id	sid	tid	token	lemma	pos
cord-016903-z2vqfq98	1	1	key	key	NNP
cord-016903-z2vqfq98	1	2	:	:	:
cord-016903-z2vqfq98	1	3	cord-016903-z2vqfq98	cord-016903-z2vqfq98	ADD
cord-016903-z2vqfq98	2	1	authors	author	NNS
cord-016903-z2vqfq98	2	2	:	:	:
cord-016903-z2vqfq98	2	3	Herndler	Herndler	NNP
cord-016903-z2vqfq98	2	4	-	-	HYPH
cord-016903-z2vqfq98	2	5	Brandstetter	Brandstetter	NNP
cord-016903-z2vqfq98	2	6	,	,	,
cord-016903-z2vqfq98	2	7	Dietmar	Dietmar	NNP
cord-016903-z2vqfq98	2	8	;	;	:
cord-016903-z2vqfq98	2	9	Grubeck	Grubeck	NNP
cord-016903-z2vqfq98	2	10	-	-	HYPH
cord-016903-z2vqfq98	2	11	Loebenstein	Loebenstein	NNP
cord-016903-z2vqfq98	2	12	,	,	,
cord-016903-z2vqfq98	2	13	Beatrix	Beatrix	NNP
cord-016903-z2vqfq98	2	14	title	title	NN
cord-016903-z2vqfq98	2	15	:	:	:
cord-016903-z2vqfq98	2	16	The	the	DT
cord-016903-z2vqfq98	2	17	Efficacy	Efficacy	NNP
cord-016903-z2vqfq98	2	18	of	of	IN
cord-016903-z2vqfq98	2	19	Vaccines	vaccine	NNS
cord-016903-z2vqfq98	2	20	to	to	TO
cord-016903-z2vqfq98	2	21	Prevent	prevent	VB
cord-016903-z2vqfq98	2	22	Infectious	infectious	JJ
cord-016903-z2vqfq98	2	23	Diseases	Diseases	NNPS
cord-016903-z2vqfq98	2	24	in	in	IN
cord-016903-z2vqfq98	2	25	the	the	DT
cord-016903-z2vqfq98	2	26	Elderly	elderly	JJ
cord-016903-z2vqfq98	2	27	date	date	NN
cord-016903-z2vqfq98	2	28	:	:	:
cord-016903-z2vqfq98	2	29	2007	2007	CD
cord-016903-z2vqfq98	2	30	journal	journal	NNP
cord-016903-z2vqfq98	2	31	:	:	:
cord-016903-z2vqfq98	3	1	Immunosenescence	Immunosenescence	NNP
cord-016903-z2vqfq98	3	2	DOI	DOI	NNP
cord-016903-z2vqfq98	3	3	:	:	:
cord-016903-z2vqfq98	4	1	10.1007/978	10.1007/978	LS
cord-016903-z2vqfq98	4	2	-	-	HYPH
cord-016903-z2vqfq98	4	3	0	0	CD
cord-016903-z2vqfq98	4	4	-	-	HYPH
cord-016903-z2vqfq98	4	5	387	387	CD
cord-016903-z2vqfq98	4	6	-	-	HYPH
cord-016903-z2vqfq98	4	7	76842	76842	CD
cord-016903-z2vqfq98	4	8	-	-	HYPH
cord-016903-z2vqfq98	4	9	7_10	7_10	CD
cord-016903-z2vqfq98	5	1	sha	sha	NNP
cord-016903-z2vqfq98	5	2	:	:	:
cord-016903-z2vqfq98	6	1	8d068a34263f2e0e6479960107bab9aab48d1024	8d068a34263f2e0e6479960107bab9aab48d1024	CD
cord-016903-z2vqfq98	6	2	doc_id	doc_id	CD
cord-016903-z2vqfq98	6	3	:	:	:
cord-016903-z2vqfq98	6	4	16903	16903	CD
cord-016903-z2vqfq98	6	5	cord_uid	cord_uid	FW
cord-016903-z2vqfq98	6	6	:	:	:
cord-016903-z2vqfq98	7	1	z2vqfq98	z2vqfq98	NNP
cord-016903-z2vqfq98	7	2	Infectious	infectious	JJ
cord-016903-z2vqfq98	7	3	diseases	disease	NNS
cord-016903-z2vqfq98	7	4	still	still	RB
cord-016903-z2vqfq98	7	5	represent	represent	VBP
cord-016903-z2vqfq98	7	6	a	a	DT
cord-016903-z2vqfq98	7	7	major	major	JJ
cord-016903-z2vqfq98	7	8	challenge	challenge	NN
cord-016903-z2vqfq98	7	9	to	to	IN
cord-016903-z2vqfq98	7	10	human	human	JJ
cord-016903-z2vqfq98	7	11	progress	progress	NN
cord-016903-z2vqfq98	7	12	and	and	CC
cord-016903-z2vqfq98	7	13	survival	survival	NN
cord-016903-z2vqfq98	7	14	.	.	.
cord-016903-z2vqfq98	8	1	Especially	especially	RB
cord-016903-z2vqfq98	8	2	elderly	elderly	JJ
cord-016903-z2vqfq98	8	3	persons	person	NNS
cord-016903-z2vqfq98	8	4	are	be	VBP
cord-016903-z2vqfq98	8	5	more	more	RBR
cord-016903-z2vqfq98	8	6	frequently	frequently	RB
cord-016903-z2vqfq98	8	7	and	and	CC
cord-016903-z2vqfq98	8	8	severely	severely	RB
cord-016903-z2vqfq98	8	9	affected	affect	VBN
cord-016903-z2vqfq98	8	10	by	by	IN
cord-016903-z2vqfq98	8	11	infectious	infectious	JJ
cord-016903-z2vqfq98	8	12	diseases	disease	NNS
cord-016903-z2vqfq98	8	13	and	and	CC
cord-016903-z2vqfq98	8	14	they	-PRON-	PRP
cord-016903-z2vqfq98	8	15	display	display	VBP
cord-016903-z2vqfq98	8	16	distinct	distinct	JJ
cord-016903-z2vqfq98	8	17	features	feature	NNS
cord-016903-z2vqfq98	8	18	with	with	IN
cord-016903-z2vqfq98	8	19	respect	respect	NN
cord-016903-z2vqfq98	8	20	to	to	IN
cord-016903-z2vqfq98	8	21	clinical	clinical	JJ
cord-016903-z2vqfq98	8	22	presentation	presentation	NN
cord-016903-z2vqfq98	8	23	and	and	CC
cord-016903-z2vqfq98	8	24	treatment	treatment	NN
cord-016903-z2vqfq98	8	25	.	.	.
cord-016903-z2vqfq98	9	1	Although	although	IN
cord-016903-z2vqfq98	9	2	vaccinations	vaccination	NNS
cord-016903-z2vqfq98	9	3	are	be	VBP
cord-016903-z2vqfq98	9	4	considered	consider	VBN
cord-016903-z2vqfq98	9	5	a	a	DT
cord-016903-z2vqfq98	9	6	vital	vital	JJ
cord-016903-z2vqfq98	9	7	medical	medical	JJ
cord-016903-z2vqfq98	9	8	procedure	procedure	NN
cord-016903-z2vqfq98	9	9	for	for	IN
cord-016903-z2vqfq98	9	10	preventing	prevent	VBG
cord-016903-z2vqfq98	9	11	morbidity	morbidity	NN
cord-016903-z2vqfq98	9	12	and	and	CC
cord-016903-z2vqfq98	9	13	mortality	mortality	NN
cord-016903-z2vqfq98	9	14	caused	cause	VBN
cord-016903-z2vqfq98	9	15	by	by	IN
cord-016903-z2vqfq98	9	16	infectious	infectious	JJ
cord-016903-z2vqfq98	9	17	diseases	disease	NNS
cord-016903-z2vqfq98	9	18	,	,	,
cord-016903-z2vqfq98	9	19	the	the	DT
cord-016903-z2vqfq98	9	20	protective	protective	JJ
cord-016903-z2vqfq98	9	21	effect	effect	NN
cord-016903-z2vqfq98	9	22	of	of	IN
cord-016903-z2vqfq98	9	23	vaccinations	vaccination	NNS
cord-016903-z2vqfq98	9	24	is	be	VBZ
cord-016903-z2vqfq98	9	25	abrogated	abrogate	VBN
cord-016903-z2vqfq98	9	26	in	in	IN
cord-016903-z2vqfq98	9	27	elderly	elderly	JJ
cord-016903-z2vqfq98	9	28	persons	person	NNS
cord-016903-z2vqfq98	9	29	.	.	.
cord-016903-z2vqfq98	10	1	This	this	DT
cord-016903-z2vqfq98	10	2	is	be	VBZ
cord-016903-z2vqfq98	10	3	due	due	JJ
cord-016903-z2vqfq98	10	4	to	to	IN
cord-016903-z2vqfq98	10	5	a	a	DT
cord-016903-z2vqfq98	10	6	decline	decline	NN
cord-016903-z2vqfq98	10	7	in	in	IN
cord-016903-z2vqfq98	10	8	the	the	DT
cord-016903-z2vqfq98	10	9	functions	function	NNS
cord-016903-z2vqfq98	10	10	of	of	IN
cord-016903-z2vqfq98	10	11	the	the	DT
cord-016903-z2vqfq98	10	12	immune	immune	JJ
cord-016903-z2vqfq98	10	13	system	system	NN
cord-016903-z2vqfq98	10	14	referred	refer	VBD
cord-016903-z2vqfq98	10	15	to	to	IN
cord-016903-z2vqfq98	10	16	as	as	RB
cord-016903-z2vqfq98	10	17	immunosenescence	immunosenescence	NNP
cord-016903-z2vqfq98	10	18	.	.	.
cord-016903-z2vqfq98	11	1	The	the	DT
cord-016903-z2vqfq98	11	2	first	first	JJ
cord-016903-z2vqfq98	11	3	part	part	NN
cord-016903-z2vqfq98	11	4	of	of	IN
cord-016903-z2vqfq98	11	5	this	this	DT
cord-016903-z2vqfq98	11	6	chapter	chapter	NN
cord-016903-z2vqfq98	11	7	will	will	MD
cord-016903-z2vqfq98	11	8	therefore	therefore	RB
cord-016903-z2vqfq98	11	9	summarize	summarize	VB
cord-016903-z2vqfq98	11	10	the	the	DT
cord-016903-z2vqfq98	11	11	status	status	NN
cord-016903-z2vqfq98	11	12	quo	quo	NN
cord-016903-z2vqfq98	11	13	of	of	IN
cord-016903-z2vqfq98	11	14	the	the	DT
cord-016903-z2vqfq98	11	15	efficacy	efficacy	NN
cord-016903-z2vqfq98	11	16	of	of	IN
cord-016903-z2vqfq98	11	17	vaccines	vaccine	NNS
cord-016903-z2vqfq98	11	18	in	in	IN
cord-016903-z2vqfq98	11	19	preventing	prevent	VBG
cord-016903-z2vqfq98	11	20	morbidity	morbidity	NN
cord-016903-z2vqfq98	11	21	and	and	CC
cord-016903-z2vqfq98	11	22	mortality	mortality	NN
cord-016903-z2vqfq98	11	23	caused	cause	VBN
cord-016903-z2vqfq98	11	24	by	by	IN
cord-016903-z2vqfq98	11	25	typical	typical	JJ
cord-016903-z2vqfq98	11	26	infectious	infectious	JJ
cord-016903-z2vqfq98	11	27	diseases	disease	NNS
cord-016903-z2vqfq98	11	28	in	in	IN
cord-016903-z2vqfq98	11	29	the	the	DT
cord-016903-z2vqfq98	11	30	elderly	elderly	JJ
cord-016903-z2vqfq98	11	31	,	,	,
cord-016903-z2vqfq98	11	32	such	such	JJ
cord-016903-z2vqfq98	11	33	as	as	IN
cord-016903-z2vqfq98	11	34	influenza	influenza	NN
cord-016903-z2vqfq98	11	35	,	,	,
cord-016903-z2vqfq98	11	36	pneumonia	pneumonia	NN
cord-016903-z2vqfq98	11	37	and	and	CC
cord-016903-z2vqfq98	11	38	tuberculosis	tuberculosis	NN
cord-016903-z2vqfq98	11	39	.	.	.
cord-016903-z2vqfq98	12	1	The	the	DT
cord-016903-z2vqfq98	12	2	second	second	JJ
cord-016903-z2vqfq98	12	3	part	part	NN
cord-016903-z2vqfq98	12	4	will	will	MD
cord-016903-z2vqfq98	12	5	then	then	RB
cord-016903-z2vqfq98	12	6	elucidate	elucidate	VB
cord-016903-z2vqfq98	12	7	the	the	DT
cord-016903-z2vqfq98	12	8	underlying	underlie	VBG
cord-016903-z2vqfq98	12	9	age	age	NN
cord-016903-z2vqfq98	12	10	-	-	HYPH
cord-016903-z2vqfq98	12	11	related	relate	VBN
cord-016903-z2vqfq98	12	12	mechanisms	mechanism	NNS
cord-016903-z2vqfq98	12	13	which	which	WDT
cord-016903-z2vqfq98	12	14	may	may	MD
cord-016903-z2vqfq98	12	15	contribute	contribute	VB
cord-016903-z2vqfq98	12	16	to	to	IN
cord-016903-z2vqfq98	12	17	the	the	DT
cord-016903-z2vqfq98	12	18	decreased	decrease	VBN
cord-016903-z2vqfq98	12	19	efficacy	efficacy	NN
cord-016903-z2vqfq98	12	20	of	of	IN
cord-016903-z2vqfq98	12	21	vaccines	vaccine	NNS
cord-016903-z2vqfq98	12	22	.	.	.
cord-016903-z2vqfq98	13	1	Based	base	VBN
cord-016903-z2vqfq98	13	2	on	on	IN
cord-016903-z2vqfq98	13	3	the	the	DT
cord-016903-z2vqfq98	13	4	complex	complex	JJ
cord-016903-z2vqfq98	13	5	mechanisms	mechanism	NNS
cord-016903-z2vqfq98	13	6	involved	involve	VBN
cord-016903-z2vqfq98	13	7	in	in	IN
cord-016903-z2vqfq98	13	8	immunosenescence	immunosenescence	NN
cord-016903-z2vqfq98	13	9	,	,	,
cord-016903-z2vqfq98	13	10	strategies	strategy	NNS
cord-016903-z2vqfq98	13	11	will	will	MD
cord-016903-z2vqfq98	13	12	be	be	VB
cord-016903-z2vqfq98	13	13	outlined	outline	VBN
cord-016903-z2vqfq98	13	14	which	which	WDT
cord-016903-z2vqfq98	13	15	may	may	MD
cord-016903-z2vqfq98	13	16	be	be	VB
cord-016903-z2vqfq98	13	17	succesfful	succesfful	JJ
cord-016903-z2vqfq98	13	18	in	in	IN
cord-016903-z2vqfq98	13	19	enhancing	enhance	VBG
cord-016903-z2vqfq98	13	20	protective	protective	JJ
cord-016903-z2vqfq98	13	21	immune	immune	JJ
cord-016903-z2vqfq98	13	22	responses	response	NNS
cord-016903-z2vqfq98	13	23	following	follow	VBG
cord-016903-z2vqfq98	13	24	vaccination	vaccination	NN
cord-016903-z2vqfq98	13	25	in	in	IN
cord-016903-z2vqfq98	13	26	elderly	elderly	JJ
cord-016903-z2vqfq98	13	27	persons	person	NNS
cord-016903-z2vqfq98	13	28	.	.	.
cord-016903-z2vqfq98	14	1	With	with	IN
cord-016903-z2vqfq98	14	2	respect	respect	NN
cord-016903-z2vqfq98	14	3	to	to	IN
cord-016903-z2vqfq98	14	4	the	the	DT
cord-016903-z2vqfq98	14	5	current	current	JJ
cord-016903-z2vqfq98	14	6	demographic	demographic	JJ
cord-016903-z2vqfq98	14	7	development	development	NN
cord-016903-z2vqfq98	14	8	in	in	IN
cord-016903-z2vqfq98	14	9	many	many	JJ
cord-016903-z2vqfq98	14	10	countries	country	NNS
cord-016903-z2vqfq98	14	11	,	,	,
cord-016903-z2vqfq98	14	12	including	include	VBG
cord-016903-z2vqfq98	14	13	the	the	DT
cord-016903-z2vqfq98	14	14	European	European	NNP
cord-016903-z2vqfq98	14	15	Union	Union	NNP
cord-016903-z2vqfq98	14	16	and	and	CC
cord-016903-z2vqfq98	14	17	the	the	DT
cord-016903-z2vqfq98	14	18	United	United	NNP
cord-016903-z2vqfq98	14	19	States	States	NNP
cord-016903-z2vqfq98	14	20	of	of	IN
cord-016903-z2vqfq98	14	21	America	America	NNP
cord-016903-z2vqfq98	14	22	,	,	,
cord-016903-z2vqfq98	14	23	infectious	infectious	JJ
cord-016903-z2vqfq98	14	24	diseases	disease	NNS
cord-016903-z2vqfq98	14	25	in	in	IN
cord-016903-z2vqfq98	14	26	geriatric	geriatric	JJ
cord-016903-z2vqfq98	14	27	patients	patient	NNS
cord-016903-z2vqfq98	14	28	are	be	VBP
cord-016903-z2vqfq98	14	29	becoming	become	VBG
cord-016903-z2vqfq98	14	30	an	an	DT
cord-016903-z2vqfq98	14	31	increasingly	increasingly	RB
cord-016903-z2vqfq98	14	32	important	important	JJ
cord-016903-z2vqfq98	14	33	issue	issue	NN
cord-016903-z2vqfq98	14	34	.	.	.
cord-016903-z2vqfq98	15	1	Infections	infection	NNS
cord-016903-z2vqfq98	15	2	in	in	IN
cord-016903-z2vqfq98	15	3	elderly	elderly	JJ
cord-016903-z2vqfq98	15	4	persons	person	NNS
cord-016903-z2vqfq98	15	5	are	be	VBP
cord-016903-z2vqfq98	15	6	not	not	RB
cord-016903-z2vqfq98	15	7	only	only	RB
cord-016903-z2vqfq98	15	8	more	more	RBR
cord-016903-z2vqfq98	15	9	frequent	frequent	JJ
cord-016903-z2vqfq98	15	10	and	and	CC
cord-016903-z2vqfq98	15	11	more	more	RBR
cord-016903-z2vqfq98	15	12	severe	severe	JJ
cord-016903-z2vqfq98	15	13	,	,	,
cord-016903-z2vqfq98	15	14	but	but	CC
cord-016903-z2vqfq98	15	15	they	-PRON-	PRP
cord-016903-z2vqfq98	15	16	also	also	RB
cord-016903-z2vqfq98	15	17	have	have	VBP
cord-016903-z2vqfq98	15	18	distinct	distinct	JJ
cord-016903-z2vqfq98	15	19	features	feature	NNS
cord-016903-z2vqfq98	15	20	regarding	regard	VBG
cord-016903-z2vqfq98	15	21	clinical	clinical	JJ
cord-016903-z2vqfq98	15	22	presentation	presentation	NN
cord-016903-z2vqfq98	15	23	,	,	,
cord-016903-z2vqfq98	15	24	microbial	microbial	JJ
cord-016903-z2vqfq98	15	25	epidemiology	epidemiology	NN
cord-016903-z2vqfq98	15	26	and	and	CC
cord-016903-z2vqfq98	15	27	treatment	treatment	NN
cord-016903-z2vqfq98	15	28	.	.	.
cord-016903-z2vqfq98	16	1	Urinary	urinary	JJ
cord-016903-z2vqfq98	16	2	tract	tract	NN
cord-016903-z2vqfq98	16	3	infections	infection	NNS
cord-016903-z2vqfq98	16	4	,	,	,
cord-016903-z2vqfq98	16	5	lower	low	JJR
cord-016903-z2vqfq98	16	6	respiratory	respiratory	JJ
cord-016903-z2vqfq98	16	7	tract	tract	NN
cord-016903-z2vqfq98	16	8	infections	infection	NNS
cord-016903-z2vqfq98	16	9	,	,	,
cord-016903-z2vqfq98	16	10	skin	skin	NN
cord-016903-z2vqfq98	16	11	and	and	CC
cord-016903-z2vqfq98	16	12	soft	soft	JJ
cord-016903-z2vqfq98	16	13	tissue	tissue	NN
cord-016903-z2vqfq98	16	14	infections	infection	NNS
cord-016903-z2vqfq98	16	15	,	,	,
cord-016903-z2vqfq98	16	16	infective	infective	JJ
cord-016903-z2vqfq98	16	17	endocarditis	endocarditis	NN
cord-016903-z2vqfq98	16	18	,	,	,
cord-016903-z2vqfq98	16	19	bacterial	bacterial	JJ
cord-016903-z2vqfq98	16	20	meningitis	meningitis	NN
cord-016903-z2vqfq98	16	21	,	,	,
cord-016903-z2vqfq98	16	22	tuberculosis	tuberculosis	NN
cord-016903-z2vqfq98	16	23	and	and	CC
cord-016903-z2vqfq98	16	24	herpes	herpes	NN
cord-016903-z2vqfq98	16	25	roster	roster	NN
cord-016903-z2vqfq98	16	26	appear	appear	VBP
cord-016903-z2vqfq98	16	27	to	to	TO
cord-016903-z2vqfq98	16	28	have	have	VB
cord-016903-z2vqfq98	16	29	a	a	DT
cord-016903-z2vqfq98	16	30	higher	high	JJR
cord-016903-z2vqfq98	16	31	prevalence	prevalence	NN
cord-016903-z2vqfq98	16	32	in	in	IN
cord-016903-z2vqfq98	16	33	elderly	elderly	JJ
cord-016903-z2vqfq98	16	34	persons	person	NNS
cord-016903-z2vqfq98	16	35	.	.	.
cord-016903-z2vqfq98	17	1	In	in	IN
cord-016903-z2vqfq98	17	2	developed	develop	VBN
cord-016903-z2vqfq98	17	3	countries	country	NNS
cord-016903-z2vqfq98	17	4	like	like	IN
cord-016903-z2vqfq98	17	5	the	the	DT
cord-016903-z2vqfq98	17	6	United	United	NNP
cord-016903-z2vqfq98	17	7	States	States	NNP
cord-016903-z2vqfq98	17	8	,	,	,
cord-016903-z2vqfq98	17	9	pneumonia	pneumonia	NN
cord-016903-z2vqfq98	17	10	,	,	,
cord-016903-z2vqfq98	17	11	influenza	influenza	NN
cord-016903-z2vqfq98	17	12	and	and	CC
cord-016903-z2vqfq98	17	13	septicemia	septicemia	NN
cord-016903-z2vqfq98	17	14	are	be	VBP
cord-016903-z2vqfq98	17	15	ranked	rank	VBN
cord-016903-z2vqfq98	17	16	among	among	IN
cord-016903-z2vqfq98	17	17	the	the	DT
cord-016903-z2vqfq98	17	18	ten	ten	CD
cord-016903-z2vqfq98	17	19	major	major	JJ
cord-016903-z2vqfq98	17	20	causes	cause	NNS
cord-016903-z2vqfq98	17	21	ofdeaths	ofdeath	NNS
cord-016903-z2vqfq98	17	22	in	in	IN
cord-016903-z2vqfq98	17	23	people	people	NNS
cord-016903-z2vqfq98	17	24	aged	age	VBN
cord-016903-z2vqfq98	17	25	6S	6S	NNP
cord-016903-z2vqfq98	17	26	years	year	NNS
cord-016903-z2vqfq98	17	27	and	and	CC
cord-016903-z2vqfq98	17	28	older	old	JJR
cord-016903-z2vqfq98	17	29	.	.	.
cord-016903-z2vqfq98	18	1	1	1	LS
cord-016903-z2vqfq98	19	1	The	the	DT
cord-016903-z2vqfq98	19	2	reasons	reason	NNS
cord-016903-z2vqfq98	19	3	for	for	IN
cord-016903-z2vqfq98	19	4	the	the	DT
cord-016903-z2vqfq98	19	5	increased	increase	VBN
cord-016903-z2vqfq98	19	6	susceptibility	susceptibility	NN
cord-016903-z2vqfq98	19	7	to	to	IN
cord-016903-z2vqfq98	19	8	infectious	infectious	JJ
cord-016903-z2vqfq98	19	9	diseases	disease	NNS
cord-016903-z2vqfq98	19	10	include	include	VBP
cord-016903-z2vqfq98	19	11	epidemiological	epidemiological	JJ
cord-016903-z2vqfq98	19	12	elements	element	NNS
cord-016903-z2vqfq98	19	13	,	,	,
cord-016903-z2vqfq98	19	14	imrnunosenescence	imrnunosenescence	NN
cord-016903-z2vqfq98	19	15	,	,	,
cord-016903-z2vqfq98	19	16	malnutrition	malnutrition	NN
cord-016903-z2vqfq98	19	17	and	and	CC
cord-016903-z2vqfq98	19	18	age	age	NN
cord-016903-z2vqfq98	19	19	-	-	HYPH
cord-016903-z2vqfq98	19	20	dependent	dependent	JJ
cord-016903-z2vqfq98	19	21	anatomical	anatomical	JJ
cord-016903-z2vqfq98	19	22	alterations	alteration	NNS
cord-016903-z2vqfq98	19	23	.	.	.
cord-016903-z2vqfq98	20	1	Infectious	infectious	JJ
cord-016903-z2vqfq98	20	2	diseases	disease	NNS
cord-016903-z2vqfq98	20	3	still	still	RB
cord-016903-z2vqfq98	20	4	represent	represent	VBP
cord-016903-z2vqfq98	20	5	a	a	DT
cord-016903-z2vqfq98	20	6	major	major	JJ
cord-016903-z2vqfq98	20	7	challenge	challenge	NN
cord-016903-z2vqfq98	20	8	to	to	IN
cord-016903-z2vqfq98	20	9	human	human	JJ
cord-016903-z2vqfq98	20	10	progress	progress	NN
cord-016903-z2vqfq98	20	11	and	and	CC
cord-016903-z2vqfq98	20	12	survival	survival	NN
cord-016903-z2vqfq98	20	13	as	as	IN
cord-016903-z2vqfq98	20	14	they	-PRON-	PRP
cord-016903-z2vqfq98	20	15	are	be	VBP
cord-016903-z2vqfq98	20	16	responsible	responsible	JJ
cord-016903-z2vqfq98	20	17	for	for	IN
cord-016903-z2vqfq98	20	18	about	about	RB
cord-016903-z2vqfq98	20	19	20	20	CD
cord-016903-z2vqfq98	20	20	%	%	NN
cord-016903-z2vqfq98	20	21	ofall	ofall	NN
cord-016903-z2vqfq98	20	22	deaths	death	NNS
cord-016903-z2vqfq98	20	23	in	in	IN
cord-016903-z2vqfq98	20	24	the	the	DT
cord-016903-z2vqfq98	20	25	world	world	NN
cord-016903-z2vqfq98	20	26	.	.	.
cord-016903-z2vqfq98	21	1	This	this	DT
cord-016903-z2vqfq98	21	2	is	be	VBZ
cord-016903-z2vqfq98	21	3	not	not	RB
cord-016903-z2vqfq98	21	4	only	only	RB
cord-016903-z2vqfq98	21	5	related	relate	VBN
cord-016903-z2vqfq98	21	6	to	to	IN
cord-016903-z2vqfq98	21	7	microbial	microbial	JJ
cord-016903-z2vqfq98	21	8	and	and	CC
cord-016903-z2vqfq98	21	9	viral	viral	JJ
cord-016903-z2vqfq98	21	10	factors	factor	NNS
cord-016903-z2vqfq98	21	11	but	but	CC
cord-016903-z2vqfq98	21	12	also	also	RB
cord-016903-z2vqfq98	21	13	to	to	IN
cord-016903-z2vqfq98	21	14	social	social	JJ
cord-016903-z2vqfq98	21	15	and	and	CC
cord-016903-z2vqfq98	21	16	environmental	environmental	JJ
cord-016903-z2vqfq98	21	17	determinants	determinant	NNS
cord-016903-z2vqfq98	21	18	,	,	,
cord-016903-z2vqfq98	21	19	such	such	JJ
cord-016903-z2vqfq98	21	20	as	as	IN
cord-016903-z2vqfq98	21	21	social	social	JJ
cord-016903-z2vqfq98	21	22	upheaval	upheaval	NN
cord-016903-z2vqfq98	21	23	,	,	,
cord-016903-z2vqfq98	21	24	urbanization	urbanization	NN
cord-016903-z2vqfq98	21	25	,	,	,
cord-016903-z2vqfq98	21	26	air	air	NN
cord-016903-z2vqfq98	21	27	travel	travel	NN
cord-016903-z2vqfq98	21	28	,	,	,
cord-016903-z2vqfq98	21	29	natural	natural	JJ
cord-016903-z2vqfq98	21	30	disasters	disaster	NNS
cord-016903-z2vqfq98	21	31	and	and	CC
cord-016903-z2vqfq98	21	32	climate	climate	NN
cord-016903-z2vqfq98	21	33	change	change	NN
cord-016903-z2vqfq98	21	34	.	.	.
cord-016903-z2vqfq98	21	35	'	'	''
cord-016903-z2vqfq98	22	1	Newly	newly	RB
cord-016903-z2vqfq98	22	2	emerging	emerge	VBG
cord-016903-z2vqfq98	22	3	infectious	infectious	JJ
cord-016903-z2vqfq98	22	4	diseases	disease	NNS
cord-016903-z2vqfq98	22	5	include	include	VBP
cord-016903-z2vqfq98	22	6	acquired	acquire	VBN
cord-016903-z2vqfq98	22	7	immune	immune	JJ
cord-016903-z2vqfq98	22	8	deficiency	deficiency	NN
cord-016903-z2vqfq98	22	9	syndrome	syndrome	NN
cord-016903-z2vqfq98	22	10	(	(	-LRB-
cord-016903-z2vqfq98	22	11	AIDS	AIDS	NNP
cord-016903-z2vqfq98	22	12	)	)	-RRB-
cord-016903-z2vqfq98	22	13	,	,	,
cord-016903-z2vqfq98	22	14	hepatitis	hepatitis	NNP
cord-016903-z2vqfq98	22	15	C	C	NNP
cord-016903-z2vqfq98	22	16	,	,	,
cord-016903-z2vqfq98	22	17	several	several	JJ
cord-016903-z2vqfq98	22	18	hemorrhagic	hemorrhagic	JJ
cord-016903-z2vqfq98	22	19	fevers	fever	NNS
cord-016903-z2vqfq98	22	20	,	,	,
cord-016903-z2vqfq98	22	21	severe	severe	JJ
cord-016903-z2vqfq98	22	22	acute	acute	JJ
cord-016903-z2vqfq98	22	23	respiratory	respiratory	JJ
cord-016903-z2vqfq98	22	24	syndrome	syndrome	NN
cord-016903-z2vqfq98	22	25	(	(	-LRB-
cord-016903-z2vqfq98	22	26	SARS	SARS	NNP
cord-016903-z2vqfq98	22	27	)	)	-RRB-
cord-016903-z2vqfq98	22	28	and	and	CC
cord-016903-z2vqfq98	22	29	avian	avian	JJ
cord-016903-z2vqfq98	22	30	influenza	influenza	NN
cord-016903-z2vqfq98	22	31	.	.	.
cord-016903-z2vqfq98	23	1	The	the	DT
cord-016903-z2vqfq98	23	2	resurgence	resurgence	NN
cord-016903-z2vqfq98	23	3	ofseveral	ofseveral	JJ
cord-016903-z2vqfq98	23	4	other	other	JJ
cord-016903-z2vqfq98	23	5	infectious	infectious	JJ
cord-016903-z2vqfq98	23	6	diseases	disease	NNS
cord-016903-z2vqfq98	23	7	is	be	VBZ
cord-016903-z2vqfq98	23	8	supported	support	VBN
cord-016903-z2vqfq98	23	9	by	by	IN
cord-016903-z2vqfq98	23	10	the	the	DT
cord-016903-z2vqfq98	23	11	increased	increase	VBN
cord-016903-z2vqfq98	23	12	occurrence	occurrence	NN
cord-016903-z2vqfq98	23	13	ofmultiple	ofmultiple	JJ
cord-016903-z2vqfq98	23	14	drug	drug	NN
cord-016903-z2vqfq98	23	15	-	-	HYPH
cord-016903-z2vqfq98	23	16	resistant	resistant	JJ
cord-016903-z2vqfq98	23	17	microorganisms	microorganism	NNS
cord-016903-z2vqfq98	23	18	such	such	JJ
cord-016903-z2vqfq98	23	19	as	as	IN
cord-016903-z2vqfq98	23	20	Staphylococcus	Staphylococcus	NNP
cord-016903-z2vqfq98	23	21	aureus	aureus	NN
cord-016903-z2vqfq98	23	22	,	,	,
cord-016903-z2vqfq98	23	23	Mycobacterium	Mycobacterium	NNP
cord-016903-z2vqfq98	23	24	tuberculosis	tuberculosis	NN
cord-016903-z2vqfq98	23	25	,	,	,
cord-016903-z2vqfq98	23	26	Escherichia	escherichia	NN
cord-016903-z2vqfq98	23	27	coli	coli	NNS
cord-016903-z2vqfq98	23	28	and	and	CC
cord-016903-z2vqfq98	23	29	Streptococcuspneumoniae	Streptococcuspneumoniae	NNP
cord-016903-z2vqfq98	23	30	.	.	.
cord-016903-z2vqfq98	24	1	*	*	NFP
cord-016903-z2vqfq98	24	2	Corresponding	correspond	VBG
cord-016903-z2vqfq98	24	3	Author	author	NN
cord-016903-z2vqfq98	24	4	:	:	:
cord-016903-z2vqfq98	24	5	Beatrix	Beatrix	NNP
cord-016903-z2vqfq98	24	6	Grubeck	Grubeck	NNP
cord-016903-z2vqfq98	24	7	-	-	HYPH
cord-016903-z2vqfq98	24	8	Loebenstein	Loebenstein	NNP
cord-016903-z2vqfq98	24	9	-	-	HYPH
cord-016903-z2vqfq98	24	10	Institute	Institute	NNP
cord-016903-z2vqfq98	24	11	for	for	IN
cord-016903-z2vqfq98	24	12	Biomedical	Biomedical	NNP
cord-016903-z2vqfq98	24	13	Aging	Aging	NNP
cord-016903-z2vqfq98	24	14	Research	Research	NNP
cord-016903-z2vqfq98	24	15	,	,	,
cord-016903-z2vqfq98	24	16	Austrian	Austrian	NNP
cord-016903-z2vqfq98	24	17	Academy	Academy	NNP
cord-016903-z2vqfq98	24	18	of	of	IN
cord-016903-z2vqfq98	24	19	Sciences	Sciences	NNPS
cord-016903-z2vqfq98	24	20	,	,	,
cord-016903-z2vqfq98	24	21	Rennweg	Rennweg	NNP
cord-016903-z2vqfq98	24	22	10	10	CD
cord-016903-z2vqfq98	24	23	,	,	,
cord-016903-z2vqfq98	24	24	6020	6020	CD
cord-016903-z2vqfq98	24	25	Innsbruck	Innsbruck	NNP
cord-016903-z2vqfq98	24	26	,	,	,
cord-016903-z2vqfq98	24	27	Austria	Austria	NNP
cord-016903-z2vqfq98	24	28	.	.	.
cord-016903-z2vqfq98	25	1	Email	email	NN
cord-016903-z2vqfq98	25	2	:	:	:
cord-016903-z2vqfq98	25	3	beatrix.grubeck-loebenstein@oeaw.ac.at	beatrix.grubeck-loebenstein@oeaw.ac.at	NN
cord-016903-z2vqfq98	25	4	Immunosenescence	Immunosenescence	NNP
cord-016903-z2vqfq98	25	5	,	,	,
cord-016903-z2vqfq98	25	6	edited	edit	VBN
cord-016903-z2vqfq98	25	7	by	by	IN
cord-016903-z2vqfq98	25	8	Graham	Graham	NNP
cord-016903-z2vqfq98	25	9	Pawelec	Pawelec	NNP
cord-016903-z2vqfq98	25	10	.	.	.
cord-016903-z2vqfq98	26	1	©	©	NN
cord-016903-z2vqfq98	26	2	2007	2007	CD
cord-016903-z2vqfq98	27	1	Landes	Landes	NNP
cord-016903-z2vqfq98	27	2	Bioscience	Bioscience	NNP
cord-016903-z2vqfq98	27	3	and	and	CC
cord-016903-z2vqfq98	27	4	Springer	Springer	NNP
cord-016903-z2vqfq98	27	5	Science+Business	Science+Business	NNP
cord-016903-z2vqfq98	27	6	Media	Media	NNP
cord-016903-z2vqfq98	27	7	.	.	.
cord-016903-z2vqfq98	28	1	Altogether	altogether	RB
cord-016903-z2vqfq98	28	2	,	,	,
cord-016903-z2vqfq98	28	3	this	this	DT
cord-016903-z2vqfq98	28	4	represents	represent	VBZ
cord-016903-z2vqfq98	28	5	an	an	DT
cord-016903-z2vqfq98	28	6	enormous	enormous	JJ
cord-016903-z2vqfq98	28	7	economic	economic	JJ
cord-016903-z2vqfq98	28	8	burden	burden	NN
cord-016903-z2vqfq98	28	9	on	on	IN
cord-016903-z2vqfq98	28	10	health	health	NN
cord-016903-z2vqfq98	28	11	care	care	NN
cord-016903-z2vqfq98	28	12	systems	system	NNS
cord-016903-z2vqfq98	28	13	all	all	RB
cord-016903-z2vqfq98	28	14	over	over	IN
cord-016903-z2vqfq98	28	15	the	the	DT
cord-016903-z2vqfq98	28	16	world	world	NN
cord-016903-z2vqfq98	28	17	.	.	.
cord-016903-z2vqfq98	29	1	For	for	IN
cord-016903-z2vqfq98	29	2	instance	instance	NN
cord-016903-z2vqfq98	29	3	,	,	,
cord-016903-z2vqfq98	29	4	the	the	DT
cord-016903-z2vqfq98	29	5	annual	annual	JJ
cord-016903-z2vqfq98	29	6	costs	cost	NNS
cord-016903-z2vqfq98	29	7	ofmedical	ofmedical	JJ
cord-016903-z2vqfq98	29	8	care	care	NN
cord-016903-z2vqfq98	29	9	for	for	IN
cord-016903-z2vqfq98	29	10	treating	treat	VBG
cord-016903-z2vqfq98	29	11	infectious	infectious	JJ
cord-016903-z2vqfq98	29	12	diseases	disease	NNS
cord-016903-z2vqfq98	29	13	in	in	IN
cord-016903-z2vqfq98	29	14	the	the	DT
cord-016903-z2vqfq98	29	15	United	United	NNP
cord-016903-z2vqfq98	29	16	States	States	NNP
cord-016903-z2vqfq98	29	17	alone	alone	RB
cord-016903-z2vqfq98	29	18	is	be	VBZ
cord-016903-z2vqfq98	29	19	about	about	IN
cord-016903-z2vqfq98	29	20	$	$	$
cord-016903-z2vqfq98	29	21	120	120	CD
cord-016903-z2vqfq98	29	22	billion	billion	CD
cord-016903-z2vqfq98	29	23	and	and	CC
cord-016903-z2vqfq98	29	24	for	for	IN
cord-016903-z2vqfq98	29	25	treating	treat	VBG
cord-016903-z2vqfq98	29	26	antimicrobial	antimicrobial	JJ
cord-016903-z2vqfq98	29	27	-	-	HYPH
cord-016903-z2vqfq98	29	28	resistant	resistant	JJ
cord-016903-z2vqfq98	29	29	infections	infection	NNS
cord-016903-z2vqfq98	29	30	it	-PRON-	PRP
cord-016903-z2vqfq98	29	31	may	may	MD
cord-016903-z2vqfq98	29	32	be	be	VB
cord-016903-z2vqfq98	29	33	as	as	RB
cord-016903-z2vqfq98	29	34	high	high	JJ
cord-016903-z2vqfq98	29	35	as	as	IN
cord-016903-z2vqfq98	29	36	$	$	$
cord-016903-z2vqfq98	29	37	5	5	CD
cord-016903-z2vqfq98	29	38	billion	billion	CD
cord-016903-z2vqfq98	29	39	.	.	.
cord-016903-z2vqfq98	29	40	'	'	''
cord-016903-z2vqfq98	30	1	A	a	DT
cord-016903-z2vqfq98	30	2	great	great	JJ
cord-016903-z2vqfq98	30	3	success	success	NN
cord-016903-z2vqfq98	30	4	story	story	NN
cord-016903-z2vqfq98	30	5	was	be	VBD
cord-016903-z2vqfq98	30	6	the	the	DT
cord-016903-z2vqfq98	30	7	implementation	implementation	NN
cord-016903-z2vqfq98	30	8	oflarge	oflarge	JJ
cord-016903-z2vqfq98	30	9	-	-	HYPH
cord-016903-z2vqfq98	30	10	scale	scale	NN
cord-016903-z2vqfq98	30	11	vaccination	vaccination	NN
cord-016903-z2vqfq98	30	12	strategies	strategy	NNS
cord-016903-z2vqfq98	30	13	that	that	WDT
cord-016903-z2vqfq98	30	14	led	lead	VBD
cord-016903-z2vqfq98	30	15	to	to	IN
cord-016903-z2vqfq98	30	16	the	the	DT
cord-016903-z2vqfq98	30	17	eradication	eradication	NN
cord-016903-z2vqfq98	30	18	of	of	IN
cord-016903-z2vqfq98	30	19	smallpox	smallpox	NN
cord-016903-z2vqfq98	30	20	in	in	IN
cord-016903-z2vqfq98	30	21	1980	1980	CD
cord-016903-z2vqfq98	30	22	4	4	CD
cord-016903-z2vqfq98	30	23	and	and	CC
cord-016903-z2vqfq98	30	24	to	to	IN
cord-016903-z2vqfq98	30	25	a	a	DT
cord-016903-z2vqfq98	30	26	drastic	drastic	JJ
cord-016903-z2vqfq98	30	27	reduction	reduction	NN
cord-016903-z2vqfq98	30	28	ofpoliomyelitis	ofpoliomyelitis	NN
cord-016903-z2vqfq98	30	29	,	,	,
cord-016903-z2vqfq98	30	30	tetanus	tetanus	NN
cord-016903-z2vqfq98	30	31	,	,	,
cord-016903-z2vqfq98	30	32	diphtheria	diphtheria	NN
cord-016903-z2vqfq98	30	33	,	,	,
cord-016903-z2vqfq98	30	34	measles	measle	NNS
cord-016903-z2vqfq98	30	35	,	,	,
cord-016903-z2vqfq98	30	36	pertussis	pertussis	NN
cord-016903-z2vqfq98	30	37	and	and	CC
cord-016903-z2vqfq98	30	38	meningitis	meningitis	NN
cord-016903-z2vqfq98	30	39	.	.	.
cord-016903-z2vqfq98	31	1	Presently	presently	RB
cord-016903-z2vqfq98	31	2	,	,	,
cord-016903-z2vqfq98	31	3	vaccinations	vaccination	NNS
cord-016903-z2vqfq98	31	4	are	be	VBP
cord-016903-z2vqfq98	31	5	still	still	RB
cord-016903-z2vqfq98	31	6	considered	consider	VBN
cord-016903-z2vqfq98	31	7	the	the	DT
cord-016903-z2vqfq98	31	8	most	most	RBS
cord-016903-z2vqfq98	31	9	cost	cost	NN
cord-016903-z2vqfq98	31	10	-	-	HYPH
cord-016903-z2vqfq98	31	11	effective	effective	JJ
cord-016903-z2vqfq98	31	12	medical	medical	JJ
cord-016903-z2vqfq98	31	13	procedure	procedure	NN
cord-016903-z2vqfq98	31	14	for	for	IN
cord-016903-z2vqfq98	31	15	preventingmorbidity	preventingmorbidity	NN
cord-016903-z2vqfq98	31	16	and	and	CC
cord-016903-z2vqfq98	31	17	mortality	mortality	NN
cord-016903-z2vqfq98	31	18	caused	cause	VBN
cord-016903-z2vqfq98	31	19	by	by	IN
cord-016903-z2vqfq98	31	20	infectious	infectious	JJ
cord-016903-z2vqfq98	31	21	diseases	disease	NNS
cord-016903-z2vqfq98	31	22	.	.	.
cord-016903-z2vqfq98	32	1	26	26	CD
cord-016903-z2vqfq98	32	2	different	different	JJ
cord-016903-z2vqfq98	32	3	infectious	infectious	JJ
cord-016903-z2vqfq98	32	4	diseases	disease	NNS
cord-016903-z2vqfq98	32	5	can	can	MD
cord-016903-z2vqfq98	32	6	be	be	VB
cord-016903-z2vqfq98	32	7	prevented	prevent	VBN
cord-016903-z2vqfq98	32	8	by	by	IN
cord-016903-z2vqfq98	32	9	vaccinations	vaccination	NNS
cord-016903-z2vqfq98	32	10	and	and	CC
cord-016903-z2vqfq98	32	11	61	61	CD
cord-016903-z2vqfq98	32	12	vaccines	vaccine	NNS
cord-016903-z2vqfq98	32	13	are	be	VBP
cord-016903-z2vqfq98	32	14	being	be	VBG
cord-016903-z2vqfq98	32	15	developed	develop	VBN
cord-016903-z2vqfq98	32	16	according	accord	VBG
cord-016903-z2vqfq98	32	17	to	to	IN
cord-016903-z2vqfq98	32	18	a	a	DT
cord-016903-z2vqfq98	32	19	2004	2004	CD
cord-016903-z2vqfq98	32	20	survey	survey	NN
cord-016903-z2vqfq98	32	21	by	by	IN
cord-016903-z2vqfq98	32	22	the	the	DT
cord-016903-z2vqfq98	32	23	Pharmaceutical	Pharmaceutical	NNP
cord-016903-z2vqfq98	32	24	Research	Research	NNP
cord-016903-z2vqfq98	32	25	and	and	CC
cord-016903-z2vqfq98	32	26	Manufacturers	Manufacturers	NNPS
cord-016903-z2vqfq98	32	27	ofAmerica	ofAmerica	NNP
cord-016903-z2vqfq98	32	28	,	,	,
cord-016903-z2vqfq98	32	29	"	"	``
cord-016903-z2vqfq98	32	30	The	the	DT
cord-016903-z2vqfq98	32	31	new	new	JJ
cord-016903-z2vqfq98	32	32	candidate	candidate	NN
cord-016903-z2vqfq98	32	33	vaccines	vaccine	NNS
cord-016903-z2vqfq98	32	34	are	be	VBP
cord-016903-z2vqfq98	32	35	intended	intend	VBN
cord-016903-z2vqfq98	32	36	to	to	TO
cord-016903-z2vqfq98	32	37	provide	provide	VB
cord-016903-z2vqfq98	32	38	protection	protection	NN
cord-016903-z2vqfq98	32	39	against	against	IN
cord-016903-z2vqfq98	32	40	diseases	disease	NNS
cord-016903-z2vqfq98	32	41	caused	cause	VBN
cord-016903-z2vqfq98	32	42	by	by	IN
cord-016903-z2vqfq98	32	43	rotavirus	rotavirus	NN
cord-016903-z2vqfq98	32	44	,	,	,
cord-016903-z2vqfq98	32	45	herpes	herpes	NN
cord-016903-z2vqfq98	32	46	zoster	zoster	NN
cord-016903-z2vqfq98	32	47	and	and	CC
cord-016903-z2vqfq98	32	48	papilloma	papilloma	NN
cord-016903-z2vqfq98	32	49	virus	virus	NN
cord-016903-z2vqfq98	32	50	and	and	CC
cord-016903-z2vqfq98	32	51	will	will	MD
cord-016903-z2vqfq98	32	52	be	be	VB
cord-016903-z2vqfq98	32	53	available	available	JJ
cord-016903-z2vqfq98	32	54	from	from	IN
cord-016903-z2vqfq98	32	55	2007	2007	CD
cord-016903-z2vqfq98	32	56	onwards	onwards	RB
cord-016903-z2vqfq98	32	57	(	(	-LRB-
cord-016903-z2vqfq98	32	58	Table	table	NN
cord-016903-z2vqfq98	32	59	1	1	CD
cord-016903-z2vqfq98	32	60	)	)	-RRB-
cord-016903-z2vqfq98	32	61	.	.	.
cord-016903-z2vqfq98	33	1	But	but	CC
cord-016903-z2vqfq98	33	2	also	also	RB
cord-016903-z2vqfq98	33	3	improved	improve	VBD
cord-016903-z2vqfq98	33	4	vaccines	vaccine	NNS
cord-016903-z2vqfq98	33	5	against	against	IN
cord-016903-z2vqfq98	33	6	influenza	influenza	NN
cord-016903-z2vqfq98	33	7	,	,	,
cord-016903-z2vqfq98	33	8	pneumonia	pneumonia	NN
cord-016903-z2vqfq98	33	9	and	and	CC
cord-016903-z2vqfq98	33	10	tuberculosis	tuberculosis	NN
cord-016903-z2vqfq98	33	11	are	be	VBP
cord-016903-z2vqfq98	33	12	currently	currently	RB
cord-016903-z2vqfq98	33	13	being	be	VBG
cord-016903-z2vqfq98	33	14	tested	test	VBN
cord-016903-z2vqfq98	33	15	in	in	IN
cord-016903-z2vqfq98	33	16	clinical	clinical	JJ
cord-016903-z2vqfq98	33	17	trials	trial	NNS
cord-016903-z2vqfq98	33	18	(	(	-LRB-
cord-016903-z2vqfq98	33	19	Table	table	NN
cord-016903-z2vqfq98	33	20	1	1	CD
cord-016903-z2vqfq98	33	21	)	)	-RRB-
cord-016903-z2vqfq98	33	22	.	.	.
cord-016903-z2vqfq98	34	1	This	this	DT
cord-016903-z2vqfq98	34	2	chapter	chapter	NN
cord-016903-z2vqfq98	34	3	now	now	RB
cord-016903-z2vqfq98	34	4	outlines	outline	VBZ
cord-016903-z2vqfq98	34	5	the	the	DT
cord-016903-z2vqfq98	34	6	relevance	relevance	NN
cord-016903-z2vqfq98	34	7	ofvaccines	ofvaccines	NNP
cord-016903-z2vqfq98	34	8	to	to	TO
cord-016903-z2vqfq98	34	9	fight	fight	VB
cord-016903-z2vqfq98	34	10	infectious	infectious	JJ
cord-016903-z2vqfq98	34	11	diseases	disease	NNS
cord-016903-z2vqfq98	34	12	in	in	IN
cord-016903-z2vqfq98	34	13	old	old	JJ
cord-016903-z2vqfq98	34	14	age	age	NN
cord-016903-z2vqfq98	34	15	and	and	CC
cord-016903-z2vqfq98	34	16	how	how	WRB
cord-016903-z2vqfq98	34	17	age	age	NN
cord-016903-z2vqfq98	34	18	-	-	HYPH
cord-016903-z2vqfq98	34	19	related	relate	VBN
cord-016903-z2vqfq98	34	20	changes	change	NNS
cord-016903-z2vqfq98	34	21	within	within	IN
cord-016903-z2vqfq98	34	22	the	the	DT
cord-016903-z2vqfq98	34	23	immune	immune	JJ
cord-016903-z2vqfq98	34	24	system	system	NN
cord-016903-z2vqfq98	34	25	contribute	contribute	VBP
cord-016903-z2vqfq98	34	26	to	to	IN
cord-016903-z2vqfq98	34	27	the	the	DT
cord-016903-z2vqfq98	34	28	decreased	decrease	VBN
cord-016903-z2vqfq98	34	29	efficacy	efficacy	NN
cord-016903-z2vqfq98	34	30	of	of	IN
cord-016903-z2vqfq98	34	31	vaccines	vaccine	NNS
cord-016903-z2vqfq98	34	32	.	.	.
cord-016903-z2vqfq98	35	1	It	-PRON-	PRP
cord-016903-z2vqfq98	35	2	also	also	RB
cord-016903-z2vqfq98	35	3	discusses	discuss	VBZ
cord-016903-z2vqfq98	35	4	the	the	DT
cord-016903-z2vqfq98	35	5	progress	progress	NN
cord-016903-z2vqfq98	35	6	made	make	VBN
cord-016903-z2vqfq98	35	7	in	in	IN
cord-016903-z2vqfq98	35	8	the	the	DT
cord-016903-z2vqfq98	35	9	development	development	NN
cord-016903-z2vqfq98	35	10	of	of	IN
cord-016903-z2vqfq98	35	11	vaccines	vaccine	NNS
cord-016903-z2vqfq98	35	12	with	with	IN
cord-016903-z2vqfq98	35	13	improved	improve	VBN
cord-016903-z2vqfq98	35	14	immunogenicity	immunogenicity	NN
cord-016903-z2vqfq98	35	15	in	in	IN
cord-016903-z2vqfq98	35	16	elderly	elderly	JJ
cord-016903-z2vqfq98	35	17	persons	person	NNS
cord-016903-z2vqfq98	35	18	.	.	.
cord-016903-z2vqfq98	36	1	Outbreaks	outbreak	NNS
cord-016903-z2vqfq98	36	2	of	of	IN
cord-016903-z2vqfq98	36	3	deadly	deadly	JJ
cord-016903-z2vqfq98	36	4	infectious	infectious	JJ
cord-016903-z2vqfq98	36	5	diseases	disease	NNS
cord-016903-z2vqfq98	36	6	such	such	JJ
cord-016903-z2vqfq98	36	7	as	as	IN
cord-016903-z2vqfq98	36	8	Ebola	Ebola	NNP
cord-016903-z2vqfq98	36	9	,	,	,
cord-016903-z2vqfq98	36	10	Marburg	Marburg	NNP
cord-016903-z2vqfq98	36	11	,	,	,
cord-016903-z2vqfq98	36	12	SARS	SARS	NNP
cord-016903-z2vqfq98	36	13	or	or	CC
cord-016903-z2vqfq98	36	14	the	the	DT
cord-016903-z2vqfq98	36	15	H5Nl	H5Nl	NNP
cord-016903-z2vqfq98	36	16	avian	avian	JJ
cord-016903-z2vqfq98	36	17	influenza	influenza	NN
cord-016903-z2vqfq98	36	18	regularly	regularly	RB
cord-016903-z2vqfq98	36	19	alert	alert	VBP
cord-016903-z2vqfq98	36	20	the	the	DT
cord-016903-z2vqfq98	36	21	world	world	NN
cord-016903-z2vqfq98	36	22	,	,	,
cord-016903-z2vqfq98	36	23	whereas	whereas	IN
cord-016903-z2vqfq98	36	24	there	there	EX
cord-016903-z2vqfq98	36	25	is	be	VBZ
cord-016903-z2vqfq98	36	26	not	not	RB
cord-016903-z2vqfq98	36	27	much	much	JJ
cord-016903-z2vqfq98	36	28	public	public	JJ
cord-016903-z2vqfq98	36	29	attention	attention	NN
cord-016903-z2vqfq98	36	30	paid	pay	VBN
cord-016903-z2vqfq98	36	31	to	to	IN
cord-016903-z2vqfq98	36	32	infectious	infectious	JJ
cord-016903-z2vqfq98	36	33	diseases	disease	NNS
cord-016903-z2vqfq98	36	34	that	that	WDT
cord-016903-z2vqfq98	36	35	cause	cause	VBP
cord-016903-z2vqfq98	36	36	substantial	substantial	JJ
cord-016903-z2vqfq98	36	37	morbidity	morbidity	NN
cord-016903-z2vqfq98	36	38	and	and	CC
cord-016903-z2vqfq98	36	39	mortality	mortality	NN
cord-016903-z2vqfq98	36	40	among	among	IN
cord-016903-z2vqfq98	36	41	the	the	DT
cord-016903-z2vqfq98	36	42	elderly	elderly	JJ
cord-016903-z2vqfq98	36	43	population	population	NN
cord-016903-z2vqfq98	36	44	.	.	.
cord-016903-z2vqfq98	37	1	For	for	IN
cord-016903-z2vqfq98	37	2	instance	instance	NN
cord-016903-z2vqfq98	37	3	,	,	,
cord-016903-z2vqfq98	37	4	influenza	influenza	NN
cord-016903-z2vqfq98	37	5	,	,	,
cord-016903-z2vqfq98	37	6	invasive	invasive	JJ
cord-016903-z2vqfq98	37	7	Streptococcus	streptococcus	NN
cord-016903-z2vqfq98	37	8	pneumoniae	pneumoniae	NN
cord-016903-z2vqfq98	37	9	infection	infection	NN
cord-016903-z2vqfq98	37	10	,	,	,
cord-016903-z2vqfq98	37	11	urinary	urinary	JJ
cord-016903-z2vqfq98	37	12	tract	tract	NN
cord-016903-z2vqfq98	37	13	and	and	CC
cord-016903-z2vqfq98	37	14	skin	skin	NN
cord-016903-z2vqfq98	37	15	infections	infection	NNS
cord-016903-z2vqfq98	37	16	have	have	VBP
cord-016903-z2vqfq98	37	17	a	a	DT
cord-016903-z2vqfq98	37	18	higher	high	JJR
cord-016903-z2vqfq98	37	19	prevalence	prevalence	NN
cord-016903-z2vqfq98	37	20	in	in	IN
cord-016903-z2vqfq98	37	21	elderly	elderly	JJ
cord-016903-z2vqfq98	37	22	persons	person	NNS
cord-016903-z2vqfq98	37	23	,	,	,
cord-016903-z2vqfq98	37	24	"	"	``
cord-016903-z2vqfq98	37	25	Old	old	JJ
cord-016903-z2vqfq98	37	26	individuals	individual	NNS
cord-016903-z2vqfq98	37	27	may	may	MD
cord-016903-z2vqfq98	37	28	also	also	RB
cord-016903-z2vqfq98	37	29	fail	fail	VB
cord-016903-z2vqfq98	37	30	to	to	TO
cord-016903-z2vqfq98	37	31	respond	respond	VB
cord-016903-z2vqfq98	37	32	sufficiently	sufficiently	RB
cord-016903-z2vqfq98	37	33	to	to	IN
cord-016903-z2vqfq98	37	34	therapy	therapy	NN
cord-016903-z2vqfq98	37	35	and	and	CC
cord-016903-z2vqfq98	37	36	frequently	frequently	RB
cord-016903-z2vqfq98	37	37	suffer	suffer	VB
cord-016903-z2vqfq98	37	38	from	from	IN
cord-016903-z2vqfq98	37	39	opportunistic	opportunistic	JJ
cord-016903-z2vqfq98	37	40	infections	infection	NNS
cord-016903-z2vqfq98	37	41	,	,	,
cord-016903-z2vqfq98	37	42	recurrent	recurrent	JJ
cord-016903-z2vqfq98	37	43	infections	infection	NNS
cord-016903-z2vqfq98	37	44	with	with	IN
cord-016903-z2vqfq98	37	45	the	the	DT
cord-016903-z2vqfq98	37	46	same	same	JJ
cord-016903-z2vqfq98	37	47	pathogen	pathogen	NN
cord-016903-z2vqfq98	37	48	or	or	CC
cord-016903-z2vqfq98	37	49	reactivation	reactivation	NN
cord-016903-z2vqfq98	37	50	oflatent	oflatent	JJ
cord-016903-z2vqfq98	37	51	diseases	disease	NNS
cord-016903-z2vqfq98	37	52	,	,	,
cord-016903-z2vqfq98	37	53	such	such	JJ
cord-016903-z2vqfq98	37	54	as	as	IN
cord-016903-z2vqfq98	37	55	those	those	DT
cord-016903-z2vqfq98	37	56	caused	cause	VBN
cord-016903-z2vqfq98	37	57	by	by	IN
cord-016903-z2vqfq98	37	58	Mycobacterium	Mycobacterium	NNP
cord-016903-z2vqfq98	37	59	tuberculosis	tuberculosis	NN
cord-016903-z2vqfq98	37	60	or	or	CC
cord-016903-z2vqfq98	37	61	the	the	DT
cord-016903-z2vqfq98	37	62	Varicella	Varicella	NNP
cord-016903-z2vqfq98	37	63	zoster	zoster	NNP
cord-016903-z2vqfq98	37	64	virus	virus	NN
cord-016903-z2vqfq98	37	65	.	.	.
cord-016903-z2vqfq98	38	1	There	there	EX
cord-016903-z2vqfq98	38	2	are	be	VBP
cord-016903-z2vqfq98	38	3	no	no	DT
cord-016903-z2vqfq98	38	4	vaccines	vaccine	NNS
cord-016903-z2vqfq98	38	5	available	available	JJ
cord-016903-z2vqfq98	38	6	for	for	IN
cord-016903-z2vqfq98	38	7	many	many	JJ
cord-016903-z2vqfq98	38	8	infectious	infectious	JJ
cord-016903-z2vqfq98	38	9	pathogens	pathogen	NNS
cord-016903-z2vqfq98	38	10	that	that	WDT
cord-016903-z2vqfq98	38	11	are	be	VBP
cord-016903-z2vqfq98	38	12	frequent	frequent	JJ
cord-016903-z2vqfq98	38	13	in	in	IN
cord-016903-z2vqfq98	38	14	elderly	elderly	JJ
cord-016903-z2vqfq98	38	15	subjects	subject	NNS
cord-016903-z2vqfq98	38	16	and	and	CC
cord-016903-z2vqfq98	38	17	existing	exist	VBG
cord-016903-z2vqfq98	38	18	vaccines	vaccine	NNS
cord-016903-z2vqfq98	38	19	are	be	VBP
cord-016903-z2vqfq98	38	20	underused	underused	JJ
cord-016903-z2vqfq98	38	21	and	and	CC
cord-016903-z2vqfq98	38	22	often	often	RB
cord-016903-z2vqfq98	38	23	do	do	VBP
cord-016903-z2vqfq98	38	24	not	not	RB
cord-016903-z2vqfq98	38	25	assure	assure	VB
cord-016903-z2vqfq98	38	26	such	such	PDT
cord-016903-z2vqfq98	38	27	an	an	DT
cord-016903-z2vqfq98	38	28	effective	effective	JJ
cord-016903-z2vqfq98	38	29	protection	protection	NN
cord-016903-z2vqfq98	38	30	as	as	IN
cord-016903-z2vqfq98	38	31	in	in	IN
cord-016903-z2vqfq98	38	32	young	young	JJ
cord-016903-z2vqfq98	38	33	subjects	subject	NNS
cord-016903-z2vqfq98	38	34	.	.	.
