786-otxpc46a	92	20	microbiome	microbiome	NN
cord-262786-otxpc46a	92	21	by	by	IN
cord-262786-otxpc46a	92	22	SARS	SARS	NNP
cord-262786-otxpc46a	92	23	-	-	HYPH
cord-262786-otxpc46a	92	24	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	92	25	,	,	,
cord-262786-otxpc46a	92	26	which	which	WDT
cord-262786-otxpc46a	92	27	can	can	MD
cord-262786-otxpc46a	92	28	trigger	trigger	VB
cord-262786-otxpc46a	92	29	neuroinflammation	neuroinflammation	NN
cord-262786-otxpc46a	92	30	and	and	CC
cord-262786-otxpc46a	92	31	neurodegeneration	neurodegeneration	NN
cord-262786-otxpc46a	92	32	[	[	-LRB-
cord-262786-otxpc46a	92	33	24	24	CD
cord-262786-otxpc46a	92	34	]	]	-RRB-
cord-262786-otxpc46a	92	35	.	.	.
cord-262786-otxpc46a	93	1	Interestingly	interestingly	RB
cord-262786-otxpc46a	93	2	,	,	,
cord-262786-otxpc46a	93	3	modulation	modulation	NN
cord-262786-otxpc46a	93	4	of	of	IN
cord-262786-otxpc46a	93	5	the	the	DT
cord-262786-otxpc46a	93	6	gut	gut	NN
cord-262786-otxpc46a	93	7	microbiome	microbiome	NN
cord-262786-otxpc46a	93	8	plays	play	VBZ
cord-262786-otxpc46a	93	9	a	a	DT
cord-262786-otxpc46a	93	10	role	role	NN
cord-262786-otxpc46a	93	11	in	in	IN
cord-262786-otxpc46a	93	12	the	the	DT
cord-262786-otxpc46a	93	13	pathophysiology	pathophysiology	NN
cord-262786-otxpc46a	93	14	of	of	IN
cord-262786-otxpc46a	93	15	AD	ad	NN
cord-262786-otxpc46a	93	16	and	and	CC
cord-262786-otxpc46a	93	17	PD	PD	NNP
cord-262786-otxpc46a	93	18	[	[	-LRB-
cord-262786-otxpc46a	93	19	43	43	CD
cord-262786-otxpc46a	93	20	,	,	,
cord-262786-otxpc46a	93	21	44	44	CD
cord-262786-otxpc46a	93	22	]	]	-RRB-
cord-262786-otxpc46a	93	23	.	.	.
cord-262786-otxpc46a	94	1	Seemingly	seemingly	RB
cord-262786-otxpc46a	94	2	,	,	,
cord-262786-otxpc46a	94	3	other	other	JJ
cord-262786-otxpc46a	94	4	coronaviruses	coronaviruse	NNS
cord-262786-otxpc46a	94	5	like	like	IN
cord-262786-otxpc46a	94	6	human	human	JJ
cord-262786-otxpc46a	94	7	coronavirus	coronavirus	NN
cord-262786-otxpc46a	94	8	OC43	OC43	NNP
cord-262786-otxpc46a	94	9	(	(	-LRB-
cord-262786-otxpc46a	94	10	HCV	HCV	NNP
cord-262786-otxpc46a	94	11	-	-	HYPH
cord-262786-otxpc46a	94	12	OC43	OC43	NNP
cord-262786-otxpc46a	94	13	)	)	-RRB-
cord-262786-otxpc46a	94	14	may	may	MD
cord-262786-otxpc46a	94	15	trigger	trigger	VB
cord-262786-otxpc46a	94	16	delayed	delay	VBN
cord-262786-otxpc46a	94	17	neural	neural	JJ
cord-262786-otxpc46a	94	18	degeneration	degeneration	NN
cord-262786-otxpc46a	94	19	in	in	IN
cord-262786-otxpc46a	94	20	animal	animal	NN
cord-262786-otxpc46a	94	21	models	model	NNS
cord-262786-otxpc46a	94	22	[	[	-LRB-
cord-262786-otxpc46a	94	23	45	45	CD
cord-262786-otxpc46a	94	24	]	]	-RRB-
cord-262786-otxpc46a	94	25	.	.	.
cord-262786-otxpc46a	95	1	Alzheimer	Alzheimer	NNP
cord-262786-otxpc46a	95	2	's	's	POS
cord-262786-otxpc46a	95	3	Disease	Disease	NNP
cord-262786-otxpc46a	95	4	AD	AD	NNP
cord-262786-otxpc46a	95	5	,	,	,
cord-262786-otxpc46a	95	6	the	the	DT
cord-262786-otxpc46a	95	7	most	most	RBS
cord-262786-otxpc46a	95	8	prevalent	prevalent	JJ
cord-262786-otxpc46a	95	9	neurodegenerative	neurodegenerative	JJ
cord-262786-otxpc46a	95	10	disorder	disorder	NN
cord-262786-otxpc46a	95	11	,	,	,
cord-262786-otxpc46a	95	12	is	be	VBZ
cord-262786-otxpc46a	95	13	characterized	characterize	VBN
cord-262786-otxpc46a	95	14	by	by	IN
cord-262786-otxpc46a	95	15	the	the	DT
cord-262786-otxpc46a	95	16	accumulation	accumulation	NN
cord-262786-otxpc46a	95	17	of	of	IN
cord-262786-otxpc46a	95	18	intraneuronal	intraneuronal	JJ
cord-262786-otxpc46a	95	19	aggregates	aggregate	NNS
cord-262786-otxpc46a	95	20	of	of	IN
cord-262786-otxpc46a	95	21	hyperphosphorylated	hyperphosphorylated	NNP
cord-262786-otxpc46a	95	22	tau	tau	NNP
cord-262786-otxpc46a	95	23	and	and	CC
cord-262786-otxpc46a	95	24	extracellular	extracellular	JJ
cord-262786-otxpc46a	95	25	beta	beta	NN
cord-262786-otxpc46a	95	26	-	-	HYPH
cord-262786-otxpc46a	95	27	amyloid	amyloid	NN
cord-262786-otxpc46a	95	28	plaques	plaque	NNS
cord-262786-otxpc46a	95	29	[	[	-LRB-
cord-262786-otxpc46a	95	30	37	37	CD
cord-262786-otxpc46a	95	31	,	,	,
cord-262786-otxpc46a	95	32	46	46	CD
cord-262786-otxpc46a	95	33	,	,	,
cord-262786-otxpc46a	95	34	47	47	CD
cord-262786-otxpc46a	95	35	]	]	-RRB-
cord-262786-otxpc46a	95	36	.	.	.
cord-262786-otxpc46a	96	1	Considering	consider	VBG
cord-262786-otxpc46a	96	2	the	the	DT
cord-262786-otxpc46a	96	3	role	role	NN
cord-262786-otxpc46a	96	4	of	of	IN
cord-262786-otxpc46a	96	5	cholesterolbinding	cholesterolbinde	VBG
cord-262786-otxpc46a	96	6	protein	protein	NN
cord-262786-otxpc46a	96	7	(	(	-LRB-
cord-262786-otxpc46a	96	8	Apolipoprotein	Apolipoprotein	NNP
cord-262786-otxpc46a	96	9	E	E	NNP
cord-262786-otxpc46a	96	10	(	(	-LRB-
cord-262786-otxpc46a	96	11	ApoE	ApoE	NNP
cord-262786-otxpc46a	96	12	)	)	-RRB-
cord-262786-otxpc46a	96	13	)	)	-RRB-
cord-262786-otxpc46a	96	14	,	,	,
cord-262786-otxpc46a	96	15	a	a	DT
cord-262786-otxpc46a	96	16	potential	potential	JJ
cord-262786-otxpc46a	96	17	link	link	NN
cord-262786-otxpc46a	96	18	between	between	IN
cord-262786-otxpc46a	96	19	AD	ad	NN
cord-262786-otxpc46a	96	20	and	and	CC
cord-262786-otxpc46a	96	21	SARS	SARS	NNP
cord-262786-otxpc46a	96	22	-	-	HYPH
cord-262786-otxpc46a	96	23	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	96	24	infection	infection	NN
cord-262786-otxpc46a	96	25	is	be	VBZ
cord-262786-otxpc46a	96	26	implicated	implicate	VBN
cord-262786-otxpc46a	96	27	.	.	.
cord-262786-otxpc46a	97	1	Serum	serum	NN
cord-262786-otxpc46a	97	2	cholesterols	cholesterol	NNS
cord-262786-otxpc46a	97	3	bind	bind	VBP
cord-262786-otxpc46a	97	4	to	to	IN
cord-262786-otxpc46a	97	5	ApoE	ApoE	NNS
cord-262786-otxpc46a	97	6	receptors	receptor	NNS
cord-262786-otxpc46a	97	7	and	and	CC
cord-262786-otxpc46a	97	8	induce	induce	VB
cord-262786-otxpc46a	97	9	ACE-2	ACE-2	NNP
cord-262786-otxpc46a	97	10	receptor	receptor	NN
cord-262786-otxpc46a	97	11	transport	transport	NN
cord-262786-otxpc46a	97	12	to	to	IN
cord-262786-otxpc46a	97	13	the	the	DT
cord-262786-otxpc46a	97	14	cell	cell	NN
cord-262786-otxpc46a	97	15	surface	surface	NN
cord-262786-otxpc46a	97	16	[	[	-LRB-
cord-262786-otxpc46a	97	17	48	48	CD
cord-262786-otxpc46a	97	18	]	]	-RRB-
cord-262786-otxpc46a	97	19	.	.	.
cord-262786-otxpc46a	98	1	Super	super	JJ
cord-262786-otxpc46a	98	2	-	-	NN
cord-262786-otxpc46a	98	3	resolution	resolution	JJ
cord-262786-otxpc46a	98	4	imaging	imaging	NN
cord-262786-otxpc46a	98	5	study	study	NN
cord-262786-otxpc46a	98	6	demonstrates	demonstrate	VBZ
cord-262786-otxpc46a	98	7	that	that	IN
cord-262786-otxpc46a	98	8	high	high	JJ
cord-262786-otxpc46a	98	9	cholesterol	cholesterol	NN
cord-262786-otxpc46a	98	10	levels	level	NNS
cord-262786-otxpc46a	98	11	confer	confer	VBP
cord-262786-otxpc46a	98	12	a	a	DT
cord-262786-otxpc46a	98	13	2-fold	2-fold	CD
cord-262786-otxpc46a	98	14	increase	increase	NN
cord-262786-otxpc46a	98	15	in	in	IN
cord-262786-otxpc46a	98	16	SARS	SARS	NNP
cord-262786-otxpc46a	98	17	-	-	HYPH
cord-262786-otxpc46a	98	18	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	98	19	entry	entry	NN
cord-262786-otxpc46a	98	20	sites	site	NNS
cord-262786-otxpc46a	98	21	and	and	CC
cord-262786-otxpc46a	98	22	thus	thus	RB
cord-262786-otxpc46a	98	23	facilitate	facilitate	VB
cord-262786-otxpc46a	98	24	the	the	DT
cord-262786-otxpc46a	98	25	viral	viral	JJ
cord-262786-otxpc46a	98	26	entry	entry	NN
cord-262786-otxpc46a	98	27	[	[	-LRB-
cord-262786-otxpc46a	98	28	48	48	CD
cord-262786-otxpc46a	98	29	]	]	-RRB-
cord-262786-otxpc46a	98	30	.	.	.
cord-262786-otxpc46a	99	1	ApoE	ApoE	NNP
cord-262786-otxpc46a	99	2	and	and	CC
cord-262786-otxpc46a	99	3	ACE-2	ACE-2	NNP
cord-262786-otxpc46a	99	4	are	be	VBP
cord-262786-otxpc46a	99	5	highly	highly	RB
cord-262786-otxpc46a	99	6	expressed	express	VBN
cord-262786-otxpc46a	99	7	in	in	IN
cord-262786-otxpc46a	99	8	alveolar	alveolar	JJ
cord-262786-otxpc46a	99	9	type	type	NN
cord-262786-otxpc46a	99	10	II	ii	CD
cord-262786-otxpc46a	99	11	cells	cell	NNS
cord-262786-otxpc46a	99	12	,	,	,
cord-262786-otxpc46a	99	13	and	and	CC
cord-262786-otxpc46a	99	14	the	the	DT
cord-262786-otxpc46a	99	15	ApoE	ApoE	NNPS
cord-262786-otxpc46a	99	16	e4	e4	NNP
cord-262786-otxpc46a	99	17	allele	allele	NN
cord-262786-otxpc46a	99	18	modulates	modulate	VBZ
cord-262786-otxpc46a	99	19	the	the	DT
cord-262786-otxpc46a	99	20	pro-/anti	pro-/anti	JJ
cord-262786-otxpc46a	99	21	-	-	HYPH
cord-262786-otxpc46a	99	22	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	99	23	state	state	NN
cord-262786-otxpc46a	99	24	in	in	IN
cord-262786-otxpc46a	99	25	macrophages	macrophage	NNS
cord-262786-otxpc46a	99	26	[	[	-LRB-
cord-262786-otxpc46a	99	27	49	49	CD
cord-262786-otxpc46a	99	28	]	]	-RRB-
cord-262786-otxpc46a	99	29	.	.	.
cord-262786-otxpc46a	100	1	On	on	IN
cord-262786-otxpc46a	100	2	the	the	DT
cord-262786-otxpc46a	100	3	other	other	JJ
cord-262786-otxpc46a	100	4	hand	hand	NN
cord-262786-otxpc46a	100	5	,	,	,
cord-262786-otxpc46a	100	6	ApoE	ApoE	NNPS
cord-262786-otxpc46a	100	7	,	,	,
cord-262786-otxpc46a	100	8	acting	act	VBG
cord-262786-otxpc46a	100	9	in	in	IN
cord-262786-otxpc46a	100	10	conjunction	conjunction	NN
cord-262786-otxpc46a	100	11	with	with	IN
cord-262786-otxpc46a	100	12	APOC1	APOC1	NNP
cord-262786-otxpc46a	100	13	and	and	CC
cord-262786-otxpc46a	100	14	APOJ	APOJ	NNP
cord-262786-otxpc46a	100	15	,	,	,
cord-262786-otxpc46a	100	16	transports	transport	VBZ
cord-262786-otxpc46a	100	17	cholesterol	cholesterol	NN
cord-262786-otxpc46a	100	18	to	to	TO
cord-262786-otxpc46a	100	19	maintain	maintain	VB
cord-262786-otxpc46a	100	20	the	the	DT
cord-262786-otxpc46a	100	21	myelin	myelin	NN
cord-262786-otxpc46a	100	22	and	and	CC
cord-262786-otxpc46a	100	23	neural	neural	JJ
cord-262786-otxpc46a	100	24	membranes	membrane	NNS
cord-262786-otxpc46a	100	25	,	,	,
cord-262786-otxpc46a	100	26	dendritic	dendritic	JJ
cord-262786-otxpc46a	100	27	reorganization	reorganization	NN
cord-262786-otxpc46a	100	28	,	,	,
cord-262786-otxpc46a	100	29	and	and	CC
cord-262786-otxpc46a	100	30	synaptic	synaptic	JJ
cord-262786-otxpc46a	100	31	turnover	turnover	NN
cord-262786-otxpc46a	100	32	[	[	-LRB-
cord-262786-otxpc46a	100	33	50	50	CD
cord-262786-otxpc46a	100	34	]	]	-RRB-
cord-262786-otxpc46a	100	35	.	.	.
cord-262786-otxpc46a	101	1	ApoE	ApoE	NNP
cord-262786-otxpc46a	101	2	functions	function	NNS
cord-262786-otxpc46a	101	3	as	as	IN
cord-262786-otxpc46a	101	4	a	a	DT
cord-262786-otxpc46a	101	5	beta	beta	JJ
cord-262786-otxpc46a	101	6	-	-	HYPH
cord-262786-otxpc46a	101	7	amyloid	amyloid	NN
cord-262786-otxpc46a	101	8	chaperone	chaperone	NN
cord-262786-otxpc46a	101	9	through	through	IN
cord-262786-otxpc46a	101	10	the	the	DT
cord-262786-otxpc46a	101	11	transport	transport	NN
cord-262786-otxpc46a	101	12	of	of	IN
cord-262786-otxpc46a	101	13	beta	beta	NN
cord-262786-otxpc46a	101	14	-	-	HYPH
cord-262786-otxpc46a	101	15	amyloids	amyloid	NNS
cord-262786-otxpc46a	101	16	to	to	IN
cord-262786-otxpc46a	101	17	the	the	DT
cord-262786-otxpc46a	101	18	lysosomes	lysosome	NNS
cord-262786-otxpc46a	101	19	[	[	-LRB-
cord-262786-otxpc46a	101	20	50	50	CD
cord-262786-otxpc46a	101	21	]	]	-RRB-
cord-262786-otxpc46a	101	22	.	.	.
cord-262786-otxpc46a	102	1	ApoE	ApoE	NNP
cord-262786-otxpc46a	102	2	e4	e4	NNP
cord-262786-otxpc46a	102	3	allele	allele	NN
cord-262786-otxpc46a	102	4	associates	associate	NNS
cord-262786-otxpc46a	102	5	with	with	IN
cord-262786-otxpc46a	102	6	increased	increase	VBN
cord-262786-otxpc46a	102	7	formation	formation	NN
cord-262786-otxpc46a	102	8	and	and	CC
cord-262786-otxpc46a	102	9	deposition	deposition	NN
cord-262786-otxpc46a	102	10	of	of	IN
cord-262786-otxpc46a	102	11	beta	beta	NN
cord-262786-otxpc46a	102	12	-	-	HYPH
cord-262786-otxpc46a	102	13	amyloid	amyloid	NN
cord-262786-otxpc46a	102	14	,	,	,
cord-262786-otxpc46a	102	15	and	and	CC
cord-262786-otxpc46a	102	16	ApoE	ApoE	NNPS
cord-262786-otxpc46a	102	17	e4-positive	e4-positive	NNP
cord-262786-otxpc46a	102	18	mice	mouse	NNS
cord-262786-otxpc46a	102	19	exhibit	exhibit	NN
cord-262786-otxpc46a	102	20	increased	increase	VBN
cord-262786-otxpc46a	102	21	accumulation	accumulation	NN
cord-262786-otxpc46a	102	22	of	of	IN
cord-262786-otxpc46a	102	23	tau	tau	NNP
cord-262786-otxpc46a	102	24	aggregates	aggregate	NNS
cord-262786-otxpc46a	102	25	[	[	-LRB-
cord-262786-otxpc46a	102	26	50	50	CD
cord-262786-otxpc46a	102	27	]	]	-RRB-
cord-262786-otxpc46a	102	28	.	.	.
cord-262786-otxpc46a	103	1	In	in	IN
cord-262786-otxpc46a	103	2	line	line	NN
cord-262786-otxpc46a	103	3	with	with	IN
cord-262786-otxpc46a	103	4	these	these	DT
cord-262786-otxpc46a	103	5	,	,	,
cord-262786-otxpc46a	103	6	homozygote	homozygote	NNP
cord-262786-otxpc46a	103	7	ApoE	ApoE	NNP
cord-262786-otxpc46a	103	8	e4e4	e4e4	VBP
cord-262786-otxpc46a	103	9	not	not	RB
cord-262786-otxpc46a	103	10	only	only	RB
cord-262786-otxpc46a	103	11	acts	act	VBZ
cord-262786-otxpc46a	103	12	as	as	IN
cord-262786-otxpc46a	103	13	a	a	DT
cord-262786-otxpc46a	103	14	risk	risk	NN
cord-262786-otxpc46a	103	15	factor	factor	NN
cord-262786-otxpc46a	103	16	for	for	IN
cord-262786-otxpc46a	103	17	severe	severe	JJ
cord-262786-otxpc46a	103	18	SARS	SARS	NNP
cord-262786-otxpc46a	103	19	-	-	HYPH
cord-262786-otxpc46a	103	20	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	103	21	infection	infection	NN
cord-262786-otxpc46a	103	22	but	but	CC
cord-262786-otxpc46a	103	23	also	also	RB
cord-262786-otxpc46a	103	24	confers	confer	VBZ
cord-262786-otxpc46a	103	25	a	a	DT
cord-262786-otxpc46a	103	26	14-fold	14-fold	CD
cord-262786-otxpc46a	103	27	increase	increase	NN
cord-262786-otxpc46a	103	28	in	in	IN
cord-262786-otxpc46a	103	29	susceptibility	susceptibility	NN
cord-262786-otxpc46a	103	30	to	to	IN
cord-262786-otxpc46a	103	31	AD	ad	NN
cord-262786-otxpc46a	103	32	[	[	-LRB-
cord-262786-otxpc46a	103	33	49	49	CD
cord-262786-otxpc46a	103	34	]	]	-RRB-
cord-262786-otxpc46a	103	35	.	.	.
cord-262786-otxpc46a	104	1	A	a	DT
cord-262786-otxpc46a	104	2	growing	grow	VBG
cord-262786-otxpc46a	104	3	body	body	NN
cord-262786-otxpc46a	104	4	of	of	IN
cord-262786-otxpc46a	104	5	evidence	evidence	NN
cord-262786-otxpc46a	104	6	implicates	implicate	VBZ
cord-262786-otxpc46a	104	7	that	that	IN
cord-262786-otxpc46a	104	8	neuroinflammation	neuroinflammation	NN
cord-262786-otxpc46a	104	9	may	may	MD
cord-262786-otxpc46a	104	10	be	be	VB
cord-262786-otxpc46a	104	11	an	an	DT
cord-262786-otxpc46a	104	12	origin	origin	NN
cord-262786-otxpc46a	104	13	of	of	IN
cord-262786-otxpc46a	104	14	AD	ad	NN
cord-262786-otxpc46a	104	15	.	.	.
cord-262786-otxpc46a	105	1	Persistent	persistent	JJ
cord-262786-otxpc46a	105	2	systemic	systemic	JJ
cord-262786-otxpc46a	105	3	inflammation	inflammation	NN
cord-262786-otxpc46a	105	4	can	can	MD
cord-262786-otxpc46a	105	5	activate	activate	VB
cord-262786-otxpc46a	105	6	glial	glial	JJ
cord-262786-otxpc46a	105	7	cells	cell	NNS
cord-262786-otxpc46a	105	8	like	like	IN
cord-262786-otxpc46a	105	9	microglia	microglia	NNS
cord-262786-otxpc46a	105	10	and	and	CC
cord-262786-otxpc46a	105	11	astrocytes	astrocyte	NNS
cord-262786-otxpc46a	105	12	.	.	.
cord-262786-otxpc46a	106	1	Activated	activate	VBN
cord-262786-otxpc46a	106	2	microglia	microglia	NNS
cord-262786-otxpc46a	106	3	secrete	secrete	VBP
cord-262786-otxpc46a	106	4	pro	pro	JJ
cord-262786-otxpc46a	106	5	-	-	JJ
cord-262786-otxpc46a	106	6	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	106	7	cytokines	cytokine	NNS
cord-262786-otxpc46a	106	8	(	(	-LRB-
cord-262786-otxpc46a	106	9	e.g.	e.g.	RB
cord-262786-otxpc46a	106	10	,	,	,
cord-262786-otxpc46a	106	11	IL-1β	IL-1β	NNP
cord-262786-otxpc46a	106	12	,	,	,
cord-262786-otxpc46a	106	13	IL-6	IL-6	NNP
cord-262786-otxpc46a	106	14	,	,	,
cord-262786-otxpc46a	106	15	IL-12	IL-12	NNP
cord-262786-otxpc46a	106	16	,	,	,
cord-262786-otxpc46a	106	17	TNF	TNF	NNP
cord-262786-otxpc46a	106	18	-	-	HYPH
cord-262786-otxpc46a	106	19	α	α	NNP
cord-262786-otxpc46a	106	20	)	)	-RRB-
cord-262786-otxpc46a	106	21	[	[	-LRB-
cord-262786-otxpc46a	106	22	37	37	CD
cord-262786-otxpc46a	106	23	,	,	,
cord-262786-otxpc46a	106	24	51	51	CD
cord-262786-otxpc46a	106	25	]	]	-RRB-
cord-262786-otxpc46a	106	26	.	.	.
cord-262786-otxpc46a	107	1	We	-PRON-	PRP
cord-262786-otxpc46a	107	2	hypothesize	hypothesize	VBP
cord-262786-otxpc46a	107	3	that	that	IN
cord-262786-otxpc46a	107	4	not	not	RB
cord-262786-otxpc46a	107	5	only	only	RB
cord-262786-otxpc46a	107	6	the	the	DT
cord-262786-otxpc46a	107	7	persistent	persistent	JJ
cord-262786-otxpc46a	107	8	systemic	systemic	JJ
cord-262786-otxpc46a	107	9	inflammation	inflammation	NN
cord-262786-otxpc46a	107	10	caused	cause	VBN
cord-262786-otxpc46a	107	11	by	by	IN
cord-262786-otxpc46a	107	12	SARS	SARS	NNP
cord-262786-otxpc46a	107	13	-	-	HYPH
cord-262786-otxpc46a	107	14	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	107	15	may	may	MD
cord-262786-otxpc46a	107	16	act	act	VB
cord-262786-otxpc46a	107	17	as	as	IN
cord-262786-otxpc46a	107	18	a	a	DT
cord-262786-otxpc46a	107	19	trigger	trigger	NN
cord-262786-otxpc46a	107	20	for	for	IN
cord-262786-otxpc46a	107	21	microglial	microglial	JJ
cord-262786-otxpc46a	107	22	activation	activation	NN
cord-262786-otxpc46a	107	23	but	but	CC
cord-262786-otxpc46a	107	24	also	also	RB
cord-262786-otxpc46a	107	25	large	large	JJ
cord-262786-otxpc46a	107	26	amounts	amount	NNS
cord-262786-otxpc46a	107	27	of	of	IN
cord-262786-otxpc46a	107	28	pro	pro	JJ
cord-262786-otxpc46a	107	29	-	-	JJ
cord-262786-otxpc46a	107	30	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	107	31	cytokines	cytokine	NNS
cord-262786-otxpc46a	107	32	secreted	secrete	VBN
cord-262786-otxpc46a	107	33	in	in	IN
cord-262786-otxpc46a	107	34	response	response	NN
cord-262786-otxpc46a	107	35	to	to	IN
cord-262786-otxpc46a	107	36	this	this	DT
cord-262786-otxpc46a	107	37	viral	viral	JJ
cord-262786-otxpc46a	107	38	infection	infection	NN
cord-262786-otxpc46a	107	39	may	may	MD
cord-262786-otxpc46a	107	40	aggravate	aggravate	VB
cord-262786-otxpc46a	107	41	neurodegeneration	neurodegeneration	NN
cord-262786-otxpc46a	107	42	leading	lead	VBG
cord-262786-otxpc46a	107	43	to	to	IN
cord-262786-otxpc46a	107	44	AD	ad	NN
cord-262786-otxpc46a	107	45	.	.	.
cord-262786-otxpc46a	108	1	Elevated	elevated	JJ
cord-262786-otxpc46a	108	2	levels	level	NNS
cord-262786-otxpc46a	108	3	of	of	IN
cord-262786-otxpc46a	108	4	TNF	TNF	NNP
cord-262786-otxpc46a	108	5	-	-	HYPH
cord-262786-otxpc46a	108	6	α	α	NNP
cord-262786-otxpc46a	108	7	associate	associate	NN
cord-262786-otxpc46a	108	8	with	with	IN
cord-262786-otxpc46a	108	9	a	a	DT
cord-262786-otxpc46a	108	10	4-fold	4-fold	CD
cord-262786-otxpc46a	108	11	increase	increase	NN
cord-262786-otxpc46a	108	12	in	in	IN
cord-262786-otxpc46a	108	13	cognitive	cognitive	JJ
cord-262786-otxpc46a	108	14	dysfunction	dysfunction	NN
cord-262786-otxpc46a	108	15	[	[	-LRB-
cord-262786-otxpc46a	108	16	37	37	CD
cord-262786-otxpc46a	108	17	]	]	-RRB-
cord-262786-otxpc46a	108	18	.	.	.
cord-262786-otxpc46a	109	1	Increased	increase	VBN
cord-262786-otxpc46a	109	2	IL-1β	IL-1β	NNP
cord-262786-otxpc46a	109	3	and	and	CC
cord-262786-otxpc46a	109	4	IL-6	IL-6	NNP
cord-262786-otxpc46a	109	5	mitigates	mitigate	VBZ
cord-262786-otxpc46a	109	6	microglial	microglial	JJ
cord-262786-otxpc46a	109	7	phagocytosis	phagocytosis	NN
cord-262786-otxpc46a	109	8	of	of	IN
cord-262786-otxpc46a	109	9	β	β	NN
cord-262786-otxpc46a	109	10	-	-	HYPH
cord-262786-otxpc46a	109	11	amyloid	amyloid	NN
cord-262786-otxpc46a	109	12	plaques	plaque	NNS
cord-262786-otxpc46a	109	13	and	and	CC
cord-262786-otxpc46a	109	14	thus	thus	RB
cord-262786-otxpc46a	109	15	impairs	impair	VBZ
cord-262786-otxpc46a	109	16	synaptic	synaptic	JJ
cord-262786-otxpc46a	109	17	plasticity	plasticity	NN
cord-262786-otxpc46a	109	18	and	and	CC
cord-262786-otxpc46a	109	19	memory	memory	NN
cord-262786-otxpc46a	109	20	[	[	-LRB-
cord-262786-otxpc46a	109	21	19	19	CD
cord-262786-otxpc46a	109	22	,	,	,
cord-262786-otxpc46a	109	23	25	25	CD
cord-262786-otxpc46a	109	24	]	]	-RRB-
cord-262786-otxpc46a	109	25	.	.	.
cord-262786-otxpc46a	110	1	IFN	IFN	NNP
cord-262786-otxpc46a	110	2	induces	induce	VBZ
cord-262786-otxpc46a	110	3	synaptic	synaptic	JJ
cord-262786-otxpc46a	110	4	degeneration	degeneration	NN
cord-262786-otxpc46a	110	5	as	as	IN
cord-262786-otxpc46a	110	6	a	a	DT
cord-262786-otxpc46a	110	7	mediator	mediator	NN
cord-262786-otxpc46a	110	8	of	of	IN
cord-262786-otxpc46a	110	9	post	post	JJ
cord-262786-otxpc46a	110	10	-	-	JJ
cord-262786-otxpc46a	110	11	viral	viral	JJ
cord-262786-otxpc46a	110	12	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	110	13	response	response	NN
cord-262786-otxpc46a	110	14	.	.	.
cord-262786-otxpc46a	111	1	It	-PRON-	PRP
cord-262786-otxpc46a	111	2	is	be	VBZ
cord-262786-otxpc46a	111	3	worth	worth	JJ
cord-262786-otxpc46a	111	4	knowing	know	VBG
cord-262786-otxpc46a	111	5	that	that	IN
cord-262786-otxpc46a	111	6	βamyloids	βamyloids	NNP
cord-262786-otxpc46a	111	7	can	can	MD
cord-262786-otxpc46a	111	8	encircle	encircle	VB
cord-262786-otxpc46a	111	9	viral	viral	JJ
cord-262786-otxpc46a	111	10	particles	particle	NNS
cord-262786-otxpc46a	111	11	and	and	CC
cord-262786-otxpc46a	111	12	enhance	enhance	VB
cord-262786-otxpc46a	111	13	the	the	DT
cord-262786-otxpc46a	111	14	aforementioned	aforementioned	JJ
cord-262786-otxpc46a	111	15	IFN	IFN	NNP
cord-262786-otxpc46a	111	16	-	-	HYPH
cord-262786-otxpc46a	111	17	mediated	mediate	VBN
cord-262786-otxpc46a	111	18	response	response	NN
cord-262786-otxpc46a	111	19	[	[	-LRB-
cord-262786-otxpc46a	111	20	52	52	CD
cord-262786-otxpc46a	111	21	]	]	-RRB-
cord-262786-otxpc46a	111	22	.	.	.
cord-262786-otxpc46a	112	1	On	on	IN
cord-262786-otxpc46a	112	2	the	the	DT
cord-262786-otxpc46a	112	3	other	other	JJ
cord-262786-otxpc46a	112	4	hand	hand	NN
cord-262786-otxpc46a	112	5	,	,	,
cord-262786-otxpc46a	112	6	NOD-	NOD-	NNP
cord-262786-otxpc46a	112	7	,	,	,
cord-262786-otxpc46a	112	8	LRR-	LRR-	NNP
cord-262786-otxpc46a	112	9	,	,	,
cord-262786-otxpc46a	112	10	and	and	CC
cord-262786-otxpc46a	112	11	pyrin	pyrin	NNP
cord-262786-otxpc46a	112	12	domain	domain	NN
cord-262786-otxpc46a	112	13	-	-	HYPH
cord-262786-otxpc46a	112	14	containing	contain	VBG
cord-262786-otxpc46a	112	15	protein	protein	NN
cord-262786-otxpc46a	112	16	3	3	CD
cord-262786-otxpc46a	113	1	(	(	-LRB-
cord-262786-otxpc46a	113	2	NLRP3	NLRP3	NNP
cord-262786-otxpc46a	113	3	)	)	-RRB-
cord-262786-otxpc46a	113	4	inflammasomes	inflammasome	NNS
cord-262786-otxpc46a	113	5	play	play	VBP
cord-262786-otxpc46a	113	6	a	a	DT
cord-262786-otxpc46a	113	7	role	role	NN
cord-262786-otxpc46a	113	8	in	in	IN
cord-262786-otxpc46a	113	9	microgliamediated	microgliamediated	NNP
cord-262786-otxpc46a	113	10	IL-1β	IL-1β	NNP
cord-262786-otxpc46a	113	11	release	release	NN
cord-262786-otxpc46a	113	12	in	in	IN
cord-262786-otxpc46a	113	13	AD	ad	NN
cord-262786-otxpc46a	113	14	.	.	.
cord-262786-otxpc46a	114	1	SARS	SARS	NNP
cord-262786-otxpc46a	114	2	-	-	HYPH
cord-262786-otxpc46a	114	3	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	114	4	open	open	JJ
cord-262786-otxpc46a	114	5	reading	reading	NN
cord-262786-otxpc46a	114	6	frame	frame	NN
cord-262786-otxpc46a	114	7	3a	3a	CD
cord-262786-otxpc46a	114	8	(	(	-LRB-
cord-262786-otxpc46a	115	1	ORF3a	ORF3a	NNP
cord-262786-otxpc46a	115	2	)	)	-RRB-
cord-262786-otxpc46a	115	3	protein	protein	NN
cord-262786-otxpc46a	115	4	stimulates	stimulate	VBZ
cord-262786-otxpc46a	115	5	NLRP3	NLRP3	NNP
cord-262786-otxpc46a	115	6	inflammasomes	inflammasome	NNS
cord-262786-otxpc46a	115	7	,	,	,
cord-262786-otxpc46a	115	8	activation	activation	NN
cord-262786-otxpc46a	115	9	of	of	IN
cord-262786-otxpc46a	115	10	which	which	WDT
cord-262786-otxpc46a	115	11	accelerates	accelerate	VBZ
cord-262786-otxpc46a	115	12	the	the	DT
cord-262786-otxpc46a	115	13	neurodegeneration	neurodegeneration	NN
cord-262786-otxpc46a	115	14	process	process	NN
cord-262786-otxpc46a	115	15	in	in	IN
cord-262786-otxpc46a	115	16	AD	ad	NN
cord-262786-otxpc46a	115	17	[	[	-LRB-
cord-262786-otxpc46a	115	18	12	12	CD
cord-262786-otxpc46a	115	19	]	]	-RRB-
cord-262786-otxpc46a	115	20	.	.	.
cord-262786-otxpc46a	116	1	PD	PD	NNP
cord-262786-otxpc46a	116	2	,	,	,
cord-262786-otxpc46a	116	3	the	the	DT
cord-262786-otxpc46a	116	4	second	second	JJ
cord-262786-otxpc46a	116	5	most	most	RBS
cord-262786-otxpc46a	116	6	common	common	JJ
cord-262786-otxpc46a	116	7	neurodegenerative	neurodegenerative	JJ
cord-262786-otxpc46a	116	8	disorder	disorder	NN
cord-262786-otxpc46a	116	9	,	,	,
cord-262786-otxpc46a	116	10	is	be	VBZ
cord-262786-otxpc46a	116	11	characterized	characterize	VBN
cord-262786-otxpc46a	116	12	by	by	IN
cord-262786-otxpc46a	116	13	the	the	DT
cord-262786-otxpc46a	116	14	degeneration	degeneration	NN
cord-262786-otxpc46a	116	15	of	of	IN
cord-262786-otxpc46a	116	16	dopaminergic	dopaminergic	JJ
cord-262786-otxpc46a	116	17	neurons	neuron	NNS
cord-262786-otxpc46a	116	18	of	of	IN
cord-262786-otxpc46a	116	19	substantia	substantia	NNP
cord-262786-otxpc46a	116	20	nigra	nigra	NNP
cord-262786-otxpc46a	116	21	pars	pars	NNP
cord-262786-otxpc46a	116	22	compacta	compacta	NN
cord-262786-otxpc46a	116	23	,	,	,
cord-262786-otxpc46a	116	24	along	along	IN
cord-262786-otxpc46a	116	25	with	with	IN
cord-262786-otxpc46a	116	26	microscopic	microscopic	JJ
cord-262786-otxpc46a	116	27	findings	finding	NNS
cord-262786-otxpc46a	116	28	of	of	IN
cord-262786-otxpc46a	116	29	intracellular	intracellular	JJ
cord-262786-otxpc46a	116	30	α	α	NNP
cord-262786-otxpc46a	116	31	-	-	HYPH
cord-262786-otxpc46a	116	32	synuclein	synuclein	NNP
cord-262786-otxpc46a	116	33	aggregates	aggregate	NNS
cord-262786-otxpc46a	116	34	[	[	-LRB-
cord-262786-otxpc46a	116	35	53	53	CD
cord-262786-otxpc46a	116	36	]	]	-RRB-
cord-262786-otxpc46a	117	1	[	[	-LRB-
cord-262786-otxpc46a	117	2	54	54	CD
cord-262786-otxpc46a	117	3	]	]	-RRB-
cord-262786-otxpc46a	118	1	[	[	-LRB-
cord-262786-otxpc46a	118	2	55	55	CD
cord-262786-otxpc46a	118	3	]	]	-RRB-
cord-262786-otxpc46a	118	4	[	[	-LRB-
cord-262786-otxpc46a	118	5	56	56	CD
cord-262786-otxpc46a	118	6	]	]	-RRB-
cord-262786-otxpc46a	118	7	.	.	.
cord-262786-otxpc46a	119	1	Autoantibodies	Autoantibodies	NNP
cord-262786-otxpc46a	119	2	against	against	IN
cord-262786-otxpc46a	119	3	α	α	NNP
cord-262786-otxpc46a	119	4	-	-	HYPH
cord-262786-otxpc46a	119	5	synuclein	synuclein	NNP
cord-262786-otxpc46a	119	6	,	,	,
cord-262786-otxpc46a	119	7	gangliosides	ganglioside	NNS
cord-262786-otxpc46a	119	8	,	,	,
cord-262786-otxpc46a	119	9	pigment	pigment	NN
cord-262786-otxpc46a	119	10	neuromelanin	neuromelanin	NNP
cord-262786-otxpc46a	120	1	Ma1	Ma1	NNP
cord-262786-otxpc46a	120	2	/	/	SYM
cord-262786-otxpc46a	120	3	Ma2	ma2	NN
cord-262786-otxpc46a	120	4	,	,	,
cord-262786-otxpc46a	120	5	leucine	leucine	NN
cord-262786-otxpc46a	120	6	-	-	HYPH
cord-262786-otxpc46a	120	7	rich	rich	JJ
cord-262786-otxpc46a	120	8	glioma	glioma	NN
cord-262786-otxpc46a	120	9	inactivated	inactivate	VBD
cord-262786-otxpc46a	120	10	1	1	CD
cord-262786-otxpc46a	120	11	(	(	-LRB-
cord-262786-otxpc46a	120	12	LGI1	LGI1	NNP
cord-262786-otxpc46a	120	13	)	)	-RRB-
cord-262786-otxpc46a	120	14	,	,	,
cord-262786-otxpc46a	120	15	and	and	CC
cord-262786-otxpc46a	120	16	glutamic	glutamic	NN
cord-262786-otxpc46a	120	17	acid	acid	NN
cord-262786-otxpc46a	120	18	decarboxylase	decarboxylase	NN
cord-262786-otxpc46a	120	19	(	(	-LRB-
cord-262786-otxpc46a	120	20	GAD65	GAD65	NNP
cord-262786-otxpc46a	120	21	)	)	-RRB-
cord-262786-otxpc46a	120	22	are	be	VBP
cord-262786-otxpc46a	120	23	found	find	VBN
cord-262786-otxpc46a	120	24	in	in	IN
cord-262786-otxpc46a	120	25	the	the	DT
cord-262786-otxpc46a	120	26	serum	serum	NN
cord-262786-otxpc46a	120	27	of	of	IN
cord-262786-otxpc46a	120	28	PD	PD	NNP
cord-262786-otxpc46a	120	29	patients	patient	NNS
cord-262786-otxpc46a	120	30	,	,	,
cord-262786-otxpc46a	120	31	which	which	WDT
cord-262786-otxpc46a	120	32	implicate	implicate	VBP
cord-262786-otxpc46a	120	33	a	a	DT
cord-262786-otxpc46a	120	34	role	role	NN
cord-262786-otxpc46a	120	35	for	for	IN
cord-262786-otxpc46a	120	36	autoimmunity	autoimmunity	NN
cord-262786-otxpc46a	120	37	in	in	IN
cord-262786-otxpc46a	120	38	the	the	DT
cord-262786-otxpc46a	120	39	pathogenesis	pathogenesis	NN
cord-262786-otxpc46a	120	40	of	of	IN
cord-262786-otxpc46a	120	41	PD	PD	NNP
cord-262786-otxpc46a	120	42	[	[	-LRB-
cord-262786-otxpc46a	120	43	53	53	CD
cord-262786-otxpc46a	120	44	]	]	-RRB-
cord-262786-otxpc46a	120	45	.	.	.
