id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-335289-m4u96x2v	Bhattacharya, Manojit	Development of epitope‐based peptide vaccine against novel coronavirus 2019 (SARS‐COV‐2): Immunoinformatics approach	2020-03-05		.txt	text/plain	1017	81	49	authors: Bhattacharya, Manojit; Sharma, Ashish R.; Patra, Prasanta; Ghosh, Pratik; Sharma, Garima; Patra, Bidhan C.; Lee, Sang‐Soo; Chakraborty, Chiranjib title: Development of epitope‐based peptide vaccine against novel coronavirus 2019 (SARS‐COV‐2): Immunoinformatics approach Therefore, as the situation was getting worse and worse, the need for designing a suitable peptide vaccine component against the SARS-COV-2 was growing. The amino acid sequence of the targeted protein on SARS-COV-2 was collected from the National Centre for Biotechnological Information (NCBI) database. We obtained a total of 34 sequential linear B-cell epitopes of varying lengths from the IEDB server within spike glycoprotein of SARS-COV-2. In this study, we linked the 13 MHC-I and 3 MHC-II antigenic epitopes with (EAAAK) 3 linker peptide to construct a vaccine component. Moreover, the molecular docking of vaccine components with the TLR-5 proves the significance and effectiveness of these epitopes as an ideal vaccine candidate against SARS-COV-2. Development of epitope-based peptide vaccine against novel coronavirus 2019 (SARS-COV-2): Immunoinformatics approach	./cache/cord-335289-m4u96x2v.txt	./txt/cord-335289-m4u96x2v.txt