id	sid	tid	token	lemma	pos
cord-029813-o2uzcuai	1	1	key	key	JJ
cord-029813-o2uzcuai	1	2	:	:	:
cord-029813-o2uzcuai	1	3	cord-029813-o2uzcuai	cord-029813-o2uzcuai	NN
cord-029813-o2uzcuai	1	4	authors	author	NNS
cord-029813-o2uzcuai	1	5	:	:	:
cord-029813-o2uzcuai	1	6	Rusconi	Rusconi	NNP
cord-029813-o2uzcuai	1	7	,	,	,
cord-029813-o2uzcuai	1	8	Stefano	Stefano	NNP
cord-029813-o2uzcuai	1	9	;	;	:
cord-029813-o2uzcuai	1	10	Hayden	Hayden	NNP
cord-029813-o2uzcuai	1	11	,	,	,
cord-029813-o2uzcuai	1	12	Frederick	Frederick	NNP
cord-029813-o2uzcuai	1	13	G	G	NNP
cord-029813-o2uzcuai	1	14	title	title	NN
cord-029813-o2uzcuai	1	15	:	:	:
cord-029813-o2uzcuai	1	16	COVID-19	covid-19	VB
cord-029813-o2uzcuai	1	17	:	:	:
cord-029813-o2uzcuai	1	18	studying	study	VBG
cord-029813-o2uzcuai	1	19	the	the	DT
cord-029813-o2uzcuai	1	20	global	global	JJ
cord-029813-o2uzcuai	1	21	pandemic	pandemic	NN
cord-029813-o2uzcuai	1	22	–	–	:
cord-029813-o2uzcuai	1	23	foreword	foreword	NN
cord-029813-o2uzcuai	1	24	date	date	NN
cord-029813-o2uzcuai	1	25	:	:	:
cord-029813-o2uzcuai	1	26	2020	2020	CD
cord-029813-o2uzcuai	1	27	-	-	HYPH
cord-029813-o2uzcuai	1	28	07	07	CD
cord-029813-o2uzcuai	1	29	-	-	HYPH
cord-029813-o2uzcuai	1	30	27	27	CD
cord-029813-o2uzcuai	1	31	journal	journal	NN
cord-029813-o2uzcuai	1	32	:	:	:
cord-029813-o2uzcuai	1	33	nan	nan	NNP
cord-029813-o2uzcuai	1	34	DOI	DOI	NNP
cord-029813-o2uzcuai	1	35	:	:	:
cord-029813-o2uzcuai	2	1	10.2217	10.2217	LS
cord-029813-o2uzcuai	2	2	/	/	SYM
cord-029813-o2uzcuai	2	3	fvl-2020	fvl-2020	NN
cord-029813-o2uzcuai	2	4	-	-	HYPH
cord-029813-o2uzcuai	2	5	0211	0211	CD
cord-029813-o2uzcuai	3	1	sha	sha	NNP
cord-029813-o2uzcuai	3	2	:	:	:
cord-029813-o2uzcuai	4	1	2650e12095dc06facf7de27cf00bc09e50404faa	2650e12095dc06facf7de27cf00bc09e50404faa	CD
cord-029813-o2uzcuai	4	2	doc_id	doc_id	CD
cord-029813-o2uzcuai	4	3	:	:	:
cord-029813-o2uzcuai	4	4	29813	29813	CD
cord-029813-o2uzcuai	4	5	cord_uid	cord_uid	FW
cord-029813-o2uzcuai	4	6	:	:	:
cord-029813-o2uzcuai	5	1	o2uzcuai	o2uzcuai	NNP
cord-029813-o2uzcuai	5	2	nan	nan	NNP
cord-029813-o2uzcuai	6	1	This	this	DT
cord-029813-o2uzcuai	6	2	special	special	JJ
cord-029813-o2uzcuai	6	3	issue	issue	NN
cord-029813-o2uzcuai	6	4	of	of	IN
cord-029813-o2uzcuai	6	5	Future	Future	NNP
cord-029813-o2uzcuai	6	6	Virology	Virology	NNP
cord-029813-o2uzcuai	6	7	contains	contain	VBZ
cord-029813-o2uzcuai	6	8	nine	nine	CD
cord-029813-o2uzcuai	6	9	articles	article	NNS
cord-029813-o2uzcuai	6	10	on	on	IN
cord-029813-o2uzcuai	6	11	diverse	diverse	JJ
cord-029813-o2uzcuai	6	12	aspects	aspect	NNS
cord-029813-o2uzcuai	6	13	of	of	IN
cord-029813-o2uzcuai	6	14	the	the	DT
cord-029813-o2uzcuai	6	15	COVID-19	covid-19	JJ
cord-029813-o2uzcuai	6	16	pandemic	pandemic	NN
cord-029813-o2uzcuai	6	17	and	and	CC
cord-029813-o2uzcuai	6	18	its	-PRON-	PRP$
cord-029813-o2uzcuai	6	19	causative	causative	JJ
cord-029813-o2uzcuai	6	20	agent	agent	NN
cord-029813-o2uzcuai	6	21	,	,	,
cord-029813-o2uzcuai	6	22	SARS	SARS	NNP
cord-029813-o2uzcuai	6	23	-	-	HYPH
cord-029813-o2uzcuai	6	24	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	6	25	.	.	.
cord-029813-o2uzcuai	7	1	The	the	DT
cord-029813-o2uzcuai	7	2	topics	topic	NNS
cord-029813-o2uzcuai	7	3	range	range	VBP
cord-029813-o2uzcuai	7	4	from	from	IN
cord-029813-o2uzcuai	7	5	basic	basic	JJ
cord-029813-o2uzcuai	7	6	virology	virology	NN
cord-029813-o2uzcuai	7	7	on	on	IN
cord-029813-o2uzcuai	7	8	coronavirus	coronavirus	NN
cord-029813-o2uzcuai	7	9	evolution	evolution	NN
cord-029813-o2uzcuai	7	10	and	and	CC
cord-029813-o2uzcuai	7	11	replication	replication	NN
cord-029813-o2uzcuai	7	12	to	to	IN
cord-029813-o2uzcuai	7	13	identification	identification	NN
cord-029813-o2uzcuai	7	14	of	of	IN
cord-029813-o2uzcuai	7	15	repurposed	repurpose	VBN
cord-029813-o2uzcuai	7	16	therapeutics	therapeutic	NNS
cord-029813-o2uzcuai	7	17	for	for	IN
cord-029813-o2uzcuai	7	18	clinical	clinical	JJ
cord-029813-o2uzcuai	7	19	testing	testing	NN
cord-029813-o2uzcuai	7	20	to	to	IN
cord-029813-o2uzcuai	7	21	public	public	JJ
cord-029813-o2uzcuai	7	22	health	health	NN
cord-029813-o2uzcuai	7	23	issues	issue	NNS
cord-029813-o2uzcuai	7	24	including	include	VBG
cord-029813-o2uzcuai	7	25	the	the	DT
cord-029813-o2uzcuai	7	26	conundrums	conundrum	NNS
cord-029813-o2uzcuai	7	27	of	of	IN
cord-029813-o2uzcuai	7	28	asymptomatic	asymptomatic	JJ
cord-029813-o2uzcuai	7	29	viral	viral	JJ
cord-029813-o2uzcuai	7	30	transmission	transmission	NN
cord-029813-o2uzcuai	7	31	and	and	CC
cord-029813-o2uzcuai	7	32	risks	risk	NNS
cord-029813-o2uzcuai	7	33	to	to	IN
cord-029813-o2uzcuai	7	34	homeless	homeless	JJ
cord-029813-o2uzcuai	7	35	populations	population	NNS
cord-029813-o2uzcuai	7	36	.	.	.
cord-029813-o2uzcuai	8	1	While	while	IN
cord-029813-o2uzcuai	8	2	several	several	JJ
cord-029813-o2uzcuai	8	3	of	of	IN
cord-029813-o2uzcuai	8	4	the	the	DT
cord-029813-o2uzcuai	8	5	reports	report	NNS
cord-029813-o2uzcuai	8	6	contain	contain	VBP
cord-029813-o2uzcuai	8	7	original	original	JJ
cord-029813-o2uzcuai	8	8	data	datum	NNS
cord-029813-o2uzcuai	8	9	,	,	,
cord-029813-o2uzcuai	8	10	others	other	NNS
cord-029813-o2uzcuai	8	11	are	be	VBP
cord-029813-o2uzcuai	8	12	Reviews	review	NNS
cord-029813-o2uzcuai	8	13	,	,	,
cord-029813-o2uzcuai	8	14	Special	Special	NNP
cord-029813-o2uzcuai	8	15	Reports	Reports	NNPS
cord-029813-o2uzcuai	8	16	or	or	CC
cord-029813-o2uzcuai	8	17	Commentaries	commentary	NNS
cord-029813-o2uzcuai	8	18	.	.	.
cord-029813-o2uzcuai	9	1	Given	give	VBN
cord-029813-o2uzcuai	9	2	the	the	DT
cord-029813-o2uzcuai	9	3	response	response	NN
cord-029813-o2uzcuai	9	4	of	of	IN
cord-029813-o2uzcuai	9	5	the	the	DT
cord-029813-o2uzcuai	9	6	global	global	JJ
cord-029813-o2uzcuai	9	7	research	research	NN
cord-029813-o2uzcuai	9	8	community	community	NN
cord-029813-o2uzcuai	9	9	to	to	IN
cord-029813-o2uzcuai	9	10	the	the	DT
cord-029813-o2uzcuai	9	11	pandemic	pandemic	NN
cord-029813-o2uzcuai	9	12	,	,	,
cord-029813-o2uzcuai	9	13	we	-PRON-	PRP
cord-029813-o2uzcuai	9	14	have	have	VBP
cord-029813-o2uzcuai	9	15	received	receive	VBN
cord-029813-o2uzcuai	9	16	unprecedented	unprecedented	JJ
cord-029813-o2uzcuai	9	17	submissions	submission	NNS
cord-029813-o2uzcuai	9	18	in	in	IN
cord-029813-o2uzcuai	9	19	this	this	DT
cord-029813-o2uzcuai	9	20	area	area	NN
cord-029813-o2uzcuai	9	21	and	and	CC
cord-029813-o2uzcuai	9	22	have	have	VBP
cord-029813-o2uzcuai	9	23	therefore	therefore	RB
cord-029813-o2uzcuai	9	24	compiled	compile	VBN
cord-029813-o2uzcuai	9	25	these	these	DT
cord-029813-o2uzcuai	9	26	into	into	IN
cord-029813-o2uzcuai	9	27	one	one	CD
cord-029813-o2uzcuai	9	28	issue	issue	NN
cord-029813-o2uzcuai	9	29	to	to	TO
cord-029813-o2uzcuai	9	30	provide	provide	VB
cord-029813-o2uzcuai	9	31	a	a	DT
cord-029813-o2uzcuai	9	32	useful	useful	JJ
cord-029813-o2uzcuai	9	33	resource	resource	NN
cord-029813-o2uzcuai	9	34	to	to	IN
cord-029813-o2uzcuai	9	35	those	those	DT
cord-029813-o2uzcuai	9	36	working	work	VBG
cord-029813-o2uzcuai	9	37	in	in	IN
cord-029813-o2uzcuai	9	38	the	the	DT
cord-029813-o2uzcuai	9	39	field	field	NN
cord-029813-o2uzcuai	9	40	.	.	.
cord-029813-o2uzcuai	10	1	While	while	IN
cord-029813-o2uzcuai	10	2	readers	reader	NNS
cord-029813-o2uzcuai	10	3	should	should	MD
cord-029813-o2uzcuai	10	4	be	be	VB
cord-029813-o2uzcuai	10	5	aware	aware	JJ
cord-029813-o2uzcuai	10	6	that	that	IN
cord-029813-o2uzcuai	10	7	all	all	DT
cord-029813-o2uzcuai	10	8	but	but	IN
cord-029813-o2uzcuai	10	9	one	one	CD
cord-029813-o2uzcuai	10	10	of	of	IN
cord-029813-o2uzcuai	10	11	the	the	DT
cord-029813-o2uzcuai	10	12	articles	article	NNS
cord-029813-o2uzcuai	10	13	have	have	VBP
cord-029813-o2uzcuai	10	14	undergone	undergo	VBN
cord-029813-o2uzcuai	10	15	external	external	JJ
cord-029813-o2uzcuai	10	16	peer	peer	NN
cord-029813-o2uzcuai	10	17	review	review	NN
cord-029813-o2uzcuai	10	18	,	,	,
cord-029813-o2uzcuai	10	19	as	as	IN
cord-029813-o2uzcuai	10	20	per	per	IN
cord-029813-o2uzcuai	10	21	the	the	DT
cord-029813-o2uzcuai	10	22	journal	journal	NN
cord-029813-o2uzcuai	10	23	's	's	POS
cord-029813-o2uzcuai	10	24	usual	usual	JJ
cord-029813-o2uzcuai	10	25	policies	policy	NNS
cord-029813-o2uzcuai	10	26	,	,	,
cord-029813-o2uzcuai	10	27	we	-PRON-	PRP
cord-029813-o2uzcuai	10	28	should	should	MD
cord-029813-o2uzcuai	10	29	point	point	VB
cord-029813-o2uzcuai	10	30	out	out	RP
cord-029813-o2uzcuai	10	31	that	that	IN
cord-029813-o2uzcuai	10	32	the	the	DT
cord-029813-o2uzcuai	10	33	conclusions	conclusion	NNS
cord-029813-o2uzcuai	10	34	and	and	CC
cord-029813-o2uzcuai	10	35	opinions	opinion	NNS
cord-029813-o2uzcuai	10	36	of	of	IN
cord-029813-o2uzcuai	10	37	some	some	DT
cord-029813-o2uzcuai	10	38	of	of	IN
cord-029813-o2uzcuai	10	39	the	the	DT
cord-029813-o2uzcuai	10	40	authors	author	NNS
cord-029813-o2uzcuai	10	41	are	be	VBP
cord-029813-o2uzcuai	10	42	speculative	speculative	JJ
cord-029813-o2uzcuai	10	43	.	.	.
cord-029813-o2uzcuai	11	1	The	the	DT
cord-029813-o2uzcuai	11	2	Commentary	commentary	NN
cord-029813-o2uzcuai	11	3	by	by	IN
cord-029813-o2uzcuai	11	4	Parvez	Parvez	NNP
cord-029813-o2uzcuai	11	5	[	[	-LRB-
cord-029813-o2uzcuai	11	6	1	1	CD
cord-029813-o2uzcuai	11	7	]	]	-RRB-
cord-029813-o2uzcuai	11	8	briefly	briefly	RB
cord-029813-o2uzcuai	11	9	reviews	review	VBZ
cord-029813-o2uzcuai	11	10	the	the	DT
cord-029813-o2uzcuai	11	11	detection	detection	NN
cord-029813-o2uzcuai	11	12	of	of	IN
cord-029813-o2uzcuai	11	13	SARS	SARS	NNP
cord-029813-o2uzcuai	11	14	-	-	HYPH
cord-029813-o2uzcuai	11	15	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	11	16	RNA	RNA	NNP
cord-029813-o2uzcuai	11	17	in	in	IN
cord-029813-o2uzcuai	11	18	fecal	fecal	JJ
cord-029813-o2uzcuai	11	19	samples	sample	NNS
cord-029813-o2uzcuai	11	20	,	,	,
cord-029813-o2uzcuai	11	21	including	include	VBG
cord-029813-o2uzcuai	11	22	its	-PRON-	PRP$
cord-029813-o2uzcuai	11	23	persistence	persistence	NN
cord-029813-o2uzcuai	11	24	,	,	,
cord-029813-o2uzcuai	11	25	and	and	CC
cord-029813-o2uzcuai	11	26	the	the	DT
cord-029813-o2uzcuai	11	27	finding	finding	NN
cord-029813-o2uzcuai	11	28	of	of	IN
cord-029813-o2uzcuai	11	29	gastrointestinal	gastrointestinal	JJ
cord-029813-o2uzcuai	11	30	complaints	complaint	NNS
cord-029813-o2uzcuai	11	31	in	in	IN
cord-029813-o2uzcuai	11	32	a	a	DT
cord-029813-o2uzcuai	11	33	minority	minority	NN
cord-029813-o2uzcuai	11	34	of	of	IN
cord-029813-o2uzcuai	11	35	hospitalized	hospitalize	VBN
cord-029813-o2uzcuai	11	36	patients	patient	NNS
cord-029813-o2uzcuai	11	37	.	.	.
cord-029813-o2uzcuai	12	1	Others	other	NNS
cord-029813-o2uzcuai	12	2	have	have	VBP
cord-029813-o2uzcuai	12	3	also	also	RB
cord-029813-o2uzcuai	12	4	highlighted	highlight	VBN
cord-029813-o2uzcuai	12	5	that	that	IN
cord-029813-o2uzcuai	12	6	some	some	DT
cord-029813-o2uzcuai	12	7	COVID-19	covid-19	CD
cord-029813-o2uzcuai	12	8	patients	patient	NNS
cord-029813-o2uzcuai	12	9	present	present	VBP
cord-029813-o2uzcuai	12	10	primarily	primarily	RB
cord-029813-o2uzcuai	12	11	or	or	CC
cord-029813-o2uzcuai	12	12	exclusively	exclusively	RB
cord-029813-o2uzcuai	12	13	with	with	IN
cord-029813-o2uzcuai	12	14	gastrointestinal	gastrointestinal	JJ
cord-029813-o2uzcuai	12	15	manifestations	manifestation	NNS
cord-029813-o2uzcuai	12	16	.	.	.
cord-029813-o2uzcuai	13	1	Given	give	VBN
cord-029813-o2uzcuai	13	2	the	the	DT
cord-029813-o2uzcuai	13	3	presence	presence	NN
cord-029813-o2uzcuai	13	4	of	of	IN
cord-029813-o2uzcuai	13	5	ACE-2	ACE-2	NNP
cord-029813-o2uzcuai	13	6	receptors	receptor	NNS
cord-029813-o2uzcuai	13	7	in	in	IN
cord-029813-o2uzcuai	13	8	intestinal	intestinal	JJ
cord-029813-o2uzcuai	13	9	epithelial	epithelial	JJ
cord-029813-o2uzcuai	13	10	cells	cell	NNS
cord-029813-o2uzcuai	13	11	and	and	CC
cord-029813-o2uzcuai	13	12	the	the	DT
cord-029813-o2uzcuai	13	13	documentation	documentation	NN
cord-029813-o2uzcuai	13	14	of	of	IN
cord-029813-o2uzcuai	13	15	SARS	SARS	NNP
cord-029813-o2uzcuai	13	16	-	-	HYPH
cord-029813-o2uzcuai	13	17	CoV-1	CoV-1	NNP
cord-029813-o2uzcuai	13	18	infection	infection	NN
cord-029813-o2uzcuai	13	19	involving	involve	VBG
cord-029813-o2uzcuai	13	20	the	the	DT
cord-029813-o2uzcuai	13	21	gastrointestinal	gastrointestinal	JJ
cord-029813-o2uzcuai	13	22	tract	tract	NN
cord-029813-o2uzcuai	13	23	,	,	,
cord-029813-o2uzcuai	13	24	it	-PRON-	PRP
cord-029813-o2uzcuai	13	25	is	be	VBZ
cord-029813-o2uzcuai	13	26	not	not	RB
cord-029813-o2uzcuai	13	27	surprising	surprising	JJ
cord-029813-o2uzcuai	13	28	that	that	IN
cord-029813-o2uzcuai	13	29	the	the	DT
cord-029813-o2uzcuai	13	30	SARS	SARS	NNP
cord-029813-o2uzcuai	13	31	-	-	HYPH
cord-029813-o2uzcuai	13	32	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	13	33	might	may	MD
cord-029813-o2uzcuai	13	34	also	also	RB
cord-029813-o2uzcuai	13	35	cause	cause	VB
cord-029813-o2uzcuai	13	36	such	such	JJ
cord-029813-o2uzcuai	13	37	infections	infection	NNS
cord-029813-o2uzcuai	13	38	and	and	CC
cord-029813-o2uzcuai	13	39	associated	associate	VBN
cord-029813-o2uzcuai	13	40	illness	illness	NN
cord-029813-o2uzcuai	13	41	.	.	.
cord-029813-o2uzcuai	14	1	Of	of	RB
cord-029813-o2uzcuai	14	2	course	course	RB
cord-029813-o2uzcuai	14	3	,	,	,
cord-029813-o2uzcuai	14	4	fecal	fecal	JJ
cord-029813-o2uzcuai	14	5	aerosols	aerosol	NNS
cord-029813-o2uzcuai	14	6	were	be	VBD
cord-029813-o2uzcuai	14	7	implicated	implicate	VBN
cord-029813-o2uzcuai	14	8	in	in	IN
cord-029813-o2uzcuai	14	9	a	a	DT
cord-029813-o2uzcuai	14	10	very	very	RB
cord-029813-o2uzcuai	14	11	large	large	JJ
cord-029813-o2uzcuai	14	12	SARS	SARS	NNP
cord-029813-o2uzcuai	14	13	outbreaks	outbreak	NNS
cord-029813-o2uzcuai	14	14	in	in	IN
cord-029813-o2uzcuai	14	15	Hong	Hong	NNP
cord-029813-o2uzcuai	14	16	Kong	Kong	NNP
cord-029813-o2uzcuai	14	17	in	in	IN
cord-029813-o2uzcuai	14	18	2003	2003	CD
cord-029813-o2uzcuai	14	19	.	.	.
cord-029813-o2uzcuai	15	1	However	however	RB
cord-029813-o2uzcuai	15	2	,	,	,
cord-029813-o2uzcuai	15	3	infectious	infectious	JJ
cord-029813-o2uzcuai	15	4	SARS	SARS	NNP
cord-029813-o2uzcuai	15	5	-	-	HYPH
cord-029813-o2uzcuai	15	6	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	15	7	has	have	VBZ
cord-029813-o2uzcuai	15	8	been	be	VBN
cord-029813-o2uzcuai	15	9	only	only	RB
cord-029813-o2uzcuai	15	10	rarely	rarely	RB
cord-029813-o2uzcuai	15	11	isolated	isolate	VBN
cord-029813-o2uzcuai	15	12	from	from	IN
cord-029813-o2uzcuai	15	13	fecal	fecal	JJ
cord-029813-o2uzcuai	15	14	samples	sample	NNS
cord-029813-o2uzcuai	15	15	to	to	IN
cord-029813-o2uzcuai	15	16	date	date	NN
cord-029813-o2uzcuai	15	17	,	,	,
cord-029813-o2uzcuai	15	18	and	and	CC
cord-029813-o2uzcuai	15	19	the	the	DT
cord-029813-o2uzcuai	15	20	possible	possible	JJ
cord-029813-o2uzcuai	15	21	risks	risk	NNS
cord-029813-o2uzcuai	15	22	of	of	IN
cord-029813-o2uzcuai	15	23	fecal	fecal	JJ
cord-029813-o2uzcuai	15	24	-	-	HYPH
cord-029813-o2uzcuai	15	25	oral	oral	JJ
cord-029813-o2uzcuai	15	26	or	or	CC
cord-029813-o2uzcuai	15	27	fecal	fecal	JJ
cord-029813-o2uzcuai	15	28	-	-	HYPH
cord-029813-o2uzcuai	15	29	aerosol	aerosol	NN
cord-029813-o2uzcuai	15	30	transmission	transmission	NN
cord-029813-o2uzcuai	15	31	remain	remain	VBP
cord-029813-o2uzcuai	15	32	to	to	TO
cord-029813-o2uzcuai	15	33	be	be	VB
cord-029813-o2uzcuai	15	34	clarified	clarify	VBN
cord-029813-o2uzcuai	15	35	.	.	.
cord-029813-o2uzcuai	16	1	Interestingly	interestingly	RB
cord-029813-o2uzcuai	16	2	,	,	,
cord-029813-o2uzcuai	16	3	Parvez	Parvez	NNP
cord-029813-o2uzcuai	16	4	points	point	VBZ
cord-029813-o2uzcuai	16	5	out	out	RP
cord-029813-o2uzcuai	16	6	the	the	DT
cord-029813-o2uzcuai	16	7	greater	great	JJR
cord-029813-o2uzcuai	16	8	expression	expression	NN
cord-029813-o2uzcuai	16	9	of	of	IN
cord-029813-o2uzcuai	16	10	ACE-2	ACE-2	NNP
cord-029813-o2uzcuai	16	11	receptor	receptor	NN
cord-029813-o2uzcuai	16	12	in	in	IN
cord-029813-o2uzcuai	16	13	cholangiocytes	cholangiocyte	NNS
cord-029813-o2uzcuai	16	14	than	than	IN
cord-029813-o2uzcuai	16	15	hepatocytes	hepatocyte	NNS
cord-029813-o2uzcuai	16	16	in	in	IN
cord-029813-o2uzcuai	16	17	COVID-19	covid-19	JJ
cord-029813-o2uzcuai	16	18	patients	patient	NNS
cord-029813-o2uzcuai	16	19	and	and	CC
cord-029813-o2uzcuai	16	20	speculates	speculate	VBZ
cord-029813-o2uzcuai	16	21	about	about	IN
cord-029813-o2uzcuai	16	22	how	how	WRB
cord-029813-o2uzcuai	16	23	this	this	DT
cord-029813-o2uzcuai	16	24	and	and	CC
cord-029813-o2uzcuai	16	25	other	other	JJ
cord-029813-o2uzcuai	16	26	mechanisms	mechanism	NNS
cord-029813-o2uzcuai	16	27	,	,	,
cord-029813-o2uzcuai	16	28	particularly	particularly	RB
cord-029813-o2uzcuai	16	29	immune	immune	JJ
cord-029813-o2uzcuai	16	30	-	-	HYPH
cord-029813-o2uzcuai	16	31	mediated	mediate	VBN
cord-029813-o2uzcuai	16	32	ones	one	NNS
cord-029813-o2uzcuai	16	33	,	,	,
cord-029813-o2uzcuai	16	34	might	may	MD
cord-029813-o2uzcuai	16	35	be	be	VB
cord-029813-o2uzcuai	16	36	contributing	contribute	VBG
cord-029813-o2uzcuai	16	37	to	to	IN
cord-029813-o2uzcuai	16	38	the	the	DT
cord-029813-o2uzcuai	16	39	substantial	substantial	JJ
cord-029813-o2uzcuai	16	40	frequency	frequency	NN
cord-029813-o2uzcuai	16	41	of	of	IN
cord-029813-o2uzcuai	16	42	hepatic	hepatic	JJ
cord-029813-o2uzcuai	16	43	abnormalities	abnormality	NNS
cord-029813-o2uzcuai	16	44	seen	see	VBN
cord-029813-o2uzcuai	16	45	in	in	IN
cord-029813-o2uzcuai	16	46	hospitalized	hospitalize	VBN
cord-029813-o2uzcuai	16	47	patients	patient	NNS
cord-029813-o2uzcuai	16	48	.	.	.