cord-262786-otxpc46a	121	1	Knowing	know	VBG
cord-262786-otxpc46a	121	2	that	that	IN
cord-262786-otxpc46a	121	3	SARS	SARS	NNP
cord-262786-otxpc46a	121	4	-	-	HYPH
cord-262786-otxpc46a	121	5	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	121	6	may	may	MD
cord-262786-otxpc46a	121	7	remain	remain	VB
cord-262786-otxpc46a	121	8	latent	latent	JJ
cord-262786-otxpc46a	121	9	in	in	IN
cord-262786-otxpc46a	121	10	neurons	neuron	NNS
cord-262786-otxpc46a	121	11	,	,	,
cord-262786-otxpc46a	121	12	we	-PRON-	PRP
cord-262786-otxpc46a	121	13	hypothesize	hypothesize	VBP
cord-262786-otxpc46a	121	14	that	that	IN
cord-262786-otxpc46a	121	15	autoimmunity	autoimmunity	NN
cord-262786-otxpc46a	121	16	in	in	IN
cord-262786-otxpc46a	121	17	SARS	SARS	NNP
cord-262786-otxpc46a	121	18	-	-	HYPH
cord-262786-otxpc46a	121	19	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	121	20	infection	infection	NN
cord-262786-otxpc46a	121	21	due	due	JJ
cord-262786-otxpc46a	121	22	to	to	IN
cord-262786-otxpc46a	121	23	crossreactivity	crossreactivity	NN
cord-262786-otxpc46a	121	24	mediated	mediate	VBN
cord-262786-otxpc46a	121	25	by	by	IN
cord-262786-otxpc46a	121	26	antiviral	antiviral	JJ
cord-262786-otxpc46a	121	27	antibodies	antibody	NNS
cord-262786-otxpc46a	121	28	may	may	MD
cord-262786-otxpc46a	121	29	lead	lead	VB
cord-262786-otxpc46a	121	30	to	to	IN
cord-262786-otxpc46a	121	31	delayed	delay	VBN
cord-262786-otxpc46a	121	32	progression	progression	NN
cord-262786-otxpc46a	121	33	of	of	IN
cord-262786-otxpc46a	121	34	PD	PD	NNP
cord-262786-otxpc46a	121	35	[	[	-LRB-
cord-262786-otxpc46a	121	36	28	28	CD
cord-262786-otxpc46a	121	37	]	]	-RRB-
cord-262786-otxpc46a	121	38	.	.	.
cord-262786-otxpc46a	122	1	This	this	DT
cord-262786-otxpc46a	122	2	hypothesis	hypothesis	NN
cord-262786-otxpc46a	122	3	is	be	VBZ
cord-262786-otxpc46a	122	4	supported	support	VBN
cord-262786-otxpc46a	122	5	by	by	IN
cord-262786-otxpc46a	122	6	the	the	DT
cord-262786-otxpc46a	122	7	fact	fact	NN
cord-262786-otxpc46a	122	8	that	that	IN
cord-262786-otxpc46a	122	9	anti	anti	JJ
cord-262786-otxpc46a	122	10	-	-	JJ
cord-262786-otxpc46a	122	11	CoV	cov	JJ
cord-262786-otxpc46a	122	12	antibodies	antibody	NNS
cord-262786-otxpc46a	122	13	are	be	VBP
cord-262786-otxpc46a	122	14	found	find	VBN
cord-262786-otxpc46a	122	15	in	in	IN
cord-262786-otxpc46a	122	16	the	the	DT
cord-262786-otxpc46a	122	17	CSF	CSF	NNP
cord-262786-otxpc46a	122	18	of	of	IN
cord-262786-otxpc46a	122	19	PD	PD	NNP
cord-262786-otxpc46a	122	20	patients	patient	NNS
cord-262786-otxpc46a	122	21	[	[	-LRB-
cord-262786-otxpc46a	122	22	28	28	CD
cord-262786-otxpc46a	122	23	]	]	-RRB-
cord-262786-otxpc46a	122	24	.	.	.
cord-262786-otxpc46a	123	1	We	-PRON-	PRP
cord-262786-otxpc46a	123	2	also	also	RB
cord-262786-otxpc46a	123	3	postulate	postulate	VBP
cord-262786-otxpc46a	123	4	that	that	IN
cord-262786-otxpc46a	123	5	aberrant	aberrant	JJ
cord-262786-otxpc46a	123	6	cytokine	cytokine	NN
cord-262786-otxpc46a	123	7	release	release	NN
cord-262786-otxpc46a	123	8	into	into	IN
cord-262786-otxpc46a	123	9	the	the	DT
cord-262786-otxpc46a	123	10	CSF	CSF	NNP
cord-262786-otxpc46a	123	11	of	of	IN
cord-262786-otxpc46a	123	12	SARS	SARS	NNP
cord-262786-otxpc46a	123	13	-	-	HYPH
cord-262786-otxpc46a	123	14	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	123	15	patients	patient	NNS
cord-262786-otxpc46a	123	16	may	may	MD
cord-262786-otxpc46a	123	17	increase	increase	VB
cord-262786-otxpc46a	123	18	the	the	DT
cord-262786-otxpc46a	123	19	risk	risk	NN
cord-262786-otxpc46a	123	20	of	of	IN
cord-262786-otxpc46a	123	21	progression	progression	NN
cord-262786-otxpc46a	123	22	into	into	IN
cord-262786-otxpc46a	123	23	PD	PD	NNP
cord-262786-otxpc46a	123	24	by	by	IN
cord-262786-otxpc46a	123	25	aggravating	aggravate	VBG
cord-262786-otxpc46a	123	26	the	the	DT
cord-262786-otxpc46a	123	27	neurodegeneration	neurodegeneration	NN
cord-262786-otxpc46a	123	28	process	process	NN
cord-262786-otxpc46a	123	29	,	,	,
cord-262786-otxpc46a	123	30	considering	consider	VBG
cord-262786-otxpc46a	123	31	the	the	DT
cord-262786-otxpc46a	123	32	fact	fact	NN
cord-262786-otxpc46a	123	33	that	that	IN
cord-262786-otxpc46a	123	34	PD	PD	NNP
cord-262786-otxpc46a	123	35	patients	patient	NNS
cord-262786-otxpc46a	123	36	exhibit	exhibit	VBP
cord-262786-otxpc46a	123	37	elevated	elevated	JJ
cord-262786-otxpc46a	123	38	levels	level	NNS
cord-262786-otxpc46a	123	39	of	of	IN
cord-262786-otxpc46a	123	40	pro	pro	JJ
cord-262786-otxpc46a	123	41	-	-	JJ
cord-262786-otxpc46a	123	42	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	123	43	cytokines	cytokine	NNS
cord-262786-otxpc46a	123	44	(	(	-LRB-
cord-262786-otxpc46a	123	45	including	include	VBG
cord-262786-otxpc46a	123	46	IL-1β	IL-1β	NNP
cord-262786-otxpc46a	123	47	,	,	,
cord-262786-otxpc46a	123	48	IL-6	IL-6	NNP
cord-262786-otxpc46a	123	49	,	,	,
cord-262786-otxpc46a	123	50	TNF	TNF	NNP
cord-262786-otxpc46a	123	51	-	-	HYPH
cord-262786-otxpc46a	123	52	α	α	NNP
cord-262786-otxpc46a	123	53	,	,	,
cord-262786-otxpc46a	123	54	and	and	CC
cord-262786-otxpc46a	123	55	IFN	IFN	NNP
cord-262786-otxpc46a	123	56	-	-	HYPH
cord-262786-otxpc46a	123	57	γ	γ	NNP
cord-262786-otxpc46a	123	58	)	)	-RRB-
cord-262786-otxpc46a	123	59	in	in	IN
cord-262786-otxpc46a	123	60	CSF	CSF	NNP
cord-262786-otxpc46a	123	61	.	.	.
cord-262786-otxpc46a	124	1	Cytokine	cytokine	NN
cord-262786-otxpc46a	124	2	storm	storm	NN
cord-262786-otxpc46a	124	3	activates	activate	VBZ
cord-262786-otxpc46a	124	4	microglia	microglia	NNS
cord-262786-otxpc46a	124	5	,	,	,
cord-262786-otxpc46a	124	6	which	which	WDT
cord-262786-otxpc46a	124	7	are	be	VBP
cord-262786-otxpc46a	124	8	implicated	implicate	VBN
cord-262786-otxpc46a	124	9	in	in	IN
cord-262786-otxpc46a	124	10	the	the	DT
cord-262786-otxpc46a	124	11	pathophysiology	pathophysiology	NN
cord-262786-otxpc46a	124	12	of	of	IN
cord-262786-otxpc46a	124	13	PD	PD	NNP
cord-262786-otxpc46a	124	14	[	[	-LRB-
cord-262786-otxpc46a	124	15	57	57	CD
cord-262786-otxpc46a	124	16	]	]	-RRB-
cord-262786-otxpc46a	124	17	.	.	.
cord-262786-otxpc46a	125	1	Moreover	moreover	RB
cord-262786-otxpc46a	125	2	,	,	,
cord-262786-otxpc46a	125	3	the	the	DT
cord-262786-otxpc46a	125	4	extreme	extreme	JJ
cord-262786-otxpc46a	125	5	release	release	NN
cord-262786-otxpc46a	125	6	of	of	IN
cord-262786-otxpc46a	125	7	cytokines	cytokine	NNS
cord-262786-otxpc46a	125	8	into	into	IN
cord-262786-otxpc46a	125	9	the	the	DT
cord-262786-otxpc46a	125	10	CSF	CSF	NNP
cord-262786-otxpc46a	125	11	mediated	mediate	VBN
cord-262786-otxpc46a	125	12	by	by	IN
cord-262786-otxpc46a	125	13	SARS	SARS	NNP
cord-262786-otxpc46a	125	14	-	-	HYPH
cord-262786-otxpc46a	125	15	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	125	16	dysregulates	dysregulate	VBZ
cord-262786-otxpc46a	125	17	the	the	DT
cord-262786-otxpc46a	125	18	balance	balance	NN
cord-262786-otxpc46a	125	19	between	between	IN
cord-262786-otxpc46a	125	20	production	production	NN
cord-262786-otxpc46a	125	21	,	,	,
cord-262786-otxpc46a	125	22	release	release	NN
cord-262786-otxpc46a	125	23	,	,	,
cord-262786-otxpc46a	125	24	and	and	CC
cord-262786-otxpc46a	125	25	reuptake	reuptake	NN
cord-262786-otxpc46a	125	26	of	of	IN
cord-262786-otxpc46a	125	27	neurotransmitters	neurotransmitter	NNS
cord-262786-otxpc46a	125	28	including	include	VBG
cord-262786-otxpc46a	125	29	dopamine	dopamine	NN
cord-262786-otxpc46a	125	30	,	,	,
cord-262786-otxpc46a	125	31	which	which	WDT
cord-262786-otxpc46a	125	32	possibly	possibly	RB
cord-262786-otxpc46a	125	33	contributes	contribute	VBZ
cord-262786-otxpc46a	125	34	to	to	IN
cord-262786-otxpc46a	125	35	the	the	DT
cord-262786-otxpc46a	125	36	development	development	NN
cord-262786-otxpc46a	125	37	of	of	IN
cord-262786-otxpc46a	125	38	PD	PD	NNP
cord-262786-otxpc46a	125	39	[	[	-LRB-
cord-262786-otxpc46a	125	40	25	25	CD
cord-262786-otxpc46a	125	41	]	]	-RRB-
cord-262786-otxpc46a	125	42	.	.	.
cord-262786-otxpc46a	126	1	Moreover	moreover	RB
cord-262786-otxpc46a	126	2	,	,	,
cord-262786-otxpc46a	126	3	the	the	DT
cord-262786-otxpc46a	126	4	common	common	JJ
cord-262786-otxpc46a	126	5	finding	finding	NN
cord-262786-otxpc46a	126	6	of	of	IN
cord-262786-otxpc46a	126	7	anosmia	anosmia	NN
cord-262786-otxpc46a	126	8	(	(	-LRB-
cord-262786-otxpc46a	126	9	total	total	JJ
cord-262786-otxpc46a	126	10	loss	loss	NN
cord-262786-otxpc46a	126	11	of	of	IN
cord-262786-otxpc46a	126	12	sense	sense	NN
cord-262786-otxpc46a	126	13	of	of	IN
cord-262786-otxpc46a	126	14	smell	smell	NN
cord-262786-otxpc46a	126	15	)	)	-RRB-
cord-262786-otxpc46a	126	16	in	in	IN
cord-262786-otxpc46a	126	17	PD	PD	NNP
cord-262786-otxpc46a	126	18	and	and	CC
cord-262786-otxpc46a	126	19	SARS	SARS	NNP
cord-262786-otxpc46a	126	20	-	-	HYPH
cord-262786-otxpc46a	126	21	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	126	22	reinforces	reinforce	VBZ
cord-262786-otxpc46a	126	23	their	-PRON-	PRP$
cord-262786-otxpc46a	126	24	association	association	NN
cord-262786-otxpc46a	126	25	.	.	.
cord-262786-otxpc46a	127	1	Anosmia	Anosmia	NNP
cord-262786-otxpc46a	127	2	is	be	VBZ
cord-262786-otxpc46a	127	3	a	a	DT
cord-262786-otxpc46a	127	4	common	common	JJ
cord-262786-otxpc46a	127	5	finding	finding	NN
cord-262786-otxpc46a	127	6	in	in	IN
cord-262786-otxpc46a	127	7	neurodegenerative	neurodegenerative	JJ
cord-262786-otxpc46a	127	8	diseases	disease	NNS
cord-262786-otxpc46a	127	9	[	[	-LRB-
cord-262786-otxpc46a	127	10	58	58	CD
cord-262786-otxpc46a	127	11	]	]	-RRB-
cord-262786-otxpc46a	127	12	,	,	,
cord-262786-otxpc46a	127	13	and	and	CC
cord-262786-otxpc46a	127	14	over	over	IN
cord-262786-otxpc46a	127	15	90	90	CD
cord-262786-otxpc46a	127	16	%	%	NN
cord-262786-otxpc46a	127	17	of	of	IN
cord-262786-otxpc46a	127	18	PD	PD	NNP
cord-262786-otxpc46a	127	19	patients	patient	NNS
cord-262786-otxpc46a	127	20	develop	develop	VBP
cord-262786-otxpc46a	127	21	anosmia	anosmia	NN
cord-262786-otxpc46a	127	22	or	or	CC
cord-262786-otxpc46a	127	23	hyposmia	hyposmia	NN
cord-262786-otxpc46a	127	24	(	(	-LRB-
cord-262786-otxpc46a	127	25	partial	partial	JJ
cord-262786-otxpc46a	127	26	loss	loss	NN
cord-262786-otxpc46a	127	27	of	of	IN
cord-262786-otxpc46a	127	28	sense	sense	NN
cord-262786-otxpc46a	127	29	of	of	IN
cord-262786-otxpc46a	127	30	smell	smell	NN
cord-262786-otxpc46a	127	31	)	)	-RRB-
cord-262786-otxpc46a	127	32	.	.	.
cord-262786-otxpc46a	128	1	Anosmia	Anosmia	NNP
cord-262786-otxpc46a	128	2	may	may	MD
cord-262786-otxpc46a	128	3	precede	precede	VB
cord-262786-otxpc46a	128	4	motor	motor	NN
cord-262786-otxpc46a	128	5	symptoms	symptom	NNS
cord-262786-otxpc46a	128	6	of	of	IN
cord-262786-otxpc46a	128	7	PD	PD	NNP
cord-262786-otxpc46a	128	8	and	and	CC
cord-262786-otxpc46a	128	9	thus	thus	RB
cord-262786-otxpc46a	128	10	can	can	MD
cord-262786-otxpc46a	128	11	be	be	VB
cord-262786-otxpc46a	128	12	used	use	VBN
cord-262786-otxpc46a	128	13	as	as	IN
cord-262786-otxpc46a	128	14	a	a	DT
cord-262786-otxpc46a	128	15	marker	marker	NN
cord-262786-otxpc46a	128	16	of	of	IN
cord-262786-otxpc46a	128	17	underlying	underlie	VBG
cord-262786-otxpc46a	128	18	neurodegeneration	neurodegeneration	NN
cord-262786-otxpc46a	128	19	[	[	-LRB-
cord-262786-otxpc46a	128	20	59	59	CD
cord-262786-otxpc46a	128	21	]	]	-RRB-
cord-262786-otxpc46a	128	22	.	.	.
cord-262786-otxpc46a	129	1	Although	although	IN
cord-262786-otxpc46a	129	2	MRI	MRI	NNP
cord-262786-otxpc46a	129	3	studies	study	NNS
cord-262786-otxpc46a	129	4	of	of	IN
cord-262786-otxpc46a	129	5	PD	PD	NNP
cord-262786-otxpc46a	129	6	patients	patient	NNS
cord-262786-otxpc46a	129	7	show	show	VBP
cord-262786-otxpc46a	129	8	that	that	IN
cord-262786-otxpc46a	129	9	volume	volume	NN
cord-262786-otxpc46a	129	10	and	and	CC
cord-262786-otxpc46a	129	11	sulcus	sulcus	NN
cord-262786-otxpc46a	129	12	depth	depth	NN
cord-262786-otxpc46a	129	13	of	of	IN
cord-262786-otxpc46a	129	14	olfactory	olfactory	JJ
cord-262786-otxpc46a	129	15	bulb	bulb	NN
cord-262786-otxpc46a	129	16	decrease	decrease	NN
cord-262786-otxpc46a	129	17	,	,	,
cord-262786-otxpc46a	129	18	biopsy	biopsy	NN
cord-262786-otxpc46a	129	19	samples	sample	NNS
cord-262786-otxpc46a	129	20	of	of	IN
cord-262786-otxpc46a	129	21	olfactory	olfactory	JJ
cord-262786-otxpc46a	129	22	epithelium	epithelium	NN
cord-262786-otxpc46a	129	23	are	be	VBP
cord-262786-otxpc46a	129	24	normal	normal	JJ
cord-262786-otxpc46a	129	25	in	in	IN
cord-262786-otxpc46a	129	26	these	these	DT
cord-262786-otxpc46a	129	27	patents	patent	NNS
cord-262786-otxpc46a	129	28	[	[	-LRB-
cord-262786-otxpc46a	129	29	60	60	CD
cord-262786-otxpc46a	129	30	]	]	-RRB-
cord-262786-otxpc46a	129	31	.	.	.
cord-262786-otxpc46a	130	1	These	these	DT
cord-262786-otxpc46a	130	2	findings	finding	NNS
cord-262786-otxpc46a	130	3	suggest	suggest	VBP
cord-262786-otxpc46a	130	4	that	that	IN
cord-262786-otxpc46a	130	5	the	the	DT
cord-262786-otxpc46a	130	6	observed	observed	JJ
cord-262786-otxpc46a	130	7	anosmia	anosmia	NN
cord-262786-otxpc46a	130	8	in	in	IN
cord-262786-otxpc46a	130	9	these	these	DT
cord-262786-otxpc46a	130	10	patients	patient	NNS
cord-262786-otxpc46a	130	11	is	be	VBZ
cord-262786-otxpc46a	130	12	due	due	JJ
cord-262786-otxpc46a	130	13	to	to	IN
cord-262786-otxpc46a	130	14	a	a	DT
cord-262786-otxpc46a	130	15	disturbance	disturbance	NN
cord-262786-otxpc46a	130	16	in	in	IN
cord-262786-otxpc46a	130	17	central	central	JJ
cord-262786-otxpc46a	130	18	and	and	CC
cord-262786-otxpc46a	130	19	not	not	RB
cord-262786-otxpc46a	130	20	peripheral	peripheral	JJ
cord-262786-otxpc46a	130	21	processing	processing	NN
cord-262786-otxpc46a	130	22	of	of	IN
cord-262786-otxpc46a	130	23	smell	smell	NN
cord-262786-otxpc46a	130	24	[	[	-LRB-
cord-262786-otxpc46a	130	25	60	60	CD
cord-262786-otxpc46a	130	26	]	]	-RRB-
cord-262786-otxpc46a	130	27	.	.	.
cord-262786-otxpc46a	131	1	Knowing	know	VBG
cord-262786-otxpc46a	131	2	that	that	IN
cord-262786-otxpc46a	131	3	autopsy	autopsy	JJ
cord-262786-otxpc46a	131	4	studies	study	NNS
cord-262786-otxpc46a	131	5	of	of	IN
cord-262786-otxpc46a	131	6	postmortem	postmortem	JJ
cord-262786-otxpc46a	131	7	PD	PD	NNP
cord-262786-otxpc46a	131	8	patients	patient	NNS
cord-262786-otxpc46a	131	9	suffering	suffer	VBG
cord-262786-otxpc46a	131	10	from	from	IN
cord-262786-otxpc46a	131	11	anosmia	anosmia	NN
cord-262786-otxpc46a	131	12	show	show	VBP
cord-262786-otxpc46a	131	13	abundant	abundant	JJ
cord-262786-otxpc46a	131	14	deposition	deposition	NN
cord-262786-otxpc46a	131	15	of	of	IN
cord-262786-otxpc46a	131	16	Lewy	Lewy	NNP
cord-262786-otxpc46a	131	17	bodies	body	NNS
cord-262786-otxpc46a	131	18	in	in	IN
cord-262786-otxpc46a	131	19	the	the	DT
cord-262786-otxpc46a	131	20	olfactory	olfactory	JJ
cord-262786-otxpc46a	131	21	bulb	bulb	NN
cord-262786-otxpc46a	131	22	,	,	,
cord-262786-otxpc46a	131	23	anosmia	anosmia	NN
cord-262786-otxpc46a	131	24	is	be	VBZ
cord-262786-otxpc46a	131	25	attributed	attribute	VBN
cord-262786-otxpc46a	131	26	to	to	IN
cord-262786-otxpc46a	131	27	the	the	DT
cord-262786-otxpc46a	131	28	distribution	distribution	NN
cord-262786-otxpc46a	131	29	of	of	IN
cord-262786-otxpc46a	131	30	Lewy	Lewy	NNP
cord-262786-otxpc46a	131	31	bodies	body	NNS
cord-262786-otxpc46a	131	32	from	from	IN
cord-262786-otxpc46a	131	33	the	the	DT
cord-262786-otxpc46a	131	34	medulla	medulla	NN
cord-262786-otxpc46a	131	35	in	in	IN
cord-262786-otxpc46a	131	36	early	early	JJ
cord-262786-otxpc46a	131	37	stages	stage	NNS
cord-262786-otxpc46a	131	38	of	of	IN
cord-262786-otxpc46a	131	39	PD	PD	NNP
cord-262786-otxpc46a	131	40	[	[	-LRB-
cord-262786-otxpc46a	131	41	61	61	CD
cord-262786-otxpc46a	131	42	]	]	-RRB-
cord-262786-otxpc46a	131	43	.	.	.
cord-262786-otxpc46a	132	1	However	however	RB
cord-262786-otxpc46a	132	2	,	,	,
cord-262786-otxpc46a	132	3	in	in	IN
cord-262786-otxpc46a	132	4	later	later	JJ
cord-262786-otxpc46a	132	5	stages	stage	NNS
cord-262786-otxpc46a	132	6	,	,	,
cord-262786-otxpc46a	132	7	cognitive	cognitive	JJ
cord-262786-otxpc46a	132	8	deficits	deficit	NNS
cord-262786-otxpc46a	132	9	and	and	CC
cord-262786-otxpc46a	132	10	cholinergic	cholinergic	JJ
cord-262786-otxpc46a	132	11	denervation	denervation	NN
cord-262786-otxpc46a	132	12	may	may	MD
cord-262786-otxpc46a	132	13	underlie	underlie	VB
cord-262786-otxpc46a	132	14	the	the	DT
cord-262786-otxpc46a	132	15	development	development	NN
cord-262786-otxpc46a	132	16	of	of	IN
cord-262786-otxpc46a	132	17	anosmia	anosmia	NN
cord-262786-otxpc46a	132	18	in	in	IN
cord-262786-otxpc46a	132	19	these	these	DT
cord-262786-otxpc46a	132	20	patients	patient	NNS
cord-262786-otxpc46a	132	21	[	[	-LRB-
cord-262786-otxpc46a	132	22	60	60	CD
cord-262786-otxpc46a	132	23	]	]	-RRB-
cord-262786-otxpc46a	132	24	.	.	.
cord-262786-otxpc46a	133	1	On	on	IN
cord-262786-otxpc46a	133	2	the	the	DT
cord-262786-otxpc46a	133	3	other	other	JJ
cord-262786-otxpc46a	133	4	hand	hand	NN
cord-262786-otxpc46a	133	5	,	,	,
cord-262786-otxpc46a	133	6	a	a	DT
cord-262786-otxpc46a	133	7	recent	recent	JJ
cord-262786-otxpc46a	133	8	review	review	NN
cord-262786-otxpc46a	133	9	reports	report	VBZ
cord-262786-otxpc46a	133	10	a	a	DT
cord-262786-otxpc46a	133	11	nearly	nearly	RB
cord-262786-otxpc46a	133	12	23	23	CD
cord-262786-otxpc46a	133	13	%	%	NN
cord-262786-otxpc46a	133	14	prevalence	prevalence	NN
cord-262786-otxpc46a	133	15	for	for	IN
cord-262786-otxpc46a	133	16	anosmia	anosmia	NN
cord-262786-otxpc46a	133	17	in	in	IN
cord-262786-otxpc46a	133	18	SARS	SARS	NNP
cord-262786-otxpc46a	133	19	-	-	HYPH
cord-262786-otxpc46a	133	20	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	133	21	patients	patient	NNS
cord-262786-otxpc46a	133	22	[	[	-LRB-
cord-262786-otxpc46a	133	23	62	62	CD
cord-262786-otxpc46a	133	24	]	]	-RRB-
cord-262786-otxpc46a	133	25	.	.	.
cord-262786-otxpc46a	134	1	Several	several	JJ
cord-262786-otxpc46a	134	2	explanations	explanation	NNS
cord-262786-otxpc46a	134	3	are	be	VBP
cord-262786-otxpc46a	134	4	suggested	suggest	VBN
cord-262786-otxpc46a	134	5	to	to	TO
cord-262786-otxpc46a	134	6	shed	shed	VB
cord-262786-otxpc46a	134	7	light	light	NN
cord-262786-otxpc46a	134	8	on	on	IN
cord-262786-otxpc46a	134	9	the	the	DT
cord-262786-otxpc46a	134	10	underlying	underlying	JJ
cord-262786-otxpc46a	134	11	cause	cause	NN
cord-262786-otxpc46a	134	12	of	of	IN
cord-262786-otxpc46a	134	13	anosmia	anosmia	NN
cord-262786-otxpc46a	134	14	in	in	IN
cord-262786-otxpc46a	134	15	SARS	SARS	NNP
cord-262786-otxpc46a	134	16	-	-	HYPH
cord-262786-otxpc46a	134	17	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	134	18	patients	patient	NNS
cord-262786-otxpc46a	134	19	.	.	.
cord-262786-otxpc46a	135	1	At	at	IN
cord-262786-otxpc46a	135	2	first	first	RB
cord-262786-otxpc46a	135	3	,	,	,
cord-262786-otxpc46a	135	4	it	-PRON-	PRP
cord-262786-otxpc46a	135	5	was	be	VBD
cord-262786-otxpc46a	135	6	hypothesized	hypothesize	VBN
cord-262786-otxpc46a	135	7	that	that	IN
cord-262786-otxpc46a	135	8	the	the	DT
cord-262786-otxpc46a	135	9	local	local	JJ
cord-262786-otxpc46a	135	10	inflammation	inflammation	NN
cord-262786-otxpc46a	135	11	and	and	CC
cord-262786-otxpc46a	135	12	the	the	DT
cord-262786-otxpc46a	135	13	resulting	result	VBG
cord-262786-otxpc46a	135	14	coryza	coryza	NNP
cord-262786-otxpc46a	135	15	and	and	CC
cord-262786-otxpc46a	135	16	sinusitis	sinusitis	NN
cord-262786-otxpc46a	135	17	account	account	NN
cord-262786-otxpc46a	135	18	for	for	IN
cord-262786-otxpc46a	135	19	anosmia	anosmia	NN
cord-262786-otxpc46a	135	20	in	in	IN
cord-262786-otxpc46a	135	21	these	these	DT
cord-262786-otxpc46a	135	22	patients	patient	NNS
cord-262786-otxpc46a	135	23	.	.	.
cord-262786-otxpc46a	136	1	However	however	RB
cord-262786-otxpc46a	136	2	,	,	,
cord-262786-otxpc46a	136	3	recent	recent	JJ
cord-262786-otxpc46a	136	4	imaging	imaging	NN
cord-262786-otxpc46a	136	5	studies	study	NNS
cord-262786-otxpc46a	136	6	demonstrate	demonstrate	VBP
cord-262786-otxpc46a	136	7	no	no	DT
cord-262786-otxpc46a	136	8	signs	sign	NNS
cord-262786-otxpc46a	136	9	of	of	IN
cord-262786-otxpc46a	136	10	sinusitis	sinusitis	NN
cord-262786-otxpc46a	136	11	in	in	IN
cord-262786-otxpc46a	136	12	SARS	SARS	NNP
cord-262786-otxpc46a	136	13	-	-	HYPH
cord-262786-otxpc46a	136	14	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	136	15	patients	patient	NNS
cord-262786-otxpc46a	136	16	.	.	.
cord-262786-otxpc46a	137	1	Moreover	moreover	RB
cord-262786-otxpc46a	137	2	,	,	,
cord-262786-otxpc46a	137	3	the	the	DT
cord-262786-otxpc46a	137	4	presence	presence	NN
cord-262786-otxpc46a	137	5	of	of	IN
cord-262786-otxpc46a	137	6	anosmia	anosmia	NN
cord-262786-otxpc46a	137	7	in	in	IN
cord-262786-otxpc46a	137	8	the	the	DT
cord-262786-otxpc46a	137	9	absence	absence	NN
cord-262786-otxpc46a	137	10	of	of	IN
cord-262786-otxpc46a	137	11	other	other	JJ
cord-262786-otxpc46a	137	12	symptoms	symptom	NNS
cord-262786-otxpc46a	137	13	suggests	suggest	VBZ
cord-262786-otxpc46a	137	14	that	that	IN
cord-262786-otxpc46a	137	15	coryza	coryza	NNP
cord-262786-otxpc46a	137	16	can	can	MD
cord-262786-otxpc46a	137	17	not	not	RB
cord-262786-otxpc46a	137	18	be	be	VB
cord-262786-otxpc46a	137	19	the	the	DT
cord-262786-otxpc46a	137	20	reason	reason	NN
cord-262786-otxpc46a	137	21	for	for	IN
cord-262786-otxpc46a	137	22	olfactory	olfactory	JJ
cord-262786-otxpc46a	137	23	dysfunction	dysfunction	NN
cord-262786-otxpc46a	137	24	in	in	IN
cord-262786-otxpc46a	137	25	SARS	SARS	NNP
cord-262786-otxpc46a	137	26	-	-	HYPH
cord-262786-otxpc46a	137	27	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	137	28	[	[	-LRB-
cord-262786-otxpc46a	137	29	15	15	CD
cord-262786-otxpc46a	137	30	]	]	-RRB-
cord-262786-otxpc46a	137	31	.	.	.
cord-262786-otxpc46a	138	1	Indeed	indeed	RB
cord-262786-otxpc46a	138	2	,	,	,
cord-262786-otxpc46a	138	3	milder	mild	JJR
cord-262786-otxpc46a	138	4	inflammation	inflammation	NN
cord-262786-otxpc46a	138	5	and	and	CC
cord-262786-otxpc46a	138	6	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	138	7	infiltrations	infiltration	NNS
cord-262786-otxpc46a	138	8	in	in	IN
cord-262786-otxpc46a	138	9	SARS	SARS	NNP
cord-262786-otxpc46a	138	10	-	-	HYPH
cord-262786-otxpc46a	138	11	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	138	12	infection	infection	NN
cord-262786-otxpc46a	138	13	comparing	compare	VBG
cord-262786-otxpc46a	138	14	with	with	IN
cord-262786-otxpc46a	138	15	SARS	SARS	NNP
cord-262786-otxpc46a	138	16	suggest	suggest	VBP
cord-262786-otxpc46a	138	17	a	a	DT
cord-262786-otxpc46a	138	18	different	different	JJ
cord-262786-otxpc46a	138	19	route	route	NN
cord-262786-otxpc46a	138	20	of	of	IN
cord-262786-otxpc46a	138	21	infection	infection	NN
cord-262786-otxpc46a	138	22	through	through	IN
cord-262786-otxpc46a	138	23	which	which	WDT
cord-262786-otxpc46a	138	24	the	the	DT
cord-262786-otxpc46a	138	25	virus	virus	NN
cord-262786-otxpc46a	138	26	transmits	transmit	VBZ
cord-262786-otxpc46a	138	27	via	via	IN
cord-262786-otxpc46a	138	28	infected	infected	JJ
cord-262786-otxpc46a	138	29	macrophages	macrophage	NNS
cord-262786-otxpc46a	138	30	to	to	IN
cord-262786-otxpc46a	138	31	the	the	DT
cord-262786-otxpc46a	138	32	supporting	support	VBG
cord-262786-otxpc46a	138	33	cells	cell	NNS
cord-262786-otxpc46a	138	34	of	of	IN
cord-262786-otxpc46a	138	35	the	the	DT
cord-262786-otxpc46a	138	36	olfactory	olfactory	JJ
cord-262786-otxpc46a	138	37	epithelium	epithelium	NN
cord-262786-otxpc46a	138	38	and	and	CC
cord-262786-otxpc46a	138	39	olfactory	olfactory	JJ
cord-262786-otxpc46a	138	40	bulb	bulb	NN
cord-262786-otxpc46a	138	41	,	,	,
cord-262786-otxpc46a	138	42	leading	lead	VBG
cord-262786-otxpc46a	138	43	to	to	IN
cord-262786-otxpc46a	138	44	impairment	impairment	NN
cord-262786-otxpc46a	138	45	of	of	IN
cord-262786-otxpc46a	138	46	olfactory	olfactory	JJ
cord-262786-otxpc46a	138	47	receptors	receptor	NNS
cord-262786-otxpc46a	138	48	[	[	-LRB-
cord-262786-otxpc46a	138	49	63	63	CD
cord-262786-otxpc46a	138	50	]	]	-RRB-
cord-262786-otxpc46a	138	51	.	.	.
cord-262786-otxpc46a	139	1	Several	several	JJ
cord-262786-otxpc46a	139	2	findings	finding	NNS
cord-262786-otxpc46a	139	3	support	support	VBP
cord-262786-otxpc46a	139	4	this	this	DT
cord-262786-otxpc46a	139	5	latter	latter	JJ
cord-262786-otxpc46a	139	6	hypothesis	hypothesis	NN
cord-262786-otxpc46a	139	7	:	:	:
cord-262786-otxpc46a	139	8	first	first	RB
cord-262786-otxpc46a	139	9	,	,	,
cord-262786-otxpc46a	139	10	olfactory	olfactory	JJ
cord-262786-otxpc46a	139	11	epithelial	epithelial	JJ
cord-262786-otxpc46a	139	12	cells	cell	NNS
cord-262786-otxpc46a	139	13	(	(	-LRB-
cord-262786-otxpc46a	139	14	particularly	particularly	RB
cord-262786-otxpc46a	139	15	sustentacular	sustentacular	JJ
cord-262786-otxpc46a	139	16	cells	cell	NNS
cord-262786-otxpc46a	139	17	)	)	-RRB-
cord-262786-otxpc46a	139	18	and	and	CC
cord-262786-otxpc46a	139	19	olfactory	olfactory	JJ
cord-262786-otxpc46a	139	20	bulb	bulb	NN
cord-262786-otxpc46a	139	21	cells	cell	NNS
cord-262786-otxpc46a	139	22	express	express	VBP
cord-262786-otxpc46a	139	23	ACE-2	ACE-2	NNP
cord-262786-otxpc46a	139	24	and	and	CC
cord-262786-otxpc46a	139	25	TMPRSS2	TMPRSS2	NNP
cord-262786-otxpc46a	139	26	[	[	-LRB-
cord-262786-otxpc46a	139	27	64	64	CD
cord-262786-otxpc46a	139	28	,	,	,
cord-262786-otxpc46a	139	29	65	65	CD
cord-262786-otxpc46a	139	30	]	]	-RRB-
cord-262786-otxpc46a	139	31	.	.	.
cord-262786-otxpc46a	140	1	Second	second	JJ
cord-262786-otxpc46a	140	2	,	,	,
cord-262786-otxpc46a	140	3	postmortem	postmortem	JJ
cord-262786-otxpc46a	140	4	studies	study	NNS
cord-262786-otxpc46a	140	5	show	show	VBP
cord-262786-otxpc46a	140	6	that	that	IN
cord-262786-otxpc46a	140	7	the	the	DT
cord-262786-otxpc46a	140	8	virus	virus	NN
cord-262786-otxpc46a	140	9	can	can	MD
cord-262786-otxpc46a	140	10	invade	invade	VB
cord-262786-otxpc46a	140	11	the	the	DT
cord-262786-otxpc46a	140	12	brain	brain	NN
cord-262786-otxpc46a	140	13	through	through	IN
cord-262786-otxpc46a	140	14	the	the	DT
cord-262786-otxpc46a	140	15	olfactory	olfactory	JJ
cord-262786-otxpc46a	140	16	epithelium	epithelium	NN
cord-262786-otxpc46a	140	17	and	and	CC
cord-262786-otxpc46a	140	18	olfactory	olfactory	JJ
cord-262786-otxpc46a	140	19	bulb	bulb	NN
cord-262786-otxpc46a	140	20	[	[	-LRB-
cord-262786-otxpc46a	140	21	66	66	CD
cord-262786-otxpc46a	140	22	]	]	-RRB-
cord-262786-otxpc46a	140	23	.	.	.
cord-262786-otxpc46a	141	1	Third	third	JJ
cord-262786-otxpc46a	141	2	,	,	,
cord-262786-otxpc46a	141	3	positron	positron	NN
cord-262786-otxpc46a	141	4	emission	emission	NN
cord-262786-otxpc46a	141	5	tomography	tomography	NN
cord-262786-otxpc46a	141	6	-	-	HYPH
cord-262786-otxpc46a	141	7	computed	compute	VBN
cord-262786-otxpc46a	141	8	tomography	tomography	NN
cord-262786-otxpc46a	141	9	(	(	-LRB-
cord-262786-otxpc46a	141	10	PET	PET	NNP
cord-262786-otxpc46a	141	11	-	-	HYPH
cord-262786-otxpc46a	141	12	CT	CT	NNP
cord-262786-otxpc46a	141	13	)	)	-RRB-
cord-262786-otxpc46a	141	14	study	study	NN
cord-262786-otxpc46a	141	15	in	in	IN
cord-262786-otxpc46a	141	16	SARS	SARS	NNP
cord-262786-otxpc46a	141	17	-	-	HYPH
cord-262786-otxpc46a	141	18	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	141	19	patients	patient	NNS
cord-262786-otxpc46a	141	20	with	with	IN
cord-262786-otxpc46a	141	21	anosmia	anosmia	NN
cord-262786-otxpc46a	141	22	demonstrate	demonstrate	VBP
cord-262786-otxpc46a	141	23	declined	decline	VBD
cord-262786-otxpc46a	141	24	orbitofrontal	orbitofrontal	JJ
cord-262786-otxpc46a	141	25	cortex	cortex	NN
cord-262786-otxpc46a	141	26	activity	activity	NN
cord-262786-otxpc46a	141	27	,	,	,
cord-262786-otxpc46a	141	28	suggesting	suggest	VBG
cord-262786-otxpc46a	141	29	neural	neural	JJ
cord-262786-otxpc46a	141	30	dysfunction	dysfunction	NN
cord-262786-otxpc46a	141	31	[	[	-LRB-
cord-262786-otxpc46a	141	32	67	67	CD
cord-262786-otxpc46a	141	33	]	]	-RRB-
cord-262786-otxpc46a	141	34	.	.	.
cord-262786-otxpc46a	142	1	Forth	forth	RB
cord-262786-otxpc46a	142	2	,	,	,
cord-262786-otxpc46a	142	3	the	the	DT
cord-262786-otxpc46a	142	4	genome	genome	NN
cord-262786-otxpc46a	142	5	sequence	sequence	NN
cord-262786-otxpc46a	142	6	of	of	IN
cord-262786-otxpc46a	142	7	the	the	DT
cord-262786-otxpc46a	142	8	virus	virus	NN
cord-262786-otxpc46a	142	9	was	be	VBD
cord-262786-otxpc46a	142	10	found	find	VBN
cord-262786-otxpc46a	142	11	in	in	IN
cord-262786-otxpc46a	142	12	the	the	DT
cord-262786-otxpc46a	142	13	olfactory	olfactory	JJ
cord-262786-otxpc46a	142	14	mucosa	mucosa	JJ
cord-262786-otxpc46a	142	15	and	and	CC
cord-262786-otxpc46a	142	16	olfactory	olfactory	JJ
cord-262786-otxpc46a	142	17	bulb	bulb	NN
cord-262786-otxpc46a	142	18	,	,	,
cord-262786-otxpc46a	142	19	indicating	indicate	VBG
cord-262786-otxpc46a	142	20	axonal	axonal	JJ
cord-262786-otxpc46a	142	21	transport	transport	NN
cord-262786-otxpc46a	142	22	[	[	-LRB-
cord-262786-otxpc46a	142	23	66	66	CD
cord-262786-otxpc46a	142	24	]	]	-RRB-
cord-262786-otxpc46a	142	25	.	.	.
cord-262786-otxpc46a	143	1	The	the	DT
cord-262786-otxpc46a	143	2	latter	latter	JJ
cord-262786-otxpc46a	143	3	hypothesis	hypothesis	NN
cord-262786-otxpc46a	143	4	,	,	,
cord-262786-otxpc46a	143	5	also	also	RB
cord-262786-otxpc46a	143	6	known	know	VBN
cord-262786-otxpc46a	143	7	as	as	IN
cord-262786-otxpc46a	143	8	post	post	JJ
cord-262786-otxpc46a	143	9	-	-	JJ
cord-262786-otxpc46a	143	10	viral	viral	JJ
cord-262786-otxpc46a	143	11	olfactory	olfactory	JJ
cord-262786-otxpc46a	143	12	dysfunction	dysfunction	NN
cord-262786-otxpc46a	143	13	,	,	,
cord-262786-otxpc46a	143	14	is	be	VBZ
cord-262786-otxpc46a	143	15	reported	report	VBN
cord-262786-otxpc46a	143	16	in	in	IN
cord-262786-otxpc46a	143	17	a	a	DT
cord-262786-otxpc46a	143	18	case	case	NN
cord-262786-otxpc46a	143	19	of	of	IN
cord-262786-otxpc46a	143	20	SARS	SARS	NNP
cord-262786-otxpc46a	143	21	-	-	HYPH
cord-262786-otxpc46a	143	22	CoV	CoV	NNP
cord-262786-otxpc46a	143	23	as	as	RB
cord-262786-otxpc46a	143	24	well	well	RB
cord-262786-otxpc46a	143	25	and	and	CC
cord-262786-otxpc46a	143	26	is	be	VBZ
cord-262786-otxpc46a	143	27	more	more	RBR
cord-262786-otxpc46a	143	28	prevalent	prevalent	JJ
cord-262786-otxpc46a	143	29	among	among	IN
cord-262786-otxpc46a	143	30	patients	patient	NNS
cord-262786-otxpc46a	143	31	with	with	IN
cord-262786-otxpc46a	143	32	a	a	DT
cord-262786-otxpc46a	143	33	history	history	NN
cord-262786-otxpc46a	143	34	of	of	IN
cord-262786-otxpc46a	143	35	the	the	DT
cord-262786-otxpc46a	143	36	neurologic	neurologic	JJ
cord-262786-otxpc46a	143	37	disease	disease	NN
cord-262786-otxpc46a	143	38	[	[	-LRB-
cord-262786-otxpc46a	143	39	64	64	CD
cord-262786-otxpc46a	143	40	]	]	-RRB-
cord-262786-otxpc46a	143	41	.	.	.
