id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-344835-iivry1ou	Tsoumakidou, Maria	Novel insights into the aetiology and pathophysiology of increased airway inflammation during COPD exacerbations	2006-05-22		.txt	text/plain	5058	261	31	A significant number of studies in stable COPD patients suggest that airway bacterial infections are associated with increased airway inflammation (18) (19) (20) (21) . Soler et al used protected specimen brush and bronchoalveolar lavage sampling to determine inflammatory cell counts, levels of cytokines concentrations and microbial patterns in stable COPD patients and found that increased neutrophils and tumour necrosis factor-alpha (TNFalpha) levels may be related to bronchial colonization [18] . The group of J Wedzicha showed that viral infections might be implicated in the mechanisms of increased airway and possibly systemic inflammation during COPD exacerbations. Haemophilus influenzae from patients with chronic obstructive pulmonary disease exacerbation induce more inflammation than colonizers Airway inflammation and bronchial microbial patterns in patients with stable chronic obstructive pulmonary disease Association of viral and Mycoplasma pneumoniae infections with acute respiratory illness in patients with chronic obstructive pulmonary diseases Airway inflammation during stable and acutely exacerbated chronic obstructive pulmonary disease	./cache/cord-344835-iivry1ou.txt	./txt/cord-344835-iivry1ou.txt