cord-029813-o2uzcuai	17	1	Of	of	RB
cord-029813-o2uzcuai	17	2	course	course	RB
cord-029813-o2uzcuai	17	3	,	,	,
cord-029813-o2uzcuai	17	4	other	other	JJ
cord-029813-o2uzcuai	17	5	factors	factor	NNS
cord-029813-o2uzcuai	17	6	including	include	VBG
cord-029813-o2uzcuai	17	7	hypoxemia	hypoxemia	NN
cord-029813-o2uzcuai	17	8	,	,	,
cord-029813-o2uzcuai	17	9	ischemia	ischemia	NN
cord-029813-o2uzcuai	17	10	and	and	CC
cord-029813-o2uzcuai	17	11	medication	medication	NN
cord-029813-o2uzcuai	17	12	side	side	NN
cord-029813-o2uzcuai	17	13	effects	effect	NNS
cord-029813-o2uzcuai	17	14	are	be	VBP
cord-029813-o2uzcuai	17	15	also	also	RB
cord-029813-o2uzcuai	17	16	likely	likely	JJ
cord-029813-o2uzcuai	17	17	to	to	TO
cord-029813-o2uzcuai	17	18	be	be	VB
cord-029813-o2uzcuai	17	19	contributory	contributory	JJ
cord-029813-o2uzcuai	17	20	.	.	.
cord-029813-o2uzcuai	18	1	The	the	DT
cord-029813-o2uzcuai	18	2	latter	latter	JJ
cord-029813-o2uzcuai	18	3	concern	concern	NN
cord-029813-o2uzcuai	18	4	has	have	VBZ
cord-029813-o2uzcuai	18	5	led	lead	VBN
cord-029813-o2uzcuai	18	6	to	to	IN
cord-029813-o2uzcuai	18	7	premature	premature	JJ
cord-029813-o2uzcuai	18	8	discontinuation	discontinuation	NN
cord-029813-o2uzcuai	18	9	of	of	IN
cord-029813-o2uzcuai	18	10	intravenous	intravenous	JJ
cord-029813-o2uzcuai	18	11	remdesivir	remdesivir	NN
cord-029813-o2uzcuai	18	12	therapy	therapy	NN
cord-029813-o2uzcuai	18	13	in	in	IN
cord-029813-o2uzcuai	18	14	hospitalized	hospitalize	VBN
cord-029813-o2uzcuai	18	15	COVID-19	COVID-19	NNP
cord-029813-o2uzcuai	18	16	patients	patient	NNS
cord-029813-o2uzcuai	18	17	.	.	.
cord-029813-o2uzcuai	19	1	The	the	DT
cord-029813-o2uzcuai	19	2	immunopathologic	immunopathologic	JJ
cord-029813-o2uzcuai	19	3	effects	effect	NNS
cord-029813-o2uzcuai	19	4	of	of	IN
cord-029813-o2uzcuai	19	5	pro	pro	JJ
cord-029813-o2uzcuai	19	6	-	-	JJ
cord-029813-o2uzcuai	19	7	inflammatory	inflammatory	JJ
cord-029813-o2uzcuai	19	8	cytokines	cytokine	NNS
cord-029813-o2uzcuai	19	9	like	like	IN
cord-029813-o2uzcuai	19	10	IL-6	IL-6	NNP
cord-029813-o2uzcuai	19	11	are	be	VBP
cord-029813-o2uzcuai	19	12	the	the	DT
cord-029813-o2uzcuai	19	13	subject	subject	NN
cord-029813-o2uzcuai	19	14	of	of	IN
cord-029813-o2uzcuai	19	15	ongoing	ongoing	JJ
cord-029813-o2uzcuai	19	16	randomized	randomized	JJ
cord-029813-o2uzcuai	19	17	,	,	,
cord-029813-o2uzcuai	19	18	controlled	control	VBN
cord-029813-o2uzcuai	19	19	trials	trial	NNS
cord-029813-o2uzcuai	19	20	in	in	IN
cord-029813-o2uzcuai	19	21	severe	severe	JJ
cord-029813-o2uzcuai	19	22	COVID-19	covid-19	NN
cord-029813-o2uzcuai	19	23	.	.	.
cord-029813-o2uzcuai	20	1	The	the	DT
cord-029813-o2uzcuai	20	2	thoughtful	thoughtful	JJ
cord-029813-o2uzcuai	20	3	Commentary	commentary	NN
cord-029813-o2uzcuai	20	4	article	article	NN
cord-029813-o2uzcuai	20	5	by	by	IN
cord-029813-o2uzcuai	20	6	Conway	Conway	NNP
cord-029813-o2uzcuai	20	7	et	et	NNP
cord-029813-o2uzcuai	20	8	al	al	NNP
cord-029813-o2uzcuai	20	9	.	.	.
cord-029813-o2uzcuai	21	1	[	[	-LRB-
cord-029813-o2uzcuai	21	2	2	2	CD
cord-029813-o2uzcuai	21	3	]	]	-RRB-
cord-029813-o2uzcuai	21	4	addresses	address	VBZ
cord-029813-o2uzcuai	21	5	the	the	DT
cord-029813-o2uzcuai	21	6	extraordinary	extraordinary	JJ
cord-029813-o2uzcuai	21	7	challenges	challenge	NNS
cord-029813-o2uzcuai	21	8	of	of	IN
cord-029813-o2uzcuai	21	9	mitigating	mitigate	VBG
cord-029813-o2uzcuai	21	10	COVID-19	covid-19	JJ
cord-029813-o2uzcuai	21	11	risks	risk	NNS
cord-029813-o2uzcuai	21	12	in	in	IN
cord-029813-o2uzcuai	21	13	homeless	homeless	JJ
cord-029813-o2uzcuai	21	14	persons	person	NNS
cord-029813-o2uzcuai	21	15	in	in	IN
cord-029813-o2uzcuai	21	16	central	central	JJ
cord-029813-o2uzcuai	21	17	Vancouver	Vancouver	NNP
cord-029813-o2uzcuai	21	18	(	(	-LRB-
cord-029813-o2uzcuai	21	19	BC	BC	NNP
cord-029813-o2uzcuai	21	20	,	,	,
cord-029813-o2uzcuai	21	21	CA	CA	NNP
cord-029813-o2uzcuai	21	22	,	,	,
cord-029813-o2uzcuai	21	23	USA	USA	NNP
cord-029813-o2uzcuai	21	24	)	)	-RRB-
cord-029813-o2uzcuai	21	25	.	.	.
cord-029813-o2uzcuai	22	1	Like	like	IN
cord-029813-o2uzcuai	22	2	many	many	JJ
cord-029813-o2uzcuai	22	3	other	other	JJ
cord-029813-o2uzcuai	22	4	inner	inner	JJ
cord-029813-o2uzcuai	22	5	city	city	NN
cord-029813-o2uzcuai	22	6	populations	population	NNS
cord-029813-o2uzcuai	22	7	,	,	,
cord-029813-o2uzcuai	22	8	the	the	DT
cord-029813-o2uzcuai	22	9	one	one	CD
cord-029813-o2uzcuai	22	10	in	in	IN
cord-029813-o2uzcuai	22	11	Vancouver	Vancouver	NNP
cord-029813-o2uzcuai	22	12	has	have	VBZ
cord-029813-o2uzcuai	22	13	high	high	JJ
cord-029813-o2uzcuai	22	14	frequencies	frequency	NNS
cord-029813-o2uzcuai	22	15	of	of	IN
cord-029813-o2uzcuai	22	16	psychiatric	psychiatric	JJ
cord-029813-o2uzcuai	22	17	disorders	disorder	NNS
cord-029813-o2uzcuai	22	18	,	,	,
cord-029813-o2uzcuai	22	19	opiate	opiate	JJ
cord-029813-o2uzcuai	22	20	drug	drug	NN
cord-029813-o2uzcuai	22	21	dependence	dependence	NN
cord-029813-o2uzcuai	22	22	and	and	CC
cord-029813-o2uzcuai	22	23	overdose	overdose	NN
cord-029813-o2uzcuai	22	24	-	-	HYPH
cord-029813-o2uzcuai	22	25	related	relate	VBN
cord-029813-o2uzcuai	22	26	deaths	death	NNS
cord-029813-o2uzcuai	22	27	.	.	.
cord-029813-o2uzcuai	23	1	Sadly	sadly	RB
cord-029813-o2uzcuai	23	2	,	,	,
cord-029813-o2uzcuai	23	3	the	the	DT
cord-029813-o2uzcuai	23	4	latter	latter	JJ
cord-029813-o2uzcuai	23	5	increased	increase	VBD
cord-029813-o2uzcuai	23	6	temporally	temporally	RB
cord-029813-o2uzcuai	23	7	with	with	IN
cord-029813-o2uzcuai	23	8	loss	loss	NN
cord-029813-o2uzcuai	23	9	of	of	IN
cord-029813-o2uzcuai	23	10	many	many	JJ
cord-029813-o2uzcuai	23	11	supportive	supportive	JJ
cord-029813-o2uzcuai	23	12	services	service	NNS
cord-029813-o2uzcuai	23	13	in	in	IN
cord-029813-o2uzcuai	23	14	efforts	effort	NNS
cord-029813-o2uzcuai	23	15	at	at	IN
cord-029813-o2uzcuai	23	16	social	social	JJ
cord-029813-o2uzcuai	23	17	distancing	distancing	NN
cord-029813-o2uzcuai	23	18	,	,	,
cord-029813-o2uzcuai	23	19	including	include	VBG
cord-029813-o2uzcuai	23	20	loss	loss	NN
cord-029813-o2uzcuai	23	21	of	of	IN
cord-029813-o2uzcuai	23	22	daily	daily	JJ
cord-029813-o2uzcuai	23	23	directly	directly	RB
cord-029813-o2uzcuai	23	24	observed	observe	VBN
cord-029813-o2uzcuai	23	25	drug	drug	NN
cord-029813-o2uzcuai	23	26	administration	administration	NN
cord-029813-o2uzcuai	23	27	.	.	.
cord-029813-o2uzcuai	24	1	The	the	DT
cord-029813-o2uzcuai	24	2	authors	author	NNS
cord-029813-o2uzcuai	24	3	describe	describe	VBP
cord-029813-o2uzcuai	24	4	the	the	DT
cord-029813-o2uzcuai	24	5	difficult	difficult	JJ
cord-029813-o2uzcuai	24	6	choices	choice	NNS
cord-029813-o2uzcuai	24	7	faced	face	VBN
cord-029813-o2uzcuai	24	8	by	by	IN
cord-029813-o2uzcuai	24	9	city	city	NN
cord-029813-o2uzcuai	24	10	administrators	administrator	NNS
cord-029813-o2uzcuai	24	11	and	and	CC
cord-029813-o2uzcuai	24	12	private	private	JJ
cord-029813-o2uzcuai	24	13	entities	entity	NNS
cord-029813-o2uzcuai	24	14	in	in	IN
cord-029813-o2uzcuai	24	15	balancing	balance	VBG
cord-029813-o2uzcuai	24	16	infection	infection	NN
cord-029813-o2uzcuai	24	17	risks	risk	NNS
cord-029813-o2uzcuai	24	18	to	to	IN
cord-029813-o2uzcuai	24	19	staff	staff	NN
cord-029813-o2uzcuai	24	20	and	and	CC
cord-029813-o2uzcuai	24	21	maintenance	maintenance	NN
cord-029813-o2uzcuai	24	22	of	of	IN
cord-029813-o2uzcuai	24	23	essential	essential	JJ
cord-029813-o2uzcuai	24	24	services	service	NNS
cord-029813-o2uzcuai	24	25	.	.	.
cord-029813-o2uzcuai	25	1	They	-PRON-	PRP
cord-029813-o2uzcuai	25	2	then	then	RB
cord-029813-o2uzcuai	25	3	propose	propose	VBP
cord-029813-o2uzcuai	25	4	specific	specific	JJ
cord-029813-o2uzcuai	25	5	strategies	strategy	NNS
cord-029813-o2uzcuai	25	6	to	to	TO
cord-029813-o2uzcuai	25	7	improve	improve	VB
cord-029813-o2uzcuai	25	8	current	current	JJ
cord-029813-o2uzcuai	25	9	circumstances	circumstance	NNS
cord-029813-o2uzcuai	25	10	and	and	CC
cord-029813-o2uzcuai	25	11	also	also	RB
cord-029813-o2uzcuai	25	12	emphasize	emphasize	VB
cord-029813-o2uzcuai	25	13	the	the	DT
cord-029813-o2uzcuai	25	14	long	long	JJ
cord-029813-o2uzcuai	25	15	-	-	HYPH
cord-029813-o2uzcuai	25	16	term	term	NN
cord-029813-o2uzcuai	25	17	need	need	NN
cord-029813-o2uzcuai	25	18	for	for	IN
cord-029813-o2uzcuai	25	19	stable	stable	JJ
cord-029813-o2uzcuai	25	20	housing	housing	NN
cord-029813-o2uzcuai	25	21	.	.	.
cord-029813-o2uzcuai	26	1	These	these	DT
cord-029813-o2uzcuai	26	2	recommendations	recommendation	NNS
cord-029813-o2uzcuai	26	3	are	be	VBP
cord-029813-o2uzcuai	26	4	highly	highly	RB
cord-029813-o2uzcuai	26	5	relevant	relevant	JJ
cord-029813-o2uzcuai	26	6	for	for	IN
cord-029813-o2uzcuai	26	7	essentially	essentially	RB
cord-029813-o2uzcuai	26	8	all	all	DT
cord-029813-o2uzcuai	26	9	urban	urban	JJ
cord-029813-o2uzcuai	26	10	centers	center	NNS
cord-029813-o2uzcuai	26	11	that	that	WDT
cord-029813-o2uzcuai	26	12	harbor	harbor	VBP
cord-029813-o2uzcuai	26	13	such	such	JJ
cord-029813-o2uzcuai	26	14	populations	population	NNS
cord-029813-o2uzcuai	26	15	of	of	IN
cord-029813-o2uzcuai	26	16	high	high	JJ
cord-029813-o2uzcuai	26	17	-	-	HYPH
cord-029813-o2uzcuai	26	18	risk	risk	NN
cord-029813-o2uzcuai	26	19	persons	person	NNS
cord-029813-o2uzcuai	26	20	and	and	CC
cord-029813-o2uzcuai	26	21	reflect	reflect	VBP
cord-029813-o2uzcuai	26	22	more	more	RBR
cord-029813-o2uzcuai	26	23	broadly	broadly	RB
cord-029813-o2uzcuai	26	24	the	the	DT
cord-029813-o2uzcuai	26	25	challenges	challenge	NNS
cord-029813-o2uzcuai	26	26	in	in	IN
cord-029813-o2uzcuai	26	27	mitigating	mitigate	VBG
cord-029813-o2uzcuai	26	28	infection	infection	NN
cord-029813-o2uzcuai	26	29	risks	risk	NNS
cord-029813-o2uzcuai	26	30	in	in	IN
cord-029813-o2uzcuai	26	31	other	other	JJ
cord-029813-o2uzcuai	26	32	disenfranchised	disenfranchised	JJ
cord-029813-o2uzcuai	26	33	populations	population	NNS
cord-029813-o2uzcuai	26	34	,	,	,
cord-029813-o2uzcuai	26	35	like	like	IN
cord-029813-o2uzcuai	26	36	those	those	DT
cord-029813-o2uzcuai	26	37	in	in	IN
cord-029813-o2uzcuai	26	38	refugee	refugee	NN
cord-029813-o2uzcuai	26	39	camps	camp	NNS
cord-029813-o2uzcuai	26	40	.	.	.
cord-029813-o2uzcuai	27	1	Of	of	RB
cord-029813-o2uzcuai	27	2	course	course	RB
cord-029813-o2uzcuai	27	3	,	,	,
cord-029813-o2uzcuai	27	4	once	once	RB
cord-029813-o2uzcuai	27	5	a	a	DT
cord-029813-o2uzcuai	27	6	safe	safe	JJ
cord-029813-o2uzcuai	27	7	and	and	CC
cord-029813-o2uzcuai	27	8	effective	effective	JJ
cord-029813-o2uzcuai	27	9	SARS	SARS	NNP
cord-029813-o2uzcuai	27	10	-	-	HYPH
cord-029813-o2uzcuai	27	11	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	27	12	vaccine	vaccine	NN
cord-029813-o2uzcuai	27	13	becomes	become	VBZ
cord-029813-o2uzcuai	27	14	available	available	JJ
cord-029813-o2uzcuai	27	15	,	,	,
cord-029813-o2uzcuai	27	16	immunization	immunization	NN
cord-029813-o2uzcuai	27	17	of	of	IN
cord-029813-o2uzcuai	27	18	such	such	JJ
cord-029813-o2uzcuai	27	19	high	high	JJ
cord-029813-o2uzcuai	27	20	-	-	HYPH
cord-029813-o2uzcuai	27	21	risk	risk	NN
cord-029813-o2uzcuai	27	22	populations	population	NNS
cord-029813-o2uzcuai	27	23	will	will	MD
cord-029813-o2uzcuai	27	24	be	be	VB
cord-029813-o2uzcuai	27	25	a	a	DT
cord-029813-o2uzcuai	27	26	priority	priority	NN
cord-029813-o2uzcuai	27	27	,	,	,
cord-029813-o2uzcuai	27	28	as	as	IN
cord-029813-o2uzcuai	27	29	has	have	VBZ
cord-029813-o2uzcuai	27	30	been	be	VBN
cord-029813-o2uzcuai	27	31	shown	show	VBN
cord-029813-o2uzcuai	27	32	by	by	IN
cord-029813-o2uzcuai	27	33	the	the	DT
cord-029813-o2uzcuai	27	34	deployment	deployment	NN
cord-029813-o2uzcuai	27	35	of	of	IN
cord-029813-o2uzcuai	27	36	hepatitis	hepatitis	NNP
cord-029813-o2uzcuai	27	37	A	A	NNP
cord-029813-o2uzcuai	27	38	virus	virus	NN
cord-029813-o2uzcuai	27	39	vaccine	vaccine	NN
cord-029813-o2uzcuai	27	40	to	to	TO
cord-029813-o2uzcuai	27	41	mitigate	mitigate	VB
cord-029813-o2uzcuai	27	42	outbreaks	outbreak	NNS
cord-029813-o2uzcuai	27	43	in	in	IN
cord-029813-o2uzcuai	27	44	homeless	homeless	JJ
cord-029813-o2uzcuai	27	45	populations	population	NNS
cord-029813-o2uzcuai	27	46	in	in	IN
cord-029813-o2uzcuai	27	47	North	North	NNP
cord-029813-o2uzcuai	27	48	America	America	NNP
cord-029813-o2uzcuai	27	49	.	.	.
cord-029813-o2uzcuai	28	1	Yang	Yang	NNP
cord-029813-o2uzcuai	28	2	et	et	NNP
cord-029813-o2uzcuai	28	3	al	al	NNP
cord-029813-o2uzcuai	28	4	.	.	.
cord-029813-o2uzcuai	29	1	[	[	-LRB-
cord-029813-o2uzcuai	29	2	3	3	LS
cord-029813-o2uzcuai	29	3	]	]	-RRB-
cord-029813-o2uzcuai	29	4	report	report	VB
cord-029813-o2uzcuai	29	5	the	the	DT
cord-029813-o2uzcuai	29	6	case	case	NN
cord-029813-o2uzcuai	29	7	of	of	IN
cord-029813-o2uzcuai	29	8	a	a	DT
cord-029813-o2uzcuai	29	9	57-year	57-year	JJ
cord-029813-o2uzcuai	29	10	-	-	HYPH
cord-029813-o2uzcuai	29	11	old	old	JJ
cord-029813-o2uzcuai	29	12	patient	patient	NN
cord-029813-o2uzcuai	29	13	who	who	WP
cord-029813-o2uzcuai	29	14	had	have	VBD
cord-029813-o2uzcuai	29	15	a	a	DT
cord-029813-o2uzcuai	29	16	positive	positive	JJ
cord-029813-o2uzcuai	29	17	RT	rt	NN
cord-029813-o2uzcuai	29	18	-	-	HYPH
cord-029813-o2uzcuai	29	19	PCR	PCR	NNP
cord-029813-o2uzcuai	29	20	for	for	IN
cord-029813-o2uzcuai	29	21	SARS	SARS	NNP
cord-029813-o2uzcuai	29	22	-	-	HYPH
cord-029813-o2uzcuai	29	23	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	29	24	after	after	IN
cord-029813-o2uzcuai	29	25	three	three	CD
cord-029813-o2uzcuai	29	26	negative	negative	JJ
cord-029813-o2uzcuai	29	27	sputum	sputum	NN
cord-029813-o2uzcuai	29	28	tests	test	NNS
cord-029813-o2uzcuai	29	29	in	in	IN
cord-029813-o2uzcuai	29	30	the	the	DT
cord-029813-o2uzcuai	29	31	context	context	NN
cord-029813-o2uzcuai	29	32	of	of	IN
cord-029813-o2uzcuai	29	33	mild	mild	JJ
cord-029813-o2uzcuai	29	34	illness	illness	NN
cord-029813-o2uzcuai	29	35	.	.	.
cord-029813-o2uzcuai	30	1	The	the	DT
cord-029813-o2uzcuai	30	2	patient	patient	NN
cord-029813-o2uzcuai	30	3	was	be	VBD
cord-029813-o2uzcuai	30	4	caring	care	VBG
cord-029813-o2uzcuai	30	5	for	for	IN
cord-029813-o2uzcuai	30	6	her	-PRON-	PRP$
cord-029813-o2uzcuai	30	7	father	father	NN
cord-029813-o2uzcuai	30	8	from	from	IN
cord-029813-o2uzcuai	30	9	1	1	CD
cord-029813-o2uzcuai	30	10	to	to	IN
cord-029813-o2uzcuai	30	11	6	6	CD
cord-029813-o2uzcuai	30	12	February	February	NNP
cord-029813-o2uzcuai	30	13	2020	2020	CD
cord-029813-o2uzcuai	30	14	,	,	,
cord-029813-o2uzcuai	30	15	after	after	IN
cord-029813-o2uzcuai	30	16	her	-PRON-	PRP$
cord-029813-o2uzcuai	30	17	mother	mother	NN
cord-029813-o2uzcuai	30	18	died	die	VBD
cord-029813-o2uzcuai	30	19	from	from	IN
cord-029813-o2uzcuai	30	20	cardiac	cardiac	JJ
cord-029813-o2uzcuai	30	21	complications	complication	NNS
cord-029813-o2uzcuai	30	22	.	.	.
cord-029813-o2uzcuai	31	1	Her	-PRON-	PRP$
cord-029813-o2uzcuai	31	2	father	father	NN
cord-029813-o2uzcuai	31	3	was	be	VBD
cord-029813-o2uzcuai	31	4	diagnosed	diagnose	VBN
cord-029813-o2uzcuai	31	5	with	with	IN
cord-029813-o2uzcuai	31	6	COVID-19	COVID-19	NNP
cord-029813-o2uzcuai	31	7	on	on	IN
cord-029813-o2uzcuai	31	8	5	5	CD
cord-029813-o2uzcuai	31	9	February	February	NNP
cord-029813-o2uzcuai	31	10	and	and	CC
cord-029813-o2uzcuai	31	11	she	-PRON-	PRP
cord-029813-o2uzcuai	31	12	was	be	VBD
cord-029813-o2uzcuai	31	13	admitted	admit	VBN
cord-029813-o2uzcuai	31	14	to	to	IN
cord-029813-o2uzcuai	31	15	the	the	DT
cord-029813-o2uzcuai	31	16	hospital	hospital	NN
cord-029813-o2uzcuai	31	17	on	on	IN
cord-029813-o2uzcuai	31	18	7	7	CD
cord-029813-o2uzcuai	31	19	February	February	NNP
cord-029813-o2uzcuai	31	20	.	.	.
cord-029813-o2uzcuai	32	1	The	the	DT
cord-029813-o2uzcuai	32	2	case	case	NN
cord-029813-o2uzcuai	32	3	is	be	VBZ
cord-029813-o2uzcuai	32	4	of	of	IN
cord-029813-o2uzcuai	32	5	interest	interest	NN
cord-029813-o2uzcuai	32	6	because	because	IN
cord-029813-o2uzcuai	32	7	it	-PRON-	PRP
cord-029813-o2uzcuai	32	8	points	point	VBZ
cord-029813-o2uzcuai	32	9	out	out	RP
cord-029813-o2uzcuai	32	10	at	at	RB
cord-029813-o2uzcuai	32	11	least	least	RBS
cord-029813-o2uzcuai	32	12	two	two	CD
cord-029813-o2uzcuai	32	13	issues	issue	NNS
cord-029813-o2uzcuai	32	14	related	relate	VBN
cord-029813-o2uzcuai	32	15	to	to	IN
cord-029813-o2uzcuai	32	16	diagnostic	diagnostic	JJ
cord-029813-o2uzcuai	32	17	testing	testing	NN
cord-029813-o2uzcuai	32	18	.	.	.
