id author title date pages extension mime words sentences flesch summary cache txt cord-302584-fwdpzv85 Zhu, Ying Isolation of Virus from a SARS Patient and Genome-wide Analysis of Genetic Mutations Related to Pathogenesis and Epidemiology from 47 SARS-CoV Isolates 2005-01-01 .txt text/plain 3429 170 54 title: Isolation of Virus from a SARS Patient and Genome-wide Analysis of Genetic Mutations Related to Pathogenesis and Epidemiology from 47 SARS-CoV Isolates Despite the fact that the SARS-CoV can cause an atypical and fatal form of pneumonia, the genome structure, gene expression pattern, and protein profiles of the virus are similar to those of other conventional coronaviruses [17] , which are only responsible for mild respiratory tract infections in a wide range of animals including humans, pigs, cows, mice, cats, and birds [10, 19] . In this report, we described the isolation of a new SARS-CoV strain (WHU) from a patient in Hubei Province, China during the late period of SARS outbreak. Comparative study of genetic characterization and nucleotide variation of all known SARS-CoV offers insights into understanding functions of the viral genes and revealing the evolution trends of the virus. ./cache/cord-302584-fwdpzv85.txt ./txt/cord-302584-fwdpzv85.txt