id sid tid token lemma pos cord-256217-fnjer0e0 1 1 key key JJ cord-256217-fnjer0e0 2 1 : : : cord-256217-fnjer0e0 2 2 cord-256217-fnjer0e0 cord-256217-fnjer0e0 DT cord-256217-fnjer0e0 2 3 authors author NNS cord-256217-fnjer0e0 2 4 : : : cord-256217-fnjer0e0 2 5 Neri Neri NNP cord-256217-fnjer0e0 2 6 , , , cord-256217-fnjer0e0 2 7 Piergiorgio Piergiorgio NNP cord-256217-fnjer0e0 2 8 ; ; : cord-256217-fnjer0e0 2 9 Pichi Pichi NNP cord-256217-fnjer0e0 2 10 , , , cord-256217-fnjer0e0 2 11 Francesco Francesco NNP cord-256217-fnjer0e0 2 12 title title NN cord-256217-fnjer0e0 2 13 : : : cord-256217-fnjer0e0 2 14 COVID-19 covid-19 VB cord-256217-fnjer0e0 2 15 and and CC cord-256217-fnjer0e0 2 16 the the DT cord-256217-fnjer0e0 2 17 eye eye NN cord-256217-fnjer0e0 2 18 immunity immunity NN cord-256217-fnjer0e0 2 19 : : : cord-256217-fnjer0e0 2 20 lesson lesson NN cord-256217-fnjer0e0 2 21 learned learn VBN cord-256217-fnjer0e0 2 22 from from IN cord-256217-fnjer0e0 2 23 the the DT cord-256217-fnjer0e0 2 24 past past NN cord-256217-fnjer0e0 2 25 and and CC cord-256217-fnjer0e0 2 26 possible possible JJ cord-256217-fnjer0e0 2 27 new new JJ cord-256217-fnjer0e0 2 28 therapeutic therapeutic JJ cord-256217-fnjer0e0 2 29 insights insight NNS cord-256217-fnjer0e0 2 30 date date NN cord-256217-fnjer0e0 2 31 : : : cord-256217-fnjer0e0 2 32 2020 2020 CD cord-256217-fnjer0e0 2 33 - - HYPH cord-256217-fnjer0e0 2 34 04 04 CD cord-256217-fnjer0e0 2 35 - - SYM cord-256217-fnjer0e0 2 36 20 20 CD cord-256217-fnjer0e0 2 37 journal journal NN cord-256217-fnjer0e0 2 38 : : : cord-256217-fnjer0e0 3 1 Int Int NNP cord-256217-fnjer0e0 3 2 Ophthalmol Ophthalmol NNP cord-256217-fnjer0e0 3 3 DOI DOI NNP cord-256217-fnjer0e0 3 4 : : : cord-256217-fnjer0e0 3 5 10.1007 10.1007 CD cord-256217-fnjer0e0 3 6 / / SYM cord-256217-fnjer0e0 3 7 s10792 s10792 NN cord-256217-fnjer0e0 3 8 - - HYPH cord-256217-fnjer0e0 3 9 020 020 CD cord-256217-fnjer0e0 4 1 -01389 -01389 : cord-256217-fnjer0e0 4 2 - - : cord-256217-fnjer0e0 4 3 2 2 CD cord-256217-fnjer0e0 4 4 sha sha NN cord-256217-fnjer0e0 4 5 : : : cord-256217-fnjer0e0 4 6 5bc55e0dd200e698ef6bb147e4945b7fabde6428 5bc55e0dd200e698ef6bb147e4945b7fabde6428 CD cord-256217-fnjer0e0 4 7 doc_id doc_id CD cord-256217-fnjer0e0 4 8 : : : cord-256217-fnjer0e0 4 9 256217 256217 CD cord-256217-fnjer0e0 4 10 cord_uid cord_uid NNS cord-256217-fnjer0e0 4 11 : : : cord-256217-fnjer0e0 5 1 fnjer0e0 fnjer0e0 NNP cord-256217-fnjer0e0 5 2 nan nan NNP cord-256217-fnjer0e0 5 3 Corona Corona NNP cord-256217-fnjer0e0 5 4 virus virus NN cord-256217-fnjer0e0 5 5 represents represent VBZ cord-256217-fnjer0e0 5 6 nowadays nowadays RB cord-256217-fnjer0e0 5 7 the the DT cord-256217-fnjer0e0 5 8 hot hot JJ cord-256217-fnjer0e0 5 9 topic topic NN cord-256217-fnjer0e0 5 10 in in IN cord-256217-fnjer0e0 5 11 the the DT cord-256217-fnjer0e0 5 12 scientific scientific JJ cord-256217-fnjer0e0 5 13 world world NN cord-256217-fnjer0e0 5 14 due due IN cord-256217-fnjer0e0 5 15 to to IN cord-256217-fnjer0e0 5 16 the the DT cord-256217-fnjer0e0 5 17 outbreak outbreak NN cord-256217-fnjer0e0 5 18 of of IN cord-256217-fnjer0e0 5 19 a a DT cord-256217-fnjer0e0 5 20 novel novel JJ cord-256217-fnjer0e0 5 21 serotype serotype NN cord-256217-fnjer0e0 5 22 formerly formerly RB cord-256217-fnjer0e0 5 23 named name VBN cord-256217-fnjer0e0 5 24 coronavirus coronavirus NN cord-256217-fnjer0e0 5 25 disease disease NN cord-256217-fnjer0e0 5 26 ( ( -LRB- cord-256217-fnjer0e0 5 27 COVID)-19 covid)-19 JJ cord-256217-fnjer0e0 5 28 and and CC cord-256217-fnjer0e0 5 29 now now RB cord-256217-fnjer0e0 5 30 identified identify VBN cord-256217-fnjer0e0 5 31 as as IN cord-256217-fnjer0e0 5 32 severe severe JJ cord-256217-fnjer0e0 5 33 acute acute JJ cord-256217-fnjer0e0 5 34 respiratory respiratory JJ cord-256217-fnjer0e0 5 35 syndrome syndrome NN cord-256217-fnjer0e0 5 36 ( ( -LRB- cord-256217-fnjer0e0 5 37 SARS)-COV-2 sars)-cov-2 JJ cord-256217-fnjer0e0 5 38 [ [ -LRB- cord-256217-fnjer0e0 5 39 1 1 CD cord-256217-fnjer0e0 5 40 ] ] -RRB- cord-256217-fnjer0e0 5 41 . . . cord-256217-fnjer0e0 6 1 The the DT cord-256217-fnjer0e0 6 2 disease disease NN cord-256217-fnjer0e0 6 3 has have VBZ cord-256217-fnjer0e0 6 4 been be VBN cord-256217-fnjer0e0 6 5 firstly firstly RB cord-256217-fnjer0e0 6 6 reported report VBN cord-256217-fnjer0e0 6 7 in in IN cord-256217-fnjer0e0 6 8 Wuhan Wuhan NNP cord-256217-fnjer0e0 6 9 , , , cord-256217-fnjer0e0 6 10 Yubei Yubei NNP cord-256217-fnjer0e0 6 11 District District NNP cord-256217-fnjer0e0 6 12 of of IN cord-256217-fnjer0e0 6 13 the the DT cord-256217-fnjer0e0 6 14 Republic Republic NNP cord-256217-fnjer0e0 6 15 of of IN cord-256217-fnjer0e0 6 16 China China NNP cord-256217-fnjer0e0 6 17 , , , cord-256217-fnjer0e0 6 18 when when WRB cord-256217-fnjer0e0 6 19 in in IN cord-256217-fnjer0e0 6 20 December December NNP cord-256217-fnjer0e0 6 21 2019 2019 CD cord-256217-fnjer0e0 6 22 its -PRON- PRP$ cord-256217-fnjer0e0 6 23 outbreak outbreak NN cord-256217-fnjer0e0 6 24 affected affect VBN cord-256217-fnjer0e0 6 25 around around IN cord-256217-fnjer0e0 6 26 80,000 80,000 CD cord-256217-fnjer0e0 6 27 people people NNS cord-256217-fnjer0e0 6 28 and and CC cord-256217-fnjer0e0 6 29 provoked provoke VBD cord-256217-fnjer0e0 6 30 about about IN cord-256217-fnjer0e0 6 31 3000 3000 CD cord-256217-fnjer0e0 6 32 deaths death NNS cord-256217-fnjer0e0 6 33 due due JJ cord-256217-fnjer0e0 6 34 to to IN cord-256217-fnjer0e0 6 35 pulmonary pulmonary JJ cord-256217-fnjer0e0 6 36 complications complication NNS cord-256217-fnjer0e0 6 37 [ [ -LRB- cord-256217-fnjer0e0 6 38 1 1 CD cord-256217-fnjer0e0 6 39 ] ] -RRB- cord-256217-fnjer0e0 6 40 . . . cord-256217-fnjer0e0 7 1 The the DT cord-256217-fnjer0e0 7 2 virus virus NN cord-256217-fnjer0e0 7 3 rapidly rapidly RB cord-256217-fnjer0e0 7 4 spread spread VBD cord-256217-fnjer0e0 7 5 all all RB cord-256217-fnjer0e0 7 6 over over IN cord-256217-fnjer0e0 7 7 the the DT cord-256217-fnjer0e0 7 8 world world NN cord-256217-fnjer0e0 7 9 and and CC cord-256217-fnjer0e0 7 10 was be VBD cord-256217-fnjer0e0 7 11 recognized recognize VBN cord-256217-fnjer0e0 7 12 as as IN cord-256217-fnjer0e0 7 13 a a DT cord-256217-fnjer0e0 7 14 pandemic pandemic NN cord-256217-fnjer0e0 7 15 by by IN cord-256217-fnjer0e0 7 16 the the DT cord-256217-fnjer0e0 7 17 World World NNP cord-256217-fnjer0e0 7 18 Health Health NNP cord-256217-fnjer0e0 7 19 Organization Organization NNP cord-256217-fnjer0e0 7 20 ( ( -LRB- cord-256217-fnjer0e0 7 21 WHO who WP cord-256217-fnjer0e0 7 22 ) ) -RRB- cord-256217-fnjer0e0 7 23 on on IN cord-256217-fnjer0e0 7 24 March March NNP cord-256217-fnjer0e0 7 25 11 11 CD cord-256217-fnjer0e0 7 26 , , , cord-256217-fnjer0e0 7 27 2020 2020 CD cord-256217-fnjer0e0 7 28 [ [ -LRB- cord-256217-fnjer0e0 7 29 2 2 CD cord-256217-fnjer0e0 7 30 ] ] -RRB- cord-256217-fnjer0e0 7 31 . . . cord-256217-fnjer0e0 8 1 In in IN cord-256217-fnjer0e0 8 2 4 4 CD cord-256217-fnjer0e0 8 3 months month NNS cord-256217-fnjer0e0 8 4 , , , cord-256217-fnjer0e0 8 5 the the DT cord-256217-fnjer0e0 8 6 disease disease NN cord-256217-fnjer0e0 8 7 was be VBD cord-256217-fnjer0e0 8 8 recognized recognize VBN cord-256217-fnjer0e0 8 9 in in IN cord-256217-fnjer0e0 8 10 about about RB cord-256217-fnjer0e0 8 11 1,521,252 1,521,252 CD cord-256217-fnjer0e0 8 12 people people NNS cord-256217-fnjer0e0 8 13 and and CC cord-256217-fnjer0e0 8 14 made make VBD cord-256217-fnjer0e0 8 15 92,798 92,798 CD cord-256217-fnjer0e0 8 16 victims victim NNS cord-256217-fnjer0e0 8 17 mainly mainly RB cord-256217-fnjer0e0 8 18 in in IN cord-256217-fnjer0e0 8 19 elderly elderly JJ cord-256217-fnjer0e0 8 20 and and CC cord-256217-fnjer0e0 8 21 compromised compromised JJ cord-256217-fnjer0e0 8 22 patients patient NNS cord-256217-fnjer0e0 8 23 . . . cord-256217-fnjer0e0 9 1 On on IN cord-256217-fnjer0e0 9 2 an an DT cord-256217-fnjer0e0 9 3 official official JJ cord-256217-fnjer0e0 9 4 report report NN cord-256217-fnjer0e0 9 5 released release VBN cord-256217-fnjer0e0 9 6 on on IN cord-256217-fnjer0e0 9 7 April April NNP cord-256217-fnjer0e0 9 8 10 10 CD cord-256217-fnjer0e0 9 9 , , , cord-256217-fnjer0e0 9 10 2020 2020 CD cord-256217-fnjer0e0 9 11 , , , cord-256217-fnjer0e0 9 12 SARS SARS NNP cord-256217-fnjer0e0 9 13 - - HYPH cord-256217-fnjer0e0 9 14 COV-2 COV-2 NNP cord-256217-fnjer0e0 9 15 carried carry VBD cord-256217-fnjer0e0 9 16 a a DT cord-256217-fnjer0e0 9 17 mortality mortality NN cord-256217-fnjer0e0 9 18 rate rate NN cord-256217-fnjer0e0 9 19 around around IN cord-256217-fnjer0e0 9 20 6.1 6.1 CD cord-256217-fnjer0e0 9 21 % % NN cord-256217-fnjer0e0 9 22 compared compare VBN cord-256217-fnjer0e0 9 23 to to IN cord-256217-fnjer0e0 9 24 influenza influenza NN cord-256217-fnjer0e0 9 25 that that WDT cord-256217-fnjer0e0 9 26 is be VBZ cord-256217-fnjer0e0 9 27 supposed suppose VBN cord-256217-fnjer0e0 9 28 be be VB cord-256217-fnjer0e0 9 29 around around IN cord-256217-fnjer0e0 9 30 1 1 CD cord-256217-fnjer0e0 9 31 % % NN cord-256217-fnjer0e0 9 32 [ [ -LRB- cord-256217-fnjer0e0 9 33 3 3 CD cord-256217-fnjer0e0 9 34 ] ] -RRB- cord-256217-fnjer0e0 9 35 . . . cord-256217-fnjer0e0 10 1 All all DT cord-256217-fnjer0e0 10 2 countries country NNS cord-256217-fnjer0e0 10 3 are be VBP cord-256217-fnjer0e0 10 4 encountering encounter VBG cord-256217-fnjer0e0 10 5 massive massive JJ cord-256217-fnjer0e0 10 6 and and CC cord-256217-fnjer0e0 10 7 dramatic dramatic JJ cord-256217-fnjer0e0 10 8 problems problem NNS cord-256217-fnjer0e0 10 9 in in IN cord-256217-fnjer0e0 10 10 terms term NNS cord-256217-fnjer0e0 10 11 of of IN cord-256217-fnjer0e0 10 12 prevention prevention NN cord-256217-fnjer0e0 10 13 and and CC cord-256217-fnjer0e0 10 14 sustainability sustainability NN cord-256217-fnjer0e0 10 15 of of IN cord-256217-fnjer0e0 10 16 treatments treatment NNS cord-256217-fnjer0e0 10 17 for for IN cord-256217-fnjer0e0 10 18 this this DT cord-256217-fnjer0e0 10 19 disease disease NN cord-256217-fnjer0e0 10 20 which which WDT cord-256217-fnjer0e0 10 21 does do VBZ cord-256217-fnjer0e0 10 22 not not RB cord-256217-fnjer0e0 10 23 have have VB cord-256217-fnjer0e0 10 24 a a DT cord-256217-fnjer0e0 10 25 universally universally RB cord-256217-fnjer0e0 10 26 agreed agree VBN cord-256217-fnjer0e0 10 27 therapeutic therapeutic JJ cord-256217-fnjer0e0 10 28 protocol protocol NN cord-256217-fnjer0e0 10 29 . . . cord-256217-fnjer0e0 11 1 Current current JJ cord-256217-fnjer0e0 11 2 management management NN cord-256217-fnjer0e0 11 3 of of IN cord-256217-fnjer0e0 11 4 COVID-19 COVID-19 NNP cord-256217-fnjer0e0 11 5 is be VBZ cord-256217-fnjer0e0 11 6 mainly mainly RB cord-256217-fnjer0e0 11 7 supportive supportive JJ cord-256217-fnjer0e0 11 8 , , , cord-256217-fnjer0e0 11 9 even even RB cord-256217-fnjer0e0 11 10 though though IN cord-256217-fnjer0e0 11 11 the the DT cord-256217-fnjer0e0 11 12 medical medical JJ cord-256217-fnjer0e0 11 13 literature literature NN cord-256217-fnjer0e0 11 14 has have VBZ cord-256217-fnjer0e0 11 15 reported report VBN cord-256217-fnjer0e0 11 16 several several JJ cord-256217-fnjer0e0 11 17 rescue rescue NN cord-256217-fnjer0e0 11 18 strategies strategy NNS cord-256217-fnjer0e0 11 19 which which WDT cord-256217-fnjer0e0 11 20 might may MD cord-256217-fnjer0e0 11 21 minimize minimize VB cord-256217-fnjer0e0 11 22 the the DT cord-256217-fnjer0e0 11 23 mortality mortality NN cord-256217-fnjer0e0 11 24 rate rate NN cord-256217-fnjer0e0 11 25 in in IN cord-256217-fnjer0e0 11 26 those those DT cord-256217-fnjer0e0 11 27 who who WP cord-256217-fnjer0e0 11 28 have have VBP