id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-150183-zzzyewjb	Phillips, J. C.	Synchronized Attachment and the Darwinian Evolution of Coronaviruses CoV-1 and CoV-2	2020-08-27		.txt	text/plain	2483	154	55	These are (CoV-1 site numbering from Uniprot P59594): 546Gln to Leu; 556 and 561Ser to Ala; and 568Ser to Leu. The differences associated with each of these mutations are hydropathically large (~50-100 in the MZ scale [4] ; all 20 amino acids span a range from most hydrophilic to most hydrophobic of 170). The central hydrophilic level set, absent from CoV-1 and present in CoV-2, is our main result ( There is an excellent review of the principles of self-organized criticality in living matter [3] . Some readers may be interested in the connections between hydropathic scaling theory of proteins and the more general synchronization of complex networks. Now that we are in the genomic age, with a very large sequence data base available for many proteins and many species, the discovery of these 20 fractals [5, 13] opens a new biophysics field of accurate thermodynamic analysis of small but medically important evolutionary differences.	./cache/cord-150183-zzzyewjb.txt	./txt/cord-150183-zzzyewjb.txt