id author title date pages extension mime words sentences flesch summary cache txt cord-333340-ekok0mp5 Graf, Erin H. Appropriate Use and Future Directions of Molecular Diagnostic Testing 2020-02-06 .txt text/plain 5773 289 33 PURPOSE OF REVIEW: Major technologic advances in two main areas of molecular infectious disease diagnostics have resulted in accelerated adoption or ordering, outpacing implementation, and clinical utility studies. More studies are needed to assess their prospective impacts on patient management and antimicrobial stewardship efforts as the future state of infectious disease diagnostics will see continued expansion of these technologic advances. This review will highlight recent studies developing and applying emerging molecular infectious disease technologies and touch on limited published data on clinical utility and stewardship approaches. Ideally, we would evaluate all of these approaches via randomized controlled trials comparing patient outcomes between conventional microbiologic testing and testing including a syndromic panel; however, very limited studies addressing this have been published [8] . One of the only randomized controlled trials also found no difference in antibiotic usage, including duration, between adults tested via syndromic panel at the point-of-care compared to patients receiving conventional testing in a hospital emergency department and inpatient unit [15] . ./cache/cord-333340-ekok0mp5.txt ./txt/cord-333340-ekok0mp5.txt