cord-256217-fnjer0e0 11 29 severe severe JJ cord-256217-fnjer0e0 11 30 pulmonary pulmonary JJ cord-256217-fnjer0e0 11 31 complications complication NNS cord-256217-fnjer0e0 11 32 . . . cord-256217-fnjer0e0 12 1 Hydroxychloroquine Hydroxychloroquine NNP cord-256217-fnjer0e0 12 2 and and CC cord-256217-fnjer0e0 12 3 azithromycin azithromycin NNP cord-256217-fnjer0e0 12 4 combination combination NN cord-256217-fnjer0e0 12 5 seems seem VBZ cord-256217-fnjer0e0 12 6 to to TO cord-256217-fnjer0e0 12 7 be be VB cord-256217-fnjer0e0 12 8 a a DT cord-256217-fnjer0e0 12 9 valid valid JJ cord-256217-fnjer0e0 12 10 possible possible JJ cord-256217-fnjer0e0 12 11 therapeutic therapeutic JJ cord-256217-fnjer0e0 12 12 protocol protocol NN cord-256217-fnjer0e0 12 13 [ [ -LRB- cord-256217-fnjer0e0 12 14 4 4 CD cord-256217-fnjer0e0 12 15 ] ] -RRB- cord-256217-fnjer0e0 12 16 and and CC cord-256217-fnjer0e0 12 17 is be VBZ cord-256217-fnjer0e0 12 18 currently currently RB cord-256217-fnjer0e0 12 19 under under IN cord-256217-fnjer0e0 12 20 urgent urgent JJ cord-256217-fnjer0e0 12 21 investigation investigation NN cord-256217-fnjer0e0 12 22 . . . cord-256217-fnjer0e0 13 1 Unfortunately unfortunately RB cord-256217-fnjer0e0 13 2 , , , cord-256217-fnjer0e0 13 3 the the DT cord-256217-fnjer0e0 13 4 real real JJ cord-256217-fnjer0e0 13 5 challenge challenge NN cord-256217-fnjer0e0 13 6 is be VBZ cord-256217-fnjer0e0 13 7 represented represent VBN cord-256217-fnjer0e0 13 8 by by IN cord-256217-fnjer0e0 13 9 those those DT cord-256217-fnjer0e0 13 10 cases case NNS cord-256217-fnjer0e0 13 11 where where WRB cord-256217-fnjer0e0 13 12 the the DT cord-256217-fnjer0e0 13 13 severe severe JJ cord-256217-fnjer0e0 13 14 form form NN cord-256217-fnjer0e0 13 15 of of IN cord-256217-fnjer0e0 13 16 SARS SARS NNP cord-256217-fnjer0e0 13 17 - - HYPH cord-256217-fnjer0e0 13 18 COV-2 COV-2 NNP cord-256217-fnjer0e0 13 19 interstitial interstitial JJ cord-256217-fnjer0e0 13 20 pneumonia pneumonia NN cord-256217-fnjer0e0 13 21 occurs occur VBZ cord-256217-fnjer0e0 13 22 , , , cord-256217-fnjer0e0 13 23 with with IN cord-256217-fnjer0e0 13 24 acute acute JJ cord-256217-fnjer0e0 13 25 respiratory respiratory JJ cord-256217-fnjer0e0 13 26 distress distress NN cord-256217-fnjer0e0 13 27 syndrome syndrome NN cord-256217-fnjer0e0 13 28 ( ( -LRB- cord-256217-fnjer0e0 13 29 ARDS ARDS NNP cord-256217-fnjer0e0 13 30 ) ) -RRB- cord-256217-fnjer0e0 13 31 that that WDT cord-256217-fnjer0e0 13 32 might may MD cord-256217-fnjer0e0 13 33 lead lead VB cord-256217-fnjer0e0 13 34 to to IN cord-256217-fnjer0e0 13 35 fatal fatal JJ cord-256217-fnjer0e0 13 36 events event NNS cord-256217-fnjer0e0 13 37 [ [ -LRB- cord-256217-fnjer0e0 13 38 5 5 CD cord-256217-fnjer0e0 13 39 ] ] -RRB- cord-256217-fnjer0e0 13 40 . . . cord-256217-fnjer0e0 14 1 The the DT cord-256217-fnjer0e0 14 2 urgent urgent JJ cord-256217-fnjer0e0 14 3 need need NN cord-256217-fnjer0e0 14 4 to to TO cord-256217-fnjer0e0 14 5 find find VB cord-256217-fnjer0e0 14 6 a a DT cord-256217-fnjer0e0 14 7 treatment treatment NN cord-256217-fnjer0e0 14 8 for for IN cord-256217-fnjer0e0 14 9 such such JJ cord-256217-fnjer0e0 14 10 lifethreatening lifethreatening JJ cord-256217-fnjer0e0 14 11 condition condition NN cord-256217-fnjer0e0 14 12 has have VBZ cord-256217-fnjer0e0 14 13 led lead VBN cord-256217-fnjer0e0 14 14 to to IN cord-256217-fnjer0e0 14 15 off off IN cord-256217-fnjer0e0 14 16 - - HYPH cord-256217-fnjer0e0 14 17 label label NN cord-256217-fnjer0e0 14 18 approaches approach NNS cord-256217-fnjer0e0 14 19 based base VBN cord-256217-fnjer0e0 14 20 on on IN cord-256217-fnjer0e0 14 21 the the DT cord-256217-fnjer0e0 14 22 possible possible JJ cord-256217-fnjer0e0 14 23 hypercytokinemia hypercytokinemia NN cord-256217-fnjer0e0 14 24 with with IN cord-256217-fnjer0e0 14 25 multiorgan multiorgan NNP cord-256217-fnjer0e0 14 26 failure failure NN cord-256217-fnjer0e0 14 27 [ [ -LRB- cord-256217-fnjer0e0 14 28 6 6 CD cord-256217-fnjer0e0 14 29 ] ] -RRB- cord-256217-fnjer0e0 14 30 . . . cord-256217-fnjer0e0 15 1 An an DT cord-256217-fnjer0e0 15 2 experimental experimental JJ cord-256217-fnjer0e0 15 3 protocol protocol NN cord-256217-fnjer0e0 15 4 using use VBG cord-256217-fnjer0e0 15 5 an an DT cord-256217-fnjer0e0 15 6 anti anti JJ cord-256217-fnjer0e0 15 7 - - JJ cord-256217-fnjer0e0 15 8 interleukin interleukin JJ cord-256217-fnjer0e0 15 9 ( ( -LRB- cord-256217-fnjer0e0 15 10 IL)-6 IL)-6 NNP cord-256217-fnjer0e0 15 11 receptor receptor NN cord-256217-fnjer0e0 15 12 monoclonal monoclonal JJ cord-256217-fnjer0e0 15 13 antibody antibody NN cord-256217-fnjer0e0 15 14 named name VBN cord-256217-fnjer0e0 15 15 tocilizumab tocilizumab NNP cord-256217-fnjer0e0 16 1 ( ( -LRB- cord-256217-fnjer0e0 16 2 Actemra Actemra NNP cord-256217-fnjer0e0 16 3 , , , cord-256217-fnjer0e0 16 4 Roche Roche NNP cord-256217-fnjer0e0 16 5 Pharma Pharma NNP cord-256217-fnjer0e0 16 6 ( ( -LRB- cord-256217-fnjer0e0 16 7 Schweiz Schweiz NNP cord-256217-fnjer0e0 16 8 ) ) -RRB- cord-256217-fnjer0e0 16 9 Ltd Ltd NNP cord-256217-fnjer0e0 16 10 , , , cord-256217-fnjer0e0 16 11 B2084B21 B2084B21 NNP cord-256217-fnjer0e0 16 12 ) ) -RRB- cord-256217-fnjer0e0 16 13 has have VBZ cord-256217-fnjer0e0 16 14 given give VBN cord-256217-fnjer0e0 16 15 hope hope NN cord-256217-fnjer0e0 16 16 of of IN cord-256217-fnjer0e0 16 17 a a DT cord-256217-fnjer0e0 16 18 possible possible JJ cord-256217-fnjer0e0 16 19 effective effective JJ cord-256217-fnjer0e0 16 20 therapy therapy NN cord-256217-fnjer0e0 16 21 . . . cord-256217-fnjer0e0 17 1 Tocilizumab Tocilizumab NNP cord-256217-fnjer0e0 17 2 was be VBD cord-256217-fnjer0e0 17 3 used use VBN cord-256217-fnjer0e0 17 4 as as IN cord-256217-fnjer0e0 17 5 a a DT cord-256217-fnjer0e0 17 6 rescue rescue NN cord-256217-fnjer0e0 17 7 treatment treatment NN cord-256217-fnjer0e0 17 8 in in IN cord-256217-fnjer0e0 17 9 a a DT cord-256217-fnjer0e0 17 10 series series NN cord-256217-fnjer0e0 17 11 of of IN cord-256217-fnjer0e0 17 12 patients patient NNS cord-256217-fnjer0e0 17 13 affected affect VBN cord-256217-fnjer0e0 17 14 by by IN cord-256217-fnjer0e0 17 15 severe severe JJ cord-256217-fnjer0e0 17 16 interstitial interstitial JJ cord-256217-fnjer0e0 17 17 pneumonia pneumonia NN cord-256217-fnjer0e0 17 18 by by IN cord-256217-fnjer0e0 17 19 Zhang Zhang NNP cord-256217-fnjer0e0 17 20 et et NNP cord-256217-fnjer0e0 17 21 al al NNP cord-256217-fnjer0e0 17 22 . . . cord-256217-fnjer0e0 18 1 [ [ -LRB- cord-256217-fnjer0e0 18 2 7 7 CD cord-256217-fnjer0e0 18 3 ] ] -RRB- cord-256217-fnjer0e0 18 4 which which WDT cord-256217-fnjer0e0 18 5 observed observe VBD cord-256217-fnjer0e0 18 6 an an DT cord-256217-fnjer0e0 18 7 evident evident JJ cord-256217-fnjer0e0 18 8 improvement improvement NN cord-256217-fnjer0e0 18 9 in in IN cord-256217-fnjer0e0 18 10 both both DT cord-256217-fnjer0e0 18 11 systemic systemic JJ cord-256217-fnjer0e0 18 12 symptoms symptom NNS cord-256217-fnjer0e0 18 13 and and CC cord-256217-fnjer0e0 18 14 the the DT cord-256217-fnjer0e0 18 15 specific specific JJ cord-256217-fnjer0e0 18 16 pulmonary pulmonary JJ cord-256217-fnjer0e0 18 17 impairment impairment NN cord-256217-fnjer0e0 18 18 within within IN cord-256217-fnjer0e0 18 19 a a DT cord-256217-fnjer0e0 18 20 few few JJ cord-256217-fnjer0e0 18 21 days day NNS cord-256217-fnjer0e0 18 22 . . . cord-256217-fnjer0e0 19 1 These these DT cord-256217-fnjer0e0 19 2 interesting interesting JJ cord-256217-fnjer0e0 19 3 results result NNS cord-256217-fnjer0e0 19 4 were be VBD cord-256217-fnjer0e0 19 5 followed follow VBN cord-256217-fnjer0e0 19 6 by by IN cord-256217-fnjer0e0 19 7 a a DT cord-256217-fnjer0e0 19 8 series series NN cord-256217-fnjer0e0 19 9 of of IN cord-256217-fnjer0e0 19 10 other other JJ cord-256217-fnjer0e0 19 11 publications publication NNS cord-256217-fnjer0e0 19 12 speculating speculate VBG cord-256217-fnjer0e0 19 13 on on IN cord-256217-fnjer0e0 19 14 how how WRB cord-256217-fnjer0e0 19 15 the the DT cord-256217-fnjer0e0 19 16 inhibition inhibition NN cord-256217-fnjer0e0 19 17 of of IN cord-256217-fnjer0e0 19 18 immune immune JJ cord-256217-fnjer0e0 19 19 checkpoints checkpoint NNS cord-256217-fnjer0e0 19 20 might may MD cord-256217-fnjer0e0 19 21 have have VB cord-256217-fnjer0e0 19 22 exerted exert VBN cord-256217-fnjer0e0 19 23 a a DT cord-256217-fnjer0e0 19 24 possible possible JJ cord-256217-fnjer0e0 19 25 good good JJ cord-256217-fnjer0e0 19 26 control control NN cord-256217-fnjer0e0 19 27 of of IN cord-256217-fnjer0e0 19 28 the the DT cord-256217-fnjer0e0 19 29 disease disease NN cord-256217-fnjer0e0 19 30 . . . cord-256217-fnjer0e0 20 1 On on IN cord-256217-fnjer0e0 20 2 the the DT cord-256217-fnjer0e0 20 3 other other JJ cord-256217-fnjer0e0 20 4 hand hand NN cord-256217-fnjer0e0 20 5 , , , cord-256217-fnjer0e0 20 6 the the DT cord-256217-fnjer0e0 20 7 severe severe JJ cord-256217-fnjer0e0 20 8 contingent contingent JJ cord-256217-fnjer0e0 20 9 situation situation NN cord-256217-fnjer0e0 20 10 created create VBN cord-256217-fnjer0e0 20 11 by by IN cord-256217-fnjer0e0 20 12 the the DT cord-256217-fnjer0e0 20 13 outbreak outbreak NN cord-256217-fnjer0e0 20 14 of of IN cord-256217-fnjer0e0 20 15 SARS SARS NNP cord-256217-fnjer0e0 20 16 - - HYPH cord-256217-fnjer0e0 20 17 COV-2 COV-2 NNP cord-256217-fnjer0e0 20 18 infection infection NN cord-256217-fnjer0e0 20 19 does do VBZ cord-256217-fnjer0e0 20 20 not not RB cord-256217-fnjer0e0 20 21 allow allow VB cord-256217-fnjer0e0 20 22 to to TO cord-256217-fnjer0e0 20 23 have have VB cord-256217-fnjer0e0 20 24 good good JJ cord-256217-fnjer0e0 20 25 models model NNS cord-256217-fnjer0e0 20 26 to to TO cord-256217-fnjer0e0 20 27 rely rely VB cord-256217-fnjer0e0 20 28 on on IN cord-256217-fnjer0e0 20 29 . . . cord-256217-fnjer0e0 21 1 In in IN cord-256217-fnjer0e0 21 2 the the DT cord-256217-fnjer0e0 21 3 medical medical JJ cord-256217-fnjer0e0 21 4 literature literature NN cord-256217-fnjer0e0 21 5 , , , cord-256217-fnjer0e0 21 6 SARS SARS NNP cord-256217-fnjer0e0 21 7 coronavirus coronavirus NN cord-256217-fnjer0e0 21 8 is be VBZ cord-256217-fnjer0e0 21 9 associated associate VBN cord-256217-fnjer0e0 21 10 with with IN cord-256217-fnjer0e0 21 11 the the DT cord-256217-fnjer0e0 21 12 occurrence occurrence NN cord-256217-fnjer0e0 21 13 of of IN cord-256217-fnjer0e0 21 14 hemophagocytic hemophagocytic JJ cord-256217-fnjer0e0 21 15 lymphohistiocytosis lymphohistiocytosis NNP cord-256217-fnjer0e0 21 16 ( ( -LRB- cord-256217-fnjer0e0 21 17 sHLH sHLH NNP cord-256217-fnjer0e0 21 18 ) ) -RRB- cord-256217-fnjer0e0 21 19 which which WDT cord-256217-fnjer0e0 21 20 represents represent VBZ cord-256217-fnjer0e0 21 21 a a DT cord-256217-fnjer0e0 21 22 lifethreatening lifethreatening JJ cord-256217-fnjer0e0 21 23 hyperinflammatory hyperinflammatory NN cord-256217-fnjer0e0 21 24 syndrome syndrome NN cord-256217-fnjer0e0 21 25 leading lead VBG cord-256217-fnjer0e0 21 26 to to IN cord-256217-fnjer0e0 21 27 a a DT cord-256217-fnjer0e0 21 28 rapid rapid JJ cord-256217-fnjer0e0 21 29 multiorgan multiorgan NN cord-256217-fnjer0e0 21 30 deterioration deterioration NN cord-256217-fnjer0e0 21 31 due due IN cord-256217-fnjer0e0 21 32 to to IN cord-256217-fnjer0e0 21 33 severe severe JJ cord-256217-fnjer0e0 21 34 hypercytokinemia hypercytokinemia NN cord-256217-fnjer0e0 21 35 [ [ -LRB- cord-256217-fnjer0e0 21 36 6 6 CD cord-256217-fnjer0e0 21 37 ] ] -RRB- cord-256217-fnjer0e0 21 38 . . . cord-256217-fnjer0e0 22 1 At at IN cord-256217-fnjer0e0 22 2 this this DT cord-256217-fnjer0e0 22 3 stage stage NN cord-256217-fnjer0e0 22 4 , , , cord-256217-fnjer0e0 