cord-029813-o2uzcuai	33	1	First	first	RB
cord-029813-o2uzcuai	33	2	,	,	,
cord-029813-o2uzcuai	33	3	the	the	DT
cord-029813-o2uzcuai	33	4	SARS	SARS	NNP
cord-029813-o2uzcuai	33	5	-	-	HYPH
cord-029813-o2uzcuai	33	6	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	33	7	RT	RT	NNP
cord-029813-o2uzcuai	33	8	-	-	HYPH
cord-029813-o2uzcuai	33	9	PCR	PCR	NNP
cord-029813-o2uzcuai	33	10	is	be	VBZ
cord-029813-o2uzcuai	33	11	an	an	DT
cord-029813-o2uzcuai	33	12	imperfect	imperfect	JJ
cord-029813-o2uzcuai	33	13	test	test	NN
cord-029813-o2uzcuai	33	14	that	that	WDT
cord-029813-o2uzcuai	33	15	depends	depend	VBZ
cord-029813-o2uzcuai	33	16	on	on	IN
cord-029813-o2uzcuai	33	17	the	the	DT
cord-029813-o2uzcuai	33	18	type	type	NN
cord-029813-o2uzcuai	33	19	,	,	,
cord-029813-o2uzcuai	33	20	quality	quality	NN
cord-029813-o2uzcuai	33	21	and	and	CC
cord-029813-o2uzcuai	33	22	handling	handling	NN
cord-029813-o2uzcuai	33	23	of	of	IN
cord-029813-o2uzcuai	33	24	the	the	DT
cord-029813-o2uzcuai	33	25	sample	sample	NN
cord-029813-o2uzcuai	33	26	,	,	,
cord-029813-o2uzcuai	33	27	duration	duration	NN
cord-029813-o2uzcuai	33	28	and	and	CC
cord-029813-o2uzcuai	33	29	severity	severity	NN
cord-029813-o2uzcuai	33	30	of	of	IN
cord-029813-o2uzcuai	33	31	illness	illness	NN
cord-029813-o2uzcuai	33	32	and	and	CC
cord-029813-o2uzcuai	33	33	assay	assay	NN
cord-029813-o2uzcuai	33	34	performance	performance	NN
cord-029813-o2uzcuai	33	35	.	.	.
cord-029813-o2uzcuai	34	1	In	in	IN
cord-029813-o2uzcuai	34	2	general	general	JJ
cord-029813-o2uzcuai	34	3	,	,	,
cord-029813-o2uzcuai	34	4	lower	low	JJR
cord-029813-o2uzcuai	34	5	respiratory	respiratory	JJ
cord-029813-o2uzcuai	34	6	tract	tract	NN
cord-029813-o2uzcuai	34	7	samples	sample	NNS
cord-029813-o2uzcuai	34	8	have	have	VBP
cord-029813-o2uzcuai	34	9	higher	high	JJR
cord-029813-o2uzcuai	34	10	yields	yield	NNS
cord-029813-o2uzcuai	34	11	than	than	IN
cord-029813-o2uzcuai	34	12	upper	upper	JJ
cord-029813-o2uzcuai	34	13	respiratory	respiratory	JJ
cord-029813-o2uzcuai	34	14	tract	tract	NN
cord-029813-o2uzcuai	34	15	ones	one	NNS
cord-029813-o2uzcuai	34	16	[	[	-LRB-
cord-029813-o2uzcuai	34	17	4	4	CD
cord-029813-o2uzcuai	34	18	]	]	-RRB-
cord-029813-o2uzcuai	34	19	.	.	.
cord-029813-o2uzcuai	35	1	Second	second	RB
cord-029813-o2uzcuai	35	2	,	,	,
cord-029813-o2uzcuai	35	3	the	the	DT
cord-029813-o2uzcuai	35	4	low	low	JJ
cord-029813-o2uzcuai	35	5	viral	viral	JJ
cord-029813-o2uzcuai	35	6	burden	burden	NN
cord-029813-o2uzcuai	35	7	seen	see	VBN
cord-029813-o2uzcuai	35	8	in	in	IN
cord-029813-o2uzcuai	35	9	some	some	DT
cord-029813-o2uzcuai	35	10	patients	patient	NNS
cord-029813-o2uzcuai	35	11	in	in	IN
cord-029813-o2uzcuai	35	12	the	the	DT
cord-029813-o2uzcuai	35	13	upper	upper	JJ
cord-029813-o2uzcuai	35	14	respiratory	respiratory	JJ
cord-029813-o2uzcuai	35	15	tract	tract	NN
cord-029813-o2uzcuai	35	16	can	can	MD
cord-029813-o2uzcuai	35	17	make	make	VB
cord-029813-o2uzcuai	35	18	virologic	virologic	JJ
cord-029813-o2uzcuai	35	19	diagnoses	diagnosis	NNS
cord-029813-o2uzcuai	35	20	difficult	difficult	JJ
cord-029813-o2uzcuai	35	21	,	,	,
cord-029813-o2uzcuai	35	22	so	so	IN
cord-029813-o2uzcuai	35	23	that	that	IN
cord-029813-o2uzcuai	35	24	repeated	repeat	VBN
cord-029813-o2uzcuai	35	25	sampling	sampling	NN
cord-029813-o2uzcuai	35	26	of	of	IN
cord-029813-o2uzcuai	35	27	multiple	multiple	JJ
cord-029813-o2uzcuai	35	28	sites	site	NNS
cord-029813-o2uzcuai	35	29	,	,	,
cord-029813-o2uzcuai	35	30	testing	testing	NN
cord-029813-o2uzcuai	35	31	of	of	IN
cord-029813-o2uzcuai	35	32	lower	low	JJR
cord-029813-o2uzcuai	35	33	respiratory	respiratory	JJ
cord-029813-o2uzcuai	35	34	tract	tract	NN
cord-029813-o2uzcuai	35	35	secretions	secretion	NNS
cord-029813-o2uzcuai	35	36	,	,	,
cord-029813-o2uzcuai	35	37	and	and	CC
cord-029813-o2uzcuai	35	38	,	,	,
cord-029813-o2uzcuai	35	39	later	later	RB
cord-029813-o2uzcuai	35	40	in	in	IN
cord-029813-o2uzcuai	35	41	the	the	DT
cord-029813-o2uzcuai	35	42	course	course	NN
cord-029813-o2uzcuai	35	43	,	,	,
cord-029813-o2uzcuai	35	44	detection	detection	NN
cord-029813-o2uzcuai	35	45	of	of	IN
cord-029813-o2uzcuai	35	46	IgM	IgM	NNP
cord-029813-o2uzcuai	35	47	/	/	SYM
cord-029813-o2uzcuai	35	48	IgG	IgG	NNP
cord-029813-o2uzcuai	35	49	antibodies	antibody	NNS
cord-029813-o2uzcuai	35	50	may	may	MD
cord-029813-o2uzcuai	35	51	be	be	VB
cord-029813-o2uzcuai	35	52	necessary	necessary	JJ
cord-029813-o2uzcuai	35	53	.	.	.
cord-029813-o2uzcuai	36	1	Another	another	DT
cord-029813-o2uzcuai	36	2	point	point	NN
cord-029813-o2uzcuai	36	3	raised	raise	VBN
cord-029813-o2uzcuai	36	4	by	by	IN
cord-029813-o2uzcuai	36	5	the	the	DT
cord-029813-o2uzcuai	36	6	authors	author	NNS
cord-029813-o2uzcuai	36	7	is	be	VBZ
cord-029813-o2uzcuai	36	8	the	the	DT
cord-029813-o2uzcuai	36	9	importance	importance	NN
cord-029813-o2uzcuai	36	10	of	of	IN
cord-029813-o2uzcuai	36	11	the	the	DT
cord-029813-o2uzcuai	36	12	epidemiological	epidemiological	JJ
cord-029813-o2uzcuai	36	13	link	link	NN
cord-029813-o2uzcuai	36	14	,	,	,
cord-029813-o2uzcuai	36	15	in	in	IN
cord-029813-o2uzcuai	36	16	other	other	JJ
cord-029813-o2uzcuai	36	17	words	word	NNS
cord-029813-o2uzcuai	36	18	,	,	,
cord-029813-o2uzcuai	36	19	the	the	DT
cord-029813-o2uzcuai	36	20	likely	likely	JJ
cord-029813-o2uzcuai	36	21	exposure	exposure	NN
cord-029813-o2uzcuai	36	22	within	within	IN
cord-029813-o2uzcuai	36	23	her	-PRON-	PRP$
cord-029813-o2uzcuai	36	24	family	family	NN
cord-029813-o2uzcuai	36	25	,	,	,
cord-029813-o2uzcuai	36	26	in	in	IN
cord-029813-o2uzcuai	36	27	leading	lead	VBG
cord-029813-o2uzcuai	36	28	to	to	IN
cord-029813-o2uzcuai	36	29	prompt	prompt	JJ
cord-029813-o2uzcuai	36	30	intervention	intervention	NN
cord-029813-o2uzcuai	36	31	,	,	,
cord-029813-o2uzcuai	36	32	along	along	IN
cord-029813-o2uzcuai	36	33	with	with	IN
cord-029813-o2uzcuai	36	34	clinical	clinical	JJ
cord-029813-o2uzcuai	36	35	features	feature	NNS
cord-029813-o2uzcuai	36	36	and	and	CC
cord-029813-o2uzcuai	36	37	radiological	radiological	JJ
cord-029813-o2uzcuai	36	38	findings	finding	NNS
cord-029813-o2uzcuai	36	39	.	.	.
cord-029813-o2uzcuai	37	1	The	the	DT
cord-029813-o2uzcuai	37	2	patient	patient	NN
cord-029813-o2uzcuai	37	3	was	be	VBD
cord-029813-o2uzcuai	37	4	admitted	admit	VBN
cord-029813-o2uzcuai	37	5	quickly	quickly	RB
cord-029813-o2uzcuai	37	6	and	and	CC
cord-029813-o2uzcuai	37	7	started	start	VBD
cord-029813-o2uzcuai	37	8	on	on	IN
cord-029813-o2uzcuai	37	9	two	two	CD
cord-029813-o2uzcuai	37	10	putative	putative	JJ
cord-029813-o2uzcuai	37	11	antivirals	antiviral	NNS
cord-029813-o2uzcuai	37	12	on	on	IN
cord-029813-o2uzcuai	37	13	the	the	DT
cord-029813-o2uzcuai	37	14	same	same	JJ
cord-029813-o2uzcuai	37	15	day	day	NN
cord-029813-o2uzcuai	37	16	.	.	.
cord-029813-o2uzcuai	38	1	Whatever	whatever	WDT
cord-029813-o2uzcuai	38	2	the	the	DT
cord-029813-o2uzcuai	38	3	chosen	choose	VBN
cord-029813-o2uzcuai	38	4	strategy	strategy	NN
cord-029813-o2uzcuai	38	5	,	,	,
cord-029813-o2uzcuai	38	6	timely	timely	RB
cord-029813-o2uzcuai	38	7	antiviral	antiviral	JJ
cord-029813-o2uzcuai	38	8	and	and	CC
cord-029813-o2uzcuai	38	9	supportive	supportive	JJ
cord-029813-o2uzcuai	38	10	therapy	therapy	NN
cord-029813-o2uzcuai	38	11	is	be	VBZ
cord-029813-o2uzcuai	38	12	a	a	DT
cord-029813-o2uzcuai	38	13	major	major	JJ
cord-029813-o2uzcuai	38	14	element	element	NN
cord-029813-o2uzcuai	38	15	for	for	IN
cord-029813-o2uzcuai	38	16	improving	improve	VBG
cord-029813-o2uzcuai	38	17	outcomes	outcome	NNS
cord-029813-o2uzcuai	38	18	in	in	IN
cord-029813-o2uzcuai	38	19	SARS	SARS	NNP
cord-029813-o2uzcuai	38	20	-	-	HYPH
cord-029813-o2uzcuai	38	21	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	38	22	illness	illness	NN
cord-029813-o2uzcuai	38	23	.	.	.
cord-029813-o2uzcuai	39	1	In	in	IN
cord-029813-o2uzcuai	39	2	parallel	parallel	JJ
cord-029813-o2uzcuai	39	3	,	,	,
cord-029813-o2uzcuai	39	4	some	some	DT
cord-029813-o2uzcuai	39	5	biomarkers	biomarker	NNS
cord-029813-o2uzcuai	39	6	,	,	,
cord-029813-o2uzcuai	39	7	as	as	IN
cord-029813-o2uzcuai	39	8	illustrated	illustrate	VBN
cord-029813-o2uzcuai	39	9	in	in	IN
cord-029813-o2uzcuai	39	10	this	this	DT
cord-029813-o2uzcuai	39	11	patient	patient	NN
cord-029813-o2uzcuai	39	12	,	,	,
cord-029813-o2uzcuai	39	13	have	have	VBP
cord-029813-o2uzcuai	39	14	demonstrated	demonstrate	VBN
cord-029813-o2uzcuai	39	15	their	-PRON-	PRP$
cord-029813-o2uzcuai	39	16	value	value	NN
cord-029813-o2uzcuai	39	17	in	in	IN
cord-029813-o2uzcuai	39	18	evaluating	evaluate	VBG
cord-029813-o2uzcuai	39	19	the	the	DT
cord-029813-o2uzcuai	39	20	clinical	clinical	JJ
cord-029813-o2uzcuai	39	21	course	course	NN
cord-029813-o2uzcuai	39	22	of	of	IN
cord-029813-o2uzcuai	39	23	this	this	DT
cord-029813-o2uzcuai	39	24	infection	infection	NN
cord-029813-o2uzcuai	39	25	:	:	:
cord-029813-o2uzcuai	39	26	lymphocyte	lymphocyte	NN
cord-029813-o2uzcuai	39	27	count	count	NN
cord-029813-o2uzcuai	39	28	,	,	,
cord-029813-o2uzcuai	39	29	CD4	CD4	NNP
cord-029813-o2uzcuai	39	30	and	and	CC
cord-029813-o2uzcuai	39	31	CD8	CD8	NNP
cord-029813-o2uzcuai	39	32	population	population	NN
cord-029813-o2uzcuai	39	33	subsets	subset	NNS
cord-029813-o2uzcuai	39	34	,	,	,
cord-029813-o2uzcuai	39	35	LDH	LDH	NNP
cord-029813-o2uzcuai	39	36	and	and	CC
cord-029813-o2uzcuai	39	37	CRP	CRP	NNP
cord-029813-o2uzcuai	39	38	.	.	.
cord-029813-o2uzcuai	40	1	Monitoring	monitor	VBG
cord-029813-o2uzcuai	40	2	these	these	DT
cord-029813-o2uzcuai	40	3	laboratory	laboratory	NN
cord-029813-o2uzcuai	40	4	measures	measure	NNS
cord-029813-o2uzcuai	40	5	,	,	,
cord-029813-o2uzcuai	40	6	together	together	RB
cord-029813-o2uzcuai	40	7	with	with	IN
cord-029813-o2uzcuai	40	8	plasma	plasma	NN
cord-029813-o2uzcuai	40	9	D	d	NN
cord-029813-o2uzcuai	40	10	-	-	HYPH
cord-029813-o2uzcuai	40	11	dimer	dimer	NN
cord-029813-o2uzcuai	40	12	and	and	CC
cord-029813-o2uzcuai	40	13	IL-6	IL-6	NNP
cord-029813-o2uzcuai	40	14	levels	level	NNS
cord-029813-o2uzcuai	40	15	that	that	WDT
cord-029813-o2uzcuai	40	16	have	have	VBP
cord-029813-o2uzcuai	40	17	implications	implication	NNS
cord-029813-o2uzcuai	40	18	for	for	IN
cord-029813-o2uzcuai	40	19	treatment	treatment	NN
cord-029813-o2uzcuai	40	20	and	and	CC
cord-029813-o2uzcuai	40	21	prognosis	prognosis	NN
cord-029813-o2uzcuai	40	22	,	,	,
cord-029813-o2uzcuai	40	23	can	can	MD
cord-029813-o2uzcuai	40	24	prove	prove	VB
cord-029813-o2uzcuai	40	25	to	to	TO
cord-029813-o2uzcuai	40	26	be	be	VB
cord-029813-o2uzcuai	40	27	of	of	IN
cord-029813-o2uzcuai	40	28	help	help	NN
cord-029813-o2uzcuai	40	29	in	in	IN
cord-029813-o2uzcuai	40	30	clinical	clinical	JJ
cord-029813-o2uzcuai	40	31	management	management	NN
cord-029813-o2uzcuai	40	32	.	.	.
cord-029813-o2uzcuai	41	1	Li	Li	NNP
cord-029813-o2uzcuai	41	2	et	et	NNP
cord-029813-o2uzcuai	41	3	al	al	NNP
cord-029813-o2uzcuai	41	4	.	.	.
cord-029813-o2uzcuai	42	1	reported	report	VBN
cord-029813-o2uzcuai	42	2	,	,	,
cord-029813-o2uzcuai	42	3	both	both	CC
cord-029813-o2uzcuai	42	4	in	in	IN
cord-029813-o2uzcuai	42	5	a	a	DT
cord-029813-o2uzcuai	42	6	short	short	JJ
cord-029813-o2uzcuai	42	7	communication	communication	NN
cord-029813-o2uzcuai	42	8	[	[	-LRB-
cord-029813-o2uzcuai	42	9	5	5	CD
cord-029813-o2uzcuai	42	10	]	]	-RRB-
cord-029813-o2uzcuai	42	11	and	and	CC
cord-029813-o2uzcuai	42	12	in	in	IN
cord-029813-o2uzcuai	42	13	a	a	DT
cord-029813-o2uzcuai	42	14	special	special	JJ
cord-029813-o2uzcuai	42	15	report	report	NN
cord-029813-o2uzcuai	42	16	[	[	-LRB-
cord-029813-o2uzcuai	42	17	6	6	CD
cord-029813-o2uzcuai	42	18	]	]	-RRB-
cord-029813-o2uzcuai	42	19	,	,	,
cord-029813-o2uzcuai	42	20	some	some	DT
cord-029813-o2uzcuai	42	21	concern	concern	NN
cord-029813-o2uzcuai	42	22	on	on	IN
cord-029813-o2uzcuai	42	23	the	the	DT
cord-029813-o2uzcuai	42	24	application	application	NN
cord-029813-o2uzcuai	42	25	of	of	IN
cord-029813-o2uzcuai	42	26	genomic	genomic	JJ
cord-029813-o2uzcuai	42	27	evolutionary	evolutionary	JJ
cord-029813-o2uzcuai	42	28	theories	theory	NNS
cord-029813-o2uzcuai	42	29	to	to	IN
cord-029813-o2uzcuai	42	30	SARS	SARS	NNP
cord-029813-o2uzcuai	42	31	-	-	HYPH
cord-029813-o2uzcuai	42	32	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	42	33	.	.	.
cord-029813-o2uzcuai	43	1	The	the	DT
cord-029813-o2uzcuai	43	2	new	new	JJ
cord-029813-o2uzcuai	43	3	coronavirus	coronavirus	NN
cord-029813-o2uzcuai	43	4	SARS	SARS	NNP
cord-029813-o2uzcuai	43	5	-	-	HYPH
cord-029813-o2uzcuai	43	6	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	43	7	,	,	,
cord-029813-o2uzcuai	43	8	isolated	isolate	VBN
cord-029813-o2uzcuai	43	9	from	from	IN
cord-029813-o2uzcuai	43	10	humans	human	NNS
cord-029813-o2uzcuai	43	11	for	for	IN
cord-029813-o2uzcuai	43	12	the	the	DT
cord-029813-o2uzcuai	43	13	first	first	JJ
cord-029813-o2uzcuai	43	14	time	time	NN
cord-029813-o2uzcuai	43	15	in	in	IN
cord-029813-o2uzcuai	43	16	December	December	NNP
cord-029813-o2uzcuai	43	17	2019	2019	CD
cord-029813-o2uzcuai	43	18	,	,	,
cord-029813-o2uzcuai	43	19	appears	appear	VBZ
cord-029813-o2uzcuai	43	20	to	to	TO
cord-029813-o2uzcuai	43	21	have	have	VB
cord-029813-o2uzcuai	43	22	originated	originate	VBN
cord-029813-o2uzcuai	43	23	from	from	IN
cord-029813-o2uzcuai	43	24	bats	bat	NNS
cord-029813-o2uzcuai	43	25	.	.	.
cord-029813-o2uzcuai	44	1	This	this	DT
cord-029813-o2uzcuai	44	2	was	be	VBD
cord-029813-o2uzcuai	44	3	based	base	VBN
cord-029813-o2uzcuai	44	4	on	on	IN
cord-029813-o2uzcuai	44	5	genetic	genetic	JJ
cord-029813-o2uzcuai	44	6	analyses	analysis	NNS
cord-029813-o2uzcuai	44	7	and	and	CC
cord-029813-o2uzcuai	44	8	comparisons	comparison	NNS
cord-029813-o2uzcuai	44	9	with	with	IN
cord-029813-o2uzcuai	44	10	the	the	DT
cord-029813-o2uzcuai	44	11	sequences	sequence	NNS
cord-029813-o2uzcuai	44	12	of	of	IN
cord-029813-o2uzcuai	44	13	other	other	JJ
cord-029813-o2uzcuai	44	14	coronaviruses	coronaviruse	NNS
cord-029813-o2uzcuai	44	15	from	from	IN
cord-029813-o2uzcuai	44	16	different	different	JJ
cord-029813-o2uzcuai	44	17	animal	animal	NN
cord-029813-o2uzcuai	44	18	species	specie	NNS
cord-029813-o2uzcuai	44	19	.	.	.
cord-029813-o2uzcuai	45	1	Specifically	specifically	RB
cord-029813-o2uzcuai	45	2	,	,	,
cord-029813-o2uzcuai	45	3	two	two	CD
cord-029813-o2uzcuai	45	4	bat	bat	NN
cord-029813-o2uzcuai	45	5	coronaviruses	coronaviruse	NNS
cord-029813-o2uzcuai	45	6	share	share	VBP
cord-029813-o2uzcuai	45	7	88	88	CD
cord-029813-o2uzcuai	45	8	%	%	NN
cord-029813-o2uzcuai	45	9	of	of	IN
cord-029813-o2uzcuai	45	10	the	the	DT
cord-029813-o2uzcuai	45	11	genetic	genetic	JJ
cord-029813-o2uzcuai	45	12	sequence	sequence	NN
cord-029813-o2uzcuai	45	13	with	with	IN
cord-029813-o2uzcuai	45	14	that	that	DT
cord-029813-o2uzcuai	45	15	of	of	IN
cord-029813-o2uzcuai	45	16	SARS	SARS	NNP
cord-029813-o2uzcuai	45	17	-	-	HYPH
cord-029813-o2uzcuai	45	18	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	45	19	.	.	.
cord-029813-o2uzcuai	46	1	In	in	IN
cord-029813-o2uzcuai	46	2	comparison	comparison	NN
cord-029813-o2uzcuai	46	3	,	,	,
cord-029813-o2uzcuai	46	4	SARS	SARS	NNP
cord-029813-o2uzcuai	46	5	-	-	HYPH
cord-029813-o2uzcuai	46	6	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	46	7	shares	share	NNS
cord-029813-o2uzcuai	46	8	approximately	approximately	RB
cord-029813-o2uzcuai	46	9	79	79	CD
cord-029813-o2uzcuai	46	10	%	%	NN
cord-029813-o2uzcuai	46	11	genetic	genetic	JJ
cord-029813-o2uzcuai	46	12	sequence	sequence	NN
cord-029813-o2uzcuai	46	13	homology	homology	NN
cord-029813-o2uzcuai	46	14	with	with	IN
cord-029813-o2uzcuai	46	15	SARS	SARS	NNP
cord-029813-o2uzcuai	46	16	-	-	HYPH
cord-029813-o2uzcuai	46	17	CoV	CoV	NNP
cord-029813-o2uzcuai	46	18	and	and	CC
cord-029813-o2uzcuai	46	19	50	50	CD
cord-029813-o2uzcuai	46	20	%	%	NN
cord-029813-o2uzcuai	46	21	with	with	IN
cord-029813-o2uzcuai	46	22	MERS	MERS	NNP
cord-029813-o2uzcuai	46	23	-	-	HYPH
cord-029813-o2uzcuai	46	24	CoV.	CoV.	NNP
cord-029813-o2uzcuai	47	1	As	as	IN
cord-029813-o2uzcuai	47	2	with	with	IN
cord-029813-o2uzcuai	47	3	SARS	SARS	NNP
cord-029813-o2uzcuai	47	4	-	-	HYPH
cord-029813-o2uzcuai	47	5	CoV	CoV	NNP
cord-029813-o2uzcuai	47	6	and	and	CC
cord-029813-o2uzcuai	47	7	MERS	MERS	NNP
cord-029813-o2uzcuai	47	8	-	-	HYPH
cord-029813-o2uzcuai	47	9	CoV	CoV	NNP
cord-029813-o2uzcuai	47	10	,	,	,
cord-029813-o2uzcuai	47	11	it	-PRON-	PRP
cord-029813-o2uzcuai	47	12	is	be	VBZ
cord-029813-o2uzcuai	47	13	assumed	assume	VBN
cord-029813-o2uzcuai	47	14	that	that	IN
cord-029813-o2uzcuai	47	15	the	the	DT
cord-029813-o2uzcuai	47	16	transmission	transmission	NN
cord-029813-o2uzcuai	47	17	did	do	VBD
cord-029813-o2uzcuai	47	18	not	not	RB
cord-029813-o2uzcuai	47	19	occur	occur	VB
cord-029813-o2uzcuai	47	20	directly	directly	RB
cord-029813-o2uzcuai	47	21	from	from	IN
cord-029813-o2uzcuai	47	22	bats	bat	NNS
cord-029813-o2uzcuai	47	23	to	to	IN
cord-029813-o2uzcuai	47	24	humans	human	NNS
cord-029813-o2uzcuai	47	25	,	,	,
cord-029813-o2uzcuai	47	26	but	but	CC
cord-029813-o2uzcuai	47	27	that	that	IN
cord-029813-o2uzcuai	47	28	there	there	EX
cord-029813-o2uzcuai	47	29	could	could	MD
cord-029813-o2uzcuai	47	30	be	be	VB
cord-029813-o2uzcuai	47	31	another	another	DT
cord-029813-o2uzcuai	47	32	animal	animal	NN
cord-029813-o2uzcuai	47	33	yet	yet	RB
cord-029813-o2uzcuai	47	34	to	to	TO
cord-029813-o2uzcuai	47	35	be	be	VB
cord-029813-o2uzcuai	47	36	identified	identify	VBN
cord-029813-o2uzcuai	47	37	that	that	WDT
cord-029813-o2uzcuai	47	38	acted	act	VBD
cord-029813-o2uzcuai	47	39	as	as	IN
cord-029813-o2uzcuai	47	40	an	an	DT
cord-029813-o2uzcuai	47	41	intermediate	intermediate	JJ
cord-029813-o2uzcuai	47	42	host	host	NN
cord-029813-o2uzcuai	47	43	in	in	IN
cord-029813-o2uzcuai	47	44	transmission	transmission	NN
cord-029813-o2uzcuai	47	45	of	of	IN
cord-029813-o2uzcuai	47	46	the	the	DT
cord-029813-o2uzcuai	47	47	virus	virus	NN
cord-029813-o2uzcuai	47	48	to	to	IN
cord-029813-o2uzcuai	47	49	humans	human	NNS
cord-029813-o2uzcuai	47	50	.	.	.
