id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-311847-2czqs84q	Pennisi, Manuela	SARS-CoV-2 and the Nervous System: From Clinical Features to Molecular Mechanisms	2020-07-31		.txt	text/plain	9002	433	40	Increasing evidence suggests that Severe Acute Respiratory Syndrome-coronavirus-2 (SARS-CoV-2) can also invade the central nervous system (CNS). Although there are limitations in the epidemiological studies carried on COVID-19, as well as limited case records for determining the actual incidence of these complications, some patients reported neurological symptoms, but clinical findings and pathogenic features have not yet systematically addressed. The aims of this review are i) to summarize the available information on the relationship between CoVs and the nervous system, ii) to identify the potential targets and routes of entry of SARS-CoV-2 into the nervous system, and iii) to describe the range of the neurological features reported to date in patients with COVID-19 and the proposed pathogenic mechanisms. Indeed, no axonal transport of SARS-CoV-2 to the brain has been demonstrated in the hamster model during the first two weeks after infection [89] , and no viral accumulation or persistence has been reported in cerebral olfactory regions of autopsy material from patients with COVID-19 [90] .	./cache/cord-311847-2czqs84q.txt	./txt/cord-311847-2czqs84q.txt