22 5 can can MD cord-256217-fnjer0e0 22 6 the the DT cord-256217-fnjer0e0 22 7 ocular ocular JJ cord-256217-fnjer0e0 22 8 immune immune JJ cord-256217-fnjer0e0 22 9 system system NN cord-256217-fnjer0e0 22 10 represent represent VBP cord-256217-fnjer0e0 22 11 a a DT cord-256217-fnjer0e0 22 12 valid valid JJ cord-256217-fnjer0e0 22 13 model model NN cord-256217-fnjer0e0 22 14 upon upon IN cord-256217-fnjer0e0 22 15 which which WDT cord-256217-fnjer0e0 22 16 to to TO cord-256217-fnjer0e0 22 17 rely rely VB cord-256217-fnjer0e0 22 18 in in IN cord-256217-fnjer0e0 22 19 order order NN cord-256217-fnjer0e0 22 20 to to TO cord-256217-fnjer0e0 22 21 hypothesize hypothesize VB cord-256217-fnjer0e0 22 22 a a DT cord-256217-fnjer0e0 22 23 possible possible JJ cord-256217-fnjer0e0 22 24 therapeutic therapeutic JJ cord-256217-fnjer0e0 22 25 strategy strategy NN cord-256217-fnjer0e0 22 26 ? ? . cord-256217-fnjer0e0 23 1 In in IN cord-256217-fnjer0e0 23 2 1990 1990 CD cord-256217-fnjer0e0 23 3 , , , cord-256217-fnjer0e0 23 4 Robbins Robbins NNP cord-256217-fnjer0e0 23 5 et et NNP cord-256217-fnjer0e0 23 6 al al NNP cord-256217-fnjer0e0 23 7 . . NNP cord-256217-fnjer0e0 23 8 reported report VBD cord-256217-fnjer0e0 23 9 on on IN cord-256217-fnjer0e0 23 10 a a DT cord-256217-fnjer0e0 23 11 possible possible JJ cord-256217-fnjer0e0 23 12 animal animal NN cord-256217-fnjer0e0 23 13 model model NN cord-256217-fnjer0e0 23 14 where where WRB cord-256217-fnjer0e0 23 15 murine murine JJ cord-256217-fnjer0e0 23 16 coronavirus coronavirus NN cord-256217-fnjer0e0 23 17 induced induce VBD cord-256217-fnjer0e0 23 18 an an DT cord-256217-fnjer0e0 23 19 acute acute JJ cord-256217-fnjer0e0 23 20 and and CC cord-256217-fnjer0e0 23 21 long long RB cord-256217-fnjer0e0 23 22 - - HYPH cord-256217-fnjer0e0 23 23 lasting last VBG cord-256217-fnjer0e0 23 24 disease disease NN cord-256217-fnjer0e0 23 25 of of IN cord-256217-fnjer0e0 23 26 the the DT cord-256217-fnjer0e0 23 27 retina retina NN cord-256217-fnjer0e0 23 28 [ [ -LRB- cord-256217-fnjer0e0 23 29 8 8 CD cord-256217-fnjer0e0 23 30 ] ] -RRB- cord-256217-fnjer0e0 23 31 . . . cord-256217-fnjer0e0 24 1 This this DT cord-256217-fnjer0e0 24 2 model model NN cord-256217-fnjer0e0 24 3 was be VBD cord-256217-fnjer0e0 24 4 identified identify VBN cord-256217-fnjer0e0 24 5 as as IN cord-256217-fnjer0e0 24 6 experimental experimental JJ cord-256217-fnjer0e0 24 7 coronavirus coronavirus NN cord-256217-fnjer0e0 24 8 retinopathy retinopathy NN cord-256217-fnjer0e0 24 9 ( ( -LRB- cord-256217-fnjer0e0 24 10 ECOR ECOR NNP cord-256217-fnjer0e0 24 11 ) ) -RRB- cord-256217-fnjer0e0 24 12 [ [ -LRB- cord-256217-fnjer0e0 24 13 8 8 CD cord-256217-fnjer0e0 24 14 ] ] -RRB- cord-256217-fnjer0e0 24 15 . . . cord-256217-fnjer0e0 25 1 Few few JJ cord-256217-fnjer0e0 25 2 months month NNS cord-256217-fnjer0e0 25 3 later later RB cord-256217-fnjer0e0 25 4 , , , cord-256217-fnjer0e0 25 5 the the DT cord-256217-fnjer0e0 25 6 same same JJ cord-256217-fnjer0e0 25 7 group group NN cord-256217-fnjer0e0 25 8 of of IN cord-256217-fnjer0e0 25 9 researchers researcher NNS cord-256217-fnjer0e0 25 10 reported report VBD cord-256217-fnjer0e0 25 11 that that IN cord-256217-fnjer0e0 25 12 murine murine JJ cord-256217-fnjer0e0 25 13 coronavirus coronavirus NN cord-256217-fnjer0e0 25 14 had have VBD cord-256217-fnjer0e0 25 15 a a DT cord-256217-fnjer0e0 25 16 specific specific JJ cord-256217-fnjer0e0 25 17 retinotropism retinotropism NN cord-256217-fnjer0e0 25 18 when when WRB cord-256217-fnjer0e0 25 19 introduced introduce VBN cord-256217-fnjer0e0 25 20 by by IN cord-256217-fnjer0e0 25 21 several several JJ cord-256217-fnjer0e0 25 22 direct direct JJ cord-256217-fnjer0e0 25 23 routes route NNS cord-256217-fnjer0e0 25 24 [ [ -LRB- cord-256217-fnjer0e0 25 25 9 9 CD cord-256217-fnjer0e0 25 26 ] ] -RRB- cord-256217-fnjer0e0 25 27 . . . cord-256217-fnjer0e0 26 1 The the DT cord-256217-fnjer0e0 26 2 researchers researcher NNS cord-256217-fnjer0e0 26 3 found find VBD cord-256217-fnjer0e0 26 4 that that IN cord-256217-fnjer0e0 26 5 the the DT cord-256217-fnjer0e0 26 6 viral viral JJ cord-256217-fnjer0e0 26 7 insult insult NN cord-256217-fnjer0e0 26 8 leads lead VBZ cord-256217-fnjer0e0 26 9 to to IN cord-256217-fnjer0e0 26 10 a a DT cord-256217-fnjer0e0 26 11 progressive progressive JJ cord-256217-fnjer0e0 26 12 impairment impairment NN cord-256217-fnjer0e0 26 13 of of IN cord-256217-fnjer0e0 26 14 all all PDT cord-256217-fnjer0e0 26 15 the the DT cord-256217-fnjer0e0 26 16 structures structure NNS cord-256217-fnjer0e0 26 17 of of IN cord-256217-fnjer0e0 26 18 the the DT cord-256217-fnjer0e0 26 19 retinal retinal JJ cord-256217-fnjer0e0 26 20 tissue tissue NN cord-256217-fnjer0e0 26 21 , , , cord-256217-fnjer0e0 26 22 including include VBG cord-256217-fnjer0e0 26 23 photoreceptors photoreceptor NNS cord-256217-fnjer0e0 26 24 and and CC cord-256217-fnjer0e0 26 25 retinal retinal JJ cord-256217-fnjer0e0 26 26 pigment pigment NN cord-256217-fnjer0e0 26 27 epithelium epithelium NN cord-256217-fnjer0e0 26 28 ( ( -LRB- cord-256217-fnjer0e0 26 29 RPE RPE NNP cord-256217-fnjer0e0 26 30 ) ) -RRB- cord-256217-fnjer0e0 26 31 . . . cord-256217-fnjer0e0 27 1 Murine murine JJ cord-256217-fnjer0e0 27 2 coronavirus coronavirus NN cord-256217-fnjer0e0 27 3 showed show VBD cord-256217-fnjer0e0 27 4 an an DT cord-256217-fnjer0e0 27 5 evident evident JJ cord-256217-fnjer0e0 27 6 tropism tropism NN cord-256217-fnjer0e0 27 7 to to IN cord-256217-fnjer0e0 27 8 the the DT cord-256217-fnjer0e0 27 9 neural neural JJ cord-256217-fnjer0e0 27 10 tissue tissue NN cord-256217-fnjer0e0 27 11 of of IN cord-256217-fnjer0e0 27 12 the the DT cord-256217-fnjer0e0 27 13 retina retina NN cord-256217-fnjer0e0 27 14 which which WDT cord-256217-fnjer0e0 27 15 was be VBD cord-256217-fnjer0e0 27 16 independent independent JJ cord-256217-fnjer0e0 27 17 of of IN cord-256217-fnjer0e0 27 18 route route NN cord-256217-fnjer0e0 27 19 of of IN cord-256217-fnjer0e0 27 20 inoculation inoculation NN cord-256217-fnjer0e0 27 21 , , , cord-256217-fnjer0e0 27 22 such such JJ cord-256217-fnjer0e0 27 23 as as IN cord-256217-fnjer0e0 27 24 onto onto IN cord-256217-fnjer0e0 27 25 the the DT cord-256217-fnjer0e0 27 26 cornea cornea NN cord-256217-fnjer0e0 27 27 , , , cord-256217-fnjer0e0 27 28 the the DT cord-256217-fnjer0e0 27 29 anterior anterior NNP cord-256217-fnjer0e0 27 30 chamber chamber NN cord-256217-fnjer0e0 27 31 ( ( -LRB- cord-256217-fnjer0e0 27 32 AC AC NNP cord-256217-fnjer0e0 27 33 ) ) -RRB- cord-256217-fnjer0e0 27 34 , , , cord-256217-fnjer0e0 27 35 intravitreally intravitreally RB cord-256217-fnjer0e0 27 36 , , , cord-256217-fnjer0e0 27 37 intracerebrally intracerebrally RB cord-256217-fnjer0e0 27 38 , , , cord-256217-fnjer0e0 27 39 or or CC cord-256217-fnjer0e0 27 40 intranasally intranasally RB cord-256217-fnjer0e0 27 41 even even RB cord-256217-fnjer0e0 27 42 . . . cord-256217-fnjer0e0 28 1 Interestingly interestingly RB cord-256217-fnjer0e0 28 2 , , , cord-256217-fnjer0e0 28 3 viral viral JJ cord-256217-fnjer0e0 28 4 antigens antigen NNS cord-256217-fnjer0e0 28 5 were be VBD cord-256217-fnjer0e0 28 6 located locate VBN cord-256217-fnjer0e0 28 7 primarily primarily RB cord-256217-fnjer0e0 28 8 in in IN cord-256217-fnjer0e0 28 9 the the DT cord-256217-fnjer0e0 28 10 inner inner JJ cord-256217-fnjer0e0 28 11 nuclear nuclear JJ cord-256217-fnjer0e0 28 12 layer layer NN cord-256217-fnjer0e0 28 13 , , , cord-256217-fnjer0e0 28 14 photoreceptors photoreceptor NNS cord-256217-fnjer0e0 28 15 , , , cord-256217-fnjer0e0 28 16 Muller Muller NNP cord-256217-fnjer0e0 28 17 cells cell NNS cord-256217-fnjer0e0 28 18 , , , cord-256217-fnjer0e0 28 19 and and CC cord-256217-fnjer0e0 28 20 RPE RPE NNP cord-256217-fnjer0e0 28 21 . . . cord-256217-fnjer0e0 29 1 On on IN cord-256217-fnjer0e0 29 2 the the DT cord-256217-fnjer0e0 29 3 other other JJ cord-256217-fnjer0e0 29 4 hand hand NN cord-256217-fnjer0e0 29 5 , , , cord-256217-fnjer0e0 29 6 at at IN cord-256217-fnjer0e0 29 7 day day NN cord-256217-fnjer0e0 29 8 10 10 CD cord-256217-fnjer0e0 29 9 , , , cord-256217-fnjer0e0 29 10 ganglion ganglion NN cord-256217-fnjer0e0 29 11 cell cell NN cord-256217-fnjer0e0 29 12 layer layer NN cord-256217-fnjer0e0 29 13 was be VBD cord-256217-fnjer0e0 29 14 the the DT cord-256217-fnjer0e0 29 15 only only JJ cord-256217-fnjer0e0 29 16 and and CC cord-256217-fnjer0e0 29 17 still still RB cord-256217-fnjer0e0 29 18 infected infect VBN cord-256217-fnjer0e0 29 19 , , , cord-256217-fnjer0e0 29 20 indicating indicate VBG cord-256217-fnjer0e0 29 21 a a DT cord-256217-fnjer0e0 29 22 spontaneous spontaneous JJ cord-256217-fnjer0e0 29 23 clearance clearance NN cord-256217-fnjer0e0 29 24 of of IN cord-256217-fnjer0e0 29 25 the the DT cord-256217-fnjer0e0 29 26 virus virus NN cord-256217-fnjer0e0 29 27 from from IN cord-256217-fnjer0e0 29 28 the the DT cord-256217-fnjer0e0 29 29 other other JJ cord-256217-fnjer0e0 29 30 retinal retinal JJ cord-256217-fnjer0e0 29 31 tissues tissue NNS cord-256217-fnjer0e0 29 32 . . . cord-256217-fnjer0e0 30 1 This this DT cord-256217-fnjer0e0 30 2 trend trend NN cord-256217-fnjer0e0 30 3 in in IN cord-256217-fnjer0e0 30 4 affecting affect VBG cord-256217-fnjer0e0 30 5 the the DT cord-256217-fnjer0e0 30 6 nervous nervous JJ cord-256217-fnjer0e0 30 7 system system NN cord-256217-fnjer0e0 30 8 might may MD cord-256217-fnjer0e0 30 9 be be VB cord-256217-fnjer0e0 30 10 the the DT cord-256217-fnjer0e0 30 11 case case NN cord-256217-fnjer0e0 30 12 of of IN cord-256217-fnjer0e0 30 13 SARS SARS NNP cord-256217-fnjer0e0 30 14 - - HYPH cord-256217-fnjer0e0 30 15 COV-2 COV-2 NNP cord-256217-fnjer0e0 30 16 as as RB cord-256217-fnjer0e0 30 17 well well RB cord-256217-fnjer0e0 30 18 , , , cord-256217-fnjer0e0 30 19 since since IN cord-256217-fnjer0e0 30 20 a a DT cord-256217-fnjer0e0 30 21 recent recent JJ cord-256217-fnjer0e0 30 22 report report NN cord-256217-fnjer0e0 30 23 described describe VBD cord-256217-fnjer0e0 30 24 Guillan Guillan NNP cord-256217-fnjer0e0 30 25 - - HYPH cord-256217-fnjer0e0 30 26 Barrè Barrè NNP cord-256217-fnjer0e0 30 27 syndrome syndrome NN cord-256217-fnjer0e0 30 28 as as IN cord-256217-fnjer0e0 30 29 the the DT cord-256217-fnjer0e0 30 30 first first JJ cord-256217-fnjer0e0 30 31 manifestation manifestation NN cord-256217-fnjer0e0 30 32 of of IN cord-256217-fnjer0e0 30 33 the the DT cord-256217-fnjer0e0 30 34 disease disease NN cord-256217-fnjer0e0 30 35 [ [ -LRB- cord-256217-fnjer0e0 30 36 10 10 CD cord-256217-fnjer0e0 30 37 ] ] -RRB- cord-256217-fnjer0e0 30 38 . . . cord-256217-fnjer0e0 31 1 Interestingly interestingly RB cord-256217-fnjer0e0 31 2 , , , cord-256217-fnjer0e0 31 3 infection infection NN cord-256217-fnjer0e0 31 4 induces induce VBZ cord-256217-fnjer0e0 31 5 fibrosis fibrosis NN cord-256217-fnjer0e0 31 6 of of IN cord-256217-fnjer0e0 31 7 RPE RPE NNP cord-256217-fnjer0e0 31 8 cells cell NNS cord-256217-fnjer0e0 31 9 as as RB cord-256217-fnjer0e0 31 10 well well RB cord-256217-fnjer0e0 31 11 as as IN cord-256217-fnjer0e0 31 12 moderate moderate JJ cord-256217-fnjer0e0 31 13 retinal retinal JJ cord-256217-fnjer0e0 31 14 atrophy atrophy NN cord-256217-fnjer0e0 31 15 in in IN cord-256217-fnjer0e0 31 16 the the DT cord-256217-fnjer0e0 31 17 long long JJ cord-256217-fnjer0e0 31 18 term term NN cord-256217-fnjer0e0 31 19 , , , cord-256217-fnjer0e0 31 20 which which WDT cord-256217-fnjer0e0 31 21 suggests suggest VBZ cord-256217-fnjer0e0 31 22 a a DT cord-256217-fnjer0e0 31 23 certain certain JJ cord-256217-fnjer0e0 31 24 role role NN cord-256217-fnjer0e0 31 25 played play