cord-029813-o2uzcuai	48	1	From	from	IN
cord-029813-o2uzcuai	48	2	a	a	DT
cord-029813-o2uzcuai	48	3	molecular	molecular	JJ
cord-029813-o2uzcuai	48	4	point	point	NN
cord-029813-o2uzcuai	48	5	of	of	IN
cord-029813-o2uzcuai	48	6	view	view	NN
cord-029813-o2uzcuai	48	7	,	,	,
cord-029813-o2uzcuai	48	8	the	the	DT
cord-029813-o2uzcuai	48	9	fact	fact	NN
cord-029813-o2uzcuai	48	10	that	that	IN
cord-029813-o2uzcuai	48	11	coronaviruses	coronaviruse	NNS
cord-029813-o2uzcuai	48	12	can	can	MD
cord-029813-o2uzcuai	48	13	infect	infect	VB
cord-029813-o2uzcuai	48	14	different	different	JJ
cord-029813-o2uzcuai	48	15	animal	animal	NN
cord-029813-o2uzcuai	48	16	species	specie	NNS
cord-029813-o2uzcuai	48	17	and	and	CC
cord-029813-o2uzcuai	48	18	humans	human	NNS
cord-029813-o2uzcuai	48	19	can	can	MD
cord-029813-o2uzcuai	48	20	depend	depend	VB
cord-029813-o2uzcuai	48	21	on	on	IN
cord-029813-o2uzcuai	48	22	at	at	RB
cord-029813-o2uzcuai	48	23	least	least	RBS
cord-029813-o2uzcuai	48	24	two	two	CD
cord-029813-o2uzcuai	48	25	factors	factor	NNS
cord-029813-o2uzcuai	48	26	:	:	:
cord-029813-o2uzcuai	49	1	•	•	NNP
cord-029813-o2uzcuai	50	1	Mutations	mutation	NNS
cord-029813-o2uzcuai	50	2	that	that	WDT
cord-029813-o2uzcuai	50	3	lead	lead	VBP
cord-029813-o2uzcuai	50	4	to	to	IN
cord-029813-o2uzcuai	50	5	substitutions	substitution	NNS
cord-029813-o2uzcuai	50	6	in	in	IN
cord-029813-o2uzcuai	50	7	the	the	DT
cord-029813-o2uzcuai	50	8	virus	virus	NN
cord-029813-o2uzcuai	50	9	surface	surface	NN
cord-029813-o2uzcuai	50	10	protein	protein	NN
cord-029813-o2uzcuai	50	11	(	(	-LRB-
cord-029813-o2uzcuai	50	12	the	the	DT
cord-029813-o2uzcuai	50	13	spikes	spike	NNS
cord-029813-o2uzcuai	50	14	or	or	CC
cord-029813-o2uzcuai	50	15	'	'	``
cord-029813-o2uzcuai	50	16	spikes	spike	NNS
cord-029813-o2uzcuai	50	17	'	'	''
cord-029813-o2uzcuai	50	18	of	of	IN
cord-029813-o2uzcuai	50	19	the	the	DT
cord-029813-o2uzcuai	50	20	virus	virus	NN
cord-029813-o2uzcuai	50	21	)	)	-RRB-
cord-029813-o2uzcuai	50	22	that	that	WDT
cord-029813-o2uzcuai	50	23	favors	favor	VBZ
cord-029813-o2uzcuai	50	24	the	the	DT
cord-029813-o2uzcuai	50	25	attachment	attachment	NN
cord-029813-o2uzcuai	50	26	of	of	IN
cord-029813-o2uzcuai	50	27	the	the	DT
cord-029813-o2uzcuai	50	28	virus	virus	NN
cord-029813-o2uzcuai	50	29	to	to	IN
cord-029813-o2uzcuai	50	30	the	the	DT
cord-029813-o2uzcuai	50	31	cell	cell	NN
cord-029813-o2uzcuai	50	32	receptors	receptor	NNS
cord-029813-o2uzcuai	50	33	of	of	IN
cord-029813-o2uzcuai	50	34	the	the	DT
cord-029813-o2uzcuai	50	35	new	new	JJ
cord-029813-o2uzcuai	50	36	host	host	NN
cord-029813-o2uzcuai	50	37	and	and	CC
cord-029813-o2uzcuai	50	38	its	-PRON-	PRP$
cord-029813-o2uzcuai	50	39	entry	entry	NN
cord-029813-o2uzcuai	50	40	into	into	IN
cord-029813-o2uzcuai	50	41	the	the	DT
cord-029813-o2uzcuai	50	42	cell	cell	NN
cord-029813-o2uzcuai	50	43	to	to	TO
cord-029813-o2uzcuai	50	44	replicate	replicate	VB
cord-029813-o2uzcuai	50	45	.	.	.
cord-029813-o2uzcuai	51	1	•	•	NNP
cord-029813-o2uzcuai	52	1	Possibility	possibility	NN
cord-029813-o2uzcuai	52	2	of	of	IN
cord-029813-o2uzcuai	52	3	entry	entry	NN
cord-029813-o2uzcuai	52	4	into	into	IN
cord-029813-o2uzcuai	52	5	the	the	DT
cord-029813-o2uzcuai	52	6	cell	cell	NN
cord-029813-o2uzcuai	52	7	independent	independent	JJ
cord-029813-o2uzcuai	52	8	of	of	IN
cord-029813-o2uzcuai	52	9	the	the	DT
cord-029813-o2uzcuai	52	10	link	link	NN
cord-029813-o2uzcuai	52	11	between	between	IN
cord-029813-o2uzcuai	52	12	the	the	DT
cord-029813-o2uzcuai	52	13	viral	viral	JJ
cord-029813-o2uzcuai	52	14	protein	protein	NN
cord-029813-o2uzcuai	52	15	and	and	CC
cord-029813-o2uzcuai	52	16	receptor	receptor	NN
cord-029813-o2uzcuai	52	17	as	as	IN
cord-029813-o2uzcuai	52	18	an	an	DT
cord-029813-o2uzcuai	52	19	alternative	alternative	JJ
cord-029813-o2uzcuai	52	20	route	route	NN
cord-029813-o2uzcuai	52	21	for	for	IN
cord-029813-o2uzcuai	52	22	transmission	transmission	NN
cord-029813-o2uzcuai	52	23	between	between	IN
cord-029813-o2uzcuai	52	24	the	the	DT
cord-029813-o2uzcuai	52	25	different	different	JJ
cord-029813-o2uzcuai	52	26	animal	animal	NN
cord-029813-o2uzcuai	52	27	species	specie	NNS
cord-029813-o2uzcuai	52	28	and	and	CC
cord-029813-o2uzcuai	52	29	humans	human	NNS
cord-029813-o2uzcuai	52	30	.	.	.
cord-029813-o2uzcuai	53	1	The	the	DT
cord-029813-o2uzcuai	53	2	point	point	NN
cord-029813-o2uzcuai	53	3	raised	raise	VBN
cord-029813-o2uzcuai	53	4	by	by	IN
cord-029813-o2uzcuai	53	5	Li	Li	NNP
cord-029813-o2uzcuai	53	6	et	et	NNP
cord-029813-o2uzcuai	53	7	al	al	NNP
cord-029813-o2uzcuai	53	8	.	.	NNP
cord-029813-o2uzcuai	53	9	is	be	VBZ
cord-029813-o2uzcuai	53	10	that	that	IN
cord-029813-o2uzcuai	53	11	the	the	DT
cord-029813-o2uzcuai	53	12	application	application	NN
cord-029813-o2uzcuai	53	13	of	of	IN
cord-029813-o2uzcuai	53	14	evolutionary	evolutionary	JJ
cord-029813-o2uzcuai	53	15	theories	theory	NNS
cord-029813-o2uzcuai	53	16	to	to	IN
cord-029813-o2uzcuai	53	17	ssRNA	ssrna	VB
cord-029813-o2uzcuai	53	18	viruses	virus	NNS
cord-029813-o2uzcuai	53	19	-such	-such	.
cord-029813-o2uzcuai	54	1	as	as	IN
cord-029813-o2uzcuai	54	2	SARS	SARS	NNP
cord-029813-o2uzcuai	54	3	-	-	HYPH
cord-029813-o2uzcuai	54	4	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	55	1	-could	-could	:
cord-029813-o2uzcuai	55	2	overestimate	overestimate	VB
cord-029813-o2uzcuai	55	3	the	the	DT
cord-029813-o2uzcuai	55	4	divergence	divergence	NN
cord-029813-o2uzcuai	55	5	between	between	IN
cord-029813-o2uzcuai	55	6	a	a	DT
cord-029813-o2uzcuai	55	7	virus	virus	NN
cord-029813-o2uzcuai	55	8	isolated	isolate	VBN
cord-029813-o2uzcuai	55	9	in	in	IN
cord-029813-o2uzcuai	55	10	animal	animal	NN
cord-029813-o2uzcuai	55	11	species	specie	NNS
cord-029813-o2uzcuai	55	12	and	and	CC
cord-029813-o2uzcuai	55	13	humans	human	NNS
cord-029813-o2uzcuai	55	14	.	.	.
cord-029813-o2uzcuai	56	1	SARS	SARS	NNP
cord-029813-o2uzcuai	56	2	-	-	HYPH
cord-029813-o2uzcuai	56	3	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	56	4	is	be	VBZ
cord-029813-o2uzcuai	56	5	a	a	DT
cord-029813-o2uzcuai	56	6	positive	positive	JJ
cord-029813-o2uzcuai	56	7	-	-	HYPH
cord-029813-o2uzcuai	56	8	strand	strand	NN
cord-029813-o2uzcuai	56	9	RNA	RNA	NNP
cord-029813-o2uzcuai	56	10	virus	virus	NN
cord-029813-o2uzcuai	56	11	that	that	WDT
cord-029813-o2uzcuai	56	12	reproduces	reproduce	VBZ
cord-029813-o2uzcuai	56	13	its	-PRON-	PRP$
cord-029813-o2uzcuai	56	14	genomic	genomic	JJ
cord-029813-o2uzcuai	56	15	RNA	rna	NN
cord-029813-o2uzcuai	56	16	through	through	IN
cord-029813-o2uzcuai	56	17	the	the	DT
cord-029813-o2uzcuai	56	18	action	action	NN
cord-029813-o2uzcuai	56	19	of	of	IN
cord-029813-o2uzcuai	56	20	an	an	DT
cord-029813-o2uzcuai	56	21	RNA	RNA	NNP
cord-029813-o2uzcuai	56	22	dependent	dependent	JJ
cord-029813-o2uzcuai	56	23	RNA	RNA	NNP
cord-029813-o2uzcuai	56	24	polymerase	polymerase	NN
cord-029813-o2uzcuai	56	25	and	and	CC
cord-029813-o2uzcuai	56	26	does	do	VBZ
cord-029813-o2uzcuai	56	27	not	not	RB
cord-029813-o2uzcuai	56	28	have	have	VB
cord-029813-o2uzcuai	56	29	an	an	DT
cord-029813-o2uzcuai	56	30	intermediate	intermediate	JJ
cord-029813-o2uzcuai	56	31	DNA	dna	NN
cord-029813-o2uzcuai	56	32	genome	genome	NN
cord-029813-o2uzcuai	56	33	like	like	IN
cord-029813-o2uzcuai	56	34	HIV	HIV	NNP
cord-029813-o2uzcuai	56	35	.	.	.
cord-029813-o2uzcuai	57	1	Moreover	moreover	RB
cord-029813-o2uzcuai	57	2	,	,	,
cord-029813-o2uzcuai	57	3	RNA	RNA	NNP
cord-029813-o2uzcuai	57	4	viruses	virus	NNS
cord-029813-o2uzcuai	57	5	adapt	adapt	VBP
cord-029813-o2uzcuai	57	6	to	to	IN
cord-029813-o2uzcuai	57	7	the	the	DT
cord-029813-o2uzcuai	57	8	host	host	NN
cord-029813-o2uzcuai	57	9	expression	expression	NN
cord-029813-o2uzcuai	57	10	system	system	NN
cord-029813-o2uzcuai	57	11	,	,	,
cord-029813-o2uzcuai	57	12	in	in	IN
cord-029813-o2uzcuai	57	13	other	other	JJ
cord-029813-o2uzcuai	57	14	words	word	NNS
cord-029813-o2uzcuai	57	15	,	,	,
cord-029813-o2uzcuai	57	16	their	-PRON-	PRP$
cord-029813-o2uzcuai	57	17	codons	codon	NNS
cord-029813-o2uzcuai	57	18	adapt	adapt	VBP
cord-029813-o2uzcuai	57	19	to	to	IN
cord-029813-o2uzcuai	57	20	the	the	DT
cord-029813-o2uzcuai	57	21	host	host	NN
cord-029813-o2uzcuai	57	22	system	system	NN
cord-029813-o2uzcuai	57	23	they	-PRON-	PRP
cord-029813-o2uzcuai	57	24	are	be	VBP
cord-029813-o2uzcuai	57	25	infecting	infect	VBG
cord-029813-o2uzcuai	57	26	.	.	.
cord-029813-o2uzcuai	58	1	In	in	IN
cord-029813-o2uzcuai	58	2	detail	detail	NN
cord-029813-o2uzcuai	58	3	,	,	,
cord-029813-o2uzcuai	58	4	the	the	DT
cord-029813-o2uzcuai	58	5	authors	author	NNS
cord-029813-o2uzcuai	58	6	point	point	VBP
cord-029813-o2uzcuai	58	7	out	out	RP
cord-029813-o2uzcuai	58	8	that	that	IN
cord-029813-o2uzcuai	58	9	SARS	SARS	NNP
cord-029813-o2uzcuai	58	10	-	-	HYPH
cord-029813-o2uzcuai	58	11	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	58	12	and	and	CC
cord-029813-o2uzcuai	58	13	RaTG13	RaTG13	NNP
cord-029813-o2uzcuai	58	14	,	,	,
cord-029813-o2uzcuai	58	15	a	a	DT
cord-029813-o2uzcuai	58	16	bat	bat	NN
cord-029813-o2uzcuai	58	17	coronavirus	coronavirus	NN
cord-029813-o2uzcuai	58	18	,	,	,
cord-029813-o2uzcuai	58	19	were	be	VBD
cord-029813-o2uzcuai	58	20	previously	previously	RB
cord-029813-o2uzcuai	58	21	reported	report	VBN
cord-029813-o2uzcuai	58	22	to	to	TO
cord-029813-o2uzcuai	58	23	have	have	VB
cord-029813-o2uzcuai	58	24	17	17	CD
cord-029813-o2uzcuai	58	25	%	%	NN
cord-029813-o2uzcuai	58	26	synonymous	synonymous	JJ
cord-029813-o2uzcuai	58	27	changes	change	NNS
cord-029813-o2uzcuai	58	28	at	at	IN
cord-029813-o2uzcuai	58	29	neutral	neutral	JJ
cord-029813-o2uzcuai	58	30	sites	site	NNS
cord-029813-o2uzcuai	58	31	[	[	-LRB-
cord-029813-o2uzcuai	58	32	7	7	CD
cord-029813-o2uzcuai	58	33	]	]	-RRB-
cord-029813-o2uzcuai	58	34	.	.	.
cord-029813-o2uzcuai	59	1	Through	through	IN
cord-029813-o2uzcuai	59	2	the	the	DT
cord-029813-o2uzcuai	59	3	alignment	alignment	NN
cord-029813-o2uzcuai	59	4	of	of	IN
cord-029813-o2uzcuai	59	5	coding	code	VBG
cord-029813-o2uzcuai	59	6	sequences	sequence	NNS
cord-029813-o2uzcuai	59	7	of	of	IN
cord-029813-o2uzcuai	59	8	both	both	DT
cord-029813-o2uzcuai	59	9	viruses	virus	NNS
cord-029813-o2uzcuai	59	10	,	,	,
cord-029813-o2uzcuai	59	11	Li	Li	NNP
cord-029813-o2uzcuai	59	12	et	et	NNP
cord-029813-o2uzcuai	59	13	al	al	NNP
cord-029813-o2uzcuai	59	14	.	.	.
cord-029813-o2uzcuai	60	1	report	report	VB
cord-029813-o2uzcuai	60	2	that	that	IN
cord-029813-o2uzcuai	60	3	the	the	DT
cord-029813-o2uzcuai	60	4	RNA	RNA	NNP
cord-029813-o2uzcuai	60	5	modification	modification	NN
cord-029813-o2uzcuai	60	6	system	system	NN
cord-029813-o2uzcuai	60	7	in	in	IN
cord-029813-o2uzcuai	60	8	host	host	NN
cord-029813-o2uzcuai	60	9	cells	cell	NNS
cord-029813-o2uzcuai	60	10	might	may	MD
cord-029813-o2uzcuai	60	11	be	be	VB
cord-029813-o2uzcuai	60	12	the	the	DT
cord-029813-o2uzcuai	60	13	cause	cause	NN
cord-029813-o2uzcuai	60	14	of	of	IN
cord-029813-o2uzcuai	60	15	87	87	CD
cord-029813-o2uzcuai	60	16	%	%	NN
cord-029813-o2uzcuai	60	17	of	of	IN
cord-029813-o2uzcuai	60	18	the	the	DT
cord-029813-o2uzcuai	60	19	synonymous	synonymous	JJ
cord-029813-o2uzcuai	60	20	substitutions	substitution	NNS
cord-029813-o2uzcuai	60	21	between	between	IN
cord-029813-o2uzcuai	60	22	SARS	SARS	NNP
cord-029813-o2uzcuai	60	23	-	-	HYPH
cord-029813-o2uzcuai	60	24	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	60	25	and	and	CC
cord-029813-o2uzcuai	60	26	RaTG13	RaTG13	NNP
cord-029813-o2uzcuai	60	27	and	and	CC
cord-029813-o2uzcuai	60	28	conclude	conclude	VBP
cord-029813-o2uzcuai	60	29	that	that	IN
cord-029813-o2uzcuai	60	30	an	an	DT
cord-029813-o2uzcuai	60	31	overestimation	overestimation	NN
cord-029813-o2uzcuai	60	32	of	of	IN
cord-029813-o2uzcuai	60	33	virus	virus	NN
cord-029813-o2uzcuai	60	34	divergence	divergence	NN
cord-029813-o2uzcuai	60	35	is	be	VBZ
cord-029813-o2uzcuai	60	36	a	a	DT
cord-029813-o2uzcuai	60	37	risk	risk	NN
cord-029813-o2uzcuai	60	38	when	when	WRB
cord-029813-o2uzcuai	60	39	comparing	compare	VBG
cord-029813-o2uzcuai	60	40	two	two	CD
cord-029813-o2uzcuai	60	41	RNA	RNA	NNP
cord-029813-o2uzcuai	60	42	viruses	virus	NNS
cord-029813-o2uzcuai	60	43	[	[	-LRB-
cord-029813-o2uzcuai	60	44	5	5	CD
cord-029813-o2uzcuai	60	45	]	]	-RRB-
cord-029813-o2uzcuai	60	46	.	.	.
cord-029813-o2uzcuai	61	1	Li	Li	NNP
cord-029813-o2uzcuai	61	2	et	et	NNP
cord-029813-o2uzcuai	61	3	al	al	NNP
cord-029813-o2uzcuai	61	4	.	.	.
cord-029813-o2uzcuai	62	1	used	use	VBD
cord-029813-o2uzcuai	62	2	several	several	JJ
cord-029813-o2uzcuai	62	3	molecular	molecular	JJ
cord-029813-o2uzcuai	62	4	techniques	technique	NNS
cord-029813-o2uzcuai	62	5	to	to	TO
cord-029813-o2uzcuai	62	6	investigate	investigate	VB
cord-029813-o2uzcuai	62	7	protein	protein	NN
cord-029813-o2uzcuai	62	8	structures	structure	NNS
cord-029813-o2uzcuai	62	9	of	of	IN
cord-029813-o2uzcuai	62	10	SARS	SARS	NNP
cord-029813-o2uzcuai	62	11	-	-	HYPH
cord-029813-o2uzcuai	62	12	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	62	13	[	[	-LRB-
cord-029813-o2uzcuai	62	14	8	8	CD
cord-029813-o2uzcuai	62	15	]	]	-RRB-
cord-029813-o2uzcuai	62	16	.	.	.
cord-029813-o2uzcuai	63	1	The	the	DT
cord-029813-o2uzcuai	63	2	virus	virus	NN
cord-029813-o2uzcuai	63	3	itself	-PRON-	PRP
cord-029813-o2uzcuai	63	4	possesses	possess	VBZ
cord-029813-o2uzcuai	63	5	five	five	CD
cord-029813-o2uzcuai	63	6	keys	key	NNS
cord-029813-o2uzcuai	63	7	proteins	protein	NNS
cord-029813-o2uzcuai	63	8	:	:	:
cord-029813-o2uzcuai	63	9	open	open	JJ
cord-029813-o2uzcuai	63	10	-	-	HYPH
cord-029813-o2uzcuai	63	11	reading	read	VBG
cord-029813-o2uzcuai	63	12	frame	frame	NN
cord-029813-o2uzcuai	63	13	Lab	lab	NN
cord-029813-o2uzcuai	63	14	(	(	-LRB-
cord-029813-o2uzcuai	63	15	orfLab	orfLab	NNP
cord-029813-o2uzcuai	63	16	)	)	-RRB-
cord-029813-o2uzcuai	63	17	in	in	IN
cord-029813-o2uzcuai	63	18	the	the	DT
cord-029813-o2uzcuai	63	19	nonstructural	nonstructural	JJ
cord-029813-o2uzcuai	63	20	region	region	NN
cord-029813-o2uzcuai	63	21	and	and	CC
cord-029813-o2uzcuai	63	22	other	other	JJ
cord-029813-o2uzcuai	63	23	four	four	CD
cord-029813-o2uzcuai	63	24	structural	structural	JJ
cord-029813-o2uzcuai	63	25	proteins	protein	NNS
cord-029813-o2uzcuai	63	26	,	,	,
cord-029813-o2uzcuai	63	27	namely	namely	RB
cord-029813-o2uzcuai	63	28	S	s	NN
cord-029813-o2uzcuai	63	29	(	(	-LRB-
cord-029813-o2uzcuai	63	30	spike	spike	NN
cord-029813-o2uzcuai	63	31	)	)	-RRB-
cord-029813-o2uzcuai	63	32	,	,	,
cord-029813-o2uzcuai	63	33	M	M	NNP
cord-029813-o2uzcuai	63	34	(	(	-LRB-
cord-029813-o2uzcuai	63	35	membrane	membrane	NN
cord-029813-o2uzcuai	63	36	)	)	-RRB-
cord-029813-o2uzcuai	63	37	,	,	,
cord-029813-o2uzcuai	63	38	E	E	NNP
cord-029813-o2uzcuai	63	39	(	(	-LRB-
cord-029813-o2uzcuai	63	40	envelope	envelope	NN
cord-029813-o2uzcuai	63	41	)	)	-RRB-
cord-029813-o2uzcuai	63	42	and	and	CC
cord-029813-o2uzcuai	63	43	N	N	NNP
cord-029813-o2uzcuai	63	44	(	(	-LRB-
cord-029813-o2uzcuai	63	45	nucleoprotein	nucleoprotein	NNP
cord-029813-o2uzcuai	63	46	)	)	-RRB-
cord-029813-o2uzcuai	63	47	proteins	protein	NNS
cord-029813-o2uzcuai	63	48	.	.	.