cord-016903-z2vqfq98	39	1	The	the	DT
cord-016903-z2vqfq98	39	2	following	following	JJ
cord-016903-z2vqfq98	39	3	paragraphs	paragraph	NNS
cord-016903-z2vqfq98	39	4	will	will	MD
cord-016903-z2vqfq98	39	5	highlight	highlight	VB
cord-016903-z2vqfq98	39	6	the	the	DT
cord-016903-z2vqfq98	39	7	most	most	RBS
cord-016903-z2vqfq98	39	8	important	important	JJ
cord-016903-z2vqfq98	39	9	infectious	infectious	JJ
cord-016903-z2vqfq98	39	10	diseases	disease	NNS
cord-016903-z2vqfq98	39	11	which	which	WDT
cord-016903-z2vqfq98	39	12	threaten	threaten	VBP
cord-016903-z2vqfq98	39	13	the	the	DT
cord-016903-z2vqfq98	39	14	elderly	elderly	JJ
cord-016903-z2vqfq98	39	15	population	population	NN
cord-016903-z2vqfq98	39	16	and	and	CC
cord-016903-z2vqfq98	39	17	will	will	MD
cord-016903-z2vqfq98	39	18	provide	provide	VB
cord-016903-z2vqfq98	39	19	information	information	NN
cord-016903-z2vqfq98	39	20	on	on	IN
cord-016903-z2vqfq98	39	21	epidemiology	epidemiology	NN
cord-016903-z2vqfq98	39	22	,	,	,
cord-016903-z2vqfq98	39	23	vaccine	vaccine	NN
cord-016903-z2vqfq98	39	24	availability	availability	NN
cord-016903-z2vqfq98	39	25	and	and	CC
cord-016903-z2vqfq98	39	26	efficacy	efficacy	NN
cord-016903-z2vqfq98	39	27	,	,	,
cord-016903-z2vqfq98	39	28	vaccination	vaccination	NN
cord-016903-z2vqfq98	39	29	coverage	coverage	NN
cord-016903-z2vqfq98	39	30	and	and	CC
cord-016903-z2vqfq98	39	31	general	general	JJ
cord-016903-z2vqfq98	39	32	health	health	NN
cord-016903-z2vqfq98	39	33	authority	authority	NN
cord-016903-z2vqfq98	39	34	recommendations	recommendation	NNS
cord-016903-z2vqfq98	39	35	.	.	.
cord-016903-z2vqfq98	40	1	Influenza	influenza	NN
cord-016903-z2vqfq98	40	2	is	be	VBZ
cord-016903-z2vqfq98	40	3	a	a	DT
cord-016903-z2vqfq98	40	4	highly	highly	RB
cord-016903-z2vqfq98	40	5	contagious	contagious	JJ
cord-016903-z2vqfq98	40	6	,	,	,
cord-016903-z2vqfq98	40	7	acute	acute	JJ
cord-016903-z2vqfq98	40	8	viral	viral	JJ
cord-016903-z2vqfq98	40	9	respiratory	respiratory	JJ
cord-016903-z2vqfq98	40	10	disease	disease	NN
cord-016903-z2vqfq98	40	11	that	that	WDT
cord-016903-z2vqfq98	40	12	causes	cause	VBZ
cord-016903-z2vqfq98	40	13	significant	significant	JJ
cord-016903-z2vqfq98	40	14	morbidity	morbidity	NN
cord-016903-z2vqfq98	40	15	and	and	CC
cord-016903-z2vqfq98	40	16	mortality	mortality	NN
cord-016903-z2vqfq98	40	17	.	.	.
cord-016903-z2vqfq98	41	1	The	the	DT
cord-016903-z2vqfq98	41	2	annual	annual	JJ
cord-016903-z2vqfq98	41	3	outbreaks	outbreak	NNS
cord-016903-z2vqfq98	41	4	affect	affect	VBP
cord-016903-z2vqfq98	41	5	approximately	approximately	RB
cord-016903-z2vqfq98	41	6	5	5	CD
cord-016903-z2vqfq98	41	7	-	-	SYM
cord-016903-z2vqfq98	41	8	20	20	CD
cord-016903-z2vqfq98	41	9	%	%	NN
cord-016903-z2vqfq98	41	10	ofthe	ofthe	DT
cord-016903-z2vqfq98	41	11	population	population	NN
cord-016903-z2vqfq98	41	12	worldwide	worldwide	RB
cord-016903-z2vqfq98	41	13	with	with	IN
cord-016903-z2vqfq98	41	14	3	3	CD
cord-016903-z2vqfq98	41	15	-	-	SYM
cord-016903-z2vqfq98	41	16	5	5	CD
cord-016903-z2vqfq98	41	17	million	million	CD
cord-016903-z2vqfq98	41	18	cases	case	NNS
cord-016903-z2vqfq98	41	19	ofsevere	ofsevere	JJ
cord-016903-z2vqfq98	41	20	illness	illness	NN
cord-016903-z2vqfq98	41	21	and	and	CC
cord-016903-z2vqfq98	41	22	up	up	IN
cord-016903-z2vqfq98	41	23	to	to	IN
cord-016903-z2vqfq98	41	24	one	one	CD
cord-016903-z2vqfq98	41	25	million	million	CD
cord-016903-z2vqfq98	41	26	deaths	death	NNS
cord-016903-z2vqfq98	41	27	each	each	DT
cord-016903-z2vqfq98	41	28	year	year	NN
cord-016903-z2vqfq98	41	29	.	.	.
cord-016903-z2vqfq98	42	1	Especially	especially	RB
cord-016903-z2vqfq98	42	2	elderly	elderly	JJ
cord-016903-z2vqfq98	42	3	people	people	NNS
cord-016903-z2vqfq98	42	4	and	and	CC
cord-016903-z2vqfq98	42	5	persons	person	NNS
cord-016903-z2vqfq98	42	6	that	that	WDT
cord-016903-z2vqfq98	42	7	are	be	VBP
cord-016903-z2vqfq98	42	8	chronically	chronically	RB
cord-016903-z2vqfq98	42	9	ill	ill	JJ
cord-016903-z2vqfq98	42	10	or	or	CC
cord-016903-z2vqfq98	42	11	otherwise	otherwise	RB
cord-016903-z2vqfq98	42	12	immunocompromised	immunocompromised	JJ
cord-016903-z2vqfq98	42	13	are	be	VBP
cord-016903-z2vqfq98	42	14	at	at	IN
cord-016903-z2vqfq98	42	15	enhanced	enhanced	JJ
cord-016903-z2vqfq98	42	16	risk	risk	NN
cord-016903-z2vqfq98	42	17	.	.	.
cord-016903-z2vqfq98	43	1	For	for	IN
cord-016903-z2vqfq98	43	2	example	example	NN
cord-016903-z2vqfq98	43	3	,	,	,
cord-016903-z2vqfq98	43	4	during	during	IN
cord-016903-z2vqfq98	43	5	influenza	influenza	NN
cord-016903-z2vqfq98	43	6	epidemics	epidemic	NNS
cord-016903-z2vqfq98	43	7	,	,	,
cord-016903-z2vqfq98	43	8	Barker	Barker	NNP
cord-016903-z2vqfq98	43	9	and	and	CC
cord-016903-z2vqfq98	43	10	Mullooly	Mullooly	NNP
cord-016903-z2vqfq98	43	11	reported	report	VBD
cord-016903-z2vqfq98	43	12	two	two	CD
cord-016903-z2vqfq98	43	13	deaths	death	NNS
cord-016903-z2vqfq98	43	14	per	per	IN
cord-016903-z2vqfq98	43	15	100,000	100,000	CD
cord-016903-z2vqfq98	43	16	healthy	healthy	JJ
cord-016903-z2vqfq98	43	17	people	people	NNS
cord-016903-z2vqfq98	43	18	below	below	IN
cord-016903-z2vqfq98	43	19	65	65	CD
cord-016903-z2vqfq98	43	20	years	year	NNS
cord-016903-z2vqfq98	43	21	ofage	ofage	NN
cord-016903-z2vqfq98	43	22	compared	compare	VBN
cord-016903-z2vqfq98	43	23	with	with	IN
cord-016903-z2vqfq98	43	24	797	797	CD
cord-016903-z2vqfq98	43	25	per	per	IN
cord-016903-z2vqfq98	43	26	100,000	100,000	CD
cord-016903-z2vqfq98	43	27	in	in	IN
cord-016903-z2vqfq98	43	28	those	those	DT
cord-016903-z2vqfq98	43	29	over	over	IN
cord-016903-z2vqfq98	43	30	65	65	CD
cord-016903-z2vqfq98	43	31	with	with	IN
cord-016903-z2vqfq98	43	32	two	two	CD
cord-016903-z2vqfq98	43	33	or	or	CC
cord-016903-z2vqfq98	43	34	more	more	JJR
cord-016903-z2vqfq98	43	35	high	high	JJ
cord-016903-z2vqfq98	43	36	-	-	HYPH
cord-016903-z2vqfq98	43	37	risk	risk	NN
cord-016903-z2vqfq98	43	38	conditions	condition	NNS
cord-016903-z2vqfq98	43	39	?	?	.
cord-016903-z2vqfq98	44	1	In	in	IN
cord-016903-z2vqfq98	44	2	contrast	contrast	NN
cord-016903-z2vqfq98	44	3	to	to	IN
cord-016903-z2vqfq98	44	4	measles	measle	NNS
cord-016903-z2vqfq98	44	5	,	,	,
cord-016903-z2vqfq98	44	6	smallpox	smallpox	NN
cord-016903-z2vqfq98	44	7	and	and	CC
cord-016903-z2vqfq98	44	8	poliomyelitis	poliomyelitis	NN
cord-016903-z2vqfq98	44	9	,	,	,
cord-016903-z2vqfq98	44	10	influenza	influenza	NN
cord-016903-z2vqfq98	44	11	is	be	VBZ
cord-016903-z2vqfq98	44	12	caused	cause	VBN
cord-016903-z2vqfq98	44	13	by	by	IN
cord-016903-z2vqfq98	44	14	viruses	virus	NNS
cord-016903-z2vqfq98	44	15	that	that	WDT
cord-016903-z2vqfq98	44	16	undergo	undergo	VBP
cord-016903-z2vqfq98	44	17	continuous	continuous	JJ
cord-016903-z2vqfq98	44	18	antigenic	antigenic	JJ
cord-016903-z2vqfq98	44	19	variation	variation	NN
cord-016903-z2vqfq98	44	20	and	and	CC
cord-016903-z2vqfq98	44	21	possess	possess	VBP
cord-016903-z2vqfq98	44	22	an	an	DT
cord-016903-z2vqfq98	44	23	animal	animal	NN
cord-016903-z2vqfq98	44	24	reservoir	reservoir	NN
cord-016903-z2vqfq98	44	25	.	.	.
cord-016903-z2vqfq98	45	1	Therefore	therefore	RB
cord-016903-z2vqfq98	45	2	,	,	,
cord-016903-z2vqfq98	45	3	we	-PRON-	PRP
cord-016903-z2vqfq98	45	4	are	be	VBP
cord-016903-z2vqfq98	45	5	recognizingannual	recognizingannual	JJ
cord-016903-z2vqfq98	45	6	epidemics	epidemic	NNS
cord-016903-z2vqfq98	45	7	that	that	WDT
cord-016903-z2vqfq98	45	8	have	have	VBP
cord-016903-z2vqfq98	45	9	been	be	VBN
cord-016903-z2vqfq98	45	10	interruptedby	interruptedby	NNP
cord-016903-z2vqfq98	45	11	three	three	CD
cord-016903-z2vqfq98	45	12	pandemics	pandemic	NNS
cord-016903-z2vqfq98	45	13	(	(	-LRB-
cord-016903-z2vqfq98	45	14	Spanish	spanish	JJ
cord-016903-z2vqfq98	45	15	influenza	influenza	NN
cord-016903-z2vqfq98	45	16	,	,	,
cord-016903-z2vqfq98	45	17	HINl	HINl	NNP
cord-016903-z2vqfq98	45	18	,	,	,
cord-016903-z2vqfq98	45	19	1918	1918	CD
cord-016903-z2vqfq98	45	20	-	-	SYM
cord-016903-z2vqfq98	45	21	1919	1919	CD
cord-016903-z2vqfq98	45	22	;	;	:
cord-016903-z2vqfq98	45	23	Asian	asian	JJ
cord-016903-z2vqfq98	45	24	influenza	influenza	NN
cord-016903-z2vqfq98	45	25	,	,	,
cord-016903-z2vqfq98	45	26	H2N2	H2N2	NNP
cord-016903-z2vqfq98	45	27	,	,	,
cord-016903-z2vqfq98	45	28	1957	1957	CD
cord-016903-z2vqfq98	45	29	-	-	SYM
cord-016903-z2vqfq98	45	30	1958	1958	CD
cord-016903-z2vqfq98	45	31	andHongKonginfluenza	andHongKonginfluenza	NNP
cord-016903-z2vqfq98	45	32	,	,	,
cord-016903-z2vqfq98	45	33	H3N2	H3N2	NNP
cord-016903-z2vqfq98	45	34	,	,	,
cord-016903-z2vqfq98	45	35	1968	1968	CD
cord-016903-z2vqfq98	45	36	)	)	-RRB-
cord-016903-z2vqfq98	45	37	,	,	,
cord-016903-z2vqfq98	45	38	caused	cause	VBN
cord-016903-z2vqfq98	45	39	by	by	IN
cord-016903-z2vqfq98	45	40	new	new	JJ
cord-016903-z2vqfq98	45	41	influenza	influenza	NN
cord-016903-z2vqfq98	45	42	virus	virus	NN
cord-016903-z2vqfq98	45	43	strains	strain	VBZ
cord-016903-z2vqfq98	45	44	with	with	IN
cord-016903-z2vqfq98	45	45	increased	increase	VBN
cord-016903-z2vqfq98	45	46	virulence	virulence	NN
cord-016903-z2vqfq98	45	47	.	.	.
cord-016903-z2vqfq98	46	1	Influenza	influenza	NN
cord-016903-z2vqfq98	46	2	viruses	virus	NNS
cord-016903-z2vqfq98	46	3	are	be	VBP
cord-016903-z2vqfq98	46	4	enveloped	envelop	VBN
cord-016903-z2vqfq98	46	5	viruses	virus	NNS
cord-016903-z2vqfq98	46	6	containing	contain	VBG
cord-016903-z2vqfq98	46	7	eight	eight	CD
cord-016903-z2vqfq98	46	8	single	single	RB
cord-016903-z2vqfq98	46	9	-	-	HYPH
cord-016903-z2vqfq98	46	10	stranded	strand	VBN
cord-016903-z2vqfq98	46	11	RNA	rna	NN
cord-016903-z2vqfq98	46	12	segments	segment	NNS
cord-016903-z2vqfq98	46	13	which	which	WDT
cord-016903-z2vqfq98	46	14	encode	encode	VBP
cord-016903-z2vqfq98	46	15	for	for	IN
cord-016903-z2vqfq98	46	16	viral	viral	JJ
cord-016903-z2vqfq98	46	17	proteins	protein	NNS
cord-016903-z2vqfq98	46	18	,	,	,
cord-016903-z2vqfq98	46	19	such	such	JJ
cord-016903-z2vqfq98	46	20	as	as	IN
cord-016903-z2vqfq98	46	21	hemagglutinin	hemagglutinin	NN
cord-016903-z2vqfq98	46	22	(	(	-LRB-
cord-016903-z2vqfq98	46	23	HA	HA	NNP
cord-016903-z2vqfq98	46	24	)	)	-RRB-
cord-016903-z2vqfq98	46	25	,	,	,
cord-016903-z2vqfq98	46	26	neuraminidase	neuraminidase	FW
cord-016903-z2vqfq98	46	27	(	(	-LRB-
cord-016903-z2vqfq98	46	28	NA	NA	NNP
cord-016903-z2vqfq98	46	29	)	)	-RRB-
cord-016903-z2vqfq98	46	30	,	,	,
cord-016903-z2vqfq98	46	31	matrix	matrix	NN
cord-016903-z2vqfq98	46	32	protein	protein	NN
cord-016903-z2vqfq98	46	33	(	(	-LRB-
cord-016903-z2vqfq98	46	34	Ml	Ml	NNP
cord-016903-z2vqfq98	46	35	)	)	-RRB-
cord-016903-z2vqfq98	46	36	and	and	CC
cord-016903-z2vqfq98	46	37	nucleoprotein	nucleoprotein	NNP
cord-016903-z2vqfq98	46	38	(	(	-LRB-
cord-016903-z2vqfq98	46	39	NP	NP	NNP
cord-016903-z2vqfq98	46	40	)	)	-RRB-
cord-016903-z2vqfq98	47	1	(	(	-LRB-
cord-016903-z2vqfq98	47	2	Fig	Fig	NNP
cord-016903-z2vqfq98	47	3	.	.	NNP
cord-016903-z2vqfq98	47	4	1	1	CD
cord-016903-z2vqfq98	47	5	)	)	-RRB-
cord-016903-z2vqfq98	47	6	.	.	.
cord-016903-z2vqfq98	48	1	Influenza	influenza	NN
cord-016903-z2vqfq98	48	2	viruses	virus	NNS
cord-016903-z2vqfq98	48	3	belong	belong	VBP
cord-016903-z2vqfq98	48	4	to	to	IN
cord-016903-z2vqfq98	48	5	the	the	DT
cord-016903-z2vqfq98	48	6	family	family	NN
cord-016903-z2vqfq98	48	7	Orthomyxoviridae	Orthomyxoviridae	NNP
cord-016903-z2vqfq98	48	8	and	and	CC
cord-016903-z2vqfq98	48	9	are	be	VBP
cord-016903-z2vqfq98	48	10	divided	divide	VBN
cord-016903-z2vqfq98	48	11	into	into	IN
cord-016903-z2vqfq98	48	12	three	three	CD
cord-016903-z2vqfq98	48	13	genera	genus	NNS
cord-016903-z2vqfq98	48	14	,	,	,
cord-016903-z2vqfq98	48	15	influenza	influenza	NN
cord-016903-z2vqfq98	48	16	virus	virus	NN
cord-016903-z2vqfq98	48	17	A	A	NNP
cord-016903-z2vqfq98	48	18	,	,	,
cord-016903-z2vqfq98	48	19	B	B	NNP
cord-016903-z2vqfq98	48	20	and	and	CC
cord-016903-z2vqfq98	48	21	C	C	NNP
cord-016903-z2vqfq98	48	22	,	,	,
cord-016903-z2vqfq98	48	23	based	base	VBN
cord-016903-z2vqfq98	48	24	on	on	IN
cord-016903-z2vqfq98	48	25	antigenic	antigenic	JJ
cord-016903-z2vqfq98	48	26	differences	difference	NNS
cord-016903-z2vqfq98	48	27	in	in	IN
cord-016903-z2vqfq98	48	28	two	two	CD
cord-016903-z2vqfq98	48	29	oftheir	oftheir	JJ
cord-016903-z2vqfq98	48	30	structural	structural	JJ
cord-016903-z2vqfq98	48	31	proteins	protein	NNS
cord-016903-z2vqfq98	48	32	,	,	,
cord-016903-z2vqfq98	48	33	M	M	NNP
cord-016903-z2vqfq98	48	34	and	and	CC
cord-016903-z2vqfq98	48	35	NP	NP	NNP
cord-016903-z2vqfq98	48	36	.	.	.
cord-016903-z2vqfq98	49	1	Disease	disease	NN
cord-016903-z2vqfq98	49	2	symptoms	symptom	NNS
cord-016903-z2vqfq98	49	3	caused	cause	VBN
cord-016903-z2vqfq98	49	4	by	by	IN
cord-016903-z2vqfq98	49	5	Influenza	Influenza	NNP
cord-016903-z2vqfq98	49	6	C	C	NNP
cord-016903-z2vqfq98	49	7	are	be	VBP
cord-016903-z2vqfq98	49	8	rare	rare	JJ
cord-016903-z2vqfq98	49	9	whereas	whereas	IN
cord-016903-z2vqfq98	49	10	Influenza	Influenza	NNP
cord-016903-z2vqfq98	49	11	B	B	NNP
cord-016903-z2vqfq98	49	12	often	often	RB
cord-016903-z2vqfq98	49	13	causes	cause	VBZ
cord-016903-z2vqfq98	49	14	sporadic	sporadic	JJ
cord-016903-z2vqfq98	49	15	outbreaks	outbreak	NNS
cord-016903-z2vqfq98	49	16	,	,	,
cord-016903-z2vqfq98	49	17	especially	especially	RB
cord-016903-z2vqfq98	49	18	in	in	IN
cord-016903-z2vqfq98	49	19	residential	residential	JJ
cord-016903-z2vqfq98	49	20	communities	community	NNS
cord-016903-z2vqfq98	49	21	like	like	IN
cord-016903-z2vqfq98	49	22	nursing	nursing	NN
cord-016903-z2vqfq98	49	23	homes	home	NNS
cord-016903-z2vqfq98	49	24	.	.	.
cord-016903-z2vqfq98	50	1	Influenza	Influenza	NNP
cord-016903-z2vqfq98	50	2	A	a	DT
cord-016903-z2vqfq98	50	3	viruses	virus	NNS
cord-016903-z2vqfq98	50	4	are	be	VBP
cord-016903-z2vqfq98	50	5	further	further	RB
cord-016903-z2vqfq98	50	6	divided	divide	VBN
cord-016903-z2vqfq98	50	7	into	into	IN
cord-016903-z2vqfq98	50	8	subtypes	subtype	NNS
cord-016903-z2vqfq98	50	9	according	accord	VBG
cord-016903-z2vqfq98	50	10	to	to	IN
cord-016903-z2vqfq98	50	11	the	the	DT
cord-016903-z2vqfq98	50	12	antigenicity	antigenicity	NN
cord-016903-z2vqfq98	50	13	oftheir	oftheir	JJ
cord-016903-z2vqfq98	50	14	major	major	JJ
cord-016903-z2vqfq98	50	15	envelope	envelope	NN
cord-016903-z2vqfq98	50	16	glycoproteins	glycoprotein	NNS
cord-016903-z2vqfq98	50	17	,	,	,
cord-016903-z2vqfq98	50	18	HA	HA	NNP
cord-016903-z2vqfq98	50	19	and	and	CC
cord-016903-z2vqfq98	50	20	NA	NA	NNP
cord-016903-z2vqfq98	50	21	.	.	.
cord-016903-z2vqfq98	51	1	With	with	IN
cord-016903-z2vqfq98	51	2	at	at	IN
cord-016903-z2vqfq98	51	3	least	least	JJS
cord-016903-z2vqfq98	51	4	IS	be	VBZ
cord-016903-z2vqfq98	51	5	different	different	JJ
cord-016903-z2vqfq98	51	6	hemagglutinin	hemagglutinin	NNS
cord-016903-z2vqfq98	51	7	and	and	CC
cord-016903-z2vqfq98	51	8	9	9	CD
cord-016903-z2vqfq98	51	9	different	different	JJ
cord-016903-z2vqfq98	51	10	neuraminidase	neuraminidase	NN
cord-016903-z2vqfq98	51	11	subtypes	subtype	NNS
cord-016903-z2vqfq98	51	12	,	,	,
cord-016903-z2vqfq98	51	13	there	there	EX
cord-016903-z2vqfq98	51	14	is	be	VBZ
cord-016903-z2vqfq98	51	15	con	con	FW
cord-016903-z2vqfq98	51	16	siderable	siderable	JJ
cord-016903-z2vqfq98	51	17	antigenic	antigenic	JJ
cord-016903-z2vqfq98	51	18	variation	variation	NN
cord-016903-z2vqfq98	51	19	among	among	IN
cord-016903-z2vqfq98	51	20	influenza	influenza	NN
cord-016903-z2vqfq98	51	21	viruses	virus	NNS
cord-016903-z2vqfq98	51	22	.	.	.
cord-016903-z2vqfq98	52	1	The	the	DT
cord-016903-z2vqfq98	52	2	human	human	JJ
cord-016903-z2vqfq98	52	3	influenza	influenza	NN
cord-016903-z2vqfq98	52	4	viruses	virus	NNS
cord-016903-z2vqfq98	52	5	are	be	VBP
cord-016903-z2vqfq98	52	6	currently	currently	RB
cord-016903-z2vqfq98	52	7	limited	limit	VBN
cord-016903-z2vqfq98	52	8	to	to	IN
cord-016903-z2vqfq98	52	9	three	three	CD
cord-016903-z2vqfq98	52	10	hemagglutinin	hemagglutinin	NNS
cord-016903-z2vqfq98	52	11	(	(	-LRB-
cord-016903-z2vqfq98	52	12	H	h	NN
cord-016903-z2vqfq98	52	13	I	i	NN
cord-016903-z2vqfq98	52	14	,	,	,
cord-016903-z2vqfq98	52	15	H2	H2	NNP
cord-016903-z2vqfq98	52	16	and	and	CC
cord-016903-z2vqfq98	52	17	H3	H3	NNP
cord-016903-z2vqfq98	52	18	)	)	-RRB-
cord-016903-z2vqfq98	52	19	and	and	CC
cord-016903-z2vqfq98	52	20	two	two	CD
cord-016903-z2vqfq98	52	21	neuraminidase	neuraminidase	NN
cord-016903-z2vqfq98	52	22	subtypes	subtype	NNS
cord-016903-z2vqfq98	52	23	(	(	-LRB-
cord-016903-z2vqfq98	52	24	N	n	CD
cord-016903-z2vqfq98	52	25	1	1	CD
cord-016903-z2vqfq98	52	26	and	and	CC
cord-016903-z2vqfq98	52	27	N2	N2	NNP
cord-016903-z2vqfq98	52	28	)	)	-RRB-
cord-016903-z2vqfq98	52	29	,	,	,
cord-016903-z2vqfq98	52	30	whereas	whereas	IN
cord-016903-z2vqfq98	52	31	birds	bird	NNS
cord-016903-z2vqfq98	52	32	are	be	VBP
cord-016903-z2vqfq98	52	33	the	the	DT
cord-016903-z2vqfq98	52	34	predominant	predominant	JJ
cord-016903-z2vqfq98	52	35	hosts	host	NNS
cord-016903-z2vqfq98	52	36	for	for	IN
cord-016903-z2vqfq98	52	37	the	the	DT
cord-016903-z2vqfq98	52	38	other	other	JJ
cord-016903-z2vqfq98	52	39	subtype	subtype	NN
cord-016903-z2vqfq98	52	40	strains	strain	NNS
cord-016903-z2vqfq98	52	41	.	.	.
cord-016903-z2vqfq98	53	1	HA	HA	NNP
cord-016903-z2vqfq98	53	2	initiates	initiate	VBZ
cord-016903-z2vqfq98	53	3	viral	viral	JJ
cord-016903-z2vqfq98	53	4	infection	infection	NN
cord-016903-z2vqfq98	53	5	by	by	IN
cord-016903-z2vqfq98	53	6	binding	bind	VBG
cord-016903-z2vqfq98	53	7	to	to	IN
cord-016903-z2vqfq98	53	8	sialic	sialic	JJ
cord-016903-z2vqfq98	53	9	acid	acid	NN
cord-016903-z2vqfq98	53	10	residues	residue	NNS
cord-016903-z2vqfq98	53	11	on	on	IN
cord-016903-z2vqfq98	53	12	the	the	DT
cord-016903-z2vqfq98	53	13	carbohydrates	carbohydrate	NNS
cord-016903-z2vqfq98	53	14	ofglycoproteins	ofglycoprotein	NNS
cord-016903-z2vqfq98	53	15	present	present	JJ
cord-016903-z2vqfq98	53	16	on	on	IN
cord-016903-z2vqfq98	53	17	epithelial	epithelial	JJ
cord-016903-z2vqfq98	53	18	cells	cell	NNS
cord-016903-z2vqfq98	53	19	ofthe	ofthe	DT
cord-016903-z2vqfq98	53	20	respiratory	respiratory	JJ
cord-016903-z2vqfq98	53	21	trace	trace	NN
cord-016903-z2vqfq98	53	22	.	.	.
cord-016903-z2vqfq98	54	1	Therefore	therefore	RB
cord-016903-z2vqfq98	54	2	,	,	,
cord-016903-z2vqfq98	54	3	high	high	JJ
cord-016903-z2vqfq98	54	4	-	-	HYPH
cord-016903-z2vqfq98	54	5	affinity	affinity	NN
cord-016903-z2vqfq98	54	6	IgA	IgA	NNP
cord-016903-z2vqfq98	54	7	and	and	CC
cord-016903-z2vqfq98	54	8	IgG	IgG	NNP
cord-016903-z2vqfq98	54	9	antibodies	antibody	NNS
cord-016903-z2vqfq98	54	10	against	against	IN
cord-016903-z2vqfq98	54	11	HA	HA	NNP
cord-016903-z2vqfq98	54	12	may	may	MD
cord-016903-z2vqfq98	54	13	preven	preven	VB
cord-016903-z2vqfq98	54	14	t	t	NN
cord-016903-z2vqfq98	54	15	infection	infection	NN
cord-016903-z2vqfq98	54	16	from	from	IN
cord-016903-z2vqfq98	54	17	influenza	influenza	NN
cord-016903-z2vqfq98	54	18	virus	virus	NN
cord-016903-z2vqfq98	54	19	.	.	.
cord-016903-z2vqfq98	55	1	In	in	IN
cord-016903-z2vqfq98	55	2	contrast	contrast	NN
cord-016903-z2vqfq98	55	3	,	,	,
cord-016903-z2vqfq98	55	4	NA	NA	NNP
cord-016903-z2vqfq98	55	5	cleavesthe	cleavesthe	NNP
cord-016903-z2vqfq98	55	6	sialic	sialic	NN
cord-016903-z2vqfq98	55	7	acid	acid	NN
cord-016903-z2vqfq98	55	8	from	from	IN
cord-016903-z2vqfq98	55	9	viral	viral	JJ
cord-016903-z2vqfq98	55	10	and	and	CC
cord-016903-z2vqfq98	55	11	cellular	cellular	JJ
cord-016903-z2vqfq98	55	12	proteins	protein	NNS
cord-016903-z2vqfq98	55	13	to	to	TO
cord-016903-z2vqfq98	55	14	promote	promote	VB
cord-016903-z2vqfq98	55	15	the	the	DT
cord-016903-z2vqfq98	55	16	release	release	NN
cord-016903-z2vqfq98	55	17	of	of	IN
cord-016903-z2vqfq98	55	18	newly	newly	RB
cord-016903-z2vqfq98	55	19	synthesized	synthesize	VBN
cord-016903-z2vqfq98	55	20	influenza	influenza	NN
cord-016903-z2vqfq98	55	21	viruses	virus	NNS
cord-016903-z2vqfq98	55	22	from	from	IN
cord-016903-z2vqfq98	55	23	the	the	DT
cord-016903-z2vqfq98	55	24	infected	infected	JJ
cord-016903-z2vqfq98	55	25	host	host	NN
cord-016903-z2vqfq98	55	26	's	's	POS
cord-016903-z2vqfq98	55	27	plasma	plasma	NN
cord-016903-z2vqfq98	55	28	membrane	membrane	NN
cord-016903-z2vqfq98	55	29	.	.	.
cord-016903-z2vqfq98	56	1	Although	although	IN
cord-016903-z2vqfq98	56	2	antiviral	antiviral	JJ
cord-016903-z2vqfq98	56	3	drugs	drug	NNS
cord-016903-z2vqfq98	56	4	with	with	IN
cord-016903-z2vqfq98	56	5	moderate	moderate	JJ
cord-016903-z2vqfq98	56	6	efficacy	efficacy	NN
cord-016903-z2vqfq98	56	7	are	be	VBP
cord-016903-z2vqfq98	56	8	available	available	JJ
cord-016903-z2vqfq98	56	9	,	,	,
cord-016903-z2vqfq98	56	10	active	active	JJ
cord-016903-z2vqfq98	56	11	immunization	immunization	NN
cord-016903-z2vqfq98	56	12	represents	represent	VBZ
cord-016903-z2vqfq98	56	13	the	the	DT
cord-016903-z2vqfq98	56	14	most	most	RBS
cord-016903-z2vqfq98	56	15	vital	vital	JJ
cord-016903-z2vqfq98	56	16	element	element	NN
cord-016903-z2vqfq98	56	17	in	in	IN
cord-016903-z2vqfq98	56	18	th	th	XX
cord-016903-z2vqfq98	56	19	e	e	NN
cord-016903-z2vqfq98	56	20	prophylaxis	prophylaxis	NN
cord-016903-z2vqfq98	56	21	ofinfluenza	ofinfluenza	NN
cord-016903-z2vqfq98	56	22	disease	disease	NNP
cord-016903-z2vqfq98	56	23	.	.	.
cord-016903-z2vqfq98	57	1	However	however	RB
cord-016903-z2vqfq98	57	2	,	,	,
cord-016903-z2vqfq98	57	3	the	the	DT
cord-016903-z2vqfq98	57	4	frequently	frequently	RB
cord-016903-z2vqfq98	57	5	occurring	occur	VBG
cord-016903-z2vqfq98	57	6	antigenic	antigenic	JJ
cord-016903-z2vqfq98	57	7	driftrequires	driftrequire	NNS
cord-016903-z2vqfq98	57	8	an	an	DT
cord-016903-z2vqfq98	57	9	annual	annual	JJ
cord-016903-z2vqfq98	57	10	modification	modification	NN
cord-016903-z2vqfq98	58	1	ofthe	ofthe	DT
cord-016903-z2vqfq98	58	2	vaccinecomponents	vaccinecomponent	NNS
cord-016903-z2vqfq98	58	3	according	accord	VBG
cord-016903-z2vqfq98	58	4	to	to	IN
cord-016903-z2vqfq98	58	5	the	the	DT
cord-016903-z2vqfq98	58	6	recommendations	recommendation	NNS
cord-016903-z2vqfq98	58	7	ofthe	ofthe	DT
cord-016903-z2vqfq98	58	8	WHO	who	WP
cord-016903-z2vqfq98	58	9	.	.	.
cord-016903-z2vqfq98	59	1	Therefore	therefore	RB
cord-016903-z2vqfq98	59	2	,	,	,
cord-016903-z2vqfq98	59	3	vaccination	vaccination	NN
cord-016903-z2vqfq98	59	4	has	have	VBZ
cord-016903-z2vqfq98	59	5	to	to	TO
cord-016903-z2vqfq98	59	6	be	be	VB
cord-016903-z2vqfq98	59	7	repeated	repeat	VBN
cord-016903-z2vqfq98	59	8	annually	annually	RB
cord-016903-z2vqfq98	59	9	to	to	TO
cord-016903-z2vqfq98	59	10	ensure	ensure	VB
cord-016903-z2vqfq98	59	11	protection	protection	NN
cord-016903-z2vqfq98	59	12	against	against	IN
cord-016903-z2vqfq98	59	13	the	the	DT
cord-016903-z2vqfq98	59	14	circulating	circulate	VBG
cord-016903-z2vqfq98	59	15	influenza	influenza	NN
cord-016903-z2vqfq98	59	16	strains	strain	NNS
cord-016903-z2vqfq98	59	17	.	.	.
cord-016903-z2vqfq98	60	1	But	but	CC
cord-016903-z2vqfq98	60	2	vaccination	vaccination	NN
cord-016903-z2vqfq98	60	3	coveragediffers	coveragediffer	NNS
cord-016903-z2vqfq98	60	4	largelywithin	largelywithin	NNP
cord-016903-z2vqfq98	60	5	European	european	JJ
cord-016903-z2vqfq98	60	6	countries	country	NNS
cord-016903-z2vqfq98	60	7	.	.	.
cord-016903-z2vqfq98	61	1	In	in	IN
cord-016903-z2vqfq98	61	2	2002	2002	CD
cord-016903-z2vqfq98	61	3	,	,	,
cord-016903-z2vqfq98	61	4	the	the	DT
cord-016903-z2vqfq98	61	5	rate	rate	NN
cord-016903-z2vqfq98	61	6	ofvaccinedistribution	ofvaccinedistribution	NN
cord-016903-z2vqfq98	61	7	washighest	washighest	NN
cord-016903-z2vqfq98	61	8	in	in	IN
cord-016903-z2vqfq98	61	9	Spain	Spain	NNP
cord-016903-z2vqfq98	61	10	,	,	,
cord-016903-z2vqfq98	61	11	Belgium	Belgium	NNP
cord-016903-z2vqfq98	61	12	,	,	,
cord-016903-z2vqfq98	61	13	The	the	DT
cord-016903-z2vqfq98	61	14	Netherlands	Netherlands	NNP
cord-016903-z2vqfq98	61	15	,	,	,
cord-016903-z2vqfq98	61	16	United	United	NNP
cord-016903-z2vqfq98	61	17	Kingdom	Kingdom	NNP
cord-016903-z2vqfq98	61	18	and	and	CC
cord-016903-z2vqfq98	61	19	Germany	Germany	NNP
cord-016903-z2vqfq98	61	20	(	(	-LRB-
cord-016903-z2vqfq98	61	21	between	between	IN
cord-016903-z2vqfq98	61	22	18.1	18.1	CD
cord-016903-z2vqfq98	61	23	and	and	CC
cord-016903-z2vqfq98	61	24	20.3	20.3	CD
cord-016903-z2vqfq98	61	25	%	%	NN
cord-016903-z2vqfq98	61	26	)	)	-RRB-
cord-016903-z2vqfq98	61	27	and	and	CC
cord-016903-z2vqfq98	61	28	lowest	low	JJS
cord-016903-z2vqfq98	61	29	in	in	IN
cord-016903-z2vqfq98	61	30	Poland	Poland	NNP
cord-016903-z2vqfq98	61	31	,	,	,
cord-016903-z2vqfq98	61	32	Czech	Czech	NNP
cord-016903-z2vqfq98	61	33	Republic	Republic	NNP
cord-016903-z2vqfq98	61	34	,	,	,
cord-016903-z2vqfq98	61	35	Lithuania	Lithuania	NNP
cord-016903-z2vqfq98	61	36	and	and	CC
cord-016903-z2vqfq98	61	37	Latvia	Latvia	NNP
cord-016903-z2vqfq98	61	38	(	(	-LRB-
cord-016903-z2vqfq98	61	39	between	between	IN
cord-016903-z2vqfq98	61	40	1.9	1.9	CD
cord-016903-z2vqfq98	61	41	and	and	CC
cord-016903-z2vqfq98	61	42	7.1	7.1	CD
cord-016903-z2vqfq98	61	43	%	%	NN
cord-016903-z2vqfq98	61	44	)	)	-RRB-
cord-016903-z2vqfq98	61	45	.	.	.
cord-016903-z2vqfq98	62	1	Canada	Canada	NNP
cord-016903-z2vqfq98	62	2	and	and	CC
cord-016903-z2vqfq98	62	3	the	the	DT
cord-016903-z2vqfq98	62	4	United	United	NNP
cord-016903-z2vqfq98	62	5	States	States	NNP
cord-016903-z2vqfq98	62	6	had	have	VBD
cord-016903-z2vqfq98	62	7	the	the	DT
cord-016903-z2vqfq98	62	8	highest	high	JJS
cord-016903-z2vqfq98	62	9	rate	rate	NN
cord-016903-z2vqfq98	62	10	ofvaccine	ofvaccine	NN
cord-016903-z2vqfq98	62	11	distribution	distribution	NN
cord-016903-z2vqfq98	62	12	,	,	,
cord-016903-z2vqfq98	62	13	being	be	VBG
cord-016903-z2vqfq98	62	14	32.8	32.8	CD
cord-016903-z2vqfq98	62	15	and	and	CC
cord-016903-z2vqfq98	62	16	28.9	28.9	CD
cord-016903-z2vqfq98	62	17	%	%	NN
cord-016903-z2vqfq98	62	18	,	,	,
cord-016903-z2vqfq98	62	19	respectively	respectively	RB
cord-016903-z2vqfq98	62	20	.	.	.
cord-016903-z2vqfq98	63	1	Remarkably,70	remarkably,70	NN
cord-016903-z2vqfq98	63	2	%	%	NN
cord-016903-z2vqfq98	63	3	ofUS	ofus	JJ
cord-016903-z2vqfq98	63	4	citizens	citizen	NNS
cord-016903-z2vqfq98	63	5	aged	age	VBN
cord-016903-z2vqfq98	63	6	65	65	CD
cord-016903-z2vqfq98	63	7	and	and	CC
cord-016903-z2vqfq98	63	8	abovehave	abovehave	NNP
cord-016903-z2vqfq98	63	9	been	be	VBN
cord-016903-z2vqfq98	63	10	vaccinated	vaccinate	VBN
cord-016903-z2vqfq98	63	11	against	against	IN
cord-016903-z2vqfq98	63	12	Influenza	Influenza	NNP
cord-016903-z2vqfq98	63	13	.	.	.
cord-016903-z2vqfq98	64	1	"	"	``
cord-016903-z2vqfq98	64	2	Although	although	IN
cord-016903-z2vqfq98	64	3	there	there	EX
cord-016903-z2vqfq98	64	4	are	be	VBP
cord-016903-z2vqfq98	64	5	severalvaccinesavailable	severalvaccinesavailable	JJ
cord-016903-z2vqfq98	64	6	,	,	,
cord-016903-z2vqfq98	64	7	the	the	DT
cord-016903-z2vqfq98	64	8	efficacyofmanyvaccinesin	efficacyofmanyvaccinesin	NNP
cord-016903-z2vqfq98	64	9	preventing	prevent	VBG
cord-016903-z2vqfq98	64	10	influenza	influenza	NN
cord-016903-z2vqfq98	64	11	diseasein	diseasein	NNP
cord-016903-z2vqfq98	64	12	elderlypersons	elderlypersons	NNP
cord-016903-z2vqfq98	64	13	isonly	isonly	RB
cord-016903-z2vqfq98	64	14	around	around	IN
cord-016903-z2vqfq98	64	15	56%.9	56%.9	CD
cord-016903-z2vqfq98	64	16	Especiallyveryold	Especiallyveryold	NNP
cord-016903-z2vqfq98	64	17	and	and	CC
cord-016903-z2vqfq98	64	18	frail	frail	JJ
cord-016903-z2vqfq98	64	19	persons	person	NNS
cord-016903-z2vqfq98	64	20	show	show	VBP
cord-016903-z2vqfq98	64	21	a	a	DT
cord-016903-z2vqfq98	64	22	decreased	decrease	VBN
cord-016903-z2vqfq98	64	23	response	response	NN
cord-016903-z2vqfq98	64	24	to	to	IN
cord-016903-z2vqfq98	64	25	influenza	influenza	NN
cord-016903-z2vqfq98	64	26	vaccines	vaccine	NNS
cord-016903-z2vqfq98	64	27	.	.	.
cord-016903-z2vqfq98	65	1	P'Ihe	P'Ihe	NNP
cord-016903-z2vqfq98	65	2	reduced	reduce	VBN
cord-016903-z2vqfq98	65	3	vaccine	vaccine	NN
cord-016903-z2vqfq98	65	4	efficacyis	efficacyis	NN
cord-016903-z2vqfq98	65	5	due	due	JJ
cord-016903-z2vqfq98	65	6	to	to	IN
cord-016903-z2vqfq98	65	7	low	low	JJ
cord-016903-z2vqfq98	65	8	levelsofIgA	levelsofIgA	NNS
cord-016903-z2vqfq98	65	9	and	and	CC
cord-016903-z2vqfq98	65	10	IgGantibodies	IgGantibodies	NNP
cord-016903-z2vqfq98	65	11	,	,	,
cord-016903-z2vqfq98	65	12	delayed	delay	VBN
cord-016903-z2vqfq98	65	13	peak	peak	NN
cord-016903-z2vqfq98	65	14	antibody	antibody	NN
cord-016903-z2vqfq98	65	15	titers	titer	NNS
cord-016903-z2vqfq98	65	16	and	and	CC
cord-016903-z2vqfq98	65	17	shortened	shorten	VBN
cord-016903-z2vqfq98	65	18	maintenance	maintenance	NN
cord-016903-z2vqfq98	65	19	of	of	IN
cord-016903-z2vqfq98	65	20	titers	titer	NNS
cord-016903-z2vqfq98	65	21	after	after	IN
cord-016903-z2vqfq98	65	22	vaccination	vaccination	NN
cord-016903-z2vqfq98	65	23	.	.	.
cord-016903-z2vqfq98	66	1	Nevertheless	nevertheless	RB
cord-016903-z2vqfq98	66	2	,	,	,
cord-016903-z2vqfq98	66	3	immunization	immunization	NN
cord-016903-z2vqfq98	66	4	in	in	IN
cord-016903-z2vqfq98	66	5	elderly	elderly	JJ
cord-016903-z2vqfq98	66	6	people	people	NNS
cord-016903-z2vqfq98	66	7	has	have	VBZ
cord-016903-z2vqfq98	66	8	been	be	VBN
cord-016903-z2vqfq98	66	9	shown	show	VBN
cord-016903-z2vqfq98	66	10	to	to	TO
cord-016903-z2vqfq98	66	11	be	be	VB
cord-016903-z2vqfq98	66	12	safe	safe	JJ
cord-016903-z2vqfq98	66	13	,	,	,
cord-016903-z2vqfq98	66	14	cost	cost	NN
cord-016903-z2vqfq98	66	15	-	-	HYPH
cord-016903-z2vqfq98	66	16	effective	effective	JJ
cord-016903-z2vqfq98	66	17	and	and	CC
cord-016903-z2vqfq98	66	18	associated	associate	VBN
cord-016903-z2vqfq98	66	19	with	with	IN
cord-016903-z2vqfq98	66	20	reduced	reduced	JJ
cord-016903-z2vqfq98	66	21	rates	rate	NNS
cord-016903-z2vqfq98	66	22	ofhospitalization	ofhospitalization	NN
cord-016903-z2vqfq98	66	23	and	and	CC
cord-016903-z2vqfq98	66	24	influenza	influenza	NN
cord-016903-z2vqfq98	66	25	-	-	HYPH
cord-016903-z2vqfq98	66	26	relateddeaths	relateddeath	NNS
cord-016903-z2vqfq98	66	27	.	.	.
cord-016903-z2vqfq98	67	1	I1,12In	I1,12In	NNP
cord-016903-z2vqfq98	67	2	particular	particular	JJ
cord-016903-z2vqfq98	67	3	,	,	,
cord-016903-z2vqfq98	67	4	the	the	DT
cord-016903-z2vqfq98	67	5	efficacyofinfluenzavaccination	efficacyofinfluenzavaccination	NN
cord-016903-z2vqfq98	67	6	to	to	TO
cord-016903-z2vqfq98	67	7	reduce	reduce	VB
cord-016903-z2vqfq98	67	8	mortality	mortality	NN
cord-016903-z2vqfq98	67	9	in	in	IN
cord-016903-z2vqfq98	67	10	elderlypeople	elderlypeople	NN
cord-016903-z2vqfq98	67	11	is	be	VBZ
cord-016903-z2vqfq98	67	12	greater	great	JJR
cord-016903-z2vqfq98	67	13	after	after	IN
cord-016903-z2vqfq98	67	14	repeated	repeat	VBN
cord-016903-z2vqfq98	67	15	annual	annual	JJ
cord-016903-z2vqfq98	67	16	vaccination	vaccination	NN
cord-016903-z2vqfq98	67	17	than	than	IN
cord-016903-z2vqfq98	67	18	after	after	IN
cord-016903-z2vqfq98	67	19	first	first	JJ
cord-016903-z2vqfq98	67	20	administration	administration	NN
cord-016903-z2vqfq98	67	21	.	.	.
cord-016903-z2vqfq98	68	1	13Presently	13presently	RB
cord-016903-z2vqfq98	68	2	,	,	,
cord-016903-z2vqfq98	68	3	Influenza	influenza	NN
cord-016903-z2vqfq98	68	4	vaccines	vaccine	NNS
cord-016903-z2vqfq98	68	5	can	can	MD
cord-016903-z2vqfq98	68	6	be	be	VB
cord-016903-z2vqfq98	68	7	classifiedin	classifiedin	JJ
cord-016903-z2vqfq98	68	8	split	split	VBN
cord-016903-z2vqfq98	68	9	-	-	HYPH
cord-016903-z2vqfq98	68	10	virus	virus	NN
cord-016903-z2vqfq98	68	11	,	,	,
cord-016903-z2vqfq98	68	12	subunit	subunit	NN
cord-016903-z2vqfq98	68	13	,	,	,
cord-016903-z2vqfq98	68	14	virosomal	virosomal	JJ
cord-016903-z2vqfq98	68	15	and	and	CC
cord-016903-z2vqfq98	68	16	live	live	RB
cord-016903-z2vqfq98	68	17	-	-	HYPH
cord-016903-z2vqfq98	68	18	attenuated	attenuate	VBN
cord-016903-z2vqfq98	68	19	vaccines	vaccine	NNS
cord-016903-z2vqfq98	68	20	(	(	-LRB-
cord-016903-z2vqfq98	68	21	Table	table	NN
cord-016903-z2vqfq98	68	22	2	2	CD
cord-016903-z2vqfq98	68	23	)	)	-RRB-
cord-016903-z2vqfq98	68	24	.	.	.
cord-016903-z2vqfq98	69	1	Split	split	NN
cord-016903-z2vqfq98	69	2	-	-	HYPH
cord-016903-z2vqfq98	69	3	virus	virus	NN
cord-016903-z2vqfq98	69	4	vaccines	vaccine	NNS
cord-016903-z2vqfq98	69	5	are	be	VBP
cord-016903-z2vqfq98	69	6	used	use	VBN
cord-016903-z2vqfq98	69	7	since	since	IN
cord-016903-z2vqfq98	69	8	the	the	DT
cord-016903-z2vqfq98	69	9	1980s	1980	NNS
cord-016903-z2vqfq98	69	10	,	,	,
cord-016903-z2vqfq98	69	11	are	be	VBP
cord-016903-z2vqfq98	69	12	cheap	cheap	JJ
cord-016903-z2vqfq98	69	13	and	and	CC
cord-016903-z2vqfq98	69	14	offer	offer	VBP
cord-016903-z2vqfq98	69	15	a	a	DT
cord-016903-z2vqfq98	69	16	good	good	JJ
cord-016903-z2vqfq98	69	17	protection	protection	NN
cord-016903-z2vqfq98	69	18	for	for	IN
cord-016903-z2vqfq98	69	19	children	child	NNS
cord-016903-z2vqfq98	69	20	above	above	IN
cord-016903-z2vqfq98	69	21	6	6	CD
cord-016903-z2vqfq98	69	22	months	month	NNS
cord-016903-z2vqfq98	69	23	of	of	IN
cord-016903-z2vqfq98	69	24	age	age	NN
cord-016903-z2vqfq98	69	25	and	and	CC
cord-016903-z2vqfq98	69	26	adults	adult	NNS
cord-016903-z2vqfq98	69	27	.	.	.
cord-016903-z2vqfq98	70	1	Recently	recently	RB
cord-016903-z2vqfq98	70	2	,	,	,
cord-016903-z2vqfq98	70	3	subunit	subunit	NN
cord-016903-z2vqfq98	70	4	vaccines	vaccine	NNS
cord-016903-z2vqfq98	70	5	with	with	IN
cord-016903-z2vqfq98	70	6	new	new	JJ
cord-016903-z2vqfq98	70	7	adjuvants	adjuvant	NNS
cord-016903-z2vqfq98	70	8	have	have	VBP
cord-016903-z2vqfq98	70	9	been	be	VBN
cord-016903-z2vqfq98	70	10	developed	develop	VBN
cord-016903-z2vqfq98	70	11	(	(	-LRB-
cord-016903-z2vqfq98	70	12	FluadO	FluadO	NNP
cord-016903-z2vqfq98	70	13	,	,	,
cord-016903-z2vqfq98	70	14	Addigrip	Addigrip	NNP
cord-016903-z2vqfq98	70	15	'	'	''
cord-016903-z2vqfq98	70	16	)	)	-RRB-
cord-016903-z2vqfq98	70	17	that	that	WDT
cord-016903-z2vqfq98	70	18	show	show	VBP
cord-016903-z2vqfq98	70	19	an	an	DT
cord-016903-z2vqfq98	70	20	increased	increase	VBN
cord-016903-z2vqfq98	70	21	immunogcnicity	immunogcnicity	NN
cord-016903-z2vqfq98	70	22	,	,	,
cord-016903-z2vqfq98	70	23	a	a	DT
cord-016903-z2vqfq98	70	24	favorable	favorable	JJ
cord-016903-z2vqfq98	70	25	safety	safety	NN
cord-016903-z2vqfq98	70	26	profile	profile	NN
cord-016903-z2vqfq98	70	27	and	and	CC
cord-016903-z2vqfq98	70	28	may	may	MD
cord-016903-z2vqfq98	70	29	be	be	VB
cord-016903-z2vqfq98	70	30	more	more	RBR
cord-016903-z2vqfq98	70	31	suitable	suitable	JJ
cord-016903-z2vqfq98	70	32	for	for	IN
cord-016903-z2vqfq98	70	33	the	the	DT
cord-016903-z2vqfq98	70	34	vaccination	vaccination	NN
cord-016903-z2vqfq98	70	35	of	of	IN
cord-016903-z2vqfq98	70	36	elderly	elderly	JJ
cord-016903-z2vqfq98	70	37	persons	person	NNS
cord-016903-z2vqfq98	70	38	.	.	.
cord-016903-z2vqfq98	70	39	'	'	''
cord-016903-z2vqfq98	70	40	!	!	.
cord-016903-z2vqfq98	71	1	Additionally	additionally	RB
cord-016903-z2vqfq98	71	2	,	,	,
cord-016903-z2vqfq98	71	3	invariant	invariant	JJ
cord-016903-z2vqfq98	71	4	antigens	antigen	NNS
cord-016903-z2vqfq98	71	5	,	,	,
cord-016903-z2vqfq98	71	6	such	such	JJ
cord-016903-z2vqfq98	71	7	as	as	IN
cord-016903-z2vqfq98	71	8	M	M	NNP
cord-016903-z2vqfq98	71	9	1	1	CD
cord-016903-z2vqfq98	71	10	and	and	CC
cord-016903-z2vqfq98	71	11	NP	NP	NNP
cord-016903-z2vqfq98	71	12	,	,	,
cord-016903-z2vqfq98	71	13	may	may	MD
cord-016903-z2vqfq98	71	14	also	also	RB
cord-016903-z2vqfq98	71	15	play	play	VB
cord-016903-z2vqfq98	71	16	an	an	DT
cord-016903-z2vqfq98	71	17	important	important	JJ
cord-016903-z2vqfq98	71	18	role	role	NN
cord-016903-z2vqfq98	71	19	in	in	IN
cord-016903-z2vqfq98	71	20	protection	protection	NN
cord-016903-z2vqfq98	71	21	and	and	CC
cord-016903-z2vqfq98	71	22	could	could	MD
cord-016903-z2vqfq98	71	23	be	be	VB
cord-016903-z2vqfq98	71	24	used	use	VBN
cord-016903-z2vqfq98	71	25	in	in	IN
cord-016903-z2vqfq98	71	26	vaccines	vaccine	NNS
cord-016903-z2vqfq98	71	27	to	to	TO
cord-016903-z2vqfq98	71	28	induce	induce	VB
cord-016903-z2vqfq98	71	29	long	long	RB
cord-016903-z2vqfq98	71	30	-	-	HYPH
cord-016903-z2vqfq98	71	31	lasting	last	VBG
cord-016903-z2vqfq98	71	32	immunity	immunity	NN
cord-016903-z2vqfq98	71	33	to	to	IN
cord-016903-z2vqfq98	71	34	a	a	DT
cord-016903-z2vqfq98	71	35	variety	variety	NN
cord-016903-z2vqfq98	71	36	of	of	IN
cord-016903-z2vqfq98	71	37	different	different	JJ
cord-016903-z2vqfq98	71	38	influenza	influenza	NN
cord-016903-z2vqfq98	71	39	strains	strain	NNS
cord-016903-z2vqfq98	71	40	.	.	.
cord-016903-z2vqfq98	72	1	Another	another	DT
cord-016903-z2vqfq98	72	2	strategy	strategy	NN
cord-016903-z2vqfq98	72	3	to	to	TO
cord-016903-z2vqfq98	72	4	enhance	enhance	VB
cord-016903-z2vqfq98	72	5	immunogenicity	immunogenicity	NN
cord-016903-z2vqfq98	72	6	may	may	MD
cord-016903-z2vqfq98	72	7	the	the	DT
cord-016903-z2vqfq98	72	8	use	use	NN
cord-016903-z2vqfq98	72	9	ofvirosomes	ofvirosome	NNS
cord-016903-z2vqfq98	72	10	that	that	WDT
cord-016903-z2vqfq98	72	11	are	be	VBP
cord-016903-z2vqfq98	72	12	nontoxic	nontoxic	JJ
cord-016903-z2vqfq98	72	13	,	,	,
cord-016903-z2vqfq98	72	14	biodegradable	biodegradable	JJ
cord-016903-z2vqfq98	72	15	lipid	lipid	NN
cord-016903-z2vqfq98	72	16	-	-	HYPH
cord-016903-z2vqfq98	72	17	basedantigen	basedantigen	NN
cord-016903-z2vqfq98	72	18	-	-	HYPH
cord-016903-z2vqfq98	72	19	presentation	presentation	NN
cord-016903-z2vqfq98	72	20	systems	system	NNS
cord-016903-z2vqfq98	72	21	.	.	.
cord-016903-z2vqfq98	72	22	"	"	''
cord-016903-z2vqfq98	73	1	Virosomal	Virosomal	NNP
cord-016903-z2vqfq98	73	2	influenzavaccines	influenzavaccine	NNS
cord-016903-z2vqfq98	73	3	,	,	,
cord-016903-z2vqfq98	73	4	such	such	JJ
cord-016903-z2vqfq98	73	5	asInflexalV	asInflexalV	NNP
cord-016903-z2vqfq98	73	6	'	'	''
cord-016903-z2vqfq98	73	7	,	,	.
cord-016903-z2vqfq98	74	1	InfIuvac	InfIuvac	NNP
cord-016903-z2vqfq98	74	2	Plus'and	Plus'and	NNP
cord-016903-z2vqfq98	74	3	Invivac'have	Invivac'have	NNP
cord-016903-z2vqfq98	74	4	been	be	VBN
cord-016903-z2vqfq98	74	5	on	on	IN
cord-016903-z2vqfq98	74	6	the	the	DT
cord-016903-z2vqfq98	74	7	market	market	NN
cord-016903-z2vqfq98	74	8	in	in	IN
cord-016903-z2vqfq98	74	9	several	several	JJ
cord-016903-z2vqfq98	74	10	European	european	JJ
cord-016903-z2vqfq98	74	11	countries	country	NNS
cord-016903-z2vqfq98	74	12	for	for	IN
cord-016903-z2vqfq98	74	13	a	a	DT
cord-016903-z2vqfq98	74	14	number	number	NN
cord-016903-z2vqfq98	74	15	of	of	IN
cord-016903-z2vqfq98	74	16	years	year	NNS
cord-016903-z2vqfq98	74	17	.	.	.
cord-016903-z2vqfq98	75	1	They	-PRON-	PRP
cord-016903-z2vqfq98	75	2	display	display	VBP
cord-016903-z2vqfq98	75	3	a	a	DT
cord-016903-z2vqfq98	75	4	high	high	JJ
cord-016903-z2vqfq98	75	5	immunogenicity	immunogenicity	NN
cord-016903-z2vqfq98	75	6	and	and	CC
cord-016903-z2vqfq98	75	7	a	a	DT
cord-016903-z2vqfq98	75	8	similar	similar	JJ
cord-016903-z2vqfq98	75	9	safety	safety	NN
cord-016903-z2vqfq98	75	10	profile	profile	NN
cord-016903-z2vqfq98	75	11	in	in	IN
cord-016903-z2vqfq98	75	12	elderly	elderly	JJ
cord-016903-z2vqfq98	75	13	persons	person	NNS
cord-016903-z2vqfq98	75	14	compared	compare	VBN
cord-016903-z2vqfq98	75	15	with	with	IN
cord-016903-z2vqfq98	75	16	inactivated	inactivate	VBN
cord-016903-z2vqfq98	75	17	influenza	influenza	NN
cord-016903-z2vqfq98	75	18	vaccines	vaccine	NNS
cord-016903-z2vqfq98	75	19	.	.	.
cord-016903-z2vqfq98	76	1	F	F	NNP
cord-016903-z2vqfq98	76	2	"	"	``
cord-016903-z2vqfq98	76	3	Furthermore	furthermore	RB
cord-016903-z2vqfq98	76	4	,	,	,
cord-016903-z2vqfq98	76	5	new	new	JJ
cord-016903-z2vqfq98	76	6	live	live	RB
cord-016903-z2vqfq98	76	7	-	-	HYPH
cord-016903-z2vqfq98	76	8	attenuated	attenuate	VBN
cord-016903-z2vqfq98	76	9	and	and	CC
cord-016903-z2vqfq98	76	10	subunit	subunit	NN
cord-016903-z2vqfq98	76	11	influenza	influenza	NN
cord-016903-z2vqfq98	76	12	vaccines	vaccine	NNS
cord-016903-z2vqfq98	76	13	ate	eat	VBD
cord-016903-z2vqfq98	76	14	currently	currently	RB
cord-016903-z2vqfq98	76	15	in	in	IN
cord-016903-z2vqfq98	76	16	clinical	clinical	JJ
cord-016903-z2vqfq98	76	17	trials	trial	NNS
cord-016903-z2vqfq98	76	18	that	that	WDT
cord-016903-z2vqfq98	76	19	promise	promise	VBP
cord-016903-z2vqfq98	76	20	to	to	TO
cord-016903-z2vqfq98	76	21	have	have	VB
cord-016903-z2vqfq98	76	22	an	an	DT
cord-016903-z2vqfq98	76	23	increased	increase	VBN
cord-016903-z2vqfq98	76	24	efficacy	efficacy	NN
cord-016903-z2vqfq98	76	25	ofprotection	ofprotection	NN
cord-016903-z2vqfq98	76	26	(	(	-LRB-
cord-016903-z2vqfq98	76	27	Table	table	NN
cord-016903-z2vqfq98	76	28	 	 	_SP
cord-016903-z2vqfq98	76	29	1	1	CD
cord-016903-z2vqfq98	76	30	)	)	-RRB-
cord-016903-z2vqfq98	76	31	.	.	.