cord-262786-otxpc46a	144	1	Maintenance	maintenance	NN
cord-262786-otxpc46a	144	2	of	of	IN
cord-262786-otxpc46a	144	3	viral	viral	JJ
cord-262786-otxpc46a	144	4	load	load	NN
cord-262786-otxpc46a	144	5	in	in	IN
cord-262786-otxpc46a	144	6	the	the	DT
cord-262786-otxpc46a	144	7	olfactory	olfactory	JJ
cord-262786-otxpc46a	144	8	epithelium	epithelium	NN
cord-262786-otxpc46a	144	9	in	in	IN
cord-262786-otxpc46a	144	10	post	post	JJ
cord-262786-otxpc46a	144	11	-	-	JJ
cord-262786-otxpc46a	144	12	viral	viral	JJ
cord-262786-otxpc46a	144	13	olfactory	olfactory	JJ
cord-262786-otxpc46a	144	14	dysfunction	dysfunction	NN
cord-262786-otxpc46a	144	15	can	can	MD
cord-262786-otxpc46a	144	16	disrupt	disrupt	VB
cord-262786-otxpc46a	144	17	the	the	DT
cord-262786-otxpc46a	144	18	regenerative	regenerative	JJ
cord-262786-otxpc46a	144	19	capacity	capacity	NN
cord-262786-otxpc46a	144	20	of	of	IN
cord-262786-otxpc46a	144	21	neurons	neuron	NNS
cord-262786-otxpc46a	144	22	[	[	-LRB-
cord-262786-otxpc46a	144	23	64	64	CD
cord-262786-otxpc46a	144	24	]	]	-RRB-
cord-262786-otxpc46a	144	25	.	.	.
cord-262786-otxpc46a	145	1	Both	both	DT
cord-262786-otxpc46a	145	2	ischemic	ischemic	JJ
cord-262786-otxpc46a	145	3	and	and	CC
cord-262786-otxpc46a	145	4	hemorrhagic	hemorrhagic	JJ
cord-262786-otxpc46a	145	5	strokes	stroke	NNS
cord-262786-otxpc46a	145	6	are	be	VBP
cord-262786-otxpc46a	145	7	being	be	VBG
cord-262786-otxpc46a	145	8	increasingly	increasingly	RB
cord-262786-otxpc46a	145	9	reported	report	VBN
cord-262786-otxpc46a	145	10	in	in	IN
cord-262786-otxpc46a	145	11	SARS	SARS	NNP
cord-262786-otxpc46a	145	12	-	-	HYPH
cord-262786-otxpc46a	145	13	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	145	14	patients	patient	NNS
cord-262786-otxpc46a	145	15	and	and	CC
cord-262786-otxpc46a	145	16	are	be	VBP
cord-262786-otxpc46a	145	17	the	the	DT
cord-262786-otxpc46a	145	18	most	most	RBS
cord-262786-otxpc46a	145	19	common	common	JJ
cord-262786-otxpc46a	145	20	findings	finding	NNS
cord-262786-otxpc46a	145	21	in	in	IN
cord-262786-otxpc46a	145	22	neuroimaging	neuroimage	VBG
cord-262786-otxpc46a	145	23	studies	study	NNS
cord-262786-otxpc46a	145	24	(	(	-LRB-
cord-262786-otxpc46a	145	25	Table	table	NN
cord-262786-otxpc46a	145	26	2	2	CD
cord-262786-otxpc46a	145	27	)	)	-RRB-
cord-262786-otxpc46a	145	28	[	[	-LRB-
cord-262786-otxpc46a	145	29	40	40	CD
cord-262786-otxpc46a	145	30	,	,	,
cord-262786-otxpc46a	145	31	75	75	CD
cord-262786-otxpc46a	145	32	]	]	-RRB-
cord-262786-otxpc46a	145	33	.	.	.
cord-262786-otxpc46a	146	1	The	the	DT
cord-262786-otxpc46a	146	2	prevalence	prevalence	NN
cord-262786-otxpc46a	146	3	of	of	IN
cord-262786-otxpc46a	146	4	stroke	stroke	NN
cord-262786-otxpc46a	146	5	is	be	VBZ
cord-262786-otxpc46a	146	6	estimated	estimate	VBN
cord-262786-otxpc46a	146	7	to	to	TO
cord-262786-otxpc46a	146	8	be	be	VB
cord-262786-otxpc46a	146	9	between	between	IN
cord-262786-otxpc46a	146	10	0.2	0.2	CD
cord-262786-otxpc46a	146	11	and	and	CC
cord-262786-otxpc46a	146	12	1	1	CD
cord-262786-otxpc46a	146	13	%	%	NN
cord-262786-otxpc46a	146	14	of	of	IN
cord-262786-otxpc46a	146	15	all	all	DT
cord-262786-otxpc46a	146	16	infected	infect	VBN
cord-262786-otxpc46a	146	17	patients	patient	NNS
cord-262786-otxpc46a	146	18	[	[	-LRB-
cord-262786-otxpc46a	146	19	76	76	CD
cord-262786-otxpc46a	146	20	]	]	-RRB-
cord-262786-otxpc46a	146	21	,	,	,
cord-262786-otxpc46a	146	22	often	often	RB
cord-262786-otxpc46a	146	23	proposed	propose	VBD
cord-262786-otxpc46a	146	24	as	as	IN
cord-262786-otxpc46a	146	25	the	the	DT
cord-262786-otxpc46a	146	26	most	most	RBS
cord-262786-otxpc46a	146	27	common	common	JJ
cord-262786-otxpc46a	146	28	neurologic	neurologic	JJ
cord-262786-otxpc46a	146	29	manifestation	manifestation	NN
cord-262786-otxpc46a	146	30	in	in	IN
cord-262786-otxpc46a	146	31	SARS	SARS	NNP
cord-262786-otxpc46a	146	32	-	-	HYPH
cord-262786-otxpc46a	146	33	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	146	34	patients	patient	NNS
cord-262786-otxpc46a	146	35	[	[	-LRB-
cord-262786-otxpc46a	146	36	77	77	CD
cord-262786-otxpc46a	146	37	]	]	-RRB-
cord-262786-otxpc46a	146	38	.	.	.
cord-262786-otxpc46a	147	1	High	high	JJ
cord-262786-otxpc46a	147	2	incidence	incidence	NN
cord-262786-otxpc46a	147	3	of	of	IN
cord-262786-otxpc46a	147	4	stroke	stroke	NN
cord-262786-otxpc46a	147	5	in	in	IN
cord-262786-otxpc46a	147	6	SARS	SARS	NNP
cord-262786-otxpc46a	147	7	-	-	HYPH
cord-262786-otxpc46a	147	8	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	147	9	patients	patient	NNS
cord-262786-otxpc46a	147	10	under	under	IN
cord-262786-otxpc46a	147	11	50	50	CD
cord-262786-otxpc46a	147	12	years	year	NNS
cord-262786-otxpc46a	147	13	old	old	JJ
cord-262786-otxpc46a	147	14	without	without	IN
cord-262786-otxpc46a	147	15	cardiovascular	cardiovascular	JJ
cord-262786-otxpc46a	147	16	risk	risk	NN
cord-262786-otxpc46a	147	17	factors	factor	NNS
cord-262786-otxpc46a	147	18	accompanied	accompany	VBN
cord-262786-otxpc46a	147	19	by	by	IN
cord-262786-otxpc46a	147	20	worse	bad	JJR
cord-262786-otxpc46a	147	21	outcomes	outcome	NNS
cord-262786-otxpc46a	147	22	in	in	IN
cord-262786-otxpc46a	147	23	SARS	SARS	NNP
cord-262786-otxpc46a	147	24	-	-	HYPH
cord-262786-otxpc46a	147	25	CoV-2-mediated	cov-2-mediate	VBN
cord-262786-otxpc46a	147	26	stroke	stroke	NN
cord-262786-otxpc46a	147	27	comparing	compare	VBG
cord-262786-otxpc46a	147	28	with	with	IN
cord-262786-otxpc46a	147	29	other	other	JJ
cord-262786-otxpc46a	147	30	strokes	stroke	NNS
cord-262786-otxpc46a	147	31	indicates	indicate	VBZ
cord-262786-otxpc46a	147	32	that	that	IN
cord-262786-otxpc46a	147	33	this	this	DT
cord-262786-otxpc46a	147	34	viral	viral	JJ
cord-262786-otxpc46a	147	35	infection	infection	NN
cord-262786-otxpc46a	147	36	precipitates	precipitate	VBZ
cord-262786-otxpc46a	147	37	the	the	DT
cord-262786-otxpc46a	147	38	pathways	pathway	NNS
cord-262786-otxpc46a	147	39	leading	lead	VBG
cord-262786-otxpc46a	147	40	to	to	IN
cord-262786-otxpc46a	147	41	stroke	stroke	VB
cord-262786-otxpc46a	147	42	[	[	-LRB-
cord-262786-otxpc46a	147	43	76	76	CD
cord-262786-otxpc46a	147	44	]	]	-RRB-
cord-262786-otxpc46a	147	45	.	.	.
cord-262786-otxpc46a	148	1	Postmortem	postmortem	JJ
cord-262786-otxpc46a	148	2	autopsy	autopsy	JJ
cord-262786-otxpc46a	148	3	studies	study	NNS
cord-262786-otxpc46a	148	4	of	of	IN
cord-262786-otxpc46a	148	5	SARS	SARS	NNP
cord-262786-otxpc46a	148	6	-	-	HYPH
cord-262786-otxpc46a	148	7	CoV-2-mediated	cov-2-mediate	VBN
cord-262786-otxpc46a	148	8	stroke	stroke	NN
cord-262786-otxpc46a	148	9	demonstrate	demonstrate	VBP
cord-262786-otxpc46a	148	10	hyperemic	hyperemic	JJ
cord-262786-otxpc46a	148	11	and	and	CC
cord-262786-otxpc46a	148	12	edematous	edematous	JJ
cord-262786-otxpc46a	148	13	brain	brain	NN
cord-262786-otxpc46a	148	14	areas	area	NNS
cord-262786-otxpc46a	148	15	[	[	-LRB-
cord-262786-otxpc46a	148	16	76	76	CD
cord-262786-otxpc46a	148	17	]	]	-RRB-
cord-262786-otxpc46a	148	18	.	.	.
cord-262786-otxpc46a	149	1	Also	also	RB
cord-262786-otxpc46a	149	2	,	,	,
cord-262786-otxpc46a	149	3	micro	micro	JJ
cord-262786-otxpc46a	149	4	-	-	:
cord-262786-otxpc46a	149	5	and	and	CC
cord-262786-otxpc46a	149	6	macrothrombosis	macrothrombosis	NN
cord-262786-otxpc46a	149	7	are	be	VBP
cord-262786-otxpc46a	149	8	found	find	VBN
cord-262786-otxpc46a	149	9	in	in	IN
cord-262786-otxpc46a	149	10	other	other	JJ
cord-262786-otxpc46a	149	11	organs	organ	NNS
cord-262786-otxpc46a	149	12	such	such	JJ
cord-262786-otxpc46a	149	13	as	as	IN
cord-262786-otxpc46a	149	14	lung	lung	NN
cord-262786-otxpc46a	149	15	and	and	CC
cord-262786-otxpc46a	149	16	kidney	kidney	NN
cord-262786-otxpc46a	149	17	[	[	-LRB-
cord-262786-otxpc46a	149	18	76	76	CD
cord-262786-otxpc46a	149	19	]	]	-RRB-
cord-262786-otxpc46a	149	20	.	.	.
cord-262786-otxpc46a	150	1	These	these	DT
cord-262786-otxpc46a	150	2	findings	finding	NNS
cord-262786-otxpc46a	150	3	indicate	indicate	VBP
cord-262786-otxpc46a	150	4	that	that	IN
cord-262786-otxpc46a	150	5	coagulopathy	coagulopathy	NN
cord-262786-otxpc46a	150	6	may	may	MD
cord-262786-otxpc46a	150	7	underlie	underlie	VB
cord-262786-otxpc46a	150	8	the	the	DT
cord-262786-otxpc46a	150	9	occurrence	occurrence	NN
cord-262786-otxpc46a	150	10	of	of	IN
cord-262786-otxpc46a	150	11	stroke	stroke	NN
cord-262786-otxpc46a	150	12	in	in	IN
cord-262786-otxpc46a	150	13	these	these	DT
cord-262786-otxpc46a	150	14	patients	patient	NNS
cord-262786-otxpc46a	150	15	.	.	.
cord-262786-otxpc46a	151	1	Severe	severe	JJ
cord-262786-otxpc46a	151	2	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	151	3	response	response	NN
cord-262786-otxpc46a	151	4	mediated	mediate	VBN
cord-262786-otxpc46a	151	5	by	by	IN
cord-262786-otxpc46a	151	6	SARS	SARS	NNP
cord-262786-otxpc46a	151	7	-	-	HYPH
cord-262786-otxpc46a	151	8	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	151	9	can	can	MD
cord-262786-otxpc46a	151	10	upregulate	upregulate	VB
cord-262786-otxpc46a	151	11	pro	pro	JJ
cord-262786-otxpc46a	151	12	-	-	JJ
cord-262786-otxpc46a	151	13	coagulative	coagulative	JJ
cord-262786-otxpc46a	151	14	factors	factor	NNS
cord-262786-otxpc46a	151	15	[	[	-LRB-
cord-262786-otxpc46a	151	16	17	17	CD
cord-262786-otxpc46a	151	17	]	]	-RRB-
cord-262786-otxpc46a	151	18	.	.	.
cord-262786-otxpc46a	152	1	Recent	recent	JJ
cord-262786-otxpc46a	152	2	investigations	investigation	NNS
cord-262786-otxpc46a	152	3	suggest	suggest	VBP
cord-262786-otxpc46a	152	4	that	that	IN
cord-262786-otxpc46a	152	5	blood	blood	NN
cord-262786-otxpc46a	152	6	D	d	NN
cord-262786-otxpc46a	152	7	-	-	HYPH
cord-262786-otxpc46a	152	8	dimer	dimer	NN
cord-262786-otxpc46a	152	9	,	,	,
cord-262786-otxpc46a	152	10	CRP	CRP	NNP
cord-262786-otxpc46a	152	11	,	,	,
cord-262786-otxpc46a	152	12	fibrinogen	fibrinogen	NN
cord-262786-otxpc46a	152	13	,	,	,
cord-262786-otxpc46a	152	14	and	and	CC
cord-262786-otxpc46a	152	15	WBC	WBC	NNP
cord-262786-otxpc46a	152	16	count	count	NN
cord-262786-otxpc46a	152	17	increases	increase	NNS
cord-262786-otxpc46a	152	18	in	in	IN
cord-262786-otxpc46a	152	19	SARS	SARS	NNP
cord-262786-otxpc46a	152	20	-	-	HYPH
cord-262786-otxpc46a	152	21	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	152	22	patients	patient	NNS
cord-262786-otxpc46a	152	23	,	,	,
cord-262786-otxpc46a	152	24	which	which	WDT
cord-262786-otxpc46a	152	25	propagate	propagate	VBP
cord-262786-otxpc46a	152	26	the	the	DT
cord-262786-otxpc46a	152	27	hypercoagulable	hypercoagulable	JJ
cord-262786-otxpc46a	152	28	state	state	NN
cord-262786-otxpc46a	152	29	.	.	.
cord-262786-otxpc46a	153	1	Moreover	moreover	RB
cord-262786-otxpc46a	153	2	,	,	,
cord-262786-otxpc46a	153	3	a	a	DT
cord-262786-otxpc46a	153	4	group	group	NN
cord-262786-otxpc46a	153	5	of	of	IN
cord-262786-otxpc46a	153	6	SARS	SARS	NNP
cord-262786-otxpc46a	153	7	-	-	HYPH
cord-262786-otxpc46a	153	8	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	153	9	patients	patient	NNS
cord-262786-otxpc46a	153	10	present	present	VBP
cord-262786-otxpc46a	153	11	positive	positive	JJ
cord-262786-otxpc46a	153	12	lupus	lupus	NN
cord-262786-otxpc46a	153	13	anticoagulant	anticoagulant	NN
cord-262786-otxpc46a	153	14	,	,	,
cord-262786-otxpc46a	153	15	anti	anti	NNS
cord-262786-otxpc46a	153	16	-	-	JJ
cord-262786-otxpc46a	153	17	β2-glycoprotein-1	β2-glycoprotein-1	XX
cord-262786-otxpc46a	153	18	,	,	,
cord-262786-otxpc46a	153	19	and	and	CC
cord-262786-otxpc46a	153	20	anticardiolipin	anticardiolipin	NNP
cord-262786-otxpc46a	153	21	(	(	-LRB-
cord-262786-otxpc46a	153	22	marker	marker	NN
cord-262786-otxpc46a	153	23	of	of	IN
cord-262786-otxpc46a	153	24	antiphospholipid	antiphospholipid	NNP
cord-262786-otxpc46a	153	25	syndrome	syndrome	NN
cord-262786-otxpc46a	153	26	)	)	-RRB-
cord-262786-otxpc46a	153	27	antibodies	antibody	NNS
cord-262786-otxpc46a	153	28	,	,	,
cord-262786-otxpc46a	153	29	which	which	WDT
cord-262786-otxpc46a	153	30	may	may	MD
cord-262786-otxpc46a	153	31	precipitate	precipitate	VB
cord-262786-otxpc46a	153	32	stroke	stroke	NN
cord-262786-otxpc46a	153	33	[	[	-LRB-
cord-262786-otxpc46a	153	34	15	15	CD
cord-262786-otxpc46a	153	35	]	]	-RRB-
cord-262786-otxpc46a	153	36	.	.	.
cord-262786-otxpc46a	154	1	Another	another	DT
cord-262786-otxpc46a	154	2	key	key	JJ
cord-262786-otxpc46a	154	3	contributor	contributor	NN
cord-262786-otxpc46a	154	4	to	to	IN
cord-262786-otxpc46a	154	5	stroke	stroke	NN
cord-262786-otxpc46a	154	6	is	be	VBZ
cord-262786-otxpc46a	154	7	the	the	DT
cord-262786-otxpc46a	154	8	vascular	vascular	JJ
cord-262786-otxpc46a	154	9	wall	wall	NN
cord-262786-otxpc46a	154	10	injury	injury	NN
cord-262786-otxpc46a	154	11	,	,	,
cord-262786-otxpc46a	154	12	which	which	WDT
cord-262786-otxpc46a	154	13	induces	induce	VBZ
cord-262786-otxpc46a	154	14	the	the	DT
cord-262786-otxpc46a	154	15	release	release	NN
cord-262786-otxpc46a	154	16	of	of	IN
cord-262786-otxpc46a	154	17	tissue	tissue	NN
cord-262786-otxpc46a	154	18	factor	factor	NN
cord-262786-otxpc46a	154	19	[	[	-LRB-
cord-262786-otxpc46a	154	20	17	17	CD
cord-262786-otxpc46a	154	21	]	]	-RRB-
cord-262786-otxpc46a	154	22	.	.	.
cord-262786-otxpc46a	155	1	Damage	damage	NN
cord-262786-otxpc46a	155	2	to	to	IN
cord-262786-otxpc46a	155	3	vascular	vascular	JJ
cord-262786-otxpc46a	155	4	walls	wall	NNS
cord-262786-otxpc46a	155	5	may	may	MD
cord-262786-otxpc46a	155	6	occur	occur	VB
cord-262786-otxpc46a	155	7	as	as	IN
cord-262786-otxpc46a	155	8	a	a	DT
cord-262786-otxpc46a	155	9	consequence	consequence	NN
cord-262786-otxpc46a	155	10	of	of	IN
cord-262786-otxpc46a	155	11	direct	direct	JJ
cord-262786-otxpc46a	155	12	viral	viral	JJ
cord-262786-otxpc46a	155	13	invasion	invasion	NN
cord-262786-otxpc46a	155	14	and	and	CC
cord-262786-otxpc46a	155	15	replication	replication	NN
cord-262786-otxpc46a	155	16	in	in	IN
cord-262786-otxpc46a	155	17	the	the	DT
cord-262786-otxpc46a	155	18	vascular	vascular	JJ
cord-262786-otxpc46a	155	19	epithelium	epithelium	NN
cord-262786-otxpc46a	155	20	,	,	,
cord-262786-otxpc46a	155	21	also	also	RB
cord-262786-otxpc46a	155	22	known	know	VBN
cord-262786-otxpc46a	155	23	as	as	IN
cord-262786-otxpc46a	155	24	endotheliitis	endotheliitis	NNP
cord-262786-otxpc46a	155	25	[	[	-LRB-
cord-262786-otxpc46a	155	26	66	66	CD
cord-262786-otxpc46a	155	27	]	]	-RRB-
cord-262786-otxpc46a	155	28	.	.	.
cord-262786-otxpc46a	156	1	Endotheliitis	endotheliitis	NN
cord-262786-otxpc46a	156	2	due	due	JJ
cord-262786-otxpc46a	156	3	to	to	IN
cord-262786-otxpc46a	156	4	SARS	SARS	NNP
cord-262786-otxpc46a	156	5	-	-	HYPH
cord-262786-otxpc46a	156	6	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	156	7	is	be	VBZ
cord-262786-otxpc46a	156	8	reported	report	VBN
cord-262786-otxpc46a	156	9	in	in	IN
cord-262786-otxpc46a	156	10	other	other	JJ
cord-262786-otxpc46a	156	11	organs	organ	NNS
cord-262786-otxpc46a	156	12	such	such	JJ
cord-262786-otxpc46a	156	13	as	as	IN
cord-262786-otxpc46a	156	14	lung	lung	NN
cord-262786-otxpc46a	156	15	,	,	,
cord-262786-otxpc46a	156	16	heart	heart	NN
cord-262786-otxpc46a	156	17	,	,	,
cord-262786-otxpc46a	156	18	kidney	kidney	NN
cord-262786-otxpc46a	156	19	,	,	,
cord-262786-otxpc46a	156	20	and	and	CC
cord-262786-otxpc46a	156	21	bowel	bowel	NN
cord-262786-otxpc46a	156	22	but	but	CC
cord-262786-otxpc46a	156	23	not	not	RB
cord-262786-otxpc46a	156	24	yet	yet	RB
cord-262786-otxpc46a	156	25	investigated	investigate	VBN
cord-262786-otxpc46a	156	26	in	in	IN
cord-262786-otxpc46a	156	27	CNS	CNS	NNP
cord-262786-otxpc46a	156	28	[	[	-LRB-
cord-262786-otxpc46a	156	29	15	15	CD
cord-262786-otxpc46a	156	30	]	]	-RRB-
cord-262786-otxpc46a	156	31	.	.	.
cord-262786-otxpc46a	157	1	Also	also	RB
cord-262786-otxpc46a	157	2	,	,	,
cord-262786-otxpc46a	157	3	the	the	DT
cord-262786-otxpc46a	157	4	aberrant	aberrant	JJ
cord-262786-otxpc46a	157	5	immune	immune	JJ
cord-262786-otxpc46a	157	6	response	response	NN
cord-262786-otxpc46a	157	7	mediated	mediate	VBN
cord-262786-otxpc46a	157	8	by	by	IN
cord-262786-otxpc46a	157	9	SARS	SARS	NNP
cord-262786-otxpc46a	157	10	-	-	HYPH
cord-262786-otxpc46a	157	11	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	157	12	may	may	MD
cord-262786-otxpc46a	157	13	provide	provide	VB
cord-262786-otxpc46a	157	14	the	the	DT
cord-262786-otxpc46a	157	15	driving	drive	VBG
cord-262786-otxpc46a	157	16	force	force	NN
cord-262786-otxpc46a	157	17	for	for	IN
cord-262786-otxpc46a	157	18	vascular	vascular	JJ
cord-262786-otxpc46a	157	19	wall	wall	NN
cord-262786-otxpc46a	157	20	damage	damage	NN
cord-262786-otxpc46a	157	21	[	[	-LRB-
cord-262786-otxpc46a	157	22	23	23	CD
cord-262786-otxpc46a	157	23	]	]	-RRB-
cord-262786-otxpc46a	157	24	.	.	.
cord-262786-otxpc46a	158	1	This	this	DT
cord-262786-otxpc46a	158	2	process	process	NN
cord-262786-otxpc46a	158	3	takes	take	VBZ
cord-262786-otxpc46a	158	4	place	place	NN
cord-262786-otxpc46a	158	5	as	as	IN
cord-262786-otxpc46a	158	6	a	a	DT
cord-262786-otxpc46a	158	7	component	component	NN
cord-262786-otxpc46a	158	8	of	of	IN
cord-262786-otxpc46a	158	9	secondary	secondary	JJ
cord-262786-otxpc46a	158	10	hemophagocytic	hemophagocytic	JJ
cord-262786-otxpc46a	158	11	lymphohistiocytosis	lymphohistiocytosis	NNP
cord-262786-otxpc46a	158	12	,	,	,
cord-262786-otxpc46a	158	13	characterized	characterize	VBN
cord-262786-otxpc46a	158	14	by	by	IN
cord-262786-otxpc46a	158	15	inflammatory	inflammatory	NN
cord-262786-otxpc46a	158	16	-	-	HYPH
cord-262786-otxpc46a	158	17	mediated	mediate	VBN
cord-262786-otxpc46a	158	18	tissue	tissue	NN
cord-262786-otxpc46a	158	19	damage	damage	NN
cord-262786-otxpc46a	158	20	through	through	IN
cord-262786-otxpc46a	158	21	hyperactivation	hyperactivation	NN
cord-262786-otxpc46a	158	22	of	of	IN
cord-262786-otxpc46a	158	23	macrophages	macrophage	NNS
cord-262786-otxpc46a	158	24	and	and	CC
cord-262786-otxpc46a	158	25	lymphocytes	lymphocyte	NNS
cord-262786-otxpc46a	158	26	,	,	,
cord-262786-otxpc46a	158	27	leading	lead	VBG
cord-262786-otxpc46a	158	28	to	to	IN
cord-262786-otxpc46a	158	29	microangiopathy	microangiopathy	NNP
cord-262786-otxpc46a	158	30	[	[	-LRB-
cord-262786-otxpc46a	158	31	15	15	CD
cord-262786-otxpc46a	158	32	]	]	-RRB-
cord-262786-otxpc46a	158	33	.	.	.
cord-262786-otxpc46a	159	1	Several	several	JJ
cord-262786-otxpc46a	159	2	other	other	JJ
cord-262786-otxpc46a	159	3	mechanisms	mechanism	NNS
cord-262786-otxpc46a	159	4	may	may	MD
cord-262786-otxpc46a	159	5	increase	increase	VB
cord-262786-otxpc46a	159	6	the	the	DT
cord-262786-otxpc46a	159	7	risk	risk	NN
cord-262786-otxpc46a	159	8	of	of	IN
cord-262786-otxpc46a	159	9	stroke	stroke	NN
cord-262786-otxpc46a	159	10	in	in	IN
cord-262786-otxpc46a	159	11	SARS	SARS	NNP
cord-262786-otxpc46a	159	12	-	-	HYPH
cord-262786-otxpc46a	159	13	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	159	14	infection	infection	NN
cord-262786-otxpc46a	159	15	.	.	.
cord-262786-otxpc46a	160	1	The	the	DT
cord-262786-otxpc46a	160	2	cytokine	cytokine	NN
cord-262786-otxpc46a	160	3	storm	storm	NN
cord-262786-otxpc46a	160	4	mediated	mediate	VBN
cord-262786-otxpc46a	160	5	by	by	IN
cord-262786-otxpc46a	160	6	SARS	SARS	NNP
cord-262786-otxpc46a	160	7	-	-	HYPH
cord-262786-otxpc46a	160	8	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	160	9	precipitates	precipitate	VBZ
cord-262786-otxpc46a	160	10	microthrombosis	microthrombosis	NN
cord-262786-otxpc46a	160	11	[	[	-LRB-
cord-262786-otxpc46a	160	12	41	41	CD
cord-262786-otxpc46a	160	13	]	]	-RRB-
cord-262786-otxpc46a	160	14	.	.	.
cord-262786-otxpc46a	161	1	In	in	IN
cord-262786-otxpc46a	161	2	fact	fact	NN
cord-262786-otxpc46a	161	3	,	,	,
cord-262786-otxpc46a	161	4	elevated	elevated	JJ
cord-262786-otxpc46a	161	5	expression	expression	NN
cord-262786-otxpc46a	161	6	of	of	IN
cord-262786-otxpc46a	161	7	pro	pro	JJ
cord-262786-otxpc46a	161	8	-	-	JJ
cord-262786-otxpc46a	161	9	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	161	10	cytokines	cytokine	NNS
cord-262786-otxpc46a	161	11	(	(	-LRB-
cord-262786-otxpc46a	161	12	namely	namely	RB
cord-262786-otxpc46a	161	13	IL-1β	IL-1β	NNP
cord-262786-otxpc46a	161	14	,	,	,
cord-262786-otxpc46a	161	15	IL-6	IL-6	NNP
cord-262786-otxpc46a	161	16	,	,	,
cord-262786-otxpc46a	161	17	and	and	CC
cord-262786-otxpc46a	161	18	TNF	TNF	NNP
cord-262786-otxpc46a	161	19	-	-	HYPH
cord-262786-otxpc46a	161	20	α	α	NNP
cord-262786-otxpc46a	161	21	)	)	-RRB-
cord-262786-otxpc46a	161	22	increases	increase	VBZ
cord-262786-otxpc46a	161	23	the	the	DT
cord-262786-otxpc46a	161	24	risk	risk	NN
cord-262786-otxpc46a	161	25	of	of	IN
cord-262786-otxpc46a	161	26	ischemic	ischemic	JJ
cord-262786-otxpc46a	161	27	and	and	CC
cord-262786-otxpc46a	161	28	hemorrhagic	hemorrhagic	JJ
cord-262786-otxpc46a	161	29	strokes	stroke	NNS
cord-262786-otxpc46a	161	30	[	[	-LRB-
cord-262786-otxpc46a	161	31	78	78	CD
cord-262786-otxpc46a	161	32	]	]	-RRB-
cord-262786-otxpc46a	161	33	.	.	.
cord-262786-otxpc46a	162	1	Also	also	RB
cord-262786-otxpc46a	162	2	,	,	,
cord-262786-otxpc46a	162	3	anti	anti	JJ
cord-262786-otxpc46a	162	4	-	-	JJ
cord-262786-otxpc46a	162	5	cytokine	cytokine	JJ
cord-262786-otxpc46a	162	6	therapies	therapy	NNS
cord-262786-otxpc46a	162	7	against	against	IN
cord-262786-otxpc46a	162	8	these	these	DT
cord-262786-otxpc46a	162	9	mediators	mediator	NNS
cord-262786-otxpc46a	162	10	protect	protect	VBP
cord-262786-otxpc46a	162	11	from	from	IN
cord-262786-otxpc46a	162	12	recurrence	recurrence	NN
cord-262786-otxpc46a	162	13	of	of	IN
cord-262786-otxpc46a	162	14	stroke	stroke	NN
cord-262786-otxpc46a	162	15	in	in	IN
cord-262786-otxpc46a	162	16	experimental	experimental	JJ
cord-262786-otxpc46a	162	17	models	model	NNS
cord-262786-otxpc46a	162	18	[	[	-LRB-
cord-262786-otxpc46a	162	19	78	78	CD
cord-262786-otxpc46a	162	20	]	]	-RRB-
cord-262786-otxpc46a	162	21	.	.	.
cord-262786-otxpc46a	163	1	Moreover	moreover	RB
cord-262786-otxpc46a	163	2	,	,	,
cord-262786-otxpc46a	163	3	systemic	systemic	JJ
cord-262786-otxpc46a	163	4	inflammation	inflammation	NN
cord-262786-otxpc46a	163	5	can	can	MD
cord-262786-otxpc46a	163	6	ignite	ignite	VB
cord-262786-otxpc46a	163	7	atrial	atrial	JJ
cord-262786-otxpc46a	163	8	fibrillation	fibrillation	NN
cord-262786-otxpc46a	163	9	and	and	CC
cord-262786-otxpc46a	163	10	rupture	rupture	VB
cord-262786-otxpc46a	163	11	the	the	DT
cord-262786-otxpc46a	163	12	carotid	carotid	JJ
cord-262786-otxpc46a	163	13	plaques	plaque	NNS
cord-262786-otxpc46a	163	14	,	,	,
cord-262786-otxpc46a	163	15	leading	lead	VBG
cord-262786-otxpc46a	163	16	to	to	IN
cord-262786-otxpc46a	163	17	ischemic	ischemic	JJ
cord-262786-otxpc46a	163	18	stroke	stroke	NN
cord-262786-otxpc46a	163	19	[	[	-LRB-
cord-262786-otxpc46a	163	20	15	15	CD
cord-262786-otxpc46a	163	21	]	]	-RRB-
cord-262786-otxpc46a	163	22	.	.	.
cord-262786-otxpc46a	164	1	Also	also	RB
cord-262786-otxpc46a	164	2	,	,	,
cord-262786-otxpc46a	164	3	SARS	SARS	NNP
cord-262786-otxpc46a	164	4	-	-	HYPH
cord-262786-otxpc46a	164	5	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	164	6	downregulates	downregulate	VBZ
cord-262786-otxpc46a	164	7	the	the	DT
cord-262786-otxpc46a	164	8	expression	expression	NN
cord-262786-otxpc46a	164	9	of	of	IN
cord-262786-otxpc46a	164	10	ACE-2	ACE-2	NNP
cord-262786-otxpc46a	164	11	receptors	receptor	NNS
cord-262786-otxpc46a	164	12	,	,	,
cord-262786-otxpc46a	164	13	which	which	WDT
cord-262786-otxpc46a	164	14	degrade	degrade	VBP
cord-262786-otxpc46a	164	15	angiotensin	angiotensin	NN
cord-262786-otxpc46a	164	16	II	II	NNP
cord-262786-otxpc46a	164	17	.	.	.
cord-262786-otxpc46a	165	1	So	so	RB
cord-262786-otxpc46a	165	2	,	,	,
cord-262786-otxpc46a	165	3	the	the	DT
cord-262786-otxpc46a	165	4	increase	increase	NN
cord-262786-otxpc46a	165	5	in	in	IN
cord-262786-otxpc46a	165	6	angiotensin	angiotensin	NN
cord-262786-otxpc46a	165	7	II	II	NNP
cord-262786-otxpc46a	165	8	and	and	CC
cord-262786-otxpc46a	165	9	the	the	DT
cord-262786-otxpc46a	165	10	resulting	result	VBG
cord-262786-otxpc46a	165	11	activation	activation	NN
cord-262786-otxpc46a	165	12	of	of	IN
cord-262786-otxpc46a	165	13	the	the	DT
cord-262786-otxpc46a	165	14	renin	renin	NN
cord-262786-otxpc46a	165	15	-	-	HYPH
cord-262786-otxpc46a	165	16	angiotensin	angiotensin	NN
cord-262786-otxpc46a	165	17	-	-	HYPH
cord-262786-otxpc46a	165	18	aldosterone	aldosterone	NN
cord-262786-otxpc46a	165	19	system	system	NN
cord-262786-otxpc46a	165	20	(	(	-LRB-
cord-262786-otxpc46a	165	21	RAAS	RAAS	NNP
cord-262786-otxpc46a	165	22	)	)	-RRB-
cord-262786-otxpc46a	165	23	system	system	NN
cord-262786-otxpc46a	165	24	promotes	promote	VBZ
cord-262786-otxpc46a	165	25	sympathetic	sympathetic	JJ
cord-262786-otxpc46a	165	26	tone	tone	NN
cord-262786-otxpc46a	165	27	,	,	,
cord-262786-otxpc46a	165	28	oxidative	oxidative	JJ
cord-262786-otxpc46a	165	29	stress	stress	NN
cord-262786-otxpc46a	165	30	,	,	,
cord-262786-otxpc46a	165	31	and	and	CC
cord-262786-otxpc46a	165	32	inflammation	inflammation	NN
cord-262786-otxpc46a	165	33	and	and	CC
cord-262786-otxpc46a	165	34	triggers	trigger	VBZ
cord-262786-otxpc46a	165	35	fibrotic	fibrotic	JJ
cord-262786-otxpc46a	165	36	events	event	NNS
cord-262786-otxpc46a	165	37	[	[	-LRB-
cord-262786-otxpc46a	165	38	79	79	CD
cord-262786-otxpc46a	165	39	]	]	-RRB-
cord-262786-otxpc46a	165	40	.	.	.
cord-262786-otxpc46a	166	1	Multiple	multiple	JJ
cord-262786-otxpc46a	166	2	sclerosis	sclerosis	NN
cord-262786-otxpc46a	166	3	(	(	-LRB-
cord-262786-otxpc46a	166	4	MS	MS	NNP
cord-262786-otxpc46a	166	5	)	)	-RRB-
cord-262786-otxpc46a	166	6	is	be	VBZ
cord-262786-otxpc46a	166	7	a	a	DT
cord-262786-otxpc46a	166	8	chronic	chronic	JJ
cord-262786-otxpc46a	166	9	disabling	disable	VBG
cord-262786-otxpc46a	166	10	disorder	disorder	NN
cord-262786-otxpc46a	166	11	characterized	characterize	VBN
cord-262786-otxpc46a	166	12	by	by	IN
cord-262786-otxpc46a	166	13	demyelination	demyelination	NN
cord-262786-otxpc46a	166	14	of	of	IN
cord-262786-otxpc46a	166	15	white	white	JJ
cord-262786-otxpc46a	166	16	matter	matter	NN
cord-262786-otxpc46a	166	17	and	and	CC
cord-262786-otxpc46a	166	18	,	,	,
cord-262786-otxpc46a	166	19	to	to	IN
cord-262786-otxpc46a	166	20	a	a	DT
cord-262786-otxpc46a	166	21	lesser	less	JJR
cord-262786-otxpc46a	166	22	extent	extent	NN
cord-262786-otxpc46a	166	23	,	,	,
cord-262786-otxpc46a	166	24	gray	gray	JJ
cord-262786-otxpc46a	166	25	matter	matter	NN
cord-262786-otxpc46a	166	26	of	of	IN
cord-262786-otxpc46a	166	27	CNS	CNS	NNP
cord-262786-otxpc46a	166	28	[	[	-LRB-
cord-262786-otxpc46a	166	29	51	51	CD
cord-262786-otxpc46a	166	30	]	]	-RRB-
cord-262786-otxpc46a	166	31	.	.	.
cord-262786-otxpc46a	167	1	Recently	recently	RB
cord-262786-otxpc46a	167	2	,	,	,
cord-262786-otxpc46a	167	3	the	the	DT
cord-262786-otxpc46a	167	4	first	first	JJ
cord-262786-otxpc46a	167	5	casereport	casereport	NN
cord-262786-otxpc46a	167	6	of	of	IN
cord-262786-otxpc46a	167	7	MS	MS	NNP
cord-262786-otxpc46a	167	8	after	after	IN
cord-262786-otxpc46a	167	9	SARS	SARS	NNP
cord-262786-otxpc46a	167	10	-	-	HYPH
cord-262786-otxpc46a	167	11	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	167	12	infection	infection	NN
cord-262786-otxpc46a	167	13	was	be	VBD
cord-262786-otxpc46a	167	14	presented	present	VBN
cord-262786-otxpc46a	167	15	in	in	IN
cord-262786-otxpc46a	167	16	the	the	DT
cord-262786-otxpc46a	167	17	literature	literature	NN
cord-262786-otxpc46a	167	18	[	[	-LRB-
cord-262786-otxpc46a	167	19	80	80	CD
cord-262786-otxpc46a	167	20	]	]	-RRB-
cord-262786-otxpc46a	167	21	.	.	.
cord-262786-otxpc46a	168	1	A	a	DT
cord-262786-otxpc46a	168	2	SARS	SARS	NNP
cord-262786-otxpc46a	168	3	-	-	HYPH
cord-262786-otxpc46a	168	4	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	168	5	patient	patient	NN
cord-262786-otxpc46a	168	6	without	without	IN
cord-262786-otxpc46a	168	7	a	a	DT
cord-262786-otxpc46a	168	8	history	history	NN
cord-262786-otxpc46a	168	9	of	of	IN
cord-262786-otxpc46a	168	10	in	in	IN
cord-262786-otxpc46a	168	11	FLAIR	flair	NN
cord-262786-otxpc46a	168	12	images	image	NNS
cord-262786-otxpc46a	168	13	along	along	IN
cord-262786-otxpc46a	168	14	with	with	IN
cord-262786-otxpc46a	168	15	abnormalities	abnormality	NNS
cord-262786-otxpc46a	168	16	in	in	IN
cord-262786-otxpc46a	168	17	frontal	frontal	JJ
cord-262786-otxpc46a	168	18	,	,	,
cord-262786-otxpc46a	169	1	[	[	-LRB-
cord-262786-otxpc46a	169	2	5	5	CD
cord-262786-otxpc46a	169	3	]	]	-RRB-
cord-262786-otxpc46a	169	4	neurological	neurological	JJ
cord-262786-otxpc46a	169	5	symptoms	symptom	NNS
cord-262786-otxpc46a	169	6	developed	develop	VBD
cord-262786-otxpc46a	169	7	visual	visual	JJ
cord-262786-otxpc46a	169	8	acuity	acuity	NN
cord-262786-otxpc46a	169	9	and	and	CC
cord-262786-otxpc46a	169	10	field	field	NN
cord-262786-otxpc46a	169	11	defects	defect	NNS
cord-262786-otxpc46a	169	12	and	and	CC
cord-262786-otxpc46a	169	13	hyperreflexia	hyperreflexia	NN
cord-262786-otxpc46a	169	14	.	.	.
cord-262786-otxpc46a	170	1	Orbital	orbital	JJ
cord-262786-otxpc46a	170	2	and	and	CC
cord-262786-otxpc46a	170	3	brain	brain	NN
cord-262786-otxpc46a	170	4	MRI	MRI	NNP
cord-262786-otxpc46a	170	5	investigations	investigation	NNS
cord-262786-otxpc46a	170	6	demonstrated	demonstrate	VBD
cord-262786-otxpc46a	170	7	enhancement	enhancement	NN
cord-262786-otxpc46a	170	8	of	of	IN
cord-262786-otxpc46a	170	9	left	left	JJ
cord-262786-otxpc46a	170	10	optic	optic	JJ
cord-262786-otxpc46a	170	11	nerve	nerve	NN
cord-262786-otxpc46a	170	12	accompanied	accompany	VBN
cord-262786-otxpc46a	170	13	by	by	IN
cord-262786-otxpc46a	170	14	demyelinating	demyelinate	VBG
cord-262786-otxpc46a	170	15	lesions	lesion	NNS
cord-262786-otxpc46a	170	16	in	in	IN
cord-262786-otxpc46a	170	17	supratentorial	supratentorial	NNP
cord-262786-otxpc46a	170	18	periventricular	periventricular	NNP
cord-262786-otxpc46a	170	19	areas	area	NNS
cord-262786-otxpc46a	170	20	of	of	IN
cord-262786-otxpc46a	170	21	occipital	occipital	JJ
cord-262786-otxpc46a	170	22	and	and	CC
cord-262786-otxpc46a	170	23	temporal	temporal	JJ
cord-262786-otxpc46a	170	24	lobes	lobe	NNS
cord-262786-otxpc46a	170	25	(	(	-LRB-
cord-262786-otxpc46a	170	26	Table	table	NN
cord-262786-otxpc46a	170	27	2	2	CD
cord-262786-otxpc46a	170	28	)	)	-RRB-
cord-262786-otxpc46a	170	29	.	.	.
