id author title date pages extension mime words sentences flesch summary cache txt cord-313344-rqvi2ksc Farcas, Gabriella A. Fatal Severe Acute Respiratory Syndrome Is Associated with Multiorgan Involvement by Coronavirus 2005-01-15 .txt text/plain 2427 104 46 Severe acute respiratory syndrome (SARS) is characterized by pulmonary compromise; however, patients often have evidence of other organ dysfunction that may reflect extrapulmonary dissemination of SARS coronavirus (SARS-CoV). The purpose of the present study was to investigate the presence of SARS-CoV, the degree of viral dissemination, and the viral loads in multiple organ samples from all patients who died of SARS during the Toronto outbreak (March to September 2003) and underwent a postmortem examination and compare the results with those found in patients who died of other causes during the outbreak. A total of 212 discrete postmortem organ samples, including lung, liver, spleen, kidney, small bowel, large bowel, lymph nodes, heart, and skeletal muscle, were prospectively collected from the 21 patients who died of SARS and underwent autopsies. ./cache/cord-313344-rqvi2ksc.txt ./txt/cord-313344-rqvi2ksc.txt