cord-016903-z2vqfq98	77	1	Especially	especially	RB
cord-016903-z2vqfq98	77	2	live	live	RB
cord-016903-z2vqfq98	77	3	-	-	HYPH
cord-016903-z2vqfq98	77	4	attenuated	attenuate	VBN
cord-016903-z2vqfq98	77	5	influenza	influenza	NN
cord-016903-z2vqfq98	77	6	vaccines	vaccine	NNS
cord-016903-z2vqfq98	77	7	ate	eat	VBD
cord-016903-z2vqfq98	77	8	believed	believe	VBN
cord-016903-z2vqfq98	77	9	to	to	TO
cord-016903-z2vqfq98	77	10	elicit	elicit	VB
cord-016903-z2vqfq98	77	11	strong	strong	JJ
cord-016903-z2vqfq98	77	12	Tcel	Tcel	NNP
cord-016903-z2vqfq98	77	13	!	!	.
cord-016903-z2vqfq98	78	1	responses	response	NNS
cord-016903-z2vqfq98	78	2	and	and	CC
cord-016903-z2vqfq98	78	3	should	should	MD
cord-016903-z2vqfq98	78	4	be	be	VB
cord-016903-z2vqfq98	78	5	able	able	JJ
cord-016903-z2vqfq98	78	6	to	to	TO
cord-016903-z2vqfq98	78	7	enhance	enhance	VB
cord-016903-z2vqfq98	78	8	antibody	antibody	NN
cord-016903-z2vqfq98	78	9	levels	level	NNS
cord-016903-z2vqfq98	78	10	after	after	IN
cord-016903-z2vqfq98	78	11	vaccination	vaccination	NN
cord-016903-z2vqfq98	78	12	.	.	.
cord-016903-z2vqfq98	79	1	Importantly	importantly	RB
cord-016903-z2vqfq98	79	2	,	,	,
cord-016903-z2vqfq98	79	3	before	before	IN
cord-016903-z2vqfq98	79	4	administration	administration	NN
cord-016903-z2vqfq98	79	5	of	of	IN
cord-016903-z2vqfq98	79	6	live	live	RB
cord-016903-z2vqfq98	79	7	-	-	HYPH
cord-016903-z2vqfq98	79	8	attenuated	attenuate	VBN
cord-016903-z2vqfq98	79	9	vaccines	vaccine	NNS
cord-016903-z2vqfq98	79	10	to	to	IN
cord-016903-z2vqfq98	79	11	elderly	elderly	JJ
cord-016903-z2vqfq98	79	12	or	or	CC
cord-016903-z2vqfq98	79	13	immunocompromised	immunocompromised	JJ
cord-016903-z2vqfq98	79	14	persons	person	NNS
cord-016903-z2vqfq98	79	15	,	,	,
cord-016903-z2vqfq98	79	16	an	an	DT
cord-016903-z2vqfq98	79	17	acceptable	acceptable	JJ
cord-016903-z2vqfq98	79	18	safety	safety	NN
cord-016903-z2vqfq98	79	19	profile	profile	NN
cord-016903-z2vqfq98	79	20	has	have	VBZ
cord-016903-z2vqfq98	79	21	to	to	TO
cord-016903-z2vqfq98	79	22	be	be	VB
cord-016903-z2vqfq98	79	23	demonstrated	demonstrate	VBN
cord-016903-z2vqfq98	79	24	.	.	.
cord-016903-z2vqfq98	80	1	Irrespective	irrespective	RB
cord-016903-z2vqfq98	80	2	ofthe	ofthe	DT
cord-016903-z2vqfq98	80	3	improvement	improvement	NN
cord-016903-z2vqfq98	80	4	ofinfluenza	ofinfluenza	IN
cord-016903-z2vqfq98	80	5	vaccines	vaccine	NNS
cord-016903-z2vqfq98	80	6	for	for	IN
cord-016903-z2vqfq98	80	7	elderly	elderly	JJ
cord-016903-z2vqfq98	80	8	persons	person	NNS
cord-016903-z2vqfq98	80	9	,	,	,
cord-016903-z2vqfq98	80	10	vaccination	vaccination	NN
cord-016903-z2vqfq98	80	11	of	of	IN
cord-016903-z2vqfq98	80	12	children	child	NNS
cord-016903-z2vqfq98	80	13	is	be	VBZ
cord-016903-z2vqfq98	80	14	clinically	clinically	RB
cord-016903-z2vqfq98	80	15	effective	effective	JJ
cord-016903-z2vqfq98	80	16	'	'	''
cord-016903-z2vqfq98	80	17	"	"	''
cord-016903-z2vqfq98	80	18	and	and	CC
cord-016903-z2vqfq98	80	19	high	high	JJ
cord-016903-z2vqfq98	80	20	vaccination	vaccination	NN
cord-016903-z2vqfq98	80	21	coverage	coverage	NN
cord-016903-z2vqfq98	80	22	among	among	IN
cord-016903-z2vqfq98	80	23	pupils	pupil	NNS
cord-016903-z2vqfq98	80	24	has	have	VBZ
cord-016903-z2vqfq98	80	25	demonstrated	demonstrate	VBN
cord-016903-z2vqfq98	80	26	to	to	TO
cord-016903-z2vqfq98	80	27	induce	induce	VB
cord-016903-z2vqfq98	80	28	herd	herd	NN
cord-016903-z2vqfq98	80	29	immunity	immunity	NN
cord-016903-z2vqfq98	80	30	and	and	CC
cord-016903-z2vqfq98	80	31	to	to	TO
cord-016903-z2vqfq98	80	32	reduce	reduce	VB
cord-016903-z2vqfq98	80	33	mortality	mortality	NN
cord-016903-z2vqfq98	80	34	in	in	IN
cord-016903-z2vqfq98	80	35	older	old	JJR
cord-016903-z2vqfq98	80	36	adults	adult	NNS
cord-016903-z2vqfq98	80	37	.	.	.
cord-016903-z2vqfq98	81	1	Streptococcus	streptococcus	NN
cord-016903-z2vqfq98	81	2	pneumoniae	pneumoniae	NN
cord-016903-z2vqfq98	81	3	is	be	VBZ
cord-016903-z2vqfq98	81	4	an	an	DT
cord-016903-z2vqfq98	81	5	important	important	JJ
cord-016903-z2vqfq98	81	6	cause	cause	NN
cord-016903-z2vqfq98	81	7	of	of	IN
cord-016903-z2vqfq98	81	8	invasive	invasive	JJ
cord-016903-z2vqfq98	81	9	clinical	clinical	JJ
cord-016903-z2vqfq98	81	10	manifestations	manifestation	NNS
cord-016903-z2vqfq98	81	11	such	such	JJ
cord-016903-z2vqfq98	81	12	as	as	IN
cord-016903-z2vqfq98	81	13	bacterial	bacterial	JJ
cord-016903-z2vqfq98	81	14	pneumonia	pneumonia	NN
cord-016903-z2vqfq98	81	15	,	,	,
cord-016903-z2vqfq98	81	16	meningitis	meningitis	NN
cord-016903-z2vqfq98	81	17	and	and	CC
cord-016903-z2vqfq98	81	18	septicemia	septicemia	NN
cord-016903-z2vqfq98	81	19	,	,	,
cord-016903-z2vqfq98	81	20	particularly	particularly	RB
cord-016903-z2vqfq98	81	21	in	in	IN
cord-016903-z2vqfq98	81	22	young	young	JJ
cord-016903-z2vqfq98	81	23	children	child	NNS
cord-016903-z2vqfq98	81	24	and	and	CC
cord-016903-z2vqfq98	81	25	the	the	DT
cord-016903-z2vqfq98	81	26	elderly	elderly	JJ
cord-016903-z2vqfq98	81	27	.	.	.
cord-016903-z2vqfq98	82	1	80	80	CD
cord-016903-z2vqfq98	82	2	to	to	TO
cord-016903-z2vqfq98	82	3	90	90	CD
cord-016903-z2vqfq98	82	4	%	%	NN
cord-016903-z2vqfq98	82	5	ofdeaths	ofdeath	NNS
cord-016903-z2vqfq98	82	6	associated	associate	VBN
cord-016903-z2vqfq98	82	7	with	with	IN
cord-016903-z2vqfq98	82	8	Streptococcus	streptococcus	NN
cord-016903-z2vqfq98	82	9	pneumoniaeinfection	pneumoniaeinfection	NN
cord-016903-z2vqfq98	82	10	occur	occur	VBP
cord-016903-z2vqfq98	82	11	in	in	IN
cord-016903-z2vqfq98	82	12	people	people	NNS
cord-016903-z2vqfq98	82	13	aged	age	VBN
cord-016903-z2vqfq98	82	14	60	60	CD
cord-016903-z2vqfq98	82	15	years	year	NNS
cord-016903-z2vqfq98	82	16	and	and	CC
cord-016903-z2vqfq98	82	17	above	above	RB
cord-016903-z2vqfq98	82	18	.	.	.
cord-016903-z2vqfq98	83	1	Several	several	JJ
cord-016903-z2vqfq98	83	2	further	further	JJ
cord-016903-z2vqfq98	83	3	groups	group	NNS
cord-016903-z2vqfq98	83	4	at	at	IN
cord-016903-z2vqfq98	83	5	higher	high	JJR
cord-016903-z2vqfq98	83	6	risk	risk	NN
cord-016903-z2vqfq98	84	1	ofinvasive	ofinvasive	NNP
cord-016903-z2vqfq98	84	2	pneumococcal	pneumococcal	JJ
cord-016903-z2vqfq98	84	3	disease	disease	NN
cord-016903-z2vqfq98	84	4	have	have	VBP
cord-016903-z2vqfq98	84	5	been	be	VBN
cord-016903-z2vqfq98	84	6	defined	define	VBN
cord-016903-z2vqfq98	84	7	,	,	,
cord-016903-z2vqfq98	84	8	including	include	VBG
cord-016903-z2vqfq98	84	9	individuals	individual	NNS
cord-016903-z2vqfq98	84	10	with	with	IN
cord-016903-z2vqfq98	84	11	splenic	splenic	JJ
cord-016903-z2vqfq98	84	12	dysfunction	dysfunction	NN
cord-016903-z2vqfq98	84	13	,	,	,
cord-016903-z2vqfq98	84	14	immunosuppression	immunosuppression	NN
cord-016903-z2vqfq98	84	15	,	,	,
cord-016903-z2vqfq98	84	16	chronic	chronic	JJ
cord-016903-z2vqfq98	84	17	pulmonary	pulmonary	JJ
cord-016903-z2vqfq98	84	18	or	or	CC
cord-016903-z2vqfq98	84	19	cardiac	cardiac	JJ
cord-016903-z2vqfq98	84	20	disease	disease	NN
cord-016903-z2vqfq98	84	21	,	,	,
cord-016903-z2vqfq98	84	22	diabetes	diabete	VBZ
cord-016903-z2vqfq98	84	23	mellitus	mellitus	NN
cord-016903-z2vqfq98	84	24	and	and	CC
cord-016903-z2vqfq98	84	25	chronic	chronic	JJ
cord-016903-z2vqfq98	84	26	liver	liver	NN
cord-016903-z2vqfq98	84	27	disease	disease	NN
cord-016903-z2vqfq98	84	28	.	.	.
cord-016903-z2vqfq98	85	1	Generally	generally	RB
cord-016903-z2vqfq98	85	2	,	,	,
cord-016903-z2vqfq98	85	3	antibiotic	antibiotic	JJ
cord-016903-z2vqfq98	85	4	therapy	therapy	NN
cord-016903-z2vqfq98	85	5	has	have	VBZ
cord-016903-z2vqfq98	85	6	to	to	TO
cord-016903-z2vqfq98	85	7	be	be	VB
cord-016903-z2vqfq98	85	8	initiated	initiate	VBN
cord-016903-z2vqfq98	85	9	as	as	RB
cord-016903-z2vqfq98	85	10	soon	soon	RB
cord-016903-z2vqfq98	85	11	as	as	IN
cord-016903-z2vqfq98	85	12	possible	possible	JJ
cord-016903-z2vqfq98	85	13	to	to	TO
cord-016903-z2vqfq98	85	14	reduce	reduce	VB
cord-016903-z2vqfq98	85	15	the	the	DT
cord-016903-z2vqfq98	85	16	risk	risk	NN
cord-016903-z2vqfq98	85	17	ofcomplications	ofcomplication	NNS
cord-016903-z2vqfq98	85	18	due	due	IN
cord-016903-z2vqfq98	85	19	to	to	IN
cord-016903-z2vqfq98	85	20	pneumonia	pneumonia	NN
cord-016903-z2vqfq98	85	21	,	,	,
cord-016903-z2vqfq98	85	22	meningitis	meningitis	NN
cord-016903-z2vqfq98	85	23	or	or	CC
cord-016903-z2vqfq98	85	24	sepsis	sepsis	NN
cord-016903-z2vqfq98	85	25	.	.	.
cord-016903-z2vqfq98	86	1	Nonetheless	nonetheless	RB
cord-016903-z2vqfq98	86	2	,	,	,
cord-016903-z2vqfq98	86	3	50	50	CD
cord-016903-z2vqfq98	86	4	%	%	NN
cord-016903-z2vqfq98	86	5	ofall	ofall	NN
cord-016903-z2vqfq98	86	6	deaths	death	NNS
cord-016903-z2vqfq98	86	7	occur	occur	VBP
cord-016903-z2vqfq98	86	8	within	within	IN
cord-016903-z2vqfq98	86	9	the	the	DT
cord-016903-z2vqfq98	86	10	first	first	JJ
cord-016903-z2vqfq98	86	11	48	48	CD
cord-016903-z2vqfq98	86	12	hours	hour	NNS
cord-016903-z2vqfq98	86	13	despite	despite	IN
cord-016903-z2vqfq98	86	14	adequate	adequate	JJ
cord-016903-z2vqfq98	86	15	antibiotic	antibiotic	JJ
cord-016903-z2vqfq98	86	16	therapy	therapy	NN
cord-016903-z2vqfq98	86	17	.	.	.
cord-016903-z2vqfq98	87	1	This	this	DT
cord-016903-z2vqfq98	87	2	may	may	MD
cord-016903-z2vqfq98	87	3	be	be	VB
cord-016903-z2vqfq98	87	4	due	due	JJ
cord-016903-z2vqfq98	87	5	to	to	IN
cord-016903-z2vqfq98	87	6	the	the	DT
cord-016903-z2vqfq98	87	7	increased	increase	VBN
cord-016903-z2vqfq98	87	8	occurrence	occurrence	NN
cord-016903-z2vqfq98	87	9	of	of	IN
cord-016903-z2vqfq98	87	10	multiple	multiple	JJ
cord-016903-z2vqfq98	87	11	drug	drug	NN
cord-016903-z2vqfq98	87	12	-	-	HYPH
cord-016903-z2vqfq98	87	13	resistant	resistant	JJ
cord-016903-z2vqfq98	87	14	pneumococcal	pneumococcal	JJ
cord-016903-z2vqfq98	87	15	strains	strain	NNS
cord-016903-z2vqfq98	87	16	.	.	.
cord-016903-z2vqfq98	88	1	In	in	IN
cord-016903-z2vqfq98	88	2	2002	2002	CD
cord-016903-z2vqfq98	88	3	,	,	,
cord-016903-z2vqfq98	88	4	the	the	DT
cord-016903-z2vqfq98	88	5	proportion	proportion	NN
cord-016903-z2vqfq98	88	6	ofpenicillin	ofpenicillin	JJ
cord-016903-z2vqfq98	88	7	-	-	HYPH
cord-016903-z2vqfq98	88	8	resistant	resistant	JJ
cord-016903-z2vqfq98	88	9	Streptococcus	Streptococcus	NNP
cord-016903-z2vqfq98	88	10	pneumoniaewas	pneumoniaewas	NN
cord-016903-z2vqfq98	88	11	reported	report	VBD
cord-016903-z2vqfq98	88	12	to	to	TO
cord-016903-z2vqfq98	88	13	be	be	VB
cord-016903-z2vqfq98	88	14	53	53	CD
cord-016903-z2vqfq98	88	15	%	%	NN
cord-016903-z2vqfq98	88	16	in	in	IN
cord-016903-z2vqfq98	88	17	France	France	NNP
cord-016903-z2vqfq98	88	18	and	and	CC
cord-016903-z2vqfq98	88	19	more	more	JJR
cord-016903-z2vqfq98	88	20	than	than	IN
cord-016903-z2vqfq98	88	21	25	25	CD
cord-016903-z2vqfq98	88	22	%	%	NN
cord-016903-z2vqfq98	88	23	in	in	IN
cord-016903-z2vqfq98	88	24	Israel	Israel	NNP
cord-016903-z2vqfq98	88	25	,	,	,
cord-016903-z2vqfq98	88	26	Poland	Poland	NNP
cord-016903-z2vqfq98	88	27	,	,	,
cord-016903-z2vqfq98	88	28	Romania	Romania	NNP
cord-016903-z2vqfq98	88	29	and	and	CC
cord-016903-z2vqfq98	88	30	Spain	Spain	NNP
cord-016903-z2vqfq98	88	31	.	.	.
cord-016903-z2vqfq98	88	32	"	"	''
cord-016903-z2vqfq98	89	1	After	after	IN
cord-016903-z2vqfq98	89	2	recovering	recover	VBG
cord-016903-z2vqfq98	89	3	from	from	IN
cord-016903-z2vqfq98	89	4	pneumococcal	pneumococcal	JJ
cord-016903-z2vqfq98	89	5	infection	infection	NN
cord-016903-z2vqfq98	89	6	,	,	,
cord-016903-z2vqfq98	89	7	people	people	NNS
cord-016903-z2vqfq98	89	8	are	be	VBP
cord-016903-z2vqfq98	89	9	not	not	RB
cord-016903-z2vqfq98	89	10	necessarily	necessarily	RB
cord-016903-z2vqfq98	89	11	immune	immune	JJ
cord-016903-z2vqfq98	89	12	,	,	,
cord-016903-z2vqfq98	89	13	because	because	IN
cord-016903-z2vqfq98	89	14	there	there	EX
cord-016903-z2vqfq98	89	15	are	be	VBP
cord-016903-z2vqfq98	89	16	about	about	RB
cord-016903-z2vqfq98	89	17	90	90	CD
cord-016903-z2vqfq98	89	18	different	different	JJ
cord-016903-z2vqfq98	89	19	serotypes	serotype	NNS
cord-016903-z2vqfq98	89	20	and	and	CC
cord-016903-z2vqfq98	89	21	immunity	immunity	NN
cord-016903-z2vqfq98	89	22	will	will	MD
cord-016903-z2vqfq98	89	23	be	be	VB
cord-016903-z2vqfq98	89	24	guaranteed	guarantee	VBN
cord-016903-z2vqfq98	89	25	only	only	RB
cord-016903-z2vqfq98	89	26	to	to	IN
cord-016903-z2vqfq98	89	27	the	the	DT
cord-016903-z2vqfq98	89	28	strain	strain	NN
cord-016903-z2vqfq98	89	29	that	that	WDT
cord-016903-z2vqfq98	89	30	has	have	VBZ
cord-016903-z2vqfq98	89	31	caused	cause	VBN
cord-016903-z2vqfq98	89	32	the	the	DT
cord-016903-z2vqfq98	89	33	infection	infection	NN
cord-016903-z2vqfq98	89	34	.	.	.
cord-016903-z2vqfq98	90	1	Currently	currently	RB
cord-016903-z2vqfq98	90	2	,	,	,
cord-016903-z2vqfq98	90	3	pneumococcal	pneumococcal	JJ
cord-016903-z2vqfq98	90	4	vaccines	vaccine	NNS
cord-016903-z2vqfq98	90	5	are	be	VBP
cord-016903-z2vqfq98	90	6	available	available	JJ
cord-016903-z2vqfq98	90	7	that	that	IN
cord-016903-z2vqfq98	90	8	include	include	VBP
cord-016903-z2vqfq98	90	9	up	up	IN
cord-016903-z2vqfq98	90	10	to	to	TO
cord-016903-z2vqfq98	90	11	23	23	CD
cord-016903-z2vqfq98	90	12	strains	strain	NNS
cord-016903-z2vqfq98	90	13	which	which	WDT
cord-016903-z2vqfq98	90	14	are	be	VBP
cord-016903-z2vqfq98	90	15	responsible	responsible	JJ
cord-016903-z2vqfq98	90	16	to	to	TO
cord-016903-z2vqfq98	90	17	cause	cause	VB
cord-016903-z2vqfq98	90	18	disease	disease	NN
cord-016903-z2vqfq98	90	19	in	in	IN
cord-016903-z2vqfq98	90	20	almost	almost	RB
cord-016903-z2vqfq98	90	21	90	90	CD
cord-016903-z2vqfq98	90	22	%	%	NN
cord-016903-z2vqfq98	90	23	ofall	ofall	NN
cord-016903-z2vqfq98	90	24	cases	case	NNS
cord-016903-z2vqfq98	90	25	(	(	-LRB-
cord-016903-z2vqfq98	90	26	Table	table	NN
cord-016903-z2vqfq98	90	27	2	2	CD
cord-016903-z2vqfq98	90	28	)	)	-RRB-
cord-016903-z2vqfq98	90	29	.	.	.
cord-016903-z2vqfq98	91	1	These	these	DT
cord-016903-z2vqfq98	91	2	vaccines	vaccine	NNS
cord-016903-z2vqfq98	91	3	offer	offer	VBP
cord-016903-z2vqfq98	91	4	protection	protection	NN
cord-016903-z2vqfq98	91	5	against	against	IN
cord-016903-z2vqfq98	91	6	invasive	invasive	JJ
cord-016903-z2vqfq98	91	7	pneumococcal	pneumococcal	JJ
cord-016903-z2vqfq98	91	8	disease	disease	NN
cord-016903-z2vqfq98	91	9	in	in	IN
cord-016903-z2vqfq98	91	10	65	65	CD
cord-016903-z2vqfq98	91	11	%	%	NN
cord-016903-z2vqfq98	91	12	of	of	IN
cord-016903-z2vqfq98	91	13	the	the	DT
cord-016903-z2vqfq98	91	14	general	general	JJ
cord-016903-z2vqfq98	91	15	elderly	elderly	JJ
cord-016903-z2vqfq98	91	16	population	population	NN
cord-016903-z2vqfq98	91	17	22.23whereas	22.23whereas	CD
cord-016903-z2vqfq98	91	18	in	in	IN
cord-016903-z2vqfq98	91	19	elderly	elderly	JJ
cord-016903-z2vqfq98	91	20	persons	person	NNS
cord-016903-z2vqfq98	91	21	with	with	IN
cord-016903-z2vqfq98	91	22	high	high	JJ
cord-016903-z2vqfq98	91	23	risk	risk	NN
cord-016903-z2vqfq98	91	24	factors	factor	NNS
cord-016903-z2vqfq98	91	25	,	,	,
cord-016903-z2vqfq98	91	26	the	the	DT
cord-016903-z2vqfq98	91	27	protective	protective	JJ
cord-016903-z2vqfq98	91	28	effect	effect	NN
cord-016903-z2vqfq98	91	29	of	of	IN
cord-016903-z2vqfq98	91	30	vaccination	vaccination	NN
cord-016903-z2vqfq98	91	31	seems	seem	VBZ
cord-016903-z2vqfq98	91	32	to	to	TO
cord-016903-z2vqfq98	91	33	be	be	VB
cord-016903-z2vqfq98	91	34	only	only	RB
cord-016903-z2vqfq98	91	35	moderate	moderate	JJ
cord-016903-z2vqfq98	91	36	.	.	.
cord-016903-z2vqfq98	92	1	Although	although	IN
cord-016903-z2vqfq98	92	2	many	many	JJ
cord-016903-z2vqfq98	92	3	European	european	JJ
cord-016903-z2vqfq98	92	4	countries	country	NNS
cord-016903-z2vqfq98	92	5	recommend	recommend	VBP
cord-016903-z2vqfq98	92	6	the	the	DT
cord-016903-z2vqfq98	92	7	administration	administration	NN
cord-016903-z2vqfq98	92	8	of	of	IN
cord-016903-z2vqfq98	92	9	pneumococcal	pneumococcal	JJ
cord-016903-z2vqfq98	92	10	vaccines	vaccine	NNS
cord-016903-z2vqfq98	92	11	to	to	IN
cord-016903-z2vqfq98	92	12	all	all	PDT
cord-016903-z2vqfq98	92	13	those	those	DT
cord-016903-z2vqfq98	92	14	>	>	XX
cord-016903-z2vqfq98	92	15	65	65	CD
cord-016903-z2vqfq98	92	16	years	year	NNS
cord-016903-z2vqfq98	92	17	ofage	ofage	JJ
cord-016903-z2vqfq98	92	18	,	,	,
cord-016903-z2vqfq98	92	19	vaccination	vaccination	NN
cord-016903-z2vqfq98	92	20	coverage	coverage	NN
cord-016903-z2vqfq98	92	21	among	among	IN
cord-016903-z2vqfq98	92	22	the	the	DT
cord-016903-z2vqfq98	92	23	elderly	elderly	JJ
cord-016903-z2vqfq98	92	24	population	population	NN
cord-016903-z2vqfq98	92	25	is	be	VBZ
cord-016903-z2vqfq98	92	26	very	very	RB
cord-016903-z2vqfq98	92	27	low	low	JJ
cord-016903-z2vqfq98	92	28	.	.	.
cord-016903-z2vqfq98	93	1	This	this	DT
cord-016903-z2vqfq98	93	2	may	may	MD
cord-016903-z2vqfq98	93	3	be	be	VB
cord-016903-z2vqfq98	93	4	due	due	JJ
cord-016903-z2vqfq98	93	5	to	to	IN
cord-016903-z2vqfq98	93	6	the	the	DT
cord-016903-z2vqfq98	93	7	high	high	JJ
cord-016903-z2vqfq98	93	8	costs	cost	NNS
cord-016903-z2vqfq98	93	9	ofthe	ofthe	DT
cord-016903-z2vqfq98	93	10	vaccine	vaccine	NN
cord-016903-z2vqfq98	93	11	and	and	CC
cord-016903-z2vqfq98	93	12	its	-PRON-	PRP$
cord-016903-z2vqfq98	93	13	unsatisfying	unsatisfying	JJ
cord-016903-z2vqfq98	93	14	efficacy	efficacy	NN
cord-016903-z2vqfq98	93	15	in	in	IN
cord-016903-z2vqfq98	93	16	elderly	elderly	JJ
cord-016903-z2vqfq98	93	17	people	people	NNS
cord-016903-z2vqfq98	93	18	.	.	.
cord-016903-z2vqfq98	94	1	But	but	CC
cord-016903-z2vqfq98	94	2	more	more	RBR
cord-016903-z2vqfq98	94	3	immunogenic	immunogenic	JJ
cord-016903-z2vqfq98	94	4	vaccines	vaccine	NNS
cord-016903-z2vqfq98	94	5	are	be	VBP
cord-016903-z2vqfq98	94	6	currently	currently	RB
cord-016903-z2vqfq98	94	7	in	in	IN
cord-016903-z2vqfq98	94	8	different	different	JJ
cord-016903-z2vqfq98	94	9	phases	phase	NNS
cord-016903-z2vqfq98	94	10	ofclinical	ofclinical	JJ
cord-016903-z2vqfq98	94	11	trials	trial	NNS
cord-016903-z2vqfq98	94	12	(	(	-LRB-
cord-016903-z2vqfq98	94	13	Table	Table	NNP
cord-016903-z2vqfq98	94	14	1	1	CD
cord-016903-z2vqfq98	94	15	)	)	-RRB-
cord-016903-z2vqfq98	94	16	and	and	CC
cord-016903-z2vqfq98	94	17	promise	promise	VBP
cord-016903-z2vqfq98	94	18	to	to	TO
cord-016903-z2vqfq98	94	19	be	be	VB
cord-016903-z2vqfq98	94	20	more	more	RBR
cord-016903-z2vqfq98	94	21	efficient	efficient	JJ
cord-016903-z2vqfq98	94	22	in	in	IN
cord-016903-z2vqfq98	94	23	old	old	JJ
cord-016903-z2vqfq98	94	24	age	age	NN
cord-016903-z2vqfq98	94	25	.	.	.
cord-016903-z2vqfq98	95	1	Additionally	additionally	RB
cord-016903-z2vqfq98	95	2	,	,	,
cord-016903-z2vqfq98	95	3	implementing	implement	VBG
cord-016903-z2vqfq98	95	4	pneumococcal	pneumococcal	JJ
cord-016903-z2vqfq98	95	5	vaccination	vaccination	NN
cord-016903-z2vqfq98	95	6	for	for	IN
cord-016903-z2vqfq98	95	7	children	child	NNS
cord-016903-z2vqfq98	95	8	may	may	MD
cord-016903-z2vqfq98	95	9	decrease	decrease	VB
cord-016903-z2vqfq98	95	10	the	the	DT
cord-016903-z2vqfq98	95	11	incidence	incidence	NN
cord-016903-z2vqfq98	95	12	ofpneumococcal	ofpneumococcal	JJ
cord-016903-z2vqfq98	95	13	disease	disease	NN
cord-016903-z2vqfq98	95	14	in	in	IN
cord-016903-z2vqfq98	95	15	the	the	DT
cord-016903-z2vqfq98	95	16	elderly	elderly	JJ
cord-016903-z2vqfq98	95	17	by	by	IN
cord-016903-z2vqfq98	95	18	reducing	reduce	VBG
cord-016903-z2vqfq98	95	19	transmission	transmission	NN
cord-016903-z2vqfq98	95	20	and	and	CC
cord-016903-z2vqfq98	95	21	possibly	possibly	RB
cord-016903-z2vqfq98	95	22	accomplishing	accomplish	VBG
cord-016903-z2vqfq98	95	23	herd	herd	NN
cord-016903-z2vqfq98	96	1	immunity.-	immunity.-	NNP
cord-016903-z2vqfq98	96	2	"	"	``
cord-016903-z2vqfq98	96	3	Each	each	DT
cord-016903-z2vqfq98	96	4	year	year	NN
cord-016903-z2vqfq98	96	5	,	,	,
cord-016903-z2vqfq98	96	6	about	about	RB
cord-016903-z2vqfq98	96	7	8	8	CD
cord-016903-z2vqfq98	96	8	million	million	CD
cord-016903-z2vqfq98	96	9	people	people	NNS
cord-016903-z2vqfq98	96	10	are	be	VBP
cord-016903-z2vqfq98	96	11	infected	infect	VBN
cord-016903-z2vqfq98	96	12	worldwide	worldwide	RB
cord-016903-z2vqfq98	96	13	with	with	IN
cord-016903-z2vqfq98	96	14	the	the	DT
cord-016903-z2vqfq98	96	15	tubercle	tubercle	NN
cord-016903-z2vqfq98	96	16	bacillus	bacillus	NN
cord-016903-z2vqfq98	96	17	Mycobacterium	Mycobacterium	NNP
cord-016903-z2vqfq98	96	18	tuberculosis	tuberculosis	NN
cord-016903-z2vqfq98	96	19	and	and	CC
cord-016903-z2vqfq98	96	20	1.6	1.6	CD
cord-016903-z2vqfq98	96	21	million	million	CD
cord-016903-z2vqfq98	96	22	ofthem	ofthem	NNS
cord-016903-z2vqfq98	96	23	die	die	VBP
cord-016903-z2vqfq98	96	24	.	.	.
cord-016903-z2vqfq98	97	1	The	the	DT
cord-016903-z2vqfq98	97	2	EU25	EU25	NNP
cord-016903-z2vqfq98	97	3	has	have	VBZ
cord-016903-z2vqfq98	97	4	a	a	DT
cord-016903-z2vqfq98	97	5	tuberculosis	tuberculosis	NN
cord-016903-z2vqfq98	97	6	(	(	-LRB-
cord-016903-z2vqfq98	97	7	TB	TB	NNP
cord-016903-z2vqfq98	97	8	)	)	-RRB-
cord-016903-z2vqfq98	97	9	burden	burden	NN
cord-016903-z2vqfq98	97	10	ofmore	ofmore	JJR
cord-016903-z2vqfq98	97	11	than50,000	than50,000	CD
cord-016903-z2vqfq98	97	12	new	new	JJ
cord-016903-z2vqfq98	97	13	casesper	casesper	NN
cord-016903-z2vqfq98	97	14	year	year	NN
cord-016903-z2vqfq98	97	15	,	,	,
cord-016903-z2vqfq98	97	16	with	with	IN
cord-016903-z2vqfq98	97	17	the	the	DT
cord-016903-z2vqfq98	97	18	highest	high	JJS
cord-016903-z2vqfq98	97	19	incidences	incidence	NNS
cord-016903-z2vqfq98	97	20	in	in	IN
cord-016903-z2vqfq98	97	21	Latvia	Latvia	NNP
cord-016903-z2vqfq98	97	22	,	,	,
cord-016903-z2vqfq98	97	23	Lithuania	Lithuania	NNP
cord-016903-z2vqfq98	97	24	and	and	CC
cord-016903-z2vqfq98	97	25	Estonia	Estonia	NNP
cord-016903-z2vqfq98	97	26	(	(	-LRB-
cord-016903-z2vqfq98	97	27	50	50	CD
cord-016903-z2vqfq98	97	28	-	-	SYM
cord-016903-z2vqfq98	97	29	100	100	CD
cord-016903-z2vqfq98	97	30	cases/	cases/	CD
cord-016903-z2vqfq98	97	31	100,000	100,000	CD
cord-016903-z2vqfq98	97	32	)	)	-RRB-
cord-016903-z2vqfq98	97	33	.	.	.
cord-016903-z2vqfq98	98	1	The	the	DT
cord-016903-z2vqfq98	98	2	risk	risk	NN
cord-016903-z2vqfq98	98	3	ofdeveloping	ofdevelope	VBG
cord-016903-z2vqfq98	98	4	a	a	DT
cord-016903-z2vqfq98	98	5	disease	disease	NN
cord-016903-z2vqfq98	98	6	following	follow	VBG
cord-016903-z2vqfq98	98	7	TB	TB	NNP
cord-016903-z2vqfq98	98	8	infection	infection	NN
cord-016903-z2vqfq98	98	9	is	be	VBZ
cord-016903-z2vqfq98	98	10	about	about	RB
cord-016903-z2vqfq98	98	11	5	5	CD
cord-016903-z2vqfq98	98	12	-	-	SYM
cord-016903-z2vqfq98	98	13	10	10	CD
cord-016903-z2vqfq98	98	14	%	%	NN
cord-016903-z2vqfq98	98	15	during	during	IN
cord-016903-z2vqfq98	98	16	lifetime	lifetime	NN
cord-016903-z2vqfq98	98	17	and	and	CC
cord-016903-z2vqfq98	98	18	individuals	individual	NNS
cord-016903-z2vqfq98	98	19	above	above	IN
cord-016903-z2vqfq98	98	20	65	65	CD
cord-016903-z2vqfq98	98	21	years	year	NNS
cord-016903-z2vqfq98	98	22	ofage	ofage	RB
cord-016903-z2vqfq98	98	23	have	have	VBP
cord-016903-z2vqfq98	98	24	a	a	DT
cord-016903-z2vqfq98	98	25	four	four	CD
cord-016903-z2vqfq98	98	26	-	-	HYPH
cord-016903-z2vqfq98	98	27	fold	fold	JJ
cord-016903-z2vqfq98	98	28	increased	increased	JJ
cord-016903-z2vqfq98	98	29	risk	risk	NN
cord-016903-z2vqfq98	98	30	ofdeveloping	ofdevelope	VBG
cord-016903-z2vqfq98	98	31	TB	TB	NNP
cord-016903-z2vqfq98	98	32	than	than	IN
cord-016903-z2vqfq98	98	33	the	the	DT
cord-016903-z2vqfq98	98	34	average	average	JJ
cord-016903-z2vqfq98	98	35	population	population	NN
cord-016903-z2vqfq98	98	36	,	,	,
cord-016903-z2vqfq98	98	37	"	"	''
cord-016903-z2vqfq98	98	38	TB	TB	NNP
cord-016903-z2vqfq98	98	39	is	be	VBZ
cord-016903-z2vqfq98	98	40	also	also	RB
cord-016903-z2vqfq98	98	41	frequently	frequently	RB
cord-016903-z2vqfq98	98	42	diagnosed	diagnose	VBN
cord-016903-z2vqfq98	98	43	with	with	IN
cord-016903-z2vqfq98	98	44	delay	delay	NN
cord-016903-z2vqfq98	98	45	due	due	IN
cord-016903-z2vqfq98	98	46	to	to	IN
cord-016903-z2vqfq98	98	47	an	an	DT
cord-016903-z2vqfq98	98	48	atypical	atypical	JJ
cord-016903-z2vqfq98	98	49	manifestation	manifestation	NN
cord-016903-z2vqfq98	98	50	in	in	IN
cord-016903-z2vqfq98	98	51	old	old	JJ
cord-016903-z2vqfq98	98	52	age	age	NN
cord-016903-z2vqfq98	98	53	.	.	.
cord-016903-z2vqfq98	99	1	This	this	DT
cord-016903-z2vqfq98	99	2	may	may	MD
cord-016903-z2vqfq98	99	3	lead	lead	VB
cord-016903-z2vqfq98	99	4	to	to	IN
cord-016903-z2vqfq98	99	5	an	an	DT
cord-016903-z2vqfq98	99	6	increased	increase	VBN
cord-016903-z2vqfq98	99	7	morbidity	morbidity	NN
cord-016903-z2vqfq98	99	8	and	and	CC
cord-016903-z2vqfq98	99	9	mortality	mortality	NN
cord-016903-z2vqfq98	99	10	and	and	CC
cord-016903-z2vqfq98	99	11	to	to	IN
cord-016903-z2vqfq98	99	12	a	a	DT
cord-016903-z2vqfq98	99	13	spreading	spread	VBG
cord-016903-z2vqfq98	99	14	ofthe	ofthe	DT
cord-016903-z2vqfq98	99	15	disease	disease	NN
cord-016903-z2vqfq98	99	16	,	,	,
cord-016903-z2vqfq98	99	17	in	in	IN
cord-016903-z2vqfq98	99	18	particular	particular	JJ
cord-016903-z2vqfq98	99	19	within	within	IN
cord-016903-z2vqfq98	99	20	institutionalized	institutionalized	JJ
cord-016903-z2vqfq98	99	21	elderly	elderly	JJ
cord-016903-z2vqfq98	99	22	persons	person	NNS
cord-016903-z2vqfq98	99	23	.	.	.
cord-016903-z2vqfq98	100	1	P	p	NN
cord-016903-z2vqfq98	100	2	Further	further	JJ
cord-016903-z2vqfq98	100	3	difficulties	difficulty	NNS
cord-016903-z2vqfq98	100	4	include	include	VBP
cord-016903-z2vqfq98	100	5	the	the	DT
cord-016903-z2vqfq98	100	6	increased	increase	VBN
cord-016903-z2vqfq98	100	7	emergence	emergence	NN
cord-016903-z2vqfq98	100	8	of	of	IN
cord-016903-z2vqfq98	100	9	new	new	JJ
cord-016903-z2vqfq98	100	10	,	,	,
cord-016903-z2vqfq98	100	11	multiple	multiple	JJ
cord-016903-z2vqfq98	100	12	drug	drug	NN
cord-016903-z2vqfq98	100	13	-	-	HYPH
cord-016903-z2vqfq98	100	14	resistant	resistant	JJ
cord-016903-z2vqfq98	100	15	strains	strain	NNS
cord-016903-z2vqfq98	100	16	with	with	IN
cord-016903-z2vqfq98	100	17	higher	high	JJR
cord-016903-z2vqfq98	100	18	rransmissibiliry	rransmissibiliry	NN
cord-016903-z2vqfq98	100	19	,	,	,
cord-016903-z2vqfq98	100	20	"	"	''
cord-016903-z2vqfq98	100	21	the	the	DT
cord-016903-z2vqfq98	100	22	poor	poor	JJ
cord-016903-z2vqfq98	100	23	efficacy	efficacy	NN
cord-016903-z2vqfq98	100	24	of	of	IN
cord-016903-z2vqfq98	100	25	the	the	DT
cord-016903-z2vqfq98	100	26	current	current	JJ
cord-016903-z2vqfq98	100	27	bacille	bacille	NN
cord-016903-z2vqfq98	100	28	Calmette	Calmette	NNP
cord-016903-z2vqfq98	100	29	Guerin	Guerin	NNP
cord-016903-z2vqfq98	100	30	(	(	-LRB-
cord-016903-z2vqfq98	100	31	BCG	BCG	NNP
cord-016903-z2vqfq98	100	32	)	)	-RRB-
cord-016903-z2vqfq98	100	33	vaccine	vaccine	NN
cord-016903-z2vqfq98	100	34	in	in	IN
cord-016903-z2vqfq98	100	35	protecting	protect	VBG
cord-016903-z2vqfq98	100	36	adults	adult	NNS
cord-016903-z2vqfq98	100	37	and	and	CC
cord-016903-z2vqfq98	100	38	elderly	elderly	JJ
cord-016903-z2vqfq98	100	39	people	people	NNS
cord-016903-z2vqfq98	100	40	from	from	IN
cord-016903-z2vqfq98	100	41	pulmonary	pulmonary	JJ
cord-016903-z2vqfq98	100	42	Infection	infection	NN
cord-016903-z2vqfq98	100	43	"	"	''
cord-016903-z2vqfq98	100	44	and	and	CC
cord-016903-z2vqfq98	100	45	the	the	DT
cord-016903-z2vqfq98	100	46	increased	increase	VBN
cord-016903-z2vqfq98	100	47	risk	risk	NN
cord-016903-z2vqfq98	100	48	ofTB	ofTB	NNP
cord-016903-z2vqfq98	100	49	co	co	NN
cord-016903-z2vqfq98	100	50	-	-	NN
cord-016903-z2vqfq98	100	51	infection	infection	NN
cord-016903-z2vqfq98	100	52	in	in	IN
cord-016903-z2vqfq98	100	53	HIV	HIV	NNP
cord-016903-z2vqfq98	100	54	positive	positive	JJ
cord-016903-z2vqfq98	100	55	patients	patient	NNS
cord-016903-z2vqfq98	100	56	.	.	.
cord-016903-z2vqfq98	100	57	"	"	''
cord-016903-z2vqfq98	101	1	However	however	RB
cord-016903-z2vqfq98	101	2	,	,	,
cord-016903-z2vqfq98	101	3	in	in	IN
cord-016903-z2vqfq98	101	4	the	the	DT
cord-016903-z2vqfq98	101	5	past	past	JJ
cord-016903-z2vqfq98	101	6	few	few	JJ
cord-016903-z2vqfq98	101	7	years	year	NNS
cord-016903-z2vqfq98	101	8	,	,	,
cord-016903-z2vqfq98	101	9	several	several	JJ
cord-016903-z2vqfq98	101	10	TB	TB	NNP
cord-016903-z2vqfq98	101	11	vaccine	vaccine	NN
cord-016903-z2vqfq98	101	12	candidates	candidate	NNS
cord-016903-z2vqfq98	101	13	have	have	VBP
cord-016903-z2vqfq98	101	14	entered	enter	VBN
cord-016903-z2vqfq98	101	15	phase	phase	NN
cord-016903-z2vqfq98	102	1	I	-PRON-	PRP
cord-016903-z2vqfq98	102	2	clinical	clinical	JJ
cord-016903-z2vqfq98	102	3	trials	trial	NNS
cord-016903-z2vqfq98	102	4	,	,	,
cord-016903-z2vqfq98	102	5	including	include	VBG
cord-016903-z2vqfq98	102	6	adjuvanted	adjuvante	VBN
cord-016903-z2vqfq98	102	7	subunit	subunit	NN
cord-016903-z2vqfq98	102	8	vaccines	vaccine	NNS
cord-016903-z2vqfq98	102	9	as	as	RB
cord-016903-z2vqfq98	102	10	well	well	RB
cord-016903-z2vqfq98	102	11	as	as	IN
cord-016903-z2vqfq98	102	12	improved	improve	VBN
cord-016903-z2vqfq98	102	13	live	live	JJ
cord-016903-z2vqfq98	102	14	recombinant	recombinant	JJ
cord-016903-z2vqfq98	102	15	strains	strain	NNS
cord-016903-z2vqfq98	102	16	of	of	IN
cord-016903-z2vqfq98	102	17	the	the	DT
cord-016903-z2vqfq98	102	18	current	current	JJ
cord-016903-z2vqfq98	102	19	BCG	BCG	NNP
cord-016903-z2vqfq98	102	20	vaccine	vaccine	NN
cord-016903-z2vqfq98	102	21	(	(	-LRB-
cord-016903-z2vqfq98	102	22	Table	table	NN
cord-016903-z2vqfq98	102	23	1	1	CD
cord-016903-z2vqfq98	102	24	)	)	-RRB-
cord-016903-z2vqfq98	102	25	.	.	.
cord-016903-z2vqfq98	103	1	All	all	PDT
cord-016903-z2vqfq98	103	2	these	these	DT
cord-016903-z2vqfq98	103	3	vaccine	vaccine	NN
cord-016903-z2vqfq98	103	4	candidates	candidate	NNS
cord-016903-z2vqfq98	103	5	are	be	VBP
cord-016903-z2vqfq98	103	6	supposed	suppose	VBN
cord-016903-z2vqfq98	103	7	to	to	TO
cord-016903-z2vqfq98	103	8	induce	induce	VB
cord-016903-z2vqfq98	103	9	an	an	DT
cord-016903-z2vqfq98	103	10	effective	effective	JJ
cord-016903-z2vqfq98	103	11	and	and	CC
cord-016903-z2vqfq98	103	12	sustainable	sustainable	JJ
cord-016903-z2vqfq98	103	13	cellular	cellular	JJ
cord-016903-z2vqfq98	103	14	immune	immune	JJ
cord-016903-z2vqfq98	103	15	response	response	NN
cord-016903-z2vqfq98	103	16	which	which	WDT
cord-016903-z2vqfq98	103	17	is	be	VBZ
cord-016903-z2vqfq98	103	18	thought	think	VBN
cord-016903-z2vqfq98	103	19	to	to	TO
cord-016903-z2vqfq98	103	20	be	be	VB
cord-016903-z2vqfq98	103	21	crucial	crucial	JJ
cord-016903-z2vqfq98	103	22	to	to	TO
cord-016903-z2vqfq98	103	23	protect	protect	VB
cord-016903-z2vqfq98	103	24	the	the	DT
cord-016903-z2vqfq98	103	25	host	host	NN
cord-016903-z2vqfq98	103	26	from	from	IN
cord-016903-z2vqfq98	103	27	an	an	DT
cord-016903-z2vqfq98	103	28	intracellular	intracellular	JJ
cord-016903-z2vqfq98	103	29	pathogen	pathogen	NN
cord-016903-z2vqfq98	103	30	such	such	JJ
cord-016903-z2vqfq98	103	31	as	as	IN
cord-016903-z2vqfq98	103	32	Mycobacterium	Mycobacterium	NNP
cord-016903-z2vqfq98	103	33	tuberculosis	tuberculosis	NN
cord-016903-z2vqfq98	103	34	.	.	.
cord-016903-z2vqfq98	104	1	30	30	CD
cord-016903-z2vqfq98	104	2	 	 	_SP
cord-016903-z2vqfq98	104	3	Primary	primary	JJ
cord-016903-z2vqfq98	104	4	infection	infection	NN
cord-016903-z2vqfq98	104	5	with	with	IN
cord-016903-z2vqfq98	104	6	the	the	DT
cord-016903-z2vqfq98	104	7	Varicella	Varicella	NNP
cord-016903-z2vqfq98	104	8	zoster	zoster	NN
cord-016903-z2vqfq98	104	9	virus	virus	NN
cord-016903-z2vqfq98	104	10	(	(	-LRB-
cord-016903-z2vqfq98	104	11	VZV	VZV	NNP
cord-016903-z2vqfq98	104	12	)	)	-RRB-
cord-016903-z2vqfq98	104	13	causes	cause	VBZ
cord-016903-z2vqfq98	104	14	chickenpox	chickenpox	NN
cord-016903-z2vqfq98	104	15	which	which	WDT
cord-016903-z2vqfq98	104	16	is	be	VBZ
cord-016903-z2vqfq98	104	17	usually	usually	RB
cord-016903-z2vqfq98	104	18	a	a	DT
cord-016903-z2vqfq98	104	19	mild	mild	JJ
cord-016903-z2vqfq98	104	20	disease	disease	NN
cord-016903-z2vqfq98	104	21	in	in	IN
cord-016903-z2vqfq98	104	22	childhood	childhood	NN
cord-016903-z2vqfq98	104	23	.	.	.
cord-016903-z2vqfq98	105	1	The	the	DT
cord-016903-z2vqfq98	105	2	virus	virus	NN
cord-016903-z2vqfq98	105	3	then	then	RB
cord-016903-z2vqfq98	105	4	persists	persist	VBZ
cord-016903-z2vqfq98	105	5	in	in	IN
cord-016903-z2vqfq98	105	6	a	a	DT
cord-016903-z2vqfq98	105	7	latent	latent	JJ
cord-016903-z2vqfq98	105	8	form	form	NN
cord-016903-z2vqfq98	105	9	in	in	IN
cord-016903-z2vqfq98	105	10	sensory	sensory	JJ
cord-016903-z2vqfq98	105	11	ganglia	ganglion	NNS
cord-016903-z2vqfq98	105	12	until	until	IN
cord-016903-z2vqfq98	105	13	its	-PRON-	PRP$
cord-016903-z2vqfq98	105	14	reactivation	reactivation	NN
cord-016903-z2vqfq98	105	15	which	which	WDT
cord-016903-z2vqfq98	105	16	results	result	VBZ
cord-016903-z2vqfq98	105	17	in	in	IN
cord-016903-z2vqfq98	105	18	the	the	DT
cord-016903-z2vqfq98	105	19	clinical	clinical	JJ
cord-016903-z2vqfq98	105	20	manifestation	manifestation	NN
cord-016903-z2vqfq98	105	21	of	of	IN
cord-016903-z2vqfq98	105	22	herpes	herpes	NNP
cord-016903-z2vqfq98	105	23	zoster	zoster	NN
cord-016903-z2vqfq98	105	24	(	(	-LRB-
cord-016903-z2vqfq98	105	25	shingles	shingle	NNS
cord-016903-z2vqfq98	105	26	)	)	-RRB-
cord-016903-z2vqfq98	105	27	.	.	.
cord-016903-z2vqfq98	106	1	Between	between	IN
cord-016903-z2vqfq98	106	2	13	13	CD
cord-016903-z2vqfq98	106	3	and	and	CC
cord-016903-z2vqfq98	106	4	26	26	CD
cord-016903-z2vqfq98	106	5	%	%	NN
cord-016903-z2vqfq98	106	6	ofpersons	ofperson	NNS
cord-016903-z2vqfq98	106	7	with	with	IN
cord-016903-z2vqfq98	106	8	herpes	herpes	NN
cord-016903-z2vqfq98	106	9	zoster	zoster	NN
cord-016903-z2vqfq98	106	10	develop	develop	VBP
cord-016903-z2vqfq98	106	11	complications	complication	NNS
cord-016903-z2vqfq98	106	12	,	,	,
cord-016903-z2vqfq98	106	13	such	such	JJ
cord-016903-z2vqfq98	106	14	as	as	IN
cord-016903-z2vqfq98	106	15	postherpetic	postherpetic	NNP
cord-016903-z2vqfq98	106	16	neuralgia	neuralgia	NNP
cord-016903-z2vqfq98	106	17	.	.	.
cord-016903-z2vqfq98	107	1	"	"	''
cord-016903-z2vqfq98	108	1	Postherpetic	Postherpetic	NNP
cord-016903-z2vqfq98	108	2	neuralgia	neuralgia	NN
cord-016903-z2vqfq98	108	3	also	also	RB
cord-016903-z2vqfq98	108	4	increases	increase	VBZ
cord-016903-z2vqfq98	108	5	with	with	IN
cord-016903-z2vqfq98	108	6	age	age	NN
cord-016903-z2vqfq98	108	7	with	with	IN
cord-016903-z2vqfq98	108	8	a	a	DT
cord-016903-z2vqfq98	108	9	prevalence	prevalence	NN
cord-016903-z2vqfq98	108	10	of	of	IN
cord-016903-z2vqfq98	108	11	50	50	CD
cord-016903-z2vqfq98	108	12	%	%	NN
cord-016903-z2vqfq98	108	13	in	in	IN
cord-016903-z2vqfq98	108	14	people	people	NNS
cord-016903-z2vqfq98	108	15	aged	age	VBN
cord-016903-z2vqfq98	108	16	70	70	CD
cord-016903-z2vqfq98	108	17	years	year	NNS
cord-016903-z2vqfq98	108	18	and	and	CC
cord-016903-z2vqfq98	108	19	above	above	RB
cord-016903-z2vqfq98	108	20	.	.	.
cord-016903-z2vqfq98	109	1	The	the	DT
cord-016903-z2vqfq98	109	2	incidence	incidence	NN
cord-016903-z2vqfq98	109	3	and	and	CC
cord-016903-z2vqfq98	109	4	severity	severity	NN
cord-016903-z2vqfq98	109	5	ofherpes	ofherpes	IN
cord-016903-z2vqfq98	109	6	zoster	zoster	NN
cord-016903-z2vqfq98	109	7	increase	increase	VBP
cord-016903-z2vqfq98	109	8	with	with	IN
cord-016903-z2vqfq98	109	9	age	age	NN
cord-016903-z2vqfq98	109	10	,	,	,
cord-016903-z2vqfq98	109	11	because	because	IN
cord-016903-z2vqfq98	109	12	VZV	VZV	NNP
cord-016903-z2vqfq98	109	13	reactivation	reactivation	NN
cord-016903-z2vqfq98	109	14	is	be	VBZ
cord-016903-z2vqfq98	109	15	associated	associate	VBN
cord-016903-z2vqfq98	109	16	with	with	IN
cord-016903-z2vqfq98	109	17	a	a	DT
cord-016903-z2vqfq98	109	18	progressive	progressive	JJ
cord-016903-z2vqfq98	109	19	decline	decline	NN
cord-016903-z2vqfq98	109	20	in	in	IN
cord-016903-z2vqfq98	109	21	cell	cell	NN
cord-016903-z2vqfq98	109	22	-	-	HYPH
cord-016903-z2vqfq98	109	23	mediated	mediate	VBN
cord-016903-z2vqfq98	109	24	immunity	immunity	NN
cord-016903-z2vqfq98	109	25	to	to	IN
cord-016903-z2vqfq98	109	26	VZVY.·33	VZVY.·33	NNP
cord-016903-z2vqfq98	109	27	Routine	routine	JJ
cord-016903-z2vqfq98	109	28	vaccination	vaccination	NN
cord-016903-z2vqfq98	109	29	ofchildren	ofchildren	NN
cord-016903-z2vqfq98	109	30	using	use	VBG
cord-016903-z2vqfq98	109	31	a	a	DT
cord-016903-z2vqfq98	109	32	tetravalent	tetravalent	NN
cord-016903-z2vqfq98	109	33	vaccine	vaccine	NN
cord-016903-z2vqfq98	109	34	that	that	WDT
cord-016903-z2vqfq98	109	35	protects	protect	VBZ
cord-016903-z2vqfq98	109	36	against	against	IN
cord-016903-z2vqfq98	109	37	measles	measle	NNS
cord-016903-z2vqfq98	109	38	,	,	,
cord-016903-z2vqfq98	109	39	mumps	mumps	NN
cord-016903-z2vqfq98	109	40	,	,	,
cord-016903-z2vqfq98	109	41	rubella	rubella	NN
cord-016903-z2vqfq98	109	42	and	and	CC
cord-016903-z2vqfq98	109	43	varicella	varicella	NN
cord-016903-z2vqfq98	109	44	will	will	MD
cord-016903-z2vqfq98	109	45	soon	soon	RB
cord-016903-z2vqfq98	109	46	be	be	VB
cord-016903-z2vqfq98	109	47	available	available	JJ
cord-016903-z2vqfq98	109	48	(	(	-LRB-
cord-016903-z2vqfq98	109	49	Table	table	NN
cord-016903-z2vqfq98	109	50	1	1	CD
cord-016903-z2vqfq98	109	51	)	)	-RRB-
cord-016903-z2vqfq98	109	52	and	and	CC
cord-016903-z2vqfq98	109	53	may	may	MD
cord-016903-z2vqfq98	109	54	reduce	reduce	VB
cord-016903-z2vqfq98	109	55	the	the	DT
cord-016903-z2vqfq98	109	56	incidence	incidence	NN
cord-016903-z2vqfq98	109	57	of	of	IN
cord-016903-z2vqfq98	109	58	chickenpox	chickenpox	NN
cord-016903-z2vqfq98	109	59	as	as	RB
cord-016903-z2vqfq98	109	60	well	well	RB
cord-016903-z2vqfq98	109	61	as	as	IN
cord-016903-z2vqfq98	109	62	the	the	DT
cord-016903-z2vqfq98	109	63	reactivation	reactivation	NN
cord-016903-z2vqfq98	109	64	ofVZV	ofvzv	NN
cord-016903-z2vqfq98	110	1	in	in	IN
cord-016903-z2vqfq98	110	2	later	later	JJ
cord-016903-z2vqfq98	110	3	life	life	NN
cord-016903-z2vqfq98	110	4	.	.	.
cord-016903-z2vqfq98	111	1	Since	since	IN
cord-016903-z2vqfq98	111	2	1995	1995	CD
cord-016903-z2vqfq98	111	3	,	,	,
cord-016903-z2vqfq98	111	4	a	a	DT
cord-016903-z2vqfq98	111	5	live	live	RB
cord-016903-z2vqfq98	111	6	-	-	HYPH
cord-016903-z2vqfq98	111	7	attenuated	attenuated	JJ
cord-016903-z2vqfq98	111	8	Oka	Oka	NNP
cord-016903-z2vqfq98	111	9	strain	strain	NN
cord-016903-z2vqfq98	111	10	VZV	VZV	NNP
cord-016903-z2vqfq98	111	11	vaccine	vaccine	NN
cord-016903-z2vqfq98	111	12	is	be	VBZ
cord-016903-z2vqfq98	111	13	on	on	IN
cord-016903-z2vqfq98	111	14	the	the	DT
cord-016903-z2vqfq98	111	15	market	market	NN
cord-016903-z2vqfq98	111	16	that	that	WDT
cord-016903-z2vqfq98	111	17	has	have	VBZ
cord-016903-z2vqfq98	111	18	shown	show	VBN
cord-016903-z2vqfq98	111	19	clinical	clinical	JJ
cord-016903-z2vqfq98	111	20	efficacy	efficacy	NN
cord-016903-z2vqfq98	111	21	in	in	IN
cord-016903-z2vqfq98	111	22	preventing	prevent	VBG
cord-016903-z2vqfq98	111	23	children	child	NNS
cord-016903-z2vqfq98	111	24	from	from	IN
cord-016903-z2vqfq98	111	25	chickenpox	chickenpox	NN
cord-016903-z2vqfq98	111	26	.	.	.
cord-016903-z2vqfq98	111	27	"	"	''
cord-016903-z2vqfq98	112	1	However	however	RB
cord-016903-z2vqfq98	112	2	,	,	,
cord-016903-z2vqfq98	112	3	the	the	DT
cord-016903-z2vqfq98	112	4	currently	currently	RB
cord-016903-z2vqfq98	112	5	available	available	JJ
cord-016903-z2vqfq98	112	6	VZV	VZV	NNP
cord-016903-z2vqfq98	112	7	vaccines	vaccine	NNS
cord-016903-z2vqfq98	112	8	have	have	VBP
cord-016903-z2vqfq98	112	9	not	not	RB
cord-016903-z2vqfq98	112	10	been	be	VBN
cord-016903-z2vqfq98	112	11	proven	prove	VBN
cord-016903-z2vqfq98	112	12	to	to	TO
cord-016903-z2vqfq98	112	13	adequately	adequately	RB
cord-016903-z2vqfq98	112	14	boost	boost	VB
cord-016903-z2vqfq98	112	15	T	t	NN
cord-016903-z2vqfq98	112	16	-	-	HYPH
cord-016903-z2vqfq98	112	17	cell	cell	NN
cord-016903-z2vqfq98	112	18	responses	response	NNS
cord-016903-z2vqfq98	112	19	in	in	IN
cord-016903-z2vqfq98	112	20	older	old	JJR
cord-016903-z2vqfq98	112	21	adults	adult	NNS
cord-016903-z2vqfq98	112	22	and	and	CC
cord-016903-z2vqfq98	112	23	to	to	TO
cord-016903-z2vqfq98	112	24	prevent	prevent	VB
cord-016903-z2vqfq98	112	25	reactivation	reactivation	NN
cord-016903-z2vqfq98	112	26	ofherpes	ofherpes	IN
cord-016903-z2vqfq98	112	27	zoster	zoster	NN
cord-016903-z2vqfq98	112	28	.	.	.