VBN cord-256217-fnjer0e0 31 26 by by IN cord-256217-fnjer0e0 31 27 fibroblasts fibroblast NNS cord-256217-fnjer0e0 31 28 in in IN cord-256217-fnjer0e0 31 29 attempting attempt VBG cord-256217-fnjer0e0 31 30 a a DT cord-256217-fnjer0e0 31 31 repair repair NN cord-256217-fnjer0e0 31 32 of of IN cord-256217-fnjer0e0 31 33 the the DT cord-256217-fnjer0e0 31 34 damaged damage VBN cord-256217-fnjer0e0 31 35 tissue tissue NN cord-256217-fnjer0e0 31 36 . . . cord-256217-fnjer0e0 32 1 Although although IN cord-256217-fnjer0e0 32 2 ECOR ECOR NNP cord-256217-fnjer0e0 32 3 was be VBD cord-256217-fnjer0e0 32 4 used use VBN cord-256217-fnjer0e0 32 5 to to TO cord-256217-fnjer0e0 32 6 study study VB cord-256217-fnjer0e0 32 7 retinal retinal JJ cord-256217-fnjer0e0 32 8 degeneration degeneration NN cord-256217-fnjer0e0 32 9 specifically specifically RB cord-256217-fnjer0e0 32 10 , , , cord-256217-fnjer0e0 32 11 it -PRON- PRP cord-256217-fnjer0e0 32 12 might may MD cord-256217-fnjer0e0 32 13 represent represent VB cord-256217-fnjer0e0 32 14 a a DT cord-256217-fnjer0e0 32 15 possible possible JJ cord-256217-fnjer0e0 32 16 experimental experimental JJ cord-256217-fnjer0e0 32 17 model model NN cord-256217-fnjer0e0 32 18 for for IN cord-256217-fnjer0e0 32 19 interesting interesting JJ cord-256217-fnjer0e0 32 20 speculations speculation NNS cord-256217-fnjer0e0 32 21 on on IN cord-256217-fnjer0e0 32 22 how how WRB cord-256217-fnjer0e0 32 23 to to TO cord-256217-fnjer0e0 32 24 approach approach VB cord-256217-fnjer0e0 32 25 severe severe JJ cord-256217-fnjer0e0 32 26 SARS SARS NNP cord-256217-fnjer0e0 32 27 - - HYPH cord-256217-fnjer0e0 32 28 COV-2 COV-2 NNP cord-256217-fnjer0e0 32 29 pulmonary pulmonary JJ cord-256217-fnjer0e0 32 30 complications complication NNS cord-256217-fnjer0e0 32 31 . . . cord-256217-fnjer0e0 33 1 Going go VBG cord-256217-fnjer0e0 33 2 through through IN cord-256217-fnjer0e0 33 3 the the DT cord-256217-fnjer0e0 33 4 medical medical JJ cord-256217-fnjer0e0 33 5 literature literature NN cord-256217-fnjer0e0 33 6 , , , cord-256217-fnjer0e0 33 7 very very RB cord-256217-fnjer0e0 33 8 little little JJ cord-256217-fnjer0e0 33 9 information information NN cord-256217-fnjer0e0 33 10 is be VBZ cord-256217-fnjer0e0 33 11 available available JJ cord-256217-fnjer0e0 33 12 on on IN cord-256217-fnjer0e0 33 13 the the DT cord-256217-fnjer0e0 33 14 possible possible JJ cord-256217-fnjer0e0 33 15 role role NN cord-256217-fnjer0e0 33 16 played play VBN cord-256217-fnjer0e0 33 17 by by IN cord-256217-fnjer0e0 33 18 the the DT cord-256217-fnjer0e0 33 19 immune immune JJ cord-256217-fnjer0e0 33 20 system system NN cord-256217-fnjer0e0 33 21 in in IN cord-256217-fnjer0e0 33 22 lung lung NN cord-256217-fnjer0e0 33 23 involvement involvement NN cord-256217-fnjer0e0 33 24 , , , cord-256217-fnjer0e0 33 25 which which WDT cord-256217-fnjer0e0 33 26 shows show VBZ cord-256217-fnjer0e0 33 27 moderate moderate JJ cord-256217-fnjer0e0 33 28 multinucleated multinucleated JJ cord-256217-fnjer0e0 33 29 giant giant JJ cord-256217-fnjer0e0 33 30 cells cell NNS cord-256217-fnjer0e0 33 31 , , , cord-256217-fnjer0e0 33 32 minimal minimal JJ cord-256217-fnjer0e0 33 33 lymphocytes lymphocyte NNS cord-256217-fnjer0e0 33 34 , , , cord-256217-fnjer0e0 33 35 eosinophils eosinophil NNS cord-256217-fnjer0e0 33 36 , , , cord-256217-fnjer0e0 33 37 CD4-positive CD4-positive NNP cord-256217-fnjer0e0 33 38 T t NN cord-256217-fnjer0e0 33 39 cells cell NNS cord-256217-fnjer0e0 33 40 , , , cord-256217-fnjer0e0 33 41 and and CC cord-256217-fnjer0e0 33 42 neutrophils neutrophil NNS cord-256217-fnjer0e0 33 43 [ [ -LRB- cord-256217-fnjer0e0 33 44 11 11 CD cord-256217-fnjer0e0 33 45 ] ] -RRB- cord-256217-fnjer0e0 33 46 . . . cord-256217-fnjer0e0 34 1 Lungs lung NNS cord-256217-fnjer0e0 34 2 blood blood NN cord-256217-fnjer0e0 34 3 vessels vessel NNS cord-256217-fnjer0e0 34 4 of of IN cord-256217-fnjer0e0 34 5 alveolar alveolar NN cord-256217-fnjer0e0 34 6 septum septum NN cord-256217-fnjer0e0 34 7 are be VBP cord-256217-fnjer0e0 34 8 congested congested JJ cord-256217-fnjer0e0 34 9 , , , cord-256217-fnjer0e0 34 10 edematous edematous JJ cord-256217-fnjer0e0 34 11 , , , cord-256217-fnjer0e0 34 12 and and CC cord-256217-fnjer0e0 34 13 widened widen VBD cord-256217-fnjer0e0 34 14 , , , cord-256217-fnjer0e0 34 15 with with IN cord-256217-fnjer0e0 34 16 modest modest JJ cord-256217-fnjer0e0 34 17 infiltration infiltration NN cord-256217-fnjer0e0 34 18 of of IN cord-256217-fnjer0e0 34 19 monocytes monocyte NNS cord-256217-fnjer0e0 34 20 and and CC cord-256217-fnjer0e0 34 21 lymphocytes lymphocyte NNS cord-256217-fnjer0e0 34 22 . . . cord-256217-fnjer0e0 35 1 Hyaline hyaline JJ cord-256217-fnjer0e0 35 2 thrombi thrombi NN cord-256217-fnjer0e0 35 3 are be VBP cord-256217-fnjer0e0 35 4 also also RB cord-256217-fnjer0e0 35 5 found find VBN cord-256217-fnjer0e0 35 6 in in IN cord-256217-fnjer0e0 35 7 a a DT cord-256217-fnjer0e0 35 8 minority minority NN cord-256217-fnjer0e0 35 9 of of IN cord-256217-fnjer0e0 35 10 microvessels microvessel NNS cord-256217-fnjer0e0 35 11 , , , cord-256217-fnjer0e0 35 12 as as RB cord-256217-fnjer0e0 35 13 well well RB cord-256217-fnjer0e0 35 14 as as IN cord-256217-fnjer0e0 35 15 local local JJ cord-256217-fnjer0e0 35 16 hemorrhage hemorrhage NN cord-256217-fnjer0e0 35 17 in in IN cord-256217-fnjer0e0 35 18 lung lung NN cord-256217-fnjer0e0 35 19 tissue tissue NN cord-256217-fnjer0e0 35 20 , , , cord-256217-fnjer0e0 35 21 organization organization NN cord-256217-fnjer0e0 35 22 of of IN cord-256217-fnjer0e0 35 23 exudates exudate NNS cord-256217-fnjer0e0 35 24 in in IN cord-256217-fnjer0e0 35 25 some some DT cord-256217-fnjer0e0 35 26 alveolar alveolar JJ cord-256217-fnjer0e0 35 27 cavities cavity NNS cord-256217-fnjer0e0 35 28 , , , cord-256217-fnjer0e0 35 29 and and CC cord-256217-fnjer0e0 35 30 pulmonary pulmonary JJ cord-256217-fnjer0e0 35 31 interstitial interstitial JJ cord-256217-fnjer0e0 35 32 fibrosis fibrosis NN cord-256217-fnjer0e0 35 33 . . . cord-256217-fnjer0e0 36 1 On on IN cord-256217-fnjer0e0 36 2 the the DT cord-256217-fnjer0e0 36 3 other other JJ cord-256217-fnjer0e0 36 4 hand hand NN cord-256217-fnjer0e0 36 5 , , , cord-256217-fnjer0e0 36 6 all all PDT cord-256217-fnjer0e0 36 7 those those DT cord-256217-fnjer0e0 36 8 findings finding NNS cord-256217-fnjer0e0 36 9 were be VBD cord-256217-fnjer0e0 36 10 taken take VBN cord-256217-fnjer0e0 36 11 postmortem postmortem JJ cord-256217-fnjer0e0 36 12 and and CC cord-256217-fnjer0e0 36 13 there there EX cord-256217-fnjer0e0 36 14 is be VBZ cord-256217-fnjer0e0 36 15 lack lack NN cord-256217-fnjer0e0 36 16 of of IN cord-256217-fnjer0e0 36 17 data datum NNS cord-256217-fnjer0e0 36 18 on on IN cord-256217-fnjer0e0 36 19 different different JJ cord-256217-fnjer0e0 36 20 phases phase NNS cord-256217-fnjer0e0 36 21 of of IN cord-256217-fnjer0e0 36 22 the the DT cord-256217-fnjer0e0 36 23 disease disease NN cord-256217-fnjer0e0 36 24 . . . cord-256217-fnjer0e0 37 1 Looking look VBG cord-256217-fnjer0e0 37 2 at at IN cord-256217-fnjer0e0 37 3 the the DT cord-256217-fnjer0e0 37 4 ECOR ECOR NNP cord-256217-fnjer0e0 37 5 model model NN cord-256217-fnjer0e0 37 6 , , , cord-256217-fnjer0e0 37 7 it -PRON- PRP cord-256217-fnjer0e0 37 8 gives give VBZ cord-256217-fnjer0e0 37 9 the the DT cord-256217-fnjer0e0 37 10 impression impression NN cord-256217-fnjer0e0 37 11 that that IN cord-256217-fnjer0e0 37 12 coronavirus coronavirus NN cord-256217-fnjer0e0 37 13 creates create VBZ cord-256217-fnjer0e0 37 14 two two CD cord-256217-fnjer0e0 37 15 different different JJ cord-256217-fnjer0e0 37 16 phases phase NNS cord-256217-fnjer0e0 37 17 : : : cord-256217-fnjer0e0 37 18 the the DT cord-256217-fnjer0e0 37 19 first first JJ cord-256217-fnjer0e0 37 20 is be VBZ cord-256217-fnjer0e0 37 21 represented represent VBN cord-256217-fnjer0e0 37 22 by by IN cord-256217-fnjer0e0 37 23 the the DT cord-256217-fnjer0e0 37 24 primary primary JJ cord-256217-fnjer0e0 37 25 infection infection NN cord-256217-fnjer0e0 37 26 which which WDT cord-256217-fnjer0e0 37 27 induces induce VBZ cord-256217-fnjer0e0 37 28 the the DT cord-256217-fnjer0e0 37 29 triggering triggering NN cord-256217-fnjer0e0 37 30 of of IN cord-256217-fnjer0e0 37 31 the the DT cord-256217-fnjer0e0 37 32 immune immune JJ cord-256217-fnjer0e0 37 33 system system NN cord-256217-fnjer0e0 37 34 , , , cord-256217-fnjer0e0 37 35 while while IN cord-256217-fnjer0e0 37 36 the the DT cord-256217-fnjer0e0 37 37 second second JJ cord-256217-fnjer0e0 37 38 phase phase NN cord-256217-fnjer0e0 37 39 is be VBZ cord-256217-fnjer0e0 37 40 likely likely JJ cord-256217-fnjer0e0 37 41 to to TO cord-256217-fnjer0e0 37 42 be be VB cord-256217-fnjer0e0 37 43 an an DT cord-256217-fnjer0e0 37 44 autoimmune autoimmune JJ cord-256217-fnjer0e0 37 45 disease disease NN cord-256217-fnjer0e0 37 46 where where WRB cord-256217-fnjer0e0 37 47 the the DT cord-256217-fnjer0e0 37 48 role role NN cord-256217-fnjer0e0 37 49 of of IN cord-256217-fnjer0e0 37 50 the the DT cord-256217-fnjer0e0 37 51 severe severe JJ cord-256217-fnjer0e0 37 52 postviral postviral JJ cord-256217-fnjer0e0 37 53 inflammation inflammation NN cord-256217-fnjer0e0 37 54 represents represent VBZ cord-256217-fnjer0e0 37 55 a a DT cord-256217-fnjer0e0 37 56 severe severe JJ cord-256217-fnjer0e0 37 57 occurrence occurrence NN cord-256217-fnjer0e0 37 58 worth worth NN cord-256217-fnjer0e0 37 59 of of IN cord-256217-fnjer0e0 37 60 prompt prompt JJ cord-256217-fnjer0e0 37 61 intervention intervention NN cord-256217-fnjer0e0 37 62 . . . cord-256217-fnjer0e0 38 1 Coronavirus Coronavirus NNP cord-256217-fnjer0e0 38 2 animal animal NN cord-256217-fnjer0e0 38 3 model model NN cord-256217-fnjer0e0 38 4 suggests suggest VBZ cord-256217-fnjer0e0 38 5 that that IN cord-256217-fnjer0e0 38 6 such such JJ cord-256217-fnjer0e0 38 7 hypothesis hypothesis NN cord-256217-fnjer0e0 38 8 might may MD cord-256217-fnjer0e0 38 9 be be VB cord-256217-fnjer0e0 38 10 justified justify VBN cord-256217-fnjer0e0 38 11 [ [ -LRB- cord-256217-fnjer0e0 38 12 9 9 CD cord-256217-fnjer0e0 38 13 ] ] -RRB- cord-256217-fnjer0e0 38 14 : : : cord-256217-fnjer0e0 38 15 as as IN cord-256217-fnjer0e0 38 16 we -PRON- PRP cord-256217-fnjer0e0 38 17 previously previously RB cord-256217-fnjer0e0 38 18 said say VBD cord-256217-fnjer0e0 38 19 , , , cord-256217-fnjer0e0 38 20 Coronavirus Coronavirus NNP cord-256217-fnjer0e0 38 21 was be VBD cord-256217-fnjer0e0 38 22 detected detect VBN cord-256217-fnjer0e0 38 23 into into IN cord-256217-fnjer0e0 38 24 the the DT cord-256217-fnjer0e0 38 25 ganglion ganglion NN cord-256217-fnjer0e0 38 26 cell cell NN cord-256217-fnjer0e0 38 27 layer layer NN cord-256217-fnjer0e0 38 28 only only RB cord-256217-fnjer0e0 38 29 after after IN cord-256217-fnjer0e0 38 30 10 10 CD cord-256217-fnjer0e0 38 31 days day NNS cord-256217-fnjer0e0 38 32 , , , cord-256217-fnjer0e0 38 33 even even RB cord-256217-fnjer0e0 38 34 though though IN cord-256217-fnjer0e0 38 35 in in IN cord-256217-fnjer0e0 38 36 26 26 CD cord-256217-fnjer0e0 38 37 % % NN cord-256217-fnjer0e0 38 38 of of IN cord-256217-fnjer0e0 38 39 the the DT cord-256217-fnjer0e0 38 40 experimental experimental JJ cord-256217-fnjer0e0 38 41 animals animal NNS cord-256217-fnjer0e0 38 42 a a DT cord-256217-fnjer0e0 38 43 severe severe JJ cord-256217-fnjer0e0 38 44 and and CC cord-256217-fnjer0e0 38 45 massive massive JJ cord-256217-fnjer0e0 38 46 inflammation inflammation NN cord-256217-fnjer0e0 38 47 of of IN cord-256217-fnjer0e0 38 48 most most JJS cord-256217-fnjer0e0 38 49 ocular ocular JJ cord-256217-fnjer0e0 