cord-029813-o2uzcuai	64	1	The	the	DT
cord-029813-o2uzcuai	64	2	S	S	NNP
cord-029813-o2uzcuai	64	3	protein	protein	NN
cord-029813-o2uzcuai	64	4	is	be	VBZ
cord-029813-o2uzcuai	64	5	part	part	NN
cord-029813-o2uzcuai	64	6	of	of	IN
cord-029813-o2uzcuai	64	7	the	the	DT
cord-029813-o2uzcuai	64	8	shell	shell	NN
cord-029813-o2uzcuai	64	9	component	component	NN
cord-029813-o2uzcuai	64	10	and	and	CC
cord-029813-o2uzcuai	64	11	,	,	,
cord-029813-o2uzcuai	64	12	as	as	IN
cord-029813-o2uzcuai	64	13	indicated	indicate	VBN
cord-029813-o2uzcuai	64	14	above	above	RB
cord-029813-o2uzcuai	64	15	,	,	,
cord-029813-o2uzcuai	64	16	a	a	DT
cord-029813-o2uzcuai	64	17	pivotal	pivotal	JJ
cord-029813-o2uzcuai	64	18	component	component	NN
cord-029813-o2uzcuai	64	19	for	for	IN
cord-029813-o2uzcuai	64	20	cell	cell	NN
cord-029813-o2uzcuai	64	21	attachment	attachment	NN
cord-029813-o2uzcuai	64	22	.	.	.
cord-029813-o2uzcuai	65	1	This	this	DT
cord-029813-o2uzcuai	65	2	protein	protein	NN
cord-029813-o2uzcuai	65	3	is	be	VBZ
cord-029813-o2uzcuai	65	4	divided	divide	VBN
cord-029813-o2uzcuai	65	5	into	into	IN
cord-029813-o2uzcuai	65	6	two	two	CD
cord-029813-o2uzcuai	65	7	subunits	subunit	NNS
cord-029813-o2uzcuai	65	8	,	,	,
cord-029813-o2uzcuai	65	9	S1	s1	NN
cord-029813-o2uzcuai	65	10	and	and	CC
cord-029813-o2uzcuai	65	11	S2	s2	NN
cord-029813-o2uzcuai	65	12	:	:	:
cord-029813-o2uzcuai	65	13	S1	S1	NNP
cord-029813-o2uzcuai	65	14	contains	contain	VBZ
cord-029813-o2uzcuai	65	15	the	the	DT
cord-029813-o2uzcuai	65	16	receptor	receptor	NN
cord-029813-o2uzcuai	65	17	-	-	HYPH
cord-029813-o2uzcuai	65	18	binding	bind	VBG
cord-029813-o2uzcuai	65	19	domain	domain	NN
cord-029813-o2uzcuai	65	20	(	(	-LRB-
cord-029813-o2uzcuai	65	21	RBD	RBD	NNP
cord-029813-o2uzcuai	65	22	)	)	-RRB-
cord-029813-o2uzcuai	65	23	that	that	WDT
cord-029813-o2uzcuai	65	24	binds	bind	VBZ
cord-029813-o2uzcuai	65	25	to	to	IN
cord-029813-o2uzcuai	65	26	the	the	DT
cord-029813-o2uzcuai	65	27	angiotensin	angiotensin	NN
cord-029813-o2uzcuai	65	28	-	-	HYPH
cord-029813-o2uzcuai	65	29	converting	convert	VBG
cord-029813-o2uzcuai	65	30	enzyme	enzyme	NN
cord-029813-o2uzcuai	65	31	2	2	CD
cord-029813-o2uzcuai	66	1	(	(	-LRB-
cord-029813-o2uzcuai	66	2	ACE2	ACE2	NNP
cord-029813-o2uzcuai	66	3	)	)	-RRB-
cord-029813-o2uzcuai	66	4	cellular	cellular	JJ
cord-029813-o2uzcuai	66	5	receptor	receptor	NN
cord-029813-o2uzcuai	66	6	and	and	CC
cord-029813-o2uzcuai	66	7	S2	S2	NNP
cord-029813-o2uzcuai	66	8	mediates	mediate	VBZ
cord-029813-o2uzcuai	66	9	virus	virus	NN
cord-029813-o2uzcuai	66	10	-	-	HYPH
cord-029813-o2uzcuai	66	11	cell	cell	NN
cord-029813-o2uzcuai	66	12	membrane	membrane	NN
cord-029813-o2uzcuai	66	13	fusion	fusion	NN
cord-029813-o2uzcuai	66	14	.	.	.
cord-029813-o2uzcuai	67	1	The	the	DT
cord-029813-o2uzcuai	67	2	authors	author	NNS
cord-029813-o2uzcuai	67	3	obtained	obtain	VBD
cord-029813-o2uzcuai	67	4	the	the	DT
cord-029813-o2uzcuai	67	5	complete	complete	JJ
cord-029813-o2uzcuai	67	6	sequences	sequence	NNS
cord-029813-o2uzcuai	67	7	of	of	IN
cord-029813-o2uzcuai	67	8	SARS	SARS	NNP
cord-029813-o2uzcuai	67	9	-	-	HYPH
cord-029813-o2uzcuai	67	10	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	67	11	and	and	CC
cord-029813-o2uzcuai	67	12	six	six	CD
cord-029813-o2uzcuai	67	13	other	other	JJ
cord-029813-o2uzcuai	67	14	bat	bat	NN
cord-029813-o2uzcuai	67	15	coronaviruses	coronaviruse	NNS
cord-029813-o2uzcuai	67	16	.	.	.
cord-029813-o2uzcuai	68	1	They	-PRON-	PRP
cord-029813-o2uzcuai	68	2	applied	apply	VBD
cord-029813-o2uzcuai	68	3	multiple	multiple	JJ
cord-029813-o2uzcuai	68	4	techniques	technique	NNS
cord-029813-o2uzcuai	68	5	including	include	VBG
cord-029813-o2uzcuai	68	6	the	the	DT
cord-029813-o2uzcuai	68	7	analysis	analysis	NN
cord-029813-o2uzcuai	68	8	of	of	IN
cord-029813-o2uzcuai	68	9	structure	structure	NN
cord-029813-o2uzcuai	68	10	and	and	CC
cord-029813-o2uzcuai	68	11	,	,	,
cord-029813-o2uzcuai	68	12	most	most	RBS
cord-029813-o2uzcuai	68	13	interestingly	interestingly	RB
cord-029813-o2uzcuai	68	14	,	,	,
cord-029813-o2uzcuai	68	15	the	the	DT
cord-029813-o2uzcuai	68	16	back	back	JJ
cord-029813-o2uzcuai	68	17	mutation	mutation	NN
cord-029813-o2uzcuai	68	18	of	of	IN
cord-029813-o2uzcuai	68	19	some	some	DT
cord-029813-o2uzcuai	68	20	codon	codon	NN
cord-029813-o2uzcuai	68	21	substitutions	substitution	NNS
cord-029813-o2uzcuai	68	22	within	within	IN
cord-029813-o2uzcuai	68	23	the	the	DT
cord-029813-o2uzcuai	68	24	RBD	RBD	NNP
cord-029813-o2uzcuai	68	25	.	.	.
cord-029813-o2uzcuai	69	1	All	all	DT
cord-029813-o2uzcuai	69	2	SARS-	sars-	VBP
cord-029813-o2uzcuai	69	3	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	69	4	five	five	CD
cord-029813-o2uzcuai	69	5	key	key	JJ
cord-029813-o2uzcuai	69	6	proteins	protein	NNS
cord-029813-o2uzcuai	69	7	have	have	VBP
cord-029813-o2uzcuai	69	8	a	a	DT
cord-029813-o2uzcuai	69	9	large	large	JJ
cord-029813-o2uzcuai	69	10	homology	homology	NN
cord-029813-o2uzcuai	69	11	with	with	IN
cord-029813-o2uzcuai	69	12	SARS	SARS	NNP
cord-029813-o2uzcuai	69	13	-	-	HYPH
cord-029813-o2uzcuai	69	14	CoV	CoV	NNP
cord-029813-o2uzcuai	69	15	from	from	IN
cord-029813-o2uzcuai	69	16	bats	bat	NNS
cord-029813-o2uzcuai	69	17	,	,	,
cord-029813-o2uzcuai	69	18	although	although	IN
cord-029813-o2uzcuai	69	19	the	the	DT
cord-029813-o2uzcuai	69	20	lowest	low	JJS
cord-029813-o2uzcuai	69	21	homology	homology	NN
cord-029813-o2uzcuai	69	22	was	be	VBD
cord-029813-o2uzcuai	69	23	with	with	IN
cord-029813-o2uzcuai	69	24	the	the	DT
cord-029813-o2uzcuai	69	25	S	S	NNP
cord-029813-o2uzcuai	69	26	protein	protein	NN
cord-029813-o2uzcuai	69	27	,	,	,
cord-029813-o2uzcuai	69	28	which	which	WDT
cord-029813-o2uzcuai	69	29	showed	show	VBD
cord-029813-o2uzcuai	69	30	the	the	DT
cord-029813-o2uzcuai	69	31	highest	high	JJS
cord-029813-o2uzcuai	69	32	amino	amino	NN
cord-029813-o2uzcuai	69	33	acid	acid	NN
cord-029813-o2uzcuai	69	34	homology	homology	NN
cord-029813-o2uzcuai	69	35	with	with	IN
cord-029813-o2uzcuai	69	36	bat	bat	NN
cord-029813-o2uzcuai	69	37	SARS	SARS	NNP
cord-029813-o2uzcuai	69	38	RaTG13	RaTG13	NNP
cord-029813-o2uzcuai	69	39	reaching	reach	VBG
cord-029813-o2uzcuai	69	40	97.71	97.71	CD
cord-029813-o2uzcuai	69	41	%	%	NN
cord-029813-o2uzcuai	69	42	.	.	.
cord-029813-o2uzcuai	70	1	The	the	DT
cord-029813-o2uzcuai	70	2	authors	author	NNS
cord-029813-o2uzcuai	70	3	concluded	conclude	VBD
cord-029813-o2uzcuai	70	4	that	that	IN
cord-029813-o2uzcuai	70	5	it	-PRON-	PRP
cord-029813-o2uzcuai	70	6	is	be	VBZ
cord-029813-o2uzcuai	70	7	very	very	RB
cord-029813-o2uzcuai	70	8	likely	likely	JJ
cord-029813-o2uzcuai	70	9	that	that	IN
cord-029813-o2uzcuai	70	10	SARS	SARS	NNP
cord-029813-o2uzcuai	70	11	-	-	HYPH
cord-029813-o2uzcuai	70	12	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	70	13	developed	develop	VBD
cord-029813-o2uzcuai	70	14	from	from	IN
cord-029813-o2uzcuai	70	15	bat	bat	NN
cord-029813-o2uzcuai	70	16	SARS	SARS	NNP
cord-029813-o2uzcuai	70	17	CoV	CoV	NNP
cord-029813-o2uzcuai	70	18	given	give	VBN
cord-029813-o2uzcuai	70	19	this	this	DT
cord-029813-o2uzcuai	70	20	high	high	JJ
cord-029813-o2uzcuai	70	21	similarity	similarity	NN
cord-029813-o2uzcuai	70	22	.	.	.
cord-029813-o2uzcuai	71	1	Moreover	moreover	RB
cord-029813-o2uzcuai	71	2	,	,	,
cord-029813-o2uzcuai	71	3	the	the	DT
cord-029813-o2uzcuai	71	4	authors	author	NNS
cord-029813-o2uzcuai	71	5	backmutated	backmutate	VBD
cord-029813-o2uzcuai	71	6	the	the	DT
cord-029813-o2uzcuai	71	7	changed	change	VBN
cord-029813-o2uzcuai	71	8	three	three	CD
cord-029813-o2uzcuai	71	9	amino	amino	NN
cord-029813-o2uzcuai	71	10	acid	acid	NN
cord-029813-o2uzcuai	71	11	residues	residue	NNS
cord-029813-o2uzcuai	71	12	(	(	-LRB-
cord-029813-o2uzcuai	71	13	Glu	Glu	NNP
cord-029813-o2uzcuai	71	14	470	470	CD
cord-029813-o2uzcuai	71	15	,	,	,
cord-029813-o2uzcuai	72	1	Gln	Gln	NNP
cord-029813-o2uzcuai	72	2	484	484	CD
cord-029813-o2uzcuai	72	3	and	and	CC
cord-029813-o2uzcuai	72	4	Asn	Asn	NNP
cord-029813-o2uzcuai	72	5	487	487	CD
cord-029813-o2uzcuai	72	6	)	)	-RRB-
cord-029813-o2uzcuai	72	7	within	within	IN
cord-029813-o2uzcuai	72	8	the	the	DT
cord-029813-o2uzcuai	72	9	RBD	RBD	NNP
cord-029813-o2uzcuai	72	10	structure	structure	NN
cord-029813-o2uzcuai	72	11	and	and	CC
cord-029813-o2uzcuai	72	12	demonstrated	demonstrate	VBD
cord-029813-o2uzcuai	72	13	that	that	IN
cord-029813-o2uzcuai	72	14	the	the	DT
cord-029813-o2uzcuai	72	15	mutated	mutate	VBN
cord-029813-o2uzcuai	72	16	RBD	RBD	NNP
cord-029813-o2uzcuai	72	17	structure	structure	NN
cord-029813-o2uzcuai	72	18	has	have	VBZ
cord-029813-o2uzcuai	72	19	a	a	DT
cord-029813-o2uzcuai	72	20	stronger	strong	JJR
cord-029813-o2uzcuai	72	21	effect	effect	NN
cord-029813-o2uzcuai	72	22	on	on	IN
cord-029813-o2uzcuai	72	23	ACE2	ACE2	NNP
cord-029813-o2uzcuai	72	24	binding	binding	NN
cord-029813-o2uzcuai	72	25	.	.	.
cord-029813-o2uzcuai	73	1	This	this	DT
cord-029813-o2uzcuai	73	2	report	report	NN
cord-029813-o2uzcuai	73	3	adds	add	VBZ
cord-029813-o2uzcuai	73	4	to	to	IN
cord-029813-o2uzcuai	73	5	the	the	DT
cord-029813-o2uzcuai	73	6	considerable	considerable	JJ
cord-029813-o2uzcuai	73	7	data	datum	NNS
cord-029813-o2uzcuai	73	8	on	on	IN
cord-029813-o2uzcuai	73	9	the	the	DT
cord-029813-o2uzcuai	73	10	crystal	crystal	NN
cord-029813-o2uzcuai	73	11	structures	structure	NNS
cord-029813-o2uzcuai	73	12	and	and	CC
cord-029813-o2uzcuai	73	13	biophysical	biophysical	JJ
cord-029813-o2uzcuai	73	14	characterization	characterization	NN
cord-029813-o2uzcuai	73	15	of	of	IN
cord-029813-o2uzcuai	73	16	the	the	DT
cord-029813-o2uzcuai	73	17	ACE2	ACE2	NNP
cord-029813-o2uzcuai	73	18	interaction	interaction	NN
cord-029813-o2uzcuai	73	19	with	with	IN
cord-029813-o2uzcuai	73	20	the	the	DT
cord-029813-o2uzcuai	73	21	SARS	SARS	NNP
cord-029813-o2uzcuai	73	22	-	-	HYPH
cord-029813-o2uzcuai	73	23	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	73	24	RBD	RBD	NNP
cord-029813-o2uzcuai	73	25	that	that	WDT
cord-029813-o2uzcuai	73	26	have	have	VBP
cord-029813-o2uzcuai	73	27	been	be	VBN
cord-029813-o2uzcuai	73	28	reported	report	VBN
cord-029813-o2uzcuai	73	29	previously	previously	RB
cord-029813-o2uzcuai	73	30	,	,	,
cord-029813-o2uzcuai	73	31	including	include	VBG
cord-029813-o2uzcuai	73	32	receptor	receptor	NN
cord-029813-o2uzcuai	73	33	conformational	conformational	JJ
cord-029813-o2uzcuai	73	34	dynamics	dynamic	NNS
cord-029813-o2uzcuai	73	35	and	and	CC
cord-029813-o2uzcuai	73	36	other	other	JJ
cord-029813-o2uzcuai	73	37	analyses	analysis	NNS
cord-029813-o2uzcuai	73	38	highlighting	highlight	VBG
cord-029813-o2uzcuai	73	39	similarities	similarity	NNS
cord-029813-o2uzcuai	73	40	with	with	IN
cord-029813-o2uzcuai	73	41	the	the	DT
cord-029813-o2uzcuai	73	42	viruses	virus	NNS
cord-029813-o2uzcuai	73	43	from	from	IN
cord-029813-o2uzcuai	73	44	bats	bat	NNS
cord-029813-o2uzcuai	73	45	.	.	.
cord-029813-o2uzcuai	74	1	Hu	Hu	NNP
cord-029813-o2uzcuai	74	2	et	et	FW
cord-029813-o2uzcuai	74	3	al	al	NNP
cord-029813-o2uzcuai	74	4	.	.	.
cord-029813-o2uzcuai	75	1	[	[	-LRB-
cord-029813-o2uzcuai	75	2	9	9	CD
cord-029813-o2uzcuai	75	3	]	]	-RRB-
cord-029813-o2uzcuai	75	4	have	have	VBP
cord-029813-o2uzcuai	75	5	used	use	VBN
cord-029813-o2uzcuai	75	6	a	a	DT
cord-029813-o2uzcuai	75	7	molecular	molecular	JJ
cord-029813-o2uzcuai	75	8	docking	docking	NN
cord-029813-o2uzcuai	75	9	software	software	NN
cord-029813-o2uzcuai	75	10	program	program	NN
cord-029813-o2uzcuai	75	11	to	to	TO
cord-029813-o2uzcuai	75	12	screen	screen	VB
cord-029813-o2uzcuai	75	13	109	109	CD
cord-029813-o2uzcuai	75	14	plant	plant	NN
cord-029813-o2uzcuai	75	15	-	-	HYPH
cord-029813-o2uzcuai	75	16	derived	derive	VBN
cord-029813-o2uzcuai	75	17	chemical	chemical	NN
cord-029813-o2uzcuai	75	18	agents	agent	NNS
cord-029813-o2uzcuai	75	19	for	for	IN
cord-029813-o2uzcuai	75	20	their	-PRON-	PRP$
cord-029813-o2uzcuai	75	21	ability	ability	NN
cord-029813-o2uzcuai	75	22	to	to	TO
cord-029813-o2uzcuai	75	23	dock	dock	VB
cord-029813-o2uzcuai	75	24	with	with	IN
cord-029813-o2uzcuai	75	25	the	the	DT
cord-029813-o2uzcuai	75	26	SARS	SARS	NNP
cord-029813-o2uzcuai	75	27	-	-	HYPH
cord-029813-o2uzcuai	75	28	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	75	29	main	main	JJ
cord-029813-o2uzcuai	75	30	protease	protease	NN
cord-029813-o2uzcuai	75	31	(	(	-LRB-
cord-029813-o2uzcuai	75	32	Mpro	Mpro	NNP
cord-029813-o2uzcuai	75	33	)	)	-RRB-
cord-029813-o2uzcuai	75	34	.	.	.
cord-029813-o2uzcuai	76	1	As	as	IN
cord-029813-o2uzcuai	76	2	they	-PRON-	PRP
cord-029813-o2uzcuai	76	3	point	point	VBP
cord-029813-o2uzcuai	76	4	out	out	RP
cord-029813-o2uzcuai	76	5	in	in	IN
cord-029813-o2uzcuai	76	6	this	this	DT
cord-029813-o2uzcuai	76	7	Research	Research	NNP
cord-029813-o2uzcuai	76	8	Article	Article	NNP
cord-029813-o2uzcuai	76	9	,	,	,
cord-029813-o2uzcuai	76	10	the	the	DT
cord-029813-o2uzcuai	76	11	recent	recent	JJ
cord-029813-o2uzcuai	76	12	characterization	characterization	NN
cord-029813-o2uzcuai	76	13	of	of	IN
cord-029813-o2uzcuai	76	14	the	the	DT
cord-029813-o2uzcuai	76	15	crystal	crystal	JJ
cord-029813-o2uzcuai	76	16	structure	structure	NN
cord-029813-o2uzcuai	76	17	of	of	IN
cord-029813-o2uzcuai	76	18	Mpro	Mpro	NNP
cord-029813-o2uzcuai	76	19	and	and	CC
cord-029813-o2uzcuai	76	20	its	-PRON-	PRP$
cord-029813-o2uzcuai	76	21	high	high	JJ
cord-029813-o2uzcuai	76	22	degree	degree	NN
cord-029813-o2uzcuai	76	23	of	of	IN
cord-029813-o2uzcuai	76	24	conservation	conservation	NN
cord-029813-o2uzcuai	76	25	across	across	IN
cord-029813-o2uzcuai	76	26	coronaviruses	coronaviruse	NNS
cord-029813-o2uzcuai	76	27	makes	make	VBZ
cord-029813-o2uzcuai	76	28	it	-PRON-	PRP
cord-029813-o2uzcuai	76	29	an	an	DT
cord-029813-o2uzcuai	76	30	attractive	attractive	JJ
cord-029813-o2uzcuai	76	31	target	target	NN
cord-029813-o2uzcuai	76	32	for	for	IN
cord-029813-o2uzcuai	76	33	drug	drug	NN
cord-029813-o2uzcuai	76	34	discovery	discovery	NN
cord-029813-o2uzcuai	76	35	.	.	.
cord-029813-o2uzcuai	77	1	They	-PRON-	PRP
cord-029813-o2uzcuai	77	2	determined	determine	VBD
cord-029813-o2uzcuai	77	3	that	that	IN
cord-029813-o2uzcuai	77	4	the	the	DT
cord-029813-o2uzcuai	77	5	flavonoid	flavonoid	NN
cord-029813-o2uzcuai	77	6	rutin	rutin	NN
cord-029813-o2uzcuai	77	7	fits	fit	VBZ
cord-029813-o2uzcuai	77	8	well	well	RB
cord-029813-o2uzcuai	77	9	into	into	IN
cord-029813-o2uzcuai	77	10	the	the	DT
cord-029813-o2uzcuai	77	11	Mpro	Mpro	NNP
cord-029813-o2uzcuai	77	12	substrate	substrate	NN
cord-029813-o2uzcuai	77	13	-	-	HYPH
cord-029813-o2uzcuai	77	14	binding	bind	VBG
cord-029813-o2uzcuai	77	15	pocket	pocket	NN
cord-029813-o2uzcuai	77	16	and	and	CC
cord-029813-o2uzcuai	77	17	,	,	,
cord-029813-o2uzcuai	77	18	in	in	IN
cord-029813-o2uzcuai	77	19	addition	addition	NN
cord-029813-o2uzcuai	77	20	,	,	,
cord-029813-o2uzcuai	77	21	interacts	interact	VBZ
cord-029813-o2uzcuai	77	22	with	with	IN
cord-029813-o2uzcuai	77	23	pockets	pocket	NNS
cord-029813-o2uzcuai	77	24	in	in	IN
cord-029813-o2uzcuai	77	25	the	the	DT
cord-029813-o2uzcuai	77	26	toll	toll	NN
cord-029813-o2uzcuai	77	27	-	-	HYPH
cord-029813-o2uzcuai	77	28	like	like	JJ
cord-029813-o2uzcuai	77	29	receptors	receptor	NNS
cord-029813-o2uzcuai	77	30	(	(	-LRB-
cord-029813-o2uzcuai	77	31	TLRs	TLRs	NNP
cord-029813-o2uzcuai	77	32	)	)	-RRB-
cord-029813-o2uzcuai	77	33	,	,	,
cord-029813-o2uzcuai	77	34	TLR2	TLR2	NNP
cord-029813-o2uzcuai	77	35	,	,	,
cord-029813-o2uzcuai	77	36	TLR6	TLR6	NNP
cord-029813-o2uzcuai	77	37	and	and	CC
cord-029813-o2uzcuai	77	38	TLR7	TLR7	NNP
cord-029813-o2uzcuai	77	39	.	.	.
cord-029813-o2uzcuai	78	1	The	the	DT
cord-029813-o2uzcuai	78	2	finding	finding	NN
cord-029813-o2uzcuai	78	3	that	that	IN
cord-029813-o2uzcuai	78	4	remdesivir	remdesivir	NNP
cord-029813-o2uzcuai	78	5	,	,	,
cord-029813-o2uzcuai	78	6	which	which	WDT
cord-029813-o2uzcuai	78	7	targets	target	VBZ
cord-029813-o2uzcuai	78	8	the	the	DT
cord-029813-o2uzcuai	78	9	viral	viral	JJ
cord-029813-o2uzcuai	78	10	RNA	rna	NN
cord-029813-o2uzcuai	78	11	-	-	HYPH
cord-029813-o2uzcuai	78	12	dependent	dependent	JJ
cord-029813-o2uzcuai	78	13	RNA	RNA	NNP
cord-029813-o2uzcuai	78	14	polymerases	polymerase	NNS
cord-029813-o2uzcuai	78	15	of	of	IN
cord-029813-o2uzcuai	78	16	coronaviruses	coronaviruse	NNS
cord-029813-o2uzcuai	78	17	and	and	CC
cord-029813-o2uzcuai	78	18	several	several	JJ
cord-029813-o2uzcuai	78	19	other	other	JJ
cord-029813-o2uzcuai	78	20	RNA	RNA	NNP
cord-029813-o2uzcuai	78	21	virus	virus	NN
cord-029813-o2uzcuai	78	22	families	family	NNS
cord-029813-o2uzcuai	78	23	,	,	,
cord-029813-o2uzcuai	78	24	also	also	RB
cord-029813-o2uzcuai	78	25	proved	prove	VBD
cord-029813-o2uzcuai	78	26	to	to	TO
cord-029813-o2uzcuai	78	27	be	be	VB
cord-029813-o2uzcuai	78	28	positive	positive	JJ
cord-029813-o2uzcuai	78	29	in	in	IN
cord-029813-o2uzcuai	78	30	the	the	DT
cord-029813-o2uzcuai	78	31	Mpro	Mpro	NNP
cord-029813-o2uzcuai	78	32	docking	docking	NN
cord-029813-o2uzcuai	78	33	model	model	NN
cord-029813-o2uzcuai	78	34	raises	raise	VBZ
cord-029813-o2uzcuai	78	35	some	some	DT
cord-029813-o2uzcuai	78	36	questions	question	NNS
cord-029813-o2uzcuai	78	37	about	about	IN
cord-029813-o2uzcuai	78	38	its	-PRON-	PRP$
cord-029813-o2uzcuai	78	39	specificity	specificity	NN
cord-029813-o2uzcuai	78	40	.	.	.
