id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-345014-qp13h0un	Stein, Richard Albert	The 2019 coronavirus: Learning curves, lessons, and the weakest link	2020-03-13		.txt	text/plain	2268	155	57	14 In the most recent of the three coronavirus outbreaks, several clusters of patients with pneumonia started to be reported on December 8, 2019 from Wuhan, China, and most of them were epidemiologically linked to the Huanan Seafood Wholesale Market. 24, 25 The virus shares >70% genetic similarity with the 2002-2003 SARS-CoV strain, 5 is most closely related to coronaviruses of bat origin, 17 its spike glycoprotein gene appears to have emerged by recombination between a bat coronavirus and a coronavirus of unknown origins, and relative synonymous codon usage bias analyses indicate that snakes may be a potential reservoir. 26 The SARS-CoV spike protein receptor binds the angiotensin-converting enzyme 2 (ACE2) on host cells, an interaction that shapes cross-species and human-to-human transmission. 10,58-60 Every outbreak brings something new, provides opportunities to reap the benefits gained from past epidemics and pandemics, and provides novel lessons that will shape the framework to manage emerging infectious diseases. The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health -the latest 2019 novel coronavirus outbreak in Wuhan, China	./cache/cord-345014-qp13h0un.txt	./txt/cord-345014-qp13h0un.txt