id author title date pages extension mime words sentences flesch summary cache txt cord-340851-lnv8yi9l Perkins, Alex Optimal control of the COVID-19 pandemic with non-pharmaceutical interventions 2020-04-23 .txt text/plain 6951 407 55 To characterize a range of possible strategies for control and to understand their consequences, we performed an optimal control analysis of a mathematical model of SARS-CoV-2 transmission. Our results also highlight that the potential scope for controlling COVID-19 until a vaccine is available depends on epidemiological parameters about which there is still considerable uncertainty, including the basic reproduction number and the effectiveness of social distancing. Strategies for successfully controlling COVID-19 until then will depend on a suite of non-pharmaceutical interventions (NPIs) [3] , including some degree of social distancing but also diagnostic testing, contact tracing, and case isolation [5] . Because they are similar to the components of the objective functional but more easily interpretable, we describe effects of model parameters on t1 t0 D(t)dt (cumulative deaths) and t1 t0 u(t)dt (cumulative time under control). ./cache/cord-340851-lnv8yi9l.txt ./txt/cord-340851-lnv8yi9l.txt