cord-029813-o2uzcuai	79	1	The	the	DT
cord-029813-o2uzcuai	79	2	nature	nature	NN
cord-029813-o2uzcuai	79	3	of	of	IN
cord-029813-o2uzcuai	79	4	the	the	DT
cord-029813-o2uzcuai	79	5	interactions	interaction	NNS
cord-029813-o2uzcuai	79	6	with	with	IN
cord-029813-o2uzcuai	79	7	the	the	DT
cord-029813-o2uzcuai	79	8	TLRs	TLRs	NNPS
cord-029813-o2uzcuai	79	9	,	,	,
cord-029813-o2uzcuai	79	10	whether	whether	IN
cord-029813-o2uzcuai	79	11	stimulatory	stimulatory	JJ
cord-029813-o2uzcuai	79	12	or	or	CC
cord-029813-o2uzcuai	79	13	inhibitory	inhibitory	JJ
cord-029813-o2uzcuai	79	14	of	of	IN
cord-029813-o2uzcuai	79	15	proinflammatory	proinflammatory	JJ
cord-029813-o2uzcuai	79	16	responses	response	NNS
cord-029813-o2uzcuai	79	17	and	and	CC
cord-029813-o2uzcuai	79	18	antiviral	antiviral	JJ
cord-029813-o2uzcuai	79	19	effects	effect	NNS
cord-029813-o2uzcuai	79	20	,	,	,
cord-029813-o2uzcuai	79	21	are	be	VBP
cord-029813-o2uzcuai	79	22	unclear	unclear	JJ
cord-029813-o2uzcuai	79	23	from	from	IN
cord-029813-o2uzcuai	79	24	the	the	DT
cord-029813-o2uzcuai	79	25	report	report	NN
cord-029813-o2uzcuai	79	26	.	.	.
cord-029813-o2uzcuai	80	1	The	the	DT
cord-029813-o2uzcuai	80	2	authors	author	NNS
cord-029813-o2uzcuai	80	3	went	go	VBD
cord-029813-o2uzcuai	80	4	on	on	RP
cord-029813-o2uzcuai	80	5	to	to	TO
cord-029813-o2uzcuai	80	6	assess	assess	VB
cord-029813-o2uzcuai	80	7	host	host	NN
cord-029813-o2uzcuai	80	8	target	target	NN
cord-029813-o2uzcuai	80	9	genes	gene	NNS
cord-029813-o2uzcuai	80	10	of	of	IN
cord-029813-o2uzcuai	80	11	rutin	rutin	NN
cord-029813-o2uzcuai	80	12	by	by	IN
cord-029813-o2uzcuai	80	13	another	another	DT
cord-029813-o2uzcuai	80	14	modeling	modeling	NN
cord-029813-o2uzcuai	80	15	system	system	NN
cord-029813-o2uzcuai	80	16	and	and	CC
cord-029813-o2uzcuai	80	17	found	find	VBD
cord-029813-o2uzcuai	80	18	multiple	multiple	JJ
cord-029813-o2uzcuai	80	19	hits	hit	NNS
cord-029813-o2uzcuai	80	20	involving	involve	VBG
cord-029813-o2uzcuai	80	21	cellular	cellular	JJ
cord-029813-o2uzcuai	80	22	functions	function	NNS
cord-029813-o2uzcuai	80	23	,	,	,
cord-029813-o2uzcuai	80	24	some	some	DT
cord-029813-o2uzcuai	80	25	of	of	IN
cord-029813-o2uzcuai	80	26	which	which	WDT
cord-029813-o2uzcuai	80	27	are	be	VBP
cord-029813-o2uzcuai	80	28	involved	involve	VBN
cord-029813-o2uzcuai	80	29	with	with	IN
cord-029813-o2uzcuai	80	30	inflammation	inflammation	NN
cord-029813-o2uzcuai	80	31	.	.	.
cord-029813-o2uzcuai	81	1	The	the	DT
cord-029813-o2uzcuai	81	2	authors	author	NNS
cord-029813-o2uzcuai	81	3	speculate	speculate	VBP
cord-029813-o2uzcuai	81	4	that	that	IN
cord-029813-o2uzcuai	81	5	rutin	rutin	NN
cord-029813-o2uzcuai	81	6	might	may	MD
cord-029813-o2uzcuai	81	7	have	have	VB
cord-029813-o2uzcuai	81	8	the	the	DT
cord-029813-o2uzcuai	81	9	potential	potential	NN
cord-029813-o2uzcuai	81	10	to	to	TO
cord-029813-o2uzcuai	81	11	provide	provide	VB
cord-029813-o2uzcuai	81	12	both	both	DT
cord-029813-o2uzcuai	81	13	antiviral	antiviral	JJ
cord-029813-o2uzcuai	81	14	and	and	CC
cord-029813-o2uzcuai	81	15	antiinflammatory	antiinflammatory	JJ
cord-029813-o2uzcuai	81	16	effects	effect	NNS
cord-029813-o2uzcuai	81	17	.	.	.
cord-029813-o2uzcuai	82	1	While	while	IN
cord-029813-o2uzcuai	82	2	it	-PRON-	PRP
cord-029813-o2uzcuai	82	3	is	be	VBZ
cord-029813-o2uzcuai	82	4	clear	clear	JJ
cord-029813-o2uzcuai	82	5	that	that	IN
cord-029813-o2uzcuai	82	6	this	this	DT
cord-029813-o2uzcuai	82	7	phytochemical	phytochemical	NNP
cord-029813-o2uzcuai	82	8	has	have	VBZ
cord-029813-o2uzcuai	82	9	multiple	multiple	JJ
cord-029813-o2uzcuai	82	10	pharmacological	pharmacological	JJ
cord-029813-o2uzcuai	82	11	activities	activity	NNS
cord-029813-o2uzcuai	82	12	,	,	,
cord-029813-o2uzcuai	82	13	as	as	IN
cord-029813-o2uzcuai	82	14	reviewed	review	VBN
cord-029813-o2uzcuai	82	15	previously	previously	RB
cord-029813-o2uzcuai	82	16	[	[	-LRB-
cord-029813-o2uzcuai	82	17	10	10	CD
cord-029813-o2uzcuai	82	18	]	]	-RRB-
cord-029813-o2uzcuai	82	19	,	,	,
cord-029813-o2uzcuai	82	20	this	this	DT
cord-029813-o2uzcuai	82	21	in	in	IN
cord-029813-o2uzcuai	82	22	silico	silico	NN
cord-029813-o2uzcuai	82	23	report	report	NN
cord-029813-o2uzcuai	82	24	does	do	VBZ
cord-029813-o2uzcuai	82	25	not	not	RB
cord-029813-o2uzcuai	82	26	provide	provide	VB
cord-029813-o2uzcuai	82	27	biologic	biologic	JJ
cord-029813-o2uzcuai	82	28	data	datum	NNS
cord-029813-o2uzcuai	82	29	on	on	IN
cord-029813-o2uzcuai	82	30	rutin	rutin	NN
cord-029813-o2uzcuai	82	31	's	's	POS
cord-029813-o2uzcuai	82	32	possible	possible	JJ
cord-029813-o2uzcuai	82	33	effects	effect	NNS
cord-029813-o2uzcuai	82	34	in	in	IN
cord-029813-o2uzcuai	82	35	SARS	SARS	NNP
cord-029813-o2uzcuai	82	36	-	-	HYPH
cord-029813-o2uzcuai	82	37	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	82	38	infection	infection	NN
cord-029813-o2uzcuai	82	39	.	.	.
cord-029813-o2uzcuai	83	1	Tan	Tan	NNP
cord-029813-o2uzcuai	83	2	et	et	FW
cord-029813-o2uzcuai	83	3	al	al	NNP
cord-029813-o2uzcuai	83	4	.	.	.
cord-029813-o2uzcuai	84	1	discuss	discuss	VB
cord-029813-o2uzcuai	84	2	the	the	DT
cord-029813-o2uzcuai	84	3	critical	critical	JJ
cord-029813-o2uzcuai	84	4	public	public	JJ
cord-029813-o2uzcuai	84	5	health	health	NN
cord-029813-o2uzcuai	84	6	issue	issue	NN
cord-029813-o2uzcuai	84	7	of	of	IN
cord-029813-o2uzcuai	84	8	the	the	DT
cord-029813-o2uzcuai	84	9	extent	extent	NN
cord-029813-o2uzcuai	84	10	to	to	TO
cord-029813-o2uzcuai	84	11	which	which	WDT
cord-029813-o2uzcuai	84	12	asymptomatically	asymptomatically	RB
cord-029813-o2uzcuai	84	13	infected	infect	VBN
cord-029813-o2uzcuai	84	14	persons	person	NNS
cord-029813-o2uzcuai	84	15	are	be	VBP
cord-029813-o2uzcuai	84	16	transmitting	transmit	VBG
cord-029813-o2uzcuai	84	17	SARS	SARS	NNP
cord-029813-o2uzcuai	84	18	-	-	HYPH
cord-029813-o2uzcuai	84	19	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	84	20	to	to	IN
cord-029813-o2uzcuai	84	21	others	other	NNS
cord-029813-o2uzcuai	84	22	and	and	CC
cord-029813-o2uzcuai	84	23	contrast	contrast	VB
cord-029813-o2uzcuai	84	24	the	the	DT
cord-029813-o2uzcuai	84	25	currently	currently	RB
cord-029813-o2uzcuai	84	26	available	available	JJ
cord-029813-o2uzcuai	84	27	data	datum	NNS
cord-029813-o2uzcuai	84	28	with	with	IN
cord-029813-o2uzcuai	84	29	the	the	DT
cord-029813-o2uzcuai	84	30	epidemiologic	epidemiologic	JJ
cord-029813-o2uzcuai	84	31	findings	finding	NNS
cord-029813-o2uzcuai	84	32	in	in	IN
cord-029813-o2uzcuai	84	33	SARS	SARS	NNP
cord-029813-o2uzcuai	84	34	and	and	CC
cord-029813-o2uzcuai	84	35	MERS	MERS	NNP
cord-029813-o2uzcuai	84	36	[	[	-LRB-
cord-029813-o2uzcuai	84	37	11	11	CD
cord-029813-o2uzcuai	84	38	]	]	-RRB-
cord-029813-o2uzcuai	84	39	.	.	.
cord-029813-o2uzcuai	85	1	Detection	detection	NN
cord-029813-o2uzcuai	85	2	of	of	IN
cord-029813-o2uzcuai	85	3	relatively	relatively	RB
cord-029813-o2uzcuai	85	4	high	high	JJ
cord-029813-o2uzcuai	85	5	SARS	SARS	NNP
cord-029813-o2uzcuai	85	6	-	-	HYPH
cord-029813-o2uzcuai	85	7	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	85	8	RNA	RNA	NNP
cord-029813-o2uzcuai	85	9	loads	load	NNS
cord-029813-o2uzcuai	85	10	in	in	IN
cord-029813-o2uzcuai	85	11	upper	upper	JJ
cord-029813-o2uzcuai	85	12	respiratory	respiratory	JJ
cord-029813-o2uzcuai	85	13	tract	tract	NN
cord-029813-o2uzcuai	85	14	samples	sample	NNS
cord-029813-o2uzcuai	85	15	has	have	VBZ
cord-029813-o2uzcuai	85	16	been	be	VBN
cord-029813-o2uzcuai	85	17	reported	report	VBN
cord-029813-o2uzcuai	85	18	in	in	IN
cord-029813-o2uzcuai	85	19	both	both	DT
cord-029813-o2uzcuai	85	20	presymptomatic	presymptomatic	JJ
cord-029813-o2uzcuai	85	21	(	(	-LRB-
cord-029813-o2uzcuai	85	22	late	late	JJ
cord-029813-o2uzcuai	85	23	incubation	incubation	NN
cord-029813-o2uzcuai	85	24	period	period	NN
cord-029813-o2uzcuai	85	25	)	)	-RRB-
cord-029813-o2uzcuai	85	26	and	and	CC
cord-029813-o2uzcuai	85	27	truly	truly	RB
cord-029813-o2uzcuai	85	28	asymptomatic	asymptomatic	JJ
cord-029813-o2uzcuai	85	29	infected	infected	JJ
cord-029813-o2uzcuai	85	30	persons	person	NNS
cord-029813-o2uzcuai	85	31	.	.	.
cord-029813-o2uzcuai	86	1	The	the	DT
cord-029813-o2uzcuai	86	2	proportion	proportion	NN
cord-029813-o2uzcuai	86	3	of	of	IN
cord-029813-o2uzcuai	86	4	asymptomatic	asymptomatic	JJ
cord-029813-o2uzcuai	86	5	infections	infection	NNS
cord-029813-o2uzcuai	86	6	has	have	VBZ
cord-029813-o2uzcuai	86	7	ranged	range	VBN
cord-029813-o2uzcuai	86	8	widely	widely	RB
cord-029813-o2uzcuai	86	9	from	from	IN
cord-029813-o2uzcuai	86	10	approximately	approximately	RB
cord-029813-o2uzcuai	86	11	5	5	CD
cord-029813-o2uzcuai	86	12	-	-	SYM
cord-029813-o2uzcuai	86	13	60	60	CD
cord-029813-o2uzcuai	86	14	%	%	NN
cord-029813-o2uzcuai	86	15	across	across	IN
cord-029813-o2uzcuai	86	16	various	various	JJ
cord-029813-o2uzcuai	86	17	reports	report	NNS
cord-029813-o2uzcuai	86	18	,	,	,
cord-029813-o2uzcuai	86	19	but	but	CC
cord-029813-o2uzcuai	86	20	some	some	DT
cord-029813-o2uzcuai	86	21	studies	study	NNS
cord-029813-o2uzcuai	86	22	have	have	VBP
cord-029813-o2uzcuai	86	23	not	not	RB
cord-029813-o2uzcuai	86	24	had	have	VBN
cord-029813-o2uzcuai	86	25	sufficient	sufficient	JJ
cord-029813-o2uzcuai	86	26	follow	follow	NN
cord-029813-o2uzcuai	86	27	-	-	HYPH
cord-029813-o2uzcuai	86	28	up	up	NN
cord-029813-o2uzcuai	86	29	to	to	TO
cord-029813-o2uzcuai	86	30	document	document	VB
cord-029813-o2uzcuai	86	31	the	the	DT
cord-029813-o2uzcuai	86	32	development	development	NN
cord-029813-o2uzcuai	86	33	of	of	IN
cord-029813-o2uzcuai	86	34	later	later	JJ
cord-029813-o2uzcuai	86	35	onset	onset	NN
cord-029813-o2uzcuai	86	36	of	of	IN
cord-029813-o2uzcuai	86	37	symptoms	symptom	NNS
cord-029813-o2uzcuai	86	38	.	.	.
cord-029813-o2uzcuai	87	1	The	the	DT
cord-029813-o2uzcuai	87	2	factors	factor	NNS
cord-029813-o2uzcuai	87	3	that	that	WDT
cord-029813-o2uzcuai	87	4	might	may	MD
cord-029813-o2uzcuai	87	5	impact	impact	VB
cord-029813-o2uzcuai	87	6	on	on	IN
cord-029813-o2uzcuai	87	7	likelihood	likelihood	NN
cord-029813-o2uzcuai	87	8	of	of	IN
cord-029813-o2uzcuai	87	9	asymptomatic	asymptomatic	JJ
cord-029813-o2uzcuai	87	10	infection	infection	NN
cord-029813-o2uzcuai	87	11	(	(	-LRB-
cord-029813-o2uzcuai	87	12	e.g.	e.g.	RB
cord-029813-o2uzcuai	87	13	,	,	,
cord-029813-o2uzcuai	87	14	upper	upper	JJ
cord-029813-o2uzcuai	87	15	vs	vs	IN
cord-029813-o2uzcuai	87	16	lower	low	JJR
cord-029813-o2uzcuai	87	17	respiratory	respiratory	JJ
cord-029813-o2uzcuai	87	18	tract	tract	NN
cord-029813-o2uzcuai	87	19	virus	virus	NN
cord-029813-o2uzcuai	87	20	exposure	exposure	NN
cord-029813-o2uzcuai	87	21	,	,	,
cord-029813-o2uzcuai	87	22	infectious	infectious	JJ
cord-029813-o2uzcuai	87	23	virus	virus	NN
cord-029813-o2uzcuai	87	24	inoculum	inoculum	NN
cord-029813-o2uzcuai	87	25	size	size	NN
cord-029813-o2uzcuai	87	26	,	,	,
cord-029813-o2uzcuai	87	27	pre	pre	JJ
cord-029813-o2uzcuai	87	28	-	-	JJ
cord-029813-o2uzcuai	87	29	existing	existing	JJ
cord-029813-o2uzcuai	87	30	,	,	,
cord-029813-o2uzcuai	87	31	cross	cross	JJ
cord-029813-o2uzcuai	87	32	-	-	JJ
cord-029813-o2uzcuai	87	33	reactive	reactive	JJ
cord-029813-o2uzcuai	87	34	immunity	immunity	NN
cord-029813-o2uzcuai	87	35	)	)	-RRB-
cord-029813-o2uzcuai	87	36	have	have	VBP
cord-029813-o2uzcuai	87	37	not	not	RB
cord-029813-o2uzcuai	87	38	been	be	VBN
cord-029813-o2uzcuai	87	39	clarified	clarify	VBN
cord-029813-o2uzcuai	87	40	.	.	.
cord-029813-o2uzcuai	88	1	Of	of	IN
cord-029813-o2uzcuai	88	2	note	note	NN
cord-029813-o2uzcuai	88	3	,	,	,
cord-029813-o2uzcuai	88	4	a	a	DT
cord-029813-o2uzcuai	88	5	large	large	JJ
cord-029813-o2uzcuai	88	6	portion	portion	NN
cord-029813-o2uzcuai	88	7	of	of	IN
cord-029813-o2uzcuai	88	8	pandemic	pandemic	NN
cord-029813-o2uzcuai	88	9	and	and	CC
cord-029813-o2uzcuai	88	10	seasonal	seasonal	JJ
cord-029813-o2uzcuai	88	11	influenza	influenza	NN
cord-029813-o2uzcuai	88	12	infections	infection	NNS
cord-029813-o2uzcuai	88	13	are	be	VBP
cord-029813-o2uzcuai	88	14	asymptomatic	asymptomatic	JJ
cord-029813-o2uzcuai	88	15	or	or	CC
cord-029813-o2uzcuai	88	16	very	very	RB
cord-029813-o2uzcuai	88	17	mild	mild	JJ
cord-029813-o2uzcuai	88	18	and	and	CC
cord-029813-o2uzcuai	88	19	detected	detect	VBN
cord-029813-o2uzcuai	88	20	retrospectively	retrospectively	RB
cord-029813-o2uzcuai	88	21	in	in	IN
cord-029813-o2uzcuai	88	22	serologic	serologic	NNP
cord-029813-o2uzcuai	88	23	studies	study	NNS
cord-029813-o2uzcuai	88	24	.	.	.
cord-029813-o2uzcuai	89	1	The	the	DT
cord-029813-o2uzcuai	89	2	extent	extent	NN
cord-029813-o2uzcuai	89	3	to	to	TO
cord-029813-o2uzcuai	89	4	which	which	WDT
cord-029813-o2uzcuai	89	5	such	such	JJ
cord-029813-o2uzcuai	89	6	persons	person	NNS
cord-029813-o2uzcuai	89	7	contribute	contribute	VBP
cord-029813-o2uzcuai	89	8	to	to	IN
cord-029813-o2uzcuai	89	9	transmission	transmission	NN
cord-029813-o2uzcuai	89	10	remains	remain	VBZ
cord-029813-o2uzcuai	89	11	uncertain	uncertain	JJ
cord-029813-o2uzcuai	89	12	.	.	.
cord-029813-o2uzcuai	90	1	However	however	RB
cord-029813-o2uzcuai	90	2	,	,	,
cord-029813-o2uzcuai	90	3	studies	study	NNS
cord-029813-o2uzcuai	90	4	of	of	IN
cord-029813-o2uzcuai	90	5	COVID-19	covid-19	JJ
cord-029813-o2uzcuai	90	6	clusters	cluster	NNS
cord-029813-o2uzcuai	90	7	have	have	VBP
cord-029813-o2uzcuai	90	8	implicated	implicate	VBN
cord-029813-o2uzcuai	90	9	the	the	DT
cord-029813-o2uzcuai	90	10	importance	importance	NN
cord-029813-o2uzcuai	90	11	of	of	IN
cord-029813-o2uzcuai	90	12	pre	pre	JJ
cord-029813-o2uzcuai	90	13	-	-	JJ
cord-029813-o2uzcuai	90	14	or	or	CC
cord-029813-o2uzcuai	90	15	asymptomatic	asymptomatic	JJ
cord-029813-o2uzcuai	90	16	persons	person	NNS
cord-029813-o2uzcuai	90	17	in	in	IN
cord-029813-o2uzcuai	90	18	transmission	transmission	NN
cord-029813-o2uzcuai	90	19	,	,	,
cord-029813-o2uzcuai	90	20	so	so	IN
cord-029813-o2uzcuai	90	21	that	that	DT
cord-029813-o2uzcuai	90	22	control	control	NN
cord-029813-o2uzcuai	90	23	measures	measure	NNS
cord-029813-o2uzcuai	90	24	clearly	clearly	RB
cord-029813-o2uzcuai	90	25	need	need	VBP
cord-029813-o2uzcuai	90	26	to	to	TO
cord-029813-o2uzcuai	90	27	expand	expand	VB
cord-029813-o2uzcuai	90	28	testing	testing	NN
cord-029813-o2uzcuai	90	29	and	and	CC
cord-029813-o2uzcuai	90	30	isolation	isolation	NN
cord-029813-o2uzcuai	90	31	beyond	beyond	IN
cord-029813-o2uzcuai	90	32	those	those	DT
cord-029813-o2uzcuai	90	33	with	with	IN
cord-029813-o2uzcuai	90	34	symptoms	symptom	NNS
cord-029813-o2uzcuai	90	35	.	.	.
cord-029813-o2uzcuai	91	1	A	a	DT
cord-029813-o2uzcuai	91	2	recent	recent	JJ
cord-029813-o2uzcuai	91	3	modeling	modeling	NN
cord-029813-o2uzcuai	91	4	study	study	NN
cord-029813-o2uzcuai	91	5	estimated	estimate	VBD
cord-029813-o2uzcuai	91	6	that	that	IN
cord-029813-o2uzcuai	91	7	44	44	CD
cord-029813-o2uzcuai	91	8	%	%	NN
cord-029813-o2uzcuai	91	9	(	(	-LRB-
cord-029813-o2uzcuai	91	10	95	95	CD
cord-029813-o2uzcuai	91	11	%	%	NN
cord-029813-o2uzcuai	91	12	CI	ci	NN
cord-029813-o2uzcuai	91	13	:	:	:
cord-029813-o2uzcuai	91	14	25	25	CD
cord-029813-o2uzcuai	91	15	-	-	SYM
cord-029813-o2uzcuai	91	16	69	69	CD
cord-029813-o2uzcuai	91	17	%	%	NN
cord-029813-o2uzcuai	91	18	)	)	-RRB-
cord-029813-o2uzcuai	91	19	of	of	IN
cord-029813-o2uzcuai	91	20	secondary	secondary	JJ
cord-029813-o2uzcuai	91	21	cases	case	NNS
cord-029813-o2uzcuai	91	22	were	be	VBD
cord-029813-o2uzcuai	91	23	infected	infect	VBN
cord-029813-o2uzcuai	91	24	during	during	IN
cord-029813-o2uzcuai	91	25	the	the	DT
cord-029813-o2uzcuai	91	26	presymptomatic	presymptomatic	JJ
cord-029813-o2uzcuai	91	27	stage	stage	NN
cord-029813-o2uzcuai	91	28	of	of	IN
cord-029813-o2uzcuai	91	29	index	index	NN
cord-029813-o2uzcuai	91	30	cases	case	NNS
cord-029813-o2uzcuai	91	31	[	[	-LRB-
cord-029813-o2uzcuai	91	32	12	12	CD
cord-029813-o2uzcuai	91	33	]	]	-RRB-
cord-029813-o2uzcuai	91	34	.	.	.