cord-262786-otxpc46a	171	1	Interestingly	interestingly	RB
cord-262786-otxpc46a	171	2	,	,	,
cord-262786-otxpc46a	171	3	CSF	CSF	NNP
cord-262786-otxpc46a	171	4	PCR	PCR	NNP
cord-262786-otxpc46a	171	5	analysis	analysis	NN
cord-262786-otxpc46a	171	6	of	of	IN
cord-262786-otxpc46a	171	7	SARS	SARS	NNP
cord-262786-otxpc46a	171	8	-	-	HYPH
cord-262786-otxpc46a	171	9	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	171	10	was	be	VBD
cord-262786-otxpc46a	171	11	negative	negative	JJ
cord-262786-otxpc46a	171	12	,	,	,
cord-262786-otxpc46a	171	13	while	while	IN
cord-262786-otxpc46a	171	14	CSF	CSF	NNP
cord-262786-otxpc46a	171	15	oligoclonal	oligoclonal	JJ
cord-262786-otxpc46a	171	16	IgG	IgG	NNP
cord-262786-otxpc46a	171	17	and	and	CC
cord-262786-otxpc46a	171	18	IgM	IgM	NNP
cord-262786-otxpc46a	171	19	were	be	VBD
cord-262786-otxpc46a	171	20	positive	positive	JJ
cord-262786-otxpc46a	171	21	,	,	,
cord-262786-otxpc46a	171	22	conferring	confer	VBG
cord-262786-otxpc46a	171	23	a	a	DT
cord-262786-otxpc46a	171	24	postinfectious	postinfectious	JJ
cord-262786-otxpc46a	171	25	immunological	immunological	JJ
cord-262786-otxpc46a	171	26	response	response	NN
cord-262786-otxpc46a	171	27	as	as	IN
cord-262786-otxpc46a	171	28	an	an	DT
cord-262786-otxpc46a	171	29	etiology	etiology	NN
cord-262786-otxpc46a	171	30	for	for	IN
cord-262786-otxpc46a	171	31	this	this	DT
cord-262786-otxpc46a	171	32	phenomenon	phenomenon	NN
cord-262786-otxpc46a	171	33	[	[	-LRB-
cord-262786-otxpc46a	171	34	80	80	CD
cord-262786-otxpc46a	171	35	]	]	-RRB-
cord-262786-otxpc46a	171	36	.	.	.
cord-262786-otxpc46a	172	1	An	an	DT
cord-262786-otxpc46a	172	2	autoimmune	autoimmune	JJ
cord-262786-otxpc46a	172	3	inflammation	inflammation	NN
cord-262786-otxpc46a	172	4	mediated	mediate	VBN
cord-262786-otxpc46a	172	5	by	by	IN
cord-262786-otxpc46a	172	6	activated	activate	VBN
cord-262786-otxpc46a	172	7	microglia	microglia	NNS
cord-262786-otxpc46a	172	8	and	and	CC
cord-262786-otxpc46a	172	9	cytotoxic	cytotoxic	JJ
cord-262786-otxpc46a	172	10	T	t	NN
cord-262786-otxpc46a	172	11	-	-	HYPH
cord-262786-otxpc46a	172	12	cells	cell	NNS
cord-262786-otxpc46a	172	13	against	against	IN
cord-262786-otxpc46a	172	14	oligodendrocytes	oligodendrocyte	NNS
cord-262786-otxpc46a	172	15	underlies	underlie	VBZ
cord-262786-otxpc46a	172	16	the	the	DT
cord-262786-otxpc46a	172	17	myelin	myelin	JJ
cord-262786-otxpc46a	172	18	degeneration	degeneration	NN
cord-262786-otxpc46a	172	19	in	in	IN
cord-262786-otxpc46a	172	20	MS	MS	NNP
cord-262786-otxpc46a	172	21	[	[	-LRB-
cord-262786-otxpc46a	172	22	51	51	CD
cord-262786-otxpc46a	172	23	]	]	-RRB-
cord-262786-otxpc46a	172	24	.	.	.
cord-262786-otxpc46a	173	1	Elevated	elevated	JJ
cord-262786-otxpc46a	173	2	levels	level	NNS
cord-262786-otxpc46a	173	3	of	of	IN
cord-262786-otxpc46a	173	4	pro	pro	JJ
cord-262786-otxpc46a	173	5	-	-	JJ
cord-262786-otxpc46a	173	6	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	173	7	cytokines	cytokine	NNS
cord-262786-otxpc46a	173	8	(	(	-LRB-
cord-262786-otxpc46a	173	9	e.g.	e.g.	RB
cord-262786-otxpc46a	173	10	,	,	,
cord-262786-otxpc46a	173	11	TNF	TNF	NNP
cord-262786-otxpc46a	173	12	-	-	HYPH
cord-262786-otxpc46a	173	13	α	α	NNP
cord-262786-otxpc46a	173	14	,	,	,
cord-262786-otxpc46a	173	15	IL-6	IL-6	NNP
cord-262786-otxpc46a	173	16	,	,	,
cord-262786-otxpc46a	173	17	IFN	IFN	NNP
cord-262786-otxpc46a	173	18	-	-	HYPH
cord-262786-otxpc46a	173	19	γ	γ	NNP
cord-262786-otxpc46a	173	20	,	,	,
cord-262786-otxpc46a	173	21	IL-1β	IL-1β	NNP
cord-262786-otxpc46a	173	22	)	)	-RRB-
cord-262786-otxpc46a	173	23	are	be	VBP
cord-262786-otxpc46a	173	24	found	find	VBN
cord-262786-otxpc46a	173	25	in	in	IN
cord-262786-otxpc46a	173	26	the	the	DT
cord-262786-otxpc46a	173	27	CSF	CSF	NNP
cord-262786-otxpc46a	173	28	of	of	IN
cord-262786-otxpc46a	173	29	MS	MS	NNP
cord-262786-otxpc46a	173	30	patients	patient	NNS
cord-262786-otxpc46a	173	31	suffering	suffer	VBG
cord-262786-otxpc46a	173	32	from	from	IN
cord-262786-otxpc46a	173	33	either	either	DT
cord-262786-otxpc46a	173	34	white	white	JJ
cord-262786-otxpc46a	173	35	matter	matter	NN
cord-262786-otxpc46a	173	36	or	or	CC
cord-262786-otxpc46a	173	37	gray	gray	JJ
cord-262786-otxpc46a	173	38	matter	matter	NN
cord-262786-otxpc46a	173	39	deficits	deficit	NNS
cord-262786-otxpc46a	173	40	[	[	-LRB-
cord-262786-otxpc46a	173	41	24	24	CD
cord-262786-otxpc46a	173	42	]	]	-RRB-
cord-262786-otxpc46a	173	43	.	.	.
cord-262786-otxpc46a	174	1	TNF	TNF	NNP
cord-262786-otxpc46a	174	2	-	-	HYPH
cord-262786-otxpc46a	174	3	α	α	NNP
cord-262786-otxpc46a	174	4	is	be	VBZ
cord-262786-otxpc46a	174	5	isolated	isolate	VBN
cord-262786-otxpc46a	174	6	from	from	IN
cord-262786-otxpc46a	174	7	active	active	JJ
cord-262786-otxpc46a	174	8	areas	area	NNS
cord-262786-otxpc46a	174	9	of	of	IN
cord-262786-otxpc46a	174	10	neurodegeneration	neurodegeneration	NN
cord-262786-otxpc46a	174	11	in	in	IN
cord-262786-otxpc46a	174	12	postmortem	postmortem	JJ
cord-262786-otxpc46a	174	13	MS	MS	NNP
cord-262786-otxpc46a	174	14	brains	brain	NNS
cord-262786-otxpc46a	174	15	[	[	-LRB-
cord-262786-otxpc46a	174	16	57	57	CD
cord-262786-otxpc46a	174	17	]	]	-RRB-
cord-262786-otxpc46a	174	18	.	.	.
cord-262786-otxpc46a	175	1	Overexpression	Overexpression	NNP
cord-262786-otxpc46a	175	2	of	of	IN
cord-262786-otxpc46a	175	3	TNF	TNF	NNP
cord-262786-otxpc46a	175	4	-	-	HYPH
cord-262786-otxpc46a	175	5	α	α	NNP
cord-262786-otxpc46a	175	6	stimulates	stimulate	VBZ
cord-262786-otxpc46a	175	7	apoptosis	apoptosis	NN
cord-262786-otxpc46a	175	8	of	of	IN
cord-262786-otxpc46a	175	9	oligodendrocytes	oligodendrocyte	NNS
cord-262786-otxpc46a	175	10	and	and	CC
cord-262786-otxpc46a	175	11	infiltration	infiltration	NN
cord-262786-otxpc46a	175	12	of	of	IN
cord-262786-otxpc46a	175	13	immune	immune	JJ
cord-262786-otxpc46a	175	14	cells	cell	NNS
cord-262786-otxpc46a	175	15	into	into	IN
cord-262786-otxpc46a	175	16	the	the	DT
cord-262786-otxpc46a	175	17	CSF	CSF	NNP
cord-262786-otxpc46a	175	18	,	,	,
cord-262786-otxpc46a	175	19	while	while	IN
cord-262786-otxpc46a	175	20	intrathecal	intrathecal	JJ
cord-262786-otxpc46a	175	21	injection	injection	NN
cord-262786-otxpc46a	175	22	of	of	IN
cord-262786-otxpc46a	175	23	TNF	TNF	NNP
cord-262786-otxpc46a	175	24	-	-	HYPH
cord-262786-otxpc46a	175	25	α	α	NNP
cord-262786-otxpc46a	175	26	monoclonal	monoclonal	JJ
cord-262786-otxpc46a	175	27	antibodies	antibody	NNS
cord-262786-otxpc46a	175	28	prevents	prevent	VBZ
cord-262786-otxpc46a	175	29	from	from	IN
cord-262786-otxpc46a	175	30	the	the	DT
cord-262786-otxpc46a	175	31	development	development	NN
cord-262786-otxpc46a	175	32	of	of	IN
cord-262786-otxpc46a	175	33	MS	MS	NNP
cord-262786-otxpc46a	175	34	in	in	IN
cord-262786-otxpc46a	175	35	animal	animal	NN
cord-262786-otxpc46a	175	36	models	model	NNS
cord-262786-otxpc46a	175	37	of	of	IN
cord-262786-otxpc46a	175	38	experimental	experimental	JJ
cord-262786-otxpc46a	175	39	autoimmune	autoimmune	JJ
cord-262786-otxpc46a	175	40	encephalomyelitis	encephalomyelitis	NN
cord-262786-otxpc46a	175	41	(	(	-LRB-
cord-262786-otxpc46a	175	42	EAE	EAE	NNP
cord-262786-otxpc46a	175	43	)	)	-RRB-
cord-262786-otxpc46a	175	44	[	[	-LRB-
cord-262786-otxpc46a	175	45	57	57	CD
cord-262786-otxpc46a	175	46	]	]	-RRB-
cord-262786-otxpc46a	175	47	.	.	.
cord-262786-otxpc46a	176	1	IL-6	IL-6	NNP
cord-262786-otxpc46a	176	2	maintains	maintain	VBZ
cord-262786-otxpc46a	176	3	the	the	DT
cord-262786-otxpc46a	176	4	balance	balance	NN
cord-262786-otxpc46a	176	5	between	between	IN
cord-262786-otxpc46a	176	6	cytotoxic	cytotoxic	JJ
cord-262786-otxpc46a	176	7	and	and	CC
cord-262786-otxpc46a	176	8	regulatory	regulatory	JJ
cord-262786-otxpc46a	176	9	T	t	NN
cord-262786-otxpc46a	176	10	-	-	HYPH
cord-262786-otxpc46a	176	11	cells	cell	NNS
cord-262786-otxpc46a	176	12	.	.	.
cord-262786-otxpc46a	177	1	Overproduction	overproduction	NN
cord-262786-otxpc46a	177	2	of	of	IN
cord-262786-otxpc46a	177	3	IL-6	IL-6	NNP
cord-262786-otxpc46a	177	4	inhibits	inhibit	VBZ
cord-262786-otxpc46a	177	5	the	the	DT
cord-262786-otxpc46a	177	6	differentiation	differentiation	NN
cord-262786-otxpc46a	177	7	of	of	IN
cord-262786-otxpc46a	177	8	T	t	NN
cord-262786-otxpc46a	177	9	-	-	HYPH
cord-262786-otxpc46a	177	10	cells	cell	NNS
cord-262786-otxpc46a	177	11	into	into	IN
cord-262786-otxpc46a	177	12	regulatory	regulatory	JJ
cord-262786-otxpc46a	177	13	T	t	NN
cord-262786-otxpc46a	177	14	-	-	HYPH
cord-262786-otxpc46a	177	15	cells	cell	NNS
cord-262786-otxpc46a	177	16	and	and	CC
cord-262786-otxpc46a	177	17	thus	thus	RB
cord-262786-otxpc46a	177	18	promotes	promote	VBZ
cord-262786-otxpc46a	177	19	the	the	DT
cord-262786-otxpc46a	177	20	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	177	21	state	state	NN
cord-262786-otxpc46a	177	22	and	and	CC
cord-262786-otxpc46a	177	23	demyelination	demyelination	NN
cord-262786-otxpc46a	177	24	in	in	IN
cord-262786-otxpc46a	177	25	mice	mouse	NNS
cord-262786-otxpc46a	177	26	[	[	-LRB-
cord-262786-otxpc46a	177	27	57	57	CD
cord-262786-otxpc46a	177	28	]	]	-RRB-
cord-262786-otxpc46a	177	29	.	.	.
cord-262786-otxpc46a	178	1	In	in	IN
cord-262786-otxpc46a	178	2	line	line	NN
cord-262786-otxpc46a	178	3	with	with	IN
cord-262786-otxpc46a	178	4	this	this	DT
cord-262786-otxpc46a	178	5	,	,	,
cord-262786-otxpc46a	178	6	IL-6	IL-6	NNP
cord-262786-otxpc46a	178	7	deficient	deficient	JJ
cord-262786-otxpc46a	178	8	mice	mouse	NNS
cord-262786-otxpc46a	178	9	are	be	VBP
cord-262786-otxpc46a	178	10	resistant	resistant	JJ
cord-262786-otxpc46a	178	11	to	to	IN
cord-262786-otxpc46a	178	12	MS	MS	NNP
cord-262786-otxpc46a	178	13	,	,	,
cord-262786-otxpc46a	178	14	and	and	CC
cord-262786-otxpc46a	178	15	administration	administration	NN
cord-262786-otxpc46a	178	16	of	of	IN
cord-262786-otxpc46a	178	17	IL-6	IL-6	NNP
cord-262786-otxpc46a	178	18	receptor	receptor	NN
cord-262786-otxpc46a	178	19	(	(	-LRB-
cord-262786-otxpc46a	178	20	IL-6R	IL-6R	NNP
cord-262786-otxpc46a	178	21	)	)	-RRB-
cord-262786-otxpc46a	178	22	antibodies	antibody	NNS
cord-262786-otxpc46a	178	23	inhibits	inhibit	VBZ
cord-262786-otxpc46a	178	24	the	the	DT
cord-262786-otxpc46a	178	25	myelin	myelin	JJ
cord-262786-otxpc46a	178	26	degeneration	degeneration	NN
cord-262786-otxpc46a	178	27	in	in	IN
cord-262786-otxpc46a	178	28	EAE	EAE	NNP
cord-262786-otxpc46a	178	29	mice	mouse	NNS
cord-262786-otxpc46a	178	30	[	[	-LRB-
cord-262786-otxpc46a	178	31	57	57	CD
cord-262786-otxpc46a	178	32	]	]	-RRB-
cord-262786-otxpc46a	178	33	.	.	.
cord-262786-otxpc46a	179	1	Moreover	moreover	RB
cord-262786-otxpc46a	179	2	,	,	,
cord-262786-otxpc46a	179	3	the	the	DT
cord-262786-otxpc46a	179	4	aberrant	aberrant	JJ
cord-262786-otxpc46a	179	5	release	release	NN
cord-262786-otxpc46a	179	6	of	of	IN
cord-262786-otxpc46a	179	7	IL-6	IL-6	NNP
cord-262786-otxpc46a	179	8	disrupts	disrupt	VBZ
cord-262786-otxpc46a	179	9	the	the	DT
cord-262786-otxpc46a	179	10	blood	blood	NN
cord-262786-otxpc46a	179	11	-	-	HYPH
cord-262786-otxpc46a	179	12	brain	brain	NN
cord-262786-otxpc46a	179	13	barrier	barrier	NN
cord-262786-otxpc46a	179	14	integrity	integrity	NN
cord-262786-otxpc46a	179	15	and	and	CC
cord-262786-otxpc46a	179	16	facilitates	facilitate	VBZ
cord-262786-otxpc46a	179	17	the	the	DT
cord-262786-otxpc46a	179	18	infiltration	infiltration	NN
cord-262786-otxpc46a	179	19	of	of	IN
cord-262786-otxpc46a	179	20	cytotoxic	cytotoxic	JJ
cord-262786-otxpc46a	179	21	T	t	NN
cord-262786-otxpc46a	179	22	-	-	HYPH
cord-262786-otxpc46a	179	23	cells	cell	NNS
cord-262786-otxpc46a	179	24	[	[	-LRB-
cord-262786-otxpc46a	179	25	57	57	CD
cord-262786-otxpc46a	179	26	]	]	-RRB-
cord-262786-otxpc46a	179	27	.	.	.
cord-262786-otxpc46a	180	1	Last	last	JJ
cord-262786-otxpc46a	180	2	but	but	CC
cord-262786-otxpc46a	180	3	not	not	RB
cord-262786-otxpc46a	180	4	least	least	JJS
cord-262786-otxpc46a	180	5	,	,	,
cord-262786-otxpc46a	180	6	IL-1β	il-1β	NN
cord-262786-otxpc46a	180	7	receptor	receptor	NN
cord-262786-otxpc46a	181	1	(	(	-LRB-
cord-262786-otxpc46a	181	2	IL-1βR	il-1βr	NN
cord-262786-otxpc46a	181	3	)	)	-RRB-
cord-262786-otxpc46a	181	4	antibodies	antibody	NNS
cord-262786-otxpc46a	181	5	antagonize	antagonize	VBP
cord-262786-otxpc46a	181	6	the	the	DT
cord-262786-otxpc46a	181	7	demyelination	demyelination	NN
cord-262786-otxpc46a	181	8	process	process	NN
cord-262786-otxpc46a	181	9	in	in	IN
cord-262786-otxpc46a	181	10	rat	rat	NN
cord-262786-otxpc46a	181	11	models	model	NNS
cord-262786-otxpc46a	181	12	of	of	IN
cord-262786-otxpc46a	181	13	EAE	EAE	NNP
cord-262786-otxpc46a	181	14	,	,	,
cord-262786-otxpc46a	181	15	which	which	WDT
cord-262786-otxpc46a	181	16	suggests	suggest	VBZ
cord-262786-otxpc46a	181	17	a	a	DT
cord-262786-otxpc46a	181	18	role	role	NN
cord-262786-otxpc46a	181	19	for	for	IN
cord-262786-otxpc46a	181	20	IL-1β	il-1β	ADD
cord-262786-otxpc46a	181	21	in	in	IN
cord-262786-otxpc46a	181	22	the	the	DT
cord-262786-otxpc46a	181	23	pathogenesis	pathogenesis	NN
cord-262786-otxpc46a	181	24	of	of	IN
cord-262786-otxpc46a	181	25	MS	MS	NNP
cord-262786-otxpc46a	181	26	[	[	-LRB-
cord-262786-otxpc46a	181	27	81	81	CD
cord-262786-otxpc46a	181	28	]	]	-RRB-
cord-262786-otxpc46a	181	29	.	.	.
cord-262786-otxpc46a	182	1	After	after	RB
cord-262786-otxpc46a	182	2	all	all	RB
cord-262786-otxpc46a	182	3	,	,	,
cord-262786-otxpc46a	182	4	knowing	know	VBG
cord-262786-otxpc46a	182	5	that	that	IN
cord-262786-otxpc46a	182	6	the	the	DT
cord-262786-otxpc46a	182	7	aforementioned	aforementioned	JJ
cord-262786-otxpc46a	182	8	cytokines	cytokine	NNS
cord-262786-otxpc46a	182	9	surge	surge	VBP
cord-262786-otxpc46a	182	10	as	as	IN
cord-262786-otxpc46a	182	11	a	a	DT
cord-262786-otxpc46a	182	12	result	result	NN
cord-262786-otxpc46a	182	13	of	of	IN
cord-262786-otxpc46a	182	14	SARS	SARS	NNP
cord-262786-otxpc46a	182	15	-	-	HYPH
cord-262786-otxpc46a	182	16	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	182	17	mediated	mediate	VBN
cord-262786-otxpc46a	182	18	inflammation	inflammation	NN
cord-262786-otxpc46a	182	19	,	,	,
cord-262786-otxpc46a	182	20	we	-PRON-	PRP
cord-262786-otxpc46a	182	21	postulate	postulate	VBP
cord-262786-otxpc46a	182	22	that	that	IN
cord-262786-otxpc46a	182	23	persistent	persistent	JJ
cord-262786-otxpc46a	182	24	inflammation	inflammation	NN
cord-262786-otxpc46a	182	25	in	in	IN
cord-262786-otxpc46a	182	26	SARS	SARS	NNP
cord-262786-otxpc46a	182	27	-	-	HYPH
cord-262786-otxpc46a	182	28	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	182	29	may	may	MD
cord-262786-otxpc46a	182	30	propagate	propagate	VB
cord-262786-otxpc46a	182	31	myelin	myelin	JJ
cord-262786-otxpc46a	182	32	destruction	destruction	NN
cord-262786-otxpc46a	182	33	and	and	CC
cord-262786-otxpc46a	182	34	lead	lead	NN
cord-262786-otxpc46a	182	35	to	to	IN
cord-262786-otxpc46a	182	36	delayed	delay	VBN
cord-262786-otxpc46a	182	37	progression	progression	NN
cord-262786-otxpc46a	182	38	of	of	IN
cord-262786-otxpc46a	182	39	MS	MS	NNP
cord-262786-otxpc46a	182	40	.	.	.
cord-262786-otxpc46a	183	1	Moreover	moreover	RB
cord-262786-otxpc46a	183	2	,	,	,
cord-262786-otxpc46a	183	3	it	-PRON-	PRP
cord-262786-otxpc46a	183	4	is	be	VBZ
cord-262786-otxpc46a	183	5	hypothesized	hypothesize	VBN
cord-262786-otxpc46a	183	6	that	that	IN
cord-262786-otxpc46a	183	7	an	an	DT
cord-262786-otxpc46a	183	8	autoimmune	autoimmune	JJ
cord-262786-otxpc46a	183	9	reaction	reaction	NN
cord-262786-otxpc46a	183	10	mediated	mediate	VBN
cord-262786-otxpc46a	183	11	by	by	IN
cord-262786-otxpc46a	183	12	the	the	DT
cord-262786-otxpc46a	183	13	cross	cross	NN
cord-262786-otxpc46a	183	14	-	-	NN
cord-262786-otxpc46a	183	15	reaction	reaction	NN
cord-262786-otxpc46a	183	16	between	between	IN
cord-262786-otxpc46a	183	17	viral	viral	JJ
cord-262786-otxpc46a	183	18	particles	particle	NNS
cord-262786-otxpc46a	183	19	and	and	CC
cord-262786-otxpc46a	183	20	myelin	myelin	JJ
cord-262786-otxpc46a	183	21	basic	basic	JJ
cord-262786-otxpc46a	183	22	protein	protein	NN
cord-262786-otxpc46a	183	23	may	may	MD
cord-262786-otxpc46a	183	24	provide	provide	VB
cord-262786-otxpc46a	183	25	the	the	DT
cord-262786-otxpc46a	183	26	driving	drive	VBG
cord-262786-otxpc46a	183	27	force	force	NN
cord-262786-otxpc46a	183	28	for	for	IN
cord-262786-otxpc46a	183	29	neural	neural	JJ
cord-262786-otxpc46a	183	30	demyelination	demyelination	NN
cord-262786-otxpc46a	183	31	.	.	.
cord-262786-otxpc46a	184	1	This	this	DT
cord-262786-otxpc46a	184	2	hypothesis	hypothesis	NN
cord-262786-otxpc46a	184	3	is	be	VBZ
cord-262786-otxpc46a	184	4	supported	support	VBN
cord-262786-otxpc46a	184	5	by	by	IN
cord-262786-otxpc46a	184	6	the	the	DT
cord-262786-otxpc46a	184	7	fact	fact	NN
cord-262786-otxpc46a	184	8	that	that	IN
cord-262786-otxpc46a	184	9	genome	genome	NN
cord-262786-otxpc46a	184	10	of	of	IN
cord-262786-otxpc46a	184	11	other	other	JJ
cord-262786-otxpc46a	184	12	coronaviruses	coronaviruse	NNS
cord-262786-otxpc46a	184	13	like	like	IN
cord-262786-otxpc46a	184	14	CoV	CoV	NNP
cord-262786-otxpc46a	184	15	-	-	:
cord-262786-otxpc46a	184	16	OC43	OC43	NNP
cord-262786-otxpc46a	184	17	and	and	CC
cord-262786-otxpc46a	184	18	CoV-229E	CoV-229E	NNP
cord-262786-otxpc46a	184	19	,	,	,
cord-262786-otxpc46a	184	20	as	as	RB
cord-262786-otxpc46a	184	21	well	well	RB
cord-262786-otxpc46a	184	22	as	as	IN
cord-262786-otxpc46a	184	23	their	-PRON-	PRP$
cord-262786-otxpc46a	184	24	antibodies	antibody	NNS
cord-262786-otxpc46a	184	25	,	,	,
cord-262786-otxpc46a	184	26	are	be	VBP
cord-262786-otxpc46a	184	27	isolated	isolate	VBN
cord-262786-otxpc46a	184	28	from	from	IN
cord-262786-otxpc46a	184	29	CNS	CNS	NNP
cord-262786-otxpc46a	184	30	of	of	IN
cord-262786-otxpc46a	184	31	MS	MS	NNP
cord-262786-otxpc46a	184	32	patients	patient	NNS
cord-262786-otxpc46a	184	33	,	,	,
cord-262786-otxpc46a	184	34	and	and	CC
cord-262786-otxpc46a	184	35	coronavirus	coronavirus	NN
cord-262786-otxpc46a	184	36	-	-	HYPH
cord-262786-otxpc46a	184	37	like	like	JJ
cord-262786-otxpc46a	184	38	particles	particle	NNS
cord-262786-otxpc46a	184	39	are	be	VBP
cord-262786-otxpc46a	184	40	found	find	VBN
cord-262786-otxpc46a	184	41	in	in	IN
cord-262786-otxpc46a	184	42	perivascular	perivascular	JJ
cord-262786-otxpc46a	184	43	cuffs	cuff	NNS
cord-262786-otxpc46a	184	44	of	of	IN
cord-262786-otxpc46a	184	45	human	human	JJ
cord-262786-otxpc46a	184	46	MS	MS	NNP
cord-262786-otxpc46a	184	47	brain	brain	NN
cord-262786-otxpc46a	184	48	[	[	-LRB-
cord-262786-otxpc46a	184	49	82	82	CD
cord-262786-otxpc46a	184	50	]	]	-RRB-
cord-262786-otxpc46a	184	51	.	.	.
cord-262786-otxpc46a	185	1	In	in	IN
cord-262786-otxpc46a	185	2	fact	fact	NN
cord-262786-otxpc46a	185	3	,	,	,
cord-262786-otxpc46a	185	4	the	the	DT
cord-262786-otxpc46a	185	5	virus	virus	NN
cord-262786-otxpc46a	185	6	might	may	MD
cord-262786-otxpc46a	185	7	lie	lie	VB
cord-262786-otxpc46a	185	8	dormant	dormant	JJ
cord-262786-otxpc46a	185	9	in	in	IN
cord-262786-otxpc46a	185	10	astrocytes	astrocyte	NNS
cord-262786-otxpc46a	185	11	and	and	CC
cord-262786-otxpc46a	185	12	oligodendrocytes	oligodendrocyte	NNS
cord-262786-otxpc46a	185	13	and	and	CC
cord-262786-otxpc46a	185	14	trigger	trigger	VB
cord-262786-otxpc46a	185	15	the	the	DT
cord-262786-otxpc46a	185	16	autoimmunity	autoimmunity	NN
cord-262786-otxpc46a	185	17	mediated	mediate	VBN
cord-262786-otxpc46a	185	18	by	by	IN
cord-262786-otxpc46a	185	19	molecular	molecular	JJ
cord-262786-otxpc46a	185	20	mimicry	mimicry	NN
cord-262786-otxpc46a	185	21	.	.	.
cord-262786-otxpc46a	186	1	Interestingly	interestingly	RB
cord-262786-otxpc46a	186	2	,	,	,
cord-262786-otxpc46a	186	3	intracranial	intracranial	JJ
cord-262786-otxpc46a	186	4	inoculation	inoculation	NN
cord-262786-otxpc46a	186	5	of	of	IN
cord-262786-otxpc46a	186	6	murine	murine	JJ
cord-262786-otxpc46a	186	7	coronavirus	coronavirus	NN
cord-262786-otxpc46a	186	8	(	(	-LRB-
cord-262786-otxpc46a	186	9	mouse	mouse	NN
cord-262786-otxpc46a	186	10	hepatic	hepatic	JJ
cord-262786-otxpc46a	186	11	virus	virus	NN
cord-262786-otxpc46a	186	12	(	(	-LRB-
cord-262786-otxpc46a	186	13	MHV	MHV	NNP
cord-262786-otxpc46a	186	14	)	)	-RRB-
cord-262786-otxpc46a	186	15	)	)	-RRB-
cord-262786-otxpc46a	186	16	,	,	,
cord-262786-otxpc46a	186	17	induces	induce	VBZ
cord-262786-otxpc46a	186	18	optic	optic	JJ
cord-262786-otxpc46a	186	19	neuritis	neuritis	NN
cord-262786-otxpc46a	186	20	and	and	CC
cord-262786-otxpc46a	186	21	focal	focal	JJ
cord-262786-otxpc46a	186	22	encephalitis	encephalitis	RB
cord-262786-otxpc46a	186	23	leading	lead	VBG
cord-262786-otxpc46a	186	24	to	to	IN
cord-262786-otxpc46a	186	25	chronic	chronic	JJ
cord-262786-otxpc46a	186	26	demyelination	demyelination	NN
cord-262786-otxpc46a	186	27	in	in	IN
cord-262786-otxpc46a	186	28	mice	mouse	NNS
cord-262786-otxpc46a	186	29	[	[	-LRB-
cord-262786-otxpc46a	186	30	83	83	CD
cord-262786-otxpc46a	186	31	]	]	-RRB-
cord-262786-otxpc46a	186	32	.	.	.
cord-262786-otxpc46a	187	1	In	in	IN
cord-262786-otxpc46a	187	2	this	this	DT
cord-262786-otxpc46a	187	3	case	case	NN
cord-262786-otxpc46a	187	4	,	,	,
cord-262786-otxpc46a	187	5	both	both	DT
cord-262786-otxpc46a	187	6	innate	innate	JJ
cord-262786-otxpc46a	187	7	and	and	CC
cord-262786-otxpc46a	187	8	adaptive	adaptive	JJ
cord-262786-otxpc46a	187	9	immune	immune	JJ
cord-262786-otxpc46a	187	10	responses	response	NNS
cord-262786-otxpc46a	187	11	comprising	comprise	VBG
cord-262786-otxpc46a	187	12	of	of	IN
cord-262786-otxpc46a	187	13	activation	activation	NN
cord-262786-otxpc46a	187	14	of	of	IN
cord-262786-otxpc46a	187	15	microglia	microglia	NN
cord-262786-otxpc46a	187	16	,	,	,
cord-262786-otxpc46a	187	17	B	b	NN
cord-262786-otxpc46a	187	18	cells	cell	NNS
cord-262786-otxpc46a	187	19	,	,	,
cord-262786-otxpc46a	187	20	CD4	CD4	NNP
cord-262786-otxpc46a	187	21	T	T	NNP
cord-262786-otxpc46a	187	22	cells	cell	NNS
cord-262786-otxpc46a	187	23	,	,	,
cord-262786-otxpc46a	187	24	and	and	CC
cord-262786-otxpc46a	187	25	[	[	-LRB-
cord-262786-otxpc46a	187	26	74	74	CD
cord-262786-otxpc46a	187	27	]	]	-RRB-
cord-262786-otxpc46a	187	28	CD8	CD8	NNP
cord-262786-otxpc46a	187	29	T	T	NNP
cord-262786-otxpc46a	187	30	cells	cell	NNS
cord-262786-otxpc46a	187	31	along	along	IN
cord-262786-otxpc46a	187	32	with	with	IN
cord-262786-otxpc46a	187	33	the	the	DT
cord-262786-otxpc46a	187	34	direct	direct	JJ
cord-262786-otxpc46a	187	35	viral	viral	JJ
cord-262786-otxpc46a	187	36	toxicity	toxicity	NN
cord-262786-otxpc46a	187	37	are	be	VBP
cord-262786-otxpc46a	187	38	proposed	propose	VBN
cord-262786-otxpc46a	187	39	to	to	TO
cord-262786-otxpc46a	187	40	mediate	mediate	VB
cord-262786-otxpc46a	187	41	myelin	myelin	NN
cord-262786-otxpc46a	187	42	stripping	strip	VBG
cord-262786-otxpc46a	187	43	[	[	-LRB-
cord-262786-otxpc46a	187	44	68	68	CD
cord-262786-otxpc46a	187	45	,	,	,
cord-262786-otxpc46a	187	46	70	70	CD
cord-262786-otxpc46a	187	47	]	]	-RRB-
cord-262786-otxpc46a	187	48	.	.	.
cord-262786-otxpc46a	188	1	GBS	GBS	NNP
cord-262786-otxpc46a	189	1	i	i	PRP
cord-262786-otxpc46a	189	2	s	s	VBZ
cord-262786-otxpc46a	189	3	a	a	DT
cord-262786-otxpc46a	189	4	pos	pos	NNP
cord-262786-otxpc46a	189	5	t	t	NN
cord-262786-otxpc46a	189	6	-	-	HYPH
cord-262786-otxpc46a	189	7	in	in	RP
cord-262786-otxpc46a	189	8	fectiou	fectiou	NNP
cord-262786-otxpc46a	189	9	s	s	POS
cord-262786-otxpc46a	189	10	autoimmune	autoimmune	NNP
cord-262786-otxpc46a	189	11	caus	caus	NNP
cord-262786-otxpc46a	189	12	e	e	NNP
cord-262786-otxpc46a	189	13	of	of	IN
cord-262786-otxpc46a	189	14	polyneuropathy	polyneuropathy	NNS
cord-262786-otxpc46a	189	15	in	in	IN
cord-262786-otxpc46a	189	16	predisposed	predisposed	JJ
cord-262786-otxpc46a	189	17	individuals	individual	NNS
cord-262786-otxpc46a	189	18	that	that	WDT
cord-262786-otxpc46a	189	19	leads	lead	VBZ
cord-262786-otxpc46a	189	20	to	to	IN
cord-262786-otxpc46a	189	21	flaccid	flaccid	JJ
cord-262786-otxpc46a	189	22	paralysis	paralysis	NN
cord-262786-otxpc46a	189	23	of	of	IN
cord-262786-otxpc46a	189	24	lower	low	JJR
cord-262786-otxpc46a	189	25	extremities	extremity	NNS
cord-262786-otxpc46a	189	26	,	,	,
cord-262786-otxpc46a	189	27	along	along	IN
cord-262786-otxpc46a	189	28	with	with	IN
cord-262786-otxpc46a	189	29	autonomic	autonomic	JJ
cord-262786-otxpc46a	189	30	and	and	CC
cord-262786-otxpc46a	189	31	sensory	sensory	JJ
cord-262786-otxpc46a	189	32	deficits	deficit	NNS
cord-262786-otxpc46a	189	33	[	[	-LRB-
cord-262786-otxpc46a	189	34	69	69	CD
cord-262786-otxpc46a	189	35	]	]	-RRB-
cord-262786-otxpc46a	189	36	.	.	.
cord-262786-otxpc46a	190	1	Autoimmunity	Autoimmunity	NNP
cord-262786-otxpc46a	190	2	is	be	VBZ
cord-262786-otxpc46a	190	3	the	the	DT
cord-262786-otxpc46a	190	4	milestone	milestone	NN
cord-262786-otxpc46a	190	5	of	of	IN
cord-262786-otxpc46a	190	6	GBS	GBS	NNP
cord-262786-otxpc46a	190	7	pathophysiology	pathophysiology	NN
cord-262786-otxpc46a	190	8	.	.	.
cord-262786-otxpc46a	191	1	Neurotrophic	Neurotrophic	NNP
cord-262786-otxpc46a	191	2	macrophages	macrophage	NNS
cord-262786-otxpc46a	191	3	present	present	JJ
cord-262786-otxpc46a	191	4	bacterial	bacterial	JJ
cord-262786-otxpc46a	191	5	or	or	CC
cord-262786-otxpc46a	191	6	viral	viral	JJ
cord-262786-otxpc46a	191	7	particles	particle	NNS
cord-262786-otxpc46a	191	8	to	to	IN
cord-262786-otxpc46a	191	9	lymphocytes	lymphocyte	NNS
cord-262786-otxpc46a	191	10	in	in	IN
cord-262786-otxpc46a	191	11	peripheral	peripheral	JJ
cord-262786-otxpc46a	191	12	nervous	nervous	JJ
cord-262786-otxpc46a	191	13	system	system	NN
cord-262786-otxpc46a	191	14	(	(	-LRB-
cord-262786-otxpc46a	191	15	PNS	PNS	NNP
cord-262786-otxpc46a	191	16	)	)	-RRB-
cord-262786-otxpc46a	191	17	[	[	-LRB-
cord-262786-otxpc46a	191	18	69	69	CD
cord-262786-otxpc46a	191	19	]	]	-RRB-
cord-262786-otxpc46a	191	20	.	.	.
cord-262786-otxpc46a	192	1	The	the	DT
cord-262786-otxpc46a	192	2	resultant	resultant	JJ
cord-262786-otxpc46a	192	3	immune	immune	JJ
cord-262786-otxpc46a	192	4	response	response	NN
cord-262786-otxpc46a	192	5	(	(	-LRB-
cord-262786-otxpc46a	192	6	i.e.	i.e.	FW
cord-262786-otxpc46a	192	7	,	,	,
cord-262786-otxpc46a	192	8	complement	complement	NN
cord-262786-otxpc46a	192	9	and	and	CC
cord-262786-otxpc46a	192	10	macrophage	macrophage	NN
cord-262786-otxpc46a	192	11	activation	activation	NN
cord-262786-otxpc46a	192	12	,	,	,
cord-262786-otxpc46a	192	13	cytokine	cytokine	NN
cord-262786-otxpc46a	192	14	release	release	NN
cord-262786-otxpc46a	192	15	,	,	,
cord-262786-otxpc46a	192	16	and	and	CC
cord-262786-otxpc46a	192	17	free	free	JJ
cord-262786-otxpc46a	192	18	radical	radical	JJ
cord-262786-otxpc46a	192	19	production	production	NN
cord-262786-otxpc46a	192	20	)	)	-RRB-
cord-262786-otxpc46a	192	21	accompanied	accompany	VBN
cord-262786-otxpc46a	192	22	with	with	IN
cord-262786-otxpc46a	192	23	the	the	DT
cord-262786-otxpc46a	192	24	molecular	molecular	JJ
cord-262786-otxpc46a	192	25	mimicry	mimicry	NN
cord-262786-otxpc46a	192	26	between	between	IN
cord-262786-otxpc46a	192	27	pathogen	pathogen	NN
cord-262786-otxpc46a	192	28	epitopes	epitope	NNS
cord-262786-otxpc46a	192	29	and	and	CC
cord-262786-otxpc46a	192	30	host	host	NN
cord-262786-otxpc46a	192	31	gangliosides	ganglioside	NNS
cord-262786-otxpc46a	192	32	such	such	JJ
cord-262786-otxpc46a	192	33	as	as	IN
cord-262786-otxpc46a	192	34	N	n	CD
cord-262786-otxpc46a	192	35	-	-	HYPH
cord-262786-otxpc46a	192	36	acetylgalactosaminyl	acetylgalactosaminyl	JJ
cord-262786-otxpc46a	192	37	GD1a	GD1a	NNP
cord-262786-otxpc46a	192	38	(	(	-LRB-
cord-262786-otxpc46a	192	39	GalNAc	galnac	NN
cord-262786-otxpc46a	192	40	-	-	HYPH
cord-262786-otxpc46a	192	41	GD1a	GD1a	NNP
cord-262786-otxpc46a	192	42	)	)	-RRB-
cord-262786-otxpc46a	192	43	,	,	,
cord-262786-otxpc46a	192	44	ganglioside	ganglioside	NN
cord-262786-otxpc46a	192	45	D1a	D1a	NNP
cord-262786-otxpc46a	192	46	(	(	-LRB-
cord-262786-otxpc46a	192	47	GD1a	GD1a	NNP
cord-262786-otxpc46a	192	48	)	)	-RRB-
cord-262786-otxpc46a	192	49	,	,	,
cord-262786-otxpc46a	192	50	ganglioside	ganglioside	NNP
cord-262786-otxpc46a	192	51	(	(	-LRB-
cord-262786-otxpc46a	192	52	GM1	GM1	NNP
cord-262786-otxpc46a	192	53	)	)	-RRB-
cord-262786-otxpc46a	192	54	,	,	,
cord-262786-otxpc46a	192	55	and	and	CC
cord-262786-otxpc46a	192	56	ganglioside	ganglioside	NN
cord-262786-otxpc46a	192	57	M1b	m1b	NN
cord-262786-otxpc46a	192	58	(	(	-LRB-
cord-262786-otxpc46a	192	59	GM1b	GM1b	NNP
cord-262786-otxpc46a	192	60	)	)	-RRB-
cord-262786-otxpc46a	192	61	and	and	CC
cord-262786-otxpc46a	192	62	myelin	myelin	NN
cord-262786-otxpc46a	192	63	proteins	protein	NNS
cord-262786-otxpc46a	192	64	result	result	VBP
cord-262786-otxpc46a	192	65	in	in	IN
cord-262786-otxpc46a	192	66	acute	acute	JJ
cord-262786-otxpc46a	192	67	neural	neural	JJ
cord-262786-otxpc46a	192	68	damage	damage	NN
cord-262786-otxpc46a	192	69	[	[	-LRB-
cord-262786-otxpc46a	192	70	69	69	CD
cord-262786-otxpc46a	192	71	]	]	-RRB-
cord-262786-otxpc46a	192	72	.	.	.
