id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-256217-fnjer0e0	Neri, Piergiorgio	COVID-19 and the eye immunity: lesson learned from the past and possible new therapeutic insights	2020-04-20		.txt	text/plain	1928	88	43	Corona virus represents nowadays the hot topic in the scientific world due to the outbreak of a novel serotype formerly named coronavirus disease (COVID)-19 and now identified as severe acute respiratory syndrome (SARS)-COV-2 [1] . Although ECOR was used to study retinal degeneration specifically, it might represent a possible experimental model for interesting speculations on how to approach severe SARS-COV-2 pulmonary complications. Looking at the ECOR model, it gives the impression that coronavirus creates two different phases: the first is represented by the primary infection which induces the triggering of the immune system, while the second phase is likely to be an autoimmune disease where the role of the severe postviral inflammation represents a severe occurrence worth of prompt intervention. Albeit it is true that anti-IL-6 receptor monoclonal antibody has given promising results for the control of severe SARS-COV-2 pneumonia, it is interesting to notice that retinal degeneration in ECOR is associated with an evident increase in TNF-alpha, as well as soluble TNFR2, inducing an anomaly of TNF-alpha signaling [12] .	./cache/cord-256217-fnjer0e0.txt	./txt/cord-256217-fnjer0e0.txt