id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-332080-923jpec0	Lai, Chih-Cheng	In vitro diagnostics of coronavirus disease 2019: technologies and application	2020-06-05		.txt	text/plain	1189	92	58	Abstract Laboratory-based diagnostic measures including virological and serological tests are essential for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, serological tests cannot confirm SARS-CoV-2, and results will be false-negative when antibody concentrations fall below detection limits. (Hangzhou Bigfish Bio-tech Co., Ltd., Zhejiang, China) was recently registered 127 as a CE-IVD for detecting SARS-CoV-2 ORF-1ab and N genes in 128 nasopharyngeal swabs, sputum, and BAL fluids. The 145 performance of the Xpress SARS-CoV-2 test was clinically evaluated in 146 patients with respiratory illnesses from whom contrived nasopharyngeal swab 147 samples were collected into viral transport media. Serological tests that can detect SARS-CoV-2 IgG-IgM antibodies are simpler 248 than rRT-PCR, and do not require complicated equipment and protocols 249 (Table 3) . During the previous SARS 251 epidemic, the IgM antibody was the first line of defense during viral infections 252 and was detectable in blood samples from patients after 3 -6 days. Dynamics of 617 anti-SARS-Cov-2 IgM and IgG antibodies among COVID-19 patients	./cache/cord-332080-923jpec0.txt	./txt/cord-332080-923jpec0.txt