id author title date pages extension mime words sentences flesch summary cache txt cord-274141-vujx538o Chinsembu, Kazhila C. Coronaviruses and Nature’s Pharmacy for the Relief of Coronavirus Disease 2019 2020-10-06 .txt text/plain 11338 676 53 De Clercq (2005 suggested that it was feasible to develop SARS-CoV fusion inhibitors analogous to enfuvirtide, a linear 36-amino acid synthetic peptide marketed under the trade name Fuzeon, an approved anti-HIV drug that inhibits the entry of the virus into cells. It was hypothesized that specific flavonoids, such as quercetin, hesperetin, and myricetin (7) and their glycosylated derivatives, may play an effective role in inhibiting SARS-CoV entry into host cells, specifically by binding with high affinity to the spike protein, helicase, and protease sites on the ACE receptor (Ngwa et al. Although the ongoing SARS-CoV-2 global pandemic should remind scientists that current options for treating life-threatening zoonotic coronavirus infections are very limited , medicinal plants offer a strong pipeline for the discovery of novel lead compounds that can be converted into new drugs to treat COVID-19. ./cache/cord-274141-vujx538o.txt ./txt/cord-274141-vujx538o.txt