38 50 structures structure NNS cord-256217-fnjer0e0 38 51 was be VBD cord-256217-fnjer0e0 38 52 observed observe VBN cord-256217-fnjer0e0 38 53 . . . cord-256217-fnjer0e0 39 1 The the DT cord-256217-fnjer0e0 39 2 authors author NNS cord-256217-fnjer0e0 39 3 speculated speculate VBD cord-256217-fnjer0e0 39 4 that that IN cord-256217-fnjer0e0 39 5 gliosis gliosis NNP cord-256217-fnjer0e0 39 6 might may MD cord-256217-fnjer0e0 39 7 have have VB cord-256217-fnjer0e0 39 8 been be VBN cord-256217-fnjer0e0 39 9 present present JJ cord-256217-fnjer0e0 39 10 in in IN cord-256217-fnjer0e0 39 11 affected affected JJ cord-256217-fnjer0e0 39 12 retinas retina NNS cord-256217-fnjer0e0 39 13 as as IN cord-256217-fnjer0e0 39 14 the the DT cord-256217-fnjer0e0 39 15 result result NN cord-256217-fnjer0e0 39 16 of of IN cord-256217-fnjer0e0 39 17 breakdown breakdown NN cord-256217-fnjer0e0 39 18 of of IN cord-256217-fnjer0e0 39 19 the the DT cord-256217-fnjer0e0 39 20 blood blood NN cord-256217-fnjer0e0 39 21 - - HYPH cord-256217-fnjer0e0 39 22 ocular ocular JJ cord-256217-fnjer0e0 39 23 barrier barrier NN cord-256217-fnjer0e0 39 24 which which WDT cord-256217-fnjer0e0 39 25 can can MD cord-256217-fnjer0e0 39 26 allow allow VB cord-256217-fnjer0e0 39 27 coronavirus coronavirus NN cord-256217-fnjer0e0 39 28 - - HYPH cord-256217-fnjer0e0 39 29 bearing bear VBG cord-256217-fnjer0e0 39 30 macrophages macrophage NNS cord-256217-fnjer0e0 39 31 to to TO cord-256217-fnjer0e0 39 32 access access VB cord-256217-fnjer0e0 39 33 the the DT cord-256217-fnjer0e0 39 34 eye eye NN cord-256217-fnjer0e0 39 35 . . . cord-256217-fnjer0e0 40 1 Regarding regard VBG cord-256217-fnjer0e0 40 2 the the DT cord-256217-fnjer0e0 40 3 specific specific JJ cord-256217-fnjer0e0 40 4 vascular vascular JJ cord-256217-fnjer0e0 40 5 involvement involvement NN cord-256217-fnjer0e0 40 6 , , , cord-256217-fnjer0e0 40 7 massive massive JJ cord-256217-fnjer0e0 40 8 inflammation inflammation NN cord-256217-fnjer0e0 40 9 leads lead VBZ cord-256217-fnjer0e0 40 10 to to IN cord-256217-fnjer0e0 40 11 damage damage VB cord-256217-fnjer0e0 40 12 to to IN cord-256217-fnjer0e0 40 13 the the DT cord-256217-fnjer0e0 40 14 walls wall NNS cord-256217-fnjer0e0 40 15 of of IN cord-256217-fnjer0e0 40 16 veins vein NNS cord-256217-fnjer0e0 40 17 , , , cord-256217-fnjer0e0 40 18 evidenced evidence VBN cord-256217-fnjer0e0 40 19 by by IN cord-256217-fnjer0e0 40 20 loss loss NN cord-256217-fnjer0e0 40 21 of of IN cord-256217-fnjer0e0 40 22 continuity continuity NN cord-256217-fnjer0e0 40 23 and and CC cord-256217-fnjer0e0 40 24 erythrocytes erythrocyte VBZ cord-256217-fnjer0e0 40 25 extravasation extravasation NN cord-256217-fnjer0e0 40 26 into into IN cord-256217-fnjer0e0 40 27 the the DT cord-256217-fnjer0e0 40 28 surrounding surround VBG cord-256217-fnjer0e0 40 29 tissue tissue NN cord-256217-fnjer0e0 40 30 . . . cord-256217-fnjer0e0 41 1 Similarly similarly RB cord-256217-fnjer0e0 41 2 , , , cord-256217-fnjer0e0 41 3 the the DT cord-256217-fnjer0e0 41 4 lung lung NN cord-256217-fnjer0e0 41 5 polythrombosis polythrombosis NN cord-256217-fnjer0e0 41 6 observed observe VBD cord-256217-fnjer0e0 41 7 in in IN cord-256217-fnjer0e0 41 8 SARS SARS NNP cord-256217-fnjer0e0 41 9 - - HYPH cord-256217-fnjer0e0 41 10 COV-2 COV-2 NNP cord-256217-fnjer0e0 41 11 cases case NNS cord-256217-fnjer0e0 41 12 seems seem VBZ cord-256217-fnjer0e0 41 13 to to TO cord-256217-fnjer0e0 41 14 be be VB cord-256217-fnjer0e0 41 15 a a DT cord-256217-fnjer0e0 41 16 result result NN cord-256217-fnjer0e0 41 17 of of IN cord-256217-fnjer0e0 41 18 the the DT cord-256217-fnjer0e0 41 19 interstitial interstitial JJ cord-256217-fnjer0e0 41 20 inflammation inflammation NN cord-256217-fnjer0e0 41 21 where where WRB cord-256217-fnjer0e0 41 22 hyaline hyaline JJ cord-256217-fnjer0e0 41 23 thrombi thrombi NN cord-256217-fnjer0e0 41 24 of of IN cord-256217-fnjer0e0 41 25 the the DT cord-256217-fnjer0e0 41 26 microvessels microvessel NNS cord-256217-fnjer0e0 41 27 might may MD cord-256217-fnjer0e0 41 28 be be VB cord-256217-fnjer0e0 41 29 induced induce VBN cord-256217-fnjer0e0 41 30 by by IN cord-256217-fnjer0e0 41 31 the the DT cord-256217-fnjer0e0 41 32 perivasculitis perivasculitis NN cord-256217-fnjer0e0 41 33 affecting affect VBG cord-256217-fnjer0e0 41 34 the the DT cord-256217-fnjer0e0 41 35 vessels vessel NNS cord-256217-fnjer0e0 41 36 walls wall NNS cord-256217-fnjer0e0 41 37 embedded embed VBN cord-256217-fnjer0e0 41 38 into into IN cord-256217-fnjer0e0 41 39 the the DT cord-256217-fnjer0e0 41 40 affected affected JJ cord-256217-fnjer0e0 41 41 tissue tissue NN cord-256217-fnjer0e0 41 42 [ [ -LRB- cord-256217-fnjer0e0 41 43 11 11 CD cord-256217-fnjer0e0 41 44 ] ] -RRB- cord-256217-fnjer0e0 41 45 . . . cord-256217-fnjer0e0 42 1 At at IN cord-256217-fnjer0e0 42 2 this this DT cord-256217-fnjer0e0 42 3 stage stage NN cord-256217-fnjer0e0 42 4 , , , cord-256217-fnjer0e0 42 5 the the DT cord-256217-fnjer0e0 42 6 therapeutic therapeutic JJ cord-256217-fnjer0e0 42 7 strategy strategy NN cord-256217-fnjer0e0 42 8 is be VBZ cord-256217-fnjer0e0 42 9 still still RB cord-256217-fnjer0e0 42 10 opened open VBN cord-256217-fnjer0e0 42 11 for for IN cord-256217-fnjer0e0 42 12 discussion discussion NN cord-256217-fnjer0e0 42 13 and and CC cord-256217-fnjer0e0 42 14 might may MD cord-256217-fnjer0e0 42 15 offer offer VB cord-256217-fnjer0e0 42 16 a a DT cord-256217-fnjer0e0 42 17 series series NN cord-256217-fnjer0e0 42 18 of of IN cord-256217-fnjer0e0 42 19 fascinating fascinating JJ cord-256217-fnjer0e0 42 20 hypotheses hypothesis NNS cord-256217-fnjer0e0 42 21 for for IN cord-256217-fnjer0e0 42 22 a a DT cord-256217-fnjer0e0 42 23 rescue rescue NN cord-256217-fnjer0e0 42 24 treatment treatment NN cord-256217-fnjer0e0 42 25 in in IN cord-256217-fnjer0e0 42 26 severe severe JJ cord-256217-fnjer0e0 42 27 SARS SARS NNP cord-256217-fnjer0e0 42 28 - - HYPH cord-256217-fnjer0e0 42 29 COV-2 COV-2 NNP cord-256217-fnjer0e0 42 30 pneumonia pneumonia NN cord-256217-fnjer0e0 42 31 . . . cord-256217-fnjer0e0 43 1 Albeit albeit IN cord-256217-fnjer0e0 43 2 it -PRON- PRP cord-256217-fnjer0e0 43 3 is be VBZ cord-256217-fnjer0e0 43 4 true true JJ cord-256217-fnjer0e0 43 5 that that IN cord-256217-fnjer0e0 43 6 anti anti JJ cord-256217-fnjer0e0 43 7 - - JJ cord-256217-fnjer0e0 43 8 IL-6 il-6 JJ cord-256217-fnjer0e0 43 9 receptor receptor NN cord-256217-fnjer0e0 43 10 monoclonal monoclonal JJ cord-256217-fnjer0e0 43 11 antibody antibody NN cord-256217-fnjer0e0 43 12 has have VBZ cord-256217-fnjer0e0 43 13 given give VBN cord-256217-fnjer0e0 43 14 promising promising JJ cord-256217-fnjer0e0 43 15 results result NNS cord-256217-fnjer0e0 43 16 for for IN cord-256217-fnjer0e0 43 17 the the DT cord-256217-fnjer0e0 43 18 control control NN cord-256217-fnjer0e0 43 19 of of IN cord-256217-fnjer0e0 43 20 severe severe JJ cord-256217-fnjer0e0 43 21 SARS SARS NNP cord-256217-fnjer0e0 43 22 - - HYPH cord-256217-fnjer0e0 43 23 COV-2 COV-2 NNP cord-256217-fnjer0e0 43 24 pneumonia pneumonia NN cord-256217-fnjer0e0 44 1 , , , cord-256217-fnjer0e0 44 2 it -PRON- PRP cord-256217-fnjer0e0 44 3 is be VBZ cord-256217-fnjer0e0 44 4 interesting interesting JJ cord-256217-fnjer0e0 44 5 to to TO cord-256217-fnjer0e0 44 6 notice notice VB cord-256217-fnjer0e0 44 7 that that IN cord-256217-fnjer0e0 44 8 retinal retinal JJ cord-256217-fnjer0e0 44 9 degeneration degeneration NN cord-256217-fnjer0e0 44 10 in in IN cord-256217-fnjer0e0 44 11 ECOR ECOR NNP cord-256217-fnjer0e0 44 12 is be VBZ cord-256217-fnjer0e0 44 13 associated associate VBN cord-256217-fnjer0e0 44 14 with with IN cord-256217-fnjer0e0 44 15 an an DT cord-256217-fnjer0e0 44 16 evident evident JJ cord-256217-fnjer0e0 44 17 increase increase NN cord-256217-fnjer0e0 44 18 in in IN cord-256217-fnjer0e0 44 19 TNF TNF NNP cord-256217-fnjer0e0 44 20 - - HYPH cord-256217-fnjer0e0 44 21 alpha alpha NN cord-256217-fnjer0e0 44 22 , , , cord-256217-fnjer0e0 44 23 as as RB cord-256217-fnjer0e0 44 24 well well RB cord-256217-fnjer0e0 44 25 as as IN cord-256217-fnjer0e0 44 26 soluble soluble JJ cord-256217-fnjer0e0 44 27 TNFR2 tnfr2 NN cord-256217-fnjer0e0 44 28 , , , cord-256217-fnjer0e0 44 29 inducing induce VBG cord-256217-fnjer0e0 44 30 an an DT cord-256217-fnjer0e0 44 31 anomaly anomaly NN cord-256217-fnjer0e0 44 32 of of IN cord-256217-fnjer0e0 44 33 TNF tnf NN cord-256217-fnjer0e0 44 34 - - HYPH cord-256217-fnjer0e0 44 35 alpha alpha NN cord-256217-fnjer0e0 44 36 signaling signaling NN cord-256217-fnjer0e0 44 37 [ [ -LRB- cord-256217-fnjer0e0 44 38 12 12 CD cord-256217-fnjer0e0 44 39 ] ] -RRB- cord-256217-fnjer0e0 44 40 . . . cord-256217-fnjer0e0 45 1 The the DT cord-256217-fnjer0e0 45 2 clinical clinical JJ cord-256217-fnjer0e0 45 3 picture picture NN cord-256217-fnjer0e0 45 4 offered offer VBN cord-256217-fnjer0e0 45 5 by by IN cord-256217-fnjer0e0 45 6 SARS SARS NNP cord-256217-fnjer0e0 45 7 - - HYPH cord-256217-fnjer0e0 45 8 COV-2 COV-2 NNP cord-256217-fnjer0e0 45 9 pneumonia pneumonia NN cord-256217-fnjer0e0 45 10 seems seem VBZ cord-256217-fnjer0e0 45 11 to to TO cord-256217-fnjer0e0 45 12 present present VB cord-256217-fnjer0e0 45 13 a a DT cord-256217-fnjer0e0 45 14 series series NN cord-256217-fnjer0e0 45 15 of of IN cord-256217-fnjer0e0 45 16 similarities similarity NNS cord-256217-fnjer0e0 45 17 to to IN cord-256217-fnjer0e0 45 18 so so RB cord-256217-fnjer0e0 45 19 - - HYPH cord-256217-fnjer0e0 45 20 called call VBN cord-256217-fnjer0e0 45 21 interstitial interstitial JJ cord-256217-fnjer0e0 45 22 pneumonia pneumonia NN cord-256217-fnjer0e0 45 23 with with IN cord-256217-fnjer0e0 45 24 autoimmune autoimmune JJ cord-256217-fnjer0e0 45 25 features feature NNS cord-256217-fnjer0e0 46 1 ( ( -LRB- cord-256217-fnjer0e0 46 2 IPAF IPAF NNP cord-256217-fnjer0e0 46 3 ) ) -RRB- cord-256217-fnjer0e0 46 4 recently recently RB cord-256217-fnjer0e0 46 5 described describe VBN cord-256217-fnjer0e0 46 6 by by IN cord-256217-fnjer0e0 46 7 the the DT cord-256217-fnjer0e0 46 8 European European NNP cord-256217-fnjer0e0 46 9 Respiratory Respiratory NNP cord-256217-fnjer0e0 46 10 Society Society NNP cord-256217-fnjer0e0 46 11 and and CC cord-256217-fnjer0e0 46 12 the the DT cord-256217-fnjer0e0 46 13 American American NNP cord-256217-fnjer0e0 46 14 Thoracic Thoracic NNP cord-256217-fnjer0e0 46 15 Society Society NNP cord-256217-fnjer0e0 46 16 [ [ -LRB- cord-256217-fnjer0e0 46 17 13 13 CD cord-256217-fnjer0e0 46 18 ] ] -RRB- cord-256217-fnjer0e0 46 19 . . . cord-256217-fnjer0e0 47 1 In in IN cord-256217-fnjer0e0 47 2 IPAF IPAF NNP cord-256217-fnjer0e0 47 3 , , , cord-256217-fnjer0e0 47 4 the the DT cord-256217-fnjer0e0 47 5 immune immune JJ cord-256217-fnjer0e0 47 6 reaction reaction NN cord-256217-fnjer0e0 47 7 plays play VBZ cord-256217-fnjer0e0 47 8 a a DT cord-256217-fnjer0e0 47 9 primary primary JJ cord-256217-fnjer0e0 47 10 role role NN cord-256217-fnjer0e0 47 11 in in IN cord-256217-fnjer0e0 47 12 its -PRON- PRP$ cord-256217-fnjer0e0 47 13 pathogenesis pathogenesis NN cord-256217-fnjer0e0 47 14 . . . cord-256217-fnjer0e0 48 1 However however RB cord-256217-fnjer0e0 48 2 , , , cord-256217-fnjer0e0 48 3 there there EX cord-256217-fnjer0e0 48 4 is be VBZ cord-256217-fnjer0e0 48 5 no no DT cord-256217-fnjer0e0 48 6 general general JJ cord-256217-fnjer0e0 48 7 agreement agreement NN cord-256217-fnjer0e0 48 8 on on IN cord-256217-fnjer0e0 48 9 any any DT cord-256217-fnjer0e0 48 10 recommendations recommendation NNS cord-256217-fnjer0e0 48 11 ; ; : cord-256217-fnjer0e0 48 12 therefore therefore RB cord-256217-fnjer0e0 48 13 , , , cord-256217-fnjer0e0 48 14 even even RB cord-256217-fnjer0e0 48 15 the the DT cord-256217-fnjer0e0 48 16 diagnosis diagnosis NN cord-256217-fnjer0e0 48 17 and and CC cord-256217-fnjer0e0 48 18 management management NN cord-256217-fnjer0e0 48 19 are be VBP cord-256217-fnjer0e0 48 20 left leave VBN cord-256217-fnjer0e0 48 21 to to IN cord-256217-fnjer0e0 48 22 the the DT cord-256217-fnjer0e0 48 23 individual individual JJ cord-256217-fnjer0e0 48 24 caregiver caregiver NN cord-256217-fnjer0e0 48 25 [ [ -LRB- cord-256217-fnjer0e0 48 26 13 13 CD cord-256217-fnjer0e0 48 27 ] ] -RRB- cord-256217-fnjer0e0 48 28 . . . cord-256217-fnjer0e0 49 1 While while IN cord-256217-fnjer0e0 49 2 the the DT cord-256217-fnjer0e0 49 3 use use NN cord-256217-fnjer0e0 49 4 of of IN cord-256217-fnjer0e0 49 5 anti anti JJ cord-256217-fnjer0e0 49 6 - - JJ cord-256217-fnjer0e0 49 7 TNF tnf NN cord-256217-fnjer0e0 49 8 - - HYPH cord-256217-fnjer0e0 49 9 alpha alpha NN cord-256217-fnjer0e0 49 10 appears appear VBZ cord-256217-fnjer0e0 49 11 quite quite RB cord-256217-fnjer0e0 49 12 risky risky JJ cord-256217-fnjer0e0 49 13 due due IN cord-256217-fnjer0e0 49 14 to to IN cord-256217-fnjer0e0 49 15 the the DT cord-256217-fnjer0e0 49 16 possible possible JJ cord-256217-fnjer0e0 49 17 occurrence occurrence NN cord-256217-fnjer0e0 49 18 of of IN cord-256217-fnjer0e0 49 19 fulminant fulminant JJ cord-256217-fnjer0e0 49 20 tuberculosis tuberculosis NN cord-256217-fnjer0e0 49 21 or or CC cord-256217-fnjer0e0 49 22 might may MD cord-256217-fnjer0e0 49 23 play play VB cord-256217-fnjer0e0 49 24 a a DT cord-256217-fnjer0e0 49 25 very very RB cord-256217-fnjer0e0 49 26 limited limited JJ cord-256217-fnjer0e0 49 27 role role NN cord-256217-fnjer0e0 49 28 , , , cord-256217-fnjer0e0 49 29 other other JJ cord-256217-fnjer0e0 49 30 new new JJ cord-256217-fnjer0e0 49 31 generation generation NN cord-256217-fnjer0e0 49 32 immunosuppressives immunosuppressive NNS cord-256217-fnjer0e0 49 33 , , , cord-256217-fnjer0e0 49 34 such such JJ cord-256217-fnjer0e0 49 35 as as IN cord-256217-fnjer0e0 49 36 intravenous intravenous JJ cord-256217-fnjer0e0 49 37 immunoglobulin immunoglobulin NN cord-256217-fnjer0e0 49 38 , , , cord-256217-fnjer0e0 49 39 selective selective JJ cord-256217-fnjer0e0 49 40 IL-1 IL-1 NNP cord-256217-fnjer0e0 49 41 cytokine cytokine NN cord-256217-fnjer0e0 49 42 blockade blockade NN cord-256217-fnjer0e0 49 43 , , , cord-256217-fnjer0e0 49 44 and and CC cord-256217-fnjer0e0 49 45 JAK JAK NNP cord-256217-fnjer0e0 49 46 inhibition inhibition NN cord-256217-fnjer0e0 49 47 [ [ -LRB- cord-256217-fnjer0e0 49 48 6 6 CD cord-256217-fnjer0e0 49 49 ] ] -RRB- cord-256217-fnjer0e0 49 50 , , , cord-256217-fnjer0e0 49 51 were be VBD cord-256217-fnjer0e0 49 52 proposed propose VBN cord-256217-fnjer0e0 49 53 . . . cord-256217-fnjer0e0 50 1 However however RB cord-256217-fnjer0e0 50 2 , , , cord-256217-fnjer0e0 50 3 it -PRON- PRP cord-256217-fnjer0e0 50 4 is be VBZ cord-256217-fnjer0e0 50 5 unclear unclear JJ cord-256217-fnjer0e0 50 6 why why WRB cord-256217-fnjer0e0 50 7 the the DT cord-256217-fnjer0e0 50 8 scientific scientific JJ cord-256217-fnjer0e0 50 9 world world NN cord-256217-fnjer0e0 50 10 is be VBZ cord-256217-fnjer0e0 50 11 still still RB cord-256217-fnjer0e0 50 12 strongly strongly RB cord-256217-fnjer0e0 50 13 reluctant reluctant JJ cord-256217-fnjer0e0 50 14 to to TO cord-256217-fnjer0e0 50 15 promptly promptly RB cord-256217-fnjer0e0 50 16 use use VB cord-256217-fnjer0e0 50 17 steroids steroid NNS cord-256217-fnjer0e0 50 18 to to TO cord-256217-fnjer0e0 50 19 target target VB cord-256217-fnjer0e0 50 20 the the DT cord-256217-fnjer0e0 50 21 second second JJ cord-256217-fnjer0e0 50 22 phase phase NN cord-256217-fnjer0e0 50 23 of of IN cord-256217-fnjer0e0 50 24 the the DT cord-256217-fnjer0e0 50 25 disease disease NN cord-256217-fnjer0e0 50 26 , , , cord-256217-fnjer0e0 50 27 while while IN cord-256217-fnjer0e0 50 28 this this DT cord-256217-fnjer0e0 50 29 is be VBZ cord-256217-fnjer0e0 50 30 not not RB cord-256217-fnjer0e0 50 31 the the DT cord-256217-fnjer0e0 50 32 case case NN cord-256217-fnjer0e0 50 33 for for IN cord-256217-fnjer0e0 50 34 monoclonals monoclonal NNS cord-256217-fnjer0e0 50 35 . . . cord-256217-fnjer0e0 51 1 Similarly similarly RB cord-256217-fnjer0e0 51 2 to to IN cord-256217-fnjer0e0 51 3 Ebola Ebola NNP cord-256217-fnjer0e0 51 4 Virus Virus NNP cord-256217-fnjer0e0 51 5 Disease Disease NNP cord-256217-fnjer0e0 51 6 ( ( -LRB- cord-256217-fnjer0e0 51 7 EVD EVD NNP cord-256217-fnjer0e0 51 8 ) ) -RRB- cord-256217-fnjer0e0 51 9 , , , cord-256217-fnjer0e0 51 10 where where WRB cord-256217-fnjer0e0 51 11 steroids steroid NNS cord-256217-fnjer0e0 51 12 were be VBD cord-256217-fnjer0e0 51 13 successfully successfully RB cord-256217-fnjer0e0 51 14 used use VBN cord-256217-fnjer0e0 51 15 even even RB cord-256217-fnjer0e0 51 16 though though IN cord-256217-fnjer0e0 51 17 empirically empirically RB cord-256217-fnjer0e0 51 18 , , , cord-256217-fnjer0e0 51 19 the the DT cord-256217-fnjer0e0 51 20 number number NN cord-256217-fnjer0e0 51 21 of of IN cord-256217-fnjer0e0 51 22 circulating circulate VBG cord-256217-fnjer0e0 51 23 T t NN cord-256217-fnjer0e0 51 24 lymphocytes lymphocyte NNS cord-256217-fnjer0e0 51 25 is be VBZ cord-256217-fnjer0e0 51 26 dramatically dramatically RB cord-256217-fnjer0e0 51 27 reduced reduce VBN cord-256217-fnjer0e0 51 28 in in IN cord-256217-fnjer0e0 51 29 severe severe JJ cord-256217-fnjer0e0 51 30 cases case NNS cord-256217-fnjer0e0 51 31 , , , cord-256217-fnjer0e0 51 32 and and CC cord-256217-fnjer0e0 51 33 elevated elevated JJ cord-256217-fnjer0e0 51 34 cytokine cytokine NN cord-256217-fnjer0e0 51 35 levels level NNS cord-256217-fnjer0e0 51 36 in in IN cord-256217-fnjer0e0 51 37 the the DT cord-256217-fnjer0e0 51 38 serum serum NN cord-256217-fnjer0e0 51 39 are be VBP cord-256217-fnjer0e0 51 40 observed observe VBN cord-256217-fnjer0e0 51 41 [ [ -LRB- cord-256217-fnjer0e0 51 42 14 14 CD cord-256217-fnjer0e0 51 43 ] ] -RRB- cord-256217-fnjer0e0 51 44 . . . cord-256217-fnjer0e0 52 1 Under under IN cord-256217-fnjer0e0 52 2 that that DT cord-256217-fnjer0e0 52 3 light light NN cord-256217-fnjer0e0 52 4 , , , cord-256217-fnjer0e0 52 5 steroids steroid NNS cord-256217-fnjer0e0 52 6 might may MD cord-256217-fnjer0e0 52 7 appear appear VB cord-256217-fnjer0e0 52 8 a a DT cord-256217-fnjer0e0 52 9 potent potent JJ cord-256217-fnjer0e0 52 10 weapon weapon NN cord-256217-fnjer0e0 52 11 against against IN cord-256217-fnjer0e0 52 12 fatal fatal JJ cord-256217-fnjer0e0 52 13 immune immune JJ cord-256217-fnjer0e0 52 14 system system NN cord-256217-fnjer0e0 52 15 activation activation NN cord-256217-fnjer0e0 52 16 . . . cord-256217-fnjer0e0 53 1 Since since IN cord-256217-fnjer0e0 53 2 World World NNP cord-256217-fnjer0e0 53 3 Health Health NNP cord-256217-fnjer0e0 53 4 Organization Organization NNP cord-256217-fnjer0e0 53 5 provided provide VBD cord-256217-fnjer0e0 53 6 no no DT cord-256217-fnjer0e0 53 7 guideline guideline NN cord-256217-fnjer0e0 53 8 on on IN cord-256217-fnjer0e0 53 9 corticosteroids corticosteroid NNS cord-256217-fnjer0e0 53 10 use use VBP cord-256217-fnjer0e0 53 11 for for IN cord-256217-fnjer0e0 53 12 the the DT cord-256217-fnjer0e0 53 13 management management NN cord-256217-fnjer0e0 53 14 of of IN cord-256217-fnjer0e0 53 15 SARS SARS NNP cord-256217-fnjer0e0 53 16 - - HYPH cord-256217-fnjer0e0 53 17 COV-2 COV-2 NNP cord-256217-fnjer0e0 53 18 , , , cord-256217-fnjer0e0 53 19 they -PRON- PRP cord-256217-fnjer0e0 53 20 can can MD cord-256217-fnjer0e0 53 21 be be VB cord-256217-fnjer0e0 53 22 only only RB cord-256217-fnjer0e0 53 23 used use VBN cord-256217-fnjer0e0 53 24 empirically empirically RB cord-256217-fnjer0e0 53 25 with with IN cord-256217-fnjer0e0 53 26 no no DT cord-256217-fnjer0e0 53 27 indication indication NN cord-256217-fnjer0e0 53 28 on on IN cord-256217-fnjer0e0 53 29 timing timing NN cord-256217-fnjer0e0 53 30 , , , cord-256217-fnjer0e0 53 31 duration duration NN cord-256217-fnjer0e0 53 32 , , , cord-256217-fnjer0e0 53 33 and and CC cord-256217-fnjer0e0 53 34 dosage dosage NN cord-256217-fnjer0e0 53 35 . . . cord-256217-fnjer0e0 54 1 In in IN cord-256217-fnjer0e0 54 2 addition addition NN cord-256217-fnjer0e0 54 3 , , , cord-256217-fnjer0e0 54 4 early early JJ cord-256217-fnjer0e0 54 5 use use NN cord-256217-fnjer0e0 54 6 of of IN cord-256217-fnjer0e0 54 7 steroids steroid NNS cord-256217-fnjer0e0 54 8 seems seem VBZ cord-256217-fnjer0e0 54 9 to to TO cord-256217-fnjer0e0 54 10 exert exert VB cord-256217-fnjer0e0 54 11 a a DT cord-256217-fnjer0e0 54 12 more more RBR cord-256217-fnjer0e0 54 13 than than IN cord-256217-fnjer0e0 54 14 promising promising JJ cord-256217-fnjer0e0 54 15 control control NN cord-256217-fnjer0e0 54 16 of of IN cord-256217-fnjer0e0 54 17 inflammatory inflammatory JJ cord-256217-fnjer0e0 54 18 response response NN cord-256217-fnjer0e0 54 19 in in IN cord-256217-fnjer0e0 54 20 other other JJ cord-256217-fnjer0e0 54 21 severe severe JJ cord-256217-fnjer0e0 54 22 viral viral JJ cord-256217-fnjer0e0 54 23 diseases disease NNS cord-256217-fnjer0e0 54 24 [ [ -LRB- cord-256217-fnjer0e0 54 25 14 14 CD cord-256217-fnjer0e0 54 26 ] ] -RRB- cord-256217-fnjer0e0 54 27 . . . cord-256217-fnjer0e0 55 1 The the DT cord-256217-fnjer0e0 55 2 same same JJ cord-256217-fnjer0e0 55 3 issue issue NN cord-256217-fnjer0e0 55 4 was be VBD cord-256217-fnjer0e0 55 5 addressed address VBN cord-256217-fnjer0e0 55 6 several several JJ cord-256217-fnjer0e0 55 7 times time NNS cord-256217-fnjer0e0 55 8 for for IN cord-256217-fnjer0e0 55 9 more more JJR cord-256217-fnjer0e0 55 10 common common JJ cord-256217-fnjer0e0 55 11 diseases disease NNS cord-256217-fnjer0e0 55 12 like like IN cord-256217-fnjer0e0 55 13 herpes herpes NN cord-256217-fnjer0e0 55 14 virus virus NN cord-256217-fnjer0e0 55 15 encephalitis encephalitis JJ cord-256217-fnjer0e0 55 16 [ [ -LRB- cord-256217-fnjer0e0 55 17 15 15 CD cord-256217-fnjer0e0 55 18 ] ] -RRB- cord-256217-fnjer0e0 55 19 , , , cord-256217-fnjer0e0 55 20 which which WDT cord-256217-fnjer0e0 55 21 is be VBZ cord-256217-fnjer0e0 55 22 universally universally RB cord-256217-fnjer0e0 55 23 recognized recognize VBN cord-256217-fnjer0e0 55 24 as as IN cord-256217-fnjer0e0 55 25 a a DT cord-256217-fnjer0e0 55 26 postviral postviral JJ cord-256217-fnjer0e0 55 27 autoimmune autoimmune JJ cord-256217-fnjer0e0 55 28 response response NN cord-256217-fnjer0e0 55 29 . . . cord-256217-fnjer0e0 56 1 Herpetic herpetic JJ cord-256217-fnjer0e0 56 2 postviral postviral NN cord-256217-fnjer0e0 56 3 central central JJ cord-256217-fnjer0e0 56 4 nervous nervous JJ cord-256217-fnjer0e0 56 5 system system NN cord-256217-fnjer0e0 56 6 inflammation inflammation NN cord-256217-fnjer0e0 56 7 has have VBZ cord-256217-fnjer0e0 56 8 corticosteroids corticosteroid NNS cord-256217-fnjer0e0 56 9 as as IN cord-256217-fnjer0e0 56 10 the the DT cord-256217-fnjer0e0 56 11 first first JJ cord-256217-fnjer0e0 56 12 line line NN cord-256217-fnjer0e0 56 13 drug drug NN cord-256217-fnjer0e0 56 14 in in IN cord-256217-fnjer0e0 56 15 the the DT cord-256217-fnjer0e0 56 16 therapeutic therapeutic JJ cord-256217-fnjer0e0 56 17 armamentarium armamentarium NN cord-256217-fnjer0e0 56 18 [ [ -LRB- cord-256217-fnjer0e0 56 19 16 16 CD cord-256217-fnjer0e0 56 20 ] ] -RRB- cord-256217-fnjer0e0 56 21 and and CC cord-256217-fnjer0e0 56 22 might may MD cord-256217-fnjer0e0 56 23 be be VB cord-256217-fnjer0e0 56 24 considered consider VBN cord-256217-fnjer0e0 56 25 a a DT cord-256217-fnjer0e0 56 26 possible possible JJ cord-256217-fnjer0e0 