cord-029813-o2uzcuai	92	1	Such	such	JJ
cord-029813-o2uzcuai	92	2	findings	finding	NNS
cord-029813-o2uzcuai	92	3	,	,	,
cord-029813-o2uzcuai	92	4	again	again	RB
cord-029813-o2uzcuai	92	5	,	,	,
cord-029813-o2uzcuai	92	6	highlight	highlight	VB
cord-029813-o2uzcuai	92	7	the	the	DT
cord-029813-o2uzcuai	92	8	importance	importance	NN
cord-029813-o2uzcuai	92	9	of	of	IN
cord-029813-o2uzcuai	92	10	wide	wide	JJ
cord-029813-o2uzcuai	92	11	-	-	HYPH
cord-029813-o2uzcuai	92	12	scale	scale	NN
cord-029813-o2uzcuai	92	13	,	,	,
cord-029813-o2uzcuai	92	14	rapid	rapid	JJ
cord-029813-o2uzcuai	92	15	detection	detection	NN
cord-029813-o2uzcuai	92	16	of	of	IN
cord-029813-o2uzcuai	92	17	SARS	SARS	NNP
cord-029813-o2uzcuai	92	18	-	-	HYPH
cord-029813-o2uzcuai	92	19	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	92	20	infections	infection	NNS
cord-029813-o2uzcuai	92	21	for	for	IN
cord-029813-o2uzcuai	92	22	effective	effective	JJ
cord-029813-o2uzcuai	92	23	application	application	NN
cord-029813-o2uzcuai	92	24	of	of	IN
cord-029813-o2uzcuai	92	25	traditional	traditional	JJ
cord-029813-o2uzcuai	92	26	nonpharmaceutical	nonpharmaceutical	JJ
cord-029813-o2uzcuai	92	27	control	control	NN
cord-029813-o2uzcuai	92	28	measures	measure	NNS
cord-029813-o2uzcuai	92	29	(	(	-LRB-
cord-029813-o2uzcuai	92	30	e.g.	e.g.	RB
cord-029813-o2uzcuai	92	31	,	,	,
cord-029813-o2uzcuai	92	32	masking	mask	VBG
cord-029813-o2uzcuai	92	33	,	,	,
cord-029813-o2uzcuai	92	34	social	social	JJ
cord-029813-o2uzcuai	92	35	distancing	distancing	NN
cord-029813-o2uzcuai	92	36	,	,	,
cord-029813-o2uzcuai	92	37	quarantine	quarantine	NN
cord-029813-o2uzcuai	92	38	of	of	IN
cord-029813-o2uzcuai	92	39	those	those	DT
cord-029813-o2uzcuai	92	40	possibly	possibly	RB
cord-029813-o2uzcuai	92	41	exposed	expose	VBN
cord-029813-o2uzcuai	92	42	)	)	-RRB-
cord-029813-o2uzcuai	92	43	.	.	.
cord-029813-o2uzcuai	93	1	Following	follow	VBG
cord-029813-o2uzcuai	93	2	a	a	DT
cord-029813-o2uzcuai	93	3	broad	broad	RB
cord-029813-o2uzcuai	93	4	-	-	HYPH
cord-029813-o2uzcuai	93	5	ranging	range	VBG
cord-029813-o2uzcuai	93	6	introduction	introduction	NN
cord-029813-o2uzcuai	93	7	,	,	,
cord-029813-o2uzcuai	93	8	Nemunaitis	Nemunaitis	NNP
cord-029813-o2uzcuai	93	9	et	et	NNP
cord-029813-o2uzcuai	93	10	al	al	NNP
cord-029813-o2uzcuai	93	11	.	.	.
cord-029813-o2uzcuai	94	1	focus	focus	VB
cord-029813-o2uzcuai	94	2	on	on	IN
cord-029813-o2uzcuai	94	3	the	the	DT
cord-029813-o2uzcuai	94	4	strategy	strategy	NN
cord-029813-o2uzcuai	94	5	of	of	IN
cord-029813-o2uzcuai	94	6	repurposing	repurpose	VBG
cord-029813-o2uzcuai	94	7	a	a	DT
cord-029813-o2uzcuai	94	8	personalized	personalized	JJ
cord-029813-o2uzcuai	94	9	cancer	cancer	NN
cord-029813-o2uzcuai	94	10	treatment	treatment	NN
cord-029813-o2uzcuai	94	11	with	with	IN
cord-029813-o2uzcuai	94	12	the	the	DT
cord-029813-o2uzcuai	94	13	proprietary	proprietary	JJ
cord-029813-o2uzcuai	94	14	name	name	NN
cord-029813-o2uzcuai	94	15	Vigil	Vigil	NNP
cord-029813-o2uzcuai	94	16	R	R	NNP
cord-029813-o2uzcuai	94	17	currently	currently	RB
cord-029813-o2uzcuai	94	18	in	in	IN
cord-029813-o2uzcuai	94	19	Phase	Phase	NNP
cord-029813-o2uzcuai	94	20	III	iii	CD
cord-029813-o2uzcuai	94	21	trials	trial	NNS
cord-029813-o2uzcuai	94	22	to	to	TO
cord-029813-o2uzcuai	94	23	treat	treat	VB
cord-029813-o2uzcuai	94	24	SARS	SARS	NNP
cord-029813-o2uzcuai	94	25	-	-	HYPH
cord-029813-o2uzcuai	94	26	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	94	27	infections	infection	NNS
cord-029813-o2uzcuai	94	28	[	[	-LRB-
cord-029813-o2uzcuai	94	29	13	13	CD
cord-029813-o2uzcuai	94	30	]	]	-RRB-
cord-029813-o2uzcuai	94	31	.	.	.
cord-029813-o2uzcuai	95	1	The	the	DT
cord-029813-o2uzcuai	95	2	cancer	cancer	NN
cord-029813-o2uzcuai	95	3	therapy	therapy	NN
cord-029813-o2uzcuai	95	4	involves	involve	VBZ
cord-029813-o2uzcuai	95	5	harvesting	harvest	VBG
cord-029813-o2uzcuai	95	6	tumor	tumor	NN
cord-029813-o2uzcuai	95	7	cells	cell	NNS
cord-029813-o2uzcuai	95	8	from	from	IN
cord-029813-o2uzcuai	95	9	a	a	DT
cord-029813-o2uzcuai	95	10	patient	patient	NN
cord-029813-o2uzcuai	95	11	,	,	,
cord-029813-o2uzcuai	95	12	transfecting	transfecte	VBG
cord-029813-o2uzcuai	95	13	with	with	IN
cord-029813-o2uzcuai	95	14	a	a	DT
cord-029813-o2uzcuai	95	15	dual	dual	JJ
cord-029813-o2uzcuai	95	16	shRNA	shrna	NN
cord-029813-o2uzcuai	95	17	construct	construct	NN
cord-029813-o2uzcuai	95	18	that	that	WDT
cord-029813-o2uzcuai	95	19	both	both	DT
cord-029813-o2uzcuai	95	20	inhibit	inhibit	VB
cord-029813-o2uzcuai	95	21	furin	furin	NN
cord-029813-o2uzcuai	95	22	production	production	NN
cord-029813-o2uzcuai	95	23	and	and	CC
cord-029813-o2uzcuai	95	24	stimulate	stimulate	VB
cord-029813-o2uzcuai	95	25	GM	GM	NNP
cord-029813-o2uzcuai	95	26	-	-	HYPH
cord-029813-o2uzcuai	95	27	CSF	csf	NN
cord-029813-o2uzcuai	95	28	expression	expression	NN
cord-029813-o2uzcuai	95	29	to	to	TO
cord-029813-o2uzcuai	95	30	enhance	enhance	VB
cord-029813-o2uzcuai	95	31	immunogenicity	immunogenicity	NN
cord-029813-o2uzcuai	95	32	of	of	IN
cord-029813-o2uzcuai	95	33	the	the	DT
cord-029813-o2uzcuai	95	34	tumor	tumor	NN
cord-029813-o2uzcuai	95	35	cells	cell	NNS
cord-029813-o2uzcuai	95	36	,	,	,
cord-029813-o2uzcuai	95	37	and	and	CC
cord-029813-o2uzcuai	95	38	reintroducing	reintroduce	VBG
cord-029813-o2uzcuai	95	39	them	-PRON-	PRP
cord-029813-o2uzcuai	95	40	into	into	IN
cord-029813-o2uzcuai	95	41	the	the	DT
cord-029813-o2uzcuai	95	42	patient	patient	NN
cord-029813-o2uzcuai	95	43	.	.	.
cord-029813-o2uzcuai	96	1	The	the	DT
cord-029813-o2uzcuai	96	2	authors	author	NNS
cord-029813-o2uzcuai	96	3	point	point	VBP
cord-029813-o2uzcuai	96	4	out	out	RP
cord-029813-o2uzcuai	96	5	that	that	IN
cord-029813-o2uzcuai	96	6	the	the	DT
cord-029813-o2uzcuai	96	7	dual	dual	JJ
cord-029813-o2uzcuai	96	8	actions	action	NNS
cord-029813-o2uzcuai	96	9	of	of	IN
cord-029813-o2uzcuai	96	10	their	-PRON-	PRP$
cord-029813-o2uzcuai	96	11	plasmid	plasmid	NN
cord-029813-o2uzcuai	96	12	could	could	MD
cord-029813-o2uzcuai	96	13	result	result	VB
cord-029813-o2uzcuai	96	14	in	in	IN
cord-029813-o2uzcuai	96	15	both	both	DT
cord-029813-o2uzcuai	96	16	antiviral	antiviral	JJ
cord-029813-o2uzcuai	96	17	and	and	CC
cord-029813-o2uzcuai	96	18	anti	anti	JJ
cord-029813-o2uzcuai	96	19	-	-	JJ
cord-029813-o2uzcuai	96	20	inflammatory	inflammatory	JJ
cord-029813-o2uzcuai	96	21	effects	effect	NNS
cord-029813-o2uzcuai	96	22	in	in	IN
cord-029813-o2uzcuai	96	23	COVID-19	COVID-19	NNP
cord-029813-o2uzcuai	96	24	.	.	.
cord-029813-o2uzcuai	97	1	However	however	RB
cord-029813-o2uzcuai	97	2	,	,	,
cord-029813-o2uzcuai	97	3	the	the	DT
cord-029813-o2uzcuai	97	4	cancer	cancer	NN
cord-029813-o2uzcuai	97	5	treatment	treatment	NN
cord-029813-o2uzcuai	97	6	strategy	strategy	NN
cord-029813-o2uzcuai	97	7	is	be	VBZ
cord-029813-o2uzcuai	97	8	a	a	DT
cord-029813-o2uzcuai	97	9	very	very	RB
cord-029813-o2uzcuai	97	10	different	different	JJ
cord-029813-o2uzcuai	97	11	proposition	proposition	NN
cord-029813-o2uzcuai	97	12	from	from	IN
cord-029813-o2uzcuai	97	13	in	in	IN
cord-029813-o2uzcuai	97	14	vivo	vivo	NN
cord-029813-o2uzcuai	97	15	transfection	transfection	NN
cord-029813-o2uzcuai	97	16	of	of	IN
cord-029813-o2uzcuai	97	17	lung	lung	NN
cord-029813-o2uzcuai	97	18	epithelial	epithelial	JJ
cord-029813-o2uzcuai	97	19	cells	cell	NNS
cord-029813-o2uzcuai	97	20	by	by	IN
cord-029813-o2uzcuai	97	21	their	-PRON-	PRP$
cord-029813-o2uzcuai	97	22	proposed	propose	VBN
cord-029813-o2uzcuai	97	23	inhalation	inhalation	NN
cord-029813-o2uzcuai	97	24	delivery	delivery	NN
cord-029813-o2uzcuai	97	25	of	of	IN
cord-029813-o2uzcuai	97	26	the	the	DT
cord-029813-o2uzcuai	97	27	plasmid	plasmid	NN
cord-029813-o2uzcuai	97	28	.	.	.
cord-029813-o2uzcuai	98	1	Effective	effective	JJ
cord-029813-o2uzcuai	98	2	and	and	CC
cord-029813-o2uzcuai	98	3	safe	safe	JJ
cord-029813-o2uzcuai	98	4	aerosol	aerosol	NN
cord-029813-o2uzcuai	98	5	delivery	delivery	NN
cord-029813-o2uzcuai	98	6	of	of	IN
cord-029813-o2uzcuai	98	7	small	small	JJ
cord-029813-o2uzcuai	98	8	-	-	HYPH
cord-029813-o2uzcuai	98	9	molecular	molecular	JJ
cord-029813-o2uzcuai	98	10	weight	weight	NN
cord-029813-o2uzcuai	99	1	antivirals	antiviral	NNS
cord-029813-o2uzcuai	99	2	has	have	VBZ
cord-029813-o2uzcuai	99	3	proven	prove	VBN
cord-029813-o2uzcuai	99	4	very	very	RB
cord-029813-o2uzcuai	99	5	challenging	challenging	JJ
cord-029813-o2uzcuai	99	6	in	in	IN
cord-029813-o2uzcuai	99	7	viral	viral	JJ
cord-029813-o2uzcuai	99	8	pneumonias	pneumonia	NNS
cord-029813-o2uzcuai	99	9	to	to	IN
cord-029813-o2uzcuai	99	10	date	date	NN
cord-029813-o2uzcuai	99	11	,	,	,
cord-029813-o2uzcuai	99	12	and	and	CC
cord-029813-o2uzcuai	99	13	the	the	DT
cord-029813-o2uzcuai	99	14	fragile	fragile	JJ
cord-029813-o2uzcuai	99	15	nature	nature	NN
cord-029813-o2uzcuai	99	16	of	of	IN
cord-029813-o2uzcuai	99	17	DNA	dna	NN
cord-029813-o2uzcuai	99	18	plasmids	plasmid	NNS
cord-029813-o2uzcuai	99	19	adds	add	VBZ
cord-029813-o2uzcuai	99	20	complexity	complexity	NN
cord-029813-o2uzcuai	99	21	to	to	IN
cord-029813-o2uzcuai	99	22	the	the	DT
cord-029813-o2uzcuai	99	23	process	process	NN
cord-029813-o2uzcuai	99	24	.	.	.
cord-029813-o2uzcuai	100	1	Depending	depend	VBG
cord-029813-o2uzcuai	100	2	on	on	IN
cord-029813-o2uzcuai	100	3	timing	timing	NN
cord-029813-o2uzcuai	100	4	,	,	,
cord-029813-o2uzcuai	100	5	there	there	EX
cord-029813-o2uzcuai	100	6	is	be	VBZ
cord-029813-o2uzcuai	100	7	also	also	RB
cord-029813-o2uzcuai	100	8	the	the	DT
cord-029813-o2uzcuai	100	9	concern	concern	NN
cord-029813-o2uzcuai	100	10	that	that	IN
cord-029813-o2uzcuai	100	11	nonspecific	nonspecific	JJ
cord-029813-o2uzcuai	100	12	GM	GM	NNP
cord-029813-o2uzcuai	100	13	-	-	HYPH
cord-029813-o2uzcuai	100	14	CSF	csf	NN
cord-029813-o2uzcuai	100	15	stimulation	stimulation	NN
cord-029813-o2uzcuai	100	16	in	in	IN
cord-029813-o2uzcuai	100	17	lung	lung	NN
cord-029813-o2uzcuai	100	18	might	may	MD
cord-029813-o2uzcuai	100	19	exacerbate	exacerbate	VB
cord-029813-o2uzcuai	100	20	ARDS	ARDS	NNP
cord-029813-o2uzcuai	100	21	.	.	.
cord-029813-o2uzcuai	101	1	Indeed	indeed	RB
cord-029813-o2uzcuai	101	2	,	,	,
cord-029813-o2uzcuai	101	3	there	there	EX
cord-029813-o2uzcuai	101	4	is	be	VBZ
cord-029813-o2uzcuai	101	5	great	great	JJ
cord-029813-o2uzcuai	101	6	interest	interest	NN
cord-029813-o2uzcuai	101	7	in	in	IN
cord-029813-o2uzcuai	101	8	the	the	DT
cord-029813-o2uzcuai	101	9	use	use	NN
cord-029813-o2uzcuai	101	10	of	of	IN
cord-029813-o2uzcuai	101	11	immunomodulators	immunomodulator	NNS
cord-029813-o2uzcuai	101	12	in	in	IN
cord-029813-o2uzcuai	101	13	the	the	DT
cord-029813-o2uzcuai	101	14	subgroup	subgroup	NN
cord-029813-o2uzcuai	101	15	of	of	IN
cord-029813-o2uzcuai	101	16	COVID-19	covid-19	JJ
cord-029813-o2uzcuai	101	17	patients	patient	NNS
cord-029813-o2uzcuai	101	18	who	who	WP
cord-029813-o2uzcuai	101	19	develop	develop	VBP
cord-029813-o2uzcuai	101	20	a	a	DT
cord-029813-o2uzcuai	101	21	hyperinflammatory	hyperinflammatory	JJ
cord-029813-o2uzcuai	101	22	state	state	NN
cord-029813-o2uzcuai	101	23	associated	associate	VBN
cord-029813-o2uzcuai	101	24	with	with	IN
cord-029813-o2uzcuai	101	25	lung	lung	NN
cord-029813-o2uzcuai	101	26	injury	injury	NN
cord-029813-o2uzcuai	101	27	and	and	CC
cord-029813-o2uzcuai	101	28	often	often	RB
cord-029813-o2uzcuai	101	29	other	other	JJ
cord-029813-o2uzcuai	101	30	organ	organ	NN
cord-029813-o2uzcuai	101	31	failure	failure	NN
cord-029813-o2uzcuai	101	32	.	.	.
cord-029813-o2uzcuai	102	1	A	a	DT
cord-029813-o2uzcuai	102	2	large	large	JJ
cord-029813-o2uzcuai	102	3	number	number	NN
cord-029813-o2uzcuai	102	4	of	of	IN
cord-029813-o2uzcuai	102	5	clinical	clinical	JJ
cord-029813-o2uzcuai	102	6	studies	study	NNS
cord-029813-o2uzcuai	102	7	targeting	target	VBG
cord-029813-o2uzcuai	102	8	excessively	excessively	RB
cord-029813-o2uzcuai	102	9	proinflammatory	proinflammatory	JJ
cord-029813-o2uzcuai	102	10	immune	immune	JJ
cord-029813-o2uzcuai	102	11	responses	response	NNS
cord-029813-o2uzcuai	102	12	are	be	VBP
cord-029813-o2uzcuai	102	13	currently	currently	RB
cord-029813-o2uzcuai	102	14	in	in	IN
cord-029813-o2uzcuai	102	15	progress	progress	NN
cord-029813-o2uzcuai	102	16	in	in	IN
cord-029813-o2uzcuai	102	17	COVID-19	COVID-19	NNP
cord-029813-o2uzcuai	102	18	.	.	.
cord-029813-o2uzcuai	103	1	One	one	CD
cord-029813-o2uzcuai	103	2	agent	agent	NN
cord-029813-o2uzcuai	103	3	of	of	IN
cord-029813-o2uzcuai	103	4	particular	particular	JJ
cord-029813-o2uzcuai	103	5	interest	interest	NN
cord-029813-o2uzcuai	103	6	is	be	VBZ
cord-029813-o2uzcuai	103	7	baricitinib	baricitinib	NNP
cord-029813-o2uzcuai	103	8	,	,	,
cord-029813-o2uzcuai	103	9	an	an	DT
cord-029813-o2uzcuai	103	10	oral	oral	JJ
cord-029813-o2uzcuai	103	11	inhibitor	inhibitor	NN
cord-029813-o2uzcuai	103	12	of	of	IN
cord-029813-o2uzcuai	103	13	JAK1	JAK1	NNP
cord-029813-o2uzcuai	103	14	and	and	CC
cord-029813-o2uzcuai	103	15	JAK2	JAK2	NNP
cord-029813-o2uzcuai	103	16	and	and	CC
cord-029813-o2uzcuai	103	17	NAK	NAK	NNP
cord-029813-o2uzcuai	103	18	family	family	NN
cord-029813-o2uzcuai	103	19	members	member	NNS
cord-029813-o2uzcuai	103	20	that	that	WDT
cord-029813-o2uzcuai	103	21	is	be	VBZ
cord-029813-o2uzcuai	103	22	approved	approve	VBN
cord-029813-o2uzcuai	103	23	for	for	IN
cord-029813-o2uzcuai	103	24	the	the	DT
cord-029813-o2uzcuai	103	25	treatment	treatment	NN
cord-029813-o2uzcuai	103	26	of	of	IN
cord-029813-o2uzcuai	103	27	rheumatoid	rheumatoid	JJ
cord-029813-o2uzcuai	103	28	arthritis	arthritis	NN
cord-029813-o2uzcuai	103	29	in	in	IN
cord-029813-o2uzcuai	103	30	adults	adult	NNS
cord-029813-o2uzcuai	103	31	.	.	.
cord-029813-o2uzcuai	104	1	It	-PRON-	PRP
cord-029813-o2uzcuai	104	2	has	have	VBZ
cord-029813-o2uzcuai	104	3	been	be	VBN
cord-029813-o2uzcuai	104	4	proposed	propose	VBN
cord-029813-o2uzcuai	104	5	as	as	IN
cord-029813-o2uzcuai	104	6	a	a	DT
cord-029813-o2uzcuai	104	7	therapeutic	therapeutic	JJ
cord-029813-o2uzcuai	104	8	option	option	NN
cord-029813-o2uzcuai	104	9	for	for	IN
cord-029813-o2uzcuai	104	10	COVID-19	covid-19	NN
cord-029813-o2uzcuai	104	11	because	because	IN
cord-029813-o2uzcuai	104	12	of	of	IN
cord-029813-o2uzcuai	104	13	its	-PRON-	PRP$
cord-029813-o2uzcuai	104	14	anti	anti	JJ
cord-029813-o2uzcuai	104	15	-	-	JJ
cord-029813-o2uzcuai	104	16	inflammatory	inflammatory	JJ
cord-029813-o2uzcuai	104	17	and	and	CC
cord-029813-o2uzcuai	104	18	anticoronaviral	anticoronaviral	NN
cord-029813-o2uzcuai	104	19	properties	property	NNS
cord-029813-o2uzcuai	104	20	in	in	IN
cord-029813-o2uzcuai	104	21	preclinical	preclinical	JJ
cord-029813-o2uzcuai	104	22	and	and	CC
cord-029813-o2uzcuai	104	23	limited	limited	JJ
cord-029813-o2uzcuai	104	24	clinical	clinical	JJ
cord-029813-o2uzcuai	104	25	studies	study	NNS
cord-029813-o2uzcuai	104	26	[	[	-LRB-
cord-029813-o2uzcuai	104	27	14	14	CD
cord-029813-o2uzcuai	104	28	]	]	-RRB-
cord-029813-o2uzcuai	104	29	.	.	.
cord-029813-o2uzcuai	105	1	future	future	JJ
cord-029813-o2uzcuai	105	2	science	science	NN
cord-029813-o2uzcuai	105	3	group	group	NN
cord-029813-o2uzcuai	105	4	10	10	CD
cord-029813-o2uzcuai	105	5	.2217	.2217	.
cord-029813-o2uzcuai	106	1	/	/	NFP
cord-029813-o2uzcuai	107	1	fvl-2020	fvl-2020	NN
cord-029813-o2uzcuai	107	2	-	-	HYPH
cord-029813-o2uzcuai	107	3	0211	0211	CD
cord-029813-o2uzcuai	108	1	An	an	DT
cord-029813-o2uzcuai	108	2	obvious	obvious	JJ
cord-029813-o2uzcuai	108	3	strategy	strategy	NN
cord-029813-o2uzcuai	108	4	is	be	VBZ
cord-029813-o2uzcuai	108	5	to	to	TO
cord-029813-o2uzcuai	108	6	combine	combine	VB
cord-029813-o2uzcuai	108	7	antivirals	antiviral	NNS
cord-029813-o2uzcuai	108	8	with	with	IN
cord-029813-o2uzcuai	108	9	immunomodulators	immunomodulator	NNS
cord-029813-o2uzcuai	108	10	in	in	IN
cord-029813-o2uzcuai	108	11	severe	severe	JJ
cord-029813-o2uzcuai	108	12	COVID-19	covid-19	NN
cord-029813-o2uzcuai	108	13	,	,	,
cord-029813-o2uzcuai	108	14	and	and	CC
cord-029813-o2uzcuai	108	15	a	a	DT
cord-029813-o2uzcuai	108	16	randomized	randomized	JJ
cord-029813-o2uzcuai	108	17	,	,	,
cord-029813-o2uzcuai	108	18	placebo	placebo	NN
cord-029813-o2uzcuai	108	19	-	-	HYPH
cord-029813-o2uzcuai	108	20	controlled	control	VBN
cord-029813-o2uzcuai	108	21	trial	trial	NN
cord-029813-o2uzcuai	108	22	of	of	IN
cord-029813-o2uzcuai	108	23	baricitinib	baricitinib	NNP
cord-029813-o2uzcuai	108	24	's	's	POS
cord-029813-o2uzcuai	108	25	efficacy	efficacy	NN
cord-029813-o2uzcuai	108	26	in	in	IN
cord-029813-o2uzcuai	108	27	combination	combination	NN
cord-029813-o2uzcuai	108	28	with	with	IN
cord-029813-o2uzcuai	108	29	remdesivir	remdesivir	NNP
cord-029813-o2uzcuai	108	30	is	be	VBZ
cord-029813-o2uzcuai	108	31	ongoing	ongoing	JJ
cord-029813-o2uzcuai	108	32	at	at	IN
cord-029813-o2uzcuai	108	33	present	present	NN
cord-029813-o2uzcuai	108	34	.	.	.
cord-029813-o2uzcuai	109	1	In	in	IN
cord-029813-o2uzcuai	109	2	summary	summary	NN
cord-029813-o2uzcuai	109	3	,	,	,
cord-029813-o2uzcuai	109	4	this	this	DT
cord-029813-o2uzcuai	109	5	special	special	JJ
cord-029813-o2uzcuai	109	6	issue	issue	NN
cord-029813-o2uzcuai	109	7	addresses	address	VBZ
cord-029813-o2uzcuai	109	8	many	many	JJ
cord-029813-o2uzcuai	109	9	different	different	JJ
cord-029813-o2uzcuai	109	10	aspects	aspect	NNS
cord-029813-o2uzcuai	109	11	of	of	IN
cord-029813-o2uzcuai	109	12	the	the	DT
cord-029813-o2uzcuai	109	13	ongoing	ongoing	JJ
cord-029813-o2uzcuai	109	14	pandemic	pandemic	NN
cord-029813-o2uzcuai	109	15	.	.	.