cord-016903-z2vqfq98	113	1	Recently	recently	RB
cord-016903-z2vqfq98	113	2	,	,	,
cord-016903-z2vqfq98	113	3	a	a	DT
cord-016903-z2vqfq98	113	4	vaccine	vaccine	NN
cord-016903-z2vqfq98	113	5	that	that	WDT
cord-016903-z2vqfq98	113	6	may	may	MD
cord-016903-z2vqfq98	113	7	prevent	prevent	VB
cord-016903-z2vqfq98	113	8	herpes	herpes	NN
cord-016903-z2vqfq98	113	9	zoster	zoster	NN
cord-016903-z2vqfq98	113	10	virus	virus	NN
cord-016903-z2vqfq98	113	11	reactivation	reactivation	NN
cord-016903-z2vqfq98	113	12	has	have	VBZ
cord-016903-z2vqfq98	113	13	been	be	VBN
cord-016903-z2vqfq98	113	14	submitted	submit	VBN
cord-016903-z2vqfq98	113	15	for	for	IN
cord-016903-z2vqfq98	113	16	registration	registration	NN
cord-016903-z2vqfq98	113	17	.	.	.
cord-016903-z2vqfq98	114	1	This	this	DT
cord-016903-z2vqfq98	114	2	live	live	RB
cord-016903-z2vqfq98	114	3	-	-	HYPH
cord-016903-z2vqfq98	114	4	attenuated	attenuated	JJ
cord-016903-z2vqfq98	114	5	VZV	VZV	NNP
cord-016903-z2vqfq98	114	6	vaccine	vaccine	NN
cord-016903-z2vqfq98	114	7	has	have	VBZ
cord-016903-z2vqfq98	114	8	been	be	VBN
cord-016903-z2vqfq98	114	9	developed	develop	VBN
cord-016903-z2vqfq98	114	10	to	to	TO
cord-016903-z2vqfq98	114	11	prevent	prevent	VB
cord-016903-z2vqfq98	114	12	reactivation	reactivation	NN
cord-016903-z2vqfq98	114	13	of	of	IN
cord-016903-z2vqfq98	114	14	herpes	herpe	NNS
cord-016903-z2vqfq98	114	15	zoster	zoster	NNP
cord-016903-z2vqfq98	114	16	in	in	IN
cord-016903-z2vqfq98	114	17	the	the	DT
cord-016903-z2vqfq98	114	18	elderly.3s.36This	elderly.3s.36This	NNP
cord-016903-z2vqfq98	114	19	is	be	VBZ
cord-016903-z2vqfq98	114	20	of	of	IN
cord-016903-z2vqfq98	114	21	particular	particular	JJ
cord-016903-z2vqfq98	114	22	importance	importance	NN
cord-016903-z2vqfq98	114	23	,	,	,
cord-016903-z2vqfq98	114	24	because	because	IN
cord-016903-z2vqfq98	114	25	the	the	DT
cord-016903-z2vqfq98	114	26	elderly	elderly	JJ
cord-016903-z2vqfq98	114	27	population	population	NN
cord-016903-z2vqfq98	114	28	has	have	VBZ
cord-016903-z2vqfq98	114	29	not	not	RB
cord-016903-z2vqfq98	114	30	been	be	VBN
cord-016903-z2vqfq98	114	31	vaccinated	vaccinate	VBN
cord-016903-z2vqfq98	114	32	against	against	IN
cord-016903-z2vqfq98	114	33	but	but	CC
cord-016903-z2vqfq98	114	34	may	may	MD
cord-016903-z2vqfq98	114	35	have	have	VB
cord-016903-z2vqfq98	114	36	been	be	VBN
cord-016903-z2vqfq98	114	37	frequently	frequently	RB
cord-016903-z2vqfq98	114	38	infected	infect	VBN
cord-016903-z2vqfq98	114	39	by	by	IN
cord-016903-z2vqfq98	114	40	Vzv	Vzv	NNP
cord-016903-z2vqfq98	114	41	.	.	.
cord-016903-z2vqfq98	115	1	For	for	IN
cord-016903-z2vqfq98	115	2	instance	instance	NN
cord-016903-z2vqfq98	115	3	,	,	,
cord-016903-z2vqfq98	115	4	more	more	JJR
cord-016903-z2vqfq98	115	5	than	than	IN
cord-016903-z2vqfq98	115	6	90	90	CD
cord-016903-z2vqfq98	115	7	%	%	NN
cord-016903-z2vqfq98	115	8	ofadults	ofadult	NNS
cord-016903-z2vqfq98	115	9	in	in	IN
cord-016903-z2vqfq98	115	10	the	the	DT
cord-016903-z2vqfq98	115	11	United	United	NNP
cord-016903-z2vqfq98	115	12	States	States	NNP
cord-016903-z2vqfq98	115	13	have	have	VBP
cord-016903-z2vqfq98	115	14	had	have	VBN
cord-016903-z2vqfq98	115	15	chickenpox	chickenpox	NN
cord-016903-z2vqfq98	115	16	.	.	.
cord-016903-z2vqfq98	116	1	As	as	IN
cord-016903-z2vqfq98	116	2	a	a	DT
cord-016903-z2vqfq98	116	3	consequence	consequence	NN
cord-016903-z2vqfq98	116	4	,	,	,
cord-016903-z2vqfq98	116	5	it	-PRON-	PRP
cord-016903-z2vqfq98	116	6	is	be	VBZ
cord-016903-z2vqfq98	116	7	estimated	estimate	VBN
cord-016903-z2vqfq98	116	8	that	that	IN
cord-016903-z2vqfq98	116	9	up	up	IN
cord-016903-z2vqfq98	116	10	to	to	TO
cord-016903-z2vqfq98	116	11	800,000	800,000	CD
cord-016903-z2vqfq98	116	12	people	people	NNS
cord-016903-z2vqfq98	116	13	in	in	IN
cord-016903-z2vqfq98	116	14	the	the	DT
cord-016903-z2vqfq98	116	15	United	United	NNP
cord-016903-z2vqfq98	116	16	States	States	NNP
cord-016903-z2vqfq98	116	17	suffer	suffer	VBP
cord-016903-z2vqfq98	116	18	from	from	IN
cord-016903-z2vqfq98	116	19	shingles	shingle	NNS
cord-016903-z2vqfq98	116	20	each	each	DT
cord-016903-z2vqfq98	116	21	year	year	NN
cord-016903-z2vqfq98	116	22	and	and	CC
cord-016903-z2vqfq98	116	23	the	the	DT
cord-016903-z2vqfq98	116	24	incidence	incidence	NN
cord-016903-z2vqfq98	116	25	is	be	VBZ
cord-016903-z2vqfq98	116	26	expected	expect	VBN
cord-016903-z2vqfq98	116	27	to	to	TO
cord-016903-z2vqfq98	116	28	increase	increase	VB
cord-016903-z2vqfq98	116	29	as	as	IN
cord-016903-z2vqfq98	116	30	the	the	DT
cord-016903-z2vqfq98	116	31	population	population	NN
cord-016903-z2vqfq98	116	32	ages	age	NNS
cord-016903-z2vqfq98	116	33	.	.	.
cord-016903-z2vqfq98	117	1	Thus	thus	RB
cord-016903-z2vqfq98	117	2	,	,	,
cord-016903-z2vqfq98	117	3	reactivation	reactivation	NN
cord-016903-z2vqfq98	117	4	ofherpes	ofherpes	IN
cord-016903-z2vqfq98	117	5	zoster	zoster	NN
cord-016903-z2vqfq98	117	6	and	and	CC
cord-016903-z2vqfq98	117	7	its	-PRON-	PRP$
cord-016903-z2vqfq98	117	8	clinical	clinical	JJ
cord-016903-z2vqfq98	117	9	manifestations	manifestation	NNS
cord-016903-z2vqfq98	117	10	represents	represent	VBZ
cord-016903-z2vqfq98	117	11	a	a	DT
cord-016903-z2vqfq98	117	12	serious	serious	JJ
cord-016903-z2vqfq98	117	13	health	health	NN
cord-016903-z2vqfq98	117	14	burden	burden	NN
cord-016903-z2vqfq98	117	15	to	to	IN
cord-016903-z2vqfq98	117	16	the	the	DT
cord-016903-z2vqfq98	117	17	growing	grow	VBG
cord-016903-z2vqfq98	117	18	elderly	elderly	JJ
cord-016903-z2vqfq98	117	19	population	population	NN
cord-016903-z2vqfq98	117	20	and	and	CC
cord-016903-z2vqfq98	117	21	could	could	MD
cord-016903-z2vqfq98	117	22	be	be	VB
cord-016903-z2vqfq98	117	23	counteracted	counteract	VBN
cord-016903-z2vqfq98	117	24	by	by	IN
cord-016903-z2vqfq98	117	25	potent	potent	JJ
cord-016903-z2vqfq98	117	26	vaccines	vaccine	NNS
cord-016903-z2vqfq98	117	27	.	.	.
cord-016903-z2vqfq98	118	1	The	the	DT
cord-016903-z2vqfq98	118	2	cytomegalovirus	cytomegalovirus	NN
cord-016903-z2vqfq98	118	3	(	(	-LRB-
cord-016903-z2vqfq98	118	4	CMV	CMV	NNP
cord-016903-z2vqfq98	118	5	)	)	-RRB-
cord-016903-z2vqfq98	118	6	,	,	,
cord-016903-z2vqfq98	118	7	a	a	DT
cord-016903-z2vqfq98	118	8	B	b	NN
cord-016903-z2vqfq98	118	9	-	-	HYPH
cord-016903-z2vqfq98	118	10	herpesvirus	herpesvirus	NN
cord-016903-z2vqfq98	118	11	,	,	,
cord-016903-z2vqfq98	118	12	has	have	VBZ
cord-016903-z2vqfq98	118	13	also	also	RB
cord-016903-z2vqfq98	118	14	been	be	VBN
cord-016903-z2vqfq98	118	15	shown	show	VBN
cord-016903-z2vqfq98	118	16	to	to	TO
cord-016903-z2vqfq98	118	17	persist	persist	VB
cord-016903-z2vqfq98	118	18	throughout	throughout	IN
cord-016903-z2vqfq98	118	19	life	life	NN
cord-016903-z2vqfq98	118	20	until	until	IN
cord-016903-z2vqfq98	118	21	its	-PRON-	PRP$
cord-016903-z2vqfq98	118	22	reactivation	reactivation	NN
cord-016903-z2vqfq98	118	23	as	as	IN
cord-016903-z2vqfq98	118	24	a	a	DT
cord-016903-z2vqfq98	118	25	result	result	NN
cord-016903-z2vqfq98	118	26	ofimmune	ofimmune	NNP
cord-016903-z2vqfq98	118	27	suppression	suppression	NN
cord-016903-z2vqfq98	118	28	or	or	CC
cord-016903-z2vqfq98	118	29	deficiency	deficiency	NN
cord-016903-z2vqfq98	118	30	.	.	.
cord-016903-z2vqfq98	119	1	CMV	CMV	NNP
cord-016903-z2vqfq98	119	2	infection	infection	NN
cord-016903-z2vqfq98	119	3	is	be	VBZ
cord-016903-z2vqfq98	119	4	quite	quite	RB
cord-016903-z2vqfq98	119	5	common	common	JJ
cord-016903-z2vqfq98	119	6	and	and	CC
cord-016903-z2vqfq98	119	7	affects	affect	VBZ
cord-016903-z2vqfq98	119	8	60	60	CD
cord-016903-z2vqfq98	119	9	-	-	SYM
cord-016903-z2vqfq98	119	10	100	100	CD
cord-016903-z2vqfq98	119	11	%	%	NN
cord-016903-z2vqfq98	119	12	ofthe	ofthe	DT
cord-016903-z2vqfq98	119	13	adult	adult	NN
cord-016903-z2vqfq98	119	14	population	population	NN
cord-016903-z2vqfq98	119	15	,	,	,
cord-016903-z2vqfq98	119	16	dependingon	dependingon	NNP
cord-016903-z2vqfq98	119	17	the	the	DT
cord-016903-z2vqfq98	119	18	area	area	NN
cord-016903-z2vqfq98	119	19	.	.	.
cord-016903-z2vqfq98	120	1	The	the	DT
cord-016903-z2vqfq98	120	2	CMVis	CMVis	NNPS
cord-016903-z2vqfq98	120	3	transmitted	transmit	VBN
cord-016903-z2vqfq98	120	4	via	via	IN
cord-016903-z2vqfq98	120	5	person	person	NN
cord-016903-z2vqfq98	120	6	-	-	HYPH
cord-016903-z2vqfq98	120	7	to	to	IN
cord-016903-z2vqfq98	120	8	-	-	HYPH
cord-016903-z2vqfq98	120	9	person	person	NN
cord-016903-z2vqfq98	120	10	contacts	contact	NNS
cord-016903-z2vqfq98	120	11	but	but	CC
cord-016903-z2vqfq98	120	12	immunocompetent	immunocompetent	JJ
cord-016903-z2vqfq98	120	13	subjects	subject	NNS
cord-016903-z2vqfq98	121	1	mostly	mostly	RB
cord-016903-z2vqfq98	121	2	do	do	VBP
cord-016903-z2vqfq98	121	3	not	not	RB
cord-016903-z2vqfq98	121	4	recognize	recognize	VB
cord-016903-z2vqfq98	121	5	infection	infection	NN
cord-016903-z2vqfq98	121	6	as	as	IN
cord-016903-z2vqfq98	121	7	it	-PRON-	PRP
cord-016903-z2vqfq98	121	8	causes	cause	VBZ
cord-016903-z2vqfq98	121	9	no	no	DT
cord-016903-z2vqfq98	121	10	or	or	CC
cord-016903-z2vqfq98	121	11	few	few	JJ
cord-016903-z2vqfq98	121	12	unspecific	unspecific	JJ
cord-016903-z2vqfq98	121	13	symptoms	symptom	NNS
cord-016903-z2vqfq98	121	14	.	.	.
cord-016903-z2vqfq98	122	1	However	however	RB
cord-016903-z2vqfq98	122	2	,	,	,
cord-016903-z2vqfq98	122	3	a	a	DT
cord-016903-z2vqfq98	122	4	CMV	CMV	NNP
cord-016903-z2vqfq98	122	5	infection	infection	NN
cord-016903-z2vqfq98	122	6	represents	represent	VBZ
cord-016903-z2vqfq98	122	7	a	a	DT
cord-016903-z2vqfq98	122	8	severe	severe	JJ
cord-016903-z2vqfq98	122	9	health	health	NN
cord-016903-z2vqfq98	122	10	problem	problem	NN
cord-016903-z2vqfq98	122	11	in	in	IN
cord-016903-z2vqfq98	122	12	immunocompromised	immunocompromised	JJ
cord-016903-z2vqfq98	122	13	persons	person	NNS
cord-016903-z2vqfq98	122	14	(	(	-LRB-
cord-016903-z2vqfq98	122	15	e.g.	e.g.	RB
cord-016903-z2vqfq98	123	1	,	,	,
cord-016903-z2vqfq98	123	2	due	due	IN
cord-016903-z2vqfq98	123	3	to	to	IN
cord-016903-z2vqfq98	123	4	immunosuppressive	immunosuppressive	JJ
cord-016903-z2vqfq98	123	5	disease	disease	NN
cord-016903-z2vqfq98	123	6	,	,	,
cord-016903-z2vqfq98	123	7	chemotherapy	chemotherapy	NN
cord-016903-z2vqfq98	123	8	or	or	CC
cord-016903-z2vqfq98	123	9	transplantation	transplantation	NN
cord-016903-z2vqfq98	123	10	)	)	-RRB-
cord-016903-z2vqfq98	123	11	or	or	CC
cord-016903-z2vqfq98	123	12	in	in	IN
cord-016903-z2vqfq98	123	13	a	a	DT
cord-016903-z2vqfq98	123	14	fetus	fetus	NN
cord-016903-z2vqfq98	123	15	as	as	IN
cord-016903-z2vqfq98	123	16	a	a	DT
cord-016903-z2vqfq98	123	17	result	result	NN
cord-016903-z2vqfq98	123	18	of	of	IN
cord-016903-z2vqfq98	123	19	congenital	congenital	JJ
cord-016903-z2vqfq98	123	20	infection	infection	NN
cord-016903-z2vqfq98	123	21	.	.	.
cord-016903-z2vqfq98	124	1	Research	research	NN
cord-016903-z2vqfq98	124	2	results	result	NNS
cord-016903-z2vqfq98	124	3	over	over	IN
cord-016903-z2vqfq98	124	4	the	the	DT
cord-016903-z2vqfq98	124	5	past	past	JJ
cord-016903-z2vqfq98	124	6	decade	decade	NN
cord-016903-z2vqfq98	124	7	suggest	suggest	VBP
cord-016903-z2vqfq98	124	8	that	that	IN
cord-016903-z2vqfq98	124	9	CMV	CMV	NNP
cord-016903-z2vqfq98	124	10	favors	favor	VBZ
cord-016903-z2vqfq98	124	11	an	an	DT
cord-016903-z2vqfq98	124	12	accelerated	accelerate	VBN
cord-016903-z2vqfq98	124	13	aging	aging	NN
cord-016903-z2vqfq98	124	14	of	of	IN
cord-016903-z2vqfq98	124	15	the	the	DT
cord-016903-z2vqfq98	124	16	immune	immune	JJ
cord-016903-z2vqfq98	124	17	system	system	NN
cord-016903-z2vqfq98	124	18	as	as	IN
cord-016903-z2vqfq98	124	19	CMV	CMV	NNP
cord-016903-z2vqfq98	124	20	infection	infection	NN
cord-016903-z2vqfq98	124	21	is	be	VBZ
cord-016903-z2vqfq98	124	22	chronic	chronic	JJ
cord-016903-z2vqfq98	124	23	and	and	CC
cord-016903-z2vqfq98	124	24	the	the	DT
cord-016903-z2vqfq98	124	25	organism	organism	NN
cord-016903-z2vqfq98	124	26	is	be	VBZ
cord-016903-z2vqfq98	124	27	forced	force	VBN
cord-016903-z2vqfq98	124	28	to	to	TO
cord-016903-z2vqfq98	124	29	continuously	continuously	RB
cord-016903-z2vqfq98	124	30	prevent	prevent	VB
cord-016903-z2vqfq98	124	31	virus	virus	NN
cord-016903-z2vqfq98	124	32	reactivation	reactivation	NN
cord-016903-z2vqfq98	124	33	.	.	.
cord-016903-z2vqfq98	125	1	F	F	NNP
cord-016903-z2vqfq98	125	2	'	'	''
cord-016903-z2vqfq98	125	3	"	"	''
cord-016903-z2vqfq98	126	1	Despite	despite	IN
cord-016903-z2vqfq98	126	2	the	the	DT
cord-016903-z2vqfq98	126	3	high	high	JJ
cord-016903-z2vqfq98	126	4	frequency	frequency	NN
cord-016903-z2vqfq98	126	5	of	of	IN
cord-016903-z2vqfq98	126	6	CMV	CMV	NNP
cord-016903-z2vqfq98	126	7	-	-	HYPH
cord-016903-z2vqfq98	126	8	specific	specific	JJ
cord-016903-z2vqfq98	126	9	CD8	CD8	NNP
cord-016903-z2vqfq98	126	10	+	+	SYM
cord-016903-z2vqfq98	126	11	Tscells	Tscells	NNP
cord-016903-z2vqfq98	126	12	,	,	,
cord-016903-z2vqfq98	126	13	the	the	DT
cord-016903-z2vqfq98	126	14	virus	virus	NN
cord-016903-z2vqfq98	126	15	usually	usually	RB
cord-016903-z2vqfq98	126	16	can	can	MD
cord-016903-z2vqfq98	126	17	not	not	RB
cord-016903-z2vqfq98	126	18	be	be	VB
cord-016903-z2vqfq98	126	19	eliminated	eliminate	VBN
cord-016903-z2vqfq98	126	20	by	by	IN
cord-016903-z2vqfq98	126	21	the	the	DT
cord-016903-z2vqfq98	126	22	immune	immune	JJ
cord-016903-z2vqfq98	126	23	system	system	NN
cord-016903-z2vqfq98	126	24	.	.	.
cord-016903-z2vqfq98	127	1	This	this	DT
cord-016903-z2vqfq98	127	2	is	be	VBZ
cord-016903-z2vqfq98	127	3	because	because	IN
cord-016903-z2vqfq98	127	4	the	the	DT
cord-016903-z2vqfq98	127	5	virus	virus	NN
cord-016903-z2vqfq98	127	6	has	have	VBZ
cord-016903-z2vqfq98	127	7	evolved	evolve	VBN
cord-016903-z2vqfq98	127	8	several	several	JJ
cord-016903-z2vqfq98	127	9	mechanisms	mechanism	NNS
cord-016903-z2vqfq98	127	10	to	to	TO
cord-016903-z2vqfq98	127	11	escape	escape	VB
cord-016903-z2vqfq98	127	12	the	the	DT
cord-016903-z2vqfq98	127	13	host	host	NN
cord-016903-z2vqfq98	127	14	's	's	POS
cord-016903-z2vqfq98	127	15	immune	immune	JJ
cord-016903-z2vqfq98	127	16	defense	defense	NN
cord-016903-z2vqfq98	127	17	.	.	.
cord-016903-z2vqfq98	127	18	"	"	''
cord-016903-z2vqfq98	128	1	For	for	IN
cord-016903-z2vqfq98	128	2	instance	instance	NN
cord-016903-z2vqfq98	128	3	,	,	,
cord-016903-z2vqfq98	128	4	CMV	CMV	NNP
cord-016903-z2vqfq98	128	5	encodes	encode	VBZ
cord-016903-z2vqfq98	128	6	for	for	IN
cord-016903-z2vqfq98	128	7	a	a	DT
cord-016903-z2vqfq98	128	8	type	type	NN
cord-016903-z2vqfq98	128	9	ofproteins	ofprotein	NNS
cord-016903-z2vqfq98	128	10	called	call	VBN
cord-016903-z2vqfq98	128	11	immunoevasins	immunoevasin	NNS
cord-016903-z2vqfq98	128	12	that	that	WDT
cord-016903-z2vqfq98	128	13	modulate	modulate	VBP
cord-016903-z2vqfq98	128	14	the	the	DT
cord-016903-z2vqfq98	128	15	presentation	presentation	NN
cord-016903-z2vqfq98	128	16	ofviral	ofviral	JJ
cord-016903-z2vqfq98	128	17	peptides	peptide	NNS
cord-016903-z2vqfq98	128	18	or	or	CC
cord-016903-z2vqfq98	128	19	directly	directly	RB
cord-016903-z2vqfq98	128	20	suppress	suppress	VB
cord-016903-z2vqfq98	128	21	cellular	cellular	JJ
cord-016903-z2vqfq98	128	22	immune	immune	JJ
cord-016903-z2vqfq98	128	23	responses	response	NNS
cord-016903-z2vqfq98	128	24	.	.	.
cord-016903-z2vqfq98	129	1	Hence	hence	RB
cord-016903-z2vqfq98	129	2	,	,	,
cord-016903-z2vqfq98	129	3	the	the	DT
cord-016903-z2vqfq98	129	4	accumulation	accumulation	NN
cord-016903-z2vqfq98	129	5	of	of	IN
cord-016903-z2vqfq98	129	6	CMV	CMV	NNP
cord-016903-z2vqfq98	129	7	-	-	HYPH
cord-016903-z2vqfq98	129	8	specific	specific	JJ
cord-016903-z2vqfq98	129	9	T	t	NN
cord-016903-z2vqfq98	129	10	-	-	HYPH
cord-016903-z2vqfq98	129	11	cells	cell	NNS
cord-016903-z2vqfq98	129	12	substantially	substantially	RB
cord-016903-z2vqfq98	129	13	constricts	constrict	VBZ
cord-016903-z2vqfq98	129	14	the	the	DT
cord-016903-z2vqfq98	129	15	diversity	diversity	NN
cord-016903-z2vqfq98	129	16	of	of	IN
cord-016903-z2vqfq98	129	17	the	the	DT
cord-016903-z2vqfq98	129	18	T	t	NN
cord-016903-z2vqfq98	129	19	-	-	HYPH
cord-016903-z2vqfq98	129	20	cell	cell	NN
cord-016903-z2vqfq98	129	21	repertoire	repertoire	NN
cord-016903-z2vqfq98	129	22	"	"	''
cord-016903-z2vqfq98	129	23	and	and	CC
cord-016903-z2vqfq98	129	24	leads	lead	VBZ
cord-016903-z2vqfq98	129	25	to	to	IN
cord-016903-z2vqfq98	129	26	the	the	DT
cord-016903-z2vqfq98	129	27	production	production	NN
cord-016903-z2vqfq98	129	28	ofproinflammatory	ofproinflammatory	JJ
cord-016903-z2vqfq98	129	29	cytokines	cytokine	NNS
cord-016903-z2vqfq98	129	30	,	,	,
cord-016903-z2vqfq98	129	31	such	such	JJ
cord-016903-z2vqfq98	129	32	as	as	IN
cord-016903-z2vqfq98	129	33	gamma	gamma	NN
cord-016903-z2vqfq98	129	34	interferon	interferon	NN
cord-016903-z2vqfq98	129	35	and	and	CC
cord-016903-z2vqfq98	129	36	tumor	tumor	NN
cord-016903-z2vqfq98	129	37	necrosis	necrosis	NN
cord-016903-z2vqfq98	129	38	factor	factor	NN
cord-016903-z2vqfq98	129	39	alpha	alpha	NN
cord-016903-z2vqfq98	129	40	.	.	.
cord-016903-z2vqfq98	129	41	'	'	''
cord-016903-z2vqfq98	129	42	?	?	.
cord-016903-z2vqfq98	130	1	This	this	DT
cord-016903-z2vqfq98	130	2	imbalance	imbalance	NN
cord-016903-z2vqfq98	130	3	in	in	IN
cord-016903-z2vqfq98	130	4	the	the	DT
cord-016903-z2vqfq98	130	5	cytokine	cytokine	NN
cord-016903-z2vqfq98	130	6	production	production	NN
cord-016903-z2vqfq98	130	7	profile	profile	NN
cord-016903-z2vqfq98	130	8	may	may	MD
cord-016903-z2vqfq98	130	9	not	not	RB
cord-016903-z2vqfq98	130	10	only	only	RB
cord-016903-z2vqfq98	130	11	promote	promote	VB
cord-016903-z2vqfq98	130	12	the	the	DT
cord-016903-z2vqfq98	130	13	pathogenesis	pathogenesis	NN
cord-016903-z2vqfq98	130	14	of	of	IN
cord-016903-z2vqfq98	130	15	age	age	NN
cord-016903-z2vqfq98	130	16	-	-	HYPH
cord-016903-z2vqfq98	130	17	related	relate	VBN
cord-016903-z2vqfq98	130	18	diseasesf	diseasesf	NN
cord-016903-z2vqfq98	130	19	but	but	CC
cord-016903-z2vqfq98	130	20	leads	lead	VBZ
cord-016903-z2vqfq98	130	21	to	to	IN
cord-016903-z2vqfq98	130	22	a	a	DT
cord-016903-z2vqfq98	130	23	decreased	decreased	JJ
cord-016903-z2vqfq98	130	24	production	production	NN
cord-016903-z2vqfq98	130	25	of	of	IN
cord-016903-z2vqfq98	130	26	antibodies	antibody	NNS
cord-016903-z2vqfq98	130	27	following	follow	VBG
cord-016903-z2vqfq98	130	28	influenza	influenza	NN
cord-016903-z2vqfq98	130	29	vaccination	vaccination	NN
cord-016903-z2vqfq98	130	30	in	in	IN
cord-016903-z2vqfq98	130	31	elderly	elderly	JJ
cord-016903-z2vqfq98	130	32	persons.fA	persons.fa	NN
cord-016903-z2vqfq98	130	33	few	few	JJ
cord-016903-z2vqfq98	130	34	antiviral	antiviral	JJ
cord-016903-z2vqfq98	130	35	substances	substance	NNS
cord-016903-z2vqfq98	130	36	including	include	VBG
cord-016903-z2vqfq98	130	37	ganciclovir	ganciclovir	NNP
cord-016903-z2vqfq98	130	38	,	,	,
cord-016903-z2vqfq98	130	39	valganciclovir	valganciclovir	NNP
cord-016903-z2vqfq98	130	40	,	,	,
cord-016903-z2vqfq98	130	41	foscarnet	foscarnet	NN
cord-016903-z2vqfq98	130	42	and	and	CC
cord-016903-z2vqfq98	130	43	cidofovir	cidofovir	NNS
cord-016903-z2vqfq98	130	44	are	be	VBP
cord-016903-z2vqfq98	130	45	available	available	JJ
cord-016903-z2vqfq98	130	46	to	to	TO
cord-016903-z2vqfq98	130	47	prevent	prevent	VB
cord-016903-z2vqfq98	130	48	CMV	CMV	NNP
cord-016903-z2vqfq98	130	49	infection	infection	NN
cord-016903-z2vqfq98	130	50	in	in	IN
cord-016903-z2vqfq98	130	51	immunocompromised	immunocompromised	JJ
cord-016903-z2vqfq98	130	52	patients	patient	NNS
cord-016903-z2vqfq98	130	53	.	.	.
cord-016903-z2vqfq98	131	1	But	but	CC
cord-016903-z2vqfq98	131	2	antiviral	antiviral	JJ
cord-016903-z2vqfq98	131	3	therapy	therapy	NN
cord-016903-z2vqfq98	131	4	is	be	VBZ
cord-016903-z2vqfq98	131	5	limited	limit	VBN
cord-016903-z2vqfq98	131	6	by	by	IN
cord-016903-z2vqfq98	131	7	its	-PRON-	PRP$
cord-016903-z2vqfq98	131	8	severe	severe	JJ
cord-016903-z2vqfq98	131	9	adverse	adverse	JJ
cord-016903-z2vqfq98	131	10	reactions	reaction	NNS
cord-016903-z2vqfq98	131	11	,	,	,
cord-016903-z2vqfq98	131	12	such	such	JJ
cord-016903-z2vqfq98	131	13	as	as	IN
cord-016903-z2vqfq98	131	14	neutropenia	neutropenia	NN
cord-016903-z2vqfq98	131	15	,	,	,
cord-016903-z2vqfq98	131	16	nephrotoxicity	nephrotoxicity	NN
cord-016903-z2vqfq98	131	17	,	,	,
cord-016903-z2vqfq98	131	18	hypocalcemia	hypocalcemia	NN
cord-016903-z2vqfq98	131	19	and	and	CC
cord-016903-z2vqfq98	131	20	seizures	seizure	NNS
cord-016903-z2vqfq98	131	21	.	.	.
cord-016903-z2vqfq98	132	1	Another	another	DT
cord-016903-z2vqfq98	132	2	strategy	strategy	NN
cord-016903-z2vqfq98	132	3	is	be	VBZ
cord-016903-z2vqfq98	132	4	the	the	DT
cord-016903-z2vqfq98	132	5	adoptive	adoptive	JJ
cord-016903-z2vqfq98	132	6	transfer	transfer	NN
cord-016903-z2vqfq98	132	7	ofdonor	ofdonor	NN
cord-016903-z2vqfq98	132	8	-	-	HYPH
cord-016903-z2vqfq98	132	9	derived	derive	VBN
cord-016903-z2vqfq98	132	10	CMV	CMV	NNP
cord-016903-z2vqfq98	132	11	-	-	HYPH
cord-016903-z2vqfq98	132	12	specific	specific	JJ
cord-016903-z2vqfq98	132	13	CD4	CD4	NNP
cord-016903-z2vqfq98	132	14	+	+	CC
cord-016903-z2vqfq98	132	15	and	and	CC
cord-016903-z2vqfq98	132	16	CD8	CD8	NNP
cord-016903-z2vqfq98	132	17	+	+	CC
cord-016903-z2vqfq98	132	18	T	T	NNP
cord-016903-z2vqfq98	132	19	-	-	HYPH
cord-016903-z2vqfq98	132	20	cells	cell	NNS
cord-016903-z2vqfq98	132	21	that	that	WDT
cord-016903-z2vqfq98	132	22	may	may	MD
cord-016903-z2vqfq98	132	23	restore	restore	VB
cord-016903-z2vqfq98	132	24	the	the	DT
cord-016903-z2vqfq98	132	25	host	host	NN
cord-016903-z2vqfq98	132	26	's	's	POS
cord-016903-z2vqfq98	132	27	immunity	immunity	NN
cord-016903-z2vqfq98	132	28	against	against	IN
cord-016903-z2vqfq98	132	29	CMV	CMV	NNP
cord-016903-z2vqfq98	132	30	.	.	.
cord-016903-z2vqfq98	133	1	44	44	CD
cord-016903-z2vqfq98	134	1	Despite	despite	IN
cord-016903-z2vqfq98	134	2	the	the	DT
cord-016903-z2vqfq98	134	3	need	need	NN
cord-016903-z2vqfq98	134	4	ofa	ofa	NN
cord-016903-z2vqfq98	134	5	safe	safe	JJ
cord-016903-z2vqfq98	134	6	and	and	CC
cord-016903-z2vqfq98	134	7	potent	potent	JJ
cord-016903-z2vqfq98	134	8	vaccine	vaccine	NN
cord-016903-z2vqfq98	134	9	that	that	WDT
cord-016903-z2vqfq98	134	10	prevents	prevent	VBZ
cord-016903-z2vqfq98	134	11	CMV	CMV	NNP
cord-016903-z2vqfq98	134	12	disease	disease	NN
cord-016903-z2vqfq98	134	13	,	,	,
cord-016903-z2vqfq98	134	14	no	no	DT
cord-016903-z2vqfq98	134	15	vaccine	vaccine	NN
cord-016903-z2vqfq98	134	16	candidate	candidate	NN
cord-016903-z2vqfq98	134	17	has	have	VBZ
cord-016903-z2vqfq98	134	18	yet	yet	RB
cord-016903-z2vqfq98	134	19	entered	enter	VBN
cord-016903-z2vqfq98	134	20	the	the	DT
cord-016903-z2vqfq98	134	21	market	market	NN
cord-016903-z2vqfq98	134	22	.	.	.
cord-016903-z2vqfq98	135	1	A	a	DT
cord-016903-z2vqfq98	135	2	few	few	JJ
cord-016903-z2vqfq98	135	3	vaccines	vaccine	NNS
cord-016903-z2vqfq98	135	4	against	against	IN
cord-016903-z2vqfq98	135	5	CMV	CMV	NNP
cord-016903-z2vqfq98	135	6	are	be	VBP
cord-016903-z2vqfq98	135	7	currently	currently	RB
cord-016903-z2vqfq98	135	8	in	in	IN
cord-016903-z2vqfq98	135	9	phase	phase	NN
cord-016903-z2vqfq98	136	1	IIII	IIII	NNP
cord-016903-z2vqfq98	136	2	clinical	clinical	JJ
cord-016903-z2vqfq98	136	3	trials	trial	NNS
cord-016903-z2vqfq98	136	4	(	(	-LRB-
cord-016903-z2vqfq98	136	5	Table	table	NN
cord-016903-z2vqfq98	136	6	1	1	CD
cord-016903-z2vqfq98	136	7	)	)	-RRB-
cord-016903-z2vqfq98	136	8	.	.	.
cord-016903-z2vqfq98	137	1	Active	active	JJ
cord-016903-z2vqfq98	137	2	immunization	immunization	NN
cord-016903-z2vqfq98	137	3	against	against	IN
cord-016903-z2vqfq98	137	4	CMV	CMV	NNP
cord-016903-z2vqfq98	137	5	could	could	MD
cord-016903-z2vqfq98	137	6	reduce	reduce	VB
cord-016903-z2vqfq98	137	7	the	the	DT
cord-016903-z2vqfq98	137	8	incidence	incidence	NN
cord-016903-z2vqfq98	137	9	ofneonatal	ofneonatal	JJ
cord-016903-z2vqfq98	137	10	infections	infection	NNS
cord-016903-z2vqfq98	137	11	as	as	RB
cord-016903-z2vqfq98	137	12	well	well	RB
cord-016903-z2vqfq98	137	13	as	as	IN
cord-016903-z2vqfq98	137	14	complications	complication	NNS
cord-016903-z2vqfq98	137	15	in	in	IN
cord-016903-z2vqfq98	137	16	immunocompromised	immunocompromised	JJ
cord-016903-z2vqfq98	137	17	persons	person	NNS
cord-016903-z2vqfq98	137	18	and	and	CC
cord-016903-z2vqfq98	137	19	may	may	MD
cord-016903-z2vqfq98	137	20	prevent	prevent	VB
cord-016903-z2vqfq98	137	21	CMV	CMV	NNP
cord-016903-z2vqfq98	137	22	-	-	HYPH
cord-016903-z2vqfq98	137	23	associated	associate	VBN
cord-016903-z2vqfq98	137	24	premature	premature	JJ
cord-016903-z2vqfq98	137	25	aging	age	VBG
cord-016903-z2vqfq98	137	26	ofthe	ofthe	DT
cord-016903-z2vqfq98	137	27	immune	immune	JJ
cord-016903-z2vqfq98	137	28	system	system	NN
cord-016903-z2vqfq98	137	29	when	when	WRB
cord-016903-z2vqfq98	137	30	applied	apply	VBD
cord-016903-z2vqfq98	137	31	early	early	RB
cord-016903-z2vqfq98	137	32	in	in	IN
cord-016903-z2vqfq98	137	33	life	life	NN
cord-016903-z2vqfq98	137	34	.	.	.
cord-016903-z2vqfq98	138	1	Pertussis	pertussis	NN
cord-016903-z2vqfq98	138	2	(	(	-LRB-
cord-016903-z2vqfq98	138	3	whooping	whooping	JJ
cord-016903-z2vqfq98	138	4	cough	cough	NN
cord-016903-z2vqfq98	138	5	)	)	-RRB-
cord-016903-z2vqfq98	138	6	is	be	VBZ
cord-016903-z2vqfq98	138	7	a	a	DT
cord-016903-z2vqfq98	138	8	highly	highly	RB
cord-016903-z2vqfq98	138	9	contagious	contagious	JJ
cord-016903-z2vqfq98	138	10	respiratory	respiratory	JJ
cord-016903-z2vqfq98	138	11	system	system	NN
cord-016903-z2vqfq98	138	12	infection	infection	NN
cord-016903-z2vqfq98	138	13	caused	cause	VBN
cord-016903-z2vqfq98	138	14	by	by	IN
cord-016903-z2vqfq98	138	15	the	the	DT
cord-016903-z2vqfq98	138	16	bacterium	bacterium	NN
cord-016903-z2vqfq98	138	17	Bordetella	Bordetella	NNP
cord-016903-z2vqfq98	138	18	pertussis	pertussis	NN
cord-016903-z2vqfq98	138	19	and	and	CC
cord-016903-z2vqfq98	138	20	rarely	rarely	RB
cord-016903-z2vqfq98	138	21	by	by	IN
cord-016903-z2vqfq98	138	22	B.parapertussis	B.parapertussis	NNP
cord-016903-z2vqfq98	138	23	,	,	,
cord-016903-z2vqfq98	138	24	B.	B.	NNP
cord-016903-z2vqfq98	138	25	bronchiseptica	bronchiseptica	NNP
cord-016903-z2vqfq98	138	26	or	or	CC
cord-016903-z2vqfq98	138	27	other	other	JJ
cord-016903-z2vqfq98	138	28	pathogens	pathogen	NNS
cord-016903-z2vqfq98	138	29	.	.	.
cord-016903-z2vqfq98	139	1	Each	each	DT
cord-016903-z2vqfq98	139	2	year	year	NN
cord-016903-z2vqfq98	139	3	,	,	,
cord-016903-z2vqfq98	139	4	more	more	JJR
cord-016903-z2vqfq98	139	5	than	than	IN
cord-016903-z2vqfq98	139	6	20	20	CD
cord-016903-z2vqfq98	139	7	million	million	CD
cord-016903-z2vqfq98	139	8	cases	case	NNS
cord-016903-z2vqfq98	139	9	ofpertussis	ofpertussi	NNS
cord-016903-z2vqfq98	139	10	are	be	VBP
cord-016903-z2vqfq98	139	11	reported	report	VBN
cord-016903-z2vqfq98	139	12	worldwide	worldwide	RB
cord-016903-z2vqfq98	139	13	,	,	,
cord-016903-z2vqfq98	139	14	90	90	CD
cord-016903-z2vqfq98	139	15	%	%	NN
cord-016903-z2vqfq98	139	16	ofwhich	ofwhich	NNS
cord-016903-z2vqfq98	139	17	occur	occur	VBP
cord-016903-z2vqfq98	139	18	in	in	IN
cord-016903-z2vqfq98	139	19	developing	develop	VBG
cord-016903-z2vqfq98	139	20	countries	country	NNS
cord-016903-z2vqfq98	139	21	,	,	,
cord-016903-z2vqfq98	139	22	with	with	IN
cord-016903-z2vqfq98	139	23	an	an	DT
cord-016903-z2vqfq98	139	24	estimated	estimate	VBN
cord-016903-z2vqfq98	139	25	200,000	200,000	CD
cord-016903-z2vqfq98	139	26	to	to	TO
cord-016903-z2vqfq98	139	27	300,000	300,000	CD
cord-016903-z2vqfq98	139	28	fatalities	fatality	NNS
cord-016903-z2vqfq98	139	29	.	.	.
cord-016903-z2vqfq98	140	1	The	the	DT
cord-016903-z2vqfq98	140	2	implementation	implementation	NN
cord-016903-z2vqfq98	140	3	of	of	IN
cord-016903-z2vqfq98	140	4	routine	routine	JJ
cord-016903-z2vqfq98	140	5	childhood	childhood	NN
cord-016903-z2vqfq98	140	6	vaccination	vaccination	NN
cord-016903-z2vqfq98	140	7	against	against	IN
cord-016903-z2vqfq98	140	8	pertussis	pertussis	NN
cord-016903-z2vqfq98	140	9	has	have	VBZ
cord-016903-z2vqfq98	140	10	reduced	reduce	VBN
cord-016903-z2vqfq98	140	11	the	the	DT
cord-016903-z2vqfq98	140	12	high	high	JJ
cord-016903-z2vqfq98	140	13	mortality	mortality	NN
cord-016903-z2vqfq98	140	14	rate	rate	NN
cord-016903-z2vqfq98	140	15	among	among	IN
cord-016903-z2vqfq98	140	16	children	child	NNS
cord-016903-z2vqfq98	140	17	.	.	.
cord-016903-z2vqfq98	141	1	Although	although	IN
cord-016903-z2vqfq98	141	2	most	most	JJS
cord-016903-z2vqfq98	141	3	infants	infant	NNS
cord-016903-z2vqfq98	141	4	are	be	VBP
cord-016903-z2vqfq98	141	5	being	be	VBG
cord-016903-z2vqfq98	141	6	immunized	immunize	VBN
cord-016903-z2vqfq98	141	7	against	against	IN
cord-016903-z2vqfq98	141	8	pertussis	pertussis	NN
cord-016903-z2vqfq98	141	9	in	in	IN
cord-016903-z2vqfq98	141	10	industrialized	industrialize	VBN
cord-016903-z2vqfq98	141	11	countries	country	NNS
cord-016903-z2vqfq98	141	12	,	,	,
cord-016903-z2vqfq98	141	13	immunity	immunity	NN
cord-016903-z2vqfq98	141	14	usually	usually	RB
cord-016903-z2vqfq98	141	15	fades	fade	VBZ
cord-016903-z2vqfq98	141	16	during	during	IN
cord-016903-z2vqfq98	141	17	adolescence	adolescence	NN
cord-016903-z2vqfq98	141	18	.	.	.
cord-016903-z2vqfq98	142	1	Consequently	consequently	RB
cord-016903-z2vqfq98	142	2	,	,	,
cord-016903-z2vqfq98	142	3	a	a	DT
cord-016903-z2vqfq98	142	4	significant	significant	JJ
cord-016903-z2vqfq98	142	5	rise	rise	NN
cord-016903-z2vqfq98	142	6	in	in	IN
cord-016903-z2vqfq98	142	7	pertussis	pertussis	NN
cord-016903-z2vqfq98	142	8	incidence	incidence	NN
cord-016903-z2vqfq98	142	9	has	have	VBZ
cord-016903-z2vqfq98	142	10	been	be	VBN
cord-016903-z2vqfq98	142	11	noticed	notice	VBN
cord-016903-z2vqfq98	142	12	in	in	IN
cord-016903-z2vqfq98	142	13	adolescents	adolescent	NNS
cord-016903-z2vqfq98	142	14	and	and	CC
cord-016903-z2vqfq98	142	15	adults	adult	NNS
cord-016903-z2vqfq98	142	16	.	.	.
cord-016903-z2vqfq98	142	17	"	"	''
cord-016903-z2vqfq98	143	1	However	however	RB
cord-016903-z2vqfq98	143	2	,	,	,
cord-016903-z2vqfq98	143	3	the	the	DT
cord-016903-z2vqfq98	143	4	reported	report	VBN
cord-016903-z2vqfq98	143	5	pertussis	pertussis	NN
cord-016903-z2vqfq98	143	6	cases	case	NNS
cord-016903-z2vqfq98	143	7	in	in	IN
cord-016903-z2vqfq98	143	8	adults	adult	NNS
cord-016903-z2vqfq98	143	9	and	and	CC
cord-016903-z2vqfq98	143	10	elderly	elderly	JJ
cord-016903-z2vqfq98	143	11	people	people	NNS
cord-016903-z2vqfq98	143	12	are	be	VBP
cord-016903-z2vqfq98	143	13	likely	likely	JJ
cord-016903-z2vqfq98	143	14	to	to	TO
cord-016903-z2vqfq98	143	15	be	be	VB
cord-016903-z2vqfq98	143	16	underestimated	underestimate	VBN
cord-016903-z2vqfq98	143	17	because	because	IN
cord-016903-z2vqfq98	143	18	symptoms	symptom	NNS
cord-016903-z2vqfq98	143	19	ofdisease	ofdisease	MD
cord-016903-z2vqfq98	143	20	may	may	MD
cord-016903-z2vqfq98	143	21	be	be	VB
cord-016903-z2vqfq98	143	22	characterless	characterless	JJ
cord-016903-z2vqfq98	143	23	and	and	CC
cord-016903-z2vqfq98	143	24	make	make	VB
cord-016903-z2vqfq98	143	25	clinical	clinical	JJ
cord-016903-z2vqfq98	143	26	diagnosis	diagnosis	NN
cord-016903-z2vqfq98	143	27	difficult	difficult	JJ
cord-016903-z2vqfq98	143	28	.	.	.
cord-016903-z2vqfq98	144	1	Among	among	IN
cord-016903-z2vqfq98	144	2	nonvaccinated	nonvaccinate	VBN
cord-016903-z2vqfq98	144	3	elderly	elderly	JJ
cord-016903-z2vqfq98	144	4	people	people	NNS
cord-016903-z2vqfq98	144	5	the	the	DT
cord-016903-z2vqfq98	144	6	attack	attack	NN
cord-016903-z2vqfq98	144	7	rate	rate	NN
cord-016903-z2vqfq98	144	8	ofpertussis	ofpertussis	NN
cord-016903-z2vqfq98	144	9	is	be	VBZ
cord-016903-z2vqfq98	144	10	high	high	JJ
cord-016903-z2vqfq98	144	11	(	(	-LRB-
cord-016903-z2vqfq98	144	12	53	53	CD
cord-016903-z2vqfq98	144	13	%	%	NN
cord-016903-z2vqfq98	144	14	)	)	-RRB-
cord-016903-z2vqfq98	144	15	and	and	CC
cord-016903-z2vqfq98	144	16	up	up	IN
cord-016903-z2vqfq98	144	17	to	to	TO
cord-016903-z2vqfq98	144	18	10	10	CD
cord-016903-z2vqfq98	144	19	%	%	NN
cord-016903-z2vqfq98	144	20	ofelderly	ofelderly	JJ
cord-016903-z2vqfq98	144	21	persons	person	NNS
cord-016903-z2vqfq98	144	22	may	may	MD
cord-016903-z2vqfq98	144	23	die	die	VB
cord-016903-z2vqfq98	144	24	from	from	IN
cord-016903-z2vqfq98	144	25	intracranial	intracranial	JJ
cord-016903-z2vqfq98	144	26	bleeding	bleeding	NN
cord-016903-z2vqfq98	144	27	while	while	IN
cord-016903-z2vqfq98	144	28	they	-PRON-	PRP
cord-016903-z2vqfq98	144	29	are	be	VBP
cord-016903-z2vqfq98	144	30	symptomatic	symptomatic	JJ
cord-016903-z2vqfq98	144	31	for	for	IN
cord-016903-z2vqfq98	144	32	pertussis	pertussis	NN
cord-016903-z2vqfq98	144	33	.	.	.
cord-016903-z2vqfq98	144	34	"	"	''
cord-016903-z2vqfq98	145	1	Regular	regular	JJ
cord-016903-z2vqfq98	145	2	booster	booster	NN
cord-016903-z2vqfq98	145	3	immunizations	immunization	NNS
cord-016903-z2vqfq98	145	4	should	should	MD
cord-016903-z2vqfq98	145	5	thus	thus	RB
cord-016903-z2vqfq98	145	6	be	be	VB
cord-016903-z2vqfq98	145	7	considered	consider	VBN
cord-016903-z2vqfq98	145	8	for	for	IN
cord-016903-z2vqfq98	145	9	adults	adult	NNS
cord-016903-z2vqfq98	145	10	and	and	CC
cord-016903-z2vqfq98	145	11	elderly	elderly	JJ
cord-016903-z2vqfq98	145	12	persons	person	NNS
cord-016903-z2vqfq98	145	13	,	,	,
cord-016903-z2vqfq98	145	14	which	which	WDT
cord-016903-z2vqfq98	145	15	is	be	VBZ
cord-016903-z2vqfq98	145	16	indispensable	indispensable	JJ
cord-016903-z2vqfq98	145	17	to	to	TO
cord-016903-z2vqfq98	145	18	remain	remain	VB
cord-016903-z2vqfq98	145	19	protected	protect	VBN
cord-016903-z2vqfq98	145	20	from	from	IN
cord-016903-z2vqfq98	145	21	disease	disease	NN
cord-016903-z2vqfq98	145	22	.	.	.
cord-016903-z2vqfq98	146	1	Tetanus	Tetanus	NNP
cord-016903-z2vqfq98	146	2	is	be	VBZ
cord-016903-z2vqfq98	146	3	acquired	acquire	VBN
cord-016903-z2vqfq98	146	4	via	via	IN
cord-016903-z2vqfq98	146	5	environmental	environmental	JJ
cord-016903-z2vqfq98	146	6	exposure	exposure	NN
cord-016903-z2vqfq98	146	7	to	to	IN
cord-016903-z2vqfq98	146	8	the	the	DT
cord-016903-z2vqfq98	146	9	spores	spore	NNS
cord-016903-z2vqfq98	146	10	of	of	IN
cord-016903-z2vqfq98	146	11	Clostridium	clostridium	NN
cord-016903-z2vqfq98	146	12	tetani	tetani	NN
cord-016903-z2vqfq98	146	13	,	,	,
cord-016903-z2vqfq98	146	14	which	which	WDT
cord-016903-z2vqfq98	146	15	are	be	VBP
cord-016903-z2vqfq98	146	16	present	present	JJ
cord-016903-z2vqfq98	146	17	in	in	IN
cord-016903-z2vqfq98	146	18	soil	soil	NN
cord-016903-z2vqfq98	146	19	worldwide	worldwide	RB
cord-016903-z2vqfq98	146	20	.	.	.
cord-016903-z2vqfq98	147	1	The	the	DT
cord-016903-z2vqfq98	147	2	disease	disease	NN
cord-016903-z2vqfq98	147	3	is	be	VBZ
cord-016903-z2vqfq98	147	4	caused	cause	VBN
cord-016903-z2vqfq98	147	5	by	by	IN
cord-016903-z2vqfq98	147	6	a	a	DT
cord-016903-z2vqfq98	147	7	potent	potent	JJ
cord-016903-z2vqfq98	147	8	neurotoxin	neurotoxin	NN
cord-016903-z2vqfq98	147	9	produced	produce	VBN
cord-016903-z2vqfq98	147	10	by	by	IN
cord-016903-z2vqfq98	147	11	the	the	DT
cord-016903-z2vqfq98	147	12	bacterium	bacterium	NN
cord-016903-z2vqfq98	147	13	in	in	IN
cord-016903-z2vqfq98	147	14	dead	dead	JJ
cord-016903-z2vqfq98	147	15	tissue	tissue	NN
cord-016903-z2vqfq98	147	16	,	,	,
cord-016903-z2vqfq98	147	17	e.g	e.g	NNP
cord-016903-z2vqfq98	147	18	.	.	NNP
cord-016903-z2vqfq98	147	19	,dirty	,dirty	NNP
cord-016903-z2vqfq98	147	20	wounds	wound	NNS
cord-016903-z2vqfq98	147	21	.	.	.
cord-016903-z2vqfq98	148	1	Diphtheria	diphtheria	NN
cord-016903-z2vqfq98	148	2	is	be	VBZ
cord-016903-z2vqfq98	148	3	a	a	DT
cord-016903-z2vqfq98	148	4	bacterial	bacterial	JJ
cord-016903-z2vqfq98	148	5	disease	disease	NN
cord-016903-z2vqfq98	148	6	caused	cause	VBN
cord-016903-z2vqfq98	148	7	by	by	IN
cord-016903-z2vqfq98	148	8	Corynebacterium	Corynebacterium	NNP
cord-016903-z2vqfq98	148	9	diphtheriac	diphtheriac	NNP
cord-016903-z2vqfq98	148	10	and	and	CC
cord-016903-z2vqfq98	148	11	is	be	VBZ
cord-016903-z2vqfq98	148	12	transmitted	transmit	VBN
cord-016903-z2vqfq98	148	13	from	from	IN
cord-016903-z2vqfq98	148	14	person	person	NN
cord-016903-z2vqfq98	148	15	to	to	IN
cord-016903-z2vqfq98	148	16	person	person	NN
cord-016903-z2vqfq98	148	17	through	through	IN
cord-016903-z2vqfq98	148	18	close	close	JJ
cord-016903-z2vqfq98	148	19	physical	physical	JJ
cord-016903-z2vqfq98	148	20	contact	contact	NN
cord-016903-z2vqfq98	148	21	.	.	.
cord-016903-z2vqfq98	149	1	The	the	DT
cord-016903-z2vqfq98	149	2	public	public	JJ
cord-016903-z2vqfq98	149	3	health	health	NN
cord-016903-z2vqfq98	149	4	burden	burden	NN
cord-016903-z2vqfq98	149	5	ofboth	ofboth	NNP
cord-016903-z2vqfq98	149	6	diseaseshas	diseaseshas	NNP
cord-016903-z2vqfq98	149	7	been	be	VBN
cord-016903-z2vqfq98	149	8	low	low	JJ
cord-016903-z2vqfq98	149	9	in	in	IN
cord-016903-z2vqfq98	149	10	developed	develop	VBN
cord-016903-z2vqfq98	149	11	countries	country	NNS
cord-016903-z2vqfq98	149	12	due	due	JJ
cord-016903-z2vqfq98	149	13	to	to	IN
cord-016903-z2vqfq98	149	14	routine	routine	JJ
cord-016903-z2vqfq98	149	15	immunization	immunization	NN
cord-016903-z2vqfq98	149	16	.	.	.
cord-016903-z2vqfq98	150	1	However	however	RB
cord-016903-z2vqfq98	150	2	,	,	,
cord-016903-z2vqfq98	150	3	outbreaks	outbreak	NNS
cord-016903-z2vqfq98	150	4	ofdiphtheria	ofdiphtheria	NNS
cord-016903-z2vqfq98	150	5	have	have	VBP
cord-016903-z2vqfq98	150	6	been	be	VBN
cord-016903-z2vqfq98	150	7	reported	report	VBN
cord-016903-z2vqfq98	150	8	in	in	IN
cord-016903-z2vqfq98	150	9	the	the	DT
cord-016903-z2vqfq98	150	10	independent	independent	JJ
cord-016903-z2vqfq98	150	11	states	state	NNS
cord-016903-z2vqfq98	150	12	ofthe	ofthe	DT
cord-016903-z2vqfq98	150	13	former	former	JJ
cord-016903-z2vqfq98	150	14	Soviet	Soviet	NNP
cord-016903-z2vqfq98	150	15	Union	Union	NNP
cord-016903-z2vqfq98	150	16	,	,	,
cord-016903-z2vqfq98	150	17	Algeria	Algeria	NNP
cord-016903-z2vqfq98	150	18	,	,	,
cord-016903-z2vqfq98	150	19	China	China	NNP
cord-016903-z2vqfq98	150	20	,	,	,
cord-016903-z2vqfq98	150	21	Iraq	Iraq	NNP
cord-016903-z2vqfq98	150	22	,	,	,
cord-016903-z2vqfq98	150	23	Sudan	Sudan	NNP
cord-016903-z2vqfq98	150	24	,	,	,
cord-016903-z2vqfq98	150	25	Thailand	Thailand	NNP
cord-016903-z2vqfq98	150	26	and	and	CC
cord-016903-z2vqfq98	150	27	other	other	JJ
cord-016903-z2vqfq98	150	28	countries	country	NNS
cord-016903-z2vqfq98	150	29	.	.	.
cord-016903-z2vqfq98	151	1	Thus	thus	RB
cord-016903-z2vqfq98	151	2	,	,	,
cord-016903-z2vqfq98	151	3	maintaining	maintain	VBG
cord-016903-z2vqfq98	151	4	high	high	JJ
cord-016903-z2vqfq98	151	5	vaccination	vaccination	NN
cord-016903-z2vqfq98	151	6	coverage	coverage	NN
cord-016903-z2vqfq98	151	7	is	be	VBZ
cord-016903-z2vqfq98	151	8	important	important	JJ
cord-016903-z2vqfq98	151	9	to	to	TO
cord-016903-z2vqfq98	151	10	prevent	prevent	VB
cord-016903-z2vqfq98	151	11	the	the	DT
cord-016903-z2vqfq98	151	12	outbreak	outbreak	NN
cord-016903-z2vqfq98	151	13	of	of	IN
cord-016903-z2vqfq98	151	14	new	new	JJ
cord-016903-z2vqfq98	151	15	diphtheria	diphtheria	NN
cord-016903-z2vqfq98	151	16	epidemics	epidemic	NNS
cord-016903-z2vqfq98	151	17	.	.	.
cord-016903-z2vqfq98	152	1	Although	although	IN
cord-016903-z2vqfq98	152	2	vaccines	vaccine	NNS
cord-016903-z2vqfq98	152	3	that	that	WDT
cord-016903-z2vqfq98	152	4	prevent	prevent	VBP
cord-016903-z2vqfq98	152	5	from	from	IN
cord-016903-z2vqfq98	152	6	tetanus	tetanus	NN
cord-016903-z2vqfq98	152	7	and	and	CC
cord-016903-z2vqfq98	152	8	diphtheria	diphtheria	NN
cord-016903-z2vqfq98	152	9	have	have	VBP
cord-016903-z2vqfq98	152	10	been	be	VBN
cord-016903-z2vqfq98	152	11	used	use	VBN
cord-016903-z2vqfq98	152	12	for	for	IN
cord-016903-z2vqfq98	152	13	routine	routine	JJ
cord-016903-z2vqfq98	152	14	immunization	immunization	NN
cord-016903-z2vqfq98	152	15	for	for	IN
cord-016903-z2vqfq98	152	16	a	a	DT
cord-016903-z2vqfq98	152	17	long	long	JJ
cord-016903-z2vqfq98	152	18	time	time	NN
cord-016903-z2vqfq98	152	19	all	all	RB
cord-016903-z2vqfq98	152	20	over	over	IN
cord-016903-z2vqfq98	152	21	the	the	DT
cord-016903-z2vqfq98	152	22	world	world	NN
cord-016903-z2vqfq98	152	23	,	,	,
cord-016903-z2vqfq98	152	24	few	few	JJ
cord-016903-z2vqfq98	152	25	studies	study	NNS
cord-016903-z2vqfq98	152	26	exist	exist	VBP
cord-016903-z2vqfq98	152	27	that	that	DT
cord-016903-z2vqfq98	152	28	document	document	NN
cord-016903-z2vqfq98	152	29	their	-PRON-	PRP$
cord-016903-z2vqfq98	152	30	efficacyin	efficacyin	JJ
cord-016903-z2vqfq98	152	31	elderly	elderly	JJ
cord-016903-z2vqfq98	152	32	people	people	NNS
cord-016903-z2vqfq98	152	33	.	.	.
cord-016903-z2vqfq98	153	1	The	the	DT
cord-016903-z2vqfq98	153	2	vaccination	vaccination	NN
cord-016903-z2vqfq98	153	3	coverage	coverage	NN
cord-016903-z2vqfq98	153	4	among	among	IN
cord-016903-z2vqfq98	153	5	elderly	elderly	JJ
cord-016903-z2vqfq98	153	6	subjects	subject	NNS
cord-016903-z2vqfq98	153	7	is	be	VBZ
cord-016903-z2vqfq98	153	8	decreasing	decrease	VBG
cord-016903-z2vqfq98	153	9	in	in	IN
cord-016903-z2vqfq98	153	10	several	several	JJ
cord-016903-z2vqfq98	153	11	European	european	JJ
cord-016903-z2vqfq98	153	12	countries	country	NNS
cord-016903-z2vqfq98	153	13	and	and	CC
cord-016903-z2vqfq98	153	14	up	up	IN
cord-016903-z2vqfq98	153	15	to	to	TO
cord-016903-z2vqfq98	153	16	40	40	CD
cord-016903-z2vqfq98	153	17	%	%	NN
cord-016903-z2vqfq98	153	18	of	of	IN
cord-016903-z2vqfq98	153	19	appropriately	appropriately	RB
cord-016903-z2vqfq98	153	20	vaccinated	vaccinate	VBN
cord-016903-z2vqfq98	153	21	elderly	elderly	JJ
cord-016903-z2vqfq98	153	22	persons	person	NNS
cord-016903-z2vqfq98	153	23	do	do	VBP
cord-016903-z2vqfq98	153	24	not	not	RB
cord-016903-z2vqfq98	153	25	have	have	VB
cord-016903-z2vqfq98	153	26	protective	protective	JJ
cord-016903-z2vqfq98	153	27	tetanus	tetanus	RB
cord-016903-z2vqfq98	153	28	-	-	HYPH
cord-016903-z2vqfq98	153	29	specific	specific	JJ
cord-016903-z2vqfq98	153	30	antibody	antibody	NN
cord-016903-z2vqfq98	153	31	concentrations	concentration	NNS
cord-016903-z2vqfq98	153	32	.	.	.