56 27 model model NN cord-256217-fnjer0e0 56 28 for for IN cord-256217-fnjer0e0 56 29 a a DT cord-256217-fnjer0e0 56 30 prompt prompt JJ cord-256217-fnjer0e0 56 31 response response NN cord-256217-fnjer0e0 56 32 in in IN cord-256217-fnjer0e0 56 33 treating treat VBG cord-256217-fnjer0e0 56 34 earlier early JJR cord-256217-fnjer0e0 56 35 life life NN cord-256217-fnjer0e0 56 36 - - HYPH cord-256217-fnjer0e0 56 37 threatening threaten VBG cord-256217-fnjer0e0 56 38 forms form NNS cord-256217-fnjer0e0 56 39 of of IN cord-256217-fnjer0e0 56 40 SARS SARS NNP cord-256217-fnjer0e0 56 41 - - HYPH cord-256217-fnjer0e0 56 42 COV-2 COV-2 NNP cord-256217-fnjer0e0 56 43 . . . cord-256217-fnjer0e0 57 1 On on IN cord-256217-fnjer0e0 57 2 the the DT cord-256217-fnjer0e0 57 3 basis basis NN cord-256217-fnjer0e0 57 4 of of IN cord-256217-fnjer0e0 57 5 the the DT cord-256217-fnjer0e0 57 6 current current JJ cord-256217-fnjer0e0 57 7 knowledge knowledge NN cord-256217-fnjer0e0 57 8 , , , cord-256217-fnjer0e0 57 9 corticosteroids corticosteroid NNS cord-256217-fnjer0e0 57 10 might may MD cord-256217-fnjer0e0 57 11 be be VB cord-256217-fnjer0e0 57 12 a a DT cord-256217-fnjer0e0 57 13 potent potent JJ cord-256217-fnjer0e0 57 14 therapeutic therapeutic JJ cord-256217-fnjer0e0 57 15 weapon weapon NN cord-256217-fnjer0e0 57 16 for for IN cord-256217-fnjer0e0 57 17 the the DT cord-256217-fnjer0e0 57 18 second second JJ cord-256217-fnjer0e0 57 19 phase phase NN cord-256217-fnjer0e0 57 20 of of IN cord-256217-fnjer0e0 57 21 the the DT cord-256217-fnjer0e0 57 22 disease disease NN cord-256217-fnjer0e0 57 23 , , , cord-256217-fnjer0e0 57 24 when when WRB cord-256217-fnjer0e0 57 25 the the DT cord-256217-fnjer0e0 57 26 immune immune JJ cord-256217-fnjer0e0 57 27 system system NN cord-256217-fnjer0e0 57 28 targets target VBZ cord-256217-fnjer0e0 57 29 dramatically dramatically RB cord-256217-fnjer0e0 57 30 multiple multiple JJ cord-256217-fnjer0e0 57 31 organs organ NNS cord-256217-fnjer0e0 57 32 and and CC cord-256217-fnjer0e0 57 33 specifically specifically RB cord-256217-fnjer0e0 57 34 the the DT cord-256217-fnjer0e0 57 35 lungs lung NNS cord-256217-fnjer0e0 57 36 , , , cord-256217-fnjer0e0 57 37 while while IN cord-256217-fnjer0e0 57 38 it -PRON- PRP cord-256217-fnjer0e0 57 39 has have VBZ cord-256217-fnjer0e0 57 40 to to TO cord-256217-fnjer0e0 57 41 be be VB cord-256217-fnjer0e0 57 42 kept keep VBN cord-256217-fnjer0e0 57 43 in in IN cord-256217-fnjer0e0 57 44 mind mind NN cord-256217-fnjer0e0 57 45 that that IN cord-256217-fnjer0e0 57 46 their -PRON- PRP$ cord-256217-fnjer0e0 57 47 use use NN cord-256217-fnjer0e0 57 48 can can MD cord-256217-fnjer0e0 57 49 be be VB cord-256217-fnjer0e0 57 50 risky risky JJ cord-256217-fnjer0e0 57 51 when when WRB cord-256217-fnjer0e0 57 52 the the DT cord-256217-fnjer0e0 57 53 activation activation NN cord-256217-fnjer0e0 57 54 of of IN cord-256217-fnjer0e0 57 55 inflammatory inflammatory JJ cord-256217-fnjer0e0 57 56 processes process NNS cord-256217-fnjer0e0 57 57 remains remain VBZ cord-256217-fnjer0e0 57 58 within within IN cord-256217-fnjer0e0 57 59 the the DT cord-256217-fnjer0e0 57 60 normal normal JJ cord-256217-fnjer0e0 57 61 range range NN cord-256217-fnjer0e0 57 62 . . . cord-256217-fnjer0e0 58 1 However however RB cord-256217-fnjer0e0 58 2 , , , cord-256217-fnjer0e0 58 3 the the DT cord-256217-fnjer0e0 58 4 risk risk NN cord-256217-fnjer0e0 58 5 / / SYM cord-256217-fnjer0e0 58 6 benefit benefit NN cord-256217-fnjer0e0 58 7 ratio ratio NN cord-256217-fnjer0e0 58 8 of of IN cord-256217-fnjer0e0 58 9 corticosteroids corticosteroid NNS cord-256217-fnjer0e0 58 10 for for IN cord-256217-fnjer0e0 58 11 severe severe JJ cord-256217-fnjer0e0 58 12 form form NN cord-256217-fnjer0e0 58 13 of of IN cord-256217-fnjer0e0 58 14 SARS SARS NNP cord-256217-fnjer0e0 58 15 - - HYPH cord-256217-fnjer0e0 58 16 COV-2 COV-2 NNP cord-256217-fnjer0e0 58 17 disease disease NN cord-256217-fnjer0e0 58 18 should should MD cord-256217-fnjer0e0 58 19 be be VB cord-256217-fnjer0e0 58 20 clarified clarify VBN cord-256217-fnjer0e0 58 21 by by IN cord-256217-fnjer0e0 58 22 the the DT cord-256217-fnjer0e0 58 23 health health NN cord-256217-fnjer0e0 58 24 authorities authority NNS cord-256217-fnjer0e0 58 25 [ [ -LRB- cord-256217-fnjer0e0 58 26 17 17 CD cord-256217-fnjer0e0 58 27 ] ] -RRB- cord-256217-fnjer0e0 58 28 , , , cord-256217-fnjer0e0 58 29 as as RB cord-256217-fnjer0e0 58 30 well well RB cord-256217-fnjer0e0 58 31 as as IN cord-256217-fnjer0e0 58 32 the the DT cord-256217-fnjer0e0 58 33 weight weight NN cord-256217-fnjer0e0 58 34 of of IN cord-256217-fnjer0e0 58 35 cost cost NN cord-256217-fnjer0e0 58 36 - - HYPH cord-256217-fnjer0e0 58 37 effectiveness effectiveness NN cord-256217-fnjer0e0 58 38 compared compare VBN cord-256217-fnjer0e0 58 39 to to IN cord-256217-fnjer0e0 58 40 other other JJ cord-256217-fnjer0e0 58 41 therapies therapy NNS cord-256217-fnjer0e0 58 42 like like IN cord-256217-fnjer0e0 58 43 monoclonals monoclonal NNS cord-256217-fnjer0e0 58 44 . . . cord-256217-fnjer0e0 59 1 Moreover moreover RB cord-256217-fnjer0e0 59 2 , , , cord-256217-fnjer0e0 59 3 the the DT cord-256217-fnjer0e0 59 4 SARS SARS NNP cord-256217-fnjer0e0 59 5 - - HYPH cord-256217-fnjer0e0 59 6 COV-2 COV-2 NNP cord-256217-fnjer0e0 59 7 pneumonia pneumonia NN cord-256217-fnjer0e0 59 8 animal animal NN cord-256217-fnjer0e0 59 9 model model NN cord-256217-fnjer0e0 59 10 described describe VBN cord-256217-fnjer0e0 59 11 in in IN cord-256217-fnjer0e0 59 12 2010 2010 CD cord-256217-fnjer0e0 59 13 by by IN cord-256217-fnjer0e0 59 14 Smits Smits NNP cord-256217-fnjer0e0 59 15 et et NNP cord-256217-fnjer0e0 59 16 al al NNP cord-256217-fnjer0e0 59 17 . . . cord-256217-fnjer0e0 60 1 [ [ -LRB- cord-256217-fnjer0e0 60 2 18 18 CD cord-256217-fnjer0e0 60 3 ] ] -RRB- cord-256217-fnjer0e0 60 4 presents present VBZ cord-256217-fnjer0e0 60 5 many many JJ cord-256217-fnjer0e0 60 6 similarities similarity NNS cord-256217-fnjer0e0 60 7 with with IN cord-256217-fnjer0e0 60 8 ECOR ECOR NNP cord-256217-fnjer0e0 60 9 reported report VBD cord-256217-fnjer0e0 60 10 almost almost RB cord-256217-fnjer0e0 60 11 2 2 CD cord-256217-fnjer0e0 60 12 decades decade NNS cord-256217-fnjer0e0 60 13 earlier early RBR cord-256217-fnjer0e0 60 14 , , , cord-256217-fnjer0e0 60 15 in in IN cord-256217-fnjer0e0 60 16 terms term NNS cord-256217-fnjer0e0 60 17 of of IN cord-256217-fnjer0e0 60 18 viral viral JJ cord-256217-fnjer0e0 60 19 clearance clearance NN cord-256217-fnjer0e0 60 20 and and CC cord-256217-fnjer0e0 60 21 timing timing NN cord-256217-fnjer0e0 60 22 of of IN cord-256217-fnjer0e0 60 23 immune immune JJ cord-256217-fnjer0e0 60 24 response response NN cord-256217-fnjer0e0 60 25 . . . cord-256217-fnjer0e0 61 1 Considering consider VBG cord-256217-fnjer0e0 61 2 the the DT cord-256217-fnjer0e0 61 3 course course NN cord-256217-fnjer0e0 61 4 of of IN cord-256217-fnjer0e0 61 5 the the DT cord-256217-fnjer0e0 61 6 disease disease NN cord-256217-fnjer0e0 61 7 , , , cord-256217-fnjer0e0 61 8 it -PRON- PRP cord-256217-fnjer0e0 61 9 seems seem VBZ cord-256217-fnjer0e0 61 10 the the DT cord-256217-fnjer0e0 61 11 supposed suppose VBN cord-256217-fnjer0e0 61 12 postcoronavirus postcoronavirus NNP cord-256217-fnjer0e0 61 13 immune immune NNP cord-256217-fnjer0e0 61 14 response response NN cord-256217-fnjer0e0 61 15 happens happen VBZ cord-256217-fnjer0e0 61 16 within within IN cord-256217-fnjer0e0 61 17 10 10 CD cord-256217-fnjer0e0 61 18 to to TO cord-256217-fnjer0e0 61 19 14 14 CD cord-256217-fnjer0e0 61 20 days day NNS cord-256217-fnjer0e0 61 21 after after IN cord-256217-fnjer0e0 61 22 the the DT cord-256217-fnjer0e0 61 23 onset onset NN cord-256217-fnjer0e0 61 24 of of IN cord-256217-fnjer0e0 61 25 the the DT cord-256217-fnjer0e0 61 26 disease disease NN cord-256217-fnjer0e0 61 27 in in IN cord-256217-fnjer0e0 61 28 both both DT cord-256217-fnjer0e0 61 29 models model NNS cord-256217-fnjer0e0 61 30 . . . cord-256217-fnjer0e0 62 1 Consequently consequently RB cord-256217-fnjer0e0 62 2 , , , cord-256217-fnjer0e0 62 3 that that DT cord-256217-fnjer0e0 62 4 might may MD cord-256217-fnjer0e0 62 5 be be VB cord-256217-fnjer0e0 62 6 the the DT cord-256217-fnjer0e0 62 7 appropriate appropriate JJ cord-256217-fnjer0e0 62 8 timing timing NN cord-256217-fnjer0e0 62 9 to to TO cord-256217-fnjer0e0 62 10 treat treat VB cord-256217-fnjer0e0 62 11 , , , cord-256217-fnjer0e0 62 12 while while IN cord-256217-fnjer0e0 62 13 the the DT cord-256217-fnjer0e0 62 14 viral viral JJ cord-256217-fnjer0e0 62 15 insult insult NN cord-256217-fnjer0e0 62 16 might may MD cord-256217-fnjer0e0 62 17 be be VB cord-256217-fnjer0e0 62 18 over over RB cord-256217-fnjer0e0 62 19 already already RB cord-256217-fnjer0e0 62 20 as as IN cord-256217-fnjer0e0 62 21 per per IN cord-256217-fnjer0e0 62 22 the the DT cord-256217-fnjer0e0 62 23 animal animal NN cord-256217-fnjer0e0 62 24 model model NN cord-256217-fnjer0e0 62 25 . . . cord-256217-fnjer0e0 63 1 At at IN cord-256217-fnjer0e0 63 2 that that DT cord-256217-fnjer0e0 63 3 time time NN cord-256217-fnjer0e0 63 4 , , , cord-256217-fnjer0e0 63 5 a a DT cord-256217-fnjer0e0 63 6 prompt prompt JJ cord-256217-fnjer0e0 63 7 intervention intervention NN cord-256217-fnjer0e0 63 8 with with IN cord-256217-fnjer0e0 63 9 no no DT cord-256217-fnjer0e0 63 10 delay delay NN cord-256217-fnjer0e0 63 11 either either CC cord-256217-fnjer0e0 63 12 by by IN cord-256217-fnjer0e0 63 13 monoclonals monoclonal NNS cord-256217-fnjer0e0 63 14 or or CC cord-256217-fnjer0e0 63 15 by by IN cord-256217-fnjer0e0 63 16 steroids steroid NNS cord-256217-fnjer0e0 63 17 may may MD cord-256217-fnjer0e0 63 18 rescue rescue VB cord-256217-fnjer0e0 63 19 the the DT cord-256217-fnjer0e0 63 20 patient patient NN cord-256217-fnjer0e0 63 21 and and CC cord-256217-fnjer0e0 63 22 avoid avoid VB cord-256217-fnjer0e0 63 23 the the DT cord-256217-fnjer0e0 63 24 local local JJ cord-256217-fnjer0e0 63 25 immune immune NN cord-256217-fnjer0e0 63 26 - - HYPH cord-256217-fnjer0e0 63 27 driven drive VBN cord-256217-fnjer0e0 63 28 irreversible irreversible JJ cord-256217-fnjer0e0 63 29 tissue tissue NN cord-256217-fnjer0e0 63 30 damage damage NN cord-256217-fnjer0e0 63 31 . . . cord-256217-fnjer0e0 64 1 It -PRON- PRP cord-256217-fnjer0e0 64 2 might may MD cord-256217-fnjer0e0 64 3 have have VB cord-256217-fnjer0e0 64 4 been be VBN cord-256217-fnjer0e0 64 5 appropriate appropriate JJ cord-256217-fnjer0e0 64 6 to to TO cord-256217-fnjer0e0 64 7 test test VB cord-256217-fnjer0e0 64 8 these these DT cord-256217-fnjer0e0 64 9 hypotheses hypothesis NNS cord-256217-fnjer0e0 64 10 by by IN cord-256217-fnjer0e0 64 11 an an DT cord-256217-fnjer0e0 64 12 appropriate appropriate JJ cord-256217-fnjer0e0 64 13 trial trial NN cord-256217-fnjer0e0 64 14 , , , cord-256217-fnjer0e0 64 15 but but CC cord-256217-fnjer0e0 64 16 nowadays nowadays RB cord-256217-fnjer0e0 64 17 time time NN cord-256217-fnjer0e0 64 18 does do VBZ cord-256217-fnjer0e0 64 19 not not RB cord-256217-fnjer0e0 64 20 play play VB cord-256217-fnjer0e0 64 21 in in IN cord-256217-fnjer0e0 64 22 favor favor NN cord-256217-fnjer0e0 65 1 and and CC cord-256217-fnjer0e0 65 2 there there EX cord-256217-fnjer0e0 65 3 is be VBZ cord-256217-fnjer0e0 65 4 the the DT cord-256217-fnjer0e0 65 5 urgent urgent JJ cord-256217-fnjer0e0 65 6 need need NN cord-256217-fnjer0e0 65 7 of of IN cord-256217-fnjer0e0 65 8 a a DT cord-256217-fnjer0e0 65 9 prompt prompt JJ cord-256217-fnjer0e0 65 10 and and CC cord-256217-fnjer0e0 65 11 brave brave JJ cord-256217-fnjer0e0 65 12 action action NN