id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-349659-6drnriun	Grant, Benjamin D.	SARS-CoV-2 Coronavirus Nucleocapsid Antigen-Detecting Half-Strip Lateral Flow Assay Toward the Development of Point of Care Tests Using Commercially Available Reagents	2020-07-01		.txt	text/plain	3203	207	57	title: SARS-CoV-2 Coronavirus Nucleocapsid Antigen-Detecting Half-Strip Lateral Flow Assay Toward the Development of Point of Care Tests Using Commercially Available Reagents In this work, we present a half-strip LFA using commercially available antibodies for the detection of SARS-CoV-2. 10 Antigen detecting ELISAs were previously developed in 2004 for SARS-CoV-1, with limits of detection of approximately 50 pg/mL and clinical sensitivity as a function of days since onset that was significantly better than the useful time window for the current generation of SARS-CoV-2 serology assays. A dose response curve was generated for the half-strip LFA using two commercially available SARS-CoV-2 nucleocapsid (N) proteins, from Genemedi and Genscript. Analytical Chemistry pubs.acs.org/ac Article and determination of realistic limits of detection for a full strip LFA in multiple sample matrices will help point the way toward the best approach for an antigen detecting LFA for SARS-CoV-2. In this paper, we present a half-strip LFA for the detection of nucleocapsid protein of SARS-CoV-2.	./cache/cord-349659-6drnriun.txt	./txt/cord-349659-6drnriun.txt