cord-016903-z2vqfq98	154	1	47	47	CD
cord-016903-z2vqfq98	154	2	-	-	SYM
cord-016903-z2vqfq98	154	3	49Therefore	49therefore	CD
cord-016903-z2vqfq98	154	4	,	,	,
cord-016903-z2vqfq98	154	5	public	public	JJ
cord-016903-z2vqfq98	154	6	health	health	NN
cord-016903-z2vqfq98	154	7	authorities	authority	NNS
cord-016903-z2vqfq98	154	8	ofsome	ofsome	IN
cord-016903-z2vqfq98	154	9	European	european	JJ
cord-016903-z2vqfq98	154	10	countries	country	NNS
cord-016903-z2vqfq98	154	11	have	have	VBP
cord-016903-z2vqfq98	154	12	recommended	recommend	VBN
cord-016903-z2vqfq98	154	13	five	five	CD
cord-016903-z2vqfq98	154	14	instead	instead	RB
cord-016903-z2vqfq98	154	15	often	often	RB
cord-016903-z2vqfq98	154	16	year	year	NN
cord-016903-z2vqfq98	154	17	booster	booster	NN
cord-016903-z2vqfq98	154	18	vaccination	vaccination	NN
cord-016903-z2vqfq98	154	19	intervals	interval	NNS
cord-016903-z2vqfq98	154	20	for	for	IN
cord-016903-z2vqfq98	154	21	people	people	NNS
cord-016903-z2vqfq98	154	22	over	over	IN
cord-016903-z2vqfq98	154	23	60	60	CD
cord-016903-z2vqfq98	154	24	years	year	NNS
cord-016903-z2vqfq98	154	25	ofage	ofage	RB
cord-016903-z2vqfq98	154	26	.	.	.
cord-016903-z2vqfq98	155	1	Additionally	additionally	RB
cord-016903-z2vqfq98	155	2	,	,	,
cord-016903-z2vqfq98	155	3	strategies	strategy	NNS
cord-016903-z2vqfq98	155	4	should	should	MD
cord-016903-z2vqfq98	155	5	be	be	VB
cord-016903-z2vqfq98	155	6	developed	develop	VBN
cord-016903-z2vqfq98	155	7	to	to	TO
cord-016903-z2vqfq98	155	8	draw	draw	VB
cord-016903-z2vqfq98	155	9	public	public	JJ
cord-016903-z2vqfq98	155	10	attention	attention	NN
cord-016903-z2vqfq98	155	11	to	to	IN
cord-016903-z2vqfq98	155	12	the	the	DT
cord-016903-z2vqfq98	155	13	problem	problem	NN
cord-016903-z2vqfq98	155	14	ofimmunizations	ofimmunization	VBZ
cord-016903-z2vqfq98	155	15	in	in	IN
cord-016903-z2vqfq98	155	16	the	the	DT
cord-016903-z2vqfq98	155	17	elderly	elderly	JJ
cord-016903-z2vqfq98	155	18	,	,	,
cord-016903-z2vqfq98	155	19	to	to	TO
cord-016903-z2vqfq98	155	20	inform	inform	VB
cord-016903-z2vqfq98	155	21	general	general	JJ
cord-016903-z2vqfq98	155	22	practitioners	practitioner	NNS
cord-016903-z2vqfq98	155	23	and	and	CC
cord-016903-z2vqfq98	155	24	to	to	TO
cord-016903-z2vqfq98	155	25	increase	increase	VB
cord-016903-z2vqfq98	155	26	vaccination	vaccination	NN
cord-016903-z2vqfq98	155	27	acceptance	acceptance	NN
cord-016903-z2vqfq98	155	28	.	.	.
cord-016903-z2vqfq98	156	1	The	the	DT
cord-016903-z2vqfq98	156	2	increasing	increase	VBG
cord-016903-z2vqfq98	156	3	mobility	mobility	NN
cord-016903-z2vqfq98	156	4	ofelderly	ofelderly	JJ
cord-016903-z2vqfq98	156	5	persons	person	NNS
cord-016903-z2vqfq98	156	6	recognized	recognize	VBN
cord-016903-z2vqfq98	156	7	worldwide	worldwide	RB
cord-016903-z2vqfq98	156	8	is	be	VBZ
cord-016903-z2vqfq98	156	9	accompanied	accompany	VBN
cord-016903-z2vqfq98	156	10	by	by	IN
cord-016903-z2vqfq98	156	11	an	an	DT
cord-016903-z2vqfq98	156	12	enhanced	enhanced	JJ
cord-016903-z2vqfq98	156	13	risk	risk	NN
cord-016903-z2vqfq98	156	14	to	to	TO
cord-016903-z2vqfq98	156	15	encounter	encounter	VB
cord-016903-z2vqfq98	156	16	new	new	JJ
cord-016903-z2vqfq98	156	17	antigens	antigen	NNS
cord-016903-z2vqfq98	156	18	.	.	.
cord-016903-z2vqfq98	157	1	This	this	DT
cord-016903-z2vqfq98	157	2	may	may	MD
cord-016903-z2vqfq98	157	3	be	be	VB
cord-016903-z2vqfq98	157	4	ofconcern	ofconcern	NNP
cord-016903-z2vqfq98	157	5	because	because	IN
cord-016903-z2vqfq98	157	6	elderly	elderly	JJ
cord-016903-z2vqfq98	157	7	persons	person	NNS
cord-016903-z2vqfq98	157	8	possess	possess	VBP
cord-016903-z2vqfq98	157	9	a	a	DT
cord-016903-z2vqfq98	157	10	limited	limited	JJ
cord-016903-z2vqfq98	157	11	T	t	NN
cord-016903-z2vqfq98	157	12	-	-	HYPH
cord-016903-z2vqfq98	157	13	cell	cell	NN
cord-016903-z2vqfq98	157	14	repertoire	repertoire	NN
cord-016903-z2vqfq98	157	15	that	that	WDT
cord-016903-z2vqfq98	157	16	may	may	MD
cord-016903-z2vqfq98	157	17	not	not	RB
cord-016903-z2vqfq98	157	18	guarantee	guarantee	VB
cord-016903-z2vqfq98	157	19	full	full	JJ
cord-016903-z2vqfq98	157	20	responsiveness	responsiveness	NN
cord-016903-z2vqfq98	157	21	to	to	IN
cord-016903-z2vqfq98	157	22	a	a	DT
cord-016903-z2vqfq98	157	23	wide	wide	JJ
cord-016903-z2vqfq98	157	24	variety	variety	NN
cord-016903-z2vqfq98	157	25	ofnew	ofnew	NN
cord-016903-z2vqfq98	157	26	antigens	antigen	NNS
cord-016903-z2vqfq98	157	27	(	(	-LRB-
cord-016903-z2vqfq98	157	28	see	see	VB
cord-016903-z2vqfq98	157	29	below	below	RB
cord-016903-z2vqfq98	157	30	for	for	IN
cord-016903-z2vqfq98	157	31	details	detail	NNS
cord-016903-z2vqfq98	157	32	)	)	-RRB-
cord-016903-z2vqfq98	157	33	.	.	.
cord-016903-z2vqfq98	158	1	Nevertheless	nevertheless	RB
cord-016903-z2vqfq98	158	2	,	,	,
cord-016903-z2vqfq98	158	3	in	in	IN
cord-016903-z2vqfq98	158	4	vitro	vitro	FW
cord-016903-z2vqfq98	158	5	experiments	experiment	NNS
cord-016903-z2vqfq98	158	6	have	have	VBP
cord-016903-z2vqfq98	158	7	demonstrated	demonstrate	VBN
cord-016903-z2vqfq98	158	8	that	that	IN
cord-016903-z2vqfq98	158	9	naive	naive	JJ
cord-016903-z2vqfq98	158	10	T	t	NN
cord-016903-z2vqfq98	158	11	-	-	HYPH
cord-016903-z2vqfq98	158	12	cells	cell	NNS
cord-016903-z2vqfq98	158	13	from	from	IN
cord-016903-z2vqfq98	158	14	elderly	elderly	JJ
cord-016903-z2vqfq98	158	15	persons	person	NNS
cord-016903-z2vqfq98	158	16	can	can	MD
cord-016903-z2vqfq98	158	17	still	still	RB
cord-016903-z2vqfq98	158	18	be	be	VB
cord-016903-z2vqfq98	158	19	stimulated	stimulate	VBN
cord-016903-z2vqfq98	158	20	by	by	IN
cord-016903-z2vqfq98	158	21	neoantigens	neoantigen	NNS
cord-016903-z2vqfq98	158	22	,	,	,
cord-016903-z2vqfq98	158	23	at	at	IN
cord-016903-z2vqfq98	158	24	least	least	JJS
cord-016903-z2vqfq98	158	25	to	to	IN
cord-016903-z2vqfq98	158	26	the	the	DT
cord-016903-z2vqfq98	158	27	recombinant	recombinant	JJ
cord-016903-z2vqfq98	158	28	Etr	Etr	NNP
cord-016903-z2vqfq98	158	29	protein	protein	NN
cord-016903-z2vqfq98	158	30	of	of	IN
cord-016903-z2vqfq98	158	31	TBE	TBE	NNP
cord-016903-z2vqfq98	158	32	virus	virus	NN
cord-016903-z2vqfq98	158	33	and	and	CC
cord-016903-z2vqfq98	158	34	rabies	rabies	NN
cord-016903-z2vqfq98	158	35	virus	virus	NN
cord-016903-z2vqfq98	158	36	.	.	.
cord-016903-z2vqfq98	158	37	"	"	''
cord-016903-z2vqfq98	159	1	Based	base	VBN
cord-016903-z2vqfq98	159	2	on	on	IN
cord-016903-z2vqfq98	159	3	an	an	DT
cord-016903-z2vqfq98	159	4	assessment	assessment	NN
cord-016903-z2vqfq98	159	5	of	of	IN
cord-016903-z2vqfq98	159	6	the	the	DT
cord-016903-z2vqfq98	159	7	risks	risk	NNS
cord-016903-z2vqfq98	159	8	for	for	IN
cord-016903-z2vqfq98	159	9	travel	travel	NN
cord-016903-z2vqfq98	159	10	-	-	HYPH
cord-016903-z2vqfq98	159	11	related	relate	VBN
cord-016903-z2vqfq98	159	12	diseases	disease	NNS
cord-016903-z2vqfq98	159	13	,	,	,
cord-016903-z2vqfq98	159	14	including	include	VBG
cord-016903-z2vqfq98	159	15	the	the	DT
cord-016903-z2vqfq98	159	16	destination	destination	NN
cord-016903-z2vqfq98	159	17	,	,	,
cord-016903-z2vqfq98	159	18	the	the	DT
cord-016903-z2vqfq98	159	19	type	type	NN
cord-016903-z2vqfq98	159	20	of	of	IN
cord-016903-z2vqfq98	159	21	journey	journey	NN
cord-016903-z2vqfq98	159	22	and	and	CC
cord-016903-z2vqfq98	159	23	the	the	DT
cord-016903-z2vqfq98	159	24	duration	duration	NN
cord-016903-z2vqfq98	159	25	,	,	,
cord-016903-z2vqfq98	159	26	vaccination	vaccination	NN
cord-016903-z2vqfq98	159	27	is	be	VBZ
cord-016903-z2vqfq98	159	28	recommended	recommend	VBN
cord-016903-z2vqfq98	159	29	to	to	TO
cord-016903-z2vqfq98	159	30	protect	protect	VB
cord-016903-z2vqfq98	159	31	from	from	IN
cord-016903-z2vqfq98	159	32	typhoid	typhoid	NN
cord-016903-z2vqfq98	159	33	and	and	CC
cord-016903-z2vqfq98	159	34	yellow	yellow	JJ
cord-016903-z2vqfq98	159	35	fever	fever	NN
cord-016903-z2vqfq98	159	36	,	,	,
cord-016903-z2vqfq98	159	37	hepatitis	hepatitis	NNP
cord-016903-z2vqfq98	159	38	A	a	NN
cord-016903-z2vqfq98	159	39	and	and	CC
cord-016903-z2vqfq98	159	40	B	b	NN
cord-016903-z2vqfq98	159	41	,	,	,
cord-016903-z2vqfq98	159	42	Japanese	japanese	JJ
cord-016903-z2vqfq98	159	43	encephalitis	encephalitis	RB
cord-016903-z2vqfq98	159	44	,	,	,
cord-016903-z2vqfq98	159	45	tick	tick	VB
cord-016903-z2vqfq98	159	46	-	-	HYPH
cord-016903-z2vqfq98	159	47	borne	bear	VBN
cord-016903-z2vqfq98	159	48	encephalitis	encephalitis	JJ
cord-016903-z2vqfq98	159	49	(	(	-LRB-
cord-016903-z2vqfq98	159	50	TBE	TBE	NNP
cord-016903-z2vqfq98	159	51	)	)	-RRB-
cord-016903-z2vqfq98	159	52	or	or	CC
cord-016903-z2vqfq98	159	53	rabies	rabie	NNS
cord-016903-z2vqfq98	159	54	.	.	.
cord-016903-z2vqfq98	160	1	But	but	CC
cord-016903-z2vqfq98	160	2	elderly	elderly	JJ
cord-016903-z2vqfq98	160	3	persons	person	NNS
cord-016903-z2vqfq98	160	4	should	should	MD
cord-016903-z2vqfq98	160	5	also	also	RB
cord-016903-z2vqfq98	160	6	check	check	VB
cord-016903-z2vqfq98	160	7	whether	whether	IN
cord-016903-z2vqfq98	160	8	they	-PRON-	PRP
cord-016903-z2vqfq98	160	9	have	have	VBP
cord-016903-z2vqfq98	160	10	followed	follow	VBN
cord-016903-z2vqfq98	160	11	the	the	DT
cord-016903-z2vqfq98	160	12	recommended	recommend	VBN
cord-016903-z2vqfq98	160	13	booster	booster	NN
cord-016903-z2vqfq98	160	14	intervals	interval	NNS
cord-016903-z2vqfq98	160	15	of	of	IN
cord-016903-z2vqfq98	160	16	routine	routine	JJ
cord-016903-z2vqfq98	160	17	immunizations	immunization	NNS
cord-016903-z2vqfq98	160	18	,	,	,
cord-016903-z2vqfq98	160	19	e.g.	e.g.	RB
cord-016903-z2vqfq98	160	20	,	,	,
cord-016903-z2vqfq98	160	21	against	against	IN
cord-016903-z2vqfq98	160	22	tetanus	tetanus	NN
cord-016903-z2vqfq98	160	23	,	,	,
cord-016903-z2vqfq98	160	24	diphtheria	diphtheria	NN
cord-016903-z2vqfq98	160	25	,	,	,
cord-016903-z2vqfq98	160	26	poliomyelitis	poliomyelitis	NN
cord-016903-z2vqfq98	160	27	,	,	,
cord-016903-z2vqfq98	160	28	measles	measle	NNS
cord-016903-z2vqfq98	160	29	or	or	CC
cord-016903-z2vqfq98	160	30	influenza	influenza	NN
cord-016903-z2vqfq98	160	31	.	.	.
cord-016903-z2vqfq98	161	1	TBE	TBE	NNP
cord-016903-z2vqfq98	161	2	is	be	VBZ
cord-016903-z2vqfq98	161	3	caused	cause	VBN
cord-016903-z2vqfq98	161	4	by	by	IN
cord-016903-z2vqfq98	161	5	a	a	DT
cord-016903-z2vqfq98	161	6	virus	virus	NN
cord-016903-z2vqfq98	161	7	that	that	WDT
cord-016903-z2vqfq98	161	8	is	be	VBZ
cord-016903-z2vqfq98	161	9	primarily	primarily	RB
cord-016903-z2vqfq98	161	10	transmitted	transmit	VBN
cord-016903-z2vqfq98	161	11	to	to	IN
cord-016903-z2vqfq98	161	12	humans	human	NNS
cord-016903-z2vqfq98	161	13	by	by	IN
cord-016903-z2vqfq98	161	14	infected	infected	JJ
cord-016903-z2vqfq98	161	15	ticks	tick	NNS
cord-016903-z2vqfq98	161	16	.	.	.
cord-016903-z2vqfq98	162	1	There	there	EX
cord-016903-z2vqfq98	162	2	are	be	VBP
cord-016903-z2vqfq98	162	3	three	three	CD
cord-016903-z2vqfq98	162	4	genetically	genetically	RB
cord-016903-z2vqfq98	162	5	closely	closely	RB
cord-016903-z2vqfq98	162	6	related	related	JJ
cord-016903-z2vqfq98	162	7	subtypes	subtype	NNS
cord-016903-z2vqfq98	162	8	of	of	IN
cord-016903-z2vqfq98	162	9	the	the	DT
cord-016903-z2vqfq98	162	10	TBE	TBE	NNP
cord-016903-z2vqfq98	162	11	virus	virus	NN
cord-016903-z2vqfq98	162	12	known	know	VBN
cord-016903-z2vqfq98	162	13	(	(	-LRB-
cord-016903-z2vqfq98	162	14	European	european	JJ
cord-016903-z2vqfq98	162	15	,	,	,
cord-016903-z2vqfq98	162	16	Siberian	siberian	JJ
cord-016903-z2vqfq98	162	17	and	and	CC
cord-016903-z2vqfq98	162	18	Far	far	JJ
cord-016903-z2vqfq98	162	19	Eastern	eastern	JJ
cord-016903-z2vqfq98	162	20	subtype	subtype	NN
cord-016903-z2vqfq98	162	21	)	)	-RRB-
cord-016903-z2vqfq98	162	22	.	.	.
cord-016903-z2vqfq98	163	1	TBE	TBE	NNP
cord-016903-z2vqfq98	163	2	is	be	VBZ
cord-016903-z2vqfq98	163	3	among	among	IN
cord-016903-z2vqfq98	163	4	the	the	DT
cord-016903-z2vqfq98	163	5	most	most	RBS
cord-016903-z2vqfq98	163	6	dangerous	dangerous	JJ
cord-016903-z2vqfq98	163	7	neuro	neuro	JJ
cord-016903-z2vqfq98	163	8	-	-	HYPH
cord-016903-z2vqfq98	163	9	infectious	infectious	JJ
cord-016903-z2vqfq98	163	10	diseases	disease	NNS
cord-016903-z2vqfq98	163	11	in	in	IN
cord-016903-z2vqfq98	163	12	Europe	Europe	NNP
cord-016903-z2vqfq98	163	13	and	and	CC
cord-016903-z2vqfq98	163	14	Asia	Asia	NNP
cord-016903-z2vqfq98	163	15	and	and	CC
cord-016903-z2vqfq98	163	16	is	be	VBZ
cord-016903-z2vqfq98	163	17	responsible	responsible	JJ
cord-016903-z2vqfq98	163	18	for	for	IN
cord-016903-z2vqfq98	163	19	up	up	IN
cord-016903-z2vqfq98	163	20	to	to	TO
cord-016903-z2vqfq98	163	21	12,000	12,000	CD
cord-016903-z2vqfq98	163	22	casesofTBE	casesoftbe	NN
cord-016903-z2vqfq98	163	23	annually	annually	RB
cord-016903-z2vqfq98	163	24	,	,	,
cord-016903-z2vqfq98	163	25	most	most	JJS
cord-016903-z2vqfq98	163	26	ofthem	ofthem	NNS
cord-016903-z2vqfq98	163	27	occurring	occur	VBG
cord-016903-z2vqfq98	163	28	in	in	IN
cord-016903-z2vqfq98	163	29	Russia	Russia	NNP
cord-016903-z2vqfq98	163	30	,	,	,
cord-016903-z2vqfq98	163	31	Czech	Czech	NNP
cord-016903-z2vqfq98	163	32	Republic	Republic	NNP
cord-016903-z2vqfq98	163	33	and	and	CC
cord-016903-z2vqfq98	163	34	the	the	DT
cord-016903-z2vqfq98	163	35	Baltic	baltic	JJ
cord-016903-z2vqfq98	163	36	states	state	NNS
cord-016903-z2vqfq98	163	37	.	.	.
cord-016903-z2vqfq98	164	1	"	"	``
cord-016903-z2vqfq98	164	2	Up	up	IN
cord-016903-z2vqfq98	164	3	to	to	TO
cord-016903-z2vqfq98	164	4	30	30	CD
cord-016903-z2vqfq98	164	5	%	%	NN
cord-016903-z2vqfq98	164	6	ofadults	ofadult	NNS
cord-016903-z2vqfq98	164	7	with	with	IN
cord-016903-z2vqfq98	164	8	clinically	clinically	RB
cord-016903-z2vqfq98	164	9	confirmed	confirm	VBN
cord-016903-z2vqfq98	164	10	TBE	tbe	NN
cord-016903-z2vqfq98	164	11	infection	infection	NN
cord-016903-z2vqfq98	164	12	develop	develop	VBP
cord-016903-z2vqfq98	164	13	meningitis	meningitis	NN
cord-016903-z2vqfq98	164	14	or	or	CC
cord-016903-z2vqfq98	164	15	meningoencephalitis	meningoencephalitis	NN
cord-016903-z2vqfq98	164	16	and	and	CC
cord-016903-z2vqfq98	164	17	the	the	DT
cord-016903-z2vqfq98	164	18	lethality	lethality	NN
cord-016903-z2vqfq98	164	19	ofTBE	oftbe	XX
cord-016903-z2vqfq98	165	1	in	in	IN
cord-016903-z2vqfq98	165	2	Europe	Europe	NNP
cord-016903-z2vqfq98	165	3	is	be	VBZ
cord-016903-z2vqfq98	165	4	up	up	IN
cord-016903-z2vqfq98	165	5	to	to	IN
cord-016903-z2vqfq98	165	6	1%.Yet	1%.yet	CD
cord-016903-z2vqfq98	165	7	,	,	,
cord-016903-z2vqfq98	165	8	there	there	EX
cord-016903-z2vqfq98	165	9	is	be	VBZ
cord-016903-z2vqfq98	165	10	no	no	DT
cord-016903-z2vqfq98	165	11	specific	specific	JJ
cord-016903-z2vqfq98	165	12	therapy	therapy	NN
cord-016903-z2vqfq98	165	13	available	available	JJ
cord-016903-z2vqfq98	165	14	and	and	CC
cord-016903-z2vqfq98	165	15	,	,	,
cord-016903-z2vqfq98	165	16	therefore	therefore	RB
cord-016903-z2vqfq98	165	17	,	,	,
cord-016903-z2vqfq98	165	18	active	active	JJ
cord-016903-z2vqfq98	165	19	immunization	immunization	NN
cord-016903-z2vqfq98	165	20	with	with	IN
cord-016903-z2vqfq98	165	21	inactivated	inactivate	VBN
cord-016903-z2vqfq98	165	22	whole	whole	JJ
cord-016903-z2vqfq98	165	23	virus	virus	NN
cord-016903-z2vqfq98	165	24	provides	provide	VBZ
cord-016903-z2vqfq98	165	25	the	the	DT
cord-016903-z2vqfq98	165	26	only	only	JJ
cord-016903-z2vqfq98	165	27	efficient	efficient	JJ
cord-016903-z2vqfq98	165	28	protection	protection	NN
cord-016903-z2vqfq98	165	29	from	from	IN
cord-016903-z2vqfq98	165	30	TBE	TBE	NNP
cord-016903-z2vqfq98	165	31	disease	disease	NN
cord-016903-z2vqfq98	165	32	(	(	-LRB-
cord-016903-z2vqfq98	165	33	Table	table	NN
cord-016903-z2vqfq98	165	34	2	2	CD
cord-016903-z2vqfq98	165	35	)	)	-RRB-
cord-016903-z2vqfq98	165	36	.52	.52	.
cord-016903-z2vqfq98	166	1	Importantly	importantly	RB
cord-016903-z2vqfq98	166	2	,	,	,
cord-016903-z2vqfq98	166	3	more	more	JJR
cord-016903-z2vqfq98	166	4	and	and	CC
cord-016903-z2vqfq98	166	5	more	more	JJR
cord-016903-z2vqfq98	166	6	TBE	TBE	NNP
cord-016903-z2vqfq98	166	7	cases	case	NNS
cord-016903-z2vqfq98	166	8	are	be	VBP
cord-016903-z2vqfq98	166	9	reported	report	VBN
cord-016903-z2vqfq98	166	10	in	in	IN
cord-016903-z2vqfq98	166	11	people	people	NNS
cord-016903-z2vqfq98	166	12	over	over	IN
cord-016903-z2vqfq98	166	13	50	50	CD
cord-016903-z2vqfq98	166	14	years	year	NNS
cord-016903-z2vqfq98	166	15	ofage	ofage	JJ
cord-016903-z2vqfq98	166	16	and	and	CC
cord-016903-z2vqfq98	166	17	vaccination	vaccination	NN
cord-016903-z2vqfq98	166	18	coverage	coverage	NN
cord-016903-z2vqfq98	166	19	in	in	IN
cord-016903-z2vqfq98	166	20	this	this	DT
cord-016903-z2vqfq98	166	21	population	population	NN
cord-016903-z2vqfq98	166	22	is	be	VBZ
cord-016903-z2vqfq98	166	23	lower	low	JJR
cord-016903-z2vqfq98	166	24	than	than	IN
cord-016903-z2vqfq98	166	25	average	average	JJ
cord-016903-z2vqfq98	166	26	.	.	.
cord-016903-z2vqfq98	167	1	Therefore	therefore	RB
cord-016903-z2vqfq98	167	2	,	,	,
cord-016903-z2vqfq98	167	3	future	future	JJ
cord-016903-z2vqfq98	167	4	strategies	strategy	NNS
cord-016903-z2vqfq98	167	5	should	should	MD
cord-016903-z2vqfq98	167	6	increase	increase	VB
cord-016903-z2vqfq98	167	7	the	the	DT
cord-016903-z2vqfq98	167	8	vaccination	vaccination	NN
cord-016903-z2vqfq98	167	9	coverage	coverage	NN
cord-016903-z2vqfq98	167	10	among	among	IN
cord-016903-z2vqfq98	167	11	elderly	elderly	JJ
cord-016903-z2vqfq98	167	12	persons	person	NNS
cord-016903-z2vqfq98	167	13	and	and	CC
cord-016903-z2vqfq98	167	14	assure	assure	VB
cord-016903-z2vqfq98	167	15	that	that	IN
cord-016903-z2vqfq98	167	16	they	-PRON-	PRP
cord-016903-z2vqfq98	167	17	stick	stick	VBP
cord-016903-z2vqfq98	167	18	to	to	IN
cord-016903-z2vqfq98	167	19	regular	regular	JJ
cord-016903-z2vqfq98	167	20	booster	booster	NN
cord-016903-z2vqfq98	167	21	intervals	interval	NNS
cord-016903-z2vqfq98	167	22	.	.	.
cord-016903-z2vqfq98	168	1	Anyhow	anyhow	RB
cord-016903-z2vqfq98	168	2	,	,	,
cord-016903-z2vqfq98	168	3	regular	regular	JJ
cord-016903-z2vqfq98	168	4	boosters	booster	NNS
cord-016903-z2vqfq98	168	5	should	should	MD
cord-016903-z2vqfq98	168	6	be	be	VB
cord-016903-z2vqfq98	168	7	given	give	VBN
cord-016903-z2vqfq98	168	8	throughout	throughout	IN
cord-016903-z2vqfq98	168	9	life	life	NN
cord-016903-z2vqfq98	168	10	as	as	IN
cord-016903-z2vqfq98	168	11	this	this	DT
cord-016903-z2vqfq98	168	12	may	may	MD
cord-016903-z2vqfq98	168	13	favor	favor	VB
cord-016903-z2vqfq98	168	14	the	the	DT
cord-016903-z2vqfq98	168	15	maintenance	maintenance	NN
cord-016903-z2vqfq98	168	16	oflong	oflong	NN
cord-016903-z2vqfq98	168	17	-	-	HYPH
cord-016903-z2vqfq98	168	18	lastinghumoral	lastinghumoral	JJ
cord-016903-z2vqfq98	168	19	immunity	immunity	NN
cord-016903-z2vqfq98	168	20	against	against	IN
cord-016903-z2vqfq98	168	21	TBE53and	TBE53and	NNP
cord-016903-z2vqfq98	168	22	may	may	MD
cord-016903-z2vqfq98	168	23	decrease	decrease	VB
cord-016903-z2vqfq98	168	24	the	the	DT
cord-016903-z2vqfq98	168	25	risk	risk	NN
cord-016903-z2vqfq98	168	26	ofimmunization	ofimmunization	NN
cord-016903-z2vqfq98	168	27	failures	failure	NNS
cord-016903-z2vqfq98	168	28	in	in	IN
cord-016903-z2vqfq98	168	29	the	the	DT
cord-016903-z2vqfq98	168	30	elderly	elderly	JJ
cord-016903-z2vqfq98	168	31	.	.	.
cord-016903-z2vqfq98	169	1	Hepatitis	Hepatitis	NNP
cord-016903-z2vqfq98	169	2	A	A	NNP
cord-016903-z2vqfq98	169	3	is	be	VBZ
cord-016903-z2vqfq98	169	4	an	an	DT
cord-016903-z2vqfq98	169	5	acute	acute	JJ
cord-016903-z2vqfq98	169	6	disease	disease	NN
cord-016903-z2vqfq98	169	7	ofthe	ofthe	DT
cord-016903-z2vqfq98	169	8	liver	liver	NN
cord-016903-z2vqfq98	169	9	caused	cause	VBN
cord-016903-z2vqfq98	169	10	by	by	IN
cord-016903-z2vqfq98	169	11	the	the	DT
cord-016903-z2vqfq98	169	12	hepatitis	hepatitis	NN
cord-016903-z2vqfq98	169	13	A	A	NNP
cord-016903-z2vqfq98	169	14	virus	virus	NN
cord-016903-z2vqfq98	169	15	(	(	-LRB-
cord-016903-z2vqfq98	169	16	HAY	HAY	NNP
cord-016903-z2vqfq98	169	17	)	)	-RRB-
cord-016903-z2vqfq98	169	18	,	,	,
cord-016903-z2vqfq98	169	19	a	a	DT
cord-016903-z2vqfq98	169	20	nonenveloped	nonenveloped	JJ
cord-016903-z2vqfq98	169	21	virus	virus	NN
cord-016903-z2vqfq98	169	22	belonging	belong	VBG
cord-016903-z2vqfq98	169	23	to	to	IN
cord-016903-z2vqfq98	169	24	the	the	DT
cord-016903-z2vqfq98	169	25	Picornaviridae	Picornaviridae	NNP
cord-016903-z2vqfq98	169	26	family	family	NN
cord-016903-z2vqfq98	169	27	.	.	.
cord-016903-z2vqfq98	170	1	Each	each	DT
cord-016903-z2vqfq98	170	2	year	year	NN
cord-016903-z2vqfq98	170	3	,	,	,
cord-016903-z2vqfq98	170	4	an	an	DT
cord-016903-z2vqfq98	170	5	estimated	estimate	VBN
cord-016903-z2vqfq98	170	6	1.5	1.5	CD
cord-016903-z2vqfq98	170	7	million	million	CD
cord-016903-z2vqfq98	170	8	cases	case	NNS
cord-016903-z2vqfq98	170	9	ofhepatitis	ofhepatitis	VBP
cord-016903-z2vqfq98	170	10	A	a	DT
cord-016903-z2vqfq98	170	11	occur	occur	VBP
cord-016903-z2vqfq98	170	12	worldwide	worldwide	RB
cord-016903-z2vqfq98	170	13	.	.	.
cord-016903-z2vqfq98	171	1	HAY	HAY	NNP
cord-016903-z2vqfq98	171	2	infection	infection	NN
cord-016903-z2vqfq98	171	3	induces	induce	VBZ
cord-016903-z2vqfq98	171	4	life	life	NN
cord-016903-z2vqfq98	171	5	-	-	HYPH
cord-016903-z2vqfq98	171	6	long	long	JJ
cord-016903-z2vqfq98	171	7	immunity	immunity	NN
cord-016903-z2vqfq98	171	8	and	and	CC
cord-016903-z2vqfq98	171	9	is	be	VBZ
cord-016903-z2vqfq98	171	10	usually	usually	RB
cord-016903-z2vqfq98	171	11	asymptomatic	asymptomatic	JJ
cord-016903-z2vqfq98	171	12	in	in	IN
cord-016903-z2vqfq98	171	13	young	young	JJ
cord-016903-z2vqfq98	171	14	children	child	NNS
cord-016903-z2vqfq98	171	15	,	,	,
cord-016903-z2vqfq98	171	16	whereas	whereas	IN
cord-016903-z2vqfq98	171	17	adults	adult	NNS
cord-016903-z2vqfq98	171	18	frequently	frequently	RB
cord-016903-z2vqfq98	171	19	experience	experience	VBP
cord-016903-z2vqfq98	171	20	symptomatic	symptomatic	JJ
cord-016903-z2vqfq98	171	21	disease	disease	NN
cord-016903-z2vqfq98	171	22	.	.	.
cord-016903-z2vqfq98	172	1	HAY	HAY	NNP
cord-016903-z2vqfq98	172	2	is	be	VBZ
cord-016903-z2vqfq98	172	3	acquired	acquire	VBN
cord-016903-z2vqfq98	172	4	directly	directly	RB
cord-016903-z2vqfq98	172	5	from	from	IN
cord-016903-z2vqfq98	172	6	infected	infected	JJ
cord-016903-z2vqfq98	172	7	persons	person	NNS
cord-016903-z2vqfq98	172	8	by	by	IN
cord-016903-z2vqfq98	172	9	close	close	JJ
cord-016903-z2vqfq98	172	10	contact	contact	NN
cord-016903-z2vqfq98	172	11	or	or	CC
cord-016903-z2vqfq98	172	12	by	by	IN
cord-016903-z2vqfq98	172	13	the	the	DT
cord-016903-z2vqfq98	172	14	consumption	consumption	NN
cord-016903-z2vqfq98	172	15	ofcontaminated	ofcontaminate	VBN
cord-016903-z2vqfq98	172	16	drinking	drinking	NN
cord-016903-z2vqfq98	172	17	water	water	NN
cord-016903-z2vqfq98	172	18	,	,	,
cord-016903-z2vqfq98	172	19	vegetables	vegetable	NNS
cord-016903-z2vqfq98	172	20	,	,	,
cord-016903-z2vqfq98	172	21	fruits	fruit	NNS
cord-016903-z2vqfq98	172	22	or	or	CC
cord-016903-z2vqfq98	172	23	shells	shell	NNS
cord-016903-z2vqfq98	172	24	.	.	.
cord-016903-z2vqfq98	173	1	HAY	HAY	NNP
cord-016903-z2vqfq98	173	2	vaccination	vaccination	NN
cord-016903-z2vqfq98	173	3	is	be	VBZ
cord-016903-z2vqfq98	173	4	recommended	recommend	VBN
cord-016903-z2vqfq98	173	5	when	when	WRB
cord-016903-z2vqfq98	173	6	traveling	travel	VBG
cord-016903-z2vqfq98	173	7	to	to	IN
cord-016903-z2vqfq98	173	8	tropic	tropic	NNP
cord-016903-z2vqfq98	173	9	and	and	CC
cord-016903-z2vqfq98	173	10	subtropic	subtropic	NNP
cord-016903-z2vqfq98	173	11	countries	country	NNS
cord-016903-z2vqfq98	173	12	that	that	WDT
cord-016903-z2vqfq98	173	13	have	have	VBP
cord-016903-z2vqfq98	173	14	an	an	DT
cord-016903-z2vqfq98	173	15	increased	increase	VBN
cord-016903-z2vqfq98	173	16	risk	risk	NN
cord-016903-z2vqfq98	173	17	of	of	IN
cord-016903-z2vqfq98	173	18	infection	infection	NN
cord-016903-z2vqfq98	173	19	.	.	.
cord-016903-z2vqfq98	174	1	For	for	IN
cord-016903-z2vqfq98	174	2	instance	instance	NN
cord-016903-z2vqfq98	174	3	,	,	,
cord-016903-z2vqfq98	174	4	the	the	DT
cord-016903-z2vqfq98	174	5	risk	risk	NN
cord-016903-z2vqfq98	174	6	ofhepatitis	ofhepatitis	NN
cord-016903-z2vqfq98	174	7	A	a	DT
cord-016903-z2vqfq98	174	8	infection	infection	NN
cord-016903-z2vqfq98	174	9	ofpersons	ofperson	NNS
cord-016903-z2vqfq98	174	10	traveling	travel	VBG
cord-016903-z2vqfq98	174	11	to	to	IN
cord-016903-z2vqfq98	174	12	developing	develop	VBG
cord-016903-z2vqfq98	174	13	countries	country	NNS
cord-016903-z2vqfq98	174	14	was	be	VBD
cord-016903-z2vqfq98	174	15	estimated	estimate	VBN
cord-016903-z2vqfq98	174	16	to	to	TO
cord-016903-z2vqfq98	174	17	be	be	VB
cord-016903-z2vqfq98	174	18	3	3	CD
cord-016903-z2vqfq98	174	19	to	to	TO
cord-016903-z2vqfq98	174	20	20	20	CD
cord-016903-z2vqfq98	174	21	cases	case	NNS
cord-016903-z2vqfq98	174	22	per	per	IN
cord-016903-z2vqfq98	174	23	1000	1000	CD
cord-016903-z2vqfq98	174	24	persons	person	NNS
cord-016903-z2vqfq98	174	25	per	per	IN
cord-016903-z2vqfq98	174	26	month	month	NN
cord-016903-z2vqfq98	174	27	ofstay	ofstay	NN
cord-016903-z2vqfq98	174	28	,	,	,
cord-016903-z2vqfq98	174	29	varying	vary	VBG
cord-016903-z2vqfq98	174	30	with	with	IN
cord-016903-z2vqfq98	174	31	destination	destination	NN
cord-016903-z2vqfq98	174	32	,	,	,
cord-016903-z2vqfq98	174	33	living	living	NN
cord-016903-z2vqfq98	174	34	conditions	condition	NNS
cord-016903-z2vqfq98	174	35	and	and	CC
cord-016903-z2vqfq98	174	36	age	age	NN
cord-016903-z2vqfq98	174	37	.	.	.
cord-016903-z2vqfq98	174	38	"	"	''
cord-016903-z2vqfq98	175	1	Improved	improve	VBN
cord-016903-z2vqfq98	175	2	sanitary	sanitary	JJ
cord-016903-z2vqfq98	175	3	standards	standard	NNS
cord-016903-z2vqfq98	175	4	in	in	IN
cord-016903-z2vqfq98	175	5	developed	develop	VBN
cord-016903-z2vqfq98	175	6	countries	country	NNS
cord-016903-z2vqfq98	175	7	have	have	VBP
cord-016903-z2vqfq98	175	8	reduced	reduce	VBN
cord-016903-z2vqfq98	175	9	the	the	DT
cord-016903-z2vqfq98	175	10	opportunity	opportunity	NN
cord-016903-z2vqfq98	175	11	for	for	IN
cord-016903-z2vqfq98	175	12	environmental	environmental	JJ
cord-016903-z2vqfq98	175	13	exposure	exposure	NN
cord-016903-z2vqfq98	175	14	to	to	IN
cord-016903-z2vqfq98	175	15	HAY	HAY	NNP
cord-016903-z2vqfq98	175	16	and	and	CC
cord-016903-z2vqfq98	175	17	have	have	VBP
cord-016903-z2vqfq98	175	18	lowered	lower	VBN
cord-016903-z2vqfq98	175	19	the	the	DT
cord-016903-z2vqfq98	175	20	overall	overall	JJ
cord-016903-z2vqfq98	175	21	incidence	incidence	NN
cord-016903-z2vqfq98	175	22	ofinfection	ofinfection	NN
cord-016903-z2vqfq98	175	23	.	.	.
cord-016903-z2vqfq98	176	1	Paradoxically	paradoxically	RB
cord-016903-z2vqfq98	176	2	,	,	,
cord-016903-z2vqfq98	176	3	susceptibility	susceptibility	NN
cord-016903-z2vqfq98	176	4	to	to	IN
cord-016903-z2vqfq98	176	5	the	the	DT
cord-016903-z2vqfq98	176	6	virus	virus	NN
cord-016903-z2vqfq98	176	7	increased	increase	VBN
cord-016903-z2vqfq98	176	8	because	because	IN
cord-016903-z2vqfq98	176	9	of	of	IN
cord-016903-z2vqfq98	176	10	the	the	DT
cord-016903-z2vqfq98	176	11	decrease	decrease	NN
cord-016903-z2vqfq98	176	12	in	in	IN
cord-016903-z2vqfq98	176	13	natural	natural	JJ
cord-016903-z2vqfq98	176	14	immunity	immunity	NN
cord-016903-z2vqfq98	176	15	.	.	.
cord-016903-z2vqfq98	177	1	Consequently	consequently	RB
cord-016903-z2vqfq98	177	2	,	,	,
cord-016903-z2vqfq98	177	3	less	less	JJR
cord-016903-z2vqfq98	177	4	than	than	IN
cord-016903-z2vqfq98	177	5	20	20	CD
cord-016903-z2vqfq98	177	6	%	%	NN
cord-016903-z2vqfq98	177	7	ofpersons	ofperson	NNS
cord-016903-z2vqfq98	177	8	born	bear	VBN
cord-016903-z2vqfq98	177	9	after	after	IN
cord-016903-z2vqfq98	177	10	1945	1945	CD
cord-016903-z2vqfq98	177	11	have	have	VBP
cord-016903-z2vqfq98	177	12	a	a	DT
cord-016903-z2vqfq98	177	13	natural	natural	JJ
cord-016903-z2vqfq98	177	14	immunity	immunity	NN
cord-016903-z2vqfq98	177	15	against	against	IN
cord-016903-z2vqfq98	177	16	HAy'54	HAy'54	NNP
cord-016903-z2vqfq98	178	1	In	in	IN
cord-016903-z2vqfq98	178	2	contrast	contrast	NN
cord-016903-z2vqfq98	178	3	to	to	IN
cord-016903-z2vqfq98	178	4	hepatitis	hepatitis	NNP
cord-016903-z2vqfq98	178	5	B	B	NNP
cord-016903-z2vqfq98	178	6	and	and	CC
cord-016903-z2vqfq98	178	7	C	C	NNP
cord-016903-z2vqfq98	178	8	that	that	WDT
cord-016903-z2vqfq98	178	9	may	may	MD
cord-016903-z2vqfq98	178	10	lead	lead	VB
cord-016903-z2vqfq98	178	11	to	to	IN
cord-016903-z2vqfq98	178	12	the	the	DT
cord-016903-z2vqfq98	178	13	manifestation	manifestation	NN
cord-016903-z2vqfq98	178	14	of	of	IN
cord-016903-z2vqfq98	178	15	a	a	DT
cord-016903-z2vqfq98	178	16	chronic	chronic	JJ
cord-016903-z2vqfq98	178	17	infection	infection	NN
cord-016903-z2vqfq98	178	18	,	,	,
cord-016903-z2vqfq98	178	19	clinical	clinical	JJ
cord-016903-z2vqfq98	178	20	illness	illness	NN
cord-016903-z2vqfq98	178	21	after	after	IN
cord-016903-z2vqfq98	178	22	hepatitis	hepatitis	NNP
cord-016903-z2vqfq98	178	23	A	a	DT
cord-016903-z2vqfq98	178	24	infection	infection	NN
cord-016903-z2vqfq98	178	25	is	be	VBZ
cord-016903-z2vqfq98	178	26	usually	usually	RB
cord-016903-z2vqfq98	178	27	mild	mild	JJ
cord-016903-z2vqfq98	178	28	in	in	IN
cord-016903-z2vqfq98	178	29	young	young	JJ
cord-016903-z2vqfq98	178	30	individuals	individual	NNS
cord-016903-z2vqfq98	178	31	.	.	.
cord-016903-z2vqfq98	179	1	But	but	CC
cord-016903-z2vqfq98	179	2	increasing	increase	VBG
cord-016903-z2vqfq98	179	3	age	age	NN
cord-016903-z2vqfq98	179	4	represents	represent	VBZ
cord-016903-z2vqfq98	179	5	an	an	DT
cord-016903-z2vqfq98	179	6	enhanced	enhanced	JJ
cord-016903-z2vqfq98	179	7	risk	risk	NN
cord-016903-z2vqfq98	179	8	ofsevere	ofsevere	JJ
cord-016903-z2vqfq98	179	9	infection	infection	NN
cord-016903-z2vqfq98	179	10	and	and	CC
cord-016903-z2vqfq98	179	11	mortality	mortality	NN
cord-016903-z2vqfq98	179	12	rates	rate	NNS
cord-016903-z2vqfq98	179	13	are	be	VBP
cord-016903-z2vqfq98	179	14	about	about	RB
cord-016903-z2vqfq98	179	15	2	2	CD
cord-016903-z2vqfq98	179	16	%	%	NN
cord-016903-z2vqfq98	179	17	for	for	IN
cord-016903-z2vqfq98	179	18	persons	person	NNS
cord-016903-z2vqfq98	179	19	over	over	IN
cord-016903-z2vqfq98	179	20	40	40	CD
cord-016903-z2vqfq98	179	21	and	and	CC
cord-016903-z2vqfq98	179	22	4	4	CD
cord-016903-z2vqfq98	179	23	%	%	NN
cord-016903-z2vqfq98	179	24	for	for	IN
cord-016903-z2vqfq98	179	25	those	those	DT
cord-016903-z2vqfq98	179	26	over	over	IN
cord-016903-z2vqfq98	179	27	60	60	CD
cord-016903-z2vqfq98	179	28	years	year	NNS
cord-016903-z2vqfq98	179	29	ofage	ofage	JJ
cord-016903-z2vqfq98	179	30	.	.	.
cord-016903-z2vqfq98	179	31	"	"	''
cord-016903-z2vqfq98	180	1	Several	several	JJ
cord-016903-z2vqfq98	180	2	vaccines	vaccine	NNS
cord-016903-z2vqfq98	180	3	against	against	IN
cord-016903-z2vqfq98	180	4	hepatitis	hepatitis	NNP
cord-016903-z2vqfq98	180	5	A	A	NNP
cord-016903-z2vqfq98	180	6	are	be	VBP
cord-016903-z2vqfq98	180	7	available	available	JJ
cord-016903-z2vqfq98	180	8	(	(	-LRB-
cord-016903-z2vqfq98	180	9	Table	table	NN
cord-016903-z2vqfq98	180	10	2	2	CD
cord-016903-z2vqfq98	180	11	)	)	-RRB-
cord-016903-z2vqfq98	180	12	and	and	CC
cord-016903-z2vqfq98	180	13	a	a	DT
cord-016903-z2vqfq98	180	14	study	study	NN
cord-016903-z2vqfq98	180	15	of773	of773	VBP
cord-016903-z2vqfq98	180	16	adults	adult	NNS
cord-016903-z2vqfq98	180	17	showed	show	VBD
cord-016903-z2vqfq98	180	18	that	that	IN
cord-016903-z2vqfq98	180	19	immunogenicity	immunogenicity	NN
cord-016903-z2vqfq98	180	20	and	and	CC
cord-016903-z2vqfq98	180	21	safety	safety	NN
cord-016903-z2vqfq98	180	22	profiles	profile	NNS
cord-016903-z2vqfq98	180	23	between	between	IN
cord-016903-z2vqfq98	180	24	'	'	``
cord-016903-z2vqfq98	180	25	Iwinrix	Iwinrix	NNP
cord-016903-z2vqfq98	180	26	'	'	''
cord-016903-z2vqfq98	180	27	and	and	CC
cord-016903-z2vqfq98	180	28	Havrix	Havrix	NNP
cord-016903-z2vqfq98	180	29	'	'	''
cord-016903-z2vqfq98	180	30	are	be	VBP
cord-016903-z2vqfq98	180	31	comparable.56	comparable.56	NNP
cord-016903-z2vqfq98	181	1	But	but	CC
cord-016903-z2vqfq98	181	2	there	there	EX
cord-016903-z2vqfq98	181	3	is	be	VBZ
cord-016903-z2vqfq98	181	4	some	some	DT
cord-016903-z2vqfq98	181	5	evidence	evidence	NN
cord-016903-z2vqfq98	181	6	oflower	oflow	JJR
cord-016903-z2vqfq98	181	7	antibody	antibody	NN
cord-016903-z2vqfq98	181	8	titers	titer	NNS
cord-016903-z2vqfq98	181	9	with	with	IN
cord-016903-z2vqfq98	181	10	advanced	advanced	JJ
cord-016903-z2vqfq98	181	11	age	age	NN
cord-016903-z2vqfq98	181	12	.	.	.
cord-016903-z2vqfq98	182	1	For	for	IN
cord-016903-z2vqfq98	182	2	instance	instance	NN
cord-016903-z2vqfq98	182	3	,	,	,
cord-016903-z2vqfq98	182	4	the	the	DT
cord-016903-z2vqfq98	182	5	seroconversion	seroconversion	NN
cord-016903-z2vqfq98	182	6	rates	rate	NNS
cord-016903-z2vqfq98	182	7	8	8	CD
cord-016903-z2vqfq98	182	8	months	month	NNS
cord-016903-z2vqfq98	182	9	after	after	IN
cord-016903-z2vqfq98	182	10	two	two	CD
cord-016903-z2vqfq98	182	11	doses	dose	NNS
cord-016903-z2vqfq98	182	12	ofHavrix	ofHavrix	NNP
cord-016903-z2vqfq98	182	13	'	'	''
cord-016903-z2vqfq98	182	14	were	be	VBD
cord-016903-z2vqfq98	182	15	found	find	VBN
cord-016903-z2vqfq98	182	16	to	to	TO
cord-016903-z2vqfq98	182	17	be	be	VB
cord-016903-z2vqfq98	182	18	85	85	CD
cord-016903-z2vqfq98	182	19	%	%	NN
cord-016903-z2vqfq98	182	20	and	and	CC
cord-016903-z2vqfq98	182	21	60	60	CD
cord-016903-z2vqfq98	182	22	%	%	NN
cord-016903-z2vqfq98	182	23	for	for	IN
cord-016903-z2vqfq98	182	24	adults	adult	NNS
cord-016903-z2vqfq98	182	25	<	<	XX
cord-016903-z2vqfq98	182	26	35	35	CD
cord-016903-z2vqfq98	182	27	years	year	NNS
cord-016903-z2vqfq98	182	28	and	and	CC
cord-016903-z2vqfq98	182	29	>	>	SYM
cord-016903-z2vqfq98	182	30	35	35	CD
cord-016903-z2vqfq98	182	31	years	year	NNS
cord-016903-z2vqfq98	182	32	,	,	,
cord-016903-z2vqfq98	182	33	respectively.57After	respectively.57After	.
cord-016903-z2vqfq98	183	1	the	the	DT
cord-016903-z2vqfq98	183	2	recommended	recommend	VBN
cord-016903-z2vqfq98	183	3	immunization	immunization	NN
cord-016903-z2vqfq98	183	4	schedule	schedule	NN
cord-016903-z2vqfq98	183	5	with	with	IN
cord-016903-z2vqfq98	183	6	Twinrix'.seroprotection	twinrix'.seroprotection	NN
cord-016903-z2vqfq98	183	7	was	be	VBD
cord-016903-z2vqfq98	183	8	92	92	CD
cord-016903-z2vqfq98	183	9	%	%	NN
cord-016903-z2vqfq98	183	10	and	and	CC
cord-016903-z2vqfq98	183	11	63	63	CD
cord-016903-z2vqfq98	183	12	%	%	NN
cord-016903-z2vqfq98	183	13	for	for	IN
cord-016903-z2vqfq98	183	14	adults	adult	NNS
cord-016903-z2vqfq98	183	15	<	<	XX
cord-016903-z2vqfq98	183	16	40	40	CD
cord-016903-z2vqfq98	183	17	years	year	NNS
cord-016903-z2vqfq98	183	18	and	and	CC
cord-016903-z2vqfq98	183	19	>	>	XX
cord-016903-z2vqfq98	183	20	60	60	CD
cord-016903-z2vqfq98	183	21	years	year	NNS
cord-016903-z2vqfq98	183	22	,	,	,
cord-016903-z2vqfq98	183	23	respectively.58	respectively.58	JJ
cord-016903-z2vqfq98	184	1	Therefore	therefore	RB
cord-016903-z2vqfq98	184	2	,	,	,
cord-016903-z2vqfq98	184	3	it	-PRON-	PRP
cord-016903-z2vqfq98	184	4	may	may	MD
cord-016903-z2vqfq98	184	5	be	be	VB
cord-016903-z2vqfq98	184	6	useful	useful	JJ
cord-016903-z2vqfq98	184	7	to	to	TO
cord-016903-z2vqfq98	184	8	measure	measure	VB
cord-016903-z2vqfq98	184	9	HAY	HAY	NNP
cord-016903-z2vqfq98	184	10	antibodies	antibody	NNS
cord-016903-z2vqfq98	184	11	in	in	IN
cord-016903-z2vqfq98	184	12	elderly	elderly	JJ
cord-016903-z2vqfq98	184	13	persons	person	NNS
cord-016903-z2vqfq98	184	14	,	,	,
cord-016903-z2vqfq98	184	15	as	as	IN
cord-016903-z2vqfq98	184	16	in	in	IN
cord-016903-z2vqfq98	184	17	the	the	DT
cord-016903-z2vqfq98	184	18	case	case	NN
cord-016903-z2vqfq98	184	19	ofvaccination	ofvaccination	NN
cord-016903-z2vqfq98	184	20	failure	failure	NN
cord-016903-z2vqfq98	184	21	,	,	,
cord-016903-z2vqfq98	184	22	boosters	booster	NNS
cord-016903-z2vqfq98	184	23	have	have	VBP
cord-016903-z2vqfq98	184	24	shown	show	VBN
cord-016903-z2vqfq98	184	25	to	to	TO
cord-016903-z2vqfq98	184	26	be	be	VB
cord-016903-z2vqfq98	184	27	effective	effective	JJ
cord-016903-z2vqfq98	184	28	.	.	.
cord-016903-z2vqfq98	185	1	"	"	``
cord-016903-z2vqfq98	185	2	It	-PRON-	PRP
cord-016903-z2vqfq98	185	3	is	be	VBZ
cord-016903-z2vqfq98	185	4	further	further	RB
cord-016903-z2vqfq98	185	5	recommended	recommend	VBN
cord-016903-z2vqfq98	185	6	that	that	IN
cord-016903-z2vqfq98	185	7	the	the	DT
cord-016903-z2vqfq98	185	8	vaccine	vaccine	NN
cord-016903-z2vqfq98	185	9	is	be	VBZ
cord-016903-z2vqfq98	185	10	given	give	VBN
cord-016903-z2vqfq98	185	11	at	at	IN
cord-016903-z2vqfq98	185	12	least	least	JJS
cord-016903-z2vqfq98	185	13	3	3	CD
cord-016903-z2vqfq98	185	14	to	to	TO
cord-016903-z2vqfq98	185	15	4	4	CD
cord-016903-z2vqfq98	185	16	weeks	week	NNS
cord-016903-z2vqfq98	185	17	before	before	IN
cord-016903-z2vqfq98	185	18	travel	travel	NN
cord-016903-z2vqfq98	185	19	due	due	IN
cord-016903-z2vqfq98	185	20	to	to	IN
cord-016903-z2vqfq98	185	21	a	a	DT
cord-016903-z2vqfq98	185	22	slower	slow	JJR
cord-016903-z2vqfq98	185	23	onset	onset	NN
cord-016903-z2vqfq98	185	24	ofthe	ofthe	DT
cord-016903-z2vqfq98	185	25	antibody	antibody	NN
cord-016903-z2vqfq98	185	26	response	response	NN
cord-016903-z2vqfq98	185	27	in	in	IN
cord-016903-z2vqfq98	185	28	elderly	elderly	JJ
cord-016903-z2vqfq98	185	29	individuals	individual	NNS
cord-016903-z2vqfq98	185	30	.	.	.
cord-016903-z2vqfq98	186	1	59	59	CD
cord-016903-z2vqfq98	187	1	Another	another	DT
cord-016903-z2vqfq98	187	2	travel	travel	NN
cord-016903-z2vqfq98	187	3	vaccine	vaccine	NN
cord-016903-z2vqfq98	187	4	is	be	VBZ
cord-016903-z2vqfq98	187	5	directed	direct	VBN
cord-016903-z2vqfq98	187	6	against	against	IN
cord-016903-z2vqfq98	187	7	yellow	yellow	JJ
cord-016903-z2vqfq98	187	8	fever	fever	NN
cord-016903-z2vqfq98	187	9	(	(	-LRB-
cord-016903-z2vqfq98	187	10	YF	YF	NNP
cord-016903-z2vqfq98	187	11	)	)	-RRB-
cord-016903-z2vqfq98	187	12	,	,	,
cord-016903-z2vqfq98	187	13	which	which	WDT
cord-016903-z2vqfq98	187	14	is	be	VBZ
cord-016903-z2vqfq98	187	15	endemic	endemic	JJ
cord-016903-z2vqfq98	187	16	in	in	IN
cord-016903-z2vqfq98	187	17	tropic	tropic	NN
cord-016903-z2vqfq98	187	18	regions	region	NNS
cord-016903-z2vqfq98	187	19	ofAfrica	ofAfrica	NNP
cord-016903-z2vqfq98	187	20	and	and	CC
cord-016903-z2vqfq98	187	21	South	South	NNP
cord-016903-z2vqfq98	187	22	America	America	NNP
cord-016903-z2vqfq98	187	23	.	.	.
cord-016903-z2vqfq98	188	1	YF	YF	NNP
cord-016903-z2vqfq98	188	2	is	be	VBZ
cord-016903-z2vqfq98	188	3	transmitted	transmit	VBN
cord-016903-z2vqfq98	188	4	by	by	IN
cord-016903-z2vqfq98	188	5	the	the	DT
cord-016903-z2vqfq98	188	6	bite	bite	NN
cord-016903-z2vqfq98	188	7	ofinfective	ofinfective	JJ
cord-016903-z2vqfq98	188	8	Aedes	Aedes	NNP
cord-016903-z2vqfq98	188	9	aegypti	aegypti	NN
cord-016903-z2vqfq98	188	10	and	and	CC
cord-016903-z2vqfq98	188	11	other	other	JJ
cord-016903-z2vqfq98	188	12	mosquitoes	mosquito	NNS
cord-016903-z2vqfq98	188	13	that	that	WDT
cord-016903-z2vqfq98	188	14	bite	bite	VBP
cord-016903-z2vqfq98	188	15	during	during	IN
cord-016903-z2vqfq98	188	16	daylight	daylight	NN
cord-016903-z2vqfq98	188	17	hours	hour	NNS
cord-016903-z2vqfq98	188	18	in	in	IN
cord-016903-z2vqfq98	188	19	regions	region	NNS
cord-016903-z2vqfq98	188	20	below	below	IN
cord-016903-z2vqfq98	188	21	2500	2500	CD
cord-016903-z2vqfq98	188	22	meters	meter	NNS
cord-016903-z2vqfq98	188	23	ofaltitude	ofaltitude	NN
cord-016903-z2vqfq98	188	24	.	.	.
cord-016903-z2vqfq98	189	1	Most	Most	JJS
cord-016903-z2vqfq98	189	2	infections	infection	NNS
cord-016903-z2vqfq98	189	3	lead	lead	VBP
cord-016903-z2vqfq98	189	4	to	to	IN
cord-016903-z2vqfq98	189	5	an	an	DT
cord-016903-z2vqfq98	189	6	acute	acute	JJ
cord-016903-z2vqfq98	189	7	illness	illness	NN
cord-016903-z2vqfq98	189	8	characterized	characterize	VBN
cord-016903-z2vqfq98	189	9	by	by	IN
cord-016903-z2vqfq98	189	10	fever	fever	NN
cord-016903-z2vqfq98	189	11	,	,	,
cord-016903-z2vqfq98	189	12	muscular	muscular	JJ
cord-016903-z2vqfq98	189	13	pain	pain	NN
cord-016903-z2vqfq98	189	14	,	,	,
cord-016903-z2vqfq98	189	15	headache	headache	NN
cord-016903-z2vqfq98	189	16	,	,	,
cord-016903-z2vqfq98	189	17	anorexia	anorexia	NN
cord-016903-z2vqfq98	189	18	,	,	,
cord-016903-z2vqfq98	189	19	nausea	nausea	NN
cord-016903-z2vqfq98	189	20	and/or	and/or	CC
cord-016903-z2vqfq98	189	21	vomiting	vomiting	NN
cord-016903-z2vqfq98	189	22	,	,	,
cord-016903-z2vqfq98	189	23	often	often	RB
cord-016903-z2vqfq98	189	24	with	with	IN
cord-016903-z2vqfq98	189	25	bradycardia	bradycardia	NN
cord-016903-z2vqfq98	189	26	.	.	.
cord-016903-z2vqfq98	190	1	After	after	IN
cord-016903-z2vqfq98	190	2	a	a	DT
cord-016903-z2vqfq98	190	3	few	few	JJ
cord-016903-z2vqfq98	190	4	days	day	NNS
cord-016903-z2vqfq98	190	5	,	,	,
cord-016903-z2vqfq98	190	6	about	about	RB
cord-016903-z2vqfq98	190	7	15	15	CD
cord-016903-z2vqfq98	190	8	%	%	NN
cord-016903-z2vqfq98	190	9	ofpatients	ofpatient	NNS
cord-016903-z2vqfq98	190	10	progress	progress	NN
cord-016903-z2vqfq98	190	11	to	to	IN
cord-016903-z2vqfq98	190	12	a	a	DT
cord-016903-z2vqfq98	190	13	second	second	JJ
cord-016903-z2vqfq98	190	14	phase	phase	NN
cord-016903-z2vqfq98	190	15	,	,	,
cord-016903-z2vqfq98	190	16	with	with	IN
cord-016903-z2vqfq98	190	17	resurgence	resurgence	NN
cord-016903-z2vqfq98	190	18	offever	offever	RB
cord-016903-z2vqfq98	190	19	,	,	,
cord-016903-z2vqfq98	190	20	development	development	NN
cord-016903-z2vqfq98	190	21	ofjaundice	ofjaundice	NN
cord-016903-z2vqfq98	190	22	,	,	,
cord-016903-z2vqfq98	190	23	abdominal	abdominal	JJ
cord-016903-z2vqfq98	190	24	pain	pain	NN
cord-016903-z2vqfq98	190	25	and	and	CC
cord-016903-z2vqfq98	190	26	haemorrhagic	haemorrhagic	JJ
cord-016903-z2vqfq98	190	27	manifestations	manifestation	NNS
cord-016903-z2vqfq98	190	28	.	.	.