cord-029813-o2uzcuai	110	1	Given	give	VBN
cord-029813-o2uzcuai	110	2	the	the	DT
cord-029813-o2uzcuai	110	3	numerous	numerous	JJ
cord-029813-o2uzcuai	110	4	unanswered	unanswered	JJ
cord-029813-o2uzcuai	110	5	questions	question	NNS
cord-029813-o2uzcuai	110	6	regarding	regard	VBG
cord-029813-o2uzcuai	110	7	SARS	SARS	NNP
cord-029813-o2uzcuai	110	8	-	-	HYPH
cord-029813-o2uzcuai	110	9	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	110	10	and	and	CC
cord-029813-o2uzcuai	110	11	COVID-19	COVID-19	NNP
cord-029813-o2uzcuai	110	12	,	,	,
cord-029813-o2uzcuai	110	13	we	-PRON-	PRP
cord-029813-o2uzcuai	110	14	trust	trust	VBP
cord-029813-o2uzcuai	110	15	that	that	IN
cord-029813-o2uzcuai	110	16	this	this	DT
cord-029813-o2uzcuai	110	17	collection	collection	NN
cord-029813-o2uzcuai	110	18	of	of	IN
cord-029813-o2uzcuai	110	19	articles	article	NNS
cord-029813-o2uzcuai	110	20	will	will	MD
cord-029813-o2uzcuai	110	21	stimulate	stimulate	VB
cord-029813-o2uzcuai	110	22	both	both	DT
cord-029813-o2uzcuai	110	23	discussion	discussion	NN
cord-029813-o2uzcuai	110	24	and	and	CC
cord-029813-o2uzcuai	110	25	further	further	JJ
cord-029813-o2uzcuai	110	26	investigation	investigation	NN
cord-029813-o2uzcuai	110	27	.	.	.
cord-029813-o2uzcuai	111	1	We	-PRON-	PRP
cord-029813-o2uzcuai	111	2	thank	thank	VBP
cord-029813-o2uzcuai	111	3	the	the	DT
cord-029813-o2uzcuai	111	4	authors	author	NNS
cord-029813-o2uzcuai	111	5	,	,	,
cord-029813-o2uzcuai	111	6	reviewers	reviewer	NNS
cord-029813-o2uzcuai	111	7	and	and	CC
cord-029813-o2uzcuai	111	8	the	the	DT
cord-029813-o2uzcuai	111	9	staff	staff	NN
cord-029813-o2uzcuai	111	10	at	at	IN
cord-029813-o2uzcuai	111	11	Future	Future	NNP
cord-029813-o2uzcuai	111	12	Virology	Virology	NNP
cord-029813-o2uzcuai	111	13	for	for	IN
cord-029813-o2uzcuai	111	14	making	make	VBG
cord-029813-o2uzcuai	111	15	this	this	DT
cord-029813-o2uzcuai	111	16	special	special	JJ
cord-029813-o2uzcuai	111	17	issue	issue	NN
cord-029813-o2uzcuai	111	18	possible	possible	JJ
cord-029813-o2uzcuai	111	19	.	.	.
cord-029813-o2uzcuai	112	1	Financial	Financial	NNP
cord-029813-o2uzcuai	112	2	&	&	CC
cord-029813-o2uzcuai	112	3	competing	compete	VBG
cord-029813-o2uzcuai	112	4	interests	interest	NNS
cord-029813-o2uzcuai	112	5	disclosure	disclosure	NN
cord-029813-o2uzcuai	112	6	S	S	NNP
cord-029813-o2uzcuai	112	7	Rusconi	Rusconi	NNP
cord-029813-o2uzcuai	112	8	received	receive	VBD
cord-029813-o2uzcuai	112	9	research	research	NN
cord-029813-o2uzcuai	112	10	grants	grant	NNS
cord-029813-o2uzcuai	112	11	to	to	IN
cord-029813-o2uzcuai	112	12	his	-PRON-	PRP$
cord-029813-o2uzcuai	112	13	Institution	Institution	NNP
cord-029813-o2uzcuai	112	14	from	from	IN
cord-029813-o2uzcuai	112	15	ViiV	ViiV	NNP
cord-029813-o2uzcuai	112	16	Healthcare	Healthcare	NNP
cord-029813-o2uzcuai	112	17	,	,	,
cord-029813-o2uzcuai	112	18	Gilead	Gilead	NNP
cord-029813-o2uzcuai	112	19	Sciences	Sciences	NNPS
cord-029813-o2uzcuai	112	20	and	and	CC
cord-029813-o2uzcuai	112	21	Janssen	Janssen	NNP
cord-029813-o2uzcuai	112	22	,	,	,
cord-029813-o2uzcuai	112	23	outside	outside	IN
cord-029813-o2uzcuai	112	24	the	the	DT
cord-029813-o2uzcuai	112	25	submitted	submit	VBN
cord-029813-o2uzcuai	112	26	work	work	NN
cord-029813-o2uzcuai	112	27	;	;	:
cord-029813-o2uzcuai	112	28	he	-PRON-	PRP
cord-029813-o2uzcuai	112	29	was	be	VBD
cord-029813-o2uzcuai	112	30	also	also	RB
cord-029813-o2uzcuai	112	31	a	a	DT
cord-029813-o2uzcuai	112	32	paid	pay	VBN
cord-029813-o2uzcuai	112	33	consultant	consultant	NN
cord-029813-o2uzcuai	112	34	for	for	IN
cord-029813-o2uzcuai	112	35	ViiV	ViiV	NNP
cord-029813-o2uzcuai	112	36	Healthcare	Healthcare	NNP
cord-029813-o2uzcuai	112	37	,	,	,
cord-029813-o2uzcuai	112	38	Gilead	Gilead	NNP
cord-029813-o2uzcuai	112	39	Sciences	Sciences	NNPS
cord-029813-o2uzcuai	112	40	,	,	,
cord-029813-o2uzcuai	112	41	Merck	Merck	NNP
cord-029813-o2uzcuai	112	42	Sharp	Sharp	NNP
cord-029813-o2uzcuai	112	43	and	and	CC
cord-029813-o2uzcuai	112	44	Dohme	Dohme	NNP
cord-029813-o2uzcuai	112	45	,	,	,
cord-029813-o2uzcuai	112	46	Bristol	Bristol	NNP
cord-029813-o2uzcuai	112	47	-	-	HYPH
cord-029813-o2uzcuai	112	48	Myers	Myers	NNP
cord-029813-o2uzcuai	112	49	Squibb	Squibb	NNP
cord-029813-o2uzcuai	112	50	,	,	,
cord-029813-o2uzcuai	112	51	Janssen	Janssen	NNP
cord-029813-o2uzcuai	112	52	and	and	CC
cord-029813-o2uzcuai	112	53	Mylan	Mylan	NNP
cord-029813-o2uzcuai	112	54	.	.	.
cord-029813-o2uzcuai	113	1	FG	FG	NNP
cord-029813-o2uzcuai	113	2	Hayden	Hayden	NNP
cord-029813-o2uzcuai	113	3	reports	report	VBZ
cord-029813-o2uzcuai	113	4	personal	personal	JJ
cord-029813-o2uzcuai	113	5	fees	fee	NNS
cord-029813-o2uzcuai	113	6	from	from	IN
cord-029813-o2uzcuai	113	7	University	University	NNP
cord-029813-o2uzcuai	113	8	of	of	IN
cord-029813-o2uzcuai	113	9	Alabama	Alabama	NNP
cord-029813-o2uzcuai	113	10	Antiviral	Antiviral	NNP
cord-029813-o2uzcuai	113	11	Drug	Drug	NNP
cord-029813-o2uzcuai	113	12	Discovery	Discovery	NNP
cord-029813-o2uzcuai	113	13	and	and	CC
cord-029813-o2uzcuai	113	14	Development	Development	NNP
cord-029813-o2uzcuai	113	15	Consortium	Consortium	NNP
cord-029813-o2uzcuai	113	16	,	,	,
cord-029813-o2uzcuai	113	17	outside	outside	IN
cord-029813-o2uzcuai	113	18	the	the	DT
cord-029813-o2uzcuai	113	19	submitted	submit	VBN
cord-029813-o2uzcuai	113	20	work	work	NN
cord-029813-o2uzcuai	113	21	;	;	:
cord-029813-o2uzcuai	113	22	and	and	CC
cord-029813-o2uzcuai	113	23	being	be	VBG
cord-029813-o2uzcuai	113	24	a	a	DT
cord-029813-o2uzcuai	113	25	noncompensated	noncompensated	JJ
cord-029813-o2uzcuai	113	26	consultant	consultant	NN
cord-029813-o2uzcuai	113	27	to	to	IN
cord-029813-o2uzcuai	113	28	companies	company	NNS
cord-029813-o2uzcuai	113	29	developing	develop	VBG
cord-029813-o2uzcuai	113	30	therapeutics	therapeutic	NNS
cord-029813-o2uzcuai	113	31	and	and	CC
cord-029813-o2uzcuai	113	32	vaccines	vaccine	NNS
cord-029813-o2uzcuai	113	33	for	for	IN
cord-029813-o2uzcuai	113	34	novel	novel	JJ
cord-029813-o2uzcuai	113	35	coronavirus	coronavirus	NN
cord-029813-o2uzcuai	113	36	infections	infection	NNS
cord-029813-o2uzcuai	113	37	,	,	,
cord-029813-o2uzcuai	113	38	including	include	VBG
cord-029813-o2uzcuai	113	39	Arcturus	Arcturus	NNP
cord-029813-o2uzcuai	113	40	,	,	,
cord-029813-o2uzcuai	113	41	Cidara	Cidara	NNP
cord-029813-o2uzcuai	113	42	,	,	,
cord-029813-o2uzcuai	113	43	FujiFilm	FujiFilm	NNP
cord-029813-o2uzcuai	113	44	,	,	,
cord-029813-o2uzcuai	113	45	Gilead	Gilead	NNP
cord-029813-o2uzcuai	113	46	Sciences	Sciences	NNPS
cord-029813-o2uzcuai	113	47	,	,	,
cord-029813-o2uzcuai	113	48	GlaxoSmithKline	GlaxoSmithKline	NNP
cord-029813-o2uzcuai	113	49	,	,	,
cord-029813-o2uzcuai	113	50	Regeneron	Regeneron	NNP
cord-029813-o2uzcuai	113	51	,	,	,
cord-029813-o2uzcuai	113	52	resTORbio	resTORbio	NNP
cord-029813-o2uzcuai	113	53	,	,	,
cord-029813-o2uzcuai	113	54	Ridgeback	Ridgeback	NNP
cord-029813-o2uzcuai	113	55	Biotherapeutics	Biotherapeutics	NNPS
cord-029813-o2uzcuai	113	56	,	,	,
cord-029813-o2uzcuai	113	57	SAB	SAB	NNP
cord-029813-o2uzcuai	113	58	Biotherapeutics	Biotherapeutics	NNPS
cord-029813-o2uzcuai	113	59	,	,	,
cord-029813-o2uzcuai	113	60	and	and	CC
cord-029813-o2uzcuai	113	61	Vir	Vir	NNP
cord-029813-o2uzcuai	113	62	.	.	.
cord-029813-o2uzcuai	114	1	The	the	DT
cord-029813-o2uzcuai	114	2	authors	author	NNS
cord-029813-o2uzcuai	114	3	have	have	VBP
cord-029813-o2uzcuai	114	4	no	no	DT
cord-029813-o2uzcuai	114	5	other	other	JJ
cord-029813-o2uzcuai	114	6	relevant	relevant	JJ
cord-029813-o2uzcuai	114	7	affiliations	affiliation	NNS
cord-029813-o2uzcuai	114	8	or	or	CC
cord-029813-o2uzcuai	114	9	financial	financial	JJ
cord-029813-o2uzcuai	114	10	involvement	involvement	NN
cord-029813-o2uzcuai	114	11	with	with	IN
cord-029813-o2uzcuai	114	12	any	any	DT
cord-029813-o2uzcuai	114	13	organization	organization	NN
cord-029813-o2uzcuai	114	14	or	or	CC
cord-029813-o2uzcuai	114	15	entity	entity	NN
cord-029813-o2uzcuai	114	16	with	with	IN
cord-029813-o2uzcuai	114	17	a	a	DT
cord-029813-o2uzcuai	114	18	financial	financial	JJ
cord-029813-o2uzcuai	114	19	interest	interest	NN
cord-029813-o2uzcuai	114	20	in	in	IN
cord-029813-o2uzcuai	114	21	or	or	CC
cord-029813-o2uzcuai	114	22	financial	financial	JJ
cord-029813-o2uzcuai	114	23	conflict	conflict	NN
cord-029813-o2uzcuai	114	24	with	with	IN
cord-029813-o2uzcuai	114	25	the	the	DT
cord-029813-o2uzcuai	114	26	subject	subject	JJ
cord-029813-o2uzcuai	114	27	matter	matter	NN
cord-029813-o2uzcuai	114	28	or	or	CC
cord-029813-o2uzcuai	114	29	materials	material	NNS
cord-029813-o2uzcuai	114	30	discussed	discuss	VBN
cord-029813-o2uzcuai	114	31	in	in	IN
cord-029813-o2uzcuai	114	32	the	the	DT
cord-029813-o2uzcuai	114	33	manuscript	manuscript	NN
cord-029813-o2uzcuai	114	34	apart	apart	RB
cord-029813-o2uzcuai	114	35	from	from	IN
cord-029813-o2uzcuai	114	36	those	those	DT
cord-029813-o2uzcuai	114	37	disclosed	disclose	VBN
cord-029813-o2uzcuai	114	38	.	.	.
cord-029813-o2uzcuai	115	1	No	no	DT
cord-029813-o2uzcuai	115	2	writing	writing	NN
cord-029813-o2uzcuai	115	3	assistance	assistance	NN
cord-029813-o2uzcuai	115	4	was	be	VBD
cord-029813-o2uzcuai	115	5	utilized	utilize	VBN
cord-029813-o2uzcuai	115	6	in	in	IN
cord-029813-o2uzcuai	115	7	the	the	DT
cord-029813-o2uzcuai	115	8	production	production	NN
cord-029813-o2uzcuai	115	9	of	of	IN
cord-029813-o2uzcuai	115	10	this	this	DT
cord-029813-o2uzcuai	115	11	manuscript	manuscript	NN
cord-029813-o2uzcuai	115	12	.	.	.
cord-029813-o2uzcuai	116	1	COVID-19	COVID-19	NNP
cord-029813-o2uzcuai	116	2	and	and	CC
cord-029813-o2uzcuai	116	3	coronaviral	coronaviral	NNP
cord-029813-o2uzcuai	116	4	hepatitis	hepatitis	NNP
cord-029813-o2uzcuai	116	5	:	:	:
cord-029813-o2uzcuai	116	6	evidence	evidence	NN
cord-029813-o2uzcuai	116	7	of	of	IN
cord-029813-o2uzcuai	116	8	collateral	collateral	JJ
cord-029813-o2uzcuai	116	9	damage	damage	NN
cord-029813-o2uzcuai	116	10	COVID-19	COVID-19	VBD
cord-029813-o2uzcuai	116	11	in	in	IN
cord-029813-o2uzcuai	116	12	homeless	homeless	JJ
cord-029813-o2uzcuai	116	13	populations	population	NNS
cord-029813-o2uzcuai	116	14	:	:	:
cord-029813-o2uzcuai	116	15	unique	unique	JJ
cord-029813-o2uzcuai	116	16	challenges	challenge	NNS
cord-029813-o2uzcuai	116	17	and	and	CC
cord-029813-o2uzcuai	116	18	opportunities	opportunity	NNS
cord-029813-o2uzcuai	117	1	A	a	DT
cord-029813-o2uzcuai	117	2	suspected	suspect	VBN
cord-029813-o2uzcuai	117	3	case	case	NN
cord-029813-o2uzcuai	117	4	of	of	IN
cord-029813-o2uzcuai	117	5	COVID-19	COVID-19	NNP
cord-029813-o2uzcuai	117	6	turned	turn	VBN
cord-029813-o2uzcuai	117	7	into	into	IN
cord-029813-o2uzcuai	117	8	a	a	DT
cord-029813-o2uzcuai	117	9	confirmed	confirm	VBN
cord-029813-o2uzcuai	117	10	case	case	NN
cord-029813-o2uzcuai	117	11	:	:	:
cord-029813-o2uzcuai	117	12	a	a	DT
cord-029813-o2uzcuai	117	13	case	case	NN
cord-029813-o2uzcuai	117	14	report	report	NN
cord-029813-o2uzcuai	117	15	Detection	Detection	NNP
cord-029813-o2uzcuai	117	16	of	of	IN
cord-029813-o2uzcuai	117	17	SARS	SARS	NNP
cord-029813-o2uzcuai	117	18	-	-	HYPH
cord-029813-o2uzcuai	117	19	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	117	20	in	in	IN
cord-029813-o2uzcuai	117	21	different	different	JJ
cord-029813-o2uzcuai	117	22	types	type	NNS
cord-029813-o2uzcuai	117	23	of	of	IN
cord-029813-o2uzcuai	117	24	clinical	clinical	JJ
cord-029813-o2uzcuai	117	25	specimens	specimen	NNS
cord-029813-o2uzcuai	118	1	The	the	DT
cord-029813-o2uzcuai	118	2	divergence	divergence	NN
cord-029813-o2uzcuai	118	3	between	between	IN
cord-029813-o2uzcuai	118	4	SARS	SARS	NNP
cord-029813-o2uzcuai	118	5	-	-	HYPH
cord-029813-o2uzcuai	118	6	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	118	7	and	and	CC
cord-029813-o2uzcuai	118	8	RaTG13	RaTG13	NNP
cord-029813-o2uzcuai	118	9	might	may	MD
cord-029813-o2uzcuai	118	10	be	be	VB
cord-029813-o2uzcuai	118	11	overestimated	overestimate	VBN
cord-029813-o2uzcuai	118	12	due	due	IN
cord-029813-o2uzcuai	118	13	to	to	IN
cord-029813-o2uzcuai	118	14	the	the	DT
cord-029813-o2uzcuai	118	15	extensive	extensive	JJ
cord-029813-o2uzcuai	118	16	RNA	RNA	NNP
cord-029813-o2uzcuai	118	17	modification	modification	NN
cord-029813-o2uzcuai	118	18	Pros	pro	NNS
cord-029813-o2uzcuai	118	19	and	and	CC
cord-029813-o2uzcuai	118	20	cons	con	NNS
cord-029813-o2uzcuai	118	21	of	of	IN
cord-029813-o2uzcuai	118	22	the	the	DT
cord-029813-o2uzcuai	118	23	application	application	NN
cord-029813-o2uzcuai	118	24	of	of	IN
cord-029813-o2uzcuai	118	25	evolutionary	evolutionary	JJ
cord-029813-o2uzcuai	118	26	theories	theory	NNS
cord-029813-o2uzcuai	118	27	to	to	IN
cord-029813-o2uzcuai	118	28	the	the	DT
cord-029813-o2uzcuai	118	29	evolution	evolution	NN
cord-029813-o2uzcuai	118	30	of	of	IN
cord-029813-o2uzcuai	118	31	SARS	SARS	NNP
cord-029813-o2uzcuai	118	32	-	-	HYPH
cord-029813-o2uzcuai	118	33	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	119	1	On	on	IN
cord-029813-o2uzcuai	119	2	the	the	DT
cord-029813-o2uzcuai	119	3	origin	origin	NN
cord-029813-o2uzcuai	119	4	and	and	CC
cord-029813-o2uzcuai	119	5	continuing	continue	VBG
cord-029813-o2uzcuai	119	6	evolution	evolution	NN
cord-029813-o2uzcuai	119	7	of	of	IN
cord-029813-o2uzcuai	119	8	SARS	SARS	NNP
cord-029813-o2uzcuai	119	9	-	-	HYPH
cord-029813-o2uzcuai	119	10	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	119	11	Prediction	Prediction	NNP
cord-029813-o2uzcuai	119	12	and	and	CC
cord-029813-o2uzcuai	119	13	analysis	analysis	NN
cord-029813-o2uzcuai	119	14	of	of	IN
cord-029813-o2uzcuai	119	15	key	key	JJ
cord-029813-o2uzcuai	119	16	protein	protein	NN
cord-029813-o2uzcuai	119	17	structures	structure	NNS
cord-029813-o2uzcuai	119	18	of	of	IN
cord-029813-o2uzcuai	119	19	2019-nCoV	2019-ncov	CD
cord-029813-o2uzcuai	120	1	Possible	possible	JJ
cord-029813-o2uzcuai	120	2	SARS	SARS	NNP
cord-029813-o2uzcuai	120	3	-	-	HYPH
cord-029813-o2uzcuai	120	4	coronavirus	coronavirus	NN
cord-029813-o2uzcuai	120	5	2	2	CD
cord-029813-o2uzcuai	120	6	inhibitor	inhibitor	NN
cord-029813-o2uzcuai	120	7	revealed	reveal	VBN
cord-029813-o2uzcuai	120	8	by	by	IN
cord-029813-o2uzcuai	120	9	simulated	simulated	JJ
cord-029813-o2uzcuai	120	10	molecular	molecular	JJ
cord-029813-o2uzcuai	120	11	docking	docking	NN
cord-029813-o2uzcuai	120	12	to	to	IN
cord-029813-o2uzcuai	120	13	viral	viral	JJ
cord-029813-o2uzcuai	120	14	main	main	JJ
cord-029813-o2uzcuai	120	15	protease	protease	NN
cord-029813-o2uzcuai	120	16	and	and	CC
cord-029813-o2uzcuai	120	17	host	host	NN
cord-029813-o2uzcuai	120	18	toll	toll	NN
cord-029813-o2uzcuai	120	19	-	-	HYPH
cord-029813-o2uzcuai	120	20	like	like	JJ
cord-029813-o2uzcuai	120	21	receptor	receptor	NN
cord-029813-o2uzcuai	121	1	The	the	DT
cord-029813-o2uzcuai	121	2	pharmacological	pharmacological	JJ
cord-029813-o2uzcuai	121	3	potential	potential	NN
cord-029813-o2uzcuai	121	4	of	of	IN
cord-029813-o2uzcuai	121	5	rutin	rutin	NN
cord-029813-o2uzcuai	121	6	Transmission	transmission	NN
cord-029813-o2uzcuai	121	7	and	and	CC
cord-029813-o2uzcuai	121	8	clinical	clinical	JJ
cord-029813-o2uzcuai	121	9	characteristics	characteristic	NNS
cord-029813-o2uzcuai	121	10	of	of	IN
cord-029813-o2uzcuai	121	11	asymptomatic	asymptomatic	JJ
cord-029813-o2uzcuai	121	12	patients	patient	NNS
cord-029813-o2uzcuai	121	13	with	with	IN
cord-029813-o2uzcuai	121	14	SARS	SARS	NNP
cord-029813-o2uzcuai	121	15	-	-	HYPH
cord-029813-o2uzcuai	121	16	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	121	17	infection	infection	NN
cord-029813-o2uzcuai	122	1	Temporal	temporal	JJ
cord-029813-o2uzcuai	122	2	dynamics	dynamic	NNS
cord-029813-o2uzcuai	122	3	in	in	IN
cord-029813-o2uzcuai	122	4	viral	viral	JJ
cord-029813-o2uzcuai	122	5	shedding	shedding	NN
cord-029813-o2uzcuai	122	6	and	and	CC
cord-029813-o2uzcuai	122	7	transmissibility	transmissibility	NN
cord-029813-o2uzcuai	122	8	of	of	IN
cord-029813-o2uzcuai	122	9	COVID-19	COVID-19	NNP
cord-029813-o2uzcuai	122	10	Severe	severe	JJ
cord-029813-o2uzcuai	122	11	acute	acute	JJ
cord-029813-o2uzcuai	122	12	respiratory	respiratory	JJ
cord-029813-o2uzcuai	122	13	syndrome	syndrome	NN
cord-029813-o2uzcuai	122	14	coronavirus-2	coronavirus-2	NN
cord-029813-o2uzcuai	123	1	(	(	-LRB-
cord-029813-o2uzcuai	123	2	SARS	SARS	NNP
cord-029813-o2uzcuai	123	3	-	-	HYPH
cord-029813-o2uzcuai	123	4	CoV-2	CoV-2	NNP
cord-029813-o2uzcuai	123	5	)	)	-RRB-
cord-029813-o2uzcuai	123	6	infection	infection	NN
cord-029813-o2uzcuai	123	7	:	:	:
cord-029813-o2uzcuai	123	8	let	let	VB
cord-029813-o2uzcuai	123	9	the	the	DT
cord-029813-o2uzcuai	123	10	virus	virus	NN
cord-029813-o2uzcuai	123	11	be	be	VB
cord-029813-o2uzcuai	123	12	its	-PRON-	PRP$
cord-029813-o2uzcuai	123	13	own	own	JJ
cord-029813-o2uzcuai	123	14	demise	demise	NN
cord-029813-o2uzcuai	123	15	Mechanism	mechanism	NN
cord-029813-o2uzcuai	123	16	of	of	IN
cord-029813-o2uzcuai	123	17	baricitinib	baricitinib	NN
cord-029813-o2uzcuai	123	18	supports	support	VBZ
cord-029813-o2uzcuai	123	19	artificial	artificial	JJ
cord-029813-o2uzcuai	123	20	intelligence	intelligence	NN
cord-029813-o2uzcuai	123	21	-	-	HYPH
cord-029813-o2uzcuai	123	22	predicted	predict	VBN
cord-029813-o2uzcuai	123	23	testing	testing	NN
cord-029813-o2uzcuai	123	24	in	in	IN
cord-029813-o2uzcuai	123	25	COVID-19	covid-19	CD
cord-029813-o2uzcuai	123	26	patients	patient	NNS