cord-256217-fnjer0e0 65 13 . . . cord-256217-fnjer0e0 66 1 Can Can MD cord-256217-fnjer0e0 66 2 the the DT cord-256217-fnjer0e0 66 3 coronavirus coronavirus NN cord-256217-fnjer0e0 66 4 disease disease NN cord-256217-fnjer0e0 66 5 2019 2019 CD cord-256217-fnjer0e0 66 6 ( ( -LRB- cord-256217-fnjer0e0 66 7 COVID-19 COVID-19 NNP cord-256217-fnjer0e0 66 8 ) ) -RRB- cord-256217-fnjer0e0 66 9 affect affect VB cord-256217-fnjer0e0 66 10 the the DT cord-256217-fnjer0e0 66 11 eyes eye NNS cord-256217-fnjer0e0 66 12 ? ? . cord-256217-fnjer0e0 67 1 A a DT cord-256217-fnjer0e0 67 2 review review NN cord-256217-fnjer0e0 67 3 of of IN cord-256217-fnjer0e0 67 4 coronaviruses coronaviruse NNS cord-256217-fnjer0e0 67 5 and and CC cord-256217-fnjer0e0 67 6 ocular ocular JJ cord-256217-fnjer0e0 67 7 implications implication NNS cord-256217-fnjer0e0 67 8 in in IN cord-256217-fnjer0e0 67 9 humans human NNS cord-256217-fnjer0e0 67 10 and and CC cord-256217-fnjer0e0 67 11 animals animal NNS cord-256217-fnjer0e0 68 1 WHO who WP cord-256217-fnjer0e0 68 2 ( ( -LRB- cord-256217-fnjer0e0 68 3 2020 2020 CD cord-256217-fnjer0e0 68 4 ) ) -RRB- cord-256217-fnjer0e0 69 1 WHO who WP cord-256217-fnjer0e0 69 2 director director NN cord-256217-fnjer0e0 69 3 - - HYPH cord-256217-fnjer0e0 69 4 general general NNP cord-256217-fnjer0e0 69 5 's 's POS cord-256217-fnjer0e0 69 6 opening opening NN cord-256217-fnjer0e0 69 7 remarks remark NNS cord-256217-fnjer0e0 69 8 at at IN cord-256217-fnjer0e0 69 9 the the DT cord-256217-fnjer0e0 69 10 media medium NNS cord-256217-fnjer0e0 69 11 briefing briefing NN cord-256217-fnjer0e0 69 12 on on IN cord-256217-fnjer0e0 69 13 COVID-19 COVID-19 NNP cord-256217-fnjer0e0 69 14 - - HYPH cord-256217-fnjer0e0 69 15 11 11 CD cord-256217-fnjer0e0 69 16 WHO WHO NNP cord-256217-fnjer0e0 69 17 ( ( -LRB- cord-256217-fnjer0e0 69 18 2020 2020 CD cord-256217-fnjer0e0 69 19 ) ) -RRB- cord-256217-fnjer0e0 70 1 Coronavirus Coronavirus NNP cord-256217-fnjer0e0 70 2 disease disease NN cord-256217-fnjer0e0 70 3 2019 2019 CD cord-256217-fnjer0e0 70 4 ( ( -LRB- cord-256217-fnjer0e0 70 5 COVID-19 COVID-19 NNP cord-256217-fnjer0e0 70 6 ) ) -RRB- cord-256217-fnjer0e0 70 7 situation situation NN cord-256217-fnjer0e0 70 8 report-81 report-81 NNP cord-256217-fnjer0e0 70 9 Chloroquine Chloroquine NNP cord-256217-fnjer0e0 70 10 and and CC cord-256217-fnjer0e0 70 11 hydroxychloroquine hydroxychloroquine NN cord-256217-fnjer0e0 70 12 as as IN cord-256217-fnjer0e0 70 13 available available JJ cord-256217-fnjer0e0 70 14 weapons weapon NNS cord-256217-fnjer0e0 70 15 to to TO cord-256217-fnjer0e0 70 16 fight fight VB cord-256217-fnjer0e0 70 17 COVID-19 COVID-19 NNP cord-256217-fnjer0e0 70 18 World World NNP cord-256217-fnjer0e0 70 19 Health Health NNP cord-256217-fnjer0e0 70 20 Organization Organization NNP cord-256217-fnjer0e0 70 21 declares declare VBZ cord-256217-fnjer0e0 70 22 global global JJ cord-256217-fnjer0e0 70 23 emergency emergency NN cord-256217-fnjer0e0 70 24 : : : cord-256217-fnjer0e0 70 25 a a DT cord-256217-fnjer0e0 70 26 review review NN cord-256217-fnjer0e0 70 27 of of IN cord-256217-fnjer0e0 70 28 the the DT cord-256217-fnjer0e0 70 29 2019 2019 CD cord-256217-fnjer0e0 70 30 novel novel NN cord-256217-fnjer0e0 70 31 coronavirus coronavirus NN cord-256217-fnjer0e0 70 32 ( ( -LRB- cord-256217-fnjer0e0 70 33 COVID-19 COVID-19 NNP cord-256217-fnjer0e0 70 34 ) ) -RRB- cord-256217-fnjer0e0 70 35 HLH HLH NNP cord-256217-fnjer0e0 70 36 across across IN cord-256217-fnjer0e0 70 37 speciality speciality NN cord-256217-fnjer0e0 70 38 collaboration collaboration NN cord-256217-fnjer0e0 70 39 , , , cord-256217-fnjer0e0 70 40 UK UK NNP cord-256217-fnjer0e0 70 41 COVID-19 COVID-19 NNP cord-256217-fnjer0e0 70 42 : : : cord-256217-fnjer0e0 70 43 consider consider VB cord-256217-fnjer0e0 70 44 cytokine cytokine JJ cord-256217-fnjer0e0 70 45 storm storm NN cord-256217-fnjer0e0 70 46 syndromes syndrome NNS cord-256217-fnjer0e0 70 47 and and CC cord-256217-fnjer0e0 70 48 immunosuppression immunosuppression NN cord-256217-fnjer0e0 71 1 The the DT cord-256217-fnjer0e0 71 2 cytokine cytokine NN cord-256217-fnjer0e0 71 3 release release NN cord-256217-fnjer0e0 71 4 syndrome syndrome NN cord-256217-fnjer0e0 71 5 ( ( -LRB- cord-256217-fnjer0e0 71 6 CRS CRS NNP cord-256217-fnjer0e0 71 7 ) ) -RRB- cord-256217-fnjer0e0 71 8 of of IN cord-256217-fnjer0e0 71 9 severe severe JJ cord-256217-fnjer0e0 71 10 COVID-19 covid-19 NN cord-256217-fnjer0e0 71 11 and and CC cord-256217-fnjer0e0 71 12 Interleukin-6 Interleukin-6 NNP cord-256217-fnjer0e0 72 1 receptor receptor NN cord-256217-fnjer0e0 72 2 ( ( -LRB- cord-256217-fnjer0e0 72 3 IL-6R IL-6R NNP cord-256217-fnjer0e0 72 4 ) ) -RRB- cord-256217-fnjer0e0 72 5 antagonist antagonist NN cord-256217-fnjer0e0 73 1 Tocilizumab Tocilizumab NNP cord-256217-fnjer0e0 73 2 may may MD cord-256217-fnjer0e0 73 3 be be VB cord-256217-fnjer0e0 73 4 the the DT cord-256217-fnjer0e0 73 5 key key NN cord-256217-fnjer0e0 73 6 to to TO cord-256217-fnjer0e0 73 7 reduce reduce VB cord-256217-fnjer0e0 73 8 the the DT cord-256217-fnjer0e0 73 9 mortality mortality NN cord-256217-fnjer0e0 73 10 Retinopathy retinopathy NN cord-256217-fnjer0e0 73 11 following follow VBG cord-256217-fnjer0e0 73 12 intravitreal intravitreal NN cord-256217-fnjer0e0 73 13 injection injection NN cord-256217-fnjer0e0 73 14 of of IN cord-256217-fnjer0e0 73 15 mice mouse NNS cord-256217-fnjer0e0 73 16 with with IN cord-256217-fnjer0e0 73 17 MHV MHV NNP cord-256217-fnjer0e0 73 18 strain strain NN cord-256217-fnjer0e0 73 19 JHM JHM NNP cord-256217-fnjer0e0 73 20 Ocular ocular JJ cord-256217-fnjer0e0 73 21 tropisms tropism NNS cord-256217-fnjer0e0 73 22 of of IN cord-256217-fnjer0e0 73 23 murine murine JJ cord-256217-fnjer0e0 73 24 coronavirus coronavirus NN cord-256217-fnjer0e0 73 25 ( ( -LRB- cord-256217-fnjer0e0 73 26 strain strain NN cord-256217-fnjer0e0 73 27 JHM JHM NNP cord-256217-fnjer0e0 73 28 ) ) -RRB- cord-256217-fnjer0e0 73 29 after after IN cord-256217-fnjer0e0 73 30 inoculation inoculation NN cord-256217-fnjer0e0 73 31 by by IN cord-256217-fnjer0e0 73 32 various various JJ cord-256217-fnjer0e0 73 33 routes route NNS cord-256217-fnjer0e0 74 1 Guillain Guillain NNP cord-256217-fnjer0e0 74 2 - - HYPH cord-256217-fnjer0e0 74 3 Barré Barré NNP cord-256217-fnjer0e0 74 4 syndrome syndrome NN cord-256217-fnjer0e0 74 5 associated associate VBN cord-256217-fnjer0e0 74 6 with with IN cord-256217-fnjer0e0 74 7 SARS SARS NNP cord-256217-fnjer0e0 74 8 - - HYPH cord-256217-fnjer0e0 74 9 CoV-2 CoV-2 NNP cord-256217-fnjer0e0 74 10 infection infection NN cord-256217-fnjer0e0 74 11 : : : cord-256217-fnjer0e0 74 12 causality causality NN cord-256217-fnjer0e0 74 13 or or CC cord-256217-fnjer0e0 74 14 coincidence coincidence NN cord-256217-fnjer0e0 74 15 ? ? . cord-256217-fnjer0e0 75 1 A a DT cord-256217-fnjer0e0 75 2 pathological pathological JJ cord-256217-fnjer0e0 75 3 report report NN cord-256217-fnjer0e0 75 4 of of IN cord-256217-fnjer0e0 75 5 three three CD cord-256217-fnjer0e0 75 6 COVID-19 covid-19 CD cord-256217-fnjer0e0 75 7 cases case NNS cord-256217-fnjer0e0 75 8 by by IN cord-256217-fnjer0e0 75 9 minimally minimally RB cord-256217-fnjer0e0 75 10 invasive invasive JJ cord-256217-fnjer0e0 75 11 autopsies autopsy NNS cord-256217-fnjer0e0 75 12 Retinal retinal JJ cord-256217-fnjer0e0 75 13 degeneration degeneration NN cord-256217-fnjer0e0 75 14 in in IN cord-256217-fnjer0e0 75 15 experimental experimental JJ cord-256217-fnjer0e0 75 16 coronavirus coronavirus NN cord-256217-fnjer0e0 75 17 retinopathy retinopathy NN cord-256217-fnjer0e0 75 18 ( ( -LRB- cord-256217-fnjer0e0 75 19 ECOR ECOR NNP cord-256217-fnjer0e0 75 20 ) ) -RRB- cord-256217-fnjer0e0 75 21 is be VBZ cord-256217-fnjer0e0 75 22 associated associate VBN cord-256217-fnjer0e0 75 23 with with IN cord-256217-fnjer0e0 75 24 increased increase VBN cord-256217-fnjer0e0 75 25 TNF TNF NNP cord-256217-fnjer0e0 75 26 - - HYPH cord-256217-fnjer0e0 75 27 alpha alpha NN cord-256217-fnjer0e0 75 28 , , , cord-256217-fnjer0e0 75 29 soluble soluble JJ cord-256217-fnjer0e0 75 30 TNFR2 tnfr2 NN cord-256217-fnjer0e0 75 31 and and CC cord-256217-fnjer0e0 75 32 altered alter VBN cord-256217-fnjer0e0 75 33 TNF TNF NNP cord-256217-fnjer0e0 75 34 - - HYPH cord-256217-fnjer0e0 75 35 alpha alpha NN cord-256217-fnjer0e0 75 36 signaling signal VBG cord-256217-fnjer0e0 75 37 ERS/ ERS/ NNP cord-256217-fnjer0e0 75 38 ATS ATS NNP cord-256217-fnjer0e0 75 39 task task NN cord-256217-fnjer0e0 75 40 force force NN cord-256217-fnjer0e0 75 41 on on IN cord-256217-fnjer0e0 75 42 undifferentiated undifferentiated JJ cord-256217-fnjer0e0 75 43 forms form NNS cord-256217-fnjer0e0 75 44 of of IN cord-256217-fnjer0e0 75 45 CTD CTD NNP cord-256217-fnjer0e0 75 46 - - HYPH cord-256217-fnjer0e0 75 47 ILD ILD NNP cord-256217-fnjer0e0 75 48 ' ' '' cord-256217-fnjer0e0 75 49 ' ' '' cord-256217-fnjer0e0 75 50 . . . cord-256217-fnjer0e0 76 1 An an DT cord-256217-fnjer0e0 76 2 official official JJ cord-256217-fnjer0e0 76 3 European european JJ cord-256217-fnjer0e0 76 4 respiratory respiratory JJ cord-256217-fnjer0e0 76 5 society society NN cord-256217-fnjer0e0 76 6 / / SYM cord-256217-fnjer0e0 76 7 American american JJ cord-256217-fnjer0e0 76 8 thoracic thoracic JJ cord-256217-fnjer0e0 76 9 society society NN cord-256217-fnjer0e0 76 10 research research NN cord-256217-fnjer0e0 76 11 statement statement NN cord-256217-fnjer0e0 76 12 : : : cord-256217-fnjer0e0 76 13 interstitial interstitial JJ cord-256217-fnjer0e0 76 14 pneumonia pneumonia NN cord-256217-fnjer0e0 76 15 with with IN cord-256217-fnjer0e0 76 16 autoimmune autoimmune JJ cord-256217-fnjer0e0 76 17 features feature NNS cord-256217-fnjer0e0 77 1 Do do VBP cord-256217-fnjer0e0 77 2 corticosteroids corticosteroid NNS cord-256217-fnjer0e0 77 3 have have VB cord-256217-fnjer0e0 77 4 a a DT cord-256217-fnjer0e0 77 5 role role NN cord-256217-fnjer0e0 77 6 in in IN cord-256217-fnjer0e0 77 7 treating treat VBG cord-256217-fnjer0e0 77 8 Ebola Ebola NNP cord-256217-fnjer0e0 77 9 virus virus NN cord-256217-fnjer0e0 77 10 disease disease NN cord-256217-fnjer0e0 77 11 ? ? . cord-256217-fnjer0e0 78 1 Sci Sci NNP cord-256217-fnjer0e0 78 2 China China NNP cord-256217-fnjer0e0 79 1 On on IN cord-256217-fnjer0e0 79 2 the the DT cord-256217-fnjer0e0 79 3 use use NN cord-256217-fnjer0e0 79 4 of of IN cord-256217-fnjer0e0 79 5 corticosteroids corticosteroid NNS cord-256217-fnjer0e0 79 6 for for IN cord-256217-fnjer0e0 79 7 2019-nCoV 2019-ncov CD cord-256217-fnjer0e0 79 8 pneumonia pneumonia NN cord-256217-fnjer0e0 79 9 Herpes Herpes NNP cord-256217-fnjer0e0 79 10 simplex simplex NN cord-256217-fnjer0e0 79 11 virus virus NN cord-256217-fnjer0e0 79 12 encephalitis encephalitis RB cord-256217-fnjer0e0 79 13 update update VBP cord-256217-fnjer0e0 79 14 Diagnosis diagnosis NN cord-256217-fnjer0e0 79 15 and and CC cord-256217-fnjer0e0 79 16 treatment treatment NN cord-256217-fnjer0e0 79 17 of of IN cord-256217-fnjer0e0 79 18 viral viral JJ cord-256217-fnjer0e0 79 19 encephalitis encephalitis RB cord-256217-fnjer0e0 80 1 Exacerbated exacerbate VBN cord-256217-fnjer0e0 80 2 innate innate JJ cord-256217-fnjer0e0 80 3 host host NN cord-256217-fnjer0e0 80 4 response response NN cord-256217-fnjer0e0 80 5 to to IN cord-256217-fnjer0e0 80 6 SARS SARS NNP cord-256217-fnjer0e0 80 7 - - HYPH cord-256217-fnjer0e0 80 8 CoV CoV NNP cord-256217-fnjer0e0 80 9 in in IN cord-256217-fnjer0e0 80 10 aged aged JJ cord-256217-fnjer0e0 80 11 non non JJ cord-256217-fnjer0e0 80 12 - - JJ cord-256217-fnjer0e0 80 13 human human JJ cord-256217-fnjer0e0 80 14 primates primate NNS