cord-016903-z2vqfq98	191	1	Halfofthese	halfofthese	JJ
cord-016903-z2vqfq98	191	2	persons	person	NNS
cord-016903-z2vqfq98	191	3	die	die	VBP
cord-016903-z2vqfq98	191	4	10	10	CD
cord-016903-z2vqfq98	191	5	-	-	SYM
cord-016903-z2vqfq98	191	6	14days	14days	CD
cord-016903-z2vqfq98	191	7	after	after	IN
cord-016903-z2vqfq98	191	8	the	the	DT
cord-016903-z2vqfq98	191	9	onset	onset	NN
cord-016903-z2vqfq98	191	10	ofillness	ofillness	NN
cord-016903-z2vqfq98	191	11	.	.	.
cord-016903-z2vqfq98	192	1	The	the	DT
cord-016903-z2vqfq98	192	2	WHO	who	WP
cord-016903-z2vqfq98	192	3	estimates	estimate	VBZ
cord-016903-z2vqfq98	192	4	that	that	IN
cord-016903-z2vqfq98	192	5	a	a	DT
cord-016903-z2vqfq98	192	6	total	total	JJ
cord-016903-z2vqfq98	192	7	of200,000	of200,000	CD
cord-016903-z2vqfq98	192	8	cases	case	NNS
cord-016903-z2vqfq98	192	9	ofYF	ofyf	NN
cord-016903-z2vqfq98	192	10	occur	occur	VBP
cord-016903-z2vqfq98	192	11	each	each	DT
cord-016903-z2vqfq98	192	12	year	year	NN
cord-016903-z2vqfq98	192	13	,	,	,
cord-016903-z2vqfq98	192	14	with	with	IN
cord-016903-z2vqfq98	192	15	about	about	RB
cord-016903-z2vqfq98	192	16	30,000	30,000	CD
cord-016903-z2vqfq98	192	17	deaths	death	NNS
cord-016903-z2vqfq98	192	18	.	.	.
cord-016903-z2vqfq98	193	1	6oYF	6oYF	NNP
cord-016903-z2vqfq98	193	2	also	also	RB
cord-016903-z2vqfq98	193	3	represents	represent	VBZ
cord-016903-z2vqfq98	193	4	a	a	DT
cord-016903-z2vqfq98	193	5	significant	significant	JJ
cord-016903-z2vqfq98	193	6	risk	risk	NN
cord-016903-z2vqfq98	193	7	to	to	IN
cord-016903-z2vqfq98	193	8	more	more	JJR
cord-016903-z2vqfq98	193	9	than	than	IN
cord-016903-z2vqfq98	193	10	3	3	CD
cord-016903-z2vqfq98	193	11	million	million	CD
cord-016903-z2vqfq98	193	12	travelers	traveler	NNS
cord-016903-z2vqfq98	193	13	that	that	WDT
cord-016903-z2vqfq98	193	14	visit	visit	VBP
cord-016903-z2vqfq98	193	15	YF	YF	NNP
cord-016903-z2vqfq98	193	16	-	-	HYPH
cord-016903-z2vqfq98	193	17	endemic	endemic	JJ
cord-016903-z2vqfq98	193	18	areas	area	NNS
cord-016903-z2vqfq98	193	19	each	each	DT
cord-016903-z2vqfq98	193	20	year	year	NN
cord-016903-z2vqfq98	193	21	.	.	.
cord-016903-z2vqfq98	194	1	Neonates	neonate	NNS
cord-016903-z2vqfq98	194	2	and	and	CC
cord-016903-z2vqfq98	194	3	elderly	elderly	JJ
cord-016903-z2vqfq98	194	4	individuals	individual	NNS
cord-016903-z2vqfq98	194	5	demonstrate	demonstrate	VBP
cord-016903-z2vqfq98	194	6	the	the	DT
cord-016903-z2vqfq98	194	7	highest	high	JJS
cord-016903-z2vqfq98	194	8	mortality	mortality	NN
cord-016903-z2vqfq98	194	9	when	when	WRB
cord-016903-z2vqfq98	194	10	infected	infect	VBN
cord-016903-z2vqfq98	194	11	by	by	IN
cord-016903-z2vqfq98	194	12	the	the	DT
cord-016903-z2vqfq98	194	13	YF	YF	NNP
cord-016903-z2vqfq98	194	14	virus	virus	NN
cord-016903-z2vqfq98	194	15	.	.	.
cord-016903-z2vqfq98	195	1	As	as	IN
cord-016903-z2vqfq98	195	2	there	there	EX
cord-016903-z2vqfq98	195	3	is	be	VBZ
cord-016903-z2vqfq98	195	4	no	no	DT
cord-016903-z2vqfq98	195	5	specific	specific	JJ
cord-016903-z2vqfq98	195	6	antiviral	antiviral	JJ
cord-016903-z2vqfq98	195	7	treatment	treatment	NN
cord-016903-z2vqfq98	195	8	against	against	IN
cord-016903-z2vqfq98	195	9	YF	YF	NNP
cord-016903-z2vqfq98	195	10	available	available	JJ
cord-016903-z2vqfq98	195	11	yet	yet	RB
cord-016903-z2vqfq98	195	12	,	,	,
cord-016903-z2vqfq98	195	13	vaccination	vaccination	NN
cord-016903-z2vqfq98	195	14	is	be	VBZ
cord-016903-z2vqfq98	195	15	the	the	DT
cord-016903-z2vqfq98	195	16	only	only	JJ
cord-016903-z2vqfq98	195	17	way	way	NN
cord-016903-z2vqfq98	195	18	to	to	TO
cord-016903-z2vqfq98	195	19	protect	protect	VB
cord-016903-z2vqfq98	195	20	persons	person	NNS
cord-016903-z2vqfq98	195	21	from	from	IN
cord-016903-z2vqfq98	195	22	YF	YF	NNP
cord-016903-z2vqfq98	195	23	disease	disease	NN
cord-016903-z2vqfq98	195	24	.	.	.
cord-016903-z2vqfq98	196	1	The	the	DT
cord-016903-z2vqfq98	196	2	currently	currently	RB
cord-016903-z2vqfq98	196	3	available	available	JJ
cord-016903-z2vqfq98	196	4	vaccine	vaccine	NN
cord-016903-z2vqfq98	196	5	contains	contain	VBZ
cord-016903-z2vqfq98	196	6	a	a	DT
cord-016903-z2vqfq98	196	7	live	live	RB
cord-016903-z2vqfq98	196	8	-	-	HYPH
cord-016903-z2vqfq98	196	9	attenuated	attenuate	VBN
cord-016903-z2vqfq98	196	10	17D	17d	CD
cord-016903-z2vqfq98	196	11	strain	strain	NN
cord-016903-z2vqfq98	196	12	virus	virus	NN
cord-016903-z2vqfq98	196	13	(	(	-LRB-
cord-016903-z2vqfq98	196	14	Table	table	NN
cord-016903-z2vqfq98	196	15	2	2	CD
cord-016903-z2vqfq98	196	16	)	)	-RRB-
cord-016903-z2vqfq98	196	17	and	and	CC
cord-016903-z2vqfq98	196	18	has	have	VBZ
cord-016903-z2vqfq98	196	19	been	be	VBN
cord-016903-z2vqfq98	196	20	shown	show	VBN
cord-016903-z2vqfq98	196	21	to	to	TO
cord-016903-z2vqfq98	196	22	be	be	VB
cord-016903-z2vqfq98	196	23	safe	safe	JJ
cord-016903-z2vqfq98	196	24	and	and	CC
cord-016903-z2vqfq98	196	25	highly	highly	RB
cord-016903-z2vqfq98	196	26	potent	potent	JJ
cord-016903-z2vqfq98	196	27	.	.	.
cord-016903-z2vqfq98	196	28	"	"	''
cord-016903-z2vqfq98	197	1	However	however	RB
cord-016903-z2vqfq98	197	2	,	,	,
cord-016903-z2vqfq98	197	3	due	due	IN
cord-016903-z2vqfq98	197	4	to	to	IN
cord-016903-z2vqfq98	197	5	the	the	DT
cord-016903-z2vqfq98	197	6	increased	increase	VBN
cord-016903-z2vqfq98	197	7	use	use	NN
cord-016903-z2vqfq98	197	8	in	in	IN
cord-016903-z2vqfq98	197	9	international	international	JJ
cord-016903-z2vqfq98	197	10	travelers	traveler	NNS
cord-016903-z2vqfq98	197	11	,	,	,
cord-016903-z2vqfq98	197	12	it	-PRON-	PRP
cord-016903-z2vqfq98	197	13	has	have	VBZ
cord-016903-z2vqfq98	197	14	become	become	VBN
cord-016903-z2vqfq98	197	15	evident	evident	JJ
cord-016903-z2vqfq98	197	16	that	that	IN
cord-016903-z2vqfq98	197	17	advanced	advanced	JJ
cord-016903-z2vqfq98	197	18	age	age	NN
cord-016903-z2vqfq98	197	19	might	may	MD
cord-016903-z2vqfq98	197	20	be	be	VB
cord-016903-z2vqfq98	197	21	a	a	DT
cord-016903-z2vqfq98	197	22	risk	risk	NN
cord-016903-z2vqfq98	197	23	factor	factor	NN
cord-016903-z2vqfq98	197	24	for	for	IN
cord-016903-z2vqfq98	197	25	serious	serious	JJ
cord-016903-z2vqfq98	197	26	adverse	adverse	JJ
cord-016903-z2vqfq98	197	27	effects	effect	NNS
cord-016903-z2vqfq98	197	28	and	and	CC
cord-016903-z2vqfq98	197	29	even	even	RB
cord-016903-z2vqfq98	197	30	deam	deam	NNP
cord-016903-z2vqfq98	197	31	.	.	.
cord-016903-z2vqfq98	197	32	62	62	CD
cord-016903-z2vqfq98	198	1	Compared	compare	VBN
cord-016903-z2vqfq98	198	2	with	with	IN
cord-016903-z2vqfq98	198	3	persons	person	NNS
cord-016903-z2vqfq98	198	4	aged	age	VBN
cord-016903-z2vqfq98	198	5	25	25	CD
cord-016903-z2vqfq98	198	6	-	-	SYM
cord-016903-z2vqfq98	198	7	44	44	CD
cord-016903-z2vqfq98	198	8	years	year	NNS
cord-016903-z2vqfq98	198	9	,	,	,
cord-016903-z2vqfq98	198	10	individuals	individual	NNS
cord-016903-z2vqfq98	198	11	aged	age	VBN
cord-016903-z2vqfq98	198	12	<	<	XX
cord-016903-z2vqfq98	198	13	75	75	CD
cord-016903-z2vqfq98	198	14	had	have	VBD
cord-016903-z2vqfq98	198	15	an	an	DT
cord-016903-z2vqfq98	198	16	18-fold	18-fold	RB
cord-016903-z2vqfq98	198	17	greater	great	JJR
cord-016903-z2vqfq98	198	18	risk	risk	NN
cord-016903-z2vqfq98	198	19	to	to	TO
cord-016903-z2vqfq98	198	20	experience	experience	VB
cord-016903-z2vqfq98	198	21	serious	serious	JJ
cord-016903-z2vqfq98	198	22	adverse	adverse	JJ
cord-016903-z2vqfq98	198	23	events	event	NNS
cord-016903-z2vqfq98	198	24	after	after	IN
cord-016903-z2vqfq98	198	25	vaccination	vaccination	NN
cord-016903-z2vqfq98	198	26	.	.	.
cord-016903-z2vqfq98	199	1	The	the	DT
cord-016903-z2vqfq98	199	2	rate	rate	NN
cord-016903-z2vqfq98	199	3	for	for	IN
cord-016903-z2vqfq98	199	4	systemic	systemic	JJ
cord-016903-z2vqfq98	199	5	illness	illness	NN
cord-016903-z2vqfq98	199	6	requiring	require	VBG
cord-016903-z2vqfq98	199	7	hospitalization	hospitalization	NN
cord-016903-z2vqfq98	199	8	or	or	CC
cord-016903-z2vqfq98	199	9	leading	lead	VBG
cord-016903-z2vqfq98	199	10	to	to	IN
cord-016903-z2vqfq98	199	11	death	death	NN
cord-016903-z2vqfq98	199	12	after	after	IN
cord-016903-z2vqfq98	199	13	YF	YF	NNP
cord-016903-z2vqfq98	199	14	vaccination	vaccination	NN
cord-016903-z2vqfq98	199	15	was	be	VBD
cord-016903-z2vqfq98	199	16	reported	report	VBN
cord-016903-z2vqfq98	199	17	to	to	TO
cord-016903-z2vqfq98	199	18	be	be	VB
cord-016903-z2vqfq98	199	19	3.5	3.5	CD
cord-016903-z2vqfq98	199	20	per	per	IN
cord-016903-z2vqfq98	199	21	100,000	100,000	CD
cord-016903-z2vqfq98	199	22	among	among	IN
cord-016903-z2vqfq98	199	23	people	people	NNS
cord-016903-z2vqfq98	199	24	65	65	CD
cord-016903-z2vqfq98	199	25	to	to	TO
cord-016903-z2vqfq98	199	26	75	75	CD
cord-016903-z2vqfq98	199	27	years	year	NNS
cord-016903-z2vqfq98	199	28	of	of	IN
cord-016903-z2vqfq98	199	29	age	age	NN
cord-016903-z2vqfq98	199	30	and	and	CC
cord-016903-z2vqfq98	199	31	9.1	9.1	CD
cord-016903-z2vqfq98	199	32	per	per	IN
cord-016903-z2vqfq98	199	33	100,000	100,000	CD
cord-016903-z2vqfq98	199	34	for	for	IN
cord-016903-z2vqfq98	199	35	people	people	NNS
cord-016903-z2vqfq98	199	36	more	more	JJR
cord-016903-z2vqfq98	199	37	than	than	IN
cord-016903-z2vqfq98	199	38	75	75	CD
cord-016903-z2vqfq98	199	39	years	year	NNS
cord-016903-z2vqfq98	199	40	.	.	.
cord-016903-z2vqfq98	200	1	Furthermore	furthermore	RB
cord-016903-z2vqfq98	200	2	,	,	,
cord-016903-z2vqfq98	200	3	there	there	EX
cord-016903-z2vqfq98	200	4	are	be	VBP
cord-016903-z2vqfq98	200	5	no	no	DT
cord-016903-z2vqfq98	200	6	studies	study	NNS
cord-016903-z2vqfq98	200	7	available	available	JJ
cord-016903-z2vqfq98	200	8	that	that	WDT
cord-016903-z2vqfq98	200	9	demonstrated	demonstrate	VBD
cord-016903-z2vqfq98	200	10	the	the	DT
cord-016903-z2vqfq98	200	11	efficacy	efficacy	NN
cord-016903-z2vqfq98	200	12	of	of	IN
cord-016903-z2vqfq98	200	13	the	the	DT
cord-016903-z2vqfq98	200	14	YF	YF	NNP
cord-016903-z2vqfq98	200	15	vaccine	vaccine	NN
cord-016903-z2vqfq98	200	16	in	in	IN
cord-016903-z2vqfq98	200	17	elderly	elderly	JJ
cord-016903-z2vqfq98	200	18	persons	person	NNS
cord-016903-z2vqfq98	200	19	.	.	.
cord-016903-z2vqfq98	201	1	Accordingly	accordingly	RB
cord-016903-z2vqfq98	201	2	,	,	,
cord-016903-z2vqfq98	201	3	recommendations	recommendation	NNS
cord-016903-z2vqfq98	201	4	and	and	CC
cord-016903-z2vqfq98	201	5	manufacturing	manufacturing	NN
cord-016903-z2vqfq98	201	6	standards	standard	NNS
cord-016903-z2vqfq98	201	7	have	have	VBP
cord-016903-z2vqfq98	201	8	been	be	VBN
cord-016903-z2vqfq98	201	9	modified	modify	VBN
cord-016903-z2vqfq98	201	10	to	to	TO
cord-016903-z2vqfq98	201	11	increase	increase	VB
cord-016903-z2vqfq98	201	12	vaccine	vaccine	NN
cord-016903-z2vqfq98	201	13	safety	safety	NN
cord-016903-z2vqfq98	201	14	in	in	IN
cord-016903-z2vqfq98	201	15	elderly	elderly	JJ
cord-016903-z2vqfq98	201	16	persons	person	NNS
cord-016903-z2vqfq98	201	17	.	.	.
cord-016903-z2vqfq98	202	1	Although	although	IN
cord-016903-z2vqfq98	202	2	the	the	DT
cord-016903-z2vqfq98	202	3	benefit	benefit	NN
cord-016903-z2vqfq98	202	4	-	-	HYPH
cord-016903-z2vqfq98	202	5	risk	risk	NN
cord-016903-z2vqfq98	202	6	ratio	ratio	NN
cord-016903-z2vqfq98	202	7	still	still	RB
cord-016903-z2vqfq98	202	8	favors	favor	VBZ
cord-016903-z2vqfq98	202	9	the	the	DT
cord-016903-z2vqfq98	202	10	vaccination	vaccination	NN
cord-016903-z2vqfq98	202	11	ofpeople	ofpeople	NN
cord-016903-z2vqfq98	202	12	at	at	IN
cord-016903-z2vqfq98	202	13	high	high	JJ
cord-016903-z2vqfq98	202	14	risk	risk	NN
cord-016903-z2vqfq98	202	15	for	for	IN
cord-016903-z2vqfq98	202	16	infection	infection	NN
cord-016903-z2vqfq98	202	17	and	and	CC
cord-016903-z2vqfq98	202	18	outlines	outline	VBZ
cord-016903-z2vqfq98	202	19	the	the	DT
cord-016903-z2vqfq98	202	20	vaccine	vaccine	NN
cord-016903-z2vqfq98	202	21	's	's	POS
cord-016903-z2vqfq98	202	22	fundamental	fundamental	JJ
cord-016903-z2vqfq98	202	23	role	role	NN
cord-016903-z2vqfq98	202	24	in	in	IN
cord-016903-z2vqfq98	202	25	disease	disease	NN
cord-016903-z2vqfq98	202	26	prevention	prevention	NN
cord-016903-z2vqfq98	202	27	and	and	CC
cord-016903-z2vqfq98	202	28	control	control	NN
cord-016903-z2vqfq98	202	29	,	,	,
cord-016903-z2vqfq98	202	30	efforts	effort	NNS
cord-016903-z2vqfq98	202	31	to	to	TO
cord-016903-z2vqfq98	202	32	improve	improve	VB
cord-016903-z2vqfq98	202	33	safety	safety	NN
cord-016903-z2vqfq98	202	34	and	and	CC
cord-016903-z2vqfq98	202	35	to	to	TO
cord-016903-z2vqfq98	202	36	ensure	ensure	VB
cord-016903-z2vqfq98	202	37	vaccine	vaccine	NN
cord-016903-z2vqfq98	202	38	efficacy	efficacy	NN
cord-016903-z2vqfq98	202	39	in	in	IN
cord-016903-z2vqfq98	202	40	elderly	elderly	JJ
cord-016903-z2vqfq98	202	41	persons	person	NNS
cord-016903-z2vqfq98	202	42	are	be	VBP
cord-016903-z2vqfq98	202	43	ofurgent	ofurgent	JJ
cord-016903-z2vqfq98	202	44	need	need	NN
cord-016903-z2vqfq98	202	45	.	.	.
cord-016903-z2vqfq98	203	1	The	the	DT
cord-016903-z2vqfq98	203	2	term	term	NN
cord-016903-z2vqfq98	203	3	immunosenescence	immunosenescence	RB
cord-016903-z2vqfq98	203	4	refers	refer	VBZ
cord-016903-z2vqfq98	203	5	to	to	IN
cord-016903-z2vqfq98	203	6	a	a	DT
cord-016903-z2vqfq98	203	7	complex	complex	JJ
cord-016903-z2vqfq98	203	8	remodeling	remodeling	NN
cord-016903-z2vqfq98	203	9	ofthe	ofthe	DT
cord-016903-z2vqfq98	203	10	immune	immune	JJ
cord-016903-z2vqfq98	203	11	system	system	NN
cord-016903-z2vqfq98	203	12	in	in	IN
cord-016903-z2vqfq98	203	13	old	old	JJ
cord-016903-z2vqfq98	203	14	age	age	NN
cord-016903-z2vqfq98	203	15	and	and	CC
cord-016903-z2vqfq98	203	16	may	may	MD
cord-016903-z2vqfq98	203	17	contribute	contribute	VB
cord-016903-z2vqfq98	203	18	significantly	significantly	RB
cord-016903-z2vqfq98	203	19	to	to	IN
cord-016903-z2vqfq98	203	20	morbidity	morbidity	NN
cord-016903-z2vqfq98	203	21	and	and	CC
cord-016903-z2vqfq98	203	22	mortality	mortality	NN
cord-016903-z2vqfq98	203	23	in	in	IN
cord-016903-z2vqfq98	203	24	the	the	DT
cord-016903-z2vqfq98	203	25	elderly	elderly	JJ
cord-016903-z2vqfq98	203	26	.	.	.
cord-016903-z2vqfq98	204	1	Thymic	thymic	JJ
cord-016903-z2vqfq98	204	2	involution	involution	NN
cord-016903-z2vqfq98	204	3	,	,	,
cord-016903-z2vqfq98	204	4	telomere	telomere	NN
cord-016903-z2vqfq98	204	5	shortening	shortening	NN
cord-016903-z2vqfq98	204	6	,	,	,
cord-016903-z2vqfq98	204	7	T	t	NN
cord-016903-z2vqfq98	204	8	-	-	HYPH
cord-016903-z2vqfq98	204	9	cell	cell	NN
cord-016903-z2vqfq98	204	10	signal	signal	NN
cord-016903-z2vqfq98	204	11	transduction	transduction	NN
cord-016903-z2vqfq98	204	12	changes	change	NNS
cord-016903-z2vqfq98	204	13	,	,	,
cord-016903-z2vqfq98	204	14	alterations	alteration	NNS
cord-016903-z2vqfq98	204	15	in	in	IN
cord-016903-z2vqfq98	204	16	the	the	DT
cord-016903-z2vqfq98	204	17	interaction	interaction	NN
cord-016903-z2vqfq98	204	18	of	of	IN
cord-016903-z2vqfq98	204	19	the	the	DT
cord-016903-z2vqfq98	204	20	innate	innate	JJ
cord-016903-z2vqfq98	204	21	and	and	CC
cord-016903-z2vqfq98	204	22	adaptive	adaptive	JJ
cord-016903-z2vqfq98	204	23	immune	immune	JJ
cord-016903-z2vqfq98	204	24	response	response	NN
cord-016903-z2vqfq98	204	25	,	,	,
cord-016903-z2vqfq98	204	26	impaired	impair	VBN
cord-016903-z2vqfq98	204	27	DNA	dna	NN
cord-016903-z2vqfq98	204	28	repair	repair	NN
cord-016903-z2vqfq98	204	29	and	and	CC
cord-016903-z2vqfq98	204	30	antioxidant	antioxidant	NN
cord-016903-z2vqfq98	204	31	mechanisms	mechanism	NNS
cord-016903-z2vqfq98	204	32	as	as	RB
cord-016903-z2vqfq98	204	33	well	well	RB
cord-016903-z2vqfq98	204	34	as	as	IN
cord-016903-z2vqfq98	204	35	persistent	persistent	JJ
cord-016903-z2vqfq98	204	36	antigenic	antigenic	JJ
cord-016903-z2vqfq98	204	37	stress	stress	NN
cord-016903-z2vqfq98	204	38	may	may	MD
cord-016903-z2vqfq98	204	39	all	all	DT
cord-016903-z2vqfq98	204	40	be	be	VB
cord-016903-z2vqfq98	204	41	factors	factor	NNS
cord-016903-z2vqfq98	204	42	contributing	contribute	VBG
cord-016903-z2vqfq98	204	43	to	to	IN
cord-016903-z2vqfq98	204	44	immunosenescence	immunosenescence	NNP
cord-016903-z2vqfq98	204	45	.	.	.
cord-016903-z2vqfq98	205	1	Although	although	IN
cord-016903-z2vqfq98	205	2	perturbations	perturbation	NNS
cord-016903-z2vqfq98	205	3	ofinnate	ofinnate	NN
cord-016903-z2vqfq98	205	4	immune	immune	JJ
cord-016903-z2vqfq98	205	5	system	system	NN
cord-016903-z2vqfq98	205	6	components	component	NNS
cord-016903-z2vqfq98	205	7	have	have	VBP
cord-016903-z2vqfq98	205	8	been	be	VBN
cord-016903-z2vqfq98	205	9	described	describe	VBN
cord-016903-z2vqfq98	205	10	,	,	,
cord-016903-z2vqfq98	205	11	much	much	JJ
cord-016903-z2vqfq98	205	12	ofthe	ofthe	DT
cord-016903-z2vqfq98	205	13	decrease	decrease	NN
cord-016903-z2vqfq98	205	14	in	in	IN
cord-016903-z2vqfq98	205	15	immunoresponsiveness	immunoresponsiveness	NN
cord-016903-z2vqfq98	205	16	seen	see	VBN
cord-016903-z2vqfq98	205	17	in	in	IN
cord-016903-z2vqfq98	205	18	elderly	elderly	JJ
cord-016903-z2vqfq98	205	19	people	people	NNS
cord-016903-z2vqfq98	205	20	is	be	VBZ
cord-016903-z2vqfq98	205	21	associated	associate	VBN
cord-016903-z2vqfq98	205	22	with	with	IN
cord-016903-z2vqfq98	205	23	changes	change	NNS
cord-016903-z2vqfq98	205	24	in	in	IN
cord-016903-z2vqfq98	205	25	T	t	NN
cord-016903-z2vqfq98	205	26	-	-	HYPH
cord-016903-z2vqfq98	205	27	cell	cell	NN
cord-016903-z2vqfq98	205	28	responses	response	NNS
cord-016903-z2vqfq98	205	29	.	.	.
cord-016903-z2vqfq98	206	1	This	this	DT
cord-016903-z2vqfq98	206	2	is	be	VBZ
cord-016903-z2vqfq98	206	3	due	due	JJ
cord-016903-z2vqfq98	206	4	to	to	IN
cord-016903-z2vqfq98	206	5	the	the	DT
cord-016903-z2vqfq98	206	6	continuous	continuous	JJ
cord-016903-z2vqfq98	206	7	loss	loss	NN
cord-016903-z2vqfq98	206	8	offunctional	offunctional	JJ
cord-016903-z2vqfq98	206	9	thymic	thymic	JJ
cord-016903-z2vqfq98	206	10	tissue	tissue	NN
cord-016903-z2vqfq98	206	11	with	with	IN
cord-016903-z2vqfq98	206	12	increasing	increase	VBG
cord-016903-z2vqfq98	206	13	age	age	NN
cord-016903-z2vqfq98	206	14	.	.	.
cord-016903-z2vqfq98	207	1	63.64The	63.64the	JJ
cord-016903-z2vqfq98	207	2	thymus	thymus	NN
cord-016903-z2vqfq98	207	3	,	,	,
cord-016903-z2vqfq98	207	4	the	the	DT
cord-016903-z2vqfq98	207	5	central	central	JJ
cord-016903-z2vqfq98	207	6	lymphoid	lymphoid	JJ
cord-016903-z2vqfq98	207	7	organ	organ	NN
cord-016903-z2vqfq98	207	8	,	,	,
cord-016903-z2vqfq98	207	9	is	be	VBZ
cord-016903-z2vqfq98	207	10	responsible	responsible	JJ
cord-016903-z2vqfq98	207	11	for	for	IN
cord-016903-z2vqfq98	207	12	the	the	DT
cord-016903-z2vqfq98	207	13	maturation	maturation	NN
cord-016903-z2vqfq98	207	14	and	and	CC
cord-016903-z2vqfq98	207	15	selection	selection	NN
cord-016903-z2vqfq98	207	16	ofso	ofso	RB
cord-016903-z2vqfq98	207	17	-	-	HYPH
cord-016903-z2vqfq98	207	18	called	call	VBN
cord-016903-z2vqfq98	207	19	naive	naive	JJ
cord-016903-z2vqfq98	207	20	T	t	NN
cord-016903-z2vqfq98	207	21	-	-	HYPH
cord-016903-z2vqfq98	207	22	cells	cell	NNS
cord-016903-z2vqfq98	207	23	that	that	WDT
cord-016903-z2vqfq98	207	24	regenerate	regenerate	VBP
cord-016903-z2vqfq98	207	25	the	the	DT
cord-016903-z2vqfq98	207	26	peripheral	peripheral	JJ
cord-016903-z2vqfq98	207	27	Tcell	Tcell	NNP
cord-016903-z2vqfq98	207	28	pool	pool	NN
cord-016903-z2vqfq98	207	29	and	and	CC
cord-016903-z2vqfq98	207	30	retain	retain	VB
cord-016903-z2vqfq98	207	31	the	the	DT
cord-016903-z2vqfq98	207	32	capability	capability	NN
cord-016903-z2vqfq98	207	33	ofthe	ofthe	DT
cord-016903-z2vqfq98	207	34	immune	immune	JJ
cord-016903-z2vqfq98	207	35	system	system	NN
cord-016903-z2vqfq98	207	36	to	to	TO
cord-016903-z2vqfq98	207	37	respond	respond	VB
cord-016903-z2vqfq98	207	38	to	to	IN
cord-016903-z2vqfq98	207	39	a	a	DT
cord-016903-z2vqfq98	207	40	variety	variety	NN
cord-016903-z2vqfq98	207	41	ofdifferent	ofdifferent	JJ
cord-016903-z2vqfq98	207	42	pathogens	pathogen	NNS
cord-016903-z2vqfq98	207	43	.	.	.
cord-016903-z2vqfq98	208	1	In	in	IN
cord-016903-z2vqfq98	208	2	old	old	JJ
cord-016903-z2vqfq98	208	3	age	age	NN
cord-016903-z2vqfq98	208	4	,	,	,
cord-016903-z2vqfq98	208	5	the	the	DT
cord-016903-z2vqfq98	208	6	number	number	NN
cord-016903-z2vqfq98	208	7	ofnaive	ofnaive	NNP
cord-016903-z2vqfq98	208	8	T	T	NNP
cord-016903-z2vqfq98	208	9	-	-	HYPH
cord-016903-z2vqfq98	208	10	celIs	celIs	NNP
cord-016903-z2vqfq98	208	11	decreases	decrease	NNS
cord-016903-z2vqfq98	208	12	while	while	IN
cord-016903-z2vqfq98	208	13	the	the	DT
cord-016903-z2vqfq98	208	14	number	number	NN
cord-016903-z2vqfq98	208	15	ofantigen	ofantigen	NN
cord-016903-z2vqfq98	208	16	-	-	HYPH
cord-016903-z2vqfq98	208	17	experienced	experience	VBN
cord-016903-z2vqfq98	208	18	'	'	''
cord-016903-z2vqfq98	208	19	Tcells	Tcells	NNP
cord-016903-z2vqfq98	208	20	increases	increase	VBZ
cord-016903-z2vqfq98	208	21	.	.	.
cord-016903-z2vqfq98	209	1	65	65	CD
cord-016903-z2vqfq98	209	2	.66	.66	.
cord-016903-z2vqfq98	210	1	These	these	DT
cord-016903-z2vqfq98	210	2	antigen	antigen	NN
cord-016903-z2vqfq98	210	3	-	-	HYPH
cord-016903-z2vqfq98	210	4	experienced	experience	VBN
cord-016903-z2vqfq98	210	5	T	T	NNP
cord-016903-z2vqfq98	210	6	-	-	HYPH
cord-016903-z2vqfq98	210	7	celIs	celIs	NNP
cord-016903-z2vqfq98	210	8	include	include	VBP
cord-016903-z2vqfq98	210	9	a	a	DT
cord-016903-z2vqfq98	210	10	substantial	substantial	JJ
cord-016903-z2vqfq98	210	11	proportion	proportion	NN
cord-016903-z2vqfq98	210	12	of	of	IN
cord-016903-z2vqfq98	210	13	senescent	senescent	JJ
cord-016903-z2vqfq98	210	14	memory	memory	NN
cord-016903-z2vqfq98	210	15	-	-	HYPH
cord-016903-z2vqfq98	210	16	effector	effector	NN
cord-016903-z2vqfq98	210	17	T	T	NNP
cord-016903-z2vqfq98	210	18	-	-	HYPH
cord-016903-z2vqfq98	210	19	cells	cell	NNS
cord-016903-z2vqfq98	210	20	that	that	WDT
cord-016903-z2vqfq98	210	21	accumulate	accumulate	VBP
cord-016903-z2vqfq98	210	22	in	in	IN
cord-016903-z2vqfq98	210	23	elderly	elderly	JJ
cord-016903-z2vqfq98	210	24	persons	person	NNS
cord-016903-z2vqfq98	210	25	.	.	.
cord-016903-z2vqfq98	211	1	Senescent	senescent	JJ
cord-016903-z2vqfq98	211	2	memory	memory	NN
cord-016903-z2vqfq98	211	3	-	-	HYPH
cord-016903-z2vqfq98	211	4	effector	effector	NN
cord-016903-z2vqfq98	211	5	TcelIs	tcelis	ADD
cord-016903-z2vqfq98	211	6	display	display	NN
cord-016903-z2vqfq98	211	7	phenotypic	phenotypic	NNS
cord-016903-z2vqfq98	211	8	(	(	-LRB-
cord-016903-z2vqfq98	211	9	loss	loss	NN
cord-016903-z2vqfq98	211	10	ofcostimulatory	ofcostimulatory	NN
cord-016903-z2vqfq98	211	11	molecules	molecule	NNS
cord-016903-z2vqfq98	211	12	such	such	JJ
cord-016903-z2vqfq98	211	13	as	as	IN
cord-016903-z2vqfq98	211	14	CD28	CD28	NNP
cord-016903-z2vqfq98	211	15	and	and	CC
cord-016903-z2vqfq98	211	16	CD40L	cd40l	NN
cord-016903-z2vqfq98	211	17	)	)	-RRB-
cord-016903-z2vqfq98	211	18	as	as	RB
cord-016903-z2vqfq98	211	19	well	well	RB
cord-016903-z2vqfq98	211	20	as	as	IN
cord-016903-z2vqfq98	211	21	functional	functional	JJ
cord-016903-z2vqfq98	211	22	changes	change	NNS
cord-016903-z2vqfq98	211	23	(	(	-LRB-
cord-016903-z2vqfq98	211	24	altered	alter	VBN
cord-016903-z2vqfq98	211	25	cytokine	cytokine	NN
cord-016903-z2vqfq98	211	26	production	production	NN
cord-016903-z2vqfq98	211	27	profile	profile	NN
cord-016903-z2vqfq98	211	28	,	,	,
cord-016903-z2vqfq98	211	29	decreased	decrease	VBD
cord-016903-z2vqfq98	211	30	proliferative	proliferative	JJ
cord-016903-z2vqfq98	211	31	response	response	NN
cord-016903-z2vqfq98	211	32	,	,	,
cord-016903-z2vqfq98	211	33	shortened	shorten	VBN
cord-016903-z2vqfq98	211	34	telomeres	telomere	NNS
cord-016903-z2vqfq98	211	35	,	,	,
cord-016903-z2vqfq98	211	36	increased	increase	VBN
cord-016903-z2vqfq98	211	37	resistance	resistance	NN
cord-016903-z2vqfq98	211	38	to	to	IN
cord-016903-z2vqfq98	211	39	programmed	program	VBN
cord-016903-z2vqfq98	211	40	cell	cell	NN
cord-016903-z2vqfq98	211	41	-	-	HYPH
cord-016903-z2vqfq98	211	42	death	death	NN
cord-016903-z2vqfq98	211	43	and	and	CC
cord-016903-z2vqfq98	211	44	restricted	restrict	VBN
cord-016903-z2vqfq98	211	45	T	t	NN
cord-016903-z2vqfq98	211	46	-	-	HYPH
cord-016903-z2vqfq98	211	47	cell	cell	NN
cord-016903-z2vqfq98	211	48	diversity).67.68Ofparticular	diversity).67.68ofparticular	NN
cord-016903-z2vqfq98	211	49	importance	importance	NN
cord-016903-z2vqfq98	211	50	,	,	,
cord-016903-z2vqfq98	211	51	the	the	DT
cord-016903-z2vqfq98	211	52	senescent	senescent	JJ
cord-016903-z2vqfq98	211	53	CD8+CD28-memory	cd8+cd28-memory	JJ
cord-016903-z2vqfq98	211	54	-	-	HYPH
cord-016903-z2vqfq98	211	55	effector	effector	JJ
cord-016903-z2vqfq98	211	56	T	t	NN
cord-016903-z2vqfq98	211	57	-	-	HYPH
cord-016903-z2vqfq98	211	58	cell	cell	NN
cord-016903-z2vqfq98	211	59	population	population	NN
cord-016903-z2vqfq98	211	60	predominantly	predominantly	RB
cord-016903-z2vqfq98	211	61	produces	produce	VBZ
cord-016903-z2vqfq98	211	62	the	the	DT
cord-016903-z2vqfq98	211	63	pro	pro	JJ
cord-016903-z2vqfq98	211	64	-	-	JJ
cord-016903-z2vqfq98	211	65	inflammatory	inflammatory	JJ
cord-016903-z2vqfq98	211	66	cytokine	cytokine	NN
cord-016903-z2vqfq98	211	67	gamma	gamma	NN
cord-016903-z2vqfq98	211	68	interferon	interferon	NN
cord-016903-z2vqfq98	211	69	(	(	-LRB-
cord-016903-z2vqfq98	211	70	IFNy	IFNy	NNP
cord-016903-z2vqfq98	211	71	)	)	-RRB-
cord-016903-z2vqfq98	211	72	,	,	,
cord-016903-z2vqfq98	211	73	but	but	CC
cord-016903-z2vqfq98	211	74	does	do	VBZ
cord-016903-z2vqfq98	211	75	not	not	RB
cord-016903-z2vqfq98	211	76	produce	produce	VB
cord-016903-z2vqfq98	211	77	interleukin	interleukin	NN
cord-016903-z2vqfq98	211	78	2	2	CD
cord-016903-z2vqfq98	211	79	(	(	-LRB-
cord-016903-z2vqfq98	211	80	IL-2	IL-2	NNP
cord-016903-z2vqfq98	211	81	)	)	-RRB-
cord-016903-z2vqfq98	211	82	and	and	CC
cord-016903-z2vqfq98	211	83	the	the	DT
cord-016903-z2vqfq98	211	84	anti	anti	JJ
cord-016903-z2vqfq98	211	85	-	-	JJ
cord-016903-z2vqfq98	211	86	inflammatory	inflammatory	JJ
cord-016903-z2vqfq98	211	87	,	,	,
cord-016903-z2vqfq98	211	88	B	b	NN
cord-016903-z2vqfq98	211	89	-	-	HYPH
cord-016903-z2vqfq98	211	90	cell	cell	NN
cord-016903-z2vqfq98	211	91	stimulating	stimulate	VBG
cord-016903-z2vqfq98	211	92	cytokine	cytokine	NN
cord-016903-z2vqfq98	211	93	IL-4	IL-4	NNP
cord-016903-z2vqfq98	211	94	.	.	.
cord-016903-z2vqfq98	212	1	43	43	CD
cord-016903-z2vqfq98	213	1	Recent	recent	JJ
cord-016903-z2vqfq98	213	2	data	datum	NNS
cord-016903-z2vqfq98	213	3	also	also	RB
cord-016903-z2vqfq98	213	4	support	support	VBP
cord-016903-z2vqfq98	213	5	the	the	DT
cord-016903-z2vqfq98	213	6	hypothesis	hypothesis	NN
cord-016903-z2vqfq98	213	7	that	that	IN
cord-016903-z2vqfq98	213	8	chronic	chronic	JJ
cord-016903-z2vqfq98	213	9	infection	infection	NN
cord-016903-z2vqfq98	213	10	with	with	IN
cord-016903-z2vqfq98	213	11	the	the	DT
cord-016903-z2vqfq98	213	12	cytomegalovirus	cytomegalovirus	NN
cord-016903-z2vqfq98	213	13	,	,	,
cord-016903-z2vqfq98	213	14	ã	ã	FW
cord-016903-z2vqfq98	213	15	-herpesvirus	-herpesvirus	NNP
cord-016903-z2vqfq98	213	16	,	,	,
cord-016903-z2vqfq98	213	17	may	may	MD
cord-016903-z2vqfq98	213	18	lead	lead	VB
cord-016903-z2vqfq98	213	19	to	to	IN
cord-016903-z2vqfq98	213	20	a	a	DT
cord-016903-z2vqfq98	213	21	decrease	decrease	NN
cord-016903-z2vqfq98	213	22	in	in	IN
cord-016903-z2vqfq98	213	23	the	the	DT
cord-016903-z2vqfq98	213	24	size	size	NN
cord-016903-z2vqfq98	213	25	ofthe	ofthe	DT
cord-016903-z2vqfq98	213	26	naive	naive	JJ
cord-016903-z2vqfq98	213	27	and	and	CC
cord-016903-z2vqfq98	213	28	early	early	JJ
cord-016903-z2vqfq98	213	29	memory	memory	NN
cord-016903-z2vqfq98	213	30	CD8	CD8	NNP
cord-016903-z2vqfq98	213	31	+	+	CC
cord-016903-z2vqfq98	213	32	T	t	NN
cord-016903-z2vqfq98	213	33	-	-	HYPH
cord-016903-z2vqfq98	213	34	cell	cell	NN
cord-016903-z2vqfq98	213	35	pool	pool	NN
cord-016903-z2vqfq98	213	36	,	,	,
cord-016903-z2vqfq98	213	37	but	but	CC
cord-016903-z2vqfq98	213	38	to	to	IN
cord-016903-z2vqfq98	213	39	an	an	DT
cord-016903-z2vqfq98	213	40	increase	increase	NN
cord-016903-z2vqfq98	213	41	in	in	IN
cord-016903-z2vqfq98	213	42	the	the	DT
cord-016903-z2vqfq98	213	43	number	number	NN
cord-016903-z2vqfq98	213	44	of	of	IN
cord-016903-z2vqfq98	213	45	dysfunctional	dysfunctional	JJ
cord-016903-z2vqfq98	213	46	,	,	,
cord-016903-z2vqfq98	213	47	IFNy	ifny	NN
cord-016903-z2vqfq98	213	48	-	-	HYPH
cord-016903-z2vqfq98	213	49	producing	produce	VBG
cord-016903-z2vqfq98	213	50	CD8+CD28-memory	cd8+cd28-memory	VB
cord-016903-z2vqfq98	213	51	-	-	HYPH
cord-016903-z2vqfq98	213	52	effector	effector	JJ
cord-016903-z2vqfq98	213	53	Tvcells	Tvcells	NNP
cord-016903-z2vqfq98	213	54	(	(	-LRB-
cord-016903-z2vqfq98	213	55	Fig	Fig	NNP
cord-016903-z2vqfq98	213	56	.	.	NNP
cord-016903-z2vqfq98	213	57	2	2	CD
cord-016903-z2vqfq98	213	58	)	)	-RRB-
cord-016903-z2vqfq98	213	59	,	,	,
cord-016903-z2vqfq98	213	60	37	37	CD
cord-016903-z2vqfq98	213	61	One	one	CD
cord-016903-z2vqfq98	213	62	clinical	clinical	JJ
cord-016903-z2vqfq98	213	63	consequence	consequence	NN
cord-016903-z2vqfq98	213	64	of	of	IN
cord-016903-z2vqfq98	213	65	the	the	DT
cord-016903-z2vqfq98	213	66	accumulation	accumulation	NN
cord-016903-z2vqfq98	213	67	of	of	IN
cord-016903-z2vqfq98	213	68	CD8+CD28-T	CD8+CD28-T	NNP
cord-016903-z2vqfq98	213	69	-	-	HYPH
cord-016903-z2vqfq98	213	70	cells	cell	NNS
cord-016903-z2vqfq98	213	71	is	be	VBZ
cord-016903-z2vqfq98	213	72	an	an	DT
cord-016903-z2vqfq98	213	73	impaired	impaired	JJ
cord-016903-z2vqfq98	213	74	generation	generation	NN
cord-016903-z2vqfq98	213	75	of	of	IN
cord-016903-z2vqfq98	213	76	protective	protective	JJ
cord-016903-z2vqfq98	213	77	antibody	antibody	NN
cord-016903-z2vqfq98	213	78	levels	level	NNS
cord-016903-z2vqfq98	213	79	after	after	IN
cord-016903-z2vqfq98	213	80	vaccination	vaccination	NN
cord-016903-z2vqfq98	213	81	.	.	.
cord-016903-z2vqfq98	214	1	43.69	43.69	CD
cord-016903-z2vqfq98	215	1	Furthermore	furthermore	RB
cord-016903-z2vqfq98	215	2	,	,	,
cord-016903-z2vqfq98	215	3	the	the	DT
cord-016903-z2vqfq98	215	4	age	age	NN
cord-016903-z2vqfq98	215	5	-	-	HYPH
cord-016903-z2vqfq98	215	6	dependent	dependent	JJ
cord-016903-z2vqfq98	215	7	increase	increase	NN
cord-016903-z2vqfq98	215	8	in	in	IN
cord-016903-z2vqfq98	215	9	the	the	DT
cord-016903-z2vqfq98	215	10	level	level	NN
cord-016903-z2vqfq98	215	11	ofpro	ofpro	JJ
cord-016903-z2vqfq98	215	12	-	-	HYPH
cord-016903-z2vqfq98	215	13	inflammatory	inflammatory	JJ
cord-016903-z2vqfq98	215	14	cyrokines	cyrokine	NNS
cord-016903-z2vqfq98	215	15	may	may	MD
cord-016903-z2vqfq98	215	16	lead	lead	VB
cord-016903-z2vqfq98	215	17	to	to	IN
cord-016903-z2vqfq98	215	18	ubiquitous	ubiquitous	JJ
cord-016903-z2vqfq98	215	19	chronic	chronic	JJ
cord-016903-z2vqfq98	215	20	inflammatory	inflammatory	JJ
cord-016903-z2vqfq98	215	21	responses	response	NNS
cord-016903-z2vqfq98	215	22	in	in	IN
cord-016903-z2vqfq98	215	23	old	old	JJ
cord-016903-z2vqfq98	215	24	age	age	NN
cord-016903-z2vqfq98	215	25	42	42	CD
cord-016903-z2vqfq98	215	26	and	and	CC
cord-016903-z2vqfq98	215	27	may	may	MD
cord-016903-z2vqfq98	215	28	therefore	therefore	RB
cord-016903-z2vqfq98	215	29	support	support	VB
cord-016903-z2vqfq98	215	30	the	the	DT
cord-016903-z2vqfq98	215	31	development	development	NN
cord-016903-z2vqfq98	215	32	of	of	IN
cord-016903-z2vqfq98	215	33	age	age	NN
cord-016903-z2vqfq98	215	34	-	-	HYPH
cord-016903-z2vqfq98	215	35	related	relate	VBN
cord-016903-z2vqfq98	215	36	chronic	chronic	JJ
cord-016903-z2vqfq98	215	37	diseases	disease	NNS
cord-016903-z2vqfq98	215	38	,	,	,
cord-016903-z2vqfq98	215	39	such	such	JJ
cord-016903-z2vqfq98	215	40	as	as	IN
cord-016903-z2vqfq98	215	41	atherosclerosis	atherosclerosis	NN
cord-016903-z2vqfq98	215	42	,	,	.
cord-016903-z2vqfq98	216	1	"	"	``
cord-016903-z2vqfq98	216	2	rheumatoid	rheumatoid	NNP
cord-016903-z2vqfq98	216	3	arthritis	arthritis	NN
cord-016903-z2vqfq98	216	4	"	"	''
cord-016903-z2vqfq98	216	5	and	and	CC
cord-016903-z2vqfq98	216	6	Alzheimer	Alzheimer	NNP
cord-016903-z2vqfq98	216	7	's	's	POS
cord-016903-z2vqfq98	216	8	disease	disease	NN
cord-016903-z2vqfq98	216	9	.	.	.
cord-016903-z2vqfq98	217	1	72	72	CD
cord-016903-z2vqfq98	217	2	,	,	,
cord-016903-z2vqfq98	217	3	73	73	CD
cord-016903-z2vqfq98	218	1	Although	although	IN
cord-016903-z2vqfq98	218	2	individuals	individual	NNS
cord-016903-z2vqfq98	218	3	maintain	maintain	VBP
cord-016903-z2vqfq98	218	4	a	a	DT
cord-016903-z2vqfq98	218	5	relatively	relatively	RB
cord-016903-z2vqfq98	218	6	constant	constant	JJ
cord-016903-z2vqfq98	218	7	total	total	JJ
cord-016903-z2vqfq98	218	8	number	number	NN
cord-016903-z2vqfq98	218	9	ofperipheral	ofperipheral	JJ
cord-016903-z2vqfq98	218	10	B	B	NNP
cord-016903-z2vqfq98	218	11	-	-	HYPH
cord-016903-z2vqfq98	218	12	celIs	celi	VBN
cord-016903-z2vqfq98	218	13	during	during	IN
cord-016903-z2vqfq98	218	14	aging	age	VBG
cord-016903-z2vqfq98	218	15	,	,	,
cord-016903-z2vqfq98	218	16	each	each	DT
cord-016903-z2vqfq98	218	17	B	b	NN
cord-016903-z2vqfq98	218	18	-	-	HYPH
cord-016903-z2vqfq98	218	19	cell	cell	NN
cord-016903-z2vqfq98	218	20	subset	subset	NN
cord-016903-z2vqfq98	218	21	comprises	comprise	VBZ
cord-016903-z2vqfq98	218	22	severeperturbations	severeperturbation	NNS
cord-016903-z2vqfq98	218	23	in	in	IN
cord-016903-z2vqfq98	218	24	size	size	NN
cord-016903-z2vqfq98	218	25	,	,	,
cord-016903-z2vqfq98	218	26	dynamics	dynamic	NNS
cord-016903-z2vqfq98	218	27	and	and	CC
cord-016903-z2vqfq98	218	28	repertoire	repertoire	NN
cord-016903-z2vqfq98	218	29	.	.	.
cord-016903-z2vqfq98	219	1	The	the	DT
cord-016903-z2vqfq98	219	2	alterations	alteration	NNS
cord-016903-z2vqfq98	219	3	affecting	affect	VBG
cord-016903-z2vqfq98	219	4	the	the	DT
cord-016903-z2vqfq98	219	5	Bvcell	Bvcell	NNP
cord-016903-z2vqfq98	219	6	subsets	subset	NNS
cord-016903-z2vqfq98	219	7	are	be	VBP
cord-016903-z2vqfq98	219	8	due	due	JJ
cord-016903-z2vqfq98	219	9	to	to	IN
cord-016903-z2vqfq98	219	10	a	a	DT
cord-016903-z2vqfq98	219	11	decreased	decrease	VBN
cord-016903-z2vqfq98	219	12	generation	generation	NN
cord-016903-z2vqfq98	219	13	ofB	ofb	NN
cord-016903-z2vqfq98	219	14	-	-	HYPH
cord-016903-z2vqfq98	219	15	cell	cell	NN
cord-016903-z2vqfq98	219	16	precursors	precursor	NNS
cord-016903-z2vqfq98	219	17	,	,	,
cord-016903-z2vqfq98	219	18	such	such	JJ
cord-016903-z2vqfq98	219	19	asearly	asearly	JJ
cord-016903-z2vqfq98	219	20	lymphoid	lymphoid	JJ
cord-016903-z2vqfq98	219	21	precursors	precursor	NNS
cord-016903-z2vqfq98	219	22	and	and	CC
cord-016903-z2vqfq98	219	23	pro	pro	JJ
cord-016903-z2vqfq98	219	24	-	-	JJ
cord-016903-z2vqfq98	219	25	Bvcells	Bvcells	NNP
cord-016903-z2vqfq98	219	26	,	,	,
cord-016903-z2vqfq98	219	27	Cell	cell	NN
cord-016903-z2vqfq98	219	28	-	-	HYPH
cord-016903-z2vqfq98	219	29	intrinsic	intrinsic	JJ
cord-016903-z2vqfq98	219	30	as	as	RB
cord-016903-z2vqfq98	219	31	well	well	RB
cord-016903-z2vqfq98	219	32	as	as	IN
cord-016903-z2vqfq98	219	33	micro	micro	JJ
cord-016903-z2vqfq98	219	34	-	-	JJ
cord-016903-z2vqfq98	219	35	environmental	environmental	JJ
cord-016903-z2vqfq98	219	36	disturbances	disturbance	NNS
cord-016903-z2vqfq98	219	37	are	be	VBP
cord-016903-z2vqfq98	219	38	both	both	DT
cord-016903-z2vqfq98	219	39	likely	likely	JJ
cord-016903-z2vqfq98	219	40	to	to	TO
cord-016903-z2vqfq98	219	41	contribute	contribute	VB
cord-016903-z2vqfq98	219	42	to	to	IN
cord-016903-z2vqfq98	219	43	the	the	DT
cord-016903-z2vqfq98	219	44	decreased	decrease	VBN
cord-016903-z2vqfq98	219	45	output	output	NN
cord-016903-z2vqfq98	219	46	ofpro	ofpro	NNP
cord-016903-z2vqfq98	219	47	-	-	HYPH
cord-016903-z2vqfq98	219	48	Bscells	Bscells	NNPS
cord-016903-z2vqfq98	219	49	.	.	.
cord-016903-z2vqfq98	220	1	Furthermore	furthermore	RB
cord-016903-z2vqfq98	220	2	,	,	,
cord-016903-z2vqfq98	220	3	alterations	alteration	NNS
cord-016903-z2vqfq98	220	4	in	in	IN
cord-016903-z2vqfq98	220	5	environmental	environmental	JJ
cord-016903-z2vqfq98	220	6	factors	factor	NNS
cord-016903-z2vqfq98	220	7	also	also	RB
cord-016903-z2vqfq98	220	8	impair	impair	VBP
cord-016903-z2vqfq98	220	9	overall	overall	JJ
cord-016903-z2vqfq98	220	10	V(D)J	V(D)J	NNP
cord-016903-z2vqfq98	220	11	recombinase	recombinase	NN
cord-016903-z2vqfq98	220	12	activity	activity	NN
cord-016903-z2vqfq98	220	13	among	among	IN
cord-016903-z2vqfq98	220	14	pro	pro	JJ
cord-016903-z2vqfq98	220	15	-	-	JJ
cord-016903-z2vqfq98	220	16	Bvcellst'whlch	bvcellst'whlch	JJ
cord-016903-z2vqfq98	220	17	accounts	account	NNS
cord-016903-z2vqfq98	220	18	for	for	IN
cord-016903-z2vqfq98	220	19	the	the	DT
cord-016903-z2vqfq98	220	20	limited	limited	JJ
cord-016903-z2vqfq98	220	21	B	b	NN
cord-016903-z2vqfq98	220	22	-	-	HYPH
cord-016903-z2vqfq98	220	23	cell	cell	NN
cord-016903-z2vqfq98	220	24	repertoire	repertoire	NN
cord-016903-z2vqfq98	221	1	frequendy	frequendy	NNP
cord-016903-z2vqfq98	221	2	detected	detect	VBD
cord-016903-z2vqfq98	221	3	in	in	IN
cord-016903-z2vqfq98	221	4	elderly	elderly	JJ
cord-016903-z2vqfq98	221	5	persons	person	NNS
cord-016903-z2vqfq98	221	6	.	.	.
cord-016903-z2vqfq98	221	7	"	"	''
cord-016903-z2vqfq98	222	1	Although	although	IN
cord-016903-z2vqfq98	222	2	no	no	DT
cord-016903-z2vqfq98	222	3	decrease	decrease	NN
cord-016903-z2vqfq98	222	4	in	in	IN
cord-016903-z2vqfq98	222	5	overall	overall	JJ
cord-016903-z2vqfq98	222	6	serum	serum	NN
cord-016903-z2vqfq98	222	7	immunoglobulin	immunoglobulin	NN
cord-016903-z2vqfq98	222	8	levels	level	NNS
cord-016903-z2vqfq98	222	9	have	have	VBP
cord-016903-z2vqfq98	222	10	been	be	VBN
cord-016903-z2vqfq98	222	11	observed	observe	VBN
cord-016903-z2vqfq98	222	12	during	during	IN
cord-016903-z2vqfq98	222	13	aging	age	VBG
cord-016903-z2vqfq98	222	14	,	,	,
cord-016903-z2vqfq98	222	15	the	the	DT
cord-016903-z2vqfq98	222	16	antibodies	antibody	NNS
cord-016903-z2vqfq98	222	17	generated	generate	VBN
cord-016903-z2vqfq98	222	18	in	in	IN
cord-016903-z2vqfq98	222	19	old	old	JJ
cord-016903-z2vqfq98	222	20	age	age	NN
cord-016903-z2vqfq98	222	21	are	be	VBP
cord-016903-z2vqfq98	222	22	oflower	oflow	JJR
cord-016903-z2vqfq98	222	23	affinity	affinity	NN
cord-016903-z2vqfq98	222	24	due	due	IN
cord-016903-z2vqfq98	222	25	to	to	IN
cord-016903-z2vqfq98	222	26	a	a	DT
cord-016903-z2vqfq98	222	27	shift	shift	NN
cord-016903-z2vqfq98	222	28	in	in	IN
cord-016903-z2vqfq98	222	29	antibody	antibody	NN
cord-016903-z2vqfq98	222	30	isotypes	isotypes	NNP
cord-016903-z2vqfq98	222	31	from	from	IN
cord-016903-z2vqfq98	222	32	IgG	IgG	NNP
cord-016903-z2vqfq98	222	33	to	to	IN
cord-016903-z2vqfq98	222	34	IgM,76	IgM,76	NNP
cord-016903-z2vqfq98	222	35	Of	of	IN
cord-016903-z2vqfq98	222	36	particular	particular	JJ
cord-016903-z2vqfq98	222	37	importance	importance	NN
cord-016903-z2vqfq98	222	38	,	,	,
cord-016903-z2vqfq98	222	39	B	b	NN
cord-016903-z2vqfq98	222	40	-	-	HYPH
cord-016903-z2vqfq98	222	41	celIs	celi	VBN
cord-016903-z2vqfq98	222	42	from	from	IN
cord-016903-z2vqfq98	222	43	elderly	elderly	JJ
cord-016903-z2vqfq98	222	44	individuals	individual	NNS
cord-016903-z2vqfq98	222	45	are	be	VBP
cord-016903-z2vqfq98	222	46	stimulated	stimulate	VBN
cord-016903-z2vqfq98	222	47	70	70	CD
cord-016903-z2vqfq98	222	48	%	%	NN
cord-016903-z2vqfq98	222	49	less	less	CC
cord-016903-z2vqfq98	222	50	efficiendy	efficiendy	VBN
cord-016903-z2vqfq98	222	51	by	by	IN
cord-016903-z2vqfq98	222	52	follicular	follicular	JJ
cord-016903-z2vqfq98	222	53	dendritic	dendritic	JJ
cord-016903-z2vqfq98	222	54	cells	cell	NNS
cord-016903-z2vqfq98	222	55	than	than	IN
cord-016903-z2vqfq98	222	56	Bvcells	Bvcells	NNP
cord-016903-z2vqfq98	222	57	from	from	IN
cord-016903-z2vqfq98	222	58	young	young	JJ
cord-016903-z2vqfq98	222	59	subjects	subject	NNS
cord-016903-z2vqfq98	222	60	,	,	,
cord-016903-z2vqfq98	222	61	"	"	''
cord-016903-z2vqfq98	222	62	suggesting	suggest	VBG
cord-016903-z2vqfq98	222	63	loss	loss	NN
cord-016903-z2vqfq98	222	64	ofB	ofB	NNP
cord-016903-z2vqfq98	222	65	-	-	HYPH
cord-016903-z2vqfq98	222	66	cell	cell	NN
cord-016903-z2vqfq98	222	67	function	function	NN
cord-016903-z2vqfq98	222	68	,	,	,
cord-016903-z2vqfq98	222	69	in	in	IN
cord-016903-z2vqfq98	222	70	part	part	NN
cord-016903-z2vqfq98	222	71	due	due	IN
cord-016903-z2vqfq98	222	72	to	to	IN
cord-016903-z2vqfq98	222	73	the	the	DT
cord-016903-z2vqfq98	222	74	decreased	decrease	VBN
cord-016903-z2vqfq98	222	75	expression	expression	NN
cord-016903-z2vqfq98	222	76	ofcostimulatory	ofcostimulatory	NN
cord-016903-z2vqfq98	222	77	molecules	molecule	NNS
cord-016903-z2vqfq98	222	78	,	,	,
cord-016903-z2vqfq98	222	79	such	such	JJ
cord-016903-z2vqfq98	222	80	as	as	IN
cord-016903-z2vqfq98	222	81	CD40	CD40	NNP
cord-016903-z2vqfq98	222	82	or	or	CC
cord-016903-z2vqfq98	222	83	CD27,78	CD27,78	NNS
cord-016903-z2vqfq98	222	84	Impaired	impair	VBD
cord-016903-z2vqfq98	222	85	T	t	NN
cord-016903-z2vqfq98	222	86	-	-	HYPH
cord-016903-z2vqfq98	222	87	cell	cell	NN
cord-016903-z2vqfq98	222	88	-	-	HYPH
cord-016903-z2vqfq98	222	89	mediated	mediate	VBN
cord-016903-z2vqfq98	222	90	immunity	immunity	NN
cord-016903-z2vqfq98	222	91	as	as	RB
cord-016903-z2vqfq98	222	92	well	well	RB
cord-016903-z2vqfq98	222	93	as	as	IN
cord-016903-z2vqfq98	222	94	defects	defect	NNS
cord-016903-z2vqfq98	222	95	in	in	IN
cord-016903-z2vqfq98	222	96	antigen	antigen	NN
cord-016903-z2vqfq98	222	97	presentation	presentation	NN
cord-016903-z2vqfq98	222	98	by	by	IN
cord-016903-z2vqfq98	222	99	antigen	antigen	NN
cord-016903-z2vqfq98	222	100	presenting	present	VBG
cord-016903-z2vqfq98	222	101	cells	cell	NNS
cord-016903-z2vqfq98	222	102	 	 	_SP
cord-016903-z2vqfq98	223	1	There	there	EX
cord-016903-z2vqfq98	223	2	is	be	VBZ
cord-016903-z2vqfq98	223	3	a	a	DT
cord-016903-z2vqfq98	223	4	tremendous	tremendous	JJ
cord-016903-z2vqfq98	223	5	need	need	NN
cord-016903-z2vqfq98	223	6	to	to	IN
cord-016903-z2vqfq98	223	7	increasethe	increasethe	FW
cord-016903-z2vqfq98	223	8	protective	protective	JJ
cord-016903-z2vqfq98	223	9	effect	effect	NN
cord-016903-z2vqfq98	223	10	ofvaccines	ofvaccine	NNS
cord-016903-z2vqfq98	223	11	in	in	IN
cord-016903-z2vqfq98	223	12	the	the	DT
cord-016903-z2vqfq98	223	13	elderly	elderly	JJ
cord-016903-z2vqfq98	223	14	.	.	.