cord-262786-otxpc46a	193	1	GBS	GBS	NNP
cord-262786-otxpc46a	193	2	is	be	VBZ
cord-262786-otxpc46a	193	3	reported	report	VBN
cord-262786-otxpc46a	193	4	in	in	IN
cord-262786-otxpc46a	193	5	other	other	JJ
cord-262786-otxpc46a	193	6	post	post	JJ
cord-262786-otxpc46a	193	7	-	-	JJ
cord-262786-otxpc46a	193	8	viral	viral	JJ
cord-262786-otxpc46a	193	9	infections	infection	NNS
cord-262786-otxpc46a	193	10	,	,	,
cord-262786-otxpc46a	193	11	including	include	VBG
cord-262786-otxpc46a	193	12	influenza	influenza	NN
cord-262786-otxpc46a	193	13	,	,	,
cord-262786-otxpc46a	193	14	enteroviruses	enteroviruses	NNP
cord-262786-otxpc46a	193	15	,	,	,
cord-262786-otxpc46a	193	16	Zika	Zika	NNP
cord-262786-otxpc46a	193	17	,	,	,
cord-262786-otxpc46a	193	18	SARS	SARS	NNP
cord-262786-otxpc46a	193	19	-	-	HYPH
cord-262786-otxpc46a	193	20	CoV	CoV	NNP
cord-262786-otxpc46a	193	21	,	,	,
cord-262786-otxpc46a	193	22	MERS	MERS	NNP
cord-262786-otxpc46a	193	23	-	-	HYPH
cord-262786-otxpc46a	193	24	CoV	CoV	NNP
cord-262786-otxpc46a	193	25	,	,	,
cord-262786-otxpc46a	193	26	and	and	CC
cord-262786-otxpc46a	193	27	SARS	SARS	NNP
cord-262786-otxpc46a	193	28	-	-	HYPH
cord-262786-otxpc46a	193	29	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	193	30	[	[	-LRB-
cord-262786-otxpc46a	193	31	13	13	CD
cord-262786-otxpc46a	193	32	]	]	-RRB-
cord-262786-otxpc46a	193	33	.	.	.
cord-262786-otxpc46a	194	1	Several	several	JJ
cord-262786-otxpc46a	194	2	cases	case	NNS
cord-262786-otxpc46a	194	3	of	of	IN
cord-262786-otxpc46a	194	4	GBS	GBS	NNP
cord-262786-otxpc46a	194	5	due	due	IN
cord-262786-otxpc46a	194	6	to	to	IN
cord-262786-otxpc46a	194	7	SARS	SARS	NNP
cord-262786-otxpc46a	194	8	-	-	HYPH
cord-262786-otxpc46a	194	9	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	194	10	infection	infection	NN
cord-262786-otxpc46a	194	11	are	be	VBP
cord-262786-otxpc46a	194	12	presented	present	VBN
cord-262786-otxpc46a	194	13	in	in	IN
cord-262786-otxpc46a	194	14	the	the	DT
cord-262786-otxpc46a	194	15	literature	literature	NN
cord-262786-otxpc46a	194	16	with	with	IN
cord-262786-otxpc46a	194	17	the	the	DT
cord-262786-otxpc46a	194	18	varying	vary	VBG
cord-262786-otxpc46a	194	19	onset	onset	NN
cord-262786-otxpc46a	194	20	of	of	IN
cord-262786-otxpc46a	194	21	GBS	GBS	NNP
cord-262786-otxpc46a	194	22	symptoms	symptom	NNS
cord-262786-otxpc46a	194	23	from	from	IN
cord-262786-otxpc46a	194	24	a	a	DT
cord-262786-otxpc46a	194	25	day	day	NN
cord-262786-otxpc46a	194	26	before	before	RB
cord-262786-otxpc46a	194	27	to	to	IN
cord-262786-otxpc46a	194	28	3	3	CD
cord-262786-otxpc46a	194	29	weeks	week	NNS
cord-262786-otxpc46a	194	30	after	after	IN
cord-262786-otxpc46a	194	31	presentation	presentation	NN
cord-262786-otxpc46a	194	32	of	of	IN
cord-262786-otxpc46a	194	33	SARS	SARS	NNP
cord-262786-otxpc46a	194	34	-	-	HYPH
cord-262786-otxpc46a	194	35	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	194	36	symptoms	symptom	NNS
cord-262786-otxpc46a	194	37	[	[	-LRB-
cord-262786-otxpc46a	194	38	71	71	CD
cord-262786-otxpc46a	194	39	,	,	,
cord-262786-otxpc46a	194	40	84	84	CD
cord-262786-otxpc46a	194	41	]	]	-RRB-
cord-262786-otxpc46a	194	42	.	.	.
cord-262786-otxpc46a	195	1	Enhancement	enhancement	NN
cord-262786-otxpc46a	195	2	of	of	IN
cord-262786-otxpc46a	195	3	cervical	cervical	JJ
cord-262786-otxpc46a	195	4	and	and	CC
cord-262786-otxpc46a	195	5	cranial	cranial	JJ
cord-262786-otxpc46a	195	6	roots	root	NNS
cord-262786-otxpc46a	195	7	(	(	-LRB-
cord-262786-otxpc46a	195	8	e.g.	e.g.	RB
cord-262786-otxpc46a	195	9	,	,	,
cord-262786-otxpc46a	195	10	optic	optic	NN
cord-262786-otxpc46a	195	11	,	,	,
cord-262786-otxpc46a	195	12	oculomotor	oculomotor	NN
cord-262786-otxpc46a	195	13	,	,	,
cord-262786-otxpc46a	195	14	and	and	CC
cord-262786-otxpc46a	195	15	facial	facial	JJ
cord-262786-otxpc46a	195	16	nerves	nerve	NNS
cord-262786-otxpc46a	195	17	)	)	-RRB-
cord-262786-otxpc46a	195	18	in	in	IN
cord-262786-otxpc46a	195	19	MRI	MRI	NNP
cord-262786-otxpc46a	195	20	studies	study	NNS
cord-262786-otxpc46a	195	21	along	along	IN
cord-262786-otxpc46a	195	22	with	with	IN
cord-262786-otxpc46a	195	23	presence	presence	NN
cord-262786-otxpc46a	195	24	of	of	IN
cord-262786-otxpc46a	195	25	axonal	axonal	JJ
cord-262786-otxpc46a	195	26	and	and	CC
cord-262786-otxpc46a	195	27	demyelinating	demyelinating	JJ
cord-262786-otxpc46a	195	28	patterns	pattern	NNS
cord-262786-otxpc46a	195	29	in	in	IN
cord-262786-otxpc46a	195	30	nerve	nerve	NN
cord-262786-otxpc46a	195	31	conduction	conduction	NN
cord-262786-otxpc46a	195	32	studies	study	NNS
cord-262786-otxpc46a	195	33	are	be	VBP
cord-262786-otxpc46a	195	34	suggestive	suggestive	JJ
cord-262786-otxpc46a	195	35	of	of	IN
cord-262786-otxpc46a	195	36	GBS	GBS	NNP
cord-262786-otxpc46a	195	37	in	in	IN
cord-262786-otxpc46a	195	38	SARS	SARS	NNP
cord-262786-otxpc46a	195	39	-	-	HYPH
cord-262786-otxpc46a	195	40	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	195	41	patients	patient	NNS
cord-262786-otxpc46a	195	42	(	(	-LRB-
cord-262786-otxpc46a	195	43	Table	table	NN
cord-262786-otxpc46a	195	44	2	2	CD
cord-262786-otxpc46a	195	45	)	)	-RRB-
cord-262786-otxpc46a	195	46	[	[	-LRB-
cord-262786-otxpc46a	195	47	71	71	CD
cord-262786-otxpc46a	195	48	,	,	,
cord-262786-otxpc46a	195	49	[	[	-LRB-
cord-262786-otxpc46a	195	50	84	84	CD
cord-262786-otxpc46a	195	51	]	]	-RRB-
cord-262786-otxpc46a	195	52	[	[	-LRB-
cord-262786-otxpc46a	195	53	85	85	CD
cord-262786-otxpc46a	195	54	]	]	-RRB-
cord-262786-otxpc46a	195	55	[	[	-LRB-
cord-262786-otxpc46a	195	56	86	86	CD
cord-262786-otxpc46a	195	57	]	]	-RRB-
cord-262786-otxpc46a	195	58	.	.	.
cord-262786-otxpc46a	196	1	Several	several	JJ
cord-262786-otxpc46a	196	2	findings	finding	NNS
cord-262786-otxpc46a	196	3	indicate	indicate	VBP
cord-262786-otxpc46a	196	4	that	that	IN
cord-262786-otxpc46a	196	5	the	the	DT
cord-262786-otxpc46a	196	6	occurrence	occurrence	NN
cord-262786-otxpc46a	196	7	of	of	IN
cord-262786-otxpc46a	196	8	GBS	GBS	NNP
cord-262786-otxpc46a	196	9	in	in	IN
cord-262786-otxpc46a	196	10	SARS	SARS	NNP
cord-262786-otxpc46a	196	11	-	-	HYPH
cord-262786-otxpc46a	196	12	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	196	13	is	be	VBZ
cord-262786-otxpc46a	196	14	mediated	mediate	VBN
cord-262786-otxpc46a	196	15	by	by	IN
cord-262786-otxpc46a	196	16	an	an	DT
cord-262786-otxpc46a	196	17	autoimmune	autoimmune	JJ
cord-262786-otxpc46a	196	18	response	response	NN
cord-262786-otxpc46a	196	19	mediated	mediate	VBN
cord-262786-otxpc46a	196	20	by	by	IN
cord-262786-otxpc46a	196	21	molecular	molecular	JJ
cord-262786-otxpc46a	196	22	mimicry	mimicry	NN
cord-262786-otxpc46a	196	23	and	and	CC
cord-262786-otxpc46a	196	24	not	not	RB
cord-262786-otxpc46a	196	25	the	the	DT
cord-262786-otxpc46a	196	26	direct	direct	JJ
cord-262786-otxpc46a	196	27	viral	viral	JJ
cord-262786-otxpc46a	196	28	invasion	invasion	NN
cord-262786-otxpc46a	196	29	.	.	.
cord-262786-otxpc46a	197	1	Binding	bind	VBG
cord-262786-otxpc46a	197	2	of	of	IN
cord-262786-otxpc46a	197	3	SARS	SARS	NNP
cord-262786-otxpc46a	197	4	-	-	HYPH
cord-262786-otxpc46a	197	5	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	197	6	spike	spike	NN
cord-262786-otxpc46a	197	7	protein	protein	NN
cord-262786-otxpc46a	197	8	to	to	IN
cord-262786-otxpc46a	197	9	cell	cell	NN
cord-262786-otxpc46a	197	10	surface	surface	NN
cord-262786-otxpc46a	197	11	occurs	occur	VBZ
cord-262786-otxpc46a	197	12	not	not	RB
cord-262786-otxpc46a	197	13	only	only	RB
cord-262786-otxpc46a	197	14	through	through	IN
cord-262786-otxpc46a	197	15	ACE-2	ACE-2	NNP
cord-262786-otxpc46a	197	16	receptors	receptor	NNS
cord-262786-otxpc46a	197	17	but	but	CC
cord-262786-otxpc46a	197	18	also	also	RB
cord-262786-otxpc46a	197	19	through	through	IN
cord-262786-otxpc46a	197	20	sialic	sialic	JJ
cord-262786-otxpc46a	197	21	acid	acid	NN
cord-262786-otxpc46a	197	22	-	-	HYPH
cord-262786-otxpc46a	197	23	containing	contain	VBG
cord-262786-otxpc46a	197	24	glycoproteins	glycoprotein	NNS
cord-262786-otxpc46a	197	25	and	and	CC
cord-262786-otxpc46a	197	26	gangliosides	ganglioside	NNS
cord-262786-otxpc46a	197	27	.	.	.
cord-262786-otxpc46a	198	1	Considering	consider	VBG
cord-262786-otxpc46a	198	2	the	the	DT
cord-262786-otxpc46a	198	3	fact	fact	NN
cord-262786-otxpc46a	198	4	that	that	IN
cord-262786-otxpc46a	198	5	anti	anti	JJ
cord-262786-otxpc46a	198	6	-	-	JJ
cord-262786-otxpc46a	198	7	ganglioside	ganglioside	JJ
cord-262786-otxpc46a	198	8	antibodies	antibody	NNS
cord-262786-otxpc46a	198	9	are	be	VBP
cord-262786-otxpc46a	198	10	found	find	VBN
cord-262786-otxpc46a	198	11	in	in	IN
cord-262786-otxpc46a	198	12	the	the	DT
cord-262786-otxpc46a	198	13	serum	serum	NN
cord-262786-otxpc46a	198	14	of	of	IN
cord-262786-otxpc46a	198	15	SARS	SARS	NNP
cord-262786-otxpc46a	198	16	-	-	HYPH
cord-262786-otxpc46a	198	17	CoV-2-triggered	cov-2-triggere	VBN
cord-262786-otxpc46a	198	18	GBS	GBS	NNP
cord-262786-otxpc46a	198	19	patients	patient	NNS
cord-262786-otxpc46a	198	20	,	,	,
cord-262786-otxpc46a	198	21	a	a	DT
cord-262786-otxpc46a	198	22	cross	cross	NN
cord-262786-otxpc46a	198	23	-	-	NN
cord-262786-otxpc46a	198	24	reactivity	reactivity	NN
cord-262786-otxpc46a	198	25	between	between	IN
cord-262786-otxpc46a	198	26	SARS	SARS	NNP
cord-262786-otxpc46a	198	27	-	-	HYPH
cord-262786-otxpc46a	198	28	CoV-2-binding	cov-2-binde	VBG
cord-262786-otxpc46a	198	29	gangliosides	ganglioside	NNS
cord-262786-otxpc46a	198	30	and	and	CC
cord-262786-otxpc46a	198	31	peripheral	peripheral	JJ
cord-262786-otxpc46a	198	32	nerve	nerve	NN
cord-262786-otxpc46a	198	33	glycolipids	glycolipid	NNS
cord-262786-otxpc46a	198	34	are	be	VBP
cord-262786-otxpc46a	198	35	implicated	implicate	VBN
cord-262786-otxpc46a	198	36	[	[	-LRB-
cord-262786-otxpc46a	198	37	87	87	CD
cord-262786-otxpc46a	198	38	]	]	-RRB-
cord-262786-otxpc46a	198	39	.	.	.
cord-262786-otxpc46a	199	1	Also	also	RB
cord-262786-otxpc46a	199	2	,	,	,
cord-262786-otxpc46a	199	3	recent	recent	JJ
cord-262786-otxpc46a	199	4	experiments	experiment	NNS
cord-262786-otxpc46a	199	5	are	be	VBP
cord-262786-otxpc46a	199	6	not	not	RB
cord-262786-otxpc46a	199	7	able	able	JJ
cord-262786-otxpc46a	199	8	to	to	TO
cord-262786-otxpc46a	199	9	detect	detect	VB
cord-262786-otxpc46a	199	10	the	the	DT
cord-262786-otxpc46a	199	11	viral	viral	JJ
cord-262786-otxpc46a	199	12	genome	genome	NN
cord-262786-otxpc46a	199	13	in	in	IN
cord-262786-otxpc46a	199	14	CSF	CSF	NNP
cord-262786-otxpc46a	199	15	of	of	IN
cord-262786-otxpc46a	199	16	a	a	DT
cord-262786-otxpc46a	199	17	high	high	JJ
cord-262786-otxpc46a	199	18	proportion	proportion	NN
cord-262786-otxpc46a	199	19	of	of	IN
cord-262786-otxpc46a	199	20	post	post	JJ
cord-262786-otxpc46a	199	21	-	-	JJ
cord-262786-otxpc46a	199	22	SARS	SARS	NNP
cord-262786-otxpc46a	199	23	-	-	HYPH
cord-262786-otxpc46a	199	24	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	199	25	GBS	GBS	NNP
cord-262786-otxpc46a	199	26	patients	patient	NNS
cord-262786-otxpc46a	199	27	[	[	-LRB-
cord-262786-otxpc46a	199	28	23	23	CD
cord-262786-otxpc46a	199	29	,	,	,
cord-262786-otxpc46a	199	30	39	39	CD
cord-262786-otxpc46a	199	31	,	,	,
cord-262786-otxpc46a	199	32	72	72	CD
cord-262786-otxpc46a	199	33	]	]	-RRB-
cord-262786-otxpc46a	199	34	.	.	.
cord-262786-otxpc46a	200	1	Moreover	moreover	RB
cord-262786-otxpc46a	200	2	,	,	,
cord-262786-otxpc46a	200	3	the	the	DT
cord-262786-otxpc46a	200	4	administration	administration	NN
cord-262786-otxpc46a	200	5	of	of	IN
cord-262786-otxpc46a	200	6	intravenous	intravenous	JJ
cord-262786-otxpc46a	200	7	immunoglobulin	immunoglobulin	NN
cord-262786-otxpc46a	200	8	(	(	-LRB-
cord-262786-otxpc46a	200	9	IVIg	IVIg	NNP
cord-262786-otxpc46a	200	10	)	)	-RRB-
cord-262786-otxpc46a	200	11	resolves	resolve	VBZ
cord-262786-otxpc46a	200	12	symptoms	symptom	NNS
cord-262786-otxpc46a	200	13	and	and	CC
cord-262786-otxpc46a	200	14	improves	improve	VBZ
cord-262786-otxpc46a	200	15	the	the	DT
cord-262786-otxpc46a	200	16	outcomes	outcome	NNS
cord-262786-otxpc46a	200	17	in	in	IN
cord-262786-otxpc46a	200	18	post	post	JJ
cord-262786-otxpc46a	200	19	-	-	JJ
cord-262786-otxpc46a	200	20	SARS	SARS	NNP
cord-262786-otxpc46a	200	21	-	-	HYPH
cord-262786-otxpc46a	200	22	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	200	23	GBS	GBS	NNP
cord-262786-otxpc46a	200	24	patients	patient	NNS
cord-262786-otxpc46a	200	25	[	[	-LRB-
cord-262786-otxpc46a	200	26	59	59	CD
cord-262786-otxpc46a	200	27	]	]	-RRB-
cord-262786-otxpc46a	200	28	.	.	.
cord-262786-otxpc46a	201	1	Other	other	JJ
cord-262786-otxpc46a	201	2	plausible	plausible	JJ
cord-262786-otxpc46a	201	3	theories	theory	NNS
cord-262786-otxpc46a	201	4	may	may	MD
cord-262786-otxpc46a	201	5	underlie	underlie	VB
cord-262786-otxpc46a	201	6	the	the	DT
cord-262786-otxpc46a	201	7	development	development	NN
cord-262786-otxpc46a	201	8	of	of	IN
cord-262786-otxpc46a	201	9	GBS	GBS	NNP
cord-262786-otxpc46a	201	10	in	in	IN
cord-262786-otxpc46a	201	11	SARS	SARS	NNP
cord-262786-otxpc46a	201	12	-	-	HYPH
cord-262786-otxpc46a	201	13	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	201	14	.	.	.
cord-262786-otxpc46a	202	1	A	a	DT
cord-262786-otxpc46a	202	2	shift	shift	NN
cord-262786-otxpc46a	202	3	in	in	IN
cord-262786-otxpc46a	202	4	immune	immune	JJ
cord-262786-otxpc46a	202	5	response	response	NN
cord-262786-otxpc46a	202	6	toward	toward	IN
cord-262786-otxpc46a	202	7	pro	pro	JJ
cord-262786-otxpc46a	202	8	-	-	JJ
cord-262786-otxpc46a	202	9	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	202	10	cytokines	cytokine	NNS
cord-262786-otxpc46a	202	11	(	(	-LRB-
cord-262786-otxpc46a	202	12	e.g.	e.g.	RB
cord-262786-otxpc46a	202	13	,	,	,
cord-262786-otxpc46a	202	14	IL-1β	IL-1β	NNP
cord-262786-otxpc46a	202	15	,	,	,
cord-262786-otxpc46a	202	16	IL-6	IL-6	NNP
cord-262786-otxpc46a	202	17	,	,	,
cord-262786-otxpc46a	202	18	TNF	TNF	NNP
cord-262786-otxpc46a	202	19	-	-	HYPH
cord-262786-otxpc46a	202	20	α	α	NNP
cord-262786-otxpc46a	202	21	,	,	,
cord-262786-otxpc46a	202	22	and	and	CC
cord-262786-otxpc46a	202	23	IFN	IFN	NNP
cord-262786-otxpc46a	202	24	-	-	HYPH
cord-262786-otxpc46a	202	25	γ	γ	NNP
cord-262786-otxpc46a	202	26	)	)	-RRB-
cord-262786-otxpc46a	202	27	occurs	occur	VBZ
cord-262786-otxpc46a	202	28	in	in	IN
cord-262786-otxpc46a	202	29	acute	acute	JJ
cord-262786-otxpc46a	202	30	stages	stage	NNS
cord-262786-otxpc46a	202	31	of	of	IN
cord-262786-otxpc46a	202	32	GBS	GBS	NNP
cord-262786-otxpc46a	202	33	and	and	CC
cord-262786-otxpc46a	202	34	mediate	mediate	VB
cord-262786-otxpc46a	202	35	neural	neural	JJ
cord-262786-otxpc46a	202	36	degeneration	degeneration	NN
cord-262786-otxpc46a	202	37	[	[	-LRB-
cord-262786-otxpc46a	202	38	69	69	CD
cord-262786-otxpc46a	202	39	]	]	-RRB-
cord-262786-otxpc46a	202	40	.	.	.
cord-262786-otxpc46a	203	1	Similarly	similarly	RB
cord-262786-otxpc46a	203	2	,	,	,
cord-262786-otxpc46a	203	3	elevated	elevated	JJ
cord-262786-otxpc46a	203	4	levels	level	NNS
cord-262786-otxpc46a	203	5	of	of	IN
cord-262786-otxpc46a	203	6	IL-1β	il-1β	NN
cord-262786-otxpc46a	203	7	and	and	CC
cord-262786-otxpc46a	203	8	IL-6	IL-6	NNP
cord-262786-otxpc46a	203	9	are	be	VBP
cord-262786-otxpc46a	203	10	found	find	VBN
cord-262786-otxpc46a	203	11	in	in	IN
cord-262786-otxpc46a	203	12	the	the	DT
cord-262786-otxpc46a	203	13	CSF	CSF	NNP
cord-262786-otxpc46a	203	14	of	of	IN
cord-262786-otxpc46a	203	15	GBS	GBS	NNP
cord-262786-otxpc46a	203	16	patients	patient	NNS
cord-262786-otxpc46a	203	17	[	[	-LRB-
cord-262786-otxpc46a	203	18	69	69	CD
cord-262786-otxpc46a	203	19	]	]	-RRB-
cord-262786-otxpc46a	203	20	.	.	.
cord-262786-otxpc46a	204	1	So	so	RB
cord-262786-otxpc46a	204	2	,	,	,
cord-262786-otxpc46a	204	3	the	the	DT
cord-262786-otxpc46a	204	4	release	release	NN
cord-262786-otxpc46a	204	5	of	of	IN
cord-262786-otxpc46a	204	6	pro	pro	JJ
cord-262786-otxpc46a	204	7	-	-	JJ
cord-262786-otxpc46a	204	8	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	204	9	cytokines	cytokine	NNS
cord-262786-otxpc46a	204	10	in	in	IN
cord-262786-otxpc46a	204	11	SARS	SARS	NNP
cord-262786-otxpc46a	204	12	-	-	HYPH
cord-262786-otxpc46a	204	13	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	204	14	may	may	MD
cord-262786-otxpc46a	204	15	propagate	propagate	VB
cord-262786-otxpc46a	204	16	the	the	DT
cord-262786-otxpc46a	204	17	neurodegeneration	neurodegeneration	NN
cord-262786-otxpc46a	204	18	leading	lead	VBG
cord-262786-otxpc46a	204	19	to	to	IN
cord-262786-otxpc46a	204	20	GBS	GBS	NNP
cord-262786-otxpc46a	204	21	.	.	.
cord-262786-otxpc46a	205	1	Also	also	RB
cord-262786-otxpc46a	205	2	,	,	,
cord-262786-otxpc46a	205	3	the	the	DT
cord-262786-otxpc46a	205	4	SARS	SARS	NNP
cord-262786-otxpc46a	205	5	-	-	HYPH
cord-262786-otxpc46a	205	6	CoV-2-mediated	cov-2-mediate	VBN
cord-262786-otxpc46a	205	7	cytokine	cytokine	NN
cord-262786-otxpc46a	205	8	storm	storm	NN
cord-262786-otxpc46a	205	9	may	may	MD
cord-262786-otxpc46a	205	10	result	result	VB
cord-262786-otxpc46a	205	11	in	in	IN
cord-262786-otxpc46a	205	12	disruption	disruption	NN
cord-262786-otxpc46a	205	13	of	of	IN
cord-262786-otxpc46a	205	14	blood	blood	NN
cord-262786-otxpc46a	205	15	-	-	HYPH
cord-262786-otxpc46a	205	16	brain	brain	NN
cord-262786-otxpc46a	205	17	barrier	barrier	NN
cord-262786-otxpc46a	205	18	integrity	integrity	NN
cord-262786-otxpc46a	205	19	and	and	CC
cord-262786-otxpc46a	205	20	infiltration	infiltration	NN
cord-262786-otxpc46a	205	21	of	of	IN
cord-262786-otxpc46a	205	22	lymphocytes	lymphocyte	NNS
cord-262786-otxpc46a	205	23	leading	lead	VBG
cord-262786-otxpc46a	205	24	to	to	IN
cord-262786-otxpc46a	205	25	GBS	GBS	NNP
cord-262786-otxpc46a	205	26	[	[	-LRB-
cord-262786-otxpc46a	205	27	73	73	CD
cord-262786-otxpc46a	205	28	]	]	-RRB-
cord-262786-otxpc46a	205	29	.	.	.
cord-262786-otxpc46a	206	1	Recent	recent	JJ
cord-262786-otxpc46a	206	2	retrospective	retrospective	NN
cord-262786-otxpc46a	206	3	,	,	,
cord-262786-otxpc46a	206	4	case	case	NN
cord-262786-otxpc46a	206	5	series	series	NN
cord-262786-otxpc46a	206	6	,	,	,
cord-262786-otxpc46a	206	7	and	and	CC
cord-262786-otxpc46a	206	8	case	case	NN
cord-262786-otxpc46a	206	9	report	report	NN
cord-262786-otxpc46a	206	10	studies	study	NNS
cord-262786-otxpc46a	206	11	indicate	indicate	VBP
cord-262786-otxpc46a	206	12	that	that	IN
cord-262786-otxpc46a	206	13	SARS	SARS	NNP
cord-262786-otxpc46a	206	14	-	-	HYPH
cord-262786-otxpc46a	206	15	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	206	16	,	,	,
cord-262786-otxpc46a	206	17	as	as	RB
cord-262786-otxpc46a	206	18	well	well	RB
cord-262786-otxpc46a	206	19	as	as	IN
cord-262786-otxpc46a	206	20	SARS	SARS	NNP
cord-262786-otxpc46a	206	21	-	-	HYPH
cord-262786-otxpc46a	206	22	CoV	CoV	NNP
cord-262786-otxpc46a	206	23	and	and	CC
cord-262786-otxpc46a	206	24	MERS	MERS	NNP
cord-262786-otxpc46a	206	25	-	-	HYPH
cord-262786-otxpc46a	206	26	CoV	cov	NN
cord-262786-otxpc46a	206	27	patients	patient	NNS
cord-262786-otxpc46a	206	28	,	,	,
cord-262786-otxpc46a	206	29	is	be	VBZ
cord-262786-otxpc46a	206	30	prone	prone	JJ
cord-262786-otxpc46a	206	31	to	to	IN
cord-262786-otxpc46a	206	32	encephalopathy	encephalopathy	NN
cord-262786-otxpc46a	206	33	and	and	CC
cord-262786-otxpc46a	206	34	seizure	seizure	NN
cord-262786-otxpc46a	206	35	[	[	-LRB-
cord-262786-otxpc46a	206	36	88	88	CD
cord-262786-otxpc46a	206	37	]	]	-RRB-
cord-262786-otxpc46a	206	38	.	.	.
cord-262786-otxpc46a	207	1	Brain	Brain	NNP
cord-262786-otxpc46a	207	2	MRI	MRI	NNP
cord-262786-otxpc46a	207	3	studies	study	NNS
cord-262786-otxpc46a	207	4	of	of	IN
cord-262786-otxpc46a	207	5	these	these	DT
cord-262786-otxpc46a	207	6	patients	patient	NNS
cord-262786-otxpc46a	207	7	demonstrate	demonstrate	VBP
cord-262786-otxpc46a	207	8	multifocal	multifocal	JJ
cord-262786-otxpc46a	207	9	involvement	involvement	NN
cord-262786-otxpc46a	207	10	of	of	IN
cord-262786-otxpc46a	207	11	cortex	cortex	NN
cord-262786-otxpc46a	207	12	and	and	CC
cord-262786-otxpc46a	207	13	white	white	JJ
cord-262786-otxpc46a	207	14	matter	matter	NN
cord-262786-otxpc46a	207	15	(	(	-LRB-
cord-262786-otxpc46a	207	16	including	include	VBG
cord-262786-otxpc46a	207	17	periventricular	periventricular	NNP
cord-262786-otxpc46a	207	18	areas	area	NNS
cord-262786-otxpc46a	207	19	)	)	-RRB-
cord-262786-otxpc46a	207	20	,	,	,
cord-262786-otxpc46a	207	21	along	along	IN
cord-262786-otxpc46a	207	22	with	with	IN
cord-262786-otxpc46a	207	23	multiple	multiple	JJ
cord-262786-otxpc46a	207	24	hyperintense	hyperintense	NN
cord-262786-otxpc46a	207	25	areas	area	NNS
cord-262786-otxpc46a	207	26	in	in	IN
cord-262786-otxpc46a	207	27	T2-weighted	t2-weighted	JJ
cord-262786-otxpc46a	207	28	and	and	CC
cord-262786-otxpc46a	207	29	FLAIR	flair	NN
cord-262786-otxpc46a	207	30	images	image	NNS
cord-262786-otxpc46a	207	31	in	in	IN
cord-262786-otxpc46a	207	32	temporal	temporal	JJ
cord-262786-otxpc46a	207	33	,	,	,
cord-262786-otxpc46a	207	34	frontal	frontal	JJ
cord-262786-otxpc46a	207	35	,	,	,
cord-262786-otxpc46a	207	36	and	and	CC
cord-262786-otxpc46a	207	37	occipital	occipital	JJ
cord-262786-otxpc46a	207	38	lobes	lobe	NNS
cord-262786-otxpc46a	207	39	and	and	CC
cord-262786-otxpc46a	207	40	hippocampus	hippocampus	NN
cord-262786-otxpc46a	207	41	(	(	-LRB-
cord-262786-otxpc46a	207	42	Table	table	NN
cord-262786-otxpc46a	207	43	2	2	CD
cord-262786-otxpc46a	207	44	)	)	-RRB-
cord-262786-otxpc46a	207	45	[	[	-LRB-
cord-262786-otxpc46a	207	46	74	74	CD
cord-262786-otxpc46a	207	47	,	,	,
cord-262786-otxpc46a	207	48	89	89	CD
cord-262786-otxpc46a	207	49	]	]	-RRB-
cord-262786-otxpc46a	207	50	.	.	.
cord-262786-otxpc46a	208	1	Consequences	consequence	NNS
cord-262786-otxpc46a	208	2	of	of	IN
cord-262786-otxpc46a	208	3	SARS	SARS	NNP
cord-262786-otxpc46a	208	4	-	-	HYPH
cord-262786-otxpc46a	208	5	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	208	6	infection	infection	NN
cord-262786-otxpc46a	208	7	,	,	,
cord-262786-otxpc46a	208	8	including	include	VBG
cord-262786-otxpc46a	208	9	organ	organ	NN
cord-262786-otxpc46a	208	10	failure	failure	NN
cord-262786-otxpc46a	208	11	,	,	,
cord-262786-otxpc46a	208	12	hypoxia	hypoxia	NN
cord-262786-otxpc46a	208	13	,	,	,
cord-262786-otxpc46a	208	14	metabolic	metabolic	JJ
cord-262786-otxpc46a	208	15	disturbance	disturbance	NN
cord-262786-otxpc46a	208	16	,	,	,
cord-262786-otxpc46a	208	17	and	and	CC
cord-262786-otxpc46a	208	18	direct	direct	JJ
cord-262786-otxpc46a	208	19	viral	viral	JJ
cord-262786-otxpc46a	208	20	invasion	invasion	NN
cord-262786-otxpc46a	208	21	into	into	IN
cord-262786-otxpc46a	208	22	the	the	DT
cord-262786-otxpc46a	208	23	CNS	CNS	NNP
cord-262786-otxpc46a	208	24	,	,	,
cord-262786-otxpc46a	208	25	are	be	VBP
cord-262786-otxpc46a	208	26	proposed	propose	VBN
cord-262786-otxpc46a	208	27	to	to	TO
cord-262786-otxpc46a	208	28	explain	explain	VB
cord-262786-otxpc46a	208	29	the	the	DT
cord-262786-otxpc46a	208	30	observations	observation	NNS
cord-262786-otxpc46a	208	31	of	of	IN
cord-262786-otxpc46a	208	32	encephalopathy	encephalopathy	NN
cord-262786-otxpc46a	208	33	and	and	CC
cord-262786-otxpc46a	208	34	seizure	seizure	NN
cord-262786-otxpc46a	208	35	in	in	IN
cord-262786-otxpc46a	208	36	these	these	DT
cord-262786-otxpc46a	208	37	patients	patient	NNS
cord-262786-otxpc46a	208	38	[	[	-LRB-
cord-262786-otxpc46a	208	39	88	88	CD
cord-262786-otxpc46a	208	40	]	]	-RRB-
cord-262786-otxpc46a	208	41	.	.	.
cord-262786-otxpc46a	209	1	However	however	RB
cord-262786-otxpc46a	209	2	,	,	,
cord-262786-otxpc46a	209	3	most	most	JJS
cord-262786-otxpc46a	209	4	findings	finding	NNS
cord-262786-otxpc46a	209	5	are	be	VBP
cord-262786-otxpc46a	209	6	in	in	IN
cord-262786-otxpc46a	209	7	favor	favor	NN
cord-262786-otxpc46a	209	8	of	of	IN
cord-262786-otxpc46a	209	9	immune	immune	NN
cord-262786-otxpc46a	209	10	-	-	HYPH
cord-262786-otxpc46a	209	11	mediated	mediate	VBN
cord-262786-otxpc46a	209	12	encephalopathy	encephalopathy	NN
cord-262786-otxpc46a	209	13	and	and	CC
cord-262786-otxpc46a	209	14	seizure	seizure	NN
cord-262786-otxpc46a	209	15	.	.	.
cord-262786-otxpc46a	210	1	Except	except	IN
cord-262786-otxpc46a	210	2	for	for	IN
cord-262786-otxpc46a	210	3	two	two	CD
cord-262786-otxpc46a	210	4	case	case	NN
cord-262786-otxpc46a	210	5	reports	report	NNS
cord-262786-otxpc46a	210	6	,	,	,
cord-262786-otxpc46a	210	7	all	all	PDT
cord-262786-otxpc46a	210	8	the	the	DT
cord-262786-otxpc46a	210	9	remaining	remain	VBG
cord-262786-otxpc46a	210	10	studies	study	NNS
cord-262786-otxpc46a	210	11	are	be	VBP
cord-262786-otxpc46a	210	12	not	not	RB
cord-262786-otxpc46a	210	13	able	able	JJ
cord-262786-otxpc46a	210	14	to	to	TO
cord-262786-otxpc46a	210	15	detect	detect	VB
cord-262786-otxpc46a	210	16	the	the	DT
cord-262786-otxpc46a	210	17	viral	viral	JJ
cord-262786-otxpc46a	210	18	genome	genome	NN
cord-262786-otxpc46a	210	19	in	in	IN
cord-262786-otxpc46a	210	20	the	the	DT
cord-262786-otxpc46a	210	21	CSF	csf	NN
cord-262786-otxpc46a	210	22	of	of	IN
cord-262786-otxpc46a	210	23	these	these	DT
cord-262786-otxpc46a	210	24	patients	patient	NNS
cord-262786-otxpc46a	210	25	[	[	-LRB-
cord-262786-otxpc46a	210	26	41	41	CD
cord-262786-otxpc46a	210	27	]	]	-RRB-
cord-262786-otxpc46a	210	28	.	.	.
cord-262786-otxpc46a	211	1	Seemingly	seemingly	RB
cord-262786-otxpc46a	211	2	,	,	,
cord-262786-otxpc46a	211	3	most	most	JJS
cord-262786-otxpc46a	211	4	patients	patient	NNS
cord-262786-otxpc46a	211	5	exhibit	exhibit	VBP
cord-262786-otxpc46a	211	6	a	a	DT
cord-262786-otxpc46a	211	7	dramatic	dramatic	JJ
cord-262786-otxpc46a	211	8	response	response	NN
cord-262786-otxpc46a	211	9	to	to	IN
cord-262786-otxpc46a	211	10	plasmapheresis	plasmapheresis	NN
cord-262786-otxpc46a	211	11	and	and	CC
cord-262786-otxpc46a	211	12	steroid	steroid	NN
cord-262786-otxpc46a	211	13	therapy	therapy	NN
cord-262786-otxpc46a	211	14	,	,	,
cord-262786-otxpc46a	211	15	which	which	WDT
cord-262786-otxpc46a	211	16	indicates	indicate	VBZ
cord-262786-otxpc46a	211	17	a	a	DT
cord-262786-otxpc46a	211	18	role	role	NN
cord-262786-otxpc46a	211	19	for	for	IN
cord-262786-otxpc46a	211	20	autoimmune	autoimmune	NN
cord-262786-otxpc46a	211	21	-	-	HYPH
cord-262786-otxpc46a	211	22	mediated	mediate	VBN
cord-262786-otxpc46a	211	23	injury	injury	NN
cord-262786-otxpc46a	211	24	[	[	-LRB-
cord-262786-otxpc46a	211	25	23	23	CD
cord-262786-otxpc46a	211	26	]	]	-RRB-
cord-262786-otxpc46a	211	27	.	.	.
cord-262786-otxpc46a	212	1	As	as	IN
cord-262786-otxpc46a	212	2	mentioned	mention	VBN
cord-262786-otxpc46a	212	3	before	before	RB
cord-262786-otxpc46a	212	4	,	,	,
cord-262786-otxpc46a	212	5	the	the	DT
cord-262786-otxpc46a	212	6	aberrant	aberrant	JJ
cord-262786-otxpc46a	212	7	release	release	NN
cord-262786-otxpc46a	212	8	of	of	IN
cord-262786-otxpc46a	212	9	pro	pro	JJ
cord-262786-otxpc46a	212	10	-	-	JJ
cord-262786-otxpc46a	212	11	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	212	12	cytokines	cytokine	NNS
cord-262786-otxpc46a	212	13	like	like	IN
cord-262786-otxpc46a	212	14	IL-1β	il-1β	NN
cord-262786-otxpc46a	212	15	,	,	,
cord-262786-otxpc46a	212	16	IL-6	IL-6	NNP
cord-262786-otxpc46a	212	17	,	,	,
cord-262786-otxpc46a	212	18	and	and	CC
cord-262786-otxpc46a	212	19	TNF	TNF	NNP
cord-262786-otxpc46a	212	20	-	-	HYPH
cord-262786-otxpc46a	212	21	α	α	NNP
cord-262786-otxpc46a	212	22	disrupts	disrupt	VBZ
cord-262786-otxpc46a	212	23	blood	blood	NN
cord-262786-otxpc46a	212	24	-	-	HYPH
cord-262786-otxpc46a	212	25	brain	brain	NN
cord-262786-otxpc46a	212	26	barrier	barrier	NN
cord-262786-otxpc46a	212	27	permeability	permeability	NN
cord-262786-otxpc46a	212	28	,	,	,
cord-262786-otxpc46a	212	29	and	and	CC
cord-262786-otxpc46a	212	30	the	the	DT
cord-262786-otxpc46a	212	31	resulting	result	VBG
cord-262786-otxpc46a	212	32	infiltration	infiltration	NN
cord-262786-otxpc46a	212	33	of	of	IN
cord-262786-otxpc46a	212	34	WBCs	wbc	NNS
cord-262786-otxpc46a	212	35	and	and	CC
cord-262786-otxpc46a	212	36	activation	activation	NN
cord-262786-otxpc46a	212	37	of	of	IN
cord-262786-otxpc46a	212	38	microglia	microglia	NN
cord-262786-otxpc46a	212	39	and	and	CC
cord-262786-otxpc46a	212	40	astrocytes	astrocyte	VBZ
cord-262786-otxpc46a	212	41	damages	damage	NNS
cord-262786-otxpc46a	212	42	neurons	neuron	NNS
cord-262786-otxpc46a	212	43	and	and	CC
cord-262786-otxpc46a	212	44	glial	glial	JJ
cord-262786-otxpc46a	212	45	cells	cell	NNS
cord-262786-otxpc46a	212	46	[	[	-LRB-
cord-262786-otxpc46a	212	47	24	24	CD
cord-262786-otxpc46a	212	48	,	,	,
cord-262786-otxpc46a	212	49	41	41	CD
cord-262786-otxpc46a	212	50	]	]	-RRB-
cord-262786-otxpc46a	212	51	.	.	.
cord-262786-otxpc46a	213	1	Also	also	RB
cord-262786-otxpc46a	213	2	,	,	,
cord-262786-otxpc46a	213	3	it	-PRON-	PRP
cord-262786-otxpc46a	213	4	is	be	VBZ
cord-262786-otxpc46a	213	5	speculated	speculate	VBN
cord-262786-otxpc46a	213	6	that	that	IN
cord-262786-otxpc46a	213	7	the	the	DT
cord-262786-otxpc46a	213	8	viralmediated	viralmediated	JJ
cord-262786-otxpc46a	213	9	production	production	NN
cord-262786-otxpc46a	213	10	of	of	IN
cord-262786-otxpc46a	213	11	autoantibodies	autoantibody	NNS
cord-262786-otxpc46a	213	12	against	against	IN
cord-262786-otxpc46a	213	13	glial	glial	JJ
cord-262786-otxpc46a	213	14	cells	cell	NNS
cord-262786-otxpc46a	213	15	might	may	MD
cord-262786-otxpc46a	213	16	be	be	VB
cord-262786-otxpc46a	213	17	responsible	responsible	JJ
cord-262786-otxpc46a	213	18	for	for	IN
cord-262786-otxpc46a	213	19	neural	neural	JJ
cord-262786-otxpc46a	213	20	injury	injury	NN
cord-262786-otxpc46a	213	21	[	[	-LRB-
cord-262786-otxpc46a	213	22	74	74	CD
cord-262786-otxpc46a	213	23	]	]	-RRB-
cord-262786-otxpc46a	213	24	.	.	.
