id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-274841-rcdoewwv	Tay, Matthew Zirui	The trinity of COVID-19: immunity, inflammation and intervention	2020-04-28		.txt	text/plain	7186	383	43	Monoclonal antibodies targeting the When severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects cells expressing the surface receptors angiotensin-converting enzyme 2 (ACE2) and TMPRSS2, the active replication and release of the virus cause the host cell to undergo pyroptosis and release damageassociated molecular patterns, including ATP, nucleic acids and ASC oligomers. While there are no clinical trials specifically testing these drugs against COVID-19 at the time of writing, when camostat mesylate was tested on SARS-CoV-2 isolated from a patient, it prevented entry of the virus into lung cells 44, 50 . Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice Neutralizing antibodies in patients with severe acute respiratory syndrome-associated Nature reviews | Immunology coronavirus infection	./cache/cord-274841-rcdoewwv.txt	./txt/cord-274841-rcdoewwv.txt