cord-016903-z2vqfq98	224	1	Research	research	NN
cord-016903-z2vqfq98	224	2	of	of	IN
cord-016903-z2vqfq98	224	3	the	the	DT
cord-016903-z2vqfq98	224	4	last	last	JJ
cord-016903-z2vqfq98	224	5	decade	decade	NN
cord-016903-z2vqfq98	224	6	has	have	VBZ
cord-016903-z2vqfq98	224	7	provided	provide	VBN
cord-016903-z2vqfq98	224	8	new	new	JJ
cord-016903-z2vqfq98	224	9	insights	insight	NNS
cord-016903-z2vqfq98	224	10	into	into	IN
cord-016903-z2vqfq98	224	11	the	the	DT
cord-016903-z2vqfq98	224	12	molecular	molecular	JJ
cord-016903-z2vqfq98	224	13	mechanisms	mechanism	NNS
cord-016903-z2vqfq98	224	14	ofthe	ofthe	DT
cord-016903-z2vqfq98	224	15	immune	immune	JJ
cord-016903-z2vqfq98	224	16	response	response	NN
cord-016903-z2vqfq98	224	17	in	in	IN
cord-016903-z2vqfq98	224	18	old	old	JJ
cord-016903-z2vqfq98	224	19	age	age	NN
cord-016903-z2vqfq98	224	20	,	,	,
cord-016903-z2vqfq98	224	21	which	which	WDT
cord-016903-z2vqfq98	224	22	can	can	MD
cord-016903-z2vqfq98	224	23	now	now	RB
cord-016903-z2vqfq98	224	24	be	be	VB
cord-016903-z2vqfq98	224	25	used	use	VBN
cord-016903-z2vqfq98	224	26	for	for	IN
cord-016903-z2vqfq98	224	27	th	th	XX
cord-016903-z2vqfq98	224	28	e	e	NN
cord-016903-z2vqfq98	224	29	development	development	NN
cord-016903-z2vqfq98	224	30	of	of	IN
cord-016903-z2vqfq98	224	31	potent	potent	JJ
cord-016903-z2vqfq98	224	32	vaccines	vaccine	NNS
cord-016903-z2vqfq98	224	33	.	.	.
cord-016903-z2vqfq98	225	1	In	in	IN
cord-016903-z2vqfq98	225	2	the	the	DT
cord-016903-z2vqfq98	225	3	past	past	NN
cord-016903-z2vqfq98	225	4	,	,	,
cord-016903-z2vqfq98	225	5	vaccines	vaccine	NNS
cord-016903-z2vqfq98	225	6	were	be	VBD
cord-016903-z2vqfq98	225	7	primarily	primarily	RB
cord-016903-z2vqfq98	225	8	designed	design	VBN
cord-016903-z2vqfq98	225	9	to	to	TO
cord-016903-z2vqfq98	225	10	elicit	elicit	VB
cord-016903-z2vqfq98	225	11	a	a	DT
cord-016903-z2vqfq98	225	12	strong	strong	JJ
cord-016903-z2vqfq98	225	13	humoral	humoral	JJ
cord-016903-z2vqfq98	225	14	immune	immune	JJ
cord-016903-z2vqfq98	225	15	response	response	NN
cord-016903-z2vqfq98	225	16	.	.	.
cord-016903-z2vqfq98	226	1	However	however	RB
cord-016903-z2vqfq98	226	2	,	,	,
cord-016903-z2vqfq98	226	3	vaccines	vaccine	NNS
cord-016903-z2vqfq98	226	4	in	in	IN
cord-016903-z2vqfq98	226	5	elderly	elderly	JJ
cord-016903-z2vqfq98	226	6	persons	person	NNS
cord-016903-z2vqfq98	226	7	may	may	MD
cord-016903-z2vqfq98	226	8	be	be	VB
cord-016903-z2vqfq98	226	9	more	more	RBR
cord-016903-z2vqfq98	226	10	effective	effective	JJ
cord-016903-z2vqfq98	227	1	ifthe	ifthe	DT
cord-016903-z2vqfq98	227	2	stimulate	stimulate	VBP
cord-016903-z2vqfq98	227	3	innate	innate	JJ
cord-016903-z2vqfq98	227	4	immune	immune	JJ
cord-016903-z2vqfq98	227	5	components	component	NNS
cord-016903-z2vqfq98	227	6	and	and	CC
cord-016903-z2vqfq98	227	7	the	the	DT
cord-016903-z2vqfq98	227	8	generation	generation	NN
cord-016903-z2vqfq98	227	9	of	of	IN
cord-016903-z2vqfq98	227	10	long	long	RB
cord-016903-z2vqfq98	227	11	-	-	HYPH
cord-016903-z2vqfq98	227	12	lived	live	VBN
cord-016903-z2vqfq98	227	13	memory	memory	NN
cord-016903-z2vqfq98	227	14	T	t	NN
cord-016903-z2vqfq98	227	15	-	-	HYPH
cord-016903-z2vqfq98	227	16	cells	cell	NNS
cord-016903-z2vqfq98	227	17	.	.	.
cord-016903-z2vqfq98	228	1	Currently	currently	RB
cord-016903-z2vqfq98	228	2	,	,	,
cord-016903-z2vqfq98	228	3	severalstrategies	severalstrategie	NNS
cord-016903-z2vqfq98	228	4	are	be	VBP
cord-016903-z2vqfq98	228	5	being	be	VBG
cord-016903-z2vqfq98	228	6	pursued	pursue	VBN
cord-016903-z2vqfq98	228	7	to	to	TO
cord-016903-z2vqfq98	228	8	increase	increase	VB
cord-016903-z2vqfq98	228	9	immunogeniclry	immunogeniclry	NN
cord-016903-z2vqfq98	228	10	,	,	,
cord-016903-z2vqfq98	228	11	to	to	TO
cord-016903-z2vqfq98	228	12	minimize	minimize	VB
cord-016903-z2vqfq98	228	13	adverse	adverse	JJ
cord-016903-z2vqfq98	228	14	side	side	NN
cord-016903-z2vqfq98	228	15	effects	effect	NNS
cord-016903-z2vqfq98	228	16	and	and	CC
cord-016903-z2vqfq98	228	17	to	to	TO
cord-016903-z2vqfq98	228	18	increase	increase	VB
cord-016903-z2vqfq98	228	19	vaccine	vaccine	NN
cord-016903-z2vqfq98	228	20	acceptance	acceptance	NN
cord-016903-z2vqfq98	228	21	by	by	IN
cord-016903-z2vqfq98	228	22	introducing	introduce	VBG
cord-016903-z2vqfq98	228	23	needle	needle	NN
cord-016903-z2vqfq98	228	24	-	-	HYPH
cord-016903-z2vqfq98	228	25	free	free	JJ
cord-016903-z2vqfq98	228	26	injection	injection	NN
cord-016903-z2vqfq98	228	27	devices	device	NNS
cord-016903-z2vqfq98	228	28	.	.	.
cord-016903-z2vqfq98	229	1	Proven	proven	JJ
cord-016903-z2vqfq98	229	2	and	and	CC
cord-016903-z2vqfq98	229	3	promisingvaccine	promisingvaccine	JJ
cord-016903-z2vqfq98	229	4	technologies	technology	NNS
cord-016903-z2vqfq98	229	5	are	be	VBP
cord-016903-z2vqfq98	229	6	used	use	VBN
cord-016903-z2vqfq98	229	7	to	to	TO
cord-016903-z2vqfq98	229	8	design	design	VB
cord-016903-z2vqfq98	229	9	conjugate	conjugate	NN
cord-016903-z2vqfq98	229	10	,	,	,
cord-016903-z2vqfq98	229	11	subunit	subunit	NN
cord-016903-z2vqfq98	229	12	,	,	,
cord-016903-z2vqfq98	229	13	live	live	JJ
cord-016903-z2vqfq98	229	14	vector	vector	NN
cord-016903-z2vqfq98	229	15	,	,	,
cord-016903-z2vqfq98	229	16	DNA	dna	NN
cord-016903-z2vqfq98	229	17	and	and	CC
cord-016903-z2vqfq98	229	18	live	live	RB
cord-016903-z2vqfq98	229	19	-	-	HYPH
cord-016903-z2vqfq98	229	20	attenuated	attenuate	VBN
cord-016903-z2vqfq98	229	21	vaccines	vaccine	NNS
cord-016903-z2vqfq98	229	22	(	(	-LRB-
cord-016903-z2vqfq98	229	23	Table	Table	NNP
cord-016903-z2vqfq98	229	24	3	3	CD
cord-016903-z2vqfq98	229	25	)	)	-RRB-
cord-016903-z2vqfq98	229	26	.80	.80	.
cord-016903-z2vqfq98	230	1	While	while	IN
cord-016903-z2vqfq98	230	2	live	live	RB
cord-016903-z2vqfq98	230	3	-	-	HYPH
cord-016903-z2vqfq98	230	4	attenuated	attenuate	VBN
cord-016903-z2vqfq98	230	5	vaccines	vaccine	NNS
cord-016903-z2vqfq98	230	6	(	(	-LRB-
cord-016903-z2vqfq98	230	7	e.g.•	e.g.•	PRP
cord-016903-z2vqfq98	230	8	against	against	IN
cord-016903-z2vqfq98	230	9	varicella	varicella	NN
cord-016903-z2vqfq98	230	10	,	,	,
cord-016903-z2vqfq98	230	11	measles	measle	NNS
cord-016903-z2vqfq98	230	12	or	or	CC
cord-016903-z2vqfq98	230	13	yellow	yellow	JJ
cord-016903-z2vqfq98	230	14	fever	fever	NN
cord-016903-z2vqfq98	230	15	)	)	-RRB-
cord-016903-z2vqfq98	230	16	stimulate	stimulate	VBP
cord-016903-z2vqfq98	230	17	numerous	numerous	JJ
cord-016903-z2vqfq98	230	18	immune	immune	JJ
cord-016903-z2vqfq98	230	19	components	component	NNS
cord-016903-z2vqfq98	230	20	and	and	CC
cord-016903-z2vqfq98	230	21	display	display	NN
cord-016903-z2vqfq98	230	22	enhanced	enhance	VBN
cord-016903-z2vqfq98	230	23	immunogenicity	immunogenicity	NN
cord-016903-z2vqfq98	230	24	,	,	,
cord-016903-z2vqfq98	230	25	conjugate	conjugate	NN
cord-016903-z2vqfq98	230	26	and	and	CC
cord-016903-z2vqfq98	230	27	subunit	subunit	NN
cord-016903-z2vqfq98	230	28	vaccines	vaccine	NNS
cord-016903-z2vqfq98	230	29	(	(	-LRB-
cord-016903-z2vqfq98	230	30	e.g.	e.g.	RB
cord-016903-z2vqfq98	230	31	,	,	,
cord-016903-z2vqfq98	230	32	against	against	IN
cord-016903-z2vqfq98	230	33	influenza	influenza	NN
cord-016903-z2vqfq98	230	34	)	)	-RRB-
cord-016903-z2vqfq98	230	35	are	be	VBP
cord-016903-z2vqfq98	230	36	often	often	RB
cord-016903-z2vqfq98	230	37	supplemented	supplement	VBN
cord-016903-z2vqfq98	230	38	with	with	IN
cord-016903-z2vqfq98	230	39	adjuvants	adjuvant	NNS
cord-016903-z2vqfq98	230	40	"	"	``
cord-016903-z2vqfq98	230	41	to	to	TO
cord-016903-z2vqfq98	230	42	ensure	ensure	VB
cord-016903-z2vqfq98	230	43	their	-PRON-	PRP$
cord-016903-z2vqfq98	230	44	protective	protective	JJ
cord-016903-z2vqfq98	230	45	effect	effect	NN
cord-016903-z2vqfq98	230	46	.	.	.
cord-016903-z2vqfq98	231	1	Generally	generally	RB
cord-016903-z2vqfq98	231	2	,	,	,
cord-016903-z2vqfq98	231	3	adjuvants	adjuvant	NNS
cord-016903-z2vqfq98	231	4	can	can	MD
cord-016903-z2vqfq98	231	5	be	be	VB
cord-016903-z2vqfq98	231	6	divided	divide	VBN
cord-016903-z2vqfq98	231	7	into	into	IN
cord-016903-z2vqfq98	231	8	antigen	antigen	NN
cord-016903-z2vqfq98	231	9	delivery	delivery	NN
cord-016903-z2vqfq98	231	10	systems	system	NNS
cord-016903-z2vqfq98	231	11	(	(	-LRB-
cord-016903-z2vqfq98	231	12	cationic	cationic	JJ
cord-016903-z2vqfq98	231	13	microparticles	microparticle	NNS
cord-016903-z2vqfq98	231	14	,	,	,
cord-016903-z2vqfq98	231	15	proteasomes	proteasomes	NN
cord-016903-z2vqfq98	231	16	and	and	CC
cord-016903-z2vqfq98	231	17	virus	virus	NN
cord-016903-z2vqfq98	231	18	-	-	HYPH
cord-016903-z2vqfq98	231	19	like	like	JJ
cord-016903-z2vqfq98	231	20	particles	particle	NNS
cord-016903-z2vqfq98	231	21	)	)	-RRB-
cord-016903-z2vqfq98	231	22	and	and	CC
cord-016903-z2vqfq98	231	23	immune	immune	JJ
cord-016903-z2vqfq98	231	24	potentiators	potentiator	NNS
cord-016903-z2vqfq98	231	25	(	(	-LRB-
cord-016903-z2vqfq98	231	26	e.g.•	e.g.•	PRP
cord-016903-z2vqfq98	231	27	cytokines	cytokine	NNS
cord-016903-z2vqfq98	231	28	)	)	-RRB-
cord-016903-z2vqfq98	231	29	.	.	.
cord-016903-z2vqfq98	232	1	These	these	DT
cord-016903-z2vqfq98	232	2	adjuvants	adjuvant	NNS
cord-016903-z2vqfq98	232	3	may	may	MD
cord-016903-z2vqfq98	232	4	overcome	overcome	VB
cord-016903-z2vqfq98	232	5	the	the	DT
cord-016903-z2vqfq98	232	6	proposed	propose	VBN
cord-016903-z2vqfq98	232	7	age	age	NN
cord-016903-z2vqfq98	232	8	-	-	HYPH
cord-016903-z2vqfq98	232	9	related	relate	VBN
cord-016903-z2vqfq98	232	10	functional	functional	JJ
cord-016903-z2vqfq98	232	11	decline	decline	NN
cord-016903-z2vqfq98	232	12	ofinnate	ofinnate	NN
cord-016903-z2vqfq98	232	13	immune	immune	JJ
cord-016903-z2vqfq98	232	14	responses	response	NNS
cord-016903-z2vqfq98	232	15	by	by	IN
cord-016903-z2vqfq98	232	16	targeting	target	VBG
cord-016903-z2vqfq98	232	17	pattern	pattern	NN
cord-016903-z2vqfq98	232	18	-	-	HYPH
cord-016903-z2vqfq98	232	19	recognition	recognition	NN
cord-016903-z2vqfq98	232	20	receptors	receptor	NNS
cord-016903-z2vqfq98	232	21	,	,	,
cord-016903-z2vqfq98	232	22	such	such	JJ
cord-016903-z2vqfq98	232	23	as	as	IN
cord-016903-z2vqfq98	232	24	the	the	DT
cord-016903-z2vqfq98	232	25	recently	recently	RB
cord-016903-z2vqfq98	232	26	identified	identify	VBN
cord-016903-z2vqfq98	232	27	toll	toll	NN
cord-016903-z2vqfq98	232	28	-	-	HYPH
cord-016903-z2vqfq98	232	29	like	like	JJ
cord-016903-z2vqfq98	232	30	receptors	receptor	NNS
cord-016903-z2vqfq98	232	31	or	or	CC
cord-016903-z2vqfq98	232	32	nucleotide	nucleotide	NN
cord-016903-z2vqfq98	232	33	-	-	HYPH
cord-016903-z2vqfq98	232	34	bindingoligomerization	bindingoligomerization	NN
cord-016903-z2vqfq98	232	35	domain	domain	NN
cord-016903-z2vqfq98	232	36	proteins	protein	NNS
cord-016903-z2vqfq98	232	37	.	.	.
cord-016903-z2vqfq98	233	1	"	"	``
cord-016903-z2vqfq98	233	2	The	the	DT
cord-016903-z2vqfq98	233	3	enhanced	enhanced	JJ
cord-016903-z2vqfq98	233	4	activation	activation	NN
cord-016903-z2vqfq98	233	5	ofthe	ofthe	DT
cord-016903-z2vqfq98	233	6	innate	innate	JJ
cord-016903-z2vqfq98	233	7	immune	immune	JJ
cord-016903-z2vqfq98	233	8	system	system	NN
cord-016903-z2vqfq98	233	9	may	may	MD
cord-016903-z2vqfq98	233	10	also	also	RB
cord-016903-z2vqfq98	233	11	improve	improve	VB
cord-016903-z2vqfq98	233	12	antigen	antigen	NN
cord-016903-z2vqfq98	233	13	processing	processing	NN
cord-016903-z2vqfq98	233	14	and	and	CC
cord-016903-z2vqfq98	233	15	presentation	presentation	NN
cord-016903-z2vqfq98	233	16	leading	lead	VBG
cord-016903-z2vqfq98	233	17	to	to	IN
cord-016903-z2vqfq98	233	18	more	more	RBR
cord-016903-z2vqfq98	233	19	potent	potent	JJ
cord-016903-z2vqfq98	233	20	T	t	NN
cord-016903-z2vqfq98	233	21	and	and	CC
cord-016903-z2vqfq98	233	22	B	b	NN
cord-016903-z2vqfq98	233	23	-	-	HYPH
cord-016903-z2vqfq98	233	24	cell	cell	NN
cord-016903-z2vqfq98	233	25	responses	response	NNS
cord-016903-z2vqfq98	233	26	and	and	CC
cord-016903-z2vqfq98	233	27	to	to	IN
cord-016903-z2vqfq98	233	28	sustained	sustain	VBN
cord-016903-z2vqfq98	233	29	immunological	immunological	JJ
cord-016903-z2vqfq98	233	30	memory	memory	NN
cord-016903-z2vqfq98	233	31	.	.	.
cord-016903-z2vqfq98	234	1	Vaccines	vaccine	NNS
cord-016903-z2vqfq98	234	2	supplemented	supplement	VBN
cord-016903-z2vqfq98	234	3	with	with	IN
cord-016903-z2vqfq98	234	4	the	the	DT
cord-016903-z2vqfq98	234	5	DNA	dna	NN
cord-016903-z2vqfq98	234	6	of	of	IN
cord-016903-z2vqfq98	234	7	cytokines	cytokine	NNS
cord-016903-z2vqfq98	234	8	(	(	-LRB-
cord-016903-z2vqfq98	234	9	e.g.	e.g.	RB
cord-016903-z2vqfq98	234	10	,	,	,
cord-016903-z2vqfq98	234	11	IL-2	IL-2	NNP
cord-016903-z2vqfq98	234	12	,	,	,
cord-016903-z2vqfq98	234	13	IL-	IL-	NNP
cord-016903-z2vqfq98	234	14	?	?	.
cord-016903-z2vqfq98	234	15	IL	IL	NNP
cord-016903-z2vqfq98	234	16	-	-	HYPH
cord-016903-z2vqfq98	234	17	I2	I2	NNP
cord-016903-z2vqfq98	234	18	,	,	,
cord-016903-z2vqfq98	234	19	IL	IL	NNP
cord-016903-z2vqfq98	234	20	-	-	HYPH
cord-016903-z2vqfq98	234	21	IS	IS	NNP
cord-016903-z2vqfq98	234	22	or	or	CC
cord-016903-z2vqfq98	234	23	IL-21	IL-21	NNP
cord-016903-z2vqfq98	234	24	)	)	-RRB-
cord-016903-z2vqfq98	234	25	,	,	,
cord-016903-z2vqfq98	234	26	chemokines	chemokine	NNS
cord-016903-z2vqfq98	234	27	or	or	CC
cord-016903-z2vqfq98	234	28	costirnulatory	costirnulatory	NN
cord-016903-z2vqfq98	234	29	molecules	molecule	NNS
cord-016903-z2vqfq98	234	30	may	may	MD
cord-016903-z2vqfq98	234	31	magnify	magnify	VB
cord-016903-z2vqfq98	234	32	immune	immune	JJ
cord-016903-z2vqfq98	234	33	responses	response	NNS
cord-016903-z2vqfq98	234	34	by	by	IN
cord-016903-z2vqfq98	234	35	generating	generate	VBG
cord-016903-z2vqfq98	234	36	more	more	JJR
cord-016903-z2vqfq98	234	37	and	and	CC
cord-016903-z2vqfq98	234	38	long	long	RB
cord-016903-z2vqfq98	234	39	-	-	HYPH
cord-016903-z2vqfq98	234	40	lived	live	VBN
cord-016903-z2vqfq98	234	41	memory	memory	NN
cord-016903-z2vqfq98	234	42	T_ceIIs83	t_ceiis83	NN
cord-016903-z2vqfq98	234	43	-	-	HYPH
cord-016903-z2vqfq98	234	44	85and	85and	NN
cord-016903-z2vqfq98	234	45	may	may	MD
cord-016903-z2vqfq98	234	46	overcome	overcome	VB
cord-016903-z2vqfq98	234	47	immunodominance	immunodominance	NN
cord-016903-z2vqfq98	234	48	.	.	.
cord-016903-z2vqfq98	234	49	'	'	''
cord-016903-z2vqfq98	235	1	"	"	''
cord-016903-z2vqfq98	236	1	In	in	IN
cord-016903-z2vqfq98	236	2	addition	addition	NN
cord-016903-z2vqfq98	236	3	to	to	TO
cord-016903-z2vqfq98	236	4	improve	improve	VB
cord-016903-z2vqfq98	236	5	vaccine	vaccine	NN
cord-016903-z2vqfq98	236	6	efficacy	efficacy	NN
cord-016903-z2vqfq98	236	7	,	,	,
cord-016903-z2vqfq98	236	8	a	a	DT
cord-016903-z2vqfq98	236	9	modification	modification	NN
cord-016903-z2vqfq98	236	10	of	of	IN
cord-016903-z2vqfq98	236	11	vaccination	vaccination	NN
cord-016903-z2vqfq98	236	12	strategies	strategy	NNS
cord-016903-z2vqfq98	236	13	for	for	IN
cord-016903-z2vqfq98	236	14	elderly	elderly	JJ
cord-016903-z2vqfq98	236	15	persons	person	NNS
cord-016903-z2vqfq98	236	16	has	have	VBZ
cord-016903-z2vqfq98	236	17	been	be	VBN
cord-016903-z2vqfq98	236	18	supported	support	VBN
cord-016903-z2vqfq98	236	19	by	by	IN
cord-016903-z2vqfq98	236	20	the	the	DT
cord-016903-z2vqfq98	236	21	results	result	NNS
cord-016903-z2vqfq98	236	22	of	of	IN
cord-016903-z2vqfq98	236	23	several	several	JJ
cord-016903-z2vqfq98	236	24	vaccination	vaccination	NN
cord-016903-z2vqfq98	236	25	trials	trial	NNS
cord-016903-z2vqfq98	236	26	.	.	.
cord-016903-z2vqfq98	237	1	For	for	IN
cord-016903-z2vqfq98	237	2	instance	instance	NN
cord-016903-z2vqfq98	237	3	,	,	,
cord-016903-z2vqfq98	237	4	a	a	DT
cord-016903-z2vqfq98	237	5	decreased	decrease	VBN
cord-016903-z2vqfq98	237	6	response	response	NN
cord-016903-z2vqfq98	237	7	and	and	CC
cord-016903-z2vqfq98	237	8	a	a	DT
cord-016903-z2vqfq98	237	9	shortened	shorten	VBN
cord-016903-z2vqfq98	237	10	duration	duration	NN
cord-016903-z2vqfq98	237	11	ofprotective	ofprotective	NN
cord-016903-z2vqfq98	237	12	immunity	immunity	NN
cord-016903-z2vqfq98	237	13	following	follow	VBG
cord-016903-z2vqfq98	237	14	booster	booster	NN
cord-016903-z2vqfq98	237	15	immunization	immunization	NN
cord-016903-z2vqfq98	237	16	is	be	VBZ
cord-016903-z2vqfq98	237	17	a	a	DT
cord-016903-z2vqfq98	237	18	characteristic	characteristic	JJ
cord-016903-z2vqfq98	237	19	feature	feature	NN
cord-016903-z2vqfq98	237	20	of	of	IN
cord-016903-z2vqfq98	237	21	old	old	JJ
cord-016903-z2vqfq98	237	22	age	age	NN
cord-016903-z2vqfq98	237	23	.	.	.
cord-016903-z2vqfq98	238	1	87Thus	87thus	CD
cord-016903-z2vqfq98	238	2	,	,	,
cord-016903-z2vqfq98	238	3	several	several	JJ
cord-016903-z2vqfq98	238	4	European	european	JJ
cord-016903-z2vqfq98	238	5	health	health	NN
cord-016903-z2vqfq98	238	6	authorities	authority	NNS
cord-016903-z2vqfq98	238	7	have	have	VBP
cord-016903-z2vqfq98	238	8	recommended	recommend	VBN
cord-016903-z2vqfq98	238	9	five	five	CD
cord-016903-z2vqfq98	238	10	-	-	HYPH
cord-016903-z2vqfq98	238	11	year	year	NN
cord-016903-z2vqfq98	238	12	vaccination	vaccination	NN
cord-016903-z2vqfq98	238	13	intervals	interval	NNS
cord-016903-z2vqfq98	238	14	for	for	IN
cord-016903-z2vqfq98	238	15	tetanus	tetanus	NN
cord-016903-z2vqfq98	238	16	,	,	,
cord-016903-z2vqfq98	238	17	diphtheria	diphtheria	NN
cord-016903-z2vqfq98	238	18	,	,	,
cord-016903-z2vqfq98	238	19	pertussis	pertussis	NN
cord-016903-z2vqfq98	238	20	and	and	CC
cord-016903-z2vqfq98	238	21	pneumonia	pneumonia	NN
cord-016903-z2vqfq98	238	22	.	.	.
cord-016903-z2vqfq98	239	1	Increased	increase	VBN
cord-016903-z2vqfq98	239	2	public	public	JJ
cord-016903-z2vqfq98	239	3	awareness	awareness	NN
cord-016903-z2vqfq98	239	4	of	of	IN
cord-016903-z2vqfq98	239	5	regular	regular	JJ
cord-016903-z2vqfq98	239	6	booster	booster	NN
cord-016903-z2vqfq98	239	7	vaccinations	vaccination	NNS
cord-016903-z2vqfq98	239	8	in	in	IN
cord-016903-z2vqfq98	239	9	adults	adult	NNS
cord-016903-z2vqfq98	239	10	should	should	MD
cord-016903-z2vqfq98	239	11	be	be	VB
cord-016903-z2vqfq98	239	12	enforced	enforce	VBN
cord-016903-z2vqfq98	239	13	,	,	,
cord-016903-z2vqfq98	239	14	as	as	IN
cord-016903-z2vqfq98	239	15	these	these	DT
cord-016903-z2vqfq98	239	16	immunization	immunization	NN
cord-016903-z2vqfq98	239	17	regimes	regime	NNS
cord-016903-z2vqfq98	239	18	may	may	MD
cord-016903-z2vqfq98	239	19	be	be	VB
cord-016903-z2vqfq98	239	20	essential	essential	JJ
cord-016903-z2vqfq98	239	21	to	to	TO
cord-016903-z2vqfq98	239	22	maintain	maintain	VB
cord-016903-z2vqfq98	239	23	the	the	DT
cord-016903-z2vqfq98	239	24	ability	ability	NN
cord-016903-z2vqfq98	239	25	to	to	TO
cord-016903-z2vqfq98	239	26	respond	respond	VB
cord-016903-z2vqfq98	239	27	to	to	TO
cord-016903-z2vqfq98	239	28	recall	recall	VB
cord-016903-z2vqfq98	239	29	antigens	antigen	NNS
cord-016903-z2vqfq98	239	30	in	in	IN
cord-016903-z2vqfq98	239	31	old	old	JJ
cord-016903-z2vqfq98	239	32	age	age	NN
cord-016903-z2vqfq98	239	33	.	.	.
cord-016903-z2vqfq98	240	1	Recent	recent	JJ
cord-016903-z2vqfq98	240	2	result	result	NN
cord-016903-z2vqfq98	240	3	s	s	POS
cord-016903-z2vqfq98	240	4	also	also	RB
cord-016903-z2vqfq98	240	5	indicate	indicate	VBP
cord-016903-z2vqfq98	240	6	that	that	IN
cord-016903-z2vqfq98	240	7	long	long	RB
cord-016903-z2vqfq98	240	8	-	-	HYPH
cord-016903-z2vqfq98	240	9	lasting	last	VBG
cord-016903-z2vqfq98	240	10	protection	protection	NN
cord-016903-z2vqfq98	240	11	but	but	CC
cord-016903-z2vqfq98	240	12	also	also	RB
cord-016903-z2vqfq98	240	13	a	a	DT
cord-016903-z2vqfq98	240	14	good	good	JJ
cord-016903-z2vqfq98	240	15	booster	booster	NN
cord-016903-z2vqfq98	240	16	effect	effect	NN
cord-016903-z2vqfq98	240	17	can	can	MD
cord-016903-z2vqfq98	240	18	be	be	VB
cord-016903-z2vqfq98	240	19	expected	expect	VBN
cord-016903-z2vqfq98	240	20	even	even	RB
cord-016903-z2vqfq98	240	21	a	a	DT
cord-016903-z2vqfq98	240	22	long	long	JJ
cord-016903-z2vqfq98	240	23	time	time	NN
cord-016903-z2vqfq98	240	24	after	after	IN
cord-016903-z2vqfq98	240	25	the	the	DT
cord-016903-z2vqfq98	240	26	last	last	JJ
cord-016903-z2vqfq98	240	27	vaccination	vaccination	NN
cord-016903-z2vqfq98	240	28	,	,	,
cord-016903-z2vqfq98	240	29	when	when	WRB
cord-016903-z2vqfq98	240	30	a	a	DT
cord-016903-z2vqfq98	240	31	live	live	RB
cord-016903-z2vqfq98	240	32	-	-	HYPH
cord-016903-z2vqfq98	240	33	attenuated	attenuated	JJ
cord-016903-z2vqfq98	240	34	vaccine	vaccine	NN
cord-016903-z2vqfq98	240	35	(	(	-LRB-
cord-016903-z2vqfq98	240	36	e.g.	e.g.	RB
cord-016903-z2vqfq98	240	37	,	,	,
cord-016903-z2vqfq98	240	38	polio	polio	NN
cord-016903-z2vqfq98	240	39	vaccine	vaccine	NN
cord-016903-z2vqfq98	240	40	)	)	-RRB-
cord-016903-z2vqfq98	240	41	is	be	VBZ
cord-016903-z2vqfq98	240	42	used	use	VBN
cord-016903-z2vqfq98	240	43	for	for	IN
cord-016903-z2vqfq98	240	44	primary	primary	JJ
cord-016903-z2vqfq98	240	45	immunization	immunization	NN
cord-016903-z2vqfq98	240	46	in	in	IN
cord-016903-z2vqfq98	240	47	early	early	JJ
cord-016903-z2vqfq98	240	48	life	life	NN
cord-016903-z2vqfq98	240	49	.	.	.
cord-016903-z2vqfq98	241	1	New	new	JJ
cord-016903-z2vqfq98	241	2	delivery	delivery	NN
cord-016903-z2vqfq98	241	3	systems	system	NNS
cord-016903-z2vqfq98	241	4	that	that	WDT
cord-016903-z2vqfq98	241	5	make	make	VBP
cord-016903-z2vqfq98	241	6	use	use	VB
cord-016903-z2vqfq98	241	7	oftiny	oftiny	NNP
cord-016903-z2vqfq98	241	8	micro	micro	NNS
cord-016903-z2vqfq98	241	9	-	-	HYPH
cord-016903-z2vqfq98	241	10	needles	needle	NNS
cord-016903-z2vqfq98	241	11	or	or	CC
cord-016903-z2vqfq98	241	12	non	non	JJ
cord-016903-z2vqfq98	241	13	-	-	JJ
cord-016903-z2vqfq98	241	14	injectable	injectable	JJ
cord-016903-z2vqfq98	241	15	application	application	NN
cord-016903-z2vqfq98	241	16	devices	device	NNS
cord-016903-z2vqfq98	241	17	(	(	-LRB-
cord-016903-z2vqfq98	241	18	nasal	nasal	NN
cord-016903-z2vqfq98	241	19	,	,	,
cord-016903-z2vqfq98	241	20	oral	oral	JJ
cord-016903-z2vqfq98	241	21	,	,	,
cord-016903-z2vqfq98	241	22	transcutaneous	transcutaneous	JJ
cord-016903-z2vqfq98	241	23	)	)	-RRB-
cord-016903-z2vqfq98	241	24	may	may	MD
cord-016903-z2vqfq98	241	25	further	far	RBR
cord-016903-z2vqfq98	241	26	increase	increase	VB
cord-016903-z2vqfq98	241	27	vaccination	vaccination	NN
cord-016903-z2vqfq98	241	28	acceptance	acceptance	NN
cord-016903-z2vqfq98	241	29	,	,	,
cord-016903-z2vqfq98	241	30	especially	especially	RB
cord-016903-z2vqfq98	241	31	in	in	IN
cord-016903-z2vqfq98	241	32	the	the	DT
cord-016903-z2vqfq98	241	33	case	case	NN
cord-016903-z2vqfq98	241	34	of	of	IN
cord-016903-z2vqfq98	241	35	influenza	influenza	NN
cord-016903-z2vqfq98	241	36	as	as	IN
cord-016903-z2vqfq98	241	37	this	this	DT
cord-016903-z2vqfq98	241	38	vaccination	vaccination	NN
cord-016903-z2vqfq98	241	39	has	have	VBZ
cord-016903-z2vqfq98	241	40	to	to	TO
cord-016903-z2vqfq98	241	41	be	be	VB
cord-016903-z2vqfq98	241	42	repeated	repeat	VBN
cord-016903-z2vqfq98	241	43	annually	annually	RB
cord-016903-z2vqfq98	241	44	.	.	.
cord-016903-z2vqfq98	242	1	Infectious	infectious	JJ
cord-016903-z2vqfq98	242	2	diseases	disease	NNS
cord-016903-z2vqfq98	242	3	in	in	IN
cord-016903-z2vqfq98	242	4	elderly	elderly	JJ
cord-016903-z2vqfq98	242	5	persons	person	NNS
cord-016903-z2vqfq98	242	6	are	be	VBP
cord-016903-z2vqfq98	242	7	becoming	become	VBG
cord-016903-z2vqfq98	242	8	an	an	DT
cord-016903-z2vqfq98	242	9	increasingly	increasingly	RB
cord-016903-z2vqfq98	242	10	importan	importan	JJ
cord-016903-z2vqfq98	242	11	t	t	NN
cord-016903-z2vqfq98	242	12	issue	issue	NN
cord-016903-z2vqfq98	242	13	.	.	.
cord-016903-z2vqfq98	243	1	An	an	DT
cord-016903-z2vqfq98	243	2	utmost	utmost	JJ
cord-016903-z2vqfq98	243	3	need	need	NN
cord-016903-z2vqfq98	243	4	represents	represent	VBZ
cord-016903-z2vqfq98	243	5	the	the	DT
cord-016903-z2vqfq98	243	6	development	development	NN
cord-016903-z2vqfq98	243	7	ofmore	ofmore	IN
cord-016903-z2vqfq98	243	8	immunogenic	immunogenic	JJ
cord-016903-z2vqfq98	243	9	vaccines	vaccine	NNS
cord-016903-z2vqfq98	243	10	for	for	IN
cord-016903-z2vqfq98	243	11	the	the	DT
cord-016903-z2vqfq98	243	12	elderly	elderly	JJ
cord-016903-z2vqfq98	243	13	.	.	.
cord-016903-z2vqfq98	244	1	The	the	DT
cord-016903-z2vqfq98	244	2	improvement	improvement	NN
cord-016903-z2vqfq98	244	3	of	of	IN
cord-016903-z2vqfq98	244	4	specific	specific	JJ
cord-016903-z2vqfq98	244	5	vaccine	vaccine	NN
cord-016903-z2vqfq98	244	6	types	type	NNS
cord-016903-z2vqfq98	244	7	regarding	regard	VBG
cord-016903-z2vqfq98	244	8	immunogenicity	immunogenicity	NN
cord-016903-z2vqfq98	244	9	and	and	CC
cord-016903-z2vqfq98	244	10	tolerability	tolerability	NN
cord-016903-z2vqfq98	244	11	,	,	,
cord-016903-z2vqfq98	244	12	th	th	XX
cord-016903-z2vqfq98	244	13	e	e	NN
cord-016903-z2vqfq98	244	14	addition	addition	NN
cord-016903-z2vqfq98	244	15	of	of	IN
cord-016903-z2vqfq98	244	16	adjuvants	adjuvant	NNS
cord-016903-z2vqfq98	244	17	.	.	.
cord-016903-z2vqfq98	245	1	the	the	DT
cord-016903-z2vqfq98	245	2	design	design	NN
cord-016903-z2vqfq98	245	3	ofnew	ofnew	NNP
cord-016903-z2vqfq98	245	4	delivery	delivery	NN
cord-016903-z2vqfq98	245	5	systems	system	NNS
cord-016903-z2vqfq98	245	6	as	as	RB
cord-016903-z2vqfq98	245	7	well	well	RB
cord-016903-z2vqfq98	245	8	as	as	IN
cord-016903-z2vqfq98	245	9	specific	specific	JJ
cord-016903-z2vqfq98	245	10	immunization	immunization	NN
cord-016903-z2vqfq98	245	11	regimes	regime	NNS
cord-016903-z2vqfq98	245	12	should	should	MD
cord-016903-z2vqfq98	245	13	all	all	RB
cord-016903-z2vqfq98	245	14	contribute	contribute	VB
cord-016903-z2vqfq98	245	15	to	to	IN
cord-016903-z2vqfq98	245	16	an	an	DT
cord-016903-z2vqfq98	245	17	enhanced	enhance	VBN
cord-016903-z2vqfq98	245	18	efficacy	efficacy	NN
cord-016903-z2vqfq98	245	19	ofvaccines	ofvaccines	NNP
cord-016903-z2vqfq98	245	20	in	in	IN
cord-016903-z2vqfq98	245	21	elderl	elderl	NNP
cord-016903-z2vqfq98	245	22	y	y	NNP
cord-016903-z2vqfq98	245	23	persons	person	NNS
cord-016903-z2vqfq98	245	24	.	.	.
cord-016903-z2vqfq98	246	1	Further	further	JJ
cord-016903-z2vqfq98	246	2	improvements	improvement	NNS
cord-016903-z2vqfq98	246	3	may	may	MD
cord-016903-z2vqfq98	246	4	comprise	comprise	VB
cord-016903-z2vqfq98	246	5	the	the	DT
cord-016903-z2vqfq98	246	6	adjustment	adjustment	NN
cord-016903-z2vqfq98	246	7	ofvaccination	ofvaccination	NN
cord-016903-z2vqfq98	246	8	intervals	interval	NNS
cord-016903-z2vqfq98	246	9	in	in	IN
cord-016903-z2vqfq98	246	10	old	old	JJ
cord-016903-z2vqfq98	246	11	age	age	NN
cord-016903-z2vqfq98	246	12	,	,	,
cord-016903-z2vqfq98	246	13	the	the	DT
cord-016903-z2vqfq98	246	14	increase	increase	NN
cord-016903-z2vqfq98	246	15	in	in	IN
cord-016903-z2vqfq98	246	16	vaccine	vaccine	NN
cord-016903-z2vqfq98	246	17	acceptance	acceptance	NN
cord-016903-z2vqfq98	246	18	and	and	CC
cord-016903-z2vqfq98	246	19	vaccination	vaccination	NN
cord-016903-z2vqfq98	246	20	coverage	coverage	NN
cord-016903-z2vqfq98	246	21	as	as	RB
cord-016903-z2vqfq98	246	22	well	well	RB
cord-016903-z2vqfq98	246	23	as	as	IN
cord-016903-z2vqfq98	246	24	raising	raise	VBG
cord-016903-z2vqfq98	246	25	people	people	NNS
cord-016903-z2vqfq98	246	26	's	's	POS
cord-016903-z2vqfq98	246	27	awareness	awareness	NN
cord-016903-z2vqfq98	246	28	to	to	TO
cord-016903-z2vqfq98	246	29	stick	stick	VB
cord-016903-z2vqfq98	246	30	to	to	IN
cord-016903-z2vqfq98	246	31	the	the	DT
cord-016903-z2vqfq98	246	32	recommended	recommend	VBN
cord-016903-z2vqfq98	246	33	booster	booster	NN
cord-016903-z2vqfq98	246	34	vaccination	vaccination	NN
cord-016903-z2vqfq98	246	35	intervals	interval	NNS
cord-016903-z2vqfq98	246	36	throughout	throughout	IN
cord-016903-z2vqfq98	246	37	life	life	NN
cord-016903-z2vqfq98	246	38	.	.	.
cord-016903-z2vqfq98	247	1	In	in	IN
cord-016903-z2vqfq98	247	2	the	the	DT
cord-016903-z2vqfq98	247	3	distant	distant	JJ
cord-016903-z2vqfq98	247	4	future	future	NN
cord-016903-z2vqfq98	247	5	,	,	,
cord-016903-z2vqfq98	247	6	vaccines	vaccine	NNS
cord-016903-z2vqfq98	247	7	may	may	MD
cord-016903-z2vqfq98	247	8	also	also	RB
cord-016903-z2vqfq98	247	9	play	play	VB
cord-016903-z2vqfq98	247	10	an	an	DT
cord-016903-z2vqfq98	247	11	important	important	JJ
cord-016903-z2vqfq98	247	12	role	role	NN
cord-016903-z2vqfq98	247	13	in	in	IN
cord-016903-z2vqfq98	247	14	treating	treat	VBG
cord-016903-z2vqfq98	247	15	non	non	JJ
cord-016903-z2vqfq98	247	16	-	-	JJ
cord-016903-z2vqfq98	247	17	infectious	infectious	JJ
cord-016903-z2vqfq98	247	18	diseases	disease	NNS
cord-016903-z2vqfq98	247	19	such	such	JJ
cord-016903-z2vqfq98	247	20	as	as	IN
cord-016903-z2vqfq98	247	21	allergy	allergy	NN
cord-016903-z2vqfq98	247	22	,	,	,
cord-016903-z2vqfq98	247	23	autoimmunity	autoimmunity	NN
cord-016903-z2vqfq98	247	24	,	,	,
cord-016903-z2vqfq98	247	25	Alzheimer	Alzheimer	NNP
cord-016903-z2vqfq98	247	26	's	's	POS
cord-016903-z2vqfq98	247	27	disease	disease	NN
cord-016903-z2vqfq98	247	28	and	and	CC
cord-016903-z2vqfq98	247	29	cancers	cancer	NNS
cord-016903-z2vqfq98	247	30	.	.	.
cord-016903-z2vqfq98	248	1	Deaths	death	NNS
cord-016903-z2vqfq98	248	2	:	:	:
cord-016903-z2vqfq98	248	3	leading	lead	VBG
cord-016903-z2vqfq98	248	4	causes	cause	NNS
cord-016903-z2vqfq98	248	5	for	for	IN
cord-016903-z2vqfq98	248	6	2002	2002	CD
cord-016903-z2vqfq98	248	7	Social	social	JJ
cord-016903-z2vqfq98	248	8	and	and	CC
cord-016903-z2vqfq98	248	9	environmental	environmental	JJ
cord-016903-z2vqfq98	248	10	risk	risk	NN
cord-016903-z2vqfq98	248	11	factors	factor	NNS
cord-016903-z2vqfq98	248	12	in	in	IN
cord-016903-z2vqfq98	248	13	the	the	DT
cord-016903-z2vqfq98	248	14	emetgence	emetgence	NN
cord-016903-z2vqfq98	248	15	of	of	IN
cord-016903-z2vqfq98	248	16	infectious	infectious	JJ
cord-016903-z2vqfq98	248	17	diseases	disease	NNS
cord-016903-z2vqfq98	249	1	A	a	DT
cord-016903-z2vqfq98	249	2	successful	successful	JJ
cord-016903-z2vqfq98	249	3	eradication	eradication	NN
cord-016903-z2vqfq98	249	4	campaign	campaign	NN
cord-016903-z2vqfq98	249	5	.	.	.
cord-016903-z2vqfq98	250	1	Global	global	JJ
cord-016903-z2vqfq98	250	2	eradication	eradication	NN
cord-016903-z2vqfq98	250	3	of	of	IN
cord-016903-z2vqfq98	250	4	smallpox	smallpox	NN
cord-016903-z2vqfq98	250	5	Survey	Survey	NNP
cord-016903-z2vqfq98	250	6	:	:	:
cord-016903-z2vqfq98	250	7	New	New	NNP
cord-016903-z2vqfq98	250	8	Medicines	medicine	NNS
cord-016903-z2vqfq98	250	9	in	in	IN
cord-016903-z2vqfq98	250	10	development	development	NN
cord-016903-z2vqfq98	250	11	for	for	IN
cord-016903-z2vqfq98	250	12	Infectious	infectious	JJ
cord-016903-z2vqfq98	250	13	diseases	disease	NNS
cord-016903-z2vqfq98	250	14	Ageing	age	VBG
cord-016903-z2vqfq98	250	15	and	and	CC
cord-016903-z2vqfq98	250	16	infection	infection	NN
cord-016903-z2vqfq98	251	1	Pneumonia	pneumonia	NN
cord-016903-z2vqfq98	251	2	and	and	CC
cord-016903-z2vqfq98	251	3	influenza	influenza	NN
cord-016903-z2vqfq98	251	4	deaths	death	NNS
cord-016903-z2vqfq98	251	5	during	during	IN
cord-016903-z2vqfq98	251	6	epidemics	epidemic	NNS
cord-016903-z2vqfq98	251	7	:	:	:
cord-016903-z2vqfq98	251	8	implications	implication	NNS
cord-016903-z2vqfq98	251	9	for	for	IN
cord-016903-z2vqfq98	251	10	prevention	prevention	NN
cord-016903-z2vqfq98	251	11	Influenza	influenza	NN
cord-016903-z2vqfq98	251	12	and	and	CC
cord-016903-z2vqfq98	251	13	pneumococcal	pneumococcal	JJ
cord-016903-z2vqfq98	251	14	vaccination	vaccination	NN
cord-016903-z2vqfq98	251	15	coverage	coverage	NN
cord-016903-z2vqfq98	251	16	among	among	IN
cord-016903-z2vqfq98	251	17	persons	person	NNS
cord-016903-z2vqfq98	251	18	aged	age	VBN
cord-016903-z2vqfq98	252	1	>	>	XX
cord-016903-z2vqfq98	252	2	or	or	CC
cord-016903-z2vqfq98	252	3	=	=	SYM
cord-016903-z2vqfq98	252	4	65	65	CD
cord-016903-z2vqfq98	252	5	years	year	NNS
cord-016903-z2vqfq98	252	6	and	and	CC
cord-016903-z2vqfq98	252	7	persons	person	NNS
cord-016903-z2vqfq98	252	8	aged	age	VBN
cord-016903-z2vqfq98	252	9	18	18	CD
cord-016903-z2vqfq98	252	10	-	-	SYM
cord-016903-z2vqfq98	252	11	64	64	CD
cord-016903-z2vqfq98	252	12	years	year	NNS
cord-016903-z2vqfq98	252	13	with	with	IN
cord-016903-z2vqfq98	252	14	diabetes	diabetes	NN
cord-016903-z2vqfq98	252	15	or	or	CC
cord-016903-z2vqfq98	252	16	asthma	asthma	NN
cord-016903-z2vqfq98	252	17	-	-	HYPH
cord-016903-z2vqfq98	252	18	United	United	NNP
cord-016903-z2vqfq98	252	19	States	States	NNP
cord-016903-z2vqfq98	253	1	The	the	DT
cord-016903-z2vqfq98	253	2	efficacy	efficacy	NN
cord-016903-z2vqfq98	253	3	of	of	IN
cord-016903-z2vqfq98	253	4	influenza	influenza	NN
cord-016903-z2vqfq98	253	5	vaccine	vaccine	NN
cord-016903-z2vqfq98	253	6	in	in	IN
cord-016903-z2vqfq98	253	7	elderly	elderly	JJ
cord-016903-z2vqfq98	253	8	persons	person	NNS
cord-016903-z2vqfq98	253	9	.	.	.
cord-016903-z2vqfq98	254	1	A	a	DT
cord-016903-z2vqfq98	254	2	meta	meta	JJ
cord-016903-z2vqfq98	254	3	-	-	HYPH
cord-016903-z2vqfq98	254	4	analysis	analysis	NN
cord-016903-z2vqfq98	254	5	and	and	CC
cord-016903-z2vqfq98	254	6	review	review	NN
cord-016903-z2vqfq98	254	7	of	of	IN
cord-016903-z2vqfq98	254	8	the	the	DT
cord-016903-z2vqfq98	254	9	literature	literature	NN
cord-016903-z2vqfq98	254	10	Immunity	immunity	NN
cord-016903-z2vqfq98	254	11	and	and	CC
cord-016903-z2vqfq98	254	12	immunization	immunization	NN
cord-016903-z2vqfq98	254	13	in	in	IN
cord-016903-z2vqfq98	254	14	elderly	elderly	JJ
cord-016903-z2vqfq98	255	1	The	the	DT
cord-016903-z2vqfq98	255	2	efficacy	efficacy	NN
cord-016903-z2vqfq98	255	3	and	and	CC
cord-016903-z2vqfq98	255	4	cost	cost	NN
cord-016903-z2vqfq98	255	5	effectiveness	effectiveness	NN
cord-016903-z2vqfq98	255	6	of	of	IN
cord-016903-z2vqfq98	255	7	vaccination	vaccination	NN
cord-016903-z2vqfq98	255	8	against	against	IN
cord-016903-z2vqfq98	255	9	influenza	influenza	NN
cord-016903-z2vqfq98	255	10	among	among	IN
cord-016903-z2vqfq98	255	11	elderly	elderly	JJ
cord-016903-z2vqfq98	255	12	persons	person	NNS
cord-016903-z2vqfq98	255	13	living	live	VBG
cord-016903-z2vqfq98	255	14	in	in	IN
cord-016903-z2vqfq98	255	15	the	the	DT
cord-016903-z2vqfq98	255	16	community	community	NN
cord-016903-z2vqfq98	255	17	Influenza	Influenza	NNP
cord-016903-z2vqfq98	255	18	vaccination	vaccination	NN
cord-016903-z2vqfq98	255	19	programs	program	NNS
cord-016903-z2vqfq98	255	20	for	for	IN
cord-016903-z2vqfq98	255	21	elderly	elderly	JJ
cord-016903-z2vqfq98	255	22	persons	person	NNS
cord-016903-z2vqfq98	255	23	:	:	:
cord-016903-z2vqfq98	255	24	cost	cost	NN
cord-016903-z2vqfq98	255	25	-	-	HYPH
cord-016903-z2vqfq98	255	26	effectiveness	effectiveness	NN
cord-016903-z2vqfq98	255	27	in	in	IN
cord-016903-z2vqfq98	255	28	a	a	DT
cord-016903-z2vqfq98	255	29	health	health	NN
cord-016903-z2vqfq98	255	30	maintenance	maintenance	NN
cord-016903-z2vqfq98	255	31	organization	organization	NN
cord-016903-z2vqfq98	255	32	Reduction	reduction	NN
cord-016903-z2vqfq98	255	33	in	in	IN
cord-016903-z2vqfq98	255	34	mortality	mortality	NN
cord-016903-z2vqfq98	255	35	associated	associate	VBN
cord-016903-z2vqfq98	255	36	with	with	IN
cord-016903-z2vqfq98	255	37	influenza	influenza	JJ
cord-016903-z2vqfq98	255	38	vaccine	vaccine	NN
cord-016903-z2vqfq98	255	39	during	during	IN
cord-016903-z2vqfq98	255	40	1989	1989	CD
cord-016903-z2vqfq98	255	41	-	-	SYM
cord-016903-z2vqfq98	255	42	90	90	CD
cord-016903-z2vqfq98	255	43	epidemic	epidemic	NN
cord-016903-z2vqfq98	255	44	Evidence	evidence	NN
cord-016903-z2vqfq98	255	45	of	of	IN
cord-016903-z2vqfq98	255	46	increased	increase	VBN
cord-016903-z2vqfq98	255	47	clinical	clinical	JJ
cord-016903-z2vqfq98	255	48	protection	protection	NN
cord-016903-z2vqfq98	255	49	of	of	IN
cord-016903-z2vqfq98	255	50	an	an	DT
cord-016903-z2vqfq98	255	51	MF59-adjuvant	mf59-adjuvant	CD
cord-016903-z2vqfq98	255	52	influenza	influenza	NN
cord-016903-z2vqfq98	255	53	vaccine	vaccine	NN
cord-016903-z2vqfq98	255	54	compared	compare	VBN
cord-016903-z2vqfq98	255	55	to	to	IN
cord-016903-z2vqfq98	255	56	a	a	DT
cord-016903-z2vqfq98	255	57	non	non	JJ
cord-016903-z2vqfq98	255	58	-	-	JJ
cord-016903-z2vqfq98	255	59	adjuvant	adjuvant	JJ
cord-016903-z2vqfq98	255	60	vaccine	vaccine	NN
cord-016903-z2vqfq98	255	61	among	among	IN
cord-016903-z2vqfq98	255	62	elderly	elderly	JJ
cord-016903-z2vqfq98	255	63	residents	resident	NNS
cord-016903-z2vqfq98	255	64	of	of	IN
cord-016903-z2vqfq98	255	65	long	long	JJ
cord-016903-z2vqfq98	255	66	-	-	HYPH
cord-016903-z2vqfq98	255	67	term	term	NN
cord-016903-z2vqfq98	255	68	care	care	NN
cord-016903-z2vqfq98	255	69	facilities	facility	NNS
cord-016903-z2vqfq98	255	70	in	in	IN
cord-016903-z2vqfq98	255	71	Italy	Italy	NNP
cord-016903-z2vqfq98	255	72	Immunogenicity	Immunogenicity	NNP
cord-016903-z2vqfq98	255	73	of	of	IN
cord-016903-z2vqfq98	255	74	new	new	JJ
cord-016903-z2vqfq98	255	75	virosome	virosome	NNP
cord-016903-z2vqfq98	255	76	influenza	influenza	NN
cord-016903-z2vqfq98	255	77	vaccine	vaccine	NN
cord-016903-z2vqfq98	255	78	in	in	IN
cord-016903-z2vqfq98	255	79	elderly	elderly	JJ
cord-016903-z2vqfq98	255	80	people	people	NNS
cord-016903-z2vqfq98	255	81	Immunogenicity	Immunogenicity	NNP
cord-016903-z2vqfq98	255	82	of	of	IN
cord-016903-z2vqfq98	255	83	trivalent	trivalent	JJ
cord-016903-z2vqfq98	255	84	subunit	subunit	NN
cord-016903-z2vqfq98	255	85	versus	versus	IN
cord-016903-z2vqfq98	255	86	virosome	virosome	NNP
cord-016903-z2vqfq98	255	87	-	-	HYPH
cord-016903-z2vqfq98	255	88	formulated	formulate	VBN
cord-016903-z2vqfq98	255	89	influenza	influenza	NN
cord-016903-z2vqfq98	255	90	vaccines	vaccine	NNS
cord-016903-z2vqfq98	255	91	in	in	IN
cord-016903-z2vqfq98	255	92	geriatric	geriatric	JJ
cord-016903-z2vqfq98	255	93	patients	patient	NNS
cord-016903-z2vqfq98	255	94	randomized	randomized	JJ
cord-016903-z2vqfq98	255	95	study	study	NN
cord-016903-z2vqfq98	255	96	to	to	TO
cord-016903-z2vqfq98	255	97	compare	compare	VB
cord-016903-z2vqfq98	255	98	the	the	DT
cord-016903-z2vqfq98	255	99	immunogenicity	immunogenicity	NN
cord-016903-z2vqfq98	255	100	and	and	CC
cord-016903-z2vqfq98	255	101	reactogenicity	reactogenicity	NN
cord-016903-z2vqfq98	255	102	of	of	IN
cord-016903-z2vqfq98	255	103	an	an	DT
cord-016903-z2vqfq98	255	104	influenza	influenza	NN
cord-016903-z2vqfq98	255	105	split	split	VBN
cord-016903-z2vqfq98	255	106	vaccine	vaccine	NN
cord-016903-z2vqfq98	255	107	with	with	IN
cord-016903-z2vqfq98	255	108	an	an	DT
cord-016903-z2vqfq98	255	109	MF59adjuvanted	MF59adjuvanted	NNP
cord-016903-z2vqfq98	255	110	subunit	subunit	NN
cord-016903-z2vqfq98	255	111	vaccine	vaccine	NN
cord-016903-z2vqfq98	255	112	and	and	CC
cord-016903-z2vqfq98	255	113	a	a	DT
cord-016903-z2vqfq98	255	114	virosome	virosome	NN
cord-016903-z2vqfq98	255	115	-	-	HYPH
cord-016903-z2vqfq98	255	116	based	base	VBN
cord-016903-z2vqfq98	255	117	subunit	subunit	NN
cord-016903-z2vqfq98	255	118	vaccine	vaccine	NN
cord-016903-z2vqfq98	255	119	in	in	IN
cord-016903-z2vqfq98	255	120	elderly	elderly	JJ
cord-016903-z2vqfq98	255	121	Clinical	clinical	JJ
cord-016903-z2vqfq98	255	122	experience	experience	NN
cord-016903-z2vqfq98	255	123	with	with	IN
cord-016903-z2vqfq98	255	124	inactivated	inactivate	VBN
cord-016903-z2vqfq98	255	125	,	,	,
cord-016903-z2vqfq98	255	126	virosomal	virosomal	VBN
cord-016903-z2vqfq98	255	127	influenza	influenza	NN
cord-016903-z2vqfq98	255	128	vaccine	vaccine	NN
cord-016903-z2vqfq98	256	1	Inactivated	inactivate	VBN
cord-016903-z2vqfq98	256	2	influenza	influenza	NN
cord-016903-z2vqfq98	256	3	virus	virus	NN
cord-016903-z2vqfq98	256	4	vaccines	vaccine	NNS
cord-016903-z2vqfq98	256	5	in	in	IN
cord-016903-z2vqfq98	256	6	children	child	NNS
cord-016903-z2vqfq98	257	1	The	the	DT
cord-016903-z2vqfq98	257	2	Japanese	japanese	JJ
cord-016903-z2vqfq98	257	3	experiencewith	experiencewith	NN
cord-016903-z2vqfq98	257	4	vaccinating	vaccinate	VBG
cord-016903-z2vqfq98	257	5	schoolchildren	schoolchildren	NNS
cord-016903-z2vqfq98	257	6	against	against	IN
cord-016903-z2vqfq98	257	7	influenza	influenza	NN
cord-016903-z2vqfq98	258	1	The	the	DT
cord-016903-z2vqfq98	258	2	23-valent	23-valent	CD
cord-016903-z2vqfq98	258	3	pneumococcal	pneumococcal	JJ
cord-016903-z2vqfq98	258	4	polysaccharide	polysaccharide	NN
cord-016903-z2vqfq98	258	5	vaccine	vaccine	NN
cord-016903-z2vqfq98	258	6	.	.	.