cord-262786-otxpc46a	214	1	Transgenic	transgenic	JJ
cord-262786-otxpc46a	214	2	mice	mouse	NNS
cord-262786-otxpc46a	214	3	infected	infect	VBN
cord-262786-otxpc46a	214	4	by	by	IN
cord-262786-otxpc46a	214	5	SARS	SARS	NNP
cord-262786-otxpc46a	214	6	-	-	HYPH
cord-262786-otxpc46a	214	7	CoV	CoV	NNP
cord-262786-otxpc46a	214	8	and	and	CC
cord-262786-otxpc46a	214	9	MERS	MERS	NNP
cord-262786-otxpc46a	214	10	-	-	HYPH
cord-262786-otxpc46a	214	11	CoV	CoV	NNP
cord-262786-otxpc46a	214	12	exhibit	exhibit	NN
cord-262786-otxpc46a	214	13	brainstem	brainstem	NN
cord-262786-otxpc46a	214	14	involvement	involvement	NN
cord-262786-otxpc46a	214	15	due	due	JJ
cord-262786-otxpc46a	214	16	to	to	IN
cord-262786-otxpc46a	214	17	trans	trans	JJ
cord-262786-otxpc46a	214	18	-	-	JJ
cord-262786-otxpc46a	214	19	synaptic	synaptic	JJ
cord-262786-otxpc46a	214	20	projection	projection	NN
cord-262786-otxpc46a	214	21	of	of	IN
cord-262786-otxpc46a	214	22	the	the	DT
cord-262786-otxpc46a	214	23	virus	virus	NN
cord-262786-otxpc46a	214	24	throughout	throughout	IN
cord-262786-otxpc46a	214	25	the	the	DT
cord-262786-otxpc46a	214	26	olfactory	olfactory	JJ
cord-262786-otxpc46a	214	27	epithelium	epithelium	NN
cord-262786-otxpc46a	214	28	,	,	,
cord-262786-otxpc46a	214	29	olfactory	olfactory	JJ
cord-262786-otxpc46a	214	30	bulb	bulb	NN
cord-262786-otxpc46a	214	31	,	,	,
cord-262786-otxpc46a	214	32	thalamus	thalamus	NN
cord-262786-otxpc46a	214	33	,	,	,
cord-262786-otxpc46a	214	34	and	and	CC
cord-262786-otxpc46a	214	35	finally	finally	RB
cord-262786-otxpc46a	214	36	the	the	DT
cord-262786-otxpc46a	214	37	brainstem	brainstem	NN
cord-262786-otxpc46a	214	38	[	[	-LRB-
cord-262786-otxpc46a	214	39	16	16	CD
cord-262786-otxpc46a	214	40	]	]	-RRB-
cord-262786-otxpc46a	214	41	.	.	.
cord-262786-otxpc46a	215	1	The	the	DT
cord-262786-otxpc46a	215	2	virus	virus	NN
cord-262786-otxpc46a	215	3	might	may	MD
cord-262786-otxpc46a	215	4	target	target	VB
cord-262786-otxpc46a	215	5	the	the	DT
cord-262786-otxpc46a	215	6	primary	primary	JJ
cord-262786-otxpc46a	215	7	respiratory	respiratory	JJ
cord-262786-otxpc46a	215	8	oscillator	oscillator	NN
cord-262786-otxpc46a	215	9	(	(	-LRB-
cord-262786-otxpc46a	215	10	known	know	VBN
cord-262786-otxpc46a	215	11	as	as	IN
cord-262786-otxpc46a	215	12	pre	pre	JJ
cord-262786-otxpc46a	215	13	-	-	JJ
cord-262786-otxpc46a	215	14	Bötzinger	Bötzinger	NNP
cord-262786-otxpc46a	215	15	complex	complex	NN
cord-262786-otxpc46a	215	16	)	)	-RRB-
cord-262786-otxpc46a	215	17	in	in	IN
cord-262786-otxpc46a	215	18	the	the	DT
cord-262786-otxpc46a	215	19	brainstem	brainstem	NN
cord-262786-otxpc46a	215	20	and	and	CC
cord-262786-otxpc46a	215	21	result	result	VB
cord-262786-otxpc46a	215	22	in	in	IN
cord-262786-otxpc46a	215	23	respiratory	respiratory	JJ
cord-262786-otxpc46a	215	24	failure	failure	NN
cord-262786-otxpc46a	215	25	in	in	IN
cord-262786-otxpc46a	215	26	these	these	DT
cord-262786-otxpc46a	215	27	animal	animal	NN
cord-262786-otxpc46a	215	28	models	model	NNS
cord-262786-otxpc46a	215	29	[	[	-LRB-
cord-262786-otxpc46a	215	30	16	16	CD
cord-262786-otxpc46a	215	31	]	]	-RRB-
cord-262786-otxpc46a	215	32	.	.	.
cord-262786-otxpc46a	216	1	Seemingly	seemingly	RB
cord-262786-otxpc46a	216	2	,	,	,
cord-262786-otxpc46a	216	3	acute	acute	JJ
cord-262786-otxpc46a	216	4	respiratory	respiratory	JJ
cord-262786-otxpc46a	216	5	failure	failure	NN
cord-262786-otxpc46a	216	6	due	due	IN
cord-262786-otxpc46a	216	7	to	to	IN
cord-262786-otxpc46a	216	8	brainstem	brainstem	NN
cord-262786-otxpc46a	216	9	dysfunction	dysfunction	NN
cord-262786-otxpc46a	216	10	is	be	VBZ
cord-262786-otxpc46a	216	11	reported	report	VBN
cord-262786-otxpc46a	216	12	in	in	IN
cord-262786-otxpc46a	216	13	SARS	SARS	NNP
cord-262786-otxpc46a	216	14	-	-	HYPH
cord-262786-otxpc46a	216	15	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	216	16	patients	patient	NNS
cord-262786-otxpc46a	216	17	[	[	-LRB-
cord-262786-otxpc46a	216	18	90	90	CD
cord-262786-otxpc46a	216	19	]	]	-RRB-
cord-262786-otxpc46a	216	20	.	.	.
cord-262786-otxpc46a	217	1	Also	also	RB
cord-262786-otxpc46a	217	2	,	,	,
cord-262786-otxpc46a	217	3	a	a	DT
cord-262786-otxpc46a	217	4	recent	recent	JJ
cord-262786-otxpc46a	217	5	case	case	NN
cord-262786-otxpc46a	217	6	study	study	NN
cord-262786-otxpc46a	217	7	reports	report	VBZ
cord-262786-otxpc46a	217	8	post	post	JJ
cord-262786-otxpc46a	217	9	-	-	JJ
cord-262786-otxpc46a	217	10	infectious	infectious	JJ
cord-262786-otxpc46a	217	11	brainstem	brainstem	NN
cord-262786-otxpc46a	217	12	involvement	involvement	NN
cord-262786-otxpc46a	217	13	presenting	present	VBG
cord-262786-otxpc46a	217	14	with	with	IN
cord-262786-otxpc46a	217	15	involuntary	involuntary	JJ
cord-262786-otxpc46a	217	16	movements	movement	NNS
cord-262786-otxpc46a	217	17	,	,	,
cord-262786-otxpc46a	217	18	myoclonus	myoclonus	FW
cord-262786-otxpc46a	217	19	,	,	,
cord-262786-otxpc46a	217	20	and	and	CC
cord-262786-otxpc46a	217	21	hyperekplexia	hyperekplexia	NNP
cord-262786-otxpc46a	217	22	after	after	IN
cord-262786-otxpc46a	217	23	gradual	gradual	JJ
cord-262786-otxpc46a	217	24	respiratory	respiratory	JJ
cord-262786-otxpc46a	217	25	symptom	symptom	NN
cord-262786-otxpc46a	217	26	relief	relief	NN
cord-262786-otxpc46a	217	27	in	in	IN
cord-262786-otxpc46a	217	28	a	a	DT
cord-262786-otxpc46a	217	29	case	case	NN
cord-262786-otxpc46a	217	30	of	of	IN
cord-262786-otxpc46a	217	31	SARS	SARS	NNP
cord-262786-otxpc46a	217	32	-	-	HYPH
cord-262786-otxpc46a	217	33	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	217	34	[	[	-LRB-
cord-262786-otxpc46a	217	35	91	91	CD
cord-262786-otxpc46a	217	36	]	]	-RRB-
cord-262786-otxpc46a	217	37	.	.	.
cord-262786-otxpc46a	218	1	Postmortem	postmortem	JJ
cord-262786-otxpc46a	218	2	autopsy	autopsy	JJ
cord-262786-otxpc46a	218	3	studies	study	NNS
cord-262786-otxpc46a	218	4	elucidate	elucidate	VBP
cord-262786-otxpc46a	218	5	areas	area	NNS
cord-262786-otxpc46a	218	6	of	of	IN
cord-262786-otxpc46a	218	7	hyperemia	hyperemia	NN
cord-262786-otxpc46a	218	8	and	and	CC
cord-262786-otxpc46a	218	9	edema	edema	NN
cord-262786-otxpc46a	218	10	and	and	CC
cord-262786-otxpc46a	218	11	neurodegeneration	neurodegeneration	NN
cord-262786-otxpc46a	218	12	in	in	IN
cord-262786-otxpc46a	218	13	the	the	DT
cord-262786-otxpc46a	218	14	brainstem	brainstem	NN
cord-262786-otxpc46a	218	15	[	[	-LRB-
cord-262786-otxpc46a	218	16	90	90	CD
cord-262786-otxpc46a	218	17	]	]	-RRB-
cord-262786-otxpc46a	218	18	.	.	.
cord-262786-otxpc46a	219	1	MRI	MRI	NNP
cord-262786-otxpc46a	219	2	findings	finding	NNS
cord-262786-otxpc46a	219	3	in	in	IN
cord-262786-otxpc46a	219	4	a	a	DT
cord-262786-otxpc46a	219	5	case	case	NN
cord-262786-otxpc46a	219	6	of	of	IN
cord-262786-otxpc46a	219	7	brainstem	brainstem	NN
cord-262786-otxpc46a	219	8	involvement	involvement	NN
cord-262786-otxpc46a	219	9	demonstrate	demonstrate	VBP
cord-262786-otxpc46a	219	10	high	high	JJ
cord-262786-otxpc46a	219	11	signal	signal	NN
cord-262786-otxpc46a	219	12	lesions	lesion	NNS
cord-262786-otxpc46a	219	13	in	in	IN
cord-262786-otxpc46a	219	14	bilateral	bilateral	JJ
cord-262786-otxpc46a	219	15	pons	pon	NNS
cord-262786-otxpc46a	219	16	in	in	IN
cord-262786-otxpc46a	219	17	T2-FLAIR	t2-flair	CD
cord-262786-otxpc46a	219	18	images	image	NNS
cord-262786-otxpc46a	219	19	(	(	-LRB-
cord-262786-otxpc46a	219	20	Table	table	NN
cord-262786-otxpc46a	219	21	2	2	CD
cord-262786-otxpc46a	219	22	)	)	-RRB-
cord-262786-otxpc46a	219	23	[	[	-LRB-
cord-262786-otxpc46a	219	24	92	92	CD
cord-262786-otxpc46a	219	25	]	]	-RRB-
cord-262786-otxpc46a	219	26	.	.	.
cord-262786-otxpc46a	220	1	These	these	DT
cord-262786-otxpc46a	220	2	findings	finding	NNS
cord-262786-otxpc46a	220	3	are	be	VBP
cord-262786-otxpc46a	220	4	in	in	IN
cord-262786-otxpc46a	220	5	favor	favor	NN
cord-262786-otxpc46a	220	6	of	of	IN
cord-262786-otxpc46a	220	7	brainstem	brainstem	NN
cord-262786-otxpc46a	220	8	involvement	involvement	NN
cord-262786-otxpc46a	220	9	due	due	JJ
cord-262786-otxpc46a	220	10	to	to	IN
cord-262786-otxpc46a	220	11	direct	direct	JJ
cord-262786-otxpc46a	220	12	viral	viral	JJ
cord-262786-otxpc46a	220	13	invasion	invasion	NN
cord-262786-otxpc46a	220	14	.	.	.
cord-262786-otxpc46a	221	1	However	however	RB
cord-262786-otxpc46a	221	2	,	,	,
cord-262786-otxpc46a	221	3	the	the	DT
cord-262786-otxpc46a	221	4	absence	absence	NN
cord-262786-otxpc46a	221	5	of	of	IN
cord-262786-otxpc46a	221	6	viral	viral	JJ
cord-262786-otxpc46a	221	7	genome	genome	NN
cord-262786-otxpc46a	221	8	in	in	IN
cord-262786-otxpc46a	221	9	CSF	CSF	NNP
cord-262786-otxpc46a	221	10	along	along	IN
cord-262786-otxpc46a	221	11	with	with	IN
cord-262786-otxpc46a	221	12	the	the	DT
cord-262786-otxpc46a	221	13	presence	presence	NN
cord-262786-otxpc46a	221	14	of	of	IN
cord-262786-otxpc46a	221	15	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	221	16	mediators	mediator	NNS
cord-262786-otxpc46a	221	17	(	(	-LRB-
cord-262786-otxpc46a	221	18	namely	namely	RB
cord-262786-otxpc46a	221	19	TNF	TNF	NNP
cord-262786-otxpc46a	221	20	-	-	HYPH
cord-262786-otxpc46a	221	21	α	α	NNP
cord-262786-otxpc46a	221	22	and	and	CC
cord-262786-otxpc46a	221	23	interleukin-8	interleukin-8	NNP
cord-262786-otxpc46a	221	24	(	(	-LRB-
cord-262786-otxpc46a	221	25	IL-8	IL-8	NNP
cord-262786-otxpc46a	221	26	)	)	-RRB-
cord-262786-otxpc46a	221	27	)	)	-RRB-
cord-262786-otxpc46a	221	28	and	and	CC
cord-262786-otxpc46a	221	29	pleocytosis	pleocytosis	NNP
cord-262786-otxpc46a	221	30	in	in	IN
cord-262786-otxpc46a	221	31	CSF	CSF	NNP
cord-262786-otxpc46a	221	32	in	in	IN
cord-262786-otxpc46a	221	33	a	a	DT
cord-262786-otxpc46a	221	34	group	group	NN
cord-262786-otxpc46a	221	35	of	of	IN
cord-262786-otxpc46a	221	36	patients	patient	NNS
cord-262786-otxpc46a	221	37	with	with	IN
cord-262786-otxpc46a	221	38	brainstem	brainstem	NN
cord-262786-otxpc46a	221	39	dysfunction	dysfunction	NN
cord-262786-otxpc46a	221	40	suggests	suggest	VBZ
cord-262786-otxpc46a	221	41	that	that	IN
cord-262786-otxpc46a	221	42	the	the	DT
cord-262786-otxpc46a	221	43	aberrant	aberrant	JJ
cord-262786-otxpc46a	221	44	immune	immune	JJ
cord-262786-otxpc46a	221	45	response	response	NN
cord-262786-otxpc46a	221	46	might	may	MD
cord-262786-otxpc46a	221	47	underlie	underlie	VB
cord-262786-otxpc46a	221	48	the	the	DT
cord-262786-otxpc46a	221	49	brainstem	brainstem	NN
cord-262786-otxpc46a	221	50	dysfunction	dysfunction	NN
cord-262786-otxpc46a	221	51	in	in	IN
cord-262786-otxpc46a	221	52	SARS	SARS	NNP
cord-262786-otxpc46a	221	53	-	-	HYPH
cord-262786-otxpc46a	221	54	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	221	55	[	[	-LRB-
cord-262786-otxpc46a	221	56	90	90	CD
cord-262786-otxpc46a	221	57	]	]	-RRB-
cord-262786-otxpc46a	221	58	.	.	.
cord-262786-otxpc46a	222	1	SARS	SARS	NNP
cord-262786-otxpc46a	222	2	-	-	HYPH
cord-262786-otxpc46a	222	3	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	222	4	pandemic	pandemic	NN
cord-262786-otxpc46a	222	5	,	,	,
cord-262786-otxpc46a	222	6	beginning	begin	VBG
cord-262786-otxpc46a	222	7	in	in	IN
cord-262786-otxpc46a	222	8	December	December	NNP
cord-262786-otxpc46a	222	9	2019	2019	CD
cord-262786-otxpc46a	222	10	,	,	,
cord-262786-otxpc46a	222	11	has	have	VBZ
cord-262786-otxpc46a	222	12	now	now	RB
cord-262786-otxpc46a	222	13	become	become	VBN
cord-262786-otxpc46a	222	14	a	a	DT
cord-262786-otxpc46a	222	15	global	global	JJ
cord-262786-otxpc46a	222	16	concern	concern	NN
cord-262786-otxpc46a	222	17	.	.	.
cord-262786-otxpc46a	223	1	Although	although	IN
cord-262786-otxpc46a	223	2	the	the	DT
cord-262786-otxpc46a	223	3	acute	acute	JJ
cord-262786-otxpc46a	223	4	respiratory	respiratory	JJ
cord-262786-otxpc46a	223	5	manifestations	manifestation	NNS
cord-262786-otxpc46a	223	6	of	of	IN
cord-262786-otxpc46a	223	7	the	the	DT
cord-262786-otxpc46a	223	8	disease	disease	NN
cord-262786-otxpc46a	223	9	are	be	VBP
cord-262786-otxpc46a	223	10	greatly	greatly	RB
cord-262786-otxpc46a	223	11	considered	consider	VBN
cord-262786-otxpc46a	223	12	,	,	,
cord-262786-otxpc46a	223	13	reports	report	NNS
cord-262786-otxpc46a	223	14	of	of	IN
cord-262786-otxpc46a	223	15	neurologic	neurologic	JJ
cord-262786-otxpc46a	223	16	sequelae	sequela	NNS
cord-262786-otxpc46a	223	17	are	be	VBP
cord-262786-otxpc46a	223	18	dramatically	dramatically	RB
cord-262786-otxpc46a	223	19	increasing	increase	VBG
cord-262786-otxpc46a	223	20	.	.	.
cord-262786-otxpc46a	224	1	A	a	DT
cord-262786-otxpc46a	224	2	recent	recent	JJ
cord-262786-otxpc46a	224	3	cohort	cohort	NN
cord-262786-otxpc46a	224	4	study	study	NN
cord-262786-otxpc46a	224	5	of	of	IN
cord-262786-otxpc46a	224	6	SARS	SARS	NNP
cord-262786-otxpc46a	224	7	-	-	HYPH
cord-262786-otxpc46a	224	8	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	224	9	patients	patient	NNS
cord-262786-otxpc46a	224	10	reported	report	VBD
cord-262786-otxpc46a	224	11	a	a	DT
cord-262786-otxpc46a	224	12	4.3	4.3	CD
cord-262786-otxpc46a	224	13	%	%	NN
cord-262786-otxpc46a	224	14	prevalence	prevalence	NN
cord-262786-otxpc46a	224	15	for	for	IN
cord-262786-otxpc46a	224	16	neurologic	neurologic	JJ
cord-262786-otxpc46a	224	17	symptoms	symptom	NNS
cord-262786-otxpc46a	224	18	,	,	,
cord-262786-otxpc46a	224	19	other	other	JJ
cord-262786-otxpc46a	224	20	than	than	IN
cord-262786-otxpc46a	224	21	anosmia	anosmia	NN
cord-262786-otxpc46a	224	22	and	and	CC
cord-262786-otxpc46a	224	23	headache	headache	NN
cord-262786-otxpc46a	224	24	[	[	-LRB-
cord-262786-otxpc46a	224	25	93	93	CD
cord-262786-otxpc46a	224	26	]	]	-RRB-
cord-262786-otxpc46a	224	27	.	.	.
cord-262786-otxpc46a	225	1	Also	also	RB
cord-262786-otxpc46a	225	2	,	,	,
cord-262786-otxpc46a	225	3	para	para	NN
cord-262786-otxpc46a	225	4	-	-	HYPH
cord-262786-otxpc46a	225	5	clinic	clinic	NN
cord-262786-otxpc46a	225	6	investigations	investigation	NNS
cord-262786-otxpc46a	225	7	support	support	VBP
cord-262786-otxpc46a	225	8	the	the	DT
cord-262786-otxpc46a	225	9	idea	idea	NN
cord-262786-otxpc46a	225	10	of	of	IN
cord-262786-otxpc46a	225	11	post	post	JJ
cord-262786-otxpc46a	225	12	-	-	JJ
cord-262786-otxpc46a	225	13	SARS	SARS	NNP
cord-262786-otxpc46a	225	14	-	-	HYPH
cord-262786-otxpc46a	225	15	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	225	16	CNS	CNS	NNP
cord-262786-otxpc46a	225	17	involvement	involvement	NN
cord-262786-otxpc46a	225	18	(	(	-LRB-
cord-262786-otxpc46a	225	19	Table	table	NN
cord-262786-otxpc46a	225	20	2	2	CD
cord-262786-otxpc46a	225	21	)	)	-RRB-
cord-262786-otxpc46a	225	22	.	.	.
cord-262786-otxpc46a	226	1	Although	although	IN
cord-262786-otxpc46a	226	2	the	the	DT
cord-262786-otxpc46a	226	3	CNS	CNS	NNP
cord-262786-otxpc46a	226	4	complications	complication	NNS
cord-262786-otxpc46a	226	5	might	may	MD
cord-262786-otxpc46a	226	6	be	be	VB
cord-262786-otxpc46a	226	7	a	a	DT
cord-262786-otxpc46a	226	8	consequence	consequence	NN
cord-262786-otxpc46a	226	9	of	of	IN
cord-262786-otxpc46a	226	10	direct	direct	JJ
cord-262786-otxpc46a	226	11	viral	viral	JJ
cord-262786-otxpc46a	226	12	invasion	invasion	NN
cord-262786-otxpc46a	226	13	into	into	IN
cord-262786-otxpc46a	226	14	the	the	DT
cord-262786-otxpc46a	226	15	CNS	CNS	NNP
cord-262786-otxpc46a	226	16	,	,	,
cord-262786-otxpc46a	226	17	recent	recent	JJ
cord-262786-otxpc46a	226	18	findings	finding	NNS
cord-262786-otxpc46a	226	19	are	be	VBP
cord-262786-otxpc46a	226	20	in	in	IN
cord-262786-otxpc46a	226	21	favor	favor	NN
cord-262786-otxpc46a	226	22	of	of	IN
cord-262786-otxpc46a	226	23	immune	immune	NN
cord-262786-otxpc46a	226	24	-	-	HYPH
cord-262786-otxpc46a	226	25	mediated	mediate	VBN
cord-262786-otxpc46a	226	26	CNS	CNS	NNP
cord-262786-otxpc46a	226	27	involvement	involvement	NN
cord-262786-otxpc46a	226	28	[	[	-LRB-
cord-262786-otxpc46a	226	29	31	31	CD
cord-262786-otxpc46a	226	30	]	]	-RRB-
cord-262786-otxpc46a	226	31	.	.	.
cord-262786-otxpc46a	227	1	SARS	SARS	NNP
cord-262786-otxpc46a	227	2	-	-	HYPH
cord-262786-otxpc46a	227	3	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	227	4	genome	genome	NN
cord-262786-otxpc46a	227	5	sequences	sequence	NNS
cord-262786-otxpc46a	227	6	are	be	VBP
cord-262786-otxpc46a	227	7	frequently	frequently	RB
cord-262786-otxpc46a	227	8	undetectable	undetectable	JJ
cord-262786-otxpc46a	227	9	in	in	IN
cord-262786-otxpc46a	227	10	the	the	DT
cord-262786-otxpc46a	227	11	CSF	CSF	NNP
cord-262786-otxpc46a	227	12	[	[	-LRB-
cord-262786-otxpc46a	227	13	93	93	CD
cord-262786-otxpc46a	227	14	]	]	-RRB-
cord-262786-otxpc46a	227	15	.	.	.
cord-262786-otxpc46a	228	1	Also	also	RB
cord-262786-otxpc46a	228	2	,	,	,
cord-262786-otxpc46a	228	3	recent	recent	JJ
cord-262786-otxpc46a	228	4	studies	study	NNS
cord-262786-otxpc46a	228	5	suggest	suggest	VBP
cord-262786-otxpc46a	228	6	that	that	IN
cord-262786-otxpc46a	228	7	blood	blood	NN
cord-262786-otxpc46a	228	8	-	-	HYPH
cord-262786-otxpc46a	228	9	brain	brain	NN
cord-262786-otxpc46a	228	10	barrier	barrier	NN
cord-262786-otxpc46a	228	11	integrity	integrity	NN
cord-262786-otxpc46a	228	12	is	be	VBZ
cord-262786-otxpc46a	228	13	disrupted	disrupt	VBN
cord-262786-otxpc46a	228	14	,	,	,
cord-262786-otxpc46a	228	15	and	and	CC
cord-262786-otxpc46a	228	16	lymphocytic	lymphocytic	JJ
cord-262786-otxpc46a	228	17	pleocytosis	pleocytosis	NNP
cord-262786-otxpc46a	228	18	and	and	CC
cord-262786-otxpc46a	228	19	WBC	WBC	NNP
cord-262786-otxpc46a	228	20	infiltration	infiltration	NN
cord-262786-otxpc46a	228	21	into	into	IN
cord-262786-otxpc46a	228	22	the	the	DT
cord-262786-otxpc46a	228	23	CNS	CNS	NNP
cord-262786-otxpc46a	228	24	occur	occur	VBP
cord-262786-otxpc46a	228	25	in	in	IN
cord-262786-otxpc46a	228	26	these	these	DT
cord-262786-otxpc46a	228	27	patients	patient	NNS
cord-262786-otxpc46a	228	28	[	[	-LRB-
cord-262786-otxpc46a	228	29	93	93	CD
cord-262786-otxpc46a	228	30	]	]	-RRB-
cord-262786-otxpc46a	228	31	.	.	.
cord-262786-otxpc46a	229	1	Interestingly	interestingly	RB
cord-262786-otxpc46a	229	2	,	,	,
cord-262786-otxpc46a	229	3	the	the	DT
cord-262786-otxpc46a	229	4	presence	presence	NN
cord-262786-otxpc46a	229	5	of	of	IN
cord-262786-otxpc46a	229	6	auto	auto	NN
cord-262786-otxpc46a	229	7	-	-	HYPH
cord-262786-otxpc46a	229	8	antibodies	antibody	NNS
cord-262786-otxpc46a	229	9	against	against	IN
cord-262786-otxpc46a	229	10	gangliosides	ganglioside	NNS
cord-262786-otxpc46a	229	11	in	in	IN
cord-262786-otxpc46a	229	12	SARS	SARS	NNP
cord-262786-otxpc46a	229	13	-	-	HYPH
cord-262786-otxpc46a	229	14	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	229	15	patients	patient	NNS
cord-262786-otxpc46a	229	16	suggests	suggest	VBZ
cord-262786-otxpc46a	229	17	that	that	IN
cord-262786-otxpc46a	229	18	an	an	DT
cord-262786-otxpc46a	229	19	autoimmune	autoimmune	JJ
cord-262786-otxpc46a	229	20	phenomenon	phenomenon	NN
cord-262786-otxpc46a	229	21	mediated	mediate	VBN
cord-262786-otxpc46a	229	22	by	by	IN
cord-262786-otxpc46a	229	23	the	the	DT
cord-262786-otxpc46a	229	24	virus	virus	NN
cord-262786-otxpc46a	229	25	might	may	MD
cord-262786-otxpc46a	229	26	underlie	underlie	VB
cord-262786-otxpc46a	229	27	the	the	DT
cord-262786-otxpc46a	229	28	neurologic	neurologic	JJ
cord-262786-otxpc46a	229	29	symptoms	symptom	NNS
cord-262786-otxpc46a	229	30	[	[	-LRB-
cord-262786-otxpc46a	229	31	93	93	CD
cord-262786-otxpc46a	229	32	]	]	-RRB-
cord-262786-otxpc46a	229	33	.	.	.
cord-262786-otxpc46a	230	1	As	as	IN
cord-262786-otxpc46a	230	2	a	a	DT
cord-262786-otxpc46a	230	3	result	result	NN
cord-262786-otxpc46a	230	4	,	,	,
cord-262786-otxpc46a	230	5	we	-PRON-	PRP
cord-262786-otxpc46a	230	6	propose	propose	VBP
cord-262786-otxpc46a	230	7	that	that	IN
cord-262786-otxpc46a	230	8	the	the	DT
cord-262786-otxpc46a	230	9	aberrant	aberrant	JJ
cord-262786-otxpc46a	230	10	immune	immune	JJ
cord-262786-otxpc46a	230	11	response	response	NN
cord-262786-otxpc46a	230	12	mediated	mediate	VBN
cord-262786-otxpc46a	230	13	by	by	IN
cord-262786-otxpc46a	230	14	SARS	SARS	NNP
cord-262786-otxpc46a	230	15	-	-	HYPH
cord-262786-otxpc46a	230	16	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	230	17	is	be	VBZ
cord-262786-otxpc46a	230	18	responsible	responsible	JJ
cord-262786-otxpc46a	230	19	for	for	IN
cord-262786-otxpc46a	230	20	the	the	DT
cord-262786-otxpc46a	230	21	majority	majority	NN
cord-262786-otxpc46a	230	22	of	of	IN
cord-262786-otxpc46a	230	23	acute	acute	JJ
cord-262786-otxpc46a	230	24	or	or	CC
cord-262786-otxpc46a	230	25	chronic	chronic	JJ
cord-262786-otxpc46a	230	26	neurological	neurological	JJ
cord-262786-otxpc46a	230	27	manifestations	manifestation	NNS
cord-262786-otxpc46a	230	28	.	.	.
cord-262786-otxpc46a	231	1	In	in	IN
cord-262786-otxpc46a	231	2	fact	fact	NN
cord-262786-otxpc46a	231	3	,	,	,
cord-262786-otxpc46a	231	4	SARS	SARS	NNP
cord-262786-otxpc46a	231	5	-	-	HYPH
cord-262786-otxpc46a	231	6	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	231	7	infection	infection	NN
cord-262786-otxpc46a	231	8	increases	increase	VBZ
cord-262786-otxpc46a	231	9	the	the	DT
cord-262786-otxpc46a	231	10	risk	risk	NN
cord-262786-otxpc46a	231	11	of	of	IN
cord-262786-otxpc46a	231	12	Alzheimer	Alzheimer	NNP
cord-262786-otxpc46a	231	13	's	's	POS
cord-262786-otxpc46a	231	14	disease	disease	NN
cord-262786-otxpc46a	231	15	,	,	,
cord-262786-otxpc46a	231	16	Parkinson	Parkinson	NNP
cord-262786-otxpc46a	231	17	's	's	POS
cord-262786-otxpc46a	231	18	disease	disease	NN
cord-262786-otxpc46a	231	19	,	,	,
cord-262786-otxpc46a	231	20	stroke	stroke	NN
cord-262786-otxpc46a	231	21	,	,	,
cord-262786-otxpc46a	231	22	multiple	multiple	JJ
cord-262786-otxpc46a	231	23	sclerosis	sclerosis	NN
cord-262786-otxpc46a	231	24	,	,	,
cord-262786-otxpc46a	231	25	Guillain	Guillain	NNP
cord-262786-otxpc46a	231	26	-	-	HYPH
cord-262786-otxpc46a	231	27	Barre	Barre	NNP
cord-262786-otxpc46a	231	28	syndrome	syndrome	NN
cord-262786-otxpc46a	231	29	,	,	,
cord-262786-otxpc46a	231	30	seizure	seizure	NN
cord-262786-otxpc46a	231	31	,	,	,
cord-262786-otxpc46a	231	32	encephalopathy	encephalopathy	NN
cord-262786-otxpc46a	231	33	,	,	,
cord-262786-otxpc46a	231	34	and	and	CC
cord-262786-otxpc46a	231	35	brainstem	brainstem	NN
cord-262786-otxpc46a	231	36	involvement	involvement	NN
cord-262786-otxpc46a	231	37	through	through	IN
cord-262786-otxpc46a	231	38	different	different	JJ
cord-262786-otxpc46a	231	39	immune	immune	JJ
cord-262786-otxpc46a	231	40	pathways	pathway	NNS
cord-262786-otxpc46a	231	41	including	include	VBG
cord-262786-otxpc46a	231	42	Fig	Fig	NNP
cord-262786-otxpc46a	231	43	.	.	.
cord-262786-otxpc46a	232	1	3	3	LS
cord-262786-otxpc46a	233	1	The	the	DT
cord-262786-otxpc46a	233	2	pathomechanisms	pathomechanism	NNS
cord-262786-otxpc46a	233	3	of	of	IN
cord-262786-otxpc46a	233	4	immune	immune	NN
cord-262786-otxpc46a	233	5	-	-	HYPH
cord-262786-otxpc46a	233	6	mediated	mediate	VBN
cord-262786-otxpc46a	233	7	CNS	CNS	NNP
cord-262786-otxpc46a	233	8	involvement	involvement	NN
cord-262786-otxpc46a	233	9	in	in	IN
cord-262786-otxpc46a	233	10	SARS	SARS	NNP
cord-262786-otxpc46a	233	11	-	-	HYPH
cord-262786-otxpc46a	233	12	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	233	13	infection	infection	NN
cord-262786-otxpc46a	233	14	.	.	.
cord-262786-otxpc46a	234	1	SARS	SARS	NNP
cord-262786-otxpc46a	234	2	-	-	HYPH
cord-262786-otxpc46a	234	3	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	234	4	induces	induce	VBZ
cord-262786-otxpc46a	234	5	neurodegeneration	neurodegeneration	NN
cord-262786-otxpc46a	234	6	through	through	IN
cord-262786-otxpc46a	234	7	cytokine	cytokine	NN
cord-262786-otxpc46a	234	8	storm	storm	NN
cord-262786-otxpc46a	234	9	,	,	,
cord-262786-otxpc46a	234	10	autoimmunity	autoimmunity	NN
cord-262786-otxpc46a	234	11	,	,	,
cord-262786-otxpc46a	234	12	microglial	microglial	NNP
cord-262786-otxpc46a	234	13	and	and	CC
cord-262786-otxpc46a	234	14	inflammasome	inflammasome	NNP
cord-262786-otxpc46a	234	15	activation	activation	NN
cord-262786-otxpc46a	234	16	,	,	,
cord-262786-otxpc46a	234	17	and	and	CC
cord-262786-otxpc46a	234	18	gut	gut	NN
cord-262786-otxpc46a	234	19	microbiome	microbiome	NN
cord-262786-otxpc46a	234	20	modulation	modulation	NN
cord-262786-otxpc46a	234	21	.	.	.
cord-262786-otxpc46a	235	1	These	these	DT
cord-262786-otxpc46a	235	2	pathways	pathway	NNS
cord-262786-otxpc46a	235	3	lead	lead	VBP
cord-262786-otxpc46a	235	4	to	to	IN
cord-262786-otxpc46a	235	5	development	development	NN
cord-262786-otxpc46a	235	6	of	of	IN
cord-262786-otxpc46a	235	7	Alzheimer	Alzheimer	NNP
cord-262786-otxpc46a	235	8	's	's	POS
cord-262786-otxpc46a	235	9	disease	disease	NN
cord-262786-otxpc46a	235	10	in	in	IN
cord-262786-otxpc46a	235	11	susceptible	susceptible	JJ
cord-262786-otxpc46a	235	12	individuals	individual	NNS
cord-262786-otxpc46a	235	13	and	and	CC
cord-262786-otxpc46a	235	14	worsen	worsen	VB
cord-262786-otxpc46a	235	15	the	the	DT
cord-262786-otxpc46a	235	16	severity	severity	NN
cord-262786-otxpc46a	235	17	of	of	IN
cord-262786-otxpc46a	235	18	Parkinson	Parkinson	NNP
cord-262786-otxpc46a	235	19	's	's	POS
cord-262786-otxpc46a	235	20	disease	disease	NN
cord-262786-otxpc46a	235	21	in	in	IN
cord-262786-otxpc46a	235	22	affected	affected	JJ
cord-262786-otxpc46a	235	23	patients	patient	NNS
cord-262786-otxpc46a	235	24	.	.	.
cord-262786-otxpc46a	236	1	Inflammatorymediated	inflammatorymediated	JJ
cord-262786-otxpc46a	236	2	vascular	vascular	JJ
cord-262786-otxpc46a	236	3	wall	wall	NN
cord-262786-otxpc46a	236	4	injury	injury	NN
cord-262786-otxpc46a	236	5	,	,	,
cord-262786-otxpc46a	236	6	atrial	atrial	JJ
cord-262786-otxpc46a	236	7	fibrillation	fibrillation	NN
cord-262786-otxpc46a	236	8	,	,	,
cord-262786-otxpc46a	236	9	carotid	carotid	JJ
cord-262786-otxpc46a	236	10	plaque	plaque	NN
cord-262786-otxpc46a	236	11	rupture	rupture	NN
cord-262786-otxpc46a	236	12	,	,	,
cord-262786-otxpc46a	236	13	and	and	CC
cord-262786-otxpc46a	236	14	upregulation	upregulation	NN
cord-262786-otxpc46a	236	15	of	of	IN
cord-262786-otxpc46a	236	16	pro	pro	JJ
cord-262786-otxpc46a	236	17	-	-	JJ
cord-262786-otxpc46a	236	18	coagulative	coagulative	JJ
cord-262786-otxpc46a	236	19	factors	factor	NNS
cord-262786-otxpc46a	236	20	may	may	MD
cord-262786-otxpc46a	236	21	increase	increase	VB
cord-262786-otxpc46a	236	22	the	the	DT
cord-262786-otxpc46a	236	23	risk	risk	NN
cord-262786-otxpc46a	236	24	of	of	IN
cord-262786-otxpc46a	236	25	stroke	stroke	NN
cord-262786-otxpc46a	236	26	in	in	IN
cord-262786-otxpc46a	236	27	these	these	DT
cord-262786-otxpc46a	236	28	patients	patient	NNS
cord-262786-otxpc46a	236	29	.	.	.
cord-262786-otxpc46a	237	1	Cytokine	cytokine	NN
cord-262786-otxpc46a	237	2	storm	storm	NN
cord-262786-otxpc46a	237	3	and	and	CC
cord-262786-otxpc46a	237	4	autoimmunity	autoimmunity	NN
cord-262786-otxpc46a	237	5	induced	induce	VBN
cord-262786-otxpc46a	237	6	by	by	IN
cord-262786-otxpc46a	237	7	cross	cross	NN
cord-262786-otxpc46a	237	8	-	-	NN
cord-262786-otxpc46a	237	9	reactivity	reactivity	NN
cord-262786-otxpc46a	237	10	between	between	IN
cord-262786-otxpc46a	237	11	viral	viral	JJ
cord-262786-otxpc46a	237	12	particles	particle	NNS
cord-262786-otxpc46a	237	13	and	and	CC
cord-262786-otxpc46a	237	14	CNS	CNS	NNP
cord-262786-otxpc46a	237	15	components	component	NNS
cord-262786-otxpc46a	237	16	may	may	MD
cord-262786-otxpc46a	237	17	contribute	contribute	VB
cord-262786-otxpc46a	237	18	to	to	IN
cord-262786-otxpc46a	237	19	the	the	DT
cord-262786-otxpc46a	237	20	development	development	NN
cord-262786-otxpc46a	237	21	of	of	IN
cord-262786-otxpc46a	237	22	autoimmune	autoimmune	JJ
cord-262786-otxpc46a	237	23	disorders	disorder	NNS
cord-262786-otxpc46a	237	24	of	of	IN
cord-262786-otxpc46a	237	25	CNS	CNS	NNP
cord-262786-otxpc46a	237	26	,	,	,
cord-262786-otxpc46a	237	27	like	like	IN
cord-262786-otxpc46a	237	28	Guillain	Guillain	NNP
cord-262786-otxpc46a	237	29	-	-	HYPH
cord-262786-otxpc46a	237	30	Barre	Barre	NNP
cord-262786-otxpc46a	237	31	syndrome	syndrome	NN
cord-262786-otxpc46a	237	32	.	.	.
cord-262786-otxpc46a	238	1	Also	also	RB
cord-262786-otxpc46a	238	2	,	,	,
cord-262786-otxpc46a	238	3	the	the	DT
cord-262786-otxpc46a	238	4	aforementioned	aforementioned	JJ
cord-262786-otxpc46a	238	5	mechanisms	mechanism	NNS
cord-262786-otxpc46a	238	6	exacerbate	exacerbate	VBP
cord-262786-otxpc46a	238	7	symptoms	symptom	NNS
cord-262786-otxpc46a	238	8	in	in	IN
cord-262786-otxpc46a	238	9	multiple	multiple	JJ
cord-262786-otxpc46a	238	10	sclerosis	sclerosis	NN
cord-262786-otxpc46a	238	11	patients	patient	NNS
cord-262786-otxpc46a	238	12	.	.	.
cord-262786-otxpc46a	239	1	Cytokine	cytokine	NN
cord-262786-otxpc46a	239	2	storm	storm	NN
cord-262786-otxpc46a	239	3	induces	induce	VBZ
cord-262786-otxpc46a	239	4	microglial	microglial	JJ
cord-262786-otxpc46a	239	5	activation	activation	NN
cord-262786-otxpc46a	239	6	and	and	CC
cord-262786-otxpc46a	239	7	WBC	WBC	NNP
cord-262786-otxpc46a	239	8	infiltration	infiltration	NN
cord-262786-otxpc46a	239	9	into	into	IN
cord-262786-otxpc46a	239	10	the	the	DT
cord-262786-otxpc46a	239	11	CNS	CNS	NNP
cord-262786-otxpc46a	239	12	and	and	CC
cord-262786-otxpc46a	239	13	,	,	,
cord-262786-otxpc46a	239	14	thus	thus	RB
cord-262786-otxpc46a	239	15	,	,	,
cord-262786-otxpc46a	239	16	precipitates	precipitate	VBZ
cord-262786-otxpc46a	239	17	seizure	seizure	NN
cord-262786-otxpc46a	239	18	and	and	CC
cord-262786-otxpc46a	239	19	encephalopathy	encephalopathy	NN
cord-262786-otxpc46a	239	20	.	.	.
cord-262786-otxpc46a	240	1	CNS	CNS	NNP
cord-262786-otxpc46a	240	2	central	central	JJ
cord-262786-otxpc46a	240	3	nervous	nervous	JJ
cord-262786-otxpc46a	240	4	system	system	NN
cord-262786-otxpc46a	240	5	,	,	,
cord-262786-otxpc46a	240	6	WBC	WBC	NNP
cord-262786-otxpc46a	240	7	white	white	JJ
cord-262786-otxpc46a	240	8	blood	blood	NN
cord-262786-otxpc46a	240	9	cell	cell	NN
cord-262786-otxpc46a	240	10	.	.	.
cord-262786-otxpc46a	241	1	Adopted	adopt	VBN
cord-262786-otxpc46a	241	2	from	from	IN
cord-262786-otxpc46a	241	3	https://www.dpz.eu/de/infothek/wissen/	https://www.dpz.eu/de/infothek/wissen/	NNP
cord-262786-otxpc46a	241	4	coronaviren.html	coronaviren.html	NNP
cord-262786-otxpc46a	241	5	,	,	,
cord-262786-otxpc46a	241	6	by	by	IN
cord-262786-otxpc46a	241	7	Markus	Markus	NNP
cord-262786-otxpc46a	241	8	Hoffmann	Hoffmann	NNP
cord-262786-otxpc46a	241	9	.	.	.
