id author title date pages extension mime words sentences flesch summary cache txt cord-267416-4dzqzwx0 Bolzoni, Luca Time-optimal control strategies in SIR epidemic models 2017-10-31 .txt text/plain 6886 442 58 Abstract We investigate the time-optimal control problem in SIR (Susceptible-Infected-Recovered) epidemic models, focusing on different control policies: vaccination, isolation, culling, and reduction of transmission. On the other hand, the optimal control theory has been widely applied to solve the problem of minimizing the total number of infected individuals (or the total infectious burden) in basic SIR (Susceptible-Infected-Recovered) epidemic models by means of different control policies, such as: the implementation of emergency prophylactic vaccination plans, the isolation of infected individuals, the reduction of disease transmission through the limitation of contacts between individuals, and non-selective culling [19] [20] [21] [22] [23] [24] [25] . Here, by using simple SIR models in an optimal control framework [26] , we thoroughly investigate the problem of minimizing the epidemic duration by using prophylactic vaccination, isolation, non-selective culling, or reduction of transmission controls. ./cache/cord-267416-4dzqzwx0.txt ./txt/cord-267416-4dzqzwx0.txt