cord-016903-z2vqfq98	259	1	Part	part	NN
cord-016903-z2vqfq98	259	2	1.Efficacyof	1.efficacyof	CD
cord-016903-z2vqfq98	259	3	PPV	PPV	NNP
cord-016903-z2vqfq98	259	4	in	in	IN
cord-016903-z2vqfq98	259	5	the	the	DT
cord-016903-z2vqfq98	259	6	elderly	elderly	JJ
cord-016903-z2vqfq98	259	7	:	:	:
cord-016903-z2vqfq98	259	8	a	a	DT
cord-016903-z2vqfq98	259	9	comparison	comparison	NN
cord-016903-z2vqfq98	259	10	of	of	IN
cord-016903-z2vqfq98	259	11	meta	meta	NNP
cord-016903-z2vqfq98	259	12	-	-	HYPH
cord-016903-z2vqfq98	259	13	analyses	analysis	NNS
cord-016903-z2vqfq98	259	14	Impact	Impact	NNP
cord-016903-z2vqfq98	259	15	of	of	IN
cord-016903-z2vqfq98	259	16	pneumococcal	pneumococcal	JJ
cord-016903-z2vqfq98	259	17	vaccination	vaccination	NN
cord-016903-z2vqfq98	259	18	on	on	IN
cord-016903-z2vqfq98	259	19	morbidity	morbidity	NN
cord-016903-z2vqfq98	259	20	and	and	CC
cord-016903-z2vqfq98	259	21	mortality	mortality	NN
cord-016903-z2vqfq98	259	22	of	of	IN
cord-016903-z2vqfq98	259	23	geriatric	geriatric	JJ
cord-016903-z2vqfq98	259	24	patients	patient	NNS
cord-016903-z2vqfq98	259	25	:	:	:
cord-016903-z2vqfq98	259	26	a	a	DT
cord-016903-z2vqfq98	259	27	case	case	NN
cord-016903-z2vqfq98	259	28	-	-	HYPH
cord-016903-z2vqfq98	259	29	controlled	control	VBN
cord-016903-z2vqfq98	259	30	study	study	NN
cord-016903-z2vqfq98	259	31	Changing	change	VBG
cord-016903-z2vqfq98	259	32	epidemiology	epidemiology	NN
cord-016903-z2vqfq98	259	33	of	of	IN
cord-016903-z2vqfq98	259	34	invasivepneumococcal	invasivepneumococcal	JJ
cord-016903-z2vqfq98	259	35	disease	disease	NN
cord-016903-z2vqfq98	259	36	among	among	IN
cord-016903-z2vqfq98	259	37	older	old	JJR
cord-016903-z2vqfq98	259	38	adults	adult	NNS
cord-016903-z2vqfq98	259	39	in	in	IN
cord-016903-z2vqfq98	259	40	the	the	DT
cord-016903-z2vqfq98	259	41	era	era	NN
cord-016903-z2vqfq98	259	42	of	of	IN
cord-016903-z2vqfq98	259	43	pediatric	pediatric	JJ
cord-016903-z2vqfq98	259	44	pneumococcal	pneumococcal	JJ
cord-016903-z2vqfq98	259	45	conjugate	conjugate	NN
cord-016903-z2vqfq98	259	46	vaccine	vaccine	NN
cord-016903-z2vqfq98	259	47	.	.	.
cord-016903-z2vqfq98	260	1	lama	lama	NNP
cord-016903-z2vqfq98	260	2	Stead	Stead	NNP
cord-016903-z2vqfq98	260	3	ww	ww	XX
cord-016903-z2vqfq98	260	4	:	:	:
cord-016903-z2vqfq98	261	1	Tuberculosis	Tuberculosis	NNP
cord-016903-z2vqfq98	261	2	Tuberculosis	Tuberculosis	NNP
cord-016903-z2vqfq98	261	3	in	in	IN
cord-016903-z2vqfq98	261	4	the	the	DT
cord-016903-z2vqfq98	261	5	elderly	elderly	JJ
cord-016903-z2vqfq98	261	6	AntiTB	AntiTB	NNP
cord-016903-z2vqfq98	261	7	drug	drug	NN
cord-016903-z2vqfq98	261	8	resistance	resistance	NN
cord-016903-z2vqfq98	261	9	in	in	IN
cord-016903-z2vqfq98	261	10	the	the	DT
cord-016903-z2vqfq98	261	11	world	world	NN
cord-016903-z2vqfq98	261	12	Efficacy	Efficacy	NNP
cord-016903-z2vqfq98	261	13	of	of	IN
cord-016903-z2vqfq98	261	14	BCG	BCG	NNP
cord-016903-z2vqfq98	261	15	vaccine	vaccine	NN
cord-016903-z2vqfq98	261	16	in	in	IN
cord-016903-z2vqfq98	261	17	the	the	DT
cord-016903-z2vqfq98	261	18	prevention	prevention	NN
cord-016903-z2vqfq98	261	19	of	of	IN
cord-016903-z2vqfq98	261	20	tuberculosis	tuberculosis	NN
cord-016903-z2vqfq98	261	21	.	.	.
cord-016903-z2vqfq98	262	1	Meta	Meta	NNP
cord-016903-z2vqfq98	262	2	-	-	HYPH
cord-016903-z2vqfq98	262	3	analysis	analysis	NN
cord-016903-z2vqfq98	262	4	of	of	IN
cord-016903-z2vqfq98	262	5	the	the	DT
cord-016903-z2vqfq98	262	6	published	publish	VBN
cord-016903-z2vqfq98	262	7	literature	literature	NN
cord-016903-z2vqfq98	262	8	Colnfection	Colnfection	NNP
cord-016903-z2vqfq98	262	9	with	with	IN
cord-016903-z2vqfq98	262	10	HIV	HIV	NNP
cord-016903-z2vqfq98	262	11	and	and	CC
cord-016903-z2vqfq98	262	12	TB	TB	NNP
cord-016903-z2vqfq98	262	13	:	:	:
cord-016903-z2vqfq98	262	14	double	double	JJ
cord-016903-z2vqfq98	262	15	trouble	trouble	NN
cord-016903-z2vqfq98	263	1	lnununology	lnununology	NN
cord-016903-z2vqfq98	263	2	of	of	IN
cord-016903-z2vqfq98	263	3	tuberculosis	tuberculosis	NN
cord-016903-z2vqfq98	263	4	Population	population	NN
cord-016903-z2vqfq98	263	5	-	-	HYPH
cord-016903-z2vqfq98	263	6	based	base	VBN
cord-016903-z2vqfq98	263	7	study	study	NN
cord-016903-z2vqfq98	263	8	of	of	IN
cord-016903-z2vqfq98	263	9	herpes	herpes	NNP
cord-016903-z2vqfq98	263	10	zoster	zoster	NNP
cord-016903-z2vqfq98	263	11	and	and	CC
cord-016903-z2vqfq98	263	12	its	-PRON-	PRP$
cord-016903-z2vqfq98	263	13	sequelae	sequela	NNS
cord-016903-z2vqfq98	263	14	Varicella	varicella	NN
cord-016903-z2vqfq98	263	15	-	-	HYPH
cord-016903-z2vqfq98	263	16	Zoster	Zoster	NNP
cord-016903-z2vqfq98	263	17	virus	virus	NN
cord-016903-z2vqfq98	263	18	:	:	:
cord-016903-z2vqfq98	263	19	pathogenesis	pathogenesis	NN
cord-016903-z2vqfq98	263	20	,	,	,
cord-016903-z2vqfq98	263	21	immunity	immunity	NN
cord-016903-z2vqfq98	263	22	and	and	CC
cord-016903-z2vqfq98	263	23	clinical	clinical	JJ
cord-016903-z2vqfq98	263	24	management	management	NN
cord-016903-z2vqfq98	263	25	in	in	IN
cord-016903-z2vqfq98	263	26	hematopoietic	hematopoietic	JJ
cord-016903-z2vqfq98	263	27	cell	cell	NN
cord-016903-z2vqfq98	263	28	transplant	transplant	NN
cord-016903-z2vqfq98	263	29	recipients	recipient	NNS
cord-016903-z2vqfq98	263	30	Stress	stress	NN
cord-016903-z2vqfq98	263	31	-	-	HYPH
cord-016903-z2vqfq98	263	32	induced	induce	VBN
cord-016903-z2vqfq98	263	33	subclinical	subclinical	JJ
cord-016903-z2vqfq98	263	34	reactivation	reactivation	NN
cord-016903-z2vqfq98	263	35	of	of	IN
cord-016903-z2vqfq98	263	36	varicella	varicella	NN
cord-016903-z2vqfq98	263	37	zoster	zoster	NN
cord-016903-z2vqfq98	263	38	virus	virus	NN
cord-016903-z2vqfq98	263	39	in	in	IN
cord-016903-z2vqfq98	263	40	astronauts	astronaut	NNS
cord-016903-z2vqfq98	264	1	Live	live	VB
cord-016903-z2vqfq98	265	1	attenuated	attenuated	JJ
cord-016903-z2vqfq98	265	2	varicella	varicella	NN
cord-016903-z2vqfq98	265	3	vaccine	vaccine	NN
cord-016903-z2vqfq98	265	4	Vaccination	Vaccination	NNP
cord-016903-z2vqfq98	265	5	boosts	boost	VBZ
cord-016903-z2vqfq98	265	6	adult	adult	NN
cord-016903-z2vqfq98	265	7	immunity	immunity	NN
cord-016903-z2vqfq98	265	8	to	to	IN
cord-016903-z2vqfq98	265	9	varicella	varicella	NN
cord-016903-z2vqfq98	265	10	zoster	zoster	NNP
cord-016903-z2vqfq98	265	11	virus	virus	NN
cord-016903-z2vqfq98	266	1	A	a	DT
cord-016903-z2vqfq98	266	2	vaccine	vaccine	NN
cord-016903-z2vqfq98	266	3	to	to	TO
cord-016903-z2vqfq98	266	4	prevent	prevent	VB
cord-016903-z2vqfq98	266	5	herpes	herpes	NN
cord-016903-z2vqfq98	266	6	zoster	zoster	NN
cord-016903-z2vqfq98	266	7	and	and	CC
cord-016903-z2vqfq98	266	8	postherpetic	postherpetic	NNP
cord-016903-z2vqfq98	266	9	neuralgia	neuralgia	NN
cord-016903-z2vqfq98	266	10	in	in	IN
cord-016903-z2vqfq98	266	11	older	old	JJR
cord-016903-z2vqfq98	266	12	adults	adult	NNS
cord-016903-z2vqfq98	266	13	Long	long	JJ
cord-016903-z2vqfq98	266	14	-	-	HYPH
cord-016903-z2vqfq98	266	15	term	term	NN
cord-016903-z2vqfq98	266	16	cytomegalovirus	cytomegalovirus	JJ
cord-016903-z2vqfq98	266	17	infection	infection	NN
cord-016903-z2vqfq98	266	18	leads	lead	VBZ
cord-016903-z2vqfq98	266	19	to	to	IN
cord-016903-z2vqfq98	266	20	significant	significant	JJ
cord-016903-z2vqfq98	266	21	changes	change	NNS
cord-016903-z2vqfq98	266	22	in	in	IN
cord-016903-z2vqfq98	266	23	the	the	DT
cord-016903-z2vqfq98	266	24	composition	composition	NN
cord-016903-z2vqfq98	266	25	of	of	IN
cord-016903-z2vqfq98	266	26	the	the	DT
cord-016903-z2vqfq98	266	27	CD8	CD8	NNP
cord-016903-z2vqfq98	266	28	+	+	CC
cord-016903-z2vqfq98	266	29	T	t	NN
cord-016903-z2vqfq98	266	30	-	-	HYPH
cord-016903-z2vqfq98	266	31	cell	cell	NN
cord-016903-z2vqfq98	266	32	repertoire	repertoire	NN
cord-016903-z2vqfq98	266	33	,	,	,
cord-016903-z2vqfq98	266	34	which	which	WDT
cord-016903-z2vqfq98	266	35	may	may	MD
cord-016903-z2vqfq98	266	36	be	be	VB
cord-016903-z2vqfq98	266	37	the	the	DT
cord-016903-z2vqfq98	266	38	basis	basis	NN
cord-016903-z2vqfq98	266	39	for	for	IN
cord-016903-z2vqfq98	266	40	an	an	DT
cord-016903-z2vqfq98	266	41	imbalance	imbalance	NN
cord-016903-z2vqfq98	266	42	in	in	IN
cord-016903-z2vqfq98	266	43	the	the	DT
cord-016903-z2vqfq98	266	44	cyrokine	cyrokine	JJ
cord-016903-z2vqfq98	266	45	production	production	NN
cord-016903-z2vqfq98	266	46	profile	profile	NN
cord-016903-z2vqfq98	266	47	in	in	IN
cord-016903-z2vqfq98	266	48	elderly	elderly	JJ
cord-016903-z2vqfq98	266	49	persons	person	NNS
cord-016903-z2vqfq98	266	50	Human	human	JJ
cord-016903-z2vqfq98	266	51	immunosenescence	immunosenescence	NN
cord-016903-z2vqfq98	266	52	:	:	:
cord-016903-z2vqfq98	266	53	is	be	VBZ
cord-016903-z2vqfq98	266	54	it	-PRON-	PRP
cord-016903-z2vqfq98	266	55	infectious	infectious	JJ
cord-016903-z2vqfq98	266	56	?	?	.
cord-016903-z2vqfq98	267	1	Dysfunctional	dysfunctional	JJ
cord-016903-z2vqfq98	267	2	CMV	CMV	NNP
cord-016903-z2vqfq98	267	3	-	-	HYPH
cord-016903-z2vqfq98	267	4	specific	specific	JJ
cord-016903-z2vqfq98	267	5	CD8	CD8	NNP
cord-016903-z2vqfq98	267	6	+	+	CC
cord-016903-z2vqfq98	267	7	T	T	NNP
cord-016903-z2vqfq98	267	8	-	-	HYPH
cord-016903-z2vqfq98	267	9	cells	cell	NNS
cord-016903-z2vqfq98	267	10	accumulate	accumulate	VBP
cord-016903-z2vqfq98	267	11	in	in	IN
cord-016903-z2vqfq98	267	12	the	the	DT
cord-016903-z2vqfq98	267	13	elderly	elderly	JJ
cord-016903-z2vqfq98	267	14	Cytomegalovirus	Cytomegalovirus	NNP
cord-016903-z2vqfq98	267	15	misleads	mislead	VBZ
cord-016903-z2vqfq98	267	16	its	-PRON-	PRP$
cord-016903-z2vqfq98	267	17	host	host	NN
cord-016903-z2vqfq98	267	18	by	by	IN
cord-016903-z2vqfq98	267	19	priming	prime	VBG
cord-016903-z2vqfq98	267	20	of	of	IN
cord-016903-z2vqfq98	267	21	CD8	CD8	NNP
cord-016903-z2vqfq98	267	22	Tvcclls	Tvcclls	NNP
cord-016903-z2vqfq98	267	23	specific	specific	JJ
cord-016903-z2vqfq98	267	24	for	for	IN
cord-016903-z2vqfq98	267	25	an	an	DT
cord-016903-z2vqfq98	267	26	epirope	epirope	NN
cord-016903-z2vqfq98	267	27	not	not	RB
cord-016903-z2vqfq98	267	28	presented	present	VBN
cord-016903-z2vqfq98	267	29	in	in	IN
cord-016903-z2vqfq98	267	30	infected	infected	JJ
cord-016903-z2vqfq98	267	31	tissues	tissue	NNS
cord-016903-z2vqfq98	267	32	Cytomegalovirus	Cytomegalovirus	NNP
cord-016903-z2vqfq98	267	33	seropositivity	seropositivity	NN
cord-016903-z2vqfq98	267	34	drives	drive	VBZ
cord-016903-z2vqfq98	267	35	the	the	DT
cord-016903-z2vqfq98	267	36	CD8	CD8	NNP
cord-016903-z2vqfq98	267	37	T	T	NNP
cord-016903-z2vqfq98	267	38	-	-	HYPH
cord-016903-z2vqfq98	267	39	cell	cell	NN
cord-016903-z2vqfq98	267	40	repertoire	repertoire	NN
cord-016903-z2vqfq98	267	41	toward	toward	IN
cord-016903-z2vqfq98	267	42	greater	great	JJR
cord-016903-z2vqfq98	267	43	clonaliry	clonaliry	NN
cord-016903-z2vqfq98	267	44	in	in	IN
cord-016903-z2vqfq98	267	45	healthy	healthy	JJ
cord-016903-z2vqfq98	267	46	elderly	elderly	JJ
cord-016903-z2vqfq98	267	47	individuals	individual	NNS
cord-016903-z2vqfq98	267	48	Inllamm	Inllamm	NNP
cord-016903-z2vqfq98	267	49	-	-	HYPH
cord-016903-z2vqfq98	267	50	aging	aging	NN
cord-016903-z2vqfq98	267	51	.	.	.
cord-016903-z2vqfq98	268	1	An	an	DT
cord-016903-z2vqfq98	268	2	evolutionary	evolutionary	JJ
cord-016903-z2vqfq98	268	3	perspective	perspective	NN
cord-016903-z2vqfq98	268	4	on	on	IN
cord-016903-z2vqfq98	268	5	immunosenescence	immunosenescence	NNP
cord-016903-z2vqfq98	268	6	Lack	lack	NN
cord-016903-z2vqfq98	268	7	of	of	IN
cord-016903-z2vqfq98	268	8	antibody	antibody	NN
cord-016903-z2vqfq98	268	9	produ	produ	NNP
cord-016903-z2vqfq98	268	10	ction	ction	NN
cord-016903-z2vqfq98	268	11	following	follow	VBG
cord-016903-z2vqfq98	268	12	immunization	immunization	NN
cord-016903-z2vqfq98	268	13	in	in	IN
cord-016903-z2vqfq98	268	14	old	old	JJ
cord-016903-z2vqfq98	268	15	age	age	NN
cord-016903-z2vqfq98	268	16	:	:	:
cord-016903-z2vqfq98	268	17	association	association	NN
cord-016903-z2vqfq98	268	18	with	with	IN
cord-016903-z2vqfq98	268	19	CD8	CD8	NNP
cord-016903-z2vqfq98	268	20	+	+	SYM
cord-016903-z2vqfq98	268	21	CD28	CD28	NNP
cord-016903-z2vqfq98	268	22	'	'	''
cord-016903-z2vqfq98	268	23	T	t	NN
cord-016903-z2vqfq98	268	24	-	-	HYPH
cord-016903-z2vqfq98	268	25	cell	cell	NN
cord-016903-z2vqfq98	268	26	clonal	clonal	JJ
cord-016903-z2vqfq98	268	27	expansions	expansion	NNS
cord-016903-z2vqfq98	268	28	and	and	CC
cord-016903-z2vqfq98	268	29	an	an	DT
cord-016903-z2vqfq98	268	30	imbalance	imbalance	NN
cord-016903-z2vqfq98	268	31	in	in	IN
cord-016903-z2vqfq98	268	32	the	the	DT
cord-016903-z2vqfq98	268	33	production	production	NN
cord-016903-z2vqfq98	268	34	of	of	IN
cord-016903-z2vqfq98	268	35	Thl	Thl	NNP
cord-016903-z2vqfq98	268	36	and	and	CC
cord-016903-z2vqfq98	268	37	Th2	Th2	NNP
cord-016903-z2vqfq98	268	38	cyrokines	cyrokines	NNP
cord-016903-z2vqfq98	268	39	Restoration	Restoration	NNP
cord-016903-z2vqfq98	268	40	of	of	IN
cord-016903-z2vqfq98	268	41	viral	viral	JJ
cord-016903-z2vqfq98	268	42	immunity	immunity	NN
cord-016903-z2vqfq98	268	43	in	in	IN
cord-016903-z2vqfq98	268	44	immunodeficient	immunodeficient	JJ
cord-016903-z2vqfq98	268	45	humans	human	NNS
cord-016903-z2vqfq98	268	46	by	by	IN
cord-016903-z2vqfq98	268	47	the	the	DT
cord-016903-z2vqfq98	268	48	adoptive	adoptive	JJ
cord-016903-z2vqfq98	268	49	transfer	transfer	NN
cord-016903-z2vqfq98	268	50	ofT	ofT	JJS
cord-016903-z2vqfq98	268	51	-	-	HYPH
cord-016903-z2vqfq98	268	52	cell	cell	NN
cord-016903-z2vqfq98	268	53	clones	clone	NNS
cord-016903-z2vqfq98	268	54	The	the	DT
cord-016903-z2vqfq98	268	55	epidemiology	epidemiology	NN
cord-016903-z2vqfq98	268	56	of	of	IN
cord-016903-z2vqfq98	268	57	pertussis	pertussis	NN
cord-016903-z2vqfq98	268	58	:	:	:
cord-016903-z2vqfq98	268	59	a	a	DT
cord-016903-z2vqfq98	268	60	comparison	comparison	NN
cord-016903-z2vqfq98	268	61	of	of	IN
cord-016903-z2vqfq98	268	62	the	the	DT
cord-016903-z2vqfq98	268	63	epidemiology	epidemiology	NN
cord-016903-z2vqfq98	268	64	of	of	IN
cord-016903-z2vqfq98	268	65	the	the	DT
cord-016903-z2vqfq98	268	66	disease	disease	NN
cord-016903-z2vqfq98	268	67	pertussis	pertussis	NN
cord-016903-z2vqfq98	268	68	with	with	IN
cord-016903-z2vqfq98	268	69	the	the	DT
cord-016903-z2vqfq98	268	70	epidemiology	epidemiology	NN
cord-016903-z2vqfq98	268	71	of	of	IN
cord-016903-z2vqfq98	268	72	Bordetella	Bordetella	NNP
cord-016903-z2vqfq98	268	73	pertussis	pertussis	NN
cord-016903-z2vqfq98	268	74	infection	infection	NN
cord-016903-z2vqfq98	269	1	An	an	DT
cord-016903-z2vqfq98	269	2	epidemic	epidemic	NN
cord-016903-z2vqfq98	269	3	of	of	IN
cord-016903-z2vqfq98	269	4	pertussis	pertussis	NN
cord-016903-z2vqfq98	269	5	among	among	IN
cord-016903-z2vqfq98	269	6	elderly	elderly	JJ
cord-016903-z2vqfq98	269	7	people	people	NNS
cord-016903-z2vqfq98	269	8	in	in	IN
cord-016903-z2vqfq98	269	9	a	a	DT
cord-016903-z2vqfq98	269	10	religious	religious	JJ
cord-016903-z2vqfq98	269	11	institution	institution	NN
cord-016903-z2vqfq98	269	12	in	in	IN
cord-016903-z2vqfq98	269	13	The	the	DT
cord-016903-z2vqfq98	269	14	Netherlands	Netherlands	NNP
cord-016903-z2vqfq98	269	15	Vaccination	Vaccination	NNP
cord-016903-z2vqfq98	269	16	against	against	IN
cord-016903-z2vqfq98	269	17	tetanus	tetanus	NN
cord-016903-z2vqfq98	269	18	in	in	IN
cord-016903-z2vqfq98	269	19	the	the	DT
cord-016903-z2vqfq98	269	20	elderly	elderly	JJ
cord-016903-z2vqfq98	269	21	:	:	:
cord-016903-z2vqfq98	269	22	do	do	VB
cord-016903-z2vqfq98	269	23	recommended	recommend	VBN
cord-016903-z2vqfq98	269	24	vaccination	vaccination	NN
cord-016903-z2vqfq98	269	25	strategies	strategy	NNS
cord-016903-z2vqfq98	269	26	give	give	VBP
cord-016903-z2vqfq98	269	27	sufficient	sufficient	JJ
cord-016903-z2vqfq98	269	28	protection	protection	NN
cord-016903-z2vqfq98	270	1	No	no	DT
cord-016903-z2vqfq98	270	2	immunity	immunity	NN
cord-016903-z2vqfq98	270	3	for	for	IN
cord-016903-z2vqfq98	270	4	the	the	DT
cord-016903-z2vqfq98	270	5	elderly	elderly	JJ
cord-016903-z2vqfq98	270	6	A	A	NNP
cord-016903-z2vqfq98	270	7	population	population	NN
cord-016903-z2vqfq98	270	8	-	-	HYPH
cord-016903-z2vqfq98	270	9	based	base	VBN
cord-016903-z2vqfq98	270	10	serologic	serologic	NNP
cord-016903-z2vqfq98	270	11	survey	survey	NN
cord-016903-z2vqfq98	270	12	of	of	IN
cord-016903-z2vqfq98	270	13	immunity	immunity	NN
cord-016903-z2vqfq98	270	14	to	to	IN
cord-016903-z2vqfq98	270	15	tetanus	tetanus	NN
cord-016903-z2vqfq98	270	16	in	in	IN
cord-016903-z2vqfq98	270	17	the	the	DT
cord-016903-z2vqfq98	270	18	United	United	NNP
cord-016903-z2vqfq98	270	19	States	States	NNP
cord-016903-z2vqfq98	270	20	T	T	NNP
cord-016903-z2vqfq98	270	21	-	-	HYPH
cord-016903-z2vqfq98	270	22	cells	cell	NNS
cord-016903-z2vqfq98	270	23	from	from	IN
cord-016903-z2vqfq98	270	24	elderly	elderly	JJ
cord-016903-z2vqfq98	270	25	persons	person	NNS
cord-016903-z2vqfq98	270	26	respond	respond	VBP
cord-016903-z2vqfq98	270	27	to	to	IN
cord-016903-z2vqfq98	270	28	neoantigenic	neoantigenic	JJ
cord-016903-z2vqfq98	270	29	stimulation	stimulation	NN
cord-016903-z2vqfq98	270	30	with	with	IN
cord-016903-z2vqfq98	270	31	an	an	DT
cord-016903-z2vqfq98	270	32	unimpaired	unimpaired	JJ
cord-016903-z2vqfq98	270	33	IL-2	IL-2	NNP
cord-016903-z2vqfq98	270	34	production	production	NN
cord-016903-z2vqfq98	270	35	and	and	CC
cord-016903-z2vqfq98	270	36	an	an	DT
cord-016903-z2vqfq98	270	37	enhanced	enhance	VBN
cord-016903-z2vqfq98	270	38	differentiation	differentiation	NN
cord-016903-z2vqfq98	270	39	into	into	IN
cord-016903-z2vqfq98	270	40	effector	effector	NN
cord-016903-z2vqfq98	270	41	cells	cell	NNS
cord-016903-z2vqfq98	270	42	Epidemiology	epidemiology	NN
cord-016903-z2vqfq98	270	43	and	and	CC
cord-016903-z2vqfq98	270	44	ecology	ecology	NN
cord-016903-z2vqfq98	270	45	of	of	IN
cord-016903-z2vqfq98	270	46	TBE	TBE	NNP
cord-016903-z2vqfq98	270	47	relevant	relevant	JJ
cord-016903-z2vqfq98	270	48	to	to	IN
cord-016903-z2vqfq98	270	49	the	the	DT
cord-016903-z2vqfq98	270	50	production	production	NN
cord-016903-z2vqfq98	270	51	of	of	IN
cord-016903-z2vqfq98	270	52	effectivevaccines	effectivevaccines	NNP
cord-016903-z2vqfq98	270	53	TBE	TBE	NNP
cord-016903-z2vqfq98	270	54	vaccination	vaccination	NN
cord-016903-z2vqfq98	270	55	and	and	CC
cord-016903-z2vqfq98	270	56	the	the	DT
cord-016903-z2vqfq98	270	57	Austrian	austrian	JJ
cord-016903-z2vqfq98	270	58	experience	experience	NN
cord-016903-z2vqfq98	270	59	Vaccine	Vaccine	NNP
cord-016903-z2vqfq98	270	60	Immunogenicity	Immunogenicity	NNP
cord-016903-z2vqfq98	270	61	and	and	CC
cord-016903-z2vqfq98	270	62	safety	safety	NN
cord-016903-z2vqfq98	270	63	of	of	IN
cord-016903-z2vqfq98	270	64	a	a	DT
cord-016903-z2vqfq98	270	65	booster	booster	NN
cord-016903-z2vqfq98	270	66	vaccination	vaccination	NN
cord-016903-z2vqfq98	270	67	against	against	IN
cord-016903-z2vqfq98	270	68	tick	tick	NN
cord-016903-z2vqfq98	270	69	-	-	HYPH
cord-016903-z2vqfq98	270	70	borne	bear	VBN
cord-016903-z2vqfq98	270	71	encephalitis	encephalitis	RB
cord-016903-z2vqfq98	270	72	more	more	JJR
cord-016903-z2vqfq98	270	73	than	than	IN
cord-016903-z2vqfq98	270	74	3	3	CD
cord-016903-z2vqfq98	270	75	years	year	NNS
cord-016903-z2vqfq98	270	76	following	follow	VBG
cord-016903-z2vqfq98	270	77	the	the	DT
cord-016903-z2vqfq98	270	78	last	last	JJ
cord-016903-z2vqfq98	270	79	immunisation	immunisation	NN
cord-016903-z2vqfq98	270	80	Epidemiology	epidemiology	NN
cord-016903-z2vqfq98	270	81	and	and	CC
cord-016903-z2vqfq98	270	82	prevention	prevention	NN
cord-016903-z2vqfq98	270	83	of	of	IN
cord-016903-z2vqfq98	270	84	hepatitis	hepatitis	NNP
cord-016903-z2vqfq98	270	85	A	A	NNP
cord-016903-z2vqfq98	270	86	in	in	IN
cord-016903-z2vqfq98	270	87	travelers	traveler	NNS
cord-016903-z2vqfq98	270	88	Hepatitis	Hepatitis	NNP
cord-016903-z2vqfq98	270	89	A	A	NNP
cord-016903-z2vqfq98	270	90	and	and	CC
cord-016903-z2vqfq98	270	91	hepatitis	hepatitis	NN
cord-016903-z2vqfq98	270	92	B	b	NN
cord-016903-z2vqfq98	270	93	:	:	:
cord-016903-z2vqfq98	270	94	risks	risk	NNS
cord-016903-z2vqfq98	270	95	compared	compare	VBN
cord-016903-z2vqfq98	270	96	with	with	IN
cord-016903-z2vqfq98	270	97	other	other	JJ
cord-016903-z2vqfq98	270	98	vaccine	vaccine	NN
cord-016903-z2vqfq98	270	99	preventable	preventable	JJ
cord-016903-z2vqfq98	270	100	diseases	disease	NNS
cord-016903-z2vqfq98	270	101	and	and	CC
cord-016903-z2vqfq98	270	102	immunization	immunization	NN
cord-016903-z2vqfq98	270	103	recommendations	recommendation	NNS
cord-016903-z2vqfq98	270	104	A	a	DT
cord-016903-z2vqfq98	270	105	prospective	prospective	JJ
cord-016903-z2vqfq98	270	106	,	,	,
cord-016903-z2vqfq98	270	107	randomized	randomized	JJ
cord-016903-z2vqfq98	270	108	,	,	,
cord-016903-z2vqfq98	270	109	comparative	comparative	JJ
cord-016903-z2vqfq98	270	110	US	US	NNP
cord-016903-z2vqfq98	270	111	trial	trial	NN
cord-016903-z2vqfq98	270	112	of	of	IN
cord-016903-z2vqfq98	270	113	a	a	DT
cord-016903-z2vqfq98	270	114	combination	combination	NN
cord-016903-z2vqfq98	270	115	hepatitis	hepatitis	NN
cord-016903-z2vqfq98	270	116	A	a	NN
cord-016903-z2vqfq98	270	117	and	and	CC
cord-016903-z2vqfq98	270	118	B	B	NNP
cord-016903-z2vqfq98	270	119	vaccine	vaccine	NN
cord-016903-z2vqfq98	270	120	(	(	-LRB-
cord-016903-z2vqfq98	270	121	Twinrix	Twinrix	NNP
cord-016903-z2vqfq98	270	122	)	)	-RRB-
cord-016903-z2vqfq98	270	123	with	with	IN
cord-016903-z2vqfq98	270	124	corresponding	correspond	VBG
cord-016903-z2vqfq98	270	125	monovalent	monovalent	JJ
cord-016903-z2vqfq98	270	126	vaccines	vaccine	NNS
cord-016903-z2vqfq98	270	127	(	(	-LRB-
cord-016903-z2vqfq98	270	128	Havrix	Havrix	NNP
cord-016903-z2vqfq98	270	129	and	and	CC
cord-016903-z2vqfq98	270	130	Engerix	Engerix	NNP
cord-016903-z2vqfq98	270	131	-	-	HYPH
cord-016903-z2vqfq98	270	132	B	B	NNP
cord-016903-z2vqfq98	270	133	)	)	-RRB-
cord-016903-z2vqfq98	270	134	in	in	IN
cord-016903-z2vqfq98	270	135	adults	adult	NNS
cord-016903-z2vqfq98	270	136	Immunogenicity	Immunogenicity	NNP
cord-016903-z2vqfq98	270	137	of	of	IN
cord-016903-z2vqfq98	270	138	an	an	DT
cord-016903-z2vqfq98	270	139	inactivated	inactivate	VBN
cord-016903-z2vqfq98	270	140	hepatitis	hepatitis	NN
cord-016903-z2vqfq98	270	141	A	a	DT
cord-016903-z2vqfq98	270	142	vaccine	vaccine	NN
cord-016903-z2vqfq98	270	143	in	in	IN
cord-016903-z2vqfq98	270	144	Dutch	Dutch	NNP
cord-016903-z2vqfq98	270	145	United	United	NNP
cord-016903-z2vqfq98	270	146	Nations	Nations	NNP
cord-016903-z2vqfq98	270	147	troops	troop	NNS
cord-016903-z2vqfq98	270	148	Immunogenicity	Immunogenicity	NNP
cord-016903-z2vqfq98	270	149	of	of	IN
cord-016903-z2vqfq98	270	150	combined	combine	VBN
cord-016903-z2vqfq98	270	151	hepatitis	hepatitis	NN
cord-016903-z2vqfq98	270	152	A	A	NNP
cord-016903-z2vqfq98	270	153	and	and	CC
cord-016903-z2vqfq98	270	154	B	B	NNP
cord-016903-z2vqfq98	270	155	vaccine	vaccine	NN
cord-016903-z2vqfq98	270	156	in	in	IN
cord-016903-z2vqfq98	270	157	elderly	elderly	JJ
cord-016903-z2vqfq98	270	158	persons	person	NNS
cord-016903-z2vqfq98	271	1	The	the	DT
cord-016903-z2vqfq98	271	2	effect	effect	NN
cord-016903-z2vqfq98	271	3	of	of	IN
cord-016903-z2vqfq98	271	4	age	age	NN
cord-016903-z2vqfq98	271	5	and	and	CC
cord-016903-z2vqfq98	271	6	weight	weight	NN
cord-016903-z2vqfq98	271	7	on	on	IN
cord-016903-z2vqfq98	271	8	the	the	DT
cord-016903-z2vqfq98	271	9	response	response	NN
cord-016903-z2vqfq98	271	10	to	to	IN
cord-016903-z2vqfq98	271	11	formalin	formalin	NN
cord-016903-z2vqfq98	271	12	inactivated	inactivate	VBN
cord-016903-z2vqfq98	271	13	,	,	,
cord-016903-z2vqfq98	271	14	alum	alum	NN
cord-016903-z2vqfq98	271	15	-	-	HYPH
cord-016903-z2vqfq98	271	16	adjuvanted	adjuvante	VBN
cord-016903-z2vqfq98	271	17	hepatitis	hepatitis	NN
cord-016903-z2vqfq98	271	18	A	A	NNP
cord-016903-z2vqfq98	271	19	vaccine	vaccine	NN
cord-016903-z2vqfq98	271	20	in	in	IN
cord-016903-z2vqfq98	271	21	healthy	healthy	JJ
cord-016903-z2vqfq98	271	22	adults	adult	NNS
cord-016903-z2vqfq98	272	1	District	District	NNP
cord-016903-z2vqfq98	272	2	guidelines	guideline	NNS
cord-016903-z2vqfq98	272	3	for	for	IN
cord-016903-z2vqfq98	272	4	yellow	yellow	JJ
cord-016903-z2vqfq98	272	5	fever	fever	NN
cord-016903-z2vqfq98	272	6	surveillance	surveillance	NN
cord-016903-z2vqfq98	272	7	Persistence	persistence	NN
cord-016903-z2vqfq98	272	8	of	of	IN
cord-016903-z2vqfq98	272	9	neutralizing	neutralize	VBG
cord-016903-z2vqfq98	272	10	antibody	antibody	NN
cord-016903-z2vqfq98	272	11	30	30	CD
cord-016903-z2vqfq98	272	12	-	-	SYM
cord-016903-z2vqfq98	272	13	35	35	CD
cord-016903-z2vqfq98	272	14	years	year	NNS
cord-016903-z2vqfq98	272	15	after	after	IN
cord-016903-z2vqfq98	272	16	immunization	immunization	NN
cord-016903-z2vqfq98	272	17	with	with	IN
cord-016903-z2vqfq98	272	18	17D	17d	CD
cord-016903-z2vqfq98	272	19	yellow	yellow	JJ
cord-016903-z2vqfq98	272	20	fever	fever	NN
cord-016903-z2vqfq98	272	21	vaccine	vaccine	NN
cord-016903-z2vqfq98	272	22	Advanced	Advanced	NNP
cord-016903-z2vqfq98	272	23	age	age	NN
cord-016903-z2vqfq98	272	24	a	a	DT
cord-016903-z2vqfq98	272	25	risk	risk	NN
cord-016903-z2vqfq98	272	26	factor	factor	NN
cord-016903-z2vqfq98	272	27	for	for	IN
cord-016903-z2vqfq98	272	28	illness	illness	NN
cord-016903-z2vqfq98	272	29	temporally	temporally	RB
cord-016903-z2vqfq98	272	30	associated	associate	VBN
cord-016903-z2vqfq98	272	31	with	with	IN
cord-016903-z2vqfq98	272	32	yellow	yellow	JJ
cord-016903-z2vqfq98	272	33	fever	fever	NN
cord-016903-z2vqfq98	272	34	vaccination	vaccination	NN
cord-016903-z2vqfq98	272	35	Thymic	Thymic	NNP
cord-016903-z2vqfq98	272	36	involution	involution	NN
cord-016903-z2vqfq98	272	37	in	in	IN
cord-016903-z2vqfq98	272	38	aging	age	VBG
cord-016903-z2vqfq98	272	39	Thymic	Thymic	NNP
cord-016903-z2vqfq98	272	40	involution	involution	NN
cord-016903-z2vqfq98	272	41	with	with	IN
cord-016903-z2vqfq98	272	42	ageing	age	VBG
cord-016903-z2vqfq98	272	43	:	:	:
cord-016903-z2vqfq98	272	44	obsolescence	obsolescence	NN
cord-016903-z2vqfq98	272	45	or	or	CC
cord-016903-z2vqfq98	272	46	good	good	JJ
cord-016903-z2vqfq98	272	47	housekeeping	housekeeping	NN
cord-016903-z2vqfq98	272	48	?	?	.
cord-016903-z2vqfq98	273	1	Age	age	NN
cord-016903-z2vqfq98	273	2	-	-	HYPH
cord-016903-z2vqfq98	273	3	related	relate	VBN
cord-016903-z2vqfq98	273	4	loss	loss	NN
cord-016903-z2vqfq98	273	5	of	of	IN
cord-016903-z2vqfq98	273	6	naive	naive	JJ
cord-016903-z2vqfq98	273	7	T	t	NN
cord-016903-z2vqfq98	273	8	-	-	HYPH
cord-016903-z2vqfq98	273	9	cells	cell	NNS
cord-016903-z2vqfq98	273	10	and	and	CC
cord-016903-z2vqfq98	273	11	dysregulation	dysregulation	NN
cord-016903-z2vqfq98	273	12	of	of	IN
cord-016903-z2vqfq98	273	13	T'-cell/	T'-cell/	NNP
cord-016903-z2vqfq98	273	14	B	b	NN
cord-016903-z2vqfq98	273	15	-	-	HYPH
cord-016903-z2vqfq98	273	16	cell	cell	NN
cord-016903-z2vqfq98	273	17	interactions	interaction	NNS
cord-016903-z2vqfq98	273	18	in	in	IN
cord-016903-z2vqfq98	273	19	human	human	JJ
cord-016903-z2vqfq98	273	20	lymph	lymph	NN
cord-016903-z2vqfq98	273	21	nodes	node	NNS
cord-016903-z2vqfq98	273	22	Marked	mark	VBD
cord-016903-z2vqfq98	273	23	increase	increase	NN
cord-016903-z2vqfq98	273	24	with	with	IN
cord-016903-z2vqfq98	273	25	age	age	NN
cord-016903-z2vqfq98	273	26	of	of	IN
cord-016903-z2vqfq98	273	27	type	type	NN
cord-016903-z2vqfq98	273	28	1	1	CD
cord-016903-z2vqfq98	273	29	cytokines	cytokine	NNS
cord-016903-z2vqfq98	273	30	within	within	IN
cord-016903-z2vqfq98	273	31	memory	memory	NN
cord-016903-z2vqfq98	273	32	and	and	CC
cord-016903-z2vqfq98	273	33	effector	effector	NN
cord-016903-z2vqfq98	274	1	/cytotoxic	/cytotoxic	NFP
cord-016903-z2vqfq98	274	2	CD8	CD8	NNP
cord-016903-z2vqfq98	274	3	+	+	CC
cord-016903-z2vqfq98	274	4	T	T	NNP
cord-016903-z2vqfq98	274	5	-	-	HYPH
cord-016903-z2vqfq98	274	6	cells	cell	NNS
cord-016903-z2vqfq98	274	7	in	in	IN
cord-016903-z2vqfq98	274	8	humans	human	NNS
cord-016903-z2vqfq98	274	9	:	:	:
cord-016903-z2vqfq98	275	1	a	a	DT
cord-016903-z2vqfq98	275	2	contribution	contribution	NN
cord-016903-z2vqfq98	275	3	to	to	TO
cord-016903-z2vqfq98	275	4	understand	understand	VB
cord-016903-z2vqfq98	275	5	the	the	DT
cord-016903-z2vqfq98	275	6	relationship	relationship	NN
cord-016903-z2vqfq98	275	7	between	between	IN
cord-016903-z2vqfq98	275	8	inflammation	inflammation	NN
cord-016903-z2vqfq98	275	9	and	and	CC
cord-016903-z2vqfq98	275	10	immunosenescence	immunosenescence	NN
cord-016903-z2vqfq98	276	1	The	the	DT
cord-016903-z2vqfq98	276	2	aging	aging	NN
cord-016903-z2vqfq98	276	3	of	of	IN
cord-016903-z2vqfq98	276	4	the	the	DT
cord-016903-z2vqfq98	276	5	immune	immune	JJ
cord-016903-z2vqfq98	276	6	system	system	NN
cord-016903-z2vqfq98	276	7	CD8	CD8	NNP
cord-016903-z2vqfq98	276	8	T	T	NNP
cord-016903-z2vqfq98	276	9	-	-	HYPH
cord-016903-z2vqfq98	276	10	cells	cell	NNS
cord-016903-z2vqfq98	276	11	and	and	CC
cord-016903-z2vqfq98	276	12	aging	age	VBG
cord-016903-z2vqfq98	276	13	Value	value	NN
cord-016903-z2vqfq98	276	14	of	of	IN
cord-016903-z2vqfq98	276	15	immunological	immunological	JJ
cord-016903-z2vqfq98	276	16	markers	marker	NNS
cord-016903-z2vqfq98	276	17	in	in	IN
cord-016903-z2vqfq98	276	18	predicting	predict	VBG
cord-016903-z2vqfq98	276	19	responsiveness	responsiveness	NN
cord-016903-z2vqfq98	276	20	to	to	IN
cord-016903-z2vqfq98	276	21	influenza	influenza	NN
cord-016903-z2vqfq98	276	22	vaccination	vaccination	NN
cord-016903-z2vqfq98	276	23	in	in	IN
cord-016903-z2vqfq98	276	24	elderly	elderly	JJ
cord-016903-z2vqfq98	276	25	individuals	individual	NNS
cord-016903-z2vqfq98	276	26	Artherosclerosis	Artherosclerosis	NNP
cord-016903-z2vqfq98	276	27	as	as	IN
cord-016903-z2vqfq98	276	28	an	an	DT
cord-016903-z2vqfq98	276	29	infectious	infectious	JJ
cord-016903-z2vqfq98	276	30	,	,	,
cord-016903-z2vqfq98	276	31	inflammatory	inflammatory	JJ
cord-016903-z2vqfq98	276	32	and	and	CC
cord-016903-z2vqfq98	276	33	autoinunune	autoinunune	JJ
cord-016903-z2vqfq98	276	34	disease	disease	NN
cord-016903-z2vqfq98	276	35	Role	role	NN
cord-016903-z2vqfq98	276	36	of	of	IN
cord-016903-z2vqfq98	276	37	the	the	DT
cord-016903-z2vqfq98	276	38	immune	immune	JJ
cord-016903-z2vqfq98	276	39	system	system	NN
cord-016903-z2vqfq98	276	40	in	in	IN
cord-016903-z2vqfq98	276	41	the	the	DT
cord-016903-z2vqfq98	276	42	pathogenesis	pathogenesis	NN
cord-016903-z2vqfq98	276	43	,	,	,
cord-016903-z2vqfq98	276	44	prevention	prevention	NN
cord-016903-z2vqfq98	276	45	and	and	CC
cord-016903-z2vqfq98	276	46	treatment	treatment	NN
cord-016903-z2vqfq98	276	47	of	of	IN
cord-016903-z2vqfq98	276	48	Alzheimer	Alzheimer	NNP
cord-016903-z2vqfq98	276	49	's	's	POS
cord-016903-z2vqfq98	276	50	disease	disease	NN
cord-016903-z2vqfq98	276	51	How	how	WRB
cord-016903-z2vqfq98	276	52	chronic	chronic	JJ
cord-016903-z2vqfq98	276	53	inflammation	inflammation	NN
cord-016903-z2vqfq98	276	54	can	can	MD
cord-016903-z2vqfq98	276	55	affect	affect	VB
cord-016903-z2vqfq98	276	56	the	the	DT
cord-016903-z2vqfq98	276	57	brain	brain	NN
cord-016903-z2vqfq98	276	58	and	and	CC
cord-016903-z2vqfq98	276	59	support	support	VB
cord-016903-z2vqfq98	276	60	the	the	DT
cord-016903-z2vqfq98	276	61	development	development	NN
cord-016903-z2vqfq98	276	62	of	of	IN
cord-016903-z2vqfq98	276	63	Alzheimer	Alzheimer	NNP
cord-016903-z2vqfq98	276	64	's	's	POS
cord-016903-z2vqfq98	276	65	disease	disease	NN
cord-016903-z2vqfq98	276	66	in	in	IN
cord-016903-z2vqfq98	276	67	old	old	JJ
cord-016903-z2vqfq98	276	68	age	age	NN
cord-016903-z2vqfq98	276	69	:	:	:
cord-016903-z2vqfq98	276	70	the	the	DT
cord-016903-z2vqfq98	276	71	role	role	NN
cord-016903-z2vqfq98	276	72	of	of	IN
cord-016903-z2vqfq98	276	73	microglia	microglia	NN
cord-016903-z2vqfq98	276	74	and	and	CC
cord-016903-z2vqfq98	276	75	astrocytes	astrocyte	VBZ
cord-016903-z2vqfq98	276	76	Bone	bone	NN
cord-016903-z2vqfq98	276	77	marrow	marrow	NN
cord-016903-z2vqfq98	276	78	microenvironmental	microenvironmental	NN
cord-016903-z2vqfq98	276	79	changes	change	NNS
cord-016903-z2vqfq98	276	80	underlie	underlie	VBP
cord-016903-z2vqfq98	276	81	reduced	reduce	VBN
cord-016903-z2vqfq98	276	82	RAG	rag	NN
cord-016903-z2vqfq98	276	83	-	-	HYPH
cord-016903-z2vqfq98	276	84	mediated	mediate	VBN
cord-016903-z2vqfq98	276	85	recombination	recombination	NN
cord-016903-z2vqfq98	276	86	and	and	CC
cord-016903-z2vqfq98	276	87	Bvcell	Bvcell	NNP
cord-016903-z2vqfq98	276	88	generation	generation	NN
cord-016903-z2vqfq98	276	89	in	in	IN
cord-016903-z2vqfq98	276	90	aged	aged	JJ
cord-016903-z2vqfq98	276	91	mice	mouse	NNS
cord-016903-z2vqfq98	277	1	The	the	DT
cord-016903-z2vqfq98	277	2	effect	effect	NN
cord-016903-z2vqfq98	277	3	of	of	IN
cord-016903-z2vqfq98	277	4	age	age	NN
cord-016903-z2vqfq98	277	5	on	on	IN
cord-016903-z2vqfq98	277	6	the	the	DT
cord-016903-z2vqfq98	277	7	B	b	NN
cord-016903-z2vqfq98	277	8	-	-	HYPH
cord-016903-z2vqfq98	277	9	cell	cell	NN
cord-016903-z2vqfq98	277	10	repertoire	repertoire	NN
cord-016903-z2vqfq98	277	11	Ageing	age	VBG
cord-016903-z2vqfq98	277	12	,	,	,
cord-016903-z2vqfq98	277	13	autoimmunity	autoimmunity	NN
cord-016903-z2vqfq98	277	14	and	and	CC
cord-016903-z2vqfq98	277	15	arthritis	arthritis	NN
cord-016903-z2vqfq98	277	16	:	:	:
cord-016903-z2vqfq98	277	17	senescence	senescence	NN
cord-016903-z2vqfq98	277	18	of	of	IN
cord-016903-z2vqfq98	277	19	the	the	DT
cord-016903-z2vqfq98	277	20	B	b	NN
cord-016903-z2vqfq98	277	21	-	-	HYPH
cord-016903-z2vqfq98	277	22	cell	cell	NN
cord-016903-z2vqfq98	277	23	compartment	compartment	NN
cord-016903-z2vqfq98	277	24	-implications	-implication	NNS
cord-016903-z2vqfq98	277	25	for	for	IN
cord-016903-z2vqfq98	277	26	humoral	humoral	JJ
cord-016903-z2vqfq98	277	27	immunity	immunity	NN
cord-016903-z2vqfq98	277	28	Age	Age	NNP
cord-016903-z2vqfq98	277	29	-	-	HYPH
cord-016903-z2vqfq98	277	30	related	relate	VBN
cord-016903-z2vqfq98	277	31	depression	depression	NN
cord-016903-z2vqfq98	277	32	of	of	IN
cord-016903-z2vqfq98	277	33	FDC	FDC	NNP
cord-016903-z2vqfq98	277	34	accessory	accessory	NN
cord-016903-z2vqfq98	277	35	functions	function	NNS
cord-016903-z2vqfq98	277	36	and	and	CC
cord-016903-z2vqfq98	277	37	CD21	CD21	NNP
cord-016903-z2vqfq98	277	38	ligand	ligand	NN
cord-016903-z2vqfq98	277	39	-	-	HYPH
cord-016903-z2vqfq98	277	40	mediated	mediate	VBN
cord-016903-z2vqfq98	277	41	repair	repair	NN
cord-016903-z2vqfq98	277	42	of	of	IN
cord-016903-z2vqfq98	277	43	costimulation	costimulation	NN
cord-016903-z2vqfq98	277	44	B	b	NN
cord-016903-z2vqfq98	277	45	-	-	HYPH
cord-016903-z2vqfq98	277	46	cells	cell	NNS
cord-016903-z2vqfq98	277	47	in	in	IN
cord-016903-z2vqfq98	277	48	the	the	DT
cord-016903-z2vqfq98	277	49	aged	aged	JJ
cord-016903-z2vqfq98	277	50	:	:	:
cord-016903-z2vqfq98	277	51	CD27	CD27	NNP
cord-016903-z2vqfq98	277	52	,	,	,
cord-016903-z2vqfq98	277	53	CDS	CDS	NNP
cord-016903-z2vqfq98	277	54	and	and	CC
cord-016903-z2vqfq98	277	55	CD40	CD40	NNP
cord-016903-z2vqfq98	277	56	expression	expression	NN
cord-016903-z2vqfq98	277	57	Ineffective	ineffective	JJ
cord-016903-z2vqfq98	277	58	humoral	humoral	JJ
cord-016903-z2vqfq98	277	59	immunity	immunity	NN
cord-016903-z2vqfq98	277	60	in	in	IN
cord-016903-z2vqfq98	277	61	the	the	DT
cord-016903-z2vqfq98	277	62	elderly	elderly	JJ
cord-016903-z2vqfq98	277	63	Vaccine	Vaccine	NNP
cord-016903-z2vqfq98	277	64	development	development	NN
cord-016903-z2vqfq98	277	65	strategies	strategy	NNS
cord-016903-z2vqfq98	277	66	for	for	IN
cord-016903-z2vqfq98	277	67	improving	improve	VBG
cord-016903-z2vqfq98	277	68	immunization	immunization	NN
cord-016903-z2vqfq98	277	69	:	:	:
cord-016903-z2vqfq98	277	70	the	the	DT
cord-016903-z2vqfq98	277	71	role	role	NN
cord-016903-z2vqfq98	277	72	of	of	IN
cord-016903-z2vqfq98	277	73	modem	modem	NNP
cord-016903-z2vqfq98	277	74	immunology	immunology	NNP
cord-016903-z2vqfq98	277	75	Survey	Survey	NNP
cord-016903-z2vqfq98	277	76	of	of	IN
cord-016903-z2vqfq98	277	77	human	human	JJ
cord-016903-z2vqfq98	277	78	-	-	HYPH
cord-016903-z2vqfq98	277	79	use	use	NN
cord-016903-z2vqfq98	277	80	adjuvants	adjuvant	NNS
cord-016903-z2vqfq98	277	81	Targeting	target	VBG
cord-016903-z2vqfq98	277	82	the	the	DT
cord-016903-z2vqfq98	277	83	innate	innate	JJ
cord-016903-z2vqfq98	277	84	immune	immune	JJ
cord-016903-z2vqfq98	277	85	response	response	NN
cord-016903-z2vqfq98	277	86	with	with	IN
cord-016903-z2vqfq98	277	87	improved	improved	JJ
cord-016903-z2vqfq98	277	88	vaccine	vaccine	NN
cord-016903-z2vqfq98	277	89	adjuvants	adjuvant	NNS
cord-016903-z2vqfq98	277	90	Augmentation	augmentation	NN
cord-016903-z2vqfq98	277	91	and	and	CC
cord-016903-z2vqfq98	277	92	suppression	suppression	NN
cord-016903-z2vqfq98	277	93	of	of	IN
cord-016903-z2vqfq98	277	94	immune	immune	JJ
cord-016903-z2vqfq98	277	95	responses	response	NNS
cord-016903-z2vqfq98	277	96	to	to	IN
cord-016903-z2vqfq98	277	97	an	an	DT
cord-016903-z2vqfq98	277	98	HIV	HIV	NNP
cord-016903-z2vqfq98	277	99	-	-	HYPH
cord-016903-z2vqfq98	277	100	l	l	NNP
cord-016903-z2vqfq98	277	101	DNA	DNA	NNP
cord-016903-z2vqfq98	277	102	vaccine	vaccine	NN
cord-016903-z2vqfq98	277	103	by	by	IN
cord-016903-z2vqfq98	277	104	plasmid	plasmid	NN
cord-016903-z2vqfq98	277	105	cytokine	cytokine	NN
cord-016903-z2vqfq98	277	106	/	/	SYM
cord-016903-z2vqfq98	277	107	Ig	Ig	NNP
cord-016903-z2vqfq98	277	108	administration	administration	NN
cord-016903-z2vqfq98	277	109	Coimmunization	Coimmunization	NNP
cord-016903-z2vqfq98	277	110	with	with	IN
cord-016903-z2vqfq98	277	111	an	an	DT
cord-016903-z2vqfq98	277	112	optimized	optimize	VBN
cord-016903-z2vqfq98	277	113	IL-15	IL-15	NNP
cord-016903-z2vqfq98	277	114	plasmid	plasmid	NN
cord-016903-z2vqfq98	277	115	results	result	NNS
cord-016903-z2vqfq98	277	116	in	in	IN
cord-016903-z2vqfq98	277	117	enhanced	enhanced	JJ
cord-016903-z2vqfq98	277	118	function	function	NN
cord-016903-z2vqfq98	277	119	and	and	CC
cord-016903-z2vqfq98	277	120	longevity	longevity	NN
cord-016903-z2vqfq98	277	121	of	of	IN
cord-016903-z2vqfq98	277	122	CD8	CD8	NNP
cord-016903-z2vqfq98	277	123	T	T	NNP
cord-016903-z2vqfq98	277	124	-	-	HYPH
cord-016903-z2vqfq98	277	125	cells	cell	NNS
cord-016903-z2vqfq98	277	126	that	that	WDT
cord-016903-z2vqfq98	277	127	are	be	VBP
cord-016903-z2vqfq98	277	128	partially	partially	RB
cord-016903-z2vqfq98	277	129	independent	independent	JJ
cord-016903-z2vqfq98	277	130	of	of	IN
cord-016903-z2vqfq98	277	131	CD4	CD4	NNP
cord-016903-z2vqfq98	277	132	T	T	NNP
cord-016903-z2vqfq98	277	133	-	-	HYPH
cord-016903-z2vqfq98	277	134	cell	cell	NN
cord-016903-z2vqfq98	277	135	help	help	NN
cord-016903-z2vqfq98	278	1	IL-21	IL-21	NNP
cord-016903-z2vqfq98	278	2	influences	influence	VBZ
cord-016903-z2vqfq98	278	3	the	the	DT
cord-016903-z2vqfq98	278	4	frequency	frequency	NN
cord-016903-z2vqfq98	278	5	,	,	,
cord-016903-z2vqfq98	278	6	phenotype	phenotype	NN
cord-016903-z2vqfq98	278	7	and	and	CC
cord-016903-z2vqfq98	278	8	affinity	affinity	NN
cord-016903-z2vqfq98	278	9	of	of	IN
cord-016903-z2vqfq98	278	10	the	the	DT
cord-016903-z2vqfq98	278	11	antigen	antigen	NN
cord-016903-z2vqfq98	278	12	-	-	HYPH
cord-016903-z2vqfq98	278	13	specific	specific	JJ
cord-016903-z2vqfq98	278	14	CD8	CD8	NNP
cord-016903-z2vqfq98	278	15	T	t	NN
cord-016903-z2vqfq98	278	16	-	-	HYPH
cord-016903-z2vqfq98	278	17	cell	cell	NN
cord-016903-z2vqfq98	278	18	response	response	NN
cord-016903-z2vqfq98	278	19	Adjuvant	Adjuvant	NNP
cord-016903-z2vqfq98	278	20	IL7	IL7	NNS
cord-016903-z2vqfq98	278	21	or	or	CC
cord-016903-z2vqfq98	278	22	IL-15	IL-15	NNP
cord-016903-z2vqfq98	278	23	overcomes	overcome	VBZ
cord-016903-z2vqfq98	278	24	immunodominance	immunodominance	NN
cord-016903-z2vqfq98	278	25	and	and	CC
cord-016903-z2vqfq98	278	26	improves	improve	VBZ
cord-016903-z2vqfq98	278	27	survival	survival	NN
cord-016903-z2vqfq98	278	28	of	of	IN
cord-016903-z2vqfq98	278	29	the	the	DT
cord-016903-z2vqfq98	278	30	CD8	CD8	NNP
cord-016903-z2vqfq98	278	31	+	+	CC
cord-016903-z2vqfq98	278	32	memory	memory	NN
cord-016903-z2vqfq98	278	33	cell	cell	NN
cord-016903-z2vqfq98	278	34	pool	pool	NN
cord-016903-z2vqfq98	279	1	Insufficient	insufficient	JJ
cord-016903-z2vqfq98	279	2	protection	protection	NN
cord-016903-z2vqfq98	279	3	for	for	IN
cord-016903-z2vqfq98	279	4	healthy	healthy	JJ
cord-016903-z2vqfq98	279	5	elderly	elderly	JJ
cord-016903-z2vqfq98	279	6	adults	adult	NNS
cord-016903-z2vqfq98	279	7	by	by	IN
cord-016903-z2vqfq98	279	8	tetanus	tetanus	NN
cord-016903-z2vqfq98	279	9	and	and	CC
cord-016903-z2vqfq98	279	10	TBE	TBE	NNP
cord-016903-z2vqfq98	279	11	vaccines	vaccine	NNS
cord-016903-z2vqfq98	279	12	Immunizations	immunization	NNS
cord-016903-z2vqfq98	279	13	in	in	IN
cord-016903-z2vqfq98	279	14	the	the	DT
cord-016903-z2vqfq98	279	15	elderly	elderly	JJ
cord-016903-z2vqfq98	279	16	:	:	:
cord-016903-z2vqfq98	279	17	do	do	VBP
cord-016903-z2vqfq98	279	18	they	-PRON-	PRP
cord-016903-z2vqfq98	279	19	live	live	VB
cord-016903-z2vqfq98	279	20	up	up	IN
cord-016903-z2vqfq98	279	21	to	to	IN
cord-016903-z2vqfq98	279	22	their	-PRON-	PRP$
cord-016903-z2vqfq98	279	23	promise	promise	NN
cord-016903-z2vqfq98	279	24	The	the	DT
cord-016903-z2vqfq98	279	25	authors	author	NNS
cord-016903-z2vqfq98	279	26	wish	wish	VBP
cord-016903-z2vqfq98	279	27	to	to	TO
cord-016903-z2vqfq98	279	28	acknowledge	acknowledge	VB
cord-016903-z2vqfq98	279	29	the	the	DT
cord-016903-z2vqfq98	279	30	support	support	NN
cord-016903-z2vqfq98	279	31	ofthe	ofthe	DT
cord-016903-z2vqfq98	279	32	Austrian	Austrian	NNP
cord-016903-z2vqfq98	279	33	Science	Science	NNP
cord-016903-z2vqfq98	279	34	Fund	Fund	NNP
cord-016903-z2vqfq98	279	35	and	and	CC
cord-016903-z2vqfq98	279	36	the	the	DT
cord-016903-z2vqfq98	279	37	Austrian	Austrian	NNP
cord-016903-z2vqfq98	279	38	Green	Green	NNP
cord-016903-z2vqfq98	279	39	Cross	Cross	NNP
cord-016903-z2vqfq98	279	40	Society	Society	NNP
cord-016903-z2vqfq98	279	41	for	for	IN
cord-016903-z2vqfq98	279	42	Preventive	Preventive	NNP
cord-016903-z2vqfq98	279	43	Medicine	Medicine	NNP
cord-016903-z2vqfq98	279	44	.	.	.