cord-262786-otxpc46a	242	1	Adopted	adopt	VBN
cord-262786-otxpc46a	242	2	with	with	IN
cord-262786-otxpc46a	242	3	permission	permission	NN
cord-262786-otxpc46a	242	4	cytokine	cytokine	NN
cord-262786-otxpc46a	242	5	storm	storm	NN
cord-262786-otxpc46a	242	6	,	,	,
cord-262786-otxpc46a	242	7	autoimmunity	autoimmunity	NN
cord-262786-otxpc46a	242	8	,	,	,
cord-262786-otxpc46a	242	9	microglial	microglial	NNP
cord-262786-otxpc46a	242	10	and	and	CC
cord-262786-otxpc46a	242	11	inflammasome	inflammasome	NNP
cord-262786-otxpc46a	242	12	activation	activation	NN
cord-262786-otxpc46a	242	13	,	,	,
cord-262786-otxpc46a	242	14	gut	gut	NN
cord-262786-otxpc46a	242	15	microbiome	microbiome	NN
cord-262786-otxpc46a	242	16	modulation	modulation	NN
cord-262786-otxpc46a	242	17	,	,	,
cord-262786-otxpc46a	242	18	WBC	WBC	NNP
cord-262786-otxpc46a	242	19	infiltration	infiltration	NN
cord-262786-otxpc46a	242	20	into	into	IN
cord-262786-otxpc46a	242	21	the	the	DT
cord-262786-otxpc46a	242	22	CNS	CNS	NNP
cord-262786-otxpc46a	242	23	,	,	,
cord-262786-otxpc46a	242	24	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	242	25	-	-	HYPH
cord-262786-otxpc46a	242	26	mediated	mediate	VBN
cord-262786-otxpc46a	242	27	vascular	vascular	JJ
cord-262786-otxpc46a	242	28	wall	wall	NN
cord-262786-otxpc46a	242	29	injury	injury	NN
cord-262786-otxpc46a	242	30	,	,	,
cord-262786-otxpc46a	242	31	and	and	CC
cord-262786-otxpc46a	242	32	upregulation	upregulation	NN
cord-262786-otxpc46a	242	33	of	of	IN
cord-262786-otxpc46a	242	34	pro	pro	JJ
cord-262786-otxpc46a	242	35	-	-	JJ
cord-262786-otxpc46a	242	36	coagulative	coagulative	JJ
cord-262786-otxpc46a	242	37	factors	factor	NNS
cord-262786-otxpc46a	242	38	(	(	-LRB-
cord-262786-otxpc46a	242	39	Fig	Fig	NNP
cord-262786-otxpc46a	242	40	.	.	.
cord-262786-otxpc46a	242	41	3	3	CD
cord-262786-otxpc46a	242	42	)	)	-RRB-
cord-262786-otxpc46a	242	43	.	.	.
cord-262786-otxpc46a	243	1	Precise	precise	JJ
cord-262786-otxpc46a	243	2	investigation	investigation	NN
cord-262786-otxpc46a	243	3	and	and	CC
cord-262786-otxpc46a	243	4	follow	follow	NN
cord-262786-otxpc46a	243	5	-	-	HYPH
cord-262786-otxpc46a	243	6	up	up	NN
cord-262786-otxpc46a	243	7	of	of	IN
cord-262786-otxpc46a	243	8	SARS	SARS	NNP
cord-262786-otxpc46a	243	9	-	-	HYPH
cord-262786-otxpc46a	243	10	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	243	11	patients	patient	NNS
cord-262786-otxpc46a	243	12	is	be	VBZ
cord-262786-otxpc46a	243	13	warranted	warrant	VBN
cord-262786-otxpc46a	243	14	in	in	IN
cord-262786-otxpc46a	243	15	this	this	DT
cord-262786-otxpc46a	243	16	issue	issue	NN
cord-262786-otxpc46a	243	17	,	,	,
cord-262786-otxpc46a	243	18	as	as	IN
cord-262786-otxpc46a	243	19	the	the	DT
cord-262786-otxpc46a	243	20	delayed	delay	VBN
cord-262786-otxpc46a	243	21	presentation	presentation	NN
cord-262786-otxpc46a	243	22	of	of	IN
cord-262786-otxpc46a	243	23	these	these	DT
cord-262786-otxpc46a	243	24	complications	complication	NNS
cord-262786-otxpc46a	243	25	may	may	MD
cord-262786-otxpc46a	243	26	lead	lead	VB
cord-262786-otxpc46a	243	27	to	to	IN
cord-262786-otxpc46a	243	28	underdiagnosis	underdiagnosis	NN
cord-262786-otxpc46a	243	29	.	.	.
cord-262786-otxpc46a	244	1	Immunomodulatory	immunomodulatory	JJ
cord-262786-otxpc46a	244	2	drugs	drug	NNS
cord-262786-otxpc46a	244	3	such	such	JJ
cord-262786-otxpc46a	244	4	as	as	IN
cord-262786-otxpc46a	244	5	cytokine	cytokine	NN
cord-262786-otxpc46a	244	6	-	-	HYPH
cord-262786-otxpc46a	244	7	blocking	block	VBG
cord-262786-otxpc46a	244	8	therapies	therapy	NNS
cord-262786-otxpc46a	244	9	(	(	-LRB-
cord-262786-otxpc46a	244	10	e.g.	e.g.	RB
cord-262786-otxpc46a	244	11	,	,	,
cord-262786-otxpc46a	244	12	IL-6R	IL-6R	NNP
cord-262786-otxpc46a	244	13	monoclonal	monoclonal	JJ
cord-262786-otxpc46a	244	14	antibodies	antibody	NNS
cord-262786-otxpc46a	244	15	,	,	,
cord-262786-otxpc46a	245	1	TNF	TNF	NNP
cord-262786-otxpc46a	245	2	-	-	HYPH
cord-262786-otxpc46a	245	3	α	α	NNP
cord-262786-otxpc46a	245	4	inhibitors	inhibitor	NNS
cord-262786-otxpc46a	245	5	,	,	,
cord-262786-otxpc46a	245	6	IL-1β	il-1β	DT
cord-262786-otxpc46a	245	7	antagonists	antagonist	NNS
cord-262786-otxpc46a	245	8	)	)	-RRB-
cord-262786-otxpc46a	245	9	,	,	,
cord-262786-otxpc46a	245	10	antibodies	antibody	NNS
cord-262786-otxpc46a	245	11	against	against	IN
cord-262786-otxpc46a	245	12	viral	viral	JJ
cord-262786-otxpc46a	245	13	spike	spike	NN
cord-262786-otxpc46a	245	14	proteins	protein	NNS
cord-262786-otxpc46a	245	15	and	and	CC
cord-262786-otxpc46a	245	16	viral	viral	JJ
cord-262786-otxpc46a	245	17	binding	bind	VBG
cord-262786-otxpc46a	245	18	receptors	receptor	NNS
cord-262786-otxpc46a	245	19	(	(	-LRB-
cord-262786-otxpc46a	245	20	ACE-2	ACE-2	NNP
cord-262786-otxpc46a	245	21	)	)	-RRB-
cord-262786-otxpc46a	245	22	,	,	,
cord-262786-otxpc46a	245	23	anti	anti	JJ
cord-262786-otxpc46a	245	24	-	-	JJ
cord-262786-otxpc46a	245	25	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	245	26	drugs	drug	NNS
cord-262786-otxpc46a	245	27	like	like	IN
cord-262786-otxpc46a	245	28	nonsteroidal	nonsteroidal	JJ
cord-262786-otxpc46a	245	29	antiinflammatory	antiinflammatory	JJ
cord-262786-otxpc46a	245	30	drug	drug	NN
cord-262786-otxpc46a	245	31	(	(	-LRB-
cord-262786-otxpc46a	245	32	NSAID	NSAID	NNP
cord-262786-otxpc46a	245	33	)	)	-RRB-
cord-262786-otxpc46a	245	34	,	,	,
cord-262786-otxpc46a	245	35	and	and	CC
cord-262786-otxpc46a	245	36	prophylactic	prophylactic	JJ
cord-262786-otxpc46a	245	37	antibodies	antibody	NNS
cord-262786-otxpc46a	245	38	are	be	VBP
cord-262786-otxpc46a	245	39	under	under	IN
cord-262786-otxpc46a	245	40	investigation	investigation	NN
cord-262786-otxpc46a	245	41	in	in	IN
cord-262786-otxpc46a	245	42	the	the	DT
cord-262786-otxpc46a	245	43	prevention	prevention	NN
cord-262786-otxpc46a	245	44	and	and	CC
cord-262786-otxpc46a	245	45	treatment	treatment	NN
cord-262786-otxpc46a	245	46	of	of	IN
cord-262786-otxpc46a	245	47	SARS	SARS	NNP
cord-262786-otxpc46a	245	48	-	-	HYPH
cord-262786-otxpc46a	245	49	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	245	50	[	[	-LRB-
cord-262786-otxpc46a	245	51	94	94	CD
cord-262786-otxpc46a	245	52	,	,	,
cord-262786-otxpc46a	245	53	95	95	CD
cord-262786-otxpc46a	245	54	]	]	-RRB-
cord-262786-otxpc46a	245	55	.	.	.
cord-262786-otxpc46a	246	1	However	however	RB
cord-262786-otxpc46a	246	2	,	,	,
cord-262786-otxpc46a	246	3	the	the	DT
cord-262786-otxpc46a	246	4	efficiency	efficiency	NN
cord-262786-otxpc46a	246	5	of	of	IN
cord-262786-otxpc46a	246	6	these	these	DT
cord-262786-otxpc46a	246	7	drugs	drug	NNS
cord-262786-otxpc46a	246	8	to	to	TO
cord-262786-otxpc46a	246	9	decline	decline	VB
cord-262786-otxpc46a	246	10	the	the	DT
cord-262786-otxpc46a	246	11	burden	burden	NN
cord-262786-otxpc46a	246	12	of	of	IN
cord-262786-otxpc46a	246	13	short	short	JJ
cord-262786-otxpc46a	246	14	-	-	HYPH
cord-262786-otxpc46a	246	15	term	term	NN
cord-262786-otxpc46a	246	16	and	and	CC
cord-262786-otxpc46a	246	17	long	long	JJ
cord-262786-otxpc46a	246	18	-	-	HYPH
cord-262786-otxpc46a	246	19	term	term	NN
cord-262786-otxpc46a	246	20	neurological	neurological	JJ
cord-262786-otxpc46a	246	21	manifestations	manifestation	NNS
cord-262786-otxpc46a	246	22	of	of	IN
cord-262786-otxpc46a	246	23	SARS	SARS	NNP
cord-262786-otxpc46a	246	24	-	-	HYPH
cord-262786-otxpc46a	246	25	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	246	26	is	be	VBZ
cord-262786-otxpc46a	246	27	yet	yet	RB
cord-262786-otxpc46a	246	28	to	to	TO
cord-262786-otxpc46a	246	29	be	be	VB
cord-262786-otxpc46a	246	30	investigated	investigate	VBN
cord-262786-otxpc46a	246	31	.	.	.
cord-262786-otxpc46a	247	1	A	a	DT
cord-262786-otxpc46a	247	2	systematic	systematic	JJ
cord-262786-otxpc46a	247	3	review	review	NN
cord-262786-otxpc46a	247	4	of	of	IN
cord-262786-otxpc46a	247	5	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	247	6	epidemiology	epidemiology	NN
cord-262786-otxpc46a	247	7	based	base	VBN
cord-262786-otxpc46a	247	8	on	on	IN
cord-262786-otxpc46a	247	9	current	current	JJ
cord-262786-otxpc46a	247	10	evidence	evidence	NN
cord-262786-otxpc46a	247	11	Di	Di	NNP
cord-262786-otxpc46a	247	12	Napoli	Napoli	NNP
cord-262786-otxpc46a	247	13	R	r	NN
cord-262786-otxpc46a	247	14	(	(	-LRB-
cord-262786-otxpc46a	247	15	2020	2020	CD
cord-262786-otxpc46a	247	16	)	)	-RRB-
cord-262786-otxpc46a	247	17	Features	feature	NNS
cord-262786-otxpc46a	247	18	,	,	,
cord-262786-otxpc46a	247	19	evaluation	evaluation	NN
cord-262786-otxpc46a	247	20	and	and	CC
cord-262786-otxpc46a	247	21	treatment	treatment	NN
cord-262786-otxpc46a	247	22	coronavirus	coronavirus	NN
cord-262786-otxpc46a	247	23	(	(	-LRB-
cord-262786-otxpc46a	247	24	COVID-19	covid-19	VB
cord-262786-otxpc46a	247	25	)	)	-RRB-
cord-262786-otxpc46a	247	26	Neurologic	neurologic	JJ
cord-262786-otxpc46a	247	27	manifestations	manifestation	NNS
cord-262786-otxpc46a	247	28	of	of	IN
cord-262786-otxpc46a	247	29	hospitalized	hospitalize	VBN
cord-262786-otxpc46a	247	30	patients	patient	NNS
cord-262786-otxpc46a	247	31	with	with	IN
cord-262786-otxpc46a	247	32	coronavirus	coronavirus	NN
cord-262786-otxpc46a	247	33	disease	disease	NN
cord-262786-otxpc46a	247	34	2019	2019	CD
cord-262786-otxpc46a	247	35	in	in	IN
cord-262786-otxpc46a	247	36	Wuhan	Wuhan	NNP
cord-262786-otxpc46a	247	37	,	,	,
cord-262786-otxpc46a	247	38	China	China	NNP
cord-262786-otxpc46a	247	39	Neurologic	Neurologic	NNP
cord-262786-otxpc46a	247	40	features	feature	VBZ
cord-262786-otxpc46a	247	41	in	in	IN
cord-262786-otxpc46a	247	42	severe	severe	JJ
cord-262786-otxpc46a	247	43	SARS	SARS	NNP
cord-262786-otxpc46a	247	44	-	-	HYPH
cord-262786-otxpc46a	247	45	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	247	46	infection	infection	NN
cord-262786-otxpc46a	247	47	Brain	Brain	NNP
cord-262786-otxpc46a	247	48	MRI	MRI	NNP
cord-262786-otxpc46a	247	49	findings	finding	NNS
cord-262786-otxpc46a	247	50	in	in	IN
cord-262786-otxpc46a	247	51	patients	patient	NNS
cord-262786-otxpc46a	247	52	in	in	IN
cord-262786-otxpc46a	247	53	the	the	DT
cord-262786-otxpc46a	247	54	intensive	intensive	JJ
cord-262786-otxpc46a	247	55	care	care	NN
cord-262786-otxpc46a	247	56	unit	unit	NN
cord-262786-otxpc46a	247	57	with	with	IN
cord-262786-otxpc46a	247	58	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	247	59	infection	infection	NN
cord-262786-otxpc46a	247	60	Brain	Brain	NNP
cord-262786-otxpc46a	247	61	MRI	MRI	NNP
cord-262786-otxpc46a	247	62	findings	finding	NNS
cord-262786-otxpc46a	247	63	in	in	IN
cord-262786-otxpc46a	247	64	severe	severe	JJ
cord-262786-otxpc46a	247	65	COVID-19	covid-19	NN
cord-262786-otxpc46a	247	66	:	:	:
cord-262786-otxpc46a	247	67	a	a	DT
cord-262786-otxpc46a	247	68	retrospective	retrospective	JJ
cord-262786-otxpc46a	247	69	observational	observational	JJ
cord-262786-otxpc46a	247	70	study	study	NN
cord-262786-otxpc46a	247	71	Report	Report	NNP
cord-262786-otxpc46a	247	72	of	of	IN
cord-262786-otxpc46a	247	73	EEG	EEG	NNP
cord-262786-otxpc46a	247	74	finding	finding	NN
cord-262786-otxpc46a	247	75	on	on	IN
cord-262786-otxpc46a	247	76	critically	critically	RB
cord-262786-otxpc46a	247	77	ill	ill	JJ
cord-262786-otxpc46a	247	78	patients	patient	NNS
cord-262786-otxpc46a	247	79	with	with	IN
cord-262786-otxpc46a	247	80	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	247	81	Intact	Intact	NNP
cord-262786-otxpc46a	247	82	brain	brain	NN
cord-262786-otxpc46a	247	83	network	network	NN
cord-262786-otxpc46a	247	84	function	function	NN
cord-262786-otxpc46a	247	85	in	in	IN
cord-262786-otxpc46a	247	86	an	an	DT
cord-262786-otxpc46a	247	87	unresponsive	unresponsive	JJ
cord-262786-otxpc46a	247	88	patient	patient	NN
cord-262786-otxpc46a	247	89	with	with	IN
cord-262786-otxpc46a	247	90	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	247	91	Neurochemical	Neurochemical	NNP
cord-262786-otxpc46a	247	92	evidence	evidence	NN
cord-262786-otxpc46a	247	93	of	of	IN
cord-262786-otxpc46a	247	94	astrocytic	astrocytic	JJ
cord-262786-otxpc46a	247	95	and	and	CC
cord-262786-otxpc46a	247	96	neuronal	neuronal	JJ
cord-262786-otxpc46a	247	97	injury	injury	NN
cord-262786-otxpc46a	248	1	commonly	commonly	RB
cord-262786-otxpc46a	248	2	The	the	DT
cord-262786-otxpc46a	248	3	hypothalamus	hypothalamus	NN
cord-262786-otxpc46a	248	4	as	as	IN
cord-262786-otxpc46a	248	5	a	a	DT
cord-262786-otxpc46a	248	6	hub	hub	NN
cord-262786-otxpc46a	248	7	for	for	IN
cord-262786-otxpc46a	248	8	SARS	SARS	NNP
cord-262786-otxpc46a	248	9	-	-	HYPH
cord-262786-otxpc46a	248	10	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	248	11	brain	brain	NN
cord-262786-otxpc46a	248	12	infection	infection	NN
cord-262786-otxpc46a	248	13	and	and	CC
cord-262786-otxpc46a	248	14	pathogenesis	pathogenesis	NN
cord-262786-otxpc46a	248	15	Cerebrovascular	cerebrovascular	JJ
cord-262786-otxpc46a	248	16	and	and	CC
cord-262786-otxpc46a	248	17	neurological	neurological	JJ
cord-262786-otxpc46a	248	18	dysfunction	dysfunction	NN
cord-262786-otxpc46a	248	19	under	under	IN
cord-262786-otxpc46a	248	20	the	the	DT
cord-262786-otxpc46a	248	21	threat	threat	NN
cord-262786-otxpc46a	248	22	of	of	IN
cord-262786-otxpc46a	248	23	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	248	24	:	:	:
cord-262786-otxpc46a	248	25	is	be	VBZ
cord-262786-otxpc46a	248	26	there	there	EX
cord-262786-otxpc46a	248	27	a	a	DT
cord-262786-otxpc46a	248	28	comorbid	comorbid	JJ
cord-262786-otxpc46a	248	29	role	role	NN
cord-262786-otxpc46a	248	30	for	for	IN
cord-262786-otxpc46a	248	31	smoking	smoking	NN
cord-262786-otxpc46a	248	32	and	and	CC
cord-262786-otxpc46a	248	33	vaping	vaping	NN
cord-262786-otxpc46a	248	34	?	?	.
cord-262786-otxpc46a	249	1	Immediate	immediate	JJ
cord-262786-otxpc46a	249	2	and	and	CC
cord-262786-otxpc46a	249	3	long	long	JJ
cord-262786-otxpc46a	249	4	-	-	HYPH
cord-262786-otxpc46a	249	5	term	term	NN
cord-262786-otxpc46a	249	6	consequences	consequence	NNS
cord-262786-otxpc46a	249	7	of	of	IN
cord-262786-otxpc46a	249	8	COVID-19	covid-19	JJ
cord-262786-otxpc46a	249	9	infections	infection	NNS
cord-262786-otxpc46a	249	10	for	for	IN
cord-262786-otxpc46a	249	11	the	the	DT
cord-262786-otxpc46a	249	12	development	development	NN
cord-262786-otxpc46a	249	13	of	of	IN
cord-262786-otxpc46a	249	14	neurological	neurological	JJ
cord-262786-otxpc46a	249	15	disease	disease	NN
cord-262786-otxpc46a	249	16	Cranial	cranial	JJ
cord-262786-otxpc46a	249	17	neuropathies	neuropathy	NNS
cord-262786-otxpc46a	249	18	and	and	CC
cord-262786-otxpc46a	249	19	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	249	20	:	:	:
cord-262786-otxpc46a	249	21	neurotropism	neurotropism	NN
cord-262786-otxpc46a	249	22	and	and	CC
cord-262786-otxpc46a	249	23	autoimmunity	autoimmunity	IN
cord-262786-otxpc46a	249	24	Large	large	JJ
cord-262786-otxpc46a	249	25	artery	artery	JJ
cord-262786-otxpc46a	249	26	ischaemic	ischaemic	JJ
cord-262786-otxpc46a	249	27	stroke	stroke	NN
cord-262786-otxpc46a	249	28	in	in	IN
cord-262786-otxpc46a	249	29	severe	severe	JJ
cord-262786-otxpc46a	249	30	acute	acute	JJ
cord-262786-otxpc46a	249	31	respiratory	respiratory	JJ
cord-262786-otxpc46a	249	32	syndrome	syndrome	NN
cord-262786-otxpc46a	249	33	(	(	-LRB-
cord-262786-otxpc46a	249	34	SARS	SARS	NNP
cord-262786-otxpc46a	249	35	)	)	-RRB-
cord-262786-otxpc46a	249	36	Is	be	VBZ
cord-262786-otxpc46a	249	37	the	the	DT
cord-262786-otxpc46a	249	38	collapse	collapse	NN
cord-262786-otxpc46a	249	39	of	of	IN
cord-262786-otxpc46a	249	40	the	the	DT
cord-262786-otxpc46a	249	41	respiratory	respiratory	JJ
cord-262786-otxpc46a	249	42	center	center	NN
cord-262786-otxpc46a	249	43	in	in	IN
cord-262786-otxpc46a	249	44	the	the	DT
cord-262786-otxpc46a	249	45	brain	brain	NN
cord-262786-otxpc46a	249	46	responsible	responsible	JJ
cord-262786-otxpc46a	249	47	for	for	IN
cord-262786-otxpc46a	249	48	respiratory	respiratory	JJ
cord-262786-otxpc46a	249	49	breakdown	breakdown	NN
cord-262786-otxpc46a	249	50	in	in	IN
cord-262786-otxpc46a	249	51	COVID-19	covid-19	JJ
cord-262786-otxpc46a	249	52	patients	patient	NNS
cord-262786-otxpc46a	249	53	?	?	.
cord-262786-otxpc46a	250	1	Nervous	nervous	JJ
cord-262786-otxpc46a	250	2	system	system	NN
cord-262786-otxpc46a	250	3	involvement	involvement	NN
cord-262786-otxpc46a	250	4	after	after	IN
cord-262786-otxpc46a	250	5	infection	infection	NN
cord-262786-otxpc46a	250	6	with	with	IN
cord-262786-otxpc46a	250	7	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	250	8	and	and	CC
cord-262786-otxpc46a	250	9	other	other	JJ
cord-262786-otxpc46a	250	10	coronaviruses	coronaviruse	NNS
cord-262786-otxpc46a	251	1	The	the	DT
cord-262786-otxpc46a	251	2	cognitive	cognitive	JJ
cord-262786-otxpc46a	251	3	consequences	consequence	NNS
cord-262786-otxpc46a	251	4	of	of	IN
cord-262786-otxpc46a	251	5	the	the	DT
cord-262786-otxpc46a	251	6	COVID-19	covid-19	JJ
cord-262786-otxpc46a	251	7	epidemic	epidemic	NN
cord-262786-otxpc46a	251	8	:	:	:
cord-262786-otxpc46a	251	9	collateral	collateral	NN
cord-262786-otxpc46a	251	10	damage	damage	NN
cord-262786-otxpc46a	251	11	?	?	.
cord-262786-otxpc46a	252	1	Brain	Brain	NNP
cord-262786-otxpc46a	252	2	Communications	Communications	NNP
cord-262786-otxpc46a	252	3	Angiotensin	Angiotensin	NNP
cord-262786-otxpc46a	252	4	-	-	HYPH
cord-262786-otxpc46a	252	5	converting	convert	VBG
cord-262786-otxpc46a	252	6	enzyme	enzyme	NN
cord-262786-otxpc46a	252	7	2	2	CD
cord-262786-otxpc46a	252	8	in	in	IN
cord-262786-otxpc46a	252	9	the	the	DT
cord-262786-otxpc46a	252	10	brain	brain	NN
cord-262786-otxpc46a	252	11	:	:	:
cord-262786-otxpc46a	252	12	properties	property	NNS
cord-262786-otxpc46a	252	13	and	and	CC
cord-262786-otxpc46a	252	14	future	future	JJ
cord-262786-otxpc46a	252	15	directions	direction	NNS
cord-262786-otxpc46a	253	1	The	the	DT
cord-262786-otxpc46a	253	2	spatial	spatial	JJ
cord-262786-otxpc46a	253	3	and	and	CC
cord-262786-otxpc46a	253	4	cell	cell	NN
cord-262786-otxpc46a	253	5	-	-	HYPH
cord-262786-otxpc46a	253	6	type	type	NN
cord-262786-otxpc46a	253	7	distribution	distribution	NN
cord-262786-otxpc46a	253	8	of	of	IN
cord-262786-otxpc46a	253	9	SARS	SARS	NNP
cord-262786-otxpc46a	253	10	-	-	HYPH
cord-262786-otxpc46a	253	11	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	253	12	receptor	receptor	NN
cord-262786-otxpc46a	253	13	ACE2	ACE2	NNP
cord-262786-otxpc46a	253	14	in	in	IN
cord-262786-otxpc46a	253	15	human	human	NN
cord-262786-otxpc46a	253	16	and	and	CC
cord-262786-otxpc46a	253	17	mouse	mouse	NN
cord-262786-otxpc46a	253	18	brain	brain	NN
cord-262786-otxpc46a	253	19	SARS	SARS	NNP
cord-262786-otxpc46a	253	20	-	-	HYPH
cord-262786-otxpc46a	253	21	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	253	22	cell	cell	NN
cord-262786-otxpc46a	253	23	entry	entry	NN
cord-262786-otxpc46a	253	24	depends	depend	VBZ
cord-262786-otxpc46a	253	25	on	on	IN
cord-262786-otxpc46a	253	26	ACE2	ACE2	NNP
cord-262786-otxpc46a	253	27	and	and	CC
cord-262786-otxpc46a	253	28	TMPRSS2	TMPRSS2	NNP
cord-262786-otxpc46a	253	29	and	and	CC
cord-262786-otxpc46a	253	30	is	be	VBZ
cord-262786-otxpc46a	253	31	blocked	block	VBN
cord-262786-otxpc46a	253	32	by	by	IN
cord-262786-otxpc46a	253	33	a	a	DT
cord-262786-otxpc46a	253	34	clinically	clinically	RB
cord-262786-otxpc46a	253	35	proven	prove	VBN
cord-262786-otxpc46a	253	36	protease	protease	NN
cord-262786-otxpc46a	253	37	inhibitor	inhibitor	NN
cord-262786-otxpc46a	253	38	Toward	toward	IN
cord-262786-otxpc46a	253	39	a	a	DT
cord-262786-otxpc46a	253	40	theory	theory	NN
cord-262786-otxpc46a	253	41	regarding	regard	VBG
cord-262786-otxpc46a	253	42	the	the	DT
cord-262786-otxpc46a	253	43	pathogenesis	pathogenesis	NN
cord-262786-otxpc46a	253	44	of	of	IN
cord-262786-otxpc46a	253	45	the	the	DT
cord-262786-otxpc46a	253	46	systemic	systemic	JJ
cord-262786-otxpc46a	253	47	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	253	48	response	response	NN
cord-262786-otxpc46a	253	49	syndrome	syndrome	NN
cord-262786-otxpc46a	253	50	:	:	:
cord-262786-otxpc46a	253	51	what	what	WP
cord-262786-otxpc46a	253	52	we	-PRON-	PRP
cord-262786-otxpc46a	253	53	do	do	VBP
cord-262786-otxpc46a	253	54	and	and	CC
cord-262786-otxpc46a	253	55	do	do	VBP
cord-262786-otxpc46a	253	56	not	not	RB
cord-262786-otxpc46a	253	57	know	know	VB
cord-262786-otxpc46a	253	58	about	about	IN
cord-262786-otxpc46a	253	59	cytokine	cytokine	NN
cord-262786-otxpc46a	253	60	regulation	regulation	NN
cord-262786-otxpc46a	254	1	Neurological	neurological	JJ
cord-262786-otxpc46a	254	2	involvement	involvement	NN
cord-262786-otxpc46a	254	3	in	in	IN
cord-262786-otxpc46a	254	4	SARS	SARS	NNP
cord-262786-otxpc46a	254	5	-	-	HYPH
cord-262786-otxpc46a	254	6	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	254	7	infection	infection	NN
cord-262786-otxpc46a	254	8	:	:	:
cord-262786-otxpc46a	254	9	a	a	DT
cord-262786-otxpc46a	254	10	clinical	clinical	JJ
cord-262786-otxpc46a	254	11	systematic	systematic	JJ
cord-262786-otxpc46a	254	12	review	review	NN
cord-262786-otxpc46a	254	13	Impact	Impact	NNP
cord-262786-otxpc46a	254	14	of	of	IN
cord-262786-otxpc46a	254	15	SARS	SARS	NNP
cord-262786-otxpc46a	254	16	-	-	HYPH
cord-262786-otxpc46a	254	17	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	254	18	infection	infection	NN
cord-262786-otxpc46a	254	19	on	on	IN
cord-262786-otxpc46a	254	20	neurodegenerative	neurodegenerative	JJ
cord-262786-otxpc46a	254	21	and	and	CC
cord-262786-otxpc46a	254	22	neuropsychiatric	neuropsychiatric	JJ
cord-262786-otxpc46a	254	23	diseases	disease	NNS
cord-262786-otxpc46a	254	24	:	:	:
cord-262786-otxpc46a	254	25	a	a	DT
cord-262786-otxpc46a	254	26	delayed	delay	VBN
cord-262786-otxpc46a	254	27	pandemic	pandemic	NN
cord-262786-otxpc46a	254	28	?	?	.
cord-262786-otxpc46a	255	1	Psychoneuroendocrine	Psychoneuroendocrine	NNP
cord-262786-otxpc46a	255	2	-	-	HYPH
cord-262786-otxpc46a	255	3	immune	immune	JJ
cord-262786-otxpc46a	255	4	interactions	interaction	NNS
cord-262786-otxpc46a	255	5	in	in	IN
cord-262786-otxpc46a	255	6	COVID-19	covid-19	JJ
cord-262786-otxpc46a	255	7	:	:	:
cord-262786-otxpc46a	255	8	potential	potential	JJ
cord-262786-otxpc46a	255	9	impacts	impact	NNS
cord-262786-otxpc46a	255	10	on	on	IN
cord-262786-otxpc46a	255	11	mental	mental	JJ
cord-262786-otxpc46a	255	12	health	health	NN
cord-262786-otxpc46a	255	13	Autoantibodies	Autoantibodies	NNP
cord-262786-otxpc46a	255	14	against	against	IN
cord-262786-otxpc46a	255	15	human	human	JJ
cord-262786-otxpc46a	255	16	epithelial	epithelial	JJ
cord-262786-otxpc46a	255	17	cells	cell	NNS
cord-262786-otxpc46a	255	18	and	and	CC
cord-262786-otxpc46a	255	19	endothelial	endothelial	JJ
cord-262786-otxpc46a	255	20	cells	cell	NNS
cord-262786-otxpc46a	255	21	after	after	IN
cord-262786-otxpc46a	255	22	severe	severe	JJ
cord-262786-otxpc46a	255	23	acute	acute	JJ
cord-262786-otxpc46a	255	24	respiratory	respiratory	JJ
cord-262786-otxpc46a	255	25	syndrome	syndrome	NN
cord-262786-otxpc46a	255	26	(	(	-LRB-
cord-262786-otxpc46a	255	27	SARS)-associated	sars)-associated	CD
cord-262786-otxpc46a	255	28	coronavirus	coronavirus	NN
cord-262786-otxpc46a	255	29	infection	infection	NN
cord-262786-otxpc46a	255	30	Severe	severe	JJ
cord-262786-otxpc46a	255	31	neurologic	neurologic	JJ
cord-262786-otxpc46a	255	32	syndrome	syndrome	NN
cord-262786-otxpc46a	255	33	associated	associate	VBN
cord-262786-otxpc46a	255	34	with	with	IN
cord-262786-otxpc46a	255	35	Middle	Middle	NNP
cord-262786-otxpc46a	255	36	East	East	NNP
cord-262786-otxpc46a	255	37	respiratory	respiratory	JJ
cord-262786-otxpc46a	255	38	syndrome	syndrome	NN
cord-262786-otxpc46a	255	39	corona	corona	NN
cord-262786-otxpc46a	255	40	virus	virus	NN
cord-262786-otxpc46a	255	41	(	(	-LRB-
cord-262786-otxpc46a	255	42	MERS	MERS	NNP
cord-262786-otxpc46a	255	43	-	-	HYPH
cord-262786-otxpc46a	255	44	CoV	CoV	NNP
cord-262786-otxpc46a	255	45	)	)	-RRB-
cord-262786-otxpc46a	256	1	Are	be	VBP
cord-262786-otxpc46a	256	2	we	-PRON-	PRP
cord-262786-otxpc46a	256	3	facing	face	VBG
cord-262786-otxpc46a	256	4	a	a	DT
cord-262786-otxpc46a	256	5	crashing	crash	VBG
cord-262786-otxpc46a	256	6	Antidepressant	antidepressant	JJ
cord-262786-otxpc46a	256	7	activity	activity	NN
cord-262786-otxpc46a	256	8	of	of	IN
cord-262786-otxpc46a	256	9	anti	anti	JJ
cord-262786-otxpc46a	256	10	-	-	JJ
cord-262786-otxpc46a	256	11	cytokine	cytokine	JJ
cord-262786-otxpc46a	256	12	treatment	treatment	NN
cord-262786-otxpc46a	256	13	:	:	:
cord-262786-otxpc46a	256	14	a	a	DT
cord-262786-otxpc46a	256	15	systematic	systematic	JJ
cord-262786-otxpc46a	256	16	review	review	NN
cord-262786-otxpc46a	256	17	and	and	CC
cord-262786-otxpc46a	256	18	meta	meta	NNP
cord-262786-otxpc46a	256	19	-	-	HYPH
cord-262786-otxpc46a	256	20	analysis	analysis	NN
cord-262786-otxpc46a	256	21	of	of	IN
cord-262786-otxpc46a	256	22	clinical	clinical	JJ
cord-262786-otxpc46a	256	23	trials	trial	NNS
cord-262786-otxpc46a	256	24	of	of	IN
cord-262786-otxpc46a	256	25	chronic	chronic	JJ
cord-262786-otxpc46a	256	26	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	256	27	conditions	condition	NNS
cord-262786-otxpc46a	256	28	Sofosbuvir	Sofosbuvir	NNP
cord-262786-otxpc46a	256	29	protects	protect	VBZ
cord-262786-otxpc46a	256	30	human	human	JJ
cord-262786-otxpc46a	256	31	brain	brain	NN
cord-262786-otxpc46a	256	32	organoids	organoid	NNS
cord-262786-otxpc46a	256	33	against	against	IN
cord-262786-otxpc46a	256	34	SARS	SARS	NNP
cord-262786-otxpc46a	256	35	-	-	HYPH
cord-262786-otxpc46a	256	36	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	256	37	.	.	.
cord-262786-otxpc46a	257	1	bioRxiv	biorxiv	DT
cord-262786-otxpc46a	257	2	Immune	immune	JJ
cord-262786-otxpc46a	257	3	-	-	HYPH
cord-262786-otxpc46a	257	4	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	257	5	parameters	parameter	NNS
cord-262786-otxpc46a	257	6	in	in	IN
cord-262786-otxpc46a	257	7	COVID-19	covid-19	JJ
cord-262786-otxpc46a	257	8	cases	case	NNS
cord-262786-otxpc46a	257	9	:	:	:
cord-262786-otxpc46a	257	10	a	a	DT
cord-262786-otxpc46a	257	11	systematic	systematic	JJ
cord-262786-otxpc46a	257	12	review	review	NN
cord-262786-otxpc46a	257	13	and	and	CC
cord-262786-otxpc46a	257	14	meta	meta	NNP
cord-262786-otxpc46a	257	15	-	-	HYPH
cord-262786-otxpc46a	257	16	analysis	analysis	NN
cord-262786-otxpc46a	257	17	Neuropathogenesis	Neuropathogenesis	NNP
cord-262786-otxpc46a	257	18	and	and	CC
cord-262786-otxpc46a	257	19	neurologic	neurologic	JJ
cord-262786-otxpc46a	257	20	manifestations	manifestation	NNS
cord-262786-otxpc46a	257	21	of	of	IN
cord-262786-otxpc46a	257	22	the	the	DT
cord-262786-otxpc46a	257	23	coronaviruses	coronaviruse	NNS
cord-262786-otxpc46a	257	24	in	in	IN
cord-262786-otxpc46a	257	25	the	the	DT
cord-262786-otxpc46a	257	26	age	age	NN
cord-262786-otxpc46a	257	27	of	of	IN
cord-262786-otxpc46a	257	28	coronavirus	coronavirus	NN
cord-262786-otxpc46a	257	29	disease	disease	NN
cord-262786-otxpc46a	257	30	2019	2019	CD
cord-262786-otxpc46a	257	31	:	:	:
cord-262786-otxpc46a	257	32	a	a	DT
cord-262786-otxpc46a	257	33	review	review	NN
cord-262786-otxpc46a	257	34	Dynamics	dynamic	NNS
cord-262786-otxpc46a	257	35	and	and	CC
cord-262786-otxpc46a	257	36	significance	significance	NN
cord-262786-otxpc46a	257	37	of	of	IN
cord-262786-otxpc46a	257	38	the	the	DT
cord-262786-otxpc46a	257	39	antibody	antibody	NN
cord-262786-otxpc46a	257	40	response	response	NN
cord-262786-otxpc46a	257	41	to	to	IN
cord-262786-otxpc46a	257	42	SARS	SARS	NNP
cord-262786-otxpc46a	257	43	-	-	HYPH
cord-262786-otxpc46a	257	44	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	257	45	infection	infection	NN
cord-262786-otxpc46a	257	46	medRxiv	medRxiv	VBZ
cord-262786-otxpc46a	257	47	Antibody	Antibody	NNP
cord-262786-otxpc46a	257	48	detection	detection	NN
cord-262786-otxpc46a	257	49	and	and	CC
cord-262786-otxpc46a	257	50	dynamic	dynamic	JJ
cord-262786-otxpc46a	257	51	characteristics	characteristic	NNS
cord-262786-otxpc46a	257	52	in	in	IN
cord-262786-otxpc46a	257	53	patients	patient	NNS
cord-262786-otxpc46a	257	54	with	with	IN
cord-262786-otxpc46a	257	55	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	258	1	Is	be	VBZ
cord-262786-otxpc46a	258	2	a	a	DT
cord-262786-otxpc46a	258	3	"	"	``
cord-262786-otxpc46a	258	4	cytokine	cytokine	NN
cord-262786-otxpc46a	258	5	storm	storm	NN
cord-262786-otxpc46a	258	6	"	"	''
cord-262786-otxpc46a	258	7	relevant	relevant	JJ
cord-262786-otxpc46a	258	8	to	to	IN
cord-262786-otxpc46a	258	9	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	258	10	Neuroinflammation	Neuroinflammation	NNP
cord-262786-otxpc46a	258	11	in	in	IN
cord-262786-otxpc46a	258	12	Alzheimer	Alzheimer	NNP
cord-262786-otxpc46a	258	13	's	's	POS
cord-262786-otxpc46a	258	14	disease	disease	NN
cord-262786-otxpc46a	258	15	:	:	:
cord-262786-otxpc46a	258	16	current	current	JJ
cord-262786-otxpc46a	258	17	evidence	evidence	NN
cord-262786-otxpc46a	258	18	and	and	CC
cord-262786-otxpc46a	258	19	future	future	JJ
cord-262786-otxpc46a	258	20	directions	direction	NNS
cord-262786-otxpc46a	258	21	Genetic	genetic	JJ
cord-262786-otxpc46a	258	22	modification	modification	NN
cord-262786-otxpc46a	258	23	of	of	IN
cord-262786-otxpc46a	258	24	primary	primary	JJ
cord-262786-otxpc46a	258	25	human	human	JJ
cord-262786-otxpc46a	258	26	airway	airway	NN
cord-262786-otxpc46a	258	27	epithelial	epithelial	JJ
cord-262786-otxpc46a	258	28	cultures	culture	NNS
cord-262786-otxpc46a	258	29	-	-	:
cord-262786-otxpc46a	258	30	a	a	DT
cord-262786-otxpc46a	258	31	novel	novel	JJ
cord-262786-otxpc46a	258	32	platform	platform	NN
cord-262786-otxpc46a	258	33	to	to	TO
cord-262786-otxpc46a	258	34	study	study	VB
cord-262786-otxpc46a	258	35	respiratory	respiratory	JJ
cord-262786-otxpc46a	258	36	pathogens	pathogen	NNS
cord-262786-otxpc46a	258	37	Miller	Miller	NNP
cord-262786-otxpc46a	258	38	Fisher	Fisher	NNP
cord-262786-otxpc46a	258	39	Syndrome	Syndrome	NNP
cord-262786-otxpc46a	258	40	and	and	CC
cord-262786-otxpc46a	258	41	polyneuritis	polyneuritis	NNP
cord-262786-otxpc46a	258	42	cranialis	cranialis	NNP
cord-262786-otxpc46a	258	43	in	in	IN
cord-262786-otxpc46a	258	44	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	258	45	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	258	46	related	relate	VBN
cord-262786-otxpc46a	258	47	neuroimaging	neuroimaging	NN
cord-262786-otxpc46a	258	48	findings	finding	NNS
cord-262786-otxpc46a	258	49	:	:	:
cord-262786-otxpc46a	259	1	a	a	DT
cord-262786-otxpc46a	259	2	signal	signal	NN
cord-262786-otxpc46a	259	3	of	of	IN
cord-262786-otxpc46a	259	4	thromboembolic	thromboembolic	JJ
cord-262786-otxpc46a	259	5	complications	complication	NNS
cord-262786-otxpc46a	259	6	and	and	CC
cord-262786-otxpc46a	259	7	a	a	DT
cord-262786-otxpc46a	259	8	strong	strong	JJ
cord-262786-otxpc46a	259	9	prognostic	prognostic	JJ
cord-262786-otxpc46a	259	10	marker	marker	NN
cord-262786-otxpc46a	259	11	of	of	IN
cord-262786-otxpc46a	259	12	poor	poor	JJ
cord-262786-otxpc46a	259	13	patient	patient	NN
cord-262786-otxpc46a	259	14	outcome	outcome	NN
cord-262786-otxpc46a	259	15	Neurobiology	neurobiology	NN
cord-262786-otxpc46a	259	16	of	of	IN
cord-262786-otxpc46a	259	17	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	259	18	Changing	change	VBG
cord-262786-otxpc46a	259	19	dynamics	dynamic	NNS
cord-262786-otxpc46a	259	20	of	of	IN
cord-262786-otxpc46a	259	21	psychoneuroimmunology	psychoneuroimmunology	NN
cord-262786-otxpc46a	259	22	during	during	IN
cord-262786-otxpc46a	259	23	COVID-19	covid-19	CD
cord-262786-otxpc46a	259	24	pandemic	pandemic	JJ
cord-262786-otxpc46a	259	25	Gut	gut	VB
cord-262786-otxpc46a	259	26	microbiome	microbiome	NN
cord-262786-otxpc46a	259	27	alterations	alteration	NNS
cord-262786-otxpc46a	259	28	in	in	IN
cord-262786-otxpc46a	259	29	Alzheimer	Alzheimer	NNP
cord-262786-otxpc46a	259	30	's	's	POS
cord-262786-otxpc46a	259	31	disease	disease	NN
cord-262786-otxpc46a	259	32	Altered	alter	VBD
cord-262786-otxpc46a	259	33	gut	gut	NN
cord-262786-otxpc46a	259	34	microbiota	microbiota	NNS
cord-262786-otxpc46a	259	35	and	and	CC
cord-262786-otxpc46a	259	36	inflammatory	inflammatory	JJ
cord-262786-otxpc46a	259	37	cytokine	cytokine	NN
cord-262786-otxpc46a	259	38	responses	response	NNS
cord-262786-otxpc46a	259	39	in	in	IN
cord-262786-otxpc46a	259	40	patients	patient	NNS
cord-262786-otxpc46a	259	41	with	with	IN
cord-262786-otxpc46a	259	42	Parkinson	Parkinson	NNP
cord-262786-otxpc46a	259	43	's	's	POS
cord-262786-otxpc46a	259	44	disease	disease	NN
cord-262786-otxpc46a	259	45	Human	human	JJ
cord-262786-otxpc46a	259	46	coronavirus	coronavirus	NN
cord-262786-otxpc46a	259	47	OC43	OC43	NNP
cord-262786-otxpc46a	259	48	infection	infection	NN
cord-262786-otxpc46a	259	49	induces	induce	VBZ
cord-262786-otxpc46a	259	50	chronic	chronic	JJ
cord-262786-otxpc46a	259	51	encephalitis	encephalitis	RB
cord-262786-otxpc46a	259	52	leading	lead	VBG
cord-262786-otxpc46a	259	53	to	to	IN
cord-262786-otxpc46a	259	54	disabilities	disability	NNS
cord-262786-otxpc46a	259	55	in	in	IN
cord-262786-otxpc46a	259	56	BALB	BALB	NNP
cord-262786-otxpc46a	259	57	/	/	SYM
cord-262786-otxpc46a	259	58	C	C	NNP
cord-262786-otxpc46a	259	59	mice	mouse	NNS
cord-262786-otxpc46a	259	60	Metabolic	metabolic	JJ
cord-262786-otxpc46a	259	61	connectivity	connectivity	NN
cord-262786-otxpc46a	259	62	in	in	IN
cord-262786-otxpc46a	259	63	Alzheimer	Alzheimer	NNP
cord-262786-otxpc46a	259	64	's	's	POS
cord-262786-otxpc46a	259	65	diseases	disease	NNS
cord-262786-otxpc46a	260	1	The	the	DT
cord-262786-otxpc46a	260	2	role	role	NN
cord-262786-otxpc46a	260	3	of	of	IN
cord-262786-otxpc46a	260	4	high	high	JJ
cord-262786-otxpc46a	260	5	cholesterol	cholesterol	NN
cord-262786-otxpc46a	260	6	in	in	IN
cord-262786-otxpc46a	260	7	age	age	NN
cord-262786-otxpc46a	260	8	-	-	HYPH
cord-262786-otxpc46a	260	9	related	relate	VBN
cord-262786-otxpc46a	260	10	COVID19	covid19	IN
cord-262786-otxpc46a	260	11	lethality	lethality	NN
cord-262786-otxpc46a	260	12	APOE	APOE	NNP
cord-262786-otxpc46a	260	13	e4	e4	NN
cord-262786-otxpc46a	260	14	genotype	genotype	NN
cord-262786-otxpc46a	260	15	predicts	predict	VBZ
cord-262786-otxpc46a	260	16	severe	severe	JJ
cord-262786-otxpc46a	260	17	COVID-19	covid-19	CD
cord-262786-otxpc46a	260	18	in	in	IN
cord-262786-otxpc46a	260	19	the	the	DT
cord-262786-otxpc46a	260	20	UK	UK	NNP
cord-262786-otxpc46a	260	21	Biobank	Biobank	NNP
cord-262786-otxpc46a	260	22	community	community	NN
cord-262786-otxpc46a	260	23	cohort	cohort	NN
cord-262786-otxpc46a	260	24	Age	Age	NNP
cord-262786-otxpc46a	260	25	,	,	,
cord-262786-otxpc46a	260	26	APOE	APOE	NNP
cord-262786-otxpc46a	260	27	and	and	CC
cord-262786-otxpc46a	260	28	sex	sex	NN
cord-262786-otxpc46a	260	29	:	:	:
cord-262786-otxpc46a	260	30	triad	triad	NNP
cord-262786-otxpc46a	260	31	of	of	IN
cord-262786-otxpc46a	260	32	risk	risk	NN
cord-262786-otxpc46a	260	33	of	of	IN
cord-262786-otxpc46a	260	34	Alzheimer	Alzheimer	NNP
cord-262786-otxpc46a	260	35	's	's	POS
cord-262786-otxpc46a	260	36	disease	disease	NN
cord-262786-otxpc46a	261	1	The	the	DT
cord-262786-otxpc46a	261	2	role	role	NN
cord-262786-otxpc46a	261	3	of	of	IN
cord-262786-otxpc46a	261	4	interleukin-6	interleukin-6	NNP
cord-262786-otxpc46a	261	5	signaling	signal	VBG
cord-262786-otxpc46a	261	6	in	in	IN
cord-262786-otxpc46a	261	7	nervous	nervous	JJ
cord-262786-otxpc46a	261	8	tissue	tissue	NN
cord-262786-otxpc46a	261	9	Potential	potential	JJ
cord-262786-otxpc46a	261	10	novel	novel	JJ
cord-262786-otxpc46a	261	11	role	role	NN
cord-262786-otxpc46a	261	12	of	of	IN
cord-262786-otxpc46a	261	13	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	261	14	in	in	IN
cord-262786-otxpc46a	261	15	Alzheimer	Alzheimer	NNP
cord-262786-otxpc46a	261	16	's	's	POS
cord-262786-otxpc46a	261	17	disease	disease	NN
cord-262786-otxpc46a	261	18	and	and	CC
cord-262786-otxpc46a	261	19	preventative	preventative	JJ
cord-262786-otxpc46a	261	20	mitigation	mitigation	NN
cord-262786-otxpc46a	261	21	strategies	strategy	NNS
cord-262786-otxpc46a	261	22	Parkinson	Parkinson	NNP
cord-262786-otxpc46a	261	23	's	's	POS
cord-262786-otxpc46a	261	24	disease	disease	NN
cord-262786-otxpc46a	261	25	:	:	:
cord-262786-otxpc46a	261	26	autoimmunity	autoimmunity	NN
cord-262786-otxpc46a	261	27	and	and	CC
cord-262786-otxpc46a	261	28	neuroinflammation	neuroinflammation	NN
cord-262786-otxpc46a	261	29	Depopulation	depopulation	NN
cord-262786-otxpc46a	261	30	of	of	IN
cord-262786-otxpc46a	261	31	dense	dense	JJ
cord-262786-otxpc46a	261	32	α	α	NNP
cord-262786-otxpc46a	261	33	-	-	HYPH
cord-262786-otxpc46a	261	34	synuclein	synuclein	NNP
cord-262786-otxpc46a	261	35	aggregates	aggregate	NNS
cord-262786-otxpc46a	261	36	is	be	VBZ
cord-262786-otxpc46a	261	37	associated	associate	VBN
cord-262786-otxpc46a	261	38	with	with	IN
cord-262786-otxpc46a	261	39	rescue	rescue	NN
cord-262786-otxpc46a	261	40	of	of	IN
cord-262786-otxpc46a	261	41	dopamine	dopamine	NNP
cord-262786-otxpc46a	261	42	neuron	neuron	NN
cord-262786-otxpc46a	261	43	dysfunction	dysfunction	NN
cord-262786-otxpc46a	261	44	and	and	CC
cord-262786-otxpc46a	261	45	death	death	NN
cord-262786-otxpc46a	261	46	in	in	IN
cord-262786-otxpc46a	261	47	a	a	DT
cord-262786-otxpc46a	261	48	new	new	JJ
cord-262786-otxpc46a	261	49	Parkinson	Parkinson	NNP
cord-262786-otxpc46a	261	50	's	's	POS
cord-262786-otxpc46a	261	51	disease	disease	NN
cord-262786-otxpc46a	261	52	model	model	NN
cord-262786-otxpc46a	262	1	Longitudinal	longitudinal	JJ
cord-262786-otxpc46a	262	2	alterations	alteration	NNS
cord-262786-otxpc46a	262	3	of	of	IN
cord-262786-otxpc46a	262	4	alphasynuclein	alphasynuclein	NNP
cord-262786-otxpc46a	262	5	,	,	,
cord-262786-otxpc46a	262	6	amyloid	amyloid	NN
cord-262786-otxpc46a	262	7	beta	beta	NN
cord-262786-otxpc46a	262	8	,	,	,
cord-262786-otxpc46a	262	9	total	total	JJ
cord-262786-otxpc46a	262	10	,	,	,
cord-262786-otxpc46a	262	11	and	and	CC
cord-262786-otxpc46a	262	12	phosphorylated	phosphorylated	JJ
cord-262786-otxpc46a	262	13	tau	tau	NN
cord-262786-otxpc46a	262	14	in	in	IN
cord-262786-otxpc46a	262	15	cerebrospinal	cerebrospinal	JJ
cord-262786-otxpc46a	262	16	fluid	fluid	NN
cord-262786-otxpc46a	262	17	and	and	CC
cord-262786-otxpc46a	262	18	correlations	correlation	NNS
cord-262786-otxpc46a	262	19	between	between	IN
cord-262786-otxpc46a	262	20	their	-PRON-	PRP$
cord-262786-otxpc46a	262	21	changes	change	NNS
cord-262786-otxpc46a	262	22	in	in	IN
cord-262786-otxpc46a	262	23	Parkinson	Parkinson	NNP
cord-262786-otxpc46a	262	24	's	's	POS
cord-262786-otxpc46a	262	25	disease	disease	NN
cord-262786-otxpc46a	262	26	Association	Association	NNP
cord-262786-otxpc46a	262	27	between	between	IN
cord-262786-otxpc46a	262	28	peripheral	peripheral	JJ
cord-262786-otxpc46a	262	29	inflammation	inflammation	NN
cord-262786-otxpc46a	262	30	and	and	CC
cord-262786-otxpc46a	262	31	DATSCAN	DATSCAN	NNP
cord-262786-otxpc46a	262	32	data	datum	NNS
cord-262786-otxpc46a	262	33	of	of	IN
cord-262786-otxpc46a	262	34	the	the	DT
cord-262786-otxpc46a	262	35	striatal	striatal	JJ
cord-262786-otxpc46a	262	36	nuclei	nucleus	NNS
cord-262786-otxpc46a	262	37	in	in	IN
cord-262786-otxpc46a	262	38	different	different	JJ
cord-262786-otxpc46a	262	39	motor	motor	NN
cord-262786-otxpc46a	262	40	subtypes	subtype	NNS
cord-262786-otxpc46a	262	41	of	of	IN
cord-262786-otxpc46a	262	42	Parkinson	Parkinson	NNP
cord-262786-otxpc46a	262	43	disease	disease	NN
cord-262786-otxpc46a	262	44	Neuroinflammation	Neuroinflammation	NNP
cord-262786-otxpc46a	262	45	as	as	IN
cord-262786-otxpc46a	262	46	a	a	DT
cord-262786-otxpc46a	262	47	factor	factor	NN
cord-262786-otxpc46a	262	48	of	of	IN
cord-262786-otxpc46a	262	49	neurodegenerative	neurodegenerative	JJ
cord-262786-otxpc46a	262	50	disease	disease	NN
cord-262786-otxpc46a	262	51	:	:	:
cord-262786-otxpc46a	262	52	thalidomide	thalidomide	NN
cord-262786-otxpc46a	262	53	analogs	analog	NNS
cord-262786-otxpc46a	262	54	as	as	IN
cord-262786-otxpc46a	262	55	treatments	treatment	NNS
cord-262786-otxpc46a	262	56	Anosmia	Anosmia	NNP
cord-262786-otxpc46a	262	57	is	be	VBZ
cord-262786-otxpc46a	262	58	very	very	RB
cord-262786-otxpc46a	262	59	common	common	JJ
cord-262786-otxpc46a	262	60	in	in	IN
cord-262786-otxpc46a	262	61	the	the	DT
cord-262786-otxpc46a	262	62	Lewy	Lewy	NNP
cord-262786-otxpc46a	262	63	body	body	NN
cord-262786-otxpc46a	262	64	variant	variant	NN
cord-262786-otxpc46a	262	65	of	of	IN
cord-262786-otxpc46a	262	66	Alzheimer	Alzheimer	NNP
cord-262786-otxpc46a	262	67	's	's	POS
cord-262786-otxpc46a	262	68	disease	disease	NN
cord-262786-otxpc46a	262	69	Advances	advance	VBZ
cord-262786-otxpc46a	262	70	in	in	IN
cord-262786-otxpc46a	262	71	markers	marker	NNS
cord-262786-otxpc46a	262	72	of	of	IN
cord-262786-otxpc46a	262	73	prodromal	prodromal	JJ
cord-262786-otxpc46a	262	74	Parkinson	Parkinson	NNP
cord-262786-otxpc46a	262	75	disease	disease	NN
cord-262786-otxpc46a	262	76	Non	Non	NNP
cord-262786-otxpc46a	262	77	-	-	NN
cord-262786-otxpc46a	262	78	motor	motor	JJ
cord-262786-otxpc46a	262	79	features	feature	NNS
cord-262786-otxpc46a	262	80	of	of	IN
cord-262786-otxpc46a	262	81	Parkinson	Parkinson	NNP
cord-262786-otxpc46a	262	82	disease	disease	NN
cord-262786-otxpc46a	262	83	Exploring	explore	VBG
cord-262786-otxpc46a	262	84	white	white	JJ
cord-262786-otxpc46a	262	85	matter	matter	NN
cord-262786-otxpc46a	262	86	microstructure	microstructure	NN
cord-262786-otxpc46a	262	87	and	and	CC
cord-262786-otxpc46a	262	88	olfaction	olfaction	NN
cord-262786-otxpc46a	262	89	dysfunction	dysfunction	NN
cord-262786-otxpc46a	262	90	in	in	IN
cord-262786-otxpc46a	262	91	early	early	JJ
cord-262786-otxpc46a	262	92	parkinson	parkinson	NNP
cord-262786-otxpc46a	262	93	disease	disease	NN
cord-262786-otxpc46a	262	94	:	:	:
cord-262786-otxpc46a	262	95	diffusion	diffusion	NN
cord-262786-otxpc46a	262	96	MRI	MRI	NNP
cord-262786-otxpc46a	262	97	reveals	reveal	VBZ
cord-262786-otxpc46a	262	98	new	new	JJ
cord-262786-otxpc46a	262	99	insight	insight	NN
cord-262786-otxpc46a	262	100	Olfactory	olfactory	NN
cord-262786-otxpc46a	262	101	and	and	CC
cord-262786-otxpc46a	262	102	gustatory	gustatory	JJ
cord-262786-otxpc46a	262	103	dysfunctions	dysfunction	NNS
cord-262786-otxpc46a	262	104	due	due	JJ
cord-262786-otxpc46a	262	105	to	to	IN
cord-262786-otxpc46a	262	106	the	the	DT
cord-262786-otxpc46a	262	107	coronavirus	coronavirus	NN
cord-262786-otxpc46a	262	108	disease	disease	NN
cord-262786-otxpc46a	262	109	(	(	-LRB-
cord-262786-otxpc46a	262	110	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	262	111	)	)	-RRB-
cord-262786-otxpc46a	262	112	:	:	:
cord-262786-otxpc46a	262	113	a	a	DT
cord-262786-otxpc46a	262	114	review	review	NN
cord-262786-otxpc46a	262	115	of	of	IN
cord-262786-otxpc46a	262	116	current	current	JJ
cord-262786-otxpc46a	262	117	evidence	evidence	NN
cord-262786-otxpc46a	262	118	Olfactory	olfactory	JJ
cord-262786-otxpc46a	262	119	dysfunction	dysfunction	NN
cord-262786-otxpc46a	262	120	in	in	IN
cord-262786-otxpc46a	262	121	coronavirus	coronavirus	NN
cord-262786-otxpc46a	262	122	disease	disease	NN
cord-262786-otxpc46a	262	123	2019	2019	CD
cord-262786-otxpc46a	262	124	patients	patient	NNS
cord-262786-otxpc46a	262	125	:	:	:
cord-262786-otxpc46a	262	126	observational	observational	NNP
cord-262786-otxpc46a	262	127	cohort	cohort	NN
cord-262786-otxpc46a	262	128	study	study	NN
cord-262786-otxpc46a	262	129	and	and	CC
cord-262786-otxpc46a	262	130	systematic	systematic	JJ
cord-262786-otxpc46a	262	131	review	review	NN
cord-262786-otxpc46a	262	132	Coronaviruses	Coronaviruses	NNPS
cord-262786-otxpc46a	262	133	and	and	CC
cord-262786-otxpc46a	262	134	the	the	DT
cord-262786-otxpc46a	262	135	chemical	chemical	NN
cord-262786-otxpc46a	262	136	senses	sense	NNS
cord-262786-otxpc46a	262	137	:	:	:
cord-262786-otxpc46a	262	138	past	past	NN
cord-262786-otxpc46a	262	139	,	,	,
cord-262786-otxpc46a	262	140	present	present	JJ
cord-262786-otxpc46a	262	141	,	,	,
cord-262786-otxpc46a	262	142	and	and	CC
cord-262786-otxpc46a	262	143	future	future	JJ
cord-262786-otxpc46a	262	144	Expression	expression	NN
cord-262786-otxpc46a	262	145	of	of	IN
cord-262786-otxpc46a	262	146	the	the	DT
cord-262786-otxpc46a	262	147	SARS	SARS	NNP
cord-262786-otxpc46a	262	148	-	-	HYPH
cord-262786-otxpc46a	262	149	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	262	150	entry	entry	NN
cord-262786-otxpc46a	262	151	proteins	protein	NNS
cord-262786-otxpc46a	262	152	,	,	,
cord-262786-otxpc46a	262	153	ACE2	ACE2	NNP
cord-262786-otxpc46a	262	154	and	and	CC
cord-262786-otxpc46a	262	155	TMPRSS2	TMPRSS2	NNP
cord-262786-otxpc46a	262	156	,	,	,
cord-262786-otxpc46a	262	157	in	in	IN
cord-262786-otxpc46a	262	158	cells	cell	NNS
cord-262786-otxpc46a	262	159	of	of	IN
cord-262786-otxpc46a	262	160	the	the	DT
cord-262786-otxpc46a	262	161	olfactory	olfactory	JJ
cord-262786-otxpc46a	262	162	epithelium	epithelium	NN
cord-262786-otxpc46a	262	163	:	:	:
cord-262786-otxpc46a	262	164	identification	identification	NN
cord-262786-otxpc46a	262	165	of	of	IN
cord-262786-otxpc46a	262	166	cell	cell	NN
cord-262786-otxpc46a	262	167	types	type	NNS
cord-262786-otxpc46a	262	168	and	and	CC
cord-262786-otxpc46a	262	169	trends	trend	NNS
cord-262786-otxpc46a	262	170	with	with	IN
cord-262786-otxpc46a	262	171	age	age	NN
cord-262786-otxpc46a	262	172	Olfactory	olfactory	NN
cord-262786-otxpc46a	262	173	transmucosal	transmucosal	NN
cord-262786-otxpc46a	262	174	SARS	SARS	NNP
cord-262786-otxpc46a	262	175	-	-	HYPH
cord-262786-otxpc46a	262	176	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	262	177	invasion	invasion	NN
cord-262786-otxpc46a	262	178	as	as	IN
cord-262786-otxpc46a	262	179	port	port	NN
cord-262786-otxpc46a	262	180	of	of	IN
cord-262786-otxpc46a	262	181	central	central	JJ
cord-262786-otxpc46a	262	182	nervous	nervous	JJ
cord-262786-otxpc46a	262	183	system	system	NN
cord-262786-otxpc46a	262	184	entry	entry	NN
cord-262786-otxpc46a	262	185	in	in	IN
cord-262786-otxpc46a	262	186	COVID-19	covid-19	JJ
cord-262786-otxpc46a	262	187	patients	patient	NNS
cord-262786-otxpc46a	263	1	Different	different	JJ
cord-262786-otxpc46a	263	2	mechanisms	mechanism	NNS
cord-262786-otxpc46a	263	3	of	of	IN
cord-262786-otxpc46a	263	4	inflammation	inflammation	NN
cord-262786-otxpc46a	263	5	induced	induce	VBN
cord-262786-otxpc46a	263	6	in	in	IN
cord-262786-otxpc46a	263	7	virus	virus	NN
cord-262786-otxpc46a	263	8	and	and	CC
cord-262786-otxpc46a	263	9	autoimmune	autoimmune	JJ
cord-262786-otxpc46a	263	10	-	-	HYPH
cord-262786-otxpc46a	263	11	mediated	mediate	VBN
cord-262786-otxpc46a	263	12	models	model	NNS
cord-262786-otxpc46a	263	13	of	of	IN
cord-262786-otxpc46a	263	14	multiple	multiple	JJ
cord-262786-otxpc46a	263	15	sclerosis	sclerosis	NN
cord-262786-otxpc46a	263	16	in	in	IN
cord-262786-otxpc46a	263	17	C57BL6	C57BL6	NNP
cord-262786-otxpc46a	263	18	mice	mouse	NNS
cord-262786-otxpc46a	263	19	Autoimmunity	autoimmunity	NN
cord-262786-otxpc46a	263	20	and	and	CC
cord-262786-otxpc46a	263	21	cytokines	cytokine	NNS
cord-262786-otxpc46a	263	22	in	in	IN
cord-262786-otxpc46a	263	23	Guillain	Guillain	NNP
cord-262786-otxpc46a	263	24	-	-	HYPH
cord-262786-otxpc46a	263	25	Barré	Barré	NNP
cord-262786-otxpc46a	263	26	syndrome	syndrome	NN
cord-262786-otxpc46a	263	27	revisited	revisit	VBD
cord-262786-otxpc46a	263	28	:	:	:
cord-262786-otxpc46a	263	29	review	review	NN
cord-262786-otxpc46a	263	30	of	of	IN
cord-262786-otxpc46a	263	31	pathomechanisms	pathomechanisms	NNP
cord-262786-otxpc46a	263	32	with	with	IN
cord-262786-otxpc46a	263	33	an	an	DT
cord-262786-otxpc46a	263	34	eye	eye	NN
cord-262786-otxpc46a	263	35	on	on	IN
cord-262786-otxpc46a	263	36	therapeutic	therapeutic	JJ
cord-262786-otxpc46a	263	37	options	option	NNS
cord-262786-otxpc46a	263	38	Pathogenesis	Pathogenesis	NNP
cord-262786-otxpc46a	263	39	of	of	IN
cord-262786-otxpc46a	263	40	murine	murine	JJ
cord-262786-otxpc46a	263	41	coronavirus	coronavirus	NN
cord-262786-otxpc46a	263	42	in	in	IN
cord-262786-otxpc46a	263	43	the	the	DT
cord-262786-otxpc46a	263	44	central	central	JJ
cord-262786-otxpc46a	263	45	nervous	nervous	JJ
cord-262786-otxpc46a	263	46	system	system	NN
cord-262786-otxpc46a	264	1	The	the	DT
cord-262786-otxpc46a	264	2	emerging	emerge	VBG
cord-262786-otxpc46a	264	3	spectrum	spectrum	NN
cord-262786-otxpc46a	264	4	of	of	IN
cord-262786-otxpc46a	264	5	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	264	6	neurology	neurology	NNP
cord-262786-otxpc46a	264	7	:	:	:
cord-262786-otxpc46a	264	8	clinical	clinical	JJ
cord-262786-otxpc46a	264	9	,	,	,
cord-262786-otxpc46a	264	10	radiological	radiological	JJ
cord-262786-otxpc46a	264	11	and	and	CC
cord-262786-otxpc46a	264	12	laboratory	laboratory	NN
cord-262786-otxpc46a	264	13	findings	finding	NNS
cord-262786-otxpc46a	265	1	Neurological	neurological	JJ
cord-262786-otxpc46a	265	2	complications	complication	NNS
cord-262786-otxpc46a	265	3	of	of	IN
cord-262786-otxpc46a	265	4	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	265	5	:	:	:
cord-262786-otxpc46a	265	6	a	a	DT
cord-262786-otxpc46a	265	7	preliminary	preliminary	JJ
cord-262786-otxpc46a	265	8	review	review	NN
cord-262786-otxpc46a	265	9	Understanding	understand	VBG
cord-262786-otxpc46a	265	10	the	the	DT
cord-262786-otxpc46a	265	11	neurotropic	neurotropic	NNP
cord-262786-otxpc46a	265	12	characteristics	characteristic	NNS
cord-262786-otxpc46a	265	13	of	of	IN
cord-262786-otxpc46a	265	14	SARS	SARS	NNP
cord-262786-otxpc46a	265	15	-	-	HYPH
cord-262786-otxpc46a	265	16	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	265	17	:	:	:
cord-262786-otxpc46a	265	18	from	from	IN
cord-262786-otxpc46a	265	19	neurological	neurological	JJ
cord-262786-otxpc46a	265	20	manifestations	manifestation	NNS
cord-262786-otxpc46a	265	21	of	of	IN
cord-262786-otxpc46a	265	22	COVID-19	covid-19	CD
cord-262786-otxpc46a	265	23	to	to	IN
cord-262786-otxpc46a	265	24	potential	potential	JJ
cord-262786-otxpc46a	265	25	neurotropic	neurotropic	NNS
cord-262786-otxpc46a	265	26	mechanisms	mechanism	NNS
cord-262786-otxpc46a	266	1	SARS	SARS	NNP
cord-262786-otxpc46a	266	2	-	-	HYPH
cord-262786-otxpc46a	266	3	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	266	4	can	can	MD
cord-262786-otxpc46a	266	5	induce	induce	VB
cord-262786-otxpc46a	266	6	brain	brain	NN
cord-262786-otxpc46a	266	7	and	and	CC
cord-262786-otxpc46a	266	8	spine	spine	NN
cord-262786-otxpc46a	266	9	demyelinating	demyelinate	VBG
cord-262786-otxpc46a	266	10	lesions	lesion	NNS
cord-262786-otxpc46a	266	11	Cerebrovascular	cerebrovascular	JJ
cord-262786-otxpc46a	266	12	disease	disease	NN
cord-262786-otxpc46a	266	13	in	in	IN
cord-262786-otxpc46a	266	14	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	266	15	Disease	Disease	NNP
cord-262786-otxpc46a	266	16	in	in	IN
cord-262786-otxpc46a	266	17	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	266	18	:	:	:
cord-262786-otxpc46a	266	19	Is	be	VBZ
cord-262786-otxpc46a	266	20	there	there	EX
cord-262786-otxpc46a	266	21	a	a	DT
cord-262786-otxpc46a	266	22	higher	high	JJR
cord-262786-otxpc46a	266	23	risk	risk	NN
cord-262786-otxpc46a	266	24	of	of	IN
cord-262786-otxpc46a	266	25	stroke	stroke	NN
cord-262786-otxpc46a	266	26	?	?	.
cord-262786-otxpc46a	267	1	Neurological	neurological	JJ
cord-262786-otxpc46a	267	2	involvement	involvement	NN
cord-262786-otxpc46a	267	3	of	of	IN
cord-262786-otxpc46a	267	4	coronavirus	coronavirus	NN
cord-262786-otxpc46a	267	5	disease	disease	NN
cord-262786-otxpc46a	267	6	2019	2019	CD
cord-262786-otxpc46a	267	7	:	:	:
cord-262786-otxpc46a	267	8	a	a	DT
cord-262786-otxpc46a	267	9	systematic	systematic	JJ
cord-262786-otxpc46a	267	10	review	review	NN
cord-262786-otxpc46a	267	11	Inflammatory	inflammatory	JJ
cord-262786-otxpc46a	267	12	cytokines	cytokine	NNS
cord-262786-otxpc46a	267	13	in	in	IN
cord-262786-otxpc46a	267	14	experimental	experimental	JJ
cord-262786-otxpc46a	267	15	and	and	CC
cord-262786-otxpc46a	267	16	human	human	JJ
cord-262786-otxpc46a	267	17	stroke	stroke	NN
cord-262786-otxpc46a	267	18	Coronavirus	Coronavirus	NNP
cord-262786-otxpc46a	267	19	disease	disease	NN
cord-262786-otxpc46a	267	20	2019	2019	CD
cord-262786-otxpc46a	267	21	and	and	CC
cord-262786-otxpc46a	267	22	stroke	stroke	VB
cord-262786-otxpc46a	267	23	Multiple	multiple	JJ
cord-262786-otxpc46a	267	24	sclerosis	sclerosis	NN
cord-262786-otxpc46a	267	25	following	follow	VBG
cord-262786-otxpc46a	267	26	SARS	SARS	NNP
cord-262786-otxpc46a	267	27	-	-	HYPH
cord-262786-otxpc46a	267	28	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	267	29	infection	infection	NN
cord-262786-otxpc46a	267	30	.	.	.
cord-262786-otxpc46a	268	1	Multiple	multiple	JJ
cord-262786-otxpc46a	268	2	sclerosis	sclerosis	NN
cord-262786-otxpc46a	268	3	and	and	CC
cord-262786-otxpc46a	268	4	related	relate	VBN
cord-262786-otxpc46a	268	5	disorders	disorder	NNS
cord-262786-otxpc46a	269	1	The	the	DT
cord-262786-otxpc46a	269	2	properties	property	NNS
cord-262786-otxpc46a	269	3	of	of	IN
cord-262786-otxpc46a	269	4	cytokines	cytokine	NNS
cord-262786-otxpc46a	269	5	in	in	IN
cord-262786-otxpc46a	269	6	multiple	multiple	JJ
cord-262786-otxpc46a	269	7	sclerosis	sclerosis	NN
cord-262786-otxpc46a	269	8	:	:	:
cord-262786-otxpc46a	269	9	pros	pro	NNS
cord-262786-otxpc46a	269	10	and	and	CC
cord-262786-otxpc46a	269	11	cons	con	NNS
cord-262786-otxpc46a	269	12	Neurological	neurological	JJ
cord-262786-otxpc46a	269	13	manifestations	manifestation	NNS
cord-262786-otxpc46a	269	14	of	of	IN
cord-262786-otxpc46a	269	15	COVID-19	covid-19	JJ
cord-262786-otxpc46a	269	16	and	and	CC
cord-262786-otxpc46a	269	17	other	other	JJ
cord-262786-otxpc46a	269	18	coronavirus	coronavirus	NN
cord-262786-otxpc46a	269	19	infections	infection	NNS
cord-262786-otxpc46a	269	20	:	:	:
cord-262786-otxpc46a	269	21	a	a	DT
cord-262786-otxpc46a	269	22	systematic	systematic	JJ
cord-262786-otxpc46a	269	23	review	review	NN
cord-262786-otxpc46a	269	24	Experimental	experimental	JJ
cord-262786-otxpc46a	269	25	optic	optic	JJ
cord-262786-otxpc46a	269	26	neuritis	neuritis	NN
cord-262786-otxpc46a	269	27	induced	induce	VBN
cord-262786-otxpc46a	269	28	by	by	IN
cord-262786-otxpc46a	269	29	a	a	DT
cord-262786-otxpc46a	269	30	demyelinating	demyelinating	JJ
cord-262786-otxpc46a	269	31	strain	strain	NN
cord-262786-otxpc46a	269	32	of	of	IN
cord-262786-otxpc46a	269	33	mouse	mouse	NN
cord-262786-otxpc46a	269	34	hepatitis	hepatitis	NN
cord-262786-otxpc46a	269	35	virus	virus	NN
cord-262786-otxpc46a	269	36	Guillain	Guillain	NNP
cord-262786-otxpc46a	269	37	-	-	HYPH
cord-262786-otxpc46a	269	38	Barré	Barré	NNP
cord-262786-otxpc46a	269	39	syndrome	syndrome	NN
cord-262786-otxpc46a	269	40	associated	associate	VBN
cord-262786-otxpc46a	269	41	with	with	IN
cord-262786-otxpc46a	269	42	SARS	SARS	NNP
cord-262786-otxpc46a	269	43	-	-	HYPH
cord-262786-otxpc46a	269	44	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	269	45	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	269	46	presenting	present	VBG
cord-262786-otxpc46a	269	47	with	with	IN
cord-262786-otxpc46a	269	48	ophthalmoparesis	ophthalmoparesis	NN
cord-262786-otxpc46a	269	49	from	from	IN
cord-262786-otxpc46a	269	50	cranial	cranial	JJ
cord-262786-otxpc46a	269	51	nerve	nerve	NN
cord-262786-otxpc46a	269	52	palsy	palsy	NN
cord-262786-otxpc46a	270	1	COVID-19-associated	COVID-19-associated	NNP
cord-262786-otxpc46a	270	2	miller	miller	NNP
cord-262786-otxpc46a	270	3	fisher	fisher	NNP
cord-262786-otxpc46a	270	4	syndrome	syndrome	NN
cord-262786-otxpc46a	270	5	:	:	:
cord-262786-otxpc46a	271	1	MRI	MRI	NNP
cord-262786-otxpc46a	271	2	findings	finding	NNS
cord-262786-otxpc46a	272	1	Guillain	Guillain	NNP
cord-262786-otxpc46a	272	2	-	-	HYPH
cord-262786-otxpc46a	272	3	Barré	Barré	NNP
cord-262786-otxpc46a	272	4	syndrome	syndrome	NN
cord-262786-otxpc46a	272	5	:	:	:
cord-262786-otxpc46a	272	6	the	the	DT
cord-262786-otxpc46a	272	7	first	first	RB
cord-262786-otxpc46a	272	8	documented	documented	JJ
cord-262786-otxpc46a	272	9	COVID-19-triggered	covid-19-triggere	VBN
cord-262786-otxpc46a	272	10	autoimmune	autoimmune	JJ
cord-262786-otxpc46a	272	11	neurologic	neurologic	JJ
cord-262786-otxpc46a	272	12	disease	disease	NN
cord-262786-otxpc46a	272	13	:	:	:
cord-262786-otxpc46a	272	14	more	more	JJR
cord-262786-otxpc46a	272	15	to	to	TO
cord-262786-otxpc46a	272	16	come	come	VB
cord-262786-otxpc46a	272	17	with	with	IN
cord-262786-otxpc46a	272	18	myositis	myositis	NN
cord-262786-otxpc46a	272	19	in	in	IN
cord-262786-otxpc46a	272	20	the	the	DT
cord-262786-otxpc46a	272	21	offing	off	VBG
cord-262786-otxpc46a	272	22	Seizures	seizure	NNS
cord-262786-otxpc46a	272	23	associated	associate	VBN
cord-262786-otxpc46a	272	24	with	with	IN
cord-262786-otxpc46a	272	25	coronavirus	coronavirus	NN
cord-262786-otxpc46a	272	26	infections	infection	NNS
cord-262786-otxpc46a	272	27	Multifocal	multifocal	JJ
cord-262786-otxpc46a	272	28	laminar	laminar	JJ
cord-262786-otxpc46a	272	29	cortical	cortical	JJ
cord-262786-otxpc46a	272	30	brain	brain	NN
cord-262786-otxpc46a	272	31	lesions	lesion	NNS
cord-262786-otxpc46a	272	32	:	:	:
cord-262786-otxpc46a	272	33	a	a	DT
cord-262786-otxpc46a	272	34	consistent	consistent	JJ
cord-262786-otxpc46a	272	35	MRI	MRI	NNP
cord-262786-otxpc46a	272	36	finding	finding	NN
cord-262786-otxpc46a	272	37	in	in	IN
cord-262786-otxpc46a	272	38	neuro	neuro	NNP
cord-262786-otxpc46a	272	39	-	-	HYPH
cord-262786-otxpc46a	272	40	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	272	41	patients	patient	NNS
cord-262786-otxpc46a	273	1	A	a	DT
cord-262786-otxpc46a	273	2	review	review	NN
cord-262786-otxpc46a	273	3	of	of	IN
cord-262786-otxpc46a	273	4	pathophysiology	pathophysiology	NN
cord-262786-otxpc46a	273	5	and	and	CC
cord-262786-otxpc46a	273	6	neuropsychiatric	neuropsychiatric	JJ
cord-262786-otxpc46a	273	7	manifestations	manifestation	NNS
cord-262786-otxpc46a	273	8	of	of	IN
cord-262786-otxpc46a	273	9	COVID-19	COVID-19	NNP
cord-262786-otxpc46a	273	10	Postinfectious	Postinfectious	NNP
cord-262786-otxpc46a	273	11	brainstem	brainstem	NN
cord-262786-otxpc46a	273	12	encephalitis	encephalitis	RB
cord-262786-otxpc46a	273	13	associated	associate	VBN
cord-262786-otxpc46a	273	14	with	with	IN
cord-262786-otxpc46a	273	15	SARS	SARS	NNP
cord-262786-otxpc46a	273	16	-	-	HYPH
cord-262786-otxpc46a	273	17	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	273	18	Evolution	evolution	NN
cord-262786-otxpc46a	273	19	and	and	CC
cord-262786-otxpc46a	273	20	resolution	resolution	NN
cord-262786-otxpc46a	273	21	of	of	IN
cord-262786-otxpc46a	273	22	brain	brain	NN
cord-262786-otxpc46a	273	23	involvement	involvement	NN
cord-262786-otxpc46a	273	24	associated	associate	VBN
cord-262786-otxpc46a	273	25	with	with	IN
cord-262786-otxpc46a	273	26	SARS	SARS	NNP
cord-262786-otxpc46a	273	27	-	-	HYPH
cord-262786-otxpc46a	273	28	CoV2	CoV2	NNP
cord-262786-otxpc46a	273	29	infection	infection	NN
cord-262786-otxpc46a	273	30	:	:	:
cord-262786-otxpc46a	273	31	a	a	DT
cord-262786-otxpc46a	273	32	close	close	JJ
cord-262786-otxpc46a	273	33	clinical	clinical	JJ
cord-262786-otxpc46a	273	34	-	-	HYPH
cord-262786-otxpc46a	273	35	paraclinical	paraclinical	NN
cord-262786-otxpc46a	273	36	follow	follow	VB
cord-262786-otxpc46a	273	37	up	up	RP
cord-262786-otxpc46a	273	38	study	study	NN
cord-262786-otxpc46a	273	39	of	of	IN
cord-262786-otxpc46a	273	40	a	a	DT
cord-262786-otxpc46a	273	41	case	case	NN
cord-262786-otxpc46a	273	42	Immune	immune	NN
cord-262786-otxpc46a	273	43	-	-	HYPH
cord-262786-otxpc46a	273	44	mediated	mediate	VBN
cord-262786-otxpc46a	273	45	neurological	neurological	JJ
cord-262786-otxpc46a	273	46	syndromes	syndrome	NNS
cord-262786-otxpc46a	273	47	in	in	IN
cord-262786-otxpc46a	273	48	SARS	SARS	NNP
cord-262786-otxpc46a	273	49	-	-	HYPH
cord-262786-otxpc46a	273	50	CoV-2-infected	cov-2-infecte	VBN
cord-262786-otxpc46a	273	51	patients	patient	NNS
cord-262786-otxpc46a	274	1	COVID-19	covid-19	VB
cord-262786-otxpc46a	274	2	:	:	:
cord-262786-otxpc46a	274	3	The	the	DT
cord-262786-otxpc46a	274	4	inflammation	inflammation	NN
cord-262786-otxpc46a	274	5	link	link	NN
cord-262786-otxpc46a	274	6	and	and	CC
cord-262786-otxpc46a	274	7	the	the	DT
cord-262786-otxpc46a	274	8	role	role	NN
cord-262786-otxpc46a	274	9	of	of	IN
cord-262786-otxpc46a	274	10	nutrition	nutrition	NN
cord-262786-otxpc46a	274	11	in	in	IN
cord-262786-otxpc46a	274	12	potential	potential	JJ
cord-262786-otxpc46a	274	13	mitigation	mitigation	NN
cord-262786-otxpc46a	274	14	Therapeutic	therapeutic	JJ
cord-262786-otxpc46a	274	15	strategies	strategy	NNS
cord-262786-otxpc46a	274	16	in	in	IN
cord-262786-otxpc46a	274	17	the	the	DT
cord-262786-otxpc46a	274	18	development	development	NN
cord-262786-otxpc46a	274	19	of	of	IN
cord-262786-otxpc46a	274	20	anti	anti	JJ
cord-262786-otxpc46a	274	21	-	-	JJ
cord-262786-otxpc46a	274	22	viral	viral	JJ
cord-262786-otxpc46a	274	23	drugs	drug	NNS
cord-262786-otxpc46a	274	24	and	and	CC
cord-262786-otxpc46a	274	25	vaccines	vaccine	NNS
cord-262786-otxpc46a	274	26	against	against	IN
cord-262786-otxpc46a	274	27	SARS	SARS	NNP
cord-262786-otxpc46a	274	28	-	-	HYPH
cord-262786-otxpc46a	274	29	CoV-2	CoV-2	NNP
cord-262786-otxpc46a	274	30	infection	infection	NN
cord-262786-otxpc46a	275	1	Publisher	publisher	NN
cord-262786-otxpc46a	275	2	's	's	POS
cord-262786-otxpc46a	275	3	Note	Note	NNP
cord-262786-otxpc46a	275	4	Springer	Springer	NNP
cord-262786-otxpc46a	275	5	Nature	Nature	NNP
cord-262786-otxpc46a	275	6	remains	remain	VBZ
cord-262786-otxpc46a	275	7	neutral	neutral	JJ
cord-262786-otxpc46a	275	8	with	with	IN
cord-262786-otxpc46a	275	9	regard	regard	NN
cord-262786-otxpc46a	275	10	to	to	IN
cord-262786-otxpc46a	275	11	jurisdictional	jurisdictional	JJ
cord-262786-otxpc46a	275	12	claims	claim	NNS
cord-262786-otxpc46a	275	13	in	in	IN
cord-262786-otxpc46a	275	14	published	publish	VBN
cord-262786-otxpc46a	275	15	maps	map	NNS
cord-262786-otxpc46a	275	16	and	and	CC
cord-262786-otxpc46a	275	17	institutional	institutional	JJ
cord-262786-otxpc46a	275	18	affiliations	affiliation	NNS
cord-262786-otxpc46a	276	1	The	the	DT
cord-262786-otxpc46a	276	2	authors	author	NNS
cord-262786-otxpc46a	276	3	declare	declare	VBP
cord-262786-otxpc46a	276	4	that	that	IN
cord-262786-otxpc46a	276	5	they	-PRON-	PRP
cord-262786-otxpc46a	276	6	have	have	VBP
cord-262786-otxpc46a	276	7	no	no	DT
cord-262786-otxpc46a	276	8	conflict	conflict	NN
cord-262786-otxpc46a	276	9	of	of	IN
cord-262786-otxpc46a	276	10	interest	interest	NN
cord-262786-